## Sat Dec 13 06:46:57 2025
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/qs/new/CH3_bin.43.fa -m mmseqs --itype genome -o CH3_bin.43 --output_dir /data/result/bins/wyx/egg/CH3_bin.43 --cpu 32
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
CH3_k127_10013245_9	28564.XP_002340131.1	3.032e-54	206.0	KOG4155@1|root,KOG4155@2759|Eukaryota,3AG0Y@33154|Opisthokonta,3Q4RG@4751|Fungi,3RN16@4890|Ascomycota,20UKC@147545|Eurotiomycetes,3SE9V@5042|Eurotiales	4751|Fungi	S	Encoded by	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,NACHT,WD40
CH3_k127_10013245_15	794903.OPIT5_29740	8.991e-11	74.0	COG2165@1|root,COG2165@2|Bacteria,46Y7T@74201|Verrucomicrobia,3K92V@414999|Opitutae	414999|Opitutae	NU	Protein of unknown function (DUF1559)	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_10
CH3_k127_10013245_8	1192034.CAP_0893	5.613e-60	235.0	COG3509@1|root,COG3509@2|Bacteria,1N6M6@1224|Proteobacteria,42U8Z@68525|delta/epsilon subdivisions,2WQQT@28221|Deltaproteobacteria,2YV47@29|Myxococcales	28221|Deltaproteobacteria	Q	Esterase PHB depolymerase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Esterase_phd
CH3_k127_10013245_11	575540.Isop_1614	5.381e-46	190.0	COG2373@1|root,COG2373@2|Bacteria,2IZBV@203682|Planctomycetes	203682|Planctomycetes	Q	aggregation factor core protein MAFp3, isoform C	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,FG-GAP_2
CH3_k127_10013245_6	497964.CfE428DRAFT_4864	4.548e-66	234.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_10013245_12	519989.ECTPHS_02009	6.456e-45	170.0	COG0778@1|root,COG0778@2|Bacteria	2|Bacteria	C	coenzyme F420-1:gamma-L-glutamate ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase,TM1586_NiRdase
CH3_k127_10013245_0	1123242.JH636435_gene1092	1.14e-178	570.0	COG0673@1|root,COG0673@2|Bacteria,2IX39@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CH3_k127_10013245_13	278957.ABEA03000093_gene4635	7.387e-20	94.0	arCOG03330@1|root,2Z82Q@2|Bacteria	2|Bacteria	S	PFAM Methanol-cobalamin methyltransferase B subunit	-	-	2.1.1.90	ko:K04480	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00356	R04384,R09098	RC00035,RC01144,RC01145,RC02440	ko00000,ko00001,ko00002,ko01000	-	-	-	MtaB
CH3_k127_10013245_4	234267.Acid_6968	1.289e-76	263.0	COG5012@1|root,COG5012@2|Bacteria,3Y88D@57723|Acidobacteria	57723|Acidobacteria	S	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
CH3_k127_10013245_5	903818.KI912269_gene107	3.013e-66	239.0	COG0646@1|root,COG0646@2|Bacteria,3Y7SY@57723|Acidobacteria	57723|Acidobacteria	E	Homocysteine S-methyltransferase	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	S-methyl_trans
CH3_k127_10013245_3	697281.Mahau_2725	1.873e-88	303.0	COG0407@1|root,COG0407@2|Bacteria,1TR8Q@1239|Firmicutes,24B2U@186801|Clostridia,42IQ4@68295|Thermoanaerobacterales	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	2.1.1.246,4.1.1.37	ko:K01599,ko:K14080	ko00680,ko00860,ko01100,ko01110,ko01120,ko01200,map00680,map00860,map01100,map01110,map01120,map01200	M00121,M00356	R03197,R04972,R09098,R10000	RC00035,RC00872,RC01144,RC02440	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
CH3_k127_10013245_7	349741.Amuc_1932	4.271e-61	228.0	COG0251@1|root,COG0251@2|Bacteria,46V5Y@74201|Verrucomicrobia,2IW47@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
CH3_k127_10013245_2	880526.KE386488_gene1576	1.359e-88	324.0	COG0823@1|root,COG0823@2|Bacteria,4NIGD@976|Bacteroidetes,2G2P7@200643|Bacteroidia	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_10013245_1	1304885.AUEY01000104_gene2548	1.416e-108	370.0	COG0702@1|root,COG0702@2|Bacteria,1Q438@1224|Proteobacteria,439WM@68525|delta/epsilon subdivisions,2X29K@28221|Deltaproteobacteria,2MPBK@213118|Desulfobacterales	28221|Deltaproteobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
CH3_k127_10013245_10	742725.HMPREF9450_01261	1.055e-49	182.0	COG2871@1|root,COG3894@1|root,COG2871@2|Bacteria,COG3894@2|Bacteria,4PAMG@976|Bacteroidetes,2FXAJ@200643|Bacteroidia	976|Bacteroidetes	C	Domain of unknown function (DUF4445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
CH3_k127_1003521_7	344747.PM8797T_11389	2.347e-35	138.0	COG1172@1|root,COG1172@2|Bacteria,2IZWQ@203682|Planctomycetes	203682|Planctomycetes	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10440,ko:K10559,ko:K10561	ko02010,map02010	M00212,M00220	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.9	-	-	BPD_transp_2
CH3_k127_1003521_1	344747.PM8797T_11384	4.234e-188	599.0	COG1129@1|root,COG1129@2|Bacteria,2IWTU@203682|Planctomycetes	2|Bacteria	P	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system	rbsA_3	-	3.6.3.17	ko:K10441,ko:K17210	ko02010,map02010	M00212,M00592	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.21	-	-	ABC_tran
CH3_k127_1003521_2	344747.PM8797T_11379	4.532e-130	423.0	COG1879@1|root,COG1879@2|Bacteria,2IYMH@203682|Planctomycetes	203682|Planctomycetes	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
CH3_k127_1003521_4	797209.ZOD2009_14571	3.158e-67	257.0	COG1621@1|root,arCOG08134@2157|Archaea,2XUXA@28890|Euryarchaeota,23UA6@183963|Halobacteria	183963|Halobacteria	G	COG1621 Beta-fructosidases (levanase invertase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_32C,Glyco_hydro_32N
CH3_k127_1003521_8	1403819.BATR01000164_gene5643	1.173e-16	95.0	COG2010@1|root,COG2010@2|Bacteria,46V0R@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PSCyt1,PSCyt2,PSD1
CH3_k127_1003521_9	1303518.CCALI_01840	6.904e-13	79.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
CH3_k127_1003521_10	1227352.C173_18071	1.126e-12	72.0	COG0697@1|root,COG0697@2|Bacteria,1VP2K@1239|Firmicutes,4I1UM@91061|Bacilli,26WQN@186822|Paenibacillaceae	91061|Bacilli	EG	Protein of unknown function (DUF2569)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2569
CH3_k127_1003521_11	1340493.JNIF01000003_gene2695	2.135e-08	63.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_1003521_13	1340493.JNIF01000003_gene2695	1.781e-05	51.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_1003521_14	278957.ABEA03000117_gene1086	0.0001264	56.0	COG3664@1|root,COG3664@2|Bacteria,46XQU@74201|Verrucomicrobia,3K962@414999|Opitutae	414999|Opitutae	G	PFAM glycoside hydrolase family 39	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_1003521_15	979556.MTES_1035	0.0001665	56.0	COG3664@1|root,COG3664@2|Bacteria,2IAP4@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 28 family	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,Glyco_hydro_cc
CH3_k127_1003521_12	324057.Pjdr2_1173	8.086e-06	60.0	COG3664@1|root,COG5434@1|root,COG5520@1|root,COG3664@2|Bacteria,COG5434@2|Bacteria,COG5520@2|Bacteria,1VC96@1239|Firmicutes,4HV2Q@91061|Bacilli,2774T@186822|Paenibacillaceae	91061|Bacilli	M	S-layer homology domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Big_4,CBM9_1,Pectate_lyase_3,SLH
CH3_k127_1003521_5	335543.Sfum_1623	1.766e-59	230.0	COG3118@1|root,COG3118@2|Bacteria,1PQ8G@1224|Proteobacteria	1224|Proteobacteria	O	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
CH3_k127_1003521_6	290512.Paes_2385	8.871e-54	198.0	COG1262@1|root,COG1262@2|Bacteria,1FF87@1090|Chlorobi	1090|Chlorobi	O	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
CH3_k127_1003521_0	861299.J421_1753	1.998e-263	854.0	COG0446@1|root,COG4888@1|root,COG0446@2|Bacteria,COG4888@2|Bacteria	2|Bacteria	G	ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,Pyr_redox_2,UnbV_ASPIC,VCBS
CH3_k127_10043776_0	530564.Psta_0336	1.408e-70	248.0	COG0134@1|root,COG0134@2|Bacteria,2IX3M@203682|Planctomycetes	203682|Planctomycetes	E	Belongs to the TrpC family	trpC	GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
CH3_k127_10043776_3	984262.SGRA_1645	0.0006831	50.0	COG1404@1|root,COG1404@2|Bacteria,4NTJJ@976|Bacteroidetes	976|Bacteroidetes	O	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	LTD
CH3_k127_10043776_2	1123508.JH636439_gene1741	5.258e-08	60.0	COG3335@1|root,COG3335@2|Bacteria,2IZX0@203682|Planctomycetes	203682|Planctomycetes	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
CH3_k127_10043776_1	595536.ADVE02000003_gene4037	2.669e-57	207.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1P76X@1224|Proteobacteria,2U16U@28211|Alphaproteobacteria,36Y82@31993|Methylocystaceae	28211|Alphaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
CH3_k127_10049938_1	335543.Sfum_2246	8.199e-70	238.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42NCZ@68525|delta/epsilon subdivisions,2WK3X@28221|Deltaproteobacteria,2MRHY@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	iAF987.Gmet_1547	ACR_tran
CH3_k127_10049938_3	1403819.BATR01000184_gene6388	2.408e-22	102.0	COG4566@1|root,COG4566@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	ko:K14987	ko02020,map02020	M00524	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
CH3_k127_10049938_2	1353531.AZNX01000006_gene5683	1.684e-60	217.0	COG4566@1|root,COG4566@2|Bacteria,1RDKT@1224|Proteobacteria,2U7ZD@28211|Alphaproteobacteria,4BM44@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	PFAM Response regulator receiver domain, Bacterial regulatory proteins, luxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CH3_k127_10049938_0	335543.Sfum_0581	4.782e-91	332.0	COG2202@1|root,COG2984@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2984@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,HATPase_c,HisKA,PAS_3
CH3_k127_10059903_5	195250.CM001776_gene4007	7.607e-33	135.0	COG0454@1|root,COG0456@2|Bacteria,1GHNN@1117|Cyanobacteria,1H4EJ@1129|Synechococcus	1117|Cyanobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_10059903_8	1096546.WYO_2614	4.792e-10	65.0	COG4453@1|root,COG4453@2|Bacteria,1PW0X@1224|Proteobacteria,2V2IS@28211|Alphaproteobacteria,1JYKH@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1778)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1778
CH3_k127_10059903_2	497964.CfE428DRAFT_5266	1.126e-99	340.0	COG1520@1|root,COG1520@2|Bacteria,46THI@74201|Verrucomicrobia	74201|Verrucomicrobia	S	SMART Pyrrolo-quinoline quinone	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CH3_k127_10059903_0	1121904.ARBP01000009_gene4249	5.326e-183	584.0	COG4948@1|root,COG4948@2|Bacteria,4NI24@976|Bacteroidetes,47N24@768503|Cytophagia	976|Bacteroidetes	M	mandelate racemase muconate lactonizing	-	-	4.2.1.8	ko:K08323	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
CH3_k127_10059903_4	1121875.KB907550_gene801	6.986e-96	329.0	COG0684@1|root,COG0684@2|Bacteria,4NF3M@976|Bacteroidetes,1HYXI@117743|Flavobacteriia	976|Bacteroidetes	H	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
CH3_k127_10059903_1	1449126.JQKL01000012_gene3514	2.462e-134	437.0	COG0343@1|root,COG0343@2|Bacteria,1TNZ4@1239|Firmicutes,247NJ@186801|Clostridia,267ZX@186813|unclassified Clostridiales	186801|Clostridia	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
CH3_k127_10059903_7	1089550.ATTH01000002_gene84	2.257e-12	75.0	COG3000@1|root,COG3000@2|Bacteria,4NES7@976|Bacteroidetes	976|Bacteroidetes	I	sterol desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
CH3_k127_10059903_3	1122169.AREN01000009_gene642	4.541e-97	331.0	COG3550@1|root,COG3550@2|Bacteria,1N458@1224|Proteobacteria,1RNYG@1236|Gammaproteobacteria,1JFTD@118969|Legionellales	118969|Legionellales	S	Pfam:HipA_N	-	-	-	-	-	-	-	-	-	-	-	-	Couple_hipA,HipA_C
CH3_k127_10059903_6	1305735.JAFT01000005_gene2369	1.552e-18	93.0	COG1396@1|root,COG1396@2|Bacteria,1N8D1@1224|Proteobacteria,2U832@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
CH3_k127_10062582_3	518766.Rmar_1742	4.812e-50	186.0	COG2133@1|root,COG2133@2|Bacteria,4PKJE@976|Bacteroidetes,1FJG8@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CH3_k127_10062582_0	768706.Desor_3179	6.754e-175	599.0	COG5492@1|root,COG5492@2|Bacteria,1TS8J@1239|Firmicutes,24A7I@186801|Clostridia,262NZ@186807|Peptococcaceae	186801|Clostridia	N	Leucine rich repeats (6 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,LRR_5
CH3_k127_10062582_10	641112.ACOK01000054_gene3779	8.721e-09	70.0	COG4886@1|root,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Flg_new,LRR_5
CH3_k127_10062582_5	1089548.KI783301_gene2493	5.264e-34	153.0	COG3291@1|root,COG5184@1|root,COG5492@1|root,COG3291@2|Bacteria,COG5184@2|Bacteria,COG5492@2|Bacteria,1VW0A@1239|Firmicutes,4HWE6@91061|Bacilli,3WFP4@539002|Bacillales incertae sedis	2|Bacteria	DZ	S-layer homology domain	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_5,Cadherin-like,DUF1735,DUF4347,DUF5011,F5_F8_type_C,Gram_pos_anchor,He_PIG,HemolysinCabind,Laminin_G_3,SLH,SdrD_B,fn3
CH3_k127_10062582_1	156889.Mmc1_2003	1.969e-69	248.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2TR2B@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Sel1 domain protein repeat-containing protein	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
CH3_k127_10062582_6	1173028.ANKO01000193_gene5867	1.712e-21	108.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,1G4N6@1117|Cyanobacteria	1117|Cyanobacteria	KLT	Serine Threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
CH3_k127_10062582_4	56780.SYN_03067	1.381e-36	149.0	COG2913@1|root,COG2913@2|Bacteria	2|Bacteria	J	Gram-negative-bacterium-type cell outer membrane assembly	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SmpA_OmlA,SusD-like_3
CH3_k127_10062582_2	323259.Mhun_0476	1.067e-63	228.0	COG0500@1|root,arCOG01791@2157|Archaea,2XZTQ@28890|Euryarchaeota	28890|Euryarchaeota	Q	Methyltransferase type 11	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Methyltransf_25
CH3_k127_10062582_9	56780.SYN_03067	2.078e-09	65.0	COG2913@1|root,COG2913@2|Bacteria	2|Bacteria	J	Gram-negative-bacterium-type cell outer membrane assembly	-	-	-	ko:K21572	-	-	-	-	ko00000,ko02000	8.A.46.1,8.A.46.3	-	-	SmpA_OmlA,SusD-like_3
CH3_k127_10133552_1	313628.LNTAR_13872	1.845e-20	102.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K01992,ko:K16919	ko02010,map02010	M00254,M00584	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
CH3_k127_10133552_0	41431.PCC8801_4418	1.613e-71	254.0	COG2367@1|root,COG2367@2|Bacteria,1G0DG@1117|Cyanobacteria,3KFP8@43988|Cyanothece	1117|Cyanobacteria	V	Beta-lactamase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase2
CH3_k127_10133552_3	530564.Psta_1300	1.422e-06	61.0	COG1404@1|root,COG2931@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	5_nucleotid_C,CW_binding_2,Calx-beta,HemolysinCabind,LTD,Metallophos,Peptidase_S8
CH3_k127_10133552_2	243090.RB5356	2.82e-13	76.0	COG4968@1|root,COG4968@2|Bacteria,2J4ZS@203682|Planctomycetes	203682|Planctomycetes	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CH3_k127_10158021_9	1499967.BAYZ01000141_gene6156	2.253e-26	109.0	COG4634@1|root,COG4634@2|Bacteria,2NRUB@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Mut7-C
CH3_k127_10158021_4	977880.pRALTA_0046	2.929e-149	493.0	28IHG@1|root,2Z8IP@2|Bacteria,1R4RG@1224|Proteobacteria,2VVIT@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_10158021_13	497964.CfE428DRAFT_3353	4.992e-08	58.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,46SGF@74201|Verrucomicrobia	74201|Verrucomicrobia	H	UBA THIF-type NAD FAD binding protein	thiF	-	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
CH3_k127_10158021_16	1121035.AUCH01000003_gene1396	0.0005261	46.0	2F41P@1|root,33WTC@2|Bacteria,1P4EC@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_10158021_14	553177.CAPSP0001_0648	1.308e-06	59.0	2F41P@1|root,33WTC@2|Bacteria,4PE72@976|Bacteroidetes,1IEPT@117743|Flavobacteriia,1EQRP@1016|Capnocytophaga	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_10158021_2	1303518.CCALI_00532	1.748e-160	515.0	COG0476@1|root,COG0607@1|root,COG1977@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,COG1977@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	moeB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006732,GO:0006777,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0018130,GO:0019344,GO:0019538,GO:0019637,GO:0019720,GO:0019752,GO:0020012,GO:0030312,GO:0030682,GO:0042783,GO:0043170,GO:0043207,GO:0043436,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0061605,GO:0070566,GO:0071704,GO:0071944,GO:0075136,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.7.73,2.7.7.80,2.8.1.11	ko:K03148,ko:K03636,ko:K21029,ko:K21147	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF,ThiS
CH3_k127_10158021_0	886293.Sinac_5668	1.876e-219	688.0	COG2115@1|root,COG2115@2|Bacteria,2IWUS@203682|Planctomycetes	203682|Planctomycetes	G	Belongs to the xylose isomerase family	xylA	GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
CH3_k127_10158021_7	497964.CfE428DRAFT_0773	2.577e-100	336.0	2DBN7@1|root,2ZA2Y@2|Bacteria,46TTS@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
CH3_k127_10158021_10	86416.Clopa_2098	3.722e-24	110.0	2A1FW@1|root,30PPA@2|Bacteria,1UA53@1239|Firmicutes,254CY@186801|Clostridia,36TYS@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_10158021_12	497964.CfE428DRAFT_0773	3.169e-14	75.0	2DBN7@1|root,2ZA2Y@2|Bacteria,46TTS@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
CH3_k127_10158021_1	1210884.HG799465_gene11752	7.433e-188	602.0	COG1012@1|root,COG1012@2|Bacteria,2IYRE@203682|Planctomycetes	203682|Planctomycetes	C	ketoglutarate semialdehyde dehydrogenase	-	-	1.2.1.4	ko:K14519	ko00930,ko01100,ko01120,ko01220,map00930,map01100,map01120,map01220	-	R05099	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
CH3_k127_10158021_11	194439.CT1729	6.69e-20	95.0	COG2189@1|root,COG2852@1|root,COG2189@2|Bacteria,COG2852@2|Bacteria,1FEW7@1090|Chlorobi	1090|Chlorobi	L	DNA methylase	-	-	2.1.1.72	ko:K07316	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
CH3_k127_10158021_6	1123073.KB899242_gene1369	4.86e-120	394.0	COG0329@1|root,COG0329@2|Bacteria,1MXI1@1224|Proteobacteria,1RRFC@1236|Gammaproteobacteria,1X4B2@135614|Xanthomonadales	135614|Xanthomonadales	EM	Belongs to the DapA family	dapA2	-	3.5.4.22	ko:K21062	ko00330,map00330	-	R02280	RC00679	ko00000,ko00001,ko01000	-	-	-	DHDPS
CH3_k127_10158021_15	1346791.M529_01465	3.319e-06	56.0	2CBBT@1|root,33166@2|Bacteria,1N354@1224|Proteobacteria,2USDI@28211|Alphaproteobacteria,2K9BJ@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_10158021_3	497964.CfE428DRAFT_1990	2.482e-159	513.0	COG0665@1|root,COG0665@2|Bacteria,46TXP@74201|Verrucomicrobia	74201|Verrucomicrobia	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
CH3_k127_10158021_5	497964.CfE428DRAFT_1992	8.356e-130	425.0	COG3938@1|root,COG3938@2|Bacteria,46U8C@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Proline racemase	-	-	-	-	-	-	-	-	-	-	-	-	Pro_racemase
CH3_k127_10158021_8	886293.Sinac_7025	1.633e-32	128.0	COG1225@1|root,COG1225@2|Bacteria,2IYHT@203682|Planctomycetes	203682|Planctomycetes	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CH3_k127_10164012_1	1173028.ANKO01000193_gene5879	3.007e-166	528.0	COG0451@1|root,COG0451@2|Bacteria,1G3T6@1117|Cyanobacteria,1HA43@1150|Oscillatoriales	1117|Cyanobacteria	M	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
CH3_k127_10164012_0	1173028.ANKO01000193_gene5880	1.761e-207	669.0	COG2303@1|root,COG2303@2|Bacteria,1G3V7@1117|Cyanobacteria,1H9T9@1150|Oscillatoriales	1117|Cyanobacteria	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N,NAD_binding_8
CH3_k127_10164012_6	1173028.ANKO01000193_gene5881	1.937e-17	97.0	2DJZT@1|root,32UE2@2|Bacteria,1G8K4@1117|Cyanobacteria,1HCD2@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_10164012_2	649638.Trad_2705	1.975e-147	484.0	COG0382@1|root,COG0546@1|root,COG0382@2|Bacteria,COG0546@2|Bacteria	2|Bacteria	S	glycolate biosynthetic process	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD,UbiA
CH3_k127_10164012_8	158787.BSCA_0674	8.644e-05	55.0	COG5305@1|root,COG5305@2|Bacteria,2HZBN@201174|Actinobacteria,4CZKJ@85004|Bifidobacteriales	201174|Actinobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CH3_k127_10164012_4	497964.CfE428DRAFT_2614	7.144e-104	346.0	COG4989@1|root,COG4989@2|Bacteria,46SU2@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CH3_k127_10164012_5	552811.Dehly_1587	2.015e-24	111.0	COG1514@1|root,COG1514@2|Bacteria,2G76S@200795|Chloroflexi,34D41@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
CH3_k127_10164012_7	700598.Niako_1079	1.693e-12	72.0	COG1403@1|root,COG1479@1|root,COG1403@2|Bacteria,COG1479@2|Bacteria,4NHK1@976|Bacteroidetes,1J0FS@117747|Sphingobacteriia	976|Bacteroidetes	L	Protein of unknown function DUF262	-	-	-	-	-	-	-	-	-	-	-	-	DUF262
CH3_k127_10164012_3	251221.35212674	7.882e-122	403.0	COG0265@1|root,COG0265@2|Bacteria,1G3M4@1117|Cyanobacteria	1117|Cyanobacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
CH3_k127_10175246_1	886293.Sinac_6122	7.644e-205	647.0	COG3391@1|root,COG3511@1|root,COG3391@2|Bacteria,COG3511@2|Bacteria,2IYNB@203682|Planctomycetes	203682|Planctomycetes	M	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase,Phosphoesterase
CH3_k127_10175246_7	886293.Sinac_5446	5.698e-05	53.0	COG1595@1|root,COG1595@2|Bacteria,2IZAB@203682|Planctomycetes	203682|Planctomycetes	K	COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
CH3_k127_10175246_6	314230.DSM3645_18701	1.13e-06	52.0	COG1595@1|root,COG1595@2|Bacteria,2IZAB@203682|Planctomycetes	203682|Planctomycetes	K	COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
CH3_k127_10175246_2	452637.Oter_1389	6.282e-150	525.0	COG0515@1|root,COG0515@2|Bacteria,46VB0@74201|Verrucomicrobia,3K8AK@414999|Opitutae	414999|Opitutae	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CH3_k127_10175246_5	452637.Oter_2422	3.066e-57	204.0	COG1595@1|root,COG1595@2|Bacteria,46VAN@74201|Verrucomicrobia	74201|Verrucomicrobia	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
CH3_k127_10175246_0	1122605.KB893643_gene530	4.268e-218	698.0	COG1554@1|root,COG1554@2|Bacteria,4NEWW@976|Bacteroidetes	976|Bacteroidetes	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K15923	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	GH95	-	Glyco_hyd_65N_2
CH3_k127_10175246_3	1396141.BATP01000006_gene5485	3.054e-101	355.0	COG0213@1|root,COG0213@2|Bacteria,46X9Z@74201|Verrucomicrobia,2IV5J@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Pyrimidine nucleoside phosphorylase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
CH3_k127_10175246_4	296591.Bpro_4700	2.992e-92	316.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,2VI90@28216|Betaproteobacteria,4AD0R@80864|Comamonadaceae	28216|Betaproteobacteria	C	Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
CH3_k127_10195724_3	1385510.N781_05820	8.045e-42	157.0	COG0404@1|root,COG0404@2|Bacteria,1TRKX@1239|Firmicutes,4H9MX@91061|Bacilli,2Y9RQ@289201|Pontibacillus	91061|Bacilli	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
CH3_k127_10195724_4	278963.ATWD01000001_gene2445	4.632e-27	121.0	COG1018@1|root,COG1018@2|Bacteria,3Y3FD@57723|Acidobacteria,2JM1U@204432|Acidobacteriia	204432|Acidobacteriia	C	Oxidoreductase FAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	3-alpha,FAD_binding_6,Fer2,MOSC,NAD_binding_1
CH3_k127_10195724_2	278957.ABEA03000097_gene778	6.315e-77	275.0	COG1192@1|root,COG1192@2|Bacteria,46SKQ@74201|Verrucomicrobia,3K7TC@414999|Opitutae	414999|Opitutae	D	ATPase MipZ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
CH3_k127_10195724_5	481448.Minf_1981	3.938e-09	64.0	COG1544@1|root,COG1544@2|Bacteria,46WSI@74201|Verrucomicrobia,37HA3@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	J	Sigma 54 modulation protein / S30EA ribosomal protein	-	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
CH3_k127_10195724_1	497964.CfE428DRAFT_2596	1.799e-89	310.0	COG0402@1|root,COG0402@2|Bacteria,46TB5@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Amidohydrolase family	ssnA	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
CH3_k127_10195724_0	497964.CfE428DRAFT_3334	5.63e-97	329.0	COG0156@1|root,COG0156@2|Bacteria,46TTU@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	bioF	-	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CH3_k127_10230996_10	411477.PARMER_03655	9.391e-68	243.0	COG3250@1|root,COG3250@2|Bacteria,4NIBS@976|Bacteroidetes,2FPZ2@200643|Bacteroidia,22ZBT@171551|Porphyromonadaceae	976|Bacteroidetes	G	alpha-L-rhamnosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106
CH3_k127_10230996_4	118161.KB235922_gene1342	1.183e-168	558.0	COG3420@1|root,COG3420@2|Bacteria,1GPUW@1117|Cyanobacteria,3VJI4@52604|Pleurocapsales	1117|Cyanobacteria	P	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
CH3_k127_10230996_5	1158294.JOMI01000007_gene112	7.881e-166	534.0	COG5434@1|root,COG5434@2|Bacteria,4NIYD@976|Bacteroidetes,2FRQ9@200643|Bacteroidia	976|Bacteroidetes	M	Pectate lyase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectate_lyase_3
CH3_k127_10230996_0	1396141.BATP01000030_gene3773	0.0	1066.0	COG3250@1|root,COG3387@1|root,COG3250@2|Bacteria,COG3387@2|Bacteria	2|Bacteria	G	glucan 1,4-alpha-glucosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1793,DUF4964,DUF4965,DUF5127,RicinB_lectin_2
CH3_k127_10230996_2	886293.Sinac_0949	3.539e-232	733.0	COG3250@1|root,COG3250@2|Bacteria,2IWTW@203682|Planctomycetes	203682|Planctomycetes	G	Glycosyl hydrolases family 2	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_43
CH3_k127_10230996_1	661478.OP10G_1743	7.403e-274	865.0	COG3533@1|root,COG3533@2|Bacteria	2|Bacteria	S	Beta-L-arabinofuranosidase, GH127	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_127,RicinB_lectin_2
CH3_k127_10230996_8	497964.CfE428DRAFT_2508	2.109e-77	263.0	COG0066@1|root,COG0066@2|Bacteria,46TAY@74201|Verrucomicrobia	74201|Verrucomicrobia	E	3-isopropylmalate dehydratase, small subunit	-	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
CH3_k127_10230996_6	357808.RoseRS_3616	2.378e-129	436.0	COG3525@1|root,COG3525@2|Bacteria,2G609@200795|Chloroflexi,376QW@32061|Chloroflexia	32061|Chloroflexia	G	Glycoside hydrolase, family 20	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_20,Glyco_hydro_20b
CH3_k127_10230996_14	278957.ABEA03000060_gene3088	8.993e-22	100.0	COG5074@1|root,COG5074@2|Bacteria,46W5A@74201|Verrucomicrobia,3K8CX@414999|Opitutae	414999|Opitutae	U	SNAP receptor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_10230996_7	1128421.JAGA01000003_gene2773	1.204e-118	401.0	COG1109@1|root,COG1109@2|Bacteria,2NNTH@2323|unclassified Bacteria	2|Bacteria	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	femD	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
CH3_k127_10230996_11	1123070.KB899257_gene2284	1.243e-60	216.0	COG0036@1|root,COG0036@2|Bacteria,46SVX@74201|Verrucomicrobia,2IU4U@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Ribulose-phosphate 3 epimerase family	-	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
CH3_k127_10230996_13	382464.ABSI01000021_gene406	7.271e-41	156.0	COG1528@1|root,COG1528@2|Bacteria	2|Bacteria	P	ferric iron binding	-	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
CH3_k127_10230996_3	1403819.BATR01000164_gene5622	9.553e-223	711.0	COG0465@1|root,COG0465@2|Bacteria,46SB7@74201|Verrucomicrobia,2ITNZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,Peptidase_M41
CH3_k127_10230996_12	198628.Dda3937_00205	1.181e-45	176.0	COG0720@1|root,COG0720@2|Bacteria,1RI4P@1224|Proteobacteria,1S3T6@1236|Gammaproteobacteria,2JE6U@204037|Dickeya	1236|Gammaproteobacteria	H	PFAM 6-pyruvoyl tetrahydropterin synthase and	queD	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0070497,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	iECIAI39_1322.ECIAI39_2947,iUTI89_1310.UTI89_C3129,ic_1306.c3324	PTPS
CH3_k127_10230996_9	1134413.ANNK01000094_gene900	2.99e-69	252.0	COG1012@1|root,COG1012@2|Bacteria,1TSYP@1239|Firmicutes,4HE2I@91061|Bacilli,1ZCXK@1386|Bacillus	91061|Bacilli	C	Acyl-CoA reductase (LuxC)	-	-	-	-	-	-	-	-	-	-	-	-	LuxC
CH3_k127_10230996_15	1197130.BAFM01000020_gene2812	2.518e-21	108.0	COG0477@1|root,arCOG00130@2157|Archaea,2XVPQ@28890|Euryarchaeota,23TTF@183963|Halobacteria	183963|Halobacteria	G	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CH3_k127_10258052_3	204669.Acid345_0011	4.672e-58	206.0	COG5316@1|root,COG5316@2|Bacteria,3Y4FP@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139
CH3_k127_10258052_0	251221.35211608	2.289e-130	435.0	COG1899@1|root,COG1899@2|Bacteria,1G448@1117|Cyanobacteria	1117|Cyanobacteria	O	Belongs to the deoxyhypusine synthase family	-	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
CH3_k127_10258052_2	497964.CfE428DRAFT_1462	1.813e-72	256.0	COG0084@1|root,COG0084@2|Bacteria,46SRB@74201|Verrucomicrobia	74201|Verrucomicrobia	L	PFAM TatD-related deoxyribonuclease	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
CH3_k127_10258052_1	497964.CfE428DRAFT_1464	4.223e-89	301.0	COG1179@1|root,COG1179@2|Bacteria,46THP@74201|Verrucomicrobia	74201|Verrucomicrobia	H	PFAM UBA THIF-type NAD FAD binding protein	-	-	-	ko:K22132	-	-	-	-	ko00000,ko03016	-	-	-	ThiF
CH3_k127_10269352_3	497964.CfE428DRAFT_0111	1.925e-14	76.0	2CMJG@1|root,32SEZ@2|Bacteria,46T0G@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_10269352_0	497964.CfE428DRAFT_5033	1.643e-205	643.0	COG1541@1|root,COG1541@2|Bacteria,46UFN@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_10269352_1	314230.DSM3645_18936	6.843e-102	351.0	COG0591@1|root,COG0591@2|Bacteria,2IY5N@203682|Planctomycetes	203682|Planctomycetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
CH3_k127_10269352_4	314230.DSM3645_18931	1.423e-12	71.0	2EJH6@1|root,33D83@2|Bacteria,2J1HK@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF3311)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3311
CH3_k127_10269352_2	243090.RB11663	3.788e-87	298.0	COG0477@1|root,COG0477@2|Bacteria,2IWYM@203682|Planctomycetes	203682|Planctomycetes	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
CH3_k127_1028096_0	1267535.KB906767_gene4768	2.989e-113	385.0	2DBP2@1|root,2ZA71@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_1028096_2	247490.KSU1_C1712	7.776e-22	112.0	2DBP2@1|root,2ZA71@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_1028096_1	1112214.AHIS01000056_gene2938	2.283e-24	120.0	COG5512@1|root,COG5512@2|Bacteria,1R4BG@1224|Proteobacteria,2U415@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Domain of unknown function (DUF5060)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4038,DUF5060
CH3_k127_1028096_3	1046714.AMRX01000006_gene2909	9.076e-14	84.0	COG0265@1|root,COG3637@1|root,COG0265@2|Bacteria,COG3637@2|Bacteria,1MWCG@1224|Proteobacteria,1RZKK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF1565
CH3_k127_1028576_7	456442.Mboo_0115	2.612e-22	110.0	COG1413@1|root,arCOG02966@2157|Archaea,2XSWS@28890|Euryarchaeota	28890|Euryarchaeota	C	PBS lyase	cpcE2	-	-	ko:K22221	-	-	-	-	ko00000	-	-	-	HEAT_2,HEAT_PBS
CH3_k127_1028576_9	382464.ABSI01000010_gene3336	1.885e-09	69.0	COG3064@1|root,COG3064@2|Bacteria,46VZ5@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_1028576_6	481448.Minf_0919	5.412e-40	156.0	COG0811@1|root,COG0811@2|Bacteria,46T1R@74201|Verrucomicrobia,37GG9@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
CH3_k127_1028576_8	1396418.BATQ01000003_gene1334	1.235e-11	75.0	COG0848@1|root,COG0848@2|Bacteria,46T7H@74201|Verrucomicrobia,2IUR9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	Biopolymer transport protein ExbD/TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
CH3_k127_1028576_2	497964.CfE428DRAFT_5395	2.533e-160	514.0	COG0136@1|root,COG0136@2|Bacteria,46S74@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
CH3_k127_1028576_3	1303518.CCALI_00393	2.838e-151	494.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,DUF1080,DUF4241
CH3_k127_1028576_0	1123242.JH636434_gene4648	2.944e-175	562.0	COG0673@1|root,COG0673@2|Bacteria,2IXDR@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CH3_k127_1028576_4	886293.Sinac_4629	1.496e-142	468.0	COG0673@1|root,COG0673@2|Bacteria,2IWX9@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CH3_k127_1028576_5	497964.CfE428DRAFT_3384	3.213e-138	442.0	COG0207@1|root,COG0207@2|Bacteria,46SCY@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
CH3_k127_1028576_1	886293.Sinac_4412	4.651e-172	565.0	COG1216@1|root,COG3250@1|root,COG1216@2|Bacteria,COG3250@2|Bacteria,2J0NC@203682|Planctomycetes	203682|Planctomycetes	G	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CH3_k127_10321552_3	497964.CfE428DRAFT_4937	1.113e-115	382.0	COG0280@1|root,COG0280@2|Bacteria,46SP5@74201|Verrucomicrobia	74201|Verrucomicrobia	C	PFAM phosphate acetyl butaryl transferase	-	-	2.3.1.8	ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTA_PTB
CH3_k127_10321552_1	497964.CfE428DRAFT_4938	1.01e-127	418.0	COG0857@1|root,COG0857@2|Bacteria,46UEZ@74201|Verrucomicrobia	74201|Verrucomicrobia	C	DRTGG domain	-	-	-	ko:K06873	-	-	-	-	ko00000	-	-	-	AAA_26,DRTGG
CH3_k127_10321552_2	1403819.BATR01000134_gene4788	4.758e-125	411.0	COG0079@1|root,COG0079@2|Bacteria,46SFP@74201|Verrucomicrobia,2ITIN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminotransferase class I and II	-	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CH3_k127_10321552_0	1210884.HG799463_gene10258	1.313e-160	516.0	COG0548@1|root,COG1246@1|root,COG0548@2|Bacteria,COG1246@2|Bacteria,2J25N@203682|Planctomycetes	203682|Planctomycetes	E	Amino acid kinase family	-	-	-	-	-	-	-	-	-	-	-	-	AA_kinase,Acetyltransf_1
CH3_k127_10321552_4	1227739.Hsw_1619	6.943e-07	58.0	COG2911@1|root,COG3291@1|root,COG3386@1|root,COG2911@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,4NKIP@976|Bacteroidetes,47YDC@768503|Cytophagia	976|Bacteroidetes	G	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF4394,Gal_Lectin
CH3_k127_10326921_0	234267.Acid_2416	1.473e-164	531.0	COG4287@1|root,COG4287@2|Bacteria	2|Bacteria	S	PhoPQ-activated pathogenicity-related protein	pqaA	-	-	-	-	-	-	-	-	-	-	-	PhoPQ_related
CH3_k127_10326921_6	1303518.CCALI_02658	1.777e-12	77.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
CH3_k127_10326921_2	1123242.JH636435_gene1120	8.245e-97	327.0	COG1506@1|root,COG1506@2|Bacteria,2J1ST@203682|Planctomycetes	203682|Planctomycetes	E	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
CH3_k127_10326921_1	215803.DB30_0528	1.287e-101	343.0	COG0454@1|root,COG0456@2|Bacteria,1PMA3@1224|Proteobacteria,42PYX@68525|delta/epsilon subdivisions,2WKSE@28221|Deltaproteobacteria,2YUVH@29|Myxococcales	28221|Deltaproteobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_10326921_3	382464.ABSI01000011_gene3037	1.384e-77	262.0	COG3837@1|root,COG3837@2|Bacteria,46T0V@74201|Verrucomicrobia,2IU8V@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CH3_k127_10326921_7	1304874.JAFY01000001_gene2557	1.631e-10	65.0	COG1366@1|root,COG1366@2|Bacteria,3TC3U@508458|Synergistetes	508458|Synergistetes	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS_2
CH3_k127_10326921_4	1380394.JADL01000003_gene4839	4.909e-23	104.0	COG2172@1|root,COG2172@2|Bacteria,1N9RD@1224|Proteobacteria,2UCGB@28211|Alphaproteobacteria,2JTM5@204441|Rhodospirillales	204441|Rhodospirillales	T	Histidine kinase-like ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2
CH3_k127_10326921_5	1174528.JH992893_gene5730	2.307e-22	100.0	COG0745@1|root,COG2208@1|root,COG0745@2|Bacteria,COG2208@2|Bacteria,1G1PX@1117|Cyanobacteria	1117|Cyanobacteria	T	Serine phosphatase RsbU regulator of sigma subunit	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	Response_reg,SpoIIE
CH3_k127_10339778_1	313628.LNTAR_07649	1.323e-12	72.0	COG0644@1|root,COG0644@2|Bacteria	2|Bacteria	C	geranylgeranyl reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored,TAT_signal
CH3_k127_10339778_2	114615.BRADO7045	1.584e-10	75.0	COG3664@1|root,COG3664@2|Bacteria,1MX9Q@1224|Proteobacteria,2TWU2@28211|Alphaproteobacteria,3JXZ2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	Glycosyl hydrolase catalytic core	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_cc
CH3_k127_10339778_0	1408224.SAMCCGM7_c3749	8.717e-49	191.0	COG2730@1|root,COG2730@2|Bacteria,1R544@1224|Proteobacteria,2U1MT@28211|Alphaproteobacteria,4BD0S@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	Putative collagen-binding domain of a collagenase	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF4038
CH3_k127_10349514_2	1499967.BAYZ01000088_gene5142	3.861e-08	65.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,2NRIW@2323|unclassified Bacteria	2|Bacteria	S	Outer membrane lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_8
CH3_k127_10349514_1	1157490.EL26_10960	2.069e-26	111.0	COG0316@1|root,COG0316@2|Bacteria,1V6IN@1239|Firmicutes,4HKN2@91061|Bacilli,278HH@186823|Alicyclobacillaceae	91061|Bacilli	S	Belongs to the HesB IscA family	yutM	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
CH3_k127_10349514_0	1396418.BATQ01000093_gene5884	4.467e-314	967.0	COG0422@1|root,COG0422@2|Bacteria,46S5R@74201|Verrucomicrobia,2ITWP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	ThiC-associated domain	-	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
CH3_k127_10360830_2	1396141.BATP01000060_gene4647	4.137e-47	173.0	COG0515@1|root,COG0515@2|Bacteria,46UAE@74201|Verrucomicrobia,2IV44@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_12,WD40
CH3_k127_10360830_0	530564.Psta_1182	2.897e-50	192.0	COG1262@1|root,COG1262@2|Bacteria,2IZ7E@203682|Planctomycetes	203682|Planctomycetes	KLT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
CH3_k127_10360830_3	1396141.BATP01000060_gene4647	1.753e-43	164.0	COG0515@1|root,COG0515@2|Bacteria,46UAE@74201|Verrucomicrobia,2IV44@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_12,WD40
CH3_k127_10360830_4	1123242.JH636435_gene2663	2.503e-31	141.0	COG0526@1|root,COG0526@2|Bacteria,2IXG6@203682|Planctomycetes	203682|Planctomycetes	CO	Thiol-disulfide isomerase and	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CH3_k127_10360830_5	338966.Ppro_2636	9.842e-07	59.0	COG3637@1|root,COG3637@2|Bacteria,1NGKR@1224|Proteobacteria,42XMD@68525|delta/epsilon subdivisions,2WSIW@28221|Deltaproteobacteria,43UMH@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
CH3_k127_10360830_1	290315.Clim_0430	2.701e-48	183.0	COG1409@1|root,COG1785@1|root,COG2931@1|root,COG3391@1|root,COG1409@2|Bacteria,COG1785@2|Bacteria,COG2931@2|Bacteria,COG3391@2|Bacteria,1FDAF@1090|Chlorobi	1090|Chlorobi	P	Belongs to the alkaline phosphatase family	-	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase,SWM_repeat
CH3_k127_10369269_2	314230.DSM3645_08622	2.807e-48	198.0	COG3391@1|root,COG3391@2|Bacteria,2IYRP@203682|Planctomycetes	203682|Planctomycetes	P	RING finger protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,NHL
CH3_k127_10369269_5	1407650.BAUB01000015_gene2280	3.494e-18	100.0	COG1178@1|root,COG1178@2|Bacteria,1GCQ2@1117|Cyanobacteria	1117|Cyanobacteria	P	ABC-type Fe3 transport system permease component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	-
CH3_k127_10369269_6	533240.CRC_01736	8.627e-07	58.0	COG4276@1|root,COG4276@2|Bacteria,1G939@1117|Cyanobacteria,1HNWV@1161|Nostocales	1117|Cyanobacteria	S	Pfam Polyketide cyclase dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_10369269_1	1121403.AUCV01000002_gene446	7.166e-62	226.0	COG1840@1|root,COG1840@2|Bacteria,1MXZ8@1224|Proteobacteria,42P50@68525|delta/epsilon subdivisions,2WKU5@28221|Deltaproteobacteria,2MMX2@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6
CH3_k127_10369269_0	326427.Cagg_0204	9.572e-74	273.0	COG2304@1|root,COG2304@2|Bacteria,2GABP@200795|Chloroflexi,37510@32061|Chloroflexia	32061|Chloroflexia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
CH3_k127_10369269_4	452637.Oter_1500	5.536e-29	123.0	COG3824@1|root,COG3824@2|Bacteria,46WK7@74201|Verrucomicrobia,3K8CH@414999|Opitutae	414999|Opitutae	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
CH3_k127_10369269_3	1356854.N007_11120	1.672e-35	139.0	COG1321@1|root,COG1321@2|Bacteria,1V3IS@1239|Firmicutes,4HH06@91061|Bacilli,278CC@186823|Alicyclobacillaceae	91061|Bacilli	K	Helix-turn-helix diphteria tox regulatory element	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
CH3_k127_10372945_3	1463936.JOJI01000044_gene7868	5.864e-40	160.0	COG1105@1|root,COG1105@2|Bacteria,2GK7E@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the carbohydrate kinase PfkB family	fruK	-	2.7.1.56	ko:K00882	ko00051,map00051	-	R02071	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
CH3_k127_10372945_1	886293.Sinac_7011	3.371e-98	348.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG2755@1|root,COG3794@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,COG2755@2|Bacteria,COG3794@2|Bacteria,2IX6X@203682|Planctomycetes	203682|Planctomycetes	C	Membrane-bound dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cytochrom_C,Cytochrome_CBB3,F5_F8_type_C,HEAT_2,Lipase_GDSL_2
CH3_k127_10372945_2	935845.JADQ01000029_gene1230	2.509e-91	344.0	COG2755@1|root,COG4257@1|root,COG5184@1|root,COG2755@2|Bacteria,COG4257@2|Bacteria,COG5184@2|Bacteria,1UZD4@1239|Firmicutes,4HD48@91061|Bacilli,26VBQ@186822|Paenibacillaceae	91061|Bacilli	DZ	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin-like,RCC1_2,SLH
CH3_k127_10372945_4	870187.Thini_0809	1.535e-09	73.0	COG1404@1|root,COG4932@1|root,COG1404@2|Bacteria,COG4932@2|Bacteria,1MU3S@1224|Proteobacteria,1RSP9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	PKD,P_proprotein,Peptidase_S8
CH3_k127_10372945_5	498211.CJA_2236	2.744e-09	61.0	COG1396@1|root,COG1396@2|Bacteria,1R0M5@1224|Proteobacteria,1TBAA@1236|Gammaproteobacteria,1FHSR@10|Cellvibrio	1236|Gammaproteobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
CH3_k127_10372945_0	240016.ABIZ01000001_gene4136	0.0	1091.0	COG2010@1|root,COG3241@1|root,COG2010@2|Bacteria,COG3241@2|Bacteria	2|Bacteria	C	Transfers electrons from cytochrome c551 to cytochrome oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cytochrom_C,F5_F8_type_C,HEAT_2,Lipase_GDSL_2
CH3_k127_10382639_2	313628.LNTAR_20062	3.832e-10	70.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
CH3_k127_10382639_1	382464.ABSI01000013_gene1723	3.132e-109	383.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4369,Redoxin,Thioredoxin_8,UnbV_ASPIC,VCBS
CH3_k127_10382639_0	1396141.BATP01000030_gene3719	9.37e-148	486.0	COG3119@1|root,COG3211@1|root,COG3656@1|root,COG5337@1|root,COG3119@2|Bacteria,COG3211@2|Bacteria,COG3656@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	phoX	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	CotH,DUF839
CH3_k127_10382972_1	886293.Sinac_2716	6.148e-97	327.0	COG1477@1|root,COG1477@2|Bacteria,2IY0F@203682|Planctomycetes	203682|Planctomycetes	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
CH3_k127_10382972_2	452637.Oter_0820	9.39e-84	284.0	COG0012@1|root,COG0012@2|Bacteria	2|Bacteria	J	GTP binding	ychF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
CH3_k127_10382972_3	1396141.BATP01000032_gene4325	9.335e-52	194.0	COG0265@1|root,COG0265@2|Bacteria,46W40@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_10382972_0	1396141.BATP01000032_gene4324	1.78e-218	698.0	COG0265@1|root,COG0265@2|Bacteria,46SHP@74201|Verrucomicrobia,2IU51@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Trypsin	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
CH3_k127_10382972_4	278957.ABEA03000008_gene3274	0.0008996	43.0	COG1082@1|root,COG1082@2|Bacteria,46ZE0@74201|Verrucomicrobia,3K81E@414999|Opitutae	414999|Opitutae	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CH3_k127_10421590_6	251221.35213566	7.629e-34	140.0	COG1404@1|root,COG5549@1|root,COG1404@2|Bacteria,COG5549@2|Bacteria,1G72X@1117|Cyanobacteria	1117|Cyanobacteria	O	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_10421590_0	671143.DAMO_1057	9.948e-146	499.0	COG1391@1|root,COG1391@2|Bacteria	2|Bacteria	H	[glutamate-ammonia-ligase] adenylyltransferase activity	glnE	GO:0000166,GO:0000287,GO:0000820,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006521,GO:0006541,GO:0006542,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008882,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0010565,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0019222,GO:0019752,GO:0030554,GO:0031323,GO:0032553,GO:0032555,GO:0032559,GO:0033238,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
CH3_k127_10421590_4	398767.Glov_2755	3.216e-63	229.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	exoA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K16557	-	-	-	-	ko00000,ko01000,ko01003	-	GT2	-	Glyco_tranf_2_3,Glycos_transf_2
CH3_k127_10421590_7	278957.ABEA03000019_gene1865	4.364e-32	133.0	2DRPS@1|root,33CHR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2204
CH3_k127_10421590_5	497964.CfE428DRAFT_0259	4.282e-59	209.0	COG2151@1|root,COG2151@2|Bacteria,46SWX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Pfam:DUF59	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
CH3_k127_10421590_9	240016.ABIZ01000001_gene2614	1.346e-06	63.0	COG2373@1|root,COG2885@1|root,COG3210@1|root,COG5563@1|root,COG2373@2|Bacteria,COG2885@2|Bacteria,COG3210@2|Bacteria,COG5563@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	3.1.4.3	ko:K01114,ko:K12287,ko:K15125,ko:K16191,ko:K20276	ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,ko05133,map00562,map00564,map00565,map01100,map01110,map02024,map04919,map05133	-	R01312,R02027,R02052,R03332,R07381	RC00017,RC00425	ko00000,ko00001,ko00536,ko01000,ko02000,ko02042,ko02044	1.B.6.1.3	-	-	DUF1573,OmpA
CH3_k127_10421590_1	1121904.ARBP01000023_gene4986	4.256e-106	392.0	COG3210@1|root,COG4886@1|root,COG4935@1|root,COG3210@2|Bacteria,COG4886@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K15125,ko:K20276	ko02024,ko05133,map02024,map05133	-	-	-	ko00000,ko00001,ko00536	-	-	-	CHU_C,Flg_new,Glug,LRR_5,PKD,P_proprotein,SprB
CH3_k127_10421590_8	1116472.MGMO_57c00180	1.069e-09	74.0	COG3055@1|root,COG3291@1|root,COG3055@2|Bacteria,COG3291@2|Bacteria,1R1H9@1224|Proteobacteria,1T52V@1236|Gammaproteobacteria,1XEUH@135618|Methylococcales	135618|Methylococcales	EH	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PKD,fn3
CH3_k127_10421590_3	429009.Adeg_0968	4.158e-91	319.0	COG1092@1|root,COG1092@2|Bacteria,1TRAJ@1239|Firmicutes,247TI@186801|Clostridia,42F3J@68295|Thermoanaerobacterales	186801|Clostridia	J	SMART PUA domain containing protein	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,PUA
CH3_k127_10421590_2	1303518.CCALI_01952	1.438e-91	315.0	COG0318@1|root,COG0318@2|Bacteria	2|Bacteria	IQ	PFAM AMP-dependent synthetase and ligase	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
CH3_k127_10434704_9	395495.Lcho_0773	4.098e-05	46.0	COG3335@1|root,COG3335@2|Bacteria,1N5WI@1224|Proteobacteria,2VHUB@28216|Betaproteobacteria,1KPAP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
CH3_k127_10434704_4	909663.KI867150_gene711	2.368e-65	233.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,43A29@68525|delta/epsilon subdivisions,2X21K@28221|Deltaproteobacteria,2MS4J@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	-	-	-	-	-	-	-	-	-	-	FKBP_C
CH3_k127_10434704_0	478741.JAFS01000002_gene146	5.26e-140	474.0	COG0793@1|root,COG0793@2|Bacteria,46S88@74201|Verrucomicrobia,37FVV@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	tail specific protease	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF3340,PDZ,Peptidase_S41
CH3_k127_10434704_3	1519464.HY22_08455	9.565e-68	235.0	COG0225@1|root,COG0225@2|Bacteria,1FE4X@1090|Chlorobi	1090|Chlorobi	C	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K07304,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
CH3_k127_10434704_1	525904.Tter_1408	1.434e-107	362.0	COG2262@1|root,COG2262@2|Bacteria,2NNWI@2323|unclassified Bacteria	2|Bacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006464,GO:0006468,GO:0006518,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006996,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018105,GO:0018193,GO:0018209,GO:0019001,GO:0019222,GO:0019538,GO:0019843,GO:0022411,GO:0030554,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0032790,GO:0032984,GO:0032988,GO:0034248,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0036211,GO:0036289,GO:0043021,GO:0043022,GO:0043023,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:2000112	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
CH3_k127_10434704_2	648996.Theam_0501	2.447e-68	243.0	COG0324@1|root,COG0324@2|Bacteria,2G3QA@200783|Aquificae	200783|Aquificae	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
CH3_k127_10434704_5	1265505.ATUG01000003_gene311	6.487e-56	206.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,42M2I@68525|delta/epsilon subdivisions,2WNPT@28221|Deltaproteobacteria,2MIZH@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
CH3_k127_10434704_6	497964.CfE428DRAFT_1107	5.421e-43	164.0	COG1595@1|root,COG1595@2|Bacteria,46SZG@74201|Verrucomicrobia	74201|Verrucomicrobia	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CH3_k127_10434704_8	1248916.ANFY01000009_gene96	2.668e-12	81.0	COG3055@1|root,COG3055@2|Bacteria,1N85X@1224|Proteobacteria	1224|Proteobacteria	M	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_10446891_3	1123008.KB905693_gene1177	2.447e-31	126.0	COG3394@1|root,COG3394@2|Bacteria,4NFY5@976|Bacteroidetes	976|Bacteroidetes	G	PFAM YdjC family protein	-	-	3.5.1.105	ko:K03478	-	-	-	-	ko00000,ko01000	-	-	-	YdjC
CH3_k127_10446891_1	1123242.JH636434_gene4911	1.352e-130	430.0	COG3356@1|root,COG3356@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
CH3_k127_10446891_0	644966.Tmar_0705	3.278e-154	505.0	COG2936@1|root,COG2936@2|Bacteria,1TT0H@1239|Firmicutes,24BT1@186801|Clostridia,3WD7J@538999|Clostridiales incertae sedis	186801|Clostridia	S	PFAM X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
CH3_k127_10446891_4	661367.LLO_3002	1.571e-10	76.0	COG1470@1|root,COG1520@1|root,COG3291@1|root,COG4447@1|root,COG5184@1|root,COG1470@2|Bacteria,COG1520@2|Bacteria,COG3291@2|Bacteria,COG4447@2|Bacteria,COG5184@2|Bacteria,1RBUT@1224|Proteobacteria,1S27R@1236|Gammaproteobacteria,1JEPR@118969|Legionellales	118969|Legionellales	DZ	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122
CH3_k127_10446891_2	498761.HM1_0137	3.715e-36	160.0	COG1470@1|root,COG3210@1|root,COG4733@1|root,COG4886@1|root,COG5492@1|root,COG1470@2|Bacteria,COG3210@2|Bacteria,COG4733@2|Bacteria,COG4886@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_2,CHU_C,Flg_new,LRR_5,RCC1,SLH
CH3_k127_10446891_5	714943.Mucpa_7167	2.456e-08	68.0	COG1208@1|root,COG3420@1|root,COG5184@1|root,COG5492@1|root,COG1208@2|Bacteria,COG3420@2|Bacteria,COG5184@2|Bacteria,COG5492@2|Bacteria,4NMRB@976|Bacteroidetes,1ITFX@117747|Sphingobacteriia	976|Bacteroidetes	P	Protein of unknown function (DUF3494)	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF3494,Flg_new
CH3_k127_10459785_0	497964.CfE428DRAFT_1447	0.0	1156.0	COG0265@1|root,COG0823@1|root,COG2234@1|root,COG0265@2|Bacteria,COG0823@2|Bacteria,COG2234@2|Bacteria,46T85@74201|Verrucomicrobia	74201|Verrucomicrobia	OU	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,PD40,PDZ_2,Peptidase_M28
CH3_k127_10459785_1	1123070.KB899252_gene961	1.21e-155	497.0	COG1077@1|root,COG1077@2|Bacteria,46SAA@74201|Verrucomicrobia,2ITYI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	D	Actin	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
CH3_k127_10459785_5	457570.Nther_0516	1.925e-29	128.0	COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,249M3@186801|Clostridia	186801|Clostridia	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
CH3_k127_10459785_3	481448.Minf_1718	4.146e-91	326.0	COG0768@1|root,COG0768@2|Bacteria,46SE6@74201|Verrucomicrobia,37G03@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	D	Penicillin binding protein transpeptidase domain	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Peptidase_M56,Transpeptidase
CH3_k127_10459785_4	452637.Oter_0292	4.094e-85	296.0	COG0772@1|root,COG0772@2|Bacteria,46SQT@74201|Verrucomicrobia,3K7H4@414999|Opitutae	414999|Opitutae	D	Belongs to the SEDS family	-	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
CH3_k127_10459785_2	497964.CfE428DRAFT_3932	1.318e-103	350.0	COG1530@1|root,COG1530@2|Bacteria,46S5S@74201|Verrucomicrobia	74201|Verrucomicrobia	J	TIGRFAM ribonuclease, Rne Rng family	cafA	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G
CH3_k127_10491780_16	649638.Trad_0681	0.0004365	52.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.1.4.46,3.2.1.8	ko:K01126,ko:K01181	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	LRR_5,Laminin_G_3,NLPC_P60,PKD,Reprolysin_4,fn3
CH3_k127_10491780_2	1403819.BATR01000125_gene4494	1.44e-173	581.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,46UI8@74201|Verrucomicrobia,2IV8V@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
CH3_k127_10491780_5	485918.Cpin_3102	5.583e-58	210.0	COG2197@1|root,COG2197@2|Bacteria,4NHTM@976|Bacteroidetes,1ITQW@117747|Sphingobacteriia	976|Bacteroidetes	T	COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CH3_k127_10491780_8	1429851.X548_02885	7.524e-20	106.0	COG3210@1|root,COG4625@1|root,COG3210@2|Bacteria,COG4625@2|Bacteria,1MU92@1224|Proteobacteria,1T1MJ@1236|Gammaproteobacteria,1X4X8@135614|Xanthomonadales	135614|Xanthomonadales	U	Autotransporter beta-domain	yapH	-	-	-	-	-	-	-	-	-	-	-	ESPR,PATR
CH3_k127_10491780_11	661478.OP10G_0266	3.127e-12	77.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02650,ko:K02679	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10
CH3_k127_10491780_6	1537715.JQFJ01000002_gene1346	7.35e-32	146.0	COG2911@1|root,COG3210@1|root,COG3468@1|root,COG4625@1|root,COG2911@2|Bacteria,COG3210@2|Bacteria,COG3468@2|Bacteria,COG4625@2|Bacteria,1MU92@1224|Proteobacteria,2TX9B@28211|Alphaproteobacteria,2KENE@204457|Sphingomonadales	204457|Sphingomonadales	MU	Autotransporter beta-domain	-	-	-	ko:K19231	-	-	-	-	ko00000,ko02000	1.B.12	-	-	PATR
CH3_k127_10491780_9	344747.PM8797T_04455	6.192e-14	81.0	COG2165@1|root,COG2165@2|Bacteria,2J1XE@203682|Planctomycetes	203682|Planctomycetes	NU	Protein of unknown function (DUF1559)	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_10
CH3_k127_10491780_14	794903.OPIT5_22725	2.606e-09	69.0	COG2165@1|root,COG2165@2|Bacteria,46YHE@74201|Verrucomicrobia,3K9KI@414999|Opitutae	414999|Opitutae	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
CH3_k127_10491780_7	1026882.MAMP_01900	5.474e-30	140.0	COG3210@1|root,COG4625@1|root,COG3210@2|Bacteria,COG4625@2|Bacteria,1MXIP@1224|Proteobacteria,1RSAX@1236|Gammaproteobacteria,461F5@72273|Thiotrichales	72273|Thiotrichales	U	Large exoproteins involved in heme utilization or adhesion	-	-	-	-	-	-	-	-	-	-	-	-	PATR
CH3_k127_10491780_10	1142394.PSMK_04880	1.71e-13	83.0	COG2165@1|root,COG2165@2|Bacteria,2IY1V@203682|Planctomycetes	203682|Planctomycetes	NU	TIGRFAM prepilin-type N-terminal cleavage methylation domain	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CH3_k127_10491780_13	521674.Plim_1480	8.029e-12	76.0	COG2165@1|root,COG2165@2|Bacteria,2IYXM@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CH3_k127_10491780_1	1396141.BATP01000033_gene4254	3.735e-186	620.0	COG5434@1|root,COG5434@2|Bacteria,46TEZ@74201|Verrucomicrobia,2IWAI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Belongs to the glycosyl hydrolase 28 family	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_10491780_12	1463820.JOGW01000001_gene5446	4.747e-12	80.0	COG1409@1|root,COG5492@1|root,COG1409@2|Bacteria,COG5492@2|Bacteria,2GKTR@201174|Actinobacteria	201174|Actinobacteria	N	polysaccharide lyase family 8	-	-	4.2.2.1	ko:K01727	-	-	-	-	ko00000,ko01000	-	PL8	-	Lyase_8,Lyase_8_C,Lyase_8_N
CH3_k127_10491780_0	1396418.BATQ01000020_gene5035	1.426e-207	657.0	COG3119@1|root,COG3119@2|Bacteria,46ZJS@74201|Verrucomicrobia,2IVBK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CH3_k127_10491780_4	497964.CfE428DRAFT_1056	4.919e-119	398.0	COG3119@1|root,COG3119@2|Bacteria,46VGR@74201|Verrucomicrobia	74201|Verrucomicrobia	NP	Ig domain protein group 2 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Sulfatase
CH3_k127_10491780_3	234267.Acid_1623	5.788e-120	395.0	COG2801@1|root,COG2801@2|Bacteria,3Y821@57723|Acidobacteria	57723|Acidobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve_3
CH3_k127_10495762_1	742725.HMPREF9450_01242	1.632e-80	271.0	COG3408@1|root,COG3408@2|Bacteria,4NHST@976|Bacteroidetes,2FQ71@200643|Bacteroidia	976|Bacteroidetes	G	Alpha-L-rhamnosidase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H,Bac_rhamnosid_C
CH3_k127_10495762_0	595460.RRSWK_06562	1.05e-276	876.0	COG3408@1|root,COG3408@2|Bacteria,2J2NJ@203682|Planctomycetes	203682|Planctomycetes	G	Alpha-L-rhamnosidase N-terminal domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
CH3_k127_10502268_4	314230.DSM3645_26699	2.534e-134	454.0	COG1196@1|root,COG1196@2|Bacteria,2IYCW@203682|Planctomycetes	203682|Planctomycetes	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_10502268_2	497964.CfE428DRAFT_0777	1.824e-178	585.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
CH3_k127_10502268_5	497964.CfE428DRAFT_0775	8.763e-122	398.0	COG1721@1|root,COG1721@2|Bacteria	2|Bacteria	E	protein (some members contain a von Willebrand factor type A (vWA) domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CH3_k127_10502268_3	497964.CfE428DRAFT_0774	1.095e-154	495.0	COG0714@1|root,COG0714@2|Bacteria,46TCY@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM ATPase associated with various cellular activities AAA_3	-	-	-	-	-	-	-	-	-	-	-	-	AAA_3
CH3_k127_10502268_6	344747.PM8797T_32255	2.685e-110	363.0	2DBN7@1|root,2ZA2Y@2|Bacteria,2IYBW@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
CH3_k127_10502268_1	497964.CfE428DRAFT_0772	1.937e-248	797.0	COG0457@1|root,COG0457@2|Bacteria,46U9B@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Peptidase MA superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2,TPR_16,TPR_19
CH3_k127_10502268_7	521674.Plim_3779	4.339e-109	369.0	COG2755@1|root,COG2755@2|Bacteria,2IZBK@203682|Planctomycetes	203682|Planctomycetes	E	Pectate lyase	-	-	4.2.2.2	ko:K01728	ko00040,ko02024,map00040,map02024	-	R02361,R06240	RC00049,RC00705	ko00000,ko00001,ko01000	-	-	-	Pec_lyase
CH3_k127_10502268_0	204669.Acid345_4052	1.294e-260	831.0	COG0204@1|root,COG0318@1|root,COG0477@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,COG2814@2|Bacteria,3Y4RT@57723|Acidobacteria	57723|Acidobacteria	IQ	Phosphate acyltransferases	-	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase,MFS_1
CH3_k127_10516747_3	497964.CfE428DRAFT_0260	1.401e-54	193.0	COG0822@1|root,COG0822@2|Bacteria,46VAC@74201|Verrucomicrobia	74201|Verrucomicrobia	C	NifU-like N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	NifU_N
CH3_k127_10516747_2	497964.CfE428DRAFT_0261	2.178e-58	211.0	COG0607@1|root,COG0607@2|Bacteria,46VE6@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CH3_k127_10516747_0	382464.ABSI01000007_gene4191	1.339e-176	578.0	COG2833@1|root,COG2833@2|Bacteria,46YYE@74201|Verrucomicrobia,2ITUP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Protein of unknown function (DUF455)	-	-	-	-	-	-	-	-	-	-	-	-	DUF455
CH3_k127_10516747_1	794903.OPIT5_13745	9.028e-172	547.0	COG0513@1|root,COG0513@2|Bacteria,46U0S@74201|Verrucomicrobia,3K72X@414999|Opitutae	414999|Opitutae	L	DEAD DEAH box helicase	-	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
CH3_k127_10534737_5	575540.Isop_0126	6.514e-14	83.0	COG2165@1|root,COG2165@2|Bacteria,2J1UJ@203682|Planctomycetes	2|Bacteria	NU	TIGRFAM prepilin-type N-terminal cleavage methylation domain	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CH3_k127_10534737_2	344747.PM8797T_26405	8.482e-105	357.0	COG0673@1|root,COG0673@2|Bacteria,2IWX9@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CH3_k127_10534737_4	1303518.CCALI_00602	1.196e-14	85.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
CH3_k127_10534737_3	382464.ABSI01000013_gene1723	1.546e-98	353.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4369,Redoxin,Thioredoxin_8,UnbV_ASPIC,VCBS
CH3_k127_10534737_0	497964.CfE428DRAFT_5300	1.767e-159	513.0	COG0673@1|root,COG0673@2|Bacteria,46S8U@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CH3_k127_10534737_1	1210884.HG799468_gene13605	8.758e-152	498.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1,Polysacc_deac_1,Polysacc_deac_3
CH3_k127_10540763_1	880072.Desac_2552	1.121e-38	153.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,42M28@68525|delta/epsilon subdivisions,2WJPF@28221|Deltaproteobacteria,2MQKP@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
CH3_k127_10540763_0	945713.IALB_0983	1.063e-99	339.0	COG4299@1|root,COG4299@2|Bacteria	2|Bacteria	G	COGs COG4299 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624,DUF5009
CH3_k127_10540763_3	794903.OPIT5_15450	3.985e-19	96.0	COG2165@1|root,COG2165@2|Bacteria,46XJA@74201|Verrucomicrobia,3K9FD@414999|Opitutae	414999|Opitutae	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
CH3_k127_10540763_2	237368.SCABRO_00978	6.134e-31	134.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	BACON,DUF11,Fil_haemagg_2,Flg_new,PATR
CH3_k127_10540763_4	378806.STAUR_2423	2.229e-09	61.0	COG3464@1|root,COG3464@2|Bacteria,1R8B7@1224|Proteobacteria,43BG6@68525|delta/epsilon subdivisions,2X6UH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_10546141_3	497964.CfE428DRAFT_5353	6.029e-23	115.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,HATPase_c,HD_5,Response_reg,T2SSE_N
CH3_k127_10546141_4	497964.CfE428DRAFT_4596	2.315e-21	109.0	COG0745@1|root,COG1716@1|root,COG0745@2|Bacteria,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	ko:K02283,ko:K02454,ko:K03220,ko:K03466	ko03070,ko05111,map03070,map05111	M00331,M00332	-	-	ko00000,ko00001,ko00002,ko02035,ko02044,ko03036	3.A.12,3.A.15,3.A.6.1	-	-	Cytochrom_c3_2,FHA,FtsK_SpoIIIE,Response_reg,T2SSE,Yop-YscD_cpl,Yop-YscD_ppl
CH3_k127_10546141_0	925409.KI911562_gene2080	1.669e-149	487.0	COG0673@1|root,COG0673@2|Bacteria,4NF96@976|Bacteroidetes,1IX0E@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CH3_k127_10546141_1	1396418.BATQ01000073_gene500	2.574e-39	154.0	COG0204@1|root,COG0204@2|Bacteria,46SYR@74201|Verrucomicrobia,2IUG8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
CH3_k127_10546141_2	266748.HY04_14380	9.82e-24	104.0	COG0283@1|root,COG0283@2|Bacteria,4NEMB@976|Bacteroidetes,1HXBA@117743|Flavobacteriia,3ZNHX@59732|Chryseobacterium	976|Bacteroidetes	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
CH3_k127_105916_9	1123070.KB899255_gene1412	2.466e-31	125.0	COG0379@1|root,COG0379@2|Bacteria,46SA1@74201|Verrucomicrobia,2ITV3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Quinolinate synthetase A protein	-	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
CH3_k127_105916_13	497964.CfE428DRAFT_0242	4.481e-20	107.0	COG1858@1|root,COG3391@1|root,COG3534@1|root,COG5276@1|root,COG1858@2|Bacteria,COG3391@2|Bacteria,COG3534@2|Bacteria,COG5276@2|Bacteria,46U43@74201|Verrucomicrobia	74201|Verrucomicrobia	C	SMART LamG domain protein jellyroll fold domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,LVIVD,Laminin_G_3,PKD
CH3_k127_105916_5	1168289.AJKI01000040_gene3174	2.054e-72	277.0	2DYE6@1|root,349BE@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_105916_15	1550091.JROE01000004_gene1873	3.542e-09	58.0	COG0379@1|root,COG0379@2|Bacteria,4NDVX@976|Bacteroidetes,1INZ3@117747|Sphingobacteriia	976|Bacteroidetes	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
CH3_k127_105916_4	452637.Oter_1332	9.83e-80	275.0	COG1075@1|root,COG1075@2|Bacteria,46VJF@74201|Verrucomicrobia,3K9J6@414999|Opitutae	414999|Opitutae	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_105916_0	1242864.D187_003088	5.05e-189	623.0	COG2931@1|root,COG3055@1|root,COG2931@2|Bacteria,COG3055@2|Bacteria,1Q4PQ@1224|Proteobacteria,4347S@68525|delta/epsilon subdivisions,2X34Y@28221|Deltaproteobacteria,2YUAC@29|Myxococcales	28221|Deltaproteobacteria	V	Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_4,TSP_3
CH3_k127_105916_8	1125701.HMPREF1221_01616	2.765e-48	191.0	COG2407@1|root,COG2407@2|Bacteria	2|Bacteria	G	Converts the aldose L-fucose into the corresponding ketose L-fuculose	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_105916_7	1279009.ADICEAN_01670	5.93e-62	218.0	COG0590@1|root,COG0590@2|Bacteria,4NNMU@976|Bacteroidetes,47PPK@768503|Cytophagia	976|Bacteroidetes	FJ	MafB19-like deaminase	guaD	-	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	-	MafB19-deam,dCMP_cyt_deam_1
CH3_k127_105916_3	1128427.KB904821_gene1968	1.05e-82	289.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
CH3_k127_105916_11	292564.Cyagr_1911	9.627e-24	114.0	COG2337@1|root,COG2337@2|Bacteria,1G7JA@1117|Cyanobacteria	1117|Cyanobacteria	T	PFAM PemK-like protein	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
CH3_k127_105916_1	497964.CfE428DRAFT_5010	1.32e-175	562.0	COG1940@1|root,COG1940@2|Bacteria,46SBQ@74201|Verrucomicrobia	74201|Verrucomicrobia	GK	carbohydrate kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_105916_2	530564.Psta_1962	1.359e-94	327.0	28J2H@1|root,2Z8YZ@2|Bacteria,2IWTN@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_105916_14	1120950.KB892753_gene6100	2.551e-13	83.0	COG3534@1|root,COG3534@2|Bacteria	2|Bacteria	G	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,Glyco_hydro_39
CH3_k127_105916_6	479434.Sthe_1775	3.279e-71	249.0	COG1136@1|root,COG1136@2|Bacteria,2G6B5@200795|Chloroflexi,27YCE@189775|Thermomicrobia	189775|Thermomicrobia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CH3_k127_105916_12	40571.JOEA01000008_gene2733	3.635e-23	117.0	COG0577@1|root,COG0577@2|Bacteria,2GJTZ@201174|Actinobacteria,4DXTW@85010|Pseudonocardiales	201174|Actinobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CH3_k127_105916_10	868131.MSWAN_1282	6.901e-31	131.0	COG0655@1|root,arCOG02573@2157|Archaea,2XVMU@28890|Euryarchaeota,23PMW@183925|Methanobacteria	183925|Methanobacteria	S	PFAM NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
CH3_k127_105916_16	1210884.HG799464_gene10380	1.179e-07	53.0	COG3293@1|root,COG3293@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	ko:K07492	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
CH3_k127_10592624_19	234267.Acid_0845	7.232e-23	108.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	cpeZ	-	-	ko:K05384,ko:K05386	ko00196,ko01100,map00196,map01100	-	-	-	ko00000,ko00001,ko00194	-	-	-	HEAT_2
CH3_k127_10592624_15	1408473.JHXO01000006_gene1364	7.307e-47	191.0	COG1082@1|root,COG1082@2|Bacteria,4NJJZ@976|Bacteroidetes,2FQWU@200643|Bacteroidia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CH3_k127_10592624_14	314230.DSM3645_14090	1.018e-51	206.0	COG1413@1|root,COG3828@1|root,COG1413@2|Bacteria,COG3828@2|Bacteria,2IX8S@203682|Planctomycetes	203682|Planctomycetes	C	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CH3_k127_10592624_8	452637.Oter_3509	6.194e-89	311.0	COG0673@1|root,COG0673@2|Bacteria,46TMZ@74201|Verrucomicrobia,3K8Y2@414999|Opitutae	414999|Opitutae	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CH3_k127_10592624_17	497964.CfE428DRAFT_0900	3.111e-32	134.0	2C6YV@1|root,3392Q@2|Bacteria,46T7D@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_10592624_16	452637.Oter_3681	4.013e-33	135.0	COG0680@1|root,COG0680@2|Bacteria	2|Bacteria	C	spore germination	hycI	GO:0003674,GO:0003824,GO:0004175,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.23.51	ko:K00442,ko:K03605,ko:K04656,ko:K08315	ko00680,ko01100,ko01120,map00680,map01100,map01120	-	R03025	RC02628	ko00000,ko00001,ko01000,ko01002	-	-	iAF987.Gmet_3329	HycI
CH3_k127_10592624_1	452637.Oter_3680	3.013e-255	799.0	COG3259@1|root,COG3259@2|Bacteria,46STG@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Nickel-dependent hydrogenase	frhA	-	1.8.98.5	ko:K14126	ko00680,map00680	-	R00019,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
CH3_k127_10592624_5	452637.Oter_3679	6.525e-155	498.0	COG1941@1|root,COG1941@2|Bacteria,46T7U@74201|Verrucomicrobia	74201|Verrucomicrobia	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	frhG	-	1.8.98.5	ko:K14128	ko00680,map00680	-	R00019,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	Oxidored_q6
CH3_k127_10592624_11	880073.Calab_3045	2.741e-60	213.0	COG1908@1|root,COG1908@2|Bacteria,2NPFI@2323|unclassified Bacteria	2|Bacteria	C	Methyl-viologen-reducing hydrogenase, delta subunit	bamF	-	1.8.98.5,1.8.98.6	ko:K14127,ko:K14128	ko00680,map00680	-	R00019,R11943,R11944	RC00011	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_2083	Fer4,FlpD,HTH_5
CH3_k127_10592624_0	452637.Oter_3677	9.531e-318	985.0	COG1148@1|root,COG1148@2|Bacteria	2|Bacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,Pyr_redox_2
CH3_k127_10592624_7	309801.trd_0150	2.176e-113	378.0	COG0247@1|root,COG0247@2|Bacteria,2G5X6@200795|Chloroflexi	200795|Chloroflexi	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CCG
CH3_k127_10592624_4	1238450.VIBNISOn1_970135	8.441e-164	537.0	COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,1RNBY@1236|Gammaproteobacteria,1XSGD@135623|Vibrionales	135623|Vibrionales	C	Cysteine-rich domain	-	-	-	ko:K21834	-	-	-	-	ko00000	-	-	-	CCG,DUF3483,Fer4_8
CH3_k127_10592624_9	525909.Afer_0970	8.339e-78	271.0	COG2025@1|root,COG2025@2|Bacteria,2GJWH@201174|Actinobacteria,4CNP3@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Electron transfer flavoprotein domain	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
CH3_k127_10592624_13	562970.Btus_2493	1.681e-52	194.0	COG2086@1|root,COG2086@2|Bacteria,1VUFC@1239|Firmicutes	1239|Firmicutes	C	Electron transfer flavoprotein domain	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
CH3_k127_10592624_10	1379698.RBG1_1C00001G0051	7.247e-73	260.0	COG2048@1|root,COG2048@2|Bacteria,2NQP7@2323|unclassified Bacteria	2|Bacteria	C	Heterodisulfide reductase subunit B	hdrB	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
CH3_k127_10592624_18	880073.Calab_3048	2.929e-30	132.0	COG1150@1|root,COG1150@2|Bacteria,2NQ2K@2323|unclassified Bacteria	2|Bacteria	C	4Fe-4S dicluster domain	hdrC	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389,ko:K03390,ko:K16887,ko:K18930	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3424	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17,Fer4_7,Fer4_8,Fer4_9
CH3_k127_10592624_20	1499967.BAYZ01000059_gene4768	9.615e-16	83.0	COG0745@1|root,COG0745@2|Bacteria	1499967.BAYZ01000059_gene4768|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_10592624_12	644282.Deba_1749	4.349e-58	216.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,43C2A@68525|delta/epsilon subdivisions,2X7CW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,Response_reg
CH3_k127_10592624_6	316067.Geob_1632	9.244e-140	471.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MRH@68525|delta/epsilon subdivisions,2WM8D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase HAMP	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,sCache_3_3
CH3_k127_10592624_21	452637.Oter_3675	6.988e-14	75.0	COG1150@1|root,COG1150@2|Bacteria	2|Bacteria	C	4Fe-4S dicluster domain	hdrC	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389,ko:K03390,ko:K16887,ko:K18930	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3424	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17,Fer4_7,Fer4_8,Fer4_9
CH3_k127_10592624_3	903818.KI912269_gene259	3.572e-185	597.0	COG2864@1|root,COG2864@2|Bacteria,3Y6QW@57723|Acidobacteria	57723|Acidobacteria	C	Prokaryotic cytochrome b561	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Ni_hydr_CYTB
CH3_k127_10592624_2	1121920.AUAU01000001_gene2269	4.199e-252	785.0	COG2864@1|root,COG2864@2|Bacteria,3Y6QW@57723|Acidobacteria	2|Bacteria	C	Prokaryotic cytochrome b561	cbcY	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Cytochrome_C7,Ni_hydr_CYTB,Paired_CXXCH_1,Rhodanese
CH3_k127_10597376_1	1346791.M529_08415	2.633e-152	491.0	COG2382@1|root,COG2382@2|Bacteria,1QU4Q@1224|Proteobacteria,2UCAB@28211|Alphaproteobacteria,2K2IZ@204457|Sphingomonadales	204457|Sphingomonadales	P	Putative esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase
CH3_k127_10597376_0	714943.Mucpa_3835	1.211e-202	666.0	COG3534@1|root,COG3534@2|Bacteria,4NH8M@976|Bacteroidetes,1IVFD@117747|Sphingobacteriia	976|Bacteroidetes	G	Alpha-L-arabinofuranosidase C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-L-AF_C
CH3_k127_10597376_5	1173026.Glo7428_2145	4.002e-29	136.0	COG2730@1|root,COG2730@2|Bacteria,1G7EB@1117|Cyanobacteria	1117|Cyanobacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase
CH3_k127_10597376_6	234267.Acid_2103	6.427e-22	98.0	COG2382@1|root,COG2382@2|Bacteria,3Y2ZN@57723|Acidobacteria	2|Bacteria	GP	Putative esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase,Glyco_hydro_10
CH3_k127_10597376_7	1462527.CCDM010000004_gene3638	2.114e-06	51.0	2EJBT@1|root,33D2X@2|Bacteria,1VKP4@1239|Firmicutes,4HRCQ@91061|Bacilli,23N7H@182709|Oceanobacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_10597376_3	926550.CLDAP_00200	1.762e-54	202.0	COG0266@1|root,COG0266@2|Bacteria,2G6BB@200795|Chloroflexi	200795|Chloroflexi	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
CH3_k127_10597376_4	644801.Psest_3899	1.394e-42	163.0	COG1926@1|root,COG1926@2|Bacteria,1RAG8@1224|Proteobacteria,1S3SH@1236|Gammaproteobacteria,1Z115@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	S	phosphoribosyltransferases	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	Pribosyltran
CH3_k127_10597376_2	639282.DEFDS_0119	2.285e-94	317.0	COG0528@1|root,COG0528@2|Bacteria,2GEZE@200930|Deferribacteres	200930|Deferribacteres	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
CH3_k127_10615178_0	616991.JPOO01000003_gene1322	6.942e-196	618.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,1HWR3@117743|Flavobacteriia,23G5Z@178469|Arenibacter	976|Bacteroidetes	G	Glycosyl hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_92
CH3_k127_10615178_1	497964.CfE428DRAFT_4864	3.988e-68	239.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_10615178_2	497964.CfE428DRAFT_2981	1.262e-29	123.0	COG0515@1|root,COG0515@2|Bacteria,46U28@74201|Verrucomicrobia	74201|Verrucomicrobia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF1648,DUF4019,Pkinase
CH3_k127_10620766_13	1349767.GJA_24	1.195e-08	56.0	COG0477@1|root,COG2814@2|Bacteria,1MUZ8@1224|Proteobacteria,2VI8P@28216|Betaproteobacteria,473IT@75682|Oxalobacteraceae	28216|Betaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	MFS_1
CH3_k127_10620766_3	234267.Acid_1881	1.072e-115	379.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CH3_k127_10620766_5	234267.Acid_1882	9.736e-77	265.0	2DF1J@1|root,2ZQ4G@2|Bacteria	2|Bacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
CH3_k127_10620766_14	880073.Calab_3105	6.101e-07	62.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	ampG	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	BT1,MFS_1
CH3_k127_10620766_12	1121939.L861_16535	2.945e-10	62.0	COG2331@1|root,COG2331@2|Bacteria,1NMRY@1224|Proteobacteria	1224|Proteobacteria	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
CH3_k127_10620766_7	1123368.AUIS01000029_gene1290	1.539e-49	183.0	COG1499@1|root,COG1499@2|Bacteria,1RD49@1224|Proteobacteria,1S4E9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	ribosomal large subunit export from nucleus	-	-	-	-	-	-	-	-	-	-	-	-	NMD3
CH3_k127_10620766_10	296591.Bpro_3359	4.459e-33	133.0	COG0527@1|root,COG0527@2|Bacteria,1REUY@1224|Proteobacteria,2VS69@28216|Betaproteobacteria	28216|Betaproteobacteria	E	ACT domain	-	-	-	-	-	-	-	-	-	-	-	-	ACT,ACT_6
CH3_k127_10620766_4	909663.KI867150_gene1088	1.387e-90	303.0	COG1394@1|root,COG1394@2|Bacteria,1PA1A@1224|Proteobacteria,42VQ3@68525|delta/epsilon subdivisions,2WT1Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	-	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
CH3_k127_10620766_1	909663.KI867150_gene1089	8.847e-273	845.0	COG1156@1|root,COG1156@2|Bacteria,1R4RB@1224|Proteobacteria,42PJC@68525|delta/epsilon subdivisions,2WJB9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	-	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
CH3_k127_10620766_0	909663.KI867150_gene1090	0.0	1017.0	COG1155@1|root,COG1155@2|Bacteria,1MWRR@1224|Proteobacteria,42NKK@68525|delta/epsilon subdivisions,2WIQQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit	-	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
CH3_k127_10620766_6	909663.KI867150_gene1091	6.626e-60	215.0	2FA6P@1|root,342FE@2|Bacteria	2|Bacteria	S	ATP synthase (E/31 kDa) subunit	-	-	-	-	-	-	-	-	-	-	-	-	vATP-synt_E
CH3_k127_10620766_9	909663.KI867150_gene1092	1.125e-36	140.0	COG1436@1|root,COG1436@2|Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpF	-	-	ko:K02122	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_F
CH3_k127_10620766_11	909663.KI867150_gene1093	7.187e-31	125.0	COG0636@1|root,COG0636@2|Bacteria,1NG0V@1224|Proteobacteria,42XT7@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	ATP synthase subunit C	-	-	-	ko:K02124	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_C
CH3_k127_10620766_8	452637.Oter_1848	1.149e-37	145.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CH3_k127_10620766_2	909663.KI867150_gene1094	2.879e-165	528.0	COG1269@1|root,COG1269@2|Bacteria,1QGFB@1224|Proteobacteria,42SY2@68525|delta/epsilon subdivisions,2X5C4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	V-type ATPase 116kDa subunit family	-	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
CH3_k127_10622184_0	682795.AciX8_0946	5.216e-63	235.0	COG1874@1|root,COG1874@2|Bacteria,3Y6EF@57723|Acidobacteria,2JKVE@204432|Acidobacteriia	204432|Acidobacteriia	G	Domain of unknown function (DUF4832)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4832
CH3_k127_10622184_1	1195236.CTER_0486	6.024e-18	98.0	COG2133@1|root,COG2182@1|root,COG3507@1|root,COG3669@1|root,COG3979@1|root,COG2133@2|Bacteria,COG2182@2|Bacteria,COG3507@2|Bacteria,COG3669@2|Bacteria,COG3979@2|Bacteria,1VRJN@1239|Firmicutes,24DFN@186801|Clostridia,3WIA2@541000|Ruminococcaceae	186801|Clostridia	G	PA14	-	-	-	-	-	-	-	-	-	-	-	-	PA14,RsgI_N
CH3_k127_10622322_0	452637.Oter_1108	7.896e-56	200.0	COG2335@1|root,COG2335@2|Bacteria,46VJN@74201|Verrucomicrobia,3K9JN@414999|Opitutae	414999|Opitutae	M	Four repeated domains in the Fasciclin I family of proteins, present in many other contexts.	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
CH3_k127_10622322_6	13690.CP98_02314	7.884e-05	45.0	COG0655@1|root,COG0655@2|Bacteria,1MW7N@1224|Proteobacteria,2TR4Z@28211|Alphaproteobacteria,2K6DT@204457|Sphingomonadales	204457|Sphingomonadales	S	Flavodoxin-like fold	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
CH3_k127_10622322_4	1335757.SPICUR_03845	7.405e-22	101.0	COG2199@1|root,COG3852@1|root,COG3706@2|Bacteria,COG3852@2|Bacteria,1R7HC@1224|Proteobacteria,1RZKN@1236|Gammaproteobacteria,1X0QN@135613|Chromatiales	135613|Chromatiales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS,PAS_9
CH3_k127_10622322_2	595460.RRSWK_06787	3.177e-42	162.0	COG3449@1|root,COG3449@2|Bacteria,2J2ST@203682|Planctomycetes	203682|Planctomycetes	L	SOUL heme-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SOUL
CH3_k127_10622322_1	452637.Oter_4559	1.163e-45	170.0	COG0783@1|root,COG0783@2|Bacteria,46VAF@74201|Verrucomicrobia,3K84T@414999|Opitutae	414999|Opitutae	P	Belongs to the Dps family	-	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
CH3_k127_10622322_5	1089550.ATTH01000001_gene516	2.171e-13	76.0	COG1028@1|root,COG1028@2|Bacteria,4NFXD@976|Bacteroidetes,1FJCX@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CH3_k127_10622322_3	1504672.669786077	1.136e-28	119.0	COG3046@1|root,COG3046@2|Bacteria,1MUHX@1224|Proteobacteria,2VHTR@28216|Betaproteobacteria,4AB3G@80864|Comamonadaceae	28216|Betaproteobacteria	S	Deoxyribodipyrimidine photo-lyase-related protein	-	-	-	ko:K06876	-	-	-	-	ko00000	-	-	-	DPRP
CH3_k127_10648503_1	497964.CfE428DRAFT_4764	8.628e-306	962.0	COG0178@1|root,COG0178@2|Bacteria,46SAF@74201|Verrucomicrobia	74201|Verrucomicrobia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
CH3_k127_10648503_0	234267.Acid_0094	0.0	1065.0	COG1960@1|root,COG1960@2|Bacteria	2|Bacteria	I	acyl-CoA dehydrogenase activity	fadE23	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CH3_k127_10648503_2	452637.Oter_4534	2.692e-225	702.0	COG0458@1|root,COG0458@2|Bacteria,46UZV@74201|Verrucomicrobia,3K7MQ@414999|Opitutae	414999|Opitutae	F	Carbamoyl-phosphate synthetase large chain, oligomerisation domain	-	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
CH3_k127_10661135_1	1132441.KI519454_gene1142	2.165e-178	569.0	COG1554@1|root,COG1554@2|Bacteria,2GJXJ@201174|Actinobacteria	201174|Actinobacteria	G	Glycosyl hydrolase family 65, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_10661135_2	1396141.BATP01000003_gene5168	2.543e-136	451.0	2EKQJ@1|root,33EEC@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_10661135_0	1122931.AUAE01000013_gene2105	1.624e-194	647.0	COG3250@1|root,COG3250@2|Bacteria,4NEP8@976|Bacteroidetes,2FWKT@200643|Bacteroidia	976|Bacteroidetes	G	Glycosyl hydrolases family 2, TIM barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
CH3_k127_10661135_3	391603.FBALC1_06473	4.098e-24	120.0	COG2133@1|root,COG3291@1|root,COG3511@1|root,COG5563@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG3511@2|Bacteria,COG5563@2|Bacteria	2|Bacteria	M	phospholipase C	psrP1	-	1.1.3.9	ko:K04618	ko00052,map00052	-	R01098	RC00194	ko00000,ko00001,ko01000	-	-	-	CHU_C,DUF1929,F5_F8_type_C,GSDH,fn3
CH3_k127_10661135_5	278957.ABEA03000106_gene1817	1.407e-16	89.0	COG4968@1|root,COG4968@2|Bacteria,46Y7B@74201|Verrucomicrobia,3K91Z@414999|Opitutae	414999|Opitutae	NU	Prepilin-type N-terminal cleavage methylation domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_10661135_4	864051.BurJ1DRAFT_3700	3.098e-17	96.0	COG0726@1|root,COG0823@1|root,COG2911@1|root,COG2931@1|root,COG3210@1|root,COG3420@1|root,COG0726@2|Bacteria,COG0823@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3420@2|Bacteria,1MU7T@1224|Proteobacteria,2WI67@28216|Betaproteobacteria,1KMDS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	MQU	Domain of unknown function (DUF4347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347
CH3_k127_10670398_0	1210884.HG799464_gene10582	5.961e-88	299.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	mtsE	-	-	ko:K11089	ko05322,map05322	-	-	-	ko00000,ko00001	-	-	-	TROVE,VWA_2
CH3_k127_10670398_1	1403819.BATR01000181_gene6219	3.201e-55	208.0	COG0583@1|root,COG0583@2|Bacteria,46V82@74201|Verrucomicrobia,2IVST@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CH3_k127_10670398_2	1303518.CCALI_00163	3.156e-32	144.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,Metallophos
CH3_k127_10680633_3	1396141.BATP01000038_gene1209	3.965e-06	49.0	COG1879@1|root,COG1879@2|Bacteria,46XDV@74201|Verrucomicrobia,2IVKX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Periplasmic binding protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_4
CH3_k127_10680633_0	384765.SIAM614_30241	2.371e-149	490.0	COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,2TQJV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	ABC transporter	alsA	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
CH3_k127_10680633_1	1396141.BATP01000038_gene1207	1.658e-144	466.0	COG1172@1|root,COG1172@2|Bacteria,46V1Z@74201|Verrucomicrobia,2IVHK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
CH3_k127_10680633_2	1501230.ET33_33510	3.727e-90	309.0	COG2273@1|root,COG2273@2|Bacteria,1TR5U@1239|Firmicutes,4HACU@91061|Bacilli,26SWK@186822|Paenibacillaceae	91061|Bacilli	G	1,3--beta-D-glucan 3-glucanohydrolase	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	CBM_4_9,Glyco_hydro_16,RicinB_lectin_2
CH3_k127_10707718_2	314230.DSM3645_26039	2.285e-28	127.0	COG4409@1|root,COG4409@2|Bacteria,2IX8T@203682|Planctomycetes	203682|Planctomycetes	G	BNR repeat-like domain	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2
CH3_k127_10707718_1	1499967.BAYZ01000159_gene538	1.355e-69	251.0	COG0407@1|root,COG0407@2|Bacteria,2NRD5@2323|unclassified Bacteria	2|Bacteria	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
CH3_k127_10707718_0	497964.CfE428DRAFT_0769	6.615e-94	325.0	COG1520@1|root,COG1520@2|Bacteria,46UNX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CH3_k127_10731959_0	864051.BurJ1DRAFT_3700	1.265e-175	610.0	COG0726@1|root,COG0823@1|root,COG2911@1|root,COG2931@1|root,COG3210@1|root,COG3420@1|root,COG0726@2|Bacteria,COG0823@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3420@2|Bacteria,1MU7T@1224|Proteobacteria,2WI67@28216|Betaproteobacteria,1KMDS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	MQU	Domain of unknown function (DUF4347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347
CH3_k127_10731959_1	497964.CfE428DRAFT_2621	3.562e-165	529.0	COG1030@1|root,COG1030@2|Bacteria,46TAS@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD,SDH_sah
CH3_k127_10731959_3	497964.CfE428DRAFT_2620	6.779e-118	385.0	COG0330@1|root,COG0330@2|Bacteria,46VDU@74201|Verrucomicrobia	74201|Verrucomicrobia	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
CH3_k127_10731959_7	278957.ABEA03000149_gene4042	5.435e-19	88.0	2BGYY@1|root,32AZ2@2|Bacteria,46ZHP@74201|Verrucomicrobia,3K9QU@414999|Opitutae	414999|Opitutae	S	Zinc ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
CH3_k127_10731959_8	1484460.JSWG01000009_gene451	1.379e-12	77.0	COG2356@1|root,COG2374@1|root,COG2356@2|Bacteria,COG2374@2|Bacteria,4NINJ@976|Bacteroidetes,1HZEY@117743|Flavobacteriia	976|Bacteroidetes	L	endonuclease I	-	-	-	-	-	-	-	-	-	-	-	-	LTD
CH3_k127_10731959_4	1232410.KI421415_gene3077	9.357e-73	254.0	COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,42MAG@68525|delta/epsilon subdivisions,2WM94@28221|Deltaproteobacteria,43S5I@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Belongs to the TrpC family	trpC	-	4.1.1.48,5.3.1.24	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508,R03509	RC00944,RC00945	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2494	IGPS
CH3_k127_10731959_2	382464.ABSI01000011_gene3025	2.674e-131	428.0	COG1186@1|root,COG1186@2|Bacteria,46SAW@74201|Verrucomicrobia,2ITHK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
CH3_k127_10731959_5	358396.C445_20550	2.407e-56	207.0	COG0451@1|root,arCOG03095@2157|Archaea,2XTPI@28890|Euryarchaeota,23STT@183963|Halobacteria	183963|Halobacteria	M	NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
CH3_k127_10731959_6	1170562.Cal6303_5068	1.398e-50	182.0	COG0826@1|root,COG0826@2|Bacteria,1G3NG@1117|Cyanobacteria,1HM59@1161|Nostocales	1117|Cyanobacteria	O	Peptidase family U32	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32,Peptidase_U32_C
CH3_k127_10755383_1	1396141.BATP01000001_gene5396	3.881e-159	507.0	COG0205@1|root,COG0205@2|Bacteria,46U0X@74201|Verrucomicrobia,2IV5S@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Phosphofructokinase	-	-	-	-	-	-	-	-	-	-	-	-	PFK
CH3_k127_10755383_2	69042.WH5701_07541	4.611e-153	489.0	COG1052@1|root,COG1052@2|Bacteria,1G028@1117|Cyanobacteria,1GZTS@1129|Synechococcus	1117|Cyanobacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase	ddh	-	1.1.1.28	ko:K03778	ko00620,ko01120,map00620,map01120	-	R00704	RC00044	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
CH3_k127_10755383_0	497964.CfE428DRAFT_1127	3.034e-204	646.0	COG0469@1|root,COG0469@2|Bacteria	2|Bacteria	G	pyruvate kinase activity	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
CH3_k127_10755383_3	452637.Oter_2995	2.391e-44	164.0	COG0191@1|root,COG0191@2|Bacteria,46TAJ@74201|Verrucomicrobia,3K7BF@414999|Opitutae	414999|Opitutae	G	Fructose-bisphosphate aldolase class-II	-	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
CH3_k127_10763527_2	1396141.BATP01000057_gene3053	1.317e-118	416.0	COG2312@1|root,COG3209@1|root,COG2312@2|Bacteria,COG3209@2|Bacteria,46XD5@74201|Verrucomicrobia,2IVHX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Fn3_assoc,LTD
CH3_k127_10763527_7	414684.RC1_4050	0.0001759	53.0	COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,2TS39@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	PFAM secretion protein HlyD family protein	-	-	-	ko:K03543	-	M00701	-	-	ko00000,ko00002,ko02000	8.A.1.1	-	-	Biotin_lipoyl_2,HlyD,HlyD_3,HlyD_D23
CH3_k127_10763527_6	1144932.ATTF01000017_gene1171	6.651e-23	108.0	COG1285@1|root,COG1285@2|Bacteria,1PD3I@1224|Proteobacteria,2UKD1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4956)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
CH3_k127_10763527_5	382464.ABSI01000013_gene1546	2.394e-23	110.0	COG5036@1|root,COG5036@2|Bacteria,46VA7@74201|Verrucomicrobia	74201|Verrucomicrobia	P	VTC domain	-	-	-	-	-	-	-	-	-	-	-	-	VTC
CH3_k127_10763527_0	1123242.JH636438_gene5875	1.853e-181	580.0	COG1520@1|root,COG1520@2|Bacteria,2IYNF@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
CH3_k127_10763527_1	649638.Trad_2886	9.31e-160	519.0	COG1057@1|root,COG1057@2|Bacteria	2|Bacteria	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18,3.6.1.55	ko:K00969,ko:K03574	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	CTP_transf_like
CH3_k127_10763527_3	1382359.JIAL01000001_gene1578	1.597e-90	304.0	COG0623@1|root,COG0623@2|Bacteria,3Y3EN@57723|Acidobacteria,2JHZZ@204432|Acidobacteriia	204432|Acidobacteriia	I	Enoyl- acyl-carrier-protein reductase NADH	-	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CH3_k127_10763527_4	292459.STH496	4.881e-28	119.0	COG1051@1|root,COG1051@2|Bacteria,1VHQV@1239|Firmicutes,24SJS@186801|Clostridia	186801|Clostridia	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CH3_k127_10780241_1	1173028.ANKO01000018_gene1201	1.986e-16	94.0	COG1404@1|root,COG2931@1|root,COG3210@1|root,COG3940@1|root,COG4447@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3940@2|Bacteria,COG4447@2|Bacteria,1G4T5@1117|Cyanobacteria,1HHYV@1150|Oscillatoriales	1117|Cyanobacteria	U	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4347,Haemagg_act,HemolysinCabind
CH3_k127_10780241_0	247634.GPB2148_909	1.244e-76	267.0	COG1619@1|root,COG1619@2|Bacteria,1MWIY@1224|Proteobacteria,1RQT8@1236|Gammaproteobacteria,1J6J9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	Microcin C7 resistance	ldcA	GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009050,GO:0009056,GO:0009254,GO:0009987,GO:0016787,GO:0019538,GO:0030203,GO:0034641,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	iAPECO1_1312.APECO1_304,iECABU_c1320.ECABU_c14580,iECED1_1282.ECED1_1334,iECOK1_1307.ECOK1_1338,iECS88_1305.ECS88_1255,iLF82_1304.LF82_1171,iNRG857_1313.NRG857_06085,iSFV_1184.SFV_1201,iSFxv_1172.SFxv_1357,iS_1188.S1271,iUMN146_1321.UM146_11125,iUTI89_1310.UTI89_C1378,ic_1306.c1641	Peptidase_S66
CH3_k127_10780241_2	661478.OP10G_2992	3.044e-13	79.0	COG4537@1|root,COG4537@2|Bacteria	2|Bacteria	U	Required for transformation and DNA binding	comGC	GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944	-	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	M00331,M00429	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
CH3_k127_10783116_6	926566.Terro_2389	1.635e-33	133.0	COG3119@1|root,COG3119@2|Bacteria,3Y7MP@57723|Acidobacteria,2JNZP@204432|Acidobacteriia	57723|Acidobacteria	P	TIGRFAM Tat (twin-arginine translocation) pathway signal sequence	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CH3_k127_10783116_1	1403819.BATR01000133_gene4740	6.728e-178	598.0	COG3540@1|root,COG3540@2|Bacteria,46XER@74201|Verrucomicrobia,2IVPT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Alkaline phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_10783116_0	497964.CfE428DRAFT_4754	8.268e-192	639.0	COG3119@1|root,COG3119@2|Bacteria,46UET@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,Sulfatase_C
CH3_k127_10783116_10	395961.Cyan7425_0454	6.303e-13	70.0	COG3153@1|root,COG3153@2|Bacteria,1GK4X@1117|Cyanobacteria,3KIFY@43988|Cyanothece	1117|Cyanobacteria	S	PFAM GCN5-related N-acetyltransferase	-	-	-	ko:K03824	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_9
CH3_k127_10783116_9	296591.Bpro_2383	8.629e-16	85.0	COG0454@1|root,COG0456@2|Bacteria,1RD40@1224|Proteobacteria,2VXVS@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CH3_k127_10783116_5	794903.OPIT5_11625	3.013e-61	220.0	COG1451@1|root,COG1451@2|Bacteria,46VW6@74201|Verrucomicrobia,3K7I9@414999|Opitutae	414999|Opitutae	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
CH3_k127_10783116_4	264732.Moth_2023	1.36e-62	245.0	COG2017@1|root,COG2017@2|Bacteria	2|Bacteria	G	converts alpha-aldose to the beta-anomer	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim,DUF4380
CH3_k127_10783116_3	1089547.KB913013_gene868	3.197e-95	346.0	COG3934@1|root,COG3934@2|Bacteria,4NGQC@976|Bacteroidetes,47M9B@768503|Cytophagia	976|Bacteroidetes	G	Cellulase (glycosyl hydrolase family 5)	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase,Glyco_hydro_2_C
CH3_k127_10783116_7	1210884.HG799463_gene9540	2.268e-29	137.0	COG3250@1|root,COG3250@2|Bacteria,2IWTW@203682|Planctomycetes	203682|Planctomycetes	G	Glycosyl hydrolases family 2	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_43
CH3_k127_10783116_8	1137269.AZWL01000013_gene2716	1.081e-24	108.0	COG3537@1|root,COG3537@2|Bacteria,2GKYM@201174|Actinobacteria	201174|Actinobacteria	G	Alpha-1,2-mannosidase	-	-	-	-	-	-	-	-	-	-	-	-	CBM-like,Glyco_hydro_92,NPCBM_assoc
CH3_k127_10783116_11	497964.CfE428DRAFT_4019	1.367e-10	71.0	COG2081@1|root,COG2081@2|Bacteria	2|Bacteria	N	HI0933 family	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	FAD_oxidored,HI0933_like
CH3_k127_10783116_2	243090.RB605	1.055e-164	528.0	COG3119@1|root,COG3119@2|Bacteria,2J1ZQ@203682|Planctomycetes	203682|Planctomycetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CH3_k127_10834077_0	1123508.JH636439_gene1118	2.179e-226	709.0	COG3119@1|root,COG3119@2|Bacteria,2IXMP@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CH3_k127_10834077_8	402777.KB235903_gene687	4.973e-51	185.0	COG3153@1|root,COG3153@2|Bacteria	2|Bacteria	S	transferase activity, transferring acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
CH3_k127_10834077_1	880073.Calab_3423	3.302e-157	515.0	COG3525@1|root,COG3525@2|Bacteria,2NNQC@2323|unclassified Bacteria	2|Bacteria	G	Glycosyl hydrolase family 20, catalytic domain	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	CHB_HEX_C_1,Fn3_assoc,Glyco_hydro_20,Glyco_hydro_20b,PA14
CH3_k127_10834077_10	180332.JTGN01000003_gene1997	1.334e-40	169.0	COG0407@1|root,COG0407@2|Bacteria,1VEQ3@1239|Firmicutes,24RQ2@186801|Clostridia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
CH3_k127_10834077_5	443143.GM18_2242	6.237e-103	356.0	COG2730@1|root,COG2730@2|Bacteria,1R4XH@1224|Proteobacteria	1224|Proteobacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase
CH3_k127_10834077_6	794903.OPIT5_03205	3.071e-91	306.0	COG0689@1|root,COG0689@2|Bacteria,46U55@74201|Verrucomicrobia,3K7EN@414999|Opitutae	414999|Opitutae	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
CH3_k127_10834077_11	1048339.KB913029_gene3814	2.827e-25	113.0	COG0406@1|root,COG0406@2|Bacteria,2HUBQ@201174|Actinobacteria	201174|Actinobacteria	G	Phosphoglycerate mutase family	-	-	5.4.2.12	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
CH3_k127_10834077_9	443143.GM18_0270	4.453e-43	170.0	COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,42NSS@68525|delta/epsilon subdivisions,2WIVV@28221|Deltaproteobacteria,43UAF@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
CH3_k127_10834077_12	903818.KI912268_gene3014	1.514e-18	99.0	COG1470@1|root,COG2931@1|root,COG1470@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,NPCBM_assoc
CH3_k127_10834077_13	1303518.CCALI_02036	7.49e-14	80.0	COG4969@1|root,COG4969@2|Bacteria	2|Bacteria	NU	cell adhesion	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,SBP_bac_10
CH3_k127_10834077_4	1038862.KB893840_gene976	4.121e-110	374.0	COG1696@1|root,COG1696@2|Bacteria,1MUXN@1224|Proteobacteria,2TRD1@28211|Alphaproteobacteria,3JYJ9@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	MBOAT, membrane-bound O-acyltransferase family	-	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
CH3_k127_10834077_2	1191523.MROS_1318	3.455e-132	440.0	COG0531@1|root,COG0531@2|Bacteria	2|Bacteria	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
CH3_k127_10834077_3	497964.CfE428DRAFT_6050	1.039e-116	382.0	COG0657@1|root,COG0657@2|Bacteria,46SRP@74201|Verrucomicrobia	74201|Verrucomicrobia	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
CH3_k127_10834077_7	794903.OPIT5_11905	8.803e-77	262.0	COG1704@1|root,COG1704@2|Bacteria,46V9M@74201|Verrucomicrobia,3K7DK@414999|Opitutae	414999|Opitutae	S	PFAM LemA family protein	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
