## Sat Dec 13 05:43:17 2025
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/qs/new/CH2_bin.50.fa -m mmseqs --itype genome -o CH2_bin.50 --output_dir /data/result/bins/wyx/egg/CH2_bin.50 --cpu 32
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
CH2_k127_10003211_1	1163617.SCD_n00549	1.309e-24	105.0	COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,2VIWQ@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
CH2_k127_10003211_0	580332.Slit_2681	2.728e-129	430.0	COG1629@1|root,COG4771@2|Bacteria,1RA71@1224|Proteobacteria,2WGMC@28216|Betaproteobacteria,44V6B@713636|Nitrosomonadales	28216|Betaproteobacteria	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
CH2_k127_10043317_3	1163617.SCD_n00532	1.406e-20	93.0	COG2104@1|root,COG2104@2|Bacteria,1NG8E@1224|Proteobacteria,2VVVB@28216|Betaproteobacteria	28216|Betaproteobacteria	H	thiamine biosynthesis protein ThiS	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
CH2_k127_10043317_1	1163617.SCD_n02464	1.429e-166	533.0	COG4536@1|root,COG4536@2|Bacteria,1NZ99@1224|Proteobacteria,2WGFR@28216|Betaproteobacteria	28216|Betaproteobacteria	P	CBS domain containing protein	corB	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
CH2_k127_10043317_2	323848.Nmul_A2133	6.006e-81	278.0	COG4137@1|root,COG4137@2|Bacteria,1R3YD@1224|Proteobacteria,2VK0H@28216|Betaproteobacteria,371QS@32003|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM Cytochrome c assembly protein	ypjD	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
CH2_k127_10043317_0	1163617.SCD_n02462	1.341e-226	708.0	COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,2VJ3W@28216|Betaproteobacteria	28216|Betaproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
CH2_k127_10069793_0	1163617.SCD_n02486	4.535e-158	505.0	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,2VI5Q@28216|Betaproteobacteria	28216|Betaproteobacteria	D	Peptidoglycan polymerase that is essential for cell division	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
CH2_k127_10069793_1	1163617.SCD_n02487	4.022e-87	291.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,2VHJ1@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
CH2_k127_10073600_1	243233.MCA2711	2.421e-20	93.0	COG1141@1|root,COG2124@1|root,COG1141@2|Bacteria,COG2124@2|Bacteria,1MV75@1224|Proteobacteria,1RY69@1236|Gammaproteobacteria,1XFKB@135618|Methylococcales	135618|Methylococcales	C	Cytochrome P450	-	-	1.14.13.70	ko:K05917	ko00100,ko01100,ko01110,ko01130,map00100,map01100,map01110,map01130	M00101	R05640,R05731	RC01442	ko00000,ko00001,ko00002,ko00199,ko01000	-	-	-	p450
CH2_k127_10073600_0	243233.MCA1013	5.41e-288	904.0	COG1033@1|root,COG1033@2|Bacteria,1QW3H@1224|Proteobacteria,1RZA3@1236|Gammaproteobacteria,1XDIY@135618|Methylococcales	1236|Gammaproteobacteria	S	TIGRFAM Hopanoid biosynthesis associated RND transporter like protein HpnN	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
CH2_k127_1008240_0	580332.Slit_0533	1.947e-76	263.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,2VJ72@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Adenylyl cyclase class-3 4 guanylyl cyclase	cyaA	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
CH2_k127_1008240_1	1163617.SCD_n02328	5.454e-46	171.0	COG1186@1|root,COG1186@2|Bacteria,1RH75@1224|Proteobacteria,2VSE7@28216|Betaproteobacteria	28216|Betaproteobacteria	J	chain release factor	yaeJ	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
CH2_k127_1008240_2	1485544.JQKP01000003_gene248	2.865e-18	89.0	2E4TM@1|root,32ZMZ@2|Bacteria,1NAT5@1224|Proteobacteria,2VXD9@28216|Betaproteobacteria,44WMC@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_10116253_3	1163617.SCD_n00280	1.989e-18	85.0	COG0537@1|root,COG0537@2|Bacteria,1MZVD@1224|Proteobacteria,2VU7S@28216|Betaproteobacteria	28216|Betaproteobacteria	FG	Histidine triad (Hit) protein	hit	-	-	-	-	-	-	-	-	-	-	-	HIT
CH2_k127_10116253_1	1163617.SCD_n00281	6.895e-126	421.0	2A8Z1@1|root,30Y2U@2|Bacteria,1PJYG@1224|Proteobacteria,2VJ83@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_10116253_0	1163617.SCD_n00282	5.775e-153	495.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,2VIBV@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF3329,HATPase_c,HisKA,PAS,PAS_8
CH2_k127_10116253_4	1121403.AUCV01000030_gene2788	8.849e-09	68.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR,PSII_BNR,Sortilin-Vps10
CH2_k127_10116253_2	208444.JNYY01000007_gene7930	1.053e-28	132.0	COG0070@1|root,COG0070@2|Bacteria,2IB5W@201174|Actinobacteria,4ECR7@85010|Pseudonocardiales	201174|Actinobacteria	E	glutamate synthase	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_1022558_15	105559.Nwat_0660	9.785e-12	66.0	COG0354@1|root,COG0354@2|Bacteria,1N852@1224|Proteobacteria,1RPWB@1236|Gammaproteobacteria,1WWK8@135613|Chromatiales	135613|Chromatiales	S	Belongs to the GcvT family	-	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
CH2_k127_1022558_13	159087.Daro_2865	4.896e-14	78.0	COG2009@1|root,COG2009@2|Bacteria,1RIGZ@1224|Proteobacteria,2VSEG@28216|Betaproteobacteria,2KWKD@206389|Rhodocyclales	206389|Rhodocyclales	C	COG2009 Succinate dehydrogenase fumarate reductase, cytochrome b subunit	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
CH2_k127_1022558_8	1163617.SCD_n01495	5.677e-32	129.0	COG2142@1|root,COG2142@2|Bacteria,1MZR9@1224|Proteobacteria,2VSJN@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Succinate dehydrogenase hydrophobic membrane anchor protein	sdhD	-	-	ko:K00242	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
CH2_k127_1022558_2	713586.KB900536_gene372	3.185e-276	859.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,1RMU2@1236|Gammaproteobacteria,1WW72@135613|Chromatiales	135613|Chromatiales	C	Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
CH2_k127_1022558_6	1123368.AUIS01000006_gene568	1.142e-87	304.0	COG2206@1|root,COG2206@2|Bacteria,1RGJH@1224|Proteobacteria,1S4PZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3391,HD_5
CH2_k127_1022558_4	1163617.SCD_n01497	4.912e-125	402.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,2VIKC@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	sdhB	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_17,Fer4_8
CH2_k127_1022558_14	261292.Nit79A3_0846	6.163e-12	71.0	COG2938@1|root,COG2938@2|Bacteria,1N7P4@1224|Proteobacteria,2VY7W@28216|Betaproteobacteria,373KF@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Flavinator of succinate dehydrogenase	-	-	-	ko:K09159	-	-	-	-	ko00000,ko02048	-	-	-	Sdh5
CH2_k127_1022558_9	1163617.SCD_n01388	2.352e-22	102.0	COG0694@1|root,COG0694@2|Bacteria,1NHWB@1224|Proteobacteria,2VXQB@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins	-	-	-	ko:K19168	-	-	-	-	ko00000,ko02048	-	-	-	-
CH2_k127_1022558_1	1163617.SCD_n01389	1.992e-286	887.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,2VHA7@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
CH2_k127_1022558_5	323848.Nmul_A1746	4.976e-100	329.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,2VHR2@28216|Betaproteobacteria,371U7@32003|Nitrosomonadales	28216|Betaproteobacteria	K	RNA polymerase sigma factor	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CH2_k127_1022558_10	395494.Galf_1185	2.951e-22	104.0	COG3073@1|root,COG3073@2|Bacteria,1QANZ@1224|Proteobacteria,2VVPR@28216|Betaproteobacteria,44VXX@713636|Nitrosomonadales	28216|Betaproteobacteria	T	PFAM Anti sigma-E protein RseA family protein	rseA	-	-	ko:K03597	-	-	-	-	ko00000,ko03021	-	-	-	RseA_N
CH2_k127_1022558_7	1163617.SCD_n01392	1.982e-85	293.0	COG3026@1|root,COG3026@2|Bacteria,1MUQ8@1224|Proteobacteria,2VMZQ@28216|Betaproteobacteria	28216|Betaproteobacteria	T	negative regulator of sigma E activity	rseB	-	-	ko:K03598	-	-	-	-	ko00000,ko03021	-	-	-	MucB_RseB,MucB_RseB_C
CH2_k127_1022558_12	765912.Thimo_1825	5.347e-20	96.0	COG3086@1|root,COG3086@2|Bacteria,1N6QS@1224|Proteobacteria,1SCTM@1236|Gammaproteobacteria,1WZDV@135613|Chromatiales	135613|Chromatiales	T	PFAM Positive regulator of sigma(E) RseC MucC	-	-	-	ko:K03803	-	-	-	-	ko00000,ko03021	-	-	-	RseC_MucC
CH2_k127_1022558_3	1163617.SCD_n01394	8.838e-201	634.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VI4Q@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Belongs to the peptidase S1C family	degQ	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
CH2_k127_1022558_11	153948.NAL212_1019	2.703e-21	97.0	COG0526@1|root,COG0526@2|Bacteria,1QVC9@1224|Proteobacteria,2VYGG@28216|Betaproteobacteria,373MH@32003|Nitrosomonadales	28216|Betaproteobacteria	CO	Glutaredoxin-like domain (DUF836)	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	DUF836
CH2_k127_1022558_0	279714.FuraDRAFT_1828	0.0	1024.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,2VHM5@28216|Betaproteobacteria,2KPWD@206351|Neisseriales	206351|Neisseriales	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
CH2_k127_1022558_16	292415.Tbd_2088	0.0002496	43.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,2VJ9D@28216|Betaproteobacteria,1KRH1@119069|Hydrogenophilales	119069|Hydrogenophilales	U	Peptidase S24-like	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
CH2_k127_10258044_1	1123393.KB891316_gene1274	6.186e-208	650.0	COG0208@1|root,COG0208@2|Bacteria,1MWUS@1224|Proteobacteria,2VI7U@28216|Betaproteobacteria,1KSIR@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	-	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
CH2_k127_10258044_0	1163617.SCD_n02088	0.0	1497.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2VJIV@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdA	GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
CH2_k127_10258044_2	1163617.SCD_n02093	4.134e-152	484.0	COG0788@1|root,COG0788@2|Bacteria,1MVCF@1224|Proteobacteria,2VIXE@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)	purU	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	ACT,Formyl_trans_N
CH2_k127_10258044_3	1121422.AUMW01000008_gene476	1.116e-66	237.0	COG5001@1|root,COG5001@2|Bacteria	2|Bacteria	T	cyclic-guanylate-specific phosphodiesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_9,Response_reg
CH2_k127_10300002_11	331869.BAL199_00365	2.506e-08	61.0	2EU1Z@1|root,33MJ0@2|Bacteria,1NNW2@1224|Proteobacteria,2UWP4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_10300002_4	1121935.AQXX01000130_gene2408	4.057e-31	130.0	COG5492@1|root,COG5492@2|Bacteria,1NPVV@1224|Proteobacteria	1224|Proteobacteria	N	Phage tail tube protein, TTP	-	-	-	-	-	-	-	-	-	-	-	-	Phage_tail_3
CH2_k127_10300002_5	754331.AEME01000001_gene3965	4.25e-26	125.0	COG1196@1|root,COG5281@1|root,COG1196@2|Bacteria,COG5281@2|Bacteria,1MU81@1224|Proteobacteria,1RS6P@1236|Gammaproteobacteria,3XQ8T@561|Escherichia	1236|Gammaproteobacteria	D	Prophage tail length tape measure protein	ynaA	-	-	-	-	-	-	-	-	-	-	-	TMP_2,Tape_meas_lam_C
CH2_k127_10300002_7	1177928.TH2_05248	4.903e-25	109.0	2EDKQ@1|root,337GJ@2|Bacteria,1NAT9@1224|Proteobacteria,2UT7K@28211|Alphaproteobacteria,2JX26@204441|Rhodospirillales	204441|Rhodospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_10300002_2	1177928.TH2_05218	1.442e-50	184.0	2C095@1|root,32VKM@2|Bacteria,1N0Y9@1224|Proteobacteria,2UJ59@28211|Alphaproteobacteria,2JYQC@204441|Rhodospirillales	204441|Rhodospirillales	S	Domain of unknown function (DUF1833)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1833
CH2_k127_10300002_6	269482.Bcep1808_3223	2.917e-25	109.0	COG0791@1|root,COG0791@2|Bacteria,1NA3R@1224|Proteobacteria,2VXXX@28216|Betaproteobacteria,1KEQ6@119060|Burkholderiaceae	28216|Betaproteobacteria	M	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60
CH2_k127_10300002_0	1000565.METUNv1_01675	1.653e-273	867.0	COG4733@1|root,COG4733@2|Bacteria,1MXXZ@1224|Proteobacteria,2VJEP@28216|Betaproteobacteria	28216|Betaproteobacteria	NT	Phage-related protein, tail	-	-	-	-	-	-	-	-	-	-	-	-	DUF1983,Phage-tail_3
CH2_k127_10300002_9	272942.RCAP_rcc02906	1.445e-11	74.0	298S1@1|root,2ZVWB@2|Bacteria,1P7CD@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_10300002_3	640511.BC1002_6569	7.138e-37	143.0	COG3108@1|root,COG3108@2|Bacteria,1N1HE@1224|Proteobacteria,2VTZR@28216|Betaproteobacteria,1K8H9@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Peptidase M15	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_3
CH2_k127_10300002_8	743721.Psesu_1123	6.143e-15	82.0	2DTVY@1|root,33MW8@2|Bacteria,1P6ST@1224|Proteobacteria,1SU01@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_10300002_1	637389.Acaty_c1937	4.733e-91	309.0	COG0582@1|root,COG0582@2|Bacteria,1MWBN@1224|Proteobacteria,1RPD0@1236|Gammaproteobacteria,2NDRM@225057|Acidithiobacillales	225057|Acidithiobacillales	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
CH2_k127_10300002_13	1497679.EP56_05540	5.007e-05	50.0	COG3311@1|root,COG3311@2|Bacteria,1UPKJ@1239|Firmicutes	1239|Firmicutes	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
CH2_k127_10315296_2	1163617.SCD_n01184	4.858e-65	224.0	COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,2VHN9@28216|Betaproteobacteria	28216|Betaproteobacteria	L	AAA ATPase central domain protein	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
CH2_k127_10315296_0	1163617.SCD_n01185	6.246e-227	708.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,2VHJJ@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
CH2_k127_10315296_1	1163617.SCD_n01186	1.663e-196	623.0	COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,2VKSN@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella	mltF	GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944	-	ko:K18691	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	SBP_bac_3,SLT
CH2_k127_10324018_9	1163617.SCD_n01583	2.104e-41	158.0	COG3637@1|root,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OMP_b-brl,OmpA_membrane
CH2_k127_10324018_3	1123392.AQWL01000002_gene2035	6.128e-127	411.0	COG0842@1|root,COG0842@2|Bacteria,1N55T@1224|Proteobacteria,2VJ7R@28216|Betaproteobacteria,1KRKR@119069|Hydrogenophilales	119069|Hydrogenophilales	V	ABC-2 type transporter	-	-	-	ko:K09694	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC2_membrane
CH2_k127_10324018_1	1163617.SCD_n00157	7.057e-140	451.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,2VI3G@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Part of the ABC transporter complex NodIJ involved in the export of the nodulation factors (Nod factors), the bacterial signal molecules that induce symbiosis and subsequent nodulation induction. Nod factors are LCO (lipo-chitin oligosaccharide), a modified beta-1,4-linked N-acetylglucosamine oligosaccharide. This subunit is responsible for energy coupling to the transport system	nodI	-	-	ko:K01990,ko:K09695	ko02010,map02010	M00252,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.102	-	-	ABC_tran
CH2_k127_10324018_7	640081.Dsui_0725	1.313e-58	209.0	COG2945@1|root,COG2945@2|Bacteria,1MUDY@1224|Proteobacteria,2VJ8M@28216|Betaproteobacteria,2KV03@206389|Rhodocyclales	206389|Rhodocyclales	S	hydrolase of the alpha beta superfamily	-	-	-	ko:K07018	-	-	-	-	ko00000	-	-	-	Hydrolase_4,Peptidase_S15
CH2_k127_10324018_8	1163617.SCD_n00167	5.46e-47	170.0	COG3411@1|root,COG3411@2|Bacteria,1MZR4@1224|Proteobacteria,2VTY1@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Ferredoxin	fdx	-	-	-	-	-	-	-	-	-	-	-	2Fe-2S_thioredx
CH2_k127_10324018_10	497321.C664_12460	1.97e-38	146.0	COG1694@1|root,COG1694@2|Bacteria,1N02D@1224|Proteobacteria,2VU39@28216|Betaproteobacteria,2KX0C@206389|Rhodocyclales	206389|Rhodocyclales	S	MazG-like family	-	-	-	-	-	-	-	-	-	-	-	-	MazG-like
CH2_k127_10324018_6	1288494.EBAPG3_28860	5.136e-84	284.0	COG1596@1|root,COG1596@2|Bacteria,1RFBH@1224|Proteobacteria,2VKB3@28216|Betaproteobacteria,3726E@32003|Nitrosomonadales	28216|Betaproteobacteria	M	Polysaccharide biosynthesis/export protein	wza	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
CH2_k127_10324018_0	292415.Tbd_0282	2.825e-180	578.0	COG3206@1|root,COG3206@2|Bacteria,1MVBX@1224|Proteobacteria,2VMDA@28216|Betaproteobacteria,1KSI5@119069|Hydrogenophilales	119069|Hydrogenophilales	M	G-rich domain on putative tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GNVR
CH2_k127_10324018_5	1123393.KB891330_gene819	5.457e-109	361.0	COG0489@1|root,COG0489@2|Bacteria,1MVI9@1224|Proteobacteria,2VJEB@28216|Betaproteobacteria,1KSF2@119069|Hydrogenophilales	119069|Hydrogenophilales	D	NUBPL iron-transfer P-loop NTPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
CH2_k127_10324018_4	1163617.SCD_n02952	7.226e-125	418.0	COG5338@1|root,COG5338@2|Bacteria,1R7QB@1224|Proteobacteria,2WFN2@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_10324018_2	292415.Tbd_0285	3.579e-128	415.0	COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,2VIK1@28216|Betaproteobacteria	28216|Betaproteobacteria	U	SMART AAA ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,Epimerase_2
CH2_k127_10382636_8	1163617.SCD_n02918	1.097e-98	328.0	COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,2VHG1@28216|Betaproteobacteria	28216|Betaproteobacteria	MU	type I secretion outer membrane protein, TolC	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
CH2_k127_10382636_14	1158762.KB898053_gene212	5.713e-39	147.0	COG0607@1|root,COG0607@2|Bacteria,1MZPW@1224|Proteobacteria,1S94C@1236|Gammaproteobacteria,1WYZS@135613|Chromatiales	135613|Chromatiales	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CH2_k127_10382636_9	1163617.SCD_n02919	8.035e-90	301.0	COG2518@1|root,COG2518@2|Bacteria,1RD6S@1224|Proteobacteria,2VJX3@28216|Betaproteobacteria	28216|Betaproteobacteria	O	protein-L-isoaspartate(D-aspartate) O-methyltransferase	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
CH2_k127_10382636_1	1163617.SCD_n02920	0.0	1184.0	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,2VHS3@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
CH2_k127_10382636_7	395494.Galf_2862	3.395e-110	362.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,2VHSA@28216|Betaproteobacteria,44VJP@713636|Nitrosomonadales	28216|Betaproteobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
CH2_k127_10382636_16	1163617.SCD_n02694	9.651e-20	89.0	COG0607@1|root,32YCZ@2|Bacteria,1N6NN@1224|Proteobacteria,2VVV9@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Sulfurtransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
CH2_k127_10382636_0	1163617.SCD_n02922	0.0	1720.0	COG0643@1|root,COG0784@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2VJSZ@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	pilL	-	-	ko:K02487,ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
CH2_k127_10382636_3	640081.Dsui_0657	6.286e-205	659.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VJBX@28216|Betaproteobacteria,2KU9U@206389|Rhodocyclales	206389|Rhodocyclales	NT	Methyl-accepting chemotaxis protein	pilJ	-	-	ko:K02660	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	MCPsignal,PilJ
CH2_k127_10382636_13	1163617.SCD_n02924	3.165e-46	173.0	COG0835@1|root,COG0835@2|Bacteria,1N07Q@1224|Proteobacteria,2VU6N@28216|Betaproteobacteria	28216|Betaproteobacteria	NT	PFAM CheW domain protein	pilI	-	-	ko:K02659	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	CheW
CH2_k127_10382636_12	1163617.SCD_n02925	1.323e-57	201.0	COG0745@1|root,COG0745@2|Bacteria,1RI9T@1224|Proteobacteria,2VSSD@28216|Betaproteobacteria	28216|Betaproteobacteria	T	RESPONSE REGULATOR receiver	pilH	-	-	ko:K02658	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	Response_reg
CH2_k127_10382636_10	1163617.SCD_n02926	4.375e-68	233.0	COG0745@1|root,COG0745@2|Bacteria,1RDYB@1224|Proteobacteria,2VR2Q@28216|Betaproteobacteria	28216|Betaproteobacteria	T	RESPONSE REGULATOR receiver	pilG	-	-	ko:K02657	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	Response_reg
CH2_k127_10382636_15	1005048.CFU_0792	2.549e-27	113.0	COG1773@1|root,COG1773@2|Bacteria,1N731@1224|Proteobacteria,2VVP4@28216|Betaproteobacteria,474ZG@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Rubredoxin	rubA	-	-	-	-	-	-	-	-	-	-	-	Rubredoxin
CH2_k127_10382636_5	1163617.SCD_n02927	7.927e-131	422.0	COG0351@1|root,COG0351@2|Bacteria,1MU9J@1224|Proteobacteria,2VKD2@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
CH2_k127_10382636_11	1163617.SCD_n02928	1.285e-63	225.0	COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,2VSR5@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
CH2_k127_10382636_2	1163617.SCD_n02929	1.439e-219	687.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,2VHK9@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Aminotransferase	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CH2_k127_10382636_4	1163617.SCD_n02932	2.086e-132	434.0	28KIA@1|root,2ZA3I@2|Bacteria,1MXIF@1224|Proteobacteria,2W16H@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_10382636_6	1123392.AQWL01000002_gene1939	5.395e-119	383.0	COG0755@1|root,COG0755@2|Bacteria,1RG6M@1224|Proteobacteria,2VI4N@28216|Betaproteobacteria,1KRWH@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Cytochrome C assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
CH2_k127_10399002_1	1163617.SCD_n01259	5.853e-314	970.0	COG0443@1|root,COG0443@2|Bacteria,1MVQI@1224|Proteobacteria,2VHGV@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB	hscA	GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141	-	ko:K04044	-	-	-	-	ko00000,ko03110	1.A.33	-	-	HSP70
CH2_k127_10399002_4	1163617.SCD_n01260	8.042e-56	196.0	COG0633@1|root,COG0633@2|Bacteria,1RHDC@1224|Proteobacteria,2VSQE@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Ferredoxin 2Fe-2S type, ISC system	fdx	-	-	ko:K04755	-	-	-	-	ko00000	-	-	-	Fer2
CH2_k127_10399002_6	998674.ATTE01000001_gene4333	1.504e-28	118.0	COG2975@1|root,COG2975@2|Bacteria,1N7C1@1224|Proteobacteria,1SC9F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Fe-S assembly protein IscX	iscX	GO:0003674,GO:0004857,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0030234,GO:0031163,GO:0043086,GO:0043167,GO:0043169,GO:0044085,GO:0044092,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050790,GO:0051186,GO:0065007,GO:0065009,GO:0071840,GO:0098772	-	-	-	-	-	-	-	-	-	-	Fe-S_assembly
CH2_k127_10399002_3	1163617.SCD_n01262	8.248e-153	491.0	COG1377@1|root,COG1377@2|Bacteria,1MUWI@1224|Proteobacteria,2VIH0@28216|Betaproteobacteria	28216|Betaproteobacteria	N	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhB	-	-	ko:K02401	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_2
CH2_k127_10399002_0	1163617.SCD_n01263	0.0	1041.0	COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,2VHVC@28216|Betaproteobacteria	28216|Betaproteobacteria	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
CH2_k127_10399002_2	1163617.SCD_n01264	2.135e-161	519.0	COG1419@1|root,COG1419@2|Bacteria,1MUQW@1224|Proteobacteria,2VHVZ@28216|Betaproteobacteria	28216|Betaproteobacteria	N	PFAM GTP-binding signal recognition particle SRP54 G- domain	flhF	-	-	ko:K02404	-	-	-	-	ko00000,ko02035	-	-	-	SRP54
CH2_k127_10399002_5	1163617.SCD_n01265	7.299e-30	121.0	COG0455@1|root,COG0455@2|Bacteria,1R8IW@1224|Proteobacteria,2VRTK@28216|Betaproteobacteria	28216|Betaproteobacteria	D	Belongs to the ParA family	fleN	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	AAA_31,CbiA,ParA
CH2_k127_10400967_2	1163617.SCD_n00540	1.431e-35	136.0	COG1179@1|root,COG1179@2|Bacteria,1MWXR@1224|Proteobacteria,2VJPP@28216|Betaproteobacteria	28216|Betaproteobacteria	H	UBA THIF-type NAD FAD binding protein	moeB	-	-	ko:K22132	-	-	-	-	ko00000,ko03016	-	-	-	ThiF
CH2_k127_10400967_0	395495.Lcho_0061	5.571e-93	319.0	COG2143@1|root,COG2143@2|Bacteria,1RB3S@1224|Proteobacteria,2VX2X@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Thioredoxin-like	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	Thioredoxin_2
CH2_k127_10400967_1	1163617.SCD_n00548	4.744e-78	264.0	COG3576@1|root,COG3576@2|Bacteria,1R8RC@1224|Proteobacteria,2VRYE@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Pfam:Pyridox_oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
CH2_k127_10401635_5	1163617.SCD_n00784	3.777e-15	75.0	2CDCV@1|root,308Y1@2|Bacteria,1N74F@1224|Proteobacteria,2VSMP@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_10401635_1	1163617.SCD_n00785	1.037e-175	558.0	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,2VJRR@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
CH2_k127_10401635_4	555779.Dthio_PD2693	1.221e-20	94.0	2DSSK@1|root,33H9W@2|Bacteria	2|Bacteria	K	SpoVT / AbrB like domain	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
CH2_k127_10401635_3	555779.Dthio_PD2692	1.137e-37	145.0	2DS2U@1|root,33E9F@2|Bacteria,1PAXB@1224|Proteobacteria	1224|Proteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
CH2_k127_10401635_2	1163617.SCD_n00786	2.913e-86	289.0	COG0625@1|root,COG0625@2|Bacteria,1RHSK@1224|Proteobacteria,2VIJ5@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Glutathione S-transferase	yibF	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N_3
CH2_k127_10401635_0	1163617.SCD_n00787	1.792e-205	643.0	COG1049@1|root,COG1049@2|Bacteria,1MVCR@1224|Proteobacteria,2VHT2@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Belongs to the aconitase IPM isomerase family	acnB	-	4.2.1.3,4.2.1.99	ko:K01682	ko00020,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173	R01324,R01325,R01900,R04425	RC00497,RC00498,RC00618,RC01153	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_2_N,Aconitase_B_N
CH2_k127_10462960_1	1163617.SCD_n02568	1.138e-153	492.0	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,2VICG@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
CH2_k127_10462960_0	1163617.SCD_n02569	2.302e-190	597.0	COG0752@1|root,COG0752@2|Bacteria,1MVCJ@1224|Proteobacteria,2VIQX@28216|Betaproteobacteria	28216|Betaproteobacteria	J	glycyl-tRNA synthetase alpha subunit	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2e
CH2_k127_10462960_2	1163617.SCD_n02571	4.532e-111	367.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,2VH1I@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
CH2_k127_10557951_7	1123393.KB891316_gene1991	4.268e-48	172.0	COG1850@1|root,COG1850@2|Bacteria,1MWEB@1224|Proteobacteria,2VJF4@28216|Betaproteobacteria,1KST0@119069|Hydrogenophilales	119069|Hydrogenophilales	G	Ribulose bisphosphate carboxylase large chain, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	RuBisCO_large,RuBisCO_large_N
CH2_k127_10557951_4	580332.Slit_0986	2.435e-69	237.0	COG4451@1|root,COG4451@2|Bacteria,1R9ZE@1224|Proteobacteria,2VRRB@28216|Betaproteobacteria,44WEJ@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Ribulose bisphosphate carboxylase, small chain	cbbS	-	4.1.1.39	ko:K01602	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_small
CH2_k127_10557951_2	1123393.KB891316_gene1989	1.366e-165	522.0	COG0714@1|root,COG0714@2|Bacteria,1MXIW@1224|Proteobacteria,2VHWI@28216|Betaproteobacteria,1KS5K@119069|Hydrogenophilales	119069|Hydrogenophilales	S	CbbQ/NirQ/NorQ C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5,CbbQ_C
CH2_k127_10557951_0	266264.Rmet_1498	0.0	1417.0	COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,2VJJW@28216|Betaproteobacteria	28216|Betaproteobacteria	P	von Willebrand factor, type A	cbbO	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
CH2_k127_10557951_6	1163617.SCD_n02035	1.688e-51	183.0	2E0T4@1|root,32WAV@2|Bacteria,1N19Z@1224|Proteobacteria,2VTHM@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_10557951_5	1163617.SCD_n02036	2.779e-66	228.0	2AE70@1|root,3140Y@2|Bacteria,1RK0Q@1224|Proteobacteria,2VSEF@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_10557951_3	1163617.SCD_n02037	8.956e-71	242.0	COG3223@1|root,COG3223@2|Bacteria,1N0MS@1224|Proteobacteria,2VUQQ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Phosphate-starvation-inducible E	-	-	-	ko:K13256	-	-	-	-	ko00000	-	-	-	PsiE
CH2_k127_10557951_1	1163617.SCD_n02039	7.361e-251	783.0	COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,2VI9F@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
CH2_k127_10647607_4	1163617.SCD_n00310	7.01e-39	146.0	COG1832@1|root,COG1832@2|Bacteria,1N03D@1224|Proteobacteria,2VU9G@28216|Betaproteobacteria	28216|Betaproteobacteria	S	coa-binding	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
CH2_k127_10647607_2	1163617.SCD_n00308	4.123e-124	407.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,2VICZ@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Lipid A Biosynthesis	htrB	-	2.3.1.241,2.3.1.242	ko:K02517,ko:K12974	ko00540,ko01100,map00540,map01100	M00060	R05146,R10906	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
CH2_k127_10647607_3	1163617.SCD_n00308	1.221e-109	366.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,2VICZ@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Lipid A Biosynthesis	htrB	-	2.3.1.241,2.3.1.242	ko:K02517,ko:K12974	ko00540,ko01100,map00540,map01100	M00060	R05146,R10906	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
CH2_k127_10647607_1	1163617.SCD_n00307	5.417e-207	648.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,2VH7U@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
CH2_k127_10647607_0	85643.Tmz1t_3842	5.121e-236	734.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,2VH57@28216|Betaproteobacteria,2KVI2@206389|Rhodocyclales	206389|Rhodocyclales	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
CH2_k127_10663717_2	207954.MED92_14423	1.549e-08	61.0	COG2199@1|root,COG3829@1|root,COG2199@2|Bacteria,COG3829@2|Bacteria,1MVSA@1224|Proteobacteria,1RP1K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	yeaP	GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0052621	2.7.7.65	ko:K13069,ko:K21021	ko02025,map02025	-	R08057	-	ko00000,ko00001,ko01000	-	-	-	GAF,GAF_2,GAF_3,GGDEF
CH2_k127_10663717_1	748247.AZKH_4480	7.583e-65	229.0	COG0745@1|root,COG0745@2|Bacteria,1RBJ1@1224|Proteobacteria,2VMZX@28216|Betaproteobacteria,2KW4A@206389|Rhodocyclales	206389|Rhodocyclales	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CH2_k127_10663717_0	326427.Cagg_0839	3.126e-152	526.0	COG0745@1|root,COG2202@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG5002@2|Bacteria,2GBK6@200795|Chloroflexi,3770Y@32061|Chloroflexia	32061|Chloroflexia	T	SMART PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_3,HATPase_c,HisKA,PAS_9,Response_reg
CH2_k127_10720099_12	1123392.AQWL01000001_gene1588	2.556e-41	154.0	COG0693@1|root,COG0693@2|Bacteria,1N7T2@1224|Proteobacteria,2VS5Q@28216|Betaproteobacteria,1KSPI@119069|Hydrogenophilales	119069|Hydrogenophilales	S	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
CH2_k127_10720099_10	1123393.KB891316_gene1128	3.129e-57	203.0	COG0517@1|root,COG0517@2|Bacteria,1N0H3@1224|Proteobacteria,2VQEB@28216|Betaproteobacteria,1KS4V@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
CH2_k127_10720099_7	1123392.AQWL01000001_gene1590	4.431e-73	250.0	COG1416@1|root,COG1416@2|Bacteria,1RHW0@1224|Proteobacteria,2VWXN@28216|Betaproteobacteria,1KSFB@119069|Hydrogenophilales	119069|Hydrogenophilales	S	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
CH2_k127_10720099_4	1123392.AQWL01000001_gene1591	5e-92	310.0	COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,2VINY@28216|Betaproteobacteria,1KSTN@119069|Hydrogenophilales	119069|Hydrogenophilales	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
CH2_k127_10720099_16	1163617.SCD_n00500	8.042e-23	102.0	COG3255@1|root,COG3255@2|Bacteria,1N93W@1224|Proteobacteria,2WHTH@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Chemoreceptor zinc-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CZB
CH2_k127_10720099_9	292415.Tbd_1841	2.543e-61	215.0	COG2154@1|root,COG2154@2|Bacteria,1MZ5Q@1224|Proteobacteria,2VVZF@28216|Betaproteobacteria,1KT6N@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Pterin 4 alpha carbinolamine dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
CH2_k127_10720099_13	1123393.KB891316_gene1123	7.049e-36	138.0	COG2010@1|root,COG2010@2|Bacteria,1N71Z@1224|Proteobacteria,2VWE5@28216|Betaproteobacteria,1KT8P@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_10720099_3	1123393.KB891316_gene1122	3.675e-96	317.0	COG1949@1|root,COG1949@2|Bacteria,1R9WX@1224|Proteobacteria,2VIA2@28216|Betaproteobacteria,1KRKK@119069|Hydrogenophilales	119069|Hydrogenophilales	A	EXOIII	orn	-	-	ko:K13288	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	RNase_T
CH2_k127_10720099_0	1163617.SCD_n01935	0.0	1231.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,2VM4W@28216|Betaproteobacteria	28216|Betaproteobacteria	G	alpha-glucan phosphorylase	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
CH2_k127_10720099_15	243365.CV_2438	4.061e-31	125.0	COG0640@1|root,COG0640@2|Bacteria,1MZAU@1224|Proteobacteria,2VTXZ@28216|Betaproteobacteria,2KS3J@206351|Neisseriales	206351|Neisseriales	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20
CH2_k127_10720099_11	243233.MCA2265	4.422e-54	194.0	COG0346@1|root,COG0346@2|Bacteria,1RHIV@1224|Proteobacteria,1S6V6@1236|Gammaproteobacteria,1XF5Q@135618|Methylococcales	135618|Methylococcales	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CH2_k127_10720099_8	1123393.KB891329_gene943	1.61e-69	239.0	COG0394@1|root,COG0394@2|Bacteria,1REU2@1224|Proteobacteria,2VS5B@28216|Betaproteobacteria,1KRQX@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Low molecular weight phosphatase family	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
CH2_k127_10720099_5	1123393.KB891329_gene944	8.441e-77	260.0	COG0394@1|root,COG0394@2|Bacteria,1MWYQ@1224|Proteobacteria,2VI3V@28216|Betaproteobacteria,1KSQ1@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Low molecular weight phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	LMWPc
CH2_k127_10720099_1	1123393.KB891329_gene945	1.055e-205	645.0	COG0798@1|root,COG0798@2|Bacteria,1MUXY@1224|Proteobacteria,2VHWA@28216|Betaproteobacteria,1KSTF@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Sodium Bile acid symporter family	-	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
CH2_k127_10720099_14	1123393.KB891316_gene1078	1.751e-34	134.0	2E1DK@1|root,32WSU@2|Bacteria,1N3VJ@1224|Proteobacteria,2VV0D@28216|Betaproteobacteria,1KTBR@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_10720099_18	1236959.BAMT01000006_gene262	8.224e-07	59.0	2DKZI@1|root,310D6@2|Bacteria,1QV1U@1224|Proteobacteria,2VQ0G@28216|Betaproteobacteria,2KP95@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_10720099_19	1123393.KB891316_gene1077	0.000408	43.0	2DKZI@1|root,310D6@2|Bacteria,1QV1U@1224|Proteobacteria,2VQ0G@28216|Betaproteobacteria,1KSK5@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_10720099_6	1123392.AQWL01000009_gene1024	3.719e-74	254.0	COG1704@1|root,COG1704@2|Bacteria,1R9YG@1224|Proteobacteria,2VQ2A@28216|Betaproteobacteria,1KSTQ@119069|Hydrogenophilales	119069|Hydrogenophilales	S	LemA family	-	-	-	-	-	-	-	-	-	-	-	-	LemA
CH2_k127_10720099_2	1123393.KB891316_gene1075	2.812e-157	507.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,2VI90@28216|Betaproteobacteria,1KRST@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Iron-containing alcohol dehydrogenase	-	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
CH2_k127_10720099_17	1121091.AUMP01000054_gene3367	4.067e-11	64.0	2DREZ@1|root,33BFB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_10846960_2	1163617.SCD_n00175	6.705e-59	211.0	COG1309@1|root,COG1309@2|Bacteria,1N27W@1224|Proteobacteria,2VY4I@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CH2_k127_10846960_1	1163617.SCD_n02992	2.005e-87	296.0	COG0265@1|root,COG0265@2|Bacteria,1R9ZV@1224|Proteobacteria,2VQ55@28216|Betaproteobacteria	28216|Betaproteobacteria	O	peptidase S1 and S6, chymotrypsin Hap	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
CH2_k127_10846960_0	1288494.EBAPG3_26540	8.96e-118	384.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,2VHFX@28216|Betaproteobacteria,371M1@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,RMMBL
CH2_k127_10970541_1	1163617.SCD_n00861	5.628e-197	621.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria	28216|Betaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.9	ko:K01539	ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978	-	-	-	ko00000,ko00001,ko01000,ko04147	3.A.3.1	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
CH2_k127_10970541_4	1163617.SCD_n00864	4.062e-55	196.0	arCOG05276@1|root,3195F@2|Bacteria,1RHZA@1224|Proteobacteria,2VSYY@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_10970541_5	573413.Spirs_3569	2.243e-14	78.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	bta	-	1.8.1.8	ko:K03671,ko:K03672	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko01000,ko03110	-	-	-	Thioredoxin,TraF
CH2_k127_10970541_3	497321.C664_02875	1.052e-56	202.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2VSEZ@28216|Betaproteobacteria,2KWKR@206389|Rhodocyclales	206389|Rhodocyclales	K	Belongs to the P(II) protein family	glnB	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
CH2_k127_10970541_0	582744.Msip34_0908	1.152e-210	668.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,2VJ8C@28216|Betaproteobacteria,2KKUX@206350|Nitrosomonadales	206350|Nitrosomonadales	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.1.5,6.3.5.1	ko:K01916,ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00189,R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
CH2_k127_10970541_2	1163617.SCD_n01848	5.644e-101	331.0	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,2VH1U@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
CH2_k127_10990288_0	76114.ebA5427	4.977e-170	542.0	COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,2VIS0@28216|Betaproteobacteria,2KUN7@206389|Rhodocyclales	206389|Rhodocyclales	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
CH2_k127_10990288_1	580332.Slit_1975	8.098e-162	520.0	COG2206@1|root,COG2206@2|Bacteria,1MW7F@1224|Proteobacteria,2VHR0@28216|Betaproteobacteria,44V3Y@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Domain of unknown function (DUF3391)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3391,HD,HD_5
CH2_k127_10990288_2	857087.Metme_4433	3.478e-75	263.0	COG0666@1|root,COG0666@2|Bacteria,1PEPV@1224|Proteobacteria,1SFWB@1236|Gammaproteobacteria,1XFT1@135618|Methylococcales	135618|Methylococcales	S	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2
CH2_k127_10990288_4	671143.DAMO_1964	2.785e-26	120.0	2C6PK@1|root,33JBS@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_10990288_3	757424.Hsero_2420	5.648e-28	120.0	2DPR1@1|root,3331B@2|Bacteria,1NA5C@1224|Proteobacteria,2WG02@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_11008081_13	666685.R2APBS1_2439	8.461e-13	70.0	COG1187@1|root,COG1187@2|Bacteria,1REW2@1224|Proteobacteria,1S6WY@1236|Gammaproteobacteria,1X34K@135614|Xanthomonadales	135614|Xanthomonadales	J	Belongs to the pseudouridine synthase RsuA family	rsuA1	-	5.4.99.21	ko:K06182	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	S4
CH2_k127_11008081_4	1163617.SCD_n02337	9.319e-92	305.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,2VQ3Z@28216|Betaproteobacteria	28216|Betaproteobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	-	5.2.1.8	ko:K01802,ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
CH2_k127_11008081_9	296591.Bpro_5381	1.554e-39	148.0	COG3549@1|root,COG3549@2|Bacteria,1MZ4I@1224|Proteobacteria,2VUSH@28216|Betaproteobacteria,4AFF9@80864|Comamonadaceae	28216|Betaproteobacteria	S	RelE-like toxin of type II toxin-antitoxin system HigB	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
CH2_k127_11008081_12	1216976.AX27061_3650	2.716e-26	110.0	COG3093@1|root,COG3093@2|Bacteria,1MZZ0@1224|Proteobacteria,2W480@28216|Betaproteobacteria,3T9FG@506|Alcaligenaceae	28216|Betaproteobacteria	K	Helix-turn-helix	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
CH2_k127_11008081_3	497321.C664_15408	1.917e-109	361.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,2VHBD@28216|Betaproteobacteria,2KVKQ@206389|Rhodocyclales	206389|Rhodocyclales	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
CH2_k127_11008081_10	1452718.JBOY01000058_gene1827	5.524e-39	149.0	COG1585@1|root,COG1585@2|Bacteria,1N4FG@1224|Proteobacteria,1S4V9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	OU	COG1585 Membrane protein implicated in regulation of membrane protease activity	-	-	-	ko:K07340	-	-	-	-	ko00000	-	-	-	NfeD
CH2_k127_11008081_2	265072.Mfla_0467	1.496e-114	375.0	COG0639@1|root,COG0639@2|Bacteria,1MV10@1224|Proteobacteria,2VHV6@28216|Betaproteobacteria,2KKMZ@206350|Nitrosomonadales	206350|Nitrosomonadales	T	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP	apaH	-	3.6.1.41	ko:K01525	ko00230,map00230	-	R00125	RC00002	ko00000,ko00001,ko01000	-	-	-	Metallophos
CH2_k127_11008081_6	266264.Rmet_2738	1.621e-60	218.0	COG0204@1|root,COG0204@2|Bacteria,1N2DG@1224|Proteobacteria,2VSJD@28216|Betaproteobacteria,1K2JJ@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Acyltransferase	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
CH2_k127_11008081_7	1163617.SCD_n02775	1.104e-56	201.0	COG3133@1|root,COG3133@2|Bacteria,1RJWY@1224|Proteobacteria,2WE8P@28216|Betaproteobacteria	28216|Betaproteobacteria	M	17 kDa surface antigen	slyB	-	-	ko:K06077	-	-	-	-	ko00000	-	-	-	Rick_17kDa_Anti
CH2_k127_11008081_1	1163617.SCD_n02776	2.477e-160	509.0	COG0524@1|root,COG0524@2|Bacteria,1PDQE@1224|Proteobacteria,2VHMF@28216|Betaproteobacteria	28216|Betaproteobacteria	G	PFAM PfkB domain protein	adoK	-	2.7.1.15,2.7.1.20	ko:K00852,ko:K00856	ko00030,ko00230,ko01100,map00030,map00230,map01100	-	R00185,R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
CH2_k127_11008081_8	1163617.SCD_n02777	4.691e-42	158.0	COG0818@1|root,COG0818@2|Bacteria,1MZ3Q@1224|Proteobacteria,2VU5Y@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Recycling of diacylglycerol produced during the turnover of membrane phospholipid	-	-	2.7.1.107	ko:K00901	ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
CH2_k127_11008081_0	1266925.JHVX01000016_gene177	8.479e-269	832.0	COG1003@1|root,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,2VHQ6@28216|Betaproteobacteria,37240@32003|Nitrosomonadales	28216|Betaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	Aminotran_5,GDC-P
CH2_k127_11008081_5	1163617.SCD_n02779	6.742e-67	231.0	COG2077@1|root,COG2077@2|Bacteria,1RAJ9@1224|Proteobacteria,2VQ18@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides	tpx	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	Redoxin
CH2_k127_11008081_11	1123392.AQWL01000002_gene1930	7.973e-34	131.0	COG0403@1|root,COG0403@2|Bacteria,1MVC1@1224|Proteobacteria,2VKQB@28216|Betaproteobacteria,1KSW6@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Glycine cleavage system P-protein	-	-	-	-	-	-	-	-	-	-	-	-	GDC-P
CH2_k127_1123008_4	1163617.SCD_n02840	1.15e-77	262.0	COG0548@1|root,COG1246@1|root,COG0548@2|Bacteria,COG1246@2|Bacteria,1MUUP@1224|Proteobacteria,2VGZC@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Belongs to the acetyltransferase family. ArgA subfamily	argA	-	2.3.1.1	ko:K14682	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,Acetyltransf_1
CH2_k127_1123008_3	1163617.SCD_n02841	3.43e-93	312.0	COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,2VJS2@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
CH2_k127_1123008_2	1163617.SCD_n02842	1.228e-100	331.0	COG1225@1|root,COG1225@2|Bacteria,1R9YF@1224|Proteobacteria,2VN9B@28216|Betaproteobacteria	28216|Betaproteobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CH2_k127_1123008_1	1163617.SCD_n02843	6.035e-119	387.0	COG0483@1|root,COG0483@2|Bacteria,1NFR1@1224|Proteobacteria,2VMQ4@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Inositol-1-monophosphatase	suhB2	-	3.1.3.25,3.1.3.7	ko:K01082,ko:K01092	ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070	M00131	R00188,R00508,R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	Inositol_P
CH2_k127_1123008_0	1163617.SCD_n02844	1.074e-152	482.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,2VHNX@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
CH2_k127_11231776_2	1163617.SCD_n01793	6.139e-103	339.0	COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,2VHF4@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Specifically methylates the ribose of guanosine 2251 in 23S rRNA	rlmB	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
CH2_k127_11231776_0	396588.Tgr7_2681	1.186e-170	569.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WVV9@135613|Chromatiales	135613|Chromatiales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9
CH2_k127_11231776_1	1163617.SCD_n00936	3.154e-123	398.0	COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,2VIRP@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
CH2_k127_11231776_5	1163617.SCD_n00937	7.38e-43	160.0	COG1314@1|root,COG1314@2|Bacteria,1N8MF@1224|Proteobacteria,2VU0P@28216|Betaproteobacteria	28216|Betaproteobacteria	U	Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
CH2_k127_11231776_3	557598.LHK_00528	1.07e-96	318.0	COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,2VIWK@28216|Betaproteobacteria,2KQGT@206351|Neisseriales	206351|Neisseriales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
CH2_k127_11231776_4	1123392.AQWL01000003_gene394	4.133e-94	314.0	COG0852@1|root,COG0852@2|Bacteria,1MX4B@1224|Proteobacteria,2VHHV@28216|Betaproteobacteria,1KRN1@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Respiratory-chain NADH dehydrogenase, 30 Kd subunit	-	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
CH2_k127_11231776_6	1552758.NC00_01945	3.737e-30	120.0	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,1RM98@1236|Gammaproteobacteria,1X3JR@135614|Xanthomonadales	135614|Xanthomonadales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa
CH2_k127_11286469_2	497965.Cyan7822_0283	2.557e-18	87.0	29ZEJ@1|root,30MDV@2|Bacteria,1G5SP@1117|Cyanobacteria,3KJYF@43988|Cyanothece	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_11286469_3	179408.Osc7112_1650	4.66e-09	61.0	COG1479@1|root,COG1479@2|Bacteria,1G3QA@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function DUF262	-	-	-	-	-	-	-	-	-	-	-	-	DUF262
CH2_k127_11286469_0	28229.ND2E_4146	1.136e-124	413.0	COG2801@1|root,COG2801@2|Bacteria,1PBHA@1224|Proteobacteria,1RQ7I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	PFAM Integrase, catalytic core	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve,rve_3
CH2_k127_11286469_1	270374.MELB17_11013	5.012e-53	191.0	COG3415@1|root,COG3415@2|Bacteria,1RFNA@1224|Proteobacteria,1S5WD@1236|Gammaproteobacteria,4685P@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	COG2963 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
CH2_k127_11289256_6	580332.Slit_1196	6.689e-89	297.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,2VJ54@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Belongs to the peptidase S16 family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_32,Lon_C
CH2_k127_11289256_3	1121004.ATVC01000004_gene1476	2.842e-126	411.0	COG0568@1|root,COG0568@2|Bacteria,1MUDI@1224|Proteobacteria,2VIUT@28216|Betaproteobacteria,2KQAU@206351|Neisseriales	206351|Neisseriales	K	RNA polymerase sigma factor	rpoS	-	-	ko:K03087	ko02026,ko05111,map02026,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
CH2_k127_11289256_7	1163617.SCD_n01119	1.746e-86	296.0	COG1388@1|root,COG4942@1|root,COG1388@2|Bacteria,COG4942@2|Bacteria,1RD24@1224|Proteobacteria,2VINR@28216|Betaproteobacteria	28216|Betaproteobacteria	DM	peptidase	-	-	-	ko:K06194	-	-	-	-	ko00000	1.A.34.1.2	-	-	LysM,Peptidase_M23
CH2_k127_11289256_5	1163617.SCD_n01118	2.543e-100	330.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,2VQ3B@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
CH2_k127_11289256_4	292415.Tbd_0835	3.875e-121	394.0	COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,2VIND@28216|Betaproteobacteria,1KRF6@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
CH2_k127_11289256_14	87626.PTD2_17885	0.0002323	46.0	2DR6A@1|root,33ACN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_11289256_10	582744.Msip34_0724	1.926e-53	190.0	COG0789@1|root,COG0789@2|Bacteria,1RGYB@1224|Proteobacteria,2VSDF@28216|Betaproteobacteria,2KMY6@206350|Nitrosomonadales	206350|Nitrosomonadales	K	PFAM regulatory protein MerR	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
CH2_k127_11289256_11	85643.Tmz1t_3019	1.022e-47	172.0	COG0776@1|root,COG0776@2|Bacteria,1RH5Z@1224|Proteobacteria,2VT12@28216|Betaproteobacteria,2KWPS@206389|Rhodocyclales	206389|Rhodocyclales	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	ihfA	-	-	ko:K04764	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
CH2_k127_11289256_1	1163617.SCD_n01113	0.0	1073.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1MWKS@1224|Proteobacteria,2VHR1@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
CH2_k127_11289256_2	265072.Mfla_1999	9.736e-173	545.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,2VIM9@28216|Betaproteobacteria,2KM6N@206350|Nitrosomonadales	206350|Nitrosomonadales	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
CH2_k127_11289256_9	1121035.AUCH01000004_gene287	3.55e-55	194.0	COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,2VRWF@28216|Betaproteobacteria,2KWC3@206389|Rhodocyclales	206389|Rhodocyclales	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
CH2_k127_11289256_12	1163617.SCD_n01110	1.15e-24	105.0	COG0291@1|root,COG0291@2|Bacteria,1N6V4@1224|Proteobacteria,2VVS9@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
CH2_k127_11289256_8	279714.FuraDRAFT_3117	2.577e-84	282.0	COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,2VQ19@28216|Betaproteobacteria,2KQWG@206351|Neisseriales	206351|Neisseriales	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
CH2_k127_11289256_0	1485544.JQKP01000010_gene825	0.0	1106.0	COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,2VHFD@28216|Betaproteobacteria,44V7H@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Threonyl and Alanyl tRNA synthetase second additional domain	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
CH2_k127_11330437_3	1163617.SCD_n01039	1.177e-51	183.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,2VGZI@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
CH2_k127_11330437_2	1163617.SCD_n01038	5.744e-96	320.0	COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,2VJRD@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
CH2_k127_11330437_1	1163617.SCD_n01037	6.826e-169	538.0	COG2956@1|root,COG2956@2|Bacteria,1MVDP@1224|Proteobacteria,2VH49@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane	lapB	-	-	ko:K19804	-	-	-	-	ko00000	-	-	-	TPR_16,TPR_7
CH2_k127_11330437_5	1163617.SCD_n01036	1.377e-26	111.0	COG5416@1|root,COG5416@2|Bacteria	2|Bacteria	FG	Lipopolysaccharide assembly protein A domain	lapA	-	-	ko:K08992	-	-	-	-	ko00000	-	-	-	LapA_dom
CH2_k127_11330437_4	153948.NAL212_2999	3.385e-44	162.0	COG0776@1|root,COG0776@2|Bacteria,1MZ7M@1224|Proteobacteria,2VSPN@28216|Betaproteobacteria,373DE@32003|Nitrosomonadales	28216|Betaproteobacteria	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	himD	-	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
CH2_k127_11330437_0	1163617.SCD_n01034	1.234e-284	879.0	COG0539@1|root,COG1093@1|root,COG0539@2|Bacteria,COG1093@2|Bacteria,1MVAV@1224|Proteobacteria,2VI12@28216|Betaproteobacteria	28216|Betaproteobacteria	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
CH2_k127_11352111_2	1123487.KB892834_gene2603	7.548e-33	127.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2VSEZ@28216|Betaproteobacteria,2KWCQ@206389|Rhodocyclales	206389|Rhodocyclales	K	Belongs to the P(II) protein family	glnK	-	-	ko:K04752	-	-	-	-	ko00000	-	-	-	P-II
CH2_k127_11352111_1	1163617.SCD_n00267	4.239e-126	409.0	2DQY9@1|root,339CR@2|Bacteria,1NR8Y@1224|Proteobacteria,2VNF6@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	Gcw_chp
CH2_k127_11352111_3	1163617.SCD_n00266	1.383e-23	102.0	COG2960@1|root,COG2960@2|Bacteria,1N7AH@1224|Proteobacteria,2VVR4@28216|Betaproteobacteria	28216|Betaproteobacteria	S	protein conserved in bacteria	yqiC	-	-	ko:K09806	-	-	-	-	ko00000	-	-	-	BMFP
CH2_k127_11352111_0	580332.Slit_0062	1.742e-230	720.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,2VHRV@28216|Betaproteobacteria,44V3K@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Magnesium chelatase, subunit ChlI C-terminal	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
CH2_k127_11391772_0	1163617.SCD_n00188	2.164e-63	225.0	COG4089@1|root,COG4089@2|Bacteria,1MV8K@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF1614)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1614
CH2_k127_11391772_3	1121946.AUAX01000026_gene6219	7.933e-17	94.0	COG1572@1|root,COG4409@1|root,COG5434@1|root,COG1572@2|Bacteria,COG4409@2|Bacteria,COG5434@2|Bacteria,2GKCR@201174|Actinobacteria,4DB3Y@85008|Micromonosporales	201174|Actinobacteria	M	Coagulation factor 5/8 C-terminal domain, discoidin domain	-	-	-	-	-	-	-	-	-	-	-	-	ASH,Beta_helix,CARDB,DUF1573,F5_F8_type_C,Pectate_lyase_3
CH2_k127_11391772_2	192952.MM_2470	5.098e-41	169.0	COG1520@1|root,COG3291@1|root,COG3391@1|root,arCOG02516@1|root,arCOG02550@1|root,arCOG02482@2157|Archaea,arCOG02508@2157|Archaea,arCOG02516@2157|Archaea,arCOG02550@2157|Archaea,arCOG02562@2157|Archaea	2157|Archaea	Q	40-residue YVTN family beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase,NosD,PKD,PQQ_2,PQQ_3,Pkinase
CH2_k127_11391772_4	62928.azo3104	2.875e-09	59.0	2EGCT@1|root,33A4K@2|Bacteria,1NPCC@1224|Proteobacteria,2VYFX@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_11391772_1	1163617.SCD_n02355	3.629e-52	186.0	COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,2VHDW@28216|Betaproteobacteria	28216|Betaproteobacteria	K	permease	perM	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
CH2_k127_11393982_0	323848.Nmul_A1809	1.32e-88	300.0	COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,2VP12@28216|Betaproteobacteria,3728I@32003|Nitrosomonadales	28216|Betaproteobacteria	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
CH2_k127_11393982_1	1163617.SCD_n01814	1.782e-34	141.0	COG3147@1|root,COG3147@2|Bacteria,1QYE8@1224|Proteobacteria,2WHED@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Sporulation related domain	-	-	-	ko:K03749	-	-	-	-	ko00000	-	-	-	SPOR
CH2_k127_11403159_3	688269.Theth_1948	2.468e-08	57.0	COG0037@1|root,COG0037@2|Bacteria,2GD3F@200918|Thermotogae	200918|Thermotogae	J	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS_C
CH2_k127_11403159_1	1163617.SCD_n01821	2.327e-180	567.0	COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,2VHS0@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
CH2_k127_11403159_0	1123368.AUIS01000009_gene2460	9.566e-226	710.0	COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,1RNCS@1236|Gammaproteobacteria,2NCDY@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Belongs to the UPF0061 (SELO) family	-	-	-	-	-	-	-	-	-	-	-	-	UPF0061
CH2_k127_11403159_2	1163617.SCD_n01093	3.882e-56	200.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,2VHHK@28216|Betaproteobacteria	28216|Betaproteobacteria	L	PFAM UMUC domain protein DNA-repair protein	umuC	-	-	ko:K03502	-	-	-	-	ko00000,ko03400	-	-	-	DUF4113,IMS,IMS_C,IMS_HHH
CH2_k127_11413008_0	1163617.SCD_n01267	5.124e-103	340.0	COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,2VNCG@28216|Betaproteobacteria	28216|Betaproteobacteria	N	PFAM MotA TolQ ExbB proton channel	motC	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
CH2_k127_11413008_1	1123393.KB891327_gene413	3.866e-95	316.0	COG1191@1|root,COG1191@2|Bacteria,1MWEU@1224|Proteobacteria,2VHR3@28216|Betaproteobacteria,1KS9X@119069|Hydrogenophilales	119069|Hydrogenophilales	K	Sigma-70 region 3	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
CH2_k127_11413008_2	1163617.SCD_n01265	1.566e-84	286.0	COG0455@1|root,COG0455@2|Bacteria,1R8IW@1224|Proteobacteria,2VRTK@28216|Betaproteobacteria	28216|Betaproteobacteria	D	Belongs to the ParA family	fleN	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	AAA_31,CbiA,ParA
CH2_k127_11417500_1	1163617.SCD_n00540	1.157e-121	394.0	COG1179@1|root,COG1179@2|Bacteria,1MWXR@1224|Proteobacteria,2VJPP@28216|Betaproteobacteria	28216|Betaproteobacteria	H	UBA THIF-type NAD FAD binding protein	moeB	-	-	ko:K22132	-	-	-	-	ko00000,ko03016	-	-	-	ThiF
CH2_k127_11417500_2	1163617.SCD_n00538	3.692e-108	355.0	COG0084@1|root,COG0084@2|Bacteria,1MW5C@1224|Proteobacteria,2VH67@28216|Betaproteobacteria	28216|Betaproteobacteria	L	PFAM TatD-related deoxyribonuclease	yjjV	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
CH2_k127_11417500_4	522306.CAP2UW1_4072	1.85e-48	179.0	COG3431@1|root,COG3431@2|Bacteria,1MZ2U@1224|Proteobacteria,2W3WB@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Phosphate-starvation-inducible E	-	-	-	-	-	-	-	-	-	-	-	-	PsiE
CH2_k127_11417500_0	472759.Nhal_1845	0.0	1065.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,1RMYC@1236|Gammaproteobacteria,1WX32@135613|Chromatiales	135613|Chromatiales	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3,LysM
CH2_k127_11417500_3	666681.M301_2748	9.951e-71	246.0	COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,2VH21@28216|Betaproteobacteria,2KKYG@206350|Nitrosomonadales	206350|Nitrosomonadales	L	TIGRFAM A G-specific adenine glycosylase	-	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
CH2_k127_11491643_4	1236959.BAMT01000006_gene430	1.58e-27	113.0	COG2854@1|root,COG2854@2|Bacteria,1NKFA@1224|Proteobacteria,2VR85@28216|Betaproteobacteria,2KME2@206350|Nitrosomonadales	206350|Nitrosomonadales	Q	PFAM toluene tolerance	-	-	-	ko:K07323	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	MlaC