CH3_k127_10853878_2	1110697.NCAST_36_00160	1.253e-19	94.0	COG0654@1|root,COG0654@2|Bacteria,2GIZU@201174|Actinobacteria,4FY7A@85025|Nocardiaceae	201174|Actinobacteria	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3,NAD_binding_8
CH3_k127_10853878_1	697282.Mettu_0535	8.823e-43	166.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
CH3_k127_10853878_0	756272.Plabr_0697	7.032e-45	175.0	2DBTJ@1|root,2ZAYX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
CH3_k127_10871_3	926550.CLDAP_13780	6.077e-50	186.0	COG2311@1|root,COG2311@2|Bacteria,2G8B7@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF418)	-	-	-	ko:K07148	-	-	-	-	ko00000	-	-	-	DUF418
CH3_k127_10871_0	497964.CfE428DRAFT_6439	1.787e-143	458.0	COG0413@1|root,COG0413@2|Bacteria	2|Bacteria	H	3-methyl-2-oxobutanoate hydroxymethyltransferase activity	-	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
CH3_k127_10871_1	497964.CfE428DRAFT_1804	2.735e-134	466.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,46UI8@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
CH3_k127_10871_2	497964.CfE428DRAFT_5731	1.73e-65	232.0	COG2197@1|root,COG2197@2|Bacteria,46UBU@74201|Verrucomicrobia	74201|Verrucomicrobia	T	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CH3_k127_10871_4	452637.Oter_1792	1.835e-08	55.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CH3_k127_10883118_3	1123242.JH636434_gene3758	1.977e-112	376.0	COG3537@1|root,COG3537@2|Bacteria,2J225@203682|Planctomycetes	203682|Planctomycetes	G	Glycosyl hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_92
CH3_k127_10883118_1	1267535.KB906767_gene1828	1.798e-282	889.0	COG3518@1|root,COG3518@2|Bacteria	2|Bacteria	S	anti-sigma factor antagonist activity	iraD	GO:0000988,GO:0000989,GO:0003674,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010605,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033554,GO:0042176,GO:0042177,GO:0043856,GO:0045893,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051248,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K11897,ko:K21637	-	M00334	-	-	ko00000,ko00002,ko02044	-	-	-	GPW_gp25
CH3_k127_10883118_2	497964.CfE428DRAFT_6180	7.407e-122	407.0	COG1520@1|root,COG1520@2|Bacteria,46THI@74201|Verrucomicrobia	2|Bacteria	S	SMART Pyrrolo-quinoline quinone	-	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
CH3_k127_10883118_10	189426.PODO_28355	1.864e-05	51.0	COG2805@1|root,COG2805@2|Bacteria,1TQ5F@1239|Firmicutes,4H9RK@91061|Bacilli,26QNT@186822|Paenibacillaceae	91061|Bacilli	NU	twitching motility protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
CH3_k127_10883118_5	485917.Phep_1253	2.321e-36	153.0	COG4409@1|root,COG4409@2|Bacteria,4P1PN@976|Bacteroidetes	976|Bacteroidetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
CH3_k127_10883118_6	679926.Mpet_1520	3.634e-26	112.0	arCOG03403@1|root,arCOG03403@2157|Archaea,2Y5T8@28890|Euryarchaeota	28890|Euryarchaeota	K	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
CH3_k127_10883118_8	1123242.JH636435_gene1245	1.869e-12	69.0	COG3391@1|root,COG3511@1|root,COG3391@2|Bacteria,COG3511@2|Bacteria,2IYNB@203682|Planctomycetes	203682|Planctomycetes	M	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase,Phosphoesterase
CH3_k127_10883118_0	1123242.JH636435_gene1245	0.0	1106.0	COG3391@1|root,COG3511@1|root,COG3391@2|Bacteria,COG3511@2|Bacteria,2IYNB@203682|Planctomycetes	203682|Planctomycetes	M	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase,Phosphoesterase
CH3_k127_10883118_4	1286632.P278_07760	2.167e-47	177.0	COG3345@1|root,COG3345@2|Bacteria,4PMM4@976|Bacteroidetes	976|Bacteroidetes	G	alpha-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_10884130_4	882083.SacmaDRAFT_5704	5.589e-34	142.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4DXJD@85010|Pseudonocardiales	201174|Actinobacteria	V	Daunorubicin resistance ABC transporter ATP-binding subunit	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
CH3_k127_10884130_0	314230.DSM3645_01876	1.831e-243	780.0	COG0308@1|root,COG0308@2|Bacteria,2IY5F@203682|Planctomycetes	203682|Planctomycetes	M	Peptidase M1, membrane alanine aminopeptidase	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	HEAT_2,Peptidase_M1
CH3_k127_10884130_5	378806.STAUR_7040	1.986e-26	118.0	COG0363@1|root,COG0363@2|Bacteria,1R5K6@1224|Proteobacteria,42UV6@68525|delta/epsilon subdivisions,2WP1R@28221|Deltaproteobacteria,2YVX1@29|Myxococcales	28221|Deltaproteobacteria	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	pgl	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
CH3_k127_10884130_1	497964.CfE428DRAFT_3605	6.003e-167	539.0	COG0364@1|root,COG0364@2|Bacteria,46SHX@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
CH3_k127_10884130_2	1499967.BAYZ01000164_gene6663	9.252e-151	491.0	COG0407@1|root,COG0407@2|Bacteria	2|Bacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
CH3_k127_10884130_3	1123073.KB899241_gene3060	7.058e-145	469.0	COG0477@1|root,COG2814@2|Bacteria,1MVKJ@1224|Proteobacteria,1RMHJ@1236|Gammaproteobacteria,1XDA0@135614|Xanthomonadales	135614|Xanthomonadales	EGP	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family	-	-	-	ko:K08137	-	-	-	-	ko00000,ko02000	2.A.1.1.1	-	-	Sugar_tr
CH3_k127_10886540_7	1121438.JNJA01000001_gene2525	0.0006343	43.0	COG0451@1|root,COG0451@2|Bacteria,1PB4Y@1224|Proteobacteria,42QBV@68525|delta/epsilon subdivisions,2WQ8F@28221|Deltaproteobacteria,2MB41@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
CH3_k127_10886540_1	652103.Rpdx1_1424	1.339e-132	430.0	COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,2TT5T@28211|Alphaproteobacteria,3JRQ2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46,4.2.1.76,5.1.3.2	ko:K01710,ko:K01784,ko:K12450	ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00362,M00632,M00793	R00291,R00293,R02984,R06513	RC00289,RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
CH3_k127_10886540_5	481448.Minf_2165	3.663e-12	75.0	2FHDV@1|root,34981@2|Bacteria,46W9B@74201|Verrucomicrobia,37GRP@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_10886540_4	1118054.CAGW01000014_gene225	4.437e-29	126.0	COG0350@1|root,COG0350@2|Bacteria,1VA03@1239|Firmicutes,4HETA@91061|Bacilli,26XF4@186822|Paenibacillaceae	91061|Bacilli	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	adaB	-	2.1.1.63	ko:K00567,ko:K10778,ko:K13531	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
CH3_k127_10886540_2	452637.Oter_1562	4.803e-109	368.0	COG2271@1|root,COG2271@2|Bacteria,46W2G@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Major Facilitator Superfamily	-	-	-	ko:K02445	-	-	-	-	ko00000,ko02000	2.A.1.4.3	-	-	MFS_1
CH3_k127_10886540_6	278957.ABEA03000069_gene3974	5.156e-05	53.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CH3_k127_10886540_0	1403819.BATR01000181_gene6235	1.933e-182	580.0	COG0162@1|root,COG0162@2|Bacteria,46UVG@74201|Verrucomicrobia,2ITSI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	tRNA synthetases class I (W and Y)	-	-	-	-	-	-	-	-	-	-	-	-	S4,tRNA-synt_1b
CH3_k127_10886540_3	196490.AUEZ01000020_gene629	2.084e-40	169.0	COG1749@1|root,COG1749@2|Bacteria,1QWWE@1224|Proteobacteria,2TX6F@28211|Alphaproteobacteria,3JUM6@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	N	Domain of unknown function (DUF4082)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4082,He_PIG
CH3_k127_10908147_6	1191523.MROS_1835	6.228e-08	54.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria	2|Bacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
CH3_k127_10908147_0	693746.OBV_03580	1.585e-66	242.0	COG1404@1|root,COG1404@2|Bacteria,1VD5C@1239|Firmicutes,24C2E@186801|Clostridia,2N8J1@216572|Oscillospiraceae	186801|Clostridia	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
CH3_k127_10908147_3	240016.ABIZ01000001_gene3530	8.186e-30	132.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,46TNN@74201|Verrucomicrobia,2ITZ4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
CH3_k127_10908147_5	278963.ATWD01000001_gene1092	3.137e-11	77.0	COG3250@1|root,COG3250@2|Bacteria,3Y3GV@57723|Acidobacteria,2JHVR@204432|Acidobacteriia	204432|Acidobacteriia	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4982,F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_64,Ig_3
CH3_k127_10908147_4	1303518.CCALI_01585	1.618e-19	90.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria	2|Bacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
CH3_k127_10908147_2	518766.Rmar_1378	2.358e-32	134.0	COG0526@1|root,COG0526@2|Bacteria,4NI00@976|Bacteroidetes	976|Bacteroidetes	CO	Pfam AhpC TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
CH3_k127_10908147_1	1396141.BATP01000022_gene383	1.459e-41	175.0	COG1595@1|root,COG1595@2|Bacteria,46TQ4@74201|Verrucomicrobia,2IVYP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4
CH3_k127_10908147_7	555779.Dthio_PD0141	6.752e-07	61.0	COG0438@1|root,COG1215@1|root,COG0438@2|Bacteria,COG1215@2|Bacteria,1MU5I@1224|Proteobacteria	1224|Proteobacteria	M	COG0463 Glycosyltransferases involved in cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CH3_k127_109213_2	497964.CfE428DRAFT_2770	1.811e-37	158.0	COG3071@1|root,COG3071@2|Bacteria	2|Bacteria	H	HemY protein	-	-	-	ko:K08309,ko:K11935,ko:K20543	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000,ko01011,ko02000	1.B.55.3	GH23	-	BCSC_C,TPR_12,TPR_16,TPR_19,TPR_6,TPR_8
CH3_k127_109213_1	1442599.JAAN01000005_gene1008	7.178e-101	342.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,1RPTA@1236|Gammaproteobacteria,1X46C@135614|Xanthomonadales	135614|Xanthomonadales	GM	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
CH3_k127_109213_0	382464.ABSI01000012_gene1959	2.826e-143	477.0	COG1086@1|root,COG1086@2|Bacteria,46UPP@74201|Verrucomicrobia,2IVCB@203494|Verrucomicrobiae	2|Bacteria	GM	Polysaccharide biosynthesis protein	capD	GO:0008150,GO:0043900,GO:0043902,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0065007,GO:1900190,GO:1900192	4.2.1.115,4.2.1.135,4.2.1.46	ko:K01710,ko:K15894,ko:K15912,ko:K19421	ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130	M00793	R06513,R09697	RC00402,RC02609	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding_3,Polysacc_synt_2
CH3_k127_109213_3	195253.Syn6312_1198	6.73e-23	101.0	COG2442@1|root,COG2442@2|Bacteria,1G8E6@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
CH3_k127_109213_4	96561.Dole_1009	2.32e-15	86.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,42MMR@68525|delta/epsilon subdivisions,2WJEB@28221|Deltaproteobacteria,2MJ3Q@213118|Desulfobacterales	28221|Deltaproteobacteria	GM	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
CH3_k127_10931788_1	1236514.BAKL01000065_gene4242	1.043e-112	376.0	COG0577@1|root,COG0577@2|Bacteria,4NEBD@976|Bacteroidetes,2FM6F@200643|Bacteroidia,4AND4@815|Bacteroidaceae	976|Bacteroidetes	V	Efflux ABC transporter, permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CH3_k127_10931788_0	575540.Isop_0300	6.616e-134	437.0	COG2382@1|root,COG2382@2|Bacteria,2IYMZ@203682|Planctomycetes	203682|Planctomycetes	P	Putative esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase
CH3_k127_10931788_2	1254432.SCE1572_04435	3.456e-62	224.0	COG1266@1|root,COG1668@1|root,COG1266@2|Bacteria,COG1668@2|Bacteria,1R3RG@1224|Proteobacteria,43B64@68525|delta/epsilon subdivisions,2X6JN@28221|Deltaproteobacteria,2YVQ4@29|Myxococcales	28221|Deltaproteobacteria	CP	sodium ABC transporter, permease	-	-	-	ko:K09696	ko02010,ko02020,map02010,map02020	M00253	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.115	-	-	ABC2_membrane_2,Abi
CH3_k127_10955258_5	195253.Syn6312_2251	2.499e-37	153.0	COG2730@1|root,COG2931@1|root,COG2730@2|Bacteria,COG2931@2|Bacteria,1G314@1117|Cyanobacteria,1H4DP@1129|Synechococcus	1117|Cyanobacteria	G	Glycosyl hydrolase family 9	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_2,Calx-beta,Glyco_hydro_9
CH3_k127_10955258_2	1123242.JH636434_gene3333	2.701e-110	368.0	COG4692@1|root,COG4692@2|Bacteria,2J06F@203682|Planctomycetes	203682|Planctomycetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
CH3_k127_10955258_3	236097.ADG881_1056	5.269e-57	210.0	COG4973@1|root,COG4973@2|Bacteria,1MUJJ@1224|Proteobacteria,1RMJG@1236|Gammaproteobacteria,1XIGP@135619|Oceanospirillales	135619|Oceanospirillales	L	Belongs to the 'phage' integrase family. XerC subfamily	xerC	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
CH3_k127_10955258_6	1131269.AQVV01000100_gene2556	2.734e-17	91.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
CH3_k127_10955258_1	243233.MCA2161	7.282e-167	549.0	COG3206@1|root,COG3206@2|Bacteria,1QX0J@1224|Proteobacteria,1RZ5A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	protein involved in exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_10955258_0	640081.Dsui_0821	0.0	1114.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,2VHUF@28216|Betaproteobacteria,2KUMN@206389|Rhodocyclales	206389|Rhodocyclales	L	DNA topoisomerase III	-	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim,Toprim_Crpt
CH3_k127_10955258_4	1396141.BATP01000056_gene3278	1.308e-50	204.0	COG0028@1|root,COG3055@1|root,COG3209@1|root,COG4625@1|root,COG4932@1|root,COG0028@2|Bacteria,COG3055@2|Bacteria,COG3209@2|Bacteria,COG4625@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	4.1.3.1	ko:K01637,ko:K20276	ko00630,ko01100,ko01110,ko01120,ko01200,ko02024,map00630,map01100,map01110,map01120,map01200,map02024	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	He_PIG,Laminin_G_3,Malectin
CH3_k127_10965289_3	761193.Runsl_3310	4.026e-56	206.0	COG0673@1|root,COG0673@2|Bacteria,4NGHJ@976|Bacteroidetes,47NH0@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CH3_k127_10965289_1	497964.CfE428DRAFT_4312	2.753e-98	330.0	COG1994@1|root,COG1994@2|Bacteria,46VEB@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50,Peptidase_M50B
CH3_k127_10965289_0	240016.ABIZ01000001_gene1668	7.811e-157	501.0	COG3239@1|root,COG3239@2|Bacteria,46SX7@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Fatty acid desaturase	desA	-	1.14.19.23,1.14.19.45	ko:K10255	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
CH3_k127_10965289_5	497964.CfE428DRAFT_6672	2e-22	100.0	COG0361@1|root,COG0361@2|Bacteria,46T5J@74201|Verrucomicrobia	74201|Verrucomicrobia	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
CH3_k127_10965289_4	497964.CfE428DRAFT_6673	6.665e-37	143.0	COG0724@1|root,COG0724@2|Bacteria,46VMU@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM RNP-1 like RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
CH3_k127_10965289_2	1268635.Loa_01459	3.522e-80	271.0	COG2094@1|root,COG2094@2|Bacteria,1RE0A@1224|Proteobacteria,1S9CM@1236|Gammaproteobacteria,1JD7P@118969|Legionellales	118969|Legionellales	L	Belongs to the DNA glycosylase MPG family	-	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
CH3_k127_10976344_2	555779.Dthio_PD3239	5.087e-142	458.0	COG1614@1|root,COG1614@2|Bacteria,1MVI5@1224|Proteobacteria,42N9A@68525|delta/epsilon subdivisions,2WK4H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit	-	-	2.3.1.169	ko:K14138	ko00720,ko01120,ko01200,map00720,map01120,map01200	M00377	R08433,R10243	RC00004,RC00113,RC01144,RC02963,RC02964,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhC
CH3_k127_10976344_3	237368.SCABRO_03345	5.117e-114	384.0	COG1456@1|root,COG1456@2|Bacteria,2J2CN@203682|Planctomycetes	203682|Planctomycetes	C	CO dehydrogenase/acetyl-CoA synthase delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	CdhD,FeS
CH3_k127_10976344_1	247490.KSU1_D0223	2.648e-156	515.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,2J2QB@203682|Planctomycetes	203682|Planctomycetes	C	Domain of unknown function (DUF4445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
CH3_k127_10976344_7	760568.Desku_1489	3.899e-55	201.0	COG3640@1|root,COG3640@2|Bacteria,1UZHR@1239|Firmicutes,24BYR@186801|Clostridia,260D8@186807|Peptococcaceae	186801|Clostridia	D	PFAM CobQ CobB MinD ParA nucleotide binding domain	cooC1	-	-	ko:K07321	-	-	-	-	ko00000	-	-	-	CbiA
CH3_k127_10976344_4	247490.KSU1_D0221	1.804e-99	334.0	COG2069@1|root,COG2069@2|Bacteria,2J2KV@203682|Planctomycetes	203682|Planctomycetes	C	CO dehydrogenase/acetyl-CoA synthase delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	CdhD
CH3_k127_10976344_6	574087.Acear_1299	8.383e-67	236.0	COG1410@1|root,COG1410@2|Bacteria,1VRVS@1239|Firmicutes,25EJA@186801|Clostridia	186801|Clostridia	E	PFAM dihydropteroate synthase, DHPS	acsE	-	2.1.1.13,2.1.1.258	ko:K00548,ko:K15023	ko00270,ko00450,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01230,map00270,map00450,map00670,map00720,map01100,map01110,map01120,map01200,map01230	M00017,M00377	R00946,R02289,R09365,R10243	RC00004,RC00035,RC00113,RC01144,RC01241,RC02871,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
CH3_k127_10976344_8	1540257.JQMW01000013_gene1215	2.28e-46	180.0	COG1810@1|root,COG1810@2|Bacteria,1V28Y@1239|Firmicutes,24DXC@186801|Clostridia,36DES@31979|Clostridiaceae	186801|Clostridia	S	Domain of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	DUF166
CH3_k127_10976344_5	42256.RradSPS_2576	2.03e-84	288.0	COG1526@1|root,COG1526@2|Bacteria,2GKWC@201174|Actinobacteria,4CQ2Z@84995|Rubrobacteria	84995|Rubrobacteria	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
CH3_k127_10976344_9	476272.RUMHYD_00357	1.593e-40	156.0	COG1905@1|root,COG1905@2|Bacteria,1V737@1239|Firmicutes,24I29@186801|Clostridia	186801|Clostridia	C	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit	nuoE	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
CH3_k127_10976344_0	1042877.GQS_04965	8.142e-237	752.0	COG1894@1|root,COG4231@1|root,arCOG01609@2157|Archaea,arCOG04537@2157|Archaea,2XUYN@28890|Euryarchaeota,243V2@183968|Thermococci	183968|Thermococci	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
CH3_k127_10976344_10	429009.Adeg_0334	3.415e-23	101.0	COG3383@1|root,COG3383@2|Bacteria,1UI1F@1239|Firmicutes,25EAG@186801|Clostridia,42J1I@68295|Thermoanaerobacterales	186801|Clostridia	C	NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding	-	-	1.17.1.10,1.6.5.3	ko:K00336,ko:K05299	ko00190,ko00680,ko00720,ko01100,ko01120,ko01200,map00190,map00680,map00720,map01100,map01120,map01200	M00144,M00377	R00134,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Fer4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
CH3_k127_10989166_0	314230.DSM3645_04800	3.683e-179	627.0	COG2373@1|root,COG2373@2|Bacteria,2IWRT@203682|Planctomycetes	203682|Planctomycetes	S	Large extracellular alpha-helical protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,A2M_comp,Thiol-ester_cl
CH3_k127_11001369_3	945713.IALB_1410	8.292e-18	85.0	COG2827@1|root,COG2827@2|Bacteria	2|Bacteria	L	Endonuclease containing a URI domain	yazA	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
CH3_k127_11001369_4	583355.Caka_2909	1.72e-09	60.0	COG4974@1|root,COG4974@2|Bacteria,46UB9@74201|Verrucomicrobia,3K9DD@414999|Opitutae	414999|Opitutae	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
CH3_k127_11001369_1	886293.Sinac_7584	8.599e-113	376.0	COG0715@1|root,COG0715@2|Bacteria,2IX2Y@203682|Planctomycetes	203682|Planctomycetes	P	Protein of unknown function (DUF3500)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3500
CH3_k127_11001369_0	1396418.BATQ01000113_gene4631	1.168e-118	392.0	COG1723@1|root,COG1723@2|Bacteria	2|Bacteria	S	PFAM Uncharacterised ACR, YagE family COG1723	yagE	-	-	-	-	-	-	-	-	-	-	-	DUF155
CH3_k127_11001369_2	1167006.UWK_02169	1.118e-32	144.0	COG1538@1|root,COG1538@2|Bacteria,1NQXF@1224|Proteobacteria,42ZDW@68525|delta/epsilon subdivisions,2WTVP@28221|Deltaproteobacteria,2MMSE@213118|Desulfobacterales	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
CH3_k127_11030557_14	1121013.P873_11445	6.444e-36	147.0	COG3677@1|root,COG3677@2|Bacteria,1MXYX@1224|Proteobacteria,1SZQR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	ISXO2-like transposase domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
CH3_k127_11030557_26	1120983.KB894574_gene1005	1.136e-14	79.0	COG3677@1|root,COG3677@2|Bacteria,1MXYX@1224|Proteobacteria,2TQR3@28211|Alphaproteobacteria,1JPHB@119043|Rhodobiaceae	28211|Alphaproteobacteria	L	Transposase zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
CH3_k127_11030557_20	1238450.VIBNISOn1_1470029	1.045e-28	128.0	COG3332@1|root,COG3332@2|Bacteria,1RE1W@1224|Proteobacteria,1S59Q@1236|Gammaproteobacteria,1XU3T@135623|Vibrionales	135623|Vibrionales	S	Transport and Golgi organisation 2	-	-	-	-	-	-	-	-	-	-	-	-	TANGO2
CH3_k127_11030557_4	1210884.HG799463_gene9621	6.845e-113	384.0	COG0189@1|root,COG0586@1|root,COG3332@1|root,COG0189@2|Bacteria,COG0586@2|Bacteria,COG3332@2|Bacteria	2|Bacteria	S	Transport and Golgi organisation 2	-	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	RimK,SNARE_assoc,TANGO2
CH3_k127_11030557_17	1123070.KB899257_gene2311	5.734e-33	134.0	COG2318@1|root,COG2318@2|Bacteria,46WF2@74201|Verrucomicrobia,2IWE9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_11030557_15	929703.KE386491_gene4207	1.745e-35	139.0	2C87P@1|root,32H7J@2|Bacteria,4NS7S@976|Bacteroidetes,47R39@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
CH3_k127_11030557_16	1502851.FG93_03399	1.271e-34	139.0	COG3350@1|root,COG3350@2|Bacteria,1N0GC@1224|Proteobacteria,2UBRM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	YHS domain protein	-	-	-	-	-	-	-	-	-	-	-	-	YHS
CH3_k127_11030557_6	864702.OsccyDRAFT_4593	1.054e-95	321.0	COG0580@1|root,COG0580@2|Bacteria,1G3MJ@1117|Cyanobacteria,1H9H5@1150|Oscillatoriales	1117|Cyanobacteria	G	Major intrinsic protein	-	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
CH3_k127_11030557_22	1123278.KB893444_gene1666	5.527e-25	115.0	2C87P@1|root,32H7J@2|Bacteria,4NS7S@976|Bacteroidetes,47R39@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
CH3_k127_11030557_18	382464.ABSI01000012_gene2101	3.503e-32	143.0	COG0526@1|root,COG4935@1|root,COG0526@2|Bacteria,COG4935@2|Bacteria,46UYI@74201|Verrucomicrobia,2IWE7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CH3_k127_11030557_11	382464.ABSI01000010_gene3251	1.716e-41	164.0	COG0526@1|root,COG3210@1|root,COG0526@2|Bacteria,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Omp28
CH3_k127_11030557_9	452637.Oter_0302	8.817e-68	238.0	COG5429@1|root,COG5429@2|Bacteria,46W7J@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF1223)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1223
CH3_k127_11030557_23	1185653.A1A1_08864	3.554e-18	98.0	COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HJN1@91061|Bacilli,26EYU@186818|Planococcaceae	91061|Bacilli	CO	COG0526 Thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CH3_k127_11030557_29	344747.PM8797T_01589	4.057e-06	58.0	COG3266@1|root,COG3266@2|Bacteria,2IZW5@203682|Planctomycetes	203682|Planctomycetes	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_11030557_2	861299.J421_1876	5.753e-184	594.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
CH3_k127_11030557_12	497964.CfE428DRAFT_5990	1.067e-38	153.0	COG1595@1|root,COG1595@2|Bacteria,46W20@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CH3_k127_11030557_25	1267534.KB906760_gene1563	9.717e-15	77.0	29A7N@1|root,2ZX8K@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_11030557_7	1396418.BATQ01000011_gene4474	1.535e-77	264.0	COG3576@1|root,COG3576@2|Bacteria,46SQM@74201|Verrucomicrobia,2IVR9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
CH3_k127_11030557_0	497964.CfE428DRAFT_5992	1.693e-294	923.0	COG3829@1|root,COG3829@2|Bacteria	2|Bacteria	T	transcription factor binding	-	-	-	ko:K15836	-	-	-	-	ko00000,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
CH3_k127_11030557_28	1230342.CTM_05128	1.647e-06	56.0	COG1145@1|root,32SB1@2|Bacteria,1V6N0@1239|Firmicutes,24M30@186801|Clostridia,36K6U@31979|Clostridiaceae	186801|Clostridia	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	DUF326
CH3_k127_11030557_13	861299.J421_1875	1.216e-37	149.0	COG0662@1|root,COG3193@1|root,COG0662@2|Bacteria,COG3193@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	ko:K11477	-	-	-	-	ko00000	-	-	-	Cupin_2,Haem_degrading
CH3_k127_11030557_21	1280001.BAOA01000100_gene4439	1.177e-28	127.0	COG3350@1|root,COG3350@2|Bacteria,1N0GC@1224|Proteobacteria,1S846@1236|Gammaproteobacteria,1XY38@135623|Vibrionales	135623|Vibrionales	S	YHS domain	-	-	-	-	-	-	-	-	-	-	-	-	YHS
CH3_k127_11030557_19	1502851.FG93_03399	8.668e-29	127.0	COG3350@1|root,COG3350@2|Bacteria,1N0GC@1224|Proteobacteria,2UBRM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	YHS domain protein	-	-	-	-	-	-	-	-	-	-	-	-	YHS
CH3_k127_11030557_5	211165.AJLN01000061_gene3947	4.918e-112	373.0	COG0346@1|root,COG0346@2|Bacteria,1G29P@1117|Cyanobacteria,1JK2A@1189|Stigonemataceae	1117|Cyanobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CH3_k127_11030557_10	489825.LYNGBM3L_01300	5.286e-45	172.0	29EN4@1|root,301K2@2|Bacteria,1G4I6@1117|Cyanobacteria,1HET5@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_11030557_3	504472.Slin_2526	5.12e-115	383.0	COG2146@1|root,COG2717@1|root,COG2146@2|Bacteria,COG2717@2|Bacteria,4NJUW@976|Bacteroidetes,47TAG@768503|Cytophagia	976|Bacteroidetes	P	Ferric reductase like transmembrane component	-	-	-	-	-	-	-	-	-	-	-	-	Ferric_reduct,Rieske
CH3_k127_11030557_27	489825.LYNGBM3L_01330	4.952e-14	75.0	2E14K@1|root,32WJQ@2|Bacteria,1G825@1117|Cyanobacteria,1HGGM@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_11030557_24	1077285.AGDG01000027_gene1673	4.877e-18	87.0	COG4828@1|root,COG4828@2|Bacteria,4NV5Z@976|Bacteroidetes,2G2GN@200643|Bacteroidia,4AVYR@815|Bacteroidaceae	976|Bacteroidetes	S	Protein of unknown function (DUF1622)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1622
CH3_k127_11030557_8	1403819.BATR01000054_gene1700	1.246e-72	249.0	COG0431@1|root,COG0431@2|Bacteria,46SXE@74201|Verrucomicrobia	74201|Verrucomicrobia	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
CH3_k127_11030557_1	211165.AJLN01000061_gene3942	1.036e-220	702.0	COG2303@1|root,COG2303@2|Bacteria,1G2DQ@1117|Cyanobacteria,1JHUA@1189|Stigonemataceae	1117|Cyanobacteria	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
CH3_k127_11030557_30	305700.B447_10758	0.0004922	51.0	2DU19@1|root,33NHC@2|Bacteria,1NKNM@1224|Proteobacteria,2VYQJ@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_11033080_16	395495.Lcho_0773	4.098e-05	46.0	COG3335@1|root,COG3335@2|Bacteria,1N5WI@1224|Proteobacteria,2VHUB@28216|Betaproteobacteria,1KPAP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
CH3_k127_11033080_13	1192868.CAIU01000040_gene4440	1.488e-08	56.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,43HGG@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	L	Recombinase zinc beta ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
CH3_k127_11033080_3	1121101.HMPREF1532_01876	1.033e-122	417.0	COG3525@1|root,COG3525@2|Bacteria,4NEQN@976|Bacteroidetes,2FVA6@200643|Bacteroidia,4AT0B@815|Bacteroidaceae	976|Bacteroidetes	G	Domain of unknown function (DUF4838)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4838
CH3_k127_11033080_10	880073.Calab_0674	4.083e-12	79.0	COG1520@1|root,COG2911@1|root,COG3420@1|root,COG1520@2|Bacteria,COG2911@2|Bacteria,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	4.2.2.3	ko:K01729,ko:K17713	ko00051,map00051	-	R03706	-	ko00000,ko00001,ko01000,ko02000	1.B.33.1	-	-	Beta_helix,Big_4,CHU_C,CarboxypepD_reg,DUF5050,HYR,Peptidase_S8,SprB
CH3_k127_11033080_14	497964.CfE428DRAFT_4678	5.101e-08	66.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	ko:K13735	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	Beta_helix,Big_2,CarboxypepD_reg,He_PIG,LysM,PSII_BNR,SLH,TIG,fn3
CH3_k127_11033080_2	452637.Oter_4539	4.704e-142	458.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
CH3_k127_11033080_7	621372.ACIH01000072_gene1944	1.748e-59	223.0	COG2942@1|root,COG2942@2|Bacteria,1TQMG@1239|Firmicutes,4HE7U@91061|Bacilli,26T2B@186822|Paenibacillaceae	91061|Bacilli	G	Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man)	rnbP	-	5.1.3.11	ko:K16213	-	-	R01445,R10810	RC00289	ko00000,ko01000	-	-	-	GlcNAc_2-epim
CH3_k127_11033080_9	1121957.ATVL01000006_gene2545	6.165e-50	184.0	COG1670@1|root,COG1670@2|Bacteria,4NMRH@976|Bacteroidetes,47QKT@768503|Cytophagia	976|Bacteroidetes	J	Domain of unknown function (DUF4202)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4202
CH3_k127_11033080_1	382464.ABSI01000005_gene1011	5.938e-162	526.0	COG1219@1|root,COG1219@2|Bacteria,46U7E@74201|Verrucomicrobia,2IVDM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	AAA domain (Cdc48 subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_2,ClpB_D2-small
CH3_k127_11033080_11	497964.CfE428DRAFT_6409	9.454e-11	68.0	COG3209@1|root,COG3209@2|Bacteria,46TI5@74201|Verrucomicrobia	74201|Verrucomicrobia	M	PFAM YD repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
CH3_k127_11033080_6	497964.CfE428DRAFT_6409	8.798e-99	345.0	COG3209@1|root,COG3209@2|Bacteria,46TI5@74201|Verrucomicrobia	74201|Verrucomicrobia	M	PFAM YD repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
CH3_k127_11033080_12	1499967.BAYZ01000095_gene4080	4.015e-10	70.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Peptidase_C39,RHS_repeat
CH3_k127_11033080_4	926550.CLDAP_07020	2.27e-115	377.0	COG3293@1|root,COG3293@2|Bacteria,2G7YC@200795|Chloroflexi	200795|Chloroflexi	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
CH3_k127_11033080_8	240016.ABIZ01000001_gene5629	3.35e-58	211.0	COG2912@1|root,COG2912@2|Bacteria	2|Bacteria	P	Transglutaminase-like superfamily	CP_0628	-	-	-	-	-	-	-	-	-	-	-	TPR_9,Transglut_core2,VIT
CH3_k127_11033080_15	349741.Amuc_0982	7.096e-07	59.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	DNase_NucA_NucB,Endonuclea_NS_2,RHS_repeat
CH3_k127_11033080_0	583355.Caka_3117	7.73e-215	697.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Beta_helix,DUF1565
CH3_k127_11033080_5	886293.Sinac_0920	2.169e-107	364.0	COG0673@1|root,COG0673@2|Bacteria,2IWZW@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CH3_k127_11057103_2	1396141.BATP01000023_gene554	1.112e-108	373.0	COG2340@1|root,COG2340@2|Bacteria,46VC3@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
CH3_k127_11057103_5	177439.DP0005	6.157e-99	329.0	COG0106@1|root,COG0106@2|Bacteria,1R6J2@1224|Proteobacteria,43B0N@68525|delta/epsilon subdivisions,2X6EQ@28221|Deltaproteobacteria,2MICV@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Belongs to the HisA HisF family	-	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
CH3_k127_11057103_3	290397.Adeh_1677	1.483e-101	345.0	COG1055@1|root,COG1055@2|Bacteria,1NEVR@1224|Proteobacteria,42NU5@68525|delta/epsilon subdivisions,2WJV4@28221|Deltaproteobacteria,2YX9Q@29|Myxococcales	28221|Deltaproteobacteria	P	Arsenical pump membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
CH3_k127_11057103_6	1123229.AUBC01000001_gene1837	1.421e-35	144.0	2E61B@1|root,330QK@2|Bacteria,1N39M@1224|Proteobacteria,2U8C9@28211|Alphaproteobacteria,3JZ9V@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_11057103_1	452637.Oter_0253	8.059e-147	474.0	COG1454@1|root,COG1454@2|Bacteria	2|Bacteria	C	hydroxyacid-oxoacid transhydrogenase activity	CT0951	-	1.1.1.1,4.3.3.7	ko:K00001,ko:K01714	ko00010,ko00071,ko00261,ko00300,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,ko01230,map00010,map00071,map00261,map00300,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220,map01230	M00016,M00525,M00526,M00527	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310,R10147	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273,RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	Fe-ADH
CH3_k127_11057103_0	342610.Patl_0129	6.683e-192	616.0	COG0591@1|root,COG0591@2|Bacteria,1PNHU@1224|Proteobacteria,1S0S6@1236|Gammaproteobacteria,2Q4RI@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
CH3_k127_11057103_4	794903.OPIT5_04755	5.555e-100	332.0	COG2152@1|root,COG2152@2|Bacteria,46YKJ@74201|Verrucomicrobia,3K8SE@414999|Opitutae	2|Bacteria	G	beta-1,4-mannooligosaccharide phosphorylase	-	-	2.4.1.339,2.4.1.340	ko:K20885	-	-	R11397,R11398	RC00049,RC02748	ko00000,ko01000	-	GH130	-	Glyco_hydro_130
CH3_k127_11065073_2	742727.HMPREF9447_03877	8.51e-15	79.0	COG2006@1|root,COG2006@2|Bacteria,4P0ZM@976|Bacteroidetes,2FR0W@200643|Bacteroidia,4APQE@815|Bacteroidaceae	976|Bacteroidetes	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
CH3_k127_11065073_4	1051985.l11_21780	1.662e-10	70.0	COG0863@1|root,COG0863@2|Bacteria,1R4QN@1224|Proteobacteria,2VP1E@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.113	ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Mrr_N,N6_N4_Mtase
CH3_k127_11065073_3	1123242.JH636435_gene1423	2.775e-13	80.0	COG4968@1|root,COG4968@2|Bacteria,2IZKQ@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CH3_k127_11065073_1	744872.Spica_1624	5.066e-37	148.0	COG0187@1|root,COG0187@2|Bacteria,2J6PT@203691|Spirochaetes	203691|Spirochaetes	L	DNA topoisomerase	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
CH3_k127_11065073_0	1121957.ATVL01000014_gene1459	1.708e-142	493.0	COG5563@1|root,COG5563@2|Bacteria,4PHUI@976|Bacteroidetes,47VHU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_11071954_5	1123508.JH636444_gene5158	4.132e-11	75.0	COG2165@1|root,COG2165@2|Bacteria,2IZG4@203682|Planctomycetes	203682|Planctomycetes	NU	TIGRFAM prepilin-type N-terminal cleavage methylation domain	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CH3_k127_11071954_4	243090.RB7746	3.363e-11	68.0	COG3119@1|root,COG3119@2|Bacteria,2J2HN@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase activity	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
CH3_k127_11071954_1	1267535.KB906767_gene952	2.214e-155	505.0	COG0673@1|root,COG0673@2|Bacteria,3Y65Y@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CH3_k127_11071954_2	589865.DaAHT2_0883	6.02e-18	90.0	COG0824@1|root,COG0824@2|Bacteria,1PEBE@1224|Proteobacteria,42TIA@68525|delta/epsilon subdivisions,2WQ9X@28221|Deltaproteobacteria,2MMDF@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
CH3_k127_11071954_3	515635.Dtur_1559	2.792e-17	87.0	COG0071@1|root,COG0071@2|Bacteria	2|Bacteria	O	Belongs to the small heat shock protein (HSP20) family	MA20_45160	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
CH3_k127_11071954_0	309799.DICTH_1451	1.362e-263	834.0	COG0466@1|root,COG0466@2|Bacteria	2|Bacteria	O	ATP-dependent peptidase activity	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
CH3_k127_11071954_6	349741.Amuc_1499	0.000126	52.0	COG3026@1|root,COG3026@2|Bacteria,46W95@74201|Verrucomicrobia,2IUUR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
CH3_k127_110753_2	574087.Acear_1032	3.193e-18	88.0	COG0283@1|root,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,24HEF@186801|Clostridia,3WAMU@53433|Halanaerobiales	186801|Clostridia	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
CH3_k127_110753_0	2903.EOD40718	1.551e-124	416.0	COG0169@1|root,KOG0692@2759|Eukaryota	2759|Eukaryota	E	shikimate 3-dehydrogenase (NADP+) activity	-	GO:0003674,GO:0003824,GO:0003866,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0071704,GO:1901576	2.5.1.19,2.7.1.160	ko:K00800,ko:K10669	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	EPSP_synthase
CH3_k127_110753_1	429009.Adeg_1150	1.513e-57	212.0	COG0287@1|root,COG0287@2|Bacteria,1TPXG@1239|Firmicutes,248KX@186801|Clostridia,42GDJ@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM Prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDH
CH3_k127_110753_3	1411685.U062_00848	4.059e-17	87.0	COG2968@1|root,COG2968@2|Bacteria,1RC2K@1224|Proteobacteria,1S244@1236|Gammaproteobacteria,1J5RA@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF541)	-	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
CH3_k127_11112291_2	1100721.ALKO01000032_gene173	4.51e-19	92.0	COG3668@1|root,COG3668@2|Bacteria,1N73M@1224|Proteobacteria,2VXUM@28216|Betaproteobacteria	28216|Betaproteobacteria	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
CH3_k127_11112291_1	452637.Oter_4174	2.76e-60	214.0	COG1595@1|root,COG1595@2|Bacteria,46VAN@74201|Verrucomicrobia	74201|Verrucomicrobia	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
CH3_k127_11112291_0	452637.Oter_2424	2.59e-86	293.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,46VB0@74201|Verrucomicrobia,3K8AK@414999|Opitutae	414999|Opitutae	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CH3_k127_11116034_8	794903.OPIT5_27940	1.739e-59	218.0	COG1595@1|root,COG1595@2|Bacteria,46YS4@74201|Verrucomicrobia,3K8W5@414999|Opitutae	414999|Opitutae	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
CH3_k127_11116034_6	497964.CfE428DRAFT_2981	1.162e-103	370.0	COG0515@1|root,COG0515@2|Bacteria,46U28@74201|Verrucomicrobia	74201|Verrucomicrobia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF1648,DUF4019,Pkinase
CH3_k127_11116034_18	886293.Sinac_4894	1.987e-20	108.0	COG1595@1|root,COG1595@2|Bacteria,2J3UT@203682|Planctomycetes	203682|Planctomycetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CH3_k127_11116034_14	886293.Sinac_4894	3.187e-33	142.0	COG1595@1|root,COG1595@2|Bacteria,2J3UT@203682|Planctomycetes	203682|Planctomycetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CH3_k127_11116034_15	886293.Sinac_4894	1.038e-32	132.0	COG1595@1|root,COG1595@2|Bacteria,2J3UT@203682|Planctomycetes	203682|Planctomycetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CH3_k127_11116034_4	344747.PM8797T_32395	3.065e-114	389.0	COG0793@1|root,COG0793@2|Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S41,Tricorn_C1
CH3_k127_11116034_10	547042.BACCOPRO_00511	4.465e-50	201.0	COG2819@1|root,COG2819@2|Bacteria,4NGJB@976|Bacteroidetes,2FR8R@200643|Bacteroidia,4AQA2@815|Bacteroidaceae	976|Bacteroidetes	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
CH3_k127_11116034_20	1502850.FG91_00796	1.837e-06	61.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,1R5P1@1224|Proteobacteria,2U0ZV@28211|Alphaproteobacteria,2KEB5@204457|Sphingomonadales	204457|Sphingomonadales	QU	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
CH3_k127_11116034_7	1410653.JHVC01000018_gene2284	6.566e-95	329.0	COG1404@1|root,COG1404@2|Bacteria,1VD5C@1239|Firmicutes,24C2E@186801|Clostridia,36H8D@31979|Clostridiaceae	186801|Clostridia	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
CH3_k127_11116034_9	929703.KE386491_gene2889	3.212e-55	199.0	COG0154@1|root,COG0154@2|Bacteria,4NF8C@976|Bacteroidetes,47KZQ@768503|Cytophagia	976|Bacteroidetes	J	Amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
CH3_k127_11116034_2	1123277.KB893211_gene4412	1.117e-130	438.0	COG4409@1|root,COG4409@2|Bacteria,4NIJX@976|Bacteroidetes,47MH2@768503|Cytophagia	976|Bacteroidetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
CH3_k127_11116034_0	1396141.BATP01000005_gene6065	1.094e-189	622.0	COG0272@1|root,COG0272@2|Bacteria,46TMK@74201|Verrucomicrobia,2ITPR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	-	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
CH3_k127_11116034_19	395494.Galf_1566	2.18e-15	78.0	COG0790@1|root,COG3087@1|root,COG0790@2|Bacteria,COG3087@2|Bacteria,1MWPA@1224|Proteobacteria,2VM3A@28216|Betaproteobacteria	28216|Betaproteobacteria	KLT	PFAM Sel1 domain protein repeat-containing protein	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	SPOR,Sel1
CH3_k127_11116034_3	156889.Mmc1_2003	1.339e-130	430.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2TR2B@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Sel1 domain protein repeat-containing protein	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
CH3_k127_11116034_16	867903.ThesuDRAFT_02283	2.717e-30	128.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,248AX@186801|Clostridia,3WCD6@538999|Clostridiales incertae sedis	186801|Clostridia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
CH3_k127_11116034_11	313628.LNTAR_20703	2.783e-39	166.0	COG3147@1|root,COG3147@2|Bacteria	2|Bacteria	S	peptidoglycan binding	-	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DUF3108,SPOR
CH3_k127_11116034_21	383372.Rcas_3764	7.552e-06	58.0	COG1277@1|root,COG1277@2|Bacteria,2G79P@200795|Chloroflexi	200795|Chloroflexi	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
CH3_k127_11116034_5	313628.LNTAR_12676	1.163e-109	367.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	pilH	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CH3_k127_11116034_1	313628.LNTAR_12671	4.539e-185	600.0	COG2217@1|root,COG2217@2|Bacteria	2|Bacteria	P	Heavy metal translocating P-type atpase	cadA	-	3.6.3.3,3.6.3.5,3.6.3.54	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5,3.A.3.6	-	-	E1-E2_ATPase,Hydrolase
CH3_k127_11116034_17	1125863.JAFN01000001_gene727	1.726e-27	125.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,42NUT@68525|delta/epsilon subdivisions,2WKQX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
CH3_k127_11116034_13	1487923.DP73_10970	1.05e-33	141.0	COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,248MP@186801|Clostridia	186801|Clostridia	O	SPFH Band 7 PHB domain protein	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
CH3_k127_11116034_12	1142394.PSMK_15610	1.492e-38	163.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
CH3_k127_11122327_61	74547.PMT_1528	0.0006697	45.0	COG0532@1|root,COG3266@1|root,COG0532@2|Bacteria,COG3266@2|Bacteria,1G1WQ@1117|Cyanobacteria,1MKJQ@1212|Prochloraceae	1117|Cyanobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
CH3_k127_11122327_13	497964.CfE428DRAFT_1789	1.365e-148	482.0	COG0195@1|root,COG0195@2|Bacteria,46TRP@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
CH3_k127_11122327_49	247490.KSU1_C0931	1.21e-21	98.0	COG1278@1|root,COG1278@2|Bacteria	2|Bacteria	K	Cold shock	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
CH3_k127_11122327_31	264732.Moth_0582	2.527e-79	280.0	COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,247P8@186801|Clostridia,42F9T@68295|Thermoanaerobacterales	186801|Clostridia	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
CH3_k127_11122327_10	497964.CfE428DRAFT_3913	1.857e-167	538.0	COG3119@1|root,COG3119@2|Bacteria,46TFH@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CH3_k127_11122327_32	404589.Anae109_0137	1.854e-74	269.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,42NA4@68525|delta/epsilon subdivisions,2WNXT@28221|Deltaproteobacteria,2YV4W@29|Myxococcales	28221|Deltaproteobacteria	EGP	of the major facilitator superfamily	agmP	-	-	ko:K08151	-	M00668	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75	-	-	MFS_1,MFS_1_like,Sugar_tr
CH3_k127_11122327_36	909663.KI867150_gene1086	2.353e-64	231.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42N8J@68525|delta/epsilon subdivisions,2WK63@28221|Deltaproteobacteria,2MRGY@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CH3_k127_11122327_58	1396141.BATP01000023_gene664	1.02e-10	73.0	COG2931@1|root,COG3266@1|root,COG4733@1|root,COG4932@1|root,COG2931@2|Bacteria,COG3266@2|Bacteria,COG4733@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K20541	-	-	-	-	ko00000,ko02000	4.D.3.1.6	-	-	BcsB,DUF1499,Flg_new
CH3_k127_11122327_37	1042375.AFPL01000055_gene2315	2.289e-61	222.0	COG2197@1|root,COG2197@2|Bacteria,1R9GN@1224|Proteobacteria,1SYQY@1236|Gammaproteobacteria,467K2@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	helix_turn_helix, Lux Regulon	nreC	-	-	ko:K07684	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
CH3_k127_11122327_8	1131269.AQVV01000050_gene421	2.432e-181	580.0	COG0305@1|root,COG0305@2|Bacteria	2|Bacteria	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
CH3_k127_11122327_11	1156937.MFUM_230019	1.592e-158	530.0	COG4775@1|root,COG4775@2|Bacteria,46S5F@74201|Verrucomicrobia,37GCF@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	Surface antigen	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
CH3_k127_11122327_19	247490.KSU1_C0714	2.813e-128	454.0	COG1404@1|root,COG1404@2|Bacteria,2IZNN@203682|Planctomycetes	203682|Planctomycetes	O	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
CH3_k127_11122327_57	1123278.KB893617_gene3377	3.875e-13	84.0	COG4447@1|root,COG4447@2|Bacteria,4NESU@976|Bacteroidetes,47NMF@768503|Cytophagia	976|Bacteroidetes	G	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CH3_k127_11122327_56	497964.CfE428DRAFT_4704	1.635e-14	82.0	COG2825@1|root,COG2825@2|Bacteria,46T22@74201|Verrucomicrobia	74201|Verrucomicrobia	M	PFAM outer membrane chaperone Skp (OmpH)	hlpA	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
CH3_k127_11122327_7	497964.CfE428DRAFT_6478	3.524e-187	593.0	COG1453@1|root,COG1453@2|Bacteria,46S6J@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Aldo/keto reductase family	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red
CH3_k127_11122327_46	497964.CfE428DRAFT_6673	4.667e-27	113.0	COG0724@1|root,COG0724@2|Bacteria,46VMU@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM RNP-1 like RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
CH3_k127_11122327_17	1288963.ADIS_2835	3.35e-131	435.0	COG3356@1|root,COG3356@2|Bacteria,4NH6U@976|Bacteroidetes,47NFZ@768503|Cytophagia	976|Bacteroidetes	S	PFAM Neutral alkaline nonlysosomal ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
CH3_k127_11122327_14	478741.JAFS01000001_gene1976	5.104e-147	475.0	COG0798@1|root,COG0798@2|Bacteria,46UD3@74201|Verrucomicrobia,37FUU@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	P	Sodium Bile acid symporter family	-	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
CH3_k127_11122327_43	794903.OPIT5_06500	1.313e-31	141.0	COG0640@1|root,COG0640@2|Bacteria,46WF9@74201|Verrucomicrobia,3K8BI@414999|Opitutae	414999|Opitutae	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
CH3_k127_11122327_22	1163617.SCD_n02152	7.671e-105	346.0	COG0500@1|root,COG2226@2|Bacteria,1MVXN@1224|Proteobacteria,2VQVG@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Methyltransferase type 11	arsM	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
CH3_k127_11122327_40	497964.CfE428DRAFT_5842	1.027e-49	181.0	COG1595@1|root,COG1595@2|Bacteria,46W91@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CH3_k127_11122327_35	926550.CLDAP_10330	5.475e-68	238.0	COG0328@1|root,COG0328@2|Bacteria,2G6PS@200795|Chloroflexi	200795|Chloroflexi	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	Cauli_VI,RNase_H
CH3_k127_11122327_42	880072.Desac_0616	1.257e-34	145.0	COG2856@1|root,COG2856@2|Bacteria	2|Bacteria	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,Peptidase_M78
CH3_k127_11122327_52	1220534.B655_1532	4.486e-21	102.0	COG0655@1|root,arCOG02573@2157|Archaea,2XVMU@28890|Euryarchaeota,23PMW@183925|Methanobacteria	183925|Methanobacteria	S	PFAM NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
CH3_k127_11122327_23	909663.KI867150_gene1425	4.238e-97	325.0	COG4232@1|root,COG4232@2|Bacteria,1PK9S@1224|Proteobacteria,42PV0@68525|delta/epsilon subdivisions,2WJPK@28221|Deltaproteobacteria,2MS43@213462|Syntrophobacterales	28221|Deltaproteobacteria	CO	PFAM cytochrome c biogenesis protein, transmembrane region	dsbD	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
CH3_k127_11122327_44	909663.KI867150_gene1424	6.745e-31	138.0	COG0526@1|root,COG0526@2|Bacteria,1N0R9@1224|Proteobacteria,42UD9@68525|delta/epsilon subdivisions,2WQ0H@28221|Deltaproteobacteria,2MQPG@213462|Syntrophobacterales	28221|Deltaproteobacteria	CO	Thioredoxin	trx-2	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
CH3_k127_11122327_53	1499967.BAYZ01000050_gene2842	6.486e-20	91.0	COG0526@1|root,COG0526@2|Bacteria,2NQ71@2323|unclassified Bacteria	2|Bacteria	CO	Thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4369,Thioredoxin_3
CH3_k127_11122327_9	595460.RRSWK_03127	1.26e-167	537.0	COG0701@1|root,COG0701@2|Bacteria,2J0GE@203682|Planctomycetes	203682|Planctomycetes	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
CH3_k127_11122327_48	706587.Desti_5389	8.152e-22	99.0	COG0640@1|root,COG0640@2|Bacteria,1MZT1@1224|Proteobacteria,42V3T@68525|delta/epsilon subdivisions,2WS3M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	regulatory protein, arsR	-	-	-	ko:K03892,ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
CH3_k127_11122327_25	452637.Oter_2551	2.383e-96	326.0	COG5002@1|root,COG5002@2|Bacteria,46SSA@74201|Verrucomicrobia,3K7XI@414999|Opitutae	414999|Opitutae	T	Histidine kinase	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
CH3_k127_11122327_28	452637.Oter_2550	2.84e-84	291.0	COG0745@1|root,COG0745@2|Bacteria,46SS3@74201|Verrucomicrobia,3K7XM@414999|Opitutae	414999|Opitutae	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CH3_k127_11122327_34	452637.Oter_2549	7.415e-70	243.0	COG0704@1|root,COG0704@2|Bacteria,46SUX@74201|Verrucomicrobia,3K824@414999|Opitutae	414999|Opitutae	P	Plays a role in the regulation of phosphate uptake	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
CH3_k127_11122327_20	903818.KI912268_gene980	2.917e-114	374.0	COG1117@1|root,COG1117@2|Bacteria,3Y35A@57723|Acidobacteria	57723|Acidobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
CH3_k127_11122327_24	1242864.D187_004631	7.417e-97	338.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,42MWK@68525|delta/epsilon subdivisions,2WJKH@28221|Deltaproteobacteria,2YVAR@29|Myxococcales	28221|Deltaproteobacteria	P	Phosphate transport system permease	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,DUF3333
CH3_k127_11122327_30	290397.Adeh_4005	1.593e-82	289.0	COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,42N2N@68525|delta/epsilon subdivisions,2WJJ1@28221|Deltaproteobacteria,2YV6J@29|Myxococcales	28221|Deltaproteobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
CH3_k127_11122327_29	290397.Adeh_4006	1.1e-82	284.0	COG0226@1|root,COG0226@2|Bacteria,1MVXP@1224|Proteobacteria,42P0G@68525|delta/epsilon subdivisions,2WK7Y@28221|Deltaproteobacteria,2YVQ5@29|Myxococcales	28221|Deltaproteobacteria	P	PBP superfamily domain	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
CH3_k127_11122327_26	247634.GPB2148_1563	5.451e-88	304.0	COG3746@1|root,COG3746@2|Bacteria,1NT6B@1224|Proteobacteria,1SM5C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
CH3_k127_11122327_27	344747.PM8797T_29862	2.264e-84	291.0	COG1082@1|root,COG1082@2|Bacteria,2J0ZG@203682|Planctomycetes	203682|Planctomycetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CH3_k127_11122327_18	661478.OP10G_0861	6.753e-131	429.0	COG2730@1|root,COG2730@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase
CH3_k127_11122327_0	1123242.JH636435_gene1197	1.505e-275	860.0	COG3119@1|root,COG3119@2|Bacteria,2IXWN@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CH3_k127_11122327_5	240016.ABIZ01000001_gene5457	2.934e-214	675.0	COG3119@1|root,COG3119@2|Bacteria,46U45@74201|Verrucomicrobia,2IV5A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CH3_k127_11122327_4	521674.Plim_1566	2.28e-223	710.0	COG1413@1|root,COG3119@1|root,COG1413@2|Bacteria,COG3119@2|Bacteria,2IYFZ@203682|Planctomycetes	203682|Planctomycetes	CP	COG3119 Arylsulfatase A	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
CH3_k127_11122327_2	1123242.JH636435_gene1179	1.225e-260	811.0	COG3119@1|root,COG3119@2|Bacteria,2IXHT@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CH3_k127_11122327_1	595460.RRSWK_04657	4.459e-272	844.0	COG3119@1|root,COG3119@2|Bacteria,2IWVY@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
CH3_k127_11122327_15	62928.azo2300	9.391e-139	452.0	COG1055@1|root,COG1055@2|Bacteria,1N68M@1224|Proteobacteria,2VH3A@28216|Betaproteobacteria,2KVZG@206389|Rhodocyclales	206389|Rhodocyclales	P	Putative Na+/H+ antiporter	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiport_3
CH3_k127_11122327_3	497964.CfE428DRAFT_4597	3.24e-231	726.0	COG4108@1|root,COG4108@2|Bacteria,46SF9@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
CH3_k127_11122327_12	483219.LILAB_30160	1.091e-154	498.0	COG2059@1|root,COG2059@2|Bacteria,1MUBW@1224|Proteobacteria,42QCN@68525|delta/epsilon subdivisions,2WIYT@28221|Deltaproteobacteria,2YV4K@29|Myxococcales	28221|Deltaproteobacteria	P	Chromate transporter	chrA	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
CH3_k127_11122327_59	164757.Mjls_1689	5.617e-09	64.0	COG3583@1|root,COG3666@1|root,COG3583@2|Bacteria,COG3666@2|Bacteria,2H4RU@201174|Actinobacteria,235V0@1762|Mycobacteriaceae	201174|Actinobacteria	L	Resuscitation-promoting factor rpfB	rpfB	-	-	ko:K21688	-	-	-	-	ko00000	-	-	-	DUF348,G5,Transglycosylas
CH3_k127_11122327_54	794903.OPIT5_13650	7.066e-20	103.0	2AXAG@1|root,30YNX@2|Bacteria,46YVC@74201|Verrucomicrobia,3K96I@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_11122327_38	485918.Cpin_0414	1.841e-60	212.0	COG1490@1|root,COG1490@2|Bacteria,4NNFF@976|Bacteroidetes,1ISI6@117747|Sphingobacteriia	976|Bacteroidetes	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
CH3_k127_11122327_60	1379698.RBG1_1C00001G0366	1.748e-06	60.0	COG3292@1|root,COG3292@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K16923	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.28	-	-	Reg_prop,Y_Y_Y
CH3_k127_11122327_33	583355.Caka_1736	1.747e-71	278.0	COG2312@1|root,COG2312@2|Bacteria,46TMX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
CH3_k127_11122327_16	382464.ABSI01000013_gene1549	7.43e-137	494.0	COG2312@1|root,COG3211@1|root,COG2312@2|Bacteria,COG3211@2|Bacteria,46XD5@74201|Verrucomicrobia,2IVHX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Fn3_assoc,LTD
CH3_k127_11122327_50	1396141.BATP01000030_gene3719	1.627e-21	113.0	COG3119@1|root,COG3211@1|root,COG3656@1|root,COG5337@1|root,COG3119@2|Bacteria,COG3211@2|Bacteria,COG3656@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	phoX	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	CotH,DUF839
CH3_k127_11122327_41	1396141.BATP01000022_gene383	1.769e-49	195.0	COG1595@1|root,COG1595@2|Bacteria,46TQ4@74201|Verrucomicrobia,2IVYP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4
CH3_k127_11122327_47	382464.ABSI01000006_gene874	6.67e-25	112.0	COG1595@1|root,COG1595@2|Bacteria,46XM2@74201|Verrucomicrobia,2IW65@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
CH3_k127_11122327_6	1156937.MFUM_90002	4.897e-194	617.0	COG0034@1|root,COG0034@2|Bacteria,46SSU@74201|Verrucomicrobia,37G3Z@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7
CH3_k127_11122327_21	861299.J421_2088	1.098e-105	362.0	COG0719@1|root,COG0719@2|Bacteria,1ZSTG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
CH3_k127_11135627_0	1122917.KB899660_gene1499	3.038e-106	360.0	COG3420@1|root,COG4225@1|root,COG3420@2|Bacteria,COG4225@2|Bacteria	2|Bacteria	S	unsaturated chondroitin disaccharide hydrolase activity	-	-	5.1.3.37	ko:K01795	ko00051,map00051	-	R08693	RC00509	ko00000,ko00001,ko01000	-	-	-	Beta_helix,DUF1735,DUF4962,F5_F8_type_C,Hepar_II_III,Laminin_G_3,SLH
CH3_k127_11135627_2	497964.CfE428DRAFT_6252	2.297e-82	285.0	COG1968@1|root,COG1968@2|Bacteria,46SP6@74201|Verrucomicrobia	74201|Verrucomicrobia	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
CH3_k127_11135627_1	497964.CfE428DRAFT_1213	7.016e-105	351.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	DUF4388,HATPase_c,HTH_8,HisKA,Response_reg,SSF,Sigma54_activat
CH3_k127_11144437_12	595460.RRSWK_04778	5.031e-09	60.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2IXZY@203682|Planctomycetes	203682|Planctomycetes	T	COG0515 Serine threonine protein	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_10,TPR_12,TPR_8
CH3_k127_11144437_4	861299.J421_5620	9.301e-70	246.0	28J3W@1|root,2Z900@2|Bacteria	2|Bacteria	S	NIPSNAP family containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NIPSNAP
CH3_k127_11144437_3	448385.sce3153	3.265e-90	302.0	COG0670@1|root,COG0670@2|Bacteria,1R7VN@1224|Proteobacteria,43DVQ@68525|delta/epsilon subdivisions,2WZ04@28221|Deltaproteobacteria,2Z11K@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the BI1 family	-	-	-	ko:K06890	-	-	-	-	ko00000	-	-	-	Bax1-I
CH3_k127_11144437_8	94122.Shewana3_0285	2.452e-12	69.0	COG0401@1|root,COG0401@2|Bacteria,1N7K3@1224|Proteobacteria,1SGD5@1236|Gammaproteobacteria,2QCT8@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Proteolipid membrane potential modulator	-	-	-	-	-	-	-	-	-	-	-	-	Pmp3
CH3_k127_11144437_1	278957.ABEA03000091_gene714	6.855e-111	365.0	COG0708@1|root,COG0708@2|Bacteria,46TGT@74201|Verrucomicrobia,3K7VW@414999|Opitutae	414999|Opitutae	L	exodeoxyribonuclease III	-	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
CH3_k127_11144437_0	1396418.BATQ01000078_gene592	3.792e-155	499.0	COG0620@1|root,COG0620@2|Bacteria,46W8R@74201|Verrucomicrobia,2IWM7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Cobalamin-independent synthase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Meth_synt_2
CH3_k127_11144437_2	1185876.BN8_00813	2.48e-108	358.0	COG2220@1|root,COG2220@2|Bacteria,4PJJ0@976|Bacteroidetes,47NNW@768503|Cytophagia	976|Bacteroidetes	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
CH3_k127_11144437_13	682795.AciX8_1050	2.364e-06	59.0	2C730@1|root,32UQY@2|Bacteria,3Y59Z@57723|Acidobacteria,2JJP2@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_11144437_5	497964.CfE428DRAFT_1749	1.921e-46	171.0	COG0316@1|root,COG0316@2|Bacteria,46T1T@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Belongs to the HesB IscA family	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
CH3_k127_11144437_9	330214.NIDE4027	7.203e-11	70.0	COG1076@1|root,COG1076@2|Bacteria,3J1CS@40117|Nitrospirae	40117|Nitrospirae	O	DnaJ molecular chaperone homology domain	hscB	-	-	ko:K04082	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	-
CH3_k127_11144437_14	106370.Francci3_3071	5.437e-06	53.0	COG2104@1|root,COG2104@2|Bacteria	2|Bacteria	H	thiamine diphosphate biosynthetic process	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	iJN678.ycf40	ThiS
CH3_k127_11144437_7	589865.DaAHT2_0949	1.529e-18	89.0	COG0296@1|root,COG0296@2|Bacteria,1NIZI@1224|Proteobacteria,42WYM@68525|delta/epsilon subdivisions,2WSNX@28221|Deltaproteobacteria,2MMER@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Glycogen recognition site of AMP-activated protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM
CH3_k127_11144437_10	941639.BCO26_0693	2.608e-10	68.0	COG5433@1|root,COG5433@2|Bacteria,1V3B8@1239|Firmicutes,4HXV7@91061|Bacilli,1ZRZP@1386|Bacillus	91061|Bacilli	L	PFAM Transposase_11	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
CH3_k127_11144437_6	941639.BCO26_2507	8.648e-35	149.0	COG5433@1|root,COG5433@2|Bacteria,1V3B8@1239|Firmicutes,4HXV7@91061|Bacilli,1ZRZP@1386|Bacillus	91061|Bacilli	L	PFAM Transposase_11	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
CH3_k127_11144437_11	864069.MicloDRAFT_00004920	7.057e-10	66.0	2AGJR@1|root,316ST@2|Bacteria,1NGZF@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_11185057_3	945543.VIBR0546_02675	1.818e-07	61.0	COG3209@1|root,COG3209@2|Bacteria,1PDT2@1224|Proteobacteria,1TEF8@1236|Gammaproteobacteria,1XZDG@135623|Vibrionales	135623|Vibrionales	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_11185057_1	240016.ABIZ01000001_gene5629	4.253e-43	166.0	COG2912@1|root,COG2912@2|Bacteria	2|Bacteria	P	Transglutaminase-like superfamily	CP_0628	-	-	-	-	-	-	-	-	-	-	-	TPR_9,Transglut_core2,VIT
CH3_k127_11185057_0	526218.Sterm_4083	6.626e-103	349.0	COG5505@1|root,COG5505@2|Bacteria,37B8T@32066|Fusobacteria	32066|Fusobacteria	S	Protein of unknown function (DUF819)	-	-	-	-	-	-	-	-	-	-	-	-	DUF819
CH3_k127_11185057_2	443143.GM18_3718	4.616e-43	163.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,42M3E@68525|delta/epsilon subdivisions,2WKMK@28221|Deltaproteobacteria,43TH3@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
CH3_k127_11223134_2	391625.PPSIR1_08312	1.156e-126	421.0	COG5434@1|root,COG5434@2|Bacteria,1RJPM@1224|Proteobacteria,42T21@68525|delta/epsilon subdivisions,2WPCS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
CH3_k127_11223134_4	504728.K649_06595	2.1e-61	225.0	COG3257@1|root,COG3257@2|Bacteria,1WJWA@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	protein possibly involved in glyoxylate utilization	-	-	3.5.3.26	ko:K14977	ko00230,ko01120,map00230,map01120	-	R05554	RC01419	ko00000,ko00001,ko01000	-	-	-	Cupin_2
CH3_k127_11223134_3	765911.Thivi_4549	1.616e-92	312.0	COG1355@1|root,COG1355@2|Bacteria,1MXK5@1224|Proteobacteria,1RQPK@1236|Gammaproteobacteria,1WX63@135613|Chromatiales	135613|Chromatiales	S	Belongs to the MEMO1 family	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
CH3_k127_11223134_1	926569.ANT_29620	8.249e-130	428.0	COG1180@1|root,COG1180@2|Bacteria,2G6B2@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Radical SAM domain protein	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
CH3_k127_11223134_0	452637.Oter_3827	7.803e-135	433.0	COG0057@1|root,COG0057@2|Bacteria,46S59@74201|Verrucomicrobia,3K77U@414999|Opitutae	414999|Opitutae	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	-	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
CH3_k127_11226521_3	338966.Ppro_2630	2.808e-42	160.0	COG0543@1|root,COG0543@2|Bacteria,1RF43@1224|Proteobacteria,42RQK@68525|delta/epsilon subdivisions,2WNJU@28221|Deltaproteobacteria,43U15@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
CH3_k127_11226521_1	264732.Moth_2127	1.988e-103	344.0	COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,248CQ@186801|Clostridia,42FGV@68295|Thermoanaerobacterales	186801|Clostridia	F	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
CH3_k127_11226521_4	1379698.RBG1_1C00001G1401	3.776e-17	91.0	COG1520@1|root,COG1520@2|Bacteria,2NQ51@2323|unclassified Bacteria	2|Bacteria	O	NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,PQQ_2,SBBP
CH3_k127_11226521_0	1123253.AUBD01000004_gene1089	1.093e-209	664.0	COG0538@1|root,COG0538@2|Bacteria,1MW3J@1224|Proteobacteria,1RNMD@1236|Gammaproteobacteria,1X3IR@135614|Xanthomonadales	135614|Xanthomonadales	C	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,Iso_dh
CH3_k127_11226521_2	1173028.ANKO01000194_gene6028	1.899e-96	352.0	COG3250@1|root,COG3250@2|Bacteria,1G4FY@1117|Cyanobacteria,1HA7W@1150|Oscillatoriales	1117|Cyanobacteria	G	Glycosyl hydrolases family 2	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
CH3_k127_11243117_2	1123242.JH636434_gene4299	6.411e-76	272.0	COG2755@1|root,COG2755@2|Bacteria,2IZUG@203682|Planctomycetes	203682|Planctomycetes	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CH3_k127_11243117_9	1118059.CAHC01000003_gene959	2.304e-08	63.0	COG0507@1|root,COG0507@2|Bacteria,1V27I@1239|Firmicutes,24GPP@186801|Clostridia	186801|Clostridia	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_11243117_8	926556.Echvi_3203	1.785e-18	91.0	COG3385@1|root,COG5421@1|root,COG3385@2|Bacteria,COG5421@2|Bacteria,4NXT2@976|Bacteroidetes	976|Bacteroidetes	L	hmm pf01609	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
CH3_k127_11243117_11	497964.CfE428DRAFT_0066	2.095e-06	50.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,46TTW@74201|Verrucomicrobia	74201|Verrucomicrobia	KLT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PEGA,Pkinase
CH3_k127_11243117_3	686340.Metal_3113	7.75e-75	292.0	COG3291@1|root,COG3291@2|Bacteria,1R7A1@1224|Proteobacteria,1S0A9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	IgGFc binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IgGFc_binding
CH3_k127_11243117_4	1430440.MGMSRv2_2439	1.724e-64	258.0	COG1520@1|root,COG1520@2|Bacteria,1QV8R@1224|Proteobacteria	1224|Proteobacteria	G	6-phosphogluconolactonase activity	-	-	-	ko:K20952	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Beta-prism_lec,DUF4347,HYR,VCBS
CH3_k127_11243117_12	867845.KI911784_gene210	1.672e-05	62.0	COG3391@1|root,COG3391@2|Bacteria,2GBRT@200795|Chloroflexi,376BG@32061|Chloroflexia	32061|Chloroflexia	S	PA14	-	-	-	-	-	-	-	-	-	-	-	-	NHL,PA14
CH3_k127_11243117_10	1502851.FG93_00043	1.082e-06	66.0	COG1404@1|root,COG2931@1|root,COG4932@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,COG4932@2|Bacteria,1QYHZ@1224|Proteobacteria,2UHT4@28211|Alphaproteobacteria,3K04W@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	SdrD_B
CH3_k127_11243117_5	856793.MICA_147	1.347e-52	218.0	COG1520@1|root,COG1520@2|Bacteria,1R0E4@1224|Proteobacteria,2UJBQ@28211|Alphaproteobacteria,4BSD7@82117|unclassified Alphaproteobacteria	1224|Proteobacteria	S	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP_2
CH3_k127_11243117_1	99598.Cal7507_3395	2.572e-97	366.0	COG1520@1|root,COG1520@2|Bacteria,1GHEB@1117|Cyanobacteria,1HKIG@1161|Nostocales	1117|Cyanobacteria	C	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	PPC
CH3_k127_11243117_7	1100720.ALKN01000002_gene1847	3.798e-27	134.0	COG2911@1|root,COG2931@1|root,COG2911@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria	1224|Proteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	3.1.4.50	ko:K01127	ko00563,map00563	-	R06623	-	ko00000,ko00001,ko01000	-	-	-	Big_5,Calx-beta,FG-GAP,HemolysinCabind
CH3_k127_11243117_6	203124.Tery_0117	1.511e-31	148.0	COG1404@1|root,COG4412@1|root,COG1404@2|Bacteria,COG4412@2|Bacteria,1G04D@1117|Cyanobacteria,1H779@1150|Oscillatoriales	1117|Cyanobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,HemolysinCabind,Peptidase_S8,SdrD_B
CH3_k127_11243117_0	595460.RRSWK_02125	0.0	1296.0	COG1357@1|root,COG1511@1|root,COG2931@1|root,COG3291@1|root,COG1357@2|Bacteria,COG1511@2|Bacteria,COG2931@2|Bacteria,COG3291@2|Bacteria,2IZ0P@203682|Planctomycetes	203682|Planctomycetes	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,Laminin_G_3
CH3_k127_11274243_0	641524.ADICYQ_4181	1.16e-59	229.0	COG3533@1|root,COG3533@2|Bacteria	2|Bacteria	S	Beta-L-arabinofuranosidase, GH127	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_127
CH3_k127_11274243_1	1123508.JH636448_gene7659	1.97e-15	80.0	COG2730@1|root,COG2730@2|Bacteria,2IZBB@203682|Planctomycetes	203682|Planctomycetes	G	Protein of unknown function (DUF4038)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF4038,DUF5060
CH3_k127_11274243_2	411901.BACCAC_01784	1.602e-10	75.0	COG1653@1|root,COG1653@2|Bacteria,4NG6U@976|Bacteroidetes,2FRMG@200643|Bacteroidia,4AQHJ@815|Bacteroidaceae	976|Bacteroidetes	G	Right handed beta helix region	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Beta_helix,DUF1565
CH3_k127_113223_2	1405.DJ92_3698	5.907e-31	128.0	COG0531@1|root,COG0531@2|Bacteria,1VS5Q@1239|Firmicutes,4HTCE@91061|Bacilli,1ZEPM@1386|Bacillus	91061|Bacilli	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
CH3_k127_113223_0	1303518.CCALI_00782	2.213e-81	287.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,TAT_signal
CH3_k127_113223_1	1121920.AUAU01000017_gene1239	2.087e-38	151.0	COG0281@1|root,COG0281@2|Bacteria,3Y43V@57723|Acidobacteria	57723|Acidobacteria	C	Malic enzyme, NAD binding domain	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
CH3_k127_1133042_6	742725.HMPREF9450_01532	4.486e-23	104.0	COG3420@1|root,COG3420@2|Bacteria,4PMG9@976|Bacteroidetes,2FQGR@200643|Bacteroidia	976|Bacteroidetes	P	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
CH3_k127_1133042_8	864051.BurJ1DRAFT_0942	1.068e-13	82.0	COG1520@1|root,COG1520@2|Bacteria,1P0W9@1224|Proteobacteria	1224|Proteobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_1133042_9	1303518.CCALI_01450	3.888e-11	74.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
CH3_k127_1133042_4	1165841.SULAR_01175	6.669e-42	162.0	COG0400@1|root,COG0400@2|Bacteria,1RA02@1224|Proteobacteria,42TZV@68525|delta/epsilon subdivisions,2YR1J@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Phospholipase/Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2
CH3_k127_1133042_5	269798.CHU_0700	9.921e-35	138.0	COG2010@1|root,COG2010@2|Bacteria,4NQN1@976|Bacteroidetes,47XSN@768503|Cytophagia	976|Bacteroidetes	C	Haem-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Haem_bd
CH3_k127_1133042_3	240016.ABIZ01000001_gene3616	1.769e-59	214.0	COG1595@1|root,COG1595@2|Bacteria,46SWN@74201|Verrucomicrobia,2IUE1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CH3_k127_1133042_1	497964.CfE428DRAFT_2060	7.402e-75	263.0	COG0142@1|root,COG0142@2|Bacteria,46SKW@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
CH3_k127_1133042_0	118166.JH976538_gene5057	2.475e-92	327.0	COG4191@1|root,COG4191@2|Bacteria,1G1PE@1117|Cyanobacteria,1H8US@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_8,Response_reg
CH3_k127_1133042_7	886293.Sinac_0920	4.106e-14	78.0	COG0673@1|root,COG0673@2|Bacteria,2IWZW@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CH3_k127_1133042_2	452637.Oter_0712	8.226e-63	237.0	COG1714@1|root,COG1714@2|Bacteria	2|Bacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
CH3_k127_11339759_2	452637.Oter_1936	1.939e-15	79.0	COG0582@1|root,COG0582@2|Bacteria,46TD6@74201|Verrucomicrobia,3K9G2@414999|Opitutae	414999|Opitutae	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
CH3_k127_11339759_0	1321778.HMPREF1982_00675	8.465e-111	372.0	COG1455@1|root,COG1455@2|Bacteria,1TP8D@1239|Firmicutes,24808@186801|Clostridia,26AG8@186813|unclassified Clostridiales	186801|Clostridia	G	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane	-	-	-	ko:K02761	ko00500,ko02060,map00500,map02060	M00275	R11170,R11172	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.3.2	-	-	PTS_EIIC
CH3_k127_11339759_5	297246.lpp1558	1.981e-08	60.0	COG2801@1|root,COG2801@2|Bacteria,1MWVQ@1224|Proteobacteria,1RN12@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_29,rve
CH3_k127_11339759_1	1121289.JHVL01000023_gene71	6.901e-45	174.0	COG1211@1|root,COG1211@2|Bacteria,1V3M7@1239|Firmicutes,248E6@186801|Clostridia,36EIP@31979|Clostridiaceae	186801|Clostridia	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS20335	IspD
CH3_k127_11339759_3	1303518.CCALI_00933	3.683e-15	88.0	COG4537@1|root,COG4537@2|Bacteria	2|Bacteria	U	Required for transformation and DNA binding	comGC	GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944	-	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	M00331,M00429	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
CH3_k127_11339759_4	661478.OP10G_2992	1.563e-11	74.0	COG4537@1|root,COG4537@2|Bacteria	2|Bacteria	U	Required for transformation and DNA binding	comGC	GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944	-	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	M00331,M00429	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
CH3_k127_11340204_5	761193.Runsl_5537	4.281e-110	365.0	COG2382@1|root,COG3386@1|root,COG2382@2|Bacteria,COG3386@2|Bacteria,4NK15@976|Bacteroidetes,47MMH@768503|Cytophagia	976|Bacteroidetes	P	Putative esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase,SGL
CH3_k127_11340204_9	530564.Psta_0575	1.278e-37	146.0	COG0662@1|root,COG0662@2|Bacteria,2J4Q9@203682|Planctomycetes	203682|Planctomycetes	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CH3_k127_11340204_8	321332.CYB_1025	2.166e-39	149.0	COG0607@1|root,COG0607@2|Bacteria,1GPXG@1117|Cyanobacteria,1H0XW@1129|Synechococcus	1117|Cyanobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CH3_k127_11340204_3	756499.Desde_1902	2.69e-165	536.0	COG0075@1|root,COG3916@1|root,COG0075@2|Bacteria,COG3916@2|Bacteria,1TPS0@1239|Firmicutes,24919@186801|Clostridia	186801|Clostridia	E	Aminotransferase	-	-	2.6.1.37	ko:K03430	ko00440,ko01100,ko01120,map00440,map01100,map01120	-	R04152	RC00008,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_5
CH3_k127_11340204_7	443143.GM18_1309	5.207e-40	156.0	COG0344@1|root,COG0344@2|Bacteria	2|Bacteria	I	acyl-phosphate glycerol-3-phosphate acyltransferase activity	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
CH3_k127_11340204_1	56780.SYN_00905	1.7e-171	556.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,42ME5@68525|delta/epsilon subdivisions,2WKA2@28221|Deltaproteobacteria,2MQBJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
CH3_k127_11340204_4	344747.PM8797T_00347	3.063e-123	407.0	COG1158@1|root,COG1158@2|Bacteria,2IXBX@203682|Planctomycetes	203682|Planctomycetes	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	-	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_RNA_bind
CH3_k127_11340204_2	240016.ABIZ01000001_gene2661	1.831e-171	543.0	COG0031@1|root,COG0031@2|Bacteria,46W12@74201|Verrucomicrobia,2IWMW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CH3_k127_11340204_6	1121441.AUCX01000016_gene2382	1.256e-42	180.0	COG2199@1|root,COG2208@1|root,COG2208@2|Bacteria,COG3706@2|Bacteria,1N4K5@1224|Proteobacteria,42RTP@68525|delta/epsilon subdivisions,2WN9M@28221|Deltaproteobacteria,2M9XH@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	PAS_8,Response_reg,SpoIIE
CH3_k127_11340204_0	118168.MC7420_4981	9.582e-187	613.0	COG0642@1|root,COG2202@1|root,COG4251@1|root,COG0642@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG4251@2|Bacteria,1G09B@1117|Cyanobacteria,1H82F@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,GAF,GAF_3,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
CH3_k127_1134811_8	1192034.CAP_1634	2.081e-08	63.0	COG3829@1|root,COG3829@2|Bacteria	2|Bacteria	T	transcription factor binding	-	-	-	-	-	-	-	-	-	-	-	-	FHA,HTH_8,Sigma54_activat,Yop-YscD_cpl
CH3_k127_1134811_7	452637.Oter_3848	2.995e-14	76.0	2EPKD@1|root,33H70@2|Bacteria,46WC0@74201|Verrucomicrobia,3K89T@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_1134811_1	886293.Sinac_0152	6.9e-101	334.0	COG4221@1|root,COG4221@2|Bacteria,2IXHG@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CH3_k127_1134811_5	1123371.ATXH01000009_gene1101	6.226e-69	242.0	COG1912@1|root,COG1912@2|Bacteria,2GHAQ@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
CH3_k127_1134811_6	237368.SCABRO_03960	4.605e-67	236.0	COG0705@1|root,COG0705@2|Bacteria,2IZZY@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
CH3_k127_1134811_2	452637.Oter_1130	6.233e-99	334.0	COG0484@1|root,COG0484@2|Bacteria,46S6P@74201|Verrucomicrobia,3K8ZD@414999|Opitutae	414999|Opitutae	O	DnaJ molecular chaperone homology domain	-	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
CH3_k127_1134811_0	518766.Rmar_2586	6.37e-129	422.0	COG0479@1|root,COG0479@2|Bacteria	2|Bacteria	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	asrA	-	-	ko:K16950	ko00920,ko01120,map00920,map01120	-	R00858,R10146	RC00065	ko00000,ko00001	-	-	-	Fer4_22
CH3_k127_1134811_4	136993.KB900626_gene2135	2.299e-94	317.0	COG0543@1|root,COG0543@2|Bacteria,1R6QZ@1224|Proteobacteria,2V487@28211|Alphaproteobacteria,36ZQF@31993|Methylocystaceae	28211|Alphaproteobacteria	CH	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B	-	-	-	-	-	-	-	-	-	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
CH3_k127_1134811_3	518766.Rmar_2589	9.605e-99	334.0	COG1941@1|root,COG1941@2|Bacteria	2|Bacteria	C	coenzyme F420 hydrogenase activity	hoxY	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q6
CH3_k127_11348459_0	926560.KE387023_gene1701	1.083e-195	638.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,DUF3365,GAF,GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
CH3_k127_11348459_3	1219084.AP014508_gene1338	2.151e-13	82.0	COG0745@1|root,COG0745@2|Bacteria,2GDAM@200918|Thermotogae	200918|Thermotogae	T	PFAM response regulator receiver	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
CH3_k127_11348459_2	497964.CfE428DRAFT_5353	1.026e-35	151.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,HATPase_c,HD_5,Response_reg,T2SSE_N
CH3_k127_11348459_1	224325.AF_2211	9.474e-51	187.0	COG0537@1|root,arCOG00419@2157|Archaea,2XWGT@28890|Euryarchaeota,2466N@183980|Archaeoglobi	183980|Archaeoglobi	F	HIT domain	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
CH3_k127_11365030_3	243090.RB12844	1.621e-112	372.0	COG3622@1|root,COG3622@2|Bacteria,2J4Z5@203682|Planctomycetes	203682|Planctomycetes	G	PFAM Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CH3_k127_11365030_2	497964.CfE428DRAFT_3487	1.397e-115	407.0	COG4191@1|root,COG4191@2|Bacteria,46TV0@74201|Verrucomicrobia	74201|Verrucomicrobia	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,Response_reg
CH3_k127_11365030_10	1173026.Glo7428_2699	1.393e-52	193.0	COG0784@1|root,COG0784@2|Bacteria,1G548@1117|Cyanobacteria	1117|Cyanobacteria	T	PFAM Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CH3_k127_11365030_6	306281.AJLK01000140_gene1050	1.955e-86	308.0	COG2199@1|root,COG2202@1|root,COG2203@1|root,COG4251@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3706@2|Bacteria,COG4251@2|Bacteria,1G1Z5@1117|Cyanobacteria,1JHUP@1189|Stigonemataceae	1117|Cyanobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_3,Response_reg
CH3_k127_11365030_8	497964.CfE428DRAFT_0879	1.741e-78	277.0	COG3494@1|root,COG3494@2|Bacteria,46SJ6@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF1009)	-	-	-	ko:K09949	-	-	-	-	ko00000	-	-	-	DUF1009
CH3_k127_11365030_1	1396418.BATQ01000099_gene5573	1.461e-175	561.0	COG3119@1|root,COG3119@2|Bacteria,46XAA@74201|Verrucomicrobia,2IV6B@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CH3_k127_11365030_0	452637.Oter_2055	9.035e-209	656.0	COG4656@1|root,COG4656@2|Bacteria,46W83@74201|Verrucomicrobia	74201|Verrucomicrobia	C	RnfC Barrel sandwich hybrid domain	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_51K,Fer4_17,RnfC_N,SLBB
CH3_k127_11365030_9	452637.Oter_2056	7.827e-78	264.0	COG4577@1|root,COG4577@2|Bacteria	2|Bacteria	CQ	ethanolamine catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	BMC
CH3_k127_11365030_7	28444.JODQ01000005_gene1401	3.552e-85	291.0	COG1572@1|root,COG2133@1|root,COG2374@1|root,COG3291@1|root,COG3828@1|root,COG1572@2|Bacteria,COG2133@2|Bacteria,COG2374@2|Bacteria,COG3291@2|Bacteria,COG3828@2|Bacteria,2GJFY@201174|Actinobacteria,4EKGY@85012|Streptosporangiales	201174|Actinobacteria	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	ASH,CBM_6,DUF1349,F5_F8_type_C,GSDH,PKD,Ricin_B_lectin,ThuA
CH3_k127_11365030_4	102125.Xen7305DRAFT_00043350	5.987e-112	384.0	COG0591@1|root,COG0591@2|Bacteria,1G1JV@1117|Cyanobacteria,3VHP2@52604|Pleurocapsales	1117|Cyanobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
CH3_k127_11365030_5	886293.Sinac_6489	3.264e-107	360.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
CH3_k127_11404597_2	497964.CfE428DRAFT_3502	2.948e-49	189.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,46THN@74201|Verrucomicrobia	74201|Verrucomicrobia	CG	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
CH3_k127_11404597_0	344747.PM8797T_08389	1.284e-210	668.0	COG1520@1|root,COG1520@2|Bacteria,2IWVH@203682|Planctomycetes	203682|Planctomycetes	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_11404597_4	1121091.AUMP01000008_gene3528	3.613e-05	50.0	COG3209@1|root,COG3209@2|Bacteria,1TR8F@1239|Firmicutes,4HBZE@91061|Bacilli	91061|Bacilli	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	PT-TG,RHS_repeat
CH3_k127_11404597_1	1123242.JH636434_gene4354	3.867e-186	595.0	COG4102@1|root,COG4102@2|Bacteria,2IX5T@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CH3_k127_11404597_3	1123508.JH636452_gene7001	2.34e-06	50.0	COG2010@1|root,COG2010@2|Bacteria,2IXJ6@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
CH3_k127_11408755_5	344747.PM8797T_21498	2.069e-104	359.0	COG0515@1|root,COG0515@2|Bacteria,2IXG3@203682|Planctomycetes	203682|Planctomycetes	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	HDOD,Pkinase,dCache_1
CH3_k127_11408755_6	485913.Krac_10089	4.186e-80	274.0	COG2326@1|root,COG2326@2|Bacteria,2G5UP@200795|Chloroflexi	200795|Chloroflexi	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
CH3_k127_11408755_7	546266.NEIMUCOT_06302	5.606e-68	244.0	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,2VPGP@28216|Betaproteobacteria,2KQN6@206351|Neisseriales	206351|Neisseriales	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
CH3_k127_11408755_3	1396141.BATP01000020_gene50	3.2e-212	702.0	COG5337@1|root,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
CH3_k127_11408755_4	243231.GSU3381	1.827e-182	607.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,42MAH@68525|delta/epsilon subdivisions,2WJT7@28221|Deltaproteobacteria,43TFF@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
CH3_k127_11408755_2	1123070.KB899248_gene60	4.359e-215	676.0	COG0017@1|root,COG0017@2|Bacteria,46TN6@74201|Verrucomicrobia,2ITHF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	tRNA synthetases class II (D, K and N)	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
CH3_k127_11408755_0	497964.CfE428DRAFT_3579	4.079e-235	752.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
CH3_k127_11408755_1	497964.CfE428DRAFT_3580	9.527e-235	734.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CH3_k127_11436664_4	349741.Amuc_1584	8.934e-114	381.0	COG1459@1|root,COG1459@2|Bacteria,46U60@74201|Verrucomicrobia,2IWMJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	NU	Type II secretion system (T2SS), protein F	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
CH3_k127_11436664_12	452637.Oter_0312	2.114e-06	63.0	COG3291@1|root,COG3386@1|root,COG3291@2|Bacteria,COG3386@2|Bacteria,46ZJT@74201|Verrucomicrobia	2|Bacteria	G	Immunoglobulin I-set domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,He_PIG,PKD
CH3_k127_11436664_9	641524.ADICYQ_5597	1.123e-18	104.0	COG5337@1|root,COG5337@2|Bacteria,4NEH2@976|Bacteroidetes,47PGS@768503|Cytophagia	976|Bacteroidetes	M	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Fn3_assoc,LTD
CH3_k127_11436664_2	1396141.BATP01000020_gene108	4.546e-124	452.0	COG2312@1|root,COG4870@1|root,COG2312@2|Bacteria,COG4870@2|Bacteria,46XD5@74201|Verrucomicrobia,2IVHX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Fn3_assoc,LTD
CH3_k127_11436664_10	324602.Caur_0211	1.855e-15	93.0	COG1319@1|root,COG3391@1|root,COG1319@2|Bacteria,COG3391@2|Bacteria,2GA7F@200795|Chloroflexi,376QS@32061|Chloroflexia	32061|Chloroflexia	C	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_11436664_6	497964.CfE428DRAFT_2594	1.265e-61	222.0	COG2138@1|root,COG2138@2|Bacteria,46SPE@74201|Verrucomicrobia	74201|Verrucomicrobia	S	CbiX	-	-	4.99.1.3	ko:K03795	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05807	RC01012	ko00000,ko00001,ko01000	-	-	-	CbiX
CH3_k127_11436664_8	234267.Acid_7405	1.924e-61	222.0	COG2084@1|root,COG2084@2|Bacteria	2|Bacteria	I	phosphogluconate dehydrogenase (decarboxylating) activity	mmsB	-	1.1.1.31,1.1.1.60	ko:K00020,ko:K00042	ko00280,ko00630,ko01100,map00280,map00630,map01100	-	R01745,R01747,R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
CH3_k127_11436664_11	344747.PM8797T_17187	6.99e-07	62.0	COG1621@1|root,COG1621@2|Bacteria,2IY26@203682|Planctomycetes	203682|Planctomycetes	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_11436664_7	1123508.JH636450_gene7204	1.316e-61	233.0	COG0673@1|root,COG0673@2|Bacteria,2IXVF@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CH3_k127_11436664_5	326297.Sama_0297	1.491e-113	379.0	COG3828@1|root,COG3828@2|Bacteria,1QVR0@1224|Proteobacteria,1SN58@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Glycosyl hydrolase family 99	-	-	3.2.1.130	ko:K15538	-	-	-	-	ko00000,ko01000	-	GH99	-	Glyco_hydro_99
CH3_k127_11436664_1	595460.RRSWK_00087	1.467e-172	565.0	COG1874@1|root,COG1874@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	3.2.1.23	ko:K01190,ko:K12308	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Cellulase,Glyco_hydro_42,Glyco_hydro_42M
CH3_k127_11436664_3	509635.N824_15295	8.925e-123	420.0	2DBGI@1|root,2Z94U@2|Bacteria,4NI4P@976|Bacteroidetes,1IVFE@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_11436664_0	1121405.dsmv_0691	5.687e-192	615.0	COG5421@1|root,COG5421@2|Bacteria,1R3NX@1224|Proteobacteria,42QDV@68525|delta/epsilon subdivisions,2WIRQ@28221|Deltaproteobacteria,2MN1S@213118|Desulfobacterales	68525|delta/epsilon subdivisions	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
CH3_k127_11474445_6	887929.HMP0721_1566	7.175e-24	101.0	COG0080@1|root,COG0080@2|Bacteria,1V1BS@1239|Firmicutes,24FSQ@186801|Clostridia,25WDI@186806|Eubacteriaceae	186801|Clostridia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
CH3_k127_11474445_5	278957.ABEA03000094_gene4759	1.287e-58	210.0	COG0250@1|root,COG0250@2|Bacteria,46SR6@74201|Verrucomicrobia,3K7UE@414999|Opitutae	414999|Opitutae	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
CH3_k127_11474445_8	59374.Fisuc_1277	7.689e-06	53.0	COG0690@1|root,COG0690@2|Bacteria	2|Bacteria	U	P-P-bond-hydrolysis-driven protein transmembrane transporter activity	secE	GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
CH3_k127_11474445_1	452637.Oter_0239	9.917e-195	614.0	COG0050@1|root,COG0050@2|Bacteria,46SFG@74201|Verrucomicrobia,3K7E9@414999|Opitutae	414999|Opitutae	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
CH3_k127_11474445_3	497964.CfE428DRAFT_4766	6.656e-88	303.0	COG1039@1|root,COG1039@2|Bacteria,46UTB@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	-	-	3.1.26.4	ko:K03471	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
CH3_k127_11474445_4	197221.22294801	2.965e-73	263.0	COG1051@1|root,COG1194@1|root,COG1051@2|Bacteria,COG1194@2|Bacteria,1G7MC@1117|Cyanobacteria	1117|Cyanobacteria	L	A G-specific adenine glycosylase	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
CH3_k127_11474445_2	497964.CfE428DRAFT_6359	4.632e-121	401.0	COG1104@1|root,COG1104@2|Bacteria,46SFF@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Aminotransferase class-V	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
CH3_k127_11474445_0	344747.PM8797T_24941	1.462e-216	682.0	COG3119@1|root,COG3119@2|Bacteria,2IX9T@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CH3_k127_11479103_7	1397528.Q671_06095	5.85e-14	72.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,1RQP7@1236|Gammaproteobacteria,1XR29@135619|Oceanospirillales	135619|Oceanospirillales	L	DNA polymerase	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
CH3_k127_11479103_2	497964.CfE428DRAFT_6265	4.623e-53	190.0	COG3344@1|root,COG3344@2|Bacteria	2|Bacteria	L	reverse transcriptase	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,RVT_1
CH3_k127_11479103_3	1242864.D187_010252	1.033e-51	188.0	COG0476@1|root,COG0476@2|Bacteria,1Q38H@1224|Proteobacteria,438ZG@68525|delta/epsilon subdivisions,2X44R@28221|Deltaproteobacteria,2YY93@29|Myxococcales	28221|Deltaproteobacteria	H	ThiF family	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
CH3_k127_11479103_5	671143.DAMO_2920	3.579e-27	118.0	2DRSH@1|root,33CVS@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_11479103_6	1196083.SALWKB12_1701	7.373e-15	85.0	COG3012@1|root,COG3012@2|Bacteria,1NGS9@1224|Proteobacteria	1224|Proteobacteria	S	SEC-C motif	-	-	-	-	-	-	-	-	-	-	-	-	SEC-C
CH3_k127_11479103_1	497964.CfE428DRAFT_3809	3.495e-61	222.0	COG0330@1|root,COG0330@2|Bacteria,46VZD@74201|Verrucomicrobia	74201|Verrucomicrobia	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
CH3_k127_11479103_8	697282.Mettu_1883	7.716e-06	56.0	2DEM1@1|root,2ZNEB@2|Bacteria,1P8KJ@1224|Proteobacteria,1SVJ0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_11479103_4	316274.Haur_0034	1.439e-41	161.0	COG2968@1|root,COG2968@2|Bacteria	2|Bacteria	S	cellular response to heat	-	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
CH3_k127_11479103_0	509191.AEDB02000002_gene1137	1.309e-118	413.0	COG0823@1|root,COG0823@2|Bacteria,1VP24@1239|Firmicutes,24WTQ@186801|Clostridia,3WN5Z@541000|Ruminococcaceae	186801|Clostridia	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
CH3_k127_11498525_0	765914.ThisiDRAFT_1796	2.301e-46	175.0	COG0500@1|root,COG2226@2|Bacteria,1N9JV@1224|Proteobacteria,1RP9E@1236|Gammaproteobacteria,1WZRJ@135613|Chromatiales	135613|Chromatiales	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CH3_k127_11498525_2	530564.Psta_1650	7.162e-15	78.0	COG1520@1|root,COG1520@2|Bacteria,2IXXG@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
CH3_k127_11498525_1	1189612.A33Q_2397	1.112e-39	153.0	COG5485@1|root,COG5485@2|Bacteria,4NXNY@976|Bacteroidetes,47X7G@768503|Cytophagia	976|Bacteroidetes	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
CH3_k127_11498525_3	1107311.Q767_03870	1.467e-09	65.0	2CI9Y@1|root,33QR4@2|Bacteria,4NZX3@976|Bacteroidetes,1I77D@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_11520812_3	1157708.KB907454_gene2941	3.193e-10	71.0	COG4447@1|root,COG4886@1|root,COG4447@2|Bacteria,COG4886@2|Bacteria,1PIDF@1224|Proteobacteria,2WBU7@28216|Betaproteobacteria,4AIC2@80864|Comamonadaceae	28216|Betaproteobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_11520812_2	324602.Caur_0299	4.786e-16	89.0	COG5295@1|root,COG5295@2|Bacteria,2GB82@200795|Chloroflexi,377IZ@32061|Chloroflexia	32061|Chloroflexia	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectinesterase
CH3_k127_11520812_4	1121116.KB894765_gene643	0.000426	53.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,2VJCZ@28216|Betaproteobacteria,4AAY1@80864|Comamonadaceae	28216|Betaproteobacteria	O	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	ppiD	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
CH3_k127_11520812_0	497964.CfE428DRAFT_0845	1.06e-119	391.0	COG0078@1|root,COG0078@2|Bacteria,46SA5@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
CH3_k127_11520812_1	478741.JAFS01000002_gene596	2.703e-45	171.0	COG4992@1|root,COG4992@2|Bacteria,46SUV@74201|Verrucomicrobia,37G7B@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	E	Aminotransferase class-III	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CH3_k127_11523926_0	237368.SCABRO_02223	8.957e-135	434.0	COG0714@1|root,COG0714@2|Bacteria,2IX23@203682|Planctomycetes	203682|Planctomycetes	S	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CH3_k127_11523926_8	237368.SCABRO_02173	1.065e-07	54.0	COG3668@1|root,COG3668@2|Bacteria	2|Bacteria	D	Plasmid stabilization system	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
CH3_k127_11523926_7	883080.HMPREF9697_02951	9.246e-08	55.0	COG3668@1|root,COG3668@2|Bacteria,1N569@1224|Proteobacteria	1224|Proteobacteria	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
CH3_k127_11523926_10	1137269.AZWL01000006_gene6788	3.922e-06	57.0	COG0666@1|root,COG0666@2|Bacteria,2IIAC@201174|Actinobacteria	201174|Actinobacteria	T	Ankyrin repeat	-	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank_2,Ank_4,Ank_5
CH3_k127_11523926_6	317655.Sala_2653	3.167e-08	64.0	2BZB1@1|root,32R4P@2|Bacteria,1RH72@1224|Proteobacteria,2UB2J@28211|Alphaproteobacteria,2KA29@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_11523926_3	237368.SCABRO_01880	2.024e-97	332.0	COG1721@1|root,COG1721@2|Bacteria,2IXT7@203682|Planctomycetes	203682|Planctomycetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CH3_k127_11523926_5	237368.SCABRO_01881	8.316e-23	107.0	2DQN8@1|root,337RD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_11523926_2	497964.CfE428DRAFT_3459	1.158e-97	330.0	COG2304@1|root,COG2304@2|Bacteria,46TTR@74201|Verrucomicrobia	74201|Verrucomicrobia	S	von Willebrand factor type A domain	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA
CH3_k127_11523926_1	1167006.UWK_00742	3.123e-107	368.0	COG0457@1|root,COG2304@1|root,COG5414@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,COG5414@2|Bacteria,1MW51@1224|Proteobacteria,42M45@68525|delta/epsilon subdivisions,2WM19@28221|Deltaproteobacteria,2MHT6@213118|Desulfobacterales	28221|Deltaproteobacteria	K	PFAM von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	TPR_1,TPR_16,TPR_2,VWA,VWA_2
CH3_k127_11523926_9	880073.Calab_2477	4.448e-07	58.0	2E5Q4@1|root,330ER@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_11523926_4	452637.Oter_2332	1.023e-35	144.0	COG0359@1|root,COG0359@2|Bacteria,46SYE@74201|Verrucomicrobia,3K82A@414999|Opitutae	414999|Opitutae	J	Binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
CH3_k127_11526192_2	330214.NIDE3030	6.645e-57	212.0	COG0859@1|root,COG0859@2|Bacteria,3J0KI@40117|Nitrospirae	40117|Nitrospirae	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02841,ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
CH3_k127_11526192_1	497964.CfE428DRAFT_1198	2.573e-101	334.0	COG0639@1|root,COG0639@2|Bacteria,46TA5@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Calcineurin-like phosphoesterase superfamily domain	apaH	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
CH3_k127_11526192_3	240016.ABIZ01000001_gene2409	7.545e-17	85.0	COG1254@1|root,COG1254@2|Bacteria,46W9W@74201|Verrucomicrobia,2IUZQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Acylphosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Acylphosphatase
CH3_k127_11526192_0	497964.CfE428DRAFT_5154	8.839e-123	422.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,46U3B@74201|Verrucomicrobia	2|Bacteria	S	Putative glutamine amidotransferase	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,GATase1_like,VWA,VWA_2,VWA_3
CH3_k127_11545067_1	240016.ABIZ01000001_gene1545	2.366e-45	170.0	COG0346@1|root,COG0346@2|Bacteria,46SUF@74201|Verrucomicrobia,2IUKG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CH3_k127_11545067_2	278957.ABEA03000062_gene3554	4.681e-13	79.0	COG2165@1|root,COG2165@2|Bacteria,46YIN@74201|Verrucomicrobia,3K9NX@414999|Opitutae	414999|Opitutae	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
CH3_k127_11545067_3	1210884.HG799465_gene12051	1.208e-08	66.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CH3_k127_11545067_0	452637.Oter_1547	0.0	1244.0	COG3808@1|root,COG3808@2|Bacteria,46S7R@74201|Verrucomicrobia,3K82Q@414999|Opitutae	414999|Opitutae	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
CH3_k127_11546036_11	1283299.AUKG01000003_gene290	1.116e-05	57.0	COG1524@1|root,COG2936@1|root,COG1524@2|Bacteria,COG2936@2|Bacteria,2GJ2K@201174|Actinobacteria	201174|Actinobacteria	E	dipeptidyl-peptidase	-	-	3.4.14.11	ko:K01281	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PepX_C,Peptidase_S15
CH3_k127_11546036_8	1449357.JQLK01000001_gene1667	1.145e-35	149.0	2A1UA@1|root,30Q39@2|Bacteria,1WM6W@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_11546036_10	1123242.JH636435_gene2068	1.268e-07	64.0	COG1413@1|root,COG1413@2|Bacteria,2J011@203682|Planctomycetes	203682|Planctomycetes	C	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
CH3_k127_11546036_9	661478.OP10G_4802	2.433e-17	91.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02650,ko:K02679	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10
CH3_k127_11546036_7	1122915.AUGY01000087_gene5226	8.285e-56	212.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,4H9ZM@91061|Bacilli,26S70@186822|Paenibacillaceae	91061|Bacilli	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	2.4.2.8,6.3.4.19	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R01132,R01229,R02142,R09597	RC00063,RC00122,RC02633,RC02634	ko00000,ko00001,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
CH3_k127_11546036_6	1396141.BATP01000032_gene4347	2.646e-66	235.0	COG0386@1|root,COG0386@2|Bacteria,46V2M@74201|Verrucomicrobia,2IUDT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Glutathione peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	GSHPx
CH3_k127_11546036_0	1396141.BATP01000040_gene2102	4.669e-127	423.0	COG4102@1|root,COG4102@2|Bacteria,46T50@74201|Verrucomicrobia,2IUKB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CH3_k127_11546036_3	1396141.BATP01000040_gene2101	7.946e-103	352.0	COG5267@1|root,COG5267@2|Bacteria,46SWV@74201|Verrucomicrobia,2IVM0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
CH3_k127_11546036_1	684949.ATTJ01000001_gene2613	2.464e-114	383.0	COG3842@1|root,COG3842@2|Bacteria,1WIWM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
CH3_k127_11546036_4	321327.CYA_1858	1.491e-87	298.0	COG1176@1|root,COG1176@2|Bacteria,1G127@1117|Cyanobacteria,1H1QV@1129|Synechococcus	1117|Cyanobacteria	P	ABC transporter, permease protein	potB	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
CH3_k127_11546036_5	321332.CYB_2209	8.756e-86	295.0	COG1177@1|root,COG1177@2|Bacteria,1G1B6@1117|Cyanobacteria,1H1XK@1129|Synechococcus	1117|Cyanobacteria	P	ABC transporter, permease protein	potC	-	-	ko:K02053,ko:K11070	ko02010,ko02024,map02010,map02024	M00193,M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11,3.A.1.11.1	-	-	BPD_transp_1
CH3_k127_11546036_2	1122223.KB890700_gene1996	1.003e-113	377.0	COG0687@1|root,COG0687@2|Bacteria,1WIRI@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Spermidine putrescine-binding periplasmic protein	-	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_8
CH3_k127_11549719_0	497964.CfE428DRAFT_3359	3.892e-245	771.0	COG0539@1|root,COG0539@2|Bacteria,46SFY@74201|Verrucomicrobia	74201|Verrucomicrobia	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
CH3_k127_11549719_1	497964.CfE428DRAFT_0727	7.13e-236	739.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,46UC6@74201|Verrucomicrobia	74201|Verrucomicrobia	C	IMP dehydrogenase GMP reductase	-	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
CH3_k127_11575661_7	1499967.BAYZ01000141_gene6156	2.884e-20	92.0	COG4634@1|root,COG4634@2|Bacteria,2NRUB@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Mut7-C
CH3_k127_11575661_8	272123.Anacy_4446	3.153e-20	93.0	COG2442@1|root,COG2442@2|Bacteria,1G7T6@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
CH3_k127_11575661_9	1303518.CCALI_00532	4.572e-20	99.0	COG0476@1|root,COG0607@1|root,COG1977@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,COG1977@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	moeB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006732,GO:0006777,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0018130,GO:0019344,GO:0019538,GO:0019637,GO:0019720,GO:0019752,GO:0020012,GO:0030312,GO:0030682,GO:0042783,GO:0043170,GO:0043207,GO:0043436,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0061605,GO:0070566,GO:0071704,GO:0071944,GO:0075136,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.7.73,2.7.7.80,2.8.1.11	ko:K03148,ko:K03636,ko:K21029,ko:K21147	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF,ThiS
CH3_k127_11575661_11	278963.ATWD01000001_gene2663	0.0002416	44.0	COG2405@1|root,COG2405@2|Bacteria,3Y95W@57723|Acidobacteria,2JNS5@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3368
CH3_k127_11575661_12	395961.Cyan7425_2060	0.0002688	44.0	COG2405@1|root,COG2405@2|Bacteria,1G6NZ@1117|Cyanobacteria,3KKNI@43988|Cyanothece	1117|Cyanobacteria	S	Domain of unknown function (DUF3368)	-	-	-	ko:K07066	-	-	-	-	ko00000	-	-	-	DUF3368
CH3_k127_11575661_10	69014.TK0917	4.552e-11	66.0	COG2886@1|root,arCOG00722@2157|Archaea,2Y0J3@28890|Euryarchaeota,244GE@183968|Thermococci	183968|Thermococci	S	Uncharacterised protein family (UPF0175)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0175
CH3_k127_11575661_3	595460.RRSWK_05050	9.187e-92	312.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
CH3_k127_11575661_2	521674.Plim_1879	1.957e-113	385.0	COG3119@1|root,COG3119@2|Bacteria,2IX9T@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CH3_k127_11575661_4	1304872.JAGC01000003_gene2354	5.749e-67	248.0	COG1520@1|root,COG1520@2|Bacteria,1NYGT@1224|Proteobacteria,42TY0@68525|delta/epsilon subdivisions,2WQ74@28221|Deltaproteobacteria,2M9SS@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotran_2,Arylsulfotrans
CH3_k127_11575661_1	1249627.D779_1354	1.659e-122	409.0	COG1262@1|root,COG1262@2|Bacteria,1R6GS@1224|Proteobacteria,1S5ET@1236|Gammaproteobacteria,1WYQP@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF1566)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566
CH3_k127_11575661_0	1304872.JAGC01000003_gene2354	1.312e-127	427.0	COG1520@1|root,COG1520@2|Bacteria,1NYGT@1224|Proteobacteria,42TY0@68525|delta/epsilon subdivisions,2WQ74@28221|Deltaproteobacteria,2M9SS@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotran_2,Arylsulfotrans
CH3_k127_11575661_5	1394178.AWOO02000018_gene6642	2.525e-36	154.0	COG1262@1|root,COG1262@2|Bacteria,2GK9Q@201174|Actinobacteria,4EH55@85012|Streptosporangiales	201174|Actinobacteria	S	Sulfatase-modifying factor enzyme 1	-	GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005509,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016667,GO:0016670,GO:0018158,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0120147,GO:1901564,GO:1903135,GO:1903136	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
CH3_k127_11575661_6	998674.ATTE01000001_gene970	6.182e-24	105.0	COG1881@1|root,COG1881@2|Bacteria,1NQK5@1224|Proteobacteria,1S0T6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	YHYH protein	-	-	-	-	-	-	-	-	-	-	-	-	PBP,YHYH
CH3_k127_1159950_3	1479239.JQMU01000001_gene2738	8.74e-51	185.0	COG4653@1|root,COG4653@2|Bacteria,1MWMB@1224|Proteobacteria,2TUJN@28211|Alphaproteobacteria,2K6TT@204457|Sphingomonadales	204457|Sphingomonadales	S	Phage capsid family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_capsid
CH3_k127_1159950_0	547045.NEISICOT_01398	4.056e-96	334.0	COG5511@1|root,COG5511@2|Bacteria,1MVN4@1224|Proteobacteria,2VKKT@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Phage portal protein, lambda family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_portal_2
CH3_k127_1159950_6	1144307.PMI04_03648	2.88e-05	53.0	2E13U@1|root,32WJ6@2|Bacteria,1NFFY@1224|Proteobacteria,2UJPN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_1159950_1	278963.ATWD01000001_gene4458	1.024e-91	327.0	COG5525@1|root,COG5525@2|Bacteria,3Y413@57723|Acidobacteria,2JIVD@204432|Acidobacteriia	204432|Acidobacteriia	S	Phage terminase large subunit (GpA)	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_GpA
CH3_k127_1159950_2	794903.OPIT5_06125	1.597e-61	218.0	COG4725@1|root,COG4725@2|Bacteria	2|Bacteria	KT	Belongs to the MT-A70-like family	-	-	-	-	-	-	-	-	-	-	-	-	MT-A70,ParBc
CH3_k127_1159950_4	765911.Thivi_3526	2.311e-21	94.0	COG0863@1|root,COG0863@2|Bacteria,1R1SY@1224|Proteobacteria,1T59K@1236|Gammaproteobacteria,1X22Z@135613|Chromatiales	135613|Chromatiales	L	DNA methylase	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
CH3_k127_11658638_1	497964.CfE428DRAFT_3740	4.749e-179	568.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CH3_k127_11658638_5	497964.CfE428DRAFT_3740	1.825e-15	77.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CH3_k127_11658638_0	448385.sce0471	2.339e-183	597.0	COG1414@1|root,COG1414@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	3.6.4.12	ko:K03655,ko:K10439,ko:K11708	ko02010,ko02030,ko03440,map02010,map02030,map03440	M00212,M00319	-	-	ko00000,ko00001,ko00002,ko01000,ko02000,ko03400	3.A.1.15,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	AlbA_2,HATPase_c_4,HTH_IclR,IclR,Peripla_BP_4,VCBS
CH3_k127_11658638_3	497964.CfE428DRAFT_2334	2.344e-46	172.0	COG1522@1|root,COG1522@2|Bacteria,46VEI@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24
CH3_k127_11658638_2	452637.Oter_2839	2.113e-149	482.0	COG0436@1|root,COG0436@2|Bacteria,46SFZ@74201|Verrucomicrobia,3K7B5@414999|Opitutae	414999|Opitutae	E	aminotransferase class I and II	-	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
CH3_k127_11658638_4	452637.Oter_3485	4.253e-42	157.0	COG2217@1|root,COG2217@2|Bacteria,46S53@74201|Verrucomicrobia,3K7EF@414999|Opitutae	414999|Opitutae	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,Hydrolase
CH3_k127_11659025_1	497964.CfE428DRAFT_2982	6.346e-61	219.0	COG1595@1|root,COG1595@2|Bacteria,46V3P@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
CH3_k127_11659025_0	1396418.BATQ01000010_gene3751	1.554e-199	679.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,46UAE@74201|Verrucomicrobia,2IV44@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_12,WD40
CH3_k127_11659025_3	449447.MAE_09140	4.241e-17	83.0	COG1724@1|root,COG1724@2|Bacteria,1G8K9@1117|Cyanobacteria	1117|Cyanobacteria	N	PFAM YcfA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
CH3_k127_11659025_2	679926.Mpet_1167	4.531e-28	123.0	COG1598@1|root,arCOG02411@2157|Archaea,2Y1KD@28890|Euryarchaeota,2NB9U@224756|Methanomicrobia	224756|Methanomicrobia	S	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
CH3_k127_11659813_3	237368.SCABRO_01075	5.125e-32	137.0	2AKTZ@1|root,31BM1@2|Bacteria,2J2UU@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_11659813_4	247490.KSU1_B0259	2.521e-24	117.0	COG3381@1|root,COG3381@2|Bacteria,2J3EZ@203682|Planctomycetes	203682|Planctomycetes	S	Nitrate reductase delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_del
CH3_k127_11659813_1	330214.NIDE3236	2.035e-176	563.0	COG1140@1|root,COG1140@2|Bacteria,3J1FU@40117|Nitrospirae	2|Bacteria	C	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	ddhB	GO:0005575,GO:0005623,GO:0042597,GO:0044464	1.7.5.1	ko:K00371,ko:K16965,ko:K17048,ko:K17051	ko00642,ko00910,ko00920,ko01100,ko01120,ko01220,ko02020,map00642,map00910,map00920,map01100,map01120,map01220,map02020	M00529,M00530,M00804	R00798,R01106,R05745,R09497,R09500	RC00275,RC02555,RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	5.A.3.1,5.A.3.8,5.A.3.9	-	-	Fer4_11
CH3_k127_11659813_5	1131269.AQVV01000004_gene610	8.333e-05	51.0	COG0760@1|root,COG0760@2|Bacteria	2|Bacteria	O	peptidyl-prolyl cis-trans isomerase activity	-	-	5.2.1.8	ko:K01802,ko:K03770,ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
CH3_k127_11659813_0	247490.KSU1_D0577	0.0	1562.0	COG0243@1|root,COG0243@2|Bacteria,2J2QN@203682|Planctomycetes	203682|Planctomycetes	C	Molybdopterin oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Molybdopterin
CH3_k127_11659813_2	1379698.RBG1_1C00001G0011	6.736e-126	421.0	COG2010@1|root,COG2180@1|root,COG2010@2|Bacteria,COG2180@2|Bacteria,2NR8D@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome c	narJ	GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057	-	ko:K00373,ko:K00405,ko:K17052	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko02000	3.D.4.3,5.A.3.8	-	iE2348C_1286.E2348C_1350,iECABU_c1320.ECABU_c15020,iECIAI1_1343.ECIAI1_1469,iECO103_1326.ECO103_1331,iECO111_1330.ECO111_1557,iECW_1372.ECW_m1594,iEKO11_1354.EKO11_2354,iLF82_1304.LF82_1462,iNRG857_1313.NRG857_06280,iSSON_1240.SSON_1659,iWFL_1372.ECW_m1594,ic_1306.c1687	Nitrate_red_del
CH3_k127_11707934_1	635013.TherJR_0274	1.646e-17	89.0	COG3688@1|root,COG3688@2|Bacteria,1V9XR@1239|Firmicutes,24MPI@186801|Clostridia,261WW@186807|Peptococcaceae	186801|Clostridia	S	YacP-like NYN domain	-	-	-	ko:K06962	-	-	-	-	ko00000	-	-	-	NYN_YacP
CH3_k127_11707934_0	1210884.HG799466_gene12649	4.446e-104	344.0	COG1131@1|root,COG1131@2|Bacteria,2IY1H@203682|Planctomycetes	203682|Planctomycetes	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CH3_k127_11707934_2	1123508.JH636441_gene3735	3.986e-12	70.0	28IKQ@1|root,2Z8MC@2|Bacteria,2IXYY@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane
CH3_k127_11723569_3	497964.CfE428DRAFT_3745	1.486e-11	68.0	COG0761@1|root,COG0761@2|Bacteria,46SAR@74201|Verrucomicrobia	74201|Verrucomicrobia	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	lytB	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
CH3_k127_11723569_1	497964.CfE428DRAFT_2138	6.589e-90	309.0	COG1989@1|root,COG1989@2|Bacteria,46TWT@74201|Verrucomicrobia	74201|Verrucomicrobia	NOU	Type IV leader peptidase family	-	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
CH3_k127_11723569_2	1121430.JMLG01000021_gene1382	5.349e-56	207.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia,2619R@186807|Peptococcaceae	186801|Clostridia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
CH3_k127_11723569_0	481448.Minf_1203	6.938e-137	439.0	COG0174@1|root,COG0174@2|Bacteria,46UCU@74201|Verrucomicrobia,37FVD@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	E	Glutamine synthetase, catalytic domain	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
CH3_k127_11732232_1	335543.Sfum_1457	2.713e-214	684.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJVV@28221|Deltaproteobacteria,2MR4N@213462|Syntrophobacterales	28221|Deltaproteobacteria	V	Protein export membrane protein	bepE	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
CH3_k127_11732232_3	204669.Acid345_4072	5.307e-122	412.0	COG1538@1|root,COG1538@2|Bacteria,3Y2NR@57723|Acidobacteria,2JHZY@204432|Acidobacteriia	204432|Acidobacteriia	MU	TIGRFAM RND efflux system, outer membrane lipoprotein, NodT	-	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	OEP
CH3_k127_11732232_2	1403819.BATR01000067_gene2010	4.824e-148	472.0	COG2326@1|root,COG2326@2|Bacteria,46UWN@74201|Verrucomicrobia,2IVFJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
CH3_k127_11732232_7	1121403.AUCV01000010_gene1383	1.824e-46	177.0	COG0834@1|root,COG0834@2|Bacteria,1MWDK@1224|Proteobacteria,42NVT@68525|delta/epsilon subdivisions,2WIRY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	ET	PFAM Extracellular solute-binding protein, family 3	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
CH3_k127_11732232_5	870187.Thini_1169	7.806e-72	252.0	COG0589@1|root,COG0589@2|Bacteria,1N5Z8@1224|Proteobacteria	1224|Proteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CH3_k127_11732232_10	1336233.JAEH01000025_gene1035	4.658e-08	63.0	28NM7@1|root,2ZBMT@2|Bacteria,1R9Y9@1224|Proteobacteria,1S227@1236|Gammaproteobacteria,2Q9HF@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2959)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2959
CH3_k127_11732232_6	1088869.GMO_02930	1.405e-49	188.0	COG3324@1|root,COG3324@2|Bacteria,1R81W@1224|Proteobacteria	1224|Proteobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
CH3_k127_11732232_9	247490.KSU1_C1448	6.357e-31	130.0	2CA7I@1|root,30E5G@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_11732232_8	909663.KI867150_gene2890	9.468e-43	173.0	COG3064@1|root,COG3064@2|Bacteria,1MXPS@1224|Proteobacteria,42PA3@68525|delta/epsilon subdivisions,2WM6X@28221|Deltaproteobacteria,2MQSC@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Protein of unknown function (DUF3300)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3300
CH3_k127_11732232_4	909663.KI867150_gene2891	1.704e-80	280.0	COG4786@1|root,COG4786@2|Bacteria,1MZXB@1224|Proteobacteria,42MTK@68525|delta/epsilon subdivisions,2WM8U@28221|Deltaproteobacteria,2MQWV@213462|Syntrophobacterales	28221|Deltaproteobacteria	N	Protein of unknown function (DUF2950)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2950
CH3_k127_11732232_0	1396141.BATP01000001_gene5389	5.157e-231	727.0	COG0659@1|root,COG0659@2|Bacteria,46TUB@74201|Verrucomicrobia,2IVJF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Sulfate permease family	-	-	-	-	-	-	-	-	-	-	-	-	STAS,Sulfate_transp
CH3_k127_11740016_1	886293.Sinac_7042	6.538e-95	319.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,2IX73@203682|Planctomycetes	203682|Planctomycetes	C	PFAM PBS lyase HEAT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,HEAT_2
CH3_k127_11740016_2	1121447.JONL01000003_gene3289	8.548e-11	72.0	COG0457@1|root,COG0457@2|Bacteria,1NNP4@1224|Proteobacteria,42VPE@68525|delta/epsilon subdivisions,2WRZ3@28221|Deltaproteobacteria,2MBFM@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TAtT
CH3_k127_11740016_0	573413.Spirs_4003	2.107e-190	616.0	COG0188@1|root,COG0188@2|Bacteria,2J5Y9@203691|Spirochaetes	203691|Spirochaetes	L	Belongs to the type II topoisomerase GyrA ParC subunit family	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_topoisoIV
CH3_k127_11748724_17	95619.PM1_0226610	1.546e-17	84.0	COG2314@1|root,COG2314@2|Bacteria,1RHUU@1224|Proteobacteria,1S694@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	TM2
CH3_k127_11748724_11	478741.JAFS01000001_gene1060	1.216e-25	114.0	COG2026@1|root,COG2026@2|Bacteria,46Z14@74201|Verrucomicrobia,37H0T@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	DJ	Addiction module toxin, RelE StbE family	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_11748724_3	497964.CfE428DRAFT_0539	5.094e-96	317.0	COG1403@1|root,COG1403@2|Bacteria,46SMP@74201|Verrucomicrobia	74201|Verrucomicrobia	L	HNH endonuclease	mcrA	-	-	-	-	-	-	-	-	-	-	-	HNH_5
CH3_k127_11748724_7	497964.CfE428DRAFT_2063	4.438e-35	137.0	COG0736@1|root,COG0736@2|Bacteria,46T5U@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
CH3_k127_11748724_5	497964.CfE428DRAFT_2062	2.791e-77	272.0	COG0854@1|root,COG0854@2|Bacteria,46SJT@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	-	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
CH3_k127_11748724_16	903814.ELI_3081	1.987e-18	92.0	COG1408@1|root,COG5652@1|root,COG1408@2|Bacteria,COG5652@2|Bacteria,1UU17@1239|Firmicutes,248PS@186801|Clostridia,25X0Z@186806|Eubacteriaceae	186801|Clostridia	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
CH3_k127_11748724_18	383372.Rcas_3433	9.319e-15	84.0	COG0658@1|root,COG0658@2|Bacteria,2G6G7@200795|Chloroflexi,375B1@32061|Chloroflexia	32061|Chloroflexia	S	PFAM ComEC Rec2-related protein	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131
CH3_k127_11748724_6	883126.HMPREF9710_02976	8.882e-48	175.0	COG1539@1|root,COG1539@2|Bacteria,1QVAP@1224|Proteobacteria,2WHHJ@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Putative molybdenum carrier	-	-	-	-	-	-	-	-	-	-	-	-	MoCo_carrier
CH3_k127_11748724_12	497964.CfE428DRAFT_2383	9.873e-25	109.0	2F78F@1|root,33ZPQ@2|Bacteria,46VT2@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_11748724_14	794903.OPIT5_04595	5.335e-22	99.0	COG1396@1|root,COG1396@2|Bacteria,46WYF@74201|Verrucomicrobia,3K9Q1@414999|Opitutae	414999|Opitutae	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
CH3_k127_11748724_0	478741.JAFS01000001_gene2217	3.516e-295	924.0	COG0507@1|root,COG0507@2|Bacteria,46USC@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Helix-hairpin-helix containing domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
CH3_k127_11748724_19	153721.MYP_4858	3.779e-13	80.0	COG4733@1|root,COG4733@2|Bacteria,4NTXR@976|Bacteroidetes,47SSC@768503|Cytophagia	976|Bacteroidetes	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Laminin_G_3
CH3_k127_11748724_13	880073.Calab_0118	3.699e-24	118.0	COG2911@1|root,COG4733@1|root,COG2911@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.2.1.89	ko:K01224,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000	-	-	-	DctA-YdbH,Laminin_G_3
CH3_k127_11748724_10	7739.XP_002608621.1	2.14e-26	125.0	KOG1215@1|root,KOG1215@2759|Eukaryota,38B6M@33154|Opisthokonta,3B9HR@33208|Metazoa,3CTYV@33213|Bilateria,47YVC@7711|Chordata	33208|Metazoa	T	positive regulation of presynaptic membrane organization	LRP4	GO:0000902,GO:0000904,GO:0001655,GO:0001822,GO:0001932,GO:0001934,GO:0001941,GO:0001942,GO:0003002,GO:0003674,GO:0004888,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0007154,GO:0007165,GO:0007166,GO:0007267,GO:0007275,GO:0007389,GO:0007399,GO:0007416,GO:0007528,GO:0008104,GO:0008150,GO:0008544,GO:0009653,GO:0009790,GO:0009798,GO:0009887,GO:0009888,GO:0009893,GO:0009950,GO:0009953,GO:0009954,GO:0009966,GO:0009968,GO:0009986,GO:0009987,GO:0010562,GO:0010604,GO:0010646,GO:0010648,GO:0010721,GO:0010769,GO:0010771,GO:0010975,GO:0010977,GO:0014069,GO:0016020,GO:0016043,GO:0016055,GO:0016358,GO:0017147,GO:0019220,GO:0019222,GO:0019899,GO:0019900,GO:0019901,GO:0022008,GO:0022404,GO:0022405,GO:0022603,GO:0022604,GO:0022607,GO:0023051,GO:0023052,GO:0023057,GO:0030030,GO:0030111,GO:0030154,GO:0030178,GO:0030182,GO:0030278,GO:0030279,GO:0030326,GO:0030424,GO:0030425,GO:0030971,GO:0031175,GO:0031323,GO:0031325,GO:0031344,GO:0031345,GO:0031399,GO:0031401,GO:0031594,GO:0032268,GO:0032270,GO:0032279,GO:0032501,GO:0032502,GO:0032879,GO:0032880,GO:0032989,GO:0032990,GO:0032991,GO:0033036,GO:0033267,GO:0034185,GO:0034613,GO:0035107,GO:0035108,GO:0035113,GO:0036477,GO:0038023,GO:0040007,GO:0042303,GO:0042325,GO:0042327,GO:0042475,GO:0042476,GO:0042633,GO:0042733,GO:0042802,GO:0042803,GO:0042813,GO:0042995,GO:0043005,GO:0043025,GO:0043113,GO:0043226,GO:0043235,GO:0043588,GO:0043679,GO:0043933,GO:0044085,GO:0044091,GO:0044297,GO:0044306,GO:0044332,GO:0044425,GO:0044456,GO:0044459,GO:0044463,GO:0044464,GO:0045202,GO:0045595,GO:0045596,GO:0045664,GO:0045665,GO:0045937,GO:0046983,GO:0048468,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048589,GO:0048598,GO:0048666,GO:0048667,GO:0048699,GO:0048731,GO:0048736,GO:0048812,GO:0048813,GO:0048856,GO:0048858,GO:0048869,GO:0050730,GO:0050731,GO:0050767,GO:0050768,GO:0050770,GO:0050771,GO:0050789,GO:0050793,GO:0050794,GO:0050803,GO:0050807,GO:0050808,GO:0050896,GO:0051093,GO:0051124,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051259,GO:0051262,GO:0051290,GO:0051291,GO:0051641,GO:0051668,GO:0051716,GO:0051960,GO:0051961,GO:0060070,GO:0060089,GO:0060173,GO:0060255,GO:0060284,GO:0060341,GO:0060429,GO:0060828,GO:0061024,GO:0065003,GO:0065007,GO:0065008,GO:0070727,GO:0071340,GO:0071709,GO:0071840,GO:0071944,GO:0072001,GO:0072657,GO:0080090,GO:0090090,GO:0097060,GO:0097090,GO:0097104,GO:0097105,GO:0097110,GO:0097447,GO:0097458,GO:0098590,GO:0098773,GO:0098793,GO:0098794,GO:0098984,GO:0099054,GO:0099068,GO:0099172,GO:0099173,GO:0099175,GO:0099572,GO:0120025,GO:0120035,GO:0120036,GO:0120038,GO:0120039,GO:0150034,GO:0198738,GO:1901626,GO:1901628,GO:1901629,GO:1901631,GO:1903827,GO:1903829,GO:1903909,GO:1903911,GO:1904393,GO:1904395,GO:1904396,GO:1904398,GO:1905114,GO:1905475,GO:1905477,GO:1990709,GO:1990782,GO:2000026	-	ko:K20051	-	-	-	-	ko00000,ko04131	-	-	-	EGF_CA,FXa_inhibition,Ldl_recept_a,Ldl_recept_b,cEGF
CH3_k127_11748724_4	768671.ThimaDRAFT_3684	9.962e-94	316.0	COG1484@1|root,COG1484@2|Bacteria,1MWQX@1224|Proteobacteria,1RPJM@1236|Gammaproteobacteria,1WYYP@135613|Chromatiales	135613|Chromatiales	L	DNA replication protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
CH3_k127_11748724_1	1121405.dsmv_0890	1.429e-174	562.0	COG4584@1|root,COG4584@2|Bacteria,1MWIV@1224|Proteobacteria,42MF0@68525|delta/epsilon subdivisions,2WMC1@28221|Deltaproteobacteria,2MIDP@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Transposase for insertion sequences IS1326 IS1353 (IS21 IS408 IS1162 family protein)	-	-	-	-	-	-	-	-	-	-	-	-	rve
CH3_k127_11748724_9	555779.Dthio_PD3610	1.061e-30	126.0	2E0F6@1|root,32W1G@2|Bacteria,1N6I3@1224|Proteobacteria,42V01@68525|delta/epsilon subdivisions,2WQWS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_11748724_8	218284.CCDN010000001_gene723	3.367e-32	143.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,4H9M4@91061|Bacilli,1ZBWR@1386|Bacillus	91061|Bacilli	S	Competence protein ComEC	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
CH3_k127_11748724_2	368408.Tpen_1559	3.019e-126	425.0	COG2407@1|root,arCOG01772@2157|Archaea	2157|Archaea	G	L-fucose isomerase and related	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_11748724_15	641524.ADICYQ_1594	6.059e-22	105.0	COG1082@1|root,COG1082@2|Bacteria,4NFKF@976|Bacteroidetes,47P9Y@768503|Cytophagia	976|Bacteroidetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CH3_k127_11801456_17	388051.AUFE01000129_gene4953	4.673e-06	49.0	COG3335@1|root,COG3335@2|Bacteria,1MW7X@1224|Proteobacteria,2VMDX@28216|Betaproteobacteria,1K2WH@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Elements of external origin	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_23
CH3_k127_11801456_19	1347086.CCBA010000012_gene2030	0.0004512	44.0	2AWWM@1|root,31NU5@2|Bacteria,1TZQ8@1239|Firmicutes,4II4F@91061|Bacilli,1ZJ4J@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_11801456_16	452637.Oter_2093	2.093e-12	68.0	COG0828@1|root,COG0828@2|Bacteria,46WBR@74201|Verrucomicrobia,3K8F7@414999|Opitutae	414999|Opitutae	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
CH3_k127_11801456_8	497964.CfE428DRAFT_1667	6.254e-75	262.0	COG1082@1|root,COG1082@2|Bacteria,46SWH@74201|Verrucomicrobia	74201|Verrucomicrobia	G	PFAM Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CH3_k127_11801456_5	1396418.BATQ01000091_gene5765	1.431e-124	415.0	COG0617@1|root,COG0617@2|Bacteria,46S8B@74201|Verrucomicrobia,2ITTG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Poly A polymerase head domain	-	-	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
CH3_k127_11801456_2	382464.ABSI01000010_gene3676	1.026e-153	499.0	COG2204@1|root,COG2204@2|Bacteria,46SDB@74201|Verrucomicrobia,2IU0F@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Sigma54_activat
CH3_k127_11801456_11	391623.TERMP_00885	1.29e-46	178.0	COG0463@1|root,arCOG00895@2157|Archaea,2Y66T@28890|Euryarchaeota,2454F@183968|Thermococci	183968|Thermococci	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CH3_k127_11801456_18	47839.CCAU010000018_gene4176	0.000313	53.0	COG2244@1|root,COG2244@2|Bacteria,2I8M1@201174|Actinobacteria,2372Z@1762|Mycobacteriaceae	201174|Actinobacteria	S	polysaccharide biosynthetic process	-	GO:0005575,GO:0005576	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_11801456_7	479434.Sthe_2210	1.556e-75	267.0	COG0624@1|root,COG0624@2|Bacteria,2G8FI@200795|Chloroflexi,27XZ7@189775|Thermomicrobia	200795|Chloroflexi	E	TIGRFAM acetylornithine deacetylase or succinyl- diaminopimelate desuccinylase	-	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
CH3_k127_11801456_6	1232410.KI421415_gene3062	1.871e-103	345.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,42MWH@68525|delta/epsilon subdivisions,2WJMZ@28221|Deltaproteobacteria,43U74@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Polysaccharide biosynthesis protein	uge	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
CH3_k127_11801456_3	880070.Cycma_3617	6.937e-129	434.0	2DBT1@1|root,2ZAV2@2|Bacteria,4NK57@976|Bacteroidetes,47XPG@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_11801456_4	497964.CfE428DRAFT_2622	1.261e-127	414.0	COG0152@1|root,COG0152@2|Bacteria,46SIP@74201|Verrucomicrobia	74201|Verrucomicrobia	F	SAICAR synthetase	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
CH3_k127_11801456_10	1122149.BACN01000037_gene1000	3.565e-66	238.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,4HAEX@91061|Bacilli,3F3V9@33958|Lactobacillaceae	91061|Bacilli	D	recombinase XerD	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
CH3_k127_11801456_14	498761.HM1_0137	1.75e-26	128.0	COG1470@1|root,COG3210@1|root,COG4733@1|root,COG4886@1|root,COG5492@1|root,COG1470@2|Bacteria,COG3210@2|Bacteria,COG4733@2|Bacteria,COG4886@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_2,CHU_C,Flg_new,LRR_5,RCC1,SLH
CH3_k127_11801456_9	886293.Sinac_4934	1.069e-70	271.0	COG3420@1|root,COG3420@2|Bacteria,2J2YS@203682|Planctomycetes	203682|Planctomycetes	P	antibiotic catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_11801456_15	661367.LLO_1892	4.837e-25	123.0	COG3250@1|root,COG4733@1|root,COG5492@1|root,COG3250@2|Bacteria,COG4733@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Malectin,fn3
CH3_k127_11801456_1	1232410.KI421425_gene1538	2.327e-165	545.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,42R8H@68525|delta/epsilon subdivisions,2WMWF@28221|Deltaproteobacteria,43T80@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	PEGA,Plug,TonB_dep_Rec
CH3_k127_11801456_12	269799.Gmet_1668	6.281e-44	166.0	2E3CB@1|root,32YBM@2|Bacteria,1N6WD@1224|Proteobacteria,42UIS@68525|delta/epsilon subdivisions,2WR4F@28221|Deltaproteobacteria,43VIR@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4154)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4154
CH3_k127_11801456_0	497964.CfE428DRAFT_6499	8.199e-177	584.0	COG0745@1|root,COG4191@1|root,COG0745@2|Bacteria,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,MEDS,PAS_4,PAS_9,Response_reg
CH3_k127_11801456_13	497964.CfE428DRAFT_0286	4.227e-41	154.0	2DR28@1|root,339V9@2|Bacteria	2|Bacteria	S	Stress responsive A/B Barrel Domain	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
CH3_k127_11801790_3	1123508.JH636439_gene975	1.619e-13	85.0	COG2010@1|root,COG2010@2|Bacteria,2IXQE@203682|Planctomycetes	203682|Planctomycetes	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
CH3_k127_11801790_0	1235803.C825_03594	2.551e-283	912.0	COG1262@1|root,COG1262@2|Bacteria,4NKT6@976|Bacteroidetes,2FR3S@200643|Bacteroidia	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
CH3_k127_11801790_1	1288963.ADIS_4732	2.925e-120	392.0	COG3622@1|root,COG3622@2|Bacteria,4NG0V@976|Bacteroidetes,47M10@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the hyi family	-	-	5.3.1.22	ko:K01816	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
CH3_k127_11801790_2	521674.Plim_0128	5.027e-99	330.0	COG2960@1|root,COG2960@2|Bacteria,2IX6K@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
CH3_k127_11816929_2	497964.CfE428DRAFT_0327	2.169e-11	72.0	COG1361@1|root,COG1404@1|root,COG4733@1|root,COG1361@2|Bacteria,COG1404@2|Bacteria,COG4733@2|Bacteria,46UDB@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Domain of unknown function (DUF5122) beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	ASH,DUF5122
CH3_k127_11816929_0	497964.CfE428DRAFT_5643	0.0	1090.0	COG3391@1|root,COG3391@2|Bacteria,46SN2@74201|Verrucomicrobia	74201|Verrucomicrobia	M	phospholipase C	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase,Phosphoesterase
CH3_k127_11816929_1	575540.Isop_3282	1.638e-113	388.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,2IX33@203682|Planctomycetes	203682|Planctomycetes	M	Tricorn protease C1 domain	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
CH3_k127_11823722_0	522306.CAP2UW1_1124	1.609e-207	652.0	COG0446@1|root,COG0607@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,1NR3M@1224|Proteobacteria,2VJKF@28216|Betaproteobacteria	28216|Betaproteobacteria	P	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DrsE_2,Pyr_redox_2,Pyr_redox_dim,Rhodanese,TusA
CH3_k127_11823722_3	525897.Dbac_1089	1.455e-35	148.0	2E9FY@1|root,333P7@2|Bacteria,1N8S6@1224|Proteobacteria,42XWP@68525|delta/epsilon subdivisions,2WSIE@28221|Deltaproteobacteria,2MFM6@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_11823722_6	867900.Celly_2557	0.0002861	52.0	2DPE1@1|root,331PZ@2|Bacteria,4NV5C@976|Bacteroidetes,1I5A4@117743|Flavobacteriia,1F9J7@104264|Cellulophaga	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_11823722_2	1121875.KB907547_gene2994	7.496e-53	193.0	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CH3_k127_11823722_4	1267533.KB906738_gene2202	3.988e-31	130.0	COG2197@1|root,COG2197@2|Bacteria,3Y8R3@57723|Acidobacteria,2JNDY@204432|Acidobacteriia	204432|Acidobacteriia	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CH3_k127_11823722_1	330214.NIDE3247	1.336e-60	218.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	GerE,Response_reg
CH3_k127_11823722_5	1267534.KB906754_gene2938	1.059e-24	106.0	COG2984@1|root,COG4585@1|root,COG2984@2|Bacteria,COG4585@2|Bacteria,3Y6H9@57723|Acidobacteria,2JM2H@204432|Acidobacteriia	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07683	ko02020,map02020	M00483	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA,HisKA_3,PAS_3,PAS_9
CH3_k127_11826563_12	240016.ABIZ01000001_gene2859	1.305e-12	70.0	COG0477@1|root,COG2814@2|Bacteria,46V8K@74201|Verrucomicrobia,2IUV3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EGP	Nucleoside H+ symporter	-	-	-	-	-	-	-	-	-	-	-	-	Nuc_H_symport
CH3_k127_11826563_8	1121440.AUMA01000008_gene860	4.292e-66	241.0	COG1835@1|root,COG1835@2|Bacteria,1MYXY@1224|Proteobacteria,42VFT@68525|delta/epsilon subdivisions,2WRGM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
CH3_k127_11826563_4	497964.CfE428DRAFT_5265	2.38e-80	282.0	2E1EI@1|root,32WTG@2|Bacteria,46T04@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_11826563_1	661478.OP10G_3197	2.055e-106	366.0	28MB8@1|root,2ZAPS@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_11826563_0	497964.CfE428DRAFT_2917	6.833e-149	483.0	COG0015@1|root,COG0015@2|Bacteria,46UUE@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Adenylosuccinate lyase C-terminus	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
CH3_k127_11826563_7	1304872.JAGC01000005_gene2041	4.908e-72	259.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42NHG@68525|delta/epsilon subdivisions,2WKFP@28221|Deltaproteobacteria,2M7SS@213115|Desulfovibrionales	28221|Deltaproteobacteria	NU	PFAM Type II secretion system protein E	-	-	-	-	-	-	-	-	-	-	-	-	T2SSE
CH3_k127_11826563_9	1499967.BAYZ01000089_gene5033	6.298e-54	200.0	COG0705@1|root,COG0705@2|Bacteria	2|Bacteria	S	proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
CH3_k127_11826563_10	1396418.BATQ01000046_gene6161	3.968e-41	164.0	COG0705@1|root,COG0705@2|Bacteria,46W15@74201|Verrucomicrobia,2IUFI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
CH3_k127_11826563_6	1303518.CCALI_00781	4.474e-73	258.0	COG1477@1|root,COG1477@2|Bacteria	2|Bacteria	H	protein flavinylation	apbE_1	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
CH3_k127_11826563_5	1303518.CCALI_00782	3.557e-78	278.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,TAT_signal
CH3_k127_11826563_2	1122605.KB893625_gene1943	9.441e-105	356.0	COG0399@1|root,COG0399@2|Bacteria,4NG9W@976|Bacteroidetes,1IUUU@117747|Sphingobacteriia	976|Bacteroidetes	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
CH3_k127_11826563_11	999541.bgla_1g01550	3.714e-27	130.0	COG3250@1|root,COG3250@2|Bacteria,1QZHW@1224|Proteobacteria,2WI8K@28216|Betaproteobacteria,1KIR6@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Domain of unknown function (DUF4982)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4982,F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_64,I-set
CH3_k127_11826563_13	349521.HCH_01827	8.858e-08	66.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CH3_k127_11826563_3	402777.KB235903_gene2334	7.621e-96	353.0	COG1649@1|root,COG1649@2|Bacteria,1G42C@1117|Cyanobacteria,1H72B@1150|Oscillatoriales	1117|Cyanobacteria	S	Glycosyl hydrolase-like 10	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
CH3_k127_11856319_3	1121403.AUCV01000014_gene4604	4.352e-90	308.0	COG3420@1|root,COG3420@2|Bacteria,1NIRV@1224|Proteobacteria	1224|Proteobacteria	P	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
CH3_k127_11856319_4	575540.Isop_2194	1.015e-31	137.0	COG0388@1|root,COG0388@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	-	-	3.4.13.22	ko:K08641,ko:K11206	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	CN_hydrolase,Peptidase_M15
CH3_k127_11856319_5	243090.RB4769	2.618e-12	78.0	28MMN@1|root,2ZAXE@2|Bacteria,2IY1P@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_11856319_1	471854.Dfer_2296	4.549e-110	387.0	COG2152@1|root,COG2152@2|Bacteria,4P1IV@976|Bacteroidetes	976|Bacteroidetes	G	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_11856319_0	661478.OP10G_4223	1.052e-196	641.0	COG3754@1|root,COG3754@2|Bacteria	2|Bacteria	M	Rhamnan synthesis protein F	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_WbsX,RgpF
CH3_k127_11856319_2	497964.CfE428DRAFT_1032	1.149e-100	338.0	COG3170@1|root,COG3170@2|Bacteria,46W02@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_11899416_3	1123242.JH636434_gene4117	8.876e-49	179.0	COG1520@1|root,COG1520@2|Bacteria,2IXN8@203682|Planctomycetes	203682|Planctomycetes	S	serine threonine protein kinase afsK	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
CH3_k127_11899416_2	497964.CfE428DRAFT_0226	1.547e-50	185.0	COG0663@1|root,COG0663@2|Bacteria	2|Bacteria	G	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
CH3_k127_11899416_0	204669.Acid345_1044	1.645e-92	313.0	COG2220@1|root,COG2220@2|Bacteria,3Y2TV@57723|Acidobacteria,2JHT8@204432|Acidobacteriia	204432|Acidobacteriia	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
CH3_k127_11899416_1	278963.ATWD01000001_gene3347	3.267e-85	298.0	COG5434@1|root,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBM-like,F5_F8_type_C,Pectate_lyase_3
CH3_k127_11899416_4	1304866.K413DRAFT_1088	6.915e-40	159.0	COG0457@1|root,COG0457@2|Bacteria,1TPP8@1239|Firmicutes,24B55@186801|Clostridia,36G25@31979|Clostridiaceae	186801|Clostridia	S	Domain of unknown function (DUF5107)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5107,TPR_12,TPR_16,TPR_2,TPR_8
CH3_k127_11907291_3	452637.Oter_1909	2.943e-35	143.0	COG3595@1|root,COG3595@2|Bacteria,46W0J@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
CH3_k127_11907291_2	439235.Dalk_3988	3.666e-36	143.0	COG3809@1|root,COG3809@2|Bacteria,1QSA6@1224|Proteobacteria	1224|Proteobacteria	S	Transcription factor zinc-finger	-	-	-	ko:K09981	-	-	-	-	ko00000	-	-	-	zf-TFIIB
CH3_k127_11907291_0	1183438.GKIL_2151	2.836e-210	689.0	COG1228@1|root,COG1228@2|Bacteria	2|Bacteria	Q	imidazolonepropionase activity	-	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
CH3_k127_11907291_1	1183438.GKIL_2152	5.471e-98	336.0	COG1228@1|root,COG1228@2|Bacteria	2|Bacteria	Q	imidazolonepropionase activity	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
CH3_k127_11927432_4	1123242.JH636435_gene830	1.791e-13	78.0	COG2165@1|root,COG2165@2|Bacteria,2J4W1@203682|Planctomycetes	203682|Planctomycetes	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CH3_k127_11927432_0	1123242.JH636434_gene5136	1.566e-246	774.0	COG1960@1|root,COG1960@2|Bacteria,2IXMD@203682|Planctomycetes	2|Bacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	fadE	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CH3_k127_11927432_3	452637.Oter_2330	2.181e-67	244.0	COG2972@1|root,COG2972@2|Bacteria,46XGC@74201|Verrucomicrobia,3K8E3@414999|Opitutae	414999|Opitutae	T	Signal transduction histidine kinase, LytS	-	-	2.7.13.3	ko:K02478	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,His_kinase
CH3_k127_11927432_1	1122604.JONR01000033_gene34	6.066e-75	259.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,1RMJJ@1236|Gammaproteobacteria,1X4GZ@135614|Xanthomonadales	135614|Xanthomonadales	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
CH3_k127_11927432_2	530564.Psta_2300	2.082e-70	255.0	COG0673@1|root,COG0673@2|Bacteria,2IX0C@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CH3_k127_11927432_6	1462527.CCDM010000002_gene685	2.525e-06	49.0	2EG8N@1|root,33A0G@2|Bacteria,1VMHK@1239|Firmicutes,4HSIH@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_11927432_5	1173020.Cha6605_5997	2.262e-11	70.0	COG1357@1|root,COG2026@1|root,COG1357@2|Bacteria,COG2026@2|Bacteria	2|Bacteria	DJ	nuclease activity	-	-	-	ko:K06218,ko:K06408	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
CH3_k127_11928107_2	1123242.JH636436_gene531	3.971e-15	74.0	COG1225@1|root,COG4409@1|root,COG4692@1|root,COG1225@2|Bacteria,COG4409@2|Bacteria,COG4692@2|Bacteria,2J06F@203682|Planctomycetes	203682|Planctomycetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
CH3_k127_11928107_0	1123508.JH636439_gene1235	7.95e-243	756.0	COG3119@1|root,COG3119@2|Bacteria,2IXQ5@203682|Planctomycetes	203682|Planctomycetes	P	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CH3_k127_11928107_1	886293.Sinac_6968	8.09e-237	753.0	COG4654@1|root,COG4654@2|Bacteria,2IX0M@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,PSCyt1,PSCyt2,PSD1
CH3_k127_11944383_5	1499967.BAYZ01000068_gene1943	2.108e-10	73.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,2NRIW@2323|unclassified Bacteria	2|Bacteria	S	Outer membrane lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	PEGA,TPR_16,TPR_6,TPR_8
CH3_k127_11944383_0	497964.CfE428DRAFT_0324	0.0	1223.0	COG0178@1|root,COG0178@2|Bacteria,46SEB@74201|Verrucomicrobia	74201|Verrucomicrobia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
CH3_k127_11944383_1	1396141.BATP01000029_gene2231	1.305e-159	541.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
CH3_k127_11944383_3	497964.CfE428DRAFT_5731	4.263e-61	220.0	COG2197@1|root,COG2197@2|Bacteria,46UBU@74201|Verrucomicrobia	74201|Verrucomicrobia	T	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CH3_k127_11944383_2	1396141.BATP01000028_gene2285	1.083e-84	317.0	COG4412@1|root,COG5306@1|root,COG4412@2|Bacteria,COG5306@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	ko:K07004,ko:K09955,ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	Big_4,F5_F8_type_C,Laminin_G_3
CH3_k127_11944383_4	87626.PTD2_18900	4.012e-52	185.0	COG2978@1|root,COG2978@2|Bacteria,1MUJ1@1224|Proteobacteria,1RMAI@1236|Gammaproteobacteria,2Q09W@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	H	p-aminobenzoyl-glutamate transporter	abgT	-	-	ko:K12942	-	-	-	-	ko00000	-	-	-	ABG_transport
CH3_k127_11946423_1	161156.JQKW01000013_gene170	8.88e-46	169.0	COG0190@1|root,COG0190@2|Bacteria,2GH19@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	H	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
CH3_k127_11946423_0	903818.KI912268_gene1122	0.0	1080.0	COG3383@1|root,COG3383@2|Bacteria,3Y2KP@57723|Acidobacteria	57723|Acidobacteria	C	Formate dehydrogenase, alpha subunit	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
CH3_k127_1195445_8	1380391.JIAS01000012_gene4362	2.608e-43	169.0	COG3525@1|root,COG3525@2|Bacteria,1QR2G@1224|Proteobacteria,2UDYI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	beta-N-acetylglucosaminidase	-	GO:0003674,GO:0003824,GO:0004553,GO:0004563,GO:0005975,GO:0006464,GO:0006517,GO:0006807,GO:0008150,GO:0008152,GO:0009100,GO:0009987,GO:0015929,GO:0016231,GO:0016787,GO:0016798,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901135,GO:1901564	-	-	-	-	-	-	-	-	-	-	NAGidase
CH3_k127_1195445_7	649638.Trad_0164	2.007e-52	192.0	COG0454@1|root,COG0456@2|Bacteria,1WJ43@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	PFAM Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CH3_k127_1195445_4	714943.Mucpa_7156	2.633e-99	342.0	COG1524@1|root,COG1524@2|Bacteria	2|Bacteria	S	mannose-ethanolamine phosphotransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
CH3_k127_1195445_12	1123508.JH636442_gene4113	1.774e-07	62.0	COG1413@1|root,COG1413@2|Bacteria,2J418@203682|Planctomycetes	203682|Planctomycetes	C	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
CH3_k127_1195445_13	1089553.Tph_c21120	3.504e-05	55.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,24MQK@186801|Clostridia,42GBG@68295|Thermoanaerobacterales	186801|Clostridia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
CH3_k127_1195445_11	1042163.BRLA_c034220	8.817e-18	89.0	COG3743@1|root,COG3743@2|Bacteria	2|Bacteria	S	rRNA binding	-	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	DUF4332,HHH_5,Jacalin,Ribosomal_L4
CH3_k127_1195445_3	761193.Runsl_2769	5.916e-112	375.0	COG0399@1|root,COG0399@2|Bacteria,4NE4B@976|Bacteroidetes,47M1Z@768503|Cytophagia	976|Bacteroidetes	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
CH3_k127_1195445_5	530564.Psta_3476	3.918e-99	347.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,NPCBM
CH3_k127_1195445_0	1123508.JH636445_gene6725	2.765e-231	737.0	COG1621@1|root,COG1621@2|Bacteria,2IXNN@203682|Planctomycetes	203682|Planctomycetes	G	Glycosyl hydrolases family 32	-	-	3.2.1.65,3.2.1.80	ko:K01212,ko:K03332	ko00051,ko00500,map00051,map00500	-	R00879,R05624,R11311	RC03278	ko00000,ko00001,ko01000	-	GH32	-	Glyco_hydro_32C,Glyco_hydro_32N
CH3_k127_1195445_1	886293.Sinac_2434	1.372e-156	511.0	COG2730@1|root,COG3250@1|root,COG2730@2|Bacteria,COG3250@2|Bacteria,2IZBB@203682|Planctomycetes	203682|Planctomycetes	G	Protein of unknown function (DUF4038)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF4038,DUF5060
CH3_k127_1195445_9	1396418.BATQ01000049_gene432	3.273e-39	171.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CH3_k127_1195445_10	1123508.JH636447_gene7922	1.58e-24	123.0	COG0265@1|root,COG0265@2|Bacteria,2IX93@203682|Planctomycetes	203682|Planctomycetes	O	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_1195445_2	1210884.HG799464_gene10641	7.951e-155	546.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,2IXPU@203682|Planctomycetes	203682|Planctomycetes	C	heme-binding domain, Pirellula Verrucomicrobium type	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,HEAT_2
CH3_k127_1195445_6	530564.Psta_4257	2.2e-68	267.0	COG2755@1|root,COG5306@1|root,COG2755@2|Bacteria,COG5306@2|Bacteria,2IYTG@203682|Planctomycetes	203682|Planctomycetes	E	Domain of unknown function (DUF2341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2341,Laminin_G_3,SASA
CH3_k127_11971290_10	272123.Anacy_5220	2.184e-08	66.0	COG2931@1|root,COG4625@1|root,COG2931@2|Bacteria,COG4625@2|Bacteria	2|Bacteria	T	pathogenesis	-	-	3.2.1.4	ko:K01179,ko:K07004	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Calx-beta,Laminin_G_3,PATR
CH3_k127_11971290_0	886293.Sinac_6489	2.336e-132	462.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
CH3_k127_11971290_6	497964.CfE428DRAFT_4864	2.985e-64	228.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_11971290_8	65393.PCC7424_4493	1.259e-31	129.0	COG0680@1|root,COG0680@2|Bacteria,1G7PP@1117|Cyanobacteria,3KI4D@43988|Cyanothece	1117|Cyanobacteria	C	TIGRFAM hydrogenase maturation protease	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_11971290_4	118005.AWNK01000006_gene1372	2.657e-101	341.0	COG1611@1|root,COG1611@2|Bacteria	2|Bacteria	S	cytokinin biosynthetic process	fas6	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
CH3_k127_11971290_2	1403819.BATR01000017_gene553	1.114e-107	357.0	COG1413@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2133@2|Bacteria,46Z8S@74201|Verrucomicrobia,2IWNA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CG	NPCBM/NEW2 domain	-	-	-	-	-	-	-	-	-	-	-	-	NPCBM,ThuA
CH3_k127_11971290_5	1403819.BATR01000017_gene559	5.992e-85	295.0	COG2133@1|root,COG2133@2|Bacteria,46UM9@74201|Verrucomicrobia,2IVKI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CH3_k127_11971290_1	497964.CfE428DRAFT_4760	9.548e-126	407.0	COG1082@1|root,COG1082@2|Bacteria,46SWE@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CH3_k127_11971290_7	525904.Tter_0015	4.858e-51	205.0	COG1253@1|root,COG1253@2|Bacteria,2NP9I@2323|unclassified Bacteria	2|Bacteria	S	Transporter associated domain	tlyC	-	-	ko:K06189	-	-	-	-	ko00000,ko02000	9.A.40.1.2	-	-	CBS,CorC_HlyC,DUF21
CH3_k127_11971290_9	497964.CfE428DRAFT_0673	5.115e-23	112.0	COG1253@1|root,COG1253@2|Bacteria,46W8Q@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function DUF21	-	-	-	-	-	-	-	-	-	-	-	-	DUF21
CH3_k127_11971290_3	696281.Desru_1739	2.908e-104	353.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,26052@186807|Peptococcaceae	186801|Clostridia	S	CBS domain-containing protein	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
CH3_k127_11971290_11	28444.JODQ01000003_gene4977	8.606e-08	62.0	COG2324@1|root,COG2324@2|Bacteria,2IIUJ@201174|Actinobacteria,4EIUK@85012|Streptosporangiales	201174|Actinobacteria	S	Carotenoid biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Caroten_synth
CH3_k127_11989351_0	289376.THEYE_A0114	1.265e-166	531.0	COG0473@1|root,COG0473@2|Bacteria,3J0JQ@40117|Nitrospirae	40117|Nitrospirae	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
CH3_k127_12007654_1	452637.Oter_0554	2.547e-190	605.0	COG1236@1|root,COG1236@2|Bacteria,46UFS@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
CH3_k127_12007654_0	1396141.BATP01000042_gene1909	2.715e-248	785.0	COG3829@1|root,COG3829@2|Bacteria,46UZT@74201|Verrucomicrobia,2IVHE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	Sigma54_activat
CH3_k127_12007654_2	1396141.BATP01000042_gene1908	5.975e-61	213.0	COG1765@1|root,COG1765@2|Bacteria	2|Bacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
CH3_k127_12019172_11	1090320.KB900605_gene3525	0.0009778	51.0	COG3250@1|root,COG3250@2|Bacteria,1NYBH@1224|Proteobacteria,2U1SW@28211|Alphaproteobacteria,2K1C6@204457|Sphingomonadales	204457|Sphingomonadales	G	Glycosyl hydrolases family 2	-	-	3.2.1.25	ko:K01192	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2
CH3_k127_12019172_6	679199.HMPREF9332_01395	5.496e-75	284.0	COG3525@1|root,COG3525@2|Bacteria,4NEQN@976|Bacteroidetes,2FMUE@200643|Bacteroidia	976|Bacteroidetes	G	F5 8 type C domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4838,F5_F8_type_C,Glyco_hydro_67N
CH3_k127_12019172_4	497964.CfE428DRAFT_3514	3.002e-116	386.0	COG3055@1|root,COG3055@2|Bacteria,46T14@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_12019172_1	1396141.BATP01000009_gene2639	3.63e-208	657.0	COG0477@1|root,COG2814@2|Bacteria,46Z9E@74201|Verrucomicrobia	74201|Verrucomicrobia	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CH3_k127_12019172_5	886293.Sinac_2107	5.799e-113	373.0	COG0329@1|root,COG0329@2|Bacteria,2IYE2@203682|Planctomycetes	203682|Planctomycetes	EM	Dihydrodipicolinate synthase N-acetylneuraminate lyase	-	-	4.1.3.3	ko:K01639	ko00520,map00520	-	R01811	RC00159,RC00600	ko00000,ko00001,ko01000	-	-	-	DHDPS
CH3_k127_12019172_2	344747.PM8797T_29708	2.794e-179	568.0	COG4409@1|root,COG4409@2|Bacteria,2IYPT@203682|Planctomycetes	2|Bacteria	G	BNR repeat-like domain	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,Big_2,DUF4091,FIVAR,Laminin_G_3
CH3_k127_12019172_3	1396418.BATQ01000150_gene2240	1.121e-173	554.0	COG2942@1|root,COG2942@2|Bacteria,46UIM@74201|Verrucomicrobia,2ITK6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)	-	-	5.1.3.8	ko:K01787	ko00520,map00520	-	R01207	RC00290	ko00000,ko00001,ko01000	-	-	-	GlcNAc_2-epim
CH3_k127_12019172_7	1303518.CCALI_02288	1.114e-48	188.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	5.1.3.22	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R03244	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	AP_endonuc_2
CH3_k127_12019172_0	344747.PM8797T_10954	2.14e-215	677.0	COG0673@1|root,COG0673@2|Bacteria,2IWX9@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CH3_k127_12019172_9	1303518.CCALI_02638	5.071e-11	73.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
CH3_k127_12019172_8	1396141.BATP01000007_gene5570	1.145e-19	96.0	COG5306@1|root,COG5306@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
CH3_k127_12025733_3	926550.CLDAP_33840	1.064e-103	346.0	COG1313@1|root,COG1313@2|Bacteria,2G65I@200795|Chloroflexi	200795|Chloroflexi	C	Radical SAM domain protein	-	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
CH3_k127_12025733_6	521674.Plim_2940	1.118e-72	252.0	COG1387@1|root,COG1387@2|Bacteria,2IZCF@203682|Planctomycetes	203682|Planctomycetes	E	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CH3_k127_12025733_9	1519464.HY22_03120	6.097e-49	181.0	COG1335@1|root,COG1335@2|Bacteria,1FE0F@1090|Chlorobi	1090|Chlorobi	Q	PFAM isochorismatase hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
CH3_k127_12025733_0	478741.JAFS01000002_gene302	3.252e-199	639.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,46TH0@74201|Verrucomicrobia,37G1H@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	L	DNA polymerase X family	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_thumb,HHH_5,HHH_8,PHP
CH3_k127_12025733_2	224911.27351242	1.204e-108	377.0	COG4191@1|root,COG4191@2|Bacteria,1NC2U@1224|Proteobacteria,2U484@28211|Alphaproteobacteria,3K3MC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,MASE3,Response_reg
CH3_k127_12025733_13	344747.PM8797T_07909	2.216e-14	85.0	COG4968@1|root,COG4968@2|Bacteria,2J519@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CH3_k127_12025733_7	1235279.C772_01648	3.406e-68	241.0	COG0351@1|root,COG0351@2|Bacteria,1TQ4A@1239|Firmicutes,4HAAH@91061|Bacilli,26DBP@186818|Planococcaceae	91061|Bacilli	H	Phosphomethylpyrimidine kinase	thiD	-	2.5.1.3,2.7.1.49,2.7.4.7	ko:K00941,ko:K14153	ko00730,ko01100,map00730,map01100	M00127	R03223,R03471,R04509,R10712	RC00002,RC00017,RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
CH3_k127_12025733_1	240016.ABIZ01000001_gene1581	5.469e-133	435.0	COG1082@1|root,COG1082@2|Bacteria,46UXT@74201|Verrucomicrobia,2ITIF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_12025733_11	1411123.JQNH01000001_gene687	5.548e-43	168.0	COG0382@1|root,COG0382@2|Bacteria,1RFNQ@1224|Proteobacteria,2U4XF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	UbiA prenyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	UbiA
CH3_k127_12025733_4	1121904.ARBP01000012_gene1301	1.381e-101	368.0	2DBK2@1|root,2Z9Q1@2|Bacteria,4NET4@976|Bacteroidetes,47MUQ@768503|Cytophagia	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_12025733_5	1403819.BATR01000125_gene4449	3.173e-92	339.0	2CEMG@1|root,346QA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
CH3_k127_12025733_8	1123242.JH636434_gene4287	1.226e-58	233.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CH3_k127_12025733_12	722419.PH505_co00060	3.864e-33	134.0	COG3296@1|root,COG3296@2|Bacteria,1RET3@1224|Proteobacteria,1S4H0@1236|Gammaproteobacteria,2Q2CW@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4870)	-	-	-	ko:K09940	-	-	-	-	ko00000	-	-	-	DUF4870
CH3_k127_12025733_10	1185876.BN8_01837	4.001e-46	168.0	COG0279@1|root,COG0279@2|Bacteria,4NKHI@976|Bacteroidetes,47N1Y@768503|Cytophagia	976|Bacteroidetes	G	SIS domain	-	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
CH3_k127_12083006_7	118005.AWNK01000003_gene2462	1.27e-29	138.0	COG1409@1|root,COG2931@1|root,COG3209@1|root,COG5184@1|root,COG1409@2|Bacteria,COG2931@2|Bacteria,COG3209@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	DUF1735,Flg_new,Laminin_G_3,Mfa_like_1,RCC1,RCC1_2
CH3_k127_12083006_6	344747.PM8797T_11666	4.859e-56	208.0	COG1131@1|root,COG1131@2|Bacteria,2IY79@203682|Planctomycetes	203682|Planctomycetes	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CH3_k127_12083006_10	1120971.AUCA01000003_gene1386	6.285e-22	100.0	COG1725@1|root,COG1725@2|Bacteria,1VFD0@1239|Firmicutes,4HNIT@91061|Bacilli,27A9H@186823|Alicyclobacillaceae	91061|Bacilli	K	helix_turn_helix gluconate operon transcriptional repressor	ytrA	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
CH3_k127_12083006_2	497964.CfE428DRAFT_5037	3.561e-141	462.0	COG1454@1|root,COG1454@2|Bacteria,46TD9@74201|Verrucomicrobia	74201|Verrucomicrobia	C	PFAM iron-containing alcohol dehydrogenase	-	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
CH3_k127_12083006_3	768671.ThimaDRAFT_3418	8.019e-78	271.0	COG4783@1|root,COG4783@2|Bacteria,1QUMJ@1224|Proteobacteria,1T2RP@1236|Gammaproteobacteria,1WXRA@135613|Chromatiales	135613|Chromatiales	S	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
CH3_k127_12083006_0	497964.CfE428DRAFT_6179	3.576e-171	561.0	COG3875@1|root,COG3875@2|Bacteria,46TVY@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
CH3_k127_12083006_5	325452.fgenesh_scip_prom.46568.7654	3.228e-67	231.0	COG0318@1|root,COG0590@1|root,KOG1018@2759|Eukaryota,KOG1176@2759|Eukaryota,3Q9PC@4776|Peronosporales	4776|Peronosporales	I	AMP-binding enzyme C-terminal domain	-	-	-	ko:K18660	ko00280,map00280	-	R03383	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
CH3_k127_12083006_12	1403819.BATR01000031_gene994	6.007e-07	57.0	2EMM1@1|root,33F9E@2|Bacteria,46TBT@74201|Verrucomicrobia,2IUX2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_12083006_1	1396418.BATQ01000019_gene5009	5.382e-160	515.0	COG0019@1|root,COG0019@2|Bacteria,46SC5@74201|Verrucomicrobia,2ITWM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Pyridoxal-dependent decarboxylase, pyridoxal binding domain	-	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
CH3_k127_12083006_4	671143.DAMO_2922	4.327e-72	257.0	COG1562@1|root,COG1562@2|Bacteria,2NQ18@2323|unclassified Bacteria	2|Bacteria	I	Squalene/phytoene synthase	crtB	GO:0003674,GO:0003824,GO:0004337,GO:0004659,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016108,GO:0016109,GO:0016114,GO:0016116,GO:0016117,GO:0016740,GO:0016765,GO:0016767,GO:0042440,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046148,GO:0071704,GO:1901576	2.5.1.21,2.5.1.32,2.5.1.96,2.5.1.99	ko:K00801,ko:K02291,ko:K10208	ko00100,ko00906,ko00909,ko01062,ko01100,ko01110,ko01130,map00100,map00906,map00909,map01062,map01100,map01110,map01130	M00097	R00702,R02065,R02872,R04218,R06223,R07270,R07652,R09793,R10177	RC00362,RC00796,RC01101,RC02839,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
CH3_k127_12083006_11	443143.GM18_2349	2.551e-18	89.0	COG5496@1|root,COG5496@2|Bacteria,1RKFT@1224|Proteobacteria,42TER@68525|delta/epsilon subdivisions,2WPKW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Thioesterase	-	-	3.1.2.29	ko:K18700	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
CH3_k127_12083006_9	388467.A19Y_4225	4.682e-26	108.0	2CIXY@1|root,338DR@2|Bacteria,1G934@1117|Cyanobacteria,1HDGE@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_12083006_8	933262.AXAM01000130_gene757	1.13e-26	111.0	COG1598@1|root,COG1598@2|Bacteria,1P1K3@1224|Proteobacteria,431VD@68525|delta/epsilon subdivisions,2WWWI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_12095811_8	926550.CLDAP_17500	1.638e-10	68.0	COG2706@1|root,COG2931@1|root,COG5337@1|root,COG2706@2|Bacteria,COG2931@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_5,LTD,VCBS
CH3_k127_12095811_1	1502851.FG93_05342	7.814e-123	412.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2U2DK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K13487	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001	-	-	-	4HB_MCP_1,HAMP,MCPsignal
CH3_k127_12095811_6	629265.PMA4326_11447	1.795e-37	146.0	COG0835@1|root,COG0835@2|Bacteria,1N0R3@1224|Proteobacteria,1SG9X@1236|Gammaproteobacteria,1Z7ZK@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	NT	COG0835 Chemotaxis signal transduction protein	wspB	-	-	ko:K13488	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001	-	-	-	CheW
CH3_k127_12095811_3	240016.ABIZ01000001_gene190	9.573e-100	340.0	COG1352@1|root,COG1352@2|Bacteria,46U91@74201|Verrucomicrobia	74201|Verrucomicrobia	NT	Methyltransferase, chemotaxis proteins	-	-	-	-	-	-	-	-	-	-	-	-	CheR,TPR_2
CH3_k127_12095811_5	748247.AZKH_p0390	3.17e-56	205.0	COG0835@1|root,COG0835@2|Bacteria,1RIUD@1224|Proteobacteria,2VSFU@28216|Betaproteobacteria	28216|Betaproteobacteria	NT	chemotaxis signal transduction protein	wspD	-	-	ko:K13489	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001	-	-	-	CheW
CH3_k127_12095811_0	1403819.BATR01000024_gene821	1.901e-247	790.0	COG0643@1|root,COG0745@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,46UEP@74201|Verrucomicrobia,2IUVS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Two component signalling adaptor domain	-	-	-	-	-	-	-	-	-	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
CH3_k127_12095811_2	240016.ABIZ01000001_gene193	1.616e-117	388.0	COG2201@1|root,COG2201@2|Bacteria,46TVZ@74201|Verrucomicrobia,2IUSQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	NT	CheB methylesterase	-	-	-	-	-	-	-	-	-	-	-	-	CheB_methylest,Response_reg
CH3_k127_12095811_4	309807.SRU_0542	4.05e-79	274.0	COG0115@1|root,COG0115@2|Bacteria,4NI83@976|Bacteroidetes	976|Bacteroidetes	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.21	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	-	R01148,R01582,R02459,R02851,R02924,R05053	RC00006,RC00008,RC00025	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4
CH3_k127_12095811_7	497964.CfE428DRAFT_2305	7.555e-37	141.0	COG1692@1|root,COG1692@2|Bacteria,46SQ2@74201|Verrucomicrobia	74201|Verrucomicrobia	S	YmdB-like protein	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
CH3_k127_12110927_1	497964.CfE428DRAFT_5027	2.335e-50	190.0	COG1520@1|root,COG1520@2|Bacteria,46U9S@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CH3_k127_12110927_4	661478.OP10G_4109	1.019e-11	76.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02650,ko:K02679	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10
CH3_k127_12110927_2	794903.OPIT5_05580	2.242e-24	110.0	COG0597@1|root,COG0597@2|Bacteria,46TCC@74201|Verrucomicrobia,3K87P@414999|Opitutae	414999|Opitutae	M	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
CH3_k127_12110927_0	497964.CfE428DRAFT_0417	6.949e-85	291.0	COG0564@1|root,COG0564@2|Bacteria,46SQY@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
CH3_k127_12110927_3	555088.DealDRAFT_2373	8.506e-23	106.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,42K3B@68298|Syntrophomonadaceae	186801|Clostridia	K	RNA polymerase sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CH3_k127_12121388_2	1121895.Q765_20730	3.289e-12	72.0	COG1345@1|root,COG2374@1|root,COG3210@1|root,COG1345@2|Bacteria,COG2374@2|Bacteria,COG3210@2|Bacteria,4NFVP@976|Bacteroidetes,1IIIJ@117743|Flavobacteriia,2P0E0@237|Flavobacterium	976|Bacteroidetes	N	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3494,LTD
CH3_k127_12121388_1	1484460.JSWG01000009_gene629	1.439e-60	220.0	COG2356@1|root,COG2374@1|root,COG2911@1|root,COG3291@1|root,COG3391@1|root,COG2356@2|Bacteria,COG2374@2|Bacteria,COG2911@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	CHU_C,LTD,fn3
CH3_k127_12121388_0	1267533.KB906734_gene4022	1.479e-119	397.0	COG0438@1|root,COG0438@2|Bacteria,3Y5K5@57723|Acidobacteria,2JNE3@204432|Acidobacteriia	204432|Acidobacteriia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_12121388_3	715451.ambt_02285	9.605e-06	52.0	COG4969@1|root,COG4969@2|Bacteria,1N7EQ@1224|Proteobacteria,1SCES@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	Belongs to the N-Me-Phe pilin family	ppdD	GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464	-	ko:K02650,ko:K02682	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,Pilin
CH3_k127_12143791_6	497964.CfE428DRAFT_1981	2.044e-53	194.0	COG1397@1|root,COG1397@2|Bacteria	2|Bacteria	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
CH3_k127_12143791_10	1210884.HG799465_gene11759	5.583e-27	115.0	2BRR1@1|root,32KQS@2|Bacteria,2J4RN@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_12143791_3	497964.CfE428DRAFT_1980	7.639e-88	302.0	COG4295@1|root,COG4295@2|Bacteria,46TDT@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Uncharacterized protein conserved in bacteria (DUF2263)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2263
CH3_k127_12143791_1	497964.CfE428DRAFT_1983	7.263e-123	404.0	COG0061@1|root,COG0061@2|Bacteria,46UHQ@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_12143791_0	497964.CfE428DRAFT_1982	5.618e-149	484.0	COG0330@1|root,COG0330@2|Bacteria,46U2V@74201|Verrucomicrobia	74201|Verrucomicrobia	O	PFAM band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
CH3_k127_12143791_2	497964.CfE428DRAFT_1977	8.998e-114	370.0	COG1051@1|root,COG1051@2|Bacteria,46SHC@74201|Verrucomicrobia	74201|Verrucomicrobia	F	NUDIX domain	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
CH3_k127_12143791_5	997346.HMPREF9374_2103	7.417e-61	219.0	COG5113@1|root,COG3236@2|Bacteria,1V7IA@1239|Firmicutes,4HK8U@91061|Bacilli,27C7F@186824|Thermoactinomycetaceae	91061|Bacilli	O	Domain of unknown function (DUF1768)	ybiA	-	-	ko:K09935	-	-	-	-	ko00000	-	-	-	DUF1768
CH3_k127_12143791_7	452637.Oter_1044	1.637e-42	160.0	COG1397@1|root,COG1397@2|Bacteria,46VZX@74201|Verrucomicrobia	74201|Verrucomicrobia	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_12143791_8	1122918.KB907245_gene5077	1.881e-39	154.0	COG0352@1|root,COG0352@2|Bacteria,1V3ZR@1239|Firmicutes,4HH1E@91061|Bacilli,26UCZ@186822|Paenibacillaceae	91061|Bacilli	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
CH3_k127_12143791_11	317936.Nos7107_2700	2.337e-16	84.0	COG3577@1|root,COG3577@2|Bacteria	2|Bacteria	S	aspartic-type endopeptidase activity	-	-	-	ko:K06985	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	Asp_protease_2,gag-asp_proteas
CH3_k127_12143791_9	330214.NIDE1418	1.067e-38	153.0	COG1386@1|root,COG1386@2|Bacteria,3J15Z@40117|Nitrospirae	40117|Nitrospirae	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
CH3_k127_12143791_4	497964.CfE428DRAFT_5017	2.383e-70	251.0	COG1354@1|root,COG1354@2|Bacteria,46UBD@74201|Verrucomicrobia	74201|Verrucomicrobia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	-	-	-	-	-	-	-	-	-	-	-	-	SMC_ScpA
CH3_k127_12143791_12	1403819.BATR01000178_gene5964	4.774e-08	55.0	COG1520@1|root,COG1520@2|Bacteria,46TV4@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CH3_k127_12143859_2	452637.Oter_2449	3.884e-65	226.0	COG0652@1|root,COG0652@2|Bacteria,46VEN@74201|Verrucomicrobia,3K7Y9@414999|Opitutae	414999|Opitutae	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
CH3_k127_12143859_3	1125863.JAFN01000001_gene1790	3.143e-42	161.0	COG0494@1|root,COG0494@2|Bacteria,1RCX7@1224|Proteobacteria,42UR1@68525|delta/epsilon subdivisions,2WPQ1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CH3_k127_12143859_1	1396418.BATQ01000175_gene2745	3.529e-81	278.0	COG1387@1|root,COG1387@2|Bacteria,46SMB@74201|Verrucomicrobia,2IU6X@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	PHP domain	-	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
CH3_k127_12143859_0	886293.Sinac_3213	1.187e-214	684.0	COG4805@1|root,COG4805@2|Bacteria,2IXQZ@203682|Planctomycetes	203682|Planctomycetes	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
CH3_k127_12143859_4	1123276.KB893257_gene2665	5.111e-27	113.0	COG3104@1|root,COG3104@2|Bacteria,4NE8R@976|Bacteroidetes,47JX4@768503|Cytophagia	976|Bacteroidetes	E	TIGRFAM amino acid peptide transporter (Peptide H symporter), bacterial	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
CH3_k127_12151121_1	661478.OP10G_1294	5.032e-146	481.0	COG3533@1|root,COG3533@2|Bacteria	2|Bacteria	S	Beta-L-arabinofuranosidase, GH127	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	F5_F8_type_C,Glyco_hydro_127
CH3_k127_12151121_2	926550.CLDAP_13620	5.442e-145	471.0	COG1063@1|root,COG1063@2|Bacteria,2G7MF@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Alcohol dehydrogenase GroES domain protein	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_N_assoc,ADH_zinc_N
CH3_k127_12151121_0	518766.Rmar_0469	1.206e-233	734.0	COG1069@1|root,COG1069@2|Bacteria,4NEFQ@976|Bacteroidetes	976|Bacteroidetes	G	Belongs to the ribulokinase family	araB	-	2.7.1.16	ko:K00853	ko00040,ko01100,map00040,map01100	-	R01526,R02439	RC00002,RC00538	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
CH3_k127_12151121_5	1235797.C816_02559	2.01e-92	310.0	COG0235@1|root,COG0235@2|Bacteria,1TPDV@1239|Firmicutes,248KI@186801|Clostridia,2N6GG@216572|Oscillospiraceae	186801|Clostridia	G	Class II Aldolase and Adducin N-terminal domain	araD	-	5.1.3.4	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R05850	RC01479	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
CH3_k127_12151121_3	234267.Acid_1458	1.258e-140	458.0	COG2017@1|root,COG2017@2|Bacteria,3Y3D2@57723|Acidobacteria	57723|Acidobacteria	G	Converts alpha-aldose to the beta-anomer	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
CH3_k127_12151121_4	1396141.BATP01000038_gene1209	4.859e-121	394.0	COG1879@1|root,COG1879@2|Bacteria,46XDV@74201|Verrucomicrobia,2IVKX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Periplasmic binding protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_4
CH3_k127_1219304_2	443143.GM18_2872	6.709e-57	214.0	COG0286@1|root,COG0286@2|Bacteria,1MW3A@1224|Proteobacteria,42N9K@68525|delta/epsilon subdivisions,2WINH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	PFAM N-6 DNA methylase	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
CH3_k127_1219304_4	388413.ALPR1_07560	2.904e-22	110.0	2CCSR@1|root,32RWC@2|Bacteria,4NUMI@976|Bacteroidetes	976|Bacteroidetes	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
CH3_k127_1219304_5	290317.Cpha266_1712	4.172e-17	88.0	COG0286@1|root,COG0286@2|Bacteria	2|Bacteria	V	site-specific DNA-methyltransferase (adenine-specific) activity	hsdM	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
CH3_k127_1219304_0	443143.GM18_4359	1.24e-91	317.0	COG0286@1|root,COG0286@2|Bacteria,1NTF8@1224|Proteobacteria	1224|Proteobacteria	L	N-6 DNA Methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
CH3_k127_1219304_1	1500281.JQKZ01000035_gene90	3.158e-84	292.0	COG4191@1|root,COG4191@2|Bacteria,4P85X@976|Bacteroidetes,1IJVC@117743|Flavobacteriia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_3
CH3_k127_1219304_3	1210884.HG799470_gene14506	3.3e-34	145.0	COG0584@1|root,COG0584@2|Bacteria,2J1MH@203682|Planctomycetes	203682|Planctomycetes	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
CH3_k127_12195860_7	1396141.BATP01000060_gene4555	8.627e-22	109.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,46U7Q@74201|Verrucomicrobia,2ITXJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	NAD synthase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase,NAD_synthase
CH3_k127_12195860_3	1396141.BATP01000035_gene4047	7.45e-51	192.0	COG1922@1|root,COG1922@2|Bacteria,46VQJ@74201|Verrucomicrobia,2IUM7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Glycosyl transferase WecB/TagA/CpsF family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_WecB
CH3_k127_12195860_6	313606.M23134_05981	1.368e-29	128.0	COG4123@1|root,COG4123@2|Bacteria,4NKPF@976|Bacteroidetes,47SG7@768503|Cytophagia	976|Bacteroidetes	S	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
CH3_k127_12195860_4	118168.MC7420_6062	8.122e-40	164.0	COG0438@1|root,COG0438@2|Bacteria,1G0EX@1117|Cyanobacteria,1H9C2@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
CH3_k127_12195860_5	452637.Oter_0284	9.11e-33	141.0	2DT8D@1|root,33J57@2|Bacteria,46WBF@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Transmembrane exosortase (Exosortase_EpsH)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3485,Exosortase_EpsH
CH3_k127_12195860_8	240016.ABIZ01000001_gene498	6.154e-14	82.0	2DKIU@1|root,309MI@2|Bacteria,46W7D@74201|Verrucomicrobia,2IUZM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF3485)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3485
CH3_k127_12195860_1	497964.CfE428DRAFT_4614	4.224e-117	393.0	COG2148@1|root,COG2148@2|Bacteria,46TSZ@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
CH3_k127_12195860_0	497964.CfE428DRAFT_4613	4.108e-145	466.0	COG0451@1|root,COG0451@2|Bacteria,46S80@74201|Verrucomicrobia	74201|Verrucomicrobia	GM	GDP-mannose 4,6 dehydratase	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
CH3_k127_12195860_2	497964.CfE428DRAFT_4611	3.407e-97	342.0	COG4972@1|root,COG4972@2|Bacteria,46UI7@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	Type IV pilus assembly protein PilM;	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
CH3_k127_12195860_9	240016.ABIZ01000001_gene5219	1.736e-11	76.0	COG0457@1|root,COG1450@1|root,COG0457@2|Bacteria,COG1450@2|Bacteria,46TXY@74201|Verrucomicrobia,2ITGX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	NU	Bacterial type II and III secretion system protein	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin
CH3_k127_12260459_0	1396141.BATP01000056_gene3118	8.594e-119	400.0	COG0515@1|root,COG0515@2|Bacteria,46U28@74201|Verrucomicrobia,2IWN1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CH3_k127_12260459_1	382464.ABSI01000010_gene3853	1.677e-62	226.0	COG4912@1|root,COG4912@2|Bacteria	2|Bacteria	L	Dna alkylation repair	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
CH3_k127_12260459_3	452637.Oter_1848	0.000958	45.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CH3_k127_12260459_2	452637.Oter_1848	3.002e-05	48.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CH3_k127_12274300_3	497964.CfE428DRAFT_0420	1.128e-39	152.0	2AY99@1|root,31QBJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_12274300_1	1382356.JQMP01000003_gene2064	5.078e-51	193.0	COG0154@1|root,COG0154@2|Bacteria,2G7KI@200795|Chloroflexi,27YVS@189775|Thermomicrobia	189775|Thermomicrobia	J	Amidase	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
CH3_k127_12274300_2	478741.JAFS01000001_gene2028	3.382e-43	166.0	COG4798@1|root,COG4798@2|Bacteria,46T4I@74201|Verrucomicrobia,37GDY@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Met-10+ like-protein	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
CH3_k127_12274300_0	1267535.KB906767_gene1032	4.001e-96	327.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
CH3_k127_12275502_2	340177.Cag_0614	4.356e-17	95.0	COG1357@1|root,COG2931@1|root,COG3210@1|root,COG4625@1|root,COG1357@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria	2|Bacteria	T	pathogenesis	rhgB	-	4.2.2.23	ko:K07004,ko:K18195	-	-	-	-	ko00000,ko01000	-	PL4	-	CBM-like,RhgB_N,fn3_3
CH3_k127_12275502_6	1205908.AKXW01000001_gene3223	2.835e-05	52.0	COG2801@1|root,COG3415@1|root,COG2801@2|Bacteria,COG3415@2|Bacteria,1MWVQ@1224|Proteobacteria,1RN12@1236|Gammaproteobacteria,1XVDW@135623|Vibrionales	135623|Vibrionales	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	HTH_29,rve
CH3_k127_12275502_4	420324.KI911932_gene324	4.062e-16	82.0	2EHAG@1|root,3394C@2|Bacteria,1NK4E@1224|Proteobacteria,2UJZB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Family of unknown function (DUF5372)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5372
CH3_k127_12275502_1	94624.Bpet1408	3.95e-37	147.0	COG3415@1|root,COG3415@2|Bacteria,1RKUV@1224|Proteobacteria,2WFVI@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28,HTH_29
CH3_k127_12275502_0	94624.Bpet1409	7.444e-240	767.0	COG1961@1|root,COG1961@2|Bacteria,1MVIE@1224|Proteobacteria,2VK01@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Resolvase domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
CH3_k127_12275502_5	883078.HMPREF9695_00489	2.063e-06	58.0	COG2801@1|root,COG2801@2|Bacteria,1MWVQ@1224|Proteobacteria,2TQPC@28211|Alphaproteobacteria,3JZ69@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Homeodomain-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28,HTH_29,HTH_32,rve
CH3_k127_12275502_3	1380393.JHVP01000007_gene4488	7.663e-17	94.0	COG0028@1|root,COG0028@2|Bacteria	2|Bacteria	EH	Belongs to the TPP enzyme family	-	-	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	Laminin_G_3,PKD,TIG,TPP_enzyme_M,fn3
CH3_k127_12283336_2	314230.DSM3645_23076	1.336e-60	220.0	COG1520@1|root,COG1520@2|Bacteria,2IXN8@203682|Planctomycetes	203682|Planctomycetes	S	serine threonine protein kinase afsK	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
CH3_k127_12283336_1	497964.CfE428DRAFT_4864	5.459e-64	228.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_12283336_4	1396141.BATP01000060_gene4559	4.188e-34	146.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR,PSII_BNR
CH3_k127_12283336_0	1403819.BATR01000020_gene698	4.424e-190	640.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,46UAE@74201|Verrucomicrobia,2IV44@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_12,WD40
CH3_k127_12283336_3	1123023.JIAI01000001_gene6305	3.309e-46	168.0	COG2230@1|root,COG2230@2|Bacteria	2|Bacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	-	-	-	-	-	-	-	-	-	-	-	-	CMAS,Methyltransf_25
CH3_k127_12326801_3	498761.HM1_0197	1.329e-43	162.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,248JC@186801|Clostridia	186801|Clostridia	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
CH3_k127_12326801_5	1131266.ARWQ01000091_gene18	5.691e-10	63.0	arCOG07442@1|root,arCOG07442@2157|Archaea,41SWG@651137|Thaumarchaeota	651137|Thaumarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_12326801_1	497964.CfE428DRAFT_2462	3.82e-145	469.0	COG0105@1|root,COG0105@2|Bacteria,46T8K@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Nucleoside diphosphate kinase	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
CH3_k127_12326801_4	671143.DAMO_2861	4.145e-35	141.0	COG0494@1|root,COG0494@2|Bacteria,2NPUY@2323|unclassified Bacteria	2|Bacteria	L	NUDIX domain	mutY	-	3.6.1.55	ko:K03574,ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD,NUDIX,NUDIX_4
CH3_k127_12326801_0	481448.Minf_0010	6.927e-184	584.0	COG1004@1|root,COG1004@2|Bacteria,46S6E@74201|Verrucomicrobia,37GBP@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	UDP binding domain	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
CH3_k127_12326801_6	481448.Minf_2089	6.539e-06	57.0	COG1729@1|root,COG1729@2|Bacteria,46ZG7@74201|Verrucomicrobia,37H0Y@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Tetratricopeptide repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
CH3_k127_12326801_2	478741.JAFS01000001_gene2106	1.766e-49	180.0	COG0498@1|root,COG0498@2|Bacteria,46TYU@74201|Verrucomicrobia,37G8J@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	E	Pyridoxal-phosphate dependent enzyme	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CH3_k127_12335929_1	309807.SRU_1452	7.033e-22	103.0	2DRV2@1|root,33D77@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_12335929_0	1173026.Glo7428_2698	8.264e-117	408.0	COG0745@1|root,COG4191@1|root,COG0745@2|Bacteria,COG4191@2|Bacteria,1G1PE@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
CH3_k127_12361677_23	1173026.Glo7428_3316	5.776e-61	218.0	COG0432@1|root,COG0432@2|Bacteria,1G61Z@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
CH3_k127_12361677_11	1123242.JH636434_gene3629	2.874e-118	391.0	COG2706@1|root,COG2706@2|Bacteria,2IY02@203682|Planctomycetes	203682|Planctomycetes	G	COG2706 3-carboxymuconate cyclase	-	-	3.1.1.31	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Lactonase
CH3_k127_12361677_26	290512.Paes_2385	1.099e-58	216.0	COG1262@1|root,COG1262@2|Bacteria,1FF87@1090|Chlorobi	1090|Chlorobi	O	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
CH3_k127_12361677_35	1415778.JQMM01000001_gene261	1.561e-41	162.0	COG2982@1|root,COG2982@2|Bacteria,1N0N6@1224|Proteobacteria,1SF4A@1236|Gammaproteobacteria,1JA7J@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Protein involved in outer membrane biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	AsmA
CH3_k127_12361677_50	335543.Sfum_2943	3.555e-13	75.0	COG0784@1|root,COG2202@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg,dCache_1
CH3_k127_12361677_42	497964.CfE428DRAFT_4931	1.318e-31	139.0	COG3330@1|root,COG3330@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4912)	-	-	-	ko:K09942	-	-	-	-	ko00000	-	-	-	DUF4912,Rho_N
CH3_k127_12361677_4	497964.CfE428DRAFT_2513	3.791e-189	604.0	COG1543@1|root,COG1543@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	2.4.1.18	ko:K03406,ko:K16149	ko00500,ko01100,ko01110,ko02020,ko02030,map00500,map01100,map01110,map02020,map02030	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko02035	-	GH57	-	DUF1957,Glyco_hydro_57,Glyco_transf_4,Glycos_transf_1
CH3_k127_12361677_33	324602.Caur_2619	2.004e-48	177.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CH3_k127_12361677_27	278957.ABEA03000094_gene4751	4.514e-54	192.0	COG4508@1|root,COG4508@2|Bacteria,46VH7@74201|Verrucomicrobia,3K7ZP@414999|Opitutae	414999|Opitutae	S	dUTPase	-	-	-	-	-	-	-	-	-	-	-	-	dUTPase_2
CH3_k127_12361677_31	278957.ABEA03000094_gene4754	3.835e-49	184.0	COG0811@1|root,COG0811@2|Bacteria,46SUA@74201|Verrucomicrobia,3K7EH@414999|Opitutae	414999|Opitutae	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
CH3_k127_12361677_55	543728.Vapar_0410	0.0001101	52.0	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,2VSMV@28216|Betaproteobacteria,4AEE0@80864|Comamonadaceae	28216|Betaproteobacteria	U	PFAM Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
CH3_k127_12361677_17	1123070.KB899248_gene182	1.309e-81	274.0	COG0377@1|root,COG0377@2|Bacteria,46SMM@74201|Verrucomicrobia,2ITJ6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
CH3_k127_12361677_21	1396418.BATQ01000167_gene1768	3.193e-65	228.0	COG0852@1|root,COG0852@2|Bacteria,46STM@74201|Verrucomicrobia,2IU60@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
CH3_k127_12361677_9	694431.DESACE_01260	4.204e-145	472.0	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,42M9G@68525|delta/epsilon subdivisions,2WIS7@28221|Deltaproteobacteria,2M6DK@213113|Desulfurellales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.6.5.3	ko:K00333,ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa,NiFeSe_Hases
CH3_k127_12361677_32	497964.CfE428DRAFT_0527	1.399e-48	178.0	COG1894@1|root,COG1894@2|Bacteria,46S8J@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Respiratory-chain NADH dehydrogenase domain 51 kDa subunit	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
CH3_k127_12361677_46	946077.W5A_01680	1.452e-15	87.0	2E35R@1|root,32Y5N@2|Bacteria,4P5KG@976|Bacteroidetes,1IAK3@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_12361677_3	497964.CfE428DRAFT_0527	2.505e-195	619.0	COG1894@1|root,COG1894@2|Bacteria,46S8J@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Respiratory-chain NADH dehydrogenase domain 51 kDa subunit	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
CH3_k127_12361677_47	1395587.P364_0100010	3.122e-15	78.0	COG0675@1|root,COG0675@2|Bacteria	2|Bacteria	L	Transposase, IS605 OrfB family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4178,HTH_OrfB_IS605
CH3_k127_12361677_5	497964.CfE428DRAFT_0528	4.283e-175	567.0	COG1034@1|root,COG3383@1|root,COG1034@2|Bacteria,COG3383@2|Bacteria,46S6S@74201|Verrucomicrobia	74201|Verrucomicrobia	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,NADH-G_4Fe-4S_3
CH3_k127_12361677_13	240016.ABIZ01000001_gene4776	3.603e-108	361.0	COG1005@1|root,COG1005@2|Bacteria,46SIJ@74201|Verrucomicrobia,2ITZ1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
CH3_k127_12361677_25	452637.Oter_0478	6.692e-60	212.0	COG1143@1|root,COG1143@2|Bacteria,46SNT@74201|Verrucomicrobia,3K7UR@414999|Opitutae	414999|Opitutae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
CH3_k127_12361677_38	1156937.MFUM_940009	3.833e-33	134.0	COG0839@1|root,COG0839@2|Bacteria,46T5P@74201|Verrucomicrobia,37GUV@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 6	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
CH3_k127_12361677_30	794903.OPIT5_18130	3.791e-49	179.0	COG0614@1|root,COG0614@2|Bacteria	2|Bacteria	P	abc-type fe3 -hydroxamate transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
CH3_k127_12361677_41	1156937.MFUM_940008	7.957e-32	128.0	COG0713@1|root,COG0713@2|Bacteria,46SX4@74201|Verrucomicrobia,37GV9@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
CH3_k127_12361677_6	1123070.KB899249_gene306	7.125e-163	533.0	COG1009@1|root,COG1009@2|Bacteria,46SDU@74201|Verrucomicrobia,2ITQ9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CP	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
CH3_k127_12361677_10	1156937.MFUM_940006	1.497e-125	419.0	COG1008@1|root,COG1008@2|Bacteria,46SE4@74201|Verrucomicrobia,37GAQ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	Proton-conducting membrane transporter	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
CH3_k127_12361677_15	485916.Dtox_1215	1.473e-101	350.0	COG1007@1|root,COG1007@2|Bacteria,1TR55@1239|Firmicutes,25ED8@186801|Clostridia,25ZY3@186807|Peptococcaceae	186801|Clostridia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
CH3_k127_12361677_36	478741.JAFS01000001_gene1519	1.806e-36	139.0	COG1141@1|root,COG1141@2|Bacteria,46T2D@74201|Verrucomicrobia,37GX8@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	4Fe-4S single cluster domain of Ferredoxin I	-	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13
CH3_k127_12361677_14	497964.CfE428DRAFT_2172	7.624e-103	351.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,46SRG@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Competence-damaged protein	cinA	-	3.5.1.42	ko:K03742	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
CH3_k127_12361677_49	1177154.Y5S_00007	8.499e-14	83.0	2FA92@1|root,342HR@2|Bacteria,1NYCG@1224|Proteobacteria,1SQ6S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_12361677_29	1121468.AUBR01000001_gene497	1.102e-52	194.0	COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,2498Z@186801|Clostridia,42EWM@68295|Thermoanaerobacterales	186801|Clostridia	L	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
CH3_k127_12361677_20	269084.syc1734_d	2.482e-71	252.0	COG1043@1|root,COG1043@2|Bacteria,1G3IU@1117|Cyanobacteria,1H2QC@1129|Synechococcus	1117|Cyanobacteria	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
CH3_k127_12361677_19	296591.Bpro_2193	6.196e-79	280.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,2VIFK@28216|Betaproteobacteria,4AB3M@80864|Comamonadaceae	28216|Betaproteobacteria	H	MoeA domain protein domain I and II	moeA1	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
CH3_k127_12361677_7	944480.ATUV01000001_gene1378	2.606e-160	523.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,2M6BJ@213113|Desulfurellales	28221|Deltaproteobacteria	NU	Type II secretion system protein E	pilB	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N,cNMP_binding
CH3_k127_12361677_8	595460.RRSWK_04461	1.298e-146	477.0	COG0673@1|root,COG0673@2|Bacteria,2IXRR@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CH3_k127_12361677_43	671143.DAMO_0994	5.382e-29	124.0	COG1247@1|root,COG1247@2|Bacteria	2|Bacteria	M	phosphinothricin N-acetyltransferase activity	MA20_16670	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CH3_k127_12361677_28	523841.HFX_0260	5.664e-53	200.0	COG0421@1|root,COG0477@1|root,arCOG00050@2157|Archaea,arCOG02682@2157|Archaea,2XUEJ@28890|Euryarchaeota,23T1E@183963|Halobacteria	183963|Halobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
CH3_k127_12361677_44	635013.TherJR_1799	1.891e-26	116.0	COG4262@1|root,COG4262@2|Bacteria,1UYRF@1239|Firmicutes,24AHS@186801|Clostridia	186801|Clostridia	S	Spermine/spermidine synthase domain	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
CH3_k127_12361677_0	1396141.BATP01000030_gene3783	2.038e-313	975.0	28I74@1|root,2Z8A0@2|Bacteria,46TG0@74201|Verrucomicrobia	74201|Verrucomicrobia	S	COG NOG26804 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_12361677_16	452637.Oter_2237	1.821e-101	340.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	f42a	-	-	-	-	-	-	-	-	-	-	-	Band_7
CH3_k127_12361677_51	452637.Oter_2236	6.586e-12	66.0	COG4877@1|root,COG4877@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Arc,RHH_5
CH3_k127_12361677_12	526224.Bmur_0878	1.257e-114	378.0	COG0616@1|root,COG0616@2|Bacteria,2J9E9@203691|Spirochaetes	203691|Spirochaetes	OU	Serine dehydrogenase proteinase	-	-	-	-	-	-	-	-	-	-	-	-	SDH_sah
CH3_k127_12361677_24	452637.Oter_0107	5.822e-61	222.0	COG2761@1|root,COG2761@2|Bacteria	2|Bacteria	Q	protein disulfide oxidoreductase activity	frnE	-	-	-	-	-	-	-	-	-	-	-	DSBA
CH3_k127_12361677_2	497964.CfE428DRAFT_6515	1.02e-296	973.0	COG0457@1|root,COG0457@2|Bacteria,46UKC@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	FAT,Peptidase_C39_2
CH3_k127_12361677_37	497964.CfE428DRAFT_2396	4.052e-34	134.0	COG0441@1|root,COG0441@2|Bacteria,46S5A@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
CH3_k127_12361677_48	1333856.L686_13365	2.883e-14	79.0	COG0515@1|root,COG0515@2|Bacteria,1NCFW@1224|Proteobacteria	1224|Proteobacteria	KLT	DKNYY family	-	-	-	-	-	-	-	-	-	-	-	-	DKNYY
CH3_k127_12361677_53	1321774.HMPREF9108_01413	2.048e-09	66.0	COG0515@1|root,COG0515@2|Bacteria,37AZU@32066|Fusobacteria	32066|Fusobacteria	KLT	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	DKNYY
CH3_k127_12361677_1	497964.CfE428DRAFT_2396	8.08e-297	924.0	COG0441@1|root,COG0441@2|Bacteria,46S5A@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
CH3_k127_12361677_34	331678.Cphamn1_2540	1.817e-42	158.0	2DNV7@1|root,32ZAW@2|Bacteria	2|Bacteria	S	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
CH3_k127_12361677_45	243090.RB10666	7.894e-21	109.0	COG1361@1|root,COG1361@2|Bacteria,2IYS8@203682|Planctomycetes	203682|Planctomycetes	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
CH3_k127_12361677_22	251221.35214774	2.3e-64	242.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	SBBP,TIG,VCBS
CH3_k127_12361677_40	1120953.AUBH01000005_gene2232	4.195e-32	129.0	COG3595@1|root,COG3595@2|Bacteria,1RFCY@1224|Proteobacteria,1S5RB@1236|Gammaproteobacteria,467PX@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
CH3_k127_12366264_1	452637.Oter_0123	6.01e-135	442.0	COG4122@1|root,COG4122@2|Bacteria	2|Bacteria	E	O-methyltransferase activity	safC	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Methyltransf_24,Methyltransf_3
CH3_k127_12366264_0	1349822.NSB1T_12810	8.54e-136	452.0	COG2189@1|root,COG2189@2|Bacteria,4NHTG@976|Bacteroidetes,2FQKU@200643|Bacteroidia,22YMU@171551|Porphyromonadaceae	976|Bacteroidetes	L	DNA methylase	-	-	2.1.1.72	ko:K00571,ko:K07319	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	MerR,N6_N4_Mtase
CH3_k127_12426125_2	234267.Acid_6003	9.515e-78	285.0	COG2251@1|root,COG3316@1|root,COG2251@2|Bacteria,COG3316@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cas_Cas4,DDE_Tnp_IS66,HHH_5,RNase_H_2
CH3_k127_12426125_8	118161.KB235918_gene5	9.142e-10	63.0	2DTC9@1|root,33JP3@2|Bacteria,1GB2W@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_12426125_0	237368.SCABRO_01787	2.307e-132	439.0	COG2963@1|root,COG3335@1|root,COG2963@2|Bacteria,COG3335@2|Bacteria	2|Bacteria	L	DDE superfamily endonuclease	-	-	-	ko:K07483,ko:K07497	-	-	-	-	ko00000	-	-	-	DDE_3,HTH_28,HTH_Tnp_1
CH3_k127_12426125_6	1173023.KE650771_gene588	1.074e-17	84.0	COG2442@1|root,COG2442@2|Bacteria,1G9FC@1117|Cyanobacteria,1JMBK@1189|Stigonemataceae	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
CH3_k127_12426125_7	1173263.Syn7502_01724	1.218e-10	66.0	COG4634@1|root,COG4634@2|Bacteria,1GA41@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_12426125_4	575540.Isop_1515	4.296e-45	176.0	COG1975@1|root,COG1975@2|Bacteria,2IXRN@203682|Planctomycetes	203682|Planctomycetes	O	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
CH3_k127_12426125_3	292563.Cyast_2134	1.998e-59	214.0	COG0642@1|root,COG2205@2|Bacteria,1G3D2@1117|Cyanobacteria	1117|Cyanobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c
CH3_k127_12426125_1	382464.ABSI01000010_gene3622	2.481e-103	353.0	COG0551@1|root,COG0551@2|Bacteria,46SJD@74201|Verrucomicrobia,2IVAK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Protein of unknown function (DUF1587)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt3,PSD2,PSD3,PSD4,PSD5
CH3_k127_12426679_5	671143.DAMO_0671	7.826e-14	74.0	COG0052@1|root,COG0052@2|Bacteria,2NP4M@2323|unclassified Bacteria	2|Bacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
CH3_k127_12426679_3	497964.CfE428DRAFT_2907	1.964e-89	302.0	COG0264@1|root,COG0264@2|Bacteria,46SUK@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
CH3_k127_12426679_0	497964.CfE428DRAFT_6681	2.711e-184	589.0	COG0535@1|root,COG0535@2|Bacteria,46V38@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF3463)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3463,Radical_SAM
CH3_k127_12426679_1	357804.Ping_3708	2.338e-116	389.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,1T1FT@1236|Gammaproteobacteria,2QJ8J@267894|Psychromonadaceae	1236|Gammaproteobacteria	V	MacB-like periplasmic core domain	VP1997	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CH3_k127_12426679_2	472759.Nhal_3356	1.252e-115	385.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,1T1FT@1236|Gammaproteobacteria,1WXP0@135613|Chromatiales	135613|Chromatiales	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CH3_k127_12426679_4	246197.MXAN_1805	4.968e-69	238.0	arCOG04954@1|root,2Z95Q@2|Bacteria,1R5K7@1224|Proteobacteria,431YS@68525|delta/epsilon subdivisions,2WX3C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_12442576_0	313606.M23134_00255	3.546e-71	267.0	COG3291@1|root,COG3291@2|Bacteria,4PKTY@976|Bacteroidetes,47RAA@768503|Cytophagia	976|Bacteroidetes	M	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	PKD,UnbV_ASPIC,VCBS
CH3_k127_12442576_1	452637.Oter_1999	1.114e-05	59.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5
CH3_k127_12442576_2	446470.Snas_4314	0.0005852	48.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE
CH3_k127_12451338_1	1396141.BATP01000003_gene4967	1.047e-96	332.0	COG3391@1|root,COG3391@2|Bacteria,46X7X@74201|Verrucomicrobia,2IUXV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	cytochrome C peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	CCP_MauG
CH3_k127_12451338_0	497964.CfE428DRAFT_1577	5.423e-157	504.0	COG0502@1|root,COG0502@2|Bacteria,46SFX@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Biotin and Thiamin Synthesis associated domain	-	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
CH3_k127_12451338_2	395493.BegalDRAFT_2935	7.043e-79	273.0	COG1408@1|root,COG1408@2|Bacteria,1RK37@1224|Proteobacteria,1SEEW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	hydrolase activity	yaeI	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2
CH3_k127_12464985_4	880070.Cycma_4229	1.356e-17	92.0	COG5337@1|root,COG5337@2|Bacteria,4NEH2@976|Bacteroidetes,47PGS@768503|Cytophagia	976|Bacteroidetes	M	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Fn3_assoc,LTD
CH3_k127_12464985_5	28072.Nos7524_4621	2.394e-12	76.0	COG0823@1|root,COG2304@1|root,COG3209@1|root,COG3210@1|root,COG0823@2|Bacteria,COG2304@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,1GQ0G@1117|Cyanobacteria,1HN8U@1161|Nostocales	1117|Cyanobacteria	MU	Dystroglycan-type cadherin-like domains.	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,He_PIG,RHS_repeat
CH3_k127_12464985_0	1396141.BATP01000040_gene2082	1.494e-212	713.0	COG2247@1|root,COG3291@1|root,COG4733@1|root,COG5492@1|root,COG2247@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria,COG5492@2|Bacteria,46TXW@74201|Verrucomicrobia	74201|Verrucomicrobia	M	cell wall binding repeat	-	-	-	-	-	-	-	-	-	-	-	-	PA14
CH3_k127_12464985_3	1396141.BATP01000060_gene4765	7.079e-28	133.0	COG0028@1|root,COG2730@1|root,COG2755@1|root,COG2931@1|root,COG3506@1|root,COG3637@1|root,COG4733@1|root,COG5184@1|root,COG0028@2|Bacteria,COG2730@2|Bacteria,COG2755@2|Bacteria,COG2931@2|Bacteria,COG3506@2|Bacteria,COG3637@2|Bacteria,COG4733@2|Bacteria,COG5184@2|Bacteria,46Z9Q@74201|Verrucomicrobia,2IVEQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	DEGMUZ	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta
CH3_k127_12464985_1	497964.CfE428DRAFT_2630	2.403e-162	525.0	COG1571@1|root,COG1571@2|Bacteria,46UI2@74201|Verrucomicrobia	74201|Verrucomicrobia	S	tRNA wobble cytosine modification	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_12464985_6	497964.CfE428DRAFT_2630	6.489e-08	60.0	COG1571@1|root,COG1571@2|Bacteria,46UI2@74201|Verrucomicrobia	74201|Verrucomicrobia	S	tRNA wobble cytosine modification	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_12464985_2	1403819.BATR01000162_gene5307	3.383e-132	427.0	COG4260@1|root,COG4260@2|Bacteria,46UVR@74201|Verrucomicrobia,2IV4M@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,HTH_17
CH3_k127_12476737_11	1396141.BATP01000003_gene5182	4.404e-31	126.0	COG0420@1|root,COG0420@2|Bacteria	2|Bacteria	L	3'-5' exonuclease activity	-	-	3.1.1.53	ko:K03547,ko:K05970	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Metallophos,Metallophos_2
CH3_k127_12476737_7	344747.PM8797T_03609	1.949e-53	197.0	COG0558@1|root,COG0558@2|Bacteria	2|Bacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.39	ko:K17884	-	-	R10464	RC00002,RC00078	ko00000,ko01000	-	-	-	CDP-OH_P_transf
CH3_k127_12476737_14	1095743.HMPREF1054_0309	2.833e-21	101.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,1RPI3@1236|Gammaproteobacteria,1Y8T2@135625|Pasteurellales	135625|Pasteurellales	S	Sel1-like repeats.	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
CH3_k127_12476737_2	452637.Oter_2821	4.126e-173	571.0	COG0755@1|root,COG0755@2|Bacteria,46SIH@74201|Verrucomicrobia,3K7UF@414999|Opitutae	414999|Opitutae	O	PFAM cytochrome c assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
CH3_k127_12476737_4	452637.Oter_2587	1.246e-100	340.0	COG1333@1|root,COG1333@2|Bacteria,46SUY@74201|Verrucomicrobia,3K75U@414999|Opitutae	414999|Opitutae	O	ResB-like family	-	-	-	-	-	-	-	-	-	-	-	-	ResB
CH3_k127_12476737_8	497964.CfE428DRAFT_1210	1.154e-51	198.0	2E533@1|root,32ZW9@2|Bacteria,46SZX@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_12476737_1	1156937.MFUM_810001	5.112e-189	602.0	COG1158@1|root,COG1158@2|Bacteria,46S5Y@74201|Verrucomicrobia,37G72@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
CH3_k127_12476737_0	1125863.JAFN01000001_gene34	1.143e-192	624.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,42M0T@68525|delta/epsilon subdivisions,2WJ3C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
CH3_k127_12476737_15	521045.Kole_0482	2.286e-19	102.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23,SH3_3
CH3_k127_12476737_9	485913.Krac_5135	1.195e-43	171.0	COG0483@1|root,COG0483@2|Bacteria,2G6JD@200795|Chloroflexi	200795|Chloroflexi	G	PFAM Inositol monophosphatase	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
CH3_k127_12476737_6	1028800.RG540_PA04370	1.649e-86	316.0	COG5652@1|root,COG5652@2|Bacteria,1MX6C@1224|Proteobacteria,2U18Q@28211|Alphaproteobacteria,4BBZB@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4962)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4962,Hepar_II_III
CH3_k127_12476737_10	1121924.ATWH01000017_gene3159	3.649e-32	145.0	COG3408@1|root,COG3408@2|Bacteria,2GYU2@201174|Actinobacteria,4FR4D@85023|Microbacteriaceae	201174|Actinobacteria	G	Glycosyl-hydrolase family 116, catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	DUF608
CH3_k127_12476737_16	497964.CfE428DRAFT_0107	1.584e-13	83.0	2CMJG@1|root,32SEZ@2|Bacteria,46T0G@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_12476737_17	1142394.PSMK_11740	8.163e-09	66.0	COG2165@1|root,COG2165@2|Bacteria,2IXWH@203682|Planctomycetes	203682|Planctomycetes	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CH3_k127_12476737_3	670307.HYPDE_33213	5.138e-154	509.0	COG3011@1|root,COG3011@2|Bacteria,1N0MB@1224|Proteobacteria	1224|Proteobacteria	S	Lipase maturation factor	-	-	-	-	-	-	-	-	-	-	-	-	DUF393,LMF1
CH3_k127_12476737_13	1173023.KE650771_gene1836	4.033e-24	113.0	COG1262@1|root,COG2944@1|root,COG1262@2|Bacteria,COG2944@2|Bacteria,1G0ZT@1117|Cyanobacteria	1117|Cyanobacteria	D	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,TIR_2