CH2_k127_11491643_5	1163617.SCD_n00579	3.841e-20	94.0	COG3113@1|root,COG3113@2|Bacteria	2|Bacteria	S	response to antibiotic	-	-	-	ko:K07122	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	STAS_2
CH2_k127_11491643_1	1163617.SCD_n00580	2.632e-134	433.0	COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,2VI81@28216|Betaproteobacteria	28216|Betaproteobacteria	V	abc transporter	ybhF_1	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CH2_k127_11491643_2	1123393.KB891316_gene1169	1.194e-113	371.0	COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,2VH42@28216|Betaproteobacteria,1KRH4@119069|Hydrogenophilales	119069|Hydrogenophilales	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
CH2_k127_11491643_3	1163617.SCD_n00582	7.288e-32	127.0	COG5007@1|root,COG5007@2|Bacteria,1MZCZ@1224|Proteobacteria,2VU0K@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Belongs to the BolA IbaG family	yrbA	-	-	-	-	-	-	-	-	-	-	-	BolA
CH2_k127_11491643_0	1163617.SCD_n00584	4.046e-219	685.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,2VHZN@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
CH2_k127_11491643_6	76114.ebA2295	2.035e-05	53.0	COG3161@1|root,COG3161@2|Bacteria,1N8BF@1224|Proteobacteria,2VU5V@28216|Betaproteobacteria,2KWIC@206389|Rhodocyclales	206389|Rhodocyclales	H	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway	ubiC	-	4.1.3.40	ko:K03181	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R01302	RC00491,RC02148	ko00000,ko00001,ko00002,ko01000	-	-	-	Chor_lyase
CH2_k127_11495076_0	292415.Tbd_0652	6.668e-185	584.0	COG0508@1|root,COG1249@1|root,COG0508@2|Bacteria,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2VI6G@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Dehydrogenase	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding,Pyr_redox_2,Pyr_redox_dim
CH2_k127_11495076_2	1163617.SCD_n00983	2.318e-86	295.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,2VUP7@28216|Betaproteobacteria	28216|Betaproteobacteria	T	TIGRFAM Diguanylate cyclase	-	-	2.7.7.65	ko:K13069,ko:K21085	ko02026,map02026	-	R08057	-	ko00000,ko00001,ko01000	-	-	-	CHASE7,GGDEF,HAMP
CH2_k127_11495076_3	640081.Dsui_1237	1.3e-40	170.0	2DBUQ@1|root,2ZB76@2|Bacteria,1R4DM@1224|Proteobacteria,2VP87@28216|Betaproteobacteria,2KVUH@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_11495076_1	1163617.SCD_n01976	1.29e-87	292.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,2VJ6H@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
CH2_k127_11521109_0	1163617.SCD_n02493	1.565e-107	352.0	COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,2VIYT@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
CH2_k127_11521109_2	1163617.SCD_n02492	5.79e-35	137.0	COG3116@1|root,COG3116@2|Bacteria,1N6WK@1224|Proteobacteria,2VW1W@28216|Betaproteobacteria	28216|Betaproteobacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	ftsL	-	-	ko:K03586	-	-	-	-	ko00000,ko03036	-	-	-	FtsL
CH2_k127_11521109_1	1163617.SCD_n02491	1.984e-84	285.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,2VIZM@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Catalyzes cross-linking of the peptidoglycan cell wall at the division septum	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
CH2_k127_11553881_3	1163617.SCD_n01552	9.557e-83	289.0	COG2982@1|root,COG2982@2|Bacteria,1RD61@1224|Proteobacteria,2VS09@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Protein involved in outer membrane biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	AsmA,AsmA_2
CH2_k127_11553881_0	1123255.JHYS01000002_gene2656	4.647e-128	420.0	COG0683@1|root,COG0683@2|Bacteria,1MX94@1224|Proteobacteria,2VPP2@28216|Betaproteobacteria,4AJ4X@80864|Comamonadaceae	28216|Betaproteobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
CH2_k127_11553881_2	1158762.KB898039_gene1705	1.649e-83	303.0	COG2202@1|root,COG5002@1|root,COG2202@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1RPI4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9
CH2_k127_11553881_5	396588.Tgr7_0663	3.68e-78	270.0	COG1639@1|root,COG1639@2|Bacteria,1RCW6@1224|Proteobacteria,1S3XV@1236|Gammaproteobacteria,1WVYJ@135613|Chromatiales	135613|Chromatiales	T	signal transduction protein	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
CH2_k127_11553881_4	765914.ThisiDRAFT_0315	2.521e-78	267.0	COG1871@1|root,COG1871@2|Bacteria,1RDDB@1224|Proteobacteria,1S41X@1236|Gammaproteobacteria,1WVY2@135613|Chromatiales	135613|Chromatiales	NT	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis	cheD	-	3.5.1.44	ko:K03411	ko02030,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheD
CH2_k127_11553881_6	1123393.KB891317_gene2276	5.509e-60	209.0	COG2346@1|root,COG2346@2|Bacteria,1RH21@1224|Proteobacteria,2VSUJ@28216|Betaproteobacteria,1KT0I@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Bacterial-like globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
CH2_k127_11553881_1	1163617.SCD_n01574	3.472e-104	340.0	COG0027@1|root,COG0027@2|Bacteria,1N3KA@1224|Proteobacteria,2VH4M@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate	purT	-	2.1.2.2	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp,Epimerase
CH2_k127_11721556_4	1144319.PMI16_01926	2.895e-15	76.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,2VHR6@28216|Betaproteobacteria,472EU@75682|Oxalobacteraceae	28216|Betaproteobacteria	E	Threonine synthase N terminus	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_synth_N
CH2_k127_11721556_3	1395516.PMO01_03610	2.218e-28	123.0	COG3471@1|root,COG3471@2|Bacteria,1MZA2@1224|Proteobacteria,1S793@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	periplasmic secreted protein	Z012_10940	-	-	-	-	-	-	-	-	-	-	-	SIMPL
CH2_k127_11721556_1	1485544.JQKP01000001_gene1303	1.48e-106	355.0	COG0679@1|root,COG0679@2|Bacteria,1PHSS@1224|Proteobacteria,2VSSE@28216|Betaproteobacteria,44V9Y@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
CH2_k127_11721556_0	1163617.SCD_n00792	4.113e-148	481.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,2VHQS@28216|Betaproteobacteria	28216|Betaproteobacteria	K	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	ko:K06714	-	-	-	-	ko00000,ko03000	-	-	-	HTH_8,PAS_4,Sigma54_activat
CH2_k127_11721556_2	102125.Xen7305DRAFT_00009710	2.781e-84	299.0	2EX7V@1|root,2ZAQN@2|Bacteria,1G1M2@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_11721556_5	572477.Alvin_0350	3.062e-13	70.0	COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,1RMBU@1236|Gammaproteobacteria,1WVXU@135613|Chromatiales	135613|Chromatiales	H	Belongs to the NadC ModD family	-	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
CH2_k127_11721556_6	391612.CY0110_05637	7.69e-13	79.0	COG0515@1|root,COG0515@2|Bacteria,1G08U@1117|Cyanobacteria,3KH6Q@43988|Cyanothece	1117|Cyanobacteria	KLT	Serine Threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CH2_k127_11836558_6	1163617.SCD_n00955	4.098e-39	147.0	COG2827@1|root,COG2827@2|Bacteria,1R0EY@1224|Proteobacteria,2VWYM@28216|Betaproteobacteria	28216|Betaproteobacteria	L	GIY-YIG catalytic domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
CH2_k127_11836558_7	1485544.JQKP01000011_gene728	0.0002677	44.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,2VHN4@28216|Betaproteobacteria,44VP0@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
CH2_k127_11836558_5	748247.AZKH_2793	4.814e-44	170.0	COG1335@1|root,COG1335@2|Bacteria,1MUGW@1224|Proteobacteria,2VIMK@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Nicotinamidase	pncA	-	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
CH2_k127_11836558_3	1163617.SCD_n00518	3.734e-114	370.0	COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,2VQ1Z@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
CH2_k127_11836558_2	1163617.SCD_n00517	5.09e-127	409.0	COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,2VIGI@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
CH2_k127_11836558_1	1163617.SCD_n00516	1.462e-130	423.0	COG0631@1|root,COG0631@2|Bacteria,1MVE7@1224|Proteobacteria,2VIAV@28216|Betaproteobacteria	28216|Betaproteobacteria	T	protein phosphatase 2C domain protein	pphA	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
CH2_k127_11836558_0	1123393.KB891328_gene514	2.585e-144	464.0	COG0515@1|root,COG0515@2|Bacteria,1PJRR@1224|Proteobacteria,2VHMW@28216|Betaproteobacteria,1KSJI@119069|Hydrogenophilales	119069|Hydrogenophilales	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CH2_k127_11836558_4	1163617.SCD_n00514	1.577e-95	319.0	COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,2VIFC@28216|Betaproteobacteria	28216|Betaproteobacteria	S	domain protein	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
CH2_k127_11895776_0	1162668.LFE_0943	1.107e-155	497.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	-	-	-	-	-	-	-	-	-	rve
CH2_k127_11895776_1	270374.MELB17_22520	6.739e-153	496.0	COG5433@1|root,COG5433@2|Bacteria,1MY25@1224|Proteobacteria,1RMRM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase DDE domain group 1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
CH2_k127_12020070_7	1095769.CAHF01000014_gene3091	3.018e-59	209.0	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,2VK0Y@28216|Betaproteobacteria,47326@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
CH2_k127_12020070_8	1163617.SCD_n00099	7.154e-43	164.0	COG2891@1|root,COG2891@2|Bacteria,1RBNF@1224|Proteobacteria,2VQQ3@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Rod shape-determining protein MreD	mreD	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
CH2_k127_12020070_0	1163617.SCD_n00100	1.887e-302	938.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,2VHBZ@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Catalyzes cross-linking of the peptidoglycan cell wall	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
CH2_k127_12020070_1	1163617.SCD_n00101	9.941e-164	525.0	COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,2VH8Q@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Peptidoglycan polymerase that is essential for cell wall elongation	mrdB	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
CH2_k127_12020070_5	1163617.SCD_n00102	1.087e-87	300.0	COG0797@1|root,COG3087@1|root,COG0797@2|Bacteria,COG3087@2|Bacteria,1MZ8S@1224|Proteobacteria,2VJAN@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,SPOR
CH2_k127_12020070_2	1163617.SCD_n00103	1.58e-162	519.0	COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,2VH46@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Belongs to the peptidase S11 family	dacC	-	3.4.16.4	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
CH2_k127_12020070_4	1288494.EBAPG3_23030	1.026e-129	420.0	COG0115@1|root,COG0115@2|Bacteria,1MVAT@1224|Proteobacteria,2VIVK@28216|Betaproteobacteria,3727J@32003|Nitrosomonadales	28216|Betaproteobacteria	EH	PFAM Aminotransferase, class IV	dat	-	2.6.1.21	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	-	R01148,R01582,R02459,R02851,R02924,R05053	RC00006,RC00008,RC00025	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4
CH2_k127_12020070_9	1123487.KB892834_gene2779	3.099e-30	123.0	COG2921@1|root,COG2921@2|Bacteria,1RGV5@1224|Proteobacteria,2VTY5@28216|Betaproteobacteria,2KWZM@206389|Rhodocyclales	206389|Rhodocyclales	S	Belongs to the UPF0250 family	-	-	-	ko:K09158	-	-	-	-	ko00000	-	-	-	DUF493
CH2_k127_12020070_6	1163617.SCD_n00106	1.298e-87	294.0	COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,2VQ1Y@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
CH2_k127_12020070_3	1123392.AQWL01000002_gene2034	5.565e-159	506.0	COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,2VIFE@28216|Betaproteobacteria,1KRBV@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
CH2_k127_12020070_10	1163617.SCD_n01583	1.124e-07	53.0	COG3637@1|root,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OMP_b-brl,OmpA_membrane
CH2_k127_12050533_3	1163617.SCD_n00031	1.511e-39	150.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,2VKKI@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
CH2_k127_12050533_4	1112274.KI911560_gene1497	7.283e-37	143.0	COG4654@1|root,COG4654@2|Bacteria,1N6UN@1224|Proteobacteria,2VW1Y@28216|Betaproteobacteria,2KMZ0@206350|Nitrosomonadales	206350|Nitrosomonadales	C	PFAM cytochrome c, class I	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C,Cytochrome_CBB3
CH2_k127_12050533_0	395494.Galf_0301	1.983e-165	530.0	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,2VH55@28216|Betaproteobacteria,44V9D@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
CH2_k127_12050533_2	1123393.KB891316_gene2122	5.151e-139	447.0	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,2VJAS@28216|Betaproteobacteria,1KT21@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
CH2_k127_12050533_1	640081.Dsui_0628	3.615e-158	506.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,2VH43@28216|Betaproteobacteria,2KU9H@206389|Rhodocyclales	206389|Rhodocyclales	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
CH2_k127_12050533_5	1238425.J07HQW2_01749	5.711e-14	74.0	COG0411@1|root,arCOG00926@2157|Archaea,2Y7GE@28890|Euryarchaeota,241GT@183963|Halobacteria	183963|Halobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
CH2_k127_12143645_0	1163617.SCD_n00194	1.76e-255	788.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,2VHYE@28216|Betaproteobacteria	28216|Betaproteobacteria	E	glutamine synthetase	glnA	GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360	5.4.4.3,6.3.1.2	ko:K01915,ko:K20712	ko00220,ko00250,ko00627,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00627,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253,R06988,R09284	RC00010,RC01754,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
CH2_k127_12143645_3	1163617.SCD_n00195	1.669e-41	158.0	2BWQ4@1|root,32QZV@2|Bacteria,1MZQ9@1224|Proteobacteria,2VSNR@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124
CH2_k127_12143645_2	582744.Msip34_2494	9.208e-142	459.0	COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,2VJN7@28216|Betaproteobacteria,2KKW6@206350|Nitrosomonadales	206350|Nitrosomonadales	T	PFAM ATP-binding region ATPase domain protein	-	-	2.7.13.3	ko:K07708	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4
CH2_k127_12143645_1	582744.Msip34_2495	7.175e-209	653.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,2KM9J@206350|Nitrosomonadales	206350|Nitrosomonadales	T	TIGRFAM nitrogen regulation protein NR(I)	-	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CH2_k127_12173576_13	1278307.KB906981_gene4060	6.902e-09	59.0	COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,1RMEQ@1236|Gammaproteobacteria,2QH7R@267894|Psychromonadaceae	1236|Gammaproteobacteria	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	GO:0003674,GO:0003824,GO:0004076,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	iZ_1308.Z0994	BATS,Radical_SAM
CH2_k127_12173576_10	1163617.SCD_n02667	1.966e-35	138.0	2DPBX@1|root,331FU@2|Bacteria,1NB0X@1224|Proteobacteria,2VX47@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_12173576_6	1163617.SCD_n02668	6.453e-69	241.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,2VSPK@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM Phosphoribosyltransferase	comF	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
CH2_k127_12173576_3	1120999.JONM01000005_gene3915	5.414e-148	486.0	COG0745@1|root,COG2208@1|root,COG0745@2|Bacteria,COG2208@2|Bacteria,1N4K5@1224|Proteobacteria,2VKGP@28216|Betaproteobacteria,2KSCH@206351|Neisseriales	206351|Neisseriales	T	Sigma factor PP2C-like phosphatases	-	-	-	ko:K20977	ko02020,ko02025,map02020,map02025	M00820	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HATPase_c_2,Response_reg,SpoIIE
CH2_k127_12173576_12	640081.Dsui_1714	2.278e-25	108.0	COG1366@1|root,COG1366@2|Bacteria,1MZ5N@1224|Proteobacteria,2VWS3@28216|Betaproteobacteria,2KX88@206389|Rhodocyclales	206389|Rhodocyclales	T	STAS domain	-	-	-	ko:K20978	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001	-	-	-	STAS_2
CH2_k127_12173576_2	261292.Nit79A3_0929	1.716e-161	516.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,2VI13@28216|Betaproteobacteria,372T8@32003|Nitrosomonadales	28216|Betaproteobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
CH2_k127_12173576_5	395494.Galf_1025	1.364e-87	293.0	COG1871@1|root,COG1871@2|Bacteria,1RDDB@1224|Proteobacteria,2VJ1T@28216|Betaproteobacteria,44W6N@713636|Nitrosomonadales	28216|Betaproteobacteria	NT	CheD chemotactic sensory transduction	cheD	-	3.5.1.44	ko:K03411	ko02030,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheD
CH2_k127_12173576_4	1163617.SCD_n01122	7.855e-130	420.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,2VKFS@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	cheR	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
CH2_k127_12173576_0	697282.Mettu_2771	0.0	1101.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1XFKT@135618|Methylococcales	135618|Methylococcales	T	PFAM Chemotaxis methyl-accepting receptor, signalling	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,HAMP,MCPsignal,PAS_3,PAS_8,PAS_9,TarH
CH2_k127_12173576_7	748247.AZKH_2104	8.843e-68	233.0	COG0835@1|root,COG0835@2|Bacteria,1RD1W@1224|Proteobacteria,2VR41@28216|Betaproteobacteria,2KW81@206389|Rhodocyclales	206389|Rhodocyclales	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
CH2_k127_12173576_1	1304883.KI912532_gene181	4.071e-244	774.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2VI5B@28216|Betaproteobacteria,2KVAE@206389|Rhodocyclales	206389|Rhodocyclales	NT	Signal transducing histidine kinase, homodimeric domain	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
CH2_k127_12173576_9	1000565.METUNv1_02607	1.481e-61	213.0	COG0745@1|root,COG0745@2|Bacteria,1RHDD@1224|Proteobacteria,2VSDT@28216|Betaproteobacteria,2KWAN@206389|Rhodocyclales	206389|Rhodocyclales	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
CH2_k127_12173576_8	1304883.KI912532_gene183	9.553e-66	240.0	COG0840@1|root,COG0840@2|Bacteria,1RBQH@1224|Proteobacteria,2VNG3@28216|Betaproteobacteria,2KVTI@206389|Rhodocyclales	206389|Rhodocyclales	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
CH2_k127_12173576_11	292415.Tbd_2485	9.409e-34	130.0	COG2221@1|root,COG2221@2|Bacteria,1MWY5@1224|Proteobacteria,2VPWJ@28216|Betaproteobacteria,1KSCU@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Nitrite and sulphite reductase 4Fe-4S domain	-	-	1.8.99.5	ko:K11180	ko00633,ko00920,ko01100,ko01120,map00633,map00920,map01100,map01120	M00596	R00295,R00861,R08035	RC00065,RC01760	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
CH2_k127_12183624_0	1163617.SCD_n00435	7.569e-189	612.0	COG0515@1|root,COG1639@1|root,COG2203@1|root,COG0515@2|Bacteria,COG1639@2|Bacteria,COG2203@2|Bacteria,1NJC4@1224|Proteobacteria,2VHRZ@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Metal-dependent hydrolase HDOD	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HDOD,Pkinase
CH2_k127_12183624_1	1266925.JHVX01000009_gene63	2.608e-100	329.0	COG0353@1|root,COG0353@2|Bacteria,1MV9Q@1224|Proteobacteria,2VJVJ@28216|Betaproteobacteria,372G5@32003|Nitrosomonadales	28216|Betaproteobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
CH2_k127_12183624_3	1163617.SCD_n01511	2.811e-47	171.0	COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,2VSJ2@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	ybaB	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
CH2_k127_12183624_2	1163617.SCD_n01510	3.315e-49	178.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,2VIE0@28216|Betaproteobacteria	28216|Betaproteobacteria	L	DNA polymerase III is a complex multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3 to 5 exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3,DNA_pol3_tau_5
CH2_k127_12208815_3	1123392.AQWL01000002_gene1745	3.594e-98	330.0	2EFRD@1|root,339HE@2|Bacteria,1NDZX@1224|Proteobacteria,2WDJX@28216|Betaproteobacteria,1KSY3@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_12208815_5	1158146.KB907132_gene64	1.846e-56	204.0	COG2755@1|root,COG2755@2|Bacteria,1RHDZ@1224|Proteobacteria,1S60V@1236|Gammaproteobacteria,1WYHQ@135613|Chromatiales	135613|Chromatiales	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CH2_k127_12208815_1	1163617.SCD_n01934	4.824e-199	631.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,2VH1G@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
CH2_k127_12208815_2	1123393.KB891316_gene1431	2.232e-136	439.0	COG1023@1|root,COG1023@2|Bacteria,1QU14@1224|Proteobacteria,2WH34@28216|Betaproteobacteria,1KSTU@119069|Hydrogenophilales	119069|Hydrogenophilales	G	6-phosphogluconate dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	6PGD,NAD_binding_2
CH2_k127_12208815_0	228410.NE0398	9.844e-243	758.0	COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,2VHS1@28216|Betaproteobacteria,371UY@32003|Nitrosomonadales	28216|Betaproteobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
CH2_k127_12208815_4	1266925.JHVX01000002_gene1008	9.412e-77	263.0	COG0363@1|root,COG0363@2|Bacteria,1R5K6@1224|Proteobacteria,2VRZM@28216|Betaproteobacteria,374P8@32003|Nitrosomonadales	28216|Betaproteobacteria	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	pgl	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
CH2_k127_12208815_6	1163617.SCD_n01927	8.691e-56	196.0	COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,2VHR9@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
CH2_k127_12275468_4	396588.Tgr7_0733	4.817e-69	244.0	COG0451@1|root,COG0451@2|Bacteria,1N8PG@1224|Proteobacteria,1RWCX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	GM	Nad-dependent epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
CH2_k127_12275468_2	713586.KB900536_gene1410	2.591e-128	420.0	COG2141@1|root,COG2141@2|Bacteria,1MX64@1224|Proteobacteria,1SCEP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Luciferase-like monooxygenase	luxA	-	1.14.14.3	ko:K00494	ko02020,ko02024,map02020,map02024	-	R10551	RC00080	ko00000,ko00001,ko01000	-	-	-	Bac_luciferase
CH2_k127_12275468_7	1123392.AQWL01000001_gene1544	1.976e-19	95.0	COG1801@1|root,COG1801@2|Bacteria,1NJGC@1224|Proteobacteria,2WC6P@28216|Betaproteobacteria,1KT62@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_12275468_1	1123392.AQWL01000001_gene1545	1.179e-129	418.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,2VJIA@28216|Betaproteobacteria,1KS0M@119069|Hydrogenophilales	119069|Hydrogenophilales	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
CH2_k127_12275468_0	1163617.SCD_n00576	4.446e-132	426.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,2VI5T@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	ABC-type transport system involved in resistance to organic solvents permease component	ttg2B	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
CH2_k127_12275468_5	1123392.AQWL01000001_gene1547	8.665e-63	219.0	COG1463@1|root,COG1463@2|Bacteria,1NCUG@1224|Proteobacteria,2VRKR@28216|Betaproteobacteria,1KRP2@119069|Hydrogenophilales	119069|Hydrogenophilales	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
CH2_k127_12275468_3	522306.CAP2UW1_0617	7.46e-72	248.0	COG2854@1|root,COG2854@2|Bacteria,1NKFA@1224|Proteobacteria,2VR85@28216|Betaproteobacteria,1KQ2C@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	Q	MlaC protein	ttg2D	-	-	ko:K07323	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	MlaC
CH2_k127_12275468_8	1163617.SCD_n00579	6.966e-19	91.0	COG3113@1|root,COG3113@2|Bacteria	2|Bacteria	S	response to antibiotic	-	-	-	ko:K07122	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	STAS_2
CH2_k127_12275468_6	1266925.JHVX01000001_gene2500	1.5e-22	98.0	COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,2VI81@28216|Betaproteobacteria,3726R@32003|Nitrosomonadales	28216|Betaproteobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	ybhF_1	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CH2_k127_12304749_4	582744.Msip34_0750	7.625e-36	139.0	COG1345@1|root,COG1345@2|Bacteria,1MUVP@1224|Proteobacteria,2VHMK@28216|Betaproteobacteria,2KKHJ@206350|Nitrosomonadales	206350|Nitrosomonadales	N	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	-	-	-	ko:K02407	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_IN,FliD_C,FliD_N
CH2_k127_12304749_2	1163617.SCD_n01647	1.333e-40	155.0	COG1516@1|root,COG1516@2|Bacteria,1MZ3G@1224|Proteobacteria,2VU2S@28216|Betaproteobacteria	28216|Betaproteobacteria	N	Flagellar protein fliS	fliS	-	-	ko:K02422	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliS
CH2_k127_12304749_6	1116472.MGMO_25c00560	1.544e-12	71.0	2E53Z@1|root,32ZWZ@2|Bacteria,1N9EZ@1224|Proteobacteria	1224|Proteobacteria	N	Flagellar protein FliT	fliT	-	-	ko:K02423	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliT
CH2_k127_12304749_5	1163617.SCD_n01644	5.749e-23	102.0	2EQYD@1|root,33II1@2|Bacteria,1NHV5@1224|Proteobacteria,2VXZK@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF2802)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2802
CH2_k127_12304749_1	1163617.SCD_n01643	3.767e-68	248.0	COG3144@1|root,COG3144@2|Bacteria,1N0CE@1224|Proteobacteria,2VQG2@28216|Betaproteobacteria	28216|Betaproteobacteria	N	Flagellar hook-length control protein FliK	fliK1	-	-	-	-	-	-	-	-	-	-	-	Flg_hook
CH2_k127_12304749_3	1163617.SCD_n01642	4.748e-36	138.0	COG2257@1|root,COG2257@2|Bacteria,1N7F1@1224|Proteobacteria,2VTYF@28216|Betaproteobacteria	28216|Betaproteobacteria	N	homolog of the cytoplasmic domain of flagellar protein FhlB	flhB_1	-	-	ko:K04061	-	-	-	-	ko00000,ko02044	-	-	-	Bac_export_2
CH2_k127_12304749_0	1163617.SCD_n01638	3.898e-103	340.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,2VI2G@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,GlnD_UR_UTase,HD,NTP_transf_2
CH2_k127_12350917_1	29581.BW37_04691	1.597e-93	316.0	COG4301@1|root,COG4301@2|Bacteria,1MUCG@1224|Proteobacteria,2VJHK@28216|Betaproteobacteria,473AH@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Histidine-specific methyltransferase, SAM-dependent	egtD	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_33
CH2_k127_12350917_0	1163617.SCD_n01479	0.0	1092.0	COG0466@1|root,COG0466@2|Bacteria,1NTR5@1224|Proteobacteria,2W1SU@28216|Betaproteobacteria	28216|Betaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
CH2_k127_12355101_18	395495.Lcho_0302	2.84e-27	114.0	COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,2VK14@28216|Betaproteobacteria,1KK0K@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
CH2_k127_12355101_16	1163617.SCD_n01763	1.053e-50	185.0	COG0791@1|root,COG0791@2|Bacteria,1N0EE@1224|Proteobacteria,2VSHN@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Nlp p60 protein	-	-	-	ko:K13695,ko:K19303	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
CH2_k127_12355101_14	1163617.SCD_n01605	1.635e-55	202.0	2DN0A@1|root,32UPR@2|Bacteria,1N1BR@1224|Proteobacteria,2VVZG@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_12355101_0	1163617.SCD_n01604	9.425e-254	792.0	COG0341@1|root,COG0661@1|root,COG0341@2|Bacteria,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,2VJ9H@28216|Betaproteobacteria	28216|Betaproteobacteria	U	PFAM ABC-1 domain protein	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,APH
CH2_k127_12355101_15	525897.Dbac_3070	1.022e-54	204.0	COG1450@1|root,COG1450@2|Bacteria,1NC06@1224|Proteobacteria	1224|Proteobacteria	NU	Type ii and iii secretion system protein	-	-	-	-	-	-	-	-	-	-	-	-	Secretin,Secretin_N
CH2_k127_12355101_9	1132855.KB913035_gene935	2.422e-78	266.0	COG3647@1|root,COG3647@2|Bacteria,1N7NB@1224|Proteobacteria,2VRSR@28216|Betaproteobacteria,2KN0E@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Predicted membrane protein (DUF2238)	-	-	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
CH2_k127_12355101_1	1163617.SCD_n01705	9.018e-215	682.0	COG2199@1|root,COG3706@2|Bacteria,1MXAW@1224|Proteobacteria,2VK79@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	2.7.7.65	ko:K13590	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF
CH2_k127_12355101_17	1163617.SCD_n01704	2.447e-42	160.0	COG1815@1|root,COG1815@2|Bacteria,1MZ8P@1224|Proteobacteria,2VUJ4@28216|Betaproteobacteria	28216|Betaproteobacteria	N	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body	flgB	-	-	ko:K02387	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod
CH2_k127_12355101_12	1163617.SCD_n01703	5.037e-58	203.0	COG1558@1|root,COG1558@2|Bacteria,1RHI3@1224|Proteobacteria,2VSK1@28216|Betaproteobacteria	28216|Betaproteobacteria	N	Belongs to the flagella basal body rod proteins family	flgC	-	-	ko:K02388	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
CH2_k127_12355101_13	1163617.SCD_n01702	2.044e-57	207.0	COG1843@1|root,COG1843@2|Bacteria,1MXCG@1224|Proteobacteria,2VSF6@28216|Betaproteobacteria	28216|Betaproteobacteria	N	Required for flagellar hook formation. May act as a scaffolding protein	flgD	-	-	ko:K02389	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FLgD_tudor,FlgD,FlgD_ig
CH2_k127_12355101_4	292415.Tbd_1634	6.425e-146	473.0	COG1749@1|root,COG1749@2|Bacteria,1MU5J@1224|Proteobacteria,2VIV1@28216|Betaproteobacteria,1KRRZ@119069|Hydrogenophilales	119069|Hydrogenophilales	N	Flagellar basal body rod FlgEFG protein C-terminal	-	-	-	ko:K02390	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlaE,Flg_bb_rod,Flg_bbr_C
CH2_k127_12355101_7	1163617.SCD_n01700	9.706e-93	310.0	COG4787@1|root,COG4787@2|Bacteria,1NZWQ@1224|Proteobacteria,2VISC@28216|Betaproteobacteria	28216|Betaproteobacteria	N	Belongs to the flagella basal body rod proteins family	flgF	-	-	ko:K02391	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
CH2_k127_12355101_5	1163617.SCD_n01699	4.693e-128	413.0	COG4786@1|root,COG4786@2|Bacteria,1MVMA@1224|Proteobacteria,2VH7A@28216|Betaproteobacteria	28216|Betaproteobacteria	N	flagellar basal-body rod protein	flgG	-	-	ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
CH2_k127_12355101_11	640081.Dsui_1738	1.259e-68	239.0	COG2063@1|root,COG2063@2|Bacteria,1RDEY@1224|Proteobacteria,2VRIC@28216|Betaproteobacteria,2KWEC@206389|Rhodocyclales	206389|Rhodocyclales	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgH	-	-	ko:K02393	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgH
CH2_k127_12355101_3	1163617.SCD_n01697	1.569e-155	498.0	COG1706@1|root,COG1706@2|Bacteria,1MVKW@1224|Proteobacteria,2VJAZ@28216|Betaproteobacteria	28216|Betaproteobacteria	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgI	-	-	ko:K02394	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgI
CH2_k127_12355101_8	1163617.SCD_n01696	1.011e-82	286.0	COG1705@1|root,COG3951@1|root,COG1705@2|Bacteria,COG3951@2|Bacteria,1MX2W@1224|Proteobacteria,2VH35@28216|Betaproteobacteria	28216|Betaproteobacteria	N	Flagellar rod assembly protein muramidase FlgJ	flgJ	-	-	ko:K02395	-	-	-	-	ko00000,ko02035	-	-	-	Glucosaminidase,Rod-binding
CH2_k127_12355101_2	292415.Tbd_1628	7.545e-156	514.0	COG1256@1|root,COG1256@2|Bacteria,1MV2M@1224|Proteobacteria,2VH02@28216|Betaproteobacteria,1KRD4@119069|Hydrogenophilales	119069|Hydrogenophilales	N	Flagellar basal body rod FlgEFG protein C-terminal	-	-	-	ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
CH2_k127_12355101_6	261292.Nit79A3_2210	4.04e-105	357.0	COG1344@1|root,COG1344@2|Bacteria,1PJUJ@1224|Proteobacteria,2VM4I@28216|Betaproteobacteria,371W9@32003|Nitrosomonadales	28216|Betaproteobacteria	N	Bacterial flagellin N-terminal helical region	flgL	-	-	ko:K02397	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
CH2_k127_12355101_10	637390.AFOH01000056_gene1573	9.511e-74	249.0	COG1396@1|root,COG1396@2|Bacteria,1QVJF@1224|Proteobacteria,1T2EB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Antitoxin component of bacterial toxin-antitoxin system, MqsA	-	-	-	ko:K13655	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	MqsA_antitoxin
CH2_k127_12365152_5	1163617.SCD_n02749	1.756e-10	69.0	COG2982@1|root,COG2982@2|Bacteria,1QZY2@1224|Proteobacteria,2VTEI@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Protein involved in outer membrane biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_12365152_3	1163617.SCD_n01454	9.63e-46	176.0	COG3827@1|root,COG3827@2|Bacteria,1RGYW@1224|Proteobacteria,2VSW1@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_12365152_4	1163617.SCD_n00441	9.004e-17	81.0	COG2900@1|root,COG2900@2|Bacteria,1NGFM@1224|Proteobacteria,2VXFA@28216|Betaproteobacteria	28216|Betaproteobacteria	S	SlyX	-	-	-	ko:K03745	-	-	-	-	ko00000	-	-	-	SlyX
CH2_k127_12365152_1	1163617.SCD_n01366	3.312e-69	239.0	2CB73@1|root,32RST@2|Bacteria,1MZWF@1224|Proteobacteria,2VV2C@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_12365152_2	517433.PanABDRAFT_3933	8.509e-58	209.0	COG0662@1|root,COG0662@2|Bacteria,1RHRM@1224|Proteobacteria,1S2VE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FdtA
CH2_k127_12365152_0	1163617.SCD_n01384	1.635e-110	359.0	COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,2VH8W@28216|Betaproteobacteria	28216|Betaproteobacteria	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
CH2_k127_12412973_9	1341181.FLJC2902T_14420	4.059e-32	133.0	COG0500@1|root,COG2226@2|Bacteria,4NIN6@976|Bacteroidetes,1IMVG@117743|Flavobacteriia,2NV8X@237|Flavobacterium	976|Bacteroidetes	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Ubie_methyltran
CH2_k127_12412973_5	1163617.SCD_n00832	3.78e-72	251.0	COG0845@1|root,COG0845@2|Bacteria,1R9JJ@1224|Proteobacteria,2W4AP@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2
CH2_k127_12412973_1	1163617.SCD_n00831	1.548e-144	470.0	COG1538@1|root,COG1538@2|Bacteria,1RDNB@1224|Proteobacteria,2W1FP@28216|Betaproteobacteria	28216|Betaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
CH2_k127_12412973_6	1163617.SCD_n00830	9.957e-64	222.0	COG2143@1|root,COG2143@2|Bacteria,1RB3S@1224|Proteobacteria,2VX2X@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Thioredoxin-like	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	Thioredoxin_2
CH2_k127_12412973_7	1123392.AQWL01000001_gene1360	9.244e-59	208.0	COG0526@1|root,COG0526@2|Bacteria,1RKKW@1224|Proteobacteria,2WEVJ@28216|Betaproteobacteria	28216|Betaproteobacteria	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CH2_k127_12412973_0	292415.Tbd_2119	5.026e-228	713.0	COG1027@1|root,COG1027@2|Bacteria,1R9JY@1224|Proteobacteria,2W02M@28216|Betaproteobacteria,1KRC5@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Fumarase C C-terminus	-	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	-	FumaraseC_C,Lyase_1
CH2_k127_12412973_10	395494.Galf_1434	0.0005064	46.0	COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,2VIAA@28216|Betaproteobacteria,44W4P@713636|Nitrosomonadales	28216|Betaproteobacteria	M	TIGRFAM type I secretion membrane fusion protein, HlyD family	-	-	-	ko:K02022	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD,HlyD_3
CH2_k127_12412973_2	1163617.SCD_n00828	3.77e-144	474.0	2C2C7@1|root,2Z85G@2|Bacteria,1PD07@1224|Proteobacteria,2VSBD@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_12412973_4	1163617.SCD_n00827	1.164e-119	397.0	COG1295@1|root,COG1959@1|root,COG1295@2|Bacteria,COG1959@2|Bacteria,1QICW@1224|Proteobacteria,2VJNM@28216|Betaproteobacteria	28216|Betaproteobacteria	K	UPF0761 membrane protein	rbn	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
CH2_k127_12412973_8	1163617.SCD_n00825	1.097e-36	142.0	COG3308@1|root,COG3308@2|Bacteria,1N1EF@1224|Proteobacteria,2VU3C@28216|Betaproteobacteria	28216|Betaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2069
CH2_k127_12412973_3	1163617.SCD_n02060	3.898e-133	439.0	COG0543@1|root,COG1018@1|root,COG0543@2|Bacteria,COG1018@2|Bacteria,1MV72@1224|Proteobacteria	1224|Proteobacteria	C	oxidoreductase FAD NAD(P)-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,Fer2
CH2_k127_12488642_0	1163617.SCD_n02177	1.471e-173	548.0	COG5265@1|root,COG5265@2|Bacteria,1NSKS@1224|Proteobacteria,2WGG3@28216|Betaproteobacteria	28216|Betaproteobacteria	V	Abc transporter	atm1	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CH2_k127_12488642_2	179408.Osc7112_1153	3.633e-86	290.0	COG0625@1|root,COG0625@2|Bacteria,1G4IV@1117|Cyanobacteria,1HAH4@1150|Oscillatoriales	1117|Cyanobacteria	O	Glutathione S-transferase, C-terminal domain	GSTO1	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	DUF952,GST_C_2,GST_N_3
CH2_k127_12488642_3	395494.Galf_1123	8.808e-36	136.0	COG3530@1|root,COG3530@2|Bacteria,1N7GT@1224|Proteobacteria,2VW2G@28216|Betaproteobacteria,44W2F@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Putative quorum-sensing-regulated virulence factor	-	-	-	ko:K09954	-	-	-	-	ko00000	-	-	-	QSregVF_b
CH2_k127_12488642_1	697282.Mettu_0390	9.739e-104	345.0	COG2234@1|root,COG2234@2|Bacteria,1MXZS@1224|Proteobacteria,1S0QR@1236|Gammaproteobacteria,1XFU4@135618|Methylococcales	135618|Methylococcales	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
CH2_k127_12541129_2	261292.Nit79A3_2535	1.634e-158	501.0	COG0589@1|root,COG0589@2|Bacteria,1PUQK@1224|Proteobacteria,2VT3N@28216|Betaproteobacteria	28216|Betaproteobacteria	T	universal stress protein	uspE	-	-	-	-	-	-	-	-	-	-	-	Usp
CH2_k127_12541129_7	425104.Ssed_1390	2.627e-25	111.0	COG1863@1|root,COG1863@2|Bacteria,1N7MB@1224|Proteobacteria,1SCQX@1236|Gammaproteobacteria,2QDMI@267890|Shewanellaceae	1236|Gammaproteobacteria	P	Na+/H+ ion antiporter subunit	-	-	-	ko:K05569	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MNHE
CH2_k127_12541129_9	472759.Nhal_1820	4.762e-18	87.0	COG2212@1|root,COG2212@2|Bacteria,1N90U@1224|Proteobacteria,1SCXI@1236|Gammaproteobacteria,1WZ9H@135613|Chromatiales	135613|Chromatiales	P	Multiple resistance and pH regulation protein F	-	-	-	ko:K05570	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	MrpF_PhaF
CH2_k127_12541129_5	1255043.TVNIR_0097	3.637e-30	123.0	COG1320@1|root,COG1320@2|Bacteria,1N75I@1224|Proteobacteria,1SCHB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	PFAM Na H antiporter subunit	-	-	-	ko:K05571	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	PhaG_MnhG_YufB
CH2_k127_12541129_8	1255043.TVNIR_0096	1.187e-21	99.0	COG1563@1|root,COG1563@2|Bacteria,1N7YY@1224|Proteobacteria	1224|Proteobacteria	P	Domain of unknown function (DUF4040)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4040
CH2_k127_12541129_4	1255043.TVNIR_0095	9.846e-42	166.0	COG2111@1|root,COG2111@2|Bacteria,1QVK4@1224|Proteobacteria,1T54T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Domain related to MnhB subunit of Na+/H+ antiporter	-	-	-	-	-	-	-	-	-	-	-	-	MnhB
CH2_k127_12541129_6	1479237.JMLY01000001_gene3482	2.262e-28	117.0	COG1006@1|root,COG1006@2|Bacteria,1N7TX@1224|Proteobacteria,1SD0U@1236|Gammaproteobacteria,4698T@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	NADH-ubiquinone/plastoquinone oxidoreductase chain 4L	-	-	-	ko:K05567	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Oxidored_q2
CH2_k127_12541129_3	1123368.AUIS01000004_gene136	1.718e-144	473.0	COG0651@1|root,COG0651@2|Bacteria,1MURB@1224|Proteobacteria,1RYB4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	CP	Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter MnhD subunit	-	-	-	-	-	-	-	-	-	-	-	-	Proton_antipo_M,Proton_antipo_N
CH2_k127_12541129_1	1123368.AUIS01000004_gene137	1.28e-201	642.0	COG0651@1|root,COG0651@2|Bacteria,1QU5Z@1224|Proteobacteria,1T20X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	CP	PFAM NADH Ubiquinone plastoquinone (complex I)	-	-	-	ko:K05568	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M,Proton_antipo_N
CH2_k127_12541129_0	1158292.JPOE01000005_gene388	0.0	1292.0	COG1061@1|root,COG4951@1|root,COG1061@2|Bacteria,COG4951@2|Bacteria,1QU9I@1224|Proteobacteria,2VHI0@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Type III restriction	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,ResIII
CH2_k127_1259047_1	1163617.SCD_n01315	5.715e-265	822.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	type II secretion system protein E	gspE	-	-	ko:K02454,ko:K02652,ko:K12276	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
CH2_k127_1259047_0	1163617.SCD_n01314	5.452e-302	938.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,2VI7X@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	general secretion pathway protein D	gspD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
CH2_k127_1259047_2	1163617.SCD_n01313	9.832e-60	216.0	COG3031@1|root,COG3031@2|Bacteria	2|Bacteria	U	protein transport across the cell outer membrane	gspC	-	-	ko:K02452,ko:K02463	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	PDZ_2,T2SSC
CH2_k127_1259047_3	1125971.ASJB01000080_gene7213	9.795e-21	102.0	COG1404@1|root,COG1472@1|root,COG3828@1|root,COG4932@1|root,COG1404@2|Bacteria,COG1472@2|Bacteria,COG3828@2|Bacteria,COG4932@2|Bacteria,2I4SB@201174|Actinobacteria,4EE04@85010|Pseudonocardiales	201174|Actinobacteria	GMO	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,PKD,Peptidase_S8,Ricin_B_lectin
CH2_k127_12640268_2	1158292.JPOE01000002_gene2916	4.067e-72	252.0	COG1340@1|root,COG1340@2|Bacteria,1R1VF@1224|Proteobacteria,2WI5X@28216|Betaproteobacteria,1KMQ2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Ion transport protein	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
CH2_k127_12640268_0	580332.Slit_0650	4.503e-232	722.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,2VJ4F@28216|Betaproteobacteria,44V8Z@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
CH2_k127_12640268_1	1163617.SCD_n00838	5.587e-75	255.0	COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,2VR9P@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
CH2_k127_12640268_3	522306.CAP2UW1_1500	1.244e-08	55.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,2VI9P@28216|Betaproteobacteria,1KPPY@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
CH2_k127_12652496_1	1163617.SCD_n02207	1.868e-142	456.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,2VHZG@28216|Betaproteobacteria	28216|Betaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
CH2_k127_12652496_0	1163617.SCD_n02208	3.626e-291	904.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,2VHKD@28216|Betaproteobacteria	28216|Betaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD-TM1,SecD_SecF,Sec_GG
CH2_k127_12652496_3	582744.Msip34_1995	2.71e-20	91.0	COG3197@1|root,COG3197@2|Bacteria,1PJS9@1224|Proteobacteria,2W85G@28216|Betaproteobacteria,2KNZZ@206350|Nitrosomonadales	206350|Nitrosomonadales	P	Cytochrome oxidase maturation protein cbb3-type	-	-	-	-	-	-	-	-	-	-	-	-	FixS
CH2_k127_12652496_2	1236959.BAMT01000004_gene805	5.745e-96	323.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2VJSM@28216|Betaproteobacteria,2KM5C@206350|Nitrosomonadales	206350|Nitrosomonadales	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
CH2_k127_12712472_2	582744.Msip34_0037	8.302e-37	140.0	COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,2VH47@28216|Betaproteobacteria,2KMF6@206350|Nitrosomonadales	206350|Nitrosomonadales	E	TIGRFAM argininosuccinate lyase	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
CH2_k127_12712472_1	1123393.KB891330_gene907	1.961e-59	211.0	COG1846@1|root,COG1846@2|Bacteria,1MZS9@1224|Proteobacteria,2WFXE@28216|Betaproteobacteria,1KSXG@119069|Hydrogenophilales	119069|Hydrogenophilales	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
CH2_k127_12712472_3	1123367.C666_08620	2.149e-31	125.0	COG1965@1|root,COG1965@2|Bacteria,1RH9A@1224|Proteobacteria,2VVS3@28216|Betaproteobacteria,2KWZ7@206389|Rhodocyclales	206389|Rhodocyclales	P	Belongs to the frataxin	cyaY	-	-	ko:K06202	-	-	-	-	ko00000	-	-	-	Frataxin_Cyay
CH2_k127_12712472_0	580332.Slit_0475	6.301e-88	297.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,2VI3M@28216|Betaproteobacteria,44VK2@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
CH2_k127_12746756_0	1123393.KB891326_gene66	9.361e-246	765.0	COG0189@1|root,COG0189@2|Bacteria,1MX5X@1224|Proteobacteria,2VJP0@28216|Betaproteobacteria,1KS9Q@119069|Hydrogenophilales	119069|Hydrogenophilales	HJ	RimK-like ATPgrasp N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RLAN
CH2_k127_12746756_2	1123393.KB891326_gene65	6.149e-178	565.0	COG2170@1|root,COG2170@2|Bacteria,1MY35@1224|Proteobacteria,2VNEE@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Glutamate-cysteine ligase family 2(GCS2)	-	-	-	-	-	-	-	-	-	-	-	-	GCS2
CH2_k127_12746756_3	1123393.KB891326_gene64	7.067e-98	329.0	COG3931@1|root,COG3931@2|Bacteria,1PWF0@1224|Proteobacteria,2VZYZ@28216|Betaproteobacteria,1KSK2@119069|Hydrogenophilales	119069|Hydrogenophilales	E	N-formylglutamate amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FGase
CH2_k127_12746756_4	375286.mma_3683	2.157e-25	109.0	2CKHZ@1|root,332B5@2|Bacteria,1NAZ6@1224|Proteobacteria,2VW0U@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_12746756_1	1163617.SCD_n01401	2.047e-217	684.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Belongs to the DEAD box helicase family	rhlE	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
CH2_k127_12746756_5	1163617.SCD_n01673	2.602e-06	49.0	2EJ60@1|root,33CX7@2|Bacteria,1NJ7I@1224|Proteobacteria	1224|Proteobacteria	S	Atypical PilZ domain, cyclic di-GMP receptor	-	-	-	-	-	-	-	-	-	-	-	-	PilZ_2
CH2_k127_12764609_1	243233.MCA2402	3.153e-37	145.0	COG3448@1|root,COG3448@2|Bacteria,1MXJG@1224|Proteobacteria,1RYFC@1236|Gammaproteobacteria,1XEYX@135618|Methylococcales	135618|Methylococcales	T	HPP family	-	-	-	ko:K07168	-	-	-	-	ko00000	-	-	-	CBS,HPP
CH2_k127_12764609_2	349521.HCH_04142	3.934e-37	150.0	COG0745@1|root,COG2198@1|root,COG0745@2|Bacteria,COG2198@2|Bacteria,1NMCM@1224|Proteobacteria,1SPAU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	Hpt
CH2_k127_12764609_0	523791.Kkor_1049	1.471e-117	383.0	COG1049@1|root,COG1049@2|Bacteria,1MVCR@1224|Proteobacteria,1RNMC@1236|Gammaproteobacteria,1XI21@135619|Oceanospirillales	135619|Oceanospirillales	C	Belongs to the aconitase IPM isomerase family	acnB	-	4.2.1.3,4.2.1.99	ko:K01682	ko00020,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173	R01324,R01325,R01900,R04425	RC00497,RC00498,RC00618,RC01153	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_2_N,Aconitase_B_N
CH2_k127_12772563_4	1163617.SCD_n02695	1.908e-155	495.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VI3F@28216|Betaproteobacteria	28216|Betaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
CH2_k127_12772563_10	1163617.SCD_n02696	8.501e-130	422.0	COG0845@1|root,COG0845@2|Bacteria,1NQZ0@1224|Proteobacteria,2VJAC@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_D23
CH2_k127_12772563_5	1132855.KB913035_gene2443	7.998e-154	491.0	COG3547@1|root,COG3547@2|Bacteria,1MXKJ@1224|Proteobacteria,2VP05@28216|Betaproteobacteria,2KP6E@206350|Nitrosomonadales	28216|Betaproteobacteria	L	Transposase	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
CH2_k127_12772563_16	292415.Tbd_2395	4.399e-54	192.0	COG0640@1|root,COG0640@2|Bacteria,1N72Q@1224|Proteobacteria,2VU9V@28216|Betaproteobacteria,1KT6W@119069|Hydrogenophilales	119069|Hydrogenophilales	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
CH2_k127_12772563_1	1163617.SCD_n02698	3.339e-256	797.0	COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,2VMTN@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
CH2_k127_12772563_11	1163617.SCD_n02699	3.416e-117	390.0	COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,2VIV9@28216|Betaproteobacteria	28216|Betaproteobacteria	D	peptidase	envC	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CH2_k127_12772563_2	1163617.SCD_n02700	4.916e-227	711.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,2VJ86@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
CH2_k127_12772563_18	292415.Tbd_2391	1.236e-35	139.0	2BG6F@1|root,32A39@2|Bacteria,1RI4Y@1224|Proteobacteria,2VT9E@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_12772563_12	1163617.SCD_n02701	9.97e-114	371.0	COG0476@1|root,COG0476@2|Bacteria,1MW7H@1224|Proteobacteria,2VI1U@28216|Betaproteobacteria	28216|Betaproteobacteria	H	PFAM UBA THIF-type NAD FAD binding protein	thiF	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
CH2_k127_12772563_21	765911.Thivi_2625	2.003e-19	96.0	2EG86@1|root,33A00@2|Bacteria,1NGSH@1224|Proteobacteria	1224|Proteobacteria	S	PEP-CTERM motif	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
CH2_k127_12772563_13	1163617.SCD_n02703	3.088e-89	297.0	COG1309@1|root,COG1309@2|Bacteria,1MWF7@1224|Proteobacteria,2VQ4C@28216|Betaproteobacteria	28216|Betaproteobacteria	K	PFAM regulatory protein TetR	slmA	-	-	ko:K05501	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	TetR_N
CH2_k127_12772563_3	1163617.SCD_n00329	2.435e-158	503.0	COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,2VIIY@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
CH2_k127_12772563_15	1123393.KB891316_gene1605	2.06e-54	194.0	COG0071@1|root,COG0071@2|Bacteria,1N1RF@1224|Proteobacteria,2VT18@28216|Betaproteobacteria,1KT32@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Hsp20/alpha crystallin family	-	-	-	-	-	-	-	-	-	-	-	-	HSP20
CH2_k127_12772563_14	640081.Dsui_1180	7.589e-70	244.0	COG4567@1|root,COG4567@2|Bacteria,1RD7J@1224|Proteobacteria,2VN1I@28216|Betaproteobacteria,2KWU2@206389|Rhodocyclales	206389|Rhodocyclales	T	COG4567 Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain	-	-	-	ko:K15012	ko02020,map02020	M00523	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg
CH2_k127_12772563_9	1288494.EBAPG3_7890	8.167e-132	434.0	COG4191@1|root,COG4191@2|Bacteria,1MWR3@1224|Proteobacteria,2VNY1@28216|Betaproteobacteria,372C3@32003|Nitrosomonadales	28216|Betaproteobacteria	T	Signal transduction histidine kinase	regB	-	2.7.13.3	ko:K15011	ko02020,map02020	M00523	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
CH2_k127_12772563_0	159087.Daro_4090	1.677e-287	899.0	COG4206@1|root,COG4206@2|Bacteria,1QUGQ@1224|Proteobacteria,2VIRV@28216|Betaproteobacteria,2KVA3@206389|Rhodocyclales	206389|Rhodocyclales	H	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
CH2_k127_12772563_6	1163617.SCD_n02548	3.435e-144	468.0	COG4409@1|root,COG4409@2|Bacteria,1MVUD@1224|Proteobacteria,2VIYQ@28216|Betaproteobacteria	28216|Betaproteobacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR,BNR_2
CH2_k127_12772563_17	1163617.SCD_n02547	9.051e-46	171.0	COG0526@1|root,COG0526@2|Bacteria,1MZ9B@1224|Proteobacteria,2VV4Z@28216|Betaproteobacteria	28216|Betaproteobacteria	CO	COG0526 Thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CH2_k127_12772563_19	1163617.SCD_n02542	1.706e-34	140.0	COG0810@1|root,COG0810@2|Bacteria,1MZPX@1224|Proteobacteria,2VM32@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	tonB	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
CH2_k127_12772563_20	522306.CAP2UW1_1795	3.07e-33	133.0	COG2847@1|root,COG2847@2|Bacteria,1MZ3M@1224|Proteobacteria,2VTY7@28216|Betaproteobacteria,1KR0V@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	Copper chaperone PCu(A)C	-	-	-	ko:K09796	-	-	-	-	ko00000,ko03110	-	-	-	DUF1775,PCuAC
CH2_k127_12772563_8	748280.NH8B_1162	8.95e-135	434.0	2EYIJ@1|root,33RSC@2|Bacteria,1NQWX@1224|Proteobacteria,2W032@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_12772563_7	1163617.SCD_n01369	4.786e-141	452.0	COG0500@1|root,COG2226@2|Bacteria,1MXP4@1224|Proteobacteria,2VJM3@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Methyltransferase	ubiE_1	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
CH2_k127_12772563_22	1297569.MESS2_1540016	1.297e-07	59.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CH2_k127_12784983_4	1163617.SCD_n00005	1.358e-124	404.0	COG0550@1|root,COG0551@1|root,COG0550@2|Bacteria,COG0551@2|Bacteria,1MUFZ@1224|Proteobacteria,2VHUF@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
CH2_k127_12784983_7	1163617.SCD_n00006	2.699e-42	159.0	COG2922@1|root,COG2922@2|Bacteria,1RD5F@1224|Proteobacteria,2VRJF@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Belongs to the Smg family	smg	-	-	ko:K03747	-	-	-	-	ko00000	-	-	-	DUF494
CH2_k127_12784983_1	1163617.SCD_n00007	1.297e-141	459.0	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,2VH3W@28216|Betaproteobacteria	28216|Betaproteobacteria	LU	DNA protecting protein DprA	smf	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
CH2_k127_12784983_3	1163617.SCD_n00008	7.19e-135	437.0	COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,2VIZJ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM Peptidoglycan-binding LysM	-	-	-	-	-	-	-	-	-	-	-	-	LysM
CH2_k127_12784983_6	1163617.SCD_n00009	1.129e-71	245.0	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,2VQ4N@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
CH2_k127_12784983_5	1163617.SCD_n00010	8.099e-117	383.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,2VIS2@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
CH2_k127_12784983_2	640081.Dsui_0815	1.245e-136	439.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,2VIVB@28216|Betaproteobacteria,2KUBC@206389|Rhodocyclales	206389|Rhodocyclales	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
CH2_k127_12784983_0	1163617.SCD_n00011	1.091e-142	461.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1MWPE@1224|Proteobacteria,2VI4V@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	sun	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
CH2_k127_12809585_2	1163617.SCD_n01250	8.025e-70	239.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,2VIXG@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Inositol monophosphatase	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
CH2_k127_12809585_1	1163617.SCD_n01251	2.994e-83	283.0	COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,2VI2D@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA	trmJ	-	-	ko:K02533	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
CH2_k127_12809585_0	1163617.SCD_n01252	4.646e-127	409.0	COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,2VH8C@28216|Betaproteobacteria	28216|Betaproteobacteria	E	serine O-acetyltransferase	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
CH2_k127_12809585_3	1163617.SCD_n01253	1.262e-67	233.0	COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,2VRGK@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Iron-sulfur cluster assembly transcription factor IscR	iscR	-	-	ko:K13643	-	-	-	-	ko00000,ko03000	-	-	-	Rrf2
CH2_k127_12809585_4	1304883.KI912532_gene2397	8.798e-46	166.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,2VH91@28216|Betaproteobacteria,2KUBJ@206389|Rhodocyclales	206389|Rhodocyclales	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
CH2_k127_12842427_7	1163617.SCD_n01779	1.74e-42	157.0	COG1028@1|root,COG1028@2|Bacteria,1MWBC@1224|Proteobacteria,2VMWZ@28216|Betaproteobacteria	28216|Betaproteobacteria	IQ	dehydrogenase reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CH2_k127_12842427_4	1163617.SCD_n01780	4.219e-70	245.0	COG1716@1|root,COG1716@2|Bacteria,1MW1M@1224|Proteobacteria,2W3G9@28216|Betaproteobacteria	28216|Betaproteobacteria	T	FHA domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
CH2_k127_12842427_3	1163617.SCD_n01781	7.38e-91	306.0	COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,2VM6F@28216|Betaproteobacteria	28216|Betaproteobacteria	T	protein phosphatase 2C domain protein	pppL	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
CH2_k127_12842427_2	1163617.SCD_n01782	1.037e-132	439.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria	28216|Betaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
CH2_k127_12842427_6	1163617.SCD_n01783	6.272e-51	183.0	COG3063@1|root,COG3063@2|Bacteria,1N7DT@1224|Proteobacteria,2VW37@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	Type IV pilus biogenesis stability protein PilW	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_12842427_5	1348657.M622_04115	5.857e-61	219.0	COG1716@1|root,COG1716@2|Bacteria,1MW1M@1224|Proteobacteria,2VJ1K@28216|Betaproteobacteria,2KUV6@206389|Rhodocyclales	206389|Rhodocyclales	T	(FHA) domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
CH2_k127_12842427_0	1163617.SCD_n01785	7.269e-248	770.0	COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,2VH93@28216|Betaproteobacteria	28216|Betaproteobacteria	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
CH2_k127_12842427_1	1163617.SCD_n01786	1.427e-145	469.0	COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,2VIXM@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
CH2_k127_12842427_8	323848.Nmul_A1947	4.515e-18	83.0	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,2VIKN@28216|Betaproteobacteria,372T4@32003|Nitrosomonadales	28216|Betaproteobacteria	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
CH2_k127_12903007_2	1163617.SCD_n03020	4.225e-176	553.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,2VHDZ@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
CH2_k127_12903007_4	395494.Galf_2932	1.815e-59	208.0	COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,2VR2R@28216|Betaproteobacteria,44VV1@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
CH2_k127_12903007_1	1123393.KB891332_gene2807	1.353e-203	643.0	COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,2VH54@28216|Betaproteobacteria,1KS90@119069|Hydrogenophilales	119069|Hydrogenophilales	M	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3
CH2_k127_12903007_0	713586.KB900536_gene2120	2.377e-318	983.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,1RMVN@1236|Gammaproteobacteria,1WW41@135613|Chromatiales	135613|Chromatiales	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
CH2_k127_12903007_3	1163617.SCD_n03016	3.511e-87	291.0	COG1192@1|root,COG1192@2|Bacteria,1N3GB@1224|Proteobacteria,2VSGK@28216|Betaproteobacteria	28216|Betaproteobacteria	D	Cobyrinic acid ac-diamide synthase	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
CH2_k127_12927359_5	1123393.KB891328_gene636	7.29e-24	102.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,2VIGA@28216|Betaproteobacteria,1KRFP@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
CH2_k127_12927359_3	1163617.SCD_n01807	3.262e-81	276.0	COG2976@1|root,COG2976@2|Bacteria,1N117@1224|Proteobacteria,2VSHE@28216|Betaproteobacteria	28216|Betaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TPR_21
CH2_k127_12927359_2	1163617.SCD_n01806	1.399e-145	469.0	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,2VHH5@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamB	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
CH2_k127_12927359_0	1163617.SCD_n01805	6.374e-225	704.0	COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,2VI8D@28216|Betaproteobacteria	28216|Betaproteobacteria	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
CH2_k127_12927359_4	243365.CV_3533	6.169e-37	141.0	COG1923@1|root,COG1923@2|Bacteria,1MZM1@1224|Proteobacteria,2VTXK@28216|Betaproteobacteria,2KRCS@206351|Neisseriales	206351|Neisseriales	J	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs	hfq	-	-	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	-	-	-	ko00000,ko00001,ko03019,ko03036	-	-	-	Hfq
CH2_k127_12927359_1	1163617.SCD_n01801	1.303e-147	471.0	COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,2VI86@28216|Betaproteobacteria	28216|Betaproteobacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
CH2_k127_12948442_2	1123392.AQWL01000005_gene3099	1.16e-105	349.0	COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria,2VIBZ@28216|Betaproteobacteria,1KSKP@119069|Hydrogenophilales	119069|Hydrogenophilales	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
CH2_k127_12948442_0	1163617.SCD_n00396	2.007e-229	727.0	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,2VHPK@28216|Betaproteobacteria	28216|Betaproteobacteria	M	transglycosylase	slt	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,SLT_L
CH2_k127_12948442_1	1288494.EBAPG3_27680	7.723e-204	643.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2VJQT@28216|Betaproteobacteria,372AX@32003|Nitrosomonadales	28216|Betaproteobacteria	C	Aldehyde dehydrogenase family	sad	-	1.2.1.16,1.2.1.20,1.2.1.24,1.2.1.79	ko:K00135,ko:K08324	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CH2_k127_1301979_5	1366050.N234_19355	1.807e-38	147.0	COG0755@1|root,COG0755@2|Bacteria,1RG6M@1224|Proteobacteria,2VI4N@28216|Betaproteobacteria,1K2Y8@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Pfam Cytochrome C assembly protein	ccsB	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
CH2_k127_1301979_0	1123392.AQWL01000002_gene1940	2.938e-240	760.0	COG1333@1|root,COG1333@2|Bacteria,1N6XE@1224|Proteobacteria,2VJK9@28216|Betaproteobacteria,1KSG4@119069|Hydrogenophilales	119069|Hydrogenophilales	O	ResB-like family	-	-	-	-	-	-	-	-	-	-	-	-	ResB
CH2_k127_1301979_4	1163617.SCD_n02935	4.761e-66	232.0	COG2863@1|root,COG2863@2|Bacteria,1N2NB@1224|Proteobacteria,2VQNZ@28216|Betaproteobacteria	28216|Betaproteobacteria	C	PFAM Cytochrome c, class I	cyc	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
CH2_k127_1301979_2	1485544.JQKP01000012_gene2123	1.878e-81	276.0	COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,2VIKF@28216|Betaproteobacteria,44V31@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
CH2_k127_1301979_1	1163617.SCD_n02937	3.138e-176	557.0	COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,2VHC6@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Belongs to the ALAD family	hemB	GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
CH2_k127_1301979_3	1163617.SCD_n02938	3.334e-69	241.0	COG5581@1|root,COG5581@2|Bacteria,1MX00@1224|Proteobacteria,2VQEK@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility	ycgR	-	-	-	-	-	-	-	-	-	-	-	PilZ,YcgR
CH2_k127_1324819_4	666681.M301_2509	5.141e-22	97.0	COG3064@1|root,COG3064@2|Bacteria,1RKZU@1224|Proteobacteria,2WGP5@28216|Betaproteobacteria,2KMSA@206350|Nitrosomonadales	206350|Nitrosomonadales	M	TIGRFAM protein TolA	-	-	-	ko:K03646	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	TonB_2
CH2_k127_1324819_0	1163617.SCD_n00676	4.758e-191	605.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,2VH9R@28216|Betaproteobacteria	28216|Betaproteobacteria	U	Involved in the tonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
CH2_k127_1324819_3	1163617.SCD_n00677	7.791e-69	237.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,2VSP6@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Belongs to the ompA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
CH2_k127_1324819_2	1163617.SCD_n00678	1.055e-71	251.0	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,2VIPC@28216|Betaproteobacteria	28216|Betaproteobacteria	D	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TolA_bind_tri,YfiO
CH2_k127_1324819_1	1163617.SCD_n00679	5.024e-101	332.0	COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,2VGZ7@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008144,GO:0016829,GO:0016840,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:1901681,GO:1904047	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
CH2_k127_1324819_5	159087.Daro_4042	2.352e-11	66.0	COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,2VHY3@28216|Betaproteobacteria,2KVAA@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
CH2_k127_1338668_0	228410.NE1013	6.572e-87	290.0	COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,2VJAP@28216|Betaproteobacteria,372K7@32003|Nitrosomonadales	28216|Betaproteobacteria	C	cytochrome c oxidase, subunit III	coxC	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
CH2_k127_1338668_2	658187.LDG_8454	2.72e-15	81.0	2EGIJ@1|root,33AAQ@2|Bacteria,1NH9B@1224|Proteobacteria,1SGKJ@1236|Gammaproteobacteria,1JFAY@118969|Legionellales	118969|Legionellales	S	Protein of unknown function (DUF2909)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2909
CH2_k127_1338668_1	1335757.SPICUR_01605	7.937e-32	131.0	COG3346@1|root,COG3346@2|Bacteria,1MZUH@1224|Proteobacteria,1S8S0@1236|Gammaproteobacteria,1WYUV@135613|Chromatiales	135613|Chromatiales	S	SURF1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	SURF1
CH2_k127_1415755_4	1163617.SCD_n00318	4.728e-14	78.0	COG1366@1|root,COG1366@2|Bacteria,1R08G@1224|Proteobacteria,2VIGK@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	-	-	-	-	-	-	-	-	-	STAS_2
CH2_k127_1415755_1	580332.Slit_0146	1.269e-123	402.0	COG4973@1|root,COG4973@2|Bacteria,1MUJJ@1224|Proteobacteria,2VJ5V@28216|Betaproteobacteria,44VAD@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Phage integrase, N-terminal SAM-like domain	xerC	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
CH2_k127_1415755_2	1163617.SCD_n00312	2.671e-76	261.0	COG3159@1|root,COG3159@2|Bacteria,1R4BP@1224|Proteobacteria,2VPN6@28216|Betaproteobacteria	28216|Betaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09921	-	-	-	-	ko00000	-	-	-	DUF484
CH2_k127_1415755_0	1163617.SCD_n00311	5.695e-135	434.0	COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,2VI0C@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
CH2_k127_1415755_3	1163617.SCD_n00310	3.794e-33	129.0	COG1832@1|root,COG1832@2|Bacteria,1N03D@1224|Proteobacteria,2VU9G@28216|Betaproteobacteria	28216|Betaproteobacteria	S	coa-binding	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
CH2_k127_141891_4	765911.Thivi_3679	1.339e-68	237.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,1RS5D@1236|Gammaproteobacteria,1WXTX@135613|Chromatiales	135613|Chromatiales	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
CH2_k127_141891_1	1163617.SCD_n02958	5.152e-162	525.0	COG1269@1|root,COG1269@2|Bacteria,1MXZG@1224|Proteobacteria,2VMAH@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Protein of unknown function (DUF3485)	epsH	-	-	-	-	-	-	-	-	-	-	-	DUF3485,Exosortase_EpsH
CH2_k127_141891_2	1163617.SCD_n02957	3.772e-153	493.0	COG0438@1|root,COG0438@2|Bacteria,1MVIM@1224|Proteobacteria,2VJT7@28216|Betaproteobacteria	28216|Betaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
CH2_k127_141891_0	1163617.SCD_n02956	1.781e-174	559.0	COG2348@1|root,COG2348@2|Bacteria,1MXFY@1224|Proteobacteria,2VNEW@28216|Betaproteobacteria	28216|Betaproteobacteria	V	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
CH2_k127_141891_3	1163617.SCD_n02955	5.582e-138	443.0	COG0726@1|root,COG0726@2|Bacteria,1MWMZ@1224|Proteobacteria,2VIB9@28216|Betaproteobacteria	28216|Betaproteobacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3473,Polysacc_deac_1
CH2_k127_141891_5	323261.Noc_1976	1.507e-37	142.0	COG0381@1|root,COG0381@2|Bacteria,1QUYI@1224|Proteobacteria,1SZZW@1236|Gammaproteobacteria,1WXD4@135613|Chromatiales	135613|Chromatiales	M	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	-	-	5.1.3.14,5.1.3.23	ko:K01791,ko:K13019	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420,R09600	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
CH2_k127_1618808_3	1163617.SCD_n00223	2.267e-40	152.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,2VHYQ@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Vitamin B12 dependent methionine synthase activation	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
CH2_k127_1618808_2	1163617.SCD_n00224	4.454e-62	215.0	COG0607@1|root,COG0607@2|Bacteria,1REHH@1224|Proteobacteria,2VTFS@28216|Betaproteobacteria	28216|Betaproteobacteria	P	rhodanese-related sulfurtransferase	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CH2_k127_1618808_4	1123368.AUIS01000023_gene901	6.929e-28	116.0	2E8UR@1|root,33355@2|Bacteria,1MYPY@1224|Proteobacteria,1S6SI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_1618808_0	1123393.KB891330_gene898	4.309e-121	399.0	COG1814@1|root,COG1814@2|Bacteria,1MUZE@1224|Proteobacteria,2VJ27@28216|Betaproteobacteria,1KSVB@119069|Hydrogenophilales	119069|Hydrogenophilales	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
CH2_k127_1618808_1	580332.Slit_0062	3.812e-64	222.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,2VHRV@28216|Betaproteobacteria,44V3K@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Magnesium chelatase, subunit ChlI C-terminal	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
CH2_k127_177331_1	1173028.ANKO01000042_gene833	7.125e-09	58.0	2ETGP@1|root,33M0J@2|Bacteria,1GAIU@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_177331_0	640081.Dsui_2420	1.185e-232	725.0	COG1032@1|root,COG1032@2|Bacteria,1MUG3@1224|Proteobacteria,2VJ9A@28216|Betaproteobacteria,2KV3Z@206389|Rhodocyclales	206389|Rhodocyclales	C	UPF0313 protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
CH2_k127_1873637_1	1123392.AQWL01000003_gene402	1.622e-180	568.0	COG0226@1|root,COG0226@2|Bacteria,1MUAZ@1224|Proteobacteria,2VIJV@28216|Betaproteobacteria,1KSC1@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Part of the ABC transporter complex PstSACB involved in phosphate import	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
CH2_k127_1873637_0	1123393.KB891327_gene371	2.577e-188	590.0	COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,2VH4G@28216|Betaproteobacteria,1KS4M@119069|Hydrogenophilales	119069|Hydrogenophilales	P	probably responsible for the translocation of the substrate across the membrane	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
CH2_k127_1873637_2	1123393.KB891327_gene372	1.765e-161	510.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,2VH6Y@28216|Betaproteobacteria,1KRK6@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
CH2_k127_1873637_3	1123392.AQWL01000003_gene399	3.8e-143	456.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,2VI4J@28216|Betaproteobacteria,1KSBR@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
CH2_k127_1873637_4	543728.Vapar_1055	1.746e-10	64.0	2EC4W@1|root,3363P@2|Bacteria,1N7E3@1224|Proteobacteria,2VWC7@28216|Betaproteobacteria,4AFB8@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_1886000_3	4432.XP_010248290.1	1.738e-10	67.0	COG0740@1|root,KOG0840@2759|Eukaryota	2759|Eukaryota	OU	serine-type endopeptidase activity	-	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease,Trigger_C
CH2_k127_1886000_2	1123392.AQWL01000008_gene1182	3.542e-118	382.0	COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,2VHAZ@28216|Betaproteobacteria,1KRDV@119069|Hydrogenophilales	119069|Hydrogenophilales	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
CH2_k127_1886000_1	1123392.AQWL01000008_gene1181	7.803e-222	693.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,2VIEU@28216|Betaproteobacteria,1KRGT@119069|Hydrogenophilales	119069|Hydrogenophilales	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
CH2_k127_1886000_0	323848.Nmul_A2338	3.789e-315	973.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,2VIAU@28216|Betaproteobacteria,3727H@32003|Nitrosomonadales	28216|Betaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
CH2_k127_1917024_4	1163617.SCD_n01267	1.632e-13	70.0	COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,2VNCG@28216|Betaproteobacteria	28216|Betaproteobacteria	N	PFAM MotA TolQ ExbB proton channel	motC	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
CH2_k127_1917024_1	1163617.SCD_n01268	1.187e-81	279.0	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,2VKC4@28216|Betaproteobacteria	28216|Betaproteobacteria	N	PFAM OmpA MotB domain protein	motB1	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
CH2_k127_1917024_3	1163617.SCD_n01269	3.766e-36	142.0	COG3418@1|root,COG3418@2|Bacteria,1NGUP@1224|Proteobacteria,2VXS1@28216|Betaproteobacteria	28216|Betaproteobacteria	N	PFAM FlgN family protein	flgN	-	-	ko:K02399	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgN
CH2_k127_1917024_5	748247.AZKH_1304	6.2e-10	64.0	COG2747@1|root,COG2747@2|Bacteria,1NGJA@1224|Proteobacteria,2VWP5@28216|Betaproteobacteria,2KXGB@206389|Rhodocyclales	206389|Rhodocyclales	N	negative regulator of flagellin synthesis	-	-	-	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgM
CH2_k127_1917024_2	1163617.SCD_n01706	1.017e-52	194.0	COG1261@1|root,COG1261@2|Bacteria,1N1SA@1224|Proteobacteria,2VR6V@28216|Betaproteobacteria	28216|Betaproteobacteria	N	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly	flgA	-	-	ko:K02386	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	ChapFlgA
CH2_k127_1917024_0	1163617.SCD_n01598	3.459e-286	889.0	COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,2VH0V@28216|Betaproteobacteria	28216|Betaproteobacteria	KL	Helicase	dinG	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,ResIII
CH2_k127_1938945_9	1163617.SCD_n02652	4.26e-08	57.0	COG1959@1|root,COG1959@2|Bacteria,1RE3F@1224|Proteobacteria,2VRIR@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
CH2_k127_1938945_3	1163617.SCD_n02653	7.118e-121	397.0	COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,2VJ3C@28216|Betaproteobacteria	28216|Betaproteobacteria	O	cytochrome oxidase assembly	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
CH2_k127_1938945_5	1266925.JHVX01000013_gene1629	1.852e-70	244.0	COG0132@1|root,COG0132@2|Bacteria,1RDRK@1224|Proteobacteria,2VR4C@28216|Betaproteobacteria,371P7@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	-	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
CH2_k127_1938945_4	1288494.EBAPG3_1530	5.504e-91	309.0	COG1686@1|root,COG1686@2|Bacteria,1MWZA@1224|Proteobacteria,2VH1S@28216|Betaproteobacteria,371XF@32003|Nitrosomonadales	28216|Betaproteobacteria	M	Beta-lactamase enzyme family	pbpG	-	-	ko:K07262	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
CH2_k127_1938945_1	1163617.SCD_n00777	2.383e-177	580.0	COG1639@1|root,COG3852@1|root,COG1639@2|Bacteria,COG3852@2|Bacteria,1R444@1224|Proteobacteria,2VJPB@28216|Betaproteobacteria	28216|Betaproteobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_3,HATPase_c,HDOD
CH2_k127_1938945_0	292415.Tbd_0085	2.597e-262	826.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_4,PAS_9,Response_reg
CH2_k127_1938945_8	580332.Slit_2739	5.158e-36	137.0	COG0228@1|root,COG0228@2|Bacteria,1MZCT@1224|Proteobacteria,2VTYP@28216|Betaproteobacteria,44W0A@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
CH2_k127_1938945_7	243365.CV_3674	3.585e-58	206.0	COG0806@1|root,COG0806@2|Bacteria,1MWQR@1224|Proteobacteria,2VQ0H@28216|Betaproteobacteria,2KR7B@206351|Neisseriales	206351|Neisseriales	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
CH2_k127_1938945_2	1163617.SCD_n02459	6.875e-131	421.0	COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,2VHPY@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
CH2_k127_1938945_6	292415.Tbd_2376	1.076e-62	216.0	COG0335@1|root,COG0335@2|Bacteria,1RH3A@1224|Proteobacteria,2VR2S@28216|Betaproteobacteria,1KRQN@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Ribosomal protein L19	-	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
CH2_k127_1958433_4	1485544.JQKP01000009_gene850	1.421e-27	112.0	COG1718@1|root,COG1718@2|Bacteria,1MXY2@1224|Proteobacteria,2VJ0H@28216|Betaproteobacteria,44WBT@713636|Nitrosomonadales	28216|Betaproteobacteria	DT	RIO1 family	-	-	2.7.11.1	ko:K07178	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko01001,ko03009	-	-	-	RIO1
CH2_k127_1958433_2	1123392.AQWL01000006_gene594	2.567e-77	278.0	COG1073@1|root,COG1073@2|Bacteria,1N1WH@1224|Proteobacteria,2W50B@28216|Betaproteobacteria,1KS36@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Protein of unknown function (DUF3530)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3530
CH2_k127_1958433_0	1163617.SCD_n02855	1.507e-110	363.0	COG0730@1|root,COG0730@2|Bacteria,1R3V4@1224|Proteobacteria,2VKXN@28216|Betaproteobacteria	28216|Betaproteobacteria	S	membrane transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	TauE
CH2_k127_1958433_1	323848.Nmul_A0614	4.05e-83	277.0	COG2947@1|root,COG2947@2|Bacteria,1RHRU@1224|Proteobacteria,2VRIB@28216|Betaproteobacteria,3732K@32003|Nitrosomonadales	28216|Betaproteobacteria	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
CH2_k127_1958433_3	1163617.SCD_n02857	3.939e-76	259.0	COG0212@1|root,COG0212@2|Bacteria,1MZG0@1224|Proteobacteria,2VJZE@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	fthC	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
CH2_k127_1972518_10	1123368.AUIS01000006_gene598	1.752e-12	68.0	COG1340@1|root,COG1340@2|Bacteria	2|Bacteria	KT	protein secretion by the type IV secretion system	potC	-	2.1.1.172,2.1.1.80,3.1.1.61	ko:K00564,ko:K02026,ko:K10716,ko:K11070,ko:K13924,ko:K14393	ko02010,ko02020,ko02030,map02010,map02020,map02030	M00207,M00299,M00506	R07234	RC00003	ko00000,ko00001,ko00002,ko01000,ko02000,ko02022,ko02035,ko03009	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6,2.A.21.7,3.A.1.1,3.A.1.11.1	-	-	Abhydrolase_8,BPD_transp_1,CheB_methylest,CheR,CheR_N,HATPase_c,HisKA,Ion_trans_2,PAS_4,PhageMin_Tail
CH2_k127_1972518_7	640081.Dsui_1263	1.188e-65	229.0	COG4665@1|root,COG4665@2|Bacteria,1RHBW@1224|Proteobacteria,2VRCB@28216|Betaproteobacteria,2KWFP@206389|Rhodocyclales	206389|Rhodocyclales	Q	TRAP-type mannitol chloroaromatic compound transport system, small permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
CH2_k127_1972518_4	1279038.KB907337_gene483	9.834e-220	692.0	COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,2TQNR@28211|Alphaproteobacteria,2JQE2@204441|Rhodospirillales	204441|Rhodospirillales	Q	COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
CH2_k127_1972518_0	1163617.SCD_n01412	0.0	1099.0	COG2199@1|root,COG2200@1|root,COG2203@1|root,COG3290@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,COG2203@2|Bacteria,COG3290@2|Bacteria,1RGKE@1224|Proteobacteria	1224|Proteobacteria	T	GAF domain	-	-	3.1.4.52	ko:K20962	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000	-	-	-	EAL,GAF,GAF_2,GGDEF,HWE_HK,PAS,PAS_3,PAS_4,PAS_8
CH2_k127_1972518_6	279714.FuraDRAFT_0886	4.377e-164	523.0	COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,2VH1J@28216|Betaproteobacteria,2KQJ4@206351|Neisseriales	206351|Neisseriales	C	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	-	-	-	-	-	-	-	-	-	-	-	DctP
CH2_k127_1972518_5	1288494.EBAPG3_16330	4.934e-186	590.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,371SP@32003|Nitrosomonadales	28216|Betaproteobacteria	JKL	Belongs to the DEAD box helicase family	rhlE1	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
CH2_k127_1972518_3	1163617.SCD_n01403	3.305e-227	708.0	COG2070@1|root,COG2070@2|Bacteria,1N52W@1224|Proteobacteria,2VJ45@28216|Betaproteobacteria	28216|Betaproteobacteria	S	2-Nitropropane dioxygenase	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
CH2_k127_1972518_9	1123393.KB891327_gene390	1.181e-33	134.0	2BW9S@1|root,32Z6F@2|Bacteria,1N7ID@1224|Proteobacteria,2VVR9@28216|Betaproteobacteria,1KTCI@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Protein of unknown function (DUF2818)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2818
CH2_k127_1972518_2	1163617.SCD_n00952	4.642e-234	731.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,2VHWX@28216|Betaproteobacteria	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
CH2_k127_1972518_1	1485544.JQKP01000010_gene814	3.994e-251	781.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,2VIAX@28216|Betaproteobacteria,44VBV@713636|Nitrosomonadales	28216|Betaproteobacteria	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
CH2_k127_1972518_8	1163617.SCD_n00950	6.852e-49	176.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,2VJ2J@28216|Betaproteobacteria	28216|Betaproteobacteria	CP	NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
CH2_k127_1993413_0	265072.Mfla_2272	8.517e-151	481.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,2VHAP@28216|Betaproteobacteria,2KME5@206350|Nitrosomonadales	206350|Nitrosomonadales	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
CH2_k127_1993413_1	1163617.SCD_n02489	1.003e-106	353.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,2VH2H@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10,6.3.2.13	ko:K01929,ko:K15792	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R02788,R04573,R04617	RC00064,RC00090,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CH2_k127_2104617_9	870187.Thini_0397	3.225e-24	102.0	COG0440@1|root,COG0440@2|Bacteria,1RAGN@1224|Proteobacteria,1S20I@1236|Gammaproteobacteria,460NY@72273|Thiotrichales	72273|Thiotrichales	E	TIGRFAM Acetolactate synthase, small subunit	-	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_5,ALS_ss_C
CH2_k127_2104617_0	1163617.SCD_n00818	4.4e-323	994.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2VJ55@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Acetolactate synthase	ilvI	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CH2_k127_2104617_5	1163617.SCD_n00817	5.322e-82	276.0	COG1595@1|root,COG1595@2|Bacteria,1R9WC@1224|Proteobacteria,2VQ28@28216|Betaproteobacteria	28216|Betaproteobacteria	K	RNA polymerase	sigE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CH2_k127_2104617_10	640081.Dsui_3531	6.163e-12	71.0	2E95F@1|root,333E6@2|Bacteria,1N8N7@1224|Proteobacteria,2VWBC@28216|Betaproteobacteria,2KXMZ@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function (DUF3619)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3619
CH2_k127_2104617_8	1163617.SCD_n00815	1.779e-27	117.0	2E3UK@1|root,32YRY@2|Bacteria,1N74J@1224|Proteobacteria,2VVQ2@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF3106)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3106
CH2_k127_2104617_7	1163617.SCD_n00814	5.777e-44	166.0	COG1714@1|root,COG1714@2|Bacteria,1REEC@1224|Proteobacteria,2VRE0@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM RDD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	RDD
CH2_k127_2104617_3	1163617.SCD_n00813	3.573e-153	492.0	COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,2VHA1@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Permease, YjgP YjgQ family	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
CH2_k127_2104617_4	1163617.SCD_n00812	7.151e-140	452.0	COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,2VH9C@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Permease, YjgP YjgQ family	lptF	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
CH2_k127_2104617_1	1163617.SCD_n00811	3.332e-256	797.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,2VH79@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
CH2_k127_2104617_6	1163617.SCD_n00810	4.32e-59	208.0	COG2927@1|root,COG2927@2|Bacteria,1MZ3V@1224|Proteobacteria,2VTYC@28216|Betaproteobacteria	28216|Betaproteobacteria	L	dna polymerase III (Chi subunit)	holC	-	2.7.7.7	ko:K02339	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_chi
CH2_k127_2104617_2	1163617.SCD_n00808	1.84e-179	565.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,2VH5Z@28216|Betaproteobacteria	28216|Betaproteobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
CH2_k127_2118777_1	580332.Slit_1181	9.043e-88	293.0	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,44WC2@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S)	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_9,dCache_2
CH2_k127_2118777_2	1288494.EBAPG3_20620	1.843e-74	256.0	COG1544@1|root,COG1544@2|Bacteria,1RJ55@1224|Proteobacteria,2VR5Q@28216|Betaproteobacteria,372T2@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Sigma 54 modulation protein / S30EA ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	CSD,Ribosomal_S30AE
CH2_k127_2118777_0	1163617.SCD_n02336	2.944e-111	370.0	COG4783@1|root,COG4783@2|Bacteria,1R84W@1224|Proteobacteria,2VIBK@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM peptidase M48 Ste24p	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
CH2_k127_2118777_3	1163617.SCD_n02335	1.008e-57	205.0	COG3103@1|root,COG3103@2|Bacteria,1N6AX@1224|Proteobacteria,2VVME@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Bacterial SH3 domain	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3,SH3_4
CH2_k127_2118777_4	1163617.SCD_n02334	1.777e-33	134.0	COG4252@1|root,COG4252@2|Bacteria,1R9GK@1224|Proteobacteria,2VKE8@28216|Betaproteobacteria	28216|Betaproteobacteria	T	PFAM CHASE2 domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE2
CH2_k127_2257595_9	1485544.JQKP01000005_gene362	1.334e-14	76.0	COG3147@1|root,COG3147@2|Bacteria,1R7IV@1224|Proteobacteria,2VPE1@28216|Betaproteobacteria,44VYQ@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Sporulation related domain	dedD	-	-	ko:K03749	-	-	-	-	ko00000	-	-	-	SPOR
CH2_k127_2257595_3	1163617.SCD_n00886	2.958e-165	530.0	COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,2VI0H@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
CH2_k127_2257595_4	1163617.SCD_n00885	2.174e-156	496.0	COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,2VHEQ@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
CH2_k127_2257595_5	1163617.SCD_n00884	5.169e-117	382.0	COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,2VI78@28216|Betaproteobacteria	28216|Betaproteobacteria	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
CH2_k127_2257595_0	1163617.SCD_n00881	8.985e-229	712.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,2VHV3@28216|Betaproteobacteria	28216|Betaproteobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	GO:0000162,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0042802,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CH2_k127_2257595_7	580332.Slit_2116	9.11e-81	273.0	COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,2VPZV@28216|Betaproteobacteria,44VEB@713636|Nitrosomonadales	28216|Betaproteobacteria	E	N-(5'phosphoribosyl)anthranilate (PRA) isomerase	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
CH2_k127_2257595_6	1163617.SCD_n00879	1.144e-116	382.0	COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,2VI0R@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
CH2_k127_2257595_8	1163617.SCD_n00878	3.639e-33	136.0	COG0619@1|root,COG0619@2|Bacteria,1N7EI@1224|Proteobacteria,2VWJT@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	-	-	-	-	-	-	-	-	-	-	-	-	CbiQ
CH2_k127_2257595_2	1163617.SCD_n00877	5.388e-214	698.0	COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,2VHX1@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	pilus assembly protein FimV	fimV	-	-	ko:K08086	-	-	-	-	ko00000	-	-	-	LysM
CH2_k127_2257595_1	1163617.SCD_n00876	4.467e-226	702.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,2VH2N@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
CH2_k127_2268869_1	1163617.SCD_n02809	4.662e-34	131.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	type II secretion system protein E	-	-	-	ko:K02454,ko:K02652,ko:K12276	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
CH2_k127_2268869_0	1123368.AUIS01000016_gene2550	1.14e-47	183.0	2DM2X@1|root,31HF3@2|Bacteria,1RIYM@1224|Proteobacteria,1SFV4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_2268869_3	1095769.CAHF01000022_gene425	2.417e-33	135.0	2E3Q5@1|root,32YN4@2|Bacteria,1NA23@1224|Proteobacteria,2VVXW@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PilN
CH2_k127_2268869_2	1123368.AUIS01000016_gene2548	1.65e-33	137.0	COG3167@1|root,COG3167@2|Bacteria,1NCJI@1224|Proteobacteria,1SIA2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	Pilus assembly protein, PilO	-	-	-	-	-	-	-	-	-	-	-	-	PilO,T2SSM_b
CH2_k127_2343741_10	1163617.SCD_n00650	2.829e-79	266.0	COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,2VHG6@28216|Betaproteobacteria	28216|Betaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
CH2_k127_2343741_4	1288494.EBAPG3_30050	6.089e-110	358.0	COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,2VGZH@28216|Betaproteobacteria,371ZR@32003|Nitrosomonadales	28216|Betaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
CH2_k127_2343741_11	265072.Mfla_0303	9.165e-74	248.0	COG0100@1|root,COG0100@2|Bacteria,1RD0A@1224|Proteobacteria,2VR8I@28216|Betaproteobacteria,2KMK2@206350|Nitrosomonadales	206350|Nitrosomonadales	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
CH2_k127_2343741_16	1163617.SCD_n00647	1.696e-58	205.0	COG0099@1|root,COG0099@2|Bacteria,1RD1G@1224|Proteobacteria,2VR2K@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
CH2_k127_2343741_28	62928.azo3395	1.45e-12	69.0	COG0257@1|root,COG0257@2|Bacteria,1NGEI@1224|Proteobacteria,2VXPQ@28216|Betaproteobacteria,2KXKB@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
CH2_k127_2343741_23	626418.bglu_1g02790	3.378e-38	143.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,2VU9X@28216|Betaproteobacteria,1K9AT@119060|Burkholderiaceae	28216|Betaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
CH2_k127_2343741_0	1163617.SCD_n00645	1.642e-238	743.0	COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,2VHQH@28216|Betaproteobacteria	28216|Betaproteobacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
CH2_k127_2343741_14	580332.Slit_0786	1.171e-65	226.0	COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,2VRAK@28216|Betaproteobacteria,44VVB@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
CH2_k127_2343741_26	1485544.JQKP01000001_gene1128	2.551e-24	103.0	COG1841@1|root,COG1841@2|Bacteria,1N6ZE@1224|Proteobacteria,2VVPT@28216|Betaproteobacteria,44W34@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Ribosomal protein L30p/L7e	rpmD	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
CH2_k127_2343741_8	1266925.JHVX01000018_gene1806	7.307e-89	294.0	COG0098@1|root,COG0098@2|Bacteria,1MUS4@1224|Proteobacteria,2VQ80@28216|Betaproteobacteria,3723A@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
CH2_k127_2343741_19	557598.LHK_00269	3.374e-52	186.0	COG0256@1|root,COG0256@2|Bacteria,1RGY7@1224|Proteobacteria,2VSH0@28216|Betaproteobacteria,2KR4N@206351|Neisseriales	206351|Neisseriales	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
CH2_k127_2343741_9	1266925.JHVX01000018_gene1808	2.699e-84	282.0	COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,2VQ4W@28216|Betaproteobacteria,372YI@32003|Nitrosomonadales	28216|Betaproteobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
CH2_k127_2343741_15	323848.Nmul_A0781	4.444e-63	218.0	COG0096@1|root,COG0096@2|Bacteria,1RDG3@1224|Proteobacteria,2VRBD@28216|Betaproteobacteria,373A5@32003|Nitrosomonadales	28216|Betaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
CH2_k127_2343741_24	580332.Slit_0780	1.099e-37	145.0	COG0199@1|root,COG0199@2|Bacteria,1MZDT@1224|Proteobacteria,2VSVX@28216|Betaproteobacteria,44VZE@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
CH2_k127_2343741_6	1163617.SCD_n00637	5.44e-100	327.0	COG0094@1|root,COG0094@2|Bacteria,1MUU9@1224|Proteobacteria,2VHCP@28216|Betaproteobacteria	28216|Betaproteobacteria	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
CH2_k127_2343741_20	1163617.SCD_n00636	1.016e-51	184.0	COG0198@1|root,COG0198@2|Bacteria,1MZQD@1224|Proteobacteria,2VUC6@28216|Betaproteobacteria	28216|Betaproteobacteria	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
CH2_k127_2343741_13	76114.ebB127	1.396e-68	233.0	COG0093@1|root,COG0093@2|Bacteria,1RCWZ@1224|Proteobacteria,2VR2N@28216|Betaproteobacteria,2KWBZ@206389|Rhodocyclales	206389|Rhodocyclales	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
CH2_k127_2343741_25	1123393.KB891318_gene2143	1.086e-36	139.0	COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,2VU2G@28216|Betaproteobacteria,1KRUG@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Ribosomal protein S17	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_S17
CH2_k127_2343741_27	1163617.SCD_n00633	3.651e-21	93.0	COG0255@1|root,COG0255@2|Bacteria	2|Bacteria	J	Belongs to the universal ribosomal protein uL29 family	rpmC	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
CH2_k127_2343741_12	1196083.SALWKB12_1431	5.09e-69	236.0	COG0197@1|root,COG0197@2|Bacteria,1RA0Z@1224|Proteobacteria,2VQ0A@28216|Betaproteobacteria,2KQUU@206351|Neisseriales	206351|Neisseriales	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
CH2_k127_2343741_3	1163617.SCD_n00631	4.71e-124	400.0	COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,2VHQN@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
CH2_k127_2343741_18	1163617.SCD_n00630	2.42e-55	194.0	COG0091@1|root,COG0091@2|Bacteria,1RH0W@1224|Proteobacteria,2VSE6@28216|Betaproteobacteria	28216|Betaproteobacteria	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
CH2_k127_2343741_21	292415.Tbd_0409	1.586e-50	179.0	COG0185@1|root,COG0185@2|Bacteria,1RGYX@1224|Proteobacteria,2VSGE@28216|Betaproteobacteria,1KRQC@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
CH2_k127_2343741_2	1163617.SCD_n00628	1.278e-154	490.0	COG0090@1|root,COG0090@2|Bacteria,1MVTD@1224|Proteobacteria,2VHSD@28216|Betaproteobacteria	28216|Betaproteobacteria	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
CH2_k127_2343741_22	640081.Dsui_0357	3.773e-45	165.0	COG0089@1|root,COG0089@2|Bacteria,1MZXX@1224|Proteobacteria,2VU1C@28216|Betaproteobacteria,2KWRX@206389|Rhodocyclales	206389|Rhodocyclales	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
CH2_k127_2343741_7	1163617.SCD_n00626	4.319e-99	326.0	COG0088@1|root,COG0088@2|Bacteria,1MXPF@1224|Proteobacteria,2VHS6@28216|Betaproteobacteria	28216|Betaproteobacteria	J	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
CH2_k127_2343741_5	1163617.SCD_n00625	1.794e-101	334.0	COG0087@1|root,COG0087@2|Bacteria,1MUST@1224|Proteobacteria,2VJ3V@28216|Betaproteobacteria	28216|Betaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
CH2_k127_2343741_17	1163617.SCD_n00624	1.96e-57	201.0	COG0051@1|root,COG0051@2|Bacteria,1RGWF@1224|Proteobacteria,2VSDQ@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
CH2_k127_2343741_1	1163617.SCD_n00623	5.929e-164	516.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,2VH5D@28216|Betaproteobacteria	28216|Betaproteobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
CH2_k127_2354461_0	1163617.SCD_n01990	1.992e-144	459.0	COG1944@1|root,COG1944@2|Bacteria,1MV7K@1224|Proteobacteria,2VHZY@28216|Betaproteobacteria	28216|Betaproteobacteria	O	YcaO cyclodehydratase, ATP-ad Mg2+-binding	-	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	YcaO
CH2_k127_2354461_2	1163617.SCD_n01402	2.244e-30	122.0	2E9RY@1|root,333Y3@2|Bacteria,1NB96@1224|Proteobacteria,2VX0F@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_2354461_1	517418.Ctha_0772	1.067e-48	178.0	COG2839@1|root,COG2839@2|Bacteria,1FE53@1090|Chlorobi	1090|Chlorobi	S	Protein of unknown function (DUF456)	-	-	-	ko:K09793	-	-	-	-	ko00000	-	-	-	DUF456
CH2_k127_2354461_3	1123368.AUIS01000003_gene1753	5.309e-24	102.0	COG0346@1|root,COG0346@2|Bacteria,1RH3J@1224|Proteobacteria,1S60C@1236|Gammaproteobacteria,2NCXN@225057|Acidithiobacillales	225057|Acidithiobacillales	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CH2_k127_2365596_1	1288494.EBAPG3_9560	5.858e-18	83.0	COG2270@1|root,COG2270@2|Bacteria,1MWXB@1224|Proteobacteria,2VKNE@28216|Betaproteobacteria,372VG@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Vacuole effluxer Atg22 like	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
CH2_k127_2365596_0	1120999.JONM01000009_gene369	1.188e-270	840.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2VHGH@28216|Betaproteobacteria,2KQ8F@206351|Neisseriales	206351|Neisseriales	S	ATP synthase F1, epsilon subunit	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
CH2_k127_2365596_2	265072.Mfla_2516	5.939e-11	74.0	COG0342@1|root,COG0342@2|Bacteria,1MVFS@1224|Proteobacteria,2VHD9@28216|Betaproteobacteria,2KKJP@206350|Nitrosomonadales	206350|Nitrosomonadales	U	PFAM Glutamate-cysteine ligase	-	-	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	GshA
CH2_k127_2386564_5	1163617.SCD_n00514	3.066e-24	102.0	COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,2VIFC@28216|Betaproteobacteria	28216|Betaproteobacteria	S	domain protein	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
CH2_k127_2386564_1	1163617.SCD_n00513	7.3e-82	277.0	COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,2VPCK@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
CH2_k127_2386564_4	1000565.METUNv1_01926	2.381e-29	117.0	COG1758@1|root,COG1758@2|Bacteria,1N6TX@1224|Proteobacteria,2VVUH@28216|Betaproteobacteria,2KX71@206389|Rhodocyclales	206389|Rhodocyclales	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
CH2_k127_2386564_0	1163617.SCD_n00511	0.0	1097.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,2VIA1@28216|Betaproteobacteria	28216|Betaproteobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	spoT	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
CH2_k127_2386564_2	582744.Msip34_0054	3.809e-57	201.0	COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,2VRQ3@28216|Betaproteobacteria,2KMVS@206350|Nitrosomonadales	206350|Nitrosomonadales	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
CH2_k127_2386564_3	555778.Hneap_1065	7.694e-35	147.0	2E1KF@1|root,32WXX@2|Bacteria,1N6CC@1224|Proteobacteria,1SB3I@1236|Gammaproteobacteria,1X11J@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_2386564_6	228410.NE1850	5.787e-13	73.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,2VHE8@28216|Betaproteobacteria,372I7@32003|Nitrosomonadales	28216|Betaproteobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
CH2_k127_2428050_4	1163617.SCD_n01561	6.929e-149	474.0	28HY3@1|root,2Z83I@2|Bacteria,1R5P3@1224|Proteobacteria,2VZ4M@28216|Betaproteobacteria	28216|Betaproteobacteria	S	phosphoenolpyruvate carboxykinase (diphosphate) activity	-	-	4.1.1.38	ko:K20370	ko00620,ko01100,map00620,map01100	-	R00346	RC02741	ko00000,ko00001,ko01000	-	-	-	-
CH2_k127_2428050_14	1121937.AUHJ01000026_gene17	0.0001668	44.0	COG2826@1|root,COG2826@2|Bacteria,1PP49@1224|Proteobacteria,1RN7B@1236|Gammaproteobacteria,46DI7@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Integrase core domain	insI	GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004803,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006310,GO:0006313,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0030983,GO:0032135,GO:0032196,GO:0032991,GO:0032993,GO:0034641,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	-	ko:K07482	-	-	-	-	ko00000	-	-	-	HTH_38,rve
CH2_k127_2428050_0	1163617.SCD_n01569	0.0	1096.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,2VH2W@28216|Betaproteobacteria	28216|Betaproteobacteria	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
CH2_k127_2428050_1	1163617.SCD_n01568	4.231e-177	566.0	COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,2VJVZ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	protein conserved in bacteria	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
CH2_k127_2428050_9	1123392.AQWL01000006_gene651	2.251e-47	172.0	COG3118@1|root,COG3118@2|Bacteria,1MV0R@1224|Proteobacteria,2VI6Z@28216|Betaproteobacteria,1KT6E@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin
CH2_k127_2428050_3	1163617.SCD_n01507	4.755e-151	482.0	COG1092@1|root,COG1092@2|Bacteria,1QW1V@1224|Proteobacteria,2WH6G@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Belongs to the methyltransferase superfamily	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
CH2_k127_2428050_2	1163617.SCD_n01508	8.388e-164	527.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria	1224|Proteobacteria	L	Belongs to the DEAD box helicase family	rhlE2	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
CH2_k127_2428050_13	1123392.AQWL01000003_gene321	3.539e-27	113.0	COG1923@1|root,COG1923@2|Bacteria,1MZM1@1224|Proteobacteria,2VTXK@28216|Betaproteobacteria,1KTA7@119069|Hydrogenophilales	119069|Hydrogenophilales	J	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs	hfq	-	-	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	-	-	-	ko00000,ko00001,ko03019,ko03036	-	-	-	Hfq
CH2_k127_2428050_8	1163617.SCD_n01471	4.272e-83	287.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,2VJZP@28216|Betaproteobacteria	28216|Betaproteobacteria	M	peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
CH2_k127_2428050_12	1266925.JHVX01000006_gene2137	2.202e-31	124.0	COG0271@1|root,COG0271@2|Bacteria,1MZG5@1224|Proteobacteria,2VVNP@28216|Betaproteobacteria,373JI@32003|Nitrosomonadales	28216|Betaproteobacteria	T	BolA-like protein	bolA	-	-	ko:K05527	-	-	-	-	ko00000,ko03000	-	-	-	BolA
CH2_k127_2428050_10	1454004.AW11_00311	7.373e-44	162.0	COG2350@1|root,COG2350@2|Bacteria,1MZ9Z@1224|Proteobacteria,2VUM7@28216|Betaproteobacteria,1KQX3@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	YCII-related domain	yciI	-	-	ko:K09780	-	-	-	-	ko00000	-	-	-	YCII
CH2_k127_2428050_7	1163617.SCD_n01474	1.943e-94	312.0	COG2917@1|root,COG2917@2|Bacteria,1NWIZ@1224|Proteobacteria,2VRHB@28216|Betaproteobacteria	28216|Betaproteobacteria	D	probably involved in intracellular septation	ispZ	-	-	ko:K06190	-	-	-	-	ko00000	-	-	-	IspA
CH2_k127_2428050_5	1266925.JHVX01000020_gene1776	1.824e-112	369.0	COG0613@1|root,COG0613@2|Bacteria,1MWIH@1224|Proteobacteria,2VHB2@28216|Betaproteobacteria,372I4@32003|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM PHP C-terminal	-	GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0097657	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
CH2_k127_2428050_6	261292.Nit79A3_3414	7.293e-104	340.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,2VH4T@28216|Betaproteobacteria,3729G@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the SUA5 family	yciO	-	-	-	-	-	-	-	-	-	-	-	Sua5_yciO_yrdC
CH2_k127_2428050_11	1163617.SCD_n01477	3.435e-42	156.0	COG1994@1|root,COG1994@2|Bacteria,1NSFF@1224|Proteobacteria,2VHAM@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
CH2_k127_2506300_6	1163617.SCD_n02061	9.63e-25	106.0	2E2DR@1|root,32XIE@2|Bacteria,1N271@1224|Proteobacteria,2W4PR@28216|Betaproteobacteria	28216|Betaproteobacteria	S	SseB protein N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	SseB
CH2_k127_2506300_2	243233.MCA2268	3.437e-110	360.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,1RNVM@1236|Gammaproteobacteria,1XE0Y@135618|Methylococcales	135618|Methylococcales	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
CH2_k127_2506300_3	243233.MCA2267	5.338e-109	356.0	COG0778@1|root,COG0778@2|Bacteria,1RA6E@1224|Proteobacteria,1S460@1236|Gammaproteobacteria,1XF58@135618|Methylococcales	135618|Methylococcales	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CH2_k127_2506300_1	671143.DAMO_0362	1.912e-118	387.0	COG2837@1|root,COG2837@2|Bacteria	2|Bacteria	P	iron assimilation	dyp	-	-	ko:K07223	-	-	-	-	ko00000	-	-	-	Dyp_perox
CH2_k127_2506300_7	426114.THI_3693	1.702e-19	98.0	294MD@1|root,2ZS0U@2|Bacteria,1NEY7@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_2506300_5	1480694.DC28_05645	2.271e-46	171.0	COG3012@1|root,COG3012@2|Bacteria,2J7G8@203691|Spirochaetes	203691|Spirochaetes	U	SEC-C domain protein	-	-	-	ko:K09858	-	-	-	-	ko00000	-	-	-	SEC-C
CH2_k127_2506300_0	1163617.SCD_n02065	9.625e-152	487.0	COG4360@1|root,COG4360@2|Bacteria,1RB5I@1224|Proteobacteria,2W0KI@28216|Betaproteobacteria	28216|Betaproteobacteria	F	ATP adenylyltransferase (5',5''-P-1,P-4-tetraphosphate phosphorylase II)	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_2506300_4	1163617.SCD_n02071	3.84e-108	353.0	COG0491@1|root,COG0491@2|Bacteria,1MUDN@1224|Proteobacteria,2VHMC@28216|Betaproteobacteria	28216|Betaproteobacteria	P	domain, Protein	ycbL	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CH2_k127_2506300_8	330214.NIDE1440	1.078e-09	61.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	-	-	5.1.1.20,5.5.1.1	ko:K01856,ko:K19802	ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220	M00568	R05300,R05390,R06989,R08116,R09229,R10938	RC00903,RC01038,RC01108,RC01321,RC01356,RC03309	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
CH2_k127_2509730_0	292415.Tbd_0010	1.637e-280	873.0	COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,1MUFZ@1224|Proteobacteria,2VHUF@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
CH2_k127_2509730_1	292415.Tbd_2415	4.768e-195	627.0	COG0699@1|root,COG0699@2|Bacteria,1MXBK@1224|Proteobacteria,2W1AV@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
CH2_k127_2509730_6	1131553.JIBI01000006_gene1111	3.285e-26	112.0	COG1872@1|root,COG1872@2|Bacteria,1MZ4E@1224|Proteobacteria,2VWDY@28216|Betaproteobacteria,373IG@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
CH2_k127_2509730_5	1163617.SCD_n00069	2.652e-63	222.0	COG0762@1|root,COG0762@2|Bacteria,1RCZV@1224|Proteobacteria,2VRHV@28216|Betaproteobacteria	28216|Betaproteobacteria	S	integral membrane protein	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
CH2_k127_2509730_4	1288494.EBAPG3_2590	1.897e-92	311.0	COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,2VJD1@28216|Betaproteobacteria,3728X@32003|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
CH2_k127_2509730_3	580332.Slit_2758	1.304e-94	315.0	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,2VHNY@28216|Betaproteobacteria,44V25@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
CH2_k127_2509730_2	1163617.SCD_n00073	7.827e-192	601.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,2VHHW@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	twitching motility protein	pilT	-	-	ko:K02669,ko:K12203	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2,3.A.7.10.1,3.A.7.9.1	-	-	T2SSE
CH2_k127_2546734_6	323261.Noc_0167	6.648e-35	134.0	COG1476@1|root,COG1476@2|Bacteria,1QWRE@1224|Proteobacteria,1T2XD@1236|Gammaproteobacteria,1X0ZS@135613|Chromatiales	135613|Chromatiales	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
CH2_k127_2546734_0	323848.Nmul_A2456	2.707e-258	807.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,2VHT1@28216|Betaproteobacteria,371R0@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
CH2_k127_2546734_5	1163617.SCD_n03012	1.577e-54	201.0	COG3087@1|root,COG3087@2|Bacteria,1RIU5@1224|Proteobacteria,2VTKT@28216|Betaproteobacteria	28216|Betaproteobacteria	D	PFAM Sporulation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
CH2_k127_2546734_4	1163617.SCD_n03013	2.948e-64	226.0	COG1651@1|root,COG1651@2|Bacteria,1RGWH@1224|Proteobacteria,2VSFV@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Thiol disulfide interchange protein	dsbA	-	-	ko:K03673	ko01503,map01503	M00728	-	-	ko00000,ko00001,ko00002,ko03110	-	-	-	DSBA,Thioredoxin_4
CH2_k127_2546734_2	1288494.EBAPG3_27740	3.978e-100	332.0	COG0300@1|root,COG0300@2|Bacteria,1PNDU@1224|Proteobacteria,2VIWD@28216|Betaproteobacteria,372WG@32003|Nitrosomonadales	28216|Betaproteobacteria	S	KR domain	wcbP	-	-	-	-	-	-	-	-	-	-	-	adh_short
CH2_k127_2546734_3	1163617.SCD_n03014	8.961e-67	233.0	COG2197@1|root,COG2197@2|Bacteria,1R434@1224|Proteobacteria,2WEVM@28216|Betaproteobacteria	28216|Betaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CH2_k127_2546734_1	717772.THIAE_02980	1.248e-103	343.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RR00@1236|Gammaproteobacteria,4601B@72273|Thiotrichales	72273|Thiotrichales	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CH2_k127_2571564_1	1163617.SCD_n00081	2.161e-132	428.0	COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,2VIZ3@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Belongs to the prokaryotic GSH synthase family	gshB	-	6.3.2.3	ko:K01920	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00497,R10994	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	GSH-S_ATP,GSH-S_N
CH2_k127_2571564_0	1163617.SCD_n00080	3.911e-171	541.0	COG0342@1|root,COG0342@2|Bacteria,1MVFS@1224|Proteobacteria,2VHD9@28216|Betaproteobacteria	28216|Betaproteobacteria	U	glutamate--cysteine ligase	gshA	-	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	GshA
CH2_k127_2698712_1	1163617.SCD_n01243	2.537e-152	485.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,2VIQ4@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
CH2_k127_2698712_0	1163617.SCD_n01244	6.895e-169	537.0	COG3317@1|root,COG3317@2|Bacteria,1N670@1224|Proteobacteria,2VHS5@28216|Betaproteobacteria	28216|Betaproteobacteria	M	(Lipo)protein	nlpB	-	-	ko:K07287	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	Lipoprotein_18
CH2_k127_2698712_3	1266925.JHVX01000013_gene1626	1.051e-108	357.0	COG1235@1|root,COG1235@2|Bacteria,1R5N4@1224|Proteobacteria,2VKSE@28216|Betaproteobacteria,372ZG@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
CH2_k127_2698712_6	1163617.SCD_n01246	2.372e-49	182.0	2E3EJ@1|root,32YDJ@2|Bacteria,1N8MS@1224|Proteobacteria,2VW4J@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_2698712_4	1163617.SCD_n01247	7.741e-72	244.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,2VRCR@28216|Betaproteobacteria	28216|Betaproteobacteria	O	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
CH2_k127_2698712_5	1236959.BAMT01000001_gene1109	5.469e-61	214.0	COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,2VQA2@28216|Betaproteobacteria,2KMMG@206350|Nitrosomonadales	206350|Nitrosomonadales	O	Peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
CH2_k127_2698712_2	582744.Msip34_1817	6.911e-125	405.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,2VI3Z@28216|Betaproteobacteria,2KKXU@206350|Nitrosomonadales	206350|Nitrosomonadales	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
CH2_k127_2701426_1	1095769.CAHF01000011_gene2539	7.572e-81	272.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria,47316@75682|Oxalobacteraceae	28216|Betaproteobacteria	NU	Type II secretion system (T2SS), protein E, N-terminal domain	-	-	-	ko:K02454,ko:K12276	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
CH2_k127_2701426_3	243365.CV_4383	4.669e-67	231.0	COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,2VR5W@28216|Betaproteobacteria,2KQZV@206351|Neisseriales	206351|Neisseriales	J	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
CH2_k127_2701426_2	748280.NH8B_3720	2.338e-74	255.0	COG2717@1|root,COG2717@2|Bacteria,1RDUP@1224|Proteobacteria,2VRBQ@28216|Betaproteobacteria,2KRFH@206351|Neisseriales	206351|Neisseriales	C	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain	msrQ	-	-	ko:K17247	-	-	-	-	ko00000	-	-	-	Ferric_reduct
CH2_k127_2701426_0	1123393.KB891331_gene2840	2.169e-134	431.0	COG2041@1|root,COG2041@2|Bacteria,1MUW0@1224|Proteobacteria,2VH08@28216|Betaproteobacteria,1KSIB@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Oxidoreductase molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
CH2_k127_2732872_0	1163617.SCD_n01923	5.443e-296	921.0	COG1449@1|root,COG1449@2|Bacteria,1Q9WP@1224|Proteobacteria,2VN9S@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Belongs to the glycosyl hydrolase 57 family	amyA	-	2.4.1.25	ko:K22451	ko00500,map00500	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH57	-	DUF1925,DUF1926,Glyco_hydro_57
CH2_k127_2732872_1	1163617.SCD_n01924	9.487e-116	379.0	COG1449@1|root,COG1449@2|Bacteria,1P2YJ@1224|Proteobacteria,2VHA4@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_57
CH2_k127_2853074_1	1304883.KI912532_gene1738	1.111e-104	347.0	COG3850@1|root,COG3850@2|Bacteria,1MWZT@1224|Proteobacteria,2VIFM@28216|Betaproteobacteria,2KV4T@206389|Rhodocyclales	206389|Rhodocyclales	T	Type IV pili methyl-accepting chemotaxis transducer N-term	-	-	2.7.13.3	ko:K07673	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF_2,HAMP,HATPase_c,HisKA_3,PilJ
CH2_k127_2853074_2	76114.ebA6278	3.274e-88	301.0	COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria,2VMXI@28216|Betaproteobacteria,2KWA5@206389|Rhodocyclales	206389|Rhodocyclales	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K07684	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
CH2_k127_2853074_3	1120999.JONM01000009_gene298	6.599e-18	90.0	2EPJB@1|root,33H5Z@2|Bacteria,1NMAB@1224|Proteobacteria,2VZ2Q@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
CH2_k127_2853074_4	641491.DND132_1108	2.599e-05	49.0	2DI5P@1|root,3023S@2|Bacteria,1PUI9@1224|Proteobacteria,436I7@68525|delta/epsilon subdivisions,2X14K@28221|Deltaproteobacteria,2ME7S@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_2853074_0	1163617.SCD_n00508	1.275e-191	604.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,2VHE8@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
CH2_k127_288327_1	1163617.SCD_n00004	1.01e-99	327.0	COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,2VH4A@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
CH2_k127_288327_0	748280.NH8B_3213	1.212e-135	442.0	COG4394@1|root,COG4394@2|Bacteria,1MYVF@1224|Proteobacteria,2VHIB@28216|Betaproteobacteria,2KPVP@206351|Neisseriales	206351|Neisseriales	S	Uncharacterized protein conserved in bacteria (DUF2331)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2331
CH2_k127_288327_2	296591.Bpro_4256	1.155e-05	48.0	COG1032@1|root,COG1032@2|Bacteria,1Q5NG@1224|Proteobacteria,2VPEG@28216|Betaproteobacteria,4AGU0@80864|Comamonadaceae	28216|Betaproteobacteria	C	Protein of unknown function (DUF4080)	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4080,Radical_SAM
CH2_k127_2982492_6	1123368.AUIS01000018_gene734	1.359e-31	127.0	COG2041@1|root,COG2041@2|Bacteria,1MUW0@1224|Proteobacteria,1RQ2J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	msrP	GO:0000302,GO:0001101,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0016491,GO:0016667,GO:0016672,GO:0016675,GO:0019538,GO:0030091,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0043170,GO:0043546,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0048037,GO:0050662,GO:0050896,GO:0055114,GO:0071704,GO:0097159,GO:1901363,GO:1901530,GO:1901564,GO:1901700	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_molyb
CH2_k127_2982492_0	1163617.SCD_n00189	1.614e-220	693.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,2VI29@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
CH2_k127_2982492_5	1144319.PMI16_02239	7.227e-40	152.0	COG5637@1|root,COG5637@2|Bacteria,1MZY2@1224|Proteobacteria,2VVWE@28216|Betaproteobacteria	28216|Betaproteobacteria	S	polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_2982492_7	1163617.SCD_n00527	2.118e-20	93.0	2EPYJ@1|root,33HJ5@2|Bacteria,1NGGR@1224|Proteobacteria,2W5RM@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_2982492_2	1163617.SCD_n00191	2.126e-121	392.0	COG0744@1|root,COG0744@2|Bacteria,1RDAQ@1224|Proteobacteria,2VHW8@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
CH2_k127_2982492_3	323848.Nmul_A0538	8.237e-113	369.0	COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,2VHHC@28216|Betaproteobacteria,372EY@32003|Nitrosomonadales	28216|Betaproteobacteria	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004764,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009790,GO:0009791,GO:0009793,GO:0009987,GO:0010154,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0055114,GO:0061458,GO:0071704,GO:1901576,GO:1901615	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
CH2_k127_2982492_4	580332.Slit_2921	3.922e-57	203.0	COG0607@1|root,COG0607@2|Bacteria,1REHH@1224|Proteobacteria,2VR3P@28216|Betaproteobacteria,44VYE@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CH2_k127_2982492_1	1163617.SCD_n00193	1.472e-162	520.0	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,2VJ1J@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	czcD1	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
CH2_k127_2982492_8	1163617.SCD_n00194	4.478e-11	63.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,2VHYE@28216|Betaproteobacteria	28216|Betaproteobacteria	E	glutamine synthetase	glnA	GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360	5.4.4.3,6.3.1.2	ko:K01915,ko:K20712	ko00220,ko00250,ko00627,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00627,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253,R06988,R09284	RC00010,RC01754,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