CH3_k127_12476737_12	706587.Desti_1336	9.709e-25	110.0	COG2771@1|root,COG2771@2|Bacteria,1NAK1@1224|Proteobacteria,42VEJ@68525|delta/epsilon subdivisions,2WS0Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Protein of unknown function (DUF4019)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4019
CH3_k127_12476737_5	452637.Oter_3479	2.242e-100	329.0	COG0129@1|root,COG0129@2|Bacteria,46UGZ@74201|Verrucomicrobia,3K7Q8@414999|Opitutae	414999|Opitutae	EG	Belongs to the IlvD Edd family	-	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
CH3_k127_12525970_11	762903.Pedsa_3064	2.579e-06	58.0	COG4409@1|root,COG4409@2|Bacteria,4NH3R@976|Bacteroidetes	976|Bacteroidetes	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2,CBM9_1
CH3_k127_12525970_0	1123248.KB893381_gene944	0.0	1086.0	COG1874@1|root,COG1874@2|Bacteria,4PPRG@976|Bacteroidetes	976|Bacteroidetes	G	Hypothetical glycosyl hydrolase 6	-	-	-	-	-	-	-	-	-	-	-	-	GHL6
CH3_k127_12525970_1	234267.Acid_7007	5e-324	1009.0	COG1649@1|root,COG1649@2|Bacteria	2|Bacteria	F	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	GHL10,GHL6,Glyco_hydro_42M,Polysacc_deac_1
CH3_k127_12525970_6	1210884.HG799468_gene13605	1.793e-91	340.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1,Polysacc_deac_1,Polysacc_deac_3
CH3_k127_12525970_9	452637.Oter_2210	3.247e-19	104.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	3.5.1.23	ko:K12349	ko00600,ko01100,ko04071,map00600,map01100,map04071	M00099	R01494	RC00064,RC00328	ko00000,ko00001,ko00002,ko01000	-	-	-	Ceramidase_alk,Ceramidse_alk_C
CH3_k127_12525970_5	314230.DSM3645_28727	1.048e-99	366.0	COG0613@1|root,COG0613@2|Bacteria,2IZFJ@203682|Planctomycetes	203682|Planctomycetes	S	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_12525970_2	1123277.KB893176_gene3715	1.121e-230	724.0	COG1649@1|root,COG1649@2|Bacteria	2|Bacteria	F	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	GHL10,SLH
CH3_k127_12525970_4	521674.Plim_1676	1.586e-101	341.0	COG0329@1|root,COG0329@2|Bacteria	2|Bacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
CH3_k127_12525970_3	1121904.ARBP01000013_gene349	1.078e-135	444.0	COG4948@1|root,COG4948@2|Bacteria,4NKNN@976|Bacteroidetes,47JKW@768503|Cytophagia	976|Bacteroidetes	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
CH3_k127_12525970_10	1540221.JQNI01000002_gene2916	3.26e-09	67.0	COG0491@1|root,COG0491@2|Bacteria,1WI41@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CH3_k127_12525970_7	555779.Dthio_PD1267	4.217e-60	220.0	COG0667@1|root,COG0667@2|Bacteria,1R77F@1224|Proteobacteria,42Y4Z@68525|delta/epsilon subdivisions,2WTTZ@28221|Deltaproteobacteria,2MCP4@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CH3_k127_12525970_12	1123277.KB893176_gene3707	4.529e-06	52.0	COG2173@1|root,COG2173@2|Bacteria	2|Bacteria	M	zinc D-Ala-D-Ala carboxypeptidase activity	-	-	3.4.13.22	ko:K08641	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	Peptidase_M15,SH3_3,SH3_4,VanY
CH3_k127_12525970_8	1545701.LACWKB10_1508	1.059e-20	108.0	2C38I@1|root,2ZA75@2|Bacteria,1V0KH@1239|Firmicutes,4HURI@91061|Bacilli,3F5H4@33958|Lactobacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_1262886_14	8364.ENSXETP00000010179	2.488e-10	74.0	2CMMP@1|root,2QQVA@2759|Eukaryota,38DQG@33154|Opisthokonta,3BC84@33208|Metazoa,3CVS6@33213|Bilateria,487IG@7711|Chordata,48ZK4@7742|Vertebrata	33208|Metazoa	S	F5/8 type C domain	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C
CH3_k127_1262886_13	1396141.BATP01000034_gene4198	5.751e-19	103.0	COG1409@1|root,COG2273@1|root,COG5337@1|root,COG1409@2|Bacteria,COG2273@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	3.2.1.73	ko:K01216,ko:K07004	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,CotH,DUF4971,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_43,HemolysinCabind,LTD,Laminin_G_3,Metallophos
CH3_k127_1262886_15	682795.AciX8_3725	4.321e-10	74.0	COG3250@1|root,COG3250@2|Bacteria,3Y3GV@57723|Acidobacteria,2JHVR@204432|Acidobacteriia	204432|Acidobacteriia	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4982,F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_64,Ig_3
CH3_k127_1262886_12	1396418.BATQ01000025_gene5257	9.757e-42	162.0	COG2940@1|root,COG2940@2|Bacteria,46W0B@74201|Verrucomicrobia,2IUGA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain	-	-	-	-	-	-	-	-	-	-	-	-	SET
CH3_k127_1262886_6	1535287.JP74_20325	2.979e-114	381.0	COG3876@1|root,COG3876@2|Bacteria,1MX3S@1224|Proteobacteria,2U1KM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
CH3_k127_1262886_4	886293.Sinac_6923	2.16e-126	408.0	COG2159@1|root,COG2159@2|Bacteria,2IZCY@203682|Planctomycetes	203682|Planctomycetes	S	metal-dependent hydrolase of the TIM-barrel fold	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
CH3_k127_1262886_8	886293.Sinac_6924	2.089e-87	299.0	COG2159@1|root,COG2159@2|Bacteria,2IZB9@203682|Planctomycetes	203682|Planctomycetes	S	metal-dependent hydrolase of the TIM-barrel fold	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
CH3_k127_1262886_11	697282.Mettu_1034	9.41e-45	169.0	COG0558@1|root,COG0558@2|Bacteria,1N35Q@1224|Proteobacteria,1T0Q8@1236|Gammaproteobacteria,1XFBQ@135618|Methylococcales	135618|Methylococcales	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	-	-	-	-	-	-	-	-	-	-	CDP-OH_P_transf
CH3_k127_1262886_9	517418.Ctha_0234	8.128e-52	191.0	COG1225@1|root,COG1225@2|Bacteria,1FF4E@1090|Chlorobi	1090|Chlorobi	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CH3_k127_1262886_10	644282.Deba_0317	4.901e-45	173.0	COG1102@1|root,COG1102@2|Bacteria,1R4GX@1224|Proteobacteria,42QKV@68525|delta/epsilon subdivisions,2WJS2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
CH3_k127_1262886_1	452637.Oter_0819	0.0	1292.0	COG0574@1|root,COG0574@2|Bacteria,46XFR@74201|Verrucomicrobia,3K763@414999|Opitutae	414999|Opitutae	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PPDK_N
CH3_k127_1262886_2	452637.Oter_0818	1.307e-252	786.0	COG0334@1|root,COG0334@2|Bacteria,46UBX@74201|Verrucomicrobia,3K7SK@414999|Opitutae	414999|Opitutae	E	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	-	R00248	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
CH3_k127_1262886_5	517418.Ctha_0233	9.327e-117	413.0	COG4232@1|root,COG4233@1|root,COG4232@2|Bacteria,COG4233@2|Bacteria,1FDRS@1090|Chlorobi	1090|Chlorobi	C	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
CH3_k127_1262886_3	1123508.JH636442_gene3931	1.206e-147	477.0	COG1506@1|root,COG1506@2|Bacteria,2IWTJ@203682|Planctomycetes	203682|Planctomycetes	E	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	AXE1
CH3_k127_1262886_7	240016.ABIZ01000001_gene4409	1.435e-102	341.0	COG3828@1|root,COG3828@2|Bacteria,46SV1@74201|Verrucomicrobia,2IV8Y@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
CH3_k127_1262886_0	448385.sce7733	0.0	1955.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,42NHZ@68525|delta/epsilon subdivisions,2WJ2H@28221|Deltaproteobacteria,2YX1T@29|Myxococcales	28221|Deltaproteobacteria	H	Methionine synthase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
CH3_k127_12635250_1	497964.CfE428DRAFT_0202	5.499e-69	240.0	COG0299@1|root,COG0299@2|Bacteria,46SS6@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
CH3_k127_12635250_6	661478.OP10G_4100	0.0002177	44.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	PT-HINT,RHS_repeat,VCBS
CH3_k127_12635250_5	696281.Desru_0074	1.038e-18	93.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,24HHW@186801|Clostridia,261Y7@186807|Peptococcaceae	186801|Clostridia	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
CH3_k127_12635250_3	497964.CfE428DRAFT_3693	2.295e-61	226.0	COG0616@1|root,COG0616@2|Bacteria,46SQ5@74201|Verrucomicrobia	74201|Verrucomicrobia	OU	signal peptide peptidase SppA, 36K type	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
CH3_k127_12635250_2	880073.Calab_1235	2.239e-61	225.0	COG0035@1|root,COG0035@2|Bacteria,2NP5M@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS11010	UPRTase
CH3_k127_12635250_0	1396141.BATP01000059_gene2466	1.5e-323	1012.0	COG0542@1|root,COG0542@2|Bacteria,46SD6@74201|Verrucomicrobia,2ITPB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	C-terminal, D2-small domain, of ClpB protein	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
CH3_k127_12635250_4	478741.JAFS01000002_gene742	9.168e-58	205.0	COG3869@1|root,COG3869@2|Bacteria,46S55@74201|Verrucomicrobia,37G4T@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	E	Catalyzes the specific phosphorylation of arginine residues in proteins	mcsB	-	2.7.14.1	ko:K19405	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	ATP-gua_Ptrans
CH3_k127_1263770_0	1254432.SCE1572_14255	1.257e-203	646.0	COG2978@1|root,COG2978@2|Bacteria,1MUJ1@1224|Proteobacteria,42N8Z@68525|delta/epsilon subdivisions,2WTR2@28221|Deltaproteobacteria,2YU56@29|Myxococcales	28221|Deltaproteobacteria	H	AbgT putative transporter family	abgT	-	-	ko:K12942	-	-	-	-	ko00000	-	-	-	ABG_transport
CH3_k127_1263770_4	234267.Acid_3218	9.451e-51	183.0	COG0824@1|root,COG0824@2|Bacteria	2|Bacteria	IQ	Thioesterase	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	Acyl-ACP_TE
CH3_k127_1263770_1	794903.OPIT5_11650	6.406e-138	452.0	COG2081@1|root,COG2081@2|Bacteria,46TWE@74201|Verrucomicrobia,3K7FU@414999|Opitutae	414999|Opitutae	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
CH3_k127_1263770_2	452637.Oter_1311	1.948e-76	264.0	COG2454@1|root,COG2454@2|Bacteria,46W2F@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF434)	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_1263770_5	886293.Sinac_3510	6.84e-43	171.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	DUF11,PKD
CH3_k127_1263770_3	1379698.RBG1_1C00001G0608	6.188e-70	254.0	COG0515@1|root,COG5616@1|root,COG0515@2|Bacteria,COG5616@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08282,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_16,TPR_2,TPR_8,TolB_N
CH3_k127_1263770_10	35754.JNYJ01000007_gene2850	0.0009629	53.0	COG3537@1|root,COG3537@2|Bacteria,2GKYM@201174|Actinobacteria,4DAT5@85008|Micromonosporales	201174|Actinobacteria	G	Glycosyl hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_92
CH3_k127_1263770_8	479432.Sros_0936	8.238e-11	76.0	COG3188@1|root,COG3188@2|Bacteria,2HQZC@201174|Actinobacteria,4EFZ0@85012|Streptosporangiales	201174|Actinobacteria	NU	Glycosyl hydrolase family 48	cbhB	-	-	-	-	-	-	-	-	-	-	-	CBM_2,Glyco_hydro_48
CH3_k127_1263770_9	1195236.CTER_5216	8.053e-05	56.0	COG1572@1|root,COG3209@1|root,COG3210@1|root,COG4932@1|root,COG1572@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,COG4932@2|Bacteria,1TR9M@1239|Firmicutes,24BEI@186801|Clostridia,3WMNE@541000|Ruminococcaceae	186801|Clostridia	MU	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	SLH
CH3_k127_1263770_7	309800.C498_02055	5.238e-15	90.0	arCOG05978@1|root,arCOG05978@2157|Archaea,2XU7Y@28890|Euryarchaeota,23SST@183963|Halobacteria	183963|Halobacteria	S	Fibronectin type III domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_1320373_8	497964.CfE428DRAFT_5353	0.0005346	44.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,HATPase_c,HD_5,Response_reg,T2SSE_N
CH3_k127_1320373_2	1382315.JPOI01000001_gene1963	3.825e-71	253.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,4HABP@91061|Bacilli,1WE42@129337|Geobacillus	91061|Bacilli	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1,2.4.2.28	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	M00034	R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
CH3_k127_1320373_7	880073.Calab_0824	6.553e-29	123.0	COG0295@1|root,COG0295@2|Bacteria,2NPJN@2323|unclassified Bacteria	2|Bacteria	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	GO:0001882,GO:0001884,GO:0003674,GO:0003824,GO:0004126,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006216,GO:0006217,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008655,GO:0009056,GO:0009058,GO:0009116,GO:0009119,GO:0009120,GO:0009164,GO:0009972,GO:0009987,GO:0015949,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0036094,GO:0042454,GO:0042802,GO:0043094,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046087,GO:0046092,GO:0046121,GO:0046125,GO:0046127,GO:0046131,GO:0046133,GO:0046135,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0047844,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0097159,GO:0097367,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	iECO103_1326.ECO103_2618	dCMP_cyt_deam_1,dCMP_cyt_deam_2
CH3_k127_1320373_5	335543.Sfum_2639	2.015e-59	227.0	COG0784@1|root,COG2203@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MFW@68525|delta/epsilon subdivisions,2WKMP@28221|Deltaproteobacteria,2MQVW@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9,Response_reg
CH3_k127_1320373_1	278957.ABEA03000085_gene2554	1.052e-108	359.0	COG0583@1|root,COG0583@2|Bacteria,46SCJ@74201|Verrucomicrobia,3K7FY@414999|Opitutae	414999|Opitutae	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CH3_k127_1320373_6	481448.Minf_1524	2.122e-34	141.0	COG0452@1|root,COG0452@2|Bacteria,46WUX@74201|Verrucomicrobia,37GRH@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	H	DNA / pantothenate metabolism flavoprotein	-	-	6.3.2.5	ko:K21977	ko00770,map00770	M00120	R04231	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP
CH3_k127_1320373_3	452637.Oter_0619	1.482e-66	239.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	VVA1313	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CH3_k127_1320373_0	497964.CfE428DRAFT_3481	9.365e-209	673.0	COG0443@1|root,COG0443@2|Bacteria,46TYN@74201|Verrucomicrobia	74201|Verrucomicrobia	O	MreB/Mbl protein	-	-	-	-	-	-	-	-	-	-	-	-	HSP70
CH3_k127_1320373_4	647113.Metok_0016	3.768e-64	236.0	COG0668@1|root,arCOG01568@2157|Archaea,2XSU5@28890|Euryarchaeota,23QB0@183939|Methanococci	183939|Methanococci	M	PFAM MscS Mechanosensitive ion channel	-	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
CH3_k127_1320799_0	481448.Minf_1705	1.778e-132	439.0	COG0265@1|root,COG0265@2|Bacteria,46SHP@74201|Verrucomicrobia,37G39@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	O	Trypsin-like serine protease	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
CH3_k127_1320799_1	929562.Emtol_1205	1.386e-111	366.0	COG1028@1|root,COG1028@2|Bacteria,4NJKA@976|Bacteroidetes,47KN3@768503|Cytophagia	976|Bacteroidetes	IQ	Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CH3_k127_1320799_6	234267.Acid_0995	4.906e-14	84.0	COG3391@1|root,COG3391@2|Bacteria,3Y7I2@57723|Acidobacteria	57723|Acidobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_1320799_2	1303518.CCALI_02909	4.88e-106	357.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	ytaP	-	-	-	-	-	-	-	-	-	-	-	AXE1,Abhydrolase_7,DLH,Peptidase_S15,Peptidase_S9
CH3_k127_1320799_4	649639.Bcell_1282	2.796e-28	120.0	2E58T@1|root,33017@2|Bacteria,1VARJ@1239|Firmicutes,4HKU9@91061|Bacilli,1ZHPC@1386|Bacillus	91061|Bacilli	S	Uncharacterised protein family (UPF0158)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0158
CH3_k127_1320799_3	1396141.BATP01000025_gene931	8.842e-77	271.0	COG0053@1|root,COG0053@2|Bacteria,46SPJ@74201|Verrucomicrobia,2IUZU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Dimerisation domain of Zinc Transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
CH3_k127_1320799_5	1042209.HK44_027725	2.055e-15	78.0	COG0732@1|root,COG0732@2|Bacteria,1MXVH@1224|Proteobacteria,1S29W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	COG0732 Restriction endonuclease S subunits	hsdS	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
CH3_k127_1320799_8	1078085.HMPREF1210_01122	3.4e-05	54.0	2DDVZ@1|root,2ZJI2@2|Bacteria,1W5EF@1239|Firmicutes,4I14U@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_1320799_7	180281.CPCC7001_1993	2.53e-13	72.0	COG0732@1|root,COG0732@2|Bacteria,1G6EU@1117|Cyanobacteria,22TSW@167375|Cyanobium	1117|Cyanobacteria	L	Type I restriction modification DNA specificity domain	-	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
CH3_k127_13337_1	192952.MM_3198	1.743e-75	259.0	COG1073@1|root,arCOG01661@2157|Archaea,2XVIC@28890|Euryarchaeota,2NANZ@224756|Methanomicrobia	224756|Methanomicrobia	S	Alpha/beta hydrolase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Peptidase_S9
CH3_k127_13337_0	1123242.JH636434_gene5340	1.498e-111	385.0	COG1413@1|root,COG1413@2|Bacteria,2IZE1@203682|Planctomycetes	203682|Planctomycetes	C	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
CH3_k127_1346762_0	471854.Dfer_1900	4.664e-28	130.0	COG4409@1|root,COG4409@2|Bacteria,4P66K@976|Bacteroidetes	976|Bacteroidetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
CH3_k127_1346762_1	1254432.SCE1572_31120	3.249e-22	106.0	COG2020@1|root,COG2020@2|Bacteria,1QTC1@1224|Proteobacteria,437VD@68525|delta/epsilon subdivisions,2X34Z@28221|Deltaproteobacteria,2Z1RR@29|Myxococcales	28221|Deltaproteobacteria	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
CH3_k127_1390723_0	497964.CfE428DRAFT_5970	6.063e-256	801.0	COG1217@1|root,COG1217@2|Bacteria,46SHA@74201|Verrucomicrobia	74201|Verrucomicrobia	T	elongation factor Tu domain 2 protein	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
CH3_k127_1390723_3	1499967.BAYZ01000119_gene3208	6.838e-20	102.0	COG0859@1|root,COG0859@2|Bacteria,2NP5P@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferase, family 9	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
CH3_k127_1390723_2	1396418.BATQ01000166_gene1881	1.081e-46	173.0	COG0299@1|root,COG0615@1|root,COG0299@2|Bacteria,COG0615@2|Bacteria,46SUW@74201|Verrucomicrobia,2IWN8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	FIM	Cytidylyltransferase-like	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like,Formyl_trans_N
CH3_k127_1390723_1	646529.Desaci_3169	4.166e-48	185.0	COG0500@1|root,COG2226@2|Bacteria,1TQEA@1239|Firmicutes,2495M@186801|Clostridia,260GE@186807|Peptococcaceae	186801|Clostridia	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
CH3_k127_1390723_4	926569.ANT_12920	1.566e-16	87.0	COG0455@1|root,COG0745@1|root,COG0455@2|Bacteria,COG0745@2|Bacteria,2G8KV@200795|Chloroflexi	200795|Chloroflexi	KT	AAA domain	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Response_reg
CH3_k127_1390723_5	247490.KSU1_C1333	6.631e-14	82.0	COG4968@1|root,COG4968@2|Bacteria,2J519@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CH3_k127_1460338_2	479435.Kfla_4525	4.248e-109	366.0	COG1957@1|root,COG1957@2|Bacteria	2|Bacteria	F	ribosylpyrimidine nucleosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF547
CH3_k127_1460338_3	886293.Sinac_7535	2.287e-107	362.0	COG5434@1|root,COG5434@2|Bacteria,2IX4K@203682|Planctomycetes	2|Bacteria	M	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Pectate_lyase_3
CH3_k127_1460338_0	1122931.AUAE01000028_gene113	7.465e-275	876.0	2CB8C@1|root,33T5I@2|Bacteria,4P0N1@976|Bacteroidetes,2FX4B@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_1460338_1	452637.Oter_2972	1.131e-214	677.0	COG3669@1|root,COG3669@2|Bacteria,46Y1K@74201|Verrucomicrobia,3K8SP@414999|Opitutae	414999|Opitutae	G	PFAM glycoside hydrolase family 29	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos
CH3_k127_1460338_7	1210884.HG799480_gene15519	4.175e-26	116.0	COG1387@1|root,COG1387@2|Bacteria,2IZ7D@203682|Planctomycetes	203682|Planctomycetes	E	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CH3_k127_1460338_6	1303518.CCALI_02246	7.374e-55	215.0	COG2730@1|root,COG2730@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_6,CHB_HEX_C_1,Cellulase,F5_F8_type_C
CH3_k127_1460338_5	1396141.BATP01000002_gene4845	2.762e-58	213.0	COG2197@1|root,COG2197@2|Bacteria,46TQM@74201|Verrucomicrobia,2IVME@203494|Verrucomicrobiae	2|Bacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CH3_k127_1460338_4	1396141.BATP01000002_gene4846	5.78e-85	302.0	COG4585@1|root,COG4585@2|Bacteria,46UGH@74201|Verrucomicrobia,2IVFF@203494|Verrucomicrobiae	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_2,HisKA_3
CH3_k127_1481040_3	1280390.CBQR020000048_gene957	1.457e-53	199.0	COG5184@1|root,COG5184@2|Bacteria,1UZD4@1239|Firmicutes,4HD48@91061|Bacilli,26VBQ@186822|Paenibacillaceae	91061|Bacilli	DZ	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin-like,RCC1_2,SLH
CH3_k127_1481040_0	497964.CfE428DRAFT_0079	1.359e-174	558.0	COG0277@1|root,COG0277@2|Bacteria,46SFA@74201|Verrucomicrobia	74201|Verrucomicrobia	C	FAD linked oxidases, C-terminal domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
CH3_k127_1481040_6	1300345.LF41_2927	0.0001663	49.0	2DSC2@1|root,33FFW@2|Bacteria,1QJUP@1224|Proteobacteria,1THW7@1236|Gammaproteobacteria,1X8XP@135614|Xanthomonadales	135614|Xanthomonadales	S	Putative prokaryotic signal transducing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2007
CH3_k127_1481040_2	452637.Oter_2116	4.421e-78	273.0	COG4956@1|root,COG4956@2|Bacteria,46TFJ@74201|Verrucomicrobia,3K8ZF@414999|Opitutae	414999|Opitutae	S	SMART Nucleotide binding protein PINc	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_1481040_5	525146.Ddes_0534	2.336e-06	59.0	COG1463@1|root,COG1463@2|Bacteria,1NCUG@1224|Proteobacteria,42SCT@68525|delta/epsilon subdivisions,2WPA7@28221|Deltaproteobacteria,2MC24@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	PFAM Mammalian cell entry related domain protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
CH3_k127_1481040_1	644282.Deba_0203	6.165e-84	286.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,42NI4@68525|delta/epsilon subdivisions,2WKRT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
CH3_k127_1481040_4	240016.ABIZ01000001_gene5316	2.014e-53	193.0	COG0767@1|root,COG0767@2|Bacteria,46SXR@74201|Verrucomicrobia,2ITY5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	Q	Permease MlaE	-	-	-	-	-	-	-	-	-	-	-	-	MlaE
CH3_k127_1502071_5	886293.Sinac_6493	4.496e-96	330.0	COG0501@1|root,COG0501@2|Bacteria,2IYND@203682|Planctomycetes	203682|Planctomycetes	O	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
CH3_k127_1502071_8	1396141.BATP01000024_gene851	6.181e-19	90.0	2EM29@1|root,33ERR@2|Bacteria,46WJK@74201|Verrucomicrobia,2IWEX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_1502071_9	913325.N799_06220	3.245e-12	79.0	COG1538@1|root,COG1538@2|Bacteria,1PCPQ@1224|Proteobacteria,1RRRP@1236|Gammaproteobacteria,1X406@135614|Xanthomonadales	135614|Xanthomonadales	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
CH3_k127_1502071_1	1396141.BATP01000024_gene848	8.779e-166	539.0	COG0845@1|root,COG0845@2|Bacteria,46SVD@74201|Verrucomicrobia,2IUGZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Protein of unknown function (DUF3347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3347,HlyD_D23
CH3_k127_1502071_0	1396141.BATP01000024_gene849	0.0	1744.0	COG3696@1|root,COG3696@2|Bacteria,46SJ1@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	cusA	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
CH3_k127_1502071_6	1403819.BATR01000123_gene4356	8.563e-33	139.0	28KDQ@1|root,2ZA05@2|Bacteria,46VJS@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_1502071_10	376686.Fjoh_2192	1.488e-09	67.0	COG2010@1|root,COG2010@2|Bacteria,4NXZT@976|Bacteroidetes,1I673@117743|Flavobacteriia,2NX4B@237|Flavobacterium	976|Bacteroidetes	C	Dihaem cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DHC
CH3_k127_1502071_3	926550.CLDAP_13850	1.44e-129	424.0	COG0075@1|root,COG0075@2|Bacteria,2G5P3@200795|Chloroflexi	2|Bacteria	E	PFAM aminotransferase class V	phnW	GO:0003674,GO:0003824	2.5.1.49,2.6.1.37,3.11.1.1	ko:K01740,ko:K03430,ko:K05306	ko00270,ko00440,ko01100,ko01120,map00270,map00440,map01100,map01120	-	R00747,R01287,R04152,R04859	RC00008,RC00020,RC00062,RC00368,RC02821,RC02848	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_5
CH3_k127_1502071_2	1122135.KB893134_gene3491	3.472e-131	432.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,2TT6G@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CH3_k127_1502071_4	6500.XP_005099940.1	2.037e-116	381.0	COG0637@1|root,2QU58@2759|Eukaryota,39WII@33154|Opisthokonta,3BF9K@33208|Metazoa,3D4RC@33213|Bilateria	33208|Metazoa	S	Haloacid dehalogenase-like hydrolase	-	-	3.11.1.1	ko:K05306	ko00440,ko01100,ko01120,map00440,map01100,map01120	-	R00747	RC00368	ko00000,ko00001,ko01000	-	-	-	HAD_2
CH3_k127_1502071_7	44056.XP_009033642.1	3.118e-19	89.0	COG0160@1|root,KOG1403@2759|Eukaryota	2759|Eukaryota	E	ethanolamine-phosphate phospho-lyase activity	-	-	4.2.3.2	ko:K14286	ko00564,ko01100,map00564,map01100	-	R00748	RC00369	ko00000,ko00001,ko01000	-	-	-	Aminotran_3,Peptidase_M23
CH3_k127_1525062_5	686340.Metal_0565	4.953e-53	210.0	COG1002@1|root,COG1943@1|root,COG2890@1|root,COG1002@2|Bacteria,COG1943@2|Bacteria,COG2890@2|Bacteria,1RIWM@1224|Proteobacteria,1S7RK@1236|Gammaproteobacteria,1XFWD@135618|Methylococcales	135618|Methylococcales	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
CH3_k127_1525062_6	706587.Desti_1189	1.619e-52	208.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,42MGP@68525|delta/epsilon subdivisions,2WIZ2@28221|Deltaproteobacteria,2MQUW@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
CH3_k127_1525062_4	530564.Psta_0173	5.509e-95	328.0	COG0501@1|root,COG3170@1|root,COG0501@2|Bacteria,COG3170@2|Bacteria,2IXM0@203682|Planctomycetes	203682|Planctomycetes	O	Zn-dependent protease with chaperone function	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
CH3_k127_1525062_0	497964.CfE428DRAFT_0141	0.0	1075.0	COG1082@1|root,COG4993@1|root,COG1082@2|Bacteria,COG4993@2|Bacteria,46T43@74201|Verrucomicrobia	74201|Verrucomicrobia	G	PFAM Pyrrolo-quinoline quinone	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	Cytochrome_CBB3,PQQ
CH3_k127_1525062_1	1396418.BATQ01000117_gene4568	2.169e-231	727.0	COG0738@1|root,COG0738@2|Bacteria,46U7F@74201|Verrucomicrobia,2IUMJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CH3_k127_1525062_2	497964.CfE428DRAFT_5737	2.133e-199	628.0	COG0673@1|root,COG0673@2|Bacteria,46UQI@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CH3_k127_1525062_10	1123242.JH636435_gene2068	1.813e-12	80.0	COG1413@1|root,COG1413@2|Bacteria,2J011@203682|Planctomycetes	203682|Planctomycetes	C	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
CH3_k127_1525062_3	935948.KE386494_gene695	9.37e-147	489.0	COG1874@1|root,COG1874@2|Bacteria,1TQN6@1239|Firmicutes,2488V@186801|Clostridia,42FYE@68295|Thermoanaerobacterales	186801|Clostridia	G	PFAM Glycoside hydrolase family 42 domain protein	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
CH3_k127_1525062_11	1273125.Rrhod_2956	0.0003437	49.0	COG5512@1|root,COG5512@2|Bacteria,2GNQ4@201174|Actinobacteria,4FUXM@85025|Nocardiaceae	201174|Actinobacteria	S	Belongs to the UPF0232 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
CH3_k127_1525062_8	471223.GWCH70_1512	3.284e-21	100.0	COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,4H9KR@91061|Bacilli,1WEX0@129337|Geobacillus	91061|Bacilli	G	PTS system, Lactose/Cellobiose specific IIB subunit	fruA	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563	2.7.1.202	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
CH3_k127_1525062_9	1123248.KB893324_gene1755	6.049e-15	87.0	COG0745@1|root,COG0745@2|Bacteria,4NG7D@976|Bacteroidetes,1IPM8@117747|Sphingobacteriia	976|Bacteroidetes	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoP	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CH3_k127_1525062_7	497964.CfE428DRAFT_5353	9.306e-27	124.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,HATPase_c,HD_5,Response_reg,T2SSE_N
CH3_k127_1532730_1	478741.JAFS01000002_gene596	2.21e-83	284.0	COG4992@1|root,COG4992@2|Bacteria,46SUV@74201|Verrucomicrobia,37G7B@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	E	Aminotransferase class-III	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CH3_k127_1532730_0	497964.CfE428DRAFT_5386	1.46e-128	420.0	COG2876@1|root,COG2876@2|Bacteria,46SUJ@74201|Verrucomicrobia	74201|Verrucomicrobia	E	PFAM DAHP synthetase I KDSA	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
CH3_k127_1532730_2	497964.CfE428DRAFT_0260	1.448e-56	201.0	COG0822@1|root,COG0822@2|Bacteria,46VAC@74201|Verrucomicrobia	74201|Verrucomicrobia	C	NifU-like N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	NifU_N
CH3_k127_1532730_3	497964.CfE428DRAFT_0261	3.578e-42	158.0	COG0607@1|root,COG0607@2|Bacteria,46VE6@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CH3_k127_1557202_3	661478.OP10G_4327	3.415e-150	487.0	COG2730@1|root,COG2730@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase,DUF4038,DUF5060,F5_F8_type_C,Glyco_hydro_81
CH3_k127_1557202_2	1403819.BATR01000027_gene886	8.712e-190	599.0	COG3345@1|root,COG3345@2|Bacteria,46XA8@74201|Verrucomicrobia,2IV69@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Carbohydrate esterase, sialic acid-specific acetylesterase	-	-	-	-	-	-	-	-	-	-	-	-	SASA
CH3_k127_1557202_0	497964.CfE428DRAFT_0038	3.329e-283	884.0	28MCY@1|root,2ZAQW@2|Bacteria,46TDW@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_1557202_1	497964.CfE428DRAFT_1769	1.166e-264	823.0	28MCY@1|root,2ZAQW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_1573819_4	1396141.BATP01000032_gene4314	1.141e-91	314.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CH3_k127_1573819_12	349521.HCH_00950	2.466e-23	109.0	COG2339@1|root,COG2339@2|Bacteria	2|Bacteria	D	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
CH3_k127_1573819_13	324602.Caur_3413	2.115e-14	87.0	COG0497@1|root,COG1196@1|root,COG0497@2|Bacteria,COG1196@2|Bacteria,2GA8M@200795|Chloroflexi,37598@32061|Chloroflexia	32061|Chloroflexia	DL	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_1573819_2	886293.Sinac_2616	3.195e-133	432.0	COG0714@1|root,COG0714@2|Bacteria,2IY1M@203682|Planctomycetes	203682|Planctomycetes	S	ATPase associated with	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CH3_k127_1573819_1	1121440.AUMA01000005_gene2707	3.151e-135	440.0	COG2957@1|root,COG2957@2|Bacteria,1MX65@1224|Proteobacteria,42NAS@68525|delta/epsilon subdivisions,2WNAF@28221|Deltaproteobacteria,2M9I9@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Belongs to the agmatine deiminase family	aguA	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
CH3_k127_1573819_8	177437.HRM2_24220	4.509e-55	200.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42Q40@68525|delta/epsilon subdivisions,2WKJ7@28221|Deltaproteobacteria,2MK6F@213118|Desulfobacterales	28221|Deltaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CH3_k127_1573819_6	378806.STAUR_4743	1.943e-72	253.0	COG1028@1|root,COG1028@2|Bacteria,1MU2T@1224|Proteobacteria,43A1N@68525|delta/epsilon subdivisions,2X25S@28221|Deltaproteobacteria,2YYJ4@29|Myxococcales	28221|Deltaproteobacteria	IQ	NAD dependent epimerase dehydratase family protein	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CH3_k127_1573819_5	641524.ADICYQ_0788	4.548e-76	267.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CH3_k127_1573819_7	234267.Acid_2129	7.213e-68	241.0	COG0693@1|root,COG0693@2|Bacteria,3Y3JB@57723|Acidobacteria	57723|Acidobacteria	S	DJ-1/PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
CH3_k127_1573819_3	1123399.AQVE01000001_gene684	8.175e-106	381.0	COG3291@1|root,COG5295@1|root,COG3291@2|Bacteria,COG5295@2|Bacteria,1RGWM@1224|Proteobacteria,1SKIX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	UW	Metallo-peptidase family M12B Reprolysin-like	-	-	-	-	-	-	-	-	-	-	-	-	Reprolysin_3
CH3_k127_1573819_10	497964.CfE428DRAFT_5098	2.143e-29	138.0	COG1075@1|root,COG1404@1|root,COG3055@1|root,COG3391@1|root,COG1075@2|Bacteria,COG1404@2|Bacteria,COG3055@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	1.1.3.6,3.2.1.4	ko:K01179,ko:K03333,ko:K12287	ko00500,ko00984,ko01100,ko01120,map00500,map00984,map01100,map01120	-	R01459,R06200,R11307,R11308	RC00146	ko00000,ko00001,ko01000,ko02044	-	GH5,GH9	-	Kelch_1,Laminin_G_3,Malectin
CH3_k127_1573819_14	497964.CfE428DRAFT_4431	1.517e-11	79.0	COG1361@1|root,COG1520@1|root,COG1572@1|root,COG3227@1|root,COG1361@2|Bacteria,COG1520@2|Bacteria,COG1572@2|Bacteria,COG3227@2|Bacteria	2|Bacteria	E	Zinc metalloprotease (Elastase)	-	-	-	ko:K20274	ko02024,map02024	-	-	-	ko00000,ko00001,ko01002	-	-	-	CHU_C,FTP,PQQ_2,Peptidase_M36
CH3_k127_1573819_15	246194.CHY_0024	2.089e-11	68.0	COG0432@1|root,COG0432@2|Bacteria,1V201@1239|Firmicutes,24FTY@186801|Clostridia,42G53@68295|Thermoanaerobacterales	186801|Clostridia	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
CH3_k127_1573819_17	1123073.KB899242_gene1643	2.501e-05	57.0	COG1520@1|root,COG5571@1|root,COG1520@2|Bacteria,COG5571@2|Bacteria	2|Bacteria	N	outer membrane autotransporter	yhjY	-	-	ko:K12287,ko:K12686	-	-	-	-	ko00000,ko02000,ko02044	1.B.12.8	-	-	Autotransporter,DUF4421,Lipase_GDSL
CH3_k127_1573819_11	760192.Halhy_1640	2.026e-25	112.0	COG0693@1|root,COG0693@2|Bacteria,4NQI1@976|Bacteroidetes,1IQJB@117747|Sphingobacteriia	976|Bacteroidetes	S	Intracellular protease, PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
CH3_k127_1573819_9	382464.ABSI01000011_gene2968	7.793e-53	210.0	COG0515@1|root,COG0515@2|Bacteria	382464.ABSI01000011_gene2968|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_1573819_16	1189620.AJXL01000074_gene3244	3.324e-09	68.0	COG1345@1|root,COG1361@1|root,COG1520@1|root,COG3291@1|root,COG1345@2|Bacteria,COG1361@2|Bacteria,COG1520@2|Bacteria,COG3291@2|Bacteria,4NEZF@976|Bacteroidetes,1HZ6F@117743|Flavobacteriia,2NSYB@237|Flavobacterium	976|Bacteroidetes	N	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_1573819_0	1396141.BATP01000060_gene4727	1.384e-221	732.0	COG0457@1|root,COG3712@1|root,COG0457@2|Bacteria,COG3712@2|Bacteria	2|Bacteria	PT	iron ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	FecR,TPR_16,TPR_19,TPR_8,TonB_dep_Rec
CH3_k127_1573819_18	268407.PWYN_09035	0.000334	50.0	COG3666@1|root,COG3666@2|Bacteria,1TQQ9@1239|Firmicutes,4H9KK@91061|Bacilli,26U3R@186822|Paenibacillaceae	91061|Bacilli	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
CH3_k127_1574086_3	794903.OPIT5_23905	5.616e-10	67.0	COG2165@1|root,COG2165@2|Bacteria,46Z9G@74201|Verrucomicrobia,3K9NR@414999|Opitutae	2|Bacteria	U	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
CH3_k127_1574086_0	452637.Oter_0693	1.222e-172	548.0	COG0019@1|root,COG0019@2|Bacteria,46WJD@74201|Verrucomicrobia	74201|Verrucomicrobia	E	PFAM Orn DAP Arg decarboxylase 2	-	-	4.1.1.17	ko:K01581	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	M00134	R00670	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
CH3_k127_1574086_1	794903.OPIT5_23665	6.384e-78	267.0	COG0730@1|root,COG0730@2|Bacteria,46V74@74201|Verrucomicrobia,3K8YW@414999|Opitutae	414999|Opitutae	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
CH3_k127_1574086_2	1127673.GLIP_1568	3.554e-38	154.0	COG3832@1|root,COG3832@2|Bacteria,1RDGX@1224|Proteobacteria,1S4FQ@1236|Gammaproteobacteria,4675R@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
CH3_k127_1631746_3	1123242.JH636436_gene318	7.345e-77	279.0	COG0176@1|root,COG0176@2|Bacteria,2IYC8@203682|Planctomycetes	203682|Planctomycetes	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	-	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
CH3_k127_1631746_2	575540.Isop_3679	4.507e-122	413.0	COG3119@1|root,COG3119@2|Bacteria,2IYH5@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	3.1.6.4	ko:K01132	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00077,M00079	R07806	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Sulfatase
CH3_k127_1631746_1	1123242.JH636434_gene5489	1.518e-139	458.0	COG1070@1|root,COG1070@2|Bacteria,2IXYW@203682|Planctomycetes	203682|Planctomycetes	G	COG1070 Sugar (pentulose and hexulose)	-	-	2.7.1.5	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01902,R03014	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
CH3_k127_1631746_6	1297865.APJD01000005_gene3689	8.097e-07	60.0	2BPPV@1|root,32IH2@2|Bacteria,1NFYU@1224|Proteobacteria,2UIKJ@28211|Alphaproteobacteria,3K4IG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_1631746_5	383372.Rcas_1314	5.438e-20	91.0	2BRHQ@1|root,32KGQ@2|Bacteria,2GB33@200795|Chloroflexi,377U1@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_1631746_4	1499967.BAYZ01000119_gene3173	3.016e-53	195.0	28JE3@1|root,2Z98B@2|Bacteria,2NQ8M@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
CH3_k127_1631746_0	497964.CfE428DRAFT_3901	1.038e-150	488.0	COG0210@1|root,COG0210@2|Bacteria,46S8H@74201|Verrucomicrobia	74201|Verrucomicrobia	L	PFAM UvrD REP helicase	uvrD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
CH3_k127_165724_0	278957.ABEA03000202_gene4301	1.48e-260	809.0	COG0187@1|root,COG0187@2|Bacteria,46TW5@74201|Verrucomicrobia,3K7GR@414999|Opitutae	414999|Opitutae	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
CH3_k127_165724_12	1142394.PSMK_14730	7.353e-56	207.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
CH3_k127_165724_6	497964.CfE428DRAFT_4175	8.438e-87	296.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CH3_k127_165724_16	1403819.BATR01000069_gene2089	2.035e-29	125.0	COG4968@1|root,COG4968@2|Bacteria,46VT8@74201|Verrucomicrobia,2IW29@203494|Verrucomicrobiae	203494|Verrucomicrobiae	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
CH3_k127_165724_21	794903.OPIT5_29655	4.501e-10	71.0	COG4968@1|root,COG4968@2|Bacteria	794903.OPIT5_29655|-	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_165724_18	497964.CfE428DRAFT_4171	3.29e-20	98.0	2ETM2@1|root,33M4S@2|Bacteria,46WNN@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_165724_4	1396418.BATQ01000076_gene732	3.827e-142	467.0	COG0126@1|root,COG0126@2|Bacteria,46SI9@74201|Verrucomicrobia,2ITXY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Phosphoglycerate kinase	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
CH3_k127_165724_7	452637.Oter_3825	2.035e-86	292.0	COG0149@1|root,COG0149@2|Bacteria,46SNB@74201|Verrucomicrobia,3K7RD@414999|Opitutae	414999|Opitutae	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
CH3_k127_165724_20	278957.ABEA03000211_gene3535	1.148e-10	67.0	COG1314@1|root,COG1314@2|Bacteria,46T75@74201|Verrucomicrobia,3K89V@414999|Opitutae	414999|Opitutae	U	PFAM Preprotein translocase SecG subunit	-	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
CH3_k127_165724_3	1403819.BATR01000065_gene1925	2.191e-143	478.0	COG4166@1|root,COG4166@2|Bacteria,46SBG@74201|Verrucomicrobia,2ITVI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
CH3_k127_165724_10	1192034.CAP_8072	3.761e-83	286.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,43AFB@68525|delta/epsilon subdivisions,2X5XK@28221|Deltaproteobacteria,2Z2YK@29|Myxococcales	28221|Deltaproteobacteria	EP	Binding-protein-dependent transport system inner membrane component	appB	-	-	ko:K02033,ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
CH3_k127_165724_8	497964.CfE428DRAFT_3544	7.406e-85	294.0	COG1173@1|root,COG1173@2|Bacteria,46SN0@74201|Verrucomicrobia	74201|Verrucomicrobia	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
CH3_k127_165724_2	278957.ABEA03000130_gene1696	9.179e-146	478.0	COG2805@1|root,COG2805@2|Bacteria,46S5Q@74201|Verrucomicrobia,3K79X@414999|Opitutae	2|Bacteria	NU	twitching motility protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
CH3_k127_165724_9	278957.ABEA03000130_gene1697	1.952e-83	288.0	COG0457@1|root,COG0457@2|Bacteria	278957.ABEA03000130_gene1697|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_165724_19	278957.ABEA03000130_gene1699	8.648e-18	84.0	2EJWH@1|root,33DM6@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2997)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2997
CH3_k127_165724_1	278957.ABEA03000130_gene1701	8.64e-241	754.0	COG0464@1|root,COG0464@2|Bacteria	2|Bacteria	O	ATPase activity	ycf46	-	3.6.4.6	ko:K06027	ko04138,ko04721,ko04727,ko04962,map04138,map04721,map04727,map04962	-	-	-	ko00000,ko00001,ko01000,ko04131	1.F.1.1	-	-	AAA
CH3_k127_165724_5	278957.ABEA03000130_gene1703	8.509e-94	319.0	COG1313@1|root,COG1313@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Radical_SAM
CH3_k127_165724_11	278957.ABEA03000130_gene1706	1.215e-62	220.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	sigE1	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CH3_k127_165724_15	497964.CfE428DRAFT_4274	2.231e-32	130.0	COG1925@1|root,COG1925@2|Bacteria,46T6C@74201|Verrucomicrobia	74201|Verrucomicrobia	G	TIGRFAM phosphocarrier, HPr family	fruB	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
CH3_k127_165724_13	497964.CfE428DRAFT_4273	8.151e-47	171.0	COG1493@1|root,COG1493@2|Bacteria,46S64@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
CH3_k127_1663108_0	497964.CfE428DRAFT_4093	0.0	1282.0	COG0506@1|root,COG1012@1|root,COG0506@2|Bacteria,COG1012@2|Bacteria,46SAP@74201|Verrucomicrobia	74201|Verrucomicrobia	CE	Proline dehydrogenase	-	-	1.2.1.88,1.5.5.2	ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh,Pro_dh-DNA_bdg
CH3_k127_1663108_1	240016.ABIZ01000001_gene887	8.106e-87	289.0	COG1063@1|root,COG1063@2|Bacteria,46UMA@74201|Verrucomicrobia,2ITX5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Alcohol dehydrogenase GroES-like domain	tdh	-	1.1.1.103	ko:K00060	ko00260,map00260	-	R01465	RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CH3_k127_1666192_2	478741.JAFS01000002_gene722	7.358e-45	169.0	COG0124@1|root,COG0124@2|Bacteria,46S7Y@74201|Verrucomicrobia,37G1T@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	J	Histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
CH3_k127_1666192_3	497964.CfE428DRAFT_0567	9.702e-45	165.0	COG0335@1|root,COG0335@2|Bacteria,46T0S@74201|Verrucomicrobia	74201|Verrucomicrobia	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
CH3_k127_1666192_1	235909.GK1201	5.703e-87	293.0	COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,4HBFV@91061|Bacilli,1WE2C@129337|Geobacillus	91061|Bacilli	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
CH3_k127_1666192_5	289376.THEYE_A0819	3.69e-17	83.0	COG1837@1|root,COG1837@2|Bacteria	2|Bacteria	L	Belongs to the UPF0109 family	ylqC	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
CH3_k127_1666192_4	632518.Calow_0752	7.97e-24	102.0	COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,24MND@186801|Clostridia,42GTF@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
CH3_k127_1666192_0	880072.Desac_0610	8.063e-138	469.0	COG0863@1|root,COG0863@2|Bacteria,1R8XS@1224|Proteobacteria	1224|Proteobacteria	L	DNA methylase	-	-	2.1.1.113	ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
CH3_k127_1666192_6	452637.Oter_0312	6.761e-07	63.0	COG3291@1|root,COG3386@1|root,COG3291@2|Bacteria,COG3386@2|Bacteria,46ZJT@74201|Verrucomicrobia	2|Bacteria	G	Immunoglobulin I-set domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,He_PIG,PKD
CH3_k127_1668907_6	686340.Metal_2200	1.102e-29	128.0	2C6BE@1|root,32XBJ@2|Bacteria,1NB89@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_1668907_8	1232410.KI421421_gene3334	1.964e-11	75.0	2DT2H@1|root,33IDP@2|Bacteria,1NXAG@1224|Proteobacteria,430YG@68525|delta/epsilon subdivisions,2WVZY@28221|Deltaproteobacteria,43VAJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2959
CH3_k127_1668907_3	243233.MCA1632	6.26e-102	363.0	COG1196@1|root,COG3264@1|root,COG1196@2|Bacteria,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,1RMYY@1236|Gammaproteobacteria,1XE6E@135618|Methylococcales	135618|Methylococcales	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
CH3_k127_1668907_4	690850.Desaf_1399	4.018e-50	199.0	COG3746@1|root,COG3746@2|Bacteria,1RA39@1224|Proteobacteria,43ESD@68525|delta/epsilon subdivisions,2X9MI@28221|Deltaproteobacteria,2MF6N@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Phosphate-selective porin O and P	-	-	-	ko:K07221	-	-	-	-	ko00000,ko02000	1.B.5.1	-	-	Porin_O_P
CH3_k127_1668907_2	497964.CfE428DRAFT_5778	2.283e-102	345.0	28HK0@1|root,2Z7V0@2|Bacteria,46TSH@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
CH3_k127_1668907_1	1304885.AUEY01000019_gene1169	1.136e-135	457.0	COG1075@1|root,COG1075@2|Bacteria,1NYAK@1224|Proteobacteria,42Q3C@68525|delta/epsilon subdivisions,2WMAK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
CH3_k127_1668907_7	926566.Terro_1693	5.692e-17	88.0	COG2823@1|root,COG2823@2|Bacteria,3Y4FV@57723|Acidobacteria,2JJ5I@204432|Acidobacteriia	204432|Acidobacteriia	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
CH3_k127_1668907_0	1123242.JH636435_gene2020	8.23e-271	842.0	COG2407@1|root,COG2407@2|Bacteria,2IXT8@203682|Planctomycetes	203682|Planctomycetes	G	Converts the aldose L-fucose into the corresponding ketose L-fuculose	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_1668907_5	1117318.PRUB_19819	2.368e-47	181.0	COG1404@1|root,COG3291@1|root,COG4935@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,COG4935@2|Bacteria,1MU3S@1224|Proteobacteria,1RSP9@1236|Gammaproteobacteria,2Q10K@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	PKD,P_proprotein,Peptidase_S8
CH3_k127_1671780_2	595460.RRSWK_06974	9.036e-31	138.0	COG1404@1|root,COG3291@1|root,COG5337@1|root,COG5549@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,COG5337@2|Bacteria,COG5549@2|Bacteria,2IYR8@203682|Planctomycetes	203682|Planctomycetes	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH
CH3_k127_1671780_0	1122605.KB893637_gene3257	6.652e-44	184.0	COG3533@1|root,COG3533@2|Bacteria,4NFW3@976|Bacteroidetes	976|Bacteroidetes	G	glycosyl hydrolase of	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
CH3_k127_1671780_1	595460.RRSWK_03845	5.703e-42	177.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
CH3_k127_1688991_2	497964.CfE428DRAFT_5370	9.122e-29	116.0	COG2255@1|root,COG2255@2|Bacteria,46SDS@74201|Verrucomicrobia	74201|Verrucomicrobia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
CH3_k127_1688991_0	234267.Acid_0830	8.023e-241	759.0	COG2936@1|root,COG2936@2|Bacteria,3Y2WR@57723|Acidobacteria	57723|Acidobacteria	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
CH3_k127_1688991_1	190650.CC_3489	2.524e-133	444.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,2VF1X@28211|Alphaproteobacteria,2KK2H@204458|Caulobacterales	204458|Caulobacterales	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CH3_k127_1688991_4	1173026.Glo7428_0087	1.963e-06	51.0	COG0265@1|root,COG0265@2|Bacteria,1G3M4@1117|Cyanobacteria	1117|Cyanobacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
CH3_k127_1688991_3	1123508.JH636439_gene1125	2.568e-24	114.0	COG0457@1|root,COG0457@2|Bacteria	1123508.JH636439_gene1125|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_169445_1	1123278.KB893616_gene3404	4.83e-140	459.0	COG3408@1|root,COG3408@2|Bacteria,4NHST@976|Bacteroidetes,47KY3@768503|Cytophagia	976|Bacteroidetes	G	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H,Bac_rhamnosid_C
CH3_k127_169445_2	234267.Acid_5934	8.256e-139	451.0	COG0697@1|root,2Z7ID@2|Bacteria,3Y46C@57723|Acidobacteria	57723|Acidobacteria	EG	PFAM RhaT l-rhamnose-proton symport 2	-	-	-	ko:K02856	-	-	-	-	ko00000,ko02000	2.A.7.6	-	-	RhaT
CH3_k127_169445_0	886293.Sinac_6992	1.359e-190	608.0	COG4806@1|root,COG4806@2|Bacteria,2IXTQ@203682|Planctomycetes	203682|Planctomycetes	G	L-rhamnose isomerase	rhaA	GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0008740,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0019321,GO:0019324,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575	5.3.1.14	ko:K01813	ko00051,ko01120,map00051,map01120	-	R02437	RC00434	ko00000,ko00001,ko01000	-	-	-	RhaA
CH3_k127_169445_3	1121481.AUAS01000002_gene3607	1.142e-10	66.0	COG0221@1|root,COG0221@2|Bacteria,4PBT1@976|Bacteroidetes,47WA3@768503|Cytophagia	976|Bacteroidetes	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_1704570_0	1121468.AUBR01000038_gene1965	1.281e-170	552.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1TR8J@1239|Firmicutes,247RR@186801|Clostridia,42HW6@68295|Thermoanaerobacterales	186801|Clostridia	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
CH3_k127_1704570_1	357808.RoseRS_2969	5.707e-162	518.0	COG0183@1|root,COG0183@2|Bacteria,2G5YW@200795|Chloroflexi,3755G@32061|Chloroflexia	32061|Chloroflexia	I	Belongs to the thiolase family	-	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
CH3_k127_1704570_2	1123242.JH636434_gene5140	5.469e-103	341.0	COG2086@1|root,COG2086@2|Bacteria	2|Bacteria	C	electron transfer activity	etfB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
CH3_k127_1704570_3	1123242.JH636434_gene5139	2.917e-55	201.0	COG2025@1|root,COG2025@2|Bacteria,2J3Y1@203682|Planctomycetes	203682|Planctomycetes	C	Electron transfer flavoprotein domain	-	-	-	-	-	-	-	-	-	-	-	-	ETF,ETF_alpha
CH3_k127_1714003_3	1123242.JH636435_gene2999	4.681e-57	200.0	COG0156@1|root,COG0156@2|Bacteria,2IX0H@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CH3_k127_1714003_0	497964.CfE428DRAFT_4082	9.954e-151	488.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF3472,DUF5077,Gram_pos_anchor,Reprolysin_4
CH3_k127_1714003_5	1403819.BATR01000151_gene5104	2.607e-28	135.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,HemolysinCabind,PATR
CH3_k127_1714003_4	1403819.BATR01000069_gene2031	2.733e-39	171.0	COG1470@1|root,COG1749@1|root,COG3291@1|root,COG3506@1|root,COG3533@1|root,COG1470@2|Bacteria,COG1749@2|Bacteria,COG3291@2|Bacteria,COG3506@2|Bacteria,COG3533@2|Bacteria,46SQ1@74201|Verrucomicrobia,2IV3A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	N	Erythromycin esterase	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_1714003_6	376686.Fjoh_2456	9.908e-12	80.0	COG3866@1|root,COG3866@2|Bacteria,4NJUK@976|Bacteroidetes,1IIIB@117743|Flavobacteriia,2NUS2@237|Flavobacterium	976|Bacteroidetes	G	Pectate lyase	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_1714003_7	980584.AFPB01000131_gene3192	1.328e-06	63.0	COG2730@1|root,COG3401@1|root,COG2730@2|Bacteria,COG3401@2|Bacteria,4PPCW@976|Bacteroidetes,1I8FJ@117743|Flavobacteriia,4079T@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_1714003_2	697281.Mahau_0407	1.556e-71	257.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,2497G@186801|Clostridia,42F5Y@68295|Thermoanaerobacterales	186801|Clostridia	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CH3_k127_1714003_1	497964.CfE428DRAFT_4093	6.296e-91	306.0	COG0506@1|root,COG1012@1|root,COG0506@2|Bacteria,COG1012@2|Bacteria,46SAP@74201|Verrucomicrobia	74201|Verrucomicrobia	CE	Proline dehydrogenase	-	-	1.2.1.88,1.5.5.2	ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh,Pro_dh-DNA_bdg
CH3_k127_1747712_2	595460.RRSWK_04701	2.979e-50	199.0	COG3828@1|root,COG3828@2|Bacteria	2|Bacteria	N	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CH3_k127_1747712_1	1123508.JH636449_gene7307	5.068e-68	241.0	COG5306@1|root,COG5306@2|Bacteria,2J543@203682|Planctomycetes	203682|Planctomycetes	S	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_1747712_4	1122971.BAME01000072_gene5042	4.734e-21	106.0	COG5434@1|root,COG5434@2|Bacteria,4NG4T@976|Bacteroidetes,2FNB1@200643|Bacteroidia,22XCH@171551|Porphyromonadaceae	2|Bacteria	M	Glycosyl hydrolases family 28	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Glyco_hydro_28,Pectate_lyase_3
CH3_k127_1747712_0	313628.LNTAR_01322	3.213e-206	663.0	2DUCG@1|root,33PYM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_1747712_3	1211813.CAPH01000009_gene34	3.165e-39	168.0	COG3533@1|root,COG3533@2|Bacteria	2|Bacteria	S	Beta-L-arabinofuranosidase, GH127	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,Laminin_G_3
CH3_k127_1748198_1	497964.CfE428DRAFT_2266	2.746e-192	607.0	COG0477@1|root,COG2814@2|Bacteria,46U08@74201|Verrucomicrobia	74201|Verrucomicrobia	EGP	Nucleoside H+ symporter	-	-	-	-	-	-	-	-	-	-	-	-	Nuc_H_symport
CH3_k127_1748198_2	497964.CfE428DRAFT_0193	5.135e-111	364.0	COG1210@1|root,COG1210@2|Bacteria,46S5P@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Utp--glucose-1-phosphate uridylyltransferase	-	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
CH3_k127_1748198_0	497964.CfE428DRAFT_0194	0.0	1649.0	COG4284@1|root,COG4284@2|Bacteria,46SCH@74201|Verrucomicrobia	74201|Verrucomicrobia	H	UTP--glucose-1-phosphate uridylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	UDPGP
CH3_k127_1748198_6	349741.Amuc_0256	1.606e-27	120.0	COG0801@1|root,COG0801@2|Bacteria,46T2Z@74201|Verrucomicrobia,2IUKW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	-	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
CH3_k127_1748198_5	497964.CfE428DRAFT_0873	1.463e-89	301.0	COG0289@1|root,COG0289@2|Bacteria,46SPR@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
CH3_k127_1748198_3	478741.JAFS01000002_gene313	2.94e-104	349.0	COG0329@1|root,COG0329@2|Bacteria,46SDY@74201|Verrucomicrobia,37G2R@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	EM	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
CH3_k127_1748198_4	112098.XP_008616287.1	1.49e-91	309.0	COG0253@1|root,2QQKJ@2759|Eukaryota	2759|Eukaryota	E	diaminopimelate epimerase activity	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
CH3_k127_175926_4	313628.LNTAR_00920	2.018e-61	224.0	COG3669@1|root,COG3669@2|Bacteria	2|Bacteria	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,F5_F8_type_C
CH3_k127_175926_0	661478.OP10G_0382	7.331e-282	896.0	COG2605@1|root,COG2605@2|Bacteria	2|Bacteria	G	GHMP kinase	fkp	-	2.7.1.52	ko:K05305	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R03161	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	Fucokinase,GHMP_kinases_C,GHMP_kinases_N
CH3_k127_175926_1	661478.OP10G_0366	2.266e-172	548.0	COG4030@1|root,COG4030@2|Bacteria	2|Bacteria	M	Protein of unknown function (DUF2961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
CH3_k127_175926_2	204669.Acid345_3213	1.247e-91	307.0	COG0563@1|root,COG0563@2|Bacteria,3Y421@57723|Acidobacteria,2JI14@204432|Acidobacteriia	57723|Acidobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	-	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
CH3_k127_175926_3	1168034.FH5T_21220	1.123e-82	284.0	COG0667@1|root,COG0667@2|Bacteria,4NP8D@976|Bacteroidetes,2FTGW@200643|Bacteroidia	976|Bacteroidetes	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CH3_k127_1765673_7	186497.PF0730	1.195e-37	154.0	arCOG07124@1|root,arCOG07124@2157|Archaea,2Y6Q6@28890|Euryarchaeota,2451X@183968|Thermococci	183968|Thermococci	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_1765673_15	330214.NIDE1608	6.979e-17	89.0	COG0296@1|root,COG0296@2|Bacteria	2|Bacteria	G	1,4-alpha-glucan branching enzyme activity	-	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	AMPK1_CBM,Alpha-amylase,Alpha-amylase_C,CBM_48
CH3_k127_1765673_20	452637.Oter_1161	4.109e-06	53.0	COG4575@1|root,COG4575@2|Bacteria,46WFC@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Bacterial protein of unknown function (DUF883)	-	-	-	-	-	-	-	-	-	-	-	-	DUF883
CH3_k127_1765673_21	1410608.JNKX01000052_gene1502	8.511e-06	56.0	COG3385@1|root,COG3385@2|Bacteria,4NXT2@976|Bacteroidetes,2FRVS@200643|Bacteroidia	976|Bacteroidetes	L	hmm pf01609	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
CH3_k127_1765673_4	521011.Mpal_2572	7.831e-67	235.0	COG4063@1|root,arCOG03221@2157|Archaea	2157|Archaea	H	Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step	mtrA-2	-	2.1.1.86	ko:K00577	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00357,M00567	R04347	RC00035,RC00113,RC02892	ko00000,ko00001,ko00002,ko01000	-	-	-	MtrA
CH3_k127_1765673_6	1283300.ATXB01000001_gene1577	4.532e-44	167.0	COG0589@1|root,COG0589@2|Bacteria,1NGA1@1224|Proteobacteria	1224|Proteobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CH3_k127_1765673_17	1283300.ATXB01000001_gene1577	1.269e-15	79.0	COG0589@1|root,COG0589@2|Bacteria,1NGA1@1224|Proteobacteria	1224|Proteobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CH3_k127_1765673_1	478741.JAFS01000001_gene1976	5.099e-147	477.0	COG0798@1|root,COG0798@2|Bacteria,46UD3@74201|Verrucomicrobia,37FUU@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	P	Sodium Bile acid symporter family	-	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
CH3_k127_1765673_9	1156937.MFUM_270017	5.351e-30	132.0	COG2866@1|root,COG2866@2|Bacteria,46T00@74201|Verrucomicrobia,37GID@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	E	Protein of unknown function (DUF2817)	-	-	-	-	-	-	-	-	-	-	-	-	AstE_AspA
CH3_k127_1765673_22	1112216.JH594425_gene2614	0.0001643	51.0	COG0642@1|root,COG1352@1|root,COG2201@1|root,COG4566@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,COG2205@2|Bacteria,COG4566@2|Bacteria,1NRP8@1224|Proteobacteria,2TWP9@28211|Alphaproteobacteria,2KETS@204457|Sphingomonadales	204457|Sphingomonadales	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	CheB_methylest,CheR,CheR_N,GerE,HATPase_c,HisKA,PAS_10,Response_reg
CH3_k127_1765673_16	794903.OPIT5_07895	2.691e-16	80.0	COG2331@1|root,COG2331@2|Bacteria,46ZFV@74201|Verrucomicrobia,3K8G5@414999|Opitutae	414999|Opitutae	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_1765673_0	530564.Psta_1209	1.385e-216	696.0	COG0003@1|root,COG0003@2|Bacteria,2IY37@203682|Planctomycetes	203682|Planctomycetes	P	TIGRFAM arsenite-activated ATPase (arsA)	-	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
CH3_k127_1765673_10	1269813.ATUL01000021_gene759	3.876e-27	127.0	2DMHQ@1|root,32RMG@2|Bacteria,1RI3A@1224|Proteobacteria,1S7NG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Arsenical resistance operon trans-acting repressor arsD	arsD	-	-	-	-	-	-	-	-	-	-	-	ArsD
CH3_k127_1765673_2	556269.ACDQ01000009_gene1948	2.403e-95	331.0	COG0500@1|root,COG2226@2|Bacteria,1MVXN@1224|Proteobacteria,2VQVG@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Methyltransferase type 11	arsM	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
CH3_k127_1765673_18	344747.PM8797T_22568	2.555e-08	59.0	2EPBI@1|root,33GYA@2|Bacteria,2J1HU@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_1765673_3	1396141.BATP01000003_gene5267	5.248e-71	244.0	COG0394@1|root,COG0394@2|Bacteria,46T52@74201|Verrucomicrobia,2IUEU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Low molecular weight phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	LMWPc
CH3_k127_1765673_8	278957.ABEA03000004_gene4516	1.741e-34	138.0	COG0640@1|root,COG0640@2|Bacteria,46WF9@74201|Verrucomicrobia,3K8BI@414999|Opitutae	414999|Opitutae	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
CH3_k127_1765673_14	1408428.JNJP01000055_gene143	1.21e-18	91.0	COG0640@1|root,COG0640@2|Bacteria,1MZT1@1224|Proteobacteria,42V3T@68525|delta/epsilon subdivisions,2WS3M@28221|Deltaproteobacteria,2MC9Y@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	Helix-turn-helix domain	-	-	-	ko:K03892,ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
CH3_k127_1765673_19	521674.Plim_0147	7.594e-08	61.0	2DMHQ@1|root,32RMG@2|Bacteria,2J02C@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Arsenical resistance operon trans-acting repressor ArsD	-	-	-	-	-	-	-	-	-	-	-	-	ArsD
CH3_k127_1765673_13	1304885.AUEY01000001_gene3204	5.788e-20	101.0	2DPAK@1|root,33193@2|Bacteria,1NDU6@1224|Proteobacteria,432ZD@68525|delta/epsilon subdivisions,2WYIN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_1765673_12	402880.MmarC5_0718	3.513e-21	102.0	COG0655@1|root,arCOG02573@2157|Archaea,2XVMU@28890|Euryarchaeota,23QEP@183939|Methanococci	183939|Methanococci	S	PFAM NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
CH3_k127_1765673_5	909663.KI867150_gene1425	2.556e-58	204.0	COG4232@1|root,COG4232@2|Bacteria,1PK9S@1224|Proteobacteria,42PV0@68525|delta/epsilon subdivisions,2WJPK@28221|Deltaproteobacteria,2MS43@213462|Syntrophobacterales	28221|Deltaproteobacteria	CO	PFAM cytochrome c biogenesis protein, transmembrane region	dsbD	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
CH3_k127_1778446_4	1157490.EL26_23840	5.609e-16	80.0	COG1641@1|root,COG1641@2|Bacteria,1TPAV@1239|Firmicutes,4HC7I@91061|Bacilli,279D9@186823|Alicyclobacillaceae	91061|Bacilli	S	Protein of unknown function DUF111	larC	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
CH3_k127_1778446_0	933262.AXAM01000001_gene380	7.679e-104	353.0	COG0318@1|root,COG0318@2|Bacteria,1NRID@1224|Proteobacteria,43CJB@68525|delta/epsilon subdivisions,2X7TP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
CH3_k127_1778446_5	1192034.CAP_6765	4.286e-05	49.0	COG0236@1|root,COG0236@2|Bacteria	2|Bacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	-	GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016999,GO:0017000,GO:0017144,GO:0044237,GO:0044249	-	ko:K21781	ko00333,map00333	M00837,M00838	R06746	RC00039,RC01438	ko00000,ko00001,ko00002	-	-	-	PP-binding
CH3_k127_1778446_3	1116472.MGMO_20c00250	1.825e-21	108.0	COG1020@1|root,COG1020@2|Bacteria,1NK69@1224|Proteobacteria,1SKZR@1236|Gammaproteobacteria,1XFVG@135618|Methylococcales	135618|Methylococcales	Q	D-alanine [D-alanyl carrier protein] ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_1778446_2	933262.AXAM01000001_gene381	7.757e-36	154.0	COG0644@1|root,COG0644@2|Bacteria,1QM8G@1224|Proteobacteria	1224|Proteobacteria	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
CH3_k127_1778446_1	746697.Aeqsu_0908	9.147e-41	162.0	COG1541@1|root,COG1541@2|Bacteria,4NGRR@976|Bacteroidetes,1HZ2J@117743|Flavobacteriia	976|Bacteroidetes	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	paaK	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
CH3_k127_1833139_2	530564.Psta_1162	1.958e-176	556.0	COG3119@1|root,COG3119@2|Bacteria,2IYNT@203682|Planctomycetes	203682|Planctomycetes	P	Sulfatase	-	-	3.1.6.12	ko:K01135	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00076,M00077	R07823	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Sulfatase
CH3_k127_1833139_0	1038860.AXAP01000015_gene2094	0.0	1435.0	COG3957@1|root,COG3957@2|Bacteria,1MVSE@1224|Proteobacteria,2TU2E@28211|Alphaproteobacteria,3JRH2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	aldehyde-lyase activity	xfp	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
CH3_k127_1833139_3	1449049.JONW01000013_gene4657	9.532e-117	405.0	COG5164@1|root,COG5164@2|Bacteria,1MX1Z@1224|Proteobacteria,2TWHE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	regulation of DNA-templated transcription, elongation	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_1833139_1	497964.CfE428DRAFT_1137	0.0	1032.0	COG0282@1|root,COG4869@1|root,COG0282@2|Bacteria,COG4869@2|Bacteria,46SKB@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase,PTAC,cNMP_binding
CH3_k127_1833139_4	720554.Clocl_1150	3.519e-22	97.0	COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,249AM@186801|Clostridia,3WGG1@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA2	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
CH3_k127_1839390_3	530564.Psta_1454	1.905e-139	447.0	COG0274@1|root,COG0274@2|Bacteria,2IWY0@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
CH3_k127_1839390_9	313612.L8106_06989	1.557e-20	97.0	COG2337@1|root,COG2337@2|Bacteria,1G72T@1117|Cyanobacteria,1HDXS@1150|Oscillatoriales	1117|Cyanobacteria	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
CH3_k127_1839390_10	530564.Psta_1454	3.656e-14	73.0	COG0274@1|root,COG0274@2|Bacteria,2IWY0@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
CH3_k127_1839390_7	530564.Psta_4484	3.138e-124	412.0	COG0673@1|root,COG0673@2|Bacteria,2IXE4@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CH3_k127_1839390_5	240016.ABIZ01000001_gene54	2.154e-133	439.0	COG3356@1|root,COG3356@2|Bacteria,46XH2@74201|Verrucomicrobia,2IVWJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Neutral/alkaline non-lysosomal ceramidase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
CH3_k127_1839390_4	1195236.CTER_2031	2.843e-134	439.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,24G9G@186801|Clostridia	186801|Clostridia	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
CH3_k127_1839390_6	641524.ADICYQ_2925	2.245e-128	419.0	COG0673@1|root,COG0673@2|Bacteria,4NFY3@976|Bacteroidetes,47ME7@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CH3_k127_1839390_11	925775.XVE_1359	4.706e-06	51.0	2CA82@1|root,2ZP0Q@2|Bacteria,1NDH6@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	DUF3658
CH3_k127_1839390_1	497964.CfE428DRAFT_1842	3.535e-154	490.0	COG1082@1|root,COG1082@2|Bacteria,46U2S@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CH3_k127_1839390_8	1550091.JROE01000002_gene502	1.839e-92	319.0	2DBWR@1|root,2ZBIN@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4838)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4838
CH3_k127_1839390_2	497964.CfE428DRAFT_6195	5.502e-142	460.0	COG0673@1|root,COG0673@2|Bacteria,46UE3@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CH3_k127_1839390_0	1123278.KB893542_gene5513	5.009e-191	604.0	COG4225@1|root,COG4225@2|Bacteria,4NJYK@976|Bacteroidetes,47MFS@768503|Cytophagia	976|Bacteroidetes	S	Glycosyl Hydrolase Family 88	-	-	3.2.1.180	ko:K18581	-	-	R10867	RC00049,RC02427	ko00000,ko01000	-	GH88	-	Glyco_hydro_88
CH3_k127_1876728_9	192952.MM_3371	1.025e-06	55.0	arCOG06820@1|root,arCOG06820@2157|Archaea,2XVYD@28890|Euryarchaeota,2N917@224756|Methanomicrobia	224756|Methanomicrobia	S	YoaP-like	-	-	-	-	-	-	-	-	-	-	-	-	YoaP
CH3_k127_1876728_8	1268237.G114_09454	7.207e-25	108.0	2EGMM@1|root,33ADT@2|Bacteria,1R0Q0@1224|Proteobacteria,1T4N8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_4
CH3_k127_1876728_7	481448.Minf_2259	2.539e-78	270.0	COG0084@1|root,COG0084@2|Bacteria,46SKF@74201|Verrucomicrobia,37GKS@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	L	TatD related DNase	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
CH3_k127_1876728_0	497964.CfE428DRAFT_6291	2.707e-169	544.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,Copper-bind,Cytochrom_C,Laminin_G_3
CH3_k127_1876728_6	497964.CfE428DRAFT_2488	4.808e-79	285.0	COG0457@1|root,COG0457@2|Bacteria,46SRS@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_1876728_4	497964.CfE428DRAFT_2489	4.908e-83	283.0	COG1235@1|root,COG1235@2|Bacteria,46SRW@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Beta-lactamase superfamily domain	-	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
CH3_k127_1876728_2	497964.CfE428DRAFT_2490	1.976e-157	518.0	COG0497@1|root,COG0497@2|Bacteria,46SGB@74201|Verrucomicrobia	74201|Verrucomicrobia	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
CH3_k127_1876728_1	1123242.JH636434_gene3280	4.109e-158	511.0	COG0823@1|root,COG0823@2|Bacteria,2IYQ1@203682|Planctomycetes	203682|Planctomycetes	U	Protein of unknown function (DUF3748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3748,PD40
CH3_k127_1876728_5	269799.Gmet_2367	8.577e-80	288.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,42MPS@68525|delta/epsilon subdivisions,2WIUD@28221|Deltaproteobacteria,43TVN@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
CH3_k127_1876728_3	1211777.BN77_p2190020	1.181e-117	389.0	COG0451@1|root,COG0451@2|Bacteria,1MW3K@1224|Proteobacteria,2TTTJ@28211|Alphaproteobacteria,4BCIX@82115|Rhizobiaceae	28211|Alphaproteobacteria	GM	NAD(P)H-binding	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
CH3_k127_1905414_12	886293.Sinac_7506	1.274e-09	69.0	COG1413@1|root,COG1413@2|Bacteria,2J011@203682|Planctomycetes	203682|Planctomycetes	C	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
CH3_k127_1905414_0	497964.CfE428DRAFT_5670	1.989e-210	670.0	COG0405@1|root,COG0405@2|Bacteria,46SGY@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
CH3_k127_1905414_2	861299.J421_3611	1.2e-148	482.0	COG1301@1|root,COG1301@2|Bacteria,1ZT91@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Sodium:dicarboxylate symporter family	-	-	-	ko:K11102	-	-	-	-	ko00000,ko02000	2.A.23.1.1,2.A.23.1.2	-	-	SDF
CH3_k127_1905414_8	1382356.JQMP01000004_gene323	5.322e-88	301.0	COG3804@1|root,COG3804@2|Bacteria,2GA3D@200795|Chloroflexi,27YZV@189775|Thermomicrobia	189775|Thermomicrobia	S	Dihydrodipicolinate reductase, N-terminus	-	-	1.4.1.12,1.4.1.26	ko:K21672	ko00310,ko00330,ko00472,map00310,map00330,map00472	-	R02825,R04200,R04201,R04687,R04688	RC00249,RC00790	ko00000,ko00001,ko01000	-	-	-	DapB_N
CH3_k127_1905414_10	1396141.BATP01000057_gene2952	1.772e-72	256.0	COG1475@1|root,COG1475@2|Bacteria,46SQ8@74201|Verrucomicrobia,2IU4T@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	ParB-like nuclease domain	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
CH3_k127_1905414_7	1414720.CBYM010000003_gene388	3.968e-97	329.0	COG0524@1|root,COG0524@2|Bacteria,1V4QY@1239|Firmicutes,24HRA@186801|Clostridia,36S3G@31979|Clostridiaceae	186801|Clostridia	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
CH3_k127_1905414_11	497964.CfE428DRAFT_6518	1.163e-49	193.0	COG0242@1|root,COG0242@2|Bacteria,46SYF@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
CH3_k127_1905414_1	344747.PM8797T_13063	2.516e-171	552.0	COG3119@1|root,COG3119@2|Bacteria,2IXUN@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CH3_k127_1905414_3	1123242.JH636434_gene3814	2.113e-146	476.0	COG3119@1|root,COG3119@2|Bacteria,2IY75@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.8	ko:K01134	ko00600,ko04142,map00600,map04142	-	R04856	RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
CH3_k127_1905414_4	95619.PM1_0204860	4.876e-132	433.0	COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,1RMAY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0055129,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	iB21_1397.B21_00243,iECBD_1354.ECBD_3376,iECB_1328.ECB_00240,iECD_1391.ECD_00240,iYL1228.KPN_00280	Aldedh
CH3_k127_1905414_13	388467.A19Y_2770	0.0001133	51.0	COG4636@1|root,COG4636@2|Bacteria,1G4JH@1117|Cyanobacteria,1H9Q5@1150|Oscillatoriales	1117|Cyanobacteria	S	protein conserved in cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
CH3_k127_1905414_5	497964.CfE428DRAFT_4568	8.653e-127	422.0	28MGX@1|root,2ZATZ@2|Bacteria,46TJV@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_1905414_9	945713.IALB_0134	4.734e-85	299.0	COG0572@1|root,COG0572@2|Bacteria	2|Bacteria	F	uridine kinase	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
CH3_k127_1905414_6	266834.SM_b21056	8.372e-103	376.0	COG3291@1|root,COG3828@1|root,COG3291@2|Bacteria,COG3828@2|Bacteria	2|Bacteria	N	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,UnbV_ASPIC,VCBS
CH3_k127_1910312_4	794903.OPIT5_07325	1.499e-18	92.0	COG0499@1|root,COG0499@2|Bacteria,46SGX@74201|Verrucomicrobia,3K76U@414999|Opitutae	414999|Opitutae	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
CH3_k127_1910312_6	1120949.KB903306_gene7572	1.103e-05	59.0	COG1361@1|root,COG2304@1|root,COG1361@2|Bacteria,COG2304@2|Bacteria,2I8F1@201174|Actinobacteria,4DFBB@85008|Micromonosporales	201174|Actinobacteria	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF3344
CH3_k127_1910312_3	383372.Rcas_0336	5.561e-25	122.0	COG0515@1|root,COG0515@2|Bacteria,2GACY@200795|Chloroflexi,375GK@32061|Chloroflexia	32061|Chloroflexia	KLT	SMART tyrosine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CH3_k127_1910312_5	935863.AWZR01000007_gene245	2.068e-11	67.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,1RMW8@1236|Gammaproteobacteria,1X33V@135614|Xanthomonadales	135614|Xanthomonadales	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
CH3_k127_1910312_1	452637.Oter_0623	2.064e-55	199.0	COG3428@1|root,COG3428@2|Bacteria,46VXR@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Bacterial PH domain	-	-	-	ko:K08981	-	-	-	-	ko00000	-	-	-	bPH_2
CH3_k127_1910312_2	452637.Oter_0624	1.331e-47	183.0	COG3428@1|root,COG3428@2|Bacteria,46VTZ@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
CH3_k127_1910312_0	278957.ABEA03000091_gene684	1.028e-111	362.0	COG0499@1|root,COG0499@2|Bacteria,46SGX@74201|Verrucomicrobia,3K76U@414999|Opitutae	414999|Opitutae	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
CH3_k127_1914107_6	1304885.AUEY01000038_gene2556	3.426e-28	118.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,42Q3J@68525|delta/epsilon subdivisions,2WP5U@28221|Deltaproteobacteria,2MKDQ@213118|Desulfobacterales	28221|Deltaproteobacteria	M	TIGRFAM YD repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat,YwqJ-deaminase
CH3_k127_1914107_1	28072.Nos7524_1733	3.143e-222	699.0	COG3259@1|root,COG3259@2|Bacteria,1G1C8@1117|Cyanobacteria,1HMGB@1161|Nostocales	1117|Cyanobacteria	C	Coenzyme F420-reducing hydrogenase, alpha subunit	hoxH	-	1.12.1.2	ko:K00436	-	-	R00700	-	ko00000,ko01000	-	-	iJN678.hoxH	NiFeSe_Hases
CH3_k127_1914107_3	1173028.ANKO01000017_gene241	4.467e-70	249.0	COG1941@1|root,COG1941@2|Bacteria,1G2I6@1117|Cyanobacteria,1H9X3@1150|Oscillatoriales	1117|Cyanobacteria	C	Coenzyme F420-reducing hydrogenase, gamma subunit	hoxY	-	1.12.1.2	ko:K18007	-	-	-	-	ko00000,ko01000	-	-	iJN678.hoxY	Oxidored_q6
CH3_k127_1914107_2	1173028.ANKO01000017_gene242	7.228e-107	350.0	COG3383@1|root,COG3383@2|Bacteria,1G3GD@1117|Cyanobacteria,1H7Z2@1150|Oscillatoriales	1117|Cyanobacteria	C	NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G)	hoxU	-	1.6.5.3	ko:K05588	ko00190,ko01100,map00190,map01100	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Fer4_10,Fer4_6,Fer4_9,NADH-G_4Fe-4S_3
CH3_k127_1914107_0	98439.AJLL01000016_gene1689	6.789e-254	793.0	COG1894@1|root,COG1894@2|Bacteria,1G2KY@1117|Cyanobacteria	1117|Cyanobacteria	C	NADH ubiquinone oxidoreductase NADH-binding (51 kD) subunit	hoxF	-	1.6.5.3	ko:K05587	ko00190,ko01100,map00190,map01100	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
CH3_k127_1914107_4	251229.Chro_1157	1.242e-67	235.0	COG1905@1|root,COG1905@2|Bacteria,1G54V@1117|Cyanobacteria,3VJR9@52604|Pleurocapsales	1117|Cyanobacteria	C	PFAM Respiratory-chain NADH dehydrogenase 24 Kd subunit	hoxE	-	1.6.5.3	ko:K05586	ko00190,ko01100,map00190,map01100	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	2Fe-2S_thioredx
CH3_k127_1914107_5	497964.CfE428DRAFT_3286	3.204e-40	167.0	COG1928@1|root,COG1928@2|Bacteria,46UW1@74201|Verrucomicrobia	74201|Verrucomicrobia	O	C-terminal four TMM region of protein-O-mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_1927646_4	1069080.KB913028_gene310	3.321e-28	121.0	COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,4H210@909932|Negativicutes	909932|Negativicutes	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
CH3_k127_1927646_2	452637.Oter_2376	2.302e-59	209.0	COG1443@1|root,COG1443@2|Bacteria,46T1S@74201|Verrucomicrobia,3K84X@414999|Opitutae	414999|Opitutae	I	NUDIX hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CH3_k127_1927646_3	246197.MXAN_1687	1.278e-31	137.0	2A102@1|root,30P5F@2|Bacteria,1NQ9E@1224|Proteobacteria	1224|Proteobacteria	S	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF3592
CH3_k127_1927646_1	1156937.MFUM_170024	1.714e-87	295.0	COG0740@1|root,COG0740@2|Bacteria,46SAB@74201|Verrucomicrobia,37G7G@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
CH3_k127_1927646_0	511062.GU3_08515	4.755e-156	503.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,1RN9N@1236|Gammaproteobacteria,1Y3ZI@135624|Aeromonadales	135624|Aeromonadales	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
CH3_k127_1943325_6	1279009.ADICEAN_03353	1.988e-81	297.0	COG4547@1|root,COG4932@1|root,COG5644@1|root,COG4547@2|Bacteria,COG4932@2|Bacteria,COG5644@2|Bacteria,4PKCH@976|Bacteroidetes	976|Bacteroidetes	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,SdrD_B
CH3_k127_1943325_1	760192.Halhy_1406	7.925e-145	471.0	COG0673@1|root,COG0673@2|Bacteria,4NENY@976|Bacteroidetes	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CH3_k127_1943325_13	926569.ANT_03070	1.897e-26	128.0	COG5295@1|root,COG5295@2|Bacteria,2G7I4@200795|Chloroflexi	200795|Chloroflexi	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_1943325_15	324602.Caur_0299	3.561e-22	114.0	COG5295@1|root,COG5295@2|Bacteria,2GB82@200795|Chloroflexi,377IZ@32061|Chloroflexia	32061|Chloroflexia	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectinesterase
CH3_k127_1943325_12	111781.Lepto7376_0105	1.319e-38	168.0	COG1520@1|root,COG3210@1|root,COG3595@1|root,COG4995@1|root,COG1520@2|Bacteria,COG3210@2|Bacteria,COG3595@2|Bacteria,COG4995@2|Bacteria,1G08N@1117|Cyanobacteria,1H96Q@1150|Oscillatoriales	1117|Cyanobacteria	U	filamentous hemagglutinin family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,Haemagg_act,P_proprotein
CH3_k127_1943325_16	247490.KSU1_B0587	8.335e-11	76.0	COG0729@1|root,COG0729@2|Bacteria	2|Bacteria	M	surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,Peptidase_S74
CH3_k127_1943325_14	1297742.A176_05728	6.036e-25	112.0	COG5295@1|root,COG5295@2|Bacteria,1NI1M@1224|Proteobacteria,42ZTF@68525|delta/epsilon subdivisions,2WV01@28221|Deltaproteobacteria,2Z2QM@29|Myxococcales	28221|Deltaproteobacteria	UW	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74,YadA_head
CH3_k127_1943325_5	926569.ANT_30710	1.17e-87	300.0	COG1957@1|root,COG1957@2|Bacteria,2G7IF@200795|Chloroflexi	200795|Chloroflexi	F	PFAM Inosine uridine-preferring nucleoside hydrolase	-	-	3.2.2.1	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
CH3_k127_1943325_11	247490.KSU1_A0074	4.481e-41	156.0	COG0664@1|root,COG0664@2|Bacteria,2J0N9@203682|Planctomycetes	203682|Planctomycetes	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
CH3_k127_1943325_2	452637.Oter_4074	1.407e-112	373.0	COG2169@1|root,COG4936@1|root,COG2169@2|Bacteria,COG4936@2|Bacteria,46UZR@74201|Verrucomicrobia,3K795@414999|Opitutae	414999|Opitutae	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,PocR
CH3_k127_1943325_4	309807.SRU_0678	1.773e-105	355.0	COG3829@1|root,COG4585@1|root,COG3829@2|Bacteria,COG4585@2|Bacteria,4PI8P@976|Bacteroidetes,1FIMB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3,PAS
CH3_k127_1943325_7	452637.Oter_1551	1.637e-78	269.0	COG2197@1|root,COG2197@2|Bacteria,46SRM@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CH3_k127_1943325_9	313628.LNTAR_08349	2.601e-54	203.0	COG0472@1|root,COG0472@2|Bacteria	313628.LNTAR_08349|-	M	phospho-N-acetylmuramoyl-pentapeptide-transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_1943325_3	756272.Plabr_1226	1.386e-110	369.0	COG0438@1|root,COG0438@2|Bacteria,2IXN1@203682|Planctomycetes	203682|Planctomycetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CH3_k127_1943325_17	1122212.AULO01000008_gene1383	9.654e-06	59.0	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,1RQIX@1236|Gammaproteobacteria,1XI7D@135619|Oceanospirillales	135619|Oceanospirillales	H	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_6,TPR_8
CH3_k127_1943325_8	479434.Sthe_2682	6.712e-71	254.0	COG2265@1|root,COG2265@2|Bacteria,2G6IV@200795|Chloroflexi,27XG5@189775|Thermomicrobia	189775|Thermomicrobia	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	-	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
CH3_k127_1943325_0	1191523.MROS_0859	2.605e-236	743.0	COG2609@1|root,COG2609@2|Bacteria	2|Bacteria	C	pyruvate dehydrogenase (acetyl-transferring) activity	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
CH3_k127_1974226_3	1396141.BATP01000040_gene2191	4.025e-61	217.0	COG0673@1|root,COG0673@2|Bacteria,46U95@74201|Verrucomicrobia,2IVCR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CH3_k127_1974226_2	665956.HMPREF1032_00855	4.168e-98	331.0	COG0407@1|root,COG0407@2|Bacteria,1UY51@1239|Firmicutes,24E75@186801|Clostridia,3WPCX@541000|Ruminococcaceae	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
CH3_k127_1974226_4	382464.ABSI01000010_gene3476	2.911e-41	164.0	COG0407@1|root,COG5012@1|root,COG0407@2|Bacteria,COG5012@2|Bacteria,46V92@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
CH3_k127_1974226_0	1267535.KB906767_gene1403	4.035e-283	903.0	COG3408@1|root,COG3408@2|Bacteria,3Y2YG@57723|Acidobacteria	57723|Acidobacteria	G	Bacterial alpha-L-rhamnosidase C-terminal domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
CH3_k127_1974226_1	1328313.DS2_07733	2.018e-182	576.0	COG2407@1|root,COG2407@2|Bacteria,1R5ZQ@1224|Proteobacteria,1RNGR@1236|Gammaproteobacteria,469P5@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	L-fucose isomerase, C-terminal domain	-	-	5.3.1.4	ko:K01804	ko00040,ko01100,map00040,map01100	-	R01761	RC00516	ko00000,ko00001,ko01000	-	-	-	Arabinose_Isome,Fucose_iso_C
CH3_k127_197580_3	240016.ABIZ01000001_gene1044	1.798e-62	234.0	2F6YF@1|root,33ZEH@2|Bacteria,46VWD@74201|Verrucomicrobia,2IU9D@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_197580_4	452637.Oter_1164	3.069e-06	55.0	COG0501@1|root,COG4969@1|root,COG0501@2|Bacteria,COG4969@2|Bacteria	2|Bacteria	NU	cell adhesion	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Peptidase_M48,Pilin_GH
CH3_k127_197580_0	382464.ABSI01000021_gene382	1.191e-189	603.0	COG1524@1|root,COG1524@2|Bacteria,46UZ5@74201|Verrucomicrobia,2ITHB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
CH3_k127_197580_2	221288.JH992901_gene3829	8.05e-124	411.0	COG0337@1|root,COG0337@2|Bacteria,1G2JF@1117|Cyanobacteria	1117|Cyanobacteria	E	PFAM 3-dehydroquinate synthase	-	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
CH3_k127_197580_1	886293.Sinac_6122	1.283e-143	467.0	COG3391@1|root,COG3511@1|root,COG3391@2|Bacteria,COG3511@2|Bacteria,2IYNB@203682|Planctomycetes	203682|Planctomycetes	M	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase,Phosphoesterase
CH3_k127_2018513_0	234267.Acid_6855	2.957e-212	671.0	COG3119@1|root,COG3119@2|Bacteria,3Y7MP@57723|Acidobacteria	57723|Acidobacteria	P	PFAM Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CH3_k127_2018513_11	1396141.BATP01000019_gene1718	2.351e-12	78.0	COG3225@1|root,COG3225@2|Bacteria,46UZA@74201|Verrucomicrobia,2IUBV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	N	ABC-type uncharacterized transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
CH3_k127_2018513_10	1191523.MROS_2048	1.916e-21	109.0	COG0737@1|root,COG3303@1|root,COG0737@2|Bacteria,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	5_nucleotid_C,Cytochrom_C552,Cytochrome_C554,Paired_CXXCH_1,SBP_bac_8,SLH
CH3_k127_2018513_8	452637.Oter_2583	5.136e-88	299.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	omcI	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
CH3_k127_2018513_9	452637.Oter_0906	1.25e-46	179.0	COG0664@1|root,COG0664@2|Bacteria,46VK1@74201|Verrucomicrobia,3K7W4@414999|Opitutae	74201|Verrucomicrobia	K	Crp Fnr family	-	-	-	ko:K21563	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CH3_k127_2018513_5	382464.ABSI01000010_gene3644	7.281e-117	388.0	COG0407@1|root,COG0407@2|Bacteria,46X9N@74201|Verrucomicrobia,2IV4H@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
CH3_k127_2018513_1	583355.Caka_2769	1.418e-159	515.0	COG0635@1|root,COG0635@2|Bacteria,46TQX@74201|Verrucomicrobia,3K7DD@414999|Opitutae	414999|Opitutae	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
CH3_k127_2018513_12	391625.PPSIR1_12288	1.195e-07	60.0	COG4914@1|root,COG4914@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2204
CH3_k127_2018513_6	1379270.AUXF01000005_gene406	2.654e-112	379.0	COG1232@1|root,COG1232@2|Bacteria,1ZUZT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	-	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
CH3_k127_2018513_4	382464.ABSI01000005_gene1230	5.108e-117	385.0	COG0276@1|root,COG0276@2|Bacteria,46XCA@74201|Verrucomicrobia,2IVEM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Ferrochelatase	-	-	-	-	-	-	-	-	-	-	-	-	Ferrochelatase
CH3_k127_2018513_2	1550073.JROH01000032_gene1995	1.695e-122	408.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,2TSE2@28211|Alphaproteobacteria,2K21U@204457|Sphingomonadales	204457|Sphingomonadales	E	Glutamate synthase	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
CH3_k127_2018513_13	1123070.KB899250_gene635	0.0006183	48.0	COG1918@1|root,COG1918@2|Bacteria,46ZGK@74201|Verrucomicrobia,2IWG5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	FeoA domain	-	-	-	-	-	-	-	-	-	-	-	-	FeoA
CH3_k127_2018513_3	742725.HMPREF9450_01261	2.759e-120	401.0	COG2871@1|root,COG3894@1|root,COG2871@2|Bacteria,COG3894@2|Bacteria,4PAMG@976|Bacteroidetes,2FXAJ@200643|Bacteroidia	976|Bacteroidetes	C	Domain of unknown function (DUF4445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
CH3_k127_2024481_1	1192034.CAP_5178	6.635e-159	515.0	COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,42MDI@68525|delta/epsilon subdivisions,2WIVY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	malic protein domain protein	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
CH3_k127_2024481_7	517418.Ctha_2510	7.149e-30	127.0	COG3258@1|root,COG3258@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrome_CBB3,DUF3365
CH3_k127_2024481_5	382464.ABSI01000007_gene4118	1.57e-88	297.0	COG0745@1|root,COG0745@2|Bacteria,46TFB@74201|Verrucomicrobia,2IUEX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CH3_k127_2024481_4	240292.Ava_3452	7.099e-98	340.0	COG5002@1|root,COG5002@2|Bacteria,1GQDS@1117|Cyanobacteria,1HME7@1161|Nostocales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
CH3_k127_2024481_8	246197.MXAN_4314	7.142e-14	76.0	COG0607@1|root,COG0607@2|Bacteria,1MZPW@1224|Proteobacteria,42NX5@68525|delta/epsilon subdivisions,2WMJ4@28221|Deltaproteobacteria,2Z1G5@29|Myxococcales	28221|Deltaproteobacteria	P	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,Rubrerythrin
CH3_k127_2024481_3	497965.Cyan7822_5111	9.496e-153	491.0	COG0082@1|root,COG0082@2|Bacteria,1G12S@1117|Cyanobacteria,3KGGQ@43988|Cyanothece	1117|Cyanobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.aroC	Chorismate_synt
CH3_k127_2024481_2	1267535.KB906767_gene4768	5.387e-155	503.0	2DBP2@1|root,2ZA71@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_2024481_6	497964.CfE428DRAFT_3472	1.053e-41	162.0	COG1579@1|root,COG1579@2|Bacteria,46T10@74201|Verrucomicrobia	74201|Verrucomicrobia	S	C4-type zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
CH3_k127_2024481_9	314264.ROS217_14991	1.566e-09	64.0	2ENFV@1|root,33G39@2|Bacteria,1NP5K@1224|Proteobacteria,2UJUH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_2024481_0	317936.Nos7107_4863	4.473e-177	568.0	COG1649@1|root,COG1649@2|Bacteria,1G42C@1117|Cyanobacteria,1HQTX@1161|Nostocales	1117|Cyanobacteria	S	Glycosyl hydrolase-like 10	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
CH3_k127_2041730_22	370438.PTH_1110	5.491e-33	143.0	COG1388@1|root,COG1388@2|Bacteria,1VJ2T@1239|Firmicutes,24YEF@186801|Clostridia,264FH@186807|Peptococcaceae	186801|Clostridia	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_2041730_7	1454007.JAUG01000047_gene512	1.173e-167	539.0	COG0673@1|root,COG0673@2|Bacteria,4NJ92@976|Bacteroidetes,1ISF7@117747|Sphingobacteriia	976|Bacteroidetes	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CH3_k127_2041730_24	1395587.P364_0117575	2.164e-25	114.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,4HC17@91061|Bacilli,26TDT@186822|Paenibacillaceae	91061|Bacilli	K	Belongs to the sigma-70 factor family. ECF subfamily	sigW	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CH3_k127_2041730_15	240016.ABIZ01000001_gene1086	2.043e-89	300.0	COG0605@1|root,COG0605@2|Bacteria,46SQF@74201|Verrucomicrobia,2IU40@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Iron/manganese superoxide dismutases, alpha-hairpin domain	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
CH3_k127_2041730_13	382464.ABSI01000011_gene2675	8.562e-116	391.0	COG2610@1|root,COG2610@2|Bacteria,46UQS@74201|Verrucomicrobia,2IVYC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EG	GntP family permease	-	-	-	-	-	-	-	-	-	-	-	-	GntP_permease
CH3_k127_2041730_19	1123508.JH636439_gene1058	2.679e-49	184.0	COG4221@1|root,COG4221@2|Bacteria,2IYVR@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CH3_k127_2041730_5	497964.CfE428DRAFT_0139	3.002e-176	557.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CH3_k127_2041730_0	1123242.JH636434_gene3346	0.0	1187.0	COG2010@1|root,COG2010@2|Bacteria,2IXJ6@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
CH3_k127_2041730_3	1396418.BATQ01000142_gene3267	9.277e-219	687.0	COG3119@1|root,COG3119@2|Bacteria,46Z2W@74201|Verrucomicrobia,2IWNY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CH3_k127_2041730_20	269482.Bcep1808_5363	4.941e-47	173.0	COG0454@1|root,COG0456@2|Bacteria,1QTYD@1224|Proteobacteria,2WGHN@28216|Betaproteobacteria,1K7F9@119060|Burkholderiaceae	28216|Betaproteobacteria	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7
CH3_k127_2041730_17	1403819.BATR01000017_gene538	6.737e-57	202.0	COG1764@1|root,COG1764@2|Bacteria,46VXJ@74201|Verrucomicrobia,2IW5Z@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
CH3_k127_2041730_18	1123508.JH636443_gene5018	2.819e-51	187.0	COG3324@1|root,COG3324@2|Bacteria,2J3W8@203682|Planctomycetes	203682|Planctomycetes	S	Glyoxalase-like domain	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	-
CH3_k127_2041730_23	1396141.BATP01000059_gene2546	8.142e-28	118.0	2CIV9@1|root,34A52@2|Bacteria,46W0H@74201|Verrucomicrobia,2IUYN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Control of competence regulator ComK, YlbF/YmcA	-	-	-	-	-	-	-	-	-	-	-	-	Com_YlbF
CH3_k127_2041730_4	1403819.BATR01000191_gene6501	1.497e-211	668.0	COG3119@1|root,COG3119@2|Bacteria,46S9C@74201|Verrucomicrobia,2ITNC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Domain of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	DUF4994,Sulfatase
CH3_k127_2041730_9	1122605.KB893648_gene3690	5.85e-150	498.0	28J61@1|root,2Z91S@2|Bacteria,4NKJU@976|Bacteroidetes	976|Bacteroidetes	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_129
CH3_k127_2041730_1	1123248.KB893318_gene4130	2.168e-311	992.0	COG3250@1|root,COG3250@2|Bacteria,4NFE8@976|Bacteroidetes,1IUSY@117747|Sphingobacteriia	976|Bacteroidetes	G	family 2 sugar binding	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106,Glyco_hydro_2_N
CH3_k127_2041730_12	414684.RC1_3258	1.114e-121	398.0	COG2070@1|root,COG2070@2|Bacteria,1MU0U@1224|Proteobacteria,2TS5U@28211|Alphaproteobacteria,2JQFB@204441|Rhodospirillales	204441|Rhodospirillales	S	Nitronate monooxygenase	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
CH3_k127_2041730_2	661478.OP10G_0590	1.407e-273	884.0	COG3940@1|root,COG3940@2|Bacteria	2|Bacteria	G	arabinan catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106,Glyco_hydro_2_N,Glyco_hydro_43,Laminin_G_3
CH3_k127_2041730_10	1177154.Y5S_00716	3.552e-141	465.0	COG0591@1|root,COG0591@2|Bacteria,1QUXM@1224|Proteobacteria,1T251@1236|Gammaproteobacteria,1XJTT@135619|Oceanospirillales	135619|Oceanospirillales	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
CH3_k127_2041730_11	1499967.BAYZ01000089_gene5014	1.293e-137	457.0	COG0043@1|root,COG0043@2|Bacteria	2|Bacteria	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity	ubiD	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
CH3_k127_2041730_21	265072.Mfla_2506	1.064e-46	188.0	COG0537@1|root,COG0537@2|Bacteria,1MZVD@1224|Proteobacteria,2VU7S@28216|Betaproteobacteria,2KMRM@206350|Nitrosomonadales	206350|Nitrosomonadales	FG	PFAM histidine triad (HIT) protein	-	-	-	-	-	-	-	-	-	-	-	-	HIT
CH3_k127_2041730_16	1499967.BAYZ01000089_gene5015	3.356e-82	280.0	COG1212@1|root,COG1212@2|Bacteria,2NP8R@2323|unclassified Bacteria	2|Bacteria	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
CH3_k127_2041730_14	1123242.JH636434_gene4153	3.357e-113	377.0	COG4409@1|root,COG4409@2|Bacteria,2J53Z@203682|Planctomycetes	203682|Planctomycetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
CH3_k127_2041730_6	1499967.BAYZ01000095_gene4068	9.007e-168	536.0	COG0407@1|root,COG0407@2|Bacteria,2NRD5@2323|unclassified Bacteria	2|Bacteria	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
CH3_k127_2041730_8	1396141.BATP01000040_gene2191	5.916e-162	513.0	COG0673@1|root,COG0673@2|Bacteria,46U95@74201|Verrucomicrobia,2IVCR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CH3_k127_2047217_1	759914.BP951000_1517	7.636e-25	123.0	COG0457@1|root,COG0457@2|Bacteria	759914.BP951000_1517|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_2047217_3	497964.CfE428DRAFT_3571	1.567e-15	84.0	COG1595@1|root,COG1595@2|Bacteria,46VJX@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CH3_k127_2047217_0	497964.CfE428DRAFT_5038	1.574e-110	370.0	COG1520@1|root,COG1520@2|Bacteria,46T0C@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM Pyrrolo-quinoline quinone	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
CH3_k127_2047217_2	1396141.BATP01000062_gene4448	7.825e-23	106.0	COG2939@1|root,COG2939@2|Bacteria,46UB7@74201|Verrucomicrobia,2IVCV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Serine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
CH3_k127_2047217_4	720554.Clocl_3888	2.869e-07	55.0	COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,24FQX@186801|Clostridia,3WIIZ@541000|Ruminococcaceae	186801|Clostridia	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
CH3_k127_2048810_2	1121012.AUKX01000016_gene3000	4.577e-96	329.0	28K60@1|root,2Z9UH@2|Bacteria,4NHE6@976|Bacteroidetes,1HYIC@117743|Flavobacteriia	976|Bacteroidetes	S	Methane oxygenase PmoA	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
CH3_k127_2048810_0	1121012.AUKX01000016_gene3001	1.857e-179	574.0	COG0673@1|root,COG0673@2|Bacteria,4NGTW@976|Bacteroidetes,1I164@117743|Flavobacteriia,23IAD@178469|Arenibacter	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CH3_k127_2048810_3	485917.Phep_3119	2.156e-65	234.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,4NG20@976|Bacteroidetes,1J03Z@117747|Sphingobacteriia	976|Bacteroidetes	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
CH3_k127_2048810_1	1396141.BATP01000028_gene2285	1.578e-99	363.0	COG4412@1|root,COG5306@1|root,COG4412@2|Bacteria,COG5306@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	ko:K07004,ko:K09955,ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	Big_4,F5_F8_type_C,Laminin_G_3
CH3_k127_2106740_1	1123508.JH636441_gene3735	2.449e-67	247.0	28IKQ@1|root,2Z8MC@2|Bacteria,2IXYY@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane
CH3_k127_2106740_0	886293.Sinac_0926	1.363e-212	671.0	COG3119@1|root,COG3119@2|Bacteria,2IXG7@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
CH3_k127_2106740_3	452637.Oter_1161	9.695e-14	80.0	COG4575@1|root,COG4575@2|Bacteria,46WFC@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Bacterial protein of unknown function (DUF883)	-	-	-	-	-	-	-	-	-	-	-	-	DUF883
CH3_k127_2106740_4	278957.ABEA03000005_gene4419	3.617e-10	65.0	COG5393@1|root,COG5393@2|Bacteria,46XW8@74201|Verrucomicrobia,3K8G8@414999|Opitutae	414999|Opitutae	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
CH3_k127_2106740_2	382464.ABSI01000013_gene1799	4.906e-42	158.0	COG2239@1|root,COG2239@2|Bacteria,46S6D@74201|Verrucomicrobia,2IU82@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Divalent cation transporter	-	-	-	-	-	-	-	-	-	-	-	-	CBS,MgtE,MgtE_N
CH3_k127_2124611_0	204669.Acid345_0011	3.979e-162	524.0	COG5316@1|root,COG5316@2|Bacteria,3Y4FP@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139
CH3_k127_2124611_8	237368.SCABRO_03057	2.255e-77	275.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1
CH3_k127_2124611_17	1123508.JH636439_gene1468	3.981e-23	114.0	COG0515@1|root,COG3642@1|root,COG0515@2|Bacteria,COG3642@2|Bacteria,2IZTN@203682|Planctomycetes	203682|Planctomycetes	KLT	Lipopolysaccharide kinase (Kdo/WaaP) family	-	-	-	-	-	-	-	-	-	-	-	-	Kdo
CH3_k127_2124611_10	497964.CfE428DRAFT_3065	1.132e-71	250.0	2F2JH@1|root,33VGF@2|Bacteria	2|Bacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
CH3_k127_2124611_7	335543.Sfum_3152	1.661e-80	275.0	COG0500@1|root,COG2226@2|Bacteria,1NGTM@1224|Proteobacteria	1224|Proteobacteria	Q	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CH3_k127_2124611_11	880072.Desac_2043	2.226e-71	256.0	COG0438@1|root,COG0438@2|Bacteria,1NE3V@1224|Proteobacteria,42P4A@68525|delta/epsilon subdivisions,2WPG9@28221|Deltaproteobacteria,2MRJ3@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	PFAM Glycosyl transferase, group 1	-	-	-	ko:K02844	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
CH3_k127_2124611_20	1167006.UWK_02438	1.154e-05	57.0	COG3173@1|root,COG3173@2|Bacteria	2|Bacteria	S	very-long-chain-acyl-CoA dehydrogenase activity	-	-	2.7.1.119	ko:K17880	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	APH,EcKinase,HMG-CoA_red
CH3_k127_2124611_13	402881.Plav_1911	5.442e-57	215.0	COG0742@1|root,COG0742@2|Bacteria	2|Bacteria	L	rRNA (guanine-N2-)-methyltransferase activity	-	-	-	ko:K15257	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Cons_hypoth95,SAM_MT
CH3_k127_2124611_19	756067.MicvaDRAFT_4986	1.55e-10	73.0	COG2755@1|root,COG2755@2|Bacteria,1G060@1117|Cyanobacteria,1H9JP@1150|Oscillatoriales	1117|Cyanobacteria	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL
CH3_k127_2124611_6	926549.KI421517_gene437	5.156e-84	285.0	COG4122@1|root,COG4122@2|Bacteria	2|Bacteria	E	O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21,SAM_MT
CH3_k127_2124611_15	1485545.JQLW01000005_gene1063	6.431e-43	166.0	COG2227@1|root,COG2227@2|Bacteria,1QY24@1224|Proteobacteria	1224|Proteobacteria	H	Pfam Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
CH3_k127_2124611_12	690850.Desaf_0021	1.634e-61	227.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,42R6N@68525|delta/epsilon subdivisions,2WP3W@28221|Deltaproteobacteria,2MG43@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CH3_k127_2124611_5	690850.Desaf_0024	2.543e-86	293.0	COG0463@1|root,COG0463@2|Bacteria,1PVP4@1224|Proteobacteria,42M23@68525|delta/epsilon subdivisions,2WNU9@28221|Deltaproteobacteria,2MHBU@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CH3_k127_2124611_4	401526.TcarDRAFT_0104	5.397e-102	357.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H20M@909932|Negativicutes	909932|Negativicutes	V	lipid A export permease ATP-binding protein MsbA	msbA	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
CH3_k127_2124611_18	497964.CfE428DRAFT_2605	1.839e-21	96.0	2E99J@1|root,333HQ@2|Bacteria,46T77@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4032
CH3_k127_2124611_14	1521187.JPIM01000042_gene1869	5.637e-56	202.0	COG2065@1|root,COG2065@2|Bacteria,2G6WS@200795|Chloroflexi,375J4@32061|Chloroflexia	32061|Chloroflexia	F	Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
CH3_k127_2124611_1	497964.CfE428DRAFT_2607	3.1e-133	431.0	COG0540@1|root,COG0540@2|Bacteria,46S9E@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
CH3_k127_2124611_3	497964.CfE428DRAFT_3356	3.103e-118	399.0	COG0700@1|root,COG2715@1|root,COG0700@2|Bacteria,COG2715@2|Bacteria,46TMH@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Nucleoside recognition	-	-	-	-	-	-	-	-	-	-	-	-	Gate
CH3_k127_2124611_16	1047013.AQSP01000114_gene693	6.43e-28	119.0	2E74N@1|root,331P2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_2124611_9	1123242.JH636434_gene5340	3.476e-76	280.0	COG1413@1|root,COG1413@2|Bacteria,2IZE1@203682|Planctomycetes	203682|Planctomycetes	C	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
CH3_k127_2124611_2	344747.PM8797T_11556	9.605e-121	402.0	COG0673@1|root,COG0673@2|Bacteria,2IXA3@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CH3_k127_2127189_5	697281.Mahau_2019	1.002e-16	90.0	COG1073@1|root,COG1073@2|Bacteria,1TTC0@1239|Firmicutes,24JPV@186801|Clostridia	186801|Clostridia	S	Prolyl oligopeptidase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4,Peptidase_S9
CH3_k127_2127189_0	246196.MSMEI_5805	3.166e-154	501.0	2DQMZ@1|root,337PX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_2127189_3	1403819.BATR01000125_gene4449	3.099e-22	102.0	2CEMG@1|root,346QA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
CH3_k127_2127189_2	240016.ABIZ01000001_gene2992	3.804e-35	155.0	2CEMG@1|root,346QA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
CH3_k127_2127189_1	525904.Tter_1998	2.077e-52	211.0	COG2730@1|root,COG2730@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	BACON,CW_binding_1,Cellulase,Collagen_bind_2,DUF4038,DUF5060
CH3_k127_2127189_4	313628.LNTAR_01300	8.859e-22	99.0	COG3507@1|root,COG3507@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
CH3_k127_2140306_9	1121441.AUCX01000018_gene1481	2.529e-17	83.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,42TRU@68525|delta/epsilon subdivisions,2WPZK@28221|Deltaproteobacteria,2MCF7@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
CH3_k127_2140306_10	754252.PFREUD_06030	3.528e-12	67.0	COG0257@1|root,COG0257@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
CH3_k127_2140306_7	497964.CfE428DRAFT_0508	1.171e-50	182.0	COG0099@1|root,COG0099@2|Bacteria,46STA@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
CH3_k127_2140306_6	497964.CfE428DRAFT_0509	2.446e-55	199.0	COG0100@1|root,COG0100@2|Bacteria,46STW@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
CH3_k127_2140306_5	278957.ABEA03000041_gene2061	1.713e-77	265.0	COG0522@1|root,COG0522@2|Bacteria,46SNI@74201|Verrucomicrobia,3K7K0@414999|Opitutae	414999|Opitutae	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
CH3_k127_2140306_1	1396141.BATP01000018_gene1517	2.303e-146	470.0	COG0202@1|root,COG0202@2|Bacteria,46S52@74201|Verrucomicrobia,2ITN6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
CH3_k127_2140306_8	1156937.MFUM_1030013	1.676e-30	127.0	COG0203@1|root,COG0203@2|Bacteria,46TC9@74201|Verrucomicrobia,37GVV@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
CH3_k127_2140306_2	886293.Sinac_5304	6.803e-108	370.0	COG0477@1|root,COG2814@2|Bacteria,2IY3A@203682|Planctomycetes	203682|Planctomycetes	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
CH3_k127_2140306_4	497964.CfE428DRAFT_2876	7.003e-90	301.0	COG2818@1|root,COG2818@2|Bacteria,46SS9@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Methyladenine glycosylase	-	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
CH3_k127_2140306_0	497964.CfE428DRAFT_4132	2.866e-177	567.0	COG1520@1|root,COG1520@2|Bacteria,46UCM@74201|Verrucomicrobia	2|Bacteria	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CH3_k127_2140306_3	452637.Oter_1003	5.87e-94	316.0	COG4299@1|root,COG4299@2|Bacteria,46S60@74201|Verrucomicrobia	74201|Verrucomicrobia	S	COGs COG4299 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624,DUF5009
CH3_k127_2152085_8	1056820.KB900700_gene1152	5.111e-19	93.0	COG2968@1|root,COG2968@2|Bacteria,1RC2K@1224|Proteobacteria,1S244@1236|Gammaproteobacteria,2PQ3U@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	S	Protein of unknown function (DUF541)	-	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
CH3_k127_2152085_7	497964.CfE428DRAFT_4941	2.012e-22	101.0	2E5PI@1|root,330E7@2|Bacteria,46W49@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_2152085_1	497964.CfE428DRAFT_4940	7.955e-137	440.0	COG1099@1|root,COG1099@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	ko:K07051	-	-	-	-	ko00000	-	-	-	TatD_DNase
CH3_k127_2152085_3	452637.Oter_1808	9.2e-84	290.0	COG2378@1|root,COG2378@2|Bacteria,46VG3@74201|Verrucomicrobia,3K846@414999|Opitutae	414999|Opitutae	K	WYL domain	-	-	-	ko:K13572	-	-	-	-	ko00000,ko03051	-	-	-	WYL
CH3_k127_2152085_4	452637.Oter_1864	3.602e-54	199.0	COG3327@1|root,COG3327@2|Bacteria,46W9G@74201|Verrucomicrobia	74201|Verrucomicrobia	K	negative regulation of DNA-templated transcription, initiation	-	-	-	ko:K02616	-	-	-	-	ko00000,ko03000	-	-	-	PaaX_C
CH3_k127_2152085_6	452637.Oter_2367	2.665e-36	145.0	2E5IJ@1|root,3309Y@2|Bacteria,46SYV@74201|Verrucomicrobia,3K87A@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_2152085_0	497964.CfE428DRAFT_0348	1.093e-236	759.0	COG0612@1|root,COG0612@2|Bacteria,46S9I@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM peptidase M16 domain protein	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
CH3_k127_2152085_9	309801.trd_A0913	2.689e-17	87.0	COG4911@1|root,COG4911@2|Bacteria,2G7A8@200795|Chloroflexi,27YIV@189775|Thermomicrobia	189775|Thermomicrobia	S	Uncharacterized conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
CH3_k127_2152085_5	497964.CfE428DRAFT_5668	3.796e-46	188.0	COG0457@1|root,COG0457@2|Bacteria,46V4J@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_8
CH3_k127_2152085_2	497964.CfE428DRAFT_5666	3.961e-118	389.0	COG0040@1|root,COG0040@2|Bacteria,46SHK@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Histidine biosynthesis protein HisG domain	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
CH3_k127_2152085_10	1161401.ASJA01000019_gene1136	4.451e-11	64.0	COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,2TRY6@28211|Alphaproteobacteria,43XDA@69657|Hyphomonadaceae	28211|Alphaproteobacteria	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	GO:0003674,GO:0003824,GO:0004644,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N,YjbR
CH3_k127_2167433_0	1123242.JH636434_gene5260	1.596e-270	857.0	COG4654@1|root,COG4654@2|Bacteria,2J54P@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
CH3_k127_2167433_1	1123242.JH636434_gene5259	1.579e-225	706.0	COG3119@1|root,COG3119@2|Bacteria,2IX9P@203682|Planctomycetes	203682|Planctomycetes	P	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CH3_k127_2167433_3	641524.ADICYQ_2511	5.798e-148	482.0	2DBQR@1|root,2ZAG2@2|Bacteria,4NK84@976|Bacteroidetes,47NS0@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2
CH3_k127_2167433_2	1396418.BATQ01000117_gene4594	6.274e-178	563.0	2DBKQ@1|root,2Z9U7@2|Bacteria,46XD4@74201|Verrucomicrobia,2IVHS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_2172902_3	94624.Bpet4290	7.761e-16	78.0	COG1403@1|root,COG3344@1|root,COG1403@2|Bacteria,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,2VKHY@28216|Betaproteobacteria,3T90F@506|Alcaligenaceae	28216|Betaproteobacteria	LV	Retron-type reverse transcriptase	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,HNH,RVT_1,RVT_N
CH3_k127_2172902_4	1235803.C825_03137	1.646e-07	54.0	COG3547@1|root,COG3547@2|Bacteria,4PB8R@976|Bacteroidetes,2FYNJ@200643|Bacteroidia	976|Bacteroidetes	L	Transposase (IS116 IS110 IS902 family)	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_2172902_2	1122919.KB905557_gene1198	3.243e-17	87.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,4HB31@91061|Bacilli,26QK1@186822|Paenibacillaceae	91061|Bacilli	E	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
CH3_k127_2172902_1	452637.Oter_2699	5.549e-37	145.0	COG4430@1|root,COG4430@2|Bacteria,46WQC@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
CH3_k127_2172902_5	983544.Lacal_2171	0.0002344	52.0	COG3797@1|root,COG3797@2|Bacteria,4NSKS@976|Bacteroidetes,1I70K@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
CH3_k127_2172902_0	404589.Anae109_2915	6.706e-59	210.0	COG2010@1|root,COG2010@2|Bacteria,1RBTK@1224|Proteobacteria,43AHK@68525|delta/epsilon subdivisions,2X5XT@28221|Deltaproteobacteria,2YVZ8@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_2196710_5	936154.STP_1609	0.0007783	46.0	COG1396@1|root,COG2932@1|root,COG1396@2|Bacteria,COG2932@2|Bacteria,1VDKY@1239|Firmicutes,4IS6B@91061|Bacilli	91061|Bacilli	K	Peptidase S24-like	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,Peptidase_S24
CH3_k127_2196710_1	1379698.RBG1_1C00001G1377	1.445e-34	151.0	COG4409@1|root,COG4409@2|Bacteria,2NRD7@2323|unclassified Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,BNR_2,Big_3_2,CBM_35,DUF1080,F5_F8_type_C,PKD,RicinB_lectin_2,Trehalase
CH3_k127_2196710_3	794903.OPIT5_05990	2.998e-18	94.0	COG2165@1|root,COG2165@2|Bacteria,46YG4@74201|Verrucomicrobia,3K9HT@414999|Opitutae	414999|Opitutae	NU	Protein of unknown function (DUF1559)	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CH3_k127_2196710_0	867845.KI911784_gene1260	2.197e-64	254.0	COG0823@1|root,COG1520@1|root,COG0823@2|Bacteria,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	ko:K03641,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.C.1.2	-	-	DUF11,HYR,PD40,PQQ_2,VCBS
CH3_k127_2196710_4	1121896.JMLU01000001_gene1198	2.332e-14	89.0	COG2356@1|root,COG2356@2|Bacteria,4PNZR@976|Bacteroidetes	976|Bacteroidetes	L	endonuclease I	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9
CH3_k127_2196710_2	497964.CfE428DRAFT_4009	5.083e-24	105.0	2EG51@1|root,339WY@2|Bacteria,46WHK@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_2222394_0	7668.SPU_001163-tr	2.097e-53	210.0	COG0666@1|root,KOG0504@2759|Eukaryota,KOG4177@2759|Eukaryota,38BVK@33154|Opisthokonta,3BGGV@33208|Metazoa,3CT1S@33213|Bilateria	33208|Metazoa	M	ankyrin 3, node of Ranvier (ankyrin G)	-	-	-	-	-	-	-	-	-	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5,ZU5
CH3_k127_2222394_2	583355.Caka_1010	7.597e-06	60.0	COG0790@1|root,COG4775@1|root,COG0790@2|Bacteria,COG4775@2|Bacteria,46W4W@74201|Verrucomicrobia,3K9YE@414999|Opitutae	414999|Opitutae	M	Sel1 domain protein repeat-containing protein	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
CH3_k127_2222394_1	481448.Minf_0292	2.404e-39	171.0	COG0760@1|root,COG0760@2|Bacteria,46SU4@74201|Verrucomicrobia,37G1D@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
CH3_k127_2237344_4	679200.HMPREF9333_00914	1.755e-06	60.0	COG1277@1|root,COG1277@2|Bacteria,1V90F@1239|Firmicutes,25DFP@186801|Clostridia	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2,ABC2_membrane_3
CH3_k127_2237344_1	1210884.HG799473_gene15021	1.318e-184	586.0	2BXG3@1|root,2Z82R@2|Bacteria,2IXSD@203682|Planctomycetes	203682|Planctomycetes	S	tagaturonate epimerase	-	-	5.1.2.7	ko:K21619	ko00040,ko01100,map00040,map01100	-	R11624	-	ko00000,ko00001,ko01000	-	-	-	UxaE
CH3_k127_2237344_0	234267.Acid_7084	1.308e-207	648.0	COG0524@1|root,COG0524@2|Bacteria,3Y3DE@57723|Acidobacteria	57723|Acidobacteria	G	PfkB domain protein	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
CH3_k127_2237344_3	395495.Lcho_4142	1.445e-06	51.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,2VHUC@28216|Betaproteobacteria,1KK1H@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
CH3_k127_2237344_2	1248916.ANFY01000003_gene505	2.039e-16	89.0	2919Q@1|root,331DT@2|Bacteria,1RD8H@1224|Proteobacteria,2U8WH@28211|Alphaproteobacteria,2K49X@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_2308899_12	65093.PCC7418_1588	4.193e-55	201.0	2EWKK@1|root,33PYP@2|Bacteria,1GC1A@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_2308899_3	1173263.Syn7502_02619	6.382e-126	413.0	COG2189@1|root,COG2189@2|Bacteria,1G2XK@1117|Cyanobacteria,1H2TB@1129|Synechococcus	1117|Cyanobacteria	H	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
CH3_k127_2308899_8	1198232.CYCME_1216	3.496e-74	255.0	COG1715@1|root,COG1715@2|Bacteria,1R2JZ@1224|Proteobacteria,1T5RK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	Restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_2308899_13	215803.DB30_8826	2.985e-29	124.0	28H95@1|root,2Z7KY@2|Bacteria,1RA0C@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF4256)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4256
CH3_k127_2308899_11	272123.Anacy_0345	2.378e-59	213.0	COG5483@1|root,COG5483@2|Bacteria,1G5J1@1117|Cyanobacteria,1HP7V@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
CH3_k127_2308899_9	1121004.ATVC01000068_gene1663	2.528e-61	217.0	COG5483@1|root,COG5483@2|Bacteria,1RDGV@1224|Proteobacteria,2VV76@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
CH3_k127_2308899_14	1121004.ATVC01000068_gene1664	8.57e-18	94.0	2DQR1@1|root,32UPK@2|Bacteria,1NKZE@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_2308899_6	765911.Thivi_0930	6.975e-85	289.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RNUJ@1236|Gammaproteobacteria,1WXIC@135613|Chromatiales	135613|Chromatiales	V	PFAM ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CH3_k127_2308899_7	580332.Slit_2080	6.521e-75	272.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,2VJR5@28216|Betaproteobacteria,44V3R@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
CH3_k127_2308899_2	497964.CfE428DRAFT_5498	2.613e-145	474.0	COG0520@1|root,COG0520@2|Bacteria	2|Bacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	cefD	-	5.1.1.17	ko:K04127,ko:K11325,ko:K21174	ko00311,ko01059,ko01100,ko01130,map00311,map01059,map01100,map01130	M00673,M00825	R04147	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
CH3_k127_2308899_10	485918.Cpin_3102	7.42e-60	214.0	COG2197@1|root,COG2197@2|Bacteria,4NHTM@976|Bacteroidetes,1ITQW@117747|Sphingobacteriia	976|Bacteroidetes	T	COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CH3_k127_2308899_1	1396141.BATP01000029_gene2231	2.774e-159	542.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
CH3_k127_2308899_4	521674.Plim_1708	7.091e-114	381.0	COG1793@1|root,COG1793@2|Bacteria,2J0I2@203682|Planctomycetes	203682|Planctomycetes	L	secreted glycosyl hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CH3_k127_2308899_5	497964.CfE428DRAFT_0981	3.417e-106	354.0	COG2133@1|root,COG2133@2|Bacteria,46V3J@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Methane oxygenase PmoA	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
CH3_k127_2308899_0	240016.ABIZ01000001_gene5946	5.868e-175	561.0	COG0673@1|root,COG0673@2|Bacteria,46U0A@74201|Verrucomicrobia,2IWJK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CH3_k127_2308899_15	335543.Sfum_0069	6.835e-14	84.0	COG1357@1|root,COG2201@1|root,COG1357@2|Bacteria,COG2201@2|Bacteria	2|Bacteria	NT	protein-glutamate methylesterase activity	cheB	GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0097159,GO:1901363	3.1.1.61,3.5.1.44	ko:K03412,ko:K03413,ko:K18876	ko02020,ko02030,ko04626,map02020,map02030,map04626	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,DDE_5,Response_reg,TAL_effector
CH3_k127_2308899_17	706587.Desti_1174	1.581e-06	60.0	COG2204@1|root,COG2204@2|Bacteria,1RKC4@1224|Proteobacteria,42SJ3@68525|delta/epsilon subdivisions,2WPI1@28221|Deltaproteobacteria,2MRU7@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CH3_k127_2308899_16	378806.STAUR_0706	1.051e-09	70.0	COG1716@1|root,COG3829@1|root,COG1716@2|Bacteria,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,43BKG@68525|delta/epsilon subdivisions,2X7B6@28221|Deltaproteobacteria,2YUAZ@29|Myxococcales	28221|Deltaproteobacteria	K	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	ko:K07715	ko02020,ko02024,map02020,map02024	M00502	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	FHA,HTH_8,Sigma54_activat,Yop-YscD_cpl
CH3_k127_2339759_0	1232437.KL661961_gene3005	1.606e-71	249.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,42MB9@68525|delta/epsilon subdivisions,2WJ64@28221|Deltaproteobacteria,2MJ4H@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	Short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CH3_k127_2339759_2	1054213.HMPREF9946_02237	2.376e-33	137.0	COG3056@1|root,COG3056@2|Bacteria,1NKTA@1224|Proteobacteria,2UT4N@28211|Alphaproteobacteria,2JX6F@204441|Rhodospirillales	204441|Rhodospirillales	M	Uncharacterized lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_16
CH3_k127_2339759_1	1123242.JH636434_gene4140	2.543e-71	242.0	COG0057@1|root,COG0057@2|Bacteria,2IX66@203682|Planctomycetes	203682|Planctomycetes	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
CH3_k127_2348496_2	700598.Niako_3627	1.814e-94	316.0	COG0697@1|root,2Z7ID@2|Bacteria,4NEHB@976|Bacteroidetes,1IVNN@117747|Sphingobacteriia	976|Bacteroidetes	EG	L-rhamnose-proton symport protein (RhaT)	rhaT	-	-	ko:K02856	-	-	-	-	ko00000,ko02000	2.A.7.6	-	-	RhaT
CH3_k127_2348496_0	313628.LNTAR_22814	3.869e-302	953.0	COG1554@1|root,COG1554@2|Bacteria	2|Bacteria	G	hydrolase, family 65, central catalytic	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hyd_65N_2,Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m
CH3_k127_2348496_1	1454007.JAUG01000073_gene4094	2.053e-167	549.0	COG2247@1|root,COG2247@2|Bacteria,4P17J@976|Bacteroidetes	976|Bacteroidetes	M	cell wall binding repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF5013
CH3_k127_2348496_3	869213.JCM21142_3780	2.048e-32	136.0	COG3533@1|root,COG3533@2|Bacteria,4NFW3@976|Bacteroidetes,47M6F@768503|Cytophagia	976|Bacteroidetes	S	Beta-L-arabinofuranosidase, GH127	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
CH3_k127_2360834_3	452637.Oter_1883	3.457e-29	121.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
CH3_k127_2360834_0	472759.Nhal_2032	2.697e-159	516.0	COG0464@1|root,COG0464@2|Bacteria,1MW4T@1224|Proteobacteria,1RPUI@1236|Gammaproteobacteria,1WXBQ@135613|Chromatiales	135613|Chromatiales	O	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
CH3_k127_2360834_2	504472.Slin_1223	3.003e-109	362.0	COG2755@1|root,COG2755@2|Bacteria,4NIBN@976|Bacteroidetes,47NY7@768503|Cytophagia	976|Bacteroidetes	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CH3_k127_2360834_1	1254432.SCE1572_30435	2.594e-121	397.0	COG0274@1|root,COG0274@2|Bacteria,1N8AG@1224|Proteobacteria,42S16@68525|delta/epsilon subdivisions,2WNEY@28221|Deltaproteobacteria,2YYRJ@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
CH3_k127_2360834_4	794903.OPIT5_30270	1.414e-22	107.0	COG2259@1|root,COG2259@2|Bacteria	2|Bacteria	S	methylamine metabolic process	mauE	-	-	-	-	-	-	-	-	-	-	-	DoxX,MauE
CH3_k127_2360834_5	1232437.KL662027_gene2817	6.098e-08	57.0	COG0607@1|root,COG0607@2|Bacteria,1N256@1224|Proteobacteria,42TIJ@68525|delta/epsilon subdivisions,2WQGJ@28221|Deltaproteobacteria,2MKF4@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CH3_k127_2384565_9	96561.Dole_2050	1.301e-06	51.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,42Q3J@68525|delta/epsilon subdivisions,2WP5U@28221|Deltaproteobacteria,2MKDQ@213118|Desulfobacterales	28221|Deltaproteobacteria	M	TIGRFAM YD repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat,YwqJ-deaminase
CH3_k127_2384565_3	313628.LNTAR_11026	4.405e-94	323.0	COG3464@1|root,COG3464@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
CH3_k127_2384565_2	497964.CfE428DRAFT_4495	2.864e-110	365.0	COG0356@1|root,COG0356@2|Bacteria,46SVZ@74201|Verrucomicrobia	74201|Verrucomicrobia	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
CH3_k127_2384565_7	497964.CfE428DRAFT_4494	5.125e-18	93.0	2DS8G@1|root,33EZT@2|Bacteria,46T9M@74201|Verrucomicrobia	74201|Verrucomicrobia	S	ATP synthase subunit C	-	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
CH3_k127_2384565_5	497964.CfE428DRAFT_4493	1.721e-43	164.0	COG0711@1|root,COG0711@2|Bacteria,46SYI@74201|Verrucomicrobia	74201|Verrucomicrobia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
CH3_k127_2384565_6	1403819.BATR01000049_gene1414	3.351e-27	116.0	COG0712@1|root,COG0712@2|Bacteria,46TC4@74201|Verrucomicrobia,2IUUI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	ATP synthase delta (OSCP) subunit	-	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
CH3_k127_2384565_0	497964.CfE428DRAFT_4491	1.55e-251	783.0	COG0056@1|root,COG0056@2|Bacteria,46SB5@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
CH3_k127_2384565_4	497964.CfE428DRAFT_4490	2.464e-91	308.0	COG0224@1|root,COG0224@2|Bacteria,46SGU@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
CH3_k127_2384565_1	1396141.BATP01000030_gene3796	8.823e-224	703.0	COG0055@1|root,COG0055@2|Bacteria,46SCC@74201|Verrucomicrobia,2IU0R@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
CH3_k127_2384565_8	643562.Daes_3108	8.17e-08	54.0	COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,42TII@68525|delta/epsilon subdivisions,2WPVK@28221|Deltaproteobacteria,2MBW9@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
CH3_k127_244319_6	452637.Oter_1439	3.359e-05	51.0	COG1544@1|root,COG1544@2|Bacteria,46WN8@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Sigma 54 modulation protein / S30EA ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_S30AE
CH3_k127_244319_0	402777.KB235903_gene2363	2.628e-81	295.0	COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,1G1Z8@1117|Cyanobacteria,1H950@1150|Oscillatoriales	1117|Cyanobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4
CH3_k127_244319_2	497964.CfE428DRAFT_6232	3.201e-33	133.0	COG0745@1|root,COG0745@2|Bacteria,46W19@74201|Verrucomicrobia	74201|Verrucomicrobia	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CH3_k127_244319_1	1469607.KK073768_gene1804	6.527e-57	209.0	COG0583@1|root,COG0583@2|Bacteria,1G4W9@1117|Cyanobacteria,1HS3A@1161|Nostocales	1117|Cyanobacteria	K	PFAM Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CH3_k127_244319_3	1123368.AUIS01000009_gene2446	4.84e-33	133.0	COG1764@1|root,COG1764@2|Bacteria,1RH9U@1224|Proteobacteria,1S205@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	redox protein regulator of disulfide bond formation	osmC	GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006970,GO:0006972,GO:0006979,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1990748	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
CH3_k127_244319_5	1123070.KB899266_gene2496	2.525e-11	68.0	COG1758@1|root,COG1758@2|Bacteria,46W29@74201|Verrucomicrobia,2IUQD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	RNA polymerase activity	-	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
CH3_k127_244319_4	481448.Minf_2177	1.195e-31	126.0	COG0234@1|root,COG0234@2|Bacteria,46SZ8@74201|Verrucomicrobia,37GWD@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
CH3_k127_2469677_6	1123508.JH636439_gene568	3.644e-05	57.0	COG0526@1|root,COG1413@1|root,COG0526@2|Bacteria,COG1413@2|Bacteria,2J011@203682|Planctomycetes	203682|Planctomycetes	C	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
CH3_k127_2469677_3	269798.CHU_1304	7.265e-41	166.0	2AQME@1|root,31FUG@2|Bacteria,4NRV3@976|Bacteroidetes,47VCI@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_2469677_4	1121957.ATVL01000007_gene2357	1.155e-37	158.0	COG4330@1|root,COG4330@2|Bacteria,4NNT4@976|Bacteroidetes,47PCZ@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1361)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1361
CH3_k127_2469677_2	382464.ABSI01000020_gene153	8.659e-45	171.0	COG2194@1|root,COG2194@2|Bacteria,46XHR@74201|Verrucomicrobia,2IVYD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	sulfuric ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_2469677_1	497964.CfE428DRAFT_0298	4.46e-61	220.0	COG2258@1|root,COG2258@2|Bacteria,46VBP@74201|Verrucomicrobia	74201|Verrucomicrobia	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_2469677_5	452637.Oter_0903	1.166e-22	102.0	COG1917@1|root,COG1917@2|Bacteria,46WMQ@74201|Verrucomicrobia,3K8IQ@414999|Opitutae	414999|Opitutae	S	PFAM Cupin 2 conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CH3_k127_2469677_0	497964.CfE428DRAFT_6615	1.327e-223	704.0	COG1902@1|root,COG1902@2|Bacteria	2|Bacteria	C	pentaerythritol trinitrate reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red,Oxidored_FMN
CH3_k127_2520643_1	880526.KE386488_gene1576	9.646e-93	340.0	COG0823@1|root,COG0823@2|Bacteria,4NIGD@976|Bacteroidetes,2G2P7@200643|Bacteroidia	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_2520643_0	1122931.AUAE01000028_gene155	3.438e-258	827.0	COG0823@1|root,COG0823@2|Bacteria,4NIGD@976|Bacteroidetes,2G2P7@200643|Bacteroidia	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_2520643_2	663610.JQKO01000019_gene3046	1.107e-22	110.0	COG0438@1|root,COG0457@1|root,COG0438@2|Bacteria,COG0457@2|Bacteria,1R9FR@1224|Proteobacteria,2U76X@28211|Alphaproteobacteria,3NC43@45404|Beijerinckiaceae	28211|Alphaproteobacteria	M	F5/8 type C domain	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Methyltransf_21
CH3_k127_2641544_1	1337936.IJ00_19585	1.347e-36	143.0	COG1487@1|root,COG1487@2|Bacteria,1G8NQ@1117|Cyanobacteria,1HSQK@1161|Nostocales	1117|Cyanobacteria	S	Large family of predicted nucleotide-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	PIN
CH3_k127_2641544_3	32057.KB217478_gene5607	3.292e-05	49.0	COG0553@1|root,COG3886@1|root,COG0553@2|Bacteria,COG3886@2|Bacteria,1FZVD@1117|Cyanobacteria,1HP5E@1161|Nostocales	1117|Cyanobacteria	L	PLD-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,PLDc_2,SNF2_N
CH3_k127_2641544_4	718252.FP2_00450	4.395e-05	54.0	COG2856@1|root,COG2856@2|Bacteria,1UY38@1239|Firmicutes,24DU5@186801|Clostridia,3WH3S@541000|Ruminococcaceae	186801|Clostridia	E	IrrE N-terminal-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M78
CH3_k127_2641544_2	933262.AXAM01000049_gene3260	2.792e-17	85.0	COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,42RB7@68525|delta/epsilon subdivisions,2WN5V@28221|Deltaproteobacteria,2MJQK@213118|Desulfobacterales	28221|Deltaproteobacteria	L	RadC-like JAB domain	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
CH3_k127_2641544_0	289376.THEYE_A1190	6.926e-43	173.0	COG1061@1|root,COG3587@1|root,COG1061@2|Bacteria,COG3587@2|Bacteria	2|Bacteria	L	Type III restriction enzyme, res subunit	resA	-	3.1.21.5	ko:K01156	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Helicase_C,ResIII
CH3_k127_2649501_9	869213.JCM21142_83218	0.0001182	54.0	COG1621@1|root,COG1621@2|Bacteria,4NG4M@976|Bacteroidetes,47TNW@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolases family 43	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
CH3_k127_2649501_8	1123276.KB893246_gene561	1.892e-14	89.0	COG2010@1|root,COG3345@1|root,COG4625@1|root,COG2010@2|Bacteria,COG3345@2|Bacteria,COG4625@2|Bacteria,4NJDV@976|Bacteroidetes,47NUN@768503|Cytophagia	976|Bacteroidetes	E	PFAM Di-glucose binding within endoplasmic reticulum	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Malectin,NPCBM,PA14,RicinB_lectin_2
CH3_k127_2649501_5	1211813.CAPH01000017_gene773	2.41e-45	190.0	COG3408@1|root,COG3408@2|Bacteria,4P4HZ@976|Bacteroidetes	976|Bacteroidetes	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_2649501_3	497964.CfE428DRAFT_3455	1.42e-71	256.0	COG0859@1|root,COG1560@1|root,COG0859@2|Bacteria,COG1560@2|Bacteria,46SSR@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	2.3.1.241	ko:K02517,ko:K02843	ko00540,ko01100,map00540,map01100	M00060,M00080	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9,Lip_A_acyltrans
CH3_k127_2649501_6	497964.CfE428DRAFT_3455	4.229e-40	164.0	COG0859@1|root,COG1560@1|root,COG0859@2|Bacteria,COG1560@2|Bacteria,46SSR@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	2.3.1.241	ko:K02517,ko:K02843	ko00540,ko01100,map00540,map01100	M00060,M00080	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9,Lip_A_acyltrans
CH3_k127_2649501_1	1156937.MFUM_690053	1.168e-118	392.0	COG1663@1|root,COG1663@2|Bacteria,46SBI@74201|Verrucomicrobia,37G5N@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
CH3_k127_2649501_0	344747.PM8797T_07534	1.1e-174	560.0	COG1073@1|root,COG1073@2|Bacteria,2IWT8@203682|Planctomycetes	203682|Planctomycetes	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_2649501_2	497964.CfE428DRAFT_2711	3.191e-89	310.0	COG0544@1|root,COG0544@2|Bacteria,46SJZ@74201|Verrucomicrobia	74201|Verrucomicrobia	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
CH3_k127_2649501_7	710696.Intca_1127	1.735e-26	125.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,BNR,BNR_2,DUF11,SBBP
CH3_k127_2649501_4	497964.CfE428DRAFT_5484	1.264e-62	222.0	COG0323@1|root,COG0323@2|Bacteria,46SG5@74201|Verrucomicrobia	74201|Verrucomicrobia	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
CH3_k127_2677328_1	509191.AEDB02000002_gene1137	2.767e-99	349.0	COG0823@1|root,COG0823@2|Bacteria,1VP24@1239|Firmicutes,24WTQ@186801|Clostridia,3WN5Z@541000|Ruminococcaceae	186801|Clostridia	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
CH3_k127_2677328_3	663610.JQKO01000019_gene3046	3.45e-23	117.0	COG0438@1|root,COG0457@1|root,COG0438@2|Bacteria,COG0457@2|Bacteria,1R9FR@1224|Proteobacteria,2U76X@28211|Alphaproteobacteria,3NC43@45404|Beijerinckiaceae	28211|Alphaproteobacteria	M	F5/8 type C domain	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Methyltransf_21
CH3_k127_2677328_0	509191.AEDB02000002_gene1137	1.244e-105	380.0	COG0823@1|root,COG0823@2|Bacteria,1VP24@1239|Firmicutes,24WTQ@186801|Clostridia,3WN5Z@541000|Ruminococcaceae	186801|Clostridia	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
CH3_k127_2677328_2	1077285.AGDG01000021_gene776	6.448e-85	292.0	COG1520@1|root,COG1520@2|Bacteria,4NM00@976|Bacteroidetes,2FR1A@200643|Bacteroidia,4ANP9@815|Bacteroidaceae	976|Bacteroidetes	S	unsaturated rhamnogalacturonyl hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotrans,Glyco_hydro_88,PQQ_2
CH3_k127_2685187_3	1122611.KB903963_gene4742	6.56e-37	152.0	COG2362@1|root,COG2362@2|Bacteria,2GK6A@201174|Actinobacteria,4EGCR@85012|Streptosporangiales	201174|Actinobacteria	E	D-aminopeptidase	-	-	-	ko:K16203	-	-	-	-	ko00000,ko01000,ko01002	3.A.1.5.2	-	-	Peptidase_M55
CH3_k127_2685187_1	1267535.KB906767_gene3448	1.474e-73	262.0	COG5434@1|root,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CBM_6,F5_F8_type_C,Pectate_lyase_3
CH3_k127_2685187_0	861299.J421_5653	4.319e-128	426.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CH3_k127_2685187_2	32057.KB217478_gene7545	1.529e-48	185.0	COG2730@1|root,COG2730@2|Bacteria,1G3EZ@1117|Cyanobacteria	1117|Cyanobacteria	G	Protein of unknown function (DUF4038)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF4038
CH3_k127_2687416_5	497964.CfE428DRAFT_5662	2.417e-44	168.0	COG0249@1|root,COG0249@2|Bacteria,46SCK@74201|Verrucomicrobia	74201|Verrucomicrobia	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
CH3_k127_2687416_2	1379698.RBG1_1C00001G1138	2.203e-119	394.0	COG0249@1|root,COG0249@2|Bacteria,2NNN6@2323|unclassified Bacteria	2|Bacteria	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
CH3_k127_2687416_3	661478.OP10G_2908	1.394e-116	383.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	ybhF-C	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
CH3_k127_2687416_4	1267534.KB906755_gene4489	2.655e-87	301.0	COG0842@1|root,COG0842@2|Bacteria,3Y4H7@57723|Acidobacteria,2JN2Y@204432|Acidobacteriia	204432|Acidobacteriia	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
CH3_k127_2687416_6	1096930.L284_00460	4.083e-05	55.0	COG5349@1|root,COG5349@2|Bacteria,1N0PN@1224|Proteobacteria,2UBSH@28211|Alphaproteobacteria,2K5S3@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF983)	-	-	-	-	-	-	-	-	-	-	-	-	DUF983
CH3_k127_2687416_1	1254432.SCE1572_02560	5.216e-139	456.0	COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,42PFG@68525|delta/epsilon subdivisions,2WKPM@28221|Deltaproteobacteria,2YTUX@29|Myxococcales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
CH3_k127_2687416_0	709986.Deima_0518	2.856e-153	504.0	COG1092@1|root,COG1092@2|Bacteria,1WK2R@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	PFAM S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
CH3_k127_2689467_1	517418.Ctha_1399	8.327e-102	343.0	COG1331@1|root,COG1331@2|Bacteria,1FDQN@1090|Chlorobi	1090|Chlorobi	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
CH3_k127_2689467_10	1123070.KB899249_gene301	4.115e-11	72.0	COG1266@1|root,COG1266@2|Bacteria,46T6D@74201|Verrucomicrobia,2IUVK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
CH3_k127_2689467_4	497964.CfE428DRAFT_3691	1.295e-76	267.0	COG0611@1|root,COG0611@2|Bacteria,46SV7@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
CH3_k127_2689467_8	1042156.CXIVA_02020	1.242e-25	111.0	COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,24MSS@186801|Clostridia,36IUF@31979|Clostridiaceae	186801|Clostridia	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	ydiB	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
CH3_k127_2689467_9	1034345.CAEM01000007_gene1354	1.254e-16	89.0	COG0454@1|root,COG0533@1|root,COG0456@2|Bacteria,COG0533@2|Bacteria,2GJ98@201174|Actinobacteria,4CUKY@84998|Coriobacteriia	84998|Coriobacteriia	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Acetyltransf_1,Peptidase_M22
CH3_k127_2689467_7	452637.Oter_0887	1.581e-49	197.0	COG4726@1|root,COG4726@2|Bacteria,46VER@74201|Verrucomicrobia,3K9MT@414999|Opitutae	414999|Opitutae	NU	Pilus assembly protein PilX	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_2689467_6	497964.CfE428DRAFT_5674	6.588e-50	186.0	COG0586@1|root,COG0586@2|Bacteria,46SWW@74201|Verrucomicrobia	74201|Verrucomicrobia	S	SNARE associated Golgi protein	dedA	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
CH3_k127_2689467_3	497964.CfE428DRAFT_0418	3.666e-86	297.0	COG1573@1|root,COG1573@2|Bacteria,46SSB@74201|Verrucomicrobia	74201|Verrucomicrobia	L	TIGRFAM phage SPO1 DNA polymerase-related protein	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
CH3_k127_2689467_2	234267.Acid_2605	5.011e-89	301.0	COG2133@1|root,COG2133@2|Bacteria,3Y3FI@57723|Acidobacteria	57723|Acidobacteria	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CH3_k127_2689467_0	1210884.HG799465_gene12146	1.494e-140	459.0	COG1520@1|root,COG1520@2|Bacteria,2J2YU@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CH3_k127_2689467_5	1301098.PKB_0417	2.564e-63	221.0	COG2314@1|root,COG2314@2|Bacteria,1RHUU@1224|Proteobacteria,1S694@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	TM2
CH3_k127_2694415_3	641524.ADICYQ_5814	6.576e-17	89.0	COG4692@1|root,COG4692@2|Bacteria,4NEYM@976|Bacteroidetes,47T52@768503|Cytophagia	976|Bacteroidetes	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
CH3_k127_2694415_2	1408473.JHXO01000009_gene3340	2.91e-17	85.0	2DR6U@1|root,33AFB@2|Bacteria,4P5F6@976|Bacteroidetes,2FYZD@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_2694415_0	1121403.AUCV01000020_gene3110	6.563e-120	395.0	COG1244@1|root,COG1244@2|Bacteria	2|Bacteria	S	Elongator protein 3, MiaB family, Radical SAM	-	-	-	ko:K06936	-	-	-	-	ko00000	-	-	-	-
CH3_k127_2694415_1	1340493.JNIF01000003_gene3969	4.871e-21	92.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CH3_k127_2724406_3	1454004.AW11_00407	1.378e-18	94.0	COG0012@1|root,COG0012@2|Bacteria,1Q097@1224|Proteobacteria,2W504@28216|Betaproteobacteria	28216|Betaproteobacteria	J	GTP binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_2724406_1	1121403.AUCV01000030_gene2776	3.279e-65	229.0	COG4380@1|root,COG4380@2|Bacteria,1R3WM@1224|Proteobacteria,42PVR@68525|delta/epsilon subdivisions,2WR51@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Putative bacterial lipoprotein (DUF799)	-	-	-	-	-	-	-	-	-	-	-	-	DUF799
CH3_k127_2724406_2	1286106.MPL1_05974	3.066e-25	111.0	COG4259@1|root,COG4259@2|Bacteria,1N7DV@1224|Proteobacteria,1S7AS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Lipoprotein	Z012_10670	-	-	-	-	-	-	-	-	-	-	-	DUF4810
CH3_k127_2724406_0	1123257.AUFV01000009_gene2146	2.241e-95	317.0	COG1462@1|root,COG1462@2|Bacteria,1NDU8@1224|Proteobacteria,1RPPY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Curli production assembly transport component CsgG	csgG	-	-	-	-	-	-	-	-	-	-	-	CsgG
CH3_k127_2732600_8	861299.J421_1753	1.398e-65	229.0	COG0446@1|root,COG4888@1|root,COG0446@2|Bacteria,COG4888@2|Bacteria	2|Bacteria	G	ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,Pyr_redox_2,UnbV_ASPIC,VCBS
CH3_k127_2732600_1	1121346.KB899817_gene3149	9.984e-296	921.0	COG0129@1|root,COG0129@2|Bacteria,1U56J@1239|Firmicutes,4HD31@91061|Bacilli,26U7U@186822|Paenibacillaceae	91061|Bacilli	EG	Belongs to the IlvD Edd family	-	-	4.2.1.82	ko:K22396	ko00040,map00040	-	R02429	RC00543	ko00000,ko00001,ko01000	-	-	-	ILVD_EDD
CH3_k127_2732600_6	530564.Psta_0399	1.107e-83	287.0	COG3970@1|root,COG3970@2|Bacteria,2IWUC@203682|Planctomycetes	203682|Planctomycetes	S	fumarylacetoacetate (FAA) hydrolase	-	-	4.2.1.141	ko:K14259	ko00040,map00040	-	R09186	RC00429	ko00000,ko00001,ko01000	-	-	-	FAA_hydrolase
CH3_k127_2732600_2	243090.RB10165	1.356e-152	514.0	COG1305@1|root,COG3509@1|root,COG1305@2|Bacteria,COG3509@2|Bacteria,2IX6R@203682|Planctomycetes	203682|Planctomycetes	Q	depolymerase	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,DLH,Transglut_core
CH3_k127_2732600_3	1150600.ADIARSV_4037	7.783e-130	427.0	28HII@1|root,2Z7TZ@2|Bacteria,4NHR6@976|Bacteroidetes,1INR1@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_2732600_5	661478.OP10G_2091	2.019e-114	383.0	COG4030@1|root,COG4030@2|Bacteria	2|Bacteria	M	Protein of unknown function (DUF2961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
CH3_k127_2732600_9	1192034.CAP_8203	2.718e-31	145.0	COG5184@1|root,COG5184@2|Bacteria,1R504@1224|Proteobacteria,42QHC@68525|delta/epsilon subdivisions,2WKUI@28221|Deltaproteobacteria,2YU2V@29|Myxococcales	28221|Deltaproteobacteria	DZ	Alpha-tubulin suppressor and related RCC1 domain-containing	-	-	-	-	-	-	-	-	-	-	-	-	RCC1
CH3_k127_2732600_11	452637.Oter_1999	7.41e-14	87.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5
CH3_k127_2732600_4	935845.JADQ01000029_gene1230	3.01e-123	444.0	COG2755@1|root,COG4257@1|root,COG5184@1|root,COG2755@2|Bacteria,COG4257@2|Bacteria,COG5184@2|Bacteria,1UZD4@1239|Firmicutes,4HD48@91061|Bacilli,26VBQ@186822|Paenibacillaceae	91061|Bacilli	DZ	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin-like,RCC1_2,SLH
CH3_k127_2732600_14	886293.Sinac_0949	1.251e-07	53.0	COG3250@1|root,COG3250@2|Bacteria,2IWTW@203682|Planctomycetes	203682|Planctomycetes	G	Glycosyl hydrolases family 2	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_43
CH3_k127_2732600_7	1396141.BATP01000030_gene3773	4.663e-80	273.0	COG3250@1|root,COG3387@1|root,COG3250@2|Bacteria,COG3387@2|Bacteria	2|Bacteria	G	glucan 1,4-alpha-glucosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1793,DUF4964,DUF4965,DUF5127,RicinB_lectin_2
CH3_k127_2732600_0	661478.OP10G_2213	2.198e-315	998.0	COG1621@1|root,COG4354@1|root,COG1621@2|Bacteria,COG4354@2|Bacteria	2|Bacteria	G	intracellular protein transport	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2,DUF608,Glyco_hydr_116N,VCBS
CH3_k127_2732600_13	1046714.AMRX01000008_gene918	4.284e-11	65.0	COG4030@1|root,COG4030@2|Bacteria,1NSDB@1224|Proteobacteria,1SC1R@1236|Gammaproteobacteria,469NN@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
CH3_k127_2732600_12	1303518.CCALI_02295	6.809e-13	78.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
CH3_k127_2732600_10	1303518.CCALI_02638	3.258e-16	89.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
CH3_k127_2777343_7	583355.Caka_1736	5.75e-37	154.0	COG2312@1|root,COG2312@2|Bacteria,46TMX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
CH3_k127_2777343_8	56780.SYN_01800	1.271e-31	134.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,42MBA@68525|delta/epsilon subdivisions,2WKX9@28221|Deltaproteobacteria,2MQGD@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
CH3_k127_2777343_3	314230.DSM3645_06659	2.411e-73	265.0	COG4850@1|root,COG4850@2|Bacteria,2IZDS@203682|Planctomycetes	203682|Planctomycetes	S	Uncharacterized conserved protein (DUF2183)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2183
CH3_k127_2777343_4	543728.Vapar_4986	5.559e-66	241.0	COG0707@1|root,COG0707@2|Bacteria,1QU89@1224|Proteobacteria,2VKVF@28216|Betaproteobacteria,4AFFZ@80864|Comamonadaceae	28216|Betaproteobacteria	M	Monogalactosyldiacylglycerol (MGDG) synthase	-	-	2.4.1.315,2.4.1.46	ko:K03429,ko:K03715	ko00561,ko01100,map00561,map01100	-	R02689,R02691,R04377	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT28	-	Glyco_tran_28_C,MGDG_synth
CH3_k127_2777343_1	886293.Sinac_0656	1.122e-240	757.0	COG1053@1|root,COG1053@2|Bacteria,2IYNS@203682|Planctomycetes	203682|Planctomycetes	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
CH3_k127_2777343_9	977880.RALTA_A2916	2.352e-22	100.0	COG1324@1|root,COG1324@2|Bacteria,1N6TN@1224|Proteobacteria,2VUC8@28216|Betaproteobacteria,1KHET@119060|Burkholderiaceae	28216|Betaproteobacteria	P	tolerance protein	cutA	GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
CH3_k127_2777343_6	215803.DB30_3302	9.367e-38	150.0	2F6YT@1|root,33ZET@2|Bacteria,1Q2TV@1224|Proteobacteria,438FU@68525|delta/epsilon subdivisions,2X3QS@28221|Deltaproteobacteria,2YWVH@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_2777343_0	497964.CfE428DRAFT_1508	6.895e-242	759.0	COG1620@1|root,COG1620@2|Bacteria,46UQW@74201|Verrucomicrobia	74201|Verrucomicrobia	C	L-lactate permease	-	-	-	-	-	-	-	-	-	-	-	-	Lactate_perm
CH3_k127_2777343_11	357808.RoseRS_4349	1.515e-13	78.0	COG1247@1|root,COG1247@2|Bacteria,2G9YI@200795|Chloroflexi,377A3@32061|Chloroflexia	32061|Chloroflexia	M	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CH3_k127_2777343_10	1396418.BATQ01000058_gene110	4.757e-21	95.0	2EMGZ@1|root,33F5K@2|Bacteria,46TB4@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_2777343_2	1210884.HG799472_gene14911	2.628e-115	384.0	COG1520@1|root,COG1520@2|Bacteria,2IWXJ@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CH3_k127_2777343_5	452637.Oter_1003	3.692e-39	150.0	COG4299@1|root,COG4299@2|Bacteria,46S60@74201|Verrucomicrobia	74201|Verrucomicrobia	S	COGs COG4299 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624,DUF5009
CH3_k127_2780905_0	497964.CfE428DRAFT_6239	4.062e-53	188.0	COG0347@1|root,COG0347@2|Bacteria,46VXS@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Belongs to the P(II) protein family	-	-	-	-	-	-	-	-	-	-	-	-	P-II
CH3_k127_2780905_2	530564.Psta_1718	8.456e-23	101.0	COG2337@1|root,COG2337@2|Bacteria	2|Bacteria	T	Toxic component of a toxin-antitoxin (TA) module	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
CH3_k127_2780905_1	1121456.ATVA01000014_gene561	5.799e-41	160.0	COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,42SS8@68525|delta/epsilon subdivisions,2WPMH@28221|Deltaproteobacteria,2MAUU@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Metallophosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
CH3_k127_2780905_3	641491.DND132_0975	6.632e-17	84.0	COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,42SS8@68525|delta/epsilon subdivisions,2WPMH@28221|Deltaproteobacteria,2MAUU@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Metallophosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
CH3_k127_2782485_13	794903.OPIT5_20525	5.178e-08	57.0	COG1943@1|root,COG1943@2|Bacteria,46XEX@74201|Verrucomicrobia,3K9MH@414999|Opitutae	414999|Opitutae	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	-
CH3_k127_2782485_7	1210884.HG799476_gene15380	2.965e-57	229.0	COG1595@1|root,COG1595@2|Bacteria,2IZH8@203682|Planctomycetes	203682|Planctomycetes	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Abhydrolase_2
CH3_k127_2782485_2	497964.CfE428DRAFT_4863	3.322e-106	386.0	COG0515@1|root,COG0515@2|Bacteria	497964.CfE428DRAFT_4863|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_2782485_14	596152.DesU5LDRAFT_2094	2.378e-07	63.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42N0H@68525|delta/epsilon subdivisions,2WIYD@28221|Deltaproteobacteria,2M82M@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Belongs to the peptidase M16 family	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
CH3_k127_2782485_4	497964.CfE428DRAFT_4864	3.994e-78	270.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_2782485_5	221288.JH992901_gene3760	3.405e-68	237.0	COG1247@1|root,COG1247@2|Bacteria,1G8E2@1117|Cyanobacteria	1117|Cyanobacteria	M	Acetyltransferase (GNAT) domain	-	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
CH3_k127_2782485_1	472759.Nhal_1554	1.402e-139	458.0	COG0457@1|root,COG0457@2|Bacteria,1N0A9@1224|Proteobacteria,1RZSZ@1236|Gammaproteobacteria,1X0HU@135613|Chromatiales	135613|Chromatiales	S	PFAM Tetratricopeptide TPR_4	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_2782485_15	1173023.KE650771_gene983	0.0001803	47.0	COG0457@1|root,COG0457@2|Bacteria,1G31A@1117|Cyanobacteria,1JK03@1189|Stigonemataceae	1117|Cyanobacteria	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8
CH3_k127_2782485_0	266117.Rxyl_3138	5.033e-140	454.0	COG1533@1|root,COG1533@2|Bacteria,2GM31@201174|Actinobacteria,4CQAG@84995|Rubrobacteria	84995|Rubrobacteria	L	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
CH3_k127_2782485_10	143224.JQMD01000002_gene4173	2.88e-34	137.0	COG2755@1|root,COG2755@2|Bacteria,4NQAK@976|Bacteroidetes,1I340@117743|Flavobacteriia	976|Bacteroidetes	E	Stress responsive A/B Barrel Domain	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
CH3_k127_2782485_6	497964.CfE428DRAFT_4056	4.844e-67	235.0	COG2755@1|root,COG2755@2|Bacteria,46T12@74201|Verrucomicrobia	74201|Verrucomicrobia	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CH3_k127_2782485_12	566466.NOR53_2254	8.73e-13	79.0	COG2304@1|root,COG2931@1|root,COG3209@1|root,COG2304@2|Bacteria,COG2931@2|Bacteria,COG3209@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria,1J94H@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	MQ	Dystroglycan-type cadherin-like domains.	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,He_PIG,HemolysinCabind,VWA_2
CH3_k127_2782485_8	485917.Phep_1293	4.124e-57	224.0	2C4R9@1|root,32RED@2|Bacteria,4P0US@976|Bacteroidetes	976|Bacteroidetes	S	F5/8 type C domain	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C
CH3_k127_2782485_11	794903.OPIT5_12525	3.03e-20	100.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
CH3_k127_2782485_3	794903.OPIT5_24610	4.363e-82	286.0	COG0657@1|root,COG0657@2|Bacteria,46UVS@74201|Verrucomicrobia	2|Bacteria	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
CH3_k127_2782485_9	497964.CfE428DRAFT_1805	9.009e-46	170.0	COG2197@1|root,COG2197@2|Bacteria,46UBU@74201|Verrucomicrobia	74201|Verrucomicrobia	T	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CH3_k127_278520_1	1396141.BATP01000003_gene4967	3.506e-208	677.0	COG3391@1|root,COG3391@2|Bacteria,46X7X@74201|Verrucomicrobia,2IUXV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	cytochrome C peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	CCP_MauG
CH3_k127_278520_2	278963.ATWD01000001_gene2920	6.299e-180	571.0	2CK7V@1|root,2Z9WF@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_278520_4	497964.CfE428DRAFT_6276	1.442e-71	268.0	COG2755@1|root,COG2755@2|Bacteria,46SVE@74201|Verrucomicrobia	74201|Verrucomicrobia	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CH3_k127_278520_0	1123508.JH636441_gene3126	1.612e-229	732.0	COG3119@1|root,COG3119@2|Bacteria,2IX0S@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
CH3_k127_278520_5	1173027.Mic7113_4586	1.944e-40	157.0	COG4636@1|root,COG4636@2|Bacteria,1G2P0@1117|Cyanobacteria,1H6WC@1150|Oscillatoriales	1117|Cyanobacteria	T	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
CH3_k127_278520_3	452637.Oter_3559	1.143e-84	286.0	COG1070@1|root,COG1070@2|Bacteria,46SI1@74201|Verrucomicrobia,3K7BT@414999|Opitutae	414999|Opitutae	G	FGGY family of carbohydrate kinases, C-terminal domain	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
CH3_k127_2791087_5	1123070.KB899248_gene14	7.314e-30	129.0	COG0817@1|root,COG0817@2|Bacteria,46T3Y@74201|Verrucomicrobia,2IUA7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
CH3_k127_2791087_0	497964.CfE428DRAFT_4571	1.813e-68	237.0	COG0632@1|root,COG0632@2|Bacteria,46SZF@74201|Verrucomicrobia	74201|Verrucomicrobia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
CH3_k127_2791087_2	481448.Minf_0381	2.613e-48	181.0	COG2121@1|root,COG2121@2|Bacteria,46SZ0@74201|Verrucomicrobia,37GQD@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF374)	-	-	-	ko:K09778	-	-	-	-	ko00000	-	-	-	DUF374
CH3_k127_2791087_4	1403819.BATR01000092_gene2798	6.353e-33	147.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,46TTW@74201|Verrucomicrobia,2IU0H@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KLT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PEGA,Pkinase
CH3_k127_2791087_9	313628.LNTAR_23104	6.015e-08	63.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	GerE,Sigma70_r2
CH3_k127_2791087_3	153721.MYP_4858	4.494e-45	183.0	COG4733@1|root,COG4733@2|Bacteria,4NTXR@976|Bacteroidetes,47SSC@768503|Cytophagia	976|Bacteroidetes	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Laminin_G_3
CH3_k127_2791087_6	497964.CfE428DRAFT_4984	3.131e-24	119.0	COG1198@1|root,COG1198@2|Bacteria,46U3N@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
CH3_k127_2791087_1	686340.Metal_0565	5.805e-51	203.0	COG1002@1|root,COG1943@1|root,COG2890@1|root,COG1002@2|Bacteria,COG1943@2|Bacteria,COG2890@2|Bacteria,1RIWM@1224|Proteobacteria,1S7RK@1236|Gammaproteobacteria,1XFWD@135618|Methylococcales	135618|Methylococcales	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
CH3_k127_2791087_8	1160707.AJIK01000004_gene1235	4.943e-11	76.0	COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,4H9WW@91061|Bacilli,26EKT@186818|Planococcaceae	91061|Bacilli	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
CH3_k127_279441_18	640081.Dsui_2056	8.057e-09	58.0	COG1403@1|root,COG1403@2|Bacteria,1RIEZ@1224|Proteobacteria,2VTF6@28216|Betaproteobacteria,2KWR0@206389|Rhodocyclales	206389|Rhodocyclales	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
CH3_k127_279441_3	452637.Oter_1559	3.536e-85	295.0	2DVX4@1|root,33XIH@2|Bacteria,46VH6@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_279441_16	661478.OP10G_0157	5.073e-13	72.0	COG1783@1|root,COG1783@2|Bacteria	2|Bacteria	S	DNA packaging	-	-	-	ko:K06909	-	-	-	-	ko00000	-	-	-	Terminase_3,Terminase_6
CH3_k127_279441_4	398579.Spea_2275	7.435e-62	224.0	COG3291@1|root,COG3291@2|Bacteria,1QC1P@1224|Proteobacteria,1T7PF@1236|Gammaproteobacteria,2QDB3@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_279441_19	401526.TcarDRAFT_1283	1.56e-06	60.0	COG1783@1|root,COG3780@1|root,COG5525@1|root,COG1783@2|Bacteria,COG3780@2|Bacteria,COG5525@2|Bacteria	2|Bacteria	S	Phage terminase large subunit (GpA)	-	-	-	ko:K06909	-	-	-	-	ko00000	-	-	-	HTH_3,Terminase_6
CH3_k127_279441_6	1110502.TMO_2325	7.061e-50	188.0	28IAN@1|root,2Z8D8@2|Bacteria,1NJD6@1224|Proteobacteria,2U3QV@28211|Alphaproteobacteria,2JYIM@204441|Rhodospirillales	204441|Rhodospirillales	S	Domain of unknown function (DUF4055)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4055
CH3_k127_279441_15	1005395.CSV86_21761	1.594e-15	86.0	28IWE@1|root,2Z8UQ@2|Bacteria,1PS44@1224|Proteobacteria,1RRB1@1236|Gammaproteobacteria,1YXNS@136845|Pseudomonas putida group	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_279441_7	1031288.AXAA01000048_gene768	5.614e-45	173.0	2BZ9Z@1|root,2Z97E@2|Bacteria,1U6NR@1239|Firmicutes,24FZN@186801|Clostridia,36GJA@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_279441_5	991905.SL003B_p0052	2.432e-51	192.0	28K5X@1|root,2Z9UF@2|Bacteria,1R3CT@1224|Proteobacteria,2U3AI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
CH3_k127_279441_0	794903.OPIT5_12250	6.34e-133	435.0	COG4861@1|root,COG4861@2|Bacteria,46XWK@74201|Verrucomicrobia,3K9X1@414999|Opitutae	414999|Opitutae	S	Transcriptional regulator, AbiEi antitoxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_2
CH3_k127_279441_20	102129.Lepto7375DRAFT_6804	0.0003094	52.0	COG0582@1|root,COG0582@2|Bacteria,1GF6X@1117|Cyanobacteria,1HG4G@1150|Oscillatoriales	1117|Cyanobacteria	L	Phage integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_integrase
CH3_k127_279441_17	232346.JHQL01000002_gene1062	6.422e-13	78.0	COG4643@1|root,COG4643@2|Bacteria,1R5M0@1224|Proteobacteria,1RY0K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3631)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3631
CH3_k127_279441_9	643562.Daes_0503	2.324e-34	134.0	COG0640@1|root,COG0640@2|Bacteria,1N19R@1224|Proteobacteria,42TRS@68525|delta/epsilon subdivisions,2WQHU@28221|Deltaproteobacteria,2MC8X@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	SMART regulatory protein ArsR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
CH3_k127_279441_13	1499967.BAYZ01000050_gene2842	2.748e-24	103.0	COG0526@1|root,COG0526@2|Bacteria,2NQ71@2323|unclassified Bacteria	2|Bacteria	CO	Thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4369,Thioredoxin_3
CH3_k127_279441_1	525904.Tter_1451	7.225e-128	424.0	COG1249@1|root,COG1249@2|Bacteria,2NNTI@2323|unclassified Bacteria	2|Bacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
CH3_k127_279441_14	1031288.AXAA01000034_gene2180	1.699e-23	107.0	COG0509@1|root,COG4273@1|root,COG0509@2|Bacteria,COG4273@2|Bacteria,1V6WV@1239|Firmicutes,24N5H@186801|Clostridia,36JKI@31979|Clostridiaceae	186801|Clostridia	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	DGC,GCV_H
CH3_k127_279441_12	643648.Slip_2187	6.691e-25	110.0	COG4273@1|root,COG4273@2|Bacteria,1VBRH@1239|Firmicutes,24N2C@186801|Clostridia	186801|Clostridia	S	DGC domain	-	-	-	-	-	-	-	-	-	-	-	-	DGC
CH3_k127_279441_10	643648.Slip_2186	1.58e-33	138.0	COG4273@1|root,COG4273@2|Bacteria,1UPTR@1239|Firmicutes,25HNZ@186801|Clostridia	186801|Clostridia	S	DGC domain	-	-	-	-	-	-	-	-	-	-	-	-	DGC
CH3_k127_279441_11	643648.Slip_2185	1.849e-30	133.0	COG1764@1|root,COG1764@2|Bacteria,1VYMJ@1239|Firmicutes,2538T@186801|Clostridia	186801|Clostridia	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
CH3_k127_279441_2	452637.Oter_4060	3.499e-97	324.0	COG0345@1|root,COG0345@2|Bacteria	2|Bacteria	E	pyrroline-5-carboxylate reductase activity	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
CH3_k127_279441_8	452637.Oter_4059	1.932e-35	141.0	COG0526@1|root,COG0526@2|Bacteria,46W21@74201|Verrucomicrobia	74201|Verrucomicrobia	CO	Thioredoxin	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
CH3_k127_2815901_9	1123508.JH636442_gene4185	2.532e-99	337.0	COG1167@1|root,COG1167@2|Bacteria,2IY9J@203682|Planctomycetes	203682|Planctomycetes	EK	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
CH3_k127_2815901_12	317619.ANKN01000004_gene815	2.265e-45	166.0	COG0537@1|root,COG0537@2|Bacteria,1G6R2@1117|Cyanobacteria,1MMGN@1212|Prochloraceae	1117|Cyanobacteria	FG	Alternative locus ID	hit	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
CH3_k127_2815901_11	794903.OPIT5_16315	1.28e-47	175.0	COG1327@1|root,COG1327@2|Bacteria,46VCN@74201|Verrucomicrobia,3K7XU@414999|Opitutae	414999|Opitutae	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
CH3_k127_2815901_6	720554.Clocl_3102	4.036e-139	449.0	COG0119@1|root,COG0119@2|Bacteria,1TS0A@1239|Firmicutes,247MU@186801|Clostridia,3WHBT@541000|Ruminococcaceae	186801|Clostridia	E	HMGL-like	-	-	4.1.3.39	ko:K01666	ko00360,ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00360,map00362,map00621,map00622,map01100,map01120,map01220	M00545,M00569	R00750	RC00307,RC00371	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
CH3_k127_2815901_4	497964.CfE428DRAFT_4544	1.126e-155	501.0	COG0714@1|root,COG0714@2|Bacteria,46TCY@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM ATPase associated with various cellular activities AAA_3	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CH3_k127_2815901_8	497964.CfE428DRAFT_4543	9.792e-129	420.0	COG1721@1|root,COG1721@2|Bacteria,46TKV@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CH3_k127_2815901_2	497964.CfE428DRAFT_4542	3.938e-247	782.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	BatA,CARDB,DUF4091,Glyco_hydro_71,HYR,Hint_2,Peptidase_C11
CH3_k127_2815901_1	497964.CfE428DRAFT_2093	7.849e-252	796.0	COG2304@1|root,COG2304@2|Bacteria,46UTA@74201|Verrucomicrobia	74201|Verrucomicrobia	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_2815901_0	497964.CfE428DRAFT_4534	1.717e-261	837.0	COG1196@1|root,COG1196@2|Bacteria,46TX7@74201|Verrucomicrobia	74201|Verrucomicrobia	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_2815901_10	497964.CfE428DRAFT_4533	6.755e-88	297.0	COG1657@1|root,COG1657@2|Bacteria,46TYK@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
CH3_k127_2815901_3	497964.CfE428DRAFT_4532	2.32e-159	516.0	COG0737@1|root,COG0737@2|Bacteria,46TFI@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
CH3_k127_2815901_13	794903.OPIT5_25305	2.129e-27	121.0	COG4232@1|root,COG4232@2|Bacteria	2|Bacteria	CO	protein-disulfide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin,Thioredoxin_7
CH3_k127_2815901_7	886293.Sinac_2458	2.521e-132	432.0	COG0399@1|root,COG0399@2|Bacteria,2IXZR@203682|Planctomycetes	203682|Planctomycetes	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
CH3_k127_2815901_14	243230.DR_0026	4.858e-09	67.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31,Ubie_methyltran
CH3_k127_2815901_5	1236959.BAMT01000001_gene1712	1.826e-154	513.0	COG0515@1|root,COG0515@2|Bacteria,1R6F6@1224|Proteobacteria,2W1UW@28216|Betaproteobacteria,2KKN2@206350|Nitrosomonadales	206350|Nitrosomonadales	KLT	Lipopolysaccharide kinase (Kdo/WaaP) family	-	-	-	-	-	-	-	-	-	-	-	-	Kdo
CH3_k127_2834202_1	526227.Mesil_3282	8.112e-11	68.0	COG1848@1|root,COG1848@2|Bacteria	2|Bacteria	G	Toxic component of a toxin-antitoxin (TA) module. An RNase	vapC	GO:0005575,GO:0005576	-	-	-	-	-	-	-	-	-	-	PIN
CH3_k127_2834202_3	196490.AUEZ01000233_gene1409	1.34e-06	55.0	COG3547@1|root,COG3547@2|Bacteria,1MW0N@1224|Proteobacteria,2TUGE@28211|Alphaproteobacteria,3JX5I@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	PFAM transposase IS116 IS110 IS902 family	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
CH3_k127_2834202_2	1396141.BATP01000022_gene455	1.409e-08	68.0	COG4675@1|root,COG4675@2|Bacteria,46X85@74201|Verrucomicrobia,2IUYY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Phage Tail Collar Domain	-	-	-	-	-	-	-	-	-	-	-	-	Collar
CH3_k127_2834202_0	1396141.BATP01000040_gene2082	3.871e-16	93.0	COG2247@1|root,COG3291@1|root,COG4733@1|root,COG5492@1|root,COG2247@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria,COG5492@2|Bacteria,46TXW@74201|Verrucomicrobia	74201|Verrucomicrobia	M	cell wall binding repeat	-	-	-	-	-	-	-	-	-	-	-	-	PA14
CH3_k127_2862244_1	497964.CfE428DRAFT_0138	6.886e-120	391.0	28ND0@1|root,2ZBFU@2|Bacteria,46UZ8@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_2862244_0	452637.Oter_1839	1.991e-259	814.0	COG5492@1|root,COG5492@2|Bacteria,46UXF@74201|Verrucomicrobia,3K8Z6@414999|Opitutae	414999|Opitutae	N	Putative collagen-binding domain of a collagenase	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF5060
CH3_k127_2862244_4	411490.ANACAC_03351	4.425e-47	183.0	COG0371@1|root,COG0371@2|Bacteria,1V994@1239|Firmicutes	1239|Firmicutes	C	Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH_2
CH3_k127_2862244_6	497964.CfE428DRAFT_1390	8.943e-20	94.0	2ET1N@1|root,33KJT@2|Bacteria,46TA1@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_2862244_3	497964.CfE428DRAFT_1388	2.568e-66	231.0	COG1595@1|root,COG1595@2|Bacteria,46STJ@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CH3_k127_2862244_2	1408445.JHXP01000026_gene2302	7.65e-76	274.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,1S5KR@1236|Gammaproteobacteria,1JGK2@118969|Legionellales	118969|Legionellales	M	Beta-eliminating lyase	-	-	2.6.1.109	ko:K19715	-	-	R11395	RC00160	ko00000,ko01000,ko01005	-	-	-	DegT_DnrJ_EryC1
CH3_k127_2862244_7	1394178.AWOO02000001_gene1498	1.89e-11	71.0	COG0531@1|root,COG0531@2|Bacteria,2GIWQ@201174|Actinobacteria,4EHVN@85012|Streptosporangiales	201174|Actinobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
CH3_k127_2879674_12	1123278.KB893444_gene1682	2.398e-11	64.0	COG0673@1|root,COG0673@2|Bacteria,4NHFK@976|Bacteroidetes,47MBN@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CH3_k127_2879674_6	1303518.CCALI_01216	2.577e-81	278.0	COG0512@1|root,COG0512@2|Bacteria	2|Bacteria	EH	Glutamine amidotransferase of anthranilate synthase	trpG	GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	2.4.2.18,2.6.1.85,4.1.3.27	ko:K01658,ko:K01664,ko:K13497	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01073,R01716	RC00010,RC00440,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2496	GATase,Glycos_trans_3N,Glycos_transf_3
CH3_k127_2879674_10	331678.Cphamn1_0275	3.417e-20	98.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
CH3_k127_2879674_11	452637.Oter_2961	1.939e-15	79.0	COG1925@1|root,COG1925@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	ptsH	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005981,GO:0006109,GO:0006793,GO:0006796,GO:0006810,GO:0008047,GO:0008150,GO:0008152,GO:0008643,GO:0008965,GO:0008982,GO:0009401,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010604,GO:0010675,GO:0010676,GO:0010906,GO:0010907,GO:0015144,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0019197,GO:0019222,GO:0022804,GO:0022857,GO:0030234,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0032881,GO:0032991,GO:0034219,GO:0043085,GO:0043467,GO:0043470,GO:0043471,GO:0044093,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0045819,GO:0045913,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0051179,GO:0051234,GO:0055085,GO:0060255,GO:0062012,GO:0062013,GO:0065007,GO:0065009,GO:0070873,GO:0070875,GO:0071702,GO:0080090,GO:0098772	-	ko:K02784,ko:K11189	ko02060,map02060	-	-	-	ko00000,ko00001,ko02000	4.A.2.1,8.A.8.1.1	-	e_coli_core.b2415,iAF1260.b2415,iB21_1397.B21_02276,iBWG_1329.BWG_2177,iE2348C_1286.E2348C_2601,iEC042_1314.EC042_2624,iEC55989_1330.EC55989_2705,iECABU_c1320.ECABU_c27360,iECBD_1354.ECBD_1266,iECB_1328.ECB_02315,iECDH10B_1368.ECDH10B_2580,iECDH1ME8569_1439.ECDH1ME8569_2349,iECDH1ME8569_1439.EcDH1_1246,iECD_1391.ECD_02315,iECED1_1282.ECED1_2859,iECH74115_1262.ECH74115_3646,iECIAI1_1343.ECIAI1_2473,iECIAI39_1322.ECIAI39_2561,iECNA114_1301.ECNA114_2492,iECO103_1326.ECO103_2934,iECO111_1330.ECO111_3145,iECO26_1355.ECO26_3468,iECOK1_1307.ECOK1_2732,iECP_1309.ECP_2439,iECS88_1305.ECS88_2605,iECSE_1348.ECSE_2706,iECSF_1327.ECSF_2279,iECSP_1301.ECSP_3363,iECUMN_1333.ECUMN_2737,iECW_1372.ECW_m2644,iECs_1301.ECs3287,iEKO11_1354.EKO11_1313,iETEC_1333.ETEC_2528,iEcDH1_1363.EcDH1_1246,iEcE24377_1341.EcE24377A_2702,iEcHS_1320.EcHS_A2550,iEcSMS35_1347.EcSMS35_2570,iEcolC_1368.EcolC_1263,iG2583_1286.G2583_2947,iJO1366.b2415,iJR904.b2415,iLF82_1304.LF82_1769,iNRG857_1313.NRG857_12110,iPC815.YPO2993,iSBO_1134.SBO_2439,iSDY_1059.SDY_2612,iSFV_1184.SFV_2467,iSF_1195.SF2470,iSFxv_1172.SFxv_2719,iSSON_1240.SSON_2504,iS_1188.S2616,iSbBS512_1146.SbBS512_E2765,iUMN146_1321.UM146_04545,iUMNK88_1353.UMNK88_3017,iUTI89_1310.UTI89_C2749,iWFL_1372.ECW_m2644,iY75_1357.Y75_RS12655,iZ_1308.Z3681,ic_1306.c2950	PTS-HPr
CH3_k127_2879674_9	497964.CfE428DRAFT_5080	3.794e-26	116.0	29N11@1|root,344HT@2|Bacteria,46WBB@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_2879674_5	497964.CfE428DRAFT_5081	7.434e-150	488.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CH3_k127_2879674_2	1396141.BATP01000003_gene5036	4.888e-284	930.0	COG2931@1|root,COG3299@1|root,COG4733@1|root,COG5267@1|root,COG2931@2|Bacteria,COG3299@2|Bacteria,COG4733@2|Bacteria,COG5267@2|Bacteria,46TXW@74201|Verrucomicrobia,2IWPZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	Q	PA14	-	-	-	-	-	-	-	-	-	-	-	-	PA14
CH3_k127_2879674_7	1499967.BAYZ01000062_gene6031	3.158e-77	281.0	28K2M@1|root,2Z9RY@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
CH3_k127_2879674_13	458817.Shal_3325	7.812e-05	55.0	COG4932@1|root,COG4932@2|Bacteria,1R94W@1224|Proteobacteria,1RSPU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_2879674_8	1123508.JH636441_gene3117	5.244e-34	141.0	COG1413@1|root,COG1413@2|Bacteria,2J2VX@203682|Planctomycetes	203682|Planctomycetes	C	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CH3_k127_2879674_4	1382359.JIAL01000001_gene1319	4.008e-175	563.0	COG0644@1|root,COG0644@2|Bacteria	2|Bacteria	C	geranylgeranyl reductase activity	prnC	-	1.14.19.49	ko:K14257	ko00253,ko00404,ko01057,ko01130,map00253,map00404,map01057,map01130	M00790,M00823	R05456,R11106,R11478	RC00949	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_halogenase
CH3_k127_2879674_1	861299.J421_1753	1.238e-285	921.0	COG0446@1|root,COG4888@1|root,COG0446@2|Bacteria,COG4888@2|Bacteria	2|Bacteria	G	ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,Pyr_redox_2,UnbV_ASPIC,VCBS
CH3_k127_2879674_0	344747.PM8797T_03935	0.0	1101.0	COG0457@1|root,COG0457@2|Bacteria,2IXP3@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,TPR_16
CH3_k127_2879674_3	243090.RB11088	8.48e-206	661.0	COG0457@1|root,COG0457@2|Bacteria,2IYBX@203682|Planctomycetes	203682|Planctomycetes	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
CH3_k127_2896357_0	875328.JDM601_0480	5.369e-320	1002.0	COG0318@1|root,COG3321@1|root,COG0318@2|Bacteria,COG3321@2|Bacteria,2H477@201174|Actinobacteria,232E7@1762|Mycobacteriaceae	201174|Actinobacteria	Q	polyketide synthase	-	-	2.3.1.165	ko:K12441,ko:K12443,ko:K15320,ko:K21792	ko00333,ko01059,ko01130,map00333,map01059,map01130	M00829,M00838	R07253,R11664	RC00004	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	-	-	-	ADH_N,ADH_zinc_N,AMP-binding,Acyl_transf_1,Aminotran_1_2,Aminotran_3,Condensation,Epimerase,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
CH3_k127_2896357_2	1173028.ANKO01000220_gene563	3.767e-205	657.0	COG0236@1|root,COG0318@1|root,COG0236@2|Bacteria,COG0318@2|Bacteria,1G4CE@1117|Cyanobacteria,1HHT8@1150|Oscillatoriales	1117|Cyanobacteria	IQ	AMP-dependent synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,PP-binding,Thioesterase
CH3_k127_2896357_4	1382306.JNIM01000001_gene377	5.548e-44	167.0	COG2185@1|root,COG2185@2|Bacteria,2G6S9@200795|Chloroflexi	200795|Chloroflexi	I	PFAM cobalamin B12-binding domain protein	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
CH3_k127_2896357_1	1123405.AUMM01000010_gene1224	2.338e-214	676.0	COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,4H9QB@91061|Bacilli,26P9A@186821|Sporolactobacillaceae	91061|Bacilli	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
CH3_k127_2896357_3	391623.TERMP_01057	2.506e-44	164.0	COG0346@1|root,arCOG02706@2157|Archaea,2XY0R@28890|Euryarchaeota,24458@183968|Thermococci	183968|Thermococci	E	Glyoxalase-like domain	-	GO:0003674,GO:0003824,GO:0004493,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016853,GO:0016854,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046491,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
CH3_k127_2896357_7	522306.CAP2UW1_0407	4.41e-05	51.0	COG5433@1|root,COG5433@2|Bacteria,1MXB5@1224|Proteobacteria,2VMZ8@28216|Betaproteobacteria	28216|Betaproteobacteria	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
CH3_k127_2896357_5	1340493.JNIF01000003_gene2050	1.225e-28	122.0	COG3436@1|root,COG3436@2|Bacteria	2|Bacteria	L	PFAM IS66 Orf2 family protein	tnpB	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	TnpB_IS66
CH3_k127_2896357_6	1128421.JAGA01000003_gene2773	8.496e-17	88.0	COG1109@1|root,COG1109@2|Bacteria,2NNTH@2323|unclassified Bacteria	2|Bacteria	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	femD	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
CH3_k127_292659_4	1210884.HG799470_gene14506	0.0007487	45.0	COG0584@1|root,COG0584@2|Bacteria,2J1MH@203682|Planctomycetes	203682|Planctomycetes	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
CH3_k127_292659_1	1158292.JPOE01000002_gene3555	1.26e-102	343.0	COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria,2VHIR@28216|Betaproteobacteria,1KMXP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	Subunit R is required for both nuclease and ATPase activities, but not for modification	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
CH3_k127_292659_2	761193.Runsl_4067	1.404e-67	240.0	COG1082@1|root,COG1082@2|Bacteria,4NFS5@976|Bacteroidetes,47NAA@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	5.1.3.22	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R03244	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	AP_endonuc_2
CH3_k127_292659_0	886293.Sinac_6980	6.133e-150	489.0	COG0673@1|root,COG0673@2|Bacteria,2IWX9@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CH3_k127_292659_3	234267.Acid_6615	3.081e-18	94.0	28KX8@1|root,2ZAD8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_2928921_2	309799.DICTH_0179	6.476e-67	237.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	ko:K20952	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Beta-prism_lec,PQQ_2,PQQ_3,Pkinase,VCBS
CH3_k127_2928921_4	215803.DB30_7465	1.149e-40	156.0	2E69S@1|root,330XP@2|Bacteria,1N7XM@1224|Proteobacteria	1224|Proteobacteria	S	Lipocalin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Lipocalin_5
CH3_k127_2928921_3	497964.CfE428DRAFT_3476	1.206e-56	215.0	COG0457@1|root,COG0457@2|Bacteria,46TQ7@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
CH3_k127_2928921_1	765420.OSCT_1304	3.682e-80	276.0	COG0157@1|root,COG0157@2|Bacteria,2G6GJ@200795|Chloroflexi,375H1@32061|Chloroflexia	32061|Chloroflexia	H	Belongs to the NadC ModD family	-	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
CH3_k127_2928921_0	1232410.KI421415_gene2957	1.027e-80	279.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1MWCC@1224|Proteobacteria,42P6I@68525|delta/epsilon subdivisions,2WMAF@28221|Deltaproteobacteria,43S1Q@69541|Desulfuromonadales	28221|Deltaproteobacteria	HK	HTH domain	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
CH3_k127_2930804_12	497964.CfE428DRAFT_0145	2.715e-13	74.0	COG4826@1|root,COG4826@2|Bacteria,46VTK@74201|Verrucomicrobia	74201|Verrucomicrobia	O	SERine  Proteinase INhibitors	-	-	-	-	-	-	-	-	-	-	-	-	Serpin
CH3_k127_2930804_7	1907.SGLAU_26935	8.303e-49	179.0	COG3509@1|root,COG3693@1|root,COG3509@2|Bacteria,COG3693@2|Bacteria,2GJSN@201174|Actinobacteria	201174|Actinobacteria	G	PFAM glycoside hydrolase, family 10	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,Glyco_hydro_10,Glyco_hydro_62,RicinB_lectin_2
CH3_k127_2930804_11	285535.JOEY01000051_gene1463	5.382e-25	111.0	COG3693@1|root,COG3693@2|Bacteria,2GJSN@201174|Actinobacteria	201174|Actinobacteria	G	PFAM glycoside hydrolase, family 10	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,Glyco_hydro_10,Glyco_hydro_62,RicinB_lectin_2
CH3_k127_2930804_3	1403819.BATR01000171_gene5859	1.671e-163	526.0	COG0265@1|root,COG0750@1|root,COG0265@2|Bacteria,COG0750@2|Bacteria	2|Bacteria	M	metalloendopeptidase activity	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
CH3_k127_2930804_6	351160.RRC213	2.28e-66	262.0	COG3391@1|root,arCOG02544@1|root,arCOG02544@2157|Archaea,arCOG02562@2157|Archaea,2Y7T2@28890|Euryarchaeota,2NBM7@224756|Methanomicrobia	224756|Methanomicrobia	S	Lactonase, 7-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
CH3_k127_2930804_14	879243.Poras_0890	2.81e-10	76.0	COG3630@1|root,COG3630@2|Bacteria,4NIHN@976|Bacteroidetes,2FMSV@200643|Bacteroidia,22W1S@171551|Porphyromonadaceae	976|Bacteroidetes	C	Oxaloacetate decarboxylase, gamma chain	-	-	-	-	-	-	-	-	-	-	-	-	LTD,OAD_gamma
CH3_k127_2930804_5	1396141.BATP01000043_gene1929	1.121e-108	402.0	COG5337@1|root,COG5337@2|Bacteria,46ZJW@74201|Verrucomicrobia,2IVD0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
CH3_k127_2930804_8	1396418.BATQ01000091_gene5770	2.339e-46	196.0	COG2273@1|root,COG2755@1|root,COG3064@1|root,COG3204@1|root,COG3291@1|root,COG2273@2|Bacteria,COG2755@2|Bacteria,COG3064@2|Bacteria,COG3204@2|Bacteria,COG3291@2|Bacteria,46X9M@74201|Verrucomicrobia,2IV4C@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EGM	Peptidase M60-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,M60-like_N,PA14,Peptidase_M60
CH3_k127_2930804_4	240016.ABIZ01000001_gene5895	3.478e-130	419.0	COG2133@1|root,COG2133@2|Bacteria,46ZKI@74201|Verrucomicrobia,2IVI9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CH3_k127_2930804_2	521674.Plim_3206	6.813e-192	617.0	COG3119@1|root,COG3119@2|Bacteria,2IXXP@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.13	ko:K01136	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00076,M00078	R07812,R07821	-	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4976,Sulfatase
CH3_k127_2930804_13	240016.ABIZ01000001_gene2135	5.295e-12	67.0	COG0583@1|root,COG0583@2|Bacteria,46TNE@74201|Verrucomicrobia,2IUPD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CH3_k127_2930804_0	748280.NH8B_1377	0.0	1293.0	COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,2VH5H@28216|Betaproteobacteria,2KQCR@206351|Neisseriales	206351|Neisseriales	C	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
CH3_k127_2930804_9	1121878.AUGL01000017_gene1759	1.05e-44	168.0	2CWKB@1|root,32SZW@2|Bacteria,1RD54@1224|Proteobacteria,1S4QG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_2930804_1	1166018.FAES_1357	6.276e-224	702.0	COG0673@1|root,COG0673@2|Bacteria,4NDYI@976|Bacteroidetes,47N60@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C,TAT_signal
CH3_k127_2930804_10	1210884.HG799462_gene7872	2.565e-43	165.0	COG0095@1|root,COG0095@2|Bacteria,2J0D8@203682|Planctomycetes	203682|Planctomycetes	H	PFAM Biotin lipoate A B protein ligase	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
CH3_k127_2936333_7	497964.CfE428DRAFT_4081	2.216e-115	387.0	COG1063@1|root,COG1063@2|Bacteria,46UMA@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate	tdh	-	1.1.1.103	ko:K00060	ko00260,map00260	-	R01465	RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CH3_k127_2936333_10	1396418.BATQ01000026_gene5273	5.327e-82	277.0	COG1476@1|root,COG1917@1|root,COG1476@2|Bacteria,COG1917@2|Bacteria,46TBZ@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_19
CH3_k127_2936333_13	886293.Sinac_3116	9.049e-12	75.0	COG2165@1|root,COG2165@2|Bacteria,2IZ6K@203682|Planctomycetes	203682|Planctomycetes	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CH3_k127_2936333_1	1403819.BATR01000087_gene2529	3.143e-231	720.0	COG2873@1|root,COG2873@2|Bacteria,46TEJ@74201|Verrucomicrobia,2ITJ5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
CH3_k127_2936333_5	102129.Lepto7375DRAFT_2106	1.994e-136	444.0	COG2021@1|root,COG2021@2|Bacteria,1G4G5@1117|Cyanobacteria,1HHP2@1150|Oscillatoriales	1117|Cyanobacteria	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metXA	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
CH3_k127_2936333_11	452637.Oter_0095	4.967e-68	253.0	COG4942@1|root,COG4942@2|Bacteria,46U5A@74201|Verrucomicrobia,3K7T2@414999|Opitutae	414999|Opitutae	D	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_2936333_12	452637.Oter_0096	5.471e-64	241.0	2EWFD@1|root,33PTV@2|Bacteria,46UNG@74201|Verrucomicrobia,3K7NI@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_2936333_3	1396418.BATQ01000078_gene594	4.308e-169	539.0	COG0577@1|root,COG0577@2|Bacteria,46UQN@74201|Verrucomicrobia,2IVBP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
CH3_k127_2936333_4	1403819.BATR01000150_gene5077	7.079e-155	499.0	COG0577@1|root,COG0577@2|Bacteria,46UT6@74201|Verrucomicrobia,2IVGX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
CH3_k127_2936333_8	452637.Oter_1514	1.185e-114	376.0	COG1136@1|root,COG1136@2|Bacteria,46YZ8@74201|Verrucomicrobia,3K9FX@414999|Opitutae	414999|Opitutae	P	PFAM ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CH3_k127_2936333_6	1396418.BATQ01000078_gene597	3.093e-129	424.0	COG0845@1|root,COG0845@2|Bacteria,46UZZ@74201|Verrucomicrobia,2IVAY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
CH3_k127_2936333_0	452637.Oter_4609	1.578e-306	959.0	COG1297@1|root,COG1297@2|Bacteria	2|Bacteria	S	iron-nicotianamine transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	OPT
CH3_k127_2936333_2	1121920.AUAU01000007_gene416	2.14e-185	598.0	COG1164@1|root,COG1164@2|Bacteria,3Y2SB@57723|Acidobacteria	57723|Acidobacteria	E	Angiotensin-converting enzyme	-	-	3.4.15.1	ko:K01283	ko04614,ko04924,ko05142,ko05410,map04614,map04924,map05142,map05410	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	Peptidase_M2
CH3_k127_2936333_9	278957.ABEA03000206_gene3779	2.006e-101	336.0	COG0379@1|root,COG0379@2|Bacteria,46SA1@74201|Verrucomicrobia,3K7P4@414999|Opitutae	414999|Opitutae	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
CH3_k127_2941808_4	1286631.X805_30960	1.568e-52	208.0	COG1404@1|root,COG1520@1|root,COG5640@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,COG5640@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	ko:K14645,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	PPC,PQQ_2,Peptidase_S8,SBBP
CH3_k127_2941808_9	1408254.T458_02935	1.421e-20	103.0	COG4244@1|root,COG4244@2|Bacteria,1UHFB@1239|Firmicutes,4HCQT@91061|Bacilli,26UEU@186822|Paenibacillaceae	91061|Bacilli	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_2941808_2	452637.Oter_3700	1.69e-101	339.0	COG3568@1|root,COG3568@2|Bacteria	2|Bacteria	N	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CH3_k127_2941808_6	1115632.JAFW01000001_gene36	4.326e-42	165.0	COG0566@1|root,COG0566@2|Bacteria,2GJ12@201174|Actinobacteria,1W83K@1268|Micrococcaceae	201174|Actinobacteria	J	SpoU rRNA Methylase family	spoU2	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
CH3_k127_2941808_1	1210884.HG799462_gene8336	3.715e-111	375.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CH3_k127_2941808_7	1192034.CAP_8755	1.289e-33	136.0	COG0782@1|root,COG0782@2|Bacteria,1RAP0@1224|Proteobacteria,42UCT@68525|delta/epsilon subdivisions,2WPAW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus	greB	-	-	ko:K04760	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
CH3_k127_2941808_3	497964.CfE428DRAFT_6105	3.762e-75	263.0	COG1235@1|root,COG1235@2|Bacteria,46SKU@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
CH3_k127_2941808_0	497964.CfE428DRAFT_2602	1.48e-155	507.0	COG1508@1|root,COG1508@2|Bacteria,46SDZ@74201|Verrucomicrobia	74201|Verrucomicrobia	K	TIGRFAM RNA polymerase sigma-54 factor, RpoN	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
CH3_k127_2941808_5	1210884.HG799464_gene11269	2.315e-42	157.0	COG0681@1|root,COG0681@2|Bacteria,2J14X@203682|Planctomycetes	203682|Planctomycetes	U	Belongs to the peptidase S26 family	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_2941808_8	1123508.JH636440_gene2840	3.193e-30	121.0	COG3391@1|root,COG3391@2|Bacteria,2IY6R@203682|Planctomycetes	203682|Planctomycetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_2958005_3	192952.MM_3371	1.194e-55	207.0	arCOG06820@1|root,arCOG06820@2157|Archaea,2XVYD@28890|Euryarchaeota,2N917@224756|Methanomicrobia	224756|Methanomicrobia	S	YoaP-like	-	-	-	-	-	-	-	-	-	-	-	-	YoaP
CH3_k127_2958005_0	886293.Sinac_0736	1.589e-190	628.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,2IYAH@203682|Planctomycetes	203682|Planctomycetes	C	FAD linked oxidases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17,Fer4_8
CH3_k127_2958005_1	1185876.BN8_06038	2.14e-105	352.0	COG1082@1|root,COG1082@2|Bacteria,4NGKX@976|Bacteroidetes,47JP9@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CH3_k127_2958005_2	240016.ABIZ01000001_gene1588	2.457e-89	310.0	COG0673@1|root,COG0673@2|Bacteria,46TM9@74201|Verrucomicrobia,2ITZ3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CH3_k127_2958005_5	395495.Lcho_0773	4.098e-05	46.0	COG3335@1|root,COG3335@2|Bacteria,1N5WI@1224|Proteobacteria,2VHUB@28216|Betaproteobacteria,1KPAP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
CH3_k127_2995849_14	283942.IL2026	9.226e-06	56.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,1RPJS@1236|Gammaproteobacteria,2QEZ9@267893|Idiomarinaceae	1236|Gammaproteobacteria	NU	general secretion pathway protein	gspD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
CH3_k127_2995849_7	661478.OP10G_4206	2.64e-46	183.0	COG1450@1|root,COG1450@2|Bacteria	2|Bacteria	NU	protein transport across the cell outer membrane	gspD	-	-	ko:K02453,ko:K03219	ko03070,ko05111,map03070,map05111	M00331,M00332,M00542	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15,3.A.6.1,3.A.6.3	-	-	Secretin,Secretin_N
CH3_k127_2995849_9	644282.Deba_1655	2.602e-40	168.0	COG3852@1|root,COG3852@2|Bacteria,1RCUD@1224|Proteobacteria,42R9I@68525|delta/epsilon subdivisions,2WN53@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
CH3_k127_2995849_6	1304885.AUEY01000116_gene2847	1.762e-123	410.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M2X@68525|delta/epsilon subdivisions,2WJMY@28221|Deltaproteobacteria,2MIYR@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
CH3_k127_2995849_3	349741.Amuc_2115	2.388e-138	452.0	COG0172@1|root,COG0172@2|Bacteria,46S70@74201|Verrucomicrobia,2ITV1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Seryl-tRNA synthetase N-terminal domain	-	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
CH3_k127_2995849_4	404589.Anae109_0139	5.142e-132	436.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,42MT8@68525|delta/epsilon subdivisions,2WITI@28221|Deltaproteobacteria,2YU1G@29|Myxococcales	28221|Deltaproteobacteria	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
CH3_k127_2995849_8	1156937.MFUM_300024	3.094e-46	184.0	COG0681@1|root,COG0681@2|Bacteria,46SR0@74201|Verrucomicrobia,37FWK@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	U	Signal peptidase, peptidase S26	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
CH3_k127_2995849_1	1051632.TPY_0699	1.023e-223	707.0	COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,247V8@186801|Clostridia,3WCEY@538999|Clostridiales incertae sedis	186801|Clostridia	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
CH3_k127_2995849_2	497964.CfE428DRAFT_3344	1.001e-222	718.0	COG1204@1|root,COG1204@2|Bacteria,46SCW@74201|Verrucomicrobia	74201|Verrucomicrobia	L	DEAD DEAH box helicase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
CH3_k127_2995849_0	497964.CfE428DRAFT_3556	3.817e-286	895.0	COG1185@1|root,COG1185@2|Bacteria,46SBP@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
CH3_k127_2995849_10	273068.TTE1388	1.41e-26	110.0	COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,24MRM@186801|Clostridia,42GTG@68295|Thermoanaerobacterales	186801|Clostridia	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
CH3_k127_2995849_5	1396141.BATP01000003_gene4934	2.196e-126	458.0	COG2312@1|root,COG2312@2|Bacteria	2|Bacteria	S	response to antibiotic	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Erythro_esteras,LTD
CH3_k127_2995849_12	1303518.CCALI_00044	7.296e-15	85.0	COG4537@1|root,COG4537@2|Bacteria	2|Bacteria	U	Required for transformation and DNA binding	comGC	GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944	-	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	M00331,M00429	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
CH3_k127_2995849_15	1038869.AXAN01000074_gene4073	0.000622	54.0	COG3250@1|root,COG3250@2|Bacteria,1QZHW@1224|Proteobacteria,2WI8K@28216|Betaproteobacteria,1KIR6@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Domain of unknown function (DUF4982)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4982,F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_64,I-set,Ig_3
CH3_k127_2995849_13	378806.STAUR_1759	4.673e-12	81.0	COG3250@1|root,COG3250@2|Bacteria,1QZHW@1224|Proteobacteria	1224|Proteobacteria	G	Domain of unknown function (DUF4982)	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	DUF4982,F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_64,I-set,Ig_3
CH3_k127_2995849_11	1123274.KB899414_gene3605	1.765e-25	109.0	COG2199@1|root,COG4251@1|root,COG3706@2|Bacteria,COG4251@2|Bacteria,2JAW9@203691|Spirochaetes	203691|Spirochaetes	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
CH3_k127_3023717_2	582899.Hden_1369	0.0005392	52.0	COG3408@1|root,COG3408@2|Bacteria,1MUYU@1224|Proteobacteria,2TQK2@28211|Alphaproteobacteria,3N7PF@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	G	N-terminal domain of (some) glycogen debranching enzymes	MA20_17380	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H,GDE_C,GDE_N_bis
CH3_k127_3023717_0	497964.CfE428DRAFT_4864	1.154e-55	210.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_3023717_1	886293.Sinac_1051	1.463e-12	72.0	COG0515@1|root,COG0515@2|Bacteria,2IY6U@203682|Planctomycetes	203682|Planctomycetes	KLT	COG0515 Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CH3_k127_3039176_1	452637.Oter_1518	1.817e-102	346.0	2BYUR@1|root,32TV8@2|Bacteria,46V5C@74201|Verrucomicrobia,3K7PA@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_3039176_6	234267.Acid_7793	6.379e-24	103.0	COG1598@1|root,COG1598@2|Bacteria,3Y5U6@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_3039176_8	13035.Dacsa_0245	7.747e-17	81.0	COG1724@1|root,COG1724@2|Bacteria,1G8WI@1117|Cyanobacteria	1117|Cyanobacteria	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
CH3_k127_3039176_7	926569.ANT_11850	5.984e-20	95.0	COG0784@1|root,COG0784@2|Bacteria,2GBNB@200795|Chloroflexi	200795|Chloroflexi	T	cheY-homologous receiver domain	-	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
CH3_k127_3039176_2	583355.Caka_0017	1.948e-82	281.0	COG3880@1|root,COG3880@2|Bacteria,46SMN@74201|Verrucomicrobia,3K7MX@414999|Opitutae	414999|Opitutae	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII,Cytochrome_C7
CH3_k127_3039176_0	452637.Oter_3934	0.0	1032.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,46S66@74201|Verrucomicrobia,3K7GM@414999|Opitutae	414999|Opitutae	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7
CH3_k127_3039176_4	278957.ABEA03000189_gene958	7.049e-25	106.0	COG5557@1|root,COG5557@2|Bacteria,46S9S@74201|Verrucomicrobia,3K751@414999|Opitutae	414999|Opitutae	C	Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
CH3_k127_3041063_0	1403819.BATR01000019_gene632	5.527e-80	271.0	COG3576@1|root,COG3576@2|Bacteria,46SQM@74201|Verrucomicrobia,2IVR9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
CH3_k127_3041063_1	240016.ABIZ01000001_gene199	2.431e-76	258.0	COG3558@1|root,COG3558@2|Bacteria,46SSI@74201|Verrucomicrobia,2IUG3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF1348)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1348
CH3_k127_3041063_4	1121877.JQKF01000016_gene173	6.207e-07	59.0	COG5433@1|root,COG5433@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
CH3_k127_3041063_2	555779.Dthio_PD3188	2.618e-52	202.0	COG5433@1|root,COG5433@2|Bacteria,1MXB5@1224|Proteobacteria,431TI@68525|delta/epsilon subdivisions,2WWAP@28221|Deltaproteobacteria,2MB98@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	DDE_Tnp_1-associated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc,DUF4338
CH3_k127_3041063_3	326427.Cagg_3284	1.061e-09	64.0	COG5295@1|root,COG5295@2|Bacteria	2|Bacteria	UW	Hep Hag repeat protein	-	-	-	ko:K11904,ko:K21449	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	1.B.40.2,3.A.23.1	-	-	Peptidase_S74,Phage_GPD,YadA_anchor,YadA_head,YadA_stalk
CH3_k127_3046811_2	913865.DOT_3234	3.063e-12	82.0	COG0613@1|root,COG0737@1|root,COG1409@1|root,COG3204@1|root,COG3211@1|root,COG4733@1|root,COG0613@2|Bacteria,COG0737@2|Bacteria,COG1409@2|Bacteria,COG3204@2|Bacteria,COG3211@2|Bacteria,COG4733@2|Bacteria,1TSSR@1239|Firmicutes,248DJ@186801|Clostridia	186801|Clostridia	O	PFAM Metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,Metallophos,Pur_ac_phosph_N,SLH
CH3_k127_3046811_0	583355.Caka_1736	0.0	1087.0	COG2312@1|root,COG2312@2|Bacteria,46TMX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
CH3_k127_3046811_1	1210884.HG799465_gene12283	1.609e-154	499.0	COG0542@1|root,COG0542@2|Bacteria,2IWYZ@203682|Planctomycetes	203682|Planctomycetes	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
CH3_k127_3076863_4	1131269.AQVV01000053_gene213	1.979e-20	96.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1,OEP
CH3_k127_3076863_3	1232437.KL662020_gene700	7.258e-80	290.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,42PAC@68525|delta/epsilon subdivisions,2WKAD@28221|Deltaproteobacteria,2MMGU@213118|Desulfobacterales	28221|Deltaproteobacteria	M	HlyD membrane-fusion protein of T1SS	-	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
CH3_k127_3076863_2	530564.Psta_4732	1.498e-83	286.0	COG1136@1|root,COG1136@2|Bacteria,2IY81@203682|Planctomycetes	203682|Planctomycetes	V	ABC-type antimicrobial peptide transport system, ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CH3_k127_3076863_0	886293.Sinac_4798	2.889e-119	398.0	COG0577@1|root,COG0577@2|Bacteria,2IX11@203682|Planctomycetes	203682|Planctomycetes	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CH3_k127_3076863_1	1123070.KB899249_gene294	1.067e-98	337.0	COG1331@1|root,COG1331@2|Bacteria,46SEJ@74201|Verrucomicrobia,2ITZQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredox_DsbH
CH3_k127_309195_4	1396141.BATP01000007_gene5570	3.563e-112	395.0	COG5306@1|root,COG5306@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
CH3_k127_309195_14	794903.OPIT5_08425	3.516e-13	80.0	COG4968@1|root,COG4968@2|Bacteria,46YJJ@74201|Verrucomicrobia,3K9QQ@414999|Opitutae	414999|Opitutae	NU	Prepilin-type N-terminal cleavage methylation domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_309195_16	1297617.JPJD01000023_gene1562	0.0001245	54.0	COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,248HZ@186801|Clostridia,267R3@186813|unclassified Clostridiales	186801|Clostridia	M	tail specific protease	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
CH3_k127_309195_11	1396141.BATP01000023_gene616	1.386e-47	180.0	2B5SN@1|root,31YNB@2|Bacteria,46XHC@74201|Verrucomicrobia,2IVXC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_309195_10	382464.ABSI01000020_gene153	1.652e-51	190.0	COG2194@1|root,COG2194@2|Bacteria,46XHR@74201|Verrucomicrobia,2IVYD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	sulfuric ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_309195_2	293826.Amet_3280	3.413e-182	581.0	COG1032@1|root,COG1032@2|Bacteria,1UYAF@1239|Firmicutes,24D1D@186801|Clostridia,36F9T@31979|Clostridiaceae	186801|Clostridia	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
CH3_k127_309195_12	706587.Desti_0559	8.246e-35	143.0	COG1225@1|root,COG1225@2|Bacteria,1NZF4@1224|Proteobacteria,42ZRX@68525|delta/epsilon subdivisions	1224|Proteobacteria	O	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_309195_1	234267.Acid_7735	7.566e-222	699.0	COG1032@1|root,COG1032@2|Bacteria,3Y4FB@57723|Acidobacteria	57723|Acidobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
CH3_k127_309195_7	1396418.BATQ01000107_gene5393	6.506e-71	248.0	COG1633@1|root,COG1633@2|Bacteria,46VFF@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_309195_6	497964.CfE428DRAFT_2012	8.805e-74	260.0	COG0761@1|root,COG0761@2|Bacteria,46SYM@74201|Verrucomicrobia	74201|Verrucomicrobia	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
CH3_k127_309195_13	1340493.JNIF01000003_gene1913	2.072e-26	111.0	COG1846@1|root,COG1846@2|Bacteria,3Y7YY@57723|Acidobacteria	57723|Acidobacteria	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_34
CH3_k127_309195_15	240016.ABIZ01000001_gene4454	3.381e-10	68.0	2BJXT@1|root,32EAA@2|Bacteria,46XIQ@74201|Verrucomicrobia,2IW0S@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_309195_5	485913.Krac_6798	6.43e-84	295.0	COG0604@1|root,COG0604@2|Bacteria,2G6DS@200795|Chloroflexi	200795|Chloroflexi	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
CH3_k127_309195_0	497964.CfE428DRAFT_0484	0.0	1022.0	COG0480@1|root,COG0480@2|Bacteria,46SFV@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
CH3_k127_309195_9	452637.Oter_0229	4.895e-56	199.0	COG0049@1|root,COG0049@2|Bacteria,46UH0@74201|Verrucomicrobia,3K7QA@414999|Opitutae	414999|Opitutae	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
CH3_k127_309195_8	794903.OPIT5_02450	1.155e-65	226.0	COG0048@1|root,COG0048@2|Bacteria,46SQR@74201|Verrucomicrobia,3K7YQ@414999|Opitutae	414999|Opitutae	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
CH3_k127_309195_3	497964.CfE428DRAFT_5595	8.95e-135	434.0	COG0086@1|root,COG0086@2|Bacteria,46S79@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
CH3_k127_3093675_0	886293.Sinac_6493	1.559e-144	482.0	COG0501@1|root,COG0501@2|Bacteria,2IYND@203682|Planctomycetes	203682|Planctomycetes	O	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
CH3_k127_3093675_2	999419.HMPREF1077_03046	1.236e-35	149.0	COG2303@1|root,COG2303@2|Bacteria,4PKTW@976|Bacteroidetes,2FS8M@200643|Bacteroidia,22XM0@171551|Porphyromonadaceae	976|Bacteroidetes	E	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CH3_k127_3093675_1	1403819.BATR01000120_gene4250	5.265e-95	327.0	COG0477@1|root,COG2814@2|Bacteria,46V8K@74201|Verrucomicrobia,2IUV3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EGP	Nucleoside H+ symporter	-	-	-	-	-	-	-	-	-	-	-	-	Nuc_H_symport
CH3_k127_3142209_2	452637.Oter_3559	4.07e-141	457.0	COG1070@1|root,COG1070@2|Bacteria,46SI1@74201|Verrucomicrobia,3K7BT@414999|Opitutae	414999|Opitutae	G	FGGY family of carbohydrate kinases, C-terminal domain	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
CH3_k127_3142209_9	1210884.HG799462_gene9284	1.205e-80	277.0	COG0584@1|root,COG0584@2|Bacteria,2IYVE@203682|Planctomycetes	203682|Planctomycetes	C	Glycerophosphoryl diester phosphodiesterase family	-	-	-	-	-	-	-	-	-	-	-	-	GDPD_2
CH3_k127_3142209_16	794903.OPIT5_09565	1.575e-07	62.0	COG4969@1|root,COG4969@2|Bacteria,46YC2@74201|Verrucomicrobia,3K9A9@414999|Opitutae	414999|Opitutae	NU	Belongs to the N-Me-Phe pilin family	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_3142209_4	251221.35213668	9.442e-101	340.0	COG1680@1|root,COG1680@2|Bacteria,1G737@1117|Cyanobacteria	1117|Cyanobacteria	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CH3_k127_3142209_13	661478.OP10G_3764	8.969e-14	81.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02650,ko:K02679	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10
CH3_k127_3142209_1	497964.CfE428DRAFT_2042	3.136e-155	495.0	COG1087@1|root,COG1087@2|Bacteria,46SIR@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
CH3_k127_3142209_10	1121918.ARWE01000001_gene1522	1.224e-47	175.0	COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,42RJX@68525|delta/epsilon subdivisions,2WQNR@28221|Deltaproteobacteria,43W09@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	SpoU rRNA Methylase family	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
CH3_k127_3142209_5	1396141.BATP01000027_gene1172	7.497e-98	327.0	COG0101@1|root,COG0101@2|Bacteria,46SSV@74201|Verrucomicrobia,2IU7R@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	-	-	-	-	-	-	-	-	-	-	-	-	PseudoU_synth_1
CH3_k127_3142209_11	478741.JAFS01000002_gene271	3.019e-40	154.0	COG0816@1|root,COG0816@2|Bacteria,46T51@74201|Verrucomicrobia,37GTE@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	rnhD	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