CH2_k127_3010233_0	1163617.SCD_n00341	1.889e-200	634.0	COG0007@1|root,COG1648@1|root,COG0007@2|Bacteria,COG1648@2|Bacteria,1MUI0@1224|Proteobacteria,2VICS@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme	cysG	-	1.3.1.76,2.1.1.107,4.99.1.4	ko:K02302,ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03194,R03947	RC00003,RC00871,RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase
CH2_k127_3049843_1	1163617.SCD_n02102	8.944e-105	348.0	COG3852@1|root,COG3852@2|Bacteria,1QVPN@1224|Proteobacteria,2WH69@28216|Betaproteobacteria	28216|Betaproteobacteria	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	pilS	-	2.7.13.3	ko:K02668	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA
CH2_k127_3049843_0	159087.Daro_0662	5.155e-122	399.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,2KUM4@206389|Rhodocyclales	206389|Rhodocyclales	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	pilR	-	-	ko:K02667	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
CH2_k127_3147706_1	1122604.JONR01000014_gene206	7.063e-130	423.0	COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,1RN0B@1236|Gammaproteobacteria,1X3FB@135614|Xanthomonadales	135614|Xanthomonadales	NU	twitching motility protein	uptC	-	-	ko:K02670	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
CH2_k127_3147706_0	1485544.JQKP01000004_gene468	0.0	1057.0	COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,2VIB1@28216|Betaproteobacteria,44W9C@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	nasA	-	-	ko:K00372	ko00910,ko01120,map00910,map01120	M00531	R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CH2_k127_3147706_5	305700.B447_16632	6.352e-14	76.0	COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,2VIB1@28216|Betaproteobacteria,2KUQZ@206389|Rhodocyclales	206389|Rhodocyclales	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	ko:K00372	ko00910,ko01120,map00910,map01120	M00531	R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CH2_k127_3147706_3	290317.Cpha266_1440	7.204e-34	130.0	COG1598@1|root,COG1598@2|Bacteria	2|Bacteria	N	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_3147706_2	290317.Cpha266_1441	2.998e-39	147.0	COG1724@1|root,COG1724@2|Bacteria	2|Bacteria	N	mRNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
CH2_k127_3147706_6	1163617.SCD_n00293	9.8e-07	53.0	2C5EY@1|root,32YQJ@2|Bacteria,1N8K7@1224|Proteobacteria,2VZ2R@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	DUF4160
CH2_k127_3147706_4	1454004.AW11_00622	4.965e-24	101.0	COG2146@1|root,COG2146@2|Bacteria,1N03R@1224|Proteobacteria,2VSP4@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Nitrite reductase NAD(P)H , small subunit	nirD	-	1.7.1.15	ko:K00363	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,Rieske_2
CH2_k127_3209224_1	1163617.SCD_n02200	4.693e-146	473.0	COG3267@1|root,COG3409@1|root,COG3267@2|Bacteria,COG3409@2|Bacteria,1MU3G@1224|Proteobacteria,2VIK1@28216|Betaproteobacteria	28216|Betaproteobacteria	U	SMART AAA ATPase	exeA	-	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22,PG_binding_1
CH2_k127_3209224_0	1163617.SCD_n00216	1.32e-234	731.0	COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,2VIX5@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate	mpl	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CH2_k127_3301303_0	261292.Nit79A3_0532	9.406e-233	724.0	COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,2VH1A@28216|Betaproteobacteria,3727P@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
CH2_k127_3301303_1	1163617.SCD_n01829	2.956e-41	161.0	COG3133@1|root,COG3133@2|Bacteria,1RK6D@1224|Proteobacteria,2VU04@28216|Betaproteobacteria	28216|Betaproteobacteria	M	17 kDa surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Rick_17kDa_Anti
CH2_k127_3301303_2	1163617.SCD_n00905	1.248e-36	147.0	COG0715@1|root,COG0715@2|Bacteria,1MVZE@1224|Proteobacteria,2VJ88@28216|Betaproteobacteria	28216|Betaproteobacteria	P	ABC-type nitrate sulfonate bicarbonate transport	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
CH2_k127_3362894_1	1163617.SCD_n01581	1.472e-141	458.0	COG2603@1|root,COG2603@2|Bacteria,1N4T5@1224|Proteobacteria,2VIMH@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA	selU	-	-	ko:K06917	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Rhodanese
CH2_k127_3362894_0	1163617.SCD_n01580	3.072e-162	519.0	COG0709@1|root,COG0709@2|Bacteria,1MWFG@1224|Proteobacteria,2VJSD@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C,Pyr_redox_2
CH2_k127_3362894_2	1163617.SCD_n01579	1.964e-101	334.0	COG0745@1|root,COG0745@2|Bacteria,1MU67@1224|Proteobacteria,2VKKV@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Transcriptional regulator	ragA	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
CH2_k127_3362894_4	1163617.SCD_n01578	3.871e-71	255.0	COG0642@1|root,COG2205@2|Bacteria,1MXH7@1224|Proteobacteria,2VHKW@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
CH2_k127_3362894_6	1163617.SCD_n01577	5.551e-66	235.0	COG2755@1|root,COG2755@2|Bacteria,1RCXZ@1224|Proteobacteria,2VRIQ@28216|Betaproteobacteria	28216|Betaproteobacteria	E	PFAM lipolytic protein G-D-S-L family	tesA	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL_2
CH2_k127_3362894_3	1131553.JIBI01000008_gene1319	1.84e-90	304.0	COG4181@1|root,COG4181@2|Bacteria,1MXG9@1224|Proteobacteria,2VI54@28216|Betaproteobacteria,3722E@32003|Nitrosomonadales	28216|Betaproteobacteria	Q	ABC transporter	lolD	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CH2_k127_3362894_5	1163617.SCD_n01575	5.433e-69	242.0	COG3127@1|root,COG3127@2|Bacteria,1MU9R@1224|Proteobacteria,2VHHQ@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	ABC-type transport system involved in lysophospholipase L1 biosynthesis permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CH2_k127_3365685_2	1163617.SCD_n01948	1.365e-163	520.0	COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,2VHJ9@28216|Betaproteobacteria	28216|Betaproteobacteria	S	peptidase U62, modulator of DNA gyrase	tldD	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
CH2_k127_3365685_3	1163617.SCD_n01949	4.482e-155	494.0	COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,2VIR4@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	opaA	-	3.5.5.1	ko:K01501,ko:K11206	ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120	-	R00540,R01887,R03093,R03542,R05591,R07855	RC00315,RC00325,RC00617,RC00959,RC02811	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
CH2_k127_3365685_0	1163617.SCD_n01950	0.0	1325.0	COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,2VH52@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_2,DUF3971
CH2_k127_3365685_1	1163617.SCD_n01957	0.0	1111.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2VIP3@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
CH2_k127_3365685_5	1163617.SCD_n02120	7.722e-69	236.0	COG0735@1|root,COG0735@2|Bacteria,1RH58@1224|Proteobacteria,2VT6I@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Belongs to the Fur family	-	-	-	ko:K09826	-	-	-	-	ko00000,ko03000	-	-	-	FUR
CH2_k127_3365685_7	1395516.PMO01_28730	1.326e-31	125.0	2CEYG@1|root,32S0U@2|Bacteria,1N2NE@1224|Proteobacteria,1SAXV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Ribbon-helix-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	RHH_6
CH2_k127_3365685_6	1395516.PMO01_28725	3.753e-67	230.0	COG1569@1|root,COG1569@2|Bacteria,1RE43@1224|Proteobacteria,1S40R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	nucleic acid-binding protein contains PIN domain	-	-	-	ko:K07063	-	-	-	-	ko00000	-	-	-	PIN_3
CH2_k127_3365685_4	1163617.SCD_n02121	2.87e-76	260.0	COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria	1224|Proteobacteria	E	D-Amino acid dehydrogenase	thiO	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0036094,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043436,GO:0043799,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0072527,GO:0072528,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.4.3.19,1.4.5.1	ko:K00285,ko:K03153	ko00360,ko00730,ko01100,map00360,map00730,map01100	-	R01374,R07463,R09493	RC00006,RC00025,RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
CH2_k127_3370953_2	640081.Dsui_1325	3.875e-92	303.0	COG0494@1|root,COG0494@2|Bacteria,1RDGJ@1224|Proteobacteria,2VIDX@28216|Betaproteobacteria,2KU7I@206389|Rhodocyclales	206389|Rhodocyclales	L	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage	nudH	-	-	ko:K08311	ko03018,map03018	-	R10816	RC00002	ko00000,ko00001,ko01000,ko03019	-	-	-	NUDIX
CH2_k127_3370953_0	1163617.SCD_n02114	1.073e-98	336.0	COG0421@1|root,COG0421@2|Bacteria,1RBWW@1224|Proteobacteria,2VK7S@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Spermidine synthase	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
CH2_k127_3370953_1	1288494.EBAPG3_4100	3.213e-98	323.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,2VGZ9@28216|Betaproteobacteria,371UB@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
CH2_k127_3373124_1	472759.Nhal_1290	4.498e-144	465.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RMU1@1236|Gammaproteobacteria,1WWGW@135613|Chromatiales	135613|Chromatiales	L	TIGRFAM ATP-dependent helicase HrpA	-	-	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
CH2_k127_3373124_10	1163617.SCD_n01903	1.001e-47	172.0	COG2920@1|root,COG2920@2|Bacteria,1RITK@1224|Proteobacteria,2W32H@28216|Betaproteobacteria	28216|Betaproteobacteria	P	DsrC like protein	-	-	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
CH2_k127_3373124_8	1163617.SCD_n01898	2.033e-74	268.0	COG2199@1|root,COG2202@1|root,COG2199@2|Bacteria,COG2202@2|Bacteria,1NWNJ@1224|Proteobacteria,2WHI5@28216|Betaproteobacteria	28216|Betaproteobacteria	T	PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_3,PAS_9
CH2_k127_3373124_3	1163617.SCD_n02225	2.735e-112	365.0	COG0560@1|root,COG0560@2|Bacteria,1RA1A@1224|Proteobacteria,2VMGV@28216|Betaproteobacteria	28216|Betaproteobacteria	E	HAD-superfamily subfamily IB hydrolase, TIGR01490	-	-	-	-	-	-	-	-	-	-	-	-	HAD
CH2_k127_3373124_4	1163617.SCD_n02224	4.882e-106	353.0	COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,2VK1S@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	btuC	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
CH2_k127_3373124_7	1163617.SCD_n02223	1.94e-77	276.0	COG1120@1|root,COG1120@2|Bacteria,1MUNG@1224|Proteobacteria,2VRFJ@28216|Betaproteobacteria	28216|Betaproteobacteria	HP	ABC transporter	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
CH2_k127_3373124_0	1163617.SCD_n02221	1.166e-181	579.0	COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,2VHY5@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control	pcnB	-	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C
CH2_k127_3373124_9	1163617.SCD_n02220	4.105e-61	217.0	COG0801@1|root,COG0801@2|Bacteria,1MZH8@1224|Proteobacteria,2VSE2@28216|Betaproteobacteria	28216|Betaproteobacteria	H	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
CH2_k127_3373124_6	1266925.JHVX01000004_gene1272	1.778e-86	290.0	COG1428@1|root,COG1428@2|Bacteria,1RC50@1224|Proteobacteria,2VQ8U@28216|Betaproteobacteria,372TN@32003|Nitrosomonadales	28216|Betaproteobacteria	F	Deoxynucleoside kinase	dgk	-	-	-	-	-	-	-	-	-	-	-	dNK
CH2_k127_3373124_2	1163617.SCD_n02218	3.36e-119	388.0	COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,2VHZ0@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
CH2_k127_3373124_5	1163617.SCD_n02216	1.96e-101	334.0	COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,2VHF1@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
CH2_k127_3421655_0	697282.Mettu_3162	3.202e-144	483.0	COG0642@1|root,COG2199@1|root,COG2202@1|root,COG3829@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,COG3829@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,Hpt,NMT1,PAS,PAS_3,PAS_4,PAS_9,Response_reg
CH2_k127_3421655_1	1158762.KB898039_gene1707	2.835e-49	181.0	COG0745@1|root,COG0745@2|Bacteria,1MZAS@1224|Proteobacteria,1S9XI@1236|Gammaproteobacteria,1WYTZ@135613|Chromatiales	135613|Chromatiales	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CH2_k127_3421655_2	1158762.KB898039_gene1706	1.24e-28	119.0	COG0642@1|root,COG0683@1|root,COG0745@1|root,COG5002@1|root,COG0683@2|Bacteria,COG0745@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_9,Peripla_BP_6,Response_reg
CH2_k127_3649424_1	1123392.AQWL01000003_gene290	3.129e-274	847.0	COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,2VI3K@28216|Betaproteobacteria,1KSG5@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Inorganic H+ pyrophosphatase	-	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
CH2_k127_3649424_5	1163617.SCD_n01886	5.678e-107	347.0	COG0221@1|root,COG0221@2|Bacteria,1RA2F@1224|Proteobacteria,2VQC0@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
CH2_k127_3649424_6	1163617.SCD_n01885	1.062e-67	234.0	COG0622@1|root,COG0622@2|Bacteria,1RCUQ@1224|Proteobacteria,2VTR8@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
CH2_k127_3649424_2	1163617.SCD_n01884	1.306e-233	728.0	COG1148@1|root,COG1148@2|Bacteria,1Q0ZF@1224|Proteobacteria,2VUBQ@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Glucose inhibited division protein A	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388,ko:K16885	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_oxidored
CH2_k127_3649424_0	1163617.SCD_n01883	0.0	1255.0	COG1148@1|root,COG1908@1|root,COG1148@2|Bacteria,COG1908@2|Bacteria,1MWAG@1224|Proteobacteria,2WEVG@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	ko:K16886	-	-	-	-	ko00000	-	-	-	Fer4,FlpD,Pyr_redox_2
CH2_k127_3649424_4	1163617.SCD_n01882	1.084e-109	357.0	COG1150@1|root,COG1150@2|Bacteria,1RHH3@1224|Proteobacteria,2W0PC@28216|Betaproteobacteria	28216|Betaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K16887	-	-	-	-	ko00000	-	-	-	Fer4_17
CH2_k127_3649424_3	1123392.AQWL01000008_gene1153	3.899e-156	496.0	COG2048@1|root,COG2048@2|Bacteria,1N37J@1224|Proteobacteria,2VV9S@28216|Betaproteobacteria,1KSCV@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Cysteine-rich domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
CH2_k127_3689297_7	1049564.TevJSym_aw00210	1.443e-29	117.0	COG2221@1|root,COG2221@2|Bacteria,1MWY5@1224|Proteobacteria,1RSIM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	TIGRFAM sulfite reductase, dissimilatory-type alpha subunit	dsrA	-	1.8.99.5	ko:K11180	ko00633,ko00920,ko01100,ko01120,map00633,map00920,map01100,map01120	M00596	R00295,R00861,R08035	RC00065,RC01760	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
CH2_k127_3689297_1	1123393.KB891316_gene1850	3.098e-219	682.0	COG2221@1|root,COG2221@2|Bacteria,1MVZQ@1224|Proteobacteria,2VPBV@28216|Betaproteobacteria,1KSR2@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Nitrite and sulphite reductase 4Fe-4S domain	-	-	1.8.99.5	ko:K11181	ko00633,ko00920,ko01100,ko01120,map00633,map00920,map01100,map01120	M00596	R00295,R00861,R08035	RC00065,RC01760	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
CH2_k127_3689297_5	1163617.SCD_n02716	2.936e-59	207.0	COG1553@1|root,COG1553@2|Bacteria,1N021@1224|Proteobacteria,2VR8N@28216|Betaproteobacteria	28216|Betaproteobacteria	P	sulfur relay protein TusD DsrE	-	-	-	ko:K07235	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DrsE
CH2_k127_3689297_3	1163617.SCD_n02715	3.008e-67	230.0	COG2923@1|root,COG2923@2|Bacteria,1N8RV@1224|Proteobacteria,2VSQ5@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Sulfur relay protein TusC DsrF	-	-	-	ko:K07236	ko04122,map04122	-	-	-	ko00000,ko00001,ko03016	-	-	-	DrsE
CH2_k127_3689297_6	1163617.SCD_n02714	7.659e-38	145.0	COG2168@1|root,COG2168@2|Bacteria,1PTT8@1224|Proteobacteria,2VWF4@28216|Betaproteobacteria	28216|Betaproteobacteria	P	DsrH like protein	-	-	-	ko:K07237	ko04122,map04122	-	-	-	ko00000,ko00001,ko03016	-	-	-	DsrH
CH2_k127_3689297_4	1163617.SCD_n02713	2.271e-64	221.0	COG2920@1|root,COG2920@2|Bacteria,1RGVG@1224|Proteobacteria,2VSFJ@28216|Betaproteobacteria	28216|Betaproteobacteria	P	DsrC like protein	-	-	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
CH2_k127_3689297_2	1163617.SCD_n02712	3.203e-125	404.0	COG2181@1|root,COG2181@2|Bacteria,1R48S@1224|Proteobacteria,2VPFB@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Nitrate reductase gamma subunit	-	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_gam
CH2_k127_3689297_0	1163617.SCD_n02711	2.887e-304	936.0	COG0247@1|root,COG0247@2|Bacteria,1NZIG@1224|Proteobacteria,2VNTI@28216|Betaproteobacteria	28216|Betaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
CH2_k127_3689297_8	1163617.SCD_n02710	4.899e-28	114.0	COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1MU2H@1224|Proteobacteria,2VM9R@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_20,Fer4_21,Fer4_7,Pyr_redox_2,Pyr_redox_3
CH2_k127_3699861_0	1163617.SCD_n01841	2.162e-225	702.0	COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,2VI16@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
CH2_k127_3699861_3	267608.RSc1630	3.626e-14	76.0	2E3TT@1|root,32YR7@2|Bacteria,1N9R9@1224|Proteobacteria,2VXA7@28216|Betaproteobacteria,1KA63@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_3699861_1	582744.Msip34_1703	5.115e-115	375.0	COG0428@1|root,COG0428@2|Bacteria,1R40E@1224|Proteobacteria,2VN69@28216|Betaproteobacteria,2KKCZ@206350|Nitrosomonadales	206350|Nitrosomonadales	P	ZIP Zinc transporter	-	-	-	ko:K16267	-	-	-	-	ko00000,ko02000	2.A.5.4.11	-	-	Zip
CH2_k127_3699861_2	1485544.JQKP01000005_gene405	8.842e-37	143.0	COG3713@1|root,COG3713@2|Bacteria,1R5JE@1224|Proteobacteria,2VKVW@28216|Betaproteobacteria,44WAS@713636|Nitrosomonadales	28216|Betaproteobacteria	M	MltA-interacting protein MipA	-	-	-	-	-	-	-	-	-	-	-	-	MipA
CH2_k127_3731862_4	1163617.SCD_n00724	4.335e-32	126.0	COG2885@1|root,COG2885@2|Bacteria,1N6EM@1224|Proteobacteria,2VM27@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Belongs to the ompA family	rmpM	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OMP_b-brl,OmpA,SmpA_OmlA
CH2_k127_3731862_0	1288494.EBAPG3_24400	2.152e-193	612.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,2VJ4R@28216|Betaproteobacteria,37277@32003|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
CH2_k127_3731862_2	748247.AZKH_0391	1.443e-104	364.0	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,EAL,GGDEF,PAS,PAS_4,PAS_9
CH2_k127_3731862_1	580332.Slit_2069	4.84e-115	374.0	COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,2VHGP@28216|Betaproteobacteria,44UZN@713636|Nitrosomonadales	28216|Betaproteobacteria	H	O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway	ubiG	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_23
CH2_k127_3731862_3	1163617.SCD_n01022	1.626e-62	219.0	COG0546@1|root,COG0546@2|Bacteria,1RCXJ@1224|Proteobacteria,2VS13@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Phosphoglycolate phosphatase	gph	-	3.1.3.105	ko:K22292	ko00520,map00520	-	R11785	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
CH2_k127_3788168_2	575540.Isop_3123	3.224e-33	140.0	COG1216@1|root,COG1216@2|Bacteria,2J0FG@203682|Planctomycetes	203682|Planctomycetes	O	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_21
CH2_k127_3788168_1	1266925.JHVX01000005_gene1894	9.976e-136	446.0	2DBH8@1|root,2Z982@2|Bacteria,1MXUE@1224|Proteobacteria,2VP20@28216|Betaproteobacteria,3728K@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
CH2_k127_3788168_0	335283.Neut_0942	3.372e-142	477.0	COG5652@1|root,COG5652@2|Bacteria,1R5TU@1224|Proteobacteria,2WBDW@28216|Betaproteobacteria,3722Q@32003|Nitrosomonadales	28216|Betaproteobacteria	V	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
CH2_k127_3796645_4	582744.Msip34_0269	1.499e-40	150.0	COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,2VI59@28216|Betaproteobacteria,2KKWP@206350|Nitrosomonadales	206350|Nitrosomonadales	E	PFAM Imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
CH2_k127_3796645_2	292415.Tbd_1710	3.852e-101	333.0	COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,2VJPI@28216|Betaproteobacteria,1KT1C@119069|Hydrogenophilales	119069|Hydrogenophilales	E	CobB/CobQ-like glutamine amidotransferase domain	-	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
CH2_k127_3796645_0	1163617.SCD_n00590	2.564e-142	453.0	COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,2VI38@28216|Betaproteobacteria	28216|Betaproteobacteria	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
CH2_k127_3796645_1	1163617.SCD_n00591	1.695e-141	453.0	COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,2VHY0@28216|Betaproteobacteria	28216|Betaproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
CH2_k127_3796645_3	580332.Slit_0629	2.634e-48	175.0	COG0139@1|root,COG0139@2|Bacteria,1MW67@1224|Proteobacteria,2VR9B@28216|Betaproteobacteria,44VV6@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH
CH2_k127_3984384_1	1163617.SCD_n02022	2.883e-156	497.0	COG0651@1|root,COG0651@2|Bacteria,1MXRW@1224|Proteobacteria,2VMAN@28216|Betaproteobacteria	28216|Betaproteobacteria	CP	NADH ubiquinone plastoquinone (Complex I)	hyfB	-	-	-	-	-	-	-	-	-	-	-	Proton_antipo_M
CH2_k127_3984384_0	1163617.SCD_n02021	0.0	1019.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,2VHKJ@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Sulfate transporter antisigma-factor antagonist STAS	-	-	-	-	-	-	-	-	-	-	-	-	STAS,Sulfate_transp
CH2_k127_4022905_0	1163617.SCD_n00279	0.0	1471.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU43@1224|Proteobacteria,2VHYU@28216|Betaproteobacteria	28216|Betaproteobacteria	C	FAD linked oxidase domain protein	glpCD	-	-	-	-	-	-	-	-	-	-	-	CCG,DUF3400,DUF3683,FAD-oxidase_C,FAD_binding_4,Fer4_8
CH2_k127_4022905_1	1163617.SCD_n00280	5.041e-54	191.0	COG0537@1|root,COG0537@2|Bacteria,1MZVD@1224|Proteobacteria,2VU7S@28216|Betaproteobacteria	28216|Betaproteobacteria	FG	Histidine triad (Hit) protein	hit	-	-	-	-	-	-	-	-	-	-	-	HIT
CH2_k127_41086_0	1163617.SCD_n00082	3.77e-145	466.0	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,2VPGP@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	rnfF	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
CH2_k127_41086_1	321332.CYB_0917	8.934e-97	327.0	COG3437@1|root,COG3437@2|Bacteria	2|Bacteria	T	response regulator, receiver	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
CH2_k127_41086_3	880073.Calab_3540	2.526e-18	91.0	COG2204@1|root,COG2204@2|Bacteria,2NRGX@2323|unclassified Bacteria	2|Bacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HisKA,PAS_3,Response_reg
CH2_k127_41086_2	326427.Cagg_0841	1.361e-31	135.0	COG0745@1|root,COG2198@1|root,COG2199@1|root,COG0745@2|Bacteria,COG2198@2|Bacteria,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	rcsD	GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009927,GO:0009987,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0031224,GO:0031226,GO:0035556,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0071704,GO:0071944,GO:0140096,GO:1901564	2.7.13.3,2.7.7.65,4.6.1.1	ko:K01768,ko:K02488,ko:K07676,ko:K10715,ko:K20976	ko00230,ko02020,ko02024,ko02025,ko02026,ko04112,ko04113,ko04213,map00230,map02020,map02024,map02025,map02026,map04112,map04113,map04213	M00474,M00511,M00517,M00695,M00820	R00089,R00434,R08057	RC00295	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GGDEF,HATPase_c,HisKA,Hpt,RcsD_ABL,Response_reg,Trans_reg_C
CH2_k127_4126925_1	265072.Mfla_2457	1.651e-173	552.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,2VHY4@28216|Betaproteobacteria,2KKNT@206350|Nitrosomonadales	206350|Nitrosomonadales	U	type II and III secretion system protein	-	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
CH2_k127_4126925_3	1163617.SCD_n02946	6.408e-75	255.0	COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,2VRDN@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
CH2_k127_4126925_0	1163617.SCD_n02947	1.001e-174	554.0	COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,2VHXR@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
CH2_k127_4126925_2	522306.CAP2UW1_4182	3.677e-94	312.0	COG0232@1|root,COG0232@2|Bacteria,1MVQ2@1224|Proteobacteria,2VI7B@28216|Betaproteobacteria,1KPTA@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	F	Belongs to the dGTPase family. Type 2 subfamily	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
CH2_k127_4160169_13	1163617.SCD_n00197	9.583e-48	173.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria	28216|Betaproteobacteria	T	response regulator	ntrC	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CH2_k127_4160169_8	1163617.SCD_n01879	3.684e-98	330.0	COG5544@1|root,COG5544@2|Bacteria,1R35W@1224|Proteobacteria,2VR90@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Predicted periplasmic lipoprotein (DUF2279)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2279
CH2_k127_4160169_5	1163617.SCD_n00201	6.426e-128	415.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,2VH7N@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Exodeoxyribonuclease III	xthA	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
CH2_k127_4160169_17	582744.Msip34_1217	1.201e-29	124.0	COG5488@1|root,COG5488@2|Bacteria,1N5Z9@1224|Proteobacteria,2VU1W@28216|Betaproteobacteria,2KN5A@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Integral membrane protein (DUF2244)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2244
CH2_k127_4160169_1	1163617.SCD_n02661	1.625e-188	595.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,1MWHZ@1224|Proteobacteria,2VH9M@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	coxB	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrome_CBB3,OmpA
CH2_k127_4160169_0	159087.Daro_1470	1.401e-312	961.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,2VHGU@28216|Betaproteobacteria,2KVEH@206389|Rhodocyclales	206389|Rhodocyclales	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
CH2_k127_4160169_12	522306.CAP2UW1_4153	1.565e-52	192.0	COG3175@1|root,COG3175@2|Bacteria,1RDTU@1224|Proteobacteria,2VHRQ@28216|Betaproteobacteria,1KQT5@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	O	Cytochrome c oxidase assembly protein CtaG/Cox11	ctaG	-	-	ko:K02258	ko00190,ko01100,ko04714,map00190,map01100,map04714	M00154	-	-	ko00000,ko00001,ko00002,ko03029	3.D.4.8	-	-	CtaG_Cox11
CH2_k127_4160169_2	1163617.SCD_n02658	3.69e-149	475.0	COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,2VJAP@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome c oxidase subunit III	coxC	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
CH2_k127_4160169_9	1163617.SCD_n02656	1.104e-70	246.0	COG3346@1|root,COG3346@2|Bacteria,1MZUH@1224|Proteobacteria,2VSAZ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	SURF1-like protein	surf1	-	-	ko:K14998	-	-	-	-	ko00000,ko03029	3.D.4.8	-	-	SURF1
CH2_k127_4160169_14	1163617.SCD_n02655	1.883e-43	166.0	COG1999@1|root,COG1999@2|Bacteria,1RHK3@1224|Proteobacteria,2VRBY@28216|Betaproteobacteria	28216|Betaproteobacteria	S	signal sequence binding	sco1	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_4160169_4	1163617.SCD_n02654	1.025e-133	436.0	COG0109@1|root,COG0109@2|Bacteria,1MW3S@1224|Proteobacteria,2VHZU@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
CH2_k127_4160169_10	1163617.SCD_n02594	4.375e-59	210.0	2ECQ3@1|root,336MT@2|Bacteria,1NB5U@1224|Proteobacteria,2VVY5@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_4160169_6	1163617.SCD_n00522	1.777e-117	379.0	COG0302@1|root,COG0302@2|Bacteria,1MY3N@1224|Proteobacteria,2VH10@28216|Betaproteobacteria	28216|Betaproteobacteria	H	GTP cyclohydrolase	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
CH2_k127_4160169_16	76114.ebB107	6.341e-34	134.0	2C78Q@1|root,331C6@2|Bacteria,1N873@1224|Proteobacteria,2VU4C@28216|Betaproteobacteria,2KZB4@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein  of unknown function (DUF3018)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3018
CH2_k127_4160169_11	317013.NY99_21715	1.567e-54	192.0	COG2337@1|root,COG2337@2|Bacteria,1MZAV@1224|Proteobacteria,1S7ZM@1236|Gammaproteobacteria,1X7RE@135614|Xanthomonadales	135614|Xanthomonadales	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
CH2_k127_4160169_15	1163617.SCD_n00524	6.703e-35	138.0	2E4IS@1|root,32ZDU@2|Bacteria,1N7N3@1224|Proteobacteria,2VVSI@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM PsiF repeat protein	psiF	-	-	-	-	-	-	-	-	-	-	-	PsiF_repeat
CH2_k127_4160169_7	1163617.SCD_n00530	8.784e-109	357.0	COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,2VJN2@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	-	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
CH2_k127_4160169_3	1163617.SCD_n00531	2.006e-143	457.0	COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,2VJ8T@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
CH2_k127_4255692_4	1163617.SCD_n02533	1.322e-67	233.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,2VI2V@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
CH2_k127_4255692_1	292415.Tbd_2229	5.023e-100	330.0	COG0546@1|root,COG0546@2|Bacteria,1RDDY@1224|Proteobacteria,2VIZ6@28216|Betaproteobacteria,1KRSC@119069|Hydrogenophilales	119069|Hydrogenophilales	G	HAD-hyrolase-like	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
CH2_k127_4255692_0	1163617.SCD_n02535	1.372e-133	428.0	COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,2VIGU@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
CH2_k127_4255692_5	1163617.SCD_n02536	9.811e-62	215.0	COG2967@1|root,COG2967@2|Bacteria,1MZ2Z@1224|Proteobacteria,2VSPE@28216|Betaproteobacteria	28216|Betaproteobacteria	P	PFAM ApaG domain protein	apaG	-	-	ko:K06195	-	-	-	-	ko00000	-	-	-	DUF525
CH2_k127_4255692_2	292415.Tbd_0886	2.357e-83	287.0	COG3118@1|root,COG3118@2|Bacteria,1NWGI@1224|Proteobacteria,2W360@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Tetratricopeptide repeat	-	-	-	ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
CH2_k127_4255692_7	335283.Neut_0222	1.103e-07	57.0	2AFRM@1|root,315TK@2|Bacteria,1PW6N@1224|Proteobacteria,2WBRN@28216|Betaproteobacteria,373P1@32003|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_4255692_6	713586.KB900536_gene1430	1.491e-19	89.0	2E4UA@1|root,32ZNM@2|Bacteria,1NAZR@1224|Proteobacteria,1SC82@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_4255692_3	1131553.JIBI01000025_gene152	2.598e-74	258.0	28P0I@1|root,2ZBX5@2|Bacteria,1RB8U@1224|Proteobacteria,2VQ6K@28216|Betaproteobacteria,37331@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF3025)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3025
CH2_k127_4256801_1	1485544.JQKP01000021_gene44	4.573e-142	454.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,2VIF3@28216|Betaproteobacteria,44VNH@713636|Nitrosomonadales	28216|Betaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
CH2_k127_4256801_3	1163617.SCD_n00620	1.002e-68	235.0	COG0048@1|root,COG0048@2|Bacteria,1RCWY@1224|Proteobacteria,2VR2H@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
CH2_k127_4256801_2	1288494.EBAPG3_9610	2.346e-76	258.0	COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,2VQ63@28216|Betaproteobacteria,372P2@32003|Nitrosomonadales	28216|Betaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
CH2_k127_4256801_0	1163617.SCD_n00622	0.0	1379.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,2VI3Q@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
CH2_k127_4256801_4	1165096.ARWF01000001_gene1251	3.034e-19	87.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,2VH5D@28216|Betaproteobacteria,2KKR0@206350|Nitrosomonadales	206350|Nitrosomonadales	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
CH2_k127_4258983_17	1163617.SCD_n02061	5.302e-25	106.0	2E2DR@1|root,32XIE@2|Bacteria,1N271@1224|Proteobacteria,2W4PR@28216|Betaproteobacteria	28216|Betaproteobacteria	S	SseB protein N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	SseB
CH2_k127_4258983_6	626887.J057_07216	2.679e-103	372.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,4667H@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,HATPase_c,HisKA,Hpt,PAS,PAS_4,PAS_8,PAS_9,Response_reg,TPR_12,TPR_7,TPR_8
CH2_k127_4258983_14	748247.AZKH_0194	1.066e-35	146.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KVEE@206389|Rhodocyclales	206389|Rhodocyclales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,Response_reg
CH2_k127_4258983_1	1163617.SCD_n02069	5.114e-191	603.0	COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,2VKNG@28216|Betaproteobacteria	28216|Betaproteobacteria	J	SMART PUA domain containing protein	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
CH2_k127_4258983_15	159087.Daro_0219	2.677e-35	138.0	COG0640@1|root,COG0640@2|Bacteria,1RBZC@1224|Proteobacteria,2VR13@28216|Betaproteobacteria,2KW3M@206389|Rhodocyclales	206389|Rhodocyclales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_4258983_19	713586.KB900536_gene1873	5.028e-12	68.0	COG5481@1|root,COG5481@2|Bacteria,1QB94@1224|Proteobacteria,1SHNI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF465)	-	-	-	-	-	-	-	-	-	-	-	-	DUF465
CH2_k127_4258983_18	1163617.SCD_n02059	1.764e-20	94.0	2CHG9@1|root,3332K@2|Bacteria,1NCD5@1224|Proteobacteria,2VWRB@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_4258983_11	1163617.SCD_n02057	1.799e-58	205.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,2VSIG@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Peptidyl-prolyl cis-trans isomerase	fkpA	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
CH2_k127_4258983_9	926560.KE387026_gene4222	8.209e-64	224.0	29A26@1|root,2ZX3K@2|Bacteria,1WMUP@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_4258983_5	1163617.SCD_n01940	1.504e-112	370.0	COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,2VINY@28216|Betaproteobacteria	28216|Betaproteobacteria	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
CH2_k127_4258983_12	261292.Nit79A3_0354	5.862e-48	174.0	COG2154@1|root,COG2154@2|Bacteria,1MZ5Q@1224|Proteobacteria,2VVZF@28216|Betaproteobacteria,373A7@32003|Nitrosomonadales	28216|Betaproteobacteria	H	diol metabolic process	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
CH2_k127_4258983_16	1123392.AQWL01000001_gene1593	1.144e-34	135.0	COG2010@1|root,COG2010@2|Bacteria,1N71Z@1224|Proteobacteria,2VWE5@28216|Betaproteobacteria,1KT8P@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_4258983_4	1131553.JIBI01000016_gene616	4.932e-172	549.0	COG0501@1|root,COG0501@2|Bacteria,1MUXT@1224|Proteobacteria,2VI1Y@28216|Betaproteobacteria,372MW@32003|Nitrosomonadales	28216|Betaproteobacteria	O	PFAM Peptidase M48	htpX_2	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
CH2_k127_4258983_7	580332.Slit_1043	1.939e-96	317.0	COG1949@1|root,COG1949@2|Bacteria,1R9WX@1224|Proteobacteria,2VIA2@28216|Betaproteobacteria,44VDX@713636|Nitrosomonadales	28216|Betaproteobacteria	L	3'-to-5' exoribonuclease specific for small oligoribonucleotides	orn	-	-	ko:K13288	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	RNase_T
CH2_k127_4258983_13	1182590.BN5_00490	3.513e-43	163.0	COG3577@1|root,COG3577@2|Bacteria,1N2PE@1224|Proteobacteria,1S60F@1236|Gammaproteobacteria,1YG59@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	gag-polyprotein putative aspartyl protease	orf	-	-	ko:K06985	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	gag-asp_proteas
CH2_k127_4258983_0	1163617.SCD_n01935	0.0	1341.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,2VM4W@28216|Betaproteobacteria	28216|Betaproteobacteria	G	alpha-glucan phosphorylase	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
CH2_k127_4258983_8	522306.CAP2UW1_0659	3.459e-66	234.0	COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,2VM6F@28216|Betaproteobacteria	28216|Betaproteobacteria	T	protein phosphatase 2C domain protein	pppL	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
CH2_k127_4258983_10	580332.Slit_0800	3.166e-63	219.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,2VR2Z@28216|Betaproteobacteria,44VVD@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
CH2_k127_4258983_3	582744.Msip34_2486	2.06e-173	556.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,2VITN@28216|Betaproteobacteria,2KM0B@206350|Nitrosomonadales	206350|Nitrosomonadales	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
CH2_k127_4258983_2	1163617.SCD_n00652	2.045e-177	558.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,2VIJE@28216|Betaproteobacteria	28216|Betaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
CH2_k127_4259351_0	1123392.AQWL01000011_gene2256	1.868e-218	683.0	COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,2VINP@28216|Betaproteobacteria,1KRWZ@119069|Hydrogenophilales	119069|Hydrogenophilales	E	ACT domain	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
CH2_k127_4259351_1	1123392.AQWL01000011_gene2255	4.3e-202	639.0	COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,2VHJ8@28216|Betaproteobacteria,1KS9R@119069|Hydrogenophilales	119069|Hydrogenophilales	J	tRNA (Uracil-5-)-methyltransferase	-	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
CH2_k127_4259351_2	1123392.AQWL01000011_gene2254	5.396e-122	396.0	COG3298@1|root,COG3298@2|Bacteria,1MVZJ@1224|Proteobacteria,2VISP@28216|Betaproteobacteria,1KRCC@119069|Hydrogenophilales	119069|Hydrogenophilales	L	Predicted 3'-5' exonuclease related to the exonuclease domain of PolB	-	-	-	ko:K07501	-	-	-	-	ko00000	-	-	-	DNA_pol_B_exo2
CH2_k127_4259351_3	1123392.AQWL01000011_gene2253	8.325e-43	166.0	COG3434@1|root,COG3434@2|Bacteria,1PW8X@1224|Proteobacteria,2WBU0@28216|Betaproteobacteria,1KSJM@119069|Hydrogenophilales	119069|Hydrogenophilales	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
CH2_k127_4261169_18	1132855.KB913035_gene1399	3.46e-09	61.0	COG4970@1|root,COG4970@2|Bacteria,1N8HW@1224|Proteobacteria,2VWJK@28216|Betaproteobacteria,2KN45@206350|Nitrosomonadales	206350|Nitrosomonadales	NU	Tfp pilus assembly protein FimT	-	-	-	ko:K10926	ko05111,map05111	-	-	-	ko00000,ko00001,ko02044	-	-	-	GspH,N_methyl
CH2_k127_4261169_14	338969.Rfer_3340	1.954e-34	138.0	COG4967@1|root,COG4967@2|Bacteria,1RKKA@1224|Proteobacteria,2VTQ8@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	type IV pilus modification protein PilV	-	-	-	ko:K10927	ko05111,map05111	-	-	-	ko00000,ko00001,ko02044	-	-	-	N_methyl
CH2_k127_4261169_7	292415.Tbd_0757	9.146e-63	228.0	COG2165@1|root,COG2165@2|Bacteria,1RHHG@1224|Proteobacteria,2VT5N@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	prepilin-type N-terminal cleavage methylation	-	-	-	ko:K12285	-	-	-	-	ko00000,ko02044	-	-	-	N_methyl
CH2_k127_4261169_16	666681.M301_1275	1.315e-29	124.0	COG4726@1|root,COG4726@2|Bacteria,1N9C7@1224|Proteobacteria,2VWCD@28216|Betaproteobacteria,2KN39@206350|Nitrosomonadales	206350|Nitrosomonadales	NU	Pilus assembly protein PilX	-	-	-	ko:K12286	-	-	-	-	ko00000,ko02044	-	-	-	-
CH2_k127_4261169_2	1095769.CAHF01000013_gene3394	8.368e-148	506.0	COG1664@1|root,COG1664@2|Bacteria,1QUZJ@1224|Proteobacteria,2WGN3@28216|Betaproteobacteria,47924@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Polymer-forming cytoskeletal	-	-	-	ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	-
CH2_k127_4261169_5	1095769.CAHF01000011_gene2530	1.015e-105	351.0	COG4972@1|root,COG4972@2|Bacteria,1N0HS@1224|Proteobacteria,2VQYY@28216|Betaproteobacteria,473FM@75682|Oxalobacteraceae	28216|Betaproteobacteria	NU	Pilus assembly protein	-	-	-	ko:K12279	-	-	-	-	ko00000,ko02044	-	-	-	PilM_2
CH2_k127_4261169_10	1095769.CAHF01000011_gene2529	4.449e-57	205.0	COG3166@1|root,COG3166@2|Bacteria,1RHH0@1224|Proteobacteria,2VSNK@28216|Betaproteobacteria,478UQ@75682|Oxalobacteraceae	28216|Betaproteobacteria	NU	PFAM Fimbrial assembly family protein	-	-	-	-	-	-	-	-	-	-	-	-	PilN
CH2_k127_4261169_11	1095769.CAHF01000011_gene2528	3.993e-55	200.0	COG3167@1|root,COG3167@2|Bacteria,1N1KE@1224|Proteobacteria,2VV3H@28216|Betaproteobacteria,474M0@75682|Oxalobacteraceae	28216|Betaproteobacteria	NU	carbon utilization	-	-	-	ko:K12280	-	-	-	-	ko00000,ko02044	-	-	-	T2SSM
CH2_k127_4261169_17	204773.HEAR1940	4.784e-16	82.0	2DR7A@1|root,33AIK@2|Bacteria,1NGEC@1224|Proteobacteria,2VY5Y@28216|Betaproteobacteria,4759Q@75682|Oxalobacteraceae	28216|Betaproteobacteria	-	-	-	-	-	ko:K12281	-	-	-	-	ko00000,ko02044	-	-	-	-
CH2_k127_4261169_1	1163617.SCD_n02671	6.863e-200	640.0	COG1450@1|root,COG4796@1|root,COG1450@2|Bacteria,COG4796@2|Bacteria,1MVNC@1224|Proteobacteria,2VMZA@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	type II and III secretion system protein	-	-	-	ko:K02453,ko:K12282	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	STN,Secretin,Secretin_N_2
CH2_k127_4261169_4	1095769.CAHF01000011_gene2526	4.034e-128	416.0	COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,2VKIQ@28216|Betaproteobacteria,472K4@75682|Oxalobacteraceae	28216|Betaproteobacteria	U	AAA domain	exeA2	-	-	ko:K02450,ko:K12283	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22
CH2_k127_4261169_6	1095769.CAHF01000011_gene2525	7.067e-70	251.0	COG0457@1|root,COG0457@2|Bacteria,1N260@1224|Proteobacteria,2VTG6@28216|Betaproteobacteria,478VR@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Tetratricopeptide repeat	-	-	-	ko:K12284	-	-	-	-	ko00000,ko02044	-	-	-	TPR_16,TPR_19,TPR_4,TPR_8
CH2_k127_4261169_3	1163617.SCD_n02688	4.838e-129	422.0	COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,2VJ91@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
CH2_k127_4261169_13	1163617.SCD_n02689	7.043e-41	158.0	COG3807@1|root,COG3807@2|Bacteria,1MZIA@1224|Proteobacteria,2VUTD@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Bacterial SH3 domain	-	-	-	-	-	-	-	-	-	-	-	-	SH3_4
CH2_k127_4261169_8	292415.Tbd_2402	2.13e-62	218.0	COG1952@1|root,COG1952@2|Bacteria,1RI75@1224|Proteobacteria,2VQ1Q@28216|Betaproteobacteria,1KSVW@119069|Hydrogenophilales	119069|Hydrogenophilales	U	Preprotein translocase subunit SecB	-	-	-	ko:K03071	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03110	3.A.5	-	-	SecB
CH2_k127_4261169_9	1163617.SCD_n02691	2.647e-60	212.0	COG3118@1|root,COG3118@2|Bacteria,1RHUA@1224|Proteobacteria,2VR2G@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Thioredoxin	trxC	-	1.8.1.8	ko:K03672	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Thioredoxin
CH2_k127_4261169_15	1175306.GWL_43410	3.042e-34	133.0	COG0695@1|root,COG0695@2|Bacteria,1N72P@1224|Proteobacteria,2VU2J@28216|Betaproteobacteria,474TH@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	grxC	-	-	ko:K03676	-	-	-	-	ko00000,ko03110	-	-	-	Glutaredoxin
CH2_k127_4261169_12	1123393.KB891316_gene1738	3.443e-45	167.0	COG0607@1|root,COG0607@2|Bacteria,1MZ83@1224|Proteobacteria,2VU3D@28216|Betaproteobacteria,1KRUK@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CH2_k127_4261169_0	1123487.KB892863_gene1946	4.366e-254	798.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VI3F@28216|Betaproteobacteria,2KUP6@206389|Rhodocyclales	206389|Rhodocyclales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
CH2_k127_4306670_4	1095769.CAHF01000010_gene1288	1.136e-27	114.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,2VHBB@28216|Betaproteobacteria,47263@75682|Oxalobacteraceae	28216|Betaproteobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	hemN2	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
CH2_k127_4306670_5	565033.GACE_0288	1.572e-23	108.0	COG1553@1|root,arCOG02068@2157|Archaea,2Y6XQ@28890|Euryarchaeota,2478Y@183980|Archaeoglobi	183980|Archaeoglobi	P	DsrE/DsrF-like family	-	-	-	ko:K06039	-	-	-	-	ko00000	-	-	-	DrsE
CH2_k127_4306670_1	697282.Mettu_3160	3.766e-85	306.0	COG2202@1|root,COG5000@1|root,COG5002@1|root,COG2202@2|Bacteria,COG5000@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1T1JE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GAF_2,GGDEF,HAMP,HATPase_c,HTH_18,HisKA,Hpt,MASE1,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Phosphonate-bd,Reg_prop,Response_reg,TarH,Y_Y_Y
CH2_k127_4306670_3	1163617.SCD_n00202	2.534e-38	150.0	COG0695@1|root,COG0695@2|Bacteria,1N7X3@1224|Proteobacteria,2VVPB@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Pfam Glutaredoxin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124,Glutaredoxin
CH2_k127_4306670_0	1163617.SCD_n00204	0.0	1069.0	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,2VHPQ@28216|Betaproteobacteria	28216|Betaproteobacteria	E	PFAM peptidase M3A and M3B, thimet oligopeptidase F	prlC	-	3.4.24.70	ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
CH2_k127_4306670_2	292415.Tbd_2432	6.534e-70	241.0	COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,2VR65@28216|Betaproteobacteria,1KRRP@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
CH2_k127_4306670_7	1123400.KB904751_gene895	8.172e-05	47.0	COG3503@1|root,COG3503@2|Bacteria,1RA1Q@1224|Proteobacteria,1SAPP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
CH2_k127_4325348_4	1163617.SCD_n02014	1.528e-17	82.0	COG0607@1|root,COG0607@2|Bacteria,1NBYS@1224|Proteobacteria	1224|Proteobacteria	P	Rhodanese domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CH2_k127_4325348_2	1163617.SCD_n02013	2.51e-76	260.0	COG4275@1|root,COG4275@2|Bacteria,1MYDE@1224|Proteobacteria,2VQ0S@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Chromate resistance exported protein	-	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist
CH2_k127_4325348_1	1163617.SCD_n02330	9.14e-92	304.0	COG3803@1|root,COG3803@2|Bacteria,1RHYI@1224|Proteobacteria,2VSHT@28216|Betaproteobacteria	28216|Betaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF924
CH2_k127_4325348_3	1163407.UU7_12004	6.819e-60	211.0	COG3476@1|root,COG3476@2|Bacteria,1MZC1@1224|Proteobacteria,1SCEH@1236|Gammaproteobacteria,1X7CI@135614|Xanthomonadales	135614|Xanthomonadales	T	Tryptophan-rich sensory protein	tspO	-	-	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	-	-	-	ko00000,ko00001,ko02000	9.A.24	-	-	TspO_MBR
CH2_k127_4325348_0	305700.B447_00655	2.761e-105	347.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2VHGM@28216|Betaproteobacteria,2KVQ7@206389|Rhodocyclales	206389|Rhodocyclales	P	Belongs to the ABC transporter superfamily	-	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
CH2_k127_4418780_1	1163617.SCD_n02706	1.772e-205	647.0	COG1797@1|root,COG1797@2|Bacteria,1MV7Z@1224|Proteobacteria,2VI93@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source	cbiA	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	AAA_26,CbiA,GATase_3
CH2_k127_4418780_2	1163617.SCD_n02705	9.013e-30	123.0	COG0316@1|root,COG0316@2|Bacteria,1N8ZN@1224|Proteobacteria,2W5FR@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Iron-sulphur cluster biosynthesis	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
CH2_k127_4418780_0	1163617.SCD_n02704	5.932e-214	673.0	COG1249@1|root,COG1249@2|Bacteria,1RB5F@1224|Proteobacteria	1224|Proteobacteria	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	lpdA_2	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
CH2_k127_4432607_2	1095769.CAHF01000011_gene2538	2.71e-37	143.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,2VJ2Y@28216|Betaproteobacteria,473HH@75682|Oxalobacteraceae	28216|Betaproteobacteria	NU	Type II secretion system (T2SS), protein F	pilC3	-	-	ko:K02455,ko:K12278	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
CH2_k127_4432607_1	105559.Nwat_0046	2.72e-41	156.0	COG0399@1|root,COG0399@2|Bacteria,1N0QW@1224|Proteobacteria,1S8YK@1236|Gammaproteobacteria,1X28T@135613|Chromatiales	135613|Chromatiales	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
CH2_k127_4432607_0	1095769.CAHF01000011_gene2539	2.455e-234	729.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria,47316@75682|Oxalobacteraceae	28216|Betaproteobacteria	NU	Type II secretion system (T2SS), protein E, N-terminal domain	-	-	-	ko:K02454,ko:K12276	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
CH2_k127_4662058_1	760117.JN27_02260	1.284e-106	353.0	COG0451@1|root,COG0451@2|Bacteria,1MWVJ@1224|Proteobacteria,2VJ3T@28216|Betaproteobacteria,473J1@75682|Oxalobacteraceae	28216|Betaproteobacteria	GM	RmlD substrate binding domain	yeeZ	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10,RmlD_sub_bind,TrkA_N
CH2_k127_4662058_0	1266925.JHVX01000011_gene1466	2.246e-154	494.0	COG0543@1|root,COG1018@1|root,COG0543@2|Bacteria,COG1018@2|Bacteria,1MV72@1224|Proteobacteria,2VI9K@28216|Betaproteobacteria,372BS@32003|Nitrosomonadales	28216|Betaproteobacteria	C	Oxidoreductase FAD-binding domain	ascD	-	1.17.1.1	ko:K00523	ko00520,map00520	-	R03391,R03392	RC00230	ko00000,ko00001,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
CH2_k127_4662058_2	1163617.SCD_n02795	1.293e-32	128.0	COG3071@1|root,COG3071@2|Bacteria,1MU7A@1224|Proteobacteria,2VK6P@28216|Betaproteobacteria	28216|Betaproteobacteria	H	HemY domain protein	hemY	-	-	ko:K02498	-	-	-	-	ko00000	-	-	-	HemY_N,TPR_12
CH2_k127_4676944_1	1163617.SCD_n02630	1.335e-110	361.0	COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,2VI10@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
CH2_k127_4676944_0	1163617.SCD_n02632	3.867e-311	964.0	COG0699@1|root,COG0699@2|Bacteria,1MXBK@1224|Proteobacteria,2VKA1@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
CH2_k127_4724154_2	1163617.SCD_n01596	2.525e-85	287.0	COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,2VQR7@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Peptidase M22 glycoprotease	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
CH2_k127_4724154_3	1123393.KB891329_gene960	2.3e-37	145.0	COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,2VUIW@28216|Betaproteobacteria,1KRRR@119069|Hydrogenophilales	119069|Hydrogenophilales	K	Acetyltransferase (GNAT) domain	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
CH2_k127_4724154_1	1266925.JHVX01000006_gene2144	3.849e-91	312.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,2VPZQ@28216|Betaproteobacteria,37236@32003|Nitrosomonadales	28216|Betaproteobacteria	L	TIGRFAM Phage SPO1 DNA polymerase-related protein	dpo	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
CH2_k127_4724154_0	1163617.SCD_n01593	3.18e-99	328.0	COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,2VHT5@28216|Betaproteobacteria	28216|Betaproteobacteria	S	LemA Family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
CH2_k127_4724154_4	1122604.JONR01000054_gene4087	1.415e-08	57.0	COG1512@1|root,COG1512@2|Bacteria,1PB41@1224|Proteobacteria,1S38U@1236|Gammaproteobacteria,1XC3C@135614|Xanthomonadales	135614|Xanthomonadales	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
CH2_k127_4730129_1	261292.Nit79A3_3040	1.891e-174	556.0	COG0296@1|root,COG0296@2|Bacteria,1MVM7@1224|Proteobacteria,2W14D@28216|Betaproteobacteria,372WM@32003|Nitrosomonadales	28216|Betaproteobacteria	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
CH2_k127_4730129_0	1163617.SCD_n01925	5.861e-225	702.0	COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,2VIP2@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
CH2_k127_4730129_2	261292.Nit79A3_3042	5.045e-132	431.0	COG1449@1|root,COG1449@2|Bacteria,1P2YJ@1224|Proteobacteria,2VHA4@28216|Betaproteobacteria,372KA@32003|Nitrosomonadales	28216|Betaproteobacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_57
CH2_k127_4743219_1	580332.Slit_2035	3.734e-138	454.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VIW7@28216|Betaproteobacteria	28216|Betaproteobacteria	NT	PilZ domain	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,PilZ
CH2_k127_4743219_4	338969.Rfer_3317	1.99e-24	105.0	2E80T@1|root,332F0@2|Bacteria,1N7RY@1224|Proteobacteria,2VX4M@28216|Betaproteobacteria,4AFZR@80864|Comamonadaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF4389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4389
CH2_k127_4743219_0	1163617.SCD_n02360	1.076e-182	580.0	COG0144@1|root,COG0144@2|Bacteria,1MV2Q@1224|Proteobacteria,2VI1D@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	rsmB_2	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N
CH2_k127_4743219_3	1163617.SCD_n02359	2.138e-69	248.0	COG3170@1|root,COG3170@2|Bacteria,1MWZB@1224|Proteobacteria,2VNBQ@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
CH2_k127_4743219_2	1123354.AUDR01000017_gene110	2.279e-75	256.0	COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,2VJG8@28216|Betaproteobacteria,1KSKC@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Formyl transferase	-	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
CH2_k127_492259_5	582744.Msip34_2525	1.953e-14	73.0	COG2836@1|root,COG2836@2|Bacteria,1RIGJ@1224|Proteobacteria,2VINE@28216|Betaproteobacteria,2KP5N@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2
CH2_k127_492259_0	292415.Tbd_0253	7.805e-246	769.0	COG2271@1|root,COG2271@2|Bacteria,1QUF4@1224|Proteobacteria,2WGXV@28216|Betaproteobacteria,1KSDH@119069|Hydrogenophilales	119069|Hydrogenophilales	G	Acetyl-coenzyme A transporter 1	-	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	MFS_1
CH2_k127_492259_1	1123392.AQWL01000002_gene2016	5.208e-143	456.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,2VI74@28216|Betaproteobacteria,1KS61@119069|Hydrogenophilales	119069|Hydrogenophilales	L	Endonuclease/Exonuclease/phosphatase family	-	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
CH2_k127_492259_2	1163617.SCD_n00092	4.976e-100	329.0	COG0461@1|root,COG0461@2|Bacteria,1MW6F@1224|Proteobacteria,2VH9U@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
CH2_k127_492259_3	1163617.SCD_n00093	7.421e-53	195.0	2DPC5@1|root,331GN@2|Bacteria,1NCRC@1224|Proteobacteria,2VVUT@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF4124)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124
CH2_k127_492259_4	713586.KB900536_gene1636	9.594e-29	118.0	2BVK0@1|root,32QXS@2|Bacteria,1RKSK@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_4957349_6	1347369.CCAD010000036_gene1153	8.684e-54	216.0	COG2202@1|root,COG4191@1|root,COG4585@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,COG4585@2|Bacteria,1VCNJ@1239|Firmicutes,4HVBX@91061|Bacilli,1ZS41@1386|Bacillus	91061|Bacilli	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,MHYT,PAS_9
CH2_k127_4957349_1	1163617.SCD_n00899	2.676e-257	797.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,2VHN4@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
CH2_k127_4957349_0	1163617.SCD_n00898	1e-323	995.0	COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,2VHZX@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Glutaminyl-tRNA synthetase	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
CH2_k127_4957349_3	1163617.SCD_n00897	9.105e-112	372.0	COG0457@1|root,COG0457@2|Bacteria,1Q84V@1224|Proteobacteria,2VJAQ@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	PFAM TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,TPR_11,TPR_16,TPR_17,TPR_19,TPR_8
CH2_k127_4957349_2	1163617.SCD_n00896	6.838e-164	525.0	COG3034@1|root,COG3034@2|Bacteria,1N2B6@1224|Proteobacteria,2VJXB@28216|Betaproteobacteria	28216|Betaproteobacteria	S	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
CH2_k127_4957349_5	1288494.EBAPG3_22210	1.422e-63	224.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,2VQ3Z@28216|Betaproteobacteria,3731S@32003|Nitrosomonadales	28216|Betaproteobacteria	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	-	5.2.1.8	ko:K01802,ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
CH2_k127_4957349_4	582744.Msip34_2253	8.578e-79	268.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,2VQ3Z@28216|Betaproteobacteria,2KMNN@206350|Nitrosomonadales	206350|Nitrosomonadales	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
CH2_k127_4957349_7	583345.Mmol_0506	7.642e-31	124.0	COG2908@1|root,COG2908@2|Bacteria,1N3U7@1224|Proteobacteria,2VQRP@28216|Betaproteobacteria,2KMGY@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxH	-	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Metallophos
CH2_k127_4983696_4	1163617.SCD_n02163	4.046e-91	307.0	COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,2WGST@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	rubB	-	1.18.1.1	ko:K05297,ko:K12265	ko00071,ko05132,map00071,map05132	-	R02000	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
CH2_k127_4983696_5	1123368.AUIS01000009_gene2457	1.282e-57	202.0	COG3118@1|root,COG3118@2|Bacteria,1RHRZ@1224|Proteobacteria,1S8VM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Belongs to the thioredoxin family	trxA3	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
CH2_k127_4983696_0	1121935.AQXX01000107_gene620	3.531e-168	546.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,1XJ24@135619|Oceanospirillales	135619|Oceanospirillales	NU	Type II secretion system (T2SS), protein E, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	T2SSE,T2SSE_N
CH2_k127_4983696_10	1485544.JQKP01000018_gene580	2.724e-10	65.0	COG0666@1|root,COG0666@2|Bacteria,1N952@1224|Proteobacteria,2VTG4@28216|Betaproteobacteria,44VV5@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM Ankyrin	tnkS	-	2.4.2.30	ko:K10799	-	-	-	-	ko00000,ko01000,ko03032,ko03036	-	-	-	Ank,Ank_2,Ank_4
CH2_k127_4983696_2	1163617.SCD_n02324	9.012e-112	368.0	COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,2VHYK@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon	gluQ	-	-	ko:K01894	-	-	-	-	ko00000,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c
CH2_k127_4983696_8	580332.Slit_1668	1.468e-16	85.0	2A8Y3@1|root,30Y1Q@2|Bacteria,1PJWW@1224|Proteobacteria,2W88P@28216|Betaproteobacteria,44WJJ@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_4983696_6	1163617.SCD_n02319	7.78e-43	162.0	2BW2S@1|root,32QYV@2|Bacteria,1RI5M@1224|Proteobacteria,2VX7W@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_4983696_9	1163617.SCD_n02318	2.031e-12	69.0	2EA5W@1|root,334AS@2|Bacteria,1NFAR@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_4983696_1	1163617.SCD_n02317	3.474e-122	403.0	COG1281@1|root,COG1281@2|Bacteria,1MUMU@1224|Proteobacteria,2VI8B@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
CH2_k127_4983696_7	1449350.OCH239_12625	1.104e-37	147.0	COG3600@1|root,COG3600@2|Bacteria,1N78U@1224|Proteobacteria,2UGBJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Phage-associated protein	gepA	-	-	-	-	-	-	-	-	-	-	-	DUF4065
CH2_k127_4983696_3	1485544.JQKP01000001_gene888	4.544e-105	346.0	COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,2VIN7@28216|Betaproteobacteria,44V9E@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Indole-3-glycerol phosphate synthase	trpC	GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
CH2_k127_5066711_3	1458427.BAWN01000015_gene996	4.587e-137	442.0	COG3617@1|root,COG3617@2|Bacteria,1QX1C@1224|Proteobacteria,2WIF0@28216|Betaproteobacteria	28216|Betaproteobacteria	K	BRO family, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Bro-N
CH2_k127_5066711_0	1163617.SCD_n02591	2.966e-216	679.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,2VHQM@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
CH2_k127_5066711_1	1163617.SCD_n02590	4.177e-157	500.0	COG1702@1|root,COG1702@2|Bacteria,1MVDV@1224|Proteobacteria,2VH9V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	PFAM PhoH family protein	ybeZ	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
CH2_k127_5066711_4	497321.C664_04537	7.895e-53	190.0	COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,2VSHV@28216|Betaproteobacteria,2KWFT@206389|Rhodocyclales	206389|Rhodocyclales	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
CH2_k127_5066711_2	1163617.SCD_n02588	8.753e-139	444.0	COG4535@1|root,COG4535@2|Bacteria,1QTU8@1224|Proteobacteria,2VIU8@28216|Betaproteobacteria	28216|Betaproteobacteria	P	CBS domain containing protein	corC	-	-	ko:K06189	-	-	-	-	ko00000,ko02000	9.A.40.1.2	-	-	CBS,CorC_HlyC
CH2_k127_5066711_6	1121440.AUMA01000008_gene942	4.448e-08	58.0	COG0810@1|root,COG0810@2|Bacteria,1NDQZ@1224|Proteobacteria,42VIY@68525|delta/epsilon subdivisions,2WRTC@28221|Deltaproteobacteria,2MDBG@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
CH2_k127_5107586_6	1485544.JQKP01000012_gene2172	2.463e-95	316.0	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,2VIGG@28216|Betaproteobacteria,44V4F@713636|Nitrosomonadales	28216|Betaproteobacteria	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
CH2_k127_5107586_7	1163617.SCD_n03030	1.306e-76	263.0	COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,2VR3B@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
CH2_k127_5107586_3	1163617.SCD_n03029	1.834e-128	415.0	COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,2VHNK@28216|Betaproteobacteria	28216|Betaproteobacteria	D	Cobyrinic acid ac-diamide synthase	parA	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
CH2_k127_5107586_5	1163617.SCD_n03028	1.237e-112	371.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,2VIG0@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
CH2_k127_5107586_11	314278.NB231_10868	5.904e-11	68.0	2DSZ4@1|root,33I02@2|Bacteria,1NGMX@1224|Proteobacteria,1SGFG@1236|Gammaproteobacteria,1X20S@135613|Chromatiales	135613|Chromatiales	S	ATP synthase I chain	-	-	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATP-synt_I
CH2_k127_5107586_2	1163617.SCD_n03026	7.729e-134	430.0	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,2VHR5@28216|Betaproteobacteria	28216|Betaproteobacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
CH2_k127_5107586_10	1163617.SCD_n03025	6.662e-37	140.0	COG0636@1|root,32S3K@2|Bacteria,1N1NA@1224|Proteobacteria,2VTY0@28216|Betaproteobacteria	28216|Betaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
CH2_k127_5107586_8	1163617.SCD_n03024	1.158e-67	233.0	COG0711@1|root,COG0711@2|Bacteria,1RHZ0@1224|Proteobacteria,2VRMS@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
CH2_k127_5107586_9	323848.Nmul_A0307	6.018e-56	200.0	COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,2VSJV@28216|Betaproteobacteria,3737S@32003|Nitrosomonadales	28216|Betaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
CH2_k127_5107586_0	1163617.SCD_n03022	8.517e-297	916.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,2VHQU@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
CH2_k127_5107586_1	1163617.SCD_n03021	3.564e-138	443.0	COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,2VJBW@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
CH2_k127_5107586_4	1163617.SCD_n03020	4.671e-116	377.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,2VHDZ@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
CH2_k127_5139301_0	1163617.SCD_n01850	8.982e-137	451.0	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,2VQUN@28216|Betaproteobacteria	28216|Betaproteobacteria	T	'signal transduction protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
CH2_k127_5139301_3	1123368.AUIS01000008_gene2268	1.934e-20	95.0	COG5569@1|root,COG5569@2|Bacteria,1NGSZ@1224|Proteobacteria,1SGPW@1236|Gammaproteobacteria,2ND1A@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Copper binding periplasmic protein CusF	-	-	-	-	-	-	-	-	-	-	-	-	CusF_Ec
CH2_k127_5139301_2	1502770.JQMG01000001_gene1086	1.673e-107	362.0	COG1538@1|root,COG1538@2|Bacteria,1PCPQ@1224|Proteobacteria,2VMAB@28216|Betaproteobacteria	28216|Betaproteobacteria	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
CH2_k127_5139301_1	1163617.SCD_n01854	4.259e-128	419.0	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,2VJXV@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	cusB	-	-	ko:K07798,ko:K15727	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1,8.A.1.2.1	-	-	CusF_Ec,HlyD_D23
CH2_k127_514447_2	292415.Tbd_1045	3.218e-28	114.0	COG0700@1|root,COG2715@1|root,COG0700@2|Bacteria,COG2715@2|Bacteria,1MVZ0@1224|Proteobacteria,2VKEY@28216|Betaproteobacteria,1KRGF@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Nucleoside recognition	-	-	-	-	-	-	-	-	-	-	-	-	Gate
CH2_k127_514447_0	1163617.SCD_n00389	2.344e-191	608.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,2VI1K@28216|Betaproteobacteria	28216|Betaproteobacteria	FP	PFAM Ppx GppA phosphatase	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
CH2_k127_514447_1	1123392.AQWL01000008_gene1162	1.106e-63	220.0	COG4198@1|root,COG4198@2|Bacteria,1NPPY@1224|Proteobacteria,2VM95@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
CH2_k127_515097_1	1163617.SCD_n02184	5.429e-182	575.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,2VHEB@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Aminotransferase	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CH2_k127_515097_3	292415.Tbd_1852	5.906e-80	269.0	COG3748@1|root,COG3748@2|Bacteria,1RFIZ@1224|Proteobacteria,2VRTS@28216|Betaproteobacteria,1KRXX@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Pfam:DUF989	-	-	-	-	-	-	-	-	-	-	-	-	Urate_ox_N
CH2_k127_515097_5	522306.CAP2UW1_0611	1.178e-30	123.0	COG0454@1|root,COG0456@2|Bacteria,1N7JM@1224|Proteobacteria,2VU1F@28216|Betaproteobacteria,1KR4V@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	K	Protein of unknown function (DUF3579)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3579
CH2_k127_515097_4	640081.Dsui_3254	9.565e-33	130.0	COG0268@1|root,COG0268@2|Bacteria,1MZ94@1224|Proteobacteria,2VTYY@28216|Betaproteobacteria,2KWZ9@206389|Rhodocyclales	206389|Rhodocyclales	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
CH2_k127_515097_0	1163617.SCD_n02133	2.567e-244	763.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,2VHTQ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
CH2_k127_515097_2	1163617.SCD_n02132	1.773e-121	396.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,2VHIP@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
CH2_k127_5158216_3	1163617.SCD_n00872	1.909e-90	302.0	COG0477@1|root,COG2814@2|Bacteria,1MVZI@1224|Proteobacteria,2VHWT@28216|Betaproteobacteria	28216|Betaproteobacteria	EGP	Major facilitator Superfamily	hcaT	-	-	ko:K05820	-	-	-	-	ko00000,ko02000	2.A.1.27	-	-	MFS_1_like
CH2_k127_5158216_0	1163617.SCD_n00873	2.354e-267	827.0	COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,2VHSH@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
CH2_k127_5158216_4	717773.Thicy_0409	1.146e-25	109.0	COG0053@1|root,COG0053@2|Bacteria,1N8A3@1224|Proteobacteria,1SDJW@1236|Gammaproteobacteria,4638J@72273|Thiotrichales	72273|Thiotrichales	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_5158216_2	1163617.SCD_n00874	2.655e-119	386.0	COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,2VIJC@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
CH2_k127_5158216_1	292415.Tbd_1920	1.422e-159	506.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,2VH2M@28216|Betaproteobacteria,1KRIM@119069|Hydrogenophilales	119069|Hydrogenophilales	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
CH2_k127_5160084_7	1163617.SCD_n02149	7.198e-35	141.0	COG0526@1|root,COG0526@2|Bacteria,1N728@1224|Proteobacteria,2VWXC@28216|Betaproteobacteria	28216|Betaproteobacteria	CO	Thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
CH2_k127_5160084_9	443143.GM18_2398	1.161e-22	105.0	COG4273@1|root,COG4273@2|Bacteria,1MZN7@1224|Proteobacteria,42XSN@68525|delta/epsilon subdivisions,2WT4W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF2703)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2703
CH2_k127_5160084_8	1163617.SCD_n02153	1.428e-31	126.0	2EENH@1|root,338GC@2|Bacteria,1N9EC@1224|Proteobacteria,2W4GB@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_5160084_0	1163617.SCD_n02154	3.321e-162	515.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,2VJC7@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
CH2_k127_5160084_2	1255043.TVNIR_0955	1.034e-117	387.0	COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,1RSQ3@1236|Gammaproteobacteria,1WY32@135613|Chromatiales	135613|Chromatiales	P	SMART Rhodanese domain protein	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
CH2_k127_5160084_3	768671.ThimaDRAFT_3701	5.406e-113	372.0	COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,1RSQ3@1236|Gammaproteobacteria,1X0CI@135613|Chromatiales	135613|Chromatiales	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CH2_k127_5160084_1	768671.ThimaDRAFT_3701	6.911e-126	411.0	COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,1RSQ3@1236|Gammaproteobacteria,1X0CI@135613|Chromatiales	135613|Chromatiales	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CH2_k127_5160084_5	1163617.SCD_n02156	2.977e-40	152.0	COG0640@1|root,COG0640@2|Bacteria,1PF11@1224|Proteobacteria,2VXWX@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Bacterial regulatory protein, arsR family	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
CH2_k127_5160084_6	1163617.SCD_n00445	6.487e-40	156.0	2CM31@1|root,32SD0@2|Bacteria,1N2TZ@1224|Proteobacteria,2VUNK@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_5160084_4	580332.Slit_1703	9.363e-47	173.0	COG3439@1|root,COG3439@2|Bacteria,1RHPD@1224|Proteobacteria,2VV5X@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
CH2_k127_516553_0	1163617.SCD_n00889	3.969e-212	664.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,2VJM1@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
CH2_k127_516553_2	1163617.SCD_n01065	6.57e-42	164.0	2EBX9@1|root,335WM@2|Bacteria,1NCDM@1224|Proteobacteria,2VYXB@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_516553_1	1288494.EBAPG3_25350	1.615e-74	252.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,2WGGJ@28216|Betaproteobacteria,371Y6@32003|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	metZ	-	2.5.1.48	ko:K01739,ko:K10764	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
CH2_k127_5186153_0	375286.mma_2648	1.828e-174	562.0	COG0726@1|root,COG1649@1|root,COG0726@2|Bacteria,COG1649@2|Bacteria,1MWR2@1224|Proteobacteria,2VKXV@28216|Betaproteobacteria,474DN@75682|Oxalobacteraceae	28216|Betaproteobacteria	G	Hypothetical glycosyl hydrolase family 13	hmsF	-	-	ko:K11931	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000	-	-	-	GHL13,Polysacc_deac_1
CH2_k127_5186153_1	666681.M301_1739	2.634e-88	322.0	COG0457@1|root,COG0457@2|Bacteria,1RA3P@1224|Proteobacteria,2VRWC@28216|Betaproteobacteria,2KNR7@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Poly-beta-1,6 N-acetyl-D-glucosamine export porin PgaA	-	-	-	ko:K11935	ko02026,map02026	-	-	-	ko00000,ko00001	-	-	-	-
CH2_k127_5197341_3	1163617.SCD_n01778	2.707e-95	320.0	COG1232@1|root,COG1232@2|Bacteria,1NQUH@1224|Proteobacteria,2VJV1@28216|Betaproteobacteria	28216|Betaproteobacteria	H	squalene-associated FAD-dependent desaturase	hpnE	-	1.17.8.1	ko:K21677	-	-	-	-	ko00000,ko01000	-	-	-	Amino_oxidase
CH2_k127_5197341_0	1163617.SCD_n01777	1.13e-125	408.0	COG1562@1|root,COG1562@2|Bacteria,1MX4W@1224|Proteobacteria,2VJ13@28216|Betaproteobacteria	28216|Betaproteobacteria	I	phytoene synthase	hpnD	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
CH2_k127_5197341_1	1163617.SCD_n01776	3.177e-118	385.0	COG1562@1|root,COG1562@2|Bacteria,1N6J2@1224|Proteobacteria,2VIZC@28216|Betaproteobacteria	28216|Betaproteobacteria	I	phytoene synthase	hpnC	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
CH2_k127_5197341_2	261292.Nit79A3_1929	2.333e-109	362.0	COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,2VING@28216|Betaproteobacteria,371ZV@32003|Nitrosomonadales	28216|Betaproteobacteria	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
CH2_k127_5199065_3	1121957.ATVL01000014_gene1443	1.152e-20	93.0	COG5479@1|root,COG5479@2|Bacteria,4P3FJ@976|Bacteroidetes,47V74@768503|Cytophagia	976|Bacteroidetes	M	LGFP repeat	-	-	-	-	-	-	-	-	-	-	-	-	LGFP
CH2_k127_5199065_0	1117958.PE143B_0114060	2.763e-187	598.0	COG3673@1|root,COG3673@2|Bacteria,1NFRW@1224|Proteobacteria,1RP20@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Uncharacterized alpha/beta hydrolase domain (DUF2235)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2235
CH2_k127_5199065_1	472759.Nhal_1734	4.555e-99	330.0	COG5526@1|root,COG5526@2|Bacteria,1RA0A@1224|Proteobacteria,1S4KY@1236|Gammaproteobacteria,1X0T1@135613|Chromatiales	135613|Chromatiales	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_5199065_2	522306.CAP2UW1_2059	1.467e-75	263.0	COG1345@1|root,COG1345@2|Bacteria,1RE6S@1224|Proteobacteria,2VRG1@28216|Betaproteobacteria	28216|Betaproteobacteria	N	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	-	-	-	-	-	-	-	-	-	-	-	-	FliD_C
CH2_k127_5227303_4	1163617.SCD_n01668	2.366e-134	436.0	COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,2VJMF@28216|Betaproteobacteria	28216|Betaproteobacteria	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
CH2_k127_5227303_8	1163617.SCD_n01667	8.635e-92	314.0	COG3115@1|root,COG3115@2|Bacteria,1NJ6D@1224|Proteobacteria,2VHQ7@28216|Betaproteobacteria	28216|Betaproteobacteria	D	Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins	zipA	-	-	-	-	-	-	-	-	-	-	-	ZipA_C
CH2_k127_5227303_0	1163617.SCD_n01666	3.5e-323	1000.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,2VIDE@28216|Betaproteobacteria	28216|Betaproteobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
CH2_k127_5227303_3	159087.Daro_1735	8.794e-139	447.0	COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,2VH00@28216|Betaproteobacteria,2KUS0@206389|Rhodocyclales	206389|Rhodocyclales	M	UTP-glucose-1-phosphate uridylyltransferase	epsT	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
CH2_k127_5227303_9	1163617.SCD_n01664	2.799e-80	271.0	COG0634@1|root,COG0634@2|Bacteria,1NRT8@1224|Proteobacteria,2VQVA@28216|Betaproteobacteria	28216|Betaproteobacteria	F	phosphoribosyltransferase	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
CH2_k127_5227303_6	1163617.SCD_n01661	1.822e-122	396.0	COG0005@1|root,COG0005@2|Bacteria,1MUWW@1224|Proteobacteria,2VJQQ@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage	mtaP	-	2.4.2.28	ko:K00772,ko:K03815	ko00230,ko00270,ko01100,ko01110,map00230,map00270,map01100,map01110	M00034	R01402,R02297	RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
CH2_k127_5227303_7	1163617.SCD_n01660	6.724e-92	304.0	COG0242@1|root,COG0242@2|Bacteria,1R9XK@1224|Proteobacteria,2VQ0U@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def2	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
CH2_k127_5227303_5	1211579.PP4_13890	3.477e-131	421.0	COG1208@1|root,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,1RNWP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	JM	Glucose-1-phosphate cytidylyltransferase	rfbF	-	2.7.7.33	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	-	R00956	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
CH2_k127_5227303_1	395494.Galf_2849	1.386e-155	502.0	COG0451@1|root,COG0451@2|Bacteria,1MV73@1224|Proteobacteria,2VI84@28216|Betaproteobacteria,44W8J@713636|Nitrosomonadales	28216|Betaproteobacteria	M	PFAM NAD-dependent epimerase dehydratase	rfbG	-	4.2.1.45	ko:K01709	ko00520,map00520	-	R02426	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
CH2_k127_5227303_2	395493.BegalDRAFT_2267	5.395e-151	484.0	COG2227@1|root,COG2227@2|Bacteria,1QU62@1224|Proteobacteria,1T2QC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Putative zinc binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_13,Methyltransf_14,Methyltransf_23
CH2_k127_5239454_11	32057.KB217478_gene1481	2.377e-26	111.0	COG2253@1|root,COG2253@2|Bacteria,1GBWG@1117|Cyanobacteria,1HQV5@1161|Nostocales	1117|Cyanobacteria	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
CH2_k127_5239454_0	292415.Tbd_1660	1.625e-202	652.0	COG2199@1|root,COG2200@1|root,COG5000@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,COG5000@2|Bacteria,1RGCV@1224|Proteobacteria,2WGQE@28216|Betaproteobacteria	28216|Betaproteobacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2222,EAL,GGDEF,HAMP
CH2_k127_5239454_10	1163617.SCD_n02076	2.569e-66	237.0	COG2984@1|root,COG2984@2|Bacteria,1NACH@1224|Proteobacteria,2VSU8@28216|Betaproteobacteria	28216|Betaproteobacteria	S	transport system periplasmic component	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
CH2_k127_5239454_2	1163617.SCD_n02078	1.454e-147	492.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,2VH4X@28216|Betaproteobacteria	28216|Betaproteobacteria	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
CH2_k127_5239454_7	1163617.SCD_n01168	1.177e-93	312.0	COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,2VH1Z@28216|Betaproteobacteria	28216|Betaproteobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
CH2_k127_5239454_9	1163617.SCD_n01167	6.984e-70	245.0	COG0328@1|root,COG0328@2|Bacteria,1RCZ1@1224|Proteobacteria,2VR4W@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
CH2_k127_5239454_6	1163617.SCD_n01166	1.539e-99	330.0	COG0500@1|root,COG2226@2|Bacteria,1QTWC@1224|Proteobacteria,2VQ89@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CH2_k127_5239454_5	1163617.SCD_n01165	2.579e-102	338.0	COG0491@1|root,COG0491@2|Bacteria,1MU8Q@1224|Proteobacteria,2VGZG@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	gloB	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	HAGH_C,Lactamase_B
CH2_k127_5239454_1	1163617.SCD_n01164	3.339e-169	548.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,2VIR7@28216|Betaproteobacteria	28216|Betaproteobacteria	M	transglycosylase	mltD	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
CH2_k127_5239454_8	1163617.SCD_n01213	1.191e-88	300.0	COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,2VQ97@28216|Betaproteobacteria	28216|Betaproteobacteria	M	VacJ family lipoprotein	vacJ	-	-	ko:K04754	-	-	-	-	ko00000	-	-	-	MlaA
CH2_k127_5239454_13	1122164.JHWF01000022_gene1733	1.435e-09	59.0	2BNP9@1|root,32HCB@2|Bacteria,1QBYA@1224|Proteobacteria,1T7JI@1236|Gammaproteobacteria,1JFGD@118969|Legionellales	118969|Legionellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_5239454_12	1279017.AQYJ01000026_gene22	1.855e-13	72.0	2DU2E@1|root,33NN7@2|Bacteria,1P5P1@1224|Proteobacteria,1SV3F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_5239454_3	1163617.SCD_n01707	4.56e-135	434.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,2VI8C@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
CH2_k127_5239454_4	1163617.SCD_n01708	6.545e-118	383.0	COG0637@1|root,COG0637@2|Bacteria,1PUMZ@1224|Proteobacteria,2VHJ3@28216|Betaproteobacteria	28216|Betaproteobacteria	G	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	cbbY	-	-	-	-	-	-	-	-	-	-	-	HAD_2
CH2_k127_5246882_0	580332.Slit_1216	1.034e-73	253.0	COG2020@1|root,COG2020@2|Bacteria,1PPQV@1224|Proteobacteria,2VR3S@28216|Betaproteobacteria	28216|Betaproteobacteria	O	methyltransferase activity	-	-	2.1.1.334	ko:K21310	ko00920,map00920	-	R11546	RC02653	ko00000,ko00001,ko01000	-	-	-	-
CH2_k127_5246882_2	948106.AWZT01000053_gene1589	8.739e-56	201.0	COG5654@1|root,COG5654@2|Bacteria,1N6P3@1224|Proteobacteria,2VSGY@28216|Betaproteobacteria,1KFU4@119060|Burkholderiaceae	28216|Betaproteobacteria	S	RES	-	-	-	-	-	-	-	-	-	-	-	-	RES
CH2_k127_5246882_3	232721.Ajs_0568	1.55e-54	196.0	COG5642@1|root,COG5642@2|Bacteria,1RJWF@1224|Proteobacteria,2VTQA@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF2384)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2384
CH2_k127_5246882_1	76114.p2A75	1.677e-57	201.0	COG3177@1|root,COG3177@2|Bacteria,1MXWY@1224|Proteobacteria,2VMBH@28216|Betaproteobacteria	28216|Betaproteobacteria	K	filamentation induced by cAMP protein Fic	-	-	-	-	-	-	-	-	-	-	-	-	Fic
CH2_k127_5282115_6	292415.Tbd_0749	3.61e-49	178.0	COG3864@1|root,COG3864@2|Bacteria,1MY13@1224|Proteobacteria,2VS6Y@28216|Betaproteobacteria,1KSGS@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Putative metallopeptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2201,DUF2201_N
CH2_k127_5282115_1	1123392.AQWL01000004_gene2558	1.249e-184	582.0	COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,2VRJN@28216|Betaproteobacteria,1KSUB@119069|Hydrogenophilales	119069|Hydrogenophilales	S	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
CH2_k127_5282115_3	1163617.SCD_n00965	7.342e-84	281.0	COG1051@1|root,COG1051@2|Bacteria,1REBW@1224|Proteobacteria,2VQ39@28216|Betaproteobacteria	28216|Betaproteobacteria	F	NUDIX hydrolase	nudC_1	-	-	-	-	-	-	-	-	-	-	-	NUDIX,Nudix_N_2
CH2_k127_5282115_5	1163617.SCD_n00327	1.748e-75	274.0	2AAP7@1|root,31015@2|Bacteria,1RDTH@1224|Proteobacteria,2VR2B@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_5282115_0	1163617.SCD_n00964	0.0	1063.0	COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,2VHHJ@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
CH2_k127_5282115_4	292415.Tbd_0232	2.684e-80	271.0	COG0494@1|root,COG0494@2|Bacteria,1RCX7@1224|Proteobacteria,2VRU5@28216|Betaproteobacteria,1KS1M@119069|Hydrogenophilales	119069|Hydrogenophilales	L	NUDIX domain	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
CH2_k127_5282115_2	748247.AZKH_1283	8.522e-120	385.0	COG0450@1|root,COG0450@2|Bacteria,1MWPY@1224|Proteobacteria,2VI7T@28216|Betaproteobacteria,2KUMS@206389|Rhodocyclales	206389|Rhodocyclales	O	C-terminal domain of 1-Cys peroxiredoxin	ahpC	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
CH2_k127_5282115_7	1163617.SCD_n00836	4.899e-49	176.0	COG0312@1|root,COG0312@2|Bacteria,1MUVW@1224|Proteobacteria,2VHJ4@28216|Betaproteobacteria	28216|Betaproteobacteria	S	peptidase U62, modulator of DNA gyrase	pmbA	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
CH2_k127_5299469_4	1502770.JQMG01000001_gene165	1.138e-77	260.0	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,2VH1U@28216|Betaproteobacteria,2KKX8@206350|Nitrosomonadales	206350|Nitrosomonadales	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
CH2_k127_5299469_1	1163617.SCD_n01849	1.649e-181	575.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,2VHBG@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5,6.2.1.9	ko:K01903,ko:K14067	ko00020,ko00630,ko00640,ko00660,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00630,map00640,map00660,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00346,M00374,M00620	R00405,R01256,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
CH2_k127_5299469_2	323848.Nmul_A0328	2.694e-176	580.0	COG2199@1|root,COG2200@1|root,COG3829@1|root,COG3852@1|root,COG5002@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,COG3829@2|Bacteria,COG3852@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2WHDZ@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_4,PAS_9
CH2_k127_5299469_3	1163617.SCD_n02416	3.818e-160	512.0	COG3146@1|root,COG3146@2|Bacteria,1MU35@1224|Proteobacteria,2VH0Z@28216|Betaproteobacteria	28216|Betaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09919	-	-	-	-	ko00000	-	-	-	FemAB_like
CH2_k127_5299469_5	261292.Nit79A3_2906	9.812e-46	173.0	COG1371@1|root,COG1371@2|Bacteria,1N301@1224|Proteobacteria,2VVPE@28216|Betaproteobacteria,3739H@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Archease protein family (MTH1598/TM1083)	-	-	-	-	-	-	-	-	-	-	-	-	Archease
CH2_k127_5299469_0	1123368.AUIS01000029_gene1288	1.535e-245	764.0	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,1RMXH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the RtcB family	rtcB	-	6.5.1.3	ko:K14415,ko:K18148	ko01501,map01501	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	RtcB
CH2_k127_5300127_9	1500897.JQNA01000001_gene6781	1.197e-46	169.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,2VH0J@28216|Betaproteobacteria,1K2TQ@119060|Burkholderiaceae	28216|Betaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
CH2_k127_5300127_6	1163617.SCD_n00670	6.695e-77	265.0	COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,2VJ98@28216|Betaproteobacteria	28216|Betaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
CH2_k127_5300127_5	1165096.ARWF01000001_gene1863	3.277e-77	261.0	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,2VQ3U@28216|Betaproteobacteria,2KM83@206350|Nitrosomonadales	206350|Nitrosomonadales	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
CH2_k127_5300127_2	1163617.SCD_n00668	5.816e-126	407.0	COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,2VIA5@28216|Betaproteobacteria	28216|Betaproteobacteria	K	transcriptional regulatory protein	yebC	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
CH2_k127_5300127_1	1163617.SCD_n00667	5.817e-148	478.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,2VI41@28216|Betaproteobacteria	28216|Betaproteobacteria	I	phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	clsB	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
CH2_k127_5300127_3	323848.Nmul_A0606	2.053e-120	392.0	COG3568@1|root,COG3568@2|Bacteria,1MVN7@1224|Proteobacteria,2VJYW@28216|Betaproteobacteria,372S8@32003|Nitrosomonadales	28216|Betaproteobacteria	L	PFAM Endonuclease exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CH2_k127_5300127_8	323848.Nmul_A0604	1.233e-61	215.0	COG0494@1|root,COG0494@2|Bacteria,1RH6N@1224|Proteobacteria,2VR3U@28216|Betaproteobacteria,3738S@32003|Nitrosomonadales	28216|Betaproteobacteria	L	Nudix hydrolase	ntpA	-	3.6.1.67	ko:K08310	ko00790,map00790	M00126	R04638	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NUDIX
CH2_k127_5300127_0	583345.Mmol_2121	1.821e-318	981.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,2VHKQ@28216|Betaproteobacteria,2KM0Z@206350|Nitrosomonadales	206350|Nitrosomonadales	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
CH2_k127_5300127_4	1163617.SCD_n00662	2.143e-94	313.0	COG2928@1|root,COG2928@2|Bacteria,1MWT5@1224|Proteobacteria,2VH65@28216|Betaproteobacteria	28216|Betaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
CH2_k127_5300127_11	62928.azo3237	3.09e-36	138.0	COG2331@1|root,COG2331@2|Bacteria,1N6Q9@1224|Proteobacteria,2VTX5@28216|Betaproteobacteria,2KXAG@206389|Rhodocyclales	206389|Rhodocyclales	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
CH2_k127_5300127_7	1121406.JAEX01000003_gene1697	9.877e-63	226.0	COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,42MN6@68525|delta/epsilon subdivisions,2WK6T@28221|Deltaproteobacteria,2M8ZU@213115|Desulfovibrionales	28221|Deltaproteobacteria	N	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
CH2_k127_5300127_10	1121406.JAEX01000003_gene1698	2.99e-41	163.0	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,42RH7@68525|delta/epsilon subdivisions,2WP03@28221|Deltaproteobacteria,2MA6B@213115|Desulfovibrionales	28221|Deltaproteobacteria	N	OmpA family	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
CH2_k127_5335957_5	666681.M301_2413	3.583e-06	49.0	COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria,2VIBZ@28216|Betaproteobacteria,2KMG6@206350|Nitrosomonadales	206350|Nitrosomonadales	GM	Saccharopine dehydrogenase NADP binding domain	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	Epimerase
CH2_k127_5335957_1	1163617.SCD_n00398	2.913e-184	586.0	COG0617@1|root,COG0617@2|Bacteria,1MU2X@1224|Proteobacteria,2VIN5@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases	cca	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
CH2_k127_5335957_0	1163617.SCD_n00535	3.098e-214	691.0	COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,2VI5J@28216|Betaproteobacteria	28216|Betaproteobacteria	M	AsmA family	-	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA,AsmA_2
CH2_k127_5335957_2	1205683.CAKR01000014_gene96	1.633e-34	134.0	COG4679@1|root,COG4679@2|Bacteria,1MZC9@1224|Proteobacteria,1TKU4@1236|Gammaproteobacteria,41HP5@629|Yersinia	1236|Gammaproteobacteria	S	Phage derived protein Gp49-like (DUF891)	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
CH2_k127_5335957_3	879212.DespoDRAFT_01894	2.844e-26	110.0	COG5606@1|root,COG5606@2|Bacteria,1PQ51@1224|Proteobacteria,43EK8@68525|delta/epsilon subdivisions,2X0YR@28221|Deltaproteobacteria,2MMFW@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_37
CH2_k127_5335957_4	1173027.Mic7113_4415	3.126e-25	108.0	COG4095@1|root,COG4095@2|Bacteria,1G9AI@1117|Cyanobacteria,1HCTA@1150|Oscillatoriales	1117|Cyanobacteria	S	PQ loop repeat	-	-	-	ko:K15383	-	-	-	-	ko00000,ko02000	9.A.58.2	-	-	MtN3_slv,PQ-loop
CH2_k127_5341903_0	1163617.SCD_n01485	1.184e-130	421.0	COG2890@1|root,COG2890@2|Bacteria,1MX8Q@1224|Proteobacteria,2VIPK@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue	prmB	-	2.1.1.298	ko:K07320	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03009	-	-	-	MTS
CH2_k127_5341903_2	1266925.JHVX01000009_gene62	2.725e-102	344.0	COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,2VITB@28216|Betaproteobacteria,372R2@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
CH2_k127_5341903_3	1288494.EBAPG3_1840	2.384e-75	257.0	COG1386@1|root,COG1386@2|Bacteria,1PUA6@1224|Proteobacteria,2VKIN@28216|Betaproteobacteria,372XP@32003|Nitrosomonadales	28216|Betaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
CH2_k127_5341903_1	1163617.SCD_n01480	1.725e-111	366.0	COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,2VKE7@28216|Betaproteobacteria	28216|Betaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
CH2_k127_5341903_4	314285.KT71_08350	4.78e-32	126.0	COG0466@1|root,COG0466@2|Bacteria,1NTR5@1224|Proteobacteria,1RPID@1236|Gammaproteobacteria,1J5G2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon2	-	3.4.21.53	ko:K01338,ko:K08675	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03029	-	-	-	AAA,LON_substr_bdg,Lon_C
CH2_k127_5408803_1	1163617.SCD_n02785	2.049e-136	436.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,2VISB@28216|Betaproteobacteria	28216|Betaproteobacteria	I	acetyl-CoA carboxylase biotin carboxylase	accC	GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
CH2_k127_5408803_4	1123392.AQWL01000002_gene1936	2.283e-55	201.0	COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,2VR5S@28216|Betaproteobacteria,1KS8I@119069|Hydrogenophilales	119069|Hydrogenophilales	I	Biotin-requiring enzyme	-	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
CH2_k127_5408803_2	1163617.SCD_n02787	5.951e-62	216.0	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,2VR4Y@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
CH2_k127_5408803_3	1163617.SCD_n02788	2.904e-61	215.0	COG0526@1|root,COG0526@2|Bacteria,1MZ5J@1224|Proteobacteria,2VU93@28216|Betaproteobacteria	28216|Betaproteobacteria	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	tlpA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
CH2_k127_5408803_0	1123393.KB891316_gene1919	1.423e-257	816.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,2VI8I@28216|Betaproteobacteria,1KS2S@119069|Hydrogenophilales	119069|Hydrogenophilales	CO	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps	-	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
CH2_k127_5408803_5	1163617.SCD_n02790	8.633e-44	161.0	COG1324@1|root,COG1324@2|Bacteria,1N6TN@1224|Proteobacteria,2VUC8@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Divalent ion tolerance protein	cutA	GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
CH2_k127_5408803_6	292415.Tbd_2561	7.932e-26	111.0	COG3030@1|root,COG3030@2|Bacteria,1NHHU@1224|Proteobacteria,2VX8I@28216|Betaproteobacteria	28216|Betaproteobacteria	S	FxsA cytoplasmic membrane protein	-	-	-	ko:K07113	-	-	-	-	ko00000	-	-	-	FxsA
CH2_k127_5470073_1	1163617.SCD_n00834	2.614e-88	293.0	COG0521@1|root,COG0521@2|Bacteria,1R9W2@1224|Proteobacteria,2VH28@28216|Betaproteobacteria	28216|Betaproteobacteria	H	molybdenum cofactor	mogA	-	2.7.7.75	ko:K03831	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
CH2_k127_5470073_0	1123393.KB891328_gene593	7.564e-123	414.0	2DBUQ@1|root,2ZB76@2|Bacteria,1R4DM@1224|Proteobacteria,2VS5V@28216|Betaproteobacteria,1KSNQ@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_5470073_2	1121035.AUCH01000005_gene145	8.477e-56	216.0	2DBUQ@1|root,2ZB76@2|Bacteria,1R4DM@1224|Proteobacteria,2VP87@28216|Betaproteobacteria,2KVUH@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_5476905_5	261292.Nit79A3_1506	2.433e-21	93.0	COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,2VHVU@28216|Betaproteobacteria,371X3@32003|Nitrosomonadales	28216|Betaproteobacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	-	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
CH2_k127_5476905_1	1123393.KB891316_gene1246	3.024e-172	546.0	COG0820@1|root,COG0820@2|Bacteria,1Q0HH@1224|Proteobacteria,2VMGJ@28216|Betaproteobacteria,1KRX5@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Radical SAM superfamily	-	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
CH2_k127_5476905_2	1163617.SCD_n00995	1.659e-105	345.0	COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,2VK3W@28216|Betaproteobacteria	28216|Betaproteobacteria	L	DNA polymerase III, epsilon subunit	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
CH2_k127_5476905_3	697282.Mettu_3162	2.027e-73	258.0	COG0642@1|root,COG2199@1|root,COG2202@1|root,COG3829@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,COG3829@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,Hpt,NMT1,PAS,PAS_3,PAS_4,PAS_9,Response_reg
CH2_k127_5476905_4	323848.Nmul_A1137	1.971e-37	144.0	COG1950@1|root,COG1950@2|Bacteria,1N1DF@1224|Proteobacteria,2VUY1@28216|Betaproteobacteria,373DY@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Mycobacterial 4 TMS phage holin, superfamily IV	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
CH2_k127_5476905_0	1163617.SCD_n02260	4.352e-198	621.0	COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,2VIJH@28216|Betaproteobacteria	28216|Betaproteobacteria	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components	nasF	-	-	ko:K02051,ko:K15576,ko:K22067	ko00910,ko02010,map00910,map02010	M00188,M00438	-	-	ko00000,ko00001,ko00002,ko02000,ko02022	3.A.1.16,3.A.1.16.1,3.A.1.16.2,3.A.1.17	-	-	NMT1_2
CH2_k127_5578005_4	1123393.KB891317_gene2450	2.963e-77	261.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,2VIHG@28216|Betaproteobacteria,1KSCK@119069|Hydrogenophilales	119069|Hydrogenophilales	EH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
CH2_k127_5578005_1	1163617.SCD_n01028	6.909e-179	565.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1MU60@1224|Proteobacteria,2VJEV@28216|Betaproteobacteria	28216|Betaproteobacteria	E	chorismate mutase	pheA	-	4.2.1.51,4.2.1.91,5.4.99.5	ko:K01713,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
CH2_k127_5578005_2	1163617.SCD_n01029	1.289e-172	547.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,2VIPQ@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC2	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CH2_k127_5578005_0	1163617.SCD_n01030	3.343e-185	582.0	COG2876@1|root,COG2876@2|Bacteria,1QVAD@1224|Proteobacteria,2VH85@28216|Betaproteobacteria	28216|Betaproteobacteria	E	phospho-2-dehydro-3-deoxyheptonate aldolase	aroF	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
CH2_k127_5578005_3	1163617.SCD_n01031	3.95e-113	371.0	COG0287@1|root,COG0287@2|Bacteria,1QTZA@1224|Proteobacteria,2VIS1@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
CH2_k127_5578005_5	1123487.KB892838_gene3821	3.93e-71	243.0	COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,2VGZF@28216|Betaproteobacteria,2KUWK@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	cmk	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin,EPSP_synthase
CH2_k127_5580018_2	396588.Tgr7_0830	7.599e-13	68.0	COG1469@1|root,COG1469@2|Bacteria,1MV1B@1224|Proteobacteria,1RNDY@1236|Gammaproteobacteria,1WW3H@135613|Chromatiales	135613|Chromatiales	S	Converts GTP to 7,8-dihydroneopterin triphosphate	folE2	-	3.5.4.16	ko:K09007	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GCHY-1
CH2_k127_5580018_1	748247.AZKH_0398	6.634e-36	145.0	COG5581@1|root,COG5581@2|Bacteria,1RJ1B@1224|Proteobacteria,2VTGM@28216|Betaproteobacteria,2KWP1@206389|Rhodocyclales	206389|Rhodocyclales	M	Flagellar protein YcgR	-	-	-	-	-	-	-	-	-	-	-	-	PilZ,YcgR_2
CH2_k127_5580018_0	1026882.MAMP_02979	1.704e-48	179.0	COG3577@1|root,COG3577@2|Bacteria,1N2PE@1224|Proteobacteria,1S66F@1236|Gammaproteobacteria,462KA@72273|Thiotrichales	72273|Thiotrichales	S	Clan AA aspartic protease	-	-	-	ko:K06985	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	gag-asp_proteas
CH2_k127_5595076_1	1163617.SCD_n01755	2.924e-119	387.0	COG0726@1|root,COG0726@2|Bacteria,1N8Q4@1224|Proteobacteria,2VKEP@28216|Betaproteobacteria	28216|Betaproteobacteria	G	polysaccharide deacetylase	arnD	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
CH2_k127_5595076_3	583345.Mmol_2041	1.364e-63	221.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,2VR4P@28216|Betaproteobacteria,2KMRJ@206350|Nitrosomonadales	206350|Nitrosomonadales	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
CH2_k127_5595076_0	1288494.EBAPG3_25730	2.529e-236	737.0	COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,2VH4P@28216|Betaproteobacteria,372PF@32003|Nitrosomonadales	28216|Betaproteobacteria	T	Large family of predicted nucleotide-binding domains	phoH	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
CH2_k127_5595076_5	584708.Apau_2185	2.287e-41	157.0	COG2445@1|root,COG2445@2|Bacteria,3TBPJ@508458|Synergistetes	508458|Synergistetes	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
CH2_k127_5595076_4	1283300.ATXB01000001_gene977	1.102e-51	189.0	COG1669@1|root,COG1669@2|Bacteria,1RH50@1224|Proteobacteria,1SBXX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	DNA polymerase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
CH2_k127_5595076_2	1163617.SCD_n00462	7.613e-118	386.0	COG2175@1|root,COG2175@2|Bacteria,1R5KS@1224|Proteobacteria,2VIG6@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Taurine catabolism dioxygenase TauD, TfdA family	-	-	-	-	-	-	-	-	-	-	-	-	TauD
CH2_k127_5595076_6	1163617.SCD_n02723	1.421e-35	144.0	28IET@1|root,2Z8GT@2|Bacteria,1R4FQ@1224|Proteobacteria,2VUGA@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_5595076_7	292415.Tbd_2489	1.137e-34	134.0	COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,2VHAX@28216|Betaproteobacteria,1KSA5@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Rhodanese Homology Domain	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
CH2_k127_5615958_2	396588.Tgr7_3019	1.044e-82	276.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,1RMY7@1236|Gammaproteobacteria,1WXP7@135613|Chromatiales	135613|Chromatiales	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
CH2_k127_5615958_1	1163617.SCD_n03009	1.189e-176	556.0	COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,2VHC2@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
CH2_k127_5615958_3	1229485.AMYV01000063_gene3266	1.505e-12	67.0	COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,1RMDH@1236|Gammaproteobacteria,1J4IA@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006725,GO:0006778,GO:0006779,GO:0006780,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019353,GO:0019438,GO:0019752,GO:0033013,GO:0033014,GO:0033526,GO:0034641,GO:0042168,GO:0042440,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046394,GO:0046483,GO:0046501,GO:0046502,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	iPC815.YPO3734,iSBO_1134.SBO_4018	URO-D
CH2_k127_5615958_0	323848.Nmul_A2327	3.704e-261	823.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,2VINT@28216|Betaproteobacteria,372GD@32003|Nitrosomonadales	28216|Betaproteobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
CH2_k127_5617082_3	228410.NE0847	1.088e-110	369.0	COG0726@1|root,COG0726@2|Bacteria,1MVKH@1224|Proteobacteria,2VIWN@28216|Betaproteobacteria,372SU@32003|Nitrosomonadales	28216|Betaproteobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
CH2_k127_5617082_7	1131553.JIBI01000008_gene1279	1.582e-75	263.0	COG2227@1|root,COG2227@2|Bacteria,1QVIA@1224|Proteobacteria,2VWHZ@28216|Betaproteobacteria	28216|Betaproteobacteria	H	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CH2_k127_5617082_1	292415.Tbd_0297	6.016e-139	454.0	COG3307@1|root,COG3307@2|Bacteria,1PX0E@1224|Proteobacteria,2VKT7@28216|Betaproteobacteria,1KSY0@119069|Hydrogenophilales	119069|Hydrogenophilales	M	O-antigen ligase like membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
CH2_k127_5617082_6	1232410.KI421421_gene3374	2.186e-79	280.0	2AK27@1|root,31ARV@2|Bacteria,1REZR@1224|Proteobacteria,42W34@68525|delta/epsilon subdivisions,2WRFM@28221|Deltaproteobacteria,43VW3@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_5617082_5	1173026.Glo7428_1321	1.902e-94	324.0	COG2327@1|root,COG2327@2|Bacteria,1GBF9@1117|Cyanobacteria	1117|Cyanobacteria	S	Polysaccharide pyruvyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_5617082_4	102129.Lepto7375DRAFT_7592	6.487e-109	367.0	COG0438@1|root,COG0438@2|Bacteria,1GA3S@1117|Cyanobacteria,1HH3K@1150|Oscillatoriales	1117|Cyanobacteria	M	Glycosyl transferases group 1	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_trans_1_4,Glycos_transf_2
CH2_k127_5617082_2	1288494.EBAPG3_29240	1.125e-123	413.0	COG2244@1|root,COG2244@2|Bacteria,1R9I0@1224|Proteobacteria,2VQSW@28216|Betaproteobacteria,374P1@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Polysaccharide biosynthesis protein	-	-	-	ko:K03328	-	-	-	-	ko00000	2.A.66.2	-	-	Polysacc_synt_3,Polysacc_synt_C
CH2_k127_5617082_0	1123368.AUIS01000019_gene1212	2.259e-155	497.0	COG1902@1|root,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,1RMII@1236|Gammaproteobacteria,2NC3Y@225057|Acidithiobacillales	225057|Acidithiobacillales	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
CH2_k127_5617082_8	1163617.SCD_n02354	5.554e-37	139.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2VVTG@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Cold shock protein	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
CH2_k127_5617082_9	580332.Slit_0121	2.268e-31	123.0	COG1432@1|root,COG1432@2|Bacteria,1MX5C@1224|Proteobacteria,2VK44@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
CH2_k127_5624911_5	1163617.SCD_n00850	2.962e-29	120.0	2EBKH@1|root,335KX@2|Bacteria,1NAWH@1224|Proteobacteria,2W4UC@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_5624911_4	1101195.Meth11DRAFT_2163	4.011e-42	160.0	COG2137@1|root,COG2137@2|Bacteria,1N6P6@1224|Proteobacteria,2VTYZ@28216|Betaproteobacteria,2KMR6@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
CH2_k127_5624911_0	1163617.SCD_n00848	2.394e-198	621.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,2VHNA@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
CH2_k127_5624911_2	1163617.SCD_n00847	2.197e-60	220.0	COG1546@1|root,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,2VSQF@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA
CH2_k127_5624911_3	1163617.SCD_n00846	1.263e-56	201.0	COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,2VSP2@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)	pgpA	-	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	-	PgpA
CH2_k127_5624911_1	1163617.SCD_n00845	9.554e-91	301.0	COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,2VI0Q@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
CH2_k127_5668281_0	1304883.KI912532_gene2349	5.513e-228	712.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,2VHCZ@28216|Betaproteobacteria,2KUGU@206389|Rhodocyclales	206389|Rhodocyclales	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	cusA	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
CH2_k127_5668281_6	1163617.SCD_n01858	9.945e-54	192.0	COG3439@1|root,COG3439@2|Bacteria,1RH9Z@1224|Proteobacteria,2VTC8@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
CH2_k127_5668281_7	159087.Daro_2266	7.383e-05	51.0	2D91J@1|root,32TSD@2|Bacteria,1N65Q@1224|Proteobacteria,2VUNJ@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_5668281_4	1266925.JHVX01000011_gene1486	2.842e-109	357.0	COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,2VIUV@28216|Betaproteobacteria,371NN@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
CH2_k127_5668281_5	1349767.GJA_1165	1.111e-96	332.0	COG2935@1|root,COG2935@2|Bacteria,1MW62@1224|Proteobacteria,2VJ8E@28216|Betaproteobacteria,473K0@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate	ate	-	2.3.2.29	ko:K21420	-	-	R11547,R11548	RC00064	ko00000,ko01000	-	-	-	ATE_C,ATE_N
CH2_k127_5668281_2	1123020.AUIE01000003_gene455	3.846e-129	425.0	COG2206@1|root,COG2206@2|Bacteria,1N5T4@1224|Proteobacteria,1RZIM@1236|Gammaproteobacteria,1YHHS@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	T	Domain of unknown function (DUF3391)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3391,HD,HD_5
CH2_k127_5668281_1	1123487.KB892857_gene2452	3.485e-134	457.0	COG0642@1|root,COG0642@2|Bacteria,1NXDJ@1224|Proteobacteria,2W1GY@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	rpfC	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,CHASE,HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_7,PAS_9,Response_reg
CH2_k127_5668281_3	1163617.SCD_n01864	2.413e-123	395.0	COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,2VIIR@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
CH2_k127_5681598_4	1452718.JBOY01000136_gene1453	2.089e-23	102.0	COG3666@1|root,COG3666@2|Bacteria,1N3QR@1224|Proteobacteria,1RR2W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG3666 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
CH2_k127_5681598_5	391598.FBBAL38_06870	1.974e-17	86.0	28MKG@1|root,2ZAWQ@2|Bacteria,4NIYN@976|Bacteroidetes,1HZ4C@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_5681598_1	1163617.SCD_n00691	3.09e-67	234.0	COG0746@1|root,COG0746@2|Bacteria,1RH3M@1224|Proteobacteria,2VQR2@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
CH2_k127_5681598_2	1163617.SCD_n00730	3.8e-32	129.0	2E445@1|root,32Z0E@2|Bacteria,1N7FY@1224|Proteobacteria,2VWT7@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_5681598_0	1163617.SCD_n00731	2.822e-120	394.0	COG0457@1|root,COG0457@2|Bacteria,1QV5B@1224|Proteobacteria,2WGRP@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2,TPR_16
CH2_k127_5681598_3	635013.TherJR_0744	8.758e-29	118.0	COG3383@1|root,COG3383@2|Bacteria,1TT6D@1239|Firmicutes,24YN9@186801|Clostridia,267CA@186807|Peptococcaceae	186801|Clostridia	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	fdhA	-	1.17.1.10,1.17.1.9	ko:K00123,ko:K05299	ko00630,ko00680,ko00720,ko01100,ko01120,ko01200,map00630,map00680,map00720,map01100,map01120,map01200	M00377	R00134,R00519	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
CH2_k127_5697003_2	1123368.AUIS01000019_gene1207	4.769e-80	269.0	COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,1RQQ3@1236|Gammaproteobacteria,2NCT4@225057|Acidithiobacillales	225057|Acidithiobacillales	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
CH2_k127_5697003_1	395494.Galf_0851	2.51e-131	436.0	COG0642@1|root,COG2205@2|Bacteria,1N1Z2@1224|Proteobacteria,2VJBG@28216|Betaproteobacteria,44W7J@713636|Nitrosomonadales	28216|Betaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	qseC	-	2.7.13.3	ko:K07645	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	2CSK_N,HATPase_c,HisKA
CH2_k127_5697003_0	1123393.KB891331_gene2919	1.296e-305	964.0	COG3829@1|root,COG5001@1|root,COG5002@1|root,COG3829@2|Bacteria,COG5001@2|Bacteria,COG5002@2|Bacteria,1MU2C@1224|Proteobacteria,2VJMN@28216|Betaproteobacteria,1KS9E@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,PAS_4
CH2_k127_5697003_3	159087.Daro_0059	1.36e-45	176.0	COG3221@1|root,COG3221@2|Bacteria,1N5FI@1224|Proteobacteria,2VTXP@28216|Betaproteobacteria,2KWYV@206389|Rhodocyclales	206389|Rhodocyclales	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
CH2_k127_5697003_4	1163617.SCD_n02840	3.172e-06	49.0	COG0548@1|root,COG1246@1|root,COG0548@2|Bacteria,COG1246@2|Bacteria,1MUUP@1224|Proteobacteria,2VGZC@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Belongs to the acetyltransferase family. ArgA subfamily	argA	-	2.3.1.1	ko:K14682	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,Acetyltransf_1
CH2_k127_5775706_2	1163617.SCD_n01042	9.63e-25	106.0	COG1555@1|root,COG1555@2|Bacteria,1N6Q3@1224|Proteobacteria	1224|Proteobacteria	L	Competence protein ComEA	comEA	GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3
CH2_k127_5775706_0	1379281.AVAG01000048_gene864	8.913e-150	488.0	COG0662@1|root,COG0836@1|root,COG0662@2|Bacteria,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,42MDP@68525|delta/epsilon subdivisions,2WJEN@28221|Deltaproteobacteria,2M8IG@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	TIGRFAM Mannose-1-phosphate guanylyltransferase mannose-6-phosphate isomerase	-	-	2.7.7.13,5.3.1.8	ko:K00971,ko:K16011	ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025	M00114,M00361,M00362	R00885,R01819	RC00002,RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
CH2_k127_5775706_1	1163617.SCD_n01043	1.397e-83	287.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_4,dCache_1
CH2_k127_5779203_0	1163617.SCD_n02838	0.0	1037.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,2VHH8@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
CH2_k127_5784296_7	1163617.SCD_n02621	2.021e-68	234.0	COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,2VHU0@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
CH2_k127_5784296_4	1163617.SCD_n02623	1.951e-126	411.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,2VHK3@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
CH2_k127_5784296_9	1163617.SCD_n02624	1.88e-40	157.0	COG3017@1|root,COG3017@2|Bacteria,1N02T@1224|Proteobacteria,2VUIR@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein	lolB	-	-	ko:K02494	-	-	-	-	ko00000	-	-	-	LolB
CH2_k127_5784296_1	1163617.SCD_n02625	1.043e-195	626.0	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,2VI6C@28216|Betaproteobacteria	28216|Betaproteobacteria	H	SMART Tetratricopeptide domain protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_8
CH2_k127_5784296_5	265072.Mfla_0682	1.587e-124	406.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,2VJ2B@28216|Betaproteobacteria,2KM5I@206350|Nitrosomonadales	206350|Nitrosomonadales	V	PFAM ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
CH2_k127_5784296_0	522306.CAP2UW1_1338	8.656e-204	640.0	COG1373@1|root,COG1373@2|Bacteria,1MWBT@1224|Proteobacteria,2VK9X@28216|Betaproteobacteria,1KQXT@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	AAA domain	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
CH2_k127_5784296_6	1163617.SCD_n02627	8.346e-92	308.0	COG1277@1|root,COG1277@2|Bacteria,1NZZ9@1224|Proteobacteria,2VRRA@28216|Betaproteobacteria	28216|Betaproteobacteria	N	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
CH2_k127_5784296_2	1163617.SCD_n02628	1.426e-182	581.0	COG3225@1|root,COG3225@2|Bacteria,1MUXW@1224|Proteobacteria,2VMDE@28216|Betaproteobacteria	28216|Betaproteobacteria	N	transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
CH2_k127_5784296_8	1163617.SCD_n02629	6.508e-62	223.0	2E2GR@1|root,32XKS@2|Bacteria,1N41X@1224|Proteobacteria,2VUN3@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
CH2_k127_5784296_3	637389.Acaty_c0158	2.01e-173	551.0	COG3177@1|root,COG3177@2|Bacteria,1MV69@1224|Proteobacteria,1RM9J@1236|Gammaproteobacteria,2NE4Z@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Domain of unknown function (DUF4172)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4172,Fic
CH2_k127_5784296_10	1163617.SCD_n00544	2.331e-17	81.0	2EC4Z@1|root,3363S@2|Bacteria,1N9YG@1224|Proteobacteria,2W41I@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_5894102_4	1163617.SCD_n02538	1.063e-39	156.0	COG0810@1|root,COG0810@2|Bacteria,1NATT@1224|Proteobacteria,2VWBE@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
CH2_k127_5894102_2	1163617.SCD_n00218	3.688e-83	285.0	COG0676@1|root,COG0676@2|Bacteria,1Q7VN@1224|Proteobacteria,2VKZK@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Belongs to the glucose-6-phosphate 1-epimerase family	-	-	5.1.3.15	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	-	R02739	RC00563	ko00000,ko00001,ko01000	-	-	-	Aldose_epim
CH2_k127_5894102_3	580332.Slit_2208	1.323e-82	278.0	COG2230@1|root,COG2230@2|Bacteria,1QXKQ@1224|Proteobacteria,2WHPJ@28216|Betaproteobacteria,44VP5@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CH2_k127_5894102_1	1163617.SCD_n02554	7.321e-85	287.0	COG1651@1|root,COG1651@2|Bacteria,1RD39@1224|Proteobacteria,2VIHV@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process	-	-	5.3.4.1	ko:K03981	-	-	-	-	ko00000,ko01000,ko02044,ko03110	3.A.7.11.1	-	-	DsbC_N,Thioredoxin_2
CH2_k127_5894102_0	1266925.JHVX01000005_gene1826	1.793e-145	472.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,2VIPS@28216|Betaproteobacteria,372D2@32003|Nitrosomonadales	28216|Betaproteobacteria	C	TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6	ubiF	-	-	ko:K03185	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04989,R08773	RC02670	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,FAD_binding_3,SE
CH2_k127_5894102_5	93220.LV28_10970	8.03e-07	51.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,2VKV7@28216|Betaproteobacteria,1JZQC@119060|Burkholderiaceae	28216|Betaproteobacteria	CH	Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family	ubiH	-	-	ko:K03185	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04989,R08773	RC02670	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
CH2_k127_6099341_2	1288494.EBAPG3_25740	2.482e-234	731.0	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,2VIKN@28216|Betaproteobacteria,372T4@32003|Nitrosomonadales	28216|Betaproteobacteria	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
CH2_k127_6099341_18	1266925.JHVX01000009_gene133	4.026e-63	220.0	COG0359@1|root,COG0359@2|Bacteria,1RD0R@1224|Proteobacteria,2VR40@28216|Betaproteobacteria,37399@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
CH2_k127_6099341_23	323848.Nmul_A1949	3.538e-37	141.0	COG0238@1|root,COG0238@2|Bacteria,1MZ8U@1224|Proteobacteria,2VTWT@28216|Betaproteobacteria,373BA@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
CH2_k127_6099341_25	1163617.SCD_n01791	1.33e-23	102.0	COG2965@1|root,COG2965@2|Bacteria,1N98W@1224|Proteobacteria,2VVZ4@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Binds single-stranded DNA at the primosome assembly site (PAS)	priB	-	-	ko:K02686	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SSB
CH2_k127_6099341_19	1132855.KB913035_gene1410	7.037e-61	212.0	COG0360@1|root,COG0360@2|Bacteria,1RH82@1224|Proteobacteria,2VR79@28216|Betaproteobacteria,2KMRN@206350|Nitrosomonadales	206350|Nitrosomonadales	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
CH2_k127_6099341_6	1163617.SCD_n00932	8.437e-171	542.0	COG0226@1|root,COG0226@2|Bacteria,1MUAZ@1224|Proteobacteria,2VIJV@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
CH2_k127_6099341_9	1485544.JQKP01000004_gene502	1.341e-145	467.0	COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,2VH4G@28216|Betaproteobacteria,44VHI@713636|Nitrosomonadales	28216|Betaproteobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
CH2_k127_6099341_10	1163617.SCD_n00928	5.637e-145	463.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,2VH6Y@28216|Betaproteobacteria	28216|Betaproteobacteria	P	phosphate transport system permease	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
CH2_k127_6099341_8	1163617.SCD_n00927	8.403e-147	467.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,2VI4J@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