CH3_k127_3142209_14	1410613.JNKF01000011_gene1093	7.464e-10	67.0	COG1925@1|root,COG1925@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	-	-	2.7.1.121	ko:K05881	ko00561,map00561	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS-HPr
CH3_k127_3142209_0	497964.CfE428DRAFT_1556	1.033e-169	546.0	COG0001@1|root,COG0001@2|Bacteria,46S67@74201|Verrucomicrobia	74201|Verrucomicrobia	H	intramolecular transferase activity, transferring amino groups	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CH3_k127_3142209_8	945713.IALB_0521	2.487e-82	278.0	COG4627@1|root,COG4627@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	BON,Glycos_transf_2,Methyltransf_11
CH3_k127_3142209_6	1396418.BATQ01000067_gene1728	6.707e-92	308.0	COG1028@1|root,COG1028@2|Bacteria,46SNA@74201|Verrucomicrobia,2ITSE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CH3_k127_3142209_7	1123070.KB899253_gene1115	1.281e-84	290.0	COG0331@1|root,COG0331@2|Bacteria,46SNS@74201|Verrucomicrobia,2ITTM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Acyl transferase domain	-	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
CH3_k127_3142209_12	1173027.Mic7113_2682	3.143e-23	111.0	COG4886@1|root,COG4886@2|Bacteria,1G05B@1117|Cyanobacteria,1H6Y6@1150|Oscillatoriales	1117|Cyanobacteria	S	COG4886 Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	COR,LRR_4,LRR_8,Roc
CH3_k127_3142209_15	314345.SPV1_00987	1.062e-07	60.0	2DPGY@1|root,3320R@2|Bacteria,1ND7F@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF3185)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3185
CH3_k127_3142209_3	1123393.KB891317_gene2207	3.745e-104	346.0	COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,2VQ9J@28216|Betaproteobacteria,1KSDQ@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Conserved TM helix	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel,TM_helix
CH3_k127_3142209_17	452637.Oter_1161	7.509e-07	53.0	COG4575@1|root,COG4575@2|Bacteria,46WFC@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Bacterial protein of unknown function (DUF883)	-	-	-	-	-	-	-	-	-	-	-	-	DUF883
CH3_k127_3148141_3	56110.Oscil6304_2123	1.911e-26	127.0	COG2931@1|root,COG2931@2|Bacteria,1G4IS@1117|Cyanobacteria,1HAFZ@1150|Oscillatoriales	1117|Cyanobacteria	Q	RTX toxins and related Ca2 binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,HemolysinCabind
CH3_k127_3148141_1	449447.MAE_29050	1.566e-48	199.0	COG1621@1|root,COG2931@1|root,COG1621@2|Bacteria,COG2931@2|Bacteria,1G32M@1117|Cyanobacteria	1117|Cyanobacteria	Q	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	PPC,VCBS
CH3_k127_3148141_2	1123399.AQVE01000001_gene684	3.635e-48	184.0	COG3291@1|root,COG5295@1|root,COG3291@2|Bacteria,COG5295@2|Bacteria,1RGWM@1224|Proteobacteria,1SKIX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	UW	Metallo-peptidase family M12B Reprolysin-like	-	-	-	-	-	-	-	-	-	-	-	-	Reprolysin_3
CH3_k127_3148141_0	1380394.JADL01000003_gene4962	1.684e-213	690.0	COG1216@1|root,COG3934@1|root,COG1216@2|Bacteria,COG3934@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9,Cellulase,Glyco_hydro_2_C,Glycos_transf_2
CH3_k127_3149204_1	1469607.KK073768_gene2490	0.0005614	53.0	COG1404@1|root,COG2931@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF4214,Peptidase_S8
CH3_k127_3149204_0	497964.CfE428DRAFT_4839	2.198e-78	269.0	COG0568@1|root,COG0568@2|Bacteria,46SJ8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
CH3_k127_3166335_40	771875.Ferpe_0574	4.162e-11	69.0	COG1520@1|root,COG1520@2|Bacteria,2GCVR@200918|Thermotogae	200918|Thermotogae	F	PFAM PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
CH3_k127_3166335_2	313624.NSP_23270	1.167e-176	559.0	COG0451@1|root,COG0451@2|Bacteria,1G0IT@1117|Cyanobacteria,1HM8T@1161|Nostocales	1117|Cyanobacteria	M	Male sterility protein	-	-	5.1.3.10	ko:K12454	ko00520,map00520	-	R04266	RC00528	ko00000,ko00001,ko01000	-	-	-	Epimerase
CH3_k127_3166335_7	452637.Oter_3990	1.134e-138	449.0	COG0451@1|root,COG0451@2|Bacteria,46TXA@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Male sterility protein	-	-	5.1.3.10	ko:K12454	ko00520,map00520	-	R04266	RC00528	ko00000,ko00001,ko01000	-	-	-	Epimerase
CH3_k127_3166335_44	1218076.BAYB01000008_gene1536	2.321e-06	60.0	COG2244@1|root,COG2244@2|Bacteria,1R6ME@1224|Proteobacteria,2VNGZ@28216|Betaproteobacteria,1K460@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Polysaccharide biosynthesis protein	rfbE	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
CH3_k127_3166335_42	491916.RHECIAT_CH0001616	1.18e-08	66.0	COG2227@1|root,COG2227@2|Bacteria,1RAQ6@1224|Proteobacteria,2U62S@28211|Alphaproteobacteria,4B9C2@82115|Rhizobiaceae	28211|Alphaproteobacteria	H	Methionine biosynthesis protein MetW	-	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_23
CH3_k127_3166335_38	1232410.KI421412_gene245	3.412e-13	81.0	COG0535@1|root,COG0535@2|Bacteria,1RG5U@1224|Proteobacteria,42RKR@68525|delta/epsilon subdivisions,2WNUX@28221|Deltaproteobacteria,43VVF@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
CH3_k127_3166335_35	326424.FRAAL2042	8.958e-17	90.0	COG2242@1|root,COG2242@2|Bacteria	2|Bacteria	H	protein methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
CH3_k127_3166335_20	595537.Varpa_3992	2.841e-61	219.0	COG4122@1|root,COG4122@2|Bacteria,1NR4H@1224|Proteobacteria	1224|Proteobacteria	H	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_3166335_30	690850.Desaf_2652	9.274e-27	124.0	COG0438@1|root,COG0438@2|Bacteria,1R9QG@1224|Proteobacteria,42PQQ@68525|delta/epsilon subdivisions,2WTQJ@28221|Deltaproteobacteria,2M9KJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
CH3_k127_3166335_48	491915.Aflv_2575	0.0001404	53.0	COG0457@1|root,COG0463@1|root,COG0457@2|Bacteria,COG0463@2|Bacteria,1TSF5@1239|Firmicutes,4HCKY@91061|Bacilli,21WRB@150247|Anoxybacillus	91061|Bacilli	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,TPR_16,TPR_8
CH3_k127_3166335_46	1246445.ANAY01000001_gene403	3.581e-05	56.0	COG0438@1|root,COG0438@2|Bacteria,2GNUU@201174|Actinobacteria,4EI9I@85012|Streptosporangiales	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
CH3_k127_3166335_25	521011.Mpal_2181	1.055e-38	154.0	COG0500@1|root,arCOG01789@2157|Archaea	2157|Archaea	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CH3_k127_3166335_31	926554.KI912668_gene5115	4.792e-22	108.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
CH3_k127_3166335_34	1396141.BATP01000035_gene4053	2.351e-17	96.0	29ZA9@1|root,30M8M@2|Bacteria,46XI8@74201|Verrucomicrobia,2IVZI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_3166335_27	497964.CfE428DRAFT_0276	3.098e-37	145.0	COG1959@1|root,COG1959@2|Bacteria,46SPI@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
CH3_k127_3166335_11	935567.JAES01000014_gene1558	2.902e-102	349.0	COG3746@1|root,COG3746@2|Bacteria,1R9AP@1224|Proteobacteria,1RS2N@1236|Gammaproteobacteria,1X2Z1@135614|Xanthomonadales	135614|Xanthomonadales	P	Phosphate-selective porin O and P	-	-	-	ko:K07221	-	-	-	-	ko00000,ko02000	1.B.5.1	-	-	Porin_O_P
CH3_k127_3166335_5	1122236.KB905142_gene569	2.493e-149	481.0	COG1613@1|root,COG1613@2|Bacteria,1MUAU@1224|Proteobacteria,2VIQZ@28216|Betaproteobacteria,2KKVC@206350|Nitrosomonadales	206350|Nitrosomonadales	P	TIGRFAM sulfate ABC transporter, periplasmic sulfate-binding protein	-	-	-	ko:K02048	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	SBP_bac_11
CH3_k127_3166335_10	640081.Dsui_0260	6.626e-112	370.0	COG0555@1|root,COG0555@2|Bacteria,1QTTU@1224|Proteobacteria,2VHKY@28216|Betaproteobacteria,2KV4D@206389|Rhodocyclales	206389|Rhodocyclales	P	Sulfate ABC transporter inner membrane subunit CysT	-	-	-	ko:K02046	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
CH3_k127_3166335_9	1121035.AUCH01000001_gene1959	1.902e-123	404.0	COG4208@1|root,COG4208@2|Bacteria,1MV8X@1224|Proteobacteria,2VI3S@28216|Betaproteobacteria,2KV49@206389|Rhodocyclales	206389|Rhodocyclales	P	Sulfate ABC transporter inner membrane subunit CysW	-	-	-	ko:K02047	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
CH3_k127_3166335_8	330214.NIDE1620	6.369e-136	441.0	COG1118@1|root,COG1118@2|Bacteria	2|Bacteria	P	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system	cysA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008144,GO:0008150,GO:0008272,GO:0008509,GO:0015075,GO:0015103,GO:0015116,GO:0015318,GO:0015399,GO:0015405,GO:0015419,GO:0015698,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034220,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043225,GO:0043492,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0072348,GO:0097159,GO:0097367,GO:0098656,GO:0098660,GO:0098661,GO:0099133,GO:1901265,GO:1901363,GO:1901682,GO:1902358	3.6.3.25,3.6.3.29	ko:K02017,ko:K02045,ko:K10112,ko:K16787	ko00920,ko02010,map00920,map02010	M00185,M00189,M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00582,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.1,3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35,3.A.1.6.1,3.A.1.6.3,3.A.1.8	-	iE2348C_1286.E2348C_2607,iSSON_1240.SSON_2511	ABC_tran,TOBE,TOBE_3
CH3_k127_3166335_1	234267.Acid_2664	7.265e-202	640.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,Cellulase,Lipase_GDSL_2,PA14,RicinB_lectin_2
CH3_k127_3166335_47	3694.POPTR_0006s25110.1	5.46e-05	55.0	2CN88@1|root,2QUFZ@2759|Eukaryota,37NST@33090|Viridiplantae,3GD0N@35493|Streptophyta,4JGBC@91835|fabids	35493|Streptophyta	S	glycine-rich protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_3166335_45	1123400.KB904788_gene192	1.41e-05	58.0	COG3266@1|root,COG3266@2|Bacteria,1R0CZ@1224|Proteobacteria	1224|Proteobacteria	I	PFAM Prenyltransferase squalene oxidase	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
CH3_k127_3166335_12	335543.Sfum_3489	4.984e-102	355.0	COG0715@1|root,COG2885@1|root,COG0715@2|Bacteria,COG2885@2|Bacteria,1QU25@1224|Proteobacteria,42YRH@68525|delta/epsilon subdivisions,2WUGB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	NMT1/THI5 like	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
CH3_k127_3166335_36	1238190.AMQY01000023_gene441	8.174e-15	86.0	COG2304@1|root,COG2304@2|Bacteria,1RGCN@1224|Proteobacteria,1S5GI@1236|Gammaproteobacteria,1XPSH@135619|Oceanospirillales	135619|Oceanospirillales	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
CH3_k127_3166335_22	1121403.AUCV01000010_gene1377	1.299e-50	199.0	COG2885@1|root,COG3221@1|root,COG2885@2|Bacteria,COG3221@2|Bacteria,1R687@1224|Proteobacteria,42ZCB@68525|delta/epsilon subdivisions,2WTSU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	MP	NMT1/THI5 like	-	-	-	-	-	-	-	-	-	-	-	-	NMT1,OmpA
CH3_k127_3166335_29	1120792.JAFV01000001_gene1790	8.432e-29	128.0	COG0715@1|root,COG0715@2|Bacteria,1MVJA@1224|Proteobacteria,2TTB8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
CH3_k127_3166335_24	316056.RPC_4535	3.657e-44	171.0	COG0600@1|root,COG0600@2|Bacteria,1MWDJ@1224|Proteobacteria,2TTR3@28211|Alphaproteobacteria,3JR5N@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
CH3_k127_3166335_21	349521.HCH_05416	3.573e-58	214.0	COG1116@1|root,COG1116@2|Bacteria,1MWZG@1224|Proteobacteria,1RN60@1236|Gammaproteobacteria,1XJ0F@135619|Oceanospirillales	135619|Oceanospirillales	P	ABC-type nitrate sulfonate bicarbonate transport system, ATPase component	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
CH3_k127_3166335_4	1142394.PSMK_04700	2.306e-167	545.0	COG0464@1|root,COG0464@2|Bacteria	2|Bacteria	O	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA,BCS1_N
CH3_k127_3166335_3	1121904.ARBP01000032_gene2006	1.218e-174	585.0	COG0507@1|root,COG1112@1|root,COG0507@2|Bacteria,COG1112@2|Bacteria,4NK1G@976|Bacteroidetes,47RDC@768503|Cytophagia	976|Bacteroidetes	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,DUF2726
CH3_k127_3166335_14	1123073.KB899241_gene3101	9.4e-83	283.0	COG1028@1|root,COG1028@2|Bacteria,1MURZ@1224|Proteobacteria,1RMUM@1236|Gammaproteobacteria,1XCBQ@135614|Xanthomonadales	135614|Xanthomonadales	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CH3_k127_3166335_23	391596.PBAL39_10776	2.852e-46	171.0	COG3254@1|root,COG3254@2|Bacteria,4NQQ9@976|Bacteroidetes,1ISZ2@117747|Sphingobacteriia	976|Bacteroidetes	G	L-rhamnose mutarotase	-	-	5.1.3.32	ko:K03534	-	-	R10819	RC00563	ko00000,ko01000	-	-	-	rhaM
CH3_k127_3166335_6	1492737.FEM08_10420	2.289e-141	469.0	COG4146@1|root,COG4146@2|Bacteria,4NE9S@976|Bacteroidetes,1IJTV@117743|Flavobacteriia,2NVD2@237|Flavobacterium	976|Bacteroidetes	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
CH3_k127_3166335_43	234267.Acid_3197	1.942e-08	56.0	COG1724@1|root,COG1724@2|Bacteria	2|Bacteria	N	mRNA binding	-	-	-	ko:K07339	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HicA_toxin
CH3_k127_3166335_17	360910.BAV2339	4.428e-76	271.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,2VHFU@28216|Betaproteobacteria,3T1SB@506|Alcaligenaceae	28216|Betaproteobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CH3_k127_3166335_28	1192034.CAP_7227	5.83e-37	153.0	COG1434@1|root,COG1434@2|Bacteria,1NDJM@1224|Proteobacteria,42XJW@68525|delta/epsilon subdivisions,2WSJ3@28221|Deltaproteobacteria,2YVV6@29|Myxococcales	28221|Deltaproteobacteria	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
CH3_k127_3166335_15	452637.Oter_3749	1.877e-82	282.0	COG3267@1|root,COG3267@2|Bacteria,46SXM@74201|Verrucomicrobia,3K91Q@414999|Opitutae	414999|Opitutae	U	Pfam:Arch_ATPase	-	-	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22
CH3_k127_3166335_26	1183438.GKIL_2126	2.616e-37	149.0	COG1266@1|root,COG1266@2|Bacteria,1GFE4@1117|Cyanobacteria	1117|Cyanobacteria	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
CH3_k127_3166335_16	1254432.SCE1572_38850	7.474e-80	286.0	COG0564@1|root,COG1092@1|root,COG0564@2|Bacteria,COG1092@2|Bacteria,1PUHQ@1224|Proteobacteria,42Q87@68525|delta/epsilon subdivisions,2WPIN@28221|Deltaproteobacteria,2Z02J@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the methyltransferase superfamily	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,PseudoU_synth_2
CH3_k127_3166335_0	452637.Oter_1454	0.0	1373.0	COG0841@1|root,COG0841@2|Bacteria,46SER@74201|Verrucomicrobia	74201|Verrucomicrobia	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
CH3_k127_3166335_19	452637.Oter_1455	5.366e-62	228.0	COG0845@1|root,COG0845@2|Bacteria,46US2@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
CH3_k127_3166335_13	452637.Oter_1456	4.2e-83	295.0	COG1538@1|root,COG1538@2|Bacteria,46TY1@74201|Verrucomicrobia	74201|Verrucomicrobia	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
CH3_k127_3166335_32	1056820.KB900646_gene3544	5.229e-20	92.0	COG0607@1|root,32YCZ@2|Bacteria,1N6NN@1224|Proteobacteria,1SCRA@1236|Gammaproteobacteria,2PQGZ@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	P	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
CH3_k127_3166335_39	1168289.AJKI01000035_gene3570	5.528e-12	68.0	2AD45@1|root,312SH@2|Bacteria,4PHQV@976|Bacteroidetes,2G1PE@200643|Bacteroidia,3XKFZ@558415|Marinilabiliaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_3166335_33	926566.Terro_2606	4.368e-19	90.0	COG0640@1|root,COG0640@2|Bacteria,3Y5UV@57723|Acidobacteria,2JNP2@204432|Acidobacteriia	204432|Acidobacteriia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
CH3_k127_3167024_0	1125863.JAFN01000001_gene1137	1.49e-61	218.0	COG0518@1|root,COG0518@2|Bacteria,1MUDH@1224|Proteobacteria,42TJM@68525|delta/epsilon subdivisions,2WQGN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	PFAM Glutamine amidotransferase class-I	-	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
CH3_k127_3167024_2	497964.CfE428DRAFT_1105	6.564e-43	173.0	COG1427@1|root,COG1427@2|Bacteria,46VTU@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnA	-	4.2.1.151	ko:K11782	ko00130,ko01110,map00130,map01110	-	R10666	RC03232	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
CH3_k127_3167024_1	478741.JAFS01000001_gene1574	4.317e-55	203.0	COG1597@1|root,COG1597@2|Bacteria,46SR5@74201|Verrucomicrobia,37G0D@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	G	Diacylglycerol kinase catalytic domain (presumed)	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
CH3_k127_3167024_3	497964.CfE428DRAFT_3787	2.469e-06	60.0	COG4726@1|root,COG4726@2|Bacteria,46T3V@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	Pilus assembly protein PilX	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_3174478_5	330214.NIDE4374	5.684e-05	46.0	COG1091@1|root,COG1091@2|Bacteria	2|Bacteria	M	dTDP-4-dehydrorhamnose reductase activity	rmlD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
CH3_k127_3174478_0	278957.ABEA03000112_gene1387	2.947e-153	489.0	COG0388@1|root,COG0388@2|Bacteria,46S7B@74201|Verrucomicrobia,3K7B2@414999|Opitutae	414999|Opitutae	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
CH3_k127_3174478_1	452637.Oter_2651	7.425e-104	348.0	COG0515@1|root,COG0515@2|Bacteria,46U28@74201|Verrucomicrobia,3K7QD@414999|Opitutae	414999|Opitutae	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CH3_k127_3174478_4	330214.NIDE4047	2.482e-27	114.0	COG0776@1|root,COG0776@2|Bacteria	2|Bacteria	L	regulation of translation	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
CH3_k127_3174478_3	243231.GSU2683	9.588e-82	284.0	COG1893@1|root,COG1893@2|Bacteria,1RFSW@1224|Proteobacteria,43AIX@68525|delta/epsilon subdivisions,2X5Z6@28221|Deltaproteobacteria,43T9T@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	panE	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2643	ApbA,ApbA_C
CH3_k127_3174478_2	237368.SCABRO_01321	3.222e-82	283.0	COG0008@1|root,COG0008@2|Bacteria,2IXD6@203682|Planctomycetes	203682|Planctomycetes	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
CH3_k127_3175800_7	251221.35211558	1.871e-20	105.0	COG1404@1|root,COG2706@1|root,COG3391@1|root,COG1404@2|Bacteria,COG2706@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Calx-beta,DUF4347,HemolysinCabind,Peptidase_S8,TIG,VCBS
CH3_k127_3175800_6	1499967.BAYZ01000068_gene1988	5.261e-37	154.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CH3_k127_3175800_4	452637.Oter_4548	3.225e-48	174.0	COG1993@1|root,COG1993@2|Bacteria,46VZM@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Uncharacterized ACR, COG1993	-	-	-	ko:K09137	-	-	-	-	ko00000	-	-	-	DUF190
CH3_k127_3175800_3	452637.Oter_4547	1.932e-49	179.0	COG0239@1|root,COG0239@2|Bacteria,46W5U@74201|Verrucomicrobia,3K8J7@414999|Opitutae	414999|Opitutae	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
CH3_k127_3175800_9	159087.Daro_0466	3.186e-05	46.0	COG1555@1|root,COG1555@2|Bacteria,1N6Q3@1224|Proteobacteria,2VVT0@28216|Betaproteobacteria,2KXPG@206389|Rhodocyclales	206389|Rhodocyclales	L	Helix-hairpin-helix motif	-	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3
CH3_k127_3175800_8	1396141.BATP01000029_gene2250	9.194e-16	90.0	COG1525@1|root,COG1525@2|Bacteria,46WA1@74201|Verrucomicrobia,2IWGX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	nuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_3175800_1	1345023.M467_12970	6.95e-171	546.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,4HAKI@91061|Bacilli,3WDYC@539002|Bacillales incertae sedis	91061|Bacilli	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0044877,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
CH3_k127_3175800_0	497964.CfE428DRAFT_4750	4.515e-201	648.0	COG2204@1|root,COG4191@1|root,COG2204@2|Bacteria,COG4191@2|Bacteria,46TV0@74201|Verrucomicrobia	74201|Verrucomicrobia	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
CH3_k127_3175800_2	497964.CfE428DRAFT_4749	6.647e-104	369.0	COG4191@1|root,COG5000@1|root,COG4191@2|Bacteria,COG5000@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.1.1.80,2.7.13.3,3.1.1.61	ko:K13598,ko:K13924	ko02020,ko02030,map02020,map02030	M00498,M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	ABC_sub_bind,CHASE4,GAF,HAMP,HATPase_c,HDOD,HisKA,PAS,PAS_3,PAS_4,PAS_9
CH3_k127_3175800_5	1237149.C900_03088	5.835e-43	164.0	2E3CB@1|root,32YBM@2|Bacteria,4PPUF@976|Bacteroidetes	2|Bacteria	S	Domain of unknown function (DUF4154)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4154
CH3_k127_3182562_4	991.IW20_18470	3.155e-92	319.0	COG3119@1|root,COG3119@2|Bacteria,4NE7S@976|Bacteroidetes,1I2RA@117743|Flavobacteriia,2NVTT@237|Flavobacterium	976|Bacteroidetes	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	DUF4976,Sulfatase
CH3_k127_3182562_1	497964.CfE428DRAFT_6648	1.546e-176	568.0	COG3119@1|root,COG3119@2|Bacteria,46UMG@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4994,Sulfatase
CH3_k127_3182562_0	313603.FB2170_02110	2.938e-253	817.0	COG1621@1|root,COG3119@1|root,COG1621@2|Bacteria,COG3119@2|Bacteria,4NF1X@976|Bacteroidetes,1HYYH@117743|Flavobacteriia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CH3_k127_3182562_3	1396418.BATQ01000141_gene3317	3.182e-124	406.0	COG0657@1|root,COG1413@1|root,COG0657@2|Bacteria,COG1413@2|Bacteria,46TYV@74201|Verrucomicrobia	74201|Verrucomicrobia	CI	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,DUF1080
CH3_k127_3182562_2	861299.J421_0969	7.845e-169	542.0	COG3119@1|root,COG3119@2|Bacteria,1ZUXF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Domain of unknown function (DUF4976)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CH3_k127_3183747_4	1183438.GKIL_4354	1.751e-96	327.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
CH3_k127_3183747_0	251221.35211765	1.156e-191	629.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CH3_k127_3183747_1	1183438.GKIL_4354	4.754e-170	562.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
CH3_k127_3183747_3	452637.Oter_1900	5.193e-111	363.0	COG1136@1|root,COG1136@2|Bacteria,46TVQ@74201|Verrucomicrobia	74201|Verrucomicrobia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CH3_k127_3183747_2	1183438.GKIL_2517	4.323e-131	430.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
CH3_k127_3209744_6	1116472.MGMO_115c00240	2.288e-42	164.0	COG1305@1|root,COG1305@2|Bacteria	2|Bacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
CH3_k127_3209744_9	671143.DAMO_0355	4.57e-07	55.0	COG4096@1|root,COG4096@2|Bacteria	2|Bacteria	L	type I site-specific deoxyribonuclease activity	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	EcoEI_R_C,HSDR_N,HSDR_N_2,Helicase_C,ResIII
CH3_k127_3209744_0	272134.KB731324_gene3214	3.588e-251	797.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1G1Q1@1117|Cyanobacteria,1H8JB@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	DUF3471,PD40,Peptidase_S9,Peptidase_S9_N
CH3_k127_3209744_7	1123242.JH636434_gene5340	1.359e-37	162.0	COG1413@1|root,COG1413@2|Bacteria,2IZE1@203682|Planctomycetes	203682|Planctomycetes	C	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
CH3_k127_3209744_3	452637.Oter_3509	3.961e-89	310.0	COG0673@1|root,COG0673@2|Bacteria,46TMZ@74201|Verrucomicrobia,3K8Y2@414999|Opitutae	414999|Opitutae	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CH3_k127_3209744_1	595460.RRSWK_06183	3.984e-114	384.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CH3_k127_3209744_5	595460.RRSWK_06184	7.809e-48	184.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	NHL
CH3_k127_3209744_4	1168034.FH5T_01560	5.044e-69	240.0	2DVMZ@1|root,33WFQ@2|Bacteria,4P3VR@976|Bacteroidetes,2FXVM@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	-
CH3_k127_3209744_2	1168034.FH5T_01555	6.516e-109	369.0	COG0348@1|root,COG0348@2|Bacteria,4NPVD@976|Bacteroidetes,2FTEY@200643|Bacteroidia	976|Bacteroidetes	C	FMN-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_5
CH3_k127_3209744_8	1168034.FH5T_01550	2.07e-14	84.0	COG1520@1|root,COG1520@2|Bacteria,4P1VG@976|Bacteroidetes,2FW8D@200643|Bacteroidia	976|Bacteroidetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CH3_k127_3209947_12	682795.AciX8_0452	8.151e-47	171.0	COG2896@1|root,COG2896@2|Bacteria,3Y30D@57723|Acidobacteria,2JIKJ@204432|Acidobacteriia	204432|Acidobacteriia	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_14,Mob_synth_C,Radical_SAM
CH3_k127_3209947_18	497964.CfE428DRAFT_4379	1.275e-26	116.0	COG1664@1|root,COG1664@2|Bacteria,46VS6@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
CH3_k127_3209947_19	497964.CfE428DRAFT_4380	3.032e-25	113.0	COG1664@1|root,COG1664@2|Bacteria,46WDW@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
CH3_k127_3209947_15	497964.CfE428DRAFT_3022	2.959e-35	138.0	COG2363@1|root,COG2363@2|Bacteria,46T86@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF423)	-	-	-	-	-	-	-	-	-	-	-	-	DUF423
CH3_k127_3209947_24	497964.CfE428DRAFT_5963	5.293e-12	78.0	2F7AY@1|root,33ZS4@2|Bacteria,46VZW@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_3209947_22	1396141.BATP01000023_gene664	7.406e-17	94.0	COG2931@1|root,COG3266@1|root,COG4733@1|root,COG4932@1|root,COG2931@2|Bacteria,COG3266@2|Bacteria,COG4733@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K20541	-	-	-	-	ko00000,ko02000	4.D.3.1.6	-	-	BcsB,DUF1499,Flg_new
CH3_k127_3209947_3	452637.Oter_4549	2.639e-110	366.0	28JIN@1|root,30U02@2|Bacteria,46YTT@74201|Verrucomicrobia,3K7XH@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_3209947_5	382464.ABSI01000013_gene1636	1.872e-92	312.0	COG0123@1|root,COG0123@2|Bacteria,46SMT@74201|Verrucomicrobia,2IUMK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
CH3_k127_3209947_14	525904.Tter_2300	4.556e-36	142.0	COG4276@1|root,COG4276@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	Polyketide_cyc
CH3_k127_3209947_25	316274.Haur_4856	1.564e-11	79.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	quiC	-	4.2.1.118	ko:K09483	ko00400,ko01110,ko01130,map00400,map01110,map01130	-	R01627	RC00568	ko00000,ko00001,ko01000	-	-	-	Beta_helix,CHU_C,NosD
CH3_k127_3209947_23	661478.OP10G_4013	3.176e-15	86.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456,ko:K02650	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,T2SSG
CH3_k127_3209947_9	880070.Cycma_0098	4.063e-65	240.0	COG1387@1|root,COG1387@2|Bacteria	2|Bacteria	E	zinc ion binding	-	-	3.1.3.15	ko:K02347,ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	PHP
CH3_k127_3209947_6	616991.JPOO01000003_gene1324	4.712e-89	311.0	COG3356@1|root,COG3356@2|Bacteria,4NGDG@976|Bacteroidetes,1I821@117743|Flavobacteriia,23FKJ@178469|Arenibacter	976|Bacteroidetes	S	Neutral/alkaline non-lysosomal ceramidase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
CH3_k127_3209947_10	1459636.NTE_02269	4.69e-50	184.0	COG0431@1|root,arCOG04624@2157|Archaea	2157|Archaea	S	NAD(P)H-dependent FMN reductase	ssuE1	-	1.5.1.38	ko:K00299	ko00740,ko00920,ko01100,map00740,map00920,map01100	-	R05706,R07210,R10206	RC00126,RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	FMN_red
CH3_k127_3209947_8	497964.CfE428DRAFT_4164	1.474e-66	237.0	COG0483@1|root,COG0483@2|Bacteria,46T0Z@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Inositol monophosphatase family	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
CH3_k127_3209947_16	493475.GARC_3222	6.252e-31	135.0	COG0652@1|root,COG0652@2|Bacteria,1RCXX@1224|Proteobacteria,1S3ZN@1236|Gammaproteobacteria,466T7@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03767	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
CH3_k127_3209947_11	1121422.AUMW01000010_gene1055	9.15e-48	180.0	COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,249GK@186801|Clostridia,261IR@186807|Peptococcaceae	186801|Clostridia	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
CH3_k127_3209947_21	1189620.AJXL01000002_gene1866	6.668e-19	95.0	COG2032@1|root,COG2032@2|Bacteria,4NGGW@976|Bacteroidetes,1HY8P@117743|Flavobacteriia,2NYDV@237|Flavobacterium	976|Bacteroidetes	P	superoxide dismutase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
CH3_k127_3209947_27	1089545.KB913037_gene8972	1.017e-06	58.0	COG3794@1|root,COG3794@2|Bacteria,2H73G@201174|Actinobacteria,4E2Z7@85010|Pseudonocardiales	201174|Actinobacteria	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
CH3_k127_3209947_17	497964.CfE428DRAFT_3521	7.476e-28	132.0	COG2010@1|root,COG2010@2|Bacteria,46TD5@74201|Verrucomicrobia	2|Bacteria	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,PSCyt1,PSCyt2,PSD1
CH3_k127_3209947_7	452637.Oter_2583	7.462e-83	283.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	omcI	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
CH3_k127_3209947_13	452637.Oter_0299	1.663e-45	170.0	COG1595@1|root,COG1595@2|Bacteria,46VX9@74201|Verrucomicrobia	74201|Verrucomicrobia	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CH3_k127_3209947_20	452637.Oter_0300	1.124e-22	108.0	COG5662@1|root,COG5662@2|Bacteria	2|Bacteria	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	DUF3379
CH3_k127_3209947_26	278957.ABEA03000106_gene1817	9.457e-07	60.0	COG4968@1|root,COG4968@2|Bacteria,46Y7B@74201|Verrucomicrobia,3K91Z@414999|Opitutae	414999|Opitutae	NU	Prepilin-type N-terminal cleavage methylation domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_3209947_0	497964.CfE428DRAFT_5324	0.0	1110.0	COG0495@1|root,COG0495@2|Bacteria,46SF4@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
CH3_k127_3209947_4	497964.CfE428DRAFT_2087	7.675e-103	345.0	COG0500@1|root,COG0640@1|root,COG0640@2|Bacteria,COG2226@2|Bacteria,46SDC@74201|Verrucomicrobia	74201|Verrucomicrobia	KQ	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5,Methyltransf_11,Methyltransf_31
CH3_k127_3209947_1	497964.CfE428DRAFT_2088	1.208e-195	615.0	COG0192@1|root,COG0192@2|Bacteria,46S4V@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
CH3_k127_3209947_2	1121015.N789_09735	1.463e-166	528.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,1RMW8@1236|Gammaproteobacteria,1X33V@135614|Xanthomonadales	135614|Xanthomonadales	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
CH3_k127_3238477_2	575540.Isop_1592	2.092e-62	220.0	COG0209@1|root,COG0209@2|Bacteria,2IX3H@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
CH3_k127_3238477_1	562970.Btus_1769	2.806e-108	368.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,4HAJ6@91061|Bacilli,278SV@186823|Alicyclobacillaceae	91061|Bacilli	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
CH3_k127_3238477_0	497964.CfE428DRAFT_2485	1.136e-185	588.0	COG1904@1|root,COG1904@2|Bacteria	2|Bacteria	G	glucuronate isomerase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_3238477_4	497964.CfE428DRAFT_2603	1.027e-24	113.0	COG4700@1|root,COG4700@2|Bacteria	2|Bacteria	T	PFAM Protein kinase domain	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	GerE,PLDc_N,TPR_16,TPR_19,TPR_4,TPR_6,TPR_8
CH3_k127_3238477_3	883067.HMPREF9237_01193	9.033e-28	128.0	COG1216@1|root,COG1216@2|Bacteria,2I2FA@201174|Actinobacteria,4D48A@85005|Actinomycetales	201174|Actinobacteria	S	Glycosyltransferase, group 2 family protein	ppm1	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
CH3_k127_3250050_2	1121346.KB899838_gene1222	3.346e-71	244.0	COG0329@1|root,COG0329@2|Bacteria,1UNIU@1239|Firmicutes,4HAWE@91061|Bacilli,26TG8@186822|Paenibacillaceae	91061|Bacilli	EM	dihydrodipicolinate synthetase	-	-	-	-	-	-	-	-	-	-	-	-	DHDPS
CH3_k127_3250050_0	314230.DSM3645_20627	3.248e-142	466.0	COG1520@1|root,COG1520@2|Bacteria,2IWR8@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CH3_k127_3250050_1	497964.CfE428DRAFT_0022	2.125e-80	274.0	COG0217@1|root,COG0217@2|Bacteria,46SMV@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
CH3_k127_3250050_3	240016.ABIZ01000001_gene4136	5.438e-26	111.0	COG2010@1|root,COG3241@1|root,COG2010@2|Bacteria,COG3241@2|Bacteria	2|Bacteria	C	Transfers electrons from cytochrome c551 to cytochrome oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cytochrom_C,F5_F8_type_C,HEAT_2,Lipase_GDSL_2
CH3_k127_3252798_1	1122135.KB893134_gene3934	9.883e-56	203.0	COG1011@1|root,COG1011@2|Bacteria	2|Bacteria	S	phosphatase activity	-	-	3.1.3.10	ko:K07025,ko:K20866	ko00010,ko01120,map00010,map01120	-	R00947	RC00078	ko00000,ko00001,ko01000	-	-	-	HAD_2,Hydrolase,Hydrolase_like
CH3_k127_3252798_0	234267.Acid_2266	8.769e-219	704.0	COG2319@1|root,COG2319@2|Bacteria	2|Bacteria	S	anaphase-promoting complex binding	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,WD40
CH3_k127_3252798_2	234267.Acid_2265	3.232e-51	183.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CH3_k127_3258956_5	1283287.KB822578_gene2242	3.994e-21	100.0	COG1215@1|root,COG1215@2|Bacteria,2GJTE@201174|Actinobacteria,4DNZE@85009|Propionibacteriales	201174|Actinobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,GtrA
CH3_k127_3258956_0	1123242.JH636436_gene130	7.869e-165	537.0	COG2804@1|root,COG2804@2|Bacteria,2IYEE@203682|Planctomycetes	203682|Planctomycetes	NU	COG2804 Type II secretory pathway ATPase PulE Tfp pilus assembly pathway ATPase PilB	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
CH3_k127_3258956_1	1123508.JH636439_gene1318	2.683e-64	237.0	COG1459@1|root,COG1459@2|Bacteria,2IXYZ@203682|Planctomycetes	203682|Planctomycetes	U	Type 4 fimbrial assembly protein pilC	-	-	-	ko:K02455,ko:K02653	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
CH3_k127_3258956_2	1125863.JAFN01000001_gene2967	1.562e-36	143.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,42SFB@68525|delta/epsilon subdivisions,2WP3B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	general secretion pathway protein G	gspG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
CH3_k127_3258956_9	745411.B3C1_05932	0.0002703	51.0	COG4970@1|root,COG4970@2|Bacteria,1NBWI@1224|Proteobacteria,1S5MN@1236|Gammaproteobacteria,1J9VA@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	NU	general secretion pathway protein	xpsH	-	-	ko:K02457	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	GspH,N_methyl
CH3_k127_3258956_8	1479238.JQMZ01000001_gene267	6.582e-05	50.0	COG2165@1|root,COG2165@2|Bacteria,1NH8A@1224|Proteobacteria,2UK2Q@28211|Alphaproteobacteria,43YW6@69657|Hyphomonadaceae	28211|Alphaproteobacteria	NU	General secretion pathway protein I	-	-	-	ko:K02458	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSI
CH3_k127_3258956_6	1123508.JH636450_gene7091	6.833e-07	60.0	COG4795@1|root,COG4795@2|Bacteria,2J03I@203682|Planctomycetes	203682|Planctomycetes	U	General secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
CH3_k127_3258956_3	1123242.JH636435_gene2166	2.985e-32	143.0	COG3156@1|root,COG3156@2|Bacteria,2IXHV@203682|Planctomycetes	203682|Planctomycetes	U	Type II secretion system (T2SS), protein K	-	-	-	-	-	-	-	-	-	-	-	-	T2SSK
CH3_k127_3258956_7	1540221.JQNI01000002_gene1751	8.43e-06	58.0	COG4972@1|root,COG4972@2|Bacteria,1WJKT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	NU	TIGRFAM type IV pilus assembly protein PilM	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
CH3_k127_3258956_4	1121921.KB898712_gene2233	2.395e-23	115.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,1RPJS@1236|Gammaproteobacteria,2PN33@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	NU	Bacterial type II and III secretion system protein	gspD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
CH3_k127_3262745_1	1304885.AUEY01000096_gene2839	1.013e-195	631.0	COG1404@1|root,COG2304@1|root,COG2911@1|root,COG3897@1|root,COG5434@1|root,COG1404@2|Bacteria,COG2304@2|Bacteria,COG2911@2|Bacteria,COG3897@2|Bacteria,COG5434@2|Bacteria,1P8N9@1224|Proteobacteria,43DXZ@68525|delta/epsilon subdivisions,2X72D@28221|Deltaproteobacteria,2MNHJ@213118|Desulfobacterales	28221|Deltaproteobacteria	E	alginic acid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
CH3_k127_3262745_2	1313421.JHBV01000041_gene3629	5.337e-186	609.0	COG2304@1|root,COG2304@2|Bacteria,4NK2W@976|Bacteroidetes	976|Bacteroidetes	M	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	OmpA,VIT,VWA,VWA_3
CH3_k127_3262745_5	42565.FP66_10530	4.905e-07	61.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,1RPI3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	COG0790 FOG TPR repeat, SEL1 subfamily	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	SPOR,Sel1
CH3_k127_3262745_6	46234.ANA_C10684	5.947e-06	51.0	COG2026@1|root,COG2026@2|Bacteria,1GA93@1117|Cyanobacteria,1HT80@1161|Nostocales	1117|Cyanobacteria	DJ	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
CH3_k127_3262745_4	1121904.ARBP01000002_gene7118	2.604e-11	78.0	COG3250@1|root,COG3250@2|Bacteria,4NN59@976|Bacteroidetes	976|Bacteroidetes	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BetaGal_dom4_5
CH3_k127_3262745_3	383372.Rcas_3244	2.083e-70	271.0	COG3250@1|root,COG3250@2|Bacteria,2G6ZW@200795|Chloroflexi	200795|Chloroflexi	G	glycoside hydrolase family 2 sugar binding	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2_C,Glyco_hydro_2_N
CH3_k127_3262745_0	314230.DSM3645_10902	7.288e-276	872.0	COG0823@1|root,COG1506@1|root,COG4805@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,COG4805@2|Bacteria,2IY8M@203682|Planctomycetes	203682|Planctomycetes	E	Dipeptidyl peptidase IV (DPP IV)	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,DUF885,Peptidase_S9,VHL
CH3_k127_3264124_1	497964.CfE428DRAFT_0118	1.055e-95	324.0	COG1972@1|root,COG1972@2|Bacteria,46S7I@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Na dependent nucleoside transporter domain protein	-	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
CH3_k127_3264124_2	1123368.AUIS01000006_gene589	4.04e-32	135.0	2AKF7@1|root,31B6Q@2|Bacteria,1N34J@1224|Proteobacteria,1SHID@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_3264124_3	1118058.CAGY01000002_gene772	5.448e-08	68.0	COG2373@1|root,COG4932@1|root,COG2373@2|Bacteria,COG4932@2|Bacteria,2I66Z@201174|Actinobacteria,4D38B@85005|Actinomycetales	201174|Actinobacteria	M	SdrD B-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,SdrD_B
CH3_k127_3264124_0	864051.BurJ1DRAFT_3700	4.348e-134	484.0	COG0726@1|root,COG0823@1|root,COG2911@1|root,COG2931@1|root,COG3210@1|root,COG3420@1|root,COG0726@2|Bacteria,COG0823@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3420@2|Bacteria,1MU7T@1224|Proteobacteria,2WI67@28216|Betaproteobacteria,1KMDS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	MQU	Domain of unknown function (DUF4347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347
CH3_k127_3282107_25	530564.Psta_0956	3.709e-17	85.0	COG0584@1|root,COG0584@2|Bacteria,2IZ1A@203682|Planctomycetes	203682|Planctomycetes	C	glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
CH3_k127_3282107_2	452637.Oter_2454	1.319e-250	784.0	COG0659@1|root,COG0659@2|Bacteria,46THR@74201|Verrucomicrobia,3K7K8@414999|Opitutae	414999|Opitutae	P	Sulfate transporter antisigma-factor antagonist STAS	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
CH3_k127_3282107_29	452637.Oter_1279	2.266e-12	74.0	COG1579@1|root,COG1579@2|Bacteria	2|Bacteria	-	-	oppA	-	2.1.1.80,3.1.1.61	ko:K13582,ko:K13924,ko:K15580	ko01501,ko02010,ko02020,ko02024,ko02030,ko04112,map01501,map02010,map02020,map02024,map02030,map04112	M00439,M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02000,ko02022,ko02035	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	CheB_methylest,CheR,CheR_N,DUF285,Flg_new,HWE_HK,PAS_10,SBP_bac_5
CH3_k127_3282107_16	497964.CfE428DRAFT_5455	7.301e-72	248.0	COG2344@1|root,COG2344@2|Bacteria	2|Bacteria	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
CH3_k127_3282107_23	497964.CfE428DRAFT_6314	9.15e-27	113.0	2E63P@1|root,330SQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_3282107_17	481448.Minf_1859	2.564e-70	258.0	COG0763@1|root,COG0763@2|Bacteria,46SSG@74201|Verrucomicrobia,37GGI@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
CH3_k127_3282107_9	497964.CfE428DRAFT_0881	1.925e-107	359.0	COG0673@1|root,COG0673@2|Bacteria,46SAE@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, NAD-binding Rossmann fold	mviM	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CH3_k127_3282107_20	1123070.KB899247_gene1454	1.426e-43	167.0	COG0344@1|root,COG0344@2|Bacteria,46VTA@74201|Verrucomicrobia,2IUDC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Glycerol-3-phosphate acyltransferase	-	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
CH3_k127_3282107_14	243231.GSU0006	1.599e-82	291.0	COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,42NQB@68525|delta/epsilon subdivisions,2WIWW@28221|Deltaproteobacteria,43TUN@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	NAD-dependent glycerol-3-phosphate dehydrogenase domain protein	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
CH3_k127_3282107_0	1396141.BATP01000016_gene2780	0.0	1552.0	COG1075@1|root,COG4099@1|root,COG4625@1|root,COG1075@2|Bacteria,COG4099@2|Bacteria,COG4625@2|Bacteria	2|Bacteria	T	pathogenesis	-	-	3.5.4.40	ko:K18286,ko:K20276	ko00130,ko01110,ko02024,map00130,map01110,map02024	-	R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_8,Big_5,SLH,SWM_repeat
CH3_k127_3282107_26	1385935.N836_13145	4.262e-15	92.0	COG1404@1|root,COG4447@1|root,COG1404@2|Bacteria,COG4447@2|Bacteria,1G72X@1117|Cyanobacteria	1117|Cyanobacteria	O	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_3282107_15	278957.ABEA03000104_gene310	3.228e-81	275.0	COG0560@1|root,COG0560@2|Bacteria,46X2A@74201|Verrucomicrobia,3K7WQ@414999|Opitutae	414999|Opitutae	E	TIGRFAM phosphoserine phosphatase homoserine phosphotransferase bifunctional protein	-	-	2.7.1.39,3.1.3.3	ko:K02203	ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00680,map01100,map01110,map01120,map01130,map01230	M00018	R00582,R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Hydrolase
CH3_k127_3282107_18	452637.Oter_3648	7.62e-50	190.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	ko:K12263	-	-	-	-	ko00000	-	-	-	Cytochrome_CBB3,SirB
CH3_k127_3282107_5	471854.Dfer_1899	6.89e-154	496.0	COG4409@1|root,COG4409@2|Bacteria,4NKEW@976|Bacteroidetes,47U77@768503|Cytophagia	976|Bacteroidetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
CH3_k127_3282107_27	247490.KSU1_D0417	2.151e-13	71.0	COG1052@1|root,COG1052@2|Bacteria,2IWTC@203682|Planctomycetes	203682|Planctomycetes	CH	PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	-	-	1.1.1.26	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	-	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
CH3_k127_3282107_7	641524.ADICYQ_2925	3.302e-143	462.0	COG0673@1|root,COG0673@2|Bacteria,4NFY3@976|Bacteroidetes,47ME7@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CH3_k127_3282107_19	234267.Acid_3103	6.766e-45	166.0	COG4948@1|root,COG4948@2|Bacteria,3Y46A@57723|Acidobacteria	57723|Acidobacteria	M	PFAM Mandelate racemase muconate lactonizing enzyme, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C
CH3_k127_3282107_28	278957.ABEA03000074_gene2977	2.289e-13	81.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CH3_k127_3282107_4	886293.Sinac_6825	1.837e-157	507.0	COG3356@1|root,COG3356@2|Bacteria,2IXX5@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Neutral alkaline nonlysosomal ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
CH3_k127_3282107_31	324602.Caur_0300	1.735e-11	71.0	290K2@1|root,2ZN8K@2|Bacteria,2G9HM@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_3282107_24	324602.Caur_0299	3.86e-18	99.0	COG5295@1|root,COG5295@2|Bacteria,2GB82@200795|Chloroflexi,377IZ@32061|Chloroflexia	32061|Chloroflexia	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectinesterase
CH3_k127_3282107_32	324602.Caur_0300	4.492e-11	69.0	290K2@1|root,2ZN8K@2|Bacteria,2G9HM@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_3282107_30	251221.35210810	2.29e-12	68.0	COG5295@1|root,COG5295@2|Bacteria,1GB93@1117|Cyanobacteria	1117|Cyanobacteria	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_3282107_13	1123248.KB893329_gene4465	2.965e-93	317.0	COG0524@1|root,COG0524@2|Bacteria,4NENQ@976|Bacteroidetes,1IUX3@117747|Sphingobacteriia	976|Bacteroidetes	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
CH3_k127_3282107_12	1123487.KB892834_gene3009	1.344e-98	331.0	COG1172@1|root,COG1172@2|Bacteria,1MX7D@1224|Proteobacteria,2WH7G@28216|Betaproteobacteria,2KZQT@206389|Rhodocyclales	28216|Betaproteobacteria	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
CH3_k127_3282107_10	543728.Vapar_4636	9.723e-107	355.0	COG1879@1|root,COG1879@2|Bacteria,1NRXG@1224|Proteobacteria,2VM9V@28216|Betaproteobacteria,4ADDA@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM Periplasmic binding protein LacI transcriptional regulator	rbsB2	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
CH3_k127_3282107_6	344747.PM8797T_25701	1.072e-153	496.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,VCBS
CH3_k127_3282107_22	1267535.KB906767_gene4834	8.445e-34	146.0	COG1874@1|root,COG1874@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4832,Glyco_hydro_14,Glyco_hydro_42,Glyco_hydro_42M
CH3_k127_3282107_8	344747.PM8797T_24141	7.661e-130	426.0	COG1520@1|root,COG1520@2|Bacteria,2IYK2@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
CH3_k127_3282107_11	240016.ABIZ01000001_gene2238	9.771e-102	344.0	COG1250@1|root,COG1250@2|Bacteria,46TNQ@74201|Verrucomicrobia,2IWBJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	3-hydroxyacyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_3282107_3	1123508.JH636448_gene7659	1.193e-199	629.0	COG2730@1|root,COG2730@2|Bacteria,2IZBB@203682|Planctomycetes	203682|Planctomycetes	G	Protein of unknown function (DUF4038)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF4038,DUF5060
CH3_k127_3282107_1	452637.Oter_3479	0.0	1029.0	COG0129@1|root,COG0129@2|Bacteria,46UGZ@74201|Verrucomicrobia,3K7Q8@414999|Opitutae	414999|Opitutae	EG	Belongs to the IlvD Edd family	-	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
CH3_k127_3293125_0	251221.35214444	9.805e-217	695.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	dpp4	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,PD40,Peptidase_S9
CH3_k127_3293125_4	497964.CfE428DRAFT_0725	5.004e-36	149.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
CH3_k127_3293125_1	1122605.KB893625_gene1683	9.523e-206	658.0	COG1501@1|root,COG1501@2|Bacteria,4PKHN@976|Bacteroidetes,1IP35@117747|Sphingobacteriia	976|Bacteroidetes	G	He_PIG associated, NEW1 domain of bacterial glycohydrolase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	He_PIG,He_PIG_assoc,Melibiase_2,NPCBM
CH3_k127_3293125_5	935839.JAGJ01000024_gene2469	5.605e-26	124.0	COG0737@1|root,COG3250@1|root,COG3934@1|root,COG4409@1|root,COG0737@2|Bacteria,COG3250@2|Bacteria,COG3934@2|Bacteria,COG4409@2|Bacteria,2I0CJ@201174|Actinobacteria	201174|Actinobacteria	G	BNR Asp-box repeat	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,DUF4091,F5_F8_type_C,NPCBM,NPCBM_assoc
CH3_k127_3293125_3	1122915.AUGY01000073_gene4393	5.649e-39	164.0	COG4030@1|root,COG4030@2|Bacteria,1TRZY@1239|Firmicutes,4IT8Q@91061|Bacilli,277AM@186822|Paenibacillaceae	91061|Bacilli	S	Protein of unknown function (DUF2961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
CH3_k127_3293125_6	1303518.CCALI_02493	9.535e-09	66.0	COG4969@1|root,COG4969@2|Bacteria	2|Bacteria	NU	cell adhesion	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,SBP_bac_10
CH3_k127_3293125_2	1089553.Tph_c09100	4.801e-98	338.0	COG0407@1|root,COG0407@2|Bacteria,1TRJG@1239|Firmicutes,24B34@186801|Clostridia,42G9W@68295|Thermoanaerobacterales	186801|Clostridia	H	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
CH3_k127_3293125_7	1089553.Tph_c09110	0.0002461	53.0	2CJTW@1|root,33NBH@2|Bacteria,1VM99@1239|Firmicutes,24UVS@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_3295104_2	234267.Acid_1336	3.154e-14	72.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,TAT_signal
CH3_k127_3295104_0	1403819.BATR01000069_gene2027	6.478e-159	509.0	COG2382@1|root,COG3693@1|root,COG2382@2|Bacteria,COG3693@2|Bacteria,46YZE@74201|Verrucomicrobia,2IU0Q@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
CH3_k127_3295104_1	240016.ABIZ01000001_gene4315	9.338e-59	218.0	COG1167@1|root,COG1167@2|Bacteria,46STK@74201|Verrucomicrobia,2IVDB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EK	Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
CH3_k127_3296438_2	1396141.BATP01000042_gene1908	1.443e-39	147.0	COG1765@1|root,COG1765@2|Bacteria	2|Bacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
CH3_k127_3296438_1	1396418.BATQ01000092_gene5859	3.807e-104	349.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
CH3_k127_3296438_3	1385518.N798_14125	1.37e-34	137.0	COG3427@1|root,COG3427@2|Bacteria,2ISBF@201174|Actinobacteria,4FH30@85021|Intrasporangiaceae	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
CH3_k127_3296438_0	314230.DSM3645_26339	1.177e-193	614.0	COG2755@1|root,COG2755@2|Bacteria,2IYT9@203682|Planctomycetes	203682|Planctomycetes	E	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,Lipase_GDSL_2
CH3_k127_3296438_5	469383.Cwoe_4336	6.301e-09	65.0	2B4AG@1|root,31X1X@2|Bacteria,2GWKS@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_3296438_4	1121335.Clst_0783	5.492e-30	119.0	COG0524@1|root,COG0524@2|Bacteria,1TRRY@1239|Firmicutes,248Y3@186801|Clostridia,3WHKM@541000|Ruminococcaceae	186801|Clostridia	G	Kinase, PfkB family	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
CH3_k127_3332350_10	1396418.BATQ01000001_gene1289	1.446e-06	53.0	COG1321@1|root,COG1321@2|Bacteria,46VZN@74201|Verrucomicrobia,2IUJN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Helix-turn-helix diphteria tox regulatory element	-	-	-	-	-	-	-	-	-	-	-	-	Fe_dep_repr_C,Fe_dep_repress
CH3_k127_3332350_5	518766.Rmar_1172	4.137e-51	193.0	COG1999@1|root,COG5569@1|root,COG1999@2|Bacteria,COG5569@2|Bacteria,4PEVF@976|Bacteroidetes,1FJP6@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	SCO1/SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	CusF_Ec,SCO1-SenC
CH3_k127_3332350_4	497964.CfE428DRAFT_0064	1.743e-56	205.0	COG1595@1|root,COG1595@2|Bacteria,46VJP@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
CH3_k127_3332350_3	1229205.BUPH_01539	7.294e-71	259.0	COG4409@1|root,COG4409@2|Bacteria,1Q513@1224|Proteobacteria,2WB3C@28216|Betaproteobacteria,1K536@119060|Burkholderiaceae	28216|Betaproteobacteria	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR,BNR_2
CH3_k127_3332350_1	1097668.BYI23_C006580	5.168e-95	329.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	msrB	-	1.8.4.11,1.8.4.12	ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA,PMSR,Redoxin,SelR,Thioredoxin
CH3_k127_3332350_7	102125.Xen7305DRAFT_00020060	8.615e-20	104.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CW_binding_1,VCBS
CH3_k127_3332350_9	1038862.KB893833_gene4667	1.227e-11	78.0	COG2931@1|root,COG3210@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,1MU7T@1224|Proteobacteria,2TTVN@28211|Alphaproteobacteria,3JXXS@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_3332350_8	313628.LNTAR_12286	2.362e-12	77.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CH3_k127_3332350_6	234267.Acid_3225	1.013e-27	130.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19,TPR_8,Trans_reg_C
CH3_k127_3332350_2	497964.CfE428DRAFT_0066	1.343e-82	300.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,46TTW@74201|Verrucomicrobia	74201|Verrucomicrobia	KLT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PEGA,Pkinase
CH3_k127_3332350_0	497964.CfE428DRAFT_4984	2.886e-201	642.0	COG1198@1|root,COG1198@2|Bacteria,46U3N@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
CH3_k127_3366859_11	522306.CAP2UW1_3973	2.814e-13	71.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,2VHUC@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
CH3_k127_3366859_4	1296990.H845_3380	9.821e-100	341.0	COG0517@1|root,COG0517@2|Bacteria,1MXI6@1224|Proteobacteria,2TS6X@28211|Alphaproteobacteria,2JU31@204441|Rhodospirillales	204441|Rhodospirillales	S	Transposase zinc-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
CH3_k127_3366859_7	945713.IALB_0431	5.572e-58	213.0	COG1102@1|root,COG1102@2|Bacteria	2|Bacteria	F	Psort location Cytoplasmic, score	-	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin2
CH3_k127_3366859_3	278957.ABEA03000027_gene1659	2.361e-101	344.0	COG1376@1|root,COG3409@1|root,COG1376@2|Bacteria,COG3409@2|Bacteria,46UGX@74201|Verrucomicrobia,3K7XD@414999|Opitutae	414999|Opitutae	M	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,YkuD
CH3_k127_3366859_1	1396418.BATQ01000136_gene3697	3.274e-288	897.0	COG0665@1|root,COG0665@2|Bacteria,46TKJ@74201|Verrucomicrobia,2IWQZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
CH3_k127_3366859_8	595460.RRSWK_04460	7.081e-26	108.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
CH3_k127_3366859_9	330214.NIDE2936	5.49e-19	89.0	COG1598@1|root,COG1598@2|Bacteria,3J1EZ@40117|Nitrospirae	40117|Nitrospirae	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_3366859_10	589924.Ferp_2052	8.694e-19	91.0	arCOG03086@1|root,arCOG03086@2157|Archaea,2Y7EV@28890|Euryarchaeota,247AD@183980|Archaeoglobi	183980|Archaeoglobi	S	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
CH3_k127_3366859_6	309799.DICTH_0179	6.057e-64	237.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	ko:K20952	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Beta-prism_lec,PQQ_2,PQQ_3,Pkinase,VCBS
CH3_k127_3366859_5	383372.Rcas_1067	1.363e-72	253.0	COG0259@1|root,COG0259@2|Bacteria,2G8DA@200795|Chloroflexi,376ZA@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	-	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
CH3_k127_3366859_0	497964.CfE428DRAFT_4373	0.0	1112.0	COG0188@1|root,COG0188@2|Bacteria,46SBE@74201|Verrucomicrobia	74201|Verrucomicrobia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
CH3_k127_3366859_2	240016.ABIZ01000001_gene3864	6.784e-126	412.0	COG0187@1|root,COG0187@2|Bacteria,46SDH@74201|Verrucomicrobia,2IU0E@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
CH3_k127_3373599_0	861299.J421_1753	1.227e-272	884.0	COG0446@1|root,COG4888@1|root,COG0446@2|Bacteria,COG4888@2|Bacteria	2|Bacteria	G	ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,Pyr_redox_2,UnbV_ASPIC,VCBS
CH3_k127_3373599_1	1089548.KI783301_gene681	7.707e-79	271.0	COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,4H9N5@91061|Bacilli,3WDY5@539002|Bacillales incertae sedis	91061|Bacilli	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
CH3_k127_3402550_6	485917.Phep_1459	2.396e-37	149.0	COG4225@1|root,COG4225@2|Bacteria,4NF1N@976|Bacteroidetes,1IP96@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Heparinase II III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4962,Hepar_II_III
CH3_k127_3402550_11	203119.Cthe_3006	0.0001447	52.0	COG1376@1|root,COG1388@1|root,COG1376@2|Bacteria,COG1388@2|Bacteria,1V9XU@1239|Firmicutes,24NW6@186801|Clostridia	186801|Clostridia	M	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,YkuD
CH3_k127_3402550_5	945713.IALB_3143	1.385e-60	214.0	COG0229@1|root,COG0229@2|Bacteria	2|Bacteria	O	peptide-methionine (R)-S-oxide reductase activity	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
CH3_k127_3402550_9	756272.Plabr_3911	3.415e-21	106.0	COG4632@1|root,COG4632@2|Bacteria,2J149@203682|Planctomycetes	203682|Planctomycetes	G	Phosphodiester glycosidase	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA
CH3_k127_3402550_7	671143.DAMO_0425	1.378e-28	117.0	COG3646@1|root,COG3646@2|Bacteria	2|Bacteria	L	Phage regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N
CH3_k127_3402550_8	936574.HMPREF1508_0899	1.276e-21	97.0	COG1502@1|root,COG1502@2|Bacteria,1TRJE@1239|Firmicutes,248ZE@186801|Clostridia	186801|Clostridia	I	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N
CH3_k127_3402550_0	1396418.BATQ01000166_gene1868	1.66e-215	675.0	COG0137@1|root,COG0137@2|Bacteria,46SCU@74201|Verrucomicrobia,2ITYG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Arginosuccinate synthase	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
CH3_k127_3402550_3	1379698.RBG1_1C00001G0123	3.721e-90	306.0	COG0053@1|root,COG0053@2|Bacteria,2NPHA@2323|unclassified Bacteria	2|Bacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	fieF	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
CH3_k127_3402550_2	880073.Calab_3201	5.68e-142	461.0	COG4198@1|root,COG4198@2|Bacteria,2NNV0@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function (DUF1015)	gdh	-	1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	-	R00248	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	DUF1015
CH3_k127_3402550_4	765420.OSCT_3130	2.482e-71	252.0	COG4932@1|root,COG5184@1|root,COG4932@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	ychO	GO:0005575,GO:0005623,GO:0008150,GO:0009279,GO:0009405,GO:0016020,GO:0019867,GO:0030260,GO:0030312,GO:0030313,GO:0031975,GO:0044403,GO:0044409,GO:0044419,GO:0044462,GO:0044464,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0071944	3.2.1.14	ko:K01183,ko:K20276	ko00520,ko01100,ko02024,map00520,map01100,map02024	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	He_PIG,IAT_beta,RCC1_2
CH3_k127_3402550_10	452637.Oter_3785	1.694e-19	90.0	COG0227@1|root,COG0227@2|Bacteria,46TBF@74201|Verrucomicrobia,3K89C@414999|Opitutae	414999|Opitutae	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
CH3_k127_3402550_1	794903.OPIT5_26225	1.043e-195	626.0	COG2804@1|root,COG2804@2|Bacteria,46XZ0@74201|Verrucomicrobia,3K8NA@414999|Opitutae	414999|Opitutae	NU	Type II secretion system (T2SS), protein E, N-terminal domain	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
CH3_k127_3409752_3	243233.MCA2830	7.601e-24	104.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,1RY8P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	amino acid	frlA	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006040,GO:0006082,GO:0006520,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008152,GO:0008509,GO:0008514,GO:0009056,GO:0009063,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0016054,GO:0019752,GO:0022804,GO:0022857,GO:0030389,GO:0030392,GO:0030393,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044425,GO:0044459,GO:0044464,GO:0046348,GO:0046395,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098656,GO:1901135,GO:1901136,GO:1901281,GO:1901564,GO:1901565,GO:1901575,GO:1902475,GO:1903825,GO:1905039	-	ko:K03294,ko:K19540	-	-	-	-	ko00000,ko02000	2.A.3.2,2.A.3.8.17	-	iAF1260.b3370,iB21_1397.B21_03173,iBWG_1329.BWG_3062,iEC042_1314.EC042_3632,iEC55989_1330.EC55989_3776,iECBD_1354.ECBD_0378,iECB_1328.ECB_03221,iECDH10B_1368.ECDH10B_3546,iECDH1ME8569_1439.ECDH1ME8569_3250,iECD_1391.ECD_03221,iECIAI1_1343.ECIAI1_3509,iECO111_1330.ECO111_4180,iECO26_1355.ECO26_4459,iETEC_1333.ETEC_3621,iEcDH1_1363.EcDH1_0342,iJO1366.b3370,iSSON_1240.SSON_3502,iUMNK88_1353.UMNK88_4136,iY75_1357.Y75_RS20365	AA_permease_2
CH3_k127_3409752_1	1510531.JQJJ01000010_gene2441	2.261e-118	396.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,2V9SJ@28211|Alphaproteobacteria,3JRUA@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Amino acid permease	MA20_31530	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
CH3_k127_3409752_6	765913.ThidrDRAFT_2565	7.529e-07	52.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,1RY8P@1236|Gammaproteobacteria,1WWGX@135613|Chromatiales	135613|Chromatiales	E	PFAM amino acid permease-associated region	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
CH3_k127_3409752_2	1454004.AW11_00497	4.148e-93	316.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,2VKBQ@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
CH3_k127_3409752_0	595536.ADVE02000001_gene3060	3.236e-212	691.0	COG0553@1|root,COG0553@2|Bacteria,1MV6M@1224|Proteobacteria,2TU4W@28211|Alphaproteobacteria,36Z5E@31993|Methylocystaceae	28211|Alphaproteobacteria	L	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
CH3_k127_3409752_5	420324.KI911932_gene324	1.123e-13	74.0	2EHAG@1|root,3394C@2|Bacteria,1NK4E@1224|Proteobacteria,2UJZB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Family of unknown function (DUF5372)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5372
CH3_k127_3411341_0	497964.CfE428DRAFT_6644	5.5e-241	763.0	COG1657@1|root,COG1657@2|Bacteria,46TK5@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Squalene-hopene cyclase N-terminal domain	sqhC	-	4.2.1.129,5.4.99.17	ko:K06045	ko00909,ko01110,map00909,map01110	-	R07322,R07323	RC01850,RC01851	ko00000,ko00001,ko01000	-	-	-	SQHop_cyclase_C,SQHop_cyclase_N
CH3_k127_3411341_1	338966.Ppro_2630	8.223e-57	208.0	COG0543@1|root,COG0543@2|Bacteria,1RF43@1224|Proteobacteria,42RQK@68525|delta/epsilon subdivisions,2WNJU@28221|Deltaproteobacteria,43U15@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
CH3_k127_3411341_2	273068.TTE1530	7.485e-27	111.0	COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,248CQ@186801|Clostridia,42FGV@68295|Thermoanaerobacterales	186801|Clostridia	F	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
CH3_k127_3416158_9	497964.CfE428DRAFT_2433	1.557e-90	306.0	COG2010@1|root,COG4654@1|root,COG2010@2|Bacteria,COG4654@2|Bacteria	2|Bacteria	C	Cytochrome c, class I	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,PSCyt1,PSCyt2,PSD1
CH3_k127_3416158_1	497964.CfE428DRAFT_3528	6.219e-255	792.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501,Laminin_G_3
CH3_k127_3416158_0	886293.Sinac_3371	1.528e-286	912.0	COG2010@1|root,COG2010@2|Bacteria,2IYIY@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
CH3_k127_3416158_17	497964.CfE428DRAFT_0110	4.871e-56	200.0	COG1595@1|root,COG1595@2|Bacteria,46VNT@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CH3_k127_3416158_14	497964.CfE428DRAFT_0111	1.057e-65	247.0	2CMJG@1|root,32SEZ@2|Bacteria,46T0G@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_3416158_11	1123288.SOV_3c03730	9.499e-79	272.0	COG1043@1|root,COG1043@2|Bacteria,1TQRI@1239|Firmicutes,4H2NG@909932|Negativicutes	909932|Negativicutes	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep,Hexapep_2
CH3_k127_3416158_6	240016.ABIZ01000001_gene4595	2.67e-147	481.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,46SG1@74201|Verrucomicrobia,2ITYH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	IM	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	fabZ	-	3.5.1.108,4.2.1.59	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	M00060,M00083	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	-	-	-	FabA,LpxC
CH3_k127_3416158_18	452637.Oter_0798	2.967e-52	197.0	COG0741@1|root,COG0741@2|Bacteria,46XU1@74201|Verrucomicrobia,3K83P@414999|Opitutae	414999|Opitutae	M	Transglycosylase SLT domain	-	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	SLT
CH3_k127_3416158_15	935845.JADQ01000029_gene1230	1.181e-63	240.0	COG2755@1|root,COG4257@1|root,COG5184@1|root,COG2755@2|Bacteria,COG4257@2|Bacteria,COG5184@2|Bacteria,1UZD4@1239|Firmicutes,4HD48@91061|Bacilli,26VBQ@186822|Paenibacillaceae	91061|Bacilli	DZ	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin-like,RCC1_2,SLH
CH3_k127_3416158_20	1288494.EBAPG3_19800	1.698e-18	89.0	COG1216@1|root,COG1216@2|Bacteria,1N5DV@1224|Proteobacteria,2WB4B@28216|Betaproteobacteria,372A6@32003|Nitrosomonadales	28216|Betaproteobacteria	S	glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CH3_k127_3416158_21	338963.Pcar_1313	2.519e-10	75.0	COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,42P4T@68525|delta/epsilon subdivisions,2WJR1@28221|Deltaproteobacteria,43S2F@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	AsmA-like C-terminal region	-	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA,AsmA_2,DUF748
CH3_k127_3416158_3	1396141.BATP01000030_gene3746	4.185e-228	717.0	COG1129@1|root,COG1129@2|Bacteria,46SG6@74201|Verrucomicrobia,2IV5X@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
CH3_k127_3416158_7	497964.CfE428DRAFT_3050	2.634e-130	424.0	COG1172@1|root,COG1172@2|Bacteria	2|Bacteria	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10560	ko02010,map02010	M00220	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.9	-	-	BPD_transp_2
CH3_k127_3416158_4	497964.CfE428DRAFT_3049	1.484e-157	502.0	COG1172@1|root,COG1172@2|Bacteria	2|Bacteria	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10559,ko:K10561	ko02010,map02010	M00220	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.9	-	-	BPD_transp_2,Peripla_BP_4
CH3_k127_3416158_23	28072.Nos7524_5534	9.837e-06	56.0	COG3511@1|root,COG3511@2|Bacteria,1GHGK@1117|Cyanobacteria,1HRDE@1161|Nostocales	1117|Cyanobacteria	M	phospholipase C	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_3416158_13	1396141.BATP01000060_gene4563	2.293e-68	252.0	COG0457@1|root,COG0457@2|Bacteria,46W3Y@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3,TPR_16
CH3_k127_3416158_5	497964.CfE428DRAFT_3048	6.389e-155	500.0	COG1879@1|root,COG1879@2|Bacteria,46TWY@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Periplasmic binding protein domain	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
CH3_k127_3416158_24	497964.CfE428DRAFT_5353	0.0009163	43.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,HATPase_c,HD_5,Response_reg,T2SSE_N
CH3_k127_3416158_16	886293.Sinac_0846	8.822e-63	228.0	COG0310@1|root,COG0310@2|Bacteria,2IZTS@203682|Planctomycetes	203682|Planctomycetes	P	PFAM cobalamin (vitamin B12) biosynthesis CbiM protein	-	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM,PDGLE
CH3_k127_3416158_19	675635.Psed_3353	8.258e-22	103.0	COG0619@1|root,COG0619@2|Bacteria,2GKQ7@201174|Actinobacteria,4E0T6@85010|Pseudonocardiales	201174|Actinobacteria	P	Cobalt transport protein	cbiQ	-	-	ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
CH3_k127_3416158_12	886293.Sinac_0844	1.294e-73	255.0	COG1122@1|root,COG1122@2|Bacteria,2IZ47@203682|Planctomycetes	203682|Planctomycetes	P	Part of an ABC transporter complex. Responsible for energy coupling to the transport system	-	-	-	ko:K02006,ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	ABC_tran
CH3_k127_3416158_10	452637.Oter_1576	8.09e-86	295.0	COG0598@1|root,COG0598@2|Bacteria,46VYH@74201|Verrucomicrobia,3K7J8@414999|Opitutae	414999|Opitutae	P	CorA-like Mg2+ transporter protein	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
CH3_k127_3416158_8	478741.JAFS01000002_gene392	2.788e-91	314.0	COG5000@1|root,COG5000@2|Bacteria,46S9Q@74201|Verrucomicrobia,37FXN@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	T	PAS domain	ntrB	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_8
CH3_k127_3416158_2	497964.CfE428DRAFT_5035	5.918e-244	765.0	COG1012@1|root,COG1012@2|Bacteria,46UJM@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
CH3_k127_3416158_22	1229487.AMYW01000001_gene3873	5.36e-06	54.0	COG3209@1|root,COG4886@1|root,COG5184@1|root,COG3209@2|Bacteria,COG4886@2|Bacteria,COG5184@2|Bacteria,4NMJ3@976|Bacteroidetes,1I2GQ@117743|Flavobacteriia,2P052@237|Flavobacterium	976|Bacteroidetes	M	leucine- rich repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	LRR_4,Laminin_G_3,RCC1,SprB
CH3_k127_3418194_1	509191.AEDB02000022_gene2935	4.452e-112	384.0	COG2006@1|root,COG2006@2|Bacteria,1VRZ8@1239|Firmicutes,24Z9V@186801|Clostridia,3WN5G@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362,Dockerin_1
CH3_k127_3418194_3	1396141.BATP01000045_gene1848	1.959e-07	65.0	COG2911@1|root,COG3866@1|root,COG4932@1|root,COG5267@1|root,COG2911@2|Bacteria,COG3866@2|Bacteria,COG4932@2|Bacteria,COG5267@2|Bacteria,46TJE@74201|Verrucomicrobia,2IVHT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
CH3_k127_3418194_2	1123277.KB893189_gene5243	7.965e-10	73.0	COG5337@1|root,COG5337@2|Bacteria,4NEH2@976|Bacteroidetes,47PGS@768503|Cytophagia	976|Bacteroidetes	M	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Fn3_assoc,LTD
CH3_k127_3418194_0	926550.CLDAP_17510	1.141e-175	594.0	COG5337@1|root,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
CH3_k127_3467357_3	478741.JAFS01000002_gene501	2.143e-47	187.0	COG2270@1|root,COG2270@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	MFS_1
CH3_k127_3467357_1	1379698.RBG1_1C00001G1529	3.644e-99	340.0	COG2304@1|root,COG2304@2|Bacteria,2NPUS@2323|unclassified Bacteria	2|Bacteria	S	IgA Peptidase M64	-	-	-	-	-	-	-	-	-	-	-	-	M64_N,Peptidase_M64
CH3_k127_3467357_2	756067.MicvaDRAFT_5451	1.663e-91	335.0	COG1361@1|root,COG2931@1|root,COG3210@1|root,COG4932@1|root,COG1361@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG4932@2|Bacteria,1G463@1117|Cyanobacteria,1H97Y@1150|Oscillatoriales	1117|Cyanobacteria	MQ	PFAM Collagen-binding surface protein Cna-like, B-type domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,HemolysinCabind,SdrD_B
CH3_k127_3467357_0	497964.CfE428DRAFT_3903	1.663e-163	532.0	COG1640@1|root,COG1640@2|Bacteria,46SX0@74201|Verrucomicrobia	74201|Verrucomicrobia	G	PFAM glycoside hydrolase family 77	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
CH3_k127_3486045_7	240016.ABIZ01000001_gene5569	7.243e-06	55.0	COG1053@1|root,COG1053@2|Bacteria,46S51@74201|Verrucomicrobia,2IVH2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	NAD(P)-binding Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
CH3_k127_3486045_6	1123277.KB893206_gene3466	2.834e-40	155.0	COG1621@1|root,COG1621@2|Bacteria,4NJ8X@976|Bacteroidetes,47N6D@768503|Cytophagia	976|Bacteroidetes	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
CH3_k127_3486045_3	999419.HMPREF1077_01244	6.942e-74	257.0	COG2273@1|root,COG2273@2|Bacteria,4P31M@976|Bacteroidetes,2G2G9@200643|Bacteroidia	976|Bacteroidetes	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
CH3_k127_3486045_1	497964.CfE428DRAFT_0023	1.441e-149	479.0	2EY4V@1|root,33RDN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_3486045_2	349521.HCH_01563	7.622e-123	400.0	COG0657@1|root,COG0657@2|Bacteria,1R4AU@1224|Proteobacteria,1RQMN@1236|Gammaproteobacteria,1XR8Q@135619|Oceanospirillales	135619|Oceanospirillales	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
CH3_k127_3486045_5	1121957.ATVL01000009_gene1157	3.927e-43	174.0	COG3940@1|root,COG3940@2|Bacteria,4PMI7@976|Bacteroidetes,47YEP@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolases family 43	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
CH3_k127_3486045_0	742727.HMPREF9447_01794	4.443e-203	661.0	COG3533@1|root,COG3533@2|Bacteria,4NFW3@976|Bacteroidetes,2FRKH@200643|Bacteroidia,4ARGS@815|Bacteroidaceae	976|Bacteroidetes	S	Beta-L-arabinofuranosidase, GH127	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
CH3_k127_3486045_4	537013.CLOSTMETH_01894	7.945e-70	247.0	COG1196@1|root,COG2273@1|root,COG3669@1|root,COG1196@2|Bacteria,COG2273@2|Bacteria,COG3669@2|Bacteria,1UFUR@1239|Firmicutes,25075@186801|Clostridia	2|Bacteria	DG	F5 8 type C domain protein	nagH	-	3.2.1.18,3.2.1.35,3.2.1.51	ko:K01186,ko:K01197,ko:K01206,ko:K21449	ko00511,ko00531,ko00600,ko01100,ko04142,map00511,map00531,map00600,map01100,map04142	M00076,M00077	R04018,R07824,R07825,R10905	RC00028,RC00077	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02000,ko02042,ko04147	1.B.40.2	GH29,GH33	-	Alpha_L_fucos,DUF4988,F5_F8_type_C,FIVAR,Glyco_hydro_106,Glyco_hydro_20b,NAGidase,RicinB_lectin_2
CH3_k127_3513678_4	497964.CfE428DRAFT_5469	3.891e-20	97.0	COG2067@1|root,COG2067@2|Bacteria,46SR3@74201|Verrucomicrobia	74201|Verrucomicrobia	I	PFAM membrane protein involved in aromatic hydrocarbon degradation	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
CH3_k127_3513678_5	1173026.Glo7428_2961	7.947e-16	89.0	COG3240@1|root,COG3240@2|Bacteria,1FZV1@1117|Cyanobacteria	1117|Cyanobacteria	I	Phospholipase lecithinase hemolysin	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL
CH3_k127_3513678_1	452637.Oter_0935	2.637e-153	494.0	COG0042@1|root,COG0042@2|Bacteria,46TCT@74201|Verrucomicrobia,3K895@414999|Opitutae	414999|Opitutae	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	-	-	-	-	-	-	-	-	-	Dus
CH3_k127_3513678_2	1297617.JPJD01000047_gene1362	1.047e-50	192.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,24FR4@186801|Clostridia,268EW@186813|unclassified Clostridiales	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
CH3_k127_3513678_6	383372.Rcas_2923	1.428e-12	70.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,2G6YQ@200795|Chloroflexi,376I2@32061|Chloroflexia	32061|Chloroflexia	H	PFAM molybdopterin biosynthesis MoaE protein	moaD	-	2.8.1.12	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
CH3_k127_3513678_3	1123388.AQWU01000068_gene1033	1.341e-23	105.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,1WIMD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	moaD	-	2.8.1.12	ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
CH3_k127_3513678_0	497964.CfE428DRAFT_3486	0.0	1713.0	COG1038@1|root,COG1038@2|Bacteria,46S8N@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Conserved carboxylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA
CH3_k127_3515745_3	1121957.ATVL01000014_gene1459	2.488e-149	509.0	COG5563@1|root,COG5563@2|Bacteria,4PHUI@976|Bacteroidetes,47VHU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_3515745_0	497964.CfE428DRAFT_1084	5.513e-302	945.0	COG1966@1|root,COG1966@2|Bacteria,46SC3@74201|Verrucomicrobia	74201|Verrucomicrobia	T	5TM C-terminal transporter carbon starvation CstA	-	-	-	-	-	-	-	-	-	-	-	-	CstA,CstA_5TM
CH3_k127_3515745_1	234267.Acid_6938	1.153e-150	488.0	COG5368@1|root,COG5368@2|Bacteria,3Y2MM@57723|Acidobacteria	57723|Acidobacteria	S	Putative glucoamylase	-	-	-	-	-	-	-	-	-	-	-	-	Glycoamylase
CH3_k127_3515745_5	452637.Oter_1760	6.265e-43	163.0	COG1057@1|root,COG1057@2|Bacteria,46T27@74201|Verrucomicrobia,3K85U@414999|Opitutae	414999|Opitutae	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
CH3_k127_3515745_7	1283299.AUKG01000005_gene41	2.02e-28	119.0	COG0799@1|root,COG0799@2|Bacteria,2IKZ3@201174|Actinobacteria,4CQDN@84995|Rubrobacteria	84995|Rubrobacteria	S	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
CH3_k127_3515745_8	1156937.MFUM_200030	6.367e-20	93.0	2DFNJ@1|root,2ZSFW@2|Bacteria,46WS2@74201|Verrucomicrobia,37HAT@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	PurA ssDNA and RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	PurA
CH3_k127_3515745_2	269799.Gmet_1302	8.428e-150	485.0	COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,42MK9@68525|delta/epsilon subdivisions,2WJ1C@28221|Deltaproteobacteria,43UHM@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	SMART Nucleotide binding protein, PINc	phoH1	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
CH3_k127_3515745_6	1403819.BATR01000061_gene1887	9.147e-41	162.0	COG0625@1|root,COG0625@2|Bacteria,46SQB@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Glutathione S-transferase, N-terminal domain	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_2,GST_N_3
CH3_k127_3515745_10	886293.Sinac_6824	6.501e-15	83.0	28WRV@1|root,2ZIRK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_3515745_9	257313.BP2758	1.427e-19	99.0	COG1430@1|root,COG1430@2|Bacteria,1MZBJ@1224|Proteobacteria,2VSCK@28216|Betaproteobacteria,3T4GB@506|Alcaligenaceae	28216|Betaproteobacteria	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
CH3_k127_3515745_4	452637.Oter_0618	8.059e-137	443.0	COG3591@1|root,COG3591@2|Bacteria,46UUQ@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Peptidase S46	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
CH3_k127_3579139_14	794903.OPIT5_25025	5.567e-79	278.0	COG0840@1|root,COG0840@2|Bacteria,46Y7J@74201|Verrucomicrobia,3K92D@414999|Opitutae	414999|Opitutae	NT	PFAM chemotaxis sensory transducer	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HBM,MCPsignal
CH3_k127_3579139_15	794903.OPIT5_24810	7.2e-76	264.0	COG1352@1|root,COG1352@2|Bacteria,46U98@74201|Verrucomicrobia,3K88R@414999|Opitutae	414999|Opitutae	NT	CheR methyltransferase, SAM binding domain	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
CH3_k127_3579139_11	166318.Syn8016DRAFT_1993	8.896e-104	353.0	COG2201@1|root,COG2201@2|Bacteria,1GJ7G@1117|Cyanobacteria,1H1FB@1129|Synechococcus	1117|Cyanobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
CH3_k127_3579139_21	278957.ABEA03000035_gene748	1.125e-34	137.0	COG0745@1|root,COG0745@2|Bacteria,46V0J@74201|Verrucomicrobia,3K7HQ@414999|Opitutae	414999|Opitutae	T	PFAM response regulator receiver	-	-	2.7.7.65	ko:K02488,ko:K02658	ko02020,ko02025,ko04112,map02020,map02025,map04112	M00507,M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035,ko02044	-	-	-	Response_reg
CH3_k127_3579139_9	696747.NIES39_E02730	5.309e-114	386.0	COG0745@1|root,COG2114@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG5002@2|Bacteria,1GHFQ@1117|Cyanobacteria,1HHU4@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	ko:K19694	-	-	-	-	ko00000,ko01001,ko02022	-	-	-	7TMR-DISM_7TM,Guanylate_cyc,HAMP,HATPase_c,HisKA,PAS_4,PAS_9,Response_reg,dCache_1
CH3_k127_3579139_23	1123401.JHYQ01000006_gene6	2.961e-29	126.0	COG1432@1|root,COG1432@2|Bacteria,1REF0@1224|Proteobacteria,1S545@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	NYN
CH3_k127_3579139_12	404589.Anae109_3433	3.205e-99	337.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WJ28@28221|Deltaproteobacteria,2YWA0@29|Myxococcales	28221|Deltaproteobacteria	NU	Type II/IV secretion system protein	pilT-1	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
CH3_k127_3579139_8	429009.Adeg_1724	2.547e-123	405.0	COG2805@1|root,COG2805@2|Bacteria,1TQ5F@1239|Firmicutes,249H9@186801|Clostridia,42F4T@68295|Thermoanaerobacterales	186801|Clostridia	NU	PFAM Type II secretion system protein E	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
CH3_k127_3579139_24	215803.DB30_7168	3.327e-17	93.0	COG0664@1|root,COG0664@2|Bacteria,1NBX3@1224|Proteobacteria,42UGQ@68525|delta/epsilon subdivisions,2WQY8@28221|Deltaproteobacteria,2YVI9@29|Myxococcales	28221|Deltaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
CH3_k127_3579139_26	102125.Xen7305DRAFT_00008790	4.08e-08	59.0	2CRRJ@1|root,32SPH@2|Bacteria,1GGJ1@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF3307)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3307
CH3_k127_3579139_25	497964.CfE428DRAFT_4116	5.587e-16	87.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CH3_k127_3579139_3	794903.OPIT5_19015	1.595e-161	525.0	COG0143@1|root,COG0143@2|Bacteria,46SCQ@74201|Verrucomicrobia,3K783@414999|Opitutae	414999|Opitutae	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1g
CH3_k127_3579139_10	497964.CfE428DRAFT_1406	6.478e-106	366.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,46S8W@74201|Verrucomicrobia	74201|Verrucomicrobia	P	PFAM CBS domain containing protein	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
CH3_k127_3579139_2	497964.CfE428DRAFT_0827	9.758e-174	556.0	COG2223@1|root,COG2223@2|Bacteria,46UH2@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CH3_k127_3579139_1	765952.PUV_14580	2.317e-302	939.0	COG0365@1|root,COG0365@2|Bacteria,2JFRM@204428|Chlamydiae	204428|Chlamydiae	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
CH3_k127_3579139_13	909663.KI867150_gene2007	3.11e-84	295.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,42NQP@68525|delta/epsilon subdivisions,2WIQD@28221|Deltaproteobacteria,2MR82@213462|Syntrophobacterales	28221|Deltaproteobacteria	BQ	PFAM histone deacetylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
CH3_k127_3579139_5	1173024.KI912153_gene217	6.604e-153	489.0	COG0167@1|root,COG0167@2|Bacteria,1G2B6@1117|Cyanobacteria,1JKMZ@1189|Stigonemataceae	1117|Cyanobacteria	F	Dihydroorotate dehydrogenase	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
CH3_k127_3579139_0	1173024.KI912153_gene216	0.0	1675.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1G2E2@1117|Cyanobacteria,1JKG2@1189|Stigonemataceae	1117|Cyanobacteria	C	Domain of unknown function	-	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C
CH3_k127_3579139_18	765420.OSCT_3130	7.545e-47	196.0	COG4932@1|root,COG5184@1|root,COG4932@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	ychO	GO:0005575,GO:0005623,GO:0008150,GO:0009279,GO:0009405,GO:0016020,GO:0019867,GO:0030260,GO:0030312,GO:0030313,GO:0031975,GO:0044403,GO:0044409,GO:0044419,GO:0044462,GO:0044464,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0071944	3.2.1.14	ko:K01183,ko:K20276	ko00520,ko01100,ko02024,map00520,map01100,map02024	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	He_PIG,IAT_beta,RCC1_2
CH3_k127_3579139_22	1123277.KB893172_gene995	2.126e-32	149.0	COG1520@1|root,COG3210@1|root,COG1520@2|Bacteria,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	ko:K02406,ko:K21449	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02000,ko02035	1.B.40.2	-	-	Beta_helix,DUF5122
CH3_k127_3579139_16	1499967.BAYZ01000068_gene1935	1.087e-69	272.0	COG3266@1|root,COG3420@1|root,COG4733@1|root,COG3266@2|Bacteria,COG3420@2|Bacteria,COG4733@2|Bacteria,2NS5M@2323|unclassified Bacteria	2|Bacteria	P	Fibronectin type 3 domain	-	-	-	ko:K12685,ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000,ko02044	1.B.12.5.1,1.B.12.5.3,3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CHB_HEX_C_1,CHU_C,DUF1573,DUF285,F5_F8_type_C,Laminin_G_3,Lectin_legB,fn3
CH3_k127_3579139_6	1123242.JH636434_gene3161	4.268e-151	486.0	COG1915@1|root,COG1915@2|Bacteria,2IXX9@203682|Planctomycetes	203682|Planctomycetes	S	PFAM LOR SDH bifunctional enzyme conserved region	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_3579139_7	497964.CfE428DRAFT_1935	1.285e-129	422.0	COG2870@1|root,COG2870@2|Bacteria	2|Bacteria	H	ADP-L-glycero-beta-D-manno-heptose biosynthetic process	-	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,Hydrolase,PfkB
CH3_k127_3579139_17	1304275.C41B8_01647	7.273e-65	229.0	COG0529@1|root,COG0529@2|Bacteria,1MX0D@1224|Proteobacteria,1RNWT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Catalyzes the synthesis of activated sulfate	cysC	-	2.7.1.25,2.7.7.4	ko:K00860,ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,ATP-sulfurylase,PUA_2
CH3_k127_3579139_4	243233.MCA2756	2.24e-156	501.0	COG0438@1|root,COG0438@2|Bacteria,1NMB5@1224|Proteobacteria,1RRVU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Sulfotransfer_3
CH3_k127_3579139_19	497964.CfE428DRAFT_5946	4.243e-41	161.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CH3_k127_3602804_2	794903.OPIT5_18315	1.299e-65	226.0	COG0176@1|root,COG0176@2|Bacteria,46UAK@74201|Verrucomicrobia,3K7KW@414999|Opitutae	414999|Opitutae	F	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
CH3_k127_3602804_1	1267535.KB906767_gene5199	1.329e-107	358.0	COG1082@1|root,COG1082@2|Bacteria,3Y78R@57723|Acidobacteria	57723|Acidobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CH3_k127_3602804_0	452637.Oter_2475	2.802e-251	787.0	COG0173@1|root,COG0173@2|Bacteria,46S7W@74201|Verrucomicrobia,3K79T@414999|Opitutae	414999|Opitutae	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
CH3_k127_3608461_0	1123242.JH636434_gene4307	1.122e-191	611.0	COG1032@1|root,COG1032@2|Bacteria,2J1W3@203682|Planctomycetes	203682|Planctomycetes	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4080,Radical_SAM
CH3_k127_3608461_4	1191523.MROS_0856	9.244e-57	203.0	COG2606@1|root,COG2606@2|Bacteria	2|Bacteria	S	Cys-tRNA(Pro) hydrolase activity	-	-	-	ko:K03976,ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
CH3_k127_3608461_7	1283283.ATXA01000005_gene2190	6.493e-05	48.0	COG0582@1|root,COG0582@2|Bacteria,2GMMI@201174|Actinobacteria,4ESQP@85013|Frankiales	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	int	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
CH3_k127_3608461_5	1123242.JH636434_gene4667	1.035e-44	177.0	2F56K@1|root,33XTB@2|Bacteria,2J30K@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_3608461_1	1267533.KB906733_gene3043	8.183e-181	582.0	COG1574@1|root,COG1574@2|Bacteria,3Y2UF@57723|Acidobacteria,2JIRH@204432|Acidobacteriia	204432|Acidobacteriia	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
CH3_k127_3608461_6	331869.BAL199_20935	2.04e-33	139.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2TR2B@28211|Alphaproteobacteria,4BSDR@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	COG0790 FOG TPR repeat, SEL1 subfamily	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
CH3_k127_3608461_2	886293.Sinac_6918	1.94e-107	364.0	COG2133@1|root,COG3386@1|root,COG2133@2|Bacteria,COG3386@2|Bacteria,2IXAF@203682|Planctomycetes	203682|Planctomycetes	G	glucose sorbosone	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	DUF1080,GSDH,SGL
CH3_k127_3608461_3	251221.35211841	5.793e-79	279.0	COG1404@1|root,COG1404@2|Bacteria,1G8UV@1117|Cyanobacteria	1117|Cyanobacteria	O	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8,VCBS
CH3_k127_3612020_2	261292.Nit79A3_2343	0.0001568	48.0	COG0028@1|root,COG0028@2|Bacteria	2|Bacteria	EH	Belongs to the TPP enzyme family	-	-	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	Laminin_G_3,PKD,TIG,TPP_enzyme_M,fn3
CH3_k127_3612020_0	497964.CfE428DRAFT_0021	2.145e-31	126.0	COG3668@1|root,COG3668@2|Bacteria,46WMW@74201|Verrucomicrobia	74201|Verrucomicrobia	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
CH3_k127_3612020_1	324602.Caur_2858	5.917e-24	111.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PKD,SBBP
CH3_k127_3626999_1	1499967.BAYZ01000012_gene2475	4.092e-42	158.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	ydjG	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0019170,GO:0055114	-	ko:K18471	ko00640,map00640	-	R10718	RC00739	ko00000,ko00001,ko01000	-	-	-	Aldo_ket_red
CH3_k127_3626999_0	882378.RBRH_00535	2.058e-112	380.0	COG0308@1|root,COG0308@2|Bacteria,1NQIW@1224|Proteobacteria,2WA6B@28216|Betaproteobacteria,1K252@119060|Burkholderiaceae	28216|Betaproteobacteria	E	beta subunit of N-acylethanolamine-hydrolyzing acid amidase	-	-	-	-	-	-	-	-	-	-	-	-	NAAA-beta,Phospholip_B
CH3_k127_3626999_2	880526.KE386488_gene1576	5.779e-23	115.0	COG0823@1|root,COG0823@2|Bacteria,4NIGD@976|Bacteroidetes,2G2P7@200643|Bacteroidia	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_3630367_0	382464.ABSI01000010_gene3621	2.121e-157	502.0	COG2960@1|root,COG2960@2|Bacteria,46UCE@74201|Verrucomicrobia,2IVAW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF1552)	-	-	-	-	-	-	-	-	-	-	-	-	HXXSHH
CH3_k127_3630367_1	935863.AWZR01000001_gene1970	1.346e-111	368.0	COG2382@1|root,COG2382@2|Bacteria,1NFUS@1224|Proteobacteria,1T816@1236|Gammaproteobacteria,1XA10@135614|Xanthomonadales	135614|Xanthomonadales	P	Putative esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase
CH3_k127_3647004_2	338966.Ppro_0910	3.763e-52	191.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,42QET@68525|delta/epsilon subdivisions,2WIZV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	AMP-binding enzyme	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
CH3_k127_3647004_1	1123008.KB905694_gene1758	6.929e-74	268.0	COG1216@1|root,COG3216@1|root,COG1216@2|Bacteria,COG3216@2|Bacteria,4NETR@976|Bacteroidetes,2FQIT@200643|Bacteroidia,22X2B@171551|Porphyromonadaceae	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase,DUF2062,Glycos_transf_2
CH3_k127_3647004_0	679935.Alfi_1534	6.594e-125	448.0	COG0204@1|root,COG2813@1|root,COG4258@1|root,COG0204@2|Bacteria,COG2813@2|Bacteria,COG4258@2|Bacteria,4PKBM@976|Bacteroidetes,2FQP4@200643|Bacteroidia	976|Bacteroidetes	I	Acyltransferase	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	Acyltransferase,MMPL,Methyltransf_25,Methyltransf_31
CH3_k127_3669393_4	158500.BV97_03464	1.256e-35	138.0	COG1479@1|root,COG1479@2|Bacteria,1N34S@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function DUF262	-	-	-	-	-	-	-	-	-	-	-	-	DUF262
CH3_k127_3669393_5	641524.ADICYQ_3837	3.616e-22	113.0	28MHM@1|root,2ZAUH@2|Bacteria,4NKMG@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_3669393_0	1403819.BATR01000114_gene3945	6.208e-207	653.0	COG3119@1|root,COG3119@2|Bacteria,46UET@74201|Verrucomicrobia,2IU4V@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	C-terminal region of aryl-sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,Sulfatase_C
CH3_k127_3669393_2	452637.Oter_2162	3.458e-172	544.0	COG1181@1|root,COG1181@2|Bacteria	2|Bacteria	F	Belongs to the D-alanine--D-alanine ligase family	ddlB1	-	6.3.2.4,6.3.5.5	ko:K01921,ko:K01955	ko00240,ko00250,ko00473,ko00550,ko01100,ko01502,map00240,map00250,map00473,map00550,map01100,map01502	M00051	R00256,R00575,R01150,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC00064,RC00141,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
CH3_k127_3669393_3	452637.Oter_2161	6.733e-57	199.0	COG4307@1|root,COG4307@2|Bacteria	2|Bacteria	T	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_Mx,zinc-ribbon_6
CH3_k127_3675804_0	886293.Sinac_7042	2.584e-226	728.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,2IX73@203682|Planctomycetes	203682|Planctomycetes	C	PFAM PBS lyase HEAT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,HEAT_2
CH3_k127_3675804_2	639030.JHVA01000001_gene3130	2.198e-12	74.0	2BIJA@1|root,32CS2@2|Bacteria,3Y9DG@57723|Acidobacteria	57723|Acidobacteria	S	CHRD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
CH3_k127_3675804_1	178901.AmDm5_2467	1.008e-125	415.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,2TQZU@28211|Alphaproteobacteria,2JQ9C@204441|Rhodospirillales	204441|Rhodospirillales	F	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
CH3_k127_3683574_1	497964.CfE428DRAFT_2770	1.637e-13	74.0	COG3071@1|root,COG3071@2|Bacteria	2|Bacteria	H	HemY protein	-	-	-	ko:K08309,ko:K11935,ko:K20543	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000,ko01011,ko02000	1.B.55.3	GH23	-	BCSC_C,TPR_12,TPR_16,TPR_19,TPR_6,TPR_8
CH3_k127_3683574_0	1122176.KB903598_gene4712	3.2e-118	410.0	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,CW_binding_1,HYR
CH3_k127_3704548_1	583355.Caka_1995	4.502e-97	336.0	COG0472@1|root,COG0472@2|Bacteria,46SNJ@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Glycosyl transferase family 4	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
CH3_k127_3704548_4	497964.CfE428DRAFT_3096	9.217e-44	166.0	COG0250@1|root,COG0250@2|Bacteria,46SYX@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Transcription termination factor nusG	-	-	-	ko:K05785	-	-	-	-	ko00000,ko03000	-	-	-	NusG
CH3_k127_3704548_0	497964.CfE428DRAFT_2775	1.423e-149	499.0	COG0489@1|root,COG0489@2|Bacteria,46UJ7@74201|Verrucomicrobia	74201|Verrucomicrobia	D	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
CH3_k127_3704548_3	497964.CfE428DRAFT_2774	1.276e-49	186.0	COG1596@1|root,COG1596@2|Bacteria,46VQY@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
CH3_k127_3704548_2	497964.CfE428DRAFT_2773	2.083e-53	205.0	2F6K4@1|root,33Z30@2|Bacteria,46VYC@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Putative beta-barrel porin 2	-	-	-	-	-	-	-	-	-	-	-	-	BBP2_2
CH3_k127_3708965_10	246199.CUS_5556	0.0008386	48.0	COG3209@1|root,COG5492@1|root,COG3209@2|Bacteria,COG5492@2|Bacteria,1TS8J@1239|Firmicutes,24A7I@186801|Clostridia,3WGX5@541000|Ruminococcaceae	186801|Clostridia	N	dockerin type I repeat-containing domain protein	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5,N_methyl
CH3_k127_3708965_6	1245471.PCA10_37690	1.102e-18	93.0	COG1595@1|root,COG1595@2|Bacteria,1N38X@1224|Proteobacteria,1SASQ@1236|Gammaproteobacteria,1YCT8@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CH3_k127_3708965_4	1123248.KB893329_gene4468	6.008e-36	138.0	COG4299@1|root,COG4299@2|Bacteria,4NH8T@976|Bacteroidetes,1IUWN@117747|Sphingobacteriia	976|Bacteroidetes	S	COGs COG4299 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF5009
CH3_k127_3708965_2	886293.Sinac_7036	6.964e-132	426.0	COG4299@1|root,COG4299@2|Bacteria,2IX5Y@203682|Planctomycetes	203682|Planctomycetes	S	COGs COG4299 conserved	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_3708965_8	555079.Toce_2158	1.698e-05	54.0	2E2B7@1|root,32XGJ@2|Bacteria,1UPQ4@1239|Firmicutes,25HKV@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_3708965_1	272123.Anacy_2354	6.358e-143	467.0	COG0436@1|root,COG0436@2|Bacteria,1G0M8@1117|Cyanobacteria,1HIFU@1161|Nostocales	1117|Cyanobacteria	E	PFAM Aminotransferase class I and II	aspC	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CH3_k127_3708965_7	661478.OP10G_0968	9.294e-15	85.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02650,ko:K02679	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10
CH3_k127_3708965_3	452637.Oter_2787	4.096e-50	191.0	COG0739@1|root,COG0739@2|Bacteria,46V20@74201|Verrucomicrobia,3K74E@414999|Opitutae	414999|Opitutae	M	Peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CH3_k127_3708965_5	452637.Oter_0650	4.443e-25	120.0	COG4726@1|root,COG4726@2|Bacteria,46YMK@74201|Verrucomicrobia,3K9UG@414999|Opitutae	414999|Opitutae	NU	Pilus assembly protein PilX	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_3708965_0	1480694.DC28_14620	7.086e-221	704.0	COG0187@1|root,COG0187@2|Bacteria,2J6PT@203691|Spirochaetes	203691|Spirochaetes	L	DNA topoisomerase	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
CH3_k127_3714711_4	1111479.AXAR01000001_gene213	8.371e-61	222.0	COG4221@1|root,COG4221@2|Bacteria,1TRHF@1239|Firmicutes,4HBXH@91061|Bacilli,278V8@186823|Alicyclobacillaceae	91061|Bacilli	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CH3_k127_3714711_2	521674.Plim_2636	4.165e-141	464.0	COG3250@1|root,COG3250@2|Bacteria,2J54D@203682|Planctomycetes	203682|Planctomycetes	G	Pfam:DUF303	-	-	3.1.1.53	ko:K05970	-	-	-	-	ko00000,ko01000	-	-	-	SASA
CH3_k127_3714711_1	497964.CfE428DRAFT_6471	9.558e-173	550.0	COG0508@1|root,COG0508@2|Bacteria,46UHU@74201|Verrucomicrobia	74201|Verrucomicrobia	C	2-oxoacid dehydrogenases acyltransferase (catalytic domain)	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
CH3_k127_3714711_0	497964.CfE428DRAFT_6472	5.509e-174	550.0	COG0022@1|root,COG0022@2|Bacteria,46UID@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
CH3_k127_3714711_3	497964.CfE428DRAFT_6473	3.736e-131	432.0	COG1071@1|root,COG1071@2|Bacteria,46UAY@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Dehydrogenase E1 component	-	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
CH3_k127_3714711_5	234267.Acid_6247	2.297e-43	167.0	COG0673@1|root,COG0673@2|Bacteria,3Y39X@57723|Acidobacteria	57723|Acidobacteria	S	PFAM oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CH3_k127_3734944_4	272624.lpg0358	4.046e-89	301.0	COG0623@1|root,COG0623@2|Bacteria,1N64Z@1224|Proteobacteria,1T3N8@1236|Gammaproteobacteria,1JC7V@118969|Legionellales	118969|Legionellales	I	KR domain	-	-	1.3.1.104	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R01404,R04430,R04725,R04956,R04959,R04962,R04967,R04970	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CH3_k127_3734944_6	344747.PM8797T_12848	4.638e-61	220.0	COG1028@1|root,COG1028@2|Bacteria,2IXE0@203682|Planctomycetes	203682|Planctomycetes	IQ	with different specificities (related to short-chain alcohol	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CH3_k127_3734944_7	272624.lpg0359	2.637e-41	159.0	COG0236@1|root,COG0236@2|Bacteria,1NM9E@1224|Proteobacteria,1SINP@1236|Gammaproteobacteria,1JEJN@118969|Legionellales	118969|Legionellales	IQ	Phosphopantetheine attachment site	acpP_2	-	-	-	-	-	-	-	-	-	-	-	PP-binding
CH3_k127_3734944_11	1122164.JHWF01000017_gene537	1.36e-20	102.0	COG0764@1|root,COG0764@2|Bacteria,1PCKD@1224|Proteobacteria,1SXNH@1236|Gammaproteobacteria,1JDAD@118969|Legionellales	118969|Legionellales	I	FabA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	FabA
CH3_k127_3734944_1	272624.lpg0361	1.873e-142	465.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,1JDCZ@118969|Legionellales	118969|Legionellales	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179,2.3.1.41	ko:K00647,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
CH3_k127_3734944_2	297246.lpp0427	5.978e-99	342.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,1JD6F@118969|Legionellales	118969|Legionellales	IQ	Beta-ketoacyl synthase, C-terminal domain	-	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
CH3_k127_3734944_5	1122165.AUHS01000023_gene237	1.046e-65	241.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,1RXSU@1236|Gammaproteobacteria,1JDJP@118969|Legionellales	118969|Legionellales	M	lipid A biosynthesis	waaM	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
CH3_k127_3734944_13	661478.OP10G_1142	8.907e-14	82.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02650,ko:K02679	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10
CH3_k127_3734944_8	452637.Oter_3202	1.441e-39	151.0	COG1869@1|root,COG1869@2|Bacteria,46VR5@74201|Verrucomicrobia	74201|Verrucomicrobia	G	RbsD / FucU transport protein family	-	-	5.4.99.62	ko:K06726	ko02010,map02010	-	R08247	RC02247	ko00000,ko00001,ko01000	-	-	-	RbsD_FucU
CH3_k127_3734944_0	1396141.BATP01000003_gene4934	1.309e-174	609.0	COG2312@1|root,COG2312@2|Bacteria	2|Bacteria	S	response to antibiotic	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Erythro_esteras,LTD