CH2_k127_6099341_3	1163617.SCD_n00926	7.128e-224	702.0	COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,2VI3U@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
CH2_k127_6099341_14	580332.Slit_1062	3.484e-105	348.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,2VH2Q@28216|Betaproteobacteria,44V46@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
CH2_k127_6099341_1	1163617.SCD_n00924	0.0	1124.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,2VHEV@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
CH2_k127_6099341_15	1485544.JQKP01000008_gene1768	1.605e-84	284.0	COG0293@1|root,COG0293@2|Bacteria,1MW1C@1224|Proteobacteria,2VIU9@28216|Betaproteobacteria,44UZM@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit	ftsJ	-	2.1.1.166	ko:K02427	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ
CH2_k127_6099341_24	1163617.SCD_n00922	1.86e-34	134.0	COG1534@1|root,COG1534@2|Bacteria,1N8K5@1224|Proteobacteria,2VVP0@28216|Betaproteobacteria	28216|Betaproteobacteria	J	rna-binding protein	yhbY	-	-	ko:K07574	-	-	-	-	ko00000,ko03009	-	-	-	CRS1_YhbY
CH2_k127_6099341_20	1163617.SCD_n00921	4.657e-55	196.0	2AJXH@1|root,31AKJ@2|Bacteria,1RJPF@1224|Proteobacteria,2VTF5@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF4149)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4149
CH2_k127_6099341_16	1304883.KI912532_gene30	7.292e-79	265.0	COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,2VQ16@28216|Betaproteobacteria,2KUSV@206389|Rhodocyclales	206389|Rhodocyclales	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
CH2_k127_6099341_0	1163617.SCD_n00919	0.0	1858.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,2VI4A@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
CH2_k127_6099341_5	1122236.KB905142_gene492	4.521e-192	606.0	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,2VH9Q@28216|Betaproteobacteria,2KMEN@206350|Nitrosomonadales	206350|Nitrosomonadales	EF	TIGRFAM carbamoyl-phosphate synthase, small subunit	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
CH2_k127_6099341_13	1163617.SCD_n00917	4.542e-129	416.0	COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,2VJC3@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
CH2_k127_6099341_22	1163617.SCD_n00916	1.856e-37	147.0	COG2913@1|root,COG2913@2|Bacteria,1N6YW@1224|Proteobacteria,2VRC6@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamE	-	-	ko:K06186	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	SmpA_OmlA
CH2_k127_6099341_17	1123393.KB891327_gene357	1.152e-68	235.0	COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,2VR52@28216|Betaproteobacteria,1KRQ6@119069|Hydrogenophilales	119069|Hydrogenophilales	K	Ferric uptake regulator family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
CH2_k127_6099341_12	1163617.SCD_n00852	3.358e-129	424.0	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,2VKZY@28216|Betaproteobacteria	28216|Betaproteobacteria	T	PFAM EAL domain protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
CH2_k127_6099341_4	1163617.SCD_n00912	3.963e-205	653.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,2VHHA@28216|Betaproteobacteria	28216|Betaproteobacteria	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
CH2_k127_6099341_11	1163617.SCD_n00909	2.821e-132	428.0	COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,2VIV0@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
CH2_k127_6099341_7	1163617.SCD_n00908	5.443e-152	489.0	COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,2VHCK@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
CH2_k127_6099341_21	1131553.JIBI01000008_gene1315	3.644e-39	147.0	COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,2VH7Z@28216|Betaproteobacteria,3724F@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
CH2_k127_6128585_2	1163617.SCD_n02363	3.828e-164	520.0	COG4286@1|root,COG4286@2|Bacteria,1MVTY@1224|Proteobacteria,2W2U2@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Uncharacterised protein family (UPF0160)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0160
CH2_k127_6128585_14	582744.Msip34_0286	4.679e-39	153.0	COG2969@1|root,COG2969@2|Bacteria,1MZ2Q@1224|Proteobacteria,2VSGG@28216|Betaproteobacteria,2KMYV@206350|Nitrosomonadales	206350|Nitrosomonadales	S	PFAM Stringent starvation protein B	-	-	-	ko:K03600	-	-	-	-	ko00000,ko03021	-	-	-	SspB
CH2_k127_6128585_3	1163617.SCD_n00604	6.666e-112	363.0	COG0625@1|root,COG0625@2|Bacteria,1MXJD@1224|Proteobacteria,2VIAW@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Glutathione S-transferase	sspA	-	-	ko:K03599	-	-	-	-	ko00000,ko02000,ko03021	1.A.12.3.1	-	-	GST_C,GST_C_2,GST_N,GST_N_3
CH2_k127_6128585_4	292415.Tbd_1831	1.118e-104	344.0	COG2857@1|root,COG2857@2|Bacteria,1QFU2@1224|Proteobacteria,2VIR6@28216|Betaproteobacteria,1KRJ9@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Cytochrome C1 family	-	-	-	ko:K00413	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C1
CH2_k127_6128585_0	292415.Tbd_1832	5.095e-237	736.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,2VHP5@28216|Betaproteobacteria,1KRDP@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	-	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
CH2_k127_6128585_7	1163617.SCD_n00601	1.41e-100	331.0	COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,2VK46@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petA	-	1.10.2.2	ko:K00411	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,UCR_Fe-S_N
CH2_k127_6128585_10	269799.Gmet_2522	6.71e-57	201.0	COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,42RNC@68525|delta/epsilon subdivisions,2WP7G@28221|Deltaproteobacteria,43V0M@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
CH2_k127_6128585_5	1163617.SCD_n00600	5.154e-104	343.0	COG0327@1|root,COG0327@2|Bacteria,1MVUN@1224|Proteobacteria,2VIX1@28216|Betaproteobacteria	28216|Betaproteobacteria	S	dinuclear metal center protein, YbgI	ybgI	-	-	-	-	-	-	-	-	-	-	-	NIF3
CH2_k127_6128585_1	1163617.SCD_n00599	3.303e-173	550.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VJ9G@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Belongs to the peptidase S1C family	degQ	-	-	ko:K04691,ko:K04772	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
CH2_k127_6128585_8	748247.AZKH_3032	1.6e-65	240.0	COG2206@1|root,COG2206@2|Bacteria,1MWDU@1224|Proteobacteria,2VIAF@28216|Betaproteobacteria,2KZ48@206389|Rhodocyclales	206389|Rhodocyclales	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
CH2_k127_6128585_6	1123367.C666_07295	7.111e-102	339.0	COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,2VI2H@28216|Betaproteobacteria,2KUWA@206389|Rhodocyclales	206389|Rhodocyclales	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
CH2_k127_6128585_16	1000565.METUNv1_02441	1.18e-23	105.0	COG1826@1|root,COG1826@2|Bacteria,1N73F@1224|Proteobacteria,2VVPX@28216|Betaproteobacteria,2KWT9@206389|Rhodocyclales	206389|Rhodocyclales	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation	tatB	-	-	ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
CH2_k127_6128585_15	1163617.SCD_n00595	1.563e-26	109.0	COG1826@1|root,COG1826@2|Bacteria,1N6S4@1224|Proteobacteria,2VVT6@28216|Betaproteobacteria	28216|Betaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
CH2_k127_6128585_11	1163617.SCD_n00594	3.916e-50	180.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,2VSMS@28216|Betaproteobacteria	28216|Betaproteobacteria	FG	Histidine triad (Hit) protein	hitA	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	DcpS_C,HIT
CH2_k127_6128585_13	1163617.SCD_n00593	3.939e-46	169.0	COG0140@1|root,COG0140@2|Bacteria,1MZEE@1224|Proteobacteria,2VUN8@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Phosphoribosyl-ATP	hisE	-	3.6.1.31	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-PH
CH2_k127_6128585_9	580332.Slit_0629	1.717e-64	224.0	COG0139@1|root,COG0139@2|Bacteria,1MW67@1224|Proteobacteria,2VR9B@28216|Betaproteobacteria,44VV6@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH
CH2_k127_6128585_12	323848.Nmul_A0814	1.277e-47	171.0	COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,2VHY0@28216|Betaproteobacteria,3724H@32003|Nitrosomonadales	28216|Betaproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
CH2_k127_6130315_11	1235457.C404_21250	2.762e-10	61.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,2VNAX@28216|Betaproteobacteria,1K0T7@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Acyl-transferase	nlaB	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
CH2_k127_6130315_10	1163617.SCD_n02565	1.613e-62	222.0	COG1451@1|root,COG1451@2|Bacteria,1MXZU@1224|Proteobacteria,2VNC5@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Metal-dependent hydrolase	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
CH2_k127_6130315_9	1123261.AXDW01000007_gene2388	1.043e-67	231.0	COG0346@1|root,COG0346@2|Bacteria,1RCYX@1224|Proteobacteria,1S1Z9@1236|Gammaproteobacteria,1X67E@135614|Xanthomonadales	135614|Xanthomonadales	E	Glyoxalase	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
CH2_k127_6130315_6	1123368.AUIS01000035_gene73	9.169e-113	376.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NT	chemotaxis, protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CHASE3,Cache_3-Cache_2,HAMP,MCPsignal
CH2_k127_6130315_0	1163617.SCD_n02029	0.0	1064.0	COG2202@1|root,COG2203@1|root,COG5001@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2W14J@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4
CH2_k127_6130315_7	292415.Tbd_2340	6.101e-103	340.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,2VH15@28216|Betaproteobacteria,1KSRA@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Ribosomal RNA adenine dimethylases	-	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
CH2_k127_6130315_5	1163617.SCD_n02561	8.359e-138	446.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,2VJN0@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)	pdxA	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
CH2_k127_6130315_2	1163617.SCD_n02560	5.052e-170	545.0	COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,2VHHS@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3,SurA_N
CH2_k127_6130315_1	1163617.SCD_n02559	9.882e-227	724.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,2VIJ7@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA,OstA_C
CH2_k127_6130315_3	292415.Tbd_2336	1.451e-155	497.0	COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,2VHBC@28216|Betaproteobacteria,1KRX6@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Phosphotransferase enzyme family	-	-	2.7.1.221	ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH
CH2_k127_6130315_8	1101195.Meth11DRAFT_0657	3.359e-89	301.0	COG1208@1|root,COG1208@2|Bacteria,1R9ZD@1224|Proteobacteria,2VJUN@28216|Betaproteobacteria,2KMGT@206350|Nitrosomonadales	206350|Nitrosomonadales	JM	PFAM Nucleotidyl transferase	-	-	2.7.7.99	ko:K00992	ko00520,ko01100,map00520,map01100	-	R11025	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
CH2_k127_6130315_4	1163617.SCD_n02556	1.648e-148	475.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,2VHQI@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Belongs to the peptidase M24B family	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
CH2_k127_6163907_1	265072.Mfla_0079	7.147e-140	454.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,2VI1J@28216|Betaproteobacteria,2KKSQ@206350|Nitrosomonadales	206350|Nitrosomonadales	NU	PFAM type II secretion system	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
CH2_k127_6163907_0	1101195.Meth11DRAFT_0142	5.461e-282	877.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria,2KKZR@206350|Nitrosomonadales	206350|Nitrosomonadales	NU	General secretory system II protein E domain protein	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
CH2_k127_6163907_3	1123392.AQWL01000004_gene2751	2.862e-51	199.0	COG0457@1|root,COG0457@2|Bacteria,1RKBG@1224|Proteobacteria,2VQFW@28216|Betaproteobacteria,1KRYK@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_6163907_2	1123393.KB891328_gene590	3.841e-139	455.0	COG1450@1|root,COG1450@2|Bacteria,1MVNC@1224|Proteobacteria,2VMT1@28216|Betaproteobacteria,1KSY9@119069|Hydrogenophilales	119069|Hydrogenophilales	NU	Secretin and TonB N terminus short domain	-	-	-	-	-	-	-	-	-	-	-	-	Secretin
CH2_k127_6233312_2	1163617.SCD_n01091	4.898e-41	152.0	COG1940@1|root,COG1940@2|Bacteria,1MU94@1224|Proteobacteria,2VMGT@28216|Betaproteobacteria	28216|Betaproteobacteria	GK	ROK family	nagK	-	2.7.1.2,2.7.1.4,2.7.1.59	ko:K00845,ko:K00847,ko:K00884	ko00010,ko00051,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00051,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R00760,R00867,R01201,R01600,R01786,R03920	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
CH2_k127_6233312_4	1049564.TevJSym_as00590	1.108e-15	79.0	2ESGD@1|root,33K13@2|Bacteria,1NGAC@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_6233312_1	479434.Sthe_0453	8.217e-86	292.0	COG1409@1|root,COG1409@2|Bacteria,2G88X@200795|Chloroflexi,27Z25@189775|Thermomicrobia	189775|Thermomicrobia	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
CH2_k127_6233312_3	1349767.GJA_3889	4.601e-25	112.0	COG3012@1|root,COG3318@1|root,COG3012@2|Bacteria,COG3318@2|Bacteria,1R4KR@1224|Proteobacteria,2VSZR@28216|Betaproteobacteria,476BF@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Uncharacterised protein family (UPF0149)	-	-	-	ko:K07039	-	-	-	-	ko00000	-	-	-	SEC-C,UPF0149
CH2_k127_6233312_0	1163617.SCD_n01089	4.042e-93	307.0	COG2716@1|root,COG2716@2|Bacteria,1R7W7@1224|Proteobacteria	1224|Proteobacteria	E	Glycine cleavage system	gcvR	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576	-	ko:K03567	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	ACT_6
CH2_k127_6244268_7	1163617.SCD_n00321	4.666e-08	56.0	2EI92@1|root,33C0E@2|Bacteria,1NHN6@1224|Proteobacteria,2VYC9@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_6244268_3	1163617.SCD_n02085	1.389e-48	176.0	2E0WU@1|root,32VAZ@2|Bacteria,1N42K@1224|Proteobacteria,2W4VG@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_6244268_6	1278309.KB907102_gene148	7.42e-24	106.0	COG2827@1|root,COG2827@2|Bacteria,1N6PA@1224|Proteobacteria,1SCBH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	endonuclease containing a URI domain	yhbQ	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
CH2_k127_6244268_0	1163617.SCD_n00017	2.384e-144	463.0	28I2K@1|root,2Z86N@2|Bacteria,1R1GA@1224|Proteobacteria,2VPIS@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_6244268_4	395494.Galf_2052	6.812e-44	165.0	COG0664@1|root,COG0664@2|Bacteria,1NBX3@1224|Proteobacteria,2W9TM@28216|Betaproteobacteria,44WMM@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Transcriptional regulator, Crp Fnr family	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
CH2_k127_6244268_5	1163617.SCD_n02180	9.107e-35	133.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2VVTG@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Cold shock protein	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
CH2_k127_6244268_1	1163617.SCD_n02175	1.07e-59	208.0	COG0023@1|root,COG0023@2|Bacteria,1MZ8T@1224|Proteobacteria,2VU7V@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Translation initiation factor	yciH	-	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
CH2_k127_6244268_2	1163617.SCD_n00536	1.176e-54	194.0	COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,2VH21@28216|Betaproteobacteria	28216|Betaproteobacteria	L	a g-specific adenine glycosylase	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
CH2_k127_6277030_8	1163617.SCD_n01865	2.599e-79	286.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VNJW@28216|Betaproteobacteria	28216|Betaproteobacteria	NT	histidine kinase HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,TarH
CH2_k127_6277030_5	1163617.SCD_n01224	1.055e-138	450.0	COG5000@1|root,COG5000@2|Bacteria,1QUG9@1224|Proteobacteria,2WGTY@28216|Betaproteobacteria	28216|Betaproteobacteria	T	signal transduction histidine kinase	-	-	2.7.13.3	ko:K10942	ko02020,ko05111,map02020,map05111	M00515	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_8
CH2_k127_6277030_2	1163617.SCD_n01225	2.293e-190	603.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria	28216|Betaproteobacteria	T	response regulator	fleR	-	-	ko:K10943	ko02020,ko05111,map02020,map05111	M00515	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CH2_k127_6277030_17	1163617.SCD_n01226	3.371e-30	123.0	COG1677@1|root,COG1677@2|Bacteria,1N6RZ@1224|Proteobacteria,2VVQF@28216|Betaproteobacteria	28216|Betaproteobacteria	N	Flagellar hook-basal body complex protein FliE	fliE	-	-	ko:K02408	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliE
CH2_k127_6277030_1	1163617.SCD_n01227	1.152e-223	704.0	COG1766@1|root,COG1766@2|Bacteria,1MUQR@1224|Proteobacteria,2VI9M@28216|Betaproteobacteria	28216|Betaproteobacteria	N	The M ring may be actively involved in energy transduction	fliF	-	-	ko:K02409	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	YscJ_FliF,YscJ_FliF_C
CH2_k127_6277030_4	1286093.C266_19905	3.537e-139	449.0	COG1536@1|root,COG1536@2|Bacteria,1MV9X@1224|Proteobacteria,2VI19@28216|Betaproteobacteria,1K4Q4@119060|Burkholderiaceae	28216|Betaproteobacteria	N	flagellar motor switch protein flig	fliG	-	-	ko:K02410	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliG_C,FliG_M,FliG_N
CH2_k127_6277030_10	640081.Dsui_1754	7.41e-49	181.0	COG1317@1|root,COG1317@2|Bacteria,1NMQE@1224|Proteobacteria,2VSQ0@28216|Betaproteobacteria,2KWS2@206389|Rhodocyclales	206389|Rhodocyclales	N	Flagellar assembly protein FliH	-	-	-	ko:K02411	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliH
CH2_k127_6277030_0	1163617.SCD_n01230	4.119e-227	711.0	COG1157@1|root,COG1157@2|Bacteria,1MUH6@1224|Proteobacteria,2VHQ5@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	PFAM H transporting two-sector ATPase alpha beta subunit central region	fliI	-	3.6.3.14	ko:K02412	ko02040,map02040	-	-	-	ko00000,ko00001,ko01000,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	ATP-synt_ab,ATP-synt_ab_N
CH2_k127_6277030_12	1163617.SCD_n01231	4.818e-41	156.0	COG2882@1|root,COG2882@2|Bacteria,1RHFM@1224|Proteobacteria,2VVBH@28216|Betaproteobacteria	28216|Betaproteobacteria	N	Flagellar export protein FliJ	fliJ	-	-	ko:K02413	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliJ
CH2_k127_6277030_13	1163617.SCD_n01232	1.945e-38	159.0	COG3144@1|root,COG3144@2|Bacteria,1N7XT@1224|Proteobacteria,2VU2D@28216|Betaproteobacteria	28216|Betaproteobacteria	N	Flagellar hook-length control protein	fliK	-	-	ko:K02414	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_hook
CH2_k127_6277030_15	1163617.SCD_n01233	2.715e-33	135.0	COG1580@1|root,COG1580@2|Bacteria,1RARK@1224|Proteobacteria,2VTXC@28216|Betaproteobacteria	28216|Betaproteobacteria	N	Controls the rotational direction of flagella during chemotaxis	fliL	-	-	ko:K02415	-	-	-	-	ko00000,ko02035	-	-	-	FliL
CH2_k127_6277030_3	1163617.SCD_n01234	3.596e-166	527.0	COG1868@1|root,COG1868@2|Bacteria,1MX01@1224|Proteobacteria,2VI0A@28216|Betaproteobacteria	28216|Betaproteobacteria	N	Flagellar motor switch protein	fliM	-	-	ko:K02416	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliM,FliMN_C
CH2_k127_6277030_9	1163617.SCD_n01235	1.391e-57	204.0	COG1886@1|root,COG1886@2|Bacteria,1RGWT@1224|Proteobacteria,2VSZ7@28216|Betaproteobacteria	28216|Betaproteobacteria	N	Flagellar motor switch protein flin	fliN	-	-	ko:K02417,ko:K03225	ko02030,ko02040,ko03070,map02030,map02040,map03070	M00332,M00542,M00660	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.6.1,3.A.6.2,3.A.6.3	-	-	FliMN_C
CH2_k127_6277030_14	1163617.SCD_n01236	5.128e-35	139.0	COG3190@1|root,COG3190@2|Bacteria,1PQ30@1224|Proteobacteria,2VWHP@28216|Betaproteobacteria	28216|Betaproteobacteria	N	PFAM flagellar biosynthesis protein, FliO	fliO	-	-	ko:K02418	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliO
CH2_k127_6277030_6	1163617.SCD_n01237	1.04e-109	362.0	COG1338@1|root,COG1338@2|Bacteria,1MVBU@1224|Proteobacteria,2VIU6@28216|Betaproteobacteria	28216|Betaproteobacteria	N	Plays a role in the flagellum-specific transport system	fliP	-	-	ko:K02419	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliP
CH2_k127_6277030_16	1163617.SCD_n01238	5.38e-32	126.0	COG1987@1|root,COG1987@2|Bacteria,1N73W@1224|Proteobacteria,2VU8S@28216|Betaproteobacteria	28216|Betaproteobacteria	N	Role in flagellar biosynthesis	fliQ	-	-	ko:K02420	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_3
CH2_k127_6277030_7	1163617.SCD_n01239	1.864e-97	325.0	COG1684@1|root,COG1684@2|Bacteria,1NIF4@1224|Proteobacteria,2VQ64@28216|Betaproteobacteria	28216|Betaproteobacteria	N	Flagellar biosynthetic protein FliR	fliR	-	-	ko:K02421	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_1
CH2_k127_6277030_11	76114.ebA6822	1.165e-46	172.0	COG0500@1|root,COG0500@2|Bacteria,1QU9M@1224|Proteobacteria,2WGK0@28216|Betaproteobacteria,2KWMJ@206389|Rhodocyclales	206389|Rhodocyclales	Q	tellurite resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25
CH2_k127_6287941_1	1163617.SCD_n00861	2.916e-193	615.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria	28216|Betaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.9	ko:K01539	ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978	-	-	-	ko00000,ko00001,ko01000,ko04147	3.A.3.1	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
CH2_k127_6287941_0	1163617.SCD_n00862	3.511e-208	658.0	COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,2VJA4@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
CH2_k127_6287941_4	1163617.SCD_n01304	2.791e-33	132.0	COG3905@1|root,COG3905@2|Bacteria,1N7SQ@1224|Proteobacteria,2VVRJ@28216|Betaproteobacteria	28216|Betaproteobacteria	K	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_6287941_3	1163617.SCD_n01303	6.972e-45	165.0	COG3668@1|root,COG3668@2|Bacteria,1N016@1224|Proteobacteria,2VVYK@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Plasmid stabilization system	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
CH2_k127_6287941_2	1163617.SCD_n00872	5.441e-78	264.0	COG0477@1|root,COG2814@2|Bacteria,1MVZI@1224|Proteobacteria,2VHWT@28216|Betaproteobacteria	28216|Betaproteobacteria	EGP	Major facilitator Superfamily	hcaT	-	-	ko:K05820	-	-	-	-	ko00000,ko02000	2.A.1.27	-	-	MFS_1_like
CH2_k127_63151_1	1163617.SCD_n00064	3.624e-251	779.0	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,2VQUN@28216|Betaproteobacteria	28216|Betaproteobacteria	T	'signal transduction protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
CH2_k127_63151_0	1163617.SCD_n00063	0.0	1229.0	COG3170@1|root,COG3170@2|Bacteria,1QV1N@1224|Proteobacteria,2WGRZ@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	Protein of unknown function (DUF1631)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1631
CH2_k127_63151_3	316057.RPD_1049	6.026e-165	528.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,2TUHD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	alcohol dehydrogenase	-	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
CH2_k127_63151_2	1123392.AQWL01000005_gene3075	4.647e-165	535.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VJMN@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	DUF2222,EAL,GGDEF,HAMP,PAS,PAS_3,PAS_4,PAS_9
CH2_k127_63151_4	243233.MCA0866	3.489e-50	182.0	COG1032@1|root,COG1032@2|Bacteria,1Q5NG@1224|Proteobacteria,1RQCS@1236|Gammaproteobacteria,1XG8E@135618|Methylococcales	135618|Methylococcales	C	Protein of unknown function (DUF4080)	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4080,Radical_SAM
CH2_k127_6340708_3	1163617.SCD_n00890	2.357e-64	222.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,2WGGJ@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	metZ	-	2.5.1.48	ko:K01739,ko:K10764	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
CH2_k127_6340708_7	1163617.SCD_n01837	4.107e-21	94.0	COG2608@1|root,COG2608@2|Bacteria,1NGBD@1224|Proteobacteria,2VXV9@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Heavy metal-associated domain protein	copZ	-	-	ko:K07213	ko04978,map04978	-	-	-	ko00000,ko00001	-	-	-	HMA
CH2_k127_6340708_0	1163617.SCD_n01830	0.0	1055.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2VH8J@28216|Betaproteobacteria	28216|Betaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copA	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
CH2_k127_6340708_2	1123368.AUIS01000019_gene1195	5.19e-115	379.0	COG2199@1|root,COG3706@2|Bacteria,1R7KA@1224|Proteobacteria,1RS1K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	ydeH	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0007155,GO:0008150,GO:0008270,GO:0009987,GO:0010639,GO:0016740,GO:0016772,GO:0016779,GO:0022610,GO:0031344,GO:0031345,GO:0031589,GO:0032879,GO:0033043,GO:0042710,GO:0042802,GO:0043167,GO:0043169,GO:0043708,GO:0043709,GO:0043900,GO:0043902,GO:0044010,GO:0044087,GO:0044464,GO:0044764,GO:0046872,GO:0046914,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051270,GO:0051271,GO:0051704,GO:0052621,GO:0060187,GO:0060491,GO:0065007,GO:0090605,GO:0090609,GO:1900190,GO:1900192,GO:1900231,GO:1900233,GO:1902115,GO:1902116,GO:1902208,GO:1902209	2.7.7.65	ko:K13069	-	-	R08057	-	ko00000,ko01000	-	-	-	CZB,GGDEF
CH2_k127_6340708_4	1123368.AUIS01000019_gene1194	5.279e-56	204.0	COG1776@1|root,COG1776@2|Bacteria,1N4CX@1224|Proteobacteria	1224|Proteobacteria	NT	PFAM CheC domain protein	cheC	-	-	ko:K03410	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheC
CH2_k127_6340708_6	667632.KB890220_gene2838	7.343e-47	171.0	COG0784@1|root,COG0784@2|Bacteria,1QTXY@1224|Proteobacteria,2VUES@28216|Betaproteobacteria,1K7VS@119060|Burkholderiaceae	28216|Betaproteobacteria	T	Pfam Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CH2_k127_6340708_1	1163617.SCD_n00906	2.006e-199	642.0	COG5001@1|root,COG5002@1|root,COG5001@2|Bacteria,COG5002@2|Bacteria,1MU2C@1224|Proteobacteria,2W14J@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4
CH2_k127_6353387_1	1304883.KI912532_gene2462	3.213e-80	272.0	COG0546@1|root,COG0546@2|Bacteria,1RDA7@1224|Proteobacteria,2VIZ2@28216|Betaproteobacteria,2KVFF@206389|Rhodocyclales	206389|Rhodocyclales	S	HAD-superfamily hydrolase	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
CH2_k127_6353387_0	1163617.SCD_n01544	5.506e-147	470.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,2VH94@28216|Betaproteobacteria	28216|Betaproteobacteria	OU	peptidase, S49	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
CH2_k127_6454078_2	1123392.AQWL01000004_gene2766	4.064e-80	269.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,2VIEV@28216|Betaproteobacteria,1KRAY@119069|Hydrogenophilales	119069|Hydrogenophilales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
CH2_k127_6454078_5	1163617.SCD_n00556	1.522e-41	160.0	COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,2VU5H@28216|Betaproteobacteria	28216|Betaproteobacteria	J	sigma 54 modulation protein ribosomal protein S30EA	raiA	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
CH2_k127_6454078_3	85643.Tmz1t_0706	4.289e-57	203.0	COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,2VRDH@28216|Betaproteobacteria,2KW4R@206389|Rhodocyclales	206389|Rhodocyclales	G	COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)	ptsN	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS_EIIA_2
CH2_k127_6454078_0	1163617.SCD_n00554	4.958e-130	421.0	COG1493@1|root,COG1493@2|Bacteria,1NNN5@1224|Proteobacteria,2VJCH@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
CH2_k127_6454078_1	1163617.SCD_n00553	1.022e-128	415.0	COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,2VIH5@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Displays ATPase and GTPase activities	yhbJ	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
CH2_k127_6454078_4	1163617.SCD_n00552	1.626e-48	182.0	COG5341@1|root,COG5341@2|Bacteria,1N1PN@1224|Proteobacteria,2VUW8@28216|Betaproteobacteria	28216|Betaproteobacteria	S	NusG domain II	-	-	-	-	-	-	-	-	-	-	-	-	NusG_II
CH2_k127_6610608_0	1485544.JQKP01000002_gene1657	8.227e-106	350.0	COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,2VHI1@28216|Betaproteobacteria,44V8U@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
CH2_k127_6610608_1	1163617.SCD_n02500	1.169e-93	319.0	COG3107@1|root,COG3107@2|Bacteria,1MUHR@1224|Proteobacteria,2VSUT@28216|Betaproteobacteria	28216|Betaproteobacteria	M	LppC putative lipoprotein	-	-	-	ko:K07121	-	-	-	-	ko00000	-	-	-	LppC
CH2_k127_6610608_4	1288494.EBAPG3_5290	4.874e-38	146.0	COG0792@1|root,COG0792@2|Bacteria,1N6VN@1224|Proteobacteria,2VU20@28216|Betaproteobacteria,373I0@32003|Nitrosomonadales	28216|Betaproteobacteria	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
CH2_k127_6610608_2	1163617.SCD_n02502	2.405e-93	309.0	COG0279@1|root,COG0279@2|Bacteria,1NJ8X@1224|Proteobacteria,2VN12@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
CH2_k127_6610608_3	1163617.SCD_n02503	7.193e-71	244.0	COG2823@1|root,COG2823@2|Bacteria,1MUZ2@1224|Proteobacteria,2VQIS@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM transport-associated	-	-	-	-	-	-	-	-	-	-	-	-	BON
CH2_k127_6671526_2	1163617.SCD_n02139	9.073e-148	469.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,2VIVB@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
CH2_k127_6671526_8	265072.Mfla_2241	1.206e-25	108.0	COG3339@1|root,COG3339@2|Bacteria,1MZCY@1224|Proteobacteria,2VV31@28216|Betaproteobacteria,2KN8M@206350|Nitrosomonadales	206350|Nitrosomonadales	P	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
CH2_k127_6671526_1	1163617.SCD_n01997	3.696e-170	538.0	COG0861@1|root,COG0861@2|Bacteria,1MUNR@1224|Proteobacteria,2VJB9@28216|Betaproteobacteria	28216|Betaproteobacteria	P	membrane protein, terc	ygjT	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
CH2_k127_6671526_3	864051.BurJ1DRAFT_4600	1.508e-80	286.0	COG0810@1|root,COG3064@1|root,COG0810@2|Bacteria,COG3064@2|Bacteria,1REKC@1224|Proteobacteria,2VRYT@28216|Betaproteobacteria	28216|Betaproteobacteria	M	TonB C terminal	-	-	-	-	-	-	-	-	-	-	-	-	TonB_2
CH2_k127_6671526_4	1163617.SCD_n01275	5.012e-78	262.0	COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,2VRG9@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
CH2_k127_6671526_5	582744.Msip34_1230	2.817e-53	191.0	COG2867@1|root,COG2867@2|Bacteria,1RGUH@1224|Proteobacteria,2VR4X@28216|Betaproteobacteria,2KMT8@206350|Nitrosomonadales	206350|Nitrosomonadales	I	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
CH2_k127_6671526_7	1485544.JQKP01000003_gene136	1.367e-34	136.0	COG2914@1|root,COG2914@2|Bacteria,1MZCH@1224|Proteobacteria,2VVNX@28216|Betaproteobacteria,44VZ5@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Belongs to the UPF0125 (RnfH) family	rnfH	-	-	ko:K09801	-	-	-	-	ko00000	-	-	-	Ub-RnfH
CH2_k127_6671526_6	1485544.JQKP01000019_gene8	1.554e-44	184.0	COG3170@1|root,COG3170@2|Bacteria	2|Bacteria	NU	translation initiation factor activity	-	-	-	ko:K08086	-	-	-	-	ko00000	-	-	-	-
CH2_k127_6671526_10	1163617.SCD_n01279	7.381e-20	94.0	29460@1|root,2ZRKG@2|Bacteria,1PBM2@1224|Proteobacteria,2W5WD@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	ko:K06078	-	-	-	-	ko00000,ko01011	-	-	-	-
CH2_k127_6671526_0	1163617.SCD_n01280	1.152e-225	703.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,2VH9X@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
CH2_k127_6718236_3	396588.Tgr7_2207	3.371e-101	334.0	COG1856@1|root,COG1856@2|Bacteria,1R6PW@1224|Proteobacteria,1SKHD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	SMART Elongator protein 3 MiaB NifB	-	-	-	ko:K09711	-	-	-	-	ko00000	-	-	-	Radical_SAM
CH2_k127_6718236_5	396595.TK90_0640	3.398e-66	229.0	COG0509@1|root,COG0509@2|Bacteria,1RKRS@1224|Proteobacteria,1T0BR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	-	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
CH2_k127_6718236_4	1163617.SCD_n00800	1.041e-96	319.0	COG2210@1|root,COG2210@2|Bacteria,1RDUG@1224|Proteobacteria,2VS0Z@28216|Betaproteobacteria	28216|Betaproteobacteria	S	DsrE/DsrF/DrsH-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
CH2_k127_6718236_6	1163617.SCD_n00799	3.62e-35	135.0	COG0425@1|root,COG0425@2|Bacteria,1MZA5@1224|Proteobacteria,2VVW5@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Belongs to the sulfur carrier protein TusA family	-	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	TusA
CH2_k127_6718236_7	1163617.SCD_n00798	4.218e-29	120.0	COG0607@1|root,COG0607@2|Bacteria,1N4EA@1224|Proteobacteria	1224|Proteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CH2_k127_6718236_2	1123393.KB891328_gene613	1.488e-112	370.0	COG3302@1|root,COG3302@2|Bacteria,1MWY1@1224|Proteobacteria,2VN4W@28216|Betaproteobacteria,1KSJJ@119069|Hydrogenophilales	119069|Hydrogenophilales	S	DMSO reductase anchor subunit (DmsC)	-	-	-	-	-	-	-	-	-	-	-	-	DmsC
CH2_k127_6718236_1	1123393.KB891328_gene612	5.083e-132	426.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,2VKVM@28216|Betaproteobacteria,1KS8J@119069|Hydrogenophilales	119069|Hydrogenophilales	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_11
CH2_k127_6718236_0	1123393.KB891328_gene611	5e-324	993.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,2VKSY@28216|Betaproteobacteria,1KSF4@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	1.8.5.6	ko:K21307	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R11487	RC00168	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CH2_k127_6776724_4	1163617.SCD_n01751	1.362e-40	151.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2VJDZ@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
CH2_k127_6776724_6	765912.Thimo_0302	3.401e-16	80.0	COG5450@1|root,COG5450@2|Bacteria,1N76R@1224|Proteobacteria,1SD4N@1236|Gammaproteobacteria,1WZP4@135613|Chromatiales	135613|Chromatiales	K	Bacterial antitoxin of type II TA system, VapB	-	-	-	-	-	-	-	-	-	-	-	-	VapB_antitoxin
CH2_k127_6776724_2	237368.SCABRO_02088	7.748e-48	174.0	COG1487@1|root,COG1487@2|Bacteria	2|Bacteria	S	nuclease activity	vapC	GO:0001666,GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0036293,GO:0040008,GO:0043170,GO:0043207,GO:0044237,GO:0044238,GO:0044403,GO:0044419,GO:0045926,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051701,GO:0051704,GO:0051707,GO:0060255,GO:0065007,GO:0070482,GO:0071704,GO:0075136,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:2000112,GO:2000113	-	-	-	-	-	-	-	-	-	-	PIN
CH2_k127_6776724_0	1163617.SCD_n01752	6.82e-175	551.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,2VJ5G@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Pfam Glycosyl transferase family 2	arnC	-	2.4.2.53	ko:K10012	ko00520,ko01503,map00520,map01503	M00721,M00761	R07661	RC00005,RC02954	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	4.D.2.1.8	GT2	-	Glycos_transf_2
CH2_k127_6776724_5	269799.Gmet_2973	2.748e-31	124.0	COG3549@1|root,COG3549@2|Bacteria,1MZKX@1224|Proteobacteria,42VG7@68525|delta/epsilon subdivisions,2WRNJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Plasmid maintenance system killer	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
CH2_k127_6776724_3	292415.Tbd_0672	8.497e-44	161.0	COG3093@1|root,COG3093@2|Bacteria,1N76J@1224|Proteobacteria,2VUG3@28216|Betaproteobacteria	28216|Betaproteobacteria	K	plasmid maintenance system antidote protein	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
CH2_k127_6776724_1	261292.Nit79A3_2738	9.284e-51	182.0	COG1715@1|root,COG1715@2|Bacteria,1Q2VY@1224|Proteobacteria,2VPK0@28216|Betaproteobacteria,3735T@32003|Nitrosomonadales	28216|Betaproteobacteria	V	Restriction endonuclease	-	-	-	ko:K07448	-	-	-	-	ko00000,ko02048	-	-	-	Mrr_N,Mrr_cat
CH2_k127_6794394_3	1163617.SCD_n02139	8.36e-34	130.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,2VIVB@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
CH2_k127_6794394_2	1163617.SCD_n02140	8.109e-93	307.0	COG2862@1|root,COG2862@2|Bacteria,1RFUX@1224|Proteobacteria,2VRH2@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Uncharacterized protein family, UPF0114	-	-	-	-	-	-	-	-	-	-	-	-	UPF0114
CH2_k127_6794394_1	1163617.SCD_n02142	1.204e-176	557.0	COG0583@1|root,COG0583@2|Bacteria,1MVHT@1224|Proteobacteria,2VHF0@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	ko:K03717	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
CH2_k127_6794394_0	1288494.EBAPG3_26340	4.9e-181	573.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,2VHTE@28216|Betaproteobacteria,371N0@32003|Nitrosomonadales	28216|Betaproteobacteria	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
CH2_k127_688590_2	1163617.SCD_n00098	2.204e-50	183.0	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,2VK0Y@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
CH2_k127_688590_0	1163617.SCD_n00097	1.43e-208	650.0	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,2VIR9@28216|Betaproteobacteria	28216|Betaproteobacteria	D	Cell shape determining protein, MreB Mrl family	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
CH2_k127_688590_3	265072.Mfla_2490	2.626e-37	142.0	COG0721@1|root,COG0721@2|Bacteria,1MZQP@1224|Proteobacteria,2VUFB@28216|Betaproteobacteria,2KN54@206350|Nitrosomonadales	206350|Nitrosomonadales	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
CH2_k127_688590_1	1163617.SCD_n00095	2.379e-165	524.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2VIG3@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
CH2_k127_6930356_2	1163617.SCD_n01542	9.796e-83	281.0	COG0313@1|root,COG0313@2|Bacteria,1RARW@1224|Proteobacteria,2VQ34@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Uroporphyrin-iii c tetrapyrrole (Corrin porphyrin) methyltransferase	rsmI_2	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
CH2_k127_6930356_3	1163617.SCD_n01541	5.314e-81	274.0	COG0424@1|root,COG0424@2|Bacteria,1RDA9@1224|Proteobacteria,2VQUQ@28216|Betaproteobacteria	28216|Betaproteobacteria	D	Maf-like protein	yceF	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
CH2_k127_6930356_0	1163617.SCD_n01540	0.0	1003.0	COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,1QTTG@1224|Proteobacteria,2VKZP@28216|Betaproteobacteria	28216|Betaproteobacteria	C	TIGRFAM Oxaloacetate decarboxylase, alpha subunit	-	-	6.4.1.1	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl,HMGL-like,PYC_OADA
CH2_k127_6930356_1	1163617.SCD_n01539	6.512e-275	850.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,2WH9U@28216|Betaproteobacteria	28216|Betaproteobacteria	I	acetyl-CoA carboxylase, biotin carboxylase	-	-	6.4.1.1	ko:K01959	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173,M00620	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
CH2_k127_6930356_5	395494.Galf_1556	1.189e-35	141.0	COG1399@1|root,COG1399@2|Bacteria,1PIWK@1224|Proteobacteria,2W7FZ@28216|Betaproteobacteria,44VYP@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
CH2_k127_6930356_6	582744.Msip34_1390	1.951e-29	117.0	COG0333@1|root,COG0333@2|Bacteria,1N6RF@1224|Proteobacteria,2VVP5@28216|Betaproteobacteria,2KN4T@206350|Nitrosomonadales	206350|Nitrosomonadales	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
CH2_k127_6930356_4	1163617.SCD_n01536	6.718e-45	165.0	COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,2VI25@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
CH2_k127_6943295_1	1163617.SCD_n02782	3.631e-67	230.0	COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,2VIT9@28216|Betaproteobacteria	28216|Betaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
CH2_k127_6943295_2	292415.Tbd_0177	5.303e-62	215.0	COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,2VSD7@28216|Betaproteobacteria	28216|Betaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
CH2_k127_6943295_0	1288494.EBAPG3_5470	5.429e-202	634.0	COG0403@1|root,COG0403@2|Bacteria,1MVC1@1224|Proteobacteria,2VKQB@28216|Betaproteobacteria,3720Y@32003|Nitrosomonadales	28216|Betaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
CH2_k127_6955743_6	439481.Aboo_0807	8.122e-78	269.0	COG1894@1|root,arCOG04537@2157|Archaea,2XUYN@28890|Euryarchaeota,3F337@33867|unclassified Euryarchaeota	28890|Euryarchaeota	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	1.12.1.3,1.6.5.3	ko:K00335,ko:K18331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
CH2_k127_6955743_8	742738.HMPREF9460_00004	3.467e-15	81.0	COG1905@1|root,COG1905@2|Bacteria,1VBFB@1239|Firmicutes,24PJH@186801|Clostridia	186801|Clostridia	C	PFAM Respiratory-chain NADH dehydrogenase 24 Kd subunit	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
CH2_k127_6955743_2	204773.HEAR0393	2.008e-128	415.0	COG2116@1|root,COG2116@2|Bacteria,1MU0W@1224|Proteobacteria,2VKMF@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Formate nitrite	-	-	-	ko:K02598,ko:K06212	-	-	-	-	ko00000,ko02000	1.A.16.1.1,1.A.16.1.3,1.A.16.3	-	-	Form_Nir_trans
CH2_k127_6955743_4	857087.Metme_1600	2.337e-92	319.0	COG0642@1|root,COG0642@2|Bacteria,1MX6R@1224|Proteobacteria,1RPMH@1236|Gammaproteobacteria,1XGYU@135618|Methylococcales	135618|Methylococcales	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
CH2_k127_6955743_5	857087.Metme_1599	2.374e-83	282.0	COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,1RMWT@1236|Gammaproteobacteria,1XDXZ@135618|Methylococcales	135618|Methylococcales	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CH2_k127_6955743_1	864051.BurJ1DRAFT_1174	2.179e-161	515.0	2EMF3@1|root,2ZKNW@2|Bacteria,1RAZA@1224|Proteobacteria,2VQE2@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PEP-CTERM motif	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
CH2_k127_6955743_3	572477.Alvin_1370	1.925e-94	322.0	COG0745@1|root,COG0745@2|Bacteria,1R52E@1224|Proteobacteria,1RRNC@1236|Gammaproteobacteria,1WXDS@135613|Chromatiales	135613|Chromatiales	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CH2_k127_6955743_0	697282.Mettu_0660	9.938e-220	738.0	COG0784@1|root,COG2202@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,1SVEC@1236|Gammaproteobacteria,1XH1G@135618|Methylococcales	135618|Methylococcales	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
CH2_k127_6955743_7	1163617.SCD_n00732	7.206e-51	187.0	COG1807@1|root,COG1807@2|Bacteria,1PUE3@1224|Proteobacteria,2VHPU@28216|Betaproteobacteria	28216|Betaproteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CH2_k127_7035918_0	1163617.SCD_n02194	1.021e-151	483.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,2VHXG@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
CH2_k127_7035918_1	1266925.JHVX01000005_gene2009	7.019e-131	425.0	COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,2VHQV@28216|Betaproteobacteria,3724A@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Belongs to the FPP GGPP synthase family	ispA	-	2.5.1.1,2.5.1.10	ko:K00795	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364	R01658,R02003	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
CH2_k127_7035918_6	1163617.SCD_n02196	4.855e-23	100.0	COG1722@1|root,COG1722@2|Bacteria,1PTYP@1224|Proteobacteria,2VVQV@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
CH2_k127_7035918_3	1163617.SCD_n02197	1.336e-108	358.0	COG0697@1|root,COG0697@2|Bacteria,1MZXM@1224|Proteobacteria,2VK90@28216|Betaproteobacteria	28216|Betaproteobacteria	EG	of the drug metabolite transporter (DMT) superfamily	-	-	-	ko:K15270	-	-	-	-	ko00000,ko02000	2.A.7.3.7	-	-	EamA
CH2_k127_7035918_4	395494.Galf_2274	8.728e-41	153.0	2CU7M@1|root,32SUS@2|Bacteria,1N1WF@1224|Proteobacteria,2VUS0@28216|Betaproteobacteria,44VVW@713636|Nitrosomonadales	28216|Betaproteobacteria	S	SpoIIAA-like	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIAA-like
CH2_k127_7035918_5	1163617.SCD_n02199	8.373e-37	142.0	2E0X2@1|root,32WE0@2|Bacteria,1R38G@1224|Proteobacteria,2VV4E@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of Unknown function (DUF2784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2784
CH2_k127_7035918_2	1163617.SCD_n01357	5.84e-120	392.0	COG5660@1|root,32WII@2|Bacteria,1R3ME@1224|Proteobacteria	1224|Proteobacteria	S	TRAP transporter T-component	-	-	-	-	-	-	-	-	-	-	-	-	TAtT
CH2_k127_7091100_3	580332.Slit_1529	6.687e-138	444.0	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,2VJF7@28216|Betaproteobacteria,44V99@713636|Nitrosomonadales	28216|Betaproteobacteria	I	TIGRFAM malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645,ko:K13935,ko:K15355	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
CH2_k127_7091100_4	1163617.SCD_n01533	1.588e-115	376.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,2VJ3S@28216|Betaproteobacteria	28216|Betaproteobacteria	IQ	reductase	fabG	GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CH2_k127_7091100_9	265072.Mfla_1504	9.923e-36	136.0	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,2VTZH@28216|Betaproteobacteria,2KN5P@206350|Nitrosomonadales	206350|Nitrosomonadales	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
CH2_k127_7091100_0	1163617.SCD_n01531	7.521e-228	710.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,2VI6I@28216|Betaproteobacteria	28216|Betaproteobacteria	I	catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-acp	fabF	GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817	2.3.1.179	ko:K00646,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
CH2_k127_7091100_1	748280.NH8B_3234	1.018e-147	479.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,2VKGH@28216|Betaproteobacteria,2KQJY@206351|Neisseriales	206351|Neisseriales	EH	Anthranilate synthase	-	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
CH2_k127_7091100_6	1163617.SCD_n01529	3.13e-94	316.0	COG0115@1|root,COG0115@2|Bacteria,1MZAK@1224|Proteobacteria,2VRAS@28216|Betaproteobacteria	28216|Betaproteobacteria	EH	PFAM Aminotransferase, class IV	pabC	-	4.1.3.38	ko:K02619	ko00790,map00790	-	R05553	RC01843,RC02148	ko00000,ko00001,ko01000	-	-	-	Aminotran_4
CH2_k127_7091100_2	1163617.SCD_n01528	1.219e-140	453.0	COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,2VHD4@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
CH2_k127_7091100_7	580332.Slit_1535	9.281e-76	263.0	COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,2VQ24@28216|Betaproteobacteria,44VRC@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
CH2_k127_7091100_5	1163617.SCD_n01526	6.405e-106	353.0	COG0470@1|root,COG0470@2|Bacteria,1MY1W@1224|Proteobacteria,2VNED@28216|Betaproteobacteria	28216|Betaproteobacteria	L	dna polymerase iii	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
CH2_k127_7091100_8	1123393.KB891333_gene2569	2.986e-39	147.0	COG3215@1|root,COG3215@2|Bacteria,1RGWZ@1224|Proteobacteria,2VT2B@28216|Betaproteobacteria,1KT2J@119069|Hydrogenophilales	119069|Hydrogenophilales	NU	PilZ domain	-	-	-	ko:K02676	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilZ
CH2_k127_7119799_2	1266925.JHVX01000003_gene468	1.607e-95	321.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,2VHBW@28216|Betaproteobacteria,371TQ@32003|Nitrosomonadales	28216|Betaproteobacteria	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
CH2_k127_7119799_0	1288494.EBAPG3_760	1.673e-174	555.0	COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,2VHJY@28216|Betaproteobacteria,3723X@32003|Nitrosomonadales	28216|Betaproteobacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
CH2_k127_7119799_3	1163617.SCD_n01630	1.032e-68	246.0	COG0575@1|root,COG0575@2|Bacteria,1MWSV@1224|Proteobacteria,2VMM0@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
CH2_k127_7119799_1	1288494.EBAPG3_780	3.048e-118	384.0	COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,2VH2E@28216|Betaproteobacteria,3721N@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
CH2_k127_7119799_4	335283.Neut_2032	5.113e-07	51.0	COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,2VIUA@28216|Betaproteobacteria,3722X@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
CH2_k127_713375_2	1266925.JHVX01000007_gene2305	2.511e-11	64.0	COG4591@1|root,COG4591@2|Bacteria,1R4Q2@1224|Proteobacteria,2VKX2@28216|Betaproteobacteria,371YH@32003|Nitrosomonadales	28216|Betaproteobacteria	M	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CH2_k127_713375_0	582744.Msip34_2343	1.03e-168	539.0	COG0477@1|root,COG2814@2|Bacteria,1QTWR@1224|Proteobacteria,2VIC5@28216|Betaproteobacteria,2KPAT@206350|Nitrosomonadales	206350|Nitrosomonadales	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CH2_k127_713375_1	1163617.SCD_n01589	1.106e-138	446.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,2VIX7@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CH2_k127_7184861_1	1288494.EBAPG3_9250	4.847e-65	227.0	COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,2VRD3@28216|Betaproteobacteria,37364@32003|Nitrosomonadales	28216|Betaproteobacteria	L	Conserved hypothetical protein 95	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
CH2_k127_7184861_0	1120999.JONM01000009_gene371	8.429e-94	328.0	2AAP7@1|root,31015@2|Bacteria,1RDTH@1224|Proteobacteria,2VR2B@28216|Betaproteobacteria,2KR6K@206351|Neisseriales	206351|Neisseriales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_7184861_2	1117647.M5M_00060	1.796e-22	102.0	COG0226@1|root,COG0226@2|Bacteria,1N7RX@1224|Proteobacteria,1S97W@1236|Gammaproteobacteria,1J70Y@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	COG0226 ABC-type phosphate transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	PBP_like_2
CH2_k127_7206206_2	706587.Desti_3899	2.255e-71	258.0	COG0515@1|root,COG0664@1|root,COG0515@2|Bacteria,COG0664@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2MRS2@213462|Syntrophobacterales	28221|Deltaproteobacteria	KLT	PFAM Protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_8,cNMP_binding
CH2_k127_7206206_0	1163617.SCD_n02474	0.0	1450.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,2VHDH@28216|Betaproteobacteria	28216|Betaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
CH2_k127_7206206_1	1266925.JHVX01000005_gene1862	4.866e-89	298.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2VKR8@28216|Betaproteobacteria,371UP@32003|Nitrosomonadales	28216|Betaproteobacteria	M	Peptidase family M23	-	-	3.4.24.75	ko:K08259	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
CH2_k127_7215416_0	580332.Slit_1196	9.267e-217	685.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,2VJ54@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Belongs to the peptidase S16 family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_32,Lon_C
CH2_k127_7215416_1	396588.Tgr7_1071	6.552e-80	275.0	COG3396@1|root,COG3396@2|Bacteria,1NJ4Y@1224|Proteobacteria,1SGSK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	P-aminobenzoate N-oxygenase AurF	-	-	-	-	-	-	-	-	-	-	-	-	AurF
CH2_k127_7215416_2	1116472.MGMO_64c00080	2.868e-05	47.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	VIT,VWA
CH2_k127_7247964_2	1123393.KB891328_gene611	4.079e-183	575.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,2VKSY@28216|Betaproteobacteria,1KSF4@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	1.8.5.6	ko:K21307	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R11487	RC00168	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CH2_k127_7247964_9	1163617.SCD_n00140	1.177e-86	291.0	COG0607@1|root,COG0640@1|root,COG0607@2|Bacteria,COG0640@2|Bacteria,1R71B@1224|Proteobacteria,2VI9S@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5,Rhodanese
CH2_k127_7247964_7	1163617.SCD_n01899	2.566e-133	432.0	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,2VHEP@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
CH2_k127_7247964_0	583345.Mmol_0841	2.031e-243	764.0	COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,2VIBW@28216|Betaproteobacteria,2KKUB@206350|Nitrosomonadales	206350|Nitrosomonadales	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
CH2_k127_7247964_4	1163617.SCD_n01904	1.539e-173	557.0	COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,2VHXN@28216|Betaproteobacteria	28216|Betaproteobacteria	M	N-Acetylmuramoyl-L-alanine amidase	amiC	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
CH2_k127_7247964_11	1163617.SCD_n01905	3.259e-66	229.0	COG0802@1|root,COG0802@2|Bacteria,1RGYU@1224|Proteobacteria,2VSJY@28216|Betaproteobacteria	28216|Betaproteobacteria	S	atpase or kinase	yjeE	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
CH2_k127_7247964_5	265072.Mfla_1379	1.344e-159	511.0	COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,2VI7V@28216|Betaproteobacteria,2KM7D@206350|Nitrosomonadales	206350|Nitrosomonadales	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
CH2_k127_7247964_6	1163617.SCD_n01908	1.237e-143	458.0	COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,2VQ46@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
CH2_k127_7247964_12	1232683.ADIMK_1994	3.961e-46	175.0	COG0664@1|root,COG0664@2|Bacteria,1R6BV@1224|Proteobacteria,1S69P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	crp fnr family	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CH2_k127_7247964_1	472759.Nhal_1481	3.698e-206	649.0	COG2403@1|root,COG2403@2|Bacteria,1MV4C@1224|Proteobacteria	1224|Proteobacteria	S	cyclic 2,3-diphosphoglycerate synthetase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_7247964_3	1163617.SCD_n00219	3.97e-176	574.0	COG2199@1|root,COG2202@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2VNJ7@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase (GGDEF) domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS,PAS_9,dCache_1
CH2_k127_7247964_10	580332.Slit_1319	2.689e-74	252.0	COG1671@1|root,COG1671@2|Bacteria,1RCZA@1224|Proteobacteria,2VRAZ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Belongs to the UPF0178 family	yaiI	-	-	ko:K09768	-	-	-	-	ko00000	-	-	-	DUF188
CH2_k127_7247964_16	1118054.CAGW01000062_gene2238	3.283e-09	65.0	COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,4HGZI@91061|Bacilli,26R64@186822|Paenibacillaceae	91061|Bacilli	G	Phosphoglycerate kinase	yhfR	-	5.4.2.12	ko:K15634,ko:K15640	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
CH2_k127_7247964_8	395494.Galf_1854	4.071e-102	341.0	COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,2WFRY@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH
CH2_k127_7247964_14	1408164.MOLA814_00644	1.822e-29	119.0	COG5007@1|root,COG5007@2|Bacteria,1MZCZ@1224|Proteobacteria,2VU0K@28216|Betaproteobacteria,1KR5K@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	K	BolA-like protein	yrbA	-	-	-	-	-	-	-	-	-	-	-	BolA
CH2_k127_7247964_13	1163617.SCD_n00583	1.402e-44	163.0	COG0278@1|root,COG0278@2|Bacteria,1MZ4V@1224|Proteobacteria,2VSCX@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Belongs to the glutaredoxin family. Monothiol subfamily	grxD	-	-	ko:K07390	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Glutaredoxin
CH2_k127_7247964_15	1123392.AQWL01000002_gene1843	8.221e-21	93.0	2AG08@1|root,31649@2|Bacteria,1PWTZ@1224|Proteobacteria,2WCCN@28216|Betaproteobacteria,1KTFC@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_7266384_0	666681.M301_1373	1.164e-280	880.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,2VHSK@28216|Betaproteobacteria,2KMDN@206350|Nitrosomonadales	206350|Nitrosomonadales	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
CH2_k127_7266384_1	1123368.AUIS01000004_gene120	1.984e-80	285.0	COG2202@1|root,COG3829@1|root,COG4251@1|root,COG2202@2|Bacteria,COG3829@2|Bacteria,COG4251@2|Bacteria,1NWNJ@1224|Proteobacteria,1T2K7@1236|Gammaproteobacteria,2NDJ6@225057|Acidithiobacillales	1236|Gammaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Phosphonate-bd
CH2_k127_7266384_2	1348657.M622_08085	2.13e-35	139.0	COG0784@1|root,COG0784@2|Bacteria,1QUN7@1224|Proteobacteria,2WGQ0@28216|Betaproteobacteria,2KWBX@206389|Rhodocyclales	206389|Rhodocyclales	T	response regulator	-	-	-	ko:K02485	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg
CH2_k127_7266384_4	292415.Tbd_1330	6.275e-32	128.0	2AFZU@1|root,3163U@2|Bacteria,1PWT1@1224|Proteobacteria,2WCBW@28216|Betaproteobacteria,1KTE3@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_7266384_3	1123392.AQWL01000008_gene1144	2.822e-34	134.0	COG1538@1|root,COG1538@2|Bacteria,1RDVP@1224|Proteobacteria	1224|Proteobacteria	MU	Outer membrane efflux protein	-	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
CH2_k127_726947_2	1163617.SCD_n01964	2.059e-83	279.0	COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,2VJ1F@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	hemN	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
CH2_k127_726947_4	1163617.SCD_n00498	1.108e-35	141.0	COG1699@1|root,COG1699@2|Bacteria,1N9E7@1224|Proteobacteria,2VUC5@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum	fliW	-	-	ko:K13626	-	-	-	-	ko00000,ko02035	-	-	-	FliW
CH2_k127_726947_1	1123393.KB891317_gene2316	3.839e-113	370.0	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,2VH6I@28216|Betaproteobacteria,1KREX@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
CH2_k127_726947_0	1163617.SCD_n01844	1.655e-137	445.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,2VIFF@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
CH2_k127_726947_3	1120999.JONM01000019_gene3425	6.219e-74	254.0	COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,2VKD4@28216|Betaproteobacteria,2KPKE@206351|Neisseriales	206351|Neisseriales	S	Belongs to the multicopper oxidase YfiH RL5 family	yfiH	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
CH2_k127_7300367_0	1163617.SCD_n00901	3.023e-152	482.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,2VHEH@28216|Betaproteobacteria	28216|Betaproteobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
CH2_k127_7300367_1	269796.Rru_A2763	3.439e-125	425.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2UP6H@28211|Alphaproteobacteria,2JRF2@204441|Rhodospirillales	204441|Rhodospirillales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
CH2_k127_7300367_2	1123368.AUIS01000044_gene16	5.554e-58	211.0	COG3762@1|root,COG3762@2|Bacteria,1R61N@1224|Proteobacteria,1S7ZP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	membrane	Z012_08985	-	-	-	-	-	-	-	-	-	-	-	TPM_phosphatase
CH2_k127_7325679_1	1163617.SCD_n00213	1.149e-93	316.0	COG0810@1|root,COG0810@2|Bacteria,1MUMT@1224|Proteobacteria,2VKSW@28216|Betaproteobacteria	28216|Betaproteobacteria	M	TIGRFAM TonB family protein	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_2,TonB_C
CH2_k127_7325679_0	1485544.JQKP01000005_gene288	3.637e-246	773.0	COG0557@1|root,COG0557@2|Bacteria,1NGSQ@1224|Proteobacteria,2VHMM@28216|Betaproteobacteria,44VP2@713636|Nitrosomonadales	28216|Betaproteobacteria	K	RNB	rnb	-	3.1.13.1	ko:K01147	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNB
CH2_k127_7330767_4	1163617.SCD_n01408	1.279e-53	190.0	COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,2VHY7@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	-	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
CH2_k127_7330767_2	1163617.SCD_n01407	1.626e-106	349.0	COG1381@1|root,COG1381@2|Bacteria,1RHIC@1224|Proteobacteria,2VJUC@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
CH2_k127_7330767_0	1163617.SCD_n01400	1.422e-132	429.0	COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,2VHYP@28216|Betaproteobacteria	28216|Betaproteobacteria	M	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
CH2_k127_7330767_3	1163617.SCD_n01399	5.61e-84	284.0	COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,2VI4M@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
CH2_k127_7330767_5	395494.Galf_1191	2.802e-21	98.0	29X95@1|root,30IYK@2|Bacteria,1Q9AG@1224|Proteobacteria,2WCGR@28216|Betaproteobacteria,44W1V@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Domain of unknown function (DUF4845)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4845
CH2_k127_7330767_1	1163617.SCD_n01397	8.451e-128	412.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,2VJ9D@28216|Betaproteobacteria	28216|Betaproteobacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
CH2_k127_7490462_1	580332.Slit_1673	7.305e-65	226.0	COG1670@1|root,COG1670@2|Bacteria,1RB1I@1224|Proteobacteria,2VS72@28216|Betaproteobacteria,44WC6@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Domain of unknown function (DUF4202)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4202
CH2_k127_7490462_0	1163617.SCD_n02166	1.561e-122	400.0	COG0583@1|root,COG0583@2|Bacteria,1MVA1@1224|Proteobacteria,2VIBJ@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Transcriptional regulator	oxyR	-	-	ko:K04761	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
CH2_k127_7490462_2	713586.KB900536_gene1460	1.941e-11	66.0	COG1592@1|root,COG1592@2|Bacteria,1R9WG@1224|Proteobacteria,1S25G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	PFAM Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
CH2_k127_7493643_8	1163617.SCD_n00077	6.007e-17	81.0	COG0526@1|root,COG0526@2|Bacteria,1RDGI@1224|Proteobacteria,2VT2S@28216|Betaproteobacteria	28216|Betaproteobacteria	CO	Redoxin domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CH2_k127_7493643_6	1123368.AUIS01000005_gene398	1.25e-30	128.0	COG2318@1|root,COG2318@2|Bacteria,1RD3M@1224|Proteobacteria,1S5RX@1236|Gammaproteobacteria,2NE49@225057|Acidithiobacillales	225057|Acidithiobacillales	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
CH2_k127_7493643_1	1123392.AQWL01000005_gene3176	2.961e-54	196.0	COG0526@1|root,COG0526@2|Bacteria,1RDGI@1224|Proteobacteria,2VT2S@28216|Betaproteobacteria,1KRYX@119069|Hydrogenophilales	119069|Hydrogenophilales	CO	SCO1/SenC	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_7493643_2	1163617.SCD_n00278	2.132e-52	188.0	COG1238@1|root,COG1238@2|Bacteria,1RHUV@1224|Proteobacteria,2VUM5@28216|Betaproteobacteria	28216|Betaproteobacteria	S	membrane	yqaA	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
CH2_k127_7493643_4	232721.Ajs_0946	9.291e-33	128.0	COG2944@1|root,COG2944@2|Bacteria,1MZGM@1224|Proteobacteria,2VSV0@28216|Betaproteobacteria,4AJJH@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM helix-turn-helix domain protein	-	-	-	ko:K07726	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3,HTH_31
CH2_k127_7493643_3	395495.Lcho_3171	1.72e-47	172.0	COG4737@1|root,COG4737@2|Bacteria,1N7N5@1224|Proteobacteria,2VTY4@28216|Betaproteobacteria,1KMHP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Cytotoxic translational repressor of toxin-antitoxin stability system	-	-	-	-	-	-	-	-	-	-	-	-	RelE
CH2_k127_7493643_7	322710.Avin_40590	7.367e-20	91.0	COG3636@1|root,COG3636@2|Bacteria,1N75D@1224|Proteobacteria,1SC8G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	addiction module antidote protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
CH2_k127_7493643_5	1163617.SCD_n00048	3.597e-31	133.0	COG5473@1|root,COG5473@2|Bacteria,1N9UJ@1224|Proteobacteria,2VNM5@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_7493643_0	1163617.SCD_n00047	2.847e-64	222.0	COG2334@1|root,COG2334@2|Bacteria,1MUKJ@1224|Proteobacteria,2VH2I@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Belongs to the pseudomonas-type ThrB family	thrB	-	2.7.1.39	ko:K02204	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	APH
CH2_k127_7613827_3	1163617.SCD_n01801	1.572e-39	149.0	COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,2VI86@28216|Betaproteobacteria	28216|Betaproteobacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
CH2_k127_7613827_0	1163617.SCD_n01800	5.668e-180	573.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,2VIG2@28216|Betaproteobacteria	28216|Betaproteobacteria	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7,HflK_N
CH2_k127_7613827_1	1163617.SCD_n01799	1.803e-143	459.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,2VI9W@28216|Betaproteobacteria	28216|Betaproteobacteria	O	HflC and HflK could regulate a protease	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
CH2_k127_7613827_4	1163617.SCD_n01798	1.292e-22	98.0	COG3242@1|root,COG3242@2|Bacteria,1NG9Q@1224|Proteobacteria,2VXNJ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09937	-	-	-	-	ko00000	-	-	-	DUF2065
CH2_k127_7613827_2	582744.Msip34_1687	3.896e-83	279.0	COG3705@1|root,COG3705@2|Bacteria,1MWIG@1224|Proteobacteria,2VHVX@28216|Betaproteobacteria,2KKH5@206350|Nitrosomonadales	206350|Nitrosomonadales	E	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine	hisZ	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
CH2_k127_7650454_2	1121921.KB898708_gene1523	2.775e-22	96.0	2EQCX@1|root,33HYZ@2|Bacteria,1NGQU@1224|Proteobacteria,1SJBT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_7650454_1	1163617.SCD_n02027	1.345e-91	302.0	COG3260@1|root,COG3260@2|Bacteria,1QUBE@1224|Proteobacteria,2VP8A@28216|Betaproteobacteria	28216|Betaproteobacteria	C	NADH ubiquinone oxidoreductase 20 kDa subunit	hyfI	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q6
CH2_k127_7650454_0	1163617.SCD_n02026	1.636e-247	770.0	COG3261@1|root,COG3262@1|root,COG3261@2|Bacteria,COG3262@2|Bacteria,1QUBF@1224|Proteobacteria,2VJ0R@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Respiratory-chain NADH dehydrogenase, 49 Kd subunit	hyfG	-	-	-	-	-	-	-	-	-	-	-	Complex1_30kDa,Complex1_49kDa,NiFeSe_Hases
CH2_k127_7671495_5	556269.ACDQ01000006_gene1578	1.187e-08	58.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2VM3A@28216|Betaproteobacteria,472KU@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Sel1-like repeats.	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
CH2_k127_7671495_1	395494.Galf_1765	3.927e-93	320.0	COG4235@1|root,COG4235@2|Bacteria,1MY4J@1224|Proteobacteria,2VQ05@28216|Betaproteobacteria,44V8W@713636|Nitrosomonadales	28216|Betaproteobacteria	O	TIGRFAM cytochrome c-type biogenesis protein CcmI	cycH	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	TPR_16,TPR_2
CH2_k127_7671495_3	323848.Nmul_A1207	8.273e-42	158.0	COG3088@1|root,COG3088@2|Bacteria,1MZZ5@1224|Proteobacteria,2VU7C@28216|Betaproteobacteria,37311@32003|Nitrosomonadales	28216|Betaproteobacteria	P	subunit of a heme lyase	ccmH	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH
CH2_k127_7671495_2	1538295.JY96_13775	4.763e-78	264.0	COG0526@1|root,COG0526@2|Bacteria,1RI3N@1224|Proteobacteria,2VR8D@28216|Betaproteobacteria,1KKN4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	CO	Periplasmic protein thiol	dsbE	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,Redoxin
CH2_k127_7671495_0	1266925.JHVX01000001_gene2488	3.91e-293	912.0	COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,2VHUE@28216|Betaproteobacteria,3725U@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Cytochrome c-type biogenesis protein CcmF	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
CH2_k127_7671495_4	323848.Nmul_A1210	3.632e-20	90.0	COG2332@1|root,COG2332@2|Bacteria,1RHN5@1224|Proteobacteria,2VRKZ@28216|Betaproteobacteria,3731F@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	ccmE	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
CH2_k127_7706592_3	1163617.SCD_n01616	1.026e-21	95.0	COG1639@1|root,COG1639@2|Bacteria,1NJC4@1224|Proteobacteria,2VHRZ@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Metal-dependent hydrolase HDOD	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
CH2_k127_7706592_0	1163617.SCD_n01615	7.529e-115	378.0	COG0438@1|root,COG0438@2|Bacteria,1RB3J@1224|Proteobacteria,2VJNY@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
CH2_k127_7706592_1	1266914.ATUK01000010_gene1174	6.301e-41	163.0	COG1357@1|root,COG1357@2|Bacteria,1N15C@1224|Proteobacteria,1S9A9@1236|Gammaproteobacteria,1X1IB@135613|Chromatiales	135613|Chromatiales	S	Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
CH2_k127_7706592_2	580332.Slit_1623	3.44e-23	102.0	COG0566@1|root,COG0566@2|Bacteria,1R9JA@1224|Proteobacteria,2VQDG@28216|Betaproteobacteria,44VNV@713636|Nitrosomonadales	28216|Betaproteobacteria	J	SpoU rRNA Methylase family	spoU	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase
CH2_k127_7772052_1	1163617.SCD_n02948	1.073e-105	346.0	COG0232@1|root,COG0232@2|Bacteria,1MVQ2@1224|Proteobacteria,2VI7B@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Belongs to the dGTPase family. Type 2 subfamily	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
CH2_k127_7772052_0	1123393.KB891332_gene2829	3.783e-117	381.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,2VHUY@28216|Betaproteobacteria,1KRA6@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Conserved region in glutamate synthase	-	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
CH2_k127_7869312_1	998674.ATTE01000001_gene2098	2.78e-19	89.0	COG4226@1|root,COG4226@2|Bacteria,1N9EG@1224|Proteobacteria,1SCXG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	HicB family	-	-	-	-	-	-	-	-	-	-	-	-	HicB
CH2_k127_7869312_0	1163617.SCD_n01876	2.273e-215	675.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,2VH51@28216|Betaproteobacteria	28216|Betaproteobacteria	O	peptidase, U32	yhbU_1	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
CH2_k127_7871380_5	76114.ebA4676	1.919e-49	179.0	COG0176@1|root,COG0176@2|Bacteria,1MWQ8@1224|Proteobacteria,2VHIN@28216|Betaproteobacteria,2KV4P@206389|Rhodocyclales	206389|Rhodocyclales	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
CH2_k127_7871380_1	1123368.AUIS01000007_gene2814	6.977e-158	506.0	COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,1T1JB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
CH2_k127_7871380_3	292415.Tbd_2015	1.134e-97	321.0	COG4657@1|root,COG4657@2|Bacteria,1MU8X@1224|Proteobacteria,2VH0C@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
CH2_k127_7871380_4	497321.C664_14194	5.998e-90	298.0	COG2878@1|root,COG2878@2|Bacteria,1MUWU@1224|Proteobacteria,2VN5I@28216|Betaproteobacteria,2KVNK@206389|Rhodocyclales	206389|Rhodocyclales	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4_21
CH2_k127_7871380_0	1123392.AQWL01000001_gene1457	8.794e-220	695.0	COG4656@1|root,COG4656@2|Bacteria,1PJVF@1224|Proteobacteria,2VM4P@28216|Betaproteobacteria,1KSZA@119069|Hydrogenophilales	119069|Hydrogenophilales	C	RnfC Barrel sandwich hybrid domain	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_51K,RnfC_N,SLBB
CH2_k127_7871380_2	1163617.SCD_n01981	2.473e-144	464.0	COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,2VJZJ@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Part of a membrane complex involved in electron transport	rnfD	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
CH2_k127_7871380_6	580332.Slit_2395	2.531e-49	180.0	COG4659@1|root,COG4659@2|Bacteria,1RDEP@1224|Proteobacteria,2VS39@28216|Betaproteobacteria,44VR1@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
CH2_k127_7874072_0	640081.Dsui_2420	4.322e-197	621.0	COG1032@1|root,COG1032@2|Bacteria,1MUG3@1224|Proteobacteria,2VJ9A@28216|Betaproteobacteria,2KV3Z@206389|Rhodocyclales	206389|Rhodocyclales	C	UPF0313 protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
CH2_k127_7874072_3	1163617.SCD_n01991	1.311e-17	83.0	28PU4@1|root,2ZCF6@2|Bacteria,1RBK2@1224|Proteobacteria,2VQ65@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_7874072_1	1288494.EBAPG3_12820	3.159e-65	228.0	COG4133@1|root,COG4133@2|Bacteria,1MZPC@1224|Proteobacteria,2VMGA@28216|Betaproteobacteria,372UK@32003|Nitrosomonadales	28216|Betaproteobacteria	P	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system	ccmA	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
CH2_k127_7874072_2	228410.NE0765	9.273e-49	180.0	COG2386@1|root,COG2386@2|Bacteria,1NJB0@1224|Proteobacteria,2VNPU@28216|Betaproteobacteria,371Q1@32003|Nitrosomonadales	28216|Betaproteobacteria	U	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmB	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
CH2_k127_7889100_0	1163617.SCD_n00338	1.197e-184	583.0	COG1168@1|root,COG1168@2|Bacteria,1MY33@1224|Proteobacteria,2VHZ6@28216|Betaproteobacteria	28216|Betaproteobacteria	E	PFAM aminotransferase class I and II	-	-	4.4.1.8	ko:K00842,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CH2_k127_7889100_3	1163617.SCD_n02417	3.199e-56	202.0	COG1664@1|root,COG1664@2|Bacteria,1N26P@1224|Proteobacteria,2VSIS@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Integral membrane protein CcmA involved in cell shape determination	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
CH2_k127_7889100_1	1163617.SCD_n01360	8.323e-75	256.0	COG4681@1|root,COG4681@2|Bacteria,1RDR9@1224|Proteobacteria,2VR81@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM YaeQ family protein	yaeQ	-	-	-	-	-	-	-	-	-	-	-	YaeQ
CH2_k127_7889100_2	1538295.JY96_09755	3.579e-62	232.0	28KDG@1|root,2Z9ZZ@2|Bacteria,1R86C@1224|Proteobacteria,2W193@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_7915467_2	1163617.SCD_n01616	8.741e-158	512.0	COG1639@1|root,COG1639@2|Bacteria,1NJC4@1224|Proteobacteria,2VHRZ@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Metal-dependent hydrolase HDOD	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
CH2_k127_7915467_8	1485544.JQKP01000018_gene585	4.798e-76	263.0	COG0220@1|root,COG0220@2|Bacteria,1RIVI@1224|Proteobacteria,2WGXS@28216|Betaproteobacteria,44VC8@713636|Nitrosomonadales	28216|Betaproteobacteria	J	tRNA (guanine-N7-)-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_7915467_6	1163617.SCD_n01618	1.478e-123	406.0	COG1360@1|root,COG1360@2|Bacteria,1MW1Y@1224|Proteobacteria,2VHMJ@28216|Betaproteobacteria	28216|Betaproteobacteria	N	PFAM OmpA MotB domain protein	motB	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
CH2_k127_7915467_3	1123392.AQWL01000003_gene205	2.072e-144	461.0	COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,2VHPX@28216|Betaproteobacteria,1KRF1@119069|Hydrogenophilales	119069|Hydrogenophilales	N	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
CH2_k127_7915467_9	1163617.SCD_n01621	2.049e-74	255.0	COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,2VQ06@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
CH2_k127_7915467_1	1163617.SCD_n01622	2.936e-164	526.0	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,2VIBP@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
CH2_k127_7915467_5	1163617.SCD_n01623	2.486e-128	413.0	COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,2VHDG@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
CH2_k127_7915467_7	1163617.SCD_n01624	9.139e-82	278.0	COG0764@1|root,COG0764@2|Bacteria,1RH2T@1224|Proteobacteria,2VRKQ@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
CH2_k127_7915467_4	1163617.SCD_n01625	8.802e-134	434.0	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,2VHJR@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
CH2_k127_7915467_10	1163617.SCD_n01626	1.125e-63	223.0	COG2825@1|root,COG2825@2|Bacteria,1RD8X@1224|Proteobacteria,2VRZI@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Belongs to the skp family	ompH	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
CH2_k127_7915467_0	1163617.SCD_n01627	0.0	1149.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,2VHTX@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
CH2_k127_7915467_11	1163617.SCD_n01628	1.25e-59	208.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,2VHBW@28216|Betaproteobacteria	28216|Betaproteobacteria	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
CH2_k127_7951944_4	1003200.AXXA_28150	7.473e-12	67.0	2EJ6A@1|root,33CXH@2|Bacteria,1NPSZ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_7951944_6	1045856.EcWSU1_01650	8.878e-06	51.0	2CFXH@1|root,32S2R@2|Bacteria,1MZNE@1224|Proteobacteria,1S8Z0@1236|Gammaproteobacteria,3X2PG@547|Enterobacter	1236|Gammaproteobacteria	S	BssS protein family	bssS	GO:0008150,GO:0043900,GO:0050789,GO:0050794,GO:0065007,GO:1900190	-	ko:K12148	-	-	-	-	ko00000,ko02048	-	-	-	BssS
CH2_k127_7951944_1	1027273.GZ77_09040	1.147e-19	90.0	2E00C@1|root,32VPT@2|Bacteria,1N0XY@1224|Proteobacteria,1SA3H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,YdaS_antitoxin
CH2_k127_7951944_2	1283300.ATXB01000002_gene2803	9.679e-17	86.0	COG2932@1|root,COG2932@2|Bacteria,1QER0@1224|Proteobacteria,1SEJU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Peptidase S24-like	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,Peptidase_S24
CH2_k127_7951944_5	1235457.C404_22860	1.509e-07	57.0	COG1396@1|root,COG1396@2|Bacteria,1P08F@1224|Proteobacteria,2W75Q@28216|Betaproteobacteria,1KDW8@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
CH2_k127_7957137_11	1122236.KB905146_gene1923	3.503e-24	102.0	COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,2VI7I@28216|Betaproteobacteria,2KKDP@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
CH2_k127_7957137_6	1163617.SCD_n02482	5.327e-127	412.0	COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,2VHIW@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
CH2_k127_7957137_8	1163617.SCD_n02481	1.547e-92	312.0	COG1589@1|root,COG1589@2|Bacteria,1N0T7@1224|Proteobacteria,2VRMV@28216|Betaproteobacteria	28216|Betaproteobacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
CH2_k127_7957137_0	1163617.SCD_n02480	9.626e-231	718.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,2VGZP@28216|Betaproteobacteria	28216|Betaproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
CH2_k127_7957137_2	1288494.EBAPG3_28120	2.386e-186	589.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,2VH0S@28216|Betaproteobacteria,372PE@32003|Nitrosomonadales	28216|Betaproteobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
CH2_k127_7957137_4	1163617.SCD_n02478	4.663e-144	463.0	COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,2VHI8@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108	ko:K02535	ko00540,ko01100,map00540,map01100	M00060	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxC
CH2_k127_7957137_12	395494.Galf_0342	7.89e-08	55.0	2AG2M@1|root,3166Z@2|Bacteria,1PWZE@1224|Proteobacteria,2WCHD@28216|Betaproteobacteria,44W3K@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_7957137_5	522306.CAP2UW1_0231	3.805e-141	460.0	28HWK@1|root,2Z82H@2|Bacteria,1MVDT@1224|Proteobacteria,2VM8W@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF1615)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1615
CH2_k127_7957137_7	522306.CAP2UW1_2377	3.757e-122	397.0	COG2961@1|root,COG2961@2|Bacteria,1MWGA@1224|Proteobacteria,2VHM4@28216|Betaproteobacteria,1KQP1@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	J	Specifically methylates the adenine in position 2030 of 23S rRNA	rlmJ	-	2.1.1.266	ko:K07115	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RsmJ
CH2_k127_7957137_10	292415.Tbd_2154	8.391e-31	126.0	COG5626@1|root,COG5626@2|Bacteria,1N8QB@1224|Proteobacteria,2VWJM@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF2288)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2288
CH2_k127_7957137_1	1163617.SCD_n00468	3.311e-207	650.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,2VHNC@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
CH2_k127_7957137_3	1163617.SCD_n00467	4.292e-176	558.0	COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,2VJKV@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
CH2_k127_7957137_9	1163617.SCD_n00466	1.158e-91	309.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,2VP72@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
CH2_k127_7963258_4	1485544.JQKP01000001_gene1269	2.088e-97	322.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2VJDZ@28216|Betaproteobacteria,44VGP@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	arnB	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
CH2_k127_7963258_7	1163617.SCD_n01750	1.778e-58	205.0	COG2076@1|root,COG2076@2|Bacteria,1NAUF@1224|Proteobacteria,2WE9Q@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Small Multidrug Resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	EamA,Multi_Drug_Res
CH2_k127_7963258_1	1163617.SCD_n01749	7.961e-223	703.0	COG1807@1|root,COG1807@2|Bacteria,1NMIZ@1224|Proteobacteria,2VMHK@28216|Betaproteobacteria	28216|Betaproteobacteria	M	PFAM glycosyl transferase family 39	arnT	-	-	-	-	-	-	-	-	-	-	-	PMT,PMT_2
CH2_k127_7963258_6	292415.Tbd_1000	4.056e-61	216.0	COG2840@1|root,COG2840@2|Bacteria,1RH34@1224|Proteobacteria,2VQ2S@28216|Betaproteobacteria,1KTBK@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Small MutS-related domain	-	-	-	-	-	-	-	-	-	-	-	-	Smr
CH2_k127_7963258_3	1163617.SCD_n01743	1.158e-182	574.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,2VIVV@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
CH2_k127_7963258_0	1288494.EBAPG3_6760	0.0	1035.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,2VHJV@28216|Betaproteobacteria,372D7@32003|Nitrosomonadales	28216|Betaproteobacteria	D	PFAM cell divisionFtsK SpoIIIE	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
CH2_k127_7963258_5	1163617.SCD_n01183	9.69e-77	263.0	COG2834@1|root,COG2834@2|Bacteria,1PXDV@1224|Proteobacteria,2VNNH@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
CH2_k127_7963258_2	1163617.SCD_n01184	1.292e-222	696.0	COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,2VHN9@28216|Betaproteobacteria	28216|Betaproteobacteria	L	AAA ATPase central domain protein	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
CH2_k127_7963258_8	714943.Mucpa_3549	5.505e-37	143.0	COG4886@1|root,COG4886@2|Bacteria,4PJB4@976|Bacteroidetes,1IZXR@117747|Sphingobacteriia	976|Bacteroidetes	S	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_8034141_1	292415.Tbd_0551	2.98e-115	376.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VNYV@28216|Betaproteobacteria,1KS6P@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
CH2_k127_8034141_2	3988.XP_002536083.1	2.83e-91	307.0	COG1131@1|root,KOG0059@2759|Eukaryota	2759|Eukaryota	V	ATPase activity, coupled to transmembrane movement of substances	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
CH2_k127_8034141_3	261292.Nit79A3_3526	2.637e-77	263.0	COG0122@1|root,COG0122@2|Bacteria,1MX9C@1224|Proteobacteria,2VHMQ@28216|Betaproteobacteria,3731U@32003|Nitrosomonadales	28216|Betaproteobacteria	L	endonuclease III	alkA	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
CH2_k127_8034141_0	697282.Mettu_3162	2.289e-148	503.0	COG0642@1|root,COG2199@1|root,COG2202@1|root,COG3829@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,COG3829@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,Hpt,NMT1,PAS,PAS_3,PAS_4,PAS_9,Response_reg
CH2_k127_8043519_5	1123392.AQWL01000006_gene639	1.374e-70	241.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,1KSIU@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
CH2_k127_8043519_3	1268237.G114_05485	1.583e-92	306.0	COG0663@1|root,COG0663@2|Bacteria,1N26K@1224|Proteobacteria,1S06B@1236|Gammaproteobacteria,1Y52P@135624|Aeromonadales	135624|Aeromonadales	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
CH2_k127_8043519_0	1123392.AQWL01000006_gene643	0.0	1006.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,2VHKJ@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Sulfate transporter antisigma-factor antagonist STAS	-	-	-	-	-	-	-	-	-	-	-	-	STAS,Sulfate_transp
CH2_k127_8043519_1	1163617.SCD_n02017	9.732e-297	919.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,2VHKJ@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Sulfate transporter antisigma-factor antagonist STAS	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
CH2_k127_8043519_4	1163617.SCD_n02016	1.172e-83	288.0	COG4275@1|root,COG4275@2|Bacteria,1MYDE@1224|Proteobacteria,2VKAX@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Chromate resistance	chrB	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist
CH2_k127_8043519_2	1121004.ATVC01000026_gene191	1.723e-164	522.0	COG1840@1|root,COG1840@2|Bacteria,1MUEG@1224|Proteobacteria,2VHI6@28216|Betaproteobacteria,2KQP6@206351|Neisseriales	206351|Neisseriales	P	Bacterial extracellular solute-binding protein	fbpA	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_1,SBP_bac_6,SBP_bac_8
CH2_k127_8043519_6	287.DR97_2585	1.061e-21	98.0	COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,1RP55@1236|Gammaproteobacteria,1YDS1@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	fbpB	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
CH2_k127_8047359_3	580332.Slit_2395	1.241e-33	132.0	COG4659@1|root,COG4659@2|Bacteria,1RDEP@1224|Proteobacteria,2VS39@28216|Betaproteobacteria,44VR1@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
CH2_k127_8047359_2	1163617.SCD_n01983	4.197e-90	302.0	COG4660@1|root,COG4660@2|Bacteria,1MW6N@1224|Proteobacteria,2VNWT@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03613	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
CH2_k127_8047359_1	1163617.SCD_n01986	2.363e-102	336.0	COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,2VIRB@28216|Betaproteobacteria	28216|Betaproteobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
CH2_k127_8047359_0	1163617.SCD_n01987	1.206e-160	512.0	COG4398@1|root,COG4398@2|Bacteria,1RBRR@1224|Proteobacteria,2VQ7K@28216|Betaproteobacteria	28216|Betaproteobacteria	S	FIST_C	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
CH2_k127_8047359_4	323848.Nmul_A2703	3.4e-17	82.0	2AFCJ@1|root,315C6@2|Bacteria,1RH66@1224|Proteobacteria,2VSTN@28216|Betaproteobacteria,37352@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Domain of unknown function (DUF1841)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1841
CH2_k127_8084710_5	1163617.SCD_n00562	9.72e-17	80.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,2VI24@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Belongs to the SIS family. GutQ KpsF subfamily	kdsD	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
CH2_k127_8084710_2	1163617.SCD_n00561	6.868e-76	260.0	COG1778@1|root,COG1778@2|Bacteria,1RH85@1224|Proteobacteria,2VRQX@28216|Betaproteobacteria	28216|Betaproteobacteria	M	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family	kdsC	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase,Hydrolase_3
CH2_k127_8084710_4	522306.CAP2UW1_0639	5.725e-23	105.0	COG3117@1|root,COG3117@2|Bacteria,1R5UK@1224|Proteobacteria,2VU37@28216|Betaproteobacteria,1KR5G@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	Lipopolysaccharide-assembly, LptC-related	lptC	-	-	ko:K11719	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptC
CH2_k127_8084710_3	1163617.SCD_n00559	3.255e-75	257.0	COG1934@1|root,COG1934@2|Bacteria,1N776@1224|Proteobacteria,2VSI4@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane	lptA	-	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA
CH2_k127_8084710_0	1163617.SCD_n00558	2.672e-125	407.0	COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,2VH29@28216|Betaproteobacteria	28216|Betaproteobacteria	S	ABC transporter	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
CH2_k127_8084710_1	1163617.SCD_n00557	1.384e-109	364.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,2VIEV@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
CH2_k127_8097596_2	195250.CM001776_gene2187	3.051e-50	193.0	COG0457@1|root,COG2242@1|root,COG0457@2|Bacteria,COG2242@2|Bacteria,1G59A@1117|Cyanobacteria	1117|Cyanobacteria	H	TIGRFAM methyltransferase FkbM family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
CH2_k127_8097596_0	338969.Rfer_0630	8.653e-127	422.0	COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,2VJTA@28216|Betaproteobacteria,4ACM7@80864|Comamonadaceae	28216|Betaproteobacteria	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	fliC	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_IN,Flagellin_N
CH2_k127_8097596_3	1163617.SCD_n01649	7.215e-21	96.0	COG1334@1|root,COG1334@2|Bacteria	2|Bacteria	N	flagellar protein FlaG	flaG	-	-	ko:K06603	-	-	-	-	ko00000,ko02035	-	-	-	FlaG
CH2_k127_8097596_1	1288494.EBAPG3_20210	6.12e-98	330.0	COG1345@1|root,COG1345@2|Bacteria,1MUVP@1224|Proteobacteria,2VHMK@28216|Betaproteobacteria,371U5@32003|Nitrosomonadales	28216|Betaproteobacteria	N	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	fliD	-	-	ko:K02407	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_IN,FliD_C,FliD_N
CH2_k127_8125282_11	1132855.KB913035_gene286	1.546e-18	85.0	COG0810@1|root,COG0810@2|Bacteria,1MUMT@1224|Proteobacteria,2VKSW@28216|Betaproteobacteria,2KMED@206350|Nitrosomonadales	206350|Nitrosomonadales	M	TIGRFAM TonB family	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
CH2_k127_8125282_0	76114.ebA1517	7.176e-135	439.0	COG0438@1|root,COG0438@2|Bacteria,1MUYN@1224|Proteobacteria,2VNWP@28216|Betaproteobacteria,2KXWQ@206389|Rhodocyclales	206389|Rhodocyclales	M	Domain of unknown function (DUF1972)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1972,Glyco_trans_1_2
CH2_k127_8125282_8	1054213.HMPREF9946_00984	6.671e-29	128.0	COG0500@1|root,COG2226@2|Bacteria,1N73D@1224|Proteobacteria,2TS2J@28211|Alphaproteobacteria,2JWIF@204441|Rhodospirillales	204441|Rhodospirillales	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CH2_k127_8125282_7	879212.DespoDRAFT_01898	5.579e-31	134.0	COG0500@1|root,COG2226@2|Bacteria,1QYW6@1224|Proteobacteria,43DBX@68525|delta/epsilon subdivisions,2X8HY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_8125282_9	1120985.AUMI01000014_gene796	4.396e-25	118.0	COG0859@1|root,COG0859@2|Bacteria,1US67@1239|Firmicutes,4H281@909932|Negativicutes	909932|Negativicutes	M	heptosyltransferase	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
CH2_k127_8125282_4	1124780.ANNU01000028_gene955	1.007e-52	200.0	COG0438@1|root,COG0438@2|Bacteria,4NJ6W@976|Bacteroidetes,47N47@768503|Cytophagia	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
CH2_k127_8125282_6	861299.J421_1550	8.394e-43	175.0	COG3534@1|root,COG3534@2|Bacteria	2|Bacteria	G	alpha-L-arabinofuranosidase	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C,Glyco_hydro_79n
CH2_k127_8125282_15	1297742.A176_07616	0.000207	54.0	COG2244@1|root,COG2244@2|Bacteria,1NI6U@1224|Proteobacteria,42VHT@68525|delta/epsilon subdivisions,2WRIK@28221|Deltaproteobacteria,2YYUI@29|Myxococcales	28221|Deltaproteobacteria	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
CH2_k127_8125282_13	754476.Q7A_1434	5.931e-14	80.0	COG1045@1|root,COG1045@2|Bacteria,1RHGV@1224|Proteobacteria	1224|Proteobacteria	E	serine acetyltransferase	-	-	2.3.1.30	ko:K00640,ko:K03819	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2
CH2_k127_8125282_12	1499686.BN1079_02238	4.787e-18	96.0	COG1596@1|root,COG1596@2|Bacteria,1PK0U@1224|Proteobacteria,1SCUF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export
CH2_k127_8125282_16	652103.Rpdx1_4770	0.0006485	52.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1R5P9@1224|Proteobacteria,2U0GE@28211|Alphaproteobacteria,3JS2C@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	DM	protein involved in exopolysaccharide biosynthesis	-	-	-	ko:K16554	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	8.A.3.1	-	-	AAA_31,GNVR,Wzz
CH2_k127_8125282_14	1260356.D920_00574	2.154e-10	70.0	COG0489@1|root,COG0489@2|Bacteria,1TS4R@1239|Firmicutes,4HCEN@91061|Bacilli,4AZIZ@81852|Enterococcaceae	91061|Bacilli	D	Psort location CytoplasmicMembrane, score	ywqD	-	-	-	-	-	-	-	-	-	-	-	AAA_31,ParA
CH2_k127_8125282_10	172088.AUGA01000005_gene7860	5.081e-25	115.0	COG2227@1|root,COG2227@2|Bacteria,1R5ZG@1224|Proteobacteria,2TZ3A@28211|Alphaproteobacteria,3JVYA@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	H	Methyltransferase domain	MA20_06080	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_12,Methyltransf_23
CH2_k127_8125282_2	1163617.SCD_n00212	5.569e-82	277.0	COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,2VJQA@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Belongs to the UPF0301 (AlgH) family	algH	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
CH2_k127_8125282_5	1163617.SCD_n00211	1.472e-50	184.0	COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,2VUH0@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	yqgF	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
CH2_k127_8125282_3	1288494.EBAPG3_28000	6.325e-61	216.0	COG2065@1|root,COG2065@2|Bacteria,1RI6U@1224|Proteobacteria,2VSNM@28216|Betaproteobacteria,3733Q@32003|Nitrosomonadales	28216|Betaproteobacteria	F	Phosphoribosyl transferase domain	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
CH2_k127_8125282_1	1288494.EBAPG3_28010	1.152e-86	288.0	COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,2VHG9@28216|Betaproteobacteria,372F3@32003|Nitrosomonadales	28216|Betaproteobacteria	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
CH2_k127_8167656_0	395493.BegalDRAFT_3559	9.506e-312	968.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,1RP3T@1236|Gammaproteobacteria,45ZUZ@72273|Thiotrichales	72273|Thiotrichales	G	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
CH2_k127_8167656_3	765913.ThidrDRAFT_2786	3.75e-19	102.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WVV9@135613|Chromatiales	135613|Chromatiales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_9
CH2_k127_8167656_1	1157490.EL26_19350	2.852e-153	513.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,4HA3G@91061|Bacilli,2798R@186823|Alicyclobacillaceae	91061|Bacilli	T	Putative diguanylate phosphodiesterase	-	-	2.7.7.65	ko:K21023	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000	-	-	-	EAL,GGDEF,HAMP,MHYT,PAS,PAS_3,PAS_4,PAS_9
CH2_k127_8167656_4	234267.Acid_5597	7.241e-14	83.0	2FIKE@1|root,34ACF@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_8167656_2	1163617.SCD_n00792	1.06e-121	400.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,2VHQS@28216|Betaproteobacteria	28216|Betaproteobacteria	K	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	ko:K06714	-	-	-	-	ko00000,ko03000	-	-	-	HTH_8,PAS_4,Sigma54_activat
CH2_k127_8207110_1	582744.Msip34_0586	5.814e-195	614.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,2VHPE@28216|Betaproteobacteria,2KKCS@206350|Nitrosomonadales	206350|Nitrosomonadales	NU	PFAM type II secretion system	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
CH2_k127_8207110_0	748247.AZKH_3571	3.322e-251	786.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria,2KUK3@206389|Rhodocyclales	206389|Rhodocyclales	NU	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	pilB	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
CH2_k127_8207110_2	1163617.SCD_n00412	1.447e-158	508.0	COG1565@1|root,COG1565@2|Bacteria,1N3CJ@1224|Proteobacteria,2VHBE@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
CH2_k127_8207110_3	265072.Mfla_0229	4.05e-45	168.0	COG1028@1|root,COG1028@2|Bacteria,1MUUV@1224|Proteobacteria,2VK0U@28216|Betaproteobacteria,2KKSM@206350|Nitrosomonadales	206350|Nitrosomonadales	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	1.5.1.33	ko:K03793	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
CH2_k127_8247336_0	338969.Rfer_0744	1.948e-120	396.0	COG3658@1|root,COG3658@2|Bacteria,1RB03@1224|Proteobacteria,2VQQ7@28216|Betaproteobacteria,4AJE0@80864|Comamonadaceae	28216|Betaproteobacteria	C	Cytochrome b/b6/petB	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
CH2_k127_8247336_4	1123368.AUIS01000019_gene1208	5.303e-64	223.0	COG3658@1|root,COG3658@2|Bacteria,1N28F@1224|Proteobacteria,1S2S2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	PFAM Di-haem cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	DHC
CH2_k127_8247336_6	1123368.AUIS01000019_gene1209	1.714e-35	142.0	COG1858@1|root,COG1858@2|Bacteria,1QVT1@1224|Proteobacteria,1T4IH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Domain of unknown function (DUF1924)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1924
CH2_k127_8247336_2	1163617.SCD_n00285	9.557e-81	278.0	COG4395@1|root,COG4395@2|Bacteria,1NSUG@1224|Proteobacteria,2VNS7@28216|Betaproteobacteria	28216|Betaproteobacteria	S	import inner membrane translocase, subunit Tim44	-	-	-	-	-	-	-	-	-	-	-	-	Tim44
CH2_k127_8247336_5	153948.NAL212_2620	2.485e-38	145.0	COG2924@1|root,COG2924@2|Bacteria,1MZ2V@1224|Proteobacteria,2VTYU@28216|Betaproteobacteria,373IU@32003|Nitrosomonadales	28216|Betaproteobacteria	C	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes	yggX	-	-	-	-	-	-	-	-	-	-	-	Iron_traffic
CH2_k127_8247336_1	1123393.KB891332_gene2752	2.347e-107	352.0	COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,2VI2C@28216|Betaproteobacteria,1KRQG@119069|Hydrogenophilales	119069|Hydrogenophilales	P	PhoU domain	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
CH2_k127_8247336_3	1163617.SCD_n00391	1.197e-76	258.0	COG0120@1|root,COG0120@2|Bacteria,1MVGR@1224|Proteobacteria,2VH27@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate	rpiA	-	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A,Sugar-bind
CH2_k127_8295778_9	314285.KT71_01325	2.227e-10	61.0	COG1188@1|root,COG1188@2|Bacteria,1MZR6@1224|Proteobacteria,1S8VU@1236|Gammaproteobacteria,1J9VT@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	S4 RNA-binding domain	hslR	GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003727,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009451,GO:0009628,GO:0009987,GO:0016070,GO:0033554,GO:0034605,GO:0034641,GO:0043021,GO:0043023,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	-	ko:K04762	-	-	-	-	ko00000,ko03110	-	-	-	S4
CH2_k127_8295778_4	1121035.AUCH01000016_gene2115	6.122e-138	448.0	COG2198@1|root,COG2206@1|root,COG2198@2|Bacteria,COG2206@2|Bacteria,1RA8P@1224|Proteobacteria,2VNF3@28216|Betaproteobacteria,2KVB7@206389|Rhodocyclales	206389|Rhodocyclales	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_5,Hpt
CH2_k127_8295778_0	1163617.SCD_n02100	0.0	1234.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,2VJIJ@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
CH2_k127_8295778_1	1163617.SCD_n02109	1.046e-184	583.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,2VISR@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
CH2_k127_8295778_2	1288494.EBAPG3_16180	3.084e-174	551.0	COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,2VIM2@28216|Betaproteobacteria,372GQ@32003|Nitrosomonadales	28216|Betaproteobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
CH2_k127_8295778_7	261292.Nit79A3_2380	7.413e-41	151.0	COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,2VU4W@28216|Betaproteobacteria,373IF@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
CH2_k127_8295778_6	1163617.SCD_n02106	8.21e-53	188.0	COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,2VSHZ@28216|Betaproteobacteria	28216|Betaproteobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
CH2_k127_8295778_3	1163617.SCD_n02105	9.996e-149	477.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,2VHX4@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
CH2_k127_8295778_10	1033734.CAET01000079_gene3557	0.0002999	44.0	29S70@1|root,30DBH@2|Bacteria,1UB40@1239|Firmicutes,4IMGK@91061|Bacilli,1ZK45@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_8295778_8	1288494.EBAPG3_16220	7.103e-18	85.0	2EHK0@1|root,33BBV@2|Bacteria,1NGIK@1224|Proteobacteria,2VXN8@28216|Betaproteobacteria,373QW@32003|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	-
CH2_k127_8295778_5	1163617.SCD_n02102	1.403e-62	225.0	COG3852@1|root,COG3852@2|Bacteria,1QVPN@1224|Proteobacteria,2WH69@28216|Betaproteobacteria	28216|Betaproteobacteria	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	pilS	-	2.7.13.3	ko:K02668	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA
CH2_k127_8362634_4	1163617.SCD_n00038	2.528e-93	307.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,2VJPX@28216|Betaproteobacteria	28216|Betaproteobacteria	F	bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
CH2_k127_8362634_0	1163617.SCD_n00037	1.091e-209	659.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,2VH9J@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
CH2_k127_8362634_6	1283284.AZUK01000001_gene1704	3.724e-66	230.0	COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,1S3VN@1236|Gammaproteobacteria,1Y48K@135624|Aeromonadales	135624|Aeromonadales	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	-	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
CH2_k127_8362634_5	1163617.SCD_n00036	1.559e-66	232.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,2VIFT@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	tsaC	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
CH2_k127_8362634_7	519989.ECTPHS_09632	3.514e-36	147.0	COG0642@1|root,COG2205@2|Bacteria,1R9ZT@1224|Proteobacteria,1S3GX@1236|Gammaproteobacteria,1WZ1P@135613|Chromatiales	135613|Chromatiales	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
CH2_k127_8362634_1	1163617.SCD_n02321	1.38e-142	469.0	COG0457@1|root,COG0745@1|root,COG0457@2|Bacteria,COG0745@2|Bacteria,1NNCT@1224|Proteobacteria,2VK0Z@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,TPR_16,TPR_19,TPR_4,TPR_8
CH2_k127_8362634_3	1454004.AW11_00405	2.06e-96	321.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2VHYN@28216|Betaproteobacteria,1KQE8@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	E	ABC transporter	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
CH2_k127_8362634_2	1120999.JONM01000001_gene1269	5.649e-104	342.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,2VJM6@28216|Betaproteobacteria,2KQG5@206351|Neisseriales	206351|Neisseriales	E	Branched-chain amino acid ATP-binding cassette transporter	livG	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
CH2_k127_8372196_3	1163617.SCD_n02683	7.102e-15	77.0	COG2165@1|root,COG2165@2|Bacteria,1N7HN@1224|Proteobacteria,2VVYH@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K10924	ko05111,map05111	-	-	-	ko00000,ko00001,ko02044	-	-	-	N_methyl
CH2_k127_8372196_1	1132855.KB913035_gene1400	6.254e-44	165.0	COG2165@1|root,COG2165@2|Bacteria,1N7HN@1224|Proteobacteria,2VUKR@28216|Betaproteobacteria,2KNTY@206350|Nitrosomonadales	206350|Nitrosomonadales	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K10924	ko05111,map05111	-	-	-	ko00000,ko00001,ko02044	-	-	-	N_methyl
CH2_k127_8372196_2	1163617.SCD_n02684	3.419e-34	141.0	COG2165@1|root,COG2165@2|Bacteria,1R2GE@1224|Proteobacteria,2VYFF@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_8372196_0	1163617.SCD_n02685	8.704e-164	520.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,2VJ2Y@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	Type II secretion system	pilC3	-	-	ko:K02455,ko:K12278	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
CH2_k127_8426628_3	580332.Slit_2193	4.068e-26	111.0	COG3093@1|root,COG3093@2|Bacteria,1PSY1@1224|Proteobacteria,2WAF3@28216|Betaproteobacteria,44WMR@713636|Nitrosomonadales	28216|Betaproteobacteria	K	TIGRFAM addiction module antidote protein, HigA family	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
CH2_k127_8426628_2	1047013.AQSP01000098_gene2557	1.124e-30	123.0	COG3549@1|root,COG3549@2|Bacteria,2NRG4@2323|unclassified Bacteria	2|Bacteria	S	RelE-like toxin of type II toxin-antitoxin system HigB	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
CH2_k127_8426628_1	1163617.SCD_n02506	4.86e-45	171.0	2DP0A@1|root,3300Q@2|Bacteria,1N78Y@1224|Proteobacteria,2VVZ5@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM Sporulation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
CH2_k127_8426628_0	1288494.EBAPG3_23440	4.141e-70	244.0	COG1521@1|root,COG1521@2|Bacteria,1MUYA@1224|Proteobacteria,2VK1G@28216|Betaproteobacteria,3733Y@32003|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33,6.3.4.15	ko:K01947,ko:K03525	ko00770,ko00780,ko01100,map00770,map00780,map01100	M00120	R01074,R02971,R03018,R04391,R05145	RC00002,RC00017,RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko00002,ko01000	-	-	-	BPL_C,BPL_LplA_LipB,Pan_kinase
CH2_k127_8444422_5	296591.Bpro_0409	1.194e-53	192.0	COG5622@1|root,COG5622@2|Bacteria,1N6XP@1224|Proteobacteria,2VSGR@28216|Betaproteobacteria	28216|Betaproteobacteria	N	Protein required for attachment to host cells	-	-	-	-	-	-	-	-	-	-	-	-	Host_attach
CH2_k127_8444422_6	1123393.KB891329_gene1059	5.595e-52	190.0	COG1514@1|root,COG1514@2|Bacteria,1RDB2@1224|Proteobacteria,2VTZU@28216|Betaproteobacteria,1KSVF@119069|Hydrogenophilales	119069|Hydrogenophilales	J	LigT like Phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	LigT_PEase
CH2_k127_8444422_3	1123393.KB891329_gene1058	8.997e-74	250.0	COG0245@1|root,COG0245@2|Bacteria,1MVHA@1224|Proteobacteria,2VR7F@28216|Betaproteobacteria,1KRPQ@119069|Hydrogenophilales	119069|Hydrogenophilales	I	YgbB family	-	-	4.6.1.12	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
CH2_k127_8444422_2	1288494.EBAPG3_10600	2.899e-89	300.0	COG1211@1|root,COG1211@2|Bacteria,1MY3B@1224|Proteobacteria,2VMD6@28216|Betaproteobacteria,372DA@32003|Nitrosomonadales	28216|Betaproteobacteria	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60,4.6.1.12	ko:K00991,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
CH2_k127_8444422_1	1163617.SCD_n01758	7.698e-106	349.0	COG1355@1|root,COG1355@2|Bacteria,1MXK5@1224|Proteobacteria,2VKXP@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Belongs to the MEMO1 family	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,Memo
CH2_k127_8444422_4	580332.Slit_1845	1.703e-66	233.0	COG2078@1|root,COG2078@2|Bacteria,1RJP4@1224|Proteobacteria,2VRE4@28216|Betaproteobacteria,44WF2@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM AMMECR1 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AMMECR1
CH2_k127_8444422_0	338969.Rfer_0396	1.873e-116	384.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,2VINV@28216|Betaproteobacteria,4AGJH@80864|Comamonadaceae	28216|Betaproteobacteria	C	Radical SAM superfamily	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
CH2_k127_8459369_1	305700.B447_19454	3.526e-75	255.0	COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,2VI91@28216|Betaproteobacteria,2KUT2@206389|Rhodocyclales	206389|Rhodocyclales	K	RNA polymerase sigma	rpoH	-	-	ko:K03089	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r4
CH2_k127_8459369_0	391612.CY0110_06284	1.156e-80	279.0	COG3447@1|root,COG5001@1|root,COG3447@2|Bacteria,COG5001@2|Bacteria,1GD2B@1117|Cyanobacteria,3KJWM@43988|Cyanothece	1117|Cyanobacteria	T	MASE1	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,MASE1
CH2_k127_8518527_1	1163617.SCD_n01588	2.944e-29	120.0	2D186@1|root,32TA3@2|Bacteria,1N5ZE@1224|Proteobacteria,2W4FH@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_8518527_0	1163617.SCD_n01510	2.21e-195	617.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,2VIE0@28216|Betaproteobacteria	28216|Betaproteobacteria	L	DNA polymerase III is a complex multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3 to 5 exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3,DNA_pol3_tau_5
CH2_k127_8530327_1	1123393.KB891331_gene2852	1.005e-102	338.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,2VIT4@28216|Betaproteobacteria,1KRE2@119069|Hydrogenophilales	119069|Hydrogenophilales	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CH2_k127_8530327_0	1163617.SCD_n00284	5.068e-132	424.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,2VHBM@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
CH2_k127_8530327_3	1485544.JQKP01000001_gene918	1.048e-26	117.0	COG3165@1|root,COG3165@2|Bacteria,1N314@1224|Proteobacteria,2VU2B@28216|Betaproteobacteria,44WEV@713636|Nitrosomonadales	28216|Betaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K03690	-	-	-	-	ko00000	-	-	-	SCP2
CH2_k127_8530327_2	1123393.KB891331_gene2855	5.688e-36	137.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,2VJ07@28216|Betaproteobacteria,1KRE6@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
CH2_k127_8540175_5	261292.Nit79A3_0451	1.011e-24	104.0	COG0144@1|root,COG0144@2|Bacteria,1MWPE@1224|Proteobacteria,2VI4V@28216|Betaproteobacteria,371PC@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	sun	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
CH2_k127_8540175_3	1163617.SCD_n00012	1.302e-38	151.0	29CX4@1|root,2ZZV8@2|Bacteria,1RFY7@1224|Proteobacteria,2VR98@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF4390)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4390
CH2_k127_8540175_0	1163617.SCD_n00013	1.317e-291	910.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,2VIDI@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	ntrY	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,PAS_7,PAS_8
CH2_k127_8540175_1	1163617.SCD_n00014	2.066e-170	545.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VKD8@28216|Betaproteobacteria	28216|Betaproteobacteria	T	response regulator	ntrX	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activ_2
CH2_k127_8540175_2	1123368.AUIS01000003_gene1841	2.689e-40	151.0	COG4783@1|root,COG4783@2|Bacteria,1N76P@1224|Proteobacteria,1T4CE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
CH2_k127_8540175_4	1163617.SCD_n00015	4.862e-33	131.0	COG3158@1|root,COG3158@2|Bacteria,1MUVH@1224|Proteobacteria,2VH9I@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Transport of potassium into the cell	kup	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
CH2_k127_8576895_1	1163617.SCD_n00794	1.617e-233	726.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,2VH1K@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Belongs to the ClpA ClpB family	clpA	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
CH2_k127_8576895_6	85643.Tmz1t_1250	2.838e-44	163.0	COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,2VSCU@28216|Betaproteobacteria,2KWPQ@206389|Rhodocyclales	206389|Rhodocyclales	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
CH2_k127_8576895_0	1163617.SCD_n00688	1.816e-239	746.0	COG0538@1|root,COG0538@2|Bacteria,1MW3J@1224|Proteobacteria,2VHVD@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Isocitrate dehydrogenase	icd	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
CH2_k127_8576895_2	1163617.SCD_n00687	8.079e-97	318.0	COG1187@1|root,COG1187@2|Bacteria,1R9VV@1224|Proteobacteria,2VQAQ@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Belongs to the pseudouridine synthase RsuA family	rluE	-	5.4.99.20	ko:K06181	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
CH2_k127_8576895_3	1163617.SCD_n00783	1.865e-67	231.0	COG1051@1|root,COG1051@2|Bacteria,1N03W@1224|Proteobacteria,2VRC0@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Belongs to the Nudix hydrolase family. NudJ subfamily	nudJ	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CH2_k127_8576895_5	1163617.SCD_n00784	2.36e-58	207.0	2CDCV@1|root,308Y1@2|Bacteria,1N74F@1224|Proteobacteria,2VSMP@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_8576895_4	1163617.SCD_n00785	1.418e-62	219.0	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,2VJRR@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
CH2_k127_8590823_0	580332.Slit_2351	5.843e-226	701.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,2VJ1W@28216|Betaproteobacteria,44VKN@713636|Nitrosomonadales	28216|Betaproteobacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
CH2_k127_8590823_3	1163617.SCD_n02619	1.456e-83	281.0	COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,2VKKJ@28216|Betaproteobacteria	28216|Betaproteobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
CH2_k127_8590823_2	261292.Nit79A3_3455	1.694e-86	291.0	COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,2VQNU@28216|Betaproteobacteria,37239@32003|Nitrosomonadales	28216|Betaproteobacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
CH2_k127_8590823_1	1163617.SCD_n02621	3.354e-176	555.0	COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,2VHU0@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
CH2_k127_8679854_3	1288494.EBAPG3_28200	5.252e-44	161.0	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,2VI5Q@28216|Betaproteobacteria,37205@32003|Nitrosomonadales	28216|Betaproteobacteria	D	Peptidoglycan polymerase that is essential for cell division	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
CH2_k127_8679854_1	1163617.SCD_n02485	4.566e-172	552.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,2VH32@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
CH2_k127_8679854_0	1163617.SCD_n02484	3.689e-229	717.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,2VIKZ@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CH2_k127_8679854_2	1163617.SCD_n02483	1.954e-112	371.0	COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,2VI7I@28216|Betaproteobacteria	28216|Betaproteobacteria	M	cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
CH2_k127_8685768_2	1163617.SCD_n00973	9.707e-95	319.0	COG0484@1|root,COG0484@2|Bacteria,1Q629@1224|Proteobacteria,2VJ8G@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
CH2_k127_8685768_0	1163617.SCD_n00974	5.505e-242	770.0	COG1729@1|root,COG1729@2|Bacteria,1MZ7N@1224|Proteobacteria,2VNYC@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_8685768_3	159087.Daro_3772	6.828e-59	215.0	COG4235@1|root,COG4235@2|Bacteria,1PE9I@1224|Proteobacteria,2W1Y3@28216|Betaproteobacteria	28216|Betaproteobacteria	O	cytochrome complex assembly	-	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	-
CH2_k127_8685768_1	640081.Dsui_2875	6.322e-125	415.0	COG1538@1|root,COG1538@2|Bacteria,1MWX5@1224|Proteobacteria,2VHU4@28216|Betaproteobacteria,2KXX0@206389|Rhodocyclales	206389|Rhodocyclales	M	CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin)	-	-	-	-	-	-	-	-	-	-	-	-	OEP
CH2_k127_8685768_4	640081.Dsui_2876	2.878e-26	113.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,2VH9K@28216|Betaproteobacteria,2KWJY@206389|Rhodocyclales	206389|Rhodocyclales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	HlyD_D23
CH2_k127_8689645_5	1163617.SCD_n00561	1.954e-41	157.0	COG1778@1|root,COG1778@2|Bacteria,1RH85@1224|Proteobacteria,2VRQX@28216|Betaproteobacteria	28216|Betaproteobacteria	M	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family	kdsC	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase,Hydrolase_3
CH2_k127_8689645_2	1163617.SCD_n00562	6.641e-151	484.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,2VI24@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Belongs to the SIS family. GutQ KpsF subfamily	kdsD	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
CH2_k127_8689645_0	1163617.SCD_n00563	4.495e-271	848.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,2VHQQ@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (cpa2) transporter (TC 2.A.37) family	kefB	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
CH2_k127_8689645_6	1469245.JFBG01000027_gene1443	1.289e-33	139.0	COG2165@1|root,COG2165@2|Bacteria,1REMT@1224|Proteobacteria,1SF74@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
CH2_k127_8689645_3	1198452.Jab_2c02510	3.357e-70	244.0	2EMEM@1|root,33F3F@2|Bacteria,1NK08@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_8689645_4	1349767.GJA_2100	3.304e-56	208.0	2DNTZ@1|root,32Z4F@2|Bacteria,1NA30@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
CH2_k127_8689645_1	1123392.AQWL01000004_gene2758	6.848e-162	527.0	COG0642@1|root,COG0642@2|Bacteria,1R49A@1224|Proteobacteria,2VKU5@28216|Betaproteobacteria,1KSY8@119069|Hydrogenophilales	119069|Hydrogenophilales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_8765615_2	1163617.SCD_n02045	4.632e-102	339.0	COG0614@1|root,COG0614@2|Bacteria,1MWVF@1224|Proteobacteria,2VJ7T@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Pfam Periplasmic binding protein	btuF	-	-	ko:K02016,ko:K06858	ko02010,map02010	M00240,M00241	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.13,3.A.1.14	-	-	Peripla_BP_2