CH3_k127_3734944_12	1396141.BATP01000030_gene3719	2.661e-18	102.0	COG3119@1|root,COG3211@1|root,COG3656@1|root,COG5337@1|root,COG3119@2|Bacteria,COG3211@2|Bacteria,COG3656@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	phoX	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	CotH,DUF839
CH3_k127_3734944_9	497964.CfE428DRAFT_1216	8.747e-31	127.0	COG2018@1|root,COG2018@2|Bacteria	2|Bacteria	K	Roadblock/LC7 domain	mglB	-	-	-	-	-	-	-	-	-	-	-	Robl_LC7
CH3_k127_3734944_3	497964.CfE428DRAFT_1215	7.589e-95	316.0	COG1100@1|root,COG1100@2|Bacteria,46VDZ@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Ras family	-	-	-	-	-	-	-	-	-	-	-	-	Arf
CH3_k127_3736276_1	497964.CfE428DRAFT_4864	2.346e-58	211.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_3736276_0	886293.Sinac_6489	1.441e-140	483.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
CH3_k127_3750400_6	926564.KI911694_gene907	8.183e-07	57.0	COG1357@1|root,COG1357@2|Bacteria,2I0KS@201174|Actinobacteria,4F4KI@85017|Promicromonosporaceae	201174|Actinobacteria	S	Pentapeptide repeats (9 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
CH3_k127_3750400_5	1196323.ALKF01000152_gene1018	1.586e-26	117.0	2C4H4@1|root,32X9D@2|Bacteria,1VCB6@1239|Firmicutes,4HKJT@91061|Bacilli,26TSY@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_3750400_3	946483.Cenrod_1961	4.58e-41	157.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,2VMDU@28216|Betaproteobacteria,4AJA8@80864|Comamonadaceae	28216|Betaproteobacteria	L	Group II intron, maturase-specific domain	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,Intron_maturas2,RVT_1
CH3_k127_3750400_4	639030.JHVA01000001_gene2022	4.005e-37	149.0	COG3794@1|root,COG3794@2|Bacteria,3Y4C0@57723|Acidobacteria,2JJME@204432|Acidobacteriia	204432|Acidobacteriia	C	Polysaccharide lyase family 4, domain II	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CH3_k127_3750400_0	497964.CfE428DRAFT_0790	1.309e-187	597.0	COG3875@1|root,COG3875@2|Bacteria	2|Bacteria	S	lactate racemase activity	-	-	5.1.2.1	ko:K22373	ko00620,map00620	-	R01450	RC00519	ko00000,ko00001,ko01000	-	-	-	DUF2088
CH3_k127_3750400_2	497964.CfE428DRAFT_6140	2.426e-82	283.0	COG0515@1|root,COG0515@2|Bacteria,46UMT@74201|Verrucomicrobia	497964.CfE428DRAFT_6140|-	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_3750400_1	756272.Plabr_3925	3.94e-86	293.0	COG1028@1|root,COG1028@2|Bacteria,2IXFA@203682|Planctomycetes	203682|Planctomycetes	IQ	with different specificities (related to short-chain alcohol	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CH3_k127_375876_1	1396141.BATP01000036_gene3854	7.937e-110	361.0	COG0673@1|root,COG0673@2|Bacteria,46SAE@74201|Verrucomicrobia,2IU1W@203494|Verrucomicrobiae	2|Bacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CH3_k127_375876_2	1396141.BATP01000036_gene3853	2.914e-52	194.0	COG2148@1|root,COG2148@2|Bacteria,46TSZ@74201|Verrucomicrobia,2ITYD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
CH3_k127_375876_0	317936.Nos7107_1299	1.269e-177	566.0	COG0579@1|root,COG0579@2|Bacteria,1G0XV@1117|Cyanobacteria,1HIW2@1161|Nostocales	1117|Cyanobacteria	S	PFAM FAD dependent oxidoreductase	-	-	-	ko:K15736	-	-	-	-	ko00000,ko01000	-	-	-	DAO
CH3_k127_375876_3	887898.HMPREF0551_0058	3.029e-42	156.0	COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,2VJAD@28216|Betaproteobacteria,1K19M@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
CH3_k127_3768244_0	595460.RRSWK_04184	1.42e-149	493.0	COG2804@1|root,COG2804@2|Bacteria,2IYEE@203682|Planctomycetes	203682|Planctomycetes	NU	COG2804 Type II secretory pathway ATPase PulE Tfp pilus assembly pathway ATPase PilB	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
CH3_k127_3798212_0	1123276.KB893262_gene4089	3.19e-86	289.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
CH3_k127_3798212_3	1123020.AUIE01000005_gene4447	4.238e-25	108.0	COG0346@1|root,COG0346@2|Bacteria,1RHZT@1224|Proteobacteria,1S679@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Glyoxalase_2
CH3_k127_3798212_6	404589.Anae109_2405	9.387e-05	55.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	ccoP	-	-	ko:K00406,ko:K08906	ko00190,ko00195,ko01100,ko02020,map00190,map00195,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko00194	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
CH3_k127_3798212_5	404589.Anae109_2405	6.13e-10	66.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	ccoP	-	-	ko:K00406,ko:K08906	ko00190,ko00195,ko01100,ko02020,map00190,map00195,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko00194	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
CH3_k127_3798212_2	1198452.Jab_1c17570	1.473e-26	116.0	2DP2V@1|root,330AH@2|Bacteria,1R3EE@1224|Proteobacteria,2WFSH@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF3455)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3455
CH3_k127_3798212_1	324057.Pjdr2_0886	2.512e-39	158.0	COG1470@1|root,COG3210@1|root,COG4447@1|root,COG4932@1|root,COG5492@1|root,COG1470@2|Bacteria,COG3210@2|Bacteria,COG4447@2|Bacteria,COG4932@2|Bacteria,COG5492@2|Bacteria,1TR9M@1239|Firmicutes,4HEPP@91061|Bacilli,26T62@186822|Paenibacillaceae	91061|Bacilli	U	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CBM_X2,CHB_HEX_C_1,Cadherin-like,Flg_new,SLH,fn3
CH3_k127_3798212_4	1125701.HMPREF1221_01616	7.494e-16	91.0	COG2407@1|root,COG2407@2|Bacteria	2|Bacteria	G	Converts the aldose L-fucose into the corresponding ketose L-fuculose	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_3799815_14	1237500.ANBA01000014_gene5634	2.71e-12	74.0	COG5433@1|root,COG5433@2|Bacteria,2HYBN@201174|Actinobacteria	201174|Actinobacteria	L	required for the transposition of insertion element IS2404	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
CH3_k127_3799815_9	380394.Lferr_0309	1.312e-64	242.0	COG5433@1|root,COG5433@2|Bacteria,1RAHU@1224|Proteobacteria,1S1TZ@1236|Gammaproteobacteria,2NDWK@225057|Acidithiobacillales	1236|Gammaproteobacteria	L	DDE_Tnp_1-associated	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc,DUF4338
CH3_k127_3799815_12	278957.ABEA03000091_gene684	1.516e-43	164.0	COG0499@1|root,COG0499@2|Bacteria,46SGX@74201|Verrucomicrobia,3K76U@414999|Opitutae	414999|Opitutae	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
CH3_k127_3799815_8	1469607.KK073768_gene3614	2.042e-82	282.0	COG3293@1|root,COG3293@2|Bacteria,1G0BW@1117|Cyanobacteria,1HNSC@1161|Nostocales	1117|Cyanobacteria	L	transposase	-	-	-	ko:K07492	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
CH3_k127_3799815_16	1463825.JNXC01000053_gene31	1.451e-05	55.0	COG3507@1|root,COG3507@2|Bacteria,2I911@201174|Actinobacteria,4E0PM@85010|Pseudonocardiales	201174|Actinobacteria	G	Cellulose Binding Domain Type IV	-	-	3.2.1.55	ko:K15921	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	CBM6,GH43	-	CBM_4_9,CBM_6,Glyco_hydro_43
CH3_k127_3799815_4	1396141.BATP01000060_gene4560	2.539e-132	446.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,46UAE@74201|Verrucomicrobia,2IV44@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_12,WD40
CH3_k127_3799815_13	111781.Lepto7376_3756	7.031e-27	126.0	COG1572@1|root,COG3209@1|root,COG3210@1|root,COG1572@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	3.2.1.78	ko:K01218	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000	-	GH26	-	CARDB,RHS_repeat
CH3_k127_3799815_7	497964.CfE428DRAFT_6357	2.006e-84	286.0	COG3176@1|root,COG3176@2|Bacteria,46UGN@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5
CH3_k127_3799815_11	880070.Cycma_1815	1.218e-52	192.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA,AhpC-TSA_2
CH3_k127_3799815_15	948106.AWZT01000019_gene3975	3.641e-08	59.0	COG5660@1|root,COG5660@2|Bacteria,1NH4R@1224|Proteobacteria,2VXXB@28216|Betaproteobacteria,1K9C3@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
CH3_k127_3799815_17	1387312.BAUS01000002_gene286	3.742e-05	53.0	COG5660@1|root,COG5660@2|Bacteria,1NH4R@1224|Proteobacteria,2W81G@28216|Betaproteobacteria,2KNB0@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
CH3_k127_3799815_10	497964.CfE428DRAFT_5990	1.136e-60	218.0	COG1595@1|root,COG1595@2|Bacteria,46W20@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CH3_k127_3799815_6	716544.wcw_0442	1.225e-125	409.0	COG1028@1|root,COG1028@2|Bacteria,2JG7F@204428|Chlamydiae	204428|Chlamydiae	IQ	KR domain	-	-	1.1.1.47	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	-	R01520,R01521	RC00066	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
CH3_k127_3799815_2	1496688.ER33_11555	4.723e-250	789.0	COG3408@1|root,COG3408@2|Bacteria,1G2AS@1117|Cyanobacteria,22THV@167375|Cyanobium	1117|Cyanobacteria	G	Amylo-alpha-1,6-glucosidase	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N
CH3_k127_3799815_0	1454004.AW11_02080	0.0	1355.0	COG0166@1|root,COG0166@2|Bacteria,1PQU4@1224|Proteobacteria,2VKX3@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Belongs to the GPI family	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_3799815_5	1121920.AUAU01000005_gene1032	7.462e-129	421.0	COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,3Y4JU@57723|Acidobacteria	57723|Acidobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	-	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
CH3_k127_3799815_3	641491.DND132_2614	1.333e-152	496.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,42MKS@68525|delta/epsilon subdivisions,2WKIH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	PFAM amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
CH3_k127_3799815_1	876044.IMCC3088_2538	1.287e-252	792.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,1RYI9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG3653 N-acyl-D-aspartate D-glutamate deacylase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
CH3_k127_3800207_0	530564.Psta_3017	4.307e-255	801.0	COG1053@1|root,COG1053@2|Bacteria,2IXHQ@203682|Planctomycetes	203682|Planctomycetes	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
CH3_k127_3800207_2	926549.KI421517_gene3311	1.114e-40	175.0	COG1520@1|root,COG3210@1|root,COG3405@1|root,COG1520@2|Bacteria,COG3210@2|Bacteria,COG3405@2|Bacteria,4NNUN@976|Bacteroidetes,47Q36@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
CH3_k127_3800207_3	1291050.JAGE01000002_gene3876	1.099e-26	129.0	COG1404@1|root,COG1404@2|Bacteria,1TQRU@1239|Firmicutes,249H1@186801|Clostridia,3WIWU@541000|Ruminococcaceae	186801|Clostridia	O	Subtilase family	-	-	-	ko:K13276,ko:K17734	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	CarboxypepD_reg,Cu_amine_oxidN1,Inhibitor_I9,LRR_5,PPC,Peptidase_S8
CH3_k127_3800207_4	103733.JNYO01000007_gene5239	6.016e-05	57.0	COG1404@1|root,COG1404@2|Bacteria,2GK3D@201174|Actinobacteria,4E1H7@85010|Pseudonocardiales	201174|Actinobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
CH3_k127_3800207_1	497964.CfE428DRAFT_2672	2.806e-189	602.0	COG0043@1|root,COG0043@2|Bacteria,46TYE@74201|Verrucomicrobia	74201|Verrucomicrobia	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	ubiD	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
CH3_k127_3808396_2	1122179.KB890442_gene1152	7.148e-46	173.0	COG5337@1|root,COG5337@2|Bacteria,4NI4U@976|Bacteroidetes	976|Bacteroidetes	M	COG5337 Spore coat assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
CH3_k127_3808396_5	237368.SCABRO_02994	3.768e-26	118.0	COG2930@1|root,COG2930@2|Bacteria,2IZZF@203682|Planctomycetes	203682|Planctomycetes	S	Las17-binding protein actin regulator	-	-	-	-	-	-	-	-	-	-	-	-	Ysc84
CH3_k127_3808396_0	1156937.MFUM_1020047	9.591e-85	300.0	COG4591@1|root,COG4591@2|Bacteria,46SKZ@74201|Verrucomicrobia,37G6B@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	MacB-like periplasmic core domain	lolE	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
CH3_k127_3808396_1	598467.BrE312_1653	3.236e-68	238.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,1RMWK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	Part of the ABC transporter complex LolCDE involved in the translocation of	lolD	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0015399,GO:0015405,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051234,GO:0051641,GO:0055085,GO:0070727,GO:0071944,GO:0072657,GO:0089705,GO:0097159,GO:0097367,GO:0098796,GO:0098797,GO:1901265,GO:1901363,GO:1990778	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
CH3_k127_3808396_3	497964.CfE428DRAFT_3025	1.647e-43	168.0	COG0500@1|root,COG0500@2|Bacteria,46SYP@74201|Verrucomicrobia	74201|Verrucomicrobia	Q	Thiopurine S-methyltransferase (TPMT)	-	-	-	-	-	-	-	-	-	-	-	-	TPMT
CH3_k127_3808396_4	857087.Metme_1435	7.955e-29	133.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria	1224|Proteobacteria	M	TIGRFAM YD repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat,Transglut_core
CH3_k127_3814574_1	3218.PP1S136_224V6.1	5.853e-05	54.0	COG0739@1|root,2S9HN@2759|Eukaryota,37YAK@33090|Viridiplantae,3GP6P@35493|Streptophyta	35493|Streptophyta	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CH3_k127_3814574_0	886293.Sinac_7037	9.469e-142	464.0	COG1073@1|root,COG1073@2|Bacteria,2IWT8@203682|Planctomycetes	203682|Planctomycetes	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_3821943_2	1189612.A33Q_1146	1.012e-147	480.0	COG3104@1|root,COG3104@2|Bacteria,4NE8R@976|Bacteroidetes,47JX4@768503|Cytophagia	976|Bacteroidetes	E	TIGRFAM amino acid peptide transporter (Peptide H symporter), bacterial	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
CH3_k127_3821943_1	240016.ABIZ01000001_gene4794	8.75e-165	530.0	COG0006@1|root,COG0006@2|Bacteria,46U30@74201|Verrucomicrobia,2ITPD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminopeptidase P, N-terminal domain	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
CH3_k127_3821943_3	313612.L8106_03564	1.937e-12	69.0	COG0598@1|root,COG0598@2|Bacteria,1G4WV@1117|Cyanobacteria,1HEGB@1150|Oscillatoriales	1117|Cyanobacteria	P	CorA-like Mg2+ transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	CorA
CH3_k127_3821943_0	497964.CfE428DRAFT_1398	6.249e-267	848.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,46U11@74201|Verrucomicrobia	74201|Verrucomicrobia	CG	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
CH3_k127_3867489_3	700598.Niako_3627	2.476e-38	146.0	COG0697@1|root,2Z7ID@2|Bacteria,4NEHB@976|Bacteroidetes,1IVNN@117747|Sphingobacteriia	976|Bacteroidetes	EG	L-rhamnose-proton symport protein (RhaT)	rhaT	-	-	ko:K02856	-	-	-	-	ko00000,ko02000	2.A.7.6	-	-	RhaT
CH3_k127_3867489_2	203275.BFO_2526	1.386e-44	164.0	COG3254@1|root,COG3254@2|Bacteria,4NQQ9@976|Bacteroidetes,2FTDQ@200643|Bacteroidia,22Z1W@171551|Porphyromonadaceae	976|Bacteroidetes	G	L-rhamnose mutarotase	-	-	5.1.3.32	ko:K03534	-	-	R10819	RC00563	ko00000,ko01000	-	-	-	rhaM
CH3_k127_3867489_0	344747.PM8797T_02169	5.488e-254	816.0	COG1409@1|root,COG1520@1|root,COG1409@2|Bacteria,COG1520@2|Bacteria,2IXB6@203682|Planctomycetes	203682|Planctomycetes	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,Metallophos,Methyltransf_25,PQQ_2
CH3_k127_3867489_1	344747.PM8797T_02174	1.148e-120	405.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
CH3_k127_3875161_0	237368.SCABRO_00954	5.296e-191	609.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_4
CH3_k127_3875161_4	243233.MCA2974	0.0001974	54.0	COG3291@1|root,COG5563@1|root,COG3291@2|Bacteria,COG5563@2|Bacteria,1QXQ7@1224|Proteobacteria,1T3G4@1236|Gammaproteobacteria,1XGBG@135618|Methylococcales	135618|Methylococcales	M	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_3875161_3	1123242.JH636435_gene1741	9.033e-16	88.0	COG2165@1|root,COG2165@2|Bacteria,2IYZV@203682|Planctomycetes	203682|Planctomycetes	NU	Protein of unknown function (DUF1559)	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CH3_k127_3875161_2	1303518.CCALI_02493	3.22e-18	94.0	COG4969@1|root,COG4969@2|Bacteria	2|Bacteria	NU	cell adhesion	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,SBP_bac_10
CH3_k127_3875161_1	1045855.DSC_09435	2.205e-24	104.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,1S8WZ@1236|Gammaproteobacteria,1X7HF@135614|Xanthomonadales	135614|Xanthomonadales	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
CH3_k127_3891494_10	69042.WH5701_09545	1.241e-51	186.0	COG3119@1|root,COG3119@2|Bacteria,1G3QV@1117|Cyanobacteria,1GZW2@1129|Synechococcus	1117|Cyanobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
CH3_k127_3891494_3	1268068.PG5_33320	4.945e-107	362.0	COG2067@1|root,COG2067@2|Bacteria,1R3SS@1224|Proteobacteria,1S0X2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	long-chain fatty acid transport protein	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
CH3_k127_3891494_9	525897.Dbac_1089	6.626e-55	199.0	2E9FY@1|root,333P7@2|Bacteria,1N8S6@1224|Proteobacteria,42XWP@68525|delta/epsilon subdivisions,2WSIE@28221|Deltaproteobacteria,2MFM6@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_3891494_6	575540.Isop_2535	4.759e-75	262.0	COG0580@1|root,COG0580@2|Bacteria,2IZDN@203682|Planctomycetes	203682|Planctomycetes	U	Belongs to the MIP aquaporin (TC 1.A.8) family	-	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
CH3_k127_3891494_12	522306.CAP2UW1_1267	1.6e-18	93.0	2EBP0@1|root,335P6@2|Bacteria,1N33Y@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_3891494_1	1123242.JH636436_gene23	1.339e-153	501.0	COG1335@1|root,COG1413@1|root,COG2010@1|root,COG2133@1|root,COG3828@1|root,COG1335@2|Bacteria,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,COG3828@2|Bacteria,2IX4V@203682|Planctomycetes	203682|Planctomycetes	C	COG2133 Glucose sorbosone dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
CH3_k127_3891494_11	761193.Runsl_2772	2.366e-49	188.0	COG0329@1|root,COG0329@2|Bacteria,4NI1I@976|Bacteroidetes,47NMJ@768503|Cytophagia	976|Bacteroidetes	EM	Dihydrodipicolinate synthetase family	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
CH3_k127_3891494_8	234267.Acid_5864	2.582e-57	213.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CH3_k127_3891494_7	583355.Caka_0200	3.24e-69	249.0	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_4,Kelch_6
CH3_k127_3891494_0	1123278.KB893563_gene4551	2.073e-255	811.0	COG3507@1|root,COG3507@2|Bacteria,4NEVJ@976|Bacteroidetes,47JBZ@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,CBM_6,Glyco_hydro_43
CH3_k127_3891494_4	661478.OP10G_2561	1.972e-95	342.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,Cellulase,Lipase_GDSL_2,PA14,RicinB_lectin_2
CH3_k127_3891494_5	926566.Terro_1270	2.223e-83	292.0	COG3693@1|root,COG3693@2|Bacteria,3Y6EW@57723|Acidobacteria	57723|Acidobacteria	G	Glycosyl hydrolase family 10	-	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_10
CH3_k127_3891494_2	1396141.BATP01000001_gene5356	6.571e-144	467.0	COG2382@1|root,COG2382@2|Bacteria,46YZE@74201|Verrucomicrobia,2IU0Q@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
CH3_k127_3902820_13	903818.KI912269_gene546	7.693e-11	63.0	COG0722@1|root,COG0722@2|Bacteria,3Y2HE@57723|Acidobacteria	57723|Acidobacteria	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	-	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
CH3_k127_3902820_6	290318.Cvib_1481	1.743e-44	164.0	COG0139@1|root,COG0139@2|Bacteria,1FE2H@1090|Chlorobi	1090|Chlorobi	F	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19	ko:K01496	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04037	RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH
CH3_k127_3902820_10	111780.Sta7437_1368	5.433e-21	98.0	COG2319@1|root,COG2319@2|Bacteria,1G309@1117|Cyanobacteria,3VMHR@52604|Pleurocapsales	1117|Cyanobacteria	S	PFAM WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	WD40
CH3_k127_3902820_15	41431.PCC8801_0934	3.455e-08	59.0	COG2319@1|root,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,3KJA0@43988|Cyanothece	1117|Cyanobacteria	S	PFAM WD-40 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHASE2,Peptidase_C14,TIR_2,WD40
CH3_k127_3902820_16	448385.sce1953	1.137e-05	58.0	COG4447@1|root,COG4447@2|Bacteria,1MVIT@1224|Proteobacteria,42S9Y@68525|delta/epsilon subdivisions,2WNFW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CH3_k127_3902820_5	382464.ABSI01000011_gene3178	8.325e-56	217.0	2BHTK@1|root,32BX8@2|Bacteria,46XA7@74201|Verrucomicrobia,2IV68@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_3902820_3	382464.ABSI01000011_gene3178	3.732e-87	314.0	2BHTK@1|root,32BX8@2|Bacteria,46XA7@74201|Verrucomicrobia,2IV68@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_3902820_7	382464.ABSI01000011_gene3178	7.274e-37	141.0	2BHTK@1|root,32BX8@2|Bacteria,46XA7@74201|Verrucomicrobia,2IV68@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_3902820_9	382464.ABSI01000011_gene3177	4.666e-31	128.0	2AWPW@1|root,31NKT@2|Bacteria,46WZA@74201|Verrucomicrobia,2IVVN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_3902820_14	382464.ABSI01000011_gene3177	1.061e-09	64.0	2AWPW@1|root,31NKT@2|Bacteria,46WZA@74201|Verrucomicrobia,2IVVN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_3902820_8	382464.ABSI01000010_gene3256	2.896e-32	134.0	COG2849@1|root,COG2849@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	MAF_flag10,MORN,MORN_2
CH3_k127_3902820_2	234267.Acid_2676	2.45e-165	529.0	COG0620@1|root,COG0620@2|Bacteria,3Y8ZA@57723|Acidobacteria	57723|Acidobacteria	E	Cobalamin-independent synthase, Catalytic domain	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
CH3_k127_3902820_1	1340493.JNIF01000004_gene602	2.195e-187	604.0	COG0823@1|root,COG0823@2|Bacteria,3Y6DB@57723|Acidobacteria	57723|Acidobacteria	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
CH3_k127_3902820_0	1267533.KB906738_gene2186	6.657e-289	902.0	COG1529@1|root,COG1529@2|Bacteria,3Y3J7@57723|Acidobacteria	57723|Acidobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C2
CH3_k127_3902820_4	1267533.KB906738_gene2187	6.181e-58	205.0	COG2080@1|root,COG2080@2|Bacteria,3Y5EJ@57723|Acidobacteria	57723|Acidobacteria	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
CH3_k127_3902820_12	889378.Spiaf_1653	4.312e-15	79.0	2EH48@1|root,33AW7@2|Bacteria,2J921@203691|Spirochaetes	203691|Spirochaetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_3902820_11	497964.CfE428DRAFT_4116	6.668e-19	95.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CH3_k127_3943349_0	762903.Pedsa_2424	8.441e-104	376.0	COG3209@1|root,COG3210@1|root,COG3291@1|root,COG4733@1|root,COG5492@1|root,COG3209@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria,COG5492@2|Bacteria,4NDZC@976|Bacteroidetes,1J0Y4@117747|Sphingobacteriia	976|Bacteroidetes	M	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SprB,TIG
CH3_k127_3943349_1	1150599.MPHLEI_02793	4.998e-29	136.0	COG3209@1|root,COG3209@2|Bacteria,2I60K@201174|Actinobacteria,2375A@1762|Mycobacteriaceae	201174|Actinobacteria	M	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,RCC1_2
CH3_k127_3943349_2	243231.GSU0754	1.333e-18	102.0	COG2373@1|root,COG2931@1|root,COG3210@1|root,COG3637@1|root,COG4625@1|root,COG2373@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3637@2|Bacteria,COG4625@2|Bacteria,1QWN8@1224|Proteobacteria,42TGT@68525|delta/epsilon subdivisions,2WQPA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_3959113_11	1341181.FLJC2902T_15110	1.669e-60	230.0	COG3386@1|root,COG3386@2|Bacteria,4PKPT@976|Bacteroidetes,1IKDI@117743|Flavobacteriia,2P0DY@237|Flavobacterium	976|Bacteroidetes	G	Domain of unknown function (DUF5122) beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122
CH3_k127_3959113_3	1121104.AQXH01000001_gene1014	6.228e-88	303.0	COG1785@1|root,COG1785@2|Bacteria,4NG3D@976|Bacteroidetes,1IPXF@117747|Sphingobacteriia	976|Bacteroidetes	P	Belongs to the alkaline phosphatase family	-	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase
CH3_k127_3959113_16	1348657.M622_01280	7.812e-17	95.0	COG3291@1|root,COG3291@2|Bacteria,1QUSE@1224|Proteobacteria	1224|Proteobacteria	G	PFAM FecR protein	-	-	3.2.1.4	ko:K01179,ko:K03933	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	AA10,CBM73,GH5,GH9	-	CBM_2,Calx-beta,Cellulase,PKD
CH3_k127_3959113_8	452637.Oter_2422	1.587e-67	236.0	COG1595@1|root,COG1595@2|Bacteria,46VAN@74201|Verrucomicrobia	74201|Verrucomicrobia	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
CH3_k127_3959113_0	1396141.BATP01000060_gene4560	3.355e-233	754.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,46UAE@74201|Verrucomicrobia,2IV44@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_12,WD40
CH3_k127_3959113_18	43989.cce_4844	2.546e-06	58.0	2A2DT@1|root,30QQT@2|Bacteria,1GM8B@1117|Cyanobacteria,3KJT1@43988|Cyanothece	1117|Cyanobacteria	S	PEP-CTERM motif	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
CH3_k127_3959113_15	349741.Amuc_0423	6.43e-21	99.0	COG0054@1|root,COG0054@2|Bacteria,46T5S@74201|Verrucomicrobia,2IUDV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
CH3_k127_3959113_1	497964.CfE428DRAFT_4667	1.5e-179	572.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,46S5K@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribB	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
CH3_k127_3959113_12	639030.JHVA01000001_gene2022	6.149e-42	164.0	COG3794@1|root,COG3794@2|Bacteria,3Y4C0@57723|Acidobacteria,2JJME@204432|Acidobacteriia	204432|Acidobacteriia	C	Polysaccharide lyase family 4, domain II	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CH3_k127_3959113_9	478741.JAFS01000001_gene1116	2.292e-66	244.0	COG1612@1|root,COG1612@2|Bacteria,46T3F@74201|Verrucomicrobia,37G83@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	O	Cytochrome oxidase assembly protein	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
CH3_k127_3959113_6	234267.Acid_4382	7.255e-76	265.0	COG0109@1|root,COG0109@2|Bacteria,3Y3VI@57723|Acidobacteria	57723|Acidobacteria	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
CH3_k127_3959113_2	382464.ABSI01000010_gene3668	2.09e-160	526.0	COG0843@1|root,COG0843@2|Bacteria,46S4Q@74201|Verrucomicrobia,2ITKY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Cytochrome C and Quinol oxidase polypeptide I	-	-	-	-	-	-	-	-	-	-	-	-	COX1
CH3_k127_3959113_5	481448.Minf_1950	1.248e-85	291.0	COG1845@1|root,COG1845@2|Bacteria,46SRD@74201|Verrucomicrobia,37FZZ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	Cytochrome c oxidase subunit III	cyoC	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
CH3_k127_3959113_17	1396141.BATP01000045_gene1834	4.483e-08	60.0	2DR0H@1|root,339NS@2|Bacteria,46ZIA@74201|Verrucomicrobia,2IUYZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Prokaryotic Cytochrome C oxidase subunit IV	-	-	-	-	-	-	-	-	-	-	-	-	COX4_pro
CH3_k127_3959113_7	497964.CfE428DRAFT_2235	7.857e-69	242.0	COG1622@1|root,COG1622@2|Bacteria,46SPQ@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Cytochrome C oxidase subunit II, periplasmic domain	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2
CH3_k127_3959113_14	1123508.JH636448_gene7577	2.296e-30	128.0	COG1999@1|root,COG1999@2|Bacteria,2IZH2@203682|Planctomycetes	203682|Planctomycetes	S	SCO1/SenC	-	-	-	ko:K07152,ko:K08976	-	-	-	-	ko00000,ko03029	-	-	-	DUF420,SCO1-SenC
CH3_k127_3959113_13	1279038.KB907352_gene2224	2.78e-31	128.0	COG2322@1|root,COG2322@2|Bacteria,1N3YI@1224|Proteobacteria,2UJ8D@28211|Alphaproteobacteria,2JX8I@204441|Rhodospirillales	204441|Rhodospirillales	S	Protein of unknown function (DUF420)	-	-	-	ko:K08976	-	-	-	-	ko00000	-	-	-	DUF420
CH3_k127_3959113_4	313612.L8106_20308	7.199e-86	296.0	COG4301@1|root,COG4301@2|Bacteria,1G4VW@1117|Cyanobacteria,1HF60@1150|Oscillatoriales	1117|Cyanobacteria	S	Histidine-specific methyltransferase, SAM-dependent	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_33
CH3_k127_3959113_10	203124.Tery_0699	3.366e-61	213.0	COG0294@1|root,COG0294@2|Bacteria,1G4A8@1117|Cyanobacteria,1HA6P@1150|Oscillatoriales	1117|Cyanobacteria	H	synthase	-	-	-	-	-	-	-	-	-	-	-	-	Pterin_bind
CH3_k127_3966998_1	1121481.AUAS01000001_gene4367	1.929e-70	243.0	COG1082@1|root,COG1082@2|Bacteria,4NJF5@976|Bacteroidetes,47MRZ@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
CH3_k127_3966998_0	742725.HMPREF9450_00266	1.173e-226	725.0	COG3408@1|root,COG3408@2|Bacteria,4NJY8@976|Bacteroidetes,2G2N9@200643|Bacteroidia	976|Bacteroidetes	G	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
CH3_k127_3985123_7	1300143.CCAV010000008_gene3389	2.471e-05	55.0	COG5492@1|root,COG5492@2|Bacteria,4NH1K@976|Bacteroidetes,1HZUI@117743|Flavobacteriia,3ZP4P@59732|Chryseobacterium	976|Bacteroidetes	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_3985123_2	583355.Caka_1736	3.522e-70	274.0	COG2312@1|root,COG2312@2|Bacteria,46TMX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
CH3_k127_3985123_0	1396141.BATP01000034_gene4198	1.055e-290	965.0	COG1409@1|root,COG2273@1|root,COG5337@1|root,COG1409@2|Bacteria,COG2273@2|Bacteria,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	3.2.1.73	ko:K01216,ko:K07004	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,CotH,DUF4971,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_43,HemolysinCabind,LTD,Laminin_G_3,Metallophos
CH3_k127_3985123_1	1232410.KI421412_gene312	9.983e-164	541.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,42MKU@68525|delta/epsilon subdivisions,2WJR3@28221|Deltaproteobacteria,43RY9@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	UvrD-like helicase C-terminal domain	rep	-	3.6.4.12	ko:K03656,ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
CH3_k127_3985123_6	1217705.F900_00640	1.197e-08	58.0	2E5S4@1|root,330GM@2|Bacteria,1NAY4@1224|Proteobacteria,1SEIX@1236|Gammaproteobacteria,3NPRS@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_3985123_4	765952.PUV_26370	1.558e-28	118.0	2E3V1@1|root,32YSA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_3985123_5	1121924.ATWH01000005_gene2605	5.532e-13	82.0	COG1874@1|root,COG1874@2|Bacteria,2H2YV@201174|Actinobacteria,4FQYV@85023|Microbacteriaceae	201174|Actinobacteria	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_3985123_3	1116472.MGMO_115c00240	2.206e-68	241.0	COG1305@1|root,COG1305@2|Bacteria	2|Bacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
CH3_k127_4013361_2	1396141.BATP01000045_gene1848	2.353e-10	68.0	COG2911@1|root,COG3866@1|root,COG4932@1|root,COG5267@1|root,COG2911@2|Bacteria,COG3866@2|Bacteria,COG4932@2|Bacteria,COG5267@2|Bacteria,46TJE@74201|Verrucomicrobia,2IVHT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
CH3_k127_4013361_0	314230.DSM3645_10162	2.041e-87	298.0	COG0524@1|root,COG0524@2|Bacteria,2IXGC@203682|Planctomycetes	203682|Planctomycetes	H	PFAM PfkB	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
CH3_k127_4013361_1	1121456.ATVA01000014_gene568	4.996e-45	175.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,42M28@68525|delta/epsilon subdivisions,2WJPF@28221|Deltaproteobacteria,2M9FY@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
CH3_k127_4025253_5	395493.BegalDRAFT_0832	3.928e-24	104.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,1RYBQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain)	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
CH3_k127_4025253_4	1121033.AUCF01000020_gene699	9.132e-39	154.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	yqfZ	-	-	-	-	-	-	-	-	-	-	-	LysM
CH3_k127_4025253_2	452637.Oter_3080	1.445e-68	244.0	2CIBN@1|root,2Z8JT@2|Bacteria	2|Bacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
CH3_k127_4025253_7	1254432.SCE1572_38305	2.165e-17	91.0	COG0631@1|root,COG0664@1|root,COG0631@2|Bacteria,COG0664@2|Bacteria,1R7UF@1224|Proteobacteria,42WUQ@68525|delta/epsilon subdivisions,2XA41@28221|Deltaproteobacteria,2YTYP@29|Myxococcales	28221|Deltaproteobacteria	T	SMART protein phosphatase 2C domain protein	pp2c12	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2,cNMP_binding
CH3_k127_4025253_0	395493.BegalDRAFT_2362	8.535e-128	430.0	COG2831@1|root,COG2831@2|Bacteria,1MWEC@1224|Proteobacteria,1RYVX@1236|Gammaproteobacteria,461AE@72273|Thiotrichales	72273|Thiotrichales	U	Haemolysin secretion/activation protein ShlB/FhaC/HecB	-	-	-	-	-	-	-	-	-	-	-	-	POTRA_2,ShlB
CH3_k127_4025253_1	395493.BegalDRAFT_0706	7.709e-89	321.0	COG3210@1|root,COG3210@2|Bacteria,1QMZZ@1224|Proteobacteria,1SG2Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	TIGRFAM filamentous hemagglutinin family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Haemagg_act
CH3_k127_4025253_6	1279009.ADICEAN_00140	2.705e-21	109.0	COG3291@1|root,COG3391@1|root,COG4935@1|root,COG3291@2|Bacteria,COG3391@2|Bacteria,COG4935@2|Bacteria,4NDZC@976|Bacteroidetes,47SFQ@768503|Cytophagia	976|Bacteroidetes	O	HYR domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Gly_rich,HYR,Laminin_G_3,PKD,SprB
CH3_k127_4025253_3	98439.AJLL01000035_gene2609	4.786e-54	205.0	COG0793@1|root,COG0793@2|Bacteria,1G30Q@1117|Cyanobacteria,1JJ6B@1189|Stigonemataceae	1117|Cyanobacteria	M	Tricorn protease C1 domain	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41,Tricorn_C1
CH3_k127_4043747_3	378806.STAUR_7504	8.785e-161	544.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,1QUYA@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
CH3_k127_4043747_9	497964.CfE428DRAFT_5731	7.579e-64	225.0	COG2197@1|root,COG2197@2|Bacteria,46UBU@74201|Verrucomicrobia	74201|Verrucomicrobia	T	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CH3_k127_4043747_1	452637.Oter_0871	1.458e-203	658.0	COG0370@1|root,COG0370@2|Bacteria,46SH4@74201|Verrucomicrobia,3K85F@414999|Opitutae	414999|Opitutae	P	transporter of a GTP-driven Fe(2 ) uptake system	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
CH3_k127_4043747_14	497964.CfE428DRAFT_6371	5.824e-17	83.0	COG1918@1|root,COG1918@2|Bacteria	2|Bacteria	P	iron ion homeostasis	feoA	GO:0000041,GO:0006810,GO:0006811,GO:0006812,GO:0006826,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0015684,GO:0030001,GO:0033554,GO:0034220,GO:0034755,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070627,GO:0070838,GO:0072511,GO:0097286,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098707,GO:0098711,GO:0098739,GO:0099587,GO:1903874	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
CH3_k127_4043747_21	452637.Oter_0873	6.772e-06	52.0	COG1918@1|root,COG1918@2|Bacteria	2|Bacteria	P	iron ion homeostasis	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
CH3_k127_4043747_20	608538.HTH_0820	6.1e-08	58.0	COG0268@1|root,COG0268@2|Bacteria,2G49M@200783|Aquificae	200783|Aquificae	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
CH3_k127_4043747_11	88036.EFJ24329	6.318e-57	206.0	COG0637@1|root,KOG2177@1|root,KOG2177@2759|Eukaryota,KOG2914@2759|Eukaryota,37MAK@33090|Viridiplantae,3GD1A@35493|Streptophyta	35493|Streptophyta	O	NHL repeat-containing protein	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009314,GO:0009416,GO:0009507,GO:0009532,GO:0009534,GO:0009536,GO:0009570,GO:0009579,GO:0009628,GO:0010196,GO:0016020,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0050896,GO:1990066	-	-	-	-	-	-	-	-	-	-	HAD_2,NHL,Thioredoxin_8
CH3_k127_4043747_12	1168034.FH5T_19355	3.787e-47	183.0	COG1387@1|root,COG1387@2|Bacteria,4NMBC@976|Bacteroidetes,2FNU7@200643|Bacteroidia	976|Bacteroidetes	E	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CH3_k127_4043747_13	1123242.JH636435_gene1168	3.952e-25	113.0	COG1413@1|root,COG1413@2|Bacteria,2J2I0@203682|Planctomycetes	203682|Planctomycetes	C	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CH3_k127_4043747_7	547042.BACCOPRO_00992	4.035e-122	420.0	COG1572@1|root,COG1572@2|Bacteria,4PJMZ@976|Bacteroidetes,2FZ9J@200643|Bacteroidia	976|Bacteroidetes	S	Domain of unknown function (DUF4091)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4091
CH3_k127_4043747_4	1499967.BAYZ01000177_gene5729	1.452e-145	464.0	COG0207@1|root,COG0207@2|Bacteria	2|Bacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
CH3_k127_4043747_15	351160.RCIX1317	9.243e-16	79.0	COG0286@1|root,arCOG02632@2157|Archaea,2XVXC@28890|Euryarchaeota,2N9DJ@224756|Methanomicrobia	224756|Methanomicrobia	V	HsdM N-terminal domain	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
CH3_k127_4043747_10	261292.Nit79A3_3402	1.134e-63	225.0	COG0637@1|root,COG0637@2|Bacteria,1PUMZ@1224|Proteobacteria,2VQN2@28216|Betaproteobacteria	28216|Betaproteobacteria	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
CH3_k127_4043747_19	1122201.AUAZ01000018_gene1698	1.096e-10	69.0	2E5B0@1|root,33033@2|Bacteria,1ND0X@1224|Proteobacteria,1SEBX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_4043747_16	96561.Dole_0867	6.194e-14	77.0	COG2204@1|root,COG3829@1|root,COG4191@1|root,COG2204@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PZ5@68525|delta/epsilon subdivisions,2WM1A@28221|Deltaproteobacteria,2MJZM@213118|Desulfobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_9,Response_reg
CH3_k127_4043747_22	1122599.AUGR01000027_gene1284	5.899e-05	57.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RYEM@1236|Gammaproteobacteria,1XHAK@135619|Oceanospirillales	135619|Oceanospirillales	T	CHASE2	-	-	-	-	-	-	-	-	-	-	-	-	CHASE2,EAL,GGDEF
CH3_k127_4043747_23	1033744.CAEL01000023_gene258	0.0007059	53.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,22H03@1570339|Peptoniphilaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,sCache_like
CH3_k127_4043747_17	1906.SFRA_03940	8.283e-14	85.0	COG0745@1|root,COG0745@2|Bacteria,2GJ2N@201174|Actinobacteria	201174|Actinobacteria	T	response regulator, receiver	kdpE	-	-	ko:K02483,ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CH3_k127_4043747_2	1121106.JQKB01000056_gene5865	2.406e-180	604.0	28MUA@1|root,2ZB28@2|Bacteria,1R8RF@1224|Proteobacteria	1224|Proteobacteria	S	Capsule biosynthesis CapC	-	-	-	ko:K22116	-	-	-	-	ko00000	-	-	-	Caps_synth_CapC
CH3_k127_4043747_18	1192034.CAP_6422	7e-13	79.0	2E205@1|root,32X8D@2|Bacteria,1N4MZ@1224|Proteobacteria,43CVC@68525|delta/epsilon subdivisions,2X83A@28221|Deltaproteobacteria,2YW05@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_4043747_0	1121106.JQKB01000056_gene5861	0.0	1147.0	COG1413@1|root,COG1413@2|Bacteria,1R5Z1@1224|Proteobacteria	1224|Proteobacteria	C	lyase activity	capB	-	-	ko:K01932	-	-	-	-	ko00000,ko01000	-	-	-	-
CH3_k127_4043747_5	411479.BACUNI_04071	9.781e-135	452.0	COG0383@1|root,COG0383@2|Bacteria,4NI6N@976|Bacteroidetes,2FQGF@200643|Bacteroidia,4ANYA@815|Bacteroidaceae	976|Bacteroidetes	G	COG COG0383 Alpha-mannosidase	-	-	-	-	-	-	-	-	-	-	-	-	CBM-like,Glyco_hydro_38,Glyco_hydro_38C
CH3_k127_4051852_4	497964.CfE428DRAFT_5712	1.435e-47	175.0	COG1520@1|root,COG1520@2|Bacteria,46THI@74201|Verrucomicrobia	2|Bacteria	S	SMART Pyrrolo-quinoline quinone	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CH3_k127_4051852_0	595460.RRSWK_06189	2.238e-261	831.0	COG1894@1|root,COG1894@2|Bacteria,2IXJ8@203682|Planctomycetes	203682|Planctomycetes	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	1.17.1.9	ko:K00122	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
CH3_k127_4051852_2	595460.RRSWK_05849	4.894e-138	456.0	COG0493@1|root,COG3383@1|root,COG0493@2|Bacteria,COG3383@2|Bacteria,2J2W6@203682|Planctomycetes	203682|Planctomycetes	E	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_4,Fer4_20,Pyr_redox_2
CH3_k127_4051852_5	448385.sce0162	1.902e-47	182.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,42TDG@68525|delta/epsilon subdivisions,2WPJP@28221|Deltaproteobacteria,2Z1CP@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
CH3_k127_4051852_1	886293.Sinac_0942	5.856e-224	704.0	COG3119@1|root,COG3119@2|Bacteria,2IX9T@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CH3_k127_4051852_3	521674.Plim_0129	2.838e-109	380.0	COG0551@1|root,COG2010@1|root,COG0551@2|Bacteria,COG2010@2|Bacteria,2IY3X@203682|Planctomycetes	203682|Planctomycetes	CL	Protein of unknown function (DUF1587)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt3,PSD2,PSD3,PSD4,PSD5
CH3_k127_4078113_5	76869.PputGB1_2810	0.0004205	51.0	COG4447@1|root,COG4447@2|Bacteria,1R84R@1224|Proteobacteria,1SZVU@1236|Gammaproteobacteria,1YZN5@136845|Pseudomonas putida group	1236|Gammaproteobacteria	S	Photosynthesis system II assembly factor YCF48	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
CH3_k127_4078113_3	382464.ABSI01000011_gene2595	1.91e-51	201.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	phoQ	-	2.7.13.3	ko:K07637,ko:K07638,ko:K07717	ko01503,ko02020,ko02026,map01503,map02020,map02026	M00444,M00445,M00518,M00709,M00721,M00723,M00724,M00742,M00743,M00744	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	HAMP,HATPase_c,HATPase_c_3,HisKA
CH3_k127_4078113_2	1125863.JAFN01000001_gene1060	2.131e-96	337.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKFA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
CH3_k127_4078113_4	243090.RB4127	5.351e-45	175.0	COG3568@1|root,COG3568@2|Bacteria,2IZ9W@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CH3_k127_4078113_0	497964.CfE428DRAFT_4279	1.15e-161	521.0	COG0773@1|root,COG0773@2|Bacteria,46THM@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Mur ligase middle domain protein	-	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CH3_k127_4078113_1	903818.KI912268_gene1381	4.224e-145	476.0	COG3863@1|root,COG3863@2|Bacteria	2|Bacteria	T	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C92
CH3_k127_4099246_4	1267535.KB906767_gene5108	1.978e-95	332.0	COG0577@1|root,COG0577@2|Bacteria,3Y31H@57723|Acidobacteria,2JITF@204432|Acidobacteriia	204432|Acidobacteriia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
CH3_k127_4099246_0	452637.Oter_1883	4.893e-311	972.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
CH3_k127_4099246_3	1492737.FEM08_16420	1.029e-223	725.0	COG0383@1|root,COG0383@2|Bacteria	2|Bacteria	G	mannose metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-mann_mid,DUF5054,Glyco_hydro_38,Glyco_hydro_38C
CH3_k127_4099246_2	1235803.C825_03120	1.019e-231	741.0	COG1331@1|root,COG1331@2|Bacteria,4NIS8@976|Bacteroidetes,2FRC4@200643|Bacteroidia	976|Bacteroidetes	O	Highly conserved protein containing a thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_4099246_1	509635.N824_01000	1.961e-232	749.0	COG0383@1|root,COG0383@2|Bacteria	2|Bacteria	G	mannose metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-mann_mid,DUF5054,Glyco_hydro_38,Glyco_hydro_38C
CH3_k127_4099246_5	452637.Oter_1883	4.418e-16	81.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
CH3_k127_4104907_2	384765.SIAM614_29666	5.118e-32	134.0	COG1082@1|root,COG1082@2|Bacteria,1MWJ3@1224|Proteobacteria,2TR21@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	sugar phosphate	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CH3_k127_4104907_1	497964.CfE428DRAFT_3429	9.569e-71	261.0	COG0542@1|root,COG0542@2|Bacteria,46SD6@74201|Verrucomicrobia	74201|Verrucomicrobia	O	AAA ATPase central domain protein	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
CH3_k127_4104907_0	1123242.JH636435_gene2138	3.682e-95	334.0	COG0673@1|root,COG0673@2|Bacteria,2IX05@203682|Planctomycetes	203682|Planctomycetes	S	NADH-dependent dyhydrogenase related protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CH3_k127_4117136_12	1123503.KB908056_gene2238	7.875e-27	123.0	COG5340@1|root,COG5340@2|Bacteria,1R80Q@1224|Proteobacteria,2U4TW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	AbiEi antitoxin C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_1,AbiEi_4
CH3_k127_4117136_2	1382359.JIAL01000001_gene1690	9.477e-177	575.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,3Y3ZP@57723|Acidobacteria,2JI7Y@204432|Acidobacteriia	204432|Acidobacteriia	EU	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
CH3_k127_4117136_10	1121904.ARBP01000010_gene2339	8.269e-31	122.0	COG3369@1|root,COG3369@2|Bacteria,4NW9E@976|Bacteroidetes,47W0Y@768503|Cytophagia	976|Bacteroidetes	S	Iron-binding zinc finger CDGSH type	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
CH3_k127_4117136_9	1121440.AUMA01000016_gene183	7.1e-33	129.0	COG3549@1|root,COG3549@2|Bacteria,1MZKX@1224|Proteobacteria,42VG7@68525|delta/epsilon subdivisions,2WP7R@28221|Deltaproteobacteria,2MDD2@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Plasmid maintenance system killer	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
CH3_k127_4117136_11	926569.ANT_30650	1.647e-30	123.0	COG3093@1|root,COG3093@2|Bacteria	2|Bacteria	K	addiction module antidote protein HigA	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3,HTH_31
CH3_k127_4117136_0	314230.DSM3645_24165	6.571e-192	610.0	COG0591@1|root,COG0591@2|Bacteria,2IWSN@203682|Planctomycetes	203682|Planctomycetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
CH3_k127_4117136_8	180332.JTGN01000016_gene1024	2.965e-33	143.0	COG0407@1|root,COG0407@2|Bacteria	2|Bacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
CH3_k127_4117136_15	697281.Mahau_2672	1.149e-08	67.0	COG0407@1|root,COG0407@2|Bacteria,1VJHK@1239|Firmicutes,24TV3@186801|Clostridia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
CH3_k127_4117136_7	761193.Runsl_2772	6.541e-50	190.0	COG0329@1|root,COG0329@2|Bacteria,4NI1I@976|Bacteroidetes,47NMJ@768503|Cytophagia	976|Bacteroidetes	EM	Dihydrodipicolinate synthetase family	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
CH3_k127_4117136_5	234267.Acid_5864	1.314e-53	201.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CH3_k127_4117136_1	452637.Oter_2196	7.211e-186	593.0	COG0673@1|root,COG0673@2|Bacteria,46U95@74201|Verrucomicrobia,3K969@414999|Opitutae	414999|Opitutae	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CH3_k127_4117136_3	1267535.KB906767_gene3674	1.644e-130	425.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	MA20_02630	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CH3_k127_4117136_4	555079.Toce_1809	4.526e-54	202.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia,42FIY@68295|Thermoanaerobacterales	186801|Clostridia	G	PFAM ROK family protein	glcK	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10220	ROK
CH3_k127_4117136_13	1096546.WYO_0029	2.235e-12	74.0	COG3437@1|root,COG4191@1|root,COG3437@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,1JRB9@119045|Methylobacteriaceae	28211|Alphaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
CH3_k127_4117136_14	743719.PaelaDRAFT_1789	2.555e-10	72.0	COG2207@1|root,COG2207@2|Bacteria,1UMYK@1239|Firmicutes,4IU3F@91061|Bacilli,277HV@186822|Paenibacillaceae	91061|Bacilli	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
CH3_k127_4117136_6	497964.CfE428DRAFT_2773	2.154e-51	199.0	2F6K4@1|root,33Z30@2|Bacteria,46VYC@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Putative beta-barrel porin 2	-	-	-	-	-	-	-	-	-	-	-	-	BBP2_2
CH3_k127_4121489_9	1238182.C882_1167	2.417e-44	168.0	COG0204@1|root,COG0204@2|Bacteria,1R787@1224|Proteobacteria,2U4Y1@28211|Alphaproteobacteria,2JW4V@204441|Rhodospirillales	204441|Rhodospirillales	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
CH3_k127_4121489_0	1123242.JH636435_gene793	7.666e-187	596.0	COG0415@1|root,COG0415@2|Bacteria,2IZKY@203682|Planctomycetes	203682|Planctomycetes	L	FAD binding domain of DNA photolyase	-	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
CH3_k127_4121489_1	1499967.BAYZ01000171_gene5584	4.285e-125	410.0	COG0407@1|root,COG0407@2|Bacteria,2NRD5@2323|unclassified Bacteria	2|Bacteria	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
CH3_k127_4121489_4	1300345.LF41_1322	1.114e-99	337.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,1S5WE@1236|Gammaproteobacteria,1X3ZI@135614|Xanthomonadales	135614|Xanthomonadales	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CH3_k127_4121489_8	497964.CfE428DRAFT_2483	6.467e-66	235.0	COG0697@1|root,COG0697@2|Bacteria,46SR7@74201|Verrucomicrobia	74201|Verrucomicrobia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CH3_k127_4121489_7	497964.CfE428DRAFT_1729	8.788e-72	248.0	COG0122@1|root,COG0122@2|Bacteria,46V2J@74201|Verrucomicrobia	74201|Verrucomicrobia	L	endonuclease III	-	-	-	-	-	-	-	-	-	-	-	-	HhH-GPD
CH3_k127_4121489_10	583355.Caka_1102	2.309e-37	149.0	COG0681@1|root,COG0681@2|Bacteria	2|Bacteria	U	signal peptide processing	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
CH3_k127_4121489_5	497964.CfE428DRAFT_3666	4.147e-92	311.0	COG1409@1|root,COG1409@2|Bacteria,46TUP@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
CH3_k127_4121489_6	192952.MM_1779	3.31e-73	252.0	COG1926@1|root,arCOG06847@2157|Archaea,2XWRW@28890|Euryarchaeota,2NABG@224756|Methanomicrobia	224756|Methanomicrobia	S	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH
CH3_k127_4121489_3	555779.Dthio_PD2105	4.368e-117	384.0	COG3677@1|root,COG3677@2|Bacteria,1MXYX@1224|Proteobacteria,43B03@68525|delta/epsilon subdivisions,2X6E6@28221|Deltaproteobacteria,2MH1Y@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	Transposase zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
CH3_k127_4121489_2	999419.HMPREF1077_00773	6.785e-125	413.0	COG0673@1|root,COG0673@2|Bacteria,4NGGS@976|Bacteroidetes,2FTQH@200643|Bacteroidia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CH3_k127_4121489_16	767817.Desgi_1747	0.0001278	45.0	COG0399@1|root,COG0399@2|Bacteria	2|Bacteria	E	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1,Y2_Tnp,Zn_Tnp_IS91
CH3_k127_4121489_13	177437.HRM2_06590	2.11e-14	79.0	COG0399@1|root,COG0399@2|Bacteria,1PRVB@1224|Proteobacteria,431RA@68525|delta/epsilon subdivisions,2X518@28221|Deltaproteobacteria,2MP3U@213118|Desulfobacterales	28221|Deltaproteobacteria	M	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp
CH3_k127_4121489_12	27923.ML204429a-PA	1.357e-17	99.0	2CMMP@1|root,2QQVA@2759|Eukaryota,38DQG@33154|Opisthokonta,3BC84@33208|Metazoa	33208|Metazoa	S	F5/8 type C domain	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C
CH3_k127_4121489_11	1396141.BATP01000028_gene2285	2.047e-24	121.0	COG4412@1|root,COG5306@1|root,COG4412@2|Bacteria,COG5306@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	ko:K07004,ko:K09955,ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	Big_4,F5_F8_type_C,Laminin_G_3
CH3_k127_4121489_14	1122609.AUGT01000002_gene3860	1.262e-08	69.0	COG3227@1|root,COG4412@1|root,COG3227@2|Bacteria,COG4412@2|Bacteria,2GJEW@201174|Actinobacteria,4DPZQ@85009|Propionibacteriales	201174|Actinobacteria	E	Fungalysin/Thermolysin Propeptide Motif	-	-	-	-	-	-	-	-	-	-	-	-	FTP,PA,Peptidase_M4,Peptidase_M4_C
CH3_k127_4125518_0	945713.IALB_0720	2.385e-204	668.0	COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria	2|Bacteria	P	mercury ion transmembrane transporter activity	fixI	GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
CH3_k127_4125518_1	575540.Isop_0386	2.429e-87	297.0	COG1874@1|root,COG1874@2|Bacteria,2J0Y5@203682|Planctomycetes	203682|Planctomycetes	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4832
CH3_k127_4128480_9	926566.Terro_0347	2.055e-15	78.0	COG1233@1|root,COG1233@2|Bacteria,3Y3I8@57723|Acidobacteria,2JI78@204432|Acidobacteriia	204432|Acidobacteriia	C	TIGRFAM phytoene desaturase	-	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
CH3_k127_4128480_2	44251.PDUR_01820	4.789e-148	482.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4HB97@91061|Bacilli,26T63@186822|Paenibacillaceae	91061|Bacilli	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CH3_k127_4128480_11	506534.Rhein_0083	2.811e-07	61.0	COG0457@1|root,COG0457@2|Bacteria,1RKT6@1224|Proteobacteria,1S7R3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PFAM TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_4128480_0	1396141.BATP01000003_gene5043	5.198e-237	741.0	COG1233@1|root,COG1233@2|Bacteria,46SE8@74201|Verrucomicrobia,2IVA7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
CH3_k127_4128480_10	1158292.JPOE01000002_gene3555	6.638e-12	69.0	COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria,2VHIR@28216|Betaproteobacteria,1KMXP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	Subunit R is required for both nuclease and ATPase activities, but not for modification	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
CH3_k127_4128480_5	240016.ABIZ01000001_gene1135	7.852e-41	155.0	COG1943@1|root,COG1943@2|Bacteria,46W84@74201|Verrucomicrobia,2IVXZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
CH3_k127_4128480_8	682795.AciX8_1298	1.726e-17	86.0	COG1943@1|root,COG1943@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
CH3_k127_4128480_3	1396141.BATP01000003_gene5044	1.574e-94	321.0	COG1215@1|root,COG1215@2|Bacteria,46WX3@74201|Verrucomicrobia,2IVN1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CH3_k127_4128480_6	639030.JHVA01000001_gene3731	5.322e-35	141.0	2E9V0@1|root,3340V@2|Bacteria	2|Bacteria	S	carotenoid biosynthetic process	crtO	-	-	ko:K10212	ko00906,map00906	-	R07656	RC00041	ko00000,ko00001,ko01000	-	-	-	-
CH3_k127_4128480_4	204669.Acid345_2517	6.552e-72	251.0	COG3809@1|root,COG3809@2|Bacteria,3Y803@57723|Acidobacteria	57723|Acidobacteria	S	Transcription factor zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	DZR,zf-TFIIB
CH3_k127_4128480_1	452637.Oter_1792	1.862e-172	556.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CH3_k127_4128480_7	497964.CfE428DRAFT_5469	1.147e-32	132.0	COG2067@1|root,COG2067@2|Bacteria,46SR3@74201|Verrucomicrobia	74201|Verrucomicrobia	I	PFAM membrane protein involved in aromatic hydrocarbon degradation	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
CH3_k127_4128609_1	1396418.BATQ01000160_gene4912	1.536e-29	124.0	COG3547@1|root,COG3547@2|Bacteria,46WNP@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Transposase (IS116 IS110 IS902 family)	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
CH3_k127_4128609_2	1396418.BATQ01000160_gene4912	3.634e-29	124.0	COG3547@1|root,COG3547@2|Bacteria,46WNP@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Transposase (IS116 IS110 IS902 family)	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
CH3_k127_4128609_4	1121373.KB903654_gene1652	5.125e-05	57.0	COG1208@1|root,COG1208@2|Bacteria	2|Bacteria	JM	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon	ydcK	-	5.4.2.9	ko:K01841	ko00440,ko01100,ko01120,ko01130,map00440,map01100,map01120,map01130	-	R00661	RC02792	ko00000,ko00001,ko01000	-	-	-	CBM_35,NTP_transf_3,PEP_mutase
CH3_k127_4128609_0	1123399.AQVE01000001_gene684	2.462e-111	396.0	COG3291@1|root,COG5295@1|root,COG3291@2|Bacteria,COG5295@2|Bacteria,1RGWM@1224|Proteobacteria,1SKIX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	UW	Metallo-peptidase family M12B Reprolysin-like	-	-	-	-	-	-	-	-	-	-	-	-	Reprolysin_3
CH3_k127_4128609_3	278957.ABEA03000004_gene4536	1.507e-16	89.0	COG2165@1|root,COG2165@2|Bacteria,46YQC@74201|Verrucomicrobia,3K9ZW@414999|Opitutae	414999|Opitutae	U	N-terminal cleavage protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
CH3_k127_4143287_2	1267535.KB906767_gene4768	3.362e-18	89.0	2DBP2@1|root,2ZA71@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_4143287_0	1198452.Jab_2c25040	8.014e-128	419.0	COG0657@1|root,COG0657@2|Bacteria,1N5QB@1224|Proteobacteria,2VPXR@28216|Betaproteobacteria,474PV@75682|Oxalobacteraceae	28216|Betaproteobacteria	I	alpha/beta hydrolase fold	xynB	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
CH3_k127_4143287_1	118173.KB235914_gene3829	1.657e-122	411.0	2DBP2@1|root,2ZA71@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_4143674_21	452637.Oter_1438	4.183e-92	304.0	COG0861@1|root,COG0861@2|Bacteria,46TS9@74201|Verrucomicrobia,3K8X2@414999|Opitutae	414999|Opitutae	P	membrane	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
CH3_k127_4143674_31	386456.JQKN01000006_gene1261	6.002e-58	214.0	COG3177@1|root,arCOG03110@2157|Archaea,2XUN8@28890|Euryarchaeota,23PGE@183925|Methanobacteria	183925|Methanobacteria	K	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,HTH_24
CH3_k127_4143674_46	930171.Asphe3_35720	2.379e-14	76.0	COG0347@1|root,COG0347@2|Bacteria,2H6FT@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the P(II) protein family	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_4143674_16	1122221.JHVI01000015_gene1707	4.611e-104	349.0	COG3329@1|root,COG3329@2|Bacteria,1WJER@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Na+-dependent bicarbonate transporter superfamily	-	-	-	ko:K07086	-	-	-	-	ko00000	-	-	-	Sbt_1
CH3_k127_4143674_28	1128421.JAGA01000001_gene2371	5.336e-66	229.0	COG0041@1|root,COG0041@2|Bacteria,2NPN4@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	GO:0008150,GO:0040007	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.purE,iNJ661.Rv3275c	AIRC
CH3_k127_4143674_11	1521187.JPIM01000035_gene3407	6.259e-126	417.0	COG0026@1|root,COG0026@2|Bacteria,2G5PV@200795|Chloroflexi,375PJ@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
CH3_k127_4143674_18	314230.DSM3645_18936	1.419e-100	349.0	COG0591@1|root,COG0591@2|Bacteria,2IY5N@203682|Planctomycetes	203682|Planctomycetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
CH3_k127_4143674_49	314230.DSM3645_18931	8.488e-08	60.0	2EJH6@1|root,33D83@2|Bacteria,2J1HK@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF3311)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3311
CH3_k127_4143674_41	1403819.BATR01000120_gene4247	1.587e-37	152.0	COG3932@1|root,COG3932@2|Bacteria,46T8A@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Exopolysaccharide synthesis, ExoD	-	-	-	-	-	-	-	-	-	-	-	-	ExoD
CH3_k127_4143674_42	240016.ABIZ01000001_gene760	1.071e-30	136.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIAA-like,Usp
CH3_k127_4143674_44	1089550.ATTH01000001_gene756	3.19e-22	108.0	COG0589@1|root,COG0589@2|Bacteria,4PICI@976|Bacteroidetes,1FK3M@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CH3_k127_4143674_45	452637.Oter_1439	5.536e-21	98.0	COG1544@1|root,COG1544@2|Bacteria,46WN8@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Sigma 54 modulation protein / S30EA ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_S30AE
CH3_k127_4143674_25	1403819.BATR01000124_gene4434	1.502e-84	297.0	COG2738@1|root,COG2738@2|Bacteria,46TH9@74201|Verrucomicrobia,2IUJW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Putative neutral zinc metallopeptidase	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
CH3_k127_4143674_12	452637.Oter_1440	3.09e-121	395.0	COG0583@1|root,COG0583@2|Bacteria,46TZU@74201|Verrucomicrobia	74201|Verrucomicrobia	K	LysR substrate binding domain	-	-	-	ko:K03717	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
CH3_k127_4143674_36	452637.Oter_1109	7.101e-47	179.0	COG4276@1|root,COG4276@2|Bacteria,46X6Q@74201|Verrucomicrobia,3K9Y1@414999|Opitutae	414999|Opitutae	S	Pfam Polyketide cyclase dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_4143674_37	595460.RRSWK_06787	4.093e-43	164.0	COG3449@1|root,COG3449@2|Bacteria,2J2ST@203682|Planctomycetes	203682|Planctomycetes	L	SOUL heme-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SOUL
CH3_k127_4143674_2	530564.Psta_0993	2.404e-268	837.0	COG1574@1|root,COG1574@2|Bacteria,2IX0K@203682|Planctomycetes	203682|Planctomycetes	S	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
CH3_k127_4143674_10	748247.AZKH_2522	5.709e-129	413.0	COG1335@1|root,COG1335@2|Bacteria,1MU5N@1224|Proteobacteria,2VJFI@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	isochorismatase hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
CH3_k127_4143674_26	1403819.BATR01000182_gene6271	4.95e-74	255.0	COG0778@1|root,COG0778@2|Bacteria,46V9P@74201|Verrucomicrobia,2IU8H@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Nitroreductase family	-	-	1.5.1.34	ko:K10679	ko00633,ko01120,map00633,map01120	-	R08014,R08017,R08042	RC00250	ko00000,ko00001,ko01000	-	-	-	Nitroreductase
CH3_k127_4143674_19	1403819.BATR01000053_gene1630	1.424e-100	332.0	COG1741@1|root,COG1741@2|Bacteria,46SRJ@74201|Verrucomicrobia,2IU6M@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Pirin	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
CH3_k127_4143674_27	1396141.BATP01000025_gene912	1.84e-67	240.0	COG0583@1|root,COG0583@2|Bacteria,46ZKT@74201|Verrucomicrobia,2IVKZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CH3_k127_4143674_23	522306.CAP2UW1_1318	1.667e-87	299.0	COG3597@1|root,COG3597@2|Bacteria,1QG9J@1224|Proteobacteria,2VIRR@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Tellurite resistance protein TerB	-	-	-	-	-	-	-	-	-	-	-	-	DUF533,TerB
CH3_k127_4143674_13	671143.DAMO_0966	1.003e-119	400.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2NPE1@2323|unclassified Bacteria	2|Bacteria	S	Peptidase family M50	spoIVFB	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K06212,ko:K06402	-	-	-	-	ko00000,ko01000,ko01002,ko02000	1.A.16.1.1,1.A.16.1.3	-	-	CBS,Form_Nir_trans,Peptidase_M50
CH3_k127_4143674_43	452637.Oter_1439	4.14e-26	113.0	COG1544@1|root,COG1544@2|Bacteria,46WN8@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Sigma 54 modulation protein / S30EA ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_S30AE
CH3_k127_4143674_22	1403819.BATR01000124_gene4434	2.051e-88	300.0	COG2738@1|root,COG2738@2|Bacteria,46TH9@74201|Verrucomicrobia,2IUJW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Putative neutral zinc metallopeptidase	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
CH3_k127_4143674_29	1396141.BATP01000047_gene3930	1.004e-65	228.0	COG3476@1|root,COG3476@2|Bacteria,46SXT@74201|Verrucomicrobia,2IVZD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	TspO/MBR family	-	-	-	-	-	-	-	-	-	-	-	-	TspO_MBR
CH3_k127_4143674_40	472759.Nhal_2122	1.105e-41	160.0	COG0702@1|root,COG0702@2|Bacteria,1QV7M@1224|Proteobacteria,1T2N4@1236|Gammaproteobacteria,1WYK0@135613|Chromatiales	135613|Chromatiales	GM	intermediate-associated protein 30	-	-	-	-	-	-	-	-	-	-	-	-	CIA30
CH3_k127_4143674_20	926569.ANT_25430	1.239e-94	326.0	COG2335@1|root,COG2335@2|Bacteria,2G7AJ@200795|Chloroflexi	200795|Chloroflexi	M	Four repeated domains in the Fasciclin I family of proteins, present in many other contexts.	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
CH3_k127_4143674_35	1125863.JAFN01000001_gene83	4.272e-50	186.0	COG2020@1|root,COG2020@2|Bacteria,1RBUU@1224|Proteobacteria,42UT0@68525|delta/epsilon subdivisions,2WQKM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
CH3_k127_4143674_48	452637.Oter_1440	3.565e-08	57.0	COG0583@1|root,COG0583@2|Bacteria,46TZU@74201|Verrucomicrobia	74201|Verrucomicrobia	K	LysR substrate binding domain	-	-	-	ko:K03717	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
CH3_k127_4143674_34	926566.Terro_3682	3.094e-51	190.0	COG2152@1|root,COG2152@2|Bacteria,3Y5H3@57723|Acidobacteria,2JM4K@204432|Acidobacteriia	204432|Acidobacteriia	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CH3_k127_4143674_4	497964.CfE428DRAFT_2154	3.517e-192	635.0	COG1674@1|root,COG1674@2|Bacteria,46SCV@74201|Verrucomicrobia	74201|Verrucomicrobia	D	PFAM cell divisionFtsK SpoIIIE	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
CH3_k127_4143674_30	99598.Cal7507_3402	2.423e-62	222.0	2EY4W@1|root,33RDQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_4143674_9	99598.Cal7507_3403	4.269e-131	433.0	COG0754@1|root,COG0754@2|Bacteria	2|Bacteria	E	glutathionylspermidine amidase activity	gsp	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008884,GO:0008885,GO:0016787,GO:0016810,GO:0016811,GO:0016874,GO:0016879,GO:0016880,GO:0044424,GO:0044444,GO:0044464	3.5.1.78,6.3.1.8	ko:K01460	ko00480,ko01100,map00480,map01100	-	R01917,R01918	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	iECIAI39_1322.ECIAI39_3484	CHAP,GSP_synth
CH3_k127_4143674_32	99598.Cal7507_3404	7.104e-52	193.0	2F1DQ@1|root,33UEG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_4143674_39	1232410.KI421424_gene1610	4.592e-42	175.0	COG1295@1|root,COG1295@2|Bacteria,1QICW@1224|Proteobacteria,42MBW@68525|delta/epsilon subdivisions,2WK2Z@28221|Deltaproteobacteria,43SWT@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	PFAM ribonuclease BN	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Rrf2,Virul_fac_BrkB
CH3_k127_4143674_5	240016.ABIZ01000001_gene5947	1.701e-179	569.0	COG0686@1|root,COG0686@2|Bacteria,46S7U@74201|Verrucomicrobia,2ITXS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Alanine dehydrogenase/PNT, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
CH3_k127_4143674_8	1122947.FR7_4282	1.637e-157	511.0	COG2271@1|root,COG2271@2|Bacteria,1TS33@1239|Firmicutes,4H38R@909932|Negativicutes	909932|Negativicutes	G	Major Facilitator	-	-	-	ko:K07783	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.1.4.4,2.A.1.4.6	-	-	MFS_1
CH3_k127_4143674_6	1210884.HG799463_gene9560	1.141e-176	568.0	COG0578@1|root,COG0578@2|Bacteria,2IX2V@203682|Planctomycetes	203682|Planctomycetes	C	Glycerol-3-phosphate dehydrogenase	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
CH3_k127_4143674_17	679935.Alfi_2300	1.476e-103	344.0	COG0647@1|root,COG0647@2|Bacteria,4NG49@976|Bacteroidetes,2FRNM@200643|Bacteroidia	976|Bacteroidetes	G	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K02566	-	-	-	-	ko00000	-	-	-	Hydrolase_6,Hydrolase_like
CH3_k127_4143674_0	497964.CfE428DRAFT_0238	0.0	1265.0	COG2010@1|root,COG2010@2|Bacteria,46TSG@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
CH3_k127_4143674_3	886293.Sinac_7008	2.052e-252	784.0	COG4102@1|root,COG4102@2|Bacteria,2IX5T@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CH3_k127_4143674_15	234267.Acid_7032	3.285e-105	356.0	COG2271@1|root,COG2271@2|Bacteria,3Y3FW@57723|Acidobacteria	57723|Acidobacteria	G	Organic Anion Transporter Polypeptide (OATP) family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CH3_k127_4143674_1	1403819.BATR01000135_gene4816	0.0	1025.0	COG4692@1|root,COG4692@2|Bacteria,46SE5@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2,VCBS
CH3_k127_4143674_24	1121430.JMLG01000019_gene1656	1.103e-84	297.0	COG1322@1|root,COG1322@2|Bacteria,1TPWI@1239|Firmicutes,24CA4@186801|Clostridia,260IP@186807|Peptococcaceae	186801|Clostridia	S	RmuC family	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
CH3_k127_4143674_33	497964.CfE428DRAFT_0998	7.179e-52	192.0	COG0350@1|root,COG0350@2|Bacteria	2|Bacteria	L	methylated-DNA-[protein]-cysteine S-methyltransferase activity	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
CH3_k127_4143674_38	497964.CfE428DRAFT_1520	5.63e-43	160.0	COG0251@1|root,COG0251@2|Bacteria,46T40@74201|Verrucomicrobia	74201|Verrucomicrobia	J	endoribonuclease L-PSP	-	-	3.5.3.18	ko:K01482	-	-	-	-	ko00000,ko01000,ko04147	-	-	-	Ribonuc_L-PSP
CH3_k127_4143674_14	1121875.KB907547_gene3471	6.071e-117	393.0	2C20F@1|root,32R9J@2|Bacteria,4P0SP@976|Bacteroidetes	976|Bacteroidetes	S	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C92
CH3_k127_4143674_7	278957.ABEA03000215_gene4275	4.354e-158	512.0	COG0165@1|root,COG0165@2|Bacteria,46UYU@74201|Verrucomicrobia,3K76F@414999|Opitutae	414999|Opitutae	E	Argininosuccinate lyase C-terminal	-	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
CH3_k127_4158023_9	926550.CLDAP_16340	8.817e-26	109.0	COG1011@1|root,COG1011@2|Bacteria	2|Bacteria	S	phosphatase activity	-	-	3.1.3.10	ko:K07025,ko:K20866	ko00010,ko01120,map00010,map01120	-	R00947	RC00078	ko00000,ko00001,ko01000	-	-	-	HAD_2,Hydrolase,Hydrolase_like
CH3_k127_4158023_4	1122135.KB893134_gene3933	2.487e-95	320.0	COG0518@1|root,COG0518@2|Bacteria,1Q2PQ@1224|Proteobacteria,2U196@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	glutamine amidotransferase	-	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
CH3_k127_4158023_12	278957.ABEA03000195_gene491	1.762e-12	70.0	28X6Y@1|root,2ZJ59@2|Bacteria,46WIZ@74201|Verrucomicrobia,3K8DC@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_4158023_11	382464.ABSI01000005_gene1185	1.138e-16	85.0	COG5010@1|root,COG5010@2|Bacteria	2|Bacteria	-	-	tadD	-	-	ko:K20543	-	-	-	-	ko00000,ko02000	1.B.55.3	-	-	BCSC_C,SPOR,TPR_16,TPR_19,TPR_8
CH3_k127_4158023_6	497964.CfE428DRAFT_4443	6.64e-44	173.0	COG0561@1|root,COG0561@2|Bacteria,46SWT@74201|Verrucomicrobia	74201|Verrucomicrobia	S	haloacid dehalogenase-like hydrolase	cof	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
CH3_k127_4158023_0	497964.CfE428DRAFT_4284	3.198e-259	812.0	COG0674@1|root,COG0674@2|Bacteria,46SM9@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
CH3_k127_4158023_2	497964.CfE428DRAFT_4282	3.629e-151	482.0	COG1013@1|root,COG1013@2|Bacteria,46SRY@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
CH3_k127_4158023_8	269799.Gmet_2576	1.239e-30	127.0	COG5319@1|root,COG5319@2|Bacteria,1RKDX@1224|Proteobacteria,42SDV@68525|delta/epsilon subdivisions,2WPXR@28221|Deltaproteobacteria,43T4D@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
CH3_k127_4158023_5	756272.Plabr_2090	5.646e-78	268.0	COG4099@1|root,COG4099@2|Bacteria,2IZGT@203682|Planctomycetes	203682|Planctomycetes	P	Phospholipase/Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	DLH,Peptidase_S9
CH3_k127_4158023_10	909663.KI867150_gene2927	2.094e-21	102.0	COG1042@1|root,COG1670@1|root,COG1042@2|Bacteria,COG1670@2|Bacteria,1MW98@1224|Proteobacteria,42KZW@68525|delta/epsilon subdivisions,2WIQB@28221|Deltaproteobacteria,2MR1B@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	CoA binding domain	acs	-	6.2.1.13	ko:K01905,ko:K09181,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
CH3_k127_4158023_3	497964.CfE428DRAFT_5019	2.612e-117	388.0	COG0077@1|root,COG0077@2|Bacteria,46U8V@74201|Verrucomicrobia	74201|Verrucomicrobia	E	amino acid-binding ACT domain protein	pheA	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
CH3_k127_4158023_7	1121324.CLIT_23c01830	1.86e-40	158.0	COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,249XB@186801|Clostridia	186801|Clostridia	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
CH3_k127_4158023_1	1210884.HG799467_gene13206	1.363e-153	494.0	COG0205@1|root,COG0205@2|Bacteria,2IXXF@203682|Planctomycetes	203682|Planctomycetes	G	Phosphofructokinase	-	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
CH3_k127_4166587_9	1380391.JIAS01000012_gene4526	2.603e-132	434.0	COG4948@1|root,COG4948@2|Bacteria,1R63G@1224|Proteobacteria,2TT3A@28211|Alphaproteobacteria,2JW8D@204441|Rhodospirillales	204441|Rhodospirillales	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
CH3_k127_4166587_8	1123242.JH636434_gene3764	1.488e-139	457.0	COG0673@1|root,COG0673@2|Bacteria,2IXJ0@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CH3_k127_4166587_13	649638.Trad_1837	1.738e-105	353.0	COG4948@1|root,COG4948@2|Bacteria,1WMNA@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	Mandelate racemase muconate lactonizing enzyme	ykfB	-	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
CH3_k127_4166587_4	452637.Oter_0816	1.193e-220	692.0	COG1350@1|root,COG1350@2|Bacteria	2|Bacteria	E	tryptophan synthase activity	trpB	-	4.2.1.20	ko:K01696,ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CH3_k127_4166587_16	1265505.ATUG01000001_gene3993	1.656e-63	229.0	COG4313@1|root,COG4313@2|Bacteria,1R6GU@1224|Proteobacteria,43BI4@68525|delta/epsilon subdivisions,2X6WJ@28221|Deltaproteobacteria,2MKN8@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Putative MetA-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
CH3_k127_4166587_6	886293.Sinac_0364	3.217e-164	532.0	COG0388@1|root,COG0388@2|Bacteria,2IXSE@203682|Planctomycetes	203682|Planctomycetes	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
CH3_k127_4166587_14	1267535.KB906767_gene1663	1.82e-88	316.0	COG4257@1|root,COG4257@2|Bacteria	2|Bacteria	V	antibiotic catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF5011,SLH
CH3_k127_4166587_10	1274374.CBLK010000061_gene596	5.208e-115	382.0	2CAEK@1|root,2ZCPG@2|Bacteria,1U07Z@1239|Firmicutes,4I9IQ@91061|Bacilli,271MJ@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_4166587_12	1123242.JH636435_gene2066	1.555e-112	390.0	COG2366@1|root,COG2366@2|Bacteria,2J08A@203682|Planctomycetes	203682|Planctomycetes	S	Penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
CH3_k127_4166587_3	497964.CfE428DRAFT_5897	5.561e-226	726.0	COG1073@1|root,COG1073@2|Bacteria,46TMQ@74201|Verrucomicrobia	74201|Verrucomicrobia	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_4166587_15	502025.Hoch_2530	8.318e-75	265.0	COG0845@1|root,COG0845@2|Bacteria,1MX0G@1224|Proteobacteria,42MPE@68525|delta/epsilon subdivisions,2X630@28221|Deltaproteobacteria,2Z38I@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
CH3_k127_4166587_0	502025.Hoch_2529	0.0	1191.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2YXGU@29|Myxococcales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
CH3_k127_4166587_1	502025.Hoch_2528	4.383e-311	988.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2YXGU@29|Myxococcales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
CH3_k127_4166587_5	452637.Oter_2196	1.919e-188	598.0	COG0673@1|root,COG0673@2|Bacteria,46U95@74201|Verrucomicrobia,3K969@414999|Opitutae	414999|Opitutae	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CH3_k127_4166587_11	504472.Slin_2839	5.567e-115	385.0	COG0673@1|root,COG0673@2|Bacteria,4NH96@976|Bacteroidetes,47M0H@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CH3_k127_4166587_2	240016.ABIZ01000001_gene281	1.084e-239	750.0	COG0160@1|root,COG0160@2|Bacteria,46UEH@74201|Verrucomicrobia,2IVU9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
CH3_k127_4166587_7	497964.CfE428DRAFT_1056	2.197e-143	467.0	COG3119@1|root,COG3119@2|Bacteria,46VGR@74201|Verrucomicrobia	74201|Verrucomicrobia	NP	Ig domain protein group 2 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Sulfatase
CH3_k127_4166587_17	452637.Oter_2422	2.472e-36	140.0	COG1595@1|root,COG1595@2|Bacteria,46VAN@74201|Verrucomicrobia	74201|Verrucomicrobia	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
CH3_k127_4166587_18	240016.ABIZ01000001_gene285	5.269e-32	126.0	COG0673@1|root,COG0673@2|Bacteria,46T68@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CH3_k127_4218078_1	269482.Bcep1808_6245	9.353e-118	386.0	COG3039@1|root,COG3039@2|Bacteria,1MVDK@1224|Proteobacteria,2VI1H@28216|Betaproteobacteria,1K3UX@119060|Burkholderiaceae	28216|Betaproteobacteria	L	PFAM transposase, IS4 family protein	-	-	-	ko:K07481	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DUF772
CH3_k127_4218078_0	794903.OPIT5_04415	3.892e-210	659.0	COG3550@1|root,COG3550@2|Bacteria,46XT4@74201|Verrucomicrobia,3K8Y8@414999|Opitutae	414999|Opitutae	S	Pfam:HipA_N	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
CH3_k127_4218078_2	794903.OPIT5_04410	4.056e-36	139.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
CH3_k127_4224309_1	1121877.JQKF01000077_gene2353	4.152e-06	55.0	2BYE9@1|root,34BTU@2|Bacteria,2H9CX@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_4224309_0	608506.COB47_1676	2.44e-09	70.0	2AE8G@1|root,3142G@2|Bacteria,1V7YJ@1239|Firmicutes,24JA4@186801|Clostridia,42IC5@68295|Thermoanaerobacterales	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
CH3_k127_4224309_2	448385.sce4371	4.089e-05	48.0	COG3744@1|root,COG3744@2|Bacteria,1RJ4K@1224|Proteobacteria	1224|Proteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
CH3_k127_4227125_9	1124982.MSI_15100	1.77e-07	58.0	COG2834@1|root,COG2834@2|Bacteria,2J5AT@203691|Spirochaetes	203691|Spirochaetes	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
CH3_k127_4227125_10	497964.CfE428DRAFT_6108	5.558e-05	55.0	2FCZ3@1|root,3451R@2|Bacteria,46WBW@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
CH3_k127_4227125_0	1403819.BATR01000057_gene1772	4.148e-251	809.0	COG3474@1|root,COG3474@2|Bacteria,46TEP@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
CH3_k127_4227125_3	521674.Plim_0111	6.966e-133	438.0	COG0673@1|root,COG0673@2|Bacteria,2IXJ0@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CH3_k127_4227125_5	314230.DSM3645_04115	1.95e-113	382.0	COG1073@1|root,COG1073@2|Bacteria,2IYBP@203682|Planctomycetes	203682|Planctomycetes	S	BAAT / Acyl-CoA thioester hydrolase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	AXE1,Peptidase_S9
CH3_k127_4227125_1	278957.ABEA03000010_gene3912	1.197e-234	741.0	COG0458@1|root,COG0458@2|Bacteria,46SBT@74201|Verrucomicrobia,3K7KM@414999|Opitutae	414999|Opitutae	F	Carbamoyl-phosphate synthetase ammonia chain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
CH3_k127_4227125_7	1298863.AUEP01000009_gene40	3.523e-14	88.0	COG0681@1|root,COG0681@2|Bacteria,2HES2@201174|Actinobacteria,4DUMF@85009|Propionibacteriales	201174|Actinobacteria	U	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,Peptidase_S24
CH3_k127_4227125_8	682795.AciX8_3725	2.344e-10	75.0	COG3250@1|root,COG3250@2|Bacteria,3Y3GV@57723|Acidobacteria,2JHVR@204432|Acidobacteriia	204432|Acidobacteriia	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4982,F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_64,Ig_3
CH3_k127_4227125_6	756272.Plabr_1895	3.909e-16	88.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
CH3_k127_4227125_2	330214.NIDE0551	8.087e-166	550.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria	2|Bacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_16,TPR_7,TPR_8
CH3_k127_4227125_4	118168.MC7420_3120	3.555e-116	395.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1G17N@1117|Cyanobacteria,1H72F@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
CH3_k127_4247892_1	497964.CfE428DRAFT_2167	4.985e-106	361.0	COG1364@1|root,COG1364@2|Bacteria,46SEP@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
CH3_k127_4247892_0	497964.CfE428DRAFT_2151	3.074e-128	418.0	COG0002@1|root,COG0002@2|Bacteria,46SA3@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
CH3_k127_4247892_4	1341157.RF007C_09585	7.408e-41	156.0	COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,24H94@186801|Clostridia,3WIS1@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
CH3_k127_4247892_3	382464.ABSI01000012_gene2250	4.804e-51	184.0	COG0102@1|root,COG0102@2|Bacteria,46VEU@74201|Verrucomicrobia,2IUBQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
CH3_k127_4247892_2	497964.CfE428DRAFT_4167	1.085e-76	263.0	COG1208@1|root,COG1208@2|Bacteria,46SP1@74201|Verrucomicrobia	74201|Verrucomicrobia	JM	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
CH3_k127_4247892_5	497964.CfE428DRAFT_5168	2.375e-06	54.0	2DUSB@1|root,33S06@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_4273488_2	909663.KI867150_gene1094	1.901e-68	243.0	COG1269@1|root,COG1269@2|Bacteria,1QGFB@1224|Proteobacteria,42SY2@68525|delta/epsilon subdivisions,2X5C4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	V-type ATPase 116kDa subunit family	-	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
CH3_k127_4273488_0	909663.KI867150_gene1095	1.771e-108	361.0	COG1527@1|root,COG1527@2|Bacteria	2|Bacteria	C	subunit (C	ntpC	-	-	ko:K02119	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_AC39
CH3_k127_4273488_4	909663.KI867150_gene1096	4.235e-19	93.0	294CD@1|root,2ZRSF@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_4273488_3	945713.IALB_0431	1.146e-52	194.0	COG1102@1|root,COG1102@2|Bacteria	2|Bacteria	F	Psort location Cytoplasmic, score	-	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin2
CH3_k127_4273488_1	497964.CfE428DRAFT_1398	1.136e-101	340.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,46U11@74201|Verrucomicrobia	74201|Verrucomicrobia	CG	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
CH3_k127_4282534_2	575540.Isop_2812	1.242e-14	79.0	COG0673@1|root,COG0673@2|Bacteria,2IX34@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CH3_k127_4282534_3	493475.GARC_4248	3.617e-07	58.0	2EH3D@1|root,33AVD@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3592)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3592
CH3_k127_4282534_1	314230.DSM3645_09917	1.605e-23	111.0	COG1082@1|root,COG1082@2|Bacteria,2J21B@203682|Planctomycetes	203682|Planctomycetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CH3_k127_4282534_0	742725.HMPREF9450_01216	5.614e-74	262.0	COG1082@1|root,COG1082@2|Bacteria,4NEWC@976|Bacteroidetes,2FQVH@200643|Bacteroidia,22UTI@171550|Rikenellaceae	976|Bacteroidetes	G	Glycosyl-hydrolase 97 N-terminal	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	GH97_C,GH97_N,Glyco_hydro_97
CH3_k127_4321086_0	797210.Halxa_4269	2.743e-41	160.0	COG2189@1|root,arCOG00108@2157|Archaea,2XUPX@28890|Euryarchaeota,23TS9@183963|Halobacteria	183963|Halobacteria	L	DNA methylase	-	-	2.1.1.72	ko:K07316	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
CH3_k127_4321086_3	935567.JAES01000002_gene626	1.79e-05	51.0	2EGKD@1|root,33ACM@2|Bacteria,1NAVJ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_4321086_2	670307.HYPDE_29893	1.086e-05	54.0	2FH9D@1|root,3493Q@2|Bacteria,1ND9G@1224|Proteobacteria,2UJ2Y@28211|Alphaproteobacteria,3N997@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
CH3_k127_4321086_1	686340.Metal_2200	7.383e-40	161.0	2C6BE@1|root,32XBJ@2|Bacteria,1NB89@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_4340444_5	1397527.Q670_02705	7.297e-23	109.0	COG3637@1|root,COG3637@2|Bacteria,1NE9Q@1224|Proteobacteria,1T3ZI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_4340444_1	1267534.KB906760_gene1239	1.071e-142	466.0	COG4325@1|root,COG4325@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2254
CH3_k127_4340444_3	1267533.KB906737_gene1998	2.377e-50	187.0	2E3FB@1|root,32YE4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_4340444_2	1298867.AUES01000063_gene24	1.419e-59	226.0	COG1814@1|root,COG1814@2|Bacteria,1R469@1224|Proteobacteria,2U4KR@28211|Alphaproteobacteria,3JUX4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
CH3_k127_4340444_0	497964.CfE428DRAFT_0248	5.412e-187	589.0	COG0387@1|root,COG0387@2|Bacteria,46UPT@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Sodium/calcium exchanger protein	-	-	-	-	-	-	-	-	-	-	-	-	Na_Ca_ex
CH3_k127_4340444_4	768671.ThimaDRAFT_0622	4.582e-49	186.0	COG0584@1|root,COG0584@2|Bacteria,1MU8H@1224|Proteobacteria,1RQWX@1236|Gammaproteobacteria,1WZGU@135613|Chromatiales	135613|Chromatiales	C	PFAM Glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
CH3_k127_4340444_6	395495.Lcho_0773	4.098e-05	46.0	COG3335@1|root,COG3335@2|Bacteria,1N5WI@1224|Proteobacteria,2VHUB@28216|Betaproteobacteria,1KPAP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
CH3_k127_4340583_1	1123070.KB899254_gene1274	3.935e-61	217.0	COG1974@1|root,COG1974@2|Bacteria,46SU8@74201|Verrucomicrobia,2IU8D@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KT	LexA DNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LexA_DNA_bind,Peptidase_S24
CH3_k127_4340583_2	1123508.JH636440_gene2371	2.702e-35	137.0	2CCSR@1|root,32RWC@2|Bacteria,2J1M5@203682|Planctomycetes	203682|Planctomycetes	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
CH3_k127_4340583_0	452637.Oter_3175	2.103e-83	300.0	COG0389@1|root,COG0389@2|Bacteria,46SNK@74201|Verrucomicrobia,3K7SQ@414999|Opitutae	414999|Opitutae	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
CH3_k127_4351263_8	1340493.JNIF01000003_gene4360	3.964e-16	88.0	COG5549@1|root,COG5549@2|Bacteria	2|Bacteria	O	protein import	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM60,Cu-binding_MopE,DUF4214,Peptidase_M10,Peptidase_S8
CH3_k127_4351263_4	1125863.JAFN01000001_gene972	2.923e-41	162.0	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,42T2J@68525|delta/epsilon subdivisions,2WPPV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	PFAM OmpA MotB domain protein	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
CH3_k127_4351263_3	472759.Nhal_3844	3.432e-64	226.0	COG0500@1|root,COG2226@2|Bacteria,1RDI3@1224|Proteobacteria,1S423@1236|Gammaproteobacteria,1WWQ9@135613|Chromatiales	135613|Chromatiales	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25
CH3_k127_4351263_5	997346.HMPREF9374_0351	4.48e-41	164.0	COG1597@1|root,COG1597@2|Bacteria,1TQJH@1239|Firmicutes,4HJ8D@91061|Bacilli,27BZ5@186824|Thermoactinomycetaceae	91061|Bacilli	I	Diacylglycerol kinase catalytic domain (presumed)	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
CH3_k127_4351263_1	481448.Minf_1814	3.136e-261	823.0	COG0556@1|root,COG0556@2|Bacteria,46SF2@74201|Verrucomicrobia,37GG7@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
CH3_k127_4351263_10	316274.Haur_2191	5.917e-10	66.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	2.7.11.1	ko:K11904,ko:K12132	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02044	3.A.23.1	-	-	DUF1565,DUF3494,Pkinase,SLH,TadE
CH3_k127_4351263_7	870187.Thini_1532	2.904e-17	94.0	COG2911@1|root,COG2911@2|Bacteria	2|Bacteria	S	protein secretion	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cadherin,Cadherin_3,Calx-beta,DUF4347,He_PIG,Invasin_D3,Laminin_G_3,Lectin_C,PA14,Pentaxin,Peptidase_S74
CH3_k127_4351263_9	324602.Caur_0299	3.475e-11	75.0	COG5295@1|root,COG5295@2|Bacteria,2GB82@200795|Chloroflexi,377IZ@32061|Chloroflexia	32061|Chloroflexia	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectinesterase
CH3_k127_4351263_6	1123247.AUIJ01000005_gene313	2.267e-29	130.0	COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,2TSJG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	membrane protein (homolog of Drosophila rhomboid)	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
CH3_k127_4351263_2	497964.CfE428DRAFT_2729	5.005e-74	257.0	COG1209@1|root,COG1209@2|Bacteria,46T9Q@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Nucleotidyl transferase	-	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
CH3_k127_4351263_0	1403819.BATR01000007_gene203	4.608e-269	863.0	COG1413@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cytochrom_C,DUF1080,GSDH,HEAT_2,Laminin_G_3,Lipase_GDSL_2,ThuA
CH3_k127_4374624_1	794903.OPIT5_07185	1.333e-108	368.0	COG0745@1|root,COG2208@1|root,COG0745@2|Bacteria,COG2208@2|Bacteria,46V2T@74201|Verrucomicrobia,3K9RQ@414999|Opitutae	414999|Opitutae	T	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	Response_reg,SpoIIE
CH3_k127_4374624_3	395961.Cyan7425_0748	5.016e-52	186.0	COG0745@1|root,COG0745@2|Bacteria,1G6W5@1117|Cyanobacteria	1117|Cyanobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CH3_k127_4374624_0	1173027.Mic7113_4161	2.814e-166	586.0	COG2199@1|root,COG2202@1|root,COG5002@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria,COG5002@2|Bacteria,1GQ1T@1117|Cyanobacteria,1HHSH@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,Response_reg
CH3_k127_4374624_2	234267.Acid_4291	1.309e-66	232.0	COG0642@1|root,COG2199@1|root,COG2770@1|root,COG2205@2|Bacteria,COG2770@2|Bacteria,COG3706@2|Bacteria,3Y9AN@57723|Acidobacteria	57723|Acidobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
CH3_k127_4380906_2	1123508.JH636439_gene737	1.112e-77	269.0	COG1409@1|root,COG1409@2|Bacteria	1123508.JH636439_gene737|-	S	acid phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_4380906_3	382464.ABSI01000005_gene1100	8.784e-38	147.0	COG0735@1|root,COG0735@2|Bacteria,46W8N@74201|Verrucomicrobia,2IUJS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Ferric uptake regulator family	-	-	-	ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
CH3_k127_4380906_0	234267.Acid_7699	3.337e-266	824.0	COG0719@1|root,COG0719@2|Bacteria,3Y2IX@57723|Acidobacteria	57723|Acidobacteria	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
CH3_k127_4380906_1	945713.IALB_2894	4.207e-113	370.0	COG0396@1|root,COG0396@2|Bacteria	2|Bacteria	O	ATPase activity	sufC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	iECH74115_1262.ECH74115_2396,iECIAI1_1343.ECIAI1_1734,iECIAI39_1322.ECIAI39_1376,iECSP_1301.ECSP_2249,iECs_1301.ECs2389,iEcSMS35_1347.EcSMS35_1514,iG2583_1286.G2583_2077,iSFV_1184.SFV_1705,iSFxv_1172.SFxv_1919,iSSON_1240.SSON_1474,iS_1188.S1844,iZ_1308.Z2710	ABC_tran
CH3_k127_4391689_2	583355.Caka_3065	4.235e-105	365.0	COG0768@1|root,COG0768@2|Bacteria,46SEZ@74201|Verrucomicrobia,3K799@414999|Opitutae	414999|Opitutae	M	Penicillin binding protein transpeptidase domain	-	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
CH3_k127_4391689_9	1121472.AQWN01000001_gene239	2.161e-41	164.0	COG2859@1|root,COG2859@2|Bacteria,1V1Q4@1239|Firmicutes,24GEE@186801|Clostridia,264GJ@186807|Peptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF541)	-	-	-	ko:K09797	-	-	-	-	ko00000	-	-	-	SIMPL
CH3_k127_4391689_4	497964.CfE428DRAFT_2938	4.256e-93	322.0	COG0770@1|root,COG0770@2|Bacteria,46SDF@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CH3_k127_4391689_3	794903.OPIT5_03555	2.54e-104	351.0	COG0472@1|root,COG0472@2|Bacteria,46SD0@74201|Verrucomicrobia,3K7EK@414999|Opitutae	414999|Opitutae	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
CH3_k127_4391689_11	1408422.JHYF01000017_gene1849	7.868e-19	95.0	COG1388@1|root,COG1388@2|Bacteria,1V10C@1239|Firmicutes	1239|Firmicutes	M	PFAM LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
CH3_k127_4391689_7	497964.CfE428DRAFT_2934	1.073e-73	262.0	COG0772@1|root,COG0772@2|Bacteria,46SMC@74201|Verrucomicrobia	74201|Verrucomicrobia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
CH3_k127_4391689_8	497964.CfE428DRAFT_2933	5.031e-66	243.0	COG0707@1|root,COG0707@2|Bacteria,46S84@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
CH3_k127_4391689_5	1156937.MFUM_1050006	2.139e-86	297.0	COG0773@1|root,COG0812@1|root,COG0773@2|Bacteria,COG0812@2|Bacteria,46SCG@74201|Verrucomicrobia,37G48@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	Mur ligase family, catalytic domain	murB	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_4,MurB_C,Mur_ligase,Mur_ligase_C,Mur_ligase_M
CH3_k127_4391689_6	478741.JAFS01000001_gene1134	1.741e-78	273.0	COG1181@1|root,COG1181@2|Bacteria,46UZ2@74201|Verrucomicrobia,37GF6@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	F	D-ala D-ala ligase N-terminus	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
CH3_k127_4391689_12	478741.JAFS01000001_gene1135	5.371e-18	95.0	COG1589@1|root,COG1589@2|Bacteria,46T4T@74201|Verrucomicrobia,37GQX@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	D	Cell division protein FtsQ	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
CH3_k127_4391689_1	497964.CfE428DRAFT_2928	2.207e-108	366.0	COG0849@1|root,COG0849@2|Bacteria,46SQI@74201|Verrucomicrobia	74201|Verrucomicrobia	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
CH3_k127_4391689_10	497964.CfE428DRAFT_2927	7.044e-30	135.0	COG0206@1|root,COG0206@2|Bacteria,46UWD@74201|Verrucomicrobia	74201|Verrucomicrobia	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
CH3_k127_4391689_0	1396418.BATQ01000141_gene3343	1.278e-192	610.0	COG4946@1|root,COG4946@2|Bacteria,46TXN@74201|Verrucomicrobia,2IV9W@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Tricorn protease homolog	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_4392226_2	313603.FB2170_10111	2.757e-48	202.0	COG3055@1|root,COG3204@1|root,COG3291@1|root,COG3055@2|Bacteria,COG3204@2|Bacteria,COG3291@2|Bacteria,4NHHD@976|Bacteroidetes,1HWPE@117743|Flavobacteriia,2PGXB@252356|Maribacter	976|Bacteroidetes	M	Di-glucose binding within endoplasmic reticulum	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Kelch_1,Kelch_6,Malectin,PKD
CH3_k127_4392226_1	1396141.BATP01000043_gene1929	2.83e-90	341.0	COG5337@1|root,COG5337@2|Bacteria,46ZJW@74201|Verrucomicrobia,2IVD0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
CH3_k127_4392226_4	1396141.BATP01000059_gene2520	3.86e-23	119.0	COG1404@1|root,COG2133@1|root,COG3055@1|root,COG3204@1|root,COG3506@1|root,COG3897@1|root,COG4733@1|root,COG1404@2|Bacteria,COG2133@2|Bacteria,COG3055@2|Bacteria,COG3204@2|Bacteria,COG3506@2|Bacteria,COG3897@2|Bacteria,COG4733@2|Bacteria,46TW3@74201|Verrucomicrobia,2IVDX@203494|Verrucomicrobiae	2|Bacteria	G	Glucose / Sorbosone dehydrogenase	psrP1	-	1.11.1.5,3.1.3.8,4.2.2.2	ko:K00428,ko:K01083,ko:K01728	ko00040,ko00562,ko02024,map00040,map00562,map02024	-	R02361,R03371,R06240	RC00049,RC00078,RC00705	ko00000,ko00001,ko01000	-	-	-	GSDH,Laminin_G_3,Malectin
CH3_k127_4392226_5	1121957.ATVL01000007_gene1972	2.386e-16	96.0	COG3291@1|root,COG3291@2|Bacteria,4NW5Z@976|Bacteroidetes	976|Bacteroidetes	C	alginic acid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
CH3_k127_4392226_6	661478.OP10G_1071	2.171e-12	78.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02650,ko:K02679	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10
CH3_k127_4392226_0	497964.CfE428DRAFT_4368	7.908e-211	674.0	COG1520@1|root,COG1520@2|Bacteria,46U89@74201|Verrucomicrobia	2|Bacteria	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566,PQQ_2,PQQ_3
CH3_k127_4392226_3	234267.Acid_6003	4.684e-46	183.0	COG2251@1|root,COG3316@1|root,COG2251@2|Bacteria,COG3316@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cas_Cas4,DDE_Tnp_IS66,HHH_5,RNase_H_2
CH3_k127_4401441_3	305700.B447_20945	1.459e-58	211.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,2VHUC@28216|Betaproteobacteria,2KV2M@206389|Rhodocyclales	206389|Rhodocyclales	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
CH3_k127_4401441_2	177437.HRM2_38050	2.063e-138	448.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,42Q5V@68525|delta/epsilon subdivisions,2WJA1@28221|Deltaproteobacteria,2MJ9S@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfk-1	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
CH3_k127_4401441_0	497964.CfE428DRAFT_0990	1.314e-262	829.0	COG0514@1|root,COG0514@2|Bacteria,46S7V@74201|Verrucomicrobia	74201|Verrucomicrobia	L	TIGRFAM ATP-dependent DNA helicase, RecQ family	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
CH3_k127_4401441_1	1121438.JNJA01000001_gene2267	1.48e-223	714.0	COG0531@1|root,COG0531@2|Bacteria,1R829@1224|Proteobacteria,42MS5@68525|delta/epsilon subdivisions,2WINQ@28221|Deltaproteobacteria,2M85I@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
CH3_k127_4433491_0	1304880.JAGB01000002_gene1563	2.671e-89	301.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CH3_k127_4433491_1	481448.Minf_0649	1.14e-18	87.0	COG3071@1|root,COG3071@2|Bacteria,46TBM@74201|Verrucomicrobia,37H13@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	H	Protein of unknown function (DUF2905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2905
CH3_k127_4463837_4	1210045.ALNP01000010_gene1141	1.497e-36	143.0	COG0178@1|root,COG0178@2|Bacteria,2GJUV@201174|Actinobacteria	201174|Actinobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	GO:0000018,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0071944,GO:0080090	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
CH3_k127_4463837_0	452637.Oter_3889	8.157e-147	471.0	COG2025@1|root,COG2025@2|Bacteria	2|Bacteria	C	fatty acid beta-oxidation using acyl-CoA dehydrogenase	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	Acyl-CoA_dh_1,ETF,ETF_alpha
CH3_k127_4463837_2	794903.OPIT5_18130	1.666e-43	162.0	COG0614@1|root,COG0614@2|Bacteria	2|Bacteria	P	abc-type fe3 -hydroxamate transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
CH3_k127_4463837_1	452637.Oter_3888	5.19e-129	416.0	COG2086@1|root,COG2086@2|Bacteria	2|Bacteria	C	electron transfer activity	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
CH3_k127_4463837_5	794903.OPIT5_04755	3.178e-20	93.0	COG2152@1|root,COG2152@2|Bacteria,46YKJ@74201|Verrucomicrobia,3K8SE@414999|Opitutae	2|Bacteria	G	beta-1,4-mannooligosaccharide phosphorylase	-	-	2.4.1.339,2.4.1.340	ko:K20885	-	-	R11397,R11398	RC00049,RC02748	ko00000,ko01000	-	GH130	-	Glyco_hydro_130
CH3_k127_4488845_1	481448.Minf_0686	4.561e-109	359.0	COG0090@1|root,COG0090@2|Bacteria,46S71@74201|Verrucomicrobia,37FZV@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
CH3_k127_4488845_11	794903.OPIT5_02410	2.291e-34	133.0	COG0185@1|root,COG0185@2|Bacteria,46T4G@74201|Verrucomicrobia,3K87G@414999|Opitutae	414999|Opitutae	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
CH3_k127_4488845_15	497964.CfE428DRAFT_0492	1.696e-23	105.0	COG0091@1|root,COG0091@2|Bacteria,46T5F@74201|Verrucomicrobia	74201|Verrucomicrobia	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
CH3_k127_4488845_2	452637.Oter_0220	5.641e-87	298.0	COG0092@1|root,COG0092@2|Bacteria,46SN9@74201|Verrucomicrobia,3K776@414999|Opitutae	414999|Opitutae	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
CH3_k127_4488845_7	497964.CfE428DRAFT_0494	4.228e-54	193.0	COG0197@1|root,COG0197@2|Bacteria,46ST6@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
CH3_k127_4488845_18	349741.Amuc_0295	0.0001941	51.0	COG0255@1|root,COG0255@2|Bacteria,46TAV@74201|Verrucomicrobia,2IUWM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal L29 protein	-	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
CH3_k127_4488845_14	1403819.BATR01000164_gene5565	1.51e-26	111.0	COG0186@1|root,COG0186@2|Bacteria,46T6M@74201|Verrucomicrobia,2IUPS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
CH3_k127_4488845_9	1156937.MFUM_870033	8.151e-47	171.0	COG0093@1|root,COG0093@2|Bacteria,46VID@74201|Verrucomicrobia,37GRN@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