CH2_k127_8765615_3	1123392.AQWL01000003_gene417	4.72e-65	228.0	COG0406@1|root,COG0406@2|Bacteria,1RHAT@1224|Proteobacteria,2WGE2@28216|Betaproteobacteria,1KSQD@119069|Hydrogenophilales	119069|Hydrogenophilales	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
CH2_k127_8765615_4	1279019.ARQK01000053_gene2079	2.999e-49	178.0	COG0662@1|root,COG0662@2|Bacteria,1N1XN@1224|Proteobacteria,1SJ46@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Mannose-6-phosphate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CH2_k127_8765615_1	472759.Nhal_0229	1.031e-162	527.0	COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,1MU9M@1224|Proteobacteria,1RPG3@1236|Gammaproteobacteria,1WW4S@135613|Chromatiales	135613|Chromatiales	S	AAA domain	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33,APH
CH2_k127_8765615_5	1168034.FH5T_01450	7.597e-34	131.0	COG3369@1|root,COG3369@2|Bacteria,4NW9E@976|Bacteroidetes	976|Bacteroidetes	S	Iron-binding zinc finger CDGSH type	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
CH2_k127_8765615_0	1123368.AUIS01000001_gene1868	2.863e-213	665.0	COG2876@1|root,COG2876@2|Bacteria,1QVAD@1224|Proteobacteria,1S11K@1236|Gammaproteobacteria,2NBQA@225057|Acidithiobacillales	225057|Acidithiobacillales	E	DAHP synthetase I family	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
CH2_k127_8765615_6	1163617.SCD_n01946	3.954e-09	62.0	2ENVQ@1|root,33GGS@2|Bacteria,1NGVT@1224|Proteobacteria,2VY6X@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF2934)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2934
CH2_k127_8785156_1	292415.Tbd_1023	9.882e-160	511.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,2VHW4@28216|Betaproteobacteria,1KS1H@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
CH2_k127_8785156_4	105559.Nwat_1220	7.247e-90	308.0	COG0837@1|root,COG0837@2|Bacteria,1MVFI@1224|Proteobacteria,1RNUY@1236|Gammaproteobacteria,1WW69@135613|Chromatiales	135613|Chromatiales	G	Belongs to the bacterial glucokinase family	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucokinase
CH2_k127_8785156_3	1123393.KB891316_gene1260	5.233e-110	364.0	COG3954@1|root,COG3954@2|Bacteria,1MWN9@1224|Proteobacteria,2VHZD@28216|Betaproteobacteria,1KSYR@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Phosphoribulokinase / Uridine kinase family	-	-	2.7.1.19	ko:K00855	ko00710,ko01100,ko01120,ko01200,map00710,map01100,map01120,map01200	M00165,M00166	R01523	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PRK
CH2_k127_8785156_0	1163617.SCD_n00900	9.82e-222	713.0	COG3829@1|root,COG5001@1|root,COG3829@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VKYE@28216|Betaproteobacteria	28216|Betaproteobacteria	T	EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
CH2_k127_8785156_6	1163617.SCD_n02821	1.392e-59	213.0	COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,2VKFN@28216|Betaproteobacteria	28216|Betaproteobacteria	M	PFAM Lytic transglycosylase catalytic	slt	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	DUF4124,SLT
CH2_k127_8785156_7	1123368.AUIS01000016_gene2543	2.894e-56	207.0	COG2165@1|root,COG2165@2|Bacteria,1MZ5I@1224|Proteobacteria,1SBEY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	Type II secretory pathway pseudopilin	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_8785156_8	292415.Tbd_1441	1.834e-46	170.0	COG2165@1|root,COG2165@2|Bacteria,1N1QJ@1224|Proteobacteria,2VTYJ@28216|Betaproteobacteria	28216|Betaproteobacteria	U	Type II secretion system protein G	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
CH2_k127_8785156_5	1123368.AUIS01000016_gene2545	6.996e-66	229.0	COG4968@1|root,COG4968@2|Bacteria,1QVCD@1224|Proteobacteria,1T58B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
CH2_k127_8785156_2	1144319.PMI16_01877	3.028e-116	390.0	COG4796@1|root,COG4796@2|Bacteria,1QUY7@1224|Proteobacteria,2VJ8Z@28216|Betaproteobacteria,472RY@75682|Oxalobacteraceae	28216|Betaproteobacteria	U	Secretin and TonB N terminus short domain	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Cohesin,STN,Secretin,Secretin_N
CH2_k127_8817092_0	1165096.ARWF01000001_gene1417	1.081e-83	297.0	2CG4C@1|root,2Z8MQ@2|Bacteria,1R6PQ@1224|Proteobacteria,2VHKG@28216|Betaproteobacteria,2KKMA@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_8817092_1	1123393.KB891328_gene585	6.011e-25	113.0	2E6RE@1|root,331BH@2|Bacteria,1N8K0@1224|Proteobacteria,2VWUF@28216|Betaproteobacteria,1KSR3@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_8869518_0	522306.CAP2UW1_2930	3.106e-137	447.0	COG4591@1|root,COG4591@2|Bacteria,1R4Q2@1224|Proteobacteria,2VP40@28216|Betaproteobacteria	28216|Betaproteobacteria	M	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CH2_k127_8869518_2	765869.BDW_11595	1.572e-25	117.0	COG2834@1|root,COG2834@2|Bacteria,1RE9C@1224|Proteobacteria,42U1U@68525|delta/epsilon subdivisions,2WQTI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
CH2_k127_8869518_1	522306.CAP2UW1_1633	3.964e-117	381.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2VQWS@28216|Betaproteobacteria	28216|Betaproteobacteria	V	abc transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CH2_k127_8948029_0	1163617.SCD_n00618	3.974e-320	985.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,2VHF3@28216|Betaproteobacteria	28216|Betaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
CH2_k127_8948029_5	1163617.SCD_n00617	6.077e-57	201.0	COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,2VSG7@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
CH2_k127_8948029_4	1163617.SCD_n00616	1.83e-78	265.0	COG0244@1|root,COG0244@2|Bacteria,1RAN5@1224|Proteobacteria,2VQ7A@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
CH2_k127_8948029_1	1163617.SCD_n00615	4.661e-117	379.0	COG0081@1|root,COG0081@2|Bacteria,1MUE6@1224|Proteobacteria,2VHDK@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
CH2_k127_8948029_3	1163617.SCD_n00614	3.874e-81	271.0	COG0080@1|root,COG0080@2|Bacteria,1RA2M@1224|Proteobacteria,2VPZW@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
CH2_k127_8948029_2	640081.Dsui_0371	7.763e-94	310.0	COG0250@1|root,COG0250@2|Bacteria,1MU14@1224|Proteobacteria,2VKUA@28216|Betaproteobacteria,2KUIE@206389|Rhodocyclales	206389|Rhodocyclales	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
CH2_k127_8948029_6	1163617.SCD_n00612	1.118e-38	149.0	COG0690@1|root,COG0690@2|Bacteria,1RDI9@1224|Proteobacteria,2VUPV@28216|Betaproteobacteria	28216|Betaproteobacteria	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
CH2_k127_8948029_7	1122169.AREN01000056_gene2019	9.989e-08	53.0	COG0690@1|root,COG0690@2|Bacteria,1RDI9@1224|Proteobacteria,1S3PA@1236|Gammaproteobacteria,1JECV@118969|Legionellales	118969|Legionellales	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
CH2_k127_8969051_3	395494.Galf_0604	3.686e-58	207.0	COG0593@1|root,COG0593@2|Bacteria,1MVW6@1224|Proteobacteria,2VSFD@28216|Betaproteobacteria,44VQF@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Bacterial dnaA  protein	hda	-	-	ko:K10763	-	-	-	-	ko00000,ko03032	-	-	-	Bac_DnaA
CH2_k127_8969051_2	1049564.TevJSym_aa01860	4.246e-96	319.0	COG1051@1|root,COG1051@2|Bacteria,1QTT4@1224|Proteobacteria,1RQ35@1236|Gammaproteobacteria,1J69Z@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	COG1051 ADP-ribose pyrophosphatase	nuhA	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CH2_k127_8969051_0	1123392.AQWL01000002_gene1974	8.095e-157	501.0	COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,2VH6N@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
CH2_k127_8969051_1	1163617.SCD_n02728	2.43e-145	478.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria	28216|Betaproteobacteria	NT	chemotaxis	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
CH2_k127_8972333_1	1163617.SCD_n01461	5.785e-141	449.0	COG0730@1|root,COG0730@2|Bacteria	2|Bacteria	S	response to heat	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
CH2_k127_8972333_4	1163617.SCD_n01459	7.65e-60	209.0	COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,2VUBZ@28216|Betaproteobacteria	28216|Betaproteobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
CH2_k127_8972333_2	243365.CV_2644	1.391e-82	290.0	COG0745@1|root,COG2172@1|root,COG2208@1|root,COG0745@2|Bacteria,COG2172@2|Bacteria,COG2208@2|Bacteria,1N4K5@1224|Proteobacteria,2VKGP@28216|Betaproteobacteria,2KSCH@206351|Neisseriales	206351|Neisseriales	T	Sigma factor PP2C-like phosphatases	-	-	-	ko:K20977	ko02020,ko02025,map02020,map02025	M00820	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HATPase_c_2,Response_reg,SpoIIE
CH2_k127_8972333_0	1163617.SCD_n01458	6.71e-225	702.0	COG1055@1|root,COG1055@2|Bacteria,1MUX4@1224|Proteobacteria,2VNCF@28216|Betaproteobacteria	28216|Betaproteobacteria	U	Involved in arsenical resistance. Thought to form the channel of an arsenite pump	arsB	-	-	ko:K03893	-	-	-	-	ko00000,ko02000	2.A.45.1,3.A.4.1	-	-	ArsB
CH2_k127_8972333_6	1541065.JRFE01000009_gene4500	4.058e-23	111.0	COG2931@1|root,COG2931@2|Bacteria,1GCGV@1117|Cyanobacteria,3VKJD@52604|Pleurocapsales	1117|Cyanobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
CH2_k127_8972333_5	1238182.C882_0839	8.662e-43	164.0	COG2197@1|root,COG2197@2|Bacteria,1P4TD@1224|Proteobacteria,2U06A@28211|Alphaproteobacteria,2JRXM@204441|Rhodospirillales	204441|Rhodospirillales	T	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CH2_k127_8972333_3	876269.ARWA01000001_gene83	1.26e-77	282.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,2TR1M@28211|Alphaproteobacteria,3NAY1@45404|Beijerinckiaceae	28211|Alphaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_7,Response_reg,dCache_1
CH2_k127_8997938_4	595537.Varpa_2844	4.384e-130	420.0	COG4239@1|root,COG4239@2|Bacteria,1MUM5@1224|Proteobacteria,2VHVN@28216|Betaproteobacteria,4AAK4@80864|Comamonadaceae	28216|Betaproteobacteria	P	binding-protein-dependent transport systems inner membrane component	dppC2	-	-	ko:K13895	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	BPD_transp_1,OppC_N
CH2_k127_8997938_2	93220.LV28_24120	7.974e-161	514.0	COG4174@1|root,COG4174@2|Bacteria,1MVKE@1224|Proteobacteria,2VIBF@28216|Betaproteobacteria,1K014@119060|Burkholderiaceae	28216|Betaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	yejB	-	-	ko:K13894	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	BPD_transp_1
CH2_k127_8997938_0	555778.Hneap_0393	4.921e-216	686.0	COG4166@1|root,COG4166@2|Bacteria	2|Bacteria	E	transmembrane transport	-	-	-	ko:K02035,ko:K13893	ko02010,ko02024,map02010,map02024	M00239,M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
CH2_k127_8997938_3	1163617.SCD_n01159	1.781e-149	475.0	COG0623@1|root,COG0623@2|Bacteria,1MV05@1224|Proteobacteria,2VIHE@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Enoyl- acyl-carrier-protein reductase NADH	fabI	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CH2_k127_8997938_1	1163617.SCD_n01767	5.8e-184	595.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,2VJCZ@28216|Betaproteobacteria	28216|Betaproteobacteria	O	peptidylprolyl isomerase	ppiD	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
CH2_k127_8997938_8	981223.AIED01000149_gene464	3.269e-07	53.0	2EJ6D@1|root,33CXK@2|Bacteria,1NHGW@1224|Proteobacteria,1SGZR@1236|Gammaproteobacteria,3NQBV@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_8997938_6	1163617.SCD_n01770	2.04e-41	153.0	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,2VU4V@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hupB	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
CH2_k127_8997938_5	1123392.AQWL01000008_gene1180	1.066e-113	369.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,2VIAU@28216|Betaproteobacteria,1KRFW@119069|Hydrogenophilales	119069|Hydrogenophilales	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
CH2_k127_9028516_0	1163617.SCD_n01809	3.425e-192	603.0	COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,2VID7@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
CH2_k127_9028516_4	1163617.SCD_n01810	7.956e-52	194.0	COG1426@1|root,COG4787@1|root,COG1426@2|Bacteria,COG4787@2|Bacteria,1N240@1224|Proteobacteria,2VVFV@28216|Betaproteobacteria	28216|Betaproteobacteria	N	Transcriptional regulator	-	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25
CH2_k127_9028516_2	1163617.SCD_n01811	2.299e-77	266.0	COG3063@1|root,COG3063@2|Bacteria,1MXPC@1224|Proteobacteria,2VNC8@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	Type IV pilus biogenesis stability protein PilW	pilF	-	-	ko:K02656	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	TPR_16,TPR_17,TPR_19,TPR_2,TPR_8
CH2_k127_9028516_1	582744.Msip34_1719	1.489e-189	596.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,2VIBN@28216|Betaproteobacteria,2KM5F@206350|Nitrosomonadales	206350|Nitrosomonadales	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
CH2_k127_9028516_3	522306.CAP2UW1_2107	1.812e-74	252.0	COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,2VQ2J@28216|Betaproteobacteria,1KQ0A@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
CH2_k127_9054680_1	1163617.SCD_n00585	3.997e-26	108.0	COG0040@1|root,COG0040@2|Bacteria,1MUCY@1224|Proteobacteria,2VIF9@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG
CH2_k127_9054680_0	1163617.SCD_n01469	9.208e-164	530.0	COG0745@1|root,COG2198@1|root,COG2199@1|root,COG0745@2|Bacteria,COG2198@2|Bacteria,COG3706@2|Bacteria,1MVWM@1224|Proteobacteria,2VK4W@28216|Betaproteobacteria	28216|Betaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Hpt,Response_reg
CH2_k127_9055369_2	1288494.EBAPG3_21430	7.659e-246	760.0	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,2VHEC@28216|Betaproteobacteria,371Z7@32003|Nitrosomonadales	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
CH2_k127_9055369_4	1163617.SCD_n00943	3.973e-74	251.0	COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,2VQD9@28216|Betaproteobacteria	28216|Betaproteobacteria	C	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit	nuoE	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
CH2_k127_9055369_1	1163617.SCD_n00944	2.615e-247	766.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,2VJJ1@28216|Betaproteobacteria	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
CH2_k127_9055369_0	1163617.SCD_n00945	0.0	1044.0	COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,2VJYV@28216|Betaproteobacteria	28216|Betaproteobacteria	C	NADH-quinone oxidoreductase	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
CH2_k127_9055369_3	1131553.JIBI01000007_gene1190	6.574e-88	295.0	COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,2VHD0@28216|Betaproteobacteria,371TY@32003|Nitrosomonadales	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
CH2_k127_9094112_1	1163617.SCD_n01316	2.379e-90	301.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,2VM1X@28216|Betaproteobacteria	28216|Betaproteobacteria	U	General secretion pathway protein F	gspF	-	-	ko:K02455	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
CH2_k127_9094112_0	1500894.JQNN01000001_gene3449	3.753e-109	373.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,2VIXC@28216|Betaproteobacteria,477GD@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	Subtilase family	mprA	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
CH2_k127_9094112_4	1163617.SCD_n01317	8.916e-43	165.0	COG1266@1|root,COG1266@2|Bacteria,1ND7U@1224|Proteobacteria	1224|Proteobacteria	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
CH2_k127_9094112_2	1123368.AUIS01000003_gene1762	4.132e-69	237.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,1S3VS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	General Secretion Pathway protein	gspG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
CH2_k127_9094112_5	1163617.SCD_n01319	1.093e-41	159.0	COG2165@1|root,COG2165@2|Bacteria,1N8AD@1224|Proteobacteria,2VWBA@28216|Betaproteobacteria	28216|Betaproteobacteria	U	general secretion pathway protein	gspH	-	-	ko:K02457	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	GspH,N_methyl
CH2_k127_9094112_6	580332.Slit_0494	7.433e-26	113.0	COG2165@1|root,COG2165@2|Bacteria,1N737@1224|Proteobacteria	1224|Proteobacteria	NU	General secretion pathway protein I	gspI	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	ko:K02458	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSI
CH2_k127_9094112_3	1163617.SCD_n01321	3.054e-60	214.0	COG4795@1|root,COG4795@2|Bacteria	2|Bacteria	U	General secretion pathway protein	gspJ	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776	-	ko:K02459	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSJ
CH2_k127_9094112_7	1163617.SCD_n01322	3.174e-18	85.0	COG3156@1|root,COG3156@2|Bacteria,1RBNV@1224|Proteobacteria,2VS9P@28216|Betaproteobacteria	28216|Betaproteobacteria	U	general secretion pathway protein K	gspK	-	-	ko:K02460	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSK
CH2_k127_9155055_8	748280.NH8B_2654	6.511e-07	57.0	2DP3X@1|root,330EQ@2|Bacteria,1N9M7@1224|Proteobacteria,2VYWC@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_Omp,PXPV,Rick_17kDa_Anti
CH2_k127_9155055_0	1163617.SCD_n02514	1.075e-202	636.0	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,2VHF7@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,S4_2,tRNA-synt_1b
CH2_k127_9155055_1	1163617.SCD_n02515	3.194e-180	574.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2VHBS@28216|Betaproteobacteria	28216|Betaproteobacteria	M	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CH2_k127_9155055_3	1163617.SCD_n02516	1.45e-149	481.0	COG2377@1|root,COG2377@2|Bacteria,1MV4E@1224|Proteobacteria,2VHCE@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
CH2_k127_9155055_2	1123368.AUIS01000041_gene1	4.112e-163	521.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,1RNDK@1236|Gammaproteobacteria,2NC58@225057|Acidithiobacillales	225057|Acidithiobacillales	C	Belongs to the citrate synthase family	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
CH2_k127_9155055_4	1485544.JQKP01000004_gene456	4.886e-62	214.0	COG0316@1|root,COG0316@2|Bacteria,1RHCW@1224|Proteobacteria,2VR2M@28216|Betaproteobacteria,44VT4@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Required for insertion of 4Fe-4S clusters	erpA	-	-	ko:K15724	-	-	-	-	ko00000	-	-	-	Fe-S_biosyn
CH2_k127_9155055_7	1163617.SCD_n02518	2.775e-50	181.0	COG1664@1|root,COG1664@2|Bacteria,1MZN0@1224|Proteobacteria,2VTZQ@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Integral membrane protein CcmA involved in cell shape determination	ccmA	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
CH2_k127_9155055_6	1163617.SCD_n02519	3.256e-56	206.0	28IJP@1|root,2Z8KI@2|Bacteria,1R9DP@1224|Proteobacteria,2VHRX@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_9155055_5	1163617.SCD_n02520	1.455e-61	213.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,2VJD7@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
CH2_k127_9165261_4	1163617.SCD_n00737	4.296e-72	254.0	COG2887@1|root,COG3893@1|root,COG2887@2|Bacteria,COG3893@2|Bacteria,1MY2G@1224|Proteobacteria,2VJF3@28216|Betaproteobacteria	28216|Betaproteobacteria	L	PD-(D/E)XK nuclease superfamily	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1
CH2_k127_9165261_6	305700.B447_01281	5.197e-57	199.0	COG1146@1|root,COG1146@2|Bacteria,1RH5I@1224|Proteobacteria,2VSJ0@28216|Betaproteobacteria,2KWJV@206389|Rhodocyclales	206389|Rhodocyclales	C	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions	fdxA	-	-	ko:K05524	-	-	-	-	ko00000	-	-	-	DUF3470,Fer4,Fer4_4
CH2_k127_9165261_8	1121116.KB894766_gene492	9.555e-15	78.0	2B9KW@1|root,322Z5@2|Bacteria,1RJJB@1224|Proteobacteria,2VSVB@28216|Betaproteobacteria,4AFVT@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_9165261_5	1163617.SCD_n00736	3.88e-64	220.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,2VSHX@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
CH2_k127_9165261_0	1266925.JHVX01000006_gene2113	1.098e-250	777.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,2VJ2E@28216|Betaproteobacteria,372DQ@32003|Nitrosomonadales	28216|Betaproteobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
CH2_k127_9165261_1	159087.Daro_0683	1.036e-202	640.0	COG1055@1|root,COG1055@2|Bacteria,1MUH8@1224|Proteobacteria,2VPFR@28216|Betaproteobacteria,2KXRJ@206389|Rhodocyclales	206389|Rhodocyclales	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
CH2_k127_9165261_7	1122236.KB905146_gene1948	1.532e-35	135.0	COG0254@1|root,COG0254@2|Bacteria,1MZ69@1224|Proteobacteria,2VW5V@28216|Betaproteobacteria,2KP7H@206350|Nitrosomonadales	206350|Nitrosomonadales	J	Ribosomal protein L31	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_L31
CH2_k127_9165261_2	1163617.SCD_n00733	1.773e-194	622.0	COG4784@1|root,COG4784@2|Bacteria,1QTT7@1224|Proteobacteria,2WHEI@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
CH2_k127_9165261_3	1163617.SCD_n01493	3.287e-123	398.0	COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,2VIYB@28216|Betaproteobacteria	28216|Betaproteobacteria	C	malic enzyme	maeB	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_DH,Malic_M,PTA_PTB,malic
CH2_k127_9223951_8	666681.M301_1350	7.831e-38	143.0	COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,2VHCT@28216|Betaproteobacteria,2KKZF@206350|Nitrosomonadales	206350|Nitrosomonadales	L	TIGRFAM hydrolase, TatD family	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
CH2_k127_9223951_3	1165096.ARWF01000001_gene334	6.381e-87	293.0	COG1235@1|root,COG1235@2|Bacteria,1MVJH@1224|Proteobacteria,2VKJK@28216|Betaproteobacteria,2KMIB@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Beta-lactamase superfamily domain	-	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
CH2_k127_9223951_10	323848.Nmul_A1380	8.822e-32	132.0	COG0666@1|root,COG0666@2|Bacteria,1N952@1224|Proteobacteria,2VPIV@28216|Betaproteobacteria,3733C@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Ankyrin repeat	arp3	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank_2,Ank_3,Ank_4,Ank_5
CH2_k127_9223951_4	1283300.ATXB01000001_gene771	3.081e-68	234.0	COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,1RNVK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrB	GO:0003674,GO:0003824,GO:0008113,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016667,GO:0016671,GO:0044419,GO:0051704,GO:0055114	1.8.4.11,1.8.4.12	ko:K07305,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
CH2_k127_9223951_9	1266925.JHVX01000014_gene1569	1.714e-35	143.0	COG3218@1|root,COG3218@2|Bacteria,1N8NT@1224|Proteobacteria,2VTC7@28216|Betaproteobacteria,3734P@32003|Nitrosomonadales	28216|Betaproteobacteria	S	ABC-type transport auxiliary lipoprotein component	-	-	-	ko:K18480	-	M00669	-	-	ko00000,ko00002,ko02000	3.A.1.27.1	-	-	ABC_trans_aux
CH2_k127_9223951_5	1288494.EBAPG3_22970	9.439e-60	219.0	COG1463@1|root,COG1463@2|Bacteria,1MU4B@1224|Proteobacteria,2VJHA@28216|Betaproteobacteria,372IQ@32003|Nitrosomonadales	28216|Betaproteobacteria	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
CH2_k127_9223951_2	1288494.EBAPG3_22960	1.465e-94	319.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,2VJK6@28216|Betaproteobacteria,37269@32003|Nitrosomonadales	28216|Betaproteobacteria	Q	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
CH2_k127_9223951_0	153948.NAL212_2362	2.032e-115	383.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,2VH5N@28216|Betaproteobacteria,371SA@32003|Nitrosomonadales	28216|Betaproteobacteria	Q	Permease MlaE	mlaE_2	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
CH2_k127_9223951_6	1123393.KB891329_gene955	9.659e-42	159.0	2B0UD@1|root,31T6Y@2|Bacteria,1PWD8@1224|Proteobacteria,2WBXZ@28216|Betaproteobacteria,1KSSR@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_9223951_7	1163617.SCD_n01487	5.843e-41	154.0	COG1393@1|root,COG1393@2|Bacteria,1MZ6S@1224|Proteobacteria,2VUB7@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Belongs to the ArsC family	yffB	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC
CH2_k127_9223951_1	153948.NAL212_2292	1.018e-94	312.0	COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,2VHRF@28216|Betaproteobacteria,372MG@32003|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls	dapE	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
CH2_k127_9372544_6	1163617.SCD_n02652	6.306e-73	248.0	COG1959@1|root,COG1959@2|Bacteria,1RE3F@1224|Proteobacteria,2VRIR@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
CH2_k127_9372544_8	1144342.PMI40_02712	1.661e-68	237.0	COG1999@1|root,COG1999@2|Bacteria,1RHJ8@1224|Proteobacteria,2VR3M@28216|Betaproteobacteria,473BA@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Involved in biogenesis of respiratory and photosynthetic systems	senC	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
CH2_k127_9372544_5	1163617.SCD_n02650	1.524e-81	278.0	COG0664@1|root,COG0664@2|Bacteria,1MVGE@1224|Proteobacteria,2VH04@28216|Betaproteobacteria	28216|Betaproteobacteria	K	CRP FNR family	fnr	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CH2_k127_9372544_0	582744.Msip34_2142	3.641e-276	853.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,2VIWB@28216|Betaproteobacteria,2KKTV@206350|Nitrosomonadales	206350|Nitrosomonadales	C	TIGRFAM cytochrome c oxidase, cbb3-type, subunit I	-	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
CH2_k127_9372544_4	265072.Mfla_0630	1.248e-119	388.0	COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,2VIJ2@28216|Betaproteobacteria,2KMM8@206350|Nitrosomonadales	206350|Nitrosomonadales	C	PFAM cytochrome C oxidase mono-heme subunit FixO	-	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixO
CH2_k127_9372544_9	1236959.BAMT01000004_gene800	5.198e-20	90.0	2EHQ5@1|root,33BFX@2|Bacteria,1NJW1@1224|Proteobacteria,2VXSI@28216|Betaproteobacteria,2KP0N@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Cbb3-type cytochrome oxidase component FixQ	-	-	-	-	-	-	-	-	-	-	-	-	FixQ
CH2_k127_9372544_3	1163617.SCD_n02646	3.424e-144	462.0	COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,2VHGS@28216|Betaproteobacteria	28216|Betaproteobacteria	C	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N,OmpA
CH2_k127_9372544_2	1163617.SCD_n02645	7.361e-240	749.0	COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,2VHRH@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome c oxidase accessory protein ccog	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
CH2_k127_9372544_7	1163617.SCD_n02644	3.074e-70	246.0	COG5456@1|root,COG5456@2|Bacteria,1N6AR@1224|Proteobacteria,2VU84@28216|Betaproteobacteria	28216|Betaproteobacteria	P	FixH	-	-	-	-	-	-	-	-	-	-	-	-	FixH
CH2_k127_9372544_1	1163617.SCD_n02643	2.169e-259	811.0	COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria,1MU08@1224|Proteobacteria,2VJSM@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Heavy metal translocating P-type atpase	ccoI	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
CH2_k127_9382089_0	1485544.JQKP01000001_gene922	1.155e-239	748.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,2VI3N@28216|Betaproteobacteria,44VGZ@713636|Nitrosomonadales	28216|Betaproteobacteria	J	PFAM RNA-binding protein AU-1 Ribonuclease E G	cafA	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
CH2_k127_9382089_1	1163617.SCD_n00061	6.403e-69	239.0	COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,2VQC3@28216|Betaproteobacteria	28216|Betaproteobacteria	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
CH2_k127_9382089_3	1121004.ATVC01000063_gene1631	1.56e-34	133.0	COG1576@1|root,COG1576@2|Bacteria,1R9Z2@1224|Proteobacteria,2VQ2M@28216|Betaproteobacteria,2KR0M@206351|Neisseriales	206351|Neisseriales	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
CH2_k127_9393970_0	1123392.AQWL01000003_gene260	9.62e-191	615.0	COG4870@1|root,COG4870@2|Bacteria,1MV6S@1224|Proteobacteria,2VN18@28216|Betaproteobacteria	28216|Betaproteobacteria	O	cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C1
CH2_k127_9393970_3	580332.Slit_1119	5.496e-133	436.0	COG3278@1|root,COG3278@2|Bacteria,1P8T0@1224|Proteobacteria,2VNAW@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Belongs to the heme-copper respiratory oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_9393970_6	580332.Slit_1118	9.952e-24	102.0	COG0425@1|root,COG0425@2|Bacteria,1QU8C@1224|Proteobacteria,2WGIR@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Uncharacterized conserved protein (DUF2249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2249
CH2_k127_9393970_5	580332.Slit_1117	5.271e-39	151.0	COG3945@1|root,COG3945@2|Bacteria,1N383@1224|Proteobacteria,2VUXI@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
CH2_k127_9393970_4	1049564.TevJSym_ag00760	3.402e-46	169.0	COG2920@1|root,COG2920@2|Bacteria,1MWK9@1224|Proteobacteria,1RYE1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	TIGRFAM sulfur relay protein, TusE DsrC DsvC family	-	-	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
CH2_k127_9393970_2	1163617.SCD_n00436	2.299e-141	461.0	COG3213@1|root,COG3213@2|Bacteria,1MUJK@1224|Proteobacteria,2VJ75@28216|Betaproteobacteria	28216|Betaproteobacteria	P	PFAM NnrS family protein	-	-	-	ko:K07234	-	-	-	-	ko00000	-	-	-	NnrS
CH2_k127_9393970_1	1163617.SCD_n00385	1.299e-189	596.0	COG1328@1|root,COG1328@2|Bacteria,1MWMS@1224|Proteobacteria,2VJYM@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Ribonucleoside-triphosphate reductase	nrdD	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,NRDD
CH2_k127_9408304_6	1149133.ppKF707_3647	2.383e-64	221.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,1RQ7S@1236|Gammaproteobacteria,1YDDM@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	E	DegT/DnrJ/EryC1/StrS aminotransferase family	vioA	-	2.6.1.33	ko:K20429	-	-	R02773	RC00006,RC00781	ko00000,ko01000	-	-	-	DegT_DnrJ_EryC1
CH2_k127_9408304_14	324925.Ppha_1588	1.051e-21	96.0	COG2445@1|root,COG2445@2|Bacteria	2|Bacteria	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
CH2_k127_9408304_15	1123228.AUIH01000020_gene3351	9.212e-05	50.0	COG2445@1|root,COG2445@2|Bacteria,1RD67@1224|Proteobacteria,1SAKV@1236|Gammaproteobacteria,1XQ5C@135619|Oceanospirillales	1236|Gammaproteobacteria	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
CH2_k127_9408304_9	686340.Metal_2798	1.387e-43	162.0	COG1669@1|root,COG1669@2|Bacteria,1N4HR@1224|Proteobacteria,1SD6W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
CH2_k127_9408304_13	1123368.AUIS01000003_gene1673	2.587e-31	127.0	COG1708@1|root,COG1708@2|Bacteria,1N7SN@1224|Proteobacteria,1T99G@1236|Gammaproteobacteria,2NE28@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
CH2_k127_9408304_0	1163617.SCD_n02408	3.477e-302	935.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,2VJTS@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Belongs to the 5'-nucleotidase family	soxB	-	3.1.3.5,3.6.1.45	ko:K11751,ko:K17224	ko00230,ko00240,ko00760,ko00920,ko01100,ko01110,ko01120,map00230,map00240,map00760,map00920,map01100,map01110,map01120	M00595	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346,R10151	RC00017,RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	-	-	-	5_nucleotid_C
CH2_k127_9408304_3	292415.Tbd_0564	5.669e-112	367.0	COG3258@1|root,COG3258@2|Bacteria,1MXB0@1224|Proteobacteria,2VJ8Q@28216|Betaproteobacteria,1KSVE@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Thiosulfate-oxidizing multienzyme system protein SoxA	-	-	-	ko:K17222	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	-
CH2_k127_9408304_11	1123392.AQWL01000004_gene2733	1.635e-36	140.0	COG5501@1|root,COG5501@2|Bacteria,1N097@1224|Proteobacteria,2VU95@28216|Betaproteobacteria,1KT6D@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Sulphur oxidation protein SoxZ	-	-	-	ko:K17227	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxZ
CH2_k127_9408304_7	1123392.AQWL01000004_gene2625	9.478e-53	190.0	COG5501@1|root,COG5501@2|Bacteria,1RH4J@1224|Proteobacteria,2VT8I@28216|Betaproteobacteria	28216|Betaproteobacteria	S	sulfur oxidation protein SoxY	soxY	-	-	ko:K17226	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxY
CH2_k127_9408304_10	292415.Tbd_0917	4.244e-39	149.0	COG2010@1|root,COG2010@2|Bacteria,1N91W@1224|Proteobacteria,2WC94@28216|Betaproteobacteria,1KT9N@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	ko:K17223	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	Cytochrome_CBB3
CH2_k127_9408304_1	1163617.SCD_n00796	2.236e-176	565.0	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,2VHAY@28216|Betaproteobacteria	28216|Betaproteobacteria	S	peptidase m48, ste24p	yggG_1	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TPR_19
CH2_k127_9408304_5	1163617.SCD_n00797	7.751e-69	240.0	COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,2VR7B@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
CH2_k127_9408304_2	1163617.SCD_n01896	5.67e-168	542.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,2VJIC@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
CH2_k127_9408304_4	395494.Galf_0662	6.604e-87	291.0	COG0811@1|root,COG0811@2|Bacteria,1QNJ1@1224|Proteobacteria,2VITY@28216|Betaproteobacteria,44V9Z@713636|Nitrosomonadales	28216|Betaproteobacteria	U	PFAM MotA TolQ ExbB proton channel	exbB2	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
CH2_k127_9408304_8	1163617.SCD_n01894	3.251e-46	171.0	COG0848@1|root,COG0848@2|Bacteria,1N0ZA@1224|Proteobacteria,2VUF4@28216|Betaproteobacteria	28216|Betaproteobacteria	U	Biopolymer transport protein	exbD2	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
CH2_k127_9408304_12	666681.M301_0664	6.627e-34	134.0	COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,2VHPG@28216|Betaproteobacteria,2KKX0@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
CH2_k127_943169_0	1163617.SCD_n01976	7.577e-137	439.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,2VJ6H@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
CH2_k127_943169_1	666681.M301_0436	3.897e-65	231.0	29TFP@1|root,30ENV@2|Bacteria,1RG86@1224|Proteobacteria,2VS6R@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_943169_2	1163617.SCD_n01922	2.118e-50	182.0	COG1047@1|root,COG1047@2|Bacteria,1N0ZF@1224|Proteobacteria,2W2PN@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Peptidyl-prolyl cis-trans	-	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
CH2_k127_9460632_0	1163617.SCD_n01668	1.511e-194	620.0	COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,2VJMF@28216|Betaproteobacteria	28216|Betaproteobacteria	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
CH2_k127_9460632_3	1163617.SCD_n01669	2.534e-64	222.0	COG1848@1|root,COG1848@2|Bacteria,1RA9A@1224|Proteobacteria,2VX83@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PIN domain	-	-	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
CH2_k127_9460632_5	1163617.SCD_n01670	8.366e-34	131.0	COG4118@1|root,COG4118@2|Bacteria,1N187@1224|Proteobacteria	1224|Proteobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
CH2_k127_9460632_2	1163617.SCD_n01671	5.179e-77	261.0	COG0780@1|root,COG0780@2|Bacteria,1MW0M@1224|Proteobacteria,2VINU@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K06879,ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF,QueF_N
CH2_k127_9460632_1	1123393.KB891326_gene237	4.649e-163	523.0	COG1070@1|root,COG1070@2|Bacteria,1MW4A@1224|Proteobacteria,2VI4Z@28216|Betaproteobacteria,1KSW2@119069|Hydrogenophilales	119069|Hydrogenophilales	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
CH2_k127_9460632_4	1163617.SCD_n01673	1.115e-41	162.0	2EJ60@1|root,33CX7@2|Bacteria,1NJ7I@1224|Proteobacteria	1224|Proteobacteria	S	Atypical PilZ domain, cyclic di-GMP receptor	-	-	-	-	-	-	-	-	-	-	-	-	PilZ_2
CH2_k127_9541708_1	1167006.UWK_02555	1.427e-104	342.0	COG4239@1|root,COG4239@2|Bacteria,1MUM5@1224|Proteobacteria,42P23@68525|delta/epsilon subdivisions,2WK75@28221|Deltaproteobacteria,2MIZ4@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K13895	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	BPD_transp_1,OppC_N
CH2_k127_9541708_0	395493.BegalDRAFT_3540	2.93e-214	677.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,1RMEI@1236|Gammaproteobacteria,45ZN9@72273|Thiotrichales	72273|Thiotrichales	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
CH2_k127_9541708_2	1288494.EBAPG3_18020	5.028e-72	246.0	COG3103@1|root,COG3103@2|Bacteria,1MVX1@1224|Proteobacteria,2VKXR@28216|Betaproteobacteria,372NR@32003|Nitrosomonadales	28216|Betaproteobacteria	T	Sh3 type 3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_9621738_3	1163617.SCD_n01893	1.306e-86	293.0	COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,2VHPG@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
CH2_k127_9621738_2	1163617.SCD_n01891	2.284e-106	351.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,2VINM@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
CH2_k127_9621738_1	292415.Tbd_1504	1.707e-122	395.0	COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,2VH1C@28216|Betaproteobacteria,1KREU@119069|Hydrogenophilales	119069|Hydrogenophilales	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
CH2_k127_9621738_4	1163617.SCD_n01889	2.599e-40	152.0	2E7PJ@1|root,33255@2|Bacteria,1NANJ@1224|Proteobacteria,2W4P4@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_9621738_0	292415.Tbd_1502	2.287e-157	497.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,2VK7J@28216|Betaproteobacteria,1KRDF@119069|Hydrogenophilales	119069|Hydrogenophilales	G	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
CH2_k127_9632744_1	1266925.JHVX01000020_gene1778	5.59e-92	304.0	COG1943@1|root,COG1943@2|Bacteria,1RCWW@1224|Proteobacteria,2VSPX@28216|Betaproteobacteria,3747T@32003|Nitrosomonadales	28216|Betaproteobacteria	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
CH2_k127_9632744_0	1304883.KI912532_gene2112	1.783e-201	636.0	COG1362@1|root,COG1362@2|Bacteria,1NT1D@1224|Proteobacteria,2VMH5@28216|Betaproteobacteria	28216|Betaproteobacteria	E	PFAM Peptidase M18, aminopeptidase I	-	-	3.4.11.21	ko:K01267	-	-	-	-	ko00000,ko01000,ko01002,ko04131	-	-	-	Peptidase_M18
CH2_k127_9632744_2	292415.Tbd_0146	9.883e-71	248.0	COG3245@1|root,COG3245@2|Bacteria,1MZBZ@1224|Proteobacteria,2VMBB@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CH2_k127_9632744_3	1288494.EBAPG3_2480	1.365e-54	198.0	COG3536@1|root,COG3536@2|Bacteria,1MZ5M@1224|Proteobacteria,2VR9K@28216|Betaproteobacteria,3734V@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF971
CH2_k127_9657858_2	292415.Tbd_2138	2.835e-159	503.0	COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,2VJ29@28216|Betaproteobacteria,1KS8H@119069|Hydrogenophilales	119069|Hydrogenophilales	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	-	-	5.4.2.2,5.4.2.8	ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
CH2_k127_9657858_8	497321.C664_04777	4.242e-49	197.0	COG3170@1|root,COG3170@2|Bacteria,1RE27@1224|Proteobacteria,2VRNH@28216|Betaproteobacteria,2KW0V@206389|Rhodocyclales	206389|Rhodocyclales	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_9657858_4	269799.Gmet_3025	4.637e-114	388.0	COG1315@1|root,COG1315@2|Bacteria,1R40D@1224|Proteobacteria,42TMJ@68525|delta/epsilon subdivisions,2WPZ3@28221|Deltaproteobacteria,43VJY@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Flagellar Assembly Protein A	-	-	-	ko:K09749	-	-	-	-	ko00000	-	-	-	FapA
CH2_k127_9657858_6	1163617.SCD_n02414	5.348e-96	318.0	COG0500@1|root,COG0500@2|Bacteria,1RDHE@1224|Proteobacteria,2VQIP@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Protein of unknown function (DUF938)	-	-	-	-	-	-	-	-	-	-	-	-	DUF938
CH2_k127_9657858_5	1163617.SCD_n01299	1.116e-104	350.0	COG0457@1|root,COG0457@2|Bacteria,1NKN8@1224|Proteobacteria	1224|Proteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
CH2_k127_9657858_9	1163617.SCD_n02803	2.644e-48	177.0	COG1974@1|root,COG1974@2|Bacteria,1QUQ8@1224|Proteobacteria,2VWS0@28216|Betaproteobacteria	28216|Betaproteobacteria	KT	Peptidase S24-like	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S24
CH2_k127_9657858_7	316067.Geob_0726	1.115e-50	189.0	COG2067@1|root,COG2067@2|Bacteria,1N1F4@1224|Proteobacteria,42ZP2@68525|delta/epsilon subdivisions,2WUUM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Putative MetA-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
CH2_k127_9657858_1	1163617.SCD_n01959	2.735e-180	566.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,2VHR7@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
CH2_k127_9657858_10	1288494.EBAPG3_13600	2.64e-25	106.0	COG4391@1|root,COG4391@2|Bacteria,1N7QM@1224|Proteobacteria,2VVV6@28216|Betaproteobacteria,373FJ@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Zinc-finger domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-CHCC
CH2_k127_9657858_3	395494.Galf_0514	2.193e-131	428.0	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,2VHHX@28216|Betaproteobacteria,44UZE@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	rfaF	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
CH2_k127_9657858_0	1163617.SCD_n00856	3.819e-193	608.0	COG0260@1|root,COG0260@2|Bacteria,1MXP6@1224|Proteobacteria,2VJ0K@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Belongs to the peptidase M17 family	-	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17
CH2_k127_9697510_3	1123392.AQWL01000008_gene1146	1.987e-215	675.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,2VHCZ@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07239	-	-	-	-	ko00000	2.A.6.1	-	-	ACR_tran
CH2_k127_9697510_5	1123392.AQWL01000008_gene1147	8.042e-41	154.0	2D626@1|root,31JSA@2|Bacteria,1RJ4G@1224|Proteobacteria,2VTSC@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_9697510_1	1163617.SCD_n01140	3.802e-241	747.0	COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,2VNWB@28216|Betaproteobacteria	28216|Betaproteobacteria	E	PFAM aminotransferase class V	-	-	2.6.1.44,2.6.1.45,2.6.1.51	ko:K00830	ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	M00346,M00532	R00369,R00372,R00585,R00588	RC00006,RC00008,RC00018	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
CH2_k127_9697510_2	1163617.SCD_n01139	4.832e-219	684.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,2VISA@28216|Betaproteobacteria	28216|Betaproteobacteria	C	glycolate oxidase iron-sulfur subunit	glcF	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_7,Fer4_8
CH2_k127_9697510_4	1163617.SCD_n01138	3.199e-173	548.0	COG0277@1|root,COG0277@2|Bacteria,1MVYV@1224|Proteobacteria,2VHUQ@28216|Betaproteobacteria	28216|Betaproteobacteria	C	PFAM FAD linked oxidase domain protein	glcE	-	1.1.3.15	ko:K00104,ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
CH2_k127_9697510_0	1163617.SCD_n01137	1.049e-291	899.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2VH8M@28216|Betaproteobacteria	28216|Betaproteobacteria	C	PFAM FAD linked oxidase domain protein	glcD	-	1.1.2.4,1.1.3.15,1.1.5.12	ko:K00102,ko:K00104,ko:K03777	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	-	R00197,R00475,R00704,R11591	RC00042,RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
CH2_k127_9697510_6	1123368.AUIS01000005_gene488	5.418e-12	66.0	COG1414@1|root,COG1414@2|Bacteria,1MUNW@1224|Proteobacteria,1SB98@1236|Gammaproteobacteria,2NCIT@225057|Acidithiobacillales	225057|Acidithiobacillales	K	Transcriptional regulator IclR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
CH2_k127_9715437_1	1223521.BBJX01000008_gene1280	3.093e-29	119.0	COG0457@1|root,COG0745@1|root,COG0457@2|Bacteria,COG0745@2|Bacteria,1NNCT@1224|Proteobacteria,2VK0Z@28216|Betaproteobacteria,4ABC4@80864|Comamonadaceae	28216|Betaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,TPR_16,TPR_19,TPR_4,TPR_8
CH2_k127_9715437_0	1163617.SCD_n01679	1.414e-178	566.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2VHBY@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
CH2_k127_9735894_0	748280.NH8B_4057	7.609e-95	315.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,2VHHU@28216|Betaproteobacteria,2KQ6Z@206351|Neisseriales	206351|Neisseriales	O	Collagenase	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32
CH2_k127_9735894_2	580332.Slit_2773	5.738e-31	123.0	COG2345@1|root,COG2345@2|Bacteria,1N9W3@1224|Proteobacteria,2VWG0@28216|Betaproteobacteria,44WNR@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_9735894_1	1122603.ATVI01000005_gene3268	2.79e-84	292.0	COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,1RMTC@1236|Gammaproteobacteria,1X336@135614|Xanthomonadales	135614|Xanthomonadales	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
CH2_k127_9762105_0	1121439.dsat_1293	1.262e-92	326.0	COG0367@1|root,COG0367@2|Bacteria	2|Bacteria	E	asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase
CH2_k127_9774424_0	1049564.TevJSym_ac00600	6.051e-213	676.0	COG1271@1|root,COG1271@2|Bacteria	2|Bacteria	C	aerobic electron transport chain	-	-	1.10.3.14	ko:K00425,ko:K08738	ko00190,ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00190,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00153,M00595	R10151,R11325	RC00061,RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	3.D.4.3,3.D.4.6	-	-	Cyt_bd_oxida_I,Cytochrome_CBB3
CH2_k127_9774424_3	1049564.TevJSym_ac00590	9.191e-58	211.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	ko:K02305	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002	3.D.4.10	-	-	Cytochrom_C,GSDH
CH2_k127_9774424_2	1049564.TevJSym_ac00580	1.233e-73	256.0	COG2010@1|root,COG2010@2|Bacteria,1R28S@1224|Proteobacteria,1T5JD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CH2_k127_9774424_1	247490.KSU1_B0265	6.988e-101	347.0	COG2010@1|root,COG2010@2|Bacteria,2IZN4@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,EB_dh
CH2_k127_9774424_5	1236959.BAMT01000011_gene3146	2.011e-40	150.0	COG0227@1|root,COG0227@2|Bacteria,1MZ57@1224|Proteobacteria,2VU1B@28216|Betaproteobacteria,2KN2K@206350|Nitrosomonadales	206350|Nitrosomonadales	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
CH2_k127_9774424_6	1120999.JONM01000002_gene946	5.276e-22	95.0	COG0267@1|root,COG0267@2|Bacteria,1N6QV@1224|Proteobacteria,2VVW8@28216|Betaproteobacteria,2KRX9@206351|Neisseriales	206351|Neisseriales	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
CH2_k127_9774424_4	398525.KB900701_gene7301	4.193e-55	201.0	COG4278@1|root,COG4278@2|Bacteria,1RBTS@1224|Proteobacteria,2U33M@28211|Alphaproteobacteria,3JWV5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	H	phenylacetate-CoA ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_9838803_0	1123392.AQWL01000022_gene2175	7.776e-197	619.0	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,2VHF7@28216|Betaproteobacteria,1KSWW@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
CH2_k127_9838803_2	292415.Tbd_0458	2.05e-162	522.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2VHBS@28216|Betaproteobacteria,1KRJS@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CH2_k127_9838803_3	1123392.AQWL01000022_gene2177	1.108e-134	438.0	COG2377@1|root,COG2377@2|Bacteria,1MV4E@1224|Proteobacteria,2VHCE@28216|Betaproteobacteria,1KS3X@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Anhydro-N-acetylmuramic acid kinase	-	-	-	-	-	-	-	-	-	-	-	-	AnmK
CH2_k127_9838803_7	2340.JV46_12270	1.774e-74	264.0	COG0189@1|root,COG0189@2|Bacteria,1NNP5@1224|Proteobacteria,1RRUB@1236|Gammaproteobacteria,1JB2N@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	HJ	ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	TauD
CH2_k127_9838803_10	81824.XP_001743362.1	5.857e-34	143.0	KOG1584@1|root,KOG1584@2759|Eukaryota,38BJI@33154|Opisthokonta	33154|Opisthokonta	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1
CH2_k127_9838803_6	234267.Acid_7941	2.193e-77	277.0	COG0076@1|root,COG0076@2|Bacteria,3Y3S7@57723|Acidobacteria	57723|Acidobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
CH2_k127_9838803_4	69781.S7Z901	2.296e-105	350.0	KOG1584@1|root,KOG1584@2759|Eukaryota,394HT@33154|Opisthokonta	33154|Opisthokonta	S	Belongs to the sulfotransferase 1 family	-	GO:0003674,GO:0003824,GO:0004062,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008146,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016782,GO:0034930,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0051923	2.8.2.1,2.8.2.3,2.8.2.4	ko:K01014,ko:K01016,ko:K01025,ko:K16949	ko00140,ko05204,map00140,map05204	-	R01242,R01861,R02350	RC00007,RC00128,RC00610	ko00000,ko00001,ko01000	-	-	-	Sulfotransfer_1
CH2_k127_9838803_9	292415.Tbd_0456	1.912e-60	210.0	COG0316@1|root,COG0316@2|Bacteria,1RHCW@1224|Proteobacteria,2VR2M@28216|Betaproteobacteria,1KRPV@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Iron-sulphur cluster biosynthesis	erpA	-	-	ko:K15724	-	-	-	-	ko00000	-	-	-	Fe-S_biosyn
CH2_k127_9838803_1	1123393.KB891318_gene2184	5.866e-186	587.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,2VJD7@28216|Betaproteobacteria,1KRDK@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
CH2_k127_9838803_8	292415.Tbd_0454	1.04e-63	220.0	COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,2VR5R@28216|Betaproteobacteria,1KRMF@119069|Hydrogenophilales	119069|Hydrogenophilales	J	Ribosomal protein S9/S16	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
CH2_k127_9838803_5	305700.B447_07317	2.964e-78	263.0	COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,2VQ07@28216|Betaproteobacteria,2KW9N@206389|Rhodocyclales	206389|Rhodocyclales	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
CH2_k127_9838803_11	472759.Nhal_0862	3.172e-06	49.0	COG1765@1|root,COG1765@2|Bacteria,1RCZW@1224|Proteobacteria,1S3XF@1236|Gammaproteobacteria,1WY24@135613|Chromatiales	135613|Chromatiales	O	redox protein, regulator of disulfide bond formation	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
CH2_k127_9861184_0	1163617.SCD_n01127	4.11e-241	749.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2VH4Z@28216|Betaproteobacteria	28216|Betaproteobacteria	E	PFAM aminotransferase class I and II	alaA	-	2.6.1.2,2.6.1.66	ko:K14260	ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230	-	R00258,R01215	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CH2_k127_9861184_3	1163617.SCD_n01126	4.616e-43	163.0	COG3737@1|root,COG3737@2|Bacteria,1N083@1224|Proteobacteria,2VUF2@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF498/DUF598)	-	-	-	-	-	-	-	-	-	-	-	-	DUF498
CH2_k127_9861184_2	1163617.SCD_n01123	2.425e-99	328.0	COG1011@1|root,COG1011@2|Bacteria,1NH15@1224|Proteobacteria,2VZS8@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	3.1.3.5	ko:K20881	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
CH2_k127_9861184_1	926560.KE387023_gene2722	8.209e-108	366.0	COG5002@1|root,COG5002@2|Bacteria,1WNHC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_8,PAS_9,Response_reg
CH2_k127_9863261_12	1163617.SCD_n01467	3.677e-08	55.0	COG0745@1|root,COG0745@2|Bacteria,1RETP@1224|Proteobacteria,2WGYY@28216|Betaproteobacteria	28216|Betaproteobacteria	KT	Response regulator receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
CH2_k127_9863261_8	1266925.JHVX01000015_gene223	6.557e-54	198.0	COG1502@1|root,COG1502@2|Bacteria,1RG6H@1224|Proteobacteria,2VTMJ@28216|Betaproteobacteria,37437@32003|Nitrosomonadales	28216|Betaproteobacteria	I	PLD-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
CH2_k127_9863261_2	1163617.SCD_n00753	1.213e-157	507.0	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,2VJTH@28216|Betaproteobacteria	28216|Betaproteobacteria	M	mechanosensitive ion channel	aefA	-	-	-	-	-	-	-	-	-	-	-	MS_channel
CH2_k127_9863261_1	335283.Neut_0779	3.059e-176	560.0	COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,2VHRS@28216|Betaproteobacteria,37215@32003|Nitrosomonadales	28216|Betaproteobacteria	I	fatty acid desaturase	ole1	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	DDE_Tnp_ISL3,FA_desaturase
CH2_k127_9863261_10	887898.HMPREF0551_0363	1.515e-23	100.0	COG0267@1|root,COG0267@2|Bacteria,1N6QV@1224|Proteobacteria,2VVW8@28216|Betaproteobacteria,1KA4N@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
CH2_k127_9863261_9	395494.Galf_2279	1.308e-39	147.0	COG0227@1|root,COG0227@2|Bacteria,1MZ57@1224|Proteobacteria,2VU1B@28216|Betaproteobacteria,44W1P@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
CH2_k127_9863261_5	1163617.SCD_n00750	2.121e-99	329.0	COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,2VKTW@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
CH2_k127_9863261_0	1163617.SCD_n00749	6.173e-197	621.0	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,2VI4X@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
CH2_k127_9863261_7	305700.B447_07197	7.739e-73	247.0	COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,2VQ5I@28216|Betaproteobacteria,2KWAF@206389|Rhodocyclales	206389|Rhodocyclales	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
CH2_k127_9863261_4	292415.Tbd_2585	2.956e-104	355.0	COG2199@1|root,COG3706@2|Bacteria,1MX83@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	-	-	2.7.7.65	ko:K20955	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF,dCache_1
CH2_k127_9863261_11	1123392.AQWL01000002_gene1723	7.73e-15	77.0	2C3ZD@1|root,306IY@2|Bacteria,1PWVK@1224|Proteobacteria,2WCE9@28216|Betaproteobacteria,1KTI4@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_9863261_6	1163617.SCD_n01092	2.454e-89	297.0	COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,2VS2C@28216|Betaproteobacteria	28216|Betaproteobacteria	KT	Belongs to the peptidase S24 family	-	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	Peptidase_S24
CH2_k127_9863261_13	351348.Maqu_3664	5.385e-05	54.0	COG2199@1|root,COG3221@1|root,COG5002@1|root,COG2199@2|Bacteria,COG3221@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1T1JE@1236|Gammaproteobacteria,469WH@72275|Alteromonadaceae	1236|Gammaproteobacteria	PT	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CHASE,GAF_2,GGDEF,HAMP,HATPase_c,HTH_18,HisKA,Hpt,MASE1,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Phosphonate-bd,Reg_prop,Response_reg,TarH,Y_Y_Y
CH2_k127_9863261_3	292415.Tbd_1650	5.23e-106	349.0	COG0607@1|root,COG0607@2|Bacteria,1REGB@1224|Proteobacteria,2WFKS@28216|Betaproteobacteria,1KSFA@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CH2_k127_9872988_0	1123368.AUIS01000005_gene487	0.0	1080.0	COG3957@1|root,COG3957@2|Bacteria,1MVSE@1224|Proteobacteria,1RYC8@1236|Gammaproteobacteria,2NC3Q@225057|Acidithiobacillales	225057|Acidithiobacillales	G	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase	-	-	-	-	-	-	-	-	-	-	-	-	XFP,XFP_N
CH2_k127_9872988_1	314345.SPV1_08461	9.207e-204	643.0	COG3395@1|root,COG3395@2|Bacteria	2|Bacteria	S	kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1357_C,DUF1537
CH2_k127_9916062_11	1101195.Meth11DRAFT_1764	2.024e-35	143.0	COG3134@1|root,COG3134@2|Bacteria,1MVWD@1224|Proteobacteria,2VTZ2@28216|Betaproteobacteria,2KMT7@206350|Nitrosomonadales	206350|Nitrosomonadales	S	PFAM 17 kDa surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Rick_17kDa_Anti
CH2_k127_9916062_1	1163617.SCD_n01062	3.95e-227	707.0	COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,2VINP@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Belongs to the aspartokinase family	lysC	GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
CH2_k127_9916062_9	1163617.SCD_n01061	2.192e-38	145.0	COG2944@1|root,COG2944@2|Bacteria,1N48U@1224|Proteobacteria,2VUHQ@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
CH2_k127_9916062_4	1163617.SCD_n01060	4.334e-118	385.0	COG0731@1|root,COG0731@2|Bacteria,1QG36@1224|Proteobacteria,2VK7Z@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
CH2_k127_9916062_6	395494.Galf_1826	1.265e-70	241.0	COG0720@1|root,COG0720@2|Bacteria,1RETG@1224|Proteobacteria,2VRBN@28216|Betaproteobacteria,44VRF@713636|Nitrosomonadales	28216|Betaproteobacteria	H	6-pyruvoyl tetrahydropterin synthase	queD	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
CH2_k127_9916062_10	395494.Galf_2163	3.02e-37	145.0	COG0589@1|root,COG0589@2|Bacteria,1N02E@1224|Proteobacteria,2VU60@28216|Betaproteobacteria,44W1F@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CH2_k127_9916062_5	1163617.SCD_n02047	7.668e-106	351.0	COG1270@1|root,COG1270@2|Bacteria,1MWCK@1224|Proteobacteria,2VH7X@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	cobD	-	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
CH2_k127_9916062_7	1163617.SCD_n02419	1.886e-66	233.0	COG3064@1|root,COG3064@2|Bacteria,1P2CR@1224|Proteobacteria	1224|Proteobacteria	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CH2_k127_9916062_0	1163617.SCD_n00297	0.0	1693.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHZQ@28216|Betaproteobacteria	28216|Betaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K18303	-	M00642	-	-	ko00000,ko00002,ko01504,ko02000	2.A.6.2.17	-	-	ACR_tran
CH2_k127_9916062_3	1163617.SCD_n00298	3.826e-141	456.0	COG0845@1|root,COG0845@2|Bacteria,1NJDF@1224|Proteobacteria,2VIS6@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
CH2_k127_9916062_2	1163617.SCD_n02537	1.361e-163	525.0	COG2821@1|root,COG2821@2|Bacteria,1MXD4@1224|Proteobacteria,2VHBF@28216|Betaproteobacteria	28216|Betaproteobacteria	M	membrane-bound lytic murein transglycosylase	mltA	-	-	ko:K08304	-	-	-	-	ko00000,ko01000,ko01011	-	GH102	-	3D,MltA
CH2_k127_9916062_12	1173023.KE650771_gene2706	9.049e-27	111.0	COG2442@1|root,COG2442@2|Bacteria,1G89F@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
CH2_k127_9916062_8	388467.A19Y_0945	1.254e-40	153.0	COG4634@1|root,COG4634@2|Bacteria,1G6P5@1117|Cyanobacteria,1HBE2@1150|Oscillatoriales	1117|Cyanobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
## 1859 queries scanned
## Total time (seconds): 2.4190640449523926
## Rate: 768.48 q/s