CH3_k127_4488845_16	382464.ABSI01000011_gene2659	3.926e-23	101.0	COG0198@1|root,COG0198@2|Bacteria,46T3M@74201|Verrucomicrobia,2IUUE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal proteins 50S L24/mitochondrial 39S L24	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
CH3_k127_4488845_5	635013.TherJR_0308	6.692e-60	212.0	COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,247X0@186801|Clostridia,2603I@186807|Peptococcaceae	186801|Clostridia	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
CH3_k127_4488845_12	1403819.BATR01000162_gene5349	2.62e-31	124.0	COG0199@1|root,COG0199@2|Bacteria,46TBH@74201|Verrucomicrobia,2IUM9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
CH3_k127_4488845_10	265311.Mfl137	3.903e-40	152.0	COG0096@1|root,COG0096@2|Bacteria,3WTD8@544448|Tenericutes	544448|Tenericutes	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
CH3_k127_4488845_4	240016.ABIZ01000001_gene4064	9.286e-68	234.0	COG0097@1|root,COG0097@2|Bacteria,46SP9@74201|Verrucomicrobia,2IU69@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
CH3_k127_4488845_13	771875.Ferpe_1400	1.86e-28	119.0	COG0256@1|root,COG0256@2|Bacteria,2GD32@200918|Thermotogae	200918|Thermotogae	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
CH3_k127_4488845_6	497964.CfE428DRAFT_0503	5.038e-57	205.0	COG0098@1|root,COG0098@2|Bacteria,46SUR@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
CH3_k127_4488845_8	497964.CfE428DRAFT_0504	7.383e-49	179.0	COG0200@1|root,COG0200@2|Bacteria,46SSX@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
CH3_k127_4488845_0	452637.Oter_0207	2.821e-151	491.0	COG0201@1|root,COG0201@2|Bacteria,46S86@74201|Verrucomicrobia,3K7NJ@414999|Opitutae	414999|Opitutae	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
CH3_k127_4488845_3	497964.CfE428DRAFT_0506	4.038e-84	286.0	COG0024@1|root,COG0024@2|Bacteria,46SK6@74201|Verrucomicrobia	74201|Verrucomicrobia	J	TIGRFAM methionine aminopeptidase, type I	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
CH3_k127_4488845_17	1089553.Tph_c25620	1.041e-05	48.0	COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,24MQE@186801|Clostridia,42GRV@68295|Thermoanaerobacterales	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
CH3_k127_4504818_3	484018.BACPLE_03677	3.409e-18	90.0	COG3250@1|root,COG3250@2|Bacteria,4NFE8@976|Bacteroidetes,2FPEC@200643|Bacteroidia,4AKUZ@815|Bacteroidaceae	976|Bacteroidetes	G	Glycosyl hydrolase family 2, sugar binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106,Glyco_hydro_2_N
CH3_k127_4504818_0	997884.HMPREF1068_03968	5.314e-151	515.0	COG3250@1|root,COG5492@1|root,COG3250@2|Bacteria,COG5492@2|Bacteria,4PKXA@976|Bacteroidetes,2FP7W@200643|Bacteroidia,4AN8Z@815|Bacteroidaceae	976|Bacteroidetes	G	Bacterial alpha-L-rhamnosidase C-terminal domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N,Lyase_8,Lyase_8_C,Lyase_8_N
CH3_k127_4504818_1	272560.BPSS1454	7.288e-69	246.0	COG0388@1|root,COG0388@2|Bacteria,1NSBY@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF3326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3326
CH3_k127_4504818_2	521674.Plim_3912	4.6e-35	134.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2J2KJ@203682|Planctomycetes	203682|Planctomycetes	EU	Dipeptidyl peptidase IV (DPP IV) N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DPPIV_N,Peptidase_S9
CH3_k127_4532217_3	1192034.CAP_0893	1.388e-77	270.0	COG3509@1|root,COG3509@2|Bacteria,1N6M6@1224|Proteobacteria,42U8Z@68525|delta/epsilon subdivisions,2WQQT@28221|Deltaproteobacteria,2YV47@29|Myxococcales	28221|Deltaproteobacteria	Q	Esterase PHB depolymerase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Esterase_phd
CH3_k127_4532217_4	1137269.AZWL01000013_gene2716	1.97e-24	121.0	COG3537@1|root,COG3537@2|Bacteria,2GKYM@201174|Actinobacteria	201174|Actinobacteria	G	Alpha-1,2-mannosidase	-	-	-	-	-	-	-	-	-	-	-	-	CBM-like,Glyco_hydro_92,NPCBM_assoc
CH3_k127_4532217_0	1267533.KB906735_gene4670	2.282e-284	913.0	COG0383@1|root,COG0383@2|Bacteria	2|Bacteria	G	mannose metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
CH3_k127_4532217_2	278957.ABEA03000005_gene4380	9.966e-169	539.0	COG0407@1|root,COG0407@2|Bacteria,46WW7@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
CH3_k127_4532217_1	1267535.KB906767_gene3746	8.791e-197	660.0	COG0383@1|root,COG0383@2|Bacteria	2|Bacteria	G	mannose metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-mann_mid,CBM-like,Glyco_hydro_38,Glyco_hydro_38C
CH3_k127_4534945_5	1121904.ARBP01000033_gene3213	5.317e-31	135.0	28K60@1|root,2Z9UH@2|Bacteria,4NHE6@976|Bacteroidetes,47UNS@768503|Cytophagia	976|Bacteroidetes	S	Methane oxygenase PmoA	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
CH3_k127_4534945_3	1168034.FH5T_12675	4.758e-46	178.0	2CI12@1|root,338T1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_4534945_2	370438.PTH_1296	4.205e-102	353.0	COG0621@1|root,COG0621@2|Bacteria,1TP2W@1239|Firmicutes,2487D@186801|Clostridia,26141@186807|Peptococcaceae	186801|Clostridia	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
CH3_k127_4534945_4	903814.ELI_2067	2.306e-38	151.0	COG0558@1|root,COG0558@2|Bacteria,1V6PJ@1239|Firmicutes,24J7Y@186801|Clostridia,25W8B@186806|Eubacteriaceae	186801|Clostridia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	-	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
CH3_k127_4534945_6	1123267.JONN01000001_gene1815	7.056e-11	69.0	COG1426@1|root,COG1426@2|Bacteria,1ND8D@1224|Proteobacteria,2UB49@28211|Alphaproteobacteria,2K57P@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF4115)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4115,HTH_25
CH3_k127_4534945_0	1210884.HG799462_gene7951	1.041e-233	730.0	COG4102@1|root,COG4102@2|Bacteria,2IX5T@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CH3_k127_4534945_1	1210884.HG799462_gene7952	2.498e-152	492.0	COG2010@1|root,COG2010@2|Bacteria,2J53S@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
CH3_k127_4539071_1	497964.CfE428DRAFT_1618	2.942e-169	538.0	COG0104@1|root,COG0104@2|Bacteria,46TDF@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
CH3_k127_4539071_10	365046.Rta_17060	8.035e-20	102.0	COG4447@1|root,COG4447@2|Bacteria,1PIDF@1224|Proteobacteria,2WBU7@28216|Betaproteobacteria,4AIC2@80864|Comamonadaceae	28216|Betaproteobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_4539071_4	1403819.BATR01000184_gene6352	2.7e-92	309.0	COG0020@1|root,COG0020@2|Bacteria,46SMY@74201|Verrucomicrobia,2IU5V@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	-	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
CH3_k127_4539071_6	497964.CfE428DRAFT_4834	3.115e-60	219.0	COG4589@1|root,COG4589@2|Bacteria,46SX9@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Cytidylyltransferase family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
CH3_k127_4539071_2	1396418.BATQ01000139_gene3250	9.547e-140	454.0	COG0743@1|root,COG0743@2|Bacteria,46S90@74201|Verrucomicrobia,2ITI1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
CH3_k127_4539071_5	452637.Oter_4633	1.095e-72	263.0	COG0750@1|root,COG0750@2|Bacteria,46S9B@74201|Verrucomicrobia,3K73Q@414999|Opitutae	414999|Opitutae	M	zinc metalloprotease	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
CH3_k127_4539071_0	497964.CfE428DRAFT_4831	8.142e-240	755.0	COG0821@1|root,COG0821@2|Bacteria,46SEF@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
CH3_k127_4539071_9	1173025.GEI7407_1434	5.655e-21	100.0	COG3832@1|root,COG3832@2|Bacteria,1G83T@1117|Cyanobacteria,1HDP1@1150|Oscillatoriales	1117|Cyanobacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_4539071_8	497964.CfE428DRAFT_4583	5.377e-29	129.0	COG1381@1|root,COG1381@2|Bacteria,46VUW@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
CH3_k127_4539071_7	1449126.JQKL01000073_gene3044	1.052e-41	162.0	COG2928@1|root,COG2928@2|Bacteria,1V6FM@1239|Firmicutes,24JQ1@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
CH3_k127_4539071_11	945713.IALB_1565	2.536e-11	74.0	COG0319@1|root,COG0319@2|Bacteria	2|Bacteria	C	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141	2.6.99.2,3.5.4.5	ko:K01489,ko:K03474,ko:K03595,ko:K07042	ko00240,ko00750,ko00983,ko01100,map00240,map00750,map00983,map01100	M00124	R01878,R02485,R05838,R08221	RC00074,RC00514,RC01476	ko00000,ko00001,ko00002,ko01000,ko03009,ko03029	-	-	-	UPF0054
CH3_k127_4539071_3	497964.CfE428DRAFT_6337	6.73e-117	384.0	COG1702@1|root,COG1702@2|Bacteria,46S7S@74201|Verrucomicrobia	74201|Verrucomicrobia	T	PhoH-like protein	-	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
CH3_k127_4541589_0	1267535.KB906767_gene1026	2.422e-72	258.0	COG0673@1|root,COG0673@2|Bacteria,3Y6VS@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CH3_k127_4541589_1	349161.Dred_2340	4.659e-31	126.0	COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,247MS@186801|Clostridia,260XG@186807|Peptococcaceae	186801|Clostridia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
CH3_k127_4543903_12	278957.ABEA03000021_gene1719	1.839e-08	68.0	COG1520@1|root,COG1520@2|Bacteria,46Z5C@74201|Verrucomicrobia,3K9I4@414999|Opitutae	414999|Opitutae	S	Immunoglobulin	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_4543903_10	1469557.JSWF01000021_gene726	1.96e-21	111.0	COG0739@1|root,COG3266@1|root,COG4886@1|root,COG0739@2|Bacteria,COG3266@2|Bacteria,COG4886@2|Bacteria,4NMJ3@976|Bacteroidetes,1I2GQ@117743|Flavobacteriia	976|Bacteroidetes	P	leucine- rich repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
CH3_k127_4543903_5	306281.AJLK01000102_gene3405	2.005e-71	246.0	COG2258@1|root,COG2258@2|Bacteria,1GE7I@1117|Cyanobacteria	1117|Cyanobacteria	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_4543903_1	886293.Sinac_6925	2.244e-163	527.0	COG0399@1|root,COG0399@2|Bacteria,2IYSK@203682|Planctomycetes	203682|Planctomycetes	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
CH3_k127_4543903_3	240016.ABIZ01000001_gene3537	1.198e-138	481.0	COG0553@1|root,COG0553@2|Bacteria,46YZ0@74201|Verrucomicrobia,2ITIC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
CH3_k127_4543903_15	1214217.ALNF01000014_gene1478	5.664e-05	53.0	COG3944@1|root,COG3944@2|Bacteria,1V4ZF@1239|Firmicutes,4IR4A@91061|Bacilli,1WSAY@1307|Streptococcus suis	91061|Bacilli	M	Chain length determinant protein	cps4C	-	-	-	-	-	-	-	-	-	-	-	Wzz
CH3_k127_4543903_13	497321.C664_02540	4.8e-08	55.0	COG2008@1|root,COG2008@2|Bacteria,1MWCR@1224|Proteobacteria,2VK17@28216|Betaproteobacteria,2KY4N@206389|Rhodocyclales	206389|Rhodocyclales	E	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde	-	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
CH3_k127_4543903_4	313590.MED134_09431	8.356e-98	328.0	COG2374@1|root,COG2374@2|Bacteria,4NI8T@976|Bacteroidetes,1I0TH@117743|Flavobacteriia	976|Bacteroidetes	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CH3_k127_4543903_0	1123278.KB893448_gene1541	6.089e-192	616.0	COG0154@1|root,COG0154@2|Bacteria,4NF8C@976|Bacteroidetes,47KZQ@768503|Cytophagia	976|Bacteroidetes	J	Amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
CH3_k127_4543903_7	1279009.ADICEAN_02097	1.313e-33	145.0	COG0823@1|root,COG1649@1|root,COG2931@1|root,COG3055@1|root,COG3210@1|root,COG4733@1|root,COG0823@2|Bacteria,COG1649@2|Bacteria,COG2931@2|Bacteria,COG3055@2|Bacteria,COG3210@2|Bacteria,COG4733@2|Bacteria,4NPRK@976|Bacteroidetes	976|Bacteroidetes	U	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_4543903_11	1197906.CAJQ02000023_gene2158	1.083e-12	80.0	COG2335@1|root,COG2335@2|Bacteria,1MZ8G@1224|Proteobacteria,2U5ZN@28211|Alphaproteobacteria,3JY4R@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	A domain in the BMP inhibitor chordin and in microbial proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
CH3_k127_4543903_9	1232410.KI421415_gene3082	6.647e-31	125.0	COG1193@1|root,COG1193@2|Bacteria,1NCS6@1224|Proteobacteria,42VGJ@68525|delta/epsilon subdivisions,2WRA6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM Smr protein MutS2	-	-	-	-	-	-	-	-	-	-	-	-	Smr
CH3_k127_4543903_6	1210884.HG799462_gene8139	3.774e-43	164.0	COG0454@1|root,COG0456@2|Bacteria,2J028@203682|Planctomycetes	203682|Planctomycetes	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CH3_k127_4543903_2	926549.KI421517_gene2208	1.169e-162	523.0	COG1473@1|root,COG1473@2|Bacteria,4NGBI@976|Bacteroidetes,47NGQ@768503|Cytophagia	976|Bacteroidetes	S	Peptidase dimerisation domain	-	-	3.5.1.32	ko:K01451	ko00360,map00360	-	R01424	RC00096,RC00162	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
CH3_k127_4543903_8	886293.Sinac_4672	5.172e-32	131.0	COG1403@1|root,COG1403@2|Bacteria,2J3RR@203682|Planctomycetes	203682|Planctomycetes	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH
CH3_k127_4549547_3	1123508.JH636440_gene2839	3.733e-63	226.0	COG2304@1|root,COG2304@2|Bacteria,2IYXD@203682|Planctomycetes	203682|Planctomycetes	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA
CH3_k127_4549547_4	497964.CfE428DRAFT_1718	4.713e-59	207.0	COG3558@1|root,COG3558@2|Bacteria,46VBZ@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF5069)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5069
CH3_k127_4549547_0	497964.CfE428DRAFT_3635	1.031e-141	474.0	COG0782@1|root,COG1747@1|root,COG0782@2|Bacteria,COG1747@2|Bacteria,46S7F@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	-	-	-	-	-	-	-	-	-	GreA_GreB,GreA_GreB_N
CH3_k127_4549547_1	55529.EKX47288	1.371e-101	350.0	COG0144@1|root,KOG1122@2759|Eukaryota	2759|Eukaryota	J	rRNA (cytosine-C5-)-methyltransferase activity	-	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
CH3_k127_4549547_5	382464.ABSI01000007_gene4120	1.931e-12	74.0	2F78F@1|root,33ZPQ@2|Bacteria,46VT2@74201|Verrucomicrobia,2IURV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_4549547_2	28072.Nos7524_0364	4.93e-76	259.0	COG0412@1|root,COG0412@2|Bacteria,1G4HV@1117|Cyanobacteria,1HMQR@1161|Nostocales	1117|Cyanobacteria	Q	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DLH
CH3_k127_4560827_0	489825.LYNGBM3L_48690	1.356e-51	197.0	COG1262@1|root,COG1262@2|Bacteria,1GBNA@1117|Cyanobacteria	1117|Cyanobacteria	D	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,TPR_2
CH3_k127_4560827_3	234267.Acid_2488	1.036e-09	63.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CH3_k127_4560827_2	1337936.IJ00_01065	4.106e-27	130.0	COG1672@1|root,COG2319@1|root,COG1672@2|Bacteria,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria	1117|Cyanobacteria	A	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,WD40
CH3_k127_4560827_1	1210884.HG799470_gene14309	1.221e-29	138.0	COG0515@1|root,COG0515@2|Bacteria,2IXZY@203682|Planctomycetes	203682|Planctomycetes	T	COG0515 Serine threonine protein	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_10,TPR_11,TPR_12,WD40
CH3_k127_458158_1	382464.ABSI01000005_gene1296	1.019e-103	374.0	COG0457@1|root,COG0515@1|root,COG3291@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG3291@2|Bacteria,46UMT@74201|Verrucomicrobia,2IVH7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,PEGA,PG_binding_1,Pkinase
CH3_k127_458158_0	314230.DSM3645_14810	1.839e-111	373.0	COG1520@1|root,COG1520@2|Bacteria,2IX03@203682|Planctomycetes	203682|Planctomycetes	S	protein kinase related protein	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CH3_k127_458158_2	452637.Oter_3643	1.586e-86	300.0	COG0845@1|root,COG0845@2|Bacteria,46TJP@74201|Verrucomicrobia,3K7D1@414999|Opitutae	414999|Opitutae	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
CH3_k127_458271_2	765914.ThisiDRAFT_1573	1.654e-46	173.0	COG0778@1|root,COG0778@2|Bacteria	2|Bacteria	C	coenzyme F420-1:gamma-L-glutamate ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase,TM1586_NiRdase
CH3_k127_458271_1	278957.ABEA03000004_gene4552	2.714e-76	264.0	COG0553@1|root,COG0827@1|root,COG4646@1|root,COG0553@2|Bacteria,COG0827@2|Bacteria,COG4646@2|Bacteria,46Y61@74201|Verrucomicrobia,3K8ZZ@414999|Opitutae	414999|Opitutae	KL	DEAD-like helicases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	ResIII
CH3_k127_458271_4	278957.ABEA03000004_gene4552	2.639e-33	133.0	COG0553@1|root,COG0827@1|root,COG4646@1|root,COG0553@2|Bacteria,COG0827@2|Bacteria,COG4646@2|Bacteria,46Y61@74201|Verrucomicrobia,3K8ZZ@414999|Opitutae	414999|Opitutae	KL	DEAD-like helicases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	ResIII
CH3_k127_458271_6	1303518.CCALI_02579	8.909e-22	106.0	COG4537@1|root,COG4537@2|Bacteria	2|Bacteria	U	Required for transformation and DNA binding	comGC	GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944	-	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	M00331,M00429	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
CH3_k127_458271_5	1117315.AHCA01000001_gene2142	1.924e-32	148.0	COG3537@1|root,COG5492@1|root,COG3537@2|Bacteria,COG5492@2|Bacteria,1R4VD@1224|Proteobacteria,1RZJ5@1236|Gammaproteobacteria,2Q5IB@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	G	F5/8 type C domain	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C
CH3_k127_458271_8	1121373.KB903632_gene508	1.704e-11	79.0	COG1520@1|root,COG1520@2|Bacteria,4NNUN@976|Bacteroidetes,47Q36@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,I-set,Ig_3,SBBP
CH3_k127_458271_7	1123242.JH636434_gene4592	1.465e-15	92.0	COG3712@1|root,COG3712@2|Bacteria,2IZ99@203682|Planctomycetes	203682|Planctomycetes	PT	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR,Laminin_G_3
CH3_k127_458271_0	861299.J421_1753	1.155e-297	957.0	COG0446@1|root,COG4888@1|root,COG0446@2|Bacteria,COG4888@2|Bacteria	2|Bacteria	G	ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,Pyr_redox_2,UnbV_ASPIC,VCBS
CH3_k127_458271_3	1396141.BATP01000022_gene455	5.077e-34	141.0	COG4675@1|root,COG4675@2|Bacteria,46X85@74201|Verrucomicrobia,2IUYY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Phage Tail Collar Domain	-	-	-	-	-	-	-	-	-	-	-	-	Collar
CH3_k127_4602489_5	498761.HM1_0137	2.208e-10	74.0	COG1470@1|root,COG3210@1|root,COG4733@1|root,COG4886@1|root,COG5492@1|root,COG1470@2|Bacteria,COG3210@2|Bacteria,COG4733@2|Bacteria,COG4886@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_2,CHU_C,Flg_new,LRR_5,RCC1,SLH
CH3_k127_4602489_2	1123242.JH636435_gene2613	3.493e-58	211.0	COG1595@1|root,COG1595@2|Bacteria,2IZZP@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
CH3_k127_4602489_1	497964.CfE428DRAFT_0066	3.304e-71	265.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,46TTW@74201|Verrucomicrobia	74201|Verrucomicrobia	KLT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PEGA,Pkinase
CH3_k127_4602489_4	153948.NAL212_2874	1.397e-12	81.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,2VJ72@28216|Betaproteobacteria,371Z5@32003|Nitrosomonadales	28216|Betaproteobacteria	T	SMART Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
CH3_k127_4602489_6	1089545.KB913037_gene8403	4.086e-08	66.0	COG1404@1|root,COG4447@1|root,COG1404@2|Bacteria,COG4447@2|Bacteria,2HSAI@201174|Actinobacteria,4ED2E@85010|Pseudonocardiales	201174|Actinobacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_4602489_3	1218084.BBJK01000086_gene5778	1.15e-25	123.0	COG3250@1|root,COG3250@2|Bacteria,1QZHW@1224|Proteobacteria,2WI8K@28216|Betaproteobacteria,1KIR6@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Domain of unknown function (DUF4982)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4982,F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_64,I-set,Ig_3
CH3_k127_4602489_0	1396141.BATP01000060_gene4727	1.102e-224	741.0	COG0457@1|root,COG3712@1|root,COG0457@2|Bacteria,COG3712@2|Bacteria	2|Bacteria	PT	iron ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	FecR,TPR_16,TPR_19,TPR_8,TonB_dep_Rec
CH3_k127_4620249_3	278957.ABEA03000201_gene4321	0.0001665	53.0	COG1450@1|root,COG1450@2|Bacteria,46UJF@74201|Verrucomicrobia,3K7CH@414999|Opitutae	414999|Opitutae	NU	Type II and III secretion system protein	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
CH3_k127_4620249_1	1403819.BATR01000150_gene5071	1.473e-101	350.0	COG1570@1|root,COG1570@2|Bacteria,46SCN@74201|Verrucomicrobia,2ITK4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
CH3_k127_4620249_0	452637.Oter_2196	6.094e-149	488.0	COG0673@1|root,COG0673@2|Bacteria,46U95@74201|Verrucomicrobia,3K969@414999|Opitutae	414999|Opitutae	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CH3_k127_4620249_2	487796.Flav2ADRAFT_1690	1.265e-40	159.0	COG3291@1|root,COG3291@2|Bacteria,4NH7R@976|Bacteroidetes,1IJC3@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CH3_k127_462834_3	1123242.JH636434_gene4965	2.763e-150	492.0	COG0477@1|root,COG2814@2|Bacteria,2IYPH@203682|Planctomycetes	203682|Planctomycetes	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CH3_k127_462834_1	794903.OPIT5_20520	8.755e-169	545.0	COG0147@1|root,COG0147@2|Bacteria,46S4I@74201|Verrucomicrobia,3K72I@414999|Opitutae	414999|Opitutae	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
CH3_k127_462834_18	42256.RradSPS_3110	7.071e-15	76.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_462834_23	118166.JH976537_gene1582	1.793e-08	58.0	COG3210@1|root,COG3210@2|Bacteria,1G775@1117|Cyanobacteria,1HCW7@1150|Oscillatoriales	1117|Cyanobacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_462834_20	1183438.GKIL_3127	2.434e-13	72.0	2E6Q0@1|root,331A9@2|Bacteria,1G9WU@1117|Cyanobacteria	1117|Cyanobacteria	S	Domain of unknown function (DUF4926)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4926
CH3_k127_462834_22	266809.PM03_10895	1.471e-11	65.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,2TRWB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
CH3_k127_462834_10	111781.Lepto7376_0105	1.908e-72	262.0	COG1520@1|root,COG3210@1|root,COG3595@1|root,COG4995@1|root,COG1520@2|Bacteria,COG3210@2|Bacteria,COG3595@2|Bacteria,COG4995@2|Bacteria,1G08N@1117|Cyanobacteria,1H96Q@1150|Oscillatoriales	1117|Cyanobacteria	U	filamentous hemagglutinin family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,Haemagg_act,P_proprotein
CH3_k127_462834_21	794903.OPIT5_29985	1.128e-12	71.0	COG1533@1|root,COG1533@2|Bacteria	2|Bacteria	L	DNA photolyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
CH3_k127_462834_11	794903.OPIT5_29985	5.625e-71	252.0	COG1533@1|root,COG1533@2|Bacteria	2|Bacteria	L	DNA photolyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
CH3_k127_462834_19	338969.Rfer_1071	1.951e-14	83.0	COG1028@1|root,COG1028@2|Bacteria,1RBAD@1224|Proteobacteria,2VI9U@28216|Betaproteobacteria,4AA6I@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	Short-chain dehydrogenase reductase Sdr	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_462834_17	525904.Tter_1255	3.157e-17	85.0	COG0147@1|root,COG0147@2|Bacteria,2NNRD@2323|unclassified Bacteria	2|Bacteria	E	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
CH3_k127_462834_4	1125973.JNLC01000011_gene481	9.067e-144	469.0	COG0665@1|root,COG0665@2|Bacteria,1MUXJ@1224|Proteobacteria,2TRGS@28211|Alphaproteobacteria,3JXXJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
CH3_k127_462834_8	1123242.JH636434_gene5139	2.103e-93	318.0	COG2025@1|root,COG2025@2|Bacteria,2J3Y1@203682|Planctomycetes	203682|Planctomycetes	C	Electron transfer flavoprotein domain	-	-	-	-	-	-	-	-	-	-	-	-	ETF,ETF_alpha
CH3_k127_462834_9	1121106.JQKB01000007_gene972	3.723e-77	266.0	COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,2TR4J@28211|Alphaproteobacteria,2JPSB@204441|Rhodospirillales	204441|Rhodospirillales	C	Electron transfer flavoprotein, beta subunit	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
CH3_k127_462834_13	1380394.JADL01000001_gene2442	5.993e-58	217.0	COG0665@1|root,COG0665@2|Bacteria,1MUXJ@1224|Proteobacteria,2TRGS@28211|Alphaproteobacteria,2JREU@204441|Rhodospirillales	28211|Alphaproteobacteria	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
CH3_k127_462834_2	635013.TherJR_0057	1.174e-157	512.0	COG5598@1|root,COG5598@2|Bacteria,1V08E@1239|Firmicutes,24BDE@186801|Clostridia,263XC@186807|Peptococcaceae	186801|Clostridia	H	Trimethylamine methyltransferase	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
CH3_k127_462834_6	1116369.KB890025_gene5283	1.684e-112	377.0	COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,2TSJ5@28211|Alphaproteobacteria,43GYK@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	P	Rieske 2Fe-2S	-	-	-	ko:K00479	-	-	-	-	ko00000	-	-	-	Rieske,Ring_hydroxyl_A
CH3_k127_462834_7	1240350.AMZE01000024_gene1610	1.308e-98	338.0	COG2271@1|root,COG2271@2|Bacteria,1MX4V@1224|Proteobacteria,1RMB3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	transporter	-	-	-	ko:K07783	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.1.4.4,2.A.1.4.6	-	-	MFS_1
CH3_k127_462834_15	1123256.KB907940_gene188	2.547e-22	103.0	COG2839@1|root,COG2839@2|Bacteria,1MZEV@1224|Proteobacteria,1SAFY@1236|Gammaproteobacteria,1X6YB@135614|Xanthomonadales	135614|Xanthomonadales	S	protein conserved in bacteria	-	-	-	ko:K09793	-	-	-	-	ko00000	-	-	-	DUF456
CH3_k127_462834_0	452637.Oter_3619	1.348e-171	548.0	COG0334@1|root,COG0334@2|Bacteria,46S9K@74201|Verrucomicrobia,3K78F@414999|Opitutae	414999|Opitutae	C	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
CH3_k127_462834_12	1254432.SCE1572_15425	1.727e-64	229.0	COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,42RT9@68525|delta/epsilon subdivisions,2WNJ0@28221|Deltaproteobacteria,2YWKZ@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	iAF987.Gmet_1658	Fer4_14,Radical_SAM
CH3_k127_462834_5	1123070.KB899254_gene1284	2.44e-118	396.0	COG0160@1|root,COG0160@2|Bacteria,46UEH@74201|Verrucomicrobia,2IVU9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
CH3_k127_462834_16	879308.HMPREF9130_1176	2.427e-18	89.0	COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,248RY@186801|Clostridia,22GP0@1570339|Peptoniphilaceae	186801|Clostridia	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
CH3_k127_4639904_1	497964.CfE428DRAFT_4587	3.047e-232	725.0	COG2895@1|root,COG2895@2|Bacteria,46SN4@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	-	2.7.1.25,2.7.7.4	ko:K00955	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU
CH3_k127_4639904_2	452637.Oter_2430	6.826e-169	533.0	COG0175@1|root,COG0175@2|Bacteria,46TUQ@74201|Verrucomicrobia,3K7NR@414999|Opitutae	74201|Verrucomicrobia	H	PFAM phosphoadenosine phosphosulfate reductase	-	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
CH3_k127_4639904_5	497964.CfE428DRAFT_4585	1.996e-112	365.0	COG0175@1|root,COG0175@2|Bacteria,46SNE@74201|Verrucomicrobia	74201|Verrucomicrobia	EH	Phosphoadenosine phosphosulfate reductase family	-	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
CH3_k127_4639904_0	452637.Oter_2432	7.918e-259	807.0	COG0155@1|root,COG0155@2|Bacteria,46U85@74201|Verrucomicrobia,3K77C@414999|Opitutae	414999|Opitutae	C	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family	-	-	1.8.1.2	ko:K00381	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00858	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
CH3_k127_4639904_4	497964.CfE428DRAFT_4701	4.041e-116	388.0	COG0482@1|root,COG0482@2|Bacteria,46SQW@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
CH3_k127_4639904_3	1156937.MFUM_870060	6.498e-130	421.0	COG0462@1|root,COG0462@2|Bacteria,46SVH@74201|Verrucomicrobia,37GGN@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
CH3_k127_4639904_6	497964.CfE428DRAFT_1544	2.227e-55	204.0	COG1825@1|root,COG1825@2|Bacteria,46SZS@74201|Verrucomicrobia	74201|Verrucomicrobia	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
CH3_k127_4639904_7	111781.Lepto7376_3170	1.322e-49	184.0	COG0193@1|root,COG0193@2|Bacteria,1G0D0@1117|Cyanobacteria,1H70D@1150|Oscillatoriales	1117|Cyanobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
CH3_k127_4639904_9	478741.JAFS01000001_gene1845	8.799e-12	69.0	COG0360@1|root,COG0360@2|Bacteria,46TBG@74201|Verrucomicrobia,37GXZ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
CH3_k127_4639904_8	794903.OPIT5_19655	8.9e-42	163.0	COG0629@1|root,COG0629@2|Bacteria,46VZR@74201|Verrucomicrobia,3K80H@414999|Opitutae	414999|Opitutae	L	Single-stranded DNA-binding protein	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
CH3_k127_4665345_11	1396141.BATP01000023_gene664	4.698e-07	62.0	COG2931@1|root,COG3266@1|root,COG4733@1|root,COG4932@1|root,COG2931@2|Bacteria,COG3266@2|Bacteria,COG4733@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K20541	-	-	-	-	ko00000,ko02000	4.D.3.1.6	-	-	BcsB,DUF1499,Flg_new
CH3_k127_4665345_6	635013.TherJR_0182	1.566e-48	182.0	COG1694@1|root,COG3956@2|Bacteria,1TPK1@1239|Firmicutes,247XM@186801|Clostridia,2613S@186807|Peptococcaceae	186801|Clostridia	S	TIGRFAM MazG family protein	mazG	-	3.6.1.66	ko:K02428,ko:K02499	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG,TP_methylase
CH3_k127_4665345_4	452637.Oter_4153	1.582e-94	321.0	COG0263@1|root,COG0263@2|Bacteria,46SWM@74201|Verrucomicrobia,3K78E@414999|Opitutae	414999|Opitutae	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
CH3_k127_4665345_3	1121930.AQXG01000003_gene2719	5.616e-103	347.0	COG1363@1|root,COG1363@2|Bacteria,4NG97@976|Bacteroidetes,1INSP@117747|Sphingobacteriia	976|Bacteroidetes	G	peptidase M42	frvX	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
CH3_k127_4665345_5	272134.KB731324_gene6611	1.17e-66	258.0	COG0823@1|root,COG2373@1|root,COG2931@1|root,COG0823@2|Bacteria,COG2373@2|Bacteria,COG2931@2|Bacteria,1GQCK@1117|Cyanobacteria,1HI2W@1150|Oscillatoriales	1117|Cyanobacteria	Q	Domains in Na-Ca exchangers and integrin-beta4	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Calx-beta,DUF4347,HemolysinCabind,VCBS
CH3_k127_4665345_9	1303518.CCALI_02394	5.763e-10	70.0	COG4537@1|root,COG4537@2|Bacteria	2|Bacteria	U	Required for transformation and DNA binding	comGC	GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944	-	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	M00331,M00429	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
CH3_k127_4665345_10	326427.Cagg_1390	5.4e-09	63.0	COG1363@1|root,COG1363@2|Bacteria,2G5WS@200795|Chloroflexi,376QF@32061|Chloroflexia	32061|Chloroflexia	G	PFAM peptidase M18 aminopeptidase I	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
CH3_k127_4665345_0	595460.RRSWK_04532	1.15e-186	591.0	COG0673@1|root,COG0673@2|Bacteria,2IXPT@203682|Planctomycetes	203682|Planctomycetes	S	PFAM oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CH3_k127_4665345_1	661478.OP10G_3858	2.971e-136	443.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	yrbE	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CH3_k127_4665345_2	497964.CfE428DRAFT_3531	5.097e-114	378.0	COG1044@1|root,COG1044@2|Bacteria,46SAD@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,LpxD
CH3_k127_4665345_7	243090.RB2837	2.2e-21	96.0	COG1520@1|root,COG1520@2|Bacteria,2IXST@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CH3_k127_4825305_4	589865.DaAHT2_2268	4.547e-33	138.0	COG0457@1|root,COG0457@2|Bacteria,1NYJF@1224|Proteobacteria	1224|Proteobacteria	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_4825305_1	338969.Rfer_0253	2.019e-126	415.0	COG3005@1|root,COG3005@2|Bacteria,1R8V7@1224|Proteobacteria	1224|Proteobacteria	C	TIGRFAM cytochrome C family protein	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
CH3_k127_4825305_3	1121918.ARWE01000001_gene2300	6.691e-52	192.0	28PU4@1|root,2ZCF6@2|Bacteria,1RBK2@1224|Proteobacteria,43B3E@68525|delta/epsilon subdivisions,2X6H4@28221|Deltaproteobacteria,43U05@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_4825305_0	880073.Calab_1263	1.398e-170	552.0	COG3303@1|root,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
CH3_k127_4825305_2	243231.GSU3225	5.231e-61	226.0	COG3391@1|root,COG3391@2|Bacteria,1MYI5@1224|Proteobacteria,43AJ0@68525|delta/epsilon subdivisions,2X5Z8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_4825305_6	880073.Calab_1270	5.272e-23	115.0	2ENA5@1|root,33FXV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_4825305_7	880073.Calab_1269	1.555e-20	100.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
CH3_k127_4825305_5	338969.Rfer_0256	6.648e-32	127.0	COG3391@1|root,COG3391@2|Bacteria,1NT97@1224|Proteobacteria,2VNUX@28216|Betaproteobacteria	28216|Betaproteobacteria	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
CH3_k127_483524_4	388413.ALPR1_05710	3.927e-36	138.0	COG2936@1|root,COG2936@2|Bacteria,4NHGT@976|Bacteroidetes	976|Bacteroidetes	S	PFAM X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	3.4.14.11	ko:K01281	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PepX_C,Peptidase_S15
CH3_k127_483524_0	886293.Sinac_6948	1.855e-143	473.0	COG0665@1|root,COG0665@2|Bacteria,2J4YV@203682|Planctomycetes	203682|Planctomycetes	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
CH3_k127_483524_5	1349767.GJA_3077	4.479e-26	113.0	COG3507@1|root,COG3507@2|Bacteria,1R5VX@1224|Proteobacteria,2W0XY@28216|Betaproteobacteria	28216|Betaproteobacteria	G	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,RicinB_lectin_2
CH3_k127_483524_2	682795.AciX8_2232	2.665e-72	263.0	COG3507@1|root,COG3507@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_483524_6	999419.HMPREF1077_03358	3.245e-07	57.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,2FMMF@200643|Bacteroidia,22XE8@171551|Porphyromonadaceae	976|Bacteroidetes	G	Glycosyl hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_lyase,Glyco_hydro_92
CH3_k127_483524_1	344747.PM8797T_11556	9.182e-94	323.0	COG0673@1|root,COG0673@2|Bacteria,2IXA3@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CH3_k127_483524_3	1123242.JH636434_gene5340	1.605e-39	161.0	COG1413@1|root,COG1413@2|Bacteria,2IZE1@203682|Planctomycetes	203682|Planctomycetes	C	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
CH3_k127_4863129_8	760192.Halhy_3568	2.71e-21	98.0	COG1082@1|root,COG1082@2|Bacteria,4PJ9G@976|Bacteroidetes,1IZP5@117747|Sphingobacteriia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
CH3_k127_4863129_4	1185876.BN8_04770	6.285e-77	274.0	COG0673@1|root,COG0673@2|Bacteria,4NGHJ@976|Bacteroidetes,47K7H@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CH3_k127_4863129_10	661478.OP10G_4722	1.018e-09	73.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
CH3_k127_4863129_2	497964.CfE428DRAFT_1446	3.675e-123	436.0	COG2133@1|root,COG2133@2|Bacteria,46UME@74201|Verrucomicrobia	74201|Verrucomicrobia	G	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
CH3_k127_4863129_0	794903.OPIT5_28445	1.85e-182	580.0	COG0677@1|root,COG0677@2|Bacteria	2|Bacteria	M	UDP-N-acetyl-D-mannosamine dehydrogenase activity	wbpA	-	1.1.1.136	ko:K02474,ko:K13015	ko00520,map00520	-	R00421,R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
CH3_k127_4863129_1	1442599.JAAN01000005_gene1008	9.581e-150	480.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,1RPTA@1236|Gammaproteobacteria,1X46C@135614|Xanthomonadales	135614|Xanthomonadales	GM	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
CH3_k127_4863129_5	886293.Sinac_6555	1.067e-67	238.0	COG1131@1|root,COG1131@2|Bacteria,2IY18@203682|Planctomycetes	203682|Planctomycetes	V	ABC-type multidrug transport system ATPase	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CH3_k127_4863129_9	661478.OP10G_3704	3.472e-12	76.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	pilI	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
CH3_k127_4863129_6	497964.CfE428DRAFT_1467	6.096e-62	220.0	COG0131@1|root,COG0131@2|Bacteria,46SR2@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
CH3_k127_4863129_7	497964.CfE428DRAFT_0896	4.642e-43	164.0	COG1595@1|root,COG1595@2|Bacteria,46V3R@74201|Verrucomicrobia	74201|Verrucomicrobia	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
CH3_k127_4863129_3	497964.CfE428DRAFT_3932	1.471e-98	329.0	COG1530@1|root,COG1530@2|Bacteria,46S5S@74201|Verrucomicrobia	74201|Verrucomicrobia	J	TIGRFAM ribonuclease, Rne Rng family	cafA	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G
CH3_k127_4881920_4	886293.Sinac_5728	6.485e-72	248.0	COG2264@1|root,COG2264@2|Bacteria,2J3H0@203682|Planctomycetes	203682|Planctomycetes	J	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
CH3_k127_4881920_1	661478.OP10G_0808	2.091e-113	376.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
CH3_k127_4881920_3	497964.CfE428DRAFT_2254	2.825e-78	269.0	COG2197@1|root,COG2197@2|Bacteria,46TQM@74201|Verrucomicrobia	2|Bacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CH3_k127_4881920_0	1403819.BATR01000025_gene850	4.346e-119	403.0	COG4585@1|root,COG4585@2|Bacteria,46UGH@74201|Verrucomicrobia,2IVFF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
CH3_k127_4881920_6	1303518.CCALI_02394	1.044e-06	56.0	COG4537@1|root,COG4537@2|Bacteria	2|Bacteria	U	Required for transformation and DNA binding	comGC	GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944	-	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	M00331,M00429	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
CH3_k127_4881920_2	1042376.AFPK01000062_gene1333	1.934e-98	350.0	COG2503@1|root,COG2503@2|Bacteria,4PN2E@976|Bacteroidetes	976|Bacteroidetes	G	Alpha-1,2-mannosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_4881920_5	1237149.C900_04129	8.443e-14	85.0	COG2911@1|root,COG3469@1|root,COG3979@1|root,COG2911@2|Bacteria,COG3469@2|Bacteria,COG3979@2|Bacteria,4PKBR@976|Bacteroidetes,47Y17@768503|Cytophagia	976|Bacteroidetes	G	Carbohydrate binding domain	-	GO:0003674,GO:0003824,GO:0004553,GO:0004568,GO:0005575,GO:0005576,GO:0006022,GO:0006026,GO:0006030,GO:0006032,GO:0006040,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016798,GO:0017144,GO:0042737,GO:0043170,GO:0044237,GO:0044248,GO:0046348,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	CBM_5_12,CarboxypepD_reg,Glyco_hydro_18
CH3_k127_4904078_11	56780.SYN_02999	8.409e-21	93.0	COG0432@1|root,COG0432@2|Bacteria,1RA5G@1224|Proteobacteria,42QZ8@68525|delta/epsilon subdivisions,2WMV9@28221|Deltaproteobacteria,2MRJM@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
CH3_k127_4904078_13	489825.LYNGBM3L_21140	1.569e-17	95.0	COG1216@1|root,COG1216@2|Bacteria,1FZX3@1117|Cyanobacteria,1HA1F@1150|Oscillatoriales	2|Bacteria	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	GlcNAc,Glyco_tranf_2_3,Glycos_transf_2
CH3_k127_4904078_5	357808.RoseRS_2382	3.89e-62	229.0	COG1216@1|root,COG1216@2|Bacteria,2GB2A@200795|Chloroflexi,377SM@32061|Chloroflexia	32061|Chloroflexia	S	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CH3_k127_4904078_6	335541.Swol_2445	4.432e-41	160.0	COG2120@1|root,COG2120@2|Bacteria,1TUFP@1239|Firmicutes,25PKR@186801|Clostridia,42KY4@68298|Syntrophomonadaceae	186801|Clostridia	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
CH3_k127_4904078_4	251229.Chro_0879	1.244e-70	252.0	COG0438@1|root,COG0438@2|Bacteria,1G0Z5@1117|Cyanobacteria,3VKAC@52604|Pleurocapsales	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CH3_k127_4904078_3	489825.LYNGBM3L_21170	7.956e-136	442.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
CH3_k127_4904078_9	1449976.KALB_4422	2.152e-34	147.0	COG0500@1|root,COG0500@2|Bacteria,2INXQ@201174|Actinobacteria,4EDFK@85010|Pseudonocardiales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
CH3_k127_4904078_0	335543.Sfum_3551	2.9e-178	565.0	COG0438@1|root,COG0438@2|Bacteria,1RAGT@1224|Proteobacteria,42Y8X@68525|delta/epsilon subdivisions,2WU97@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_4904078_8	497964.CfE428DRAFT_2920	1.958e-38	152.0	COG0110@1|root,COG0110@2|Bacteria,46T6H@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
CH3_k127_4904078_7	1173026.Glo7428_0927	3.521e-39	154.0	COG0110@1|root,COG0110@2|Bacteria,1G9TY@1117|Cyanobacteria	1117|Cyanobacteria	T	PFAM Bacterial transferase hexapeptide (three repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
CH3_k127_4904078_2	335543.Sfum_3555	7.66e-138	463.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,43C63@68525|delta/epsilon subdivisions,2WTQK@28221|Deltaproteobacteria,2MSIN@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	PFAM ABC transporter, transmembrane region	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CH3_k127_4904078_1	489825.LYNGBM3L_21200	5.408e-138	462.0	COG1132@1|root,COG1132@2|Bacteria,1G1JY@1117|Cyanobacteria,1H7BU@1150|Oscillatoriales	1117|Cyanobacteria	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CH3_k127_4904078_12	649831.L083_3819	7.867e-19	101.0	COG3979@1|root,COG3979@2|Bacteria,2H72H@201174|Actinobacteria,4DJJD@85008|Micromonosporales	201174|Actinobacteria	S	chitinase	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_4904078_14	313606.M23134_01193	5.16e-13	82.0	COG3469@1|root,COG3979@1|root,COG3469@2|Bacteria,COG3979@2|Bacteria,4PKBR@976|Bacteroidetes,47Y17@768503|Cytophagia	976|Bacteroidetes	G	Carbohydrate binding domain	-	GO:0003674,GO:0003824,GO:0004553,GO:0004568,GO:0005575,GO:0005576,GO:0006022,GO:0006026,GO:0006030,GO:0006032,GO:0006040,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016798,GO:0017144,GO:0042737,GO:0043170,GO:0044237,GO:0044248,GO:0046348,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	CBM_5_12,CarboxypepD_reg,Glyco_hydro_18
CH3_k127_4904078_10	794903.OPIT5_14550	8.647e-28	121.0	COG2165@1|root,COG2165@2|Bacteria,46Y3B@74201|Verrucomicrobia,3K8VC@414999|Opitutae	414999|Opitutae	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
CH3_k127_4917276_0	671143.DAMO_0532	1.932e-308	977.0	COG0085@1|root,COG0085@2|Bacteria,2NNM9@2323|unclassified Bacteria	2|Bacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03043,ko:K13797	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
CH3_k127_4917276_1	1121354.AQUV01000002_gene956	1.343e-18	87.0	COG0222@1|root,COG0222@2|Bacteria,2IKNW@201174|Actinobacteria,22N5E@1653|Corynebacteriaceae	201174|Actinobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
CH3_k127_493873_1	497964.CfE428DRAFT_4013	9.882e-162	522.0	COG0513@1|root,COG0513@2|Bacteria,46TUA@74201|Verrucomicrobia	74201|Verrucomicrobia	L	DEAD DEAH box helicase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
CH3_k127_493873_0	1303518.CCALI_00634	0.0	1064.0	28K2K@1|root,2Z9RX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_493873_2	237368.SCABRO_00783	4.899e-52	192.0	28KNW@1|root,2ZA74@2|Bacteria	2|Bacteria	L	Restriction endonuclease XhoI	-	-	3.1.21.4	ko:K01155	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	XhoI
CH3_k127_493873_4	195250.CM001776_gene223	2.625e-11	72.0	COG1487@1|root,COG1487@2|Bacteria,1G6RD@1117|Cyanobacteria,1H1XR@1129|Synechococcus	1117|Cyanobacteria	S	PIN domain	-	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
CH3_k127_493873_3	909663.KI867150_gene85	4.505e-19	90.0	COG0863@1|root,COG0863@2|Bacteria,1R7RV@1224|Proteobacteria,42NFT@68525|delta/epsilon subdivisions,2WJMQ@28221|Deltaproteobacteria,2MRAU@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	DNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase
CH3_k127_4938752_2	497964.CfE428DRAFT_1797	1.454e-75	261.0	COG0008@1|root,COG0008@2|Bacteria,46SJ3@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
CH3_k127_4938752_3	1227349.C170_16540	1.128e-07	61.0	2AKTD@1|root,31BKE@2|Bacteria,1VPBC@1239|Firmicutes,4HSWR@91061|Bacilli,272ZY@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_4938752_0	1121468.AUBR01000021_gene2825	1.08e-304	953.0	COG1449@1|root,COG1449@2|Bacteria,1UVAN@1239|Firmicutes,24B0Y@186801|Clostridia,42HS1@68295|Thermoanaerobacterales	186801|Clostridia	G	Domain of unknown function (DUF3536)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3536,Glyco_hydro_57
CH3_k127_4938752_1	1379270.AUXF01000001_gene2442	2.201e-199	632.0	COG0405@1|root,COG0405@2|Bacteria	2|Bacteria	E	Gamma-glutamyltransferase	ggt_2	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
CH3_k127_4957878_0	1173028.ANKO01000141_gene601	8.651e-81	309.0	COG0642@1|root,COG2199@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria,1G13T@1117|Cyanobacteria,1H77Q@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
CH3_k127_4984328_2	595460.RRSWK_04460	3.542e-47	181.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
CH3_k127_4984328_1	1123242.JH636436_gene23	1.562e-85	304.0	COG1335@1|root,COG1413@1|root,COG2010@1|root,COG2133@1|root,COG3828@1|root,COG1335@2|Bacteria,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,COG3828@2|Bacteria,2IX4V@203682|Planctomycetes	203682|Planctomycetes	C	COG2133 Glucose sorbosone dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
CH3_k127_4984328_0	1123242.JH636434_gene4791	1.78e-93	327.0	COG0673@1|root,COG0673@2|Bacteria,2IXRR@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CH3_k127_4984328_4	1279038.KB907339_gene1243	0.0002746	48.0	COG2114@1|root,COG2114@2|Bacteria,1NAJG@1224|Proteobacteria,2TSVT@28211|Alphaproteobacteria,2JUSX@204441|Rhodospirillales	204441|Rhodospirillales	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
CH3_k127_4988670_0	1121015.N789_02215	8.865e-109	360.0	COG0652@1|root,COG0652@2|Bacteria,1QCY4@1224|Proteobacteria,1RRUQ@1236|Gammaproteobacteria,1XCF4@135614|Xanthomonadales	135614|Xanthomonadales	M	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	Pro_isomerase
CH3_k127_4988670_1	515635.Dtur_0653	1.665e-51	204.0	arCOG07336@1|root,2Z8ST@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_4988670_3	1121904.ARBP01000052_gene3650	1.875e-27	125.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	AXE1,Hydrolase_4
CH3_k127_4988670_2	880070.Cycma_2352	7.905e-41	172.0	COG3669@1|root,COG3669@2|Bacteria,4NHRG@976|Bacteroidetes,47TRP@768503|Cytophagia	976|Bacteroidetes	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos
CH3_k127_4992081_4	497964.CfE428DRAFT_0064	1.537e-54	200.0	COG1595@1|root,COG1595@2|Bacteria,46VJP@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
CH3_k127_4992081_2	1229909.NSED_00255	1.166e-67	231.0	COG0432@1|root,arCOG04214@2157|Archaea,41T31@651137|Thaumarchaeota	651137|Thaumarchaeota	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
CH3_k127_4992081_6	640081.Dsui_2056	7.046e-18	90.0	COG1403@1|root,COG1403@2|Bacteria,1RIEZ@1224|Proteobacteria,2VTF6@28216|Betaproteobacteria,2KWR0@206389|Rhodocyclales	206389|Rhodocyclales	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
CH3_k127_4992081_7	1303518.CCALI_00913	7.607e-14	81.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
CH3_k127_4992081_8	1463825.JNXC01000053_gene31	6.221e-05	53.0	COG3507@1|root,COG3507@2|Bacteria,2I911@201174|Actinobacteria,4E0PM@85010|Pseudonocardiales	201174|Actinobacteria	G	Cellulose Binding Domain Type IV	-	-	3.2.1.55	ko:K15921	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	CBM6,GH43	-	CBM_4_9,CBM_6,Glyco_hydro_43
CH3_k127_4992081_1	1268240.ATFI01000008_gene2201	1.698e-83	295.0	COG2006@1|root,COG2006@2|Bacteria,4P0ZM@976|Bacteroidetes,2FR0W@200643|Bacteroidia,4APQE@815|Bacteroidaceae	976|Bacteroidetes	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
CH3_k127_4992081_5	331678.Cphamn1_0748	3.839e-21	93.0	COG0286@1|root,COG0286@2|Bacteria,1FERX@1090|Chlorobi	1090|Chlorobi	H	N-6 DNA Methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
CH3_k127_4992081_3	365046.Rta_00040	6.006e-67	230.0	COG0286@1|root,COG0286@2|Bacteria,1NN38@1224|Proteobacteria,2VNIU@28216|Betaproteobacteria,4AGSN@80864|Comamonadaceae	28216|Betaproteobacteria	V	N-6 DNA Methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
CH3_k127_4992081_0	518766.Rmar_1740	1.289e-106	362.0	COG0673@1|root,COG0673@2|Bacteria,4NEN5@976|Bacteroidetes,1FK20@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CH3_k127_4993308_3	1123242.JH636434_gene5139	1.253e-64	224.0	COG2025@1|root,COG2025@2|Bacteria,2J3Y1@203682|Planctomycetes	203682|Planctomycetes	C	Electron transfer flavoprotein domain	-	-	-	-	-	-	-	-	-	-	-	-	ETF,ETF_alpha
CH3_k127_4993308_0	1123242.JH636434_gene5138	5.277e-182	592.0	COG0247@1|root,COG0247@2|Bacteria	2|Bacteria	C	lactate metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	CCG,ETF,Fer4_10,Fer4_8,Fer4_9,Nitrate_red_gam
CH3_k127_4993308_2	1123242.JH636434_gene5137	4.146e-111	385.0	COG0247@1|root,COG0247@2|Bacteria	2|Bacteria	C	lactate metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
CH3_k127_4993308_4	1303518.CCALI_02658	1.44e-10	71.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
CH3_k127_4993308_1	1396418.BATQ01000058_gene90	6.173e-122	395.0	COG0684@1|root,COG0684@2|Bacteria,46SB3@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
CH3_k127_4996560_2	880073.Calab_3105	3.371e-212	674.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	ampG	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	BT1,MFS_1
CH3_k127_4996560_16	28072.Nos7524_1372	1.17e-64	254.0	COG1572@1|root,COG2931@1|root,COG3209@1|root,COG3210@1|root,COG3291@1|root,COG3386@1|root,COG3391@1|root,COG1572@2|Bacteria,COG2931@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,COG3391@2|Bacteria,1G1WI@1117|Cyanobacteria	1117|Cyanobacteria	Q	PFAM Bacterial pre-peptidase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Cadherin,Calx-beta,PPC
CH3_k127_4996560_27	1121887.AUDK01000004_gene431	6.105e-06	61.0	COG2911@1|root,COG3210@1|root,COG3533@1|root,COG4625@1|root,COG4733@1|root,COG2911@2|Bacteria,COG3210@2|Bacteria,COG3533@2|Bacteria,COG4625@2|Bacteria,COG4733@2|Bacteria,4PPKP@976|Bacteroidetes,1IKQ3@117743|Flavobacteriia,2P0T3@237|Flavobacterium	976|Bacteroidetes	U	Alginate lyase	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Laminin_G_3
CH3_k127_4996560_11	349741.Amuc_0030	1.631e-119	396.0	COG2334@1|root,COG2334@2|Bacteria,46TIS@74201|Verrucomicrobia,2IVEV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
CH3_k127_4996560_4	452637.Oter_0886	8.855e-139	449.0	COG0468@1|root,COG0468@2|Bacteria,46SIZ@74201|Verrucomicrobia,3K737@414999|Opitutae	414999|Opitutae	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
CH3_k127_4996560_20	118005.AWNK01000005_gene1565	2.476e-46	177.0	COG0290@1|root,COG0290@2|Bacteria	2|Bacteria	J	translation initiation factor activity	infC	GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
CH3_k127_4996560_3	1396418.BATQ01000079_gene806	4.782e-178	567.0	COG0520@1|root,COG0520@2|Bacteria,46S58@74201|Verrucomicrobia,2IU2B@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
CH3_k127_4996560_18	105559.Nwat_0649	7.133e-58	207.0	COG2151@1|root,COG2151@2|Bacteria,1MZ9Y@1224|Proteobacteria,1S36X@1236|Gammaproteobacteria,1WY7B@135613|Chromatiales	135613|Chromatiales	S	TIGRFAM FeS assembly SUF system protein SufT	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
CH3_k127_4996560_19	1042209.HK44_007325	1.478e-49	180.0	COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,1S3P1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters	nifU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
CH3_k127_4996560_6	794903.OPIT5_30480	5.259e-134	439.0	COG0501@1|root,COG0501@2|Bacteria,46TVV@74201|Verrucomicrobia,3K72R@414999|Opitutae	414999|Opitutae	O	Peptidase M48	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
CH3_k127_4996560_23	497964.CfE428DRAFT_5124	5.105e-25	109.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,LytTR,PAS,PAS_3,PAS_9,Response_reg,dCache_1
CH3_k127_4996560_26	497964.CfE428DRAFT_1483	1.495e-06	49.0	COG0436@1|root,COG0436@2|Bacteria,46TMR@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate	-	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CH3_k127_4996560_17	497964.CfE428DRAFT_5394	3.474e-60	230.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	SGL
CH3_k127_4996560_1	497964.CfE428DRAFT_1483	1.928e-212	666.0	COG0436@1|root,COG0436@2|Bacteria,46TMR@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate	-	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CH3_k127_4996560_14	215803.DB30_6514	6.18e-75	265.0	COG4948@1|root,COG4948@2|Bacteria,1MW76@1224|Proteobacteria,42Q93@68525|delta/epsilon subdivisions,2WKAA@28221|Deltaproteobacteria,2YYHJ@29|Myxococcales	28221|Deltaproteobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
CH3_k127_4996560_0	671143.DAMO_0980	1.141e-275	863.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2NP1J@2323|unclassified Bacteria	2|Bacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_13,Fer4_6,PFOR_II,POR,POR_N,TPP_enzyme_C
CH3_k127_4996560_9	234267.Acid_4784	1.3e-127	424.0	COG0591@1|root,COG0591@2|Bacteria,3Y419@57723|Acidobacteria	57723|Acidobacteria	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
CH3_k127_4996560_5	1403819.BATR01000098_gene3267	2.176e-135	439.0	COG0042@1|root,COG0042@2|Bacteria,46TSS@74201|Verrucomicrobia,2ITU4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	ko:K05541	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
CH3_k127_4996560_7	452637.Oter_1656	7.695e-134	430.0	COG2013@1|root,COG2013@2|Bacteria,46SY6@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
CH3_k127_4996560_15	661478.OP10G_3898	4.019e-70	250.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456,ko:K02650	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10,T2SSG
CH3_k127_4996560_21	1210884.HG799462_gene8039	1.882e-44	173.0	COG0845@1|root,COG0845@2|Bacteria,2IYMS@203682|Planctomycetes	203682|Planctomycetes	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
CH3_k127_4996560_29	2423.NA23_0209590	0.0002641	51.0	COG1413@1|root,COG1413@2|Bacteria,2GDN4@200918|Thermotogae	200918|Thermotogae	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
CH3_k127_4996560_13	1379270.AUXF01000004_gene3002	1.471e-109	374.0	COG2986@1|root,COG2986@2|Bacteria,1ZTEG@142182|Gemmatimonadetes	2|Bacteria	E	Aromatic amino acid lyase	-	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006570,GO:0006572,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009072,GO:0009074,GO:0009698,GO:0009699,GO:0009987,GO:0016043,GO:0016054,GO:0016829,GO:0016840,GO:0016841,GO:0019438,GO:0019439,GO:0019748,GO:0019752,GO:0022607,GO:0042802,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044550,GO:0046395,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0052883,GO:0065003,GO:0071704,GO:0071840,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901605,GO:1901606	4.3.1.23,4.3.1.3	ko:K01745,ko:K10774	ko00340,ko00350,ko01100,map00340,map00350,map01100	M00045	R00737,R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
CH3_k127_4996560_10	153721.MYP_192	3.266e-127	420.0	COG0644@1|root,COG0644@2|Bacteria,4NEI6@976|Bacteroidetes,47MPG@768503|Cytophagia	976|Bacteroidetes	C	Tryptophan halogenase	fixC	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
CH3_k127_4996560_8	485918.Cpin_1862	1.725e-128	422.0	COG0500@1|root,COG2226@2|Bacteria,4NGN8@976|Bacteroidetes,1IUWM@117747|Sphingobacteriia	976|Bacteroidetes	Q	O-methyltransferase	crtF	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_2
CH3_k127_4996560_12	1116472.MGMO_20c00270	6.257e-114	382.0	COG0644@1|root,COG0644@2|Bacteria,1MZVI@1224|Proteobacteria,1RMNS@1236|Gammaproteobacteria,1XDKP@135618|Methylococcales	1236|Gammaproteobacteria	C	Tryptophan halogenase	pltM	-	1.14.19.49	ko:K14257	ko00253,ko00404,ko01057,ko01130,map00253,map00404,map01057,map01130	M00790,M00823	R05456,R11106,R11478	RC00949	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_halogenase
CH3_k127_4996560_22	671143.DAMO_0701	1.66e-36	150.0	COG0500@1|root,COG2226@2|Bacteria,2NRU8@2323|unclassified Bacteria	2|Bacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
CH3_k127_4996560_28	998674.ATTE01000001_gene3175	7.068e-05	55.0	COG1649@1|root,COG4932@1|root,COG1649@2|Bacteria,COG4932@2|Bacteria,1NP4V@1224|Proteobacteria	1224|Proteobacteria	G	Hypothetical glycosyl hydrolase 6	-	-	-	-	-	-	-	-	-	-	-	-	GHL6,Glyco_hydro_42M
CH3_k127_4996560_24	160799.PBOR_01905	3.048e-15	88.0	COG1409@1|root,COG3250@1|root,COG1409@2|Bacteria,COG3250@2|Bacteria,1V0BS@1239|Firmicutes,4HCTY@91061|Bacilli,26TEF@186822|Paenibacillaceae	91061|Bacilli	G	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,F5_F8_type_C,Metallophos,PA14,Pur_ac_phosph_N,fn3
CH3_k127_5020529_10	485917.Phep_4007	1.021e-09	72.0	28KZC@1|root,2ZAEP@2|Bacteria,4NITB@976|Bacteroidetes,1IVQJ@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_5020529_3	886293.Sinac_7535	7.789e-104	352.0	COG5434@1|root,COG5434@2|Bacteria,2IX4K@203682|Planctomycetes	2|Bacteria	M	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Pectate_lyase_3
CH3_k127_5020529_7	390989.JOEG01000007_gene674	6.588e-53	206.0	COG1572@1|root,COG1572@2|Bacteria,2HWQ1@201174|Actinobacteria,4DJWH@85008|Micromonosporales	201174|Actinobacteria	N	Domain of unknown function (DUF4091)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4091
CH3_k127_5020529_5	1123242.JH636435_gene769	3.376e-78	275.0	2DBNR@1|root,2ZA54@2|Bacteria,2IYX9@203682|Planctomycetes	203682|Planctomycetes	S	Methane oxygenase PmoA	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
CH3_k127_5020529_2	861299.J421_5653	9.316e-114	389.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CH3_k127_5020529_1	1123242.JH636434_gene3154	4.862e-126	413.0	COG2159@1|root,COG2159@2|Bacteria,2J3RZ@203682|Planctomycetes	203682|Planctomycetes	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CH3_k127_5020529_0	1123242.JH636435_gene772	1.965e-173	554.0	COG0477@1|root,COG2814@2|Bacteria,2J4VW@203682|Planctomycetes	1123242.JH636435_gene772|-	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_5020529_6	234267.Acid_7405	9.072e-61	221.0	COG2084@1|root,COG2084@2|Bacteria	2|Bacteria	I	phosphogluconate dehydrogenase (decarboxylating) activity	mmsB	-	1.1.1.31,1.1.1.60	ko:K00020,ko:K00042	ko00280,ko00630,ko01100,map00280,map00630,map01100	-	R01745,R01747,R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
CH3_k127_5020529_4	616991.JPOO01000001_gene2853	1.112e-88	306.0	COG4409@1|root,COG4409@2|Bacteria,4PAPR@976|Bacteroidetes,1IF7B@117743|Flavobacteriia,23HKK@178469|Arenibacter	976|Bacteroidetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
CH3_k127_5020529_9	886293.Sinac_0556	1.849e-16	89.0	COG2165@1|root,COG2165@2|Bacteria,2IZ3B@203682|Planctomycetes	203682|Planctomycetes	NU	Protein of unknown function (DUF1559)	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CH3_k127_5020529_8	1403819.BATR01000069_gene2031	2.087e-23	116.0	COG1470@1|root,COG1749@1|root,COG3291@1|root,COG3506@1|root,COG3533@1|root,COG1470@2|Bacteria,COG1749@2|Bacteria,COG3291@2|Bacteria,COG3506@2|Bacteria,COG3533@2|Bacteria,46SQ1@74201|Verrucomicrobia,2IV3A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	N	Erythromycin esterase	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_5026670_0	661478.OP10G_1031	1.699e-260	827.0	COG1621@1|root,COG4354@1|root,COG1621@2|Bacteria,COG4354@2|Bacteria	2|Bacteria	G	intracellular protein transport	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2,DUF608,Glyco_hydr_116N,VCBS
CH3_k127_5026670_1	485913.Krac_11430	8.193e-134	448.0	COG2936@1|root,COG2936@2|Bacteria,2G85Q@200795|Chloroflexi	2|Bacteria	S	PFAM X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
CH3_k127_5026670_2	861299.J421_1735	7.471e-67	248.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CH3_k127_5026670_3	886293.Sinac_3469	1.766e-60	229.0	COG1506@1|root,COG1506@2|Bacteria,2IXED@203682|Planctomycetes	203682|Planctomycetes	E	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
CH3_k127_5030758_2	84531.JMTZ01000116_gene1140	5.309e-12	80.0	COG3210@1|root,COG3210@2|Bacteria,1QUUN@1224|Proteobacteria	1224|Proteobacteria	U	Outer membrane autotransporter	-	-	-	ko:K19231	-	-	-	-	ko00000,ko02000	1.B.12	-	-	Big_3_3,ESPR,PATR
CH3_k127_5030758_1	356851.JOAN01000024_gene4479	3.078e-18	100.0	COG1501@1|root,COG3669@1|root,COG1501@2|Bacteria,COG3669@2|Bacteria,2I9R1@201174|Actinobacteria,4DH6V@85008|Micromonosporales	201174|Actinobacteria	G	Carbohydrate binding domain X2	-	-	-	-	-	-	-	-	-	-	-	-	CBM_X2,Melibiase_2
CH3_k127_5030758_0	1206731.BAGB01000139_gene7783	2.312e-52	212.0	COG3669@1|root,COG3669@2|Bacteria	2|Bacteria	G	Alpha-L-fucosidase	-	-	-	-	-	-	-	-	-	-	-	-	Alpha_L_fucos
CH3_k127_5037733_0	439235.Dalk_2979	1.518e-51	191.0	COG0420@1|root,COG0420@2|Bacteria	2|Bacteria	L	3'-5' exonuclease activity	-	-	3.1.1.53	ko:K03547,ko:K05970	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Metallophos,Metallophos_2
CH3_k127_5037733_1	1125701.HMPREF1221_01616	5.673e-41	171.0	COG2407@1|root,COG2407@2|Bacteria	2|Bacteria	G	Converts the aldose L-fucose into the corresponding ketose L-fuculose	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_5037733_2	382464.ABSI01000005_gene1296	1.862e-11	70.0	COG0457@1|root,COG0515@1|root,COG3291@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG3291@2|Bacteria,46UMT@74201|Verrucomicrobia,2IVH7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,PEGA,PG_binding_1,Pkinase
CH3_k127_5096979_2	595460.RRSWK_06785	2.046e-48	199.0	COG0515@1|root,COG0515@2|Bacteria,2J0PH@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CH3_k127_5096979_1	497964.CfE428DRAFT_4864	5.234e-66	238.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_5096979_0	1305732.JAGG01000001_gene400	2.457e-74	256.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4FN30@85023|Microbacteriaceae	201174|Actinobacteria	C	Aldehyde dehydrogenase family	gabD	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CH3_k127_5097814_5	1267535.KB906767_gene3386	1.92e-32	135.0	COG0673@1|root,COG0673@2|Bacteria,3Y39X@57723|Acidobacteria	57723|Acidobacteria	S	PFAM oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CH3_k127_5097814_4	247490.KSU1_D0514	1.318e-41	179.0	COG3055@1|root,COG3204@1|root,COG3055@2|Bacteria,COG3204@2|Bacteria	2|Bacteria	L	pilus organization	-	-	-	ko:K02674,ko:K07004	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Big_5,Exo_endo_phos,He_PIG,HemolysinCabind,LTD,Laminin_G_3,Malectin,PA14
CH3_k127_5097814_0	1396141.BATP01000030_gene3715	1.747e-279	934.0	COG2010@1|root,COG2312@1|root,COG5337@1|root,COG5563@1|root,COG2010@2|Bacteria,COG2312@2|Bacteria,COG5337@2|Bacteria,COG5563@2|Bacteria,46XD5@74201|Verrucomicrobia,2IVHX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Fn3_assoc,LTD
CH3_k127_5097814_3	595460.RRSWK_04460	5.051e-120	391.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
CH3_k127_5097814_6	595460.RRSWK_06357	8.78e-07	60.0	COG3828@1|root,COG3828@2|Bacteria	2|Bacteria	N	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,PmoA
CH3_k127_5097814_1	886293.Sinac_5476	6.096e-209	680.0	COG0153@1|root,COG1207@1|root,COG0153@2|Bacteria,COG1207@2|Bacteria	2|Bacteria	M	glucosamine-1-phosphate N-acetyltransferase activity	galK	-	2.3.1.209,2.7.1.157,2.7.1.6	ko:K00849,ko:K02406,ko:K18674,ko:K21379	ko00052,ko00520,ko01100,ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map00052,map00520,map01100,map02020,map02040,map04621,map04626,map05132,map05134	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko02035,ko04147	-	-	-	DUF4954,GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg,Hexapep
CH3_k127_5097814_2	1288963.ADIS_1775	3.196e-177	567.0	COG1621@1|root,COG1621@2|Bacteria,4P0AM@976|Bacteroidetes	976|Bacteroidetes	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_5097814_7	1185876.BN8_05301	1.966e-05	52.0	COG3693@1|root,COG3693@2|Bacteria,4NE5Z@976|Bacteroidetes,47Q9Y@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolase family 10	xynT	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	CBM_4_9,Glyco_hydro_10
CH3_k127_510567_1	1121920.AUAU01000024_gene2386	1.724e-116	381.0	COG0755@1|root,COG0755@2|Bacteria	2|Bacteria	O	cytochrome complex assembly	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
CH3_k127_510567_0	243231.GSU2888	8.235e-162	529.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,42ZYI@68525|delta/epsilon subdivisions,2WVGV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,Radical_SAM
CH3_k127_510567_2	1121920.AUAU01000024_gene2381	7.959e-63	242.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
CH3_k127_510567_4	1189620.AJXL01000074_gene3244	1.442e-07	65.0	COG1345@1|root,COG1361@1|root,COG1520@1|root,COG3291@1|root,COG1345@2|Bacteria,COG1361@2|Bacteria,COG1520@2|Bacteria,COG3291@2|Bacteria,4NEZF@976|Bacteroidetes,1HZ6F@117743|Flavobacteriia,2NSYB@237|Flavobacterium	976|Bacteroidetes	N	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_5113127_5	1521187.JPIM01000120_gene290	1.36e-05	56.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	lspI	-	-	ko:K02246,ko:K02457,ko:K02458	ko03070,ko05111,map03070,map05111	M00331,M00429	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSI
CH3_k127_5113127_4	1403313.AXBR01000024_gene4802	7.703e-08	64.0	COG1621@1|root,COG1621@2|Bacteria,1TPAE@1239|Firmicutes,4H9Y7@91061|Bacilli,1ZCBA@1386|Bacillus	91061|Bacilli	G	invertase	-	-	3.2.1.80	ko:K03332	ko00051,map00051	-	R00879	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_32C,Glyco_hydro_32N,RicinB_lectin_2
CH3_k127_5113127_3	794903.OPIT5_04765	5.388e-10	70.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
CH3_k127_5113127_2	234267.Acid_6615	5.591e-18	95.0	28KX8@1|root,2ZAD8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_5113127_0	1379698.RBG1_1C00001G1835	5.584e-27	118.0	COG1520@1|root,COG1520@2|Bacteria,2NQ51@2323|unclassified Bacteria	2|Bacteria	O	NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,PQQ_2,SBBP
CH3_k127_5128113_1	1550073.JROH01000021_gene157	1.412e-79	273.0	COG3250@1|root,COG3250@2|Bacteria,1PMI2@1224|Proteobacteria,2V04M@28211|Alphaproteobacteria,2K8HX@204457|Sphingomonadales	204457|Sphingomonadales	G	Glycosyl hydrolases family 2, sugar binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2_N
CH3_k127_5128113_0	518766.Rmar_0491	4.717e-128	427.0	COG4146@1|root,COG4146@2|Bacteria,4NE9S@976|Bacteroidetes,1FJX9@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
CH3_k127_5128113_2	401526.TcarDRAFT_1824	1.426e-61	236.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,4H2CW@909932|Negativicutes	909932|Negativicutes	L	DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
CH3_k127_5144121_1	28444.JODQ01000006_gene10	0.0001259	56.0	COG2931@1|root,COG3204@1|root,COG2931@2|Bacteria,COG3204@2|Bacteria,2I94U@201174|Actinobacteria	201174|Actinobacteria	K	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	LTD,Phytase-like
CH3_k127_5144121_0	1396141.BATP01000040_gene2165	5.06e-165	558.0	COG2312@1|root,COG4870@1|root,COG5337@1|root,COG2312@2|Bacteria,COG4870@2|Bacteria,COG5337@2|Bacteria,46XSC@74201|Verrucomicrobia,2IWGQ@203494|Verrucomicrobiae	2|Bacteria	M	CotH kinase protein	cotH	-	-	ko:K06330	-	-	-	-	ko00000	-	-	-	CotH,Erythro_esteras,LTD,Peptidase_C1
CH3_k127_5152863_1	1121957.ATVL01000008_gene4136	7.576e-75	264.0	COG1446@1|root,COG1446@2|Bacteria,4NE3D@976|Bacteroidetes,47JDT@768503|Cytophagia	976|Bacteroidetes	E	PFAM peptidase T2 asparaginase 2	aspG	GO:0005575,GO:0005623,GO:0042597,GO:0044464	3.4.19.5,3.5.1.26	ko:K01444,ko:K13051	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Asparaginase_2
CH3_k127_5152863_3	1123276.KB893290_gene5291	1.079e-14	78.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,4NK8Q@976|Bacteroidetes,47KVN@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
CH3_k127_5152863_0	138119.DSY0252	2.19e-110	372.0	COG2204@1|root,COG2204@2|Bacteria,1VSKG@1239|Firmicutes,24ZP4@186801|Clostridia,2646G@186807|Peptococcaceae	186801|Clostridia	T	Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CH3_k127_5152863_2	913865.DOT_4639	1.33e-67	252.0	COG0243@1|root,COG0243@2|Bacteria,1TPZG@1239|Firmicutes,247JV@186801|Clostridia,2605J@186807|Peptococcaceae	186801|Clostridia	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.8.5.5,1.8.5.6	ko:K08352,ko:K21307	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R10149,R11487	RC00168,RC02823	ko00000,ko00001,ko01000,ko02000	5.A.3.5	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
CH3_k127_5153150_0	1140.Synpcc7942_0722	4.492e-45	179.0	28JXH@1|root,2ZA3Z@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	RecT
CH3_k127_5155091_0	316274.Haur_4056	7.529e-07	52.0	COG1520@1|root,COG3391@1|root,COG1520@2|Bacteria,COG3391@2|Bacteria,2G9GE@200795|Chloroflexi,3774I@32061|Chloroflexia	32061|Chloroflexia	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_5155091_2	395495.Lcho_1378	5.201e-06	55.0	COG1749@1|root,COG2730@1|root,COG1749@2|Bacteria,COG2730@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	flgK	-	-	ko:K02388,ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	DUF4082,Flg_bb_rod,Flg_bbr_C
CH3_k127_5155091_3	587753.EY04_17190	0.0009359	48.0	2D485@1|root,32TGJ@2|Bacteria,1PBDU@1224|Proteobacteria,1S02H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_5161430_2	452637.Oter_1389	3.535e-155	533.0	COG0515@1|root,COG0515@2|Bacteria,46VB0@74201|Verrucomicrobia,3K8AK@414999|Opitutae	414999|Opitutae	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CH3_k127_5161430_6	1123508.JH636439_gene990	1.168e-54	197.0	COG1595@1|root,COG1595@2|Bacteria,2IZ8A@203682|Planctomycetes	203682|Planctomycetes	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
CH3_k127_5161430_9	42256.RradSPS_0086	3.354e-22	104.0	COG0681@1|root,COG0681@2|Bacteria,2GIYN@201174|Actinobacteria,4CQK4@84995|Rubrobacteria	84995|Rubrobacteria	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
CH3_k127_5161430_0	1396141.BATP01000039_gene1469	7.065e-187	595.0	COG5337@1|root,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	-	-	-	-	-	-	-	-	-	-	-	-	CotH
CH3_k127_5161430_7	530564.Psta_3452	9.803e-41	160.0	COG5036@1|root,COG5036@2|Bacteria,2J00S@203682|Planctomycetes	203682|Planctomycetes	P	VTC domain	-	-	-	-	-	-	-	-	-	-	-	-	VTC
CH3_k127_5161430_8	521674.Plim_3170	4.047e-30	125.0	COG1285@1|root,COG1285@2|Bacteria,2IZY6@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF4956)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
CH3_k127_5161430_10	530564.Psta_3453	1.334e-14	76.0	COG1285@1|root,COG1285@2|Bacteria,2IZY6@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF4956)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
CH3_k127_5161430_1	1168034.FH5T_18125	4.823e-173	554.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CH3_k127_5161430_11	204669.Acid345_0203	1.284e-08	57.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,3Y3IF@57723|Acidobacteria,2JIPC@204432|Acidobacteriia	204432|Acidobacteriia	HP	PFAM UBA THIF-type NAD FAD binding	-	-	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF,ThiS
CH3_k127_5161430_4	272134.KB731324_gene3229	5.359e-108	367.0	COG5002@1|root,COG5002@2|Bacteria,1GQDS@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
CH3_k127_5161430_5	382464.ABSI01000007_gene4118	1.177e-86	291.0	COG0745@1|root,COG0745@2|Bacteria,46TFB@74201|Verrucomicrobia,2IUEX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CH3_k127_5161430_3	593750.Metfor_1047	3.155e-123	415.0	arCOG09580@1|root,arCOG09580@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_516319_4	886293.Sinac_6391	7.477e-166	535.0	COG2366@1|root,COG2366@2|Bacteria,2J08A@203682|Planctomycetes	203682|Planctomycetes	S	Penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
CH3_k127_516319_17	452637.Oter_2422	1.174e-69	240.0	COG1595@1|root,COG1595@2|Bacteria,46VAN@74201|Verrucomicrobia	74201|Verrucomicrobia	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
CH3_k127_516319_21	1192034.CAP_4540	4.138e-46	192.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1MVEU@1224|Proteobacteria,438BB@68525|delta/epsilon subdivisions,2X3KN@28221|Deltaproteobacteria,2YWFV@29|Myxococcales	1224|Proteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K08282,ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_10,TPR_12
CH3_k127_516319_32	1120966.AUBU01000002_gene1998	1.124e-05	55.0	2BXUX@1|root,32R23@2|Bacteria,4NR4Y@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_516319_8	530564.Psta_1668	1.842e-128	426.0	COG1520@1|root,COG1520@2|Bacteria,2IY7A@203682|Planctomycetes	203682|Planctomycetes	S	COG1520 FOG WD40-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
CH3_k127_516319_18	575540.Isop_0616	2.65e-68	247.0	COG0526@1|root,COG0526@2|Bacteria,2J06Z@203682|Planctomycetes	203682|Planctomycetes	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Redoxin
CH3_k127_516319_2	452637.Oter_1374	2.038e-234	736.0	COG3534@1|root,COG3534@2|Bacteria,46TJZ@74201|Verrucomicrobia,3K9HJ@414999|Opitutae	414999|Opitutae	G	alpha-L-arabinofuranosidase domain protein	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
CH3_k127_516319_9	1122917.KB899665_gene3972	5.417e-116	384.0	COG1052@1|root,COG1052@2|Bacteria,1TPCX@1239|Firmicutes,4HASY@91061|Bacilli,26W35@186822|Paenibacillaceae	91061|Bacilli	CH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	-	-	1.1.1.26	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	-	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
CH3_k127_516319_0	452637.Oter_3359	3.774e-315	988.0	COG1643@1|root,COG1643@2|Bacteria,46TMT@74201|Verrucomicrobia,3K7J2@414999|Opitutae	414999|Opitutae	L	ATP-dependent helicase C-terminal	-	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
CH3_k127_516319_29	517417.Cpar_0783	5.154e-10	62.0	2DIK4@1|root,303HI@2|Bacteria,1FFNU@1090|Chlorobi	1090|Chlorobi	S	Cysteine-rich CPXCG	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_CPXG
CH3_k127_516319_30	118173.KB235914_gene1673	9.625e-10	63.0	COG5548@1|root,COG5548@2|Bacteria,1G997@1117|Cyanobacteria,1HCVD@1150|Oscillatoriales	1117|Cyanobacteria	S	Transmembrane proteins 14C	-	-	-	-	-	-	-	-	-	-	-	-	Tmemb_14
CH3_k127_516319_26	1117315.AHCA01000002_gene3124	4.417e-17	88.0	2EVE0@1|root,33NUD@2|Bacteria,1NMKR@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	zf-trcl
CH3_k127_516319_24	28072.Nos7524_4621	4.781e-22	113.0	COG0823@1|root,COG2304@1|root,COG3209@1|root,COG3210@1|root,COG0823@2|Bacteria,COG2304@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,1GQ0G@1117|Cyanobacteria,1HN8U@1161|Nostocales	1117|Cyanobacteria	MU	Dystroglycan-type cadherin-like domains.	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,He_PIG,RHS_repeat
CH3_k127_516319_23	700598.Niako_5012	7.142e-35	156.0	COG2385@1|root,COG2385@2|Bacteria	2|Bacteria	D	sporulation resulting in formation of a cellular spore	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	Amidase_2,Amidase_3,ChW,SpoIID
CH3_k127_516319_28	203119.Cthe_2878	1.145e-12	79.0	COG3271@1|root,COG3271@2|Bacteria,1VXMN@1239|Firmicutes,251IP@186801|Clostridia,3WPTR@541000|Ruminococcaceae	186801|Clostridia	S	Papain-like cysteine protease AvrRpt2	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39
CH3_k127_516319_1	497964.CfE428DRAFT_5133	5.46e-285	885.0	COG1164@1|root,COG1164@2|Bacteria,46UYB@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Peptidase family M3	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
CH3_k127_516319_16	156889.Mmc1_0977	1.376e-78	273.0	COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria,2TQMD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	GM	3-beta hydroxysteroid dehydrogenase	MA20_24380	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	3Beta_HSD,Epimerase,NAD_binding_10,RmlD_sub_bind
CH3_k127_516319_12	1304885.AUEY01000001_gene3217	6.793e-105	357.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2MIB8@213118|Desulfobacterales	28221|Deltaproteobacteria	T	response regulator receiver	-	-	-	ko:K02481,ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CH3_k127_516319_22	1329516.JPST01000035_gene3088	4.6e-39	158.0	COG2071@1|root,COG2071@2|Bacteria,1V1KC@1239|Firmicutes,4HI59@91061|Bacilli,27BT7@186824|Thermoactinomycetaceae	91061|Bacilli	S	Peptidase C26	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
CH3_k127_516319_20	497964.CfE428DRAFT_4165	2.982e-56	200.0	COG0245@1|root,COG0245@2|Bacteria,46T29@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	4.6.1.12	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
CH3_k127_516319_19	1396141.BATP01000003_gene5267	2.723e-66	229.0	COG0394@1|root,COG0394@2|Bacteria,46T52@74201|Verrucomicrobia,2IUEU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Low molecular weight phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	LMWPc
CH3_k127_516319_11	452637.Oter_2356	1.964e-112	373.0	COG0016@1|root,COG0016@2|Bacteria,46S6R@74201|Verrucomicrobia,3K7U5@414999|Opitutae	414999|Opitutae	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
CH3_k127_516319_13	452637.Oter_3509	3.827e-104	353.0	COG0673@1|root,COG0673@2|Bacteria,46TMZ@74201|Verrucomicrobia,3K8Y2@414999|Opitutae	414999|Opitutae	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CH3_k127_516319_10	886293.Sinac_7126	5.786e-115	384.0	COG1524@1|root,COG1524@2|Bacteria,2IYCV@203682|Planctomycetes	203682|Planctomycetes	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
CH3_k127_516319_6	452637.Oter_0961	2.485e-153	495.0	COG1171@1|root,COG1171@2|Bacteria,46TW9@74201|Verrucomicrobia,3K73X@414999|Opitutae	414999|Opitutae	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
CH3_k127_516319_3	1125863.JAFN01000001_gene1869	1.113e-184	606.0	COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2WJ7V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Phenylalanyl-tRNA synthetase, beta subunit	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
CH3_k127_516319_27	1283300.ATXB01000002_gene3058	9.308e-14	76.0	COG0861@1|root,COG0861@2|Bacteria	2|Bacteria	P	Integral membrane protein TerC family	-	-	-	-	-	-	-	-	-	-	-	-	PGPGW
CH3_k127_516319_5	497964.CfE428DRAFT_1519	3.713e-158	510.0	COG2204@1|root,COG2204@2|Bacteria,46SFT@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K11384	ko02020,map02020	M00505	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CH3_k127_516319_7	497964.CfE428DRAFT_1517	8.363e-142	474.0	COG5002@1|root,COG5002@2|Bacteria,46SJH@74201|Verrucomicrobia	74201|Verrucomicrobia	T	HAMP domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
CH3_k127_516319_33	443143.GM18_1663	0.0001785	51.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_3,DUF4347,HemolysinCabind,Phosphoesterase,VCBS,fn3
CH3_k127_516319_14	794903.OPIT5_30840	4.483e-91	312.0	COG0836@1|root,COG0836@2|Bacteria,46UR9@74201|Verrucomicrobia,3K7G3@414999|Opitutae	414999|Opitutae	M	Nucleotidyl transferase	-	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
CH3_k127_516319_15	497964.CfE428DRAFT_0832	2.685e-89	303.0	COG0159@1|root,COG0159@2|Bacteria,46SK1@74201|Verrucomicrobia	74201|Verrucomicrobia	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
CH3_k127_516319_25	497964.CfE428DRAFT_5015	6.343e-19	87.0	COG1521@1|root,COG1521@2|Bacteria,46T0X@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
CH3_k127_5176683_1	1396418.BATQ01000127_gene2548	2.703e-164	531.0	COG0247@1|root,COG0247@2|Bacteria,46SAS@74201|Verrucomicrobia,2IUWH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Cysteine-rich domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
CH3_k127_5176683_3	1487953.JMKF01000016_gene2557	1.239e-30	124.0	COG4634@1|root,COG4634@2|Bacteria,1G79I@1117|Cyanobacteria,1HHDK@1150|Oscillatoriales	1117|Cyanobacteria	S	Mut7-C RNAse domain	-	-	-	-	-	-	-	-	-	-	-	-	Mut7-C
CH3_k127_5176683_4	234267.Acid_5681	5.473e-22	96.0	COG2442@1|root,COG2442@2|Bacteria	2|Bacteria	K	InterPro IPR007367	-	-	-	-	-	-	-	-	-	-	-	-	DUF433,MerR_1
CH3_k127_5176683_0	497964.CfE428DRAFT_1010	5.665e-200	634.0	COG0277@1|root,COG0277@2|Bacteria,46S85@74201|Verrucomicrobia	74201|Verrucomicrobia	C	FAD linked oxidases, C-terminal domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
CH3_k127_5176683_2	1225184.ALXE01000045_gene621	6.348e-105	352.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,3VZMI@53335|Pantoea	1236|Gammaproteobacteria	C	Catalyzes the formation of succinate from succinate semialdehyde	gabD	GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0004777,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006105,GO:0006520,GO:0006536,GO:0006538,GO:0006540,GO:0006553,GO:0006554,GO:0006807,GO:0008150,GO:0008152,GO:0009013,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009066,GO:0009068,GO:0009448,GO:0009450,GO:0009987,GO:0016054,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0019477,GO:0019752,GO:0032787,GO:0036094,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046440,GO:0047949,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	iECIAI39_1322.ECIAI39_2847,iYL1228.KPN_00256	Aldedh
CH3_k127_5217209_2	714943.Mucpa_3747	2.288e-18	94.0	COG4733@1|root,COG4733@2|Bacteria,4NTXR@976|Bacteroidetes,1IZ2D@117747|Sphingobacteriia	976|Bacteroidetes	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Laminin_G_3
CH3_k127_5217209_3	661478.OP10G_0157	8.514e-07	52.0	COG1783@1|root,COG1783@2|Bacteria	2|Bacteria	S	DNA packaging	-	-	-	ko:K06909	-	-	-	-	ko00000	-	-	-	Terminase_3,Terminase_6
CH3_k127_5217209_1	323850.Shew_3184	5.277e-20	97.0	2CJG1@1|root,32S2C@2|Bacteria,1N0F3@1224|Proteobacteria,1SAUC@1236|Gammaproteobacteria,2QD4I@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4823)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4823
CH3_k127_5217209_0	1192034.CAP_3089	5.786e-48	184.0	COG0402@1|root,COG2374@1|root,COG0402@2|Bacteria,COG2374@2|Bacteria,1NFUA@1224|Proteobacteria,433MB@68525|delta/epsilon subdivisions,2WXJF@28221|Deltaproteobacteria,2YUGP@29|Myxococcales	28221|Deltaproteobacteria	F	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,DUF4215,LTD,TSP_3
CH3_k127_522436_4	452637.Oter_2161	3.738e-34	132.0	COG4307@1|root,COG4307@2|Bacteria	2|Bacteria	T	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_Mx,zinc-ribbon_6
CH3_k127_522436_1	497964.CfE428DRAFT_4519	5.413e-77	266.0	COG0388@1|root,COG0388@2|Bacteria,46T1B@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
CH3_k127_522436_5	204669.Acid345_3346	7.011e-33	136.0	2E0G4@1|root,32W27@2|Bacteria	2|Bacteria	S	LexA-binding, inner membrane-associated putative hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	YdjM
CH3_k127_522436_6	1201288.M900_1405	9.831e-16	88.0	COG1280@1|root,COG1280@2|Bacteria,1N227@1224|Proteobacteria,43DA6@68525|delta/epsilon subdivisions,2WVZZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
CH3_k127_522436_2	497964.CfE428DRAFT_0263	2.048e-71	254.0	COG1183@1|root,COG1183@2|Bacteria,46SK0@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
CH3_k127_522436_3	497964.CfE428DRAFT_0262	1.285e-41	161.0	COG0688@1|root,COG0688@2|Bacteria,46VRI@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
CH3_k127_522436_0	497964.CfE428DRAFT_0257	8.837e-223	721.0	COG2844@1|root,COG2844@2|Bacteria,46SI6@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	DUF294,GlnD_UR_UTase,GlnE,HD,NTP_transf_2
CH3_k127_5237656_1	391625.PPSIR1_09091	9.497e-12	77.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,43BQ2@68525|delta/epsilon subdivisions,2WQ6X@28221|Deltaproteobacteria,2Z2WS@29|Myxococcales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GGDEF,Yop-YscD_cpl
CH3_k127_5237656_0	1423807.BACO01000039_gene1231	1.06e-138	487.0	COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,4HB89@91061|Bacilli,3F478@33958|Lactobacillaceae	91061|Bacilli	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
CH3_k127_5250386_1	886293.Sinac_3711	2.406e-64	229.0	COG2896@1|root,COG2896@2|Bacteria,2IXWS@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
CH3_k127_5250386_3	452637.Oter_2046	8.709e-27	118.0	COG0466@1|root,COG0466@2|Bacteria,46WE2@74201|Verrucomicrobia,3K9NW@414999|Opitutae	414999|Opitutae	O	PFAM peptidase S16 lon domain protein	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	LON_substr_bdg
CH3_k127_5250386_4	1265505.ATUG01000001_gene3561	1.709e-10	68.0	2EAFJ@1|root,334IY@2|Bacteria,1NA2Y@1224|Proteobacteria,42VJ1@68525|delta/epsilon subdivisions,2WRKE@28221|Deltaproteobacteria,2MKY4@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1844)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1844
CH3_k127_5250386_2	1476973.JMMB01000007_gene3240	2.722e-34	146.0	COG0760@1|root,COG0760@2|Bacteria,1TX3R@1239|Firmicutes,24C7H@186801|Clostridia,25UIJ@186804|Peptostreptococcaceae	186801|Clostridia	M	SurA N-terminal domain	prsA	-	5.2.1.8	ko:K03769,ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
CH3_k127_5250386_0	497964.CfE428DRAFT_5481	4.819e-164	532.0	COG1052@1|root,COG1052@2|Bacteria,46SAN@74201|Verrucomicrobia	74201|Verrucomicrobia	CH	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
CH3_k127_5276694_46	498761.HM1_0138	8.758e-10	72.0	COG4733@1|root,COG5492@1|root,COG4733@2|Bacteria,COG5492@2|Bacteria,1UHXK@1239|Firmicutes,25E6U@186801|Clostridia	186801|Clostridia	N	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CBM_X2,Flg_new,I-set,Laminin_G_3,SLH
CH3_k127_5276694_5	1232410.KI421425_gene1538	1.192e-165	542.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,42R8H@68525|delta/epsilon subdivisions,2WMWF@28221|Deltaproteobacteria,43T80@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	PEGA,Plug,TonB_dep_Rec
CH3_k127_5276694_23	1167006.UWK_00360	2.528e-66	237.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,42PWS@68525|delta/epsilon subdivisions,2WKI5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TPR_8,TonB_dep_Rec
CH3_k127_5276694_47	228405.HNE_2756	1.277e-06	57.0	COG0322@1|root,COG0322@2|Bacteria,1PVWI@1224|Proteobacteria,2V74B@28211|Alphaproteobacteria,4402D@69657|Hyphomonadaceae	28211|Alphaproteobacteria	L	COG0322 Nuclease subunit of the excinuclease complex	-	-	-	-	-	-	-	-	-	-	-	-	GIY-YIG
CH3_k127_5276694_1	448385.sce4763	5.362e-217	691.0	COG1297@1|root,COG1297@2|Bacteria,1N7SK@1224|Proteobacteria,42PMM@68525|delta/epsilon subdivisions,2X37C@28221|Deltaproteobacteria,2YUQZ@29|Myxococcales	28221|Deltaproteobacteria	S	OPT oligopeptide transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	OPT
CH3_k127_5276694_26	313624.NSP_27450	5.534e-52	203.0	COG1075@1|root,COG1075@2|Bacteria,1GIQY@1117|Cyanobacteria,1HP99@1161|Nostocales	1117|Cyanobacteria	S	Alpha/beta hydrolase of unknown function (DUF900)	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_5276694_9	573065.Astex_0235	1.431e-137	449.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,2TRXK@28211|Alphaproteobacteria,2KEYZ@204458|Caulobacterales	204458|Caulobacterales	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
CH3_k127_5276694_30	497964.CfE428DRAFT_4129	6.604e-41	155.0	COG0346@1|root,COG0346@2|Bacteria,46T5V@74201|Verrucomicrobia	74201|Verrucomicrobia	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CH3_k127_5276694_8	382464.ABSI01000011_gene3117	1.803e-148	475.0	COG0074@1|root,COG0074@2|Bacteria,46TRM@74201|Verrucomicrobia,2ITVZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
CH3_k127_5276694_13	1173028.ANKO01000195_gene5986	2.489e-104	350.0	COG0642@1|root,COG0745@1|root,COG0642@2|Bacteria,COG0745@2|Bacteria,1G1M7@1117|Cyanobacteria,1H7YE@1150|Oscillatoriales	1117|Cyanobacteria	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg,STAS
CH3_k127_5276694_4	1121017.AUFG01000010_gene1661	1.413e-174	557.0	COG0372@1|root,COG0372@2|Bacteria,2GJ7E@201174|Actinobacteria,4FEQ1@85021|Intrasporangiaceae	201174|Actinobacteria	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
CH3_k127_5276694_12	886293.Sinac_1763	6.992e-129	424.0	COG1830@1|root,COG1830@2|Bacteria,2IXP8@203682|Planctomycetes	203682|Planctomycetes	G	Aldolase	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_5276694_18	794903.OPIT5_04235	2.05e-91	312.0	COG0235@1|root,COG0235@2|Bacteria,46UR3@74201|Verrucomicrobia,3K7W3@414999|Opitutae	414999|Opitutae	G	Class II Aldolase and Adducin N-terminal domain	-	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
CH3_k127_5276694_38	278957.ABEA03000086_gene2503	2.249e-22	101.0	COG4576@1|root,COG4576@2|Bacteria,46WMY@74201|Verrucomicrobia,3K8EE@414999|Opitutae	414999|Opitutae	CQ	Ethanolamine utilisation protein EutN/carboxysome	-	-	-	-	-	-	-	-	-	-	-	-	EutN_CcmL
CH3_k127_5276694_39	1123242.JH636435_gene1239	3.903e-20	94.0	COG4576@1|root,COG4576@2|Bacteria,2J0UQ@203682|Planctomycetes	203682|Planctomycetes	CQ	PFAM Ethanolamine utilization protein EutN carboxysome structural protein Ccml	-	-	-	ko:K04028	-	-	-	-	ko00000	-	-	-	EutN_CcmL
CH3_k127_5276694_3	452637.Oter_1295	4.293e-175	562.0	COG1012@1|root,COG1012@2|Bacteria,46UYV@74201|Verrucomicrobia,3K7HF@414999|Opitutae	414999|Opitutae	C	Aldehyde dehydrogenase family	-	-	-	ko:K04021	ko00620,ko01100,ko01120,map00620,map01100,map01120	-	R00228	RC00004,RC01195	ko00000,ko00001	-	-	-	Aldedh
CH3_k127_5276694_25	1403819.BATR01000059_gene1822	2.922e-55	196.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	5.3.3.19	ko:K19547	ko01130,map01130	M00787	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Cupin_2,HATPase_c,His_kinase,PocR
CH3_k127_5276694_31	278957.ABEA03000086_gene2506	8.742e-37	141.0	COG4576@1|root,COG4576@2|Bacteria,46VMK@74201|Verrucomicrobia,3K8BF@414999|Opitutae	414999|Opitutae	CQ	Ethanolamine utilisation protein EutN/carboxysome	-	-	-	ko:K04028	-	-	-	-	ko00000	-	-	-	EutN_CcmL
CH3_k127_5276694_37	794903.OPIT5_04210	5.565e-31	125.0	COG4577@1|root,COG4577@2|Bacteria,46W1J@74201|Verrucomicrobia,3K8AE@414999|Opitutae	414999|Opitutae	CQ	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
CH3_k127_5276694_7	794903.OPIT5_04205	1.128e-148	484.0	COG0282@1|root,COG0282@2|Bacteria,46TZF@74201|Verrucomicrobia,3K7U1@414999|Opitutae	414999|Opitutae	H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
CH3_k127_5276694_33	452637.Oter_1291	2.565e-35	137.0	COG4577@1|root,COG4577@2|Bacteria,46WBA@74201|Verrucomicrobia,3K89K@414999|Opitutae	414999|Opitutae	CQ	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
CH3_k127_5276694_34	794903.OPIT5_04195	2.659e-33	130.0	COG4577@1|root,COG4577@2|Bacteria,46W7U@74201|Verrucomicrobia,3K8C2@414999|Opitutae	414999|Opitutae	CQ	BMC	-	-	-	ko:K04027	-	-	-	-	ko00000	-	-	-	BMC
CH3_k127_5276694_15	278957.ABEA03000087_gene601	2.807e-101	343.0	COG4869@1|root,COG4869@2|Bacteria,46UMP@74201|Verrucomicrobia,3K7FS@414999|Opitutae	414999|Opitutae	Q	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	PTAC
CH3_k127_5276694_27	314230.DSM3645_04975	5.865e-50	188.0	COG1349@1|root,COG1349@2|Bacteria,2IYW0@203682|Planctomycetes	203682|Planctomycetes	K	COG1349 Transcriptional regulators of sugar metabolism	-	-	-	-	-	-	-	-	-	-	-	-	DeoRC,HTH_DeoR
CH3_k127_5276694_11	886293.Sinac_2714	1.646e-133	441.0	COG0673@1|root,COG0673@2|Bacteria,2IXFW@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CH3_k127_5276694_24	240016.ABIZ01000001_gene272	1.572e-63	229.0	COG0859@1|root,COG0859@2|Bacteria,46SZK@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
CH3_k127_5276694_42	794903.OPIT5_29490	3.548e-16	86.0	2EEN4@1|root,338G1@2|Bacteria,46T5X@74201|Verrucomicrobia,3K81C@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_5276694_40	1396418.BATQ01000085_gene1078	2.139e-18	87.0	COG0304@1|root,COG0304@2|Bacteria	2|Bacteria	I	3-oxoacyl-[acyl-carrier-protein] synthase activity	spoVAD	-	-	ko:K06406	-	-	-	-	ko00000	-	-	-	SpoVAD
CH3_k127_5276694_35	502025.Hoch_6396	2.765e-33	144.0	2DBMC@1|root,2Z9YC@2|Bacteria,1PY40@1224|Proteobacteria,43E0Z@68525|delta/epsilon subdivisions,2WZDV@28221|Deltaproteobacteria,2Z1X8@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_5276694_10	1089553.Tph_c08510	3.224e-137	448.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,25E76@186801|Clostridia,42FB3@68295|Thermoanaerobacterales	186801|Clostridia	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
CH3_k127_5276694_43	661478.OP10G_4802	3.082e-14	82.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02650,ko:K02679	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10
CH3_k127_5276694_21	344747.PM8797T_07504	6.24e-71	250.0	COG0428@1|root,COG0428@2|Bacteria,2IZ3C@203682|Planctomycetes	203682|Planctomycetes	P	ZIP Zinc transporter	-	-	-	ko:K16267	-	-	-	-	ko00000,ko02000	2.A.5.4.11	-	-	Zip
CH3_k127_5276694_22	517418.Ctha_1767	2.322e-67	237.0	COG2755@1|root,COG2755@2|Bacteria,1FET3@1090|Chlorobi	1090|Chlorobi	E	GDSL-like Lipase/Acylhydrolase family	-	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL_2
CH3_k127_5276694_16	1121957.ATVL01000008_gene3992	5.79e-94	315.0	COG4181@1|root,COG4181@2|Bacteria,4NEVZ@976|Bacteroidetes,47JSN@768503|Cytophagia	976|Bacteroidetes	Q	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CH3_k127_5276694_0	452637.Oter_0071	4.158e-222	717.0	COG3127@1|root,COG3127@2|Bacteria,46UKQ@74201|Verrucomicrobia,3K7U2@414999|Opitutae	414999|Opitutae	Q	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CH3_k127_5276694_20	756272.Plabr_1391	3.359e-79	275.0	COG1082@1|root,COG1082@2|Bacteria,2IXXX@203682|Planctomycetes	203682|Planctomycetes	G	Xylose isomerase-like TIM barrel	-	-	5.1.3.22	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R03244	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	AP_endonuc_2
CH3_k127_5276694_6	1403819.BATR01000002_gene28	1.199e-156	505.0	COG1253@1|root,COG1253@2|Bacteria,46U7J@74201|Verrucomicrobia,2IVE3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
CH3_k127_5276694_28	489825.LYNGBM3L_17040	2.262e-48	186.0	COG1266@1|root,COG1266@2|Bacteria,1G5HB@1117|Cyanobacteria,1HAXC@1150|Oscillatoriales	1117|Cyanobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
CH3_k127_5276694_36	338966.Ppro_1664	4.037e-32	138.0	COG0470@1|root,COG0470@2|Bacteria,1MY1W@1224|Proteobacteria,43BTG@68525|delta/epsilon subdivisions,2X74B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DNA polymerase III, delta'	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
CH3_k127_5276694_45	755178.Cyan10605_0953	1.723e-10	73.0	COG3307@1|root,COG3307@2|Bacteria,1G1ZH@1117|Cyanobacteria	1117|Cyanobacteria	M	bicarbonate transporter, IctB family	ictB	-	-	ko:K18814	-	-	-	-	ko00000,ko02000	9.B.67.1	-	-	Wzy_C
CH3_k127_5276694_29	459349.CLOAM0160	1.758e-41	166.0	COG0671@1|root,COG0671@2|Bacteria,2NRVZ@2323|unclassified Bacteria	2|Bacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
CH3_k127_5276694_2	497964.CfE428DRAFT_3485	8.58e-176	559.0	COG0673@1|root,COG0673@2|Bacteria,46SBW@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CH3_k127_5276694_32	28444.JODQ01000006_gene629	1.099e-35	143.0	COG3963@1|root,COG3963@2|Bacteria,2I93P@201174|Actinobacteria,4EJ7V@85012|Streptosporangiales	201174|Actinobacteria	I	Phospholipid N-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,RrnaAD
CH3_k127_5276694_19	234267.Acid_7682	2.21e-89	309.0	COG2133@1|root,COG2133@2|Bacteria,3Y6W0@57723|Acidobacteria	57723|Acidobacteria	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,VCBS
CH3_k127_5276694_17	273068.TTE2349	9.231e-93	322.0	COG5520@1|root,COG5520@2|Bacteria,1TS99@1239|Firmicutes,249YD@186801|Clostridia,42HSQ@68295|Thermoanaerobacterales	186801|Clostridia	G	Belongs to the glycosyl hydrolase 30 family	-	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	Glyco_hydro_30,Glyco_hydro_30C
CH3_k127_5276694_14	1132441.KI519454_gene1142	1.99e-103	351.0	COG1554@1|root,COG1554@2|Bacteria,2GJXJ@201174|Actinobacteria	201174|Actinobacteria	G	Glycosyl hydrolase family 65, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_5324777_23	1267535.KB906767_gene1409	1.144e-08	62.0	COG0491@1|root,COG0491@2|Bacteria,3Y44S@57723|Acidobacteria,2JHNA@204432|Acidobacteriia	204432|Acidobacteriia	S	Metallo-beta-lactamase superfamily	-	-	3.5.2.6	ko:K17837	ko01501,map01501	-	R06363	RC01499	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
CH3_k127_5324777_5	497964.CfE428DRAFT_0621	9.789e-121	400.0	COG0150@1|root,COG0150@2|Bacteria,46SJ4@74201|Verrucomicrobia	74201|Verrucomicrobia	F	AIR synthase related protein domain protein	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
CH3_k127_5324777_6	1123242.JH636435_gene3064	8.859e-109	368.0	COG0477@1|root,COG0477@2|Bacteria,2IX7U@203682|Planctomycetes	203682|Planctomycetes	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
CH3_k127_5324777_12	1123073.KB899243_gene738	3.292e-60	217.0	COG1392@1|root,COG1392@2|Bacteria,1PKQF@1224|Proteobacteria,1SMFE@1236|Gammaproteobacteria,1X412@135614|Xanthomonadales	135614|Xanthomonadales	P	Pit accessory protein	VL23_21310	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
CH3_k127_5324777_3	1300345.LF41_544	9.921e-147	473.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,1RP0Q@1236|Gammaproteobacteria,1X3YD@135614|Xanthomonadales	135614|Xanthomonadales	P	phosphate transporter	pitA	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
CH3_k127_5324777_4	794903.OPIT5_05545	1.753e-133	443.0	COG0306@1|root,COG0306@2|Bacteria,46SDP@74201|Verrucomicrobia,3K7HD@414999|Opitutae	414999|Opitutae	P	phosphate transporter	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
CH3_k127_5324777_7	398512.JQKC01000010_gene143	1.96e-108	368.0	COG1305@1|root,COG1305@2|Bacteria,1TT33@1239|Firmicutes,24B27@186801|Clostridia,3WPMU@541000|Ruminococcaceae	186801|Clostridia	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
CH3_k127_5324777_0	321327.CYA_2098	0.0	1191.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1G1HW@1117|Cyanobacteria,1GYMF@1129|Synechococcus	1117|Cyanobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
CH3_k127_5324777_18	179408.Osc7112_2750	6.138e-23	105.0	2CBW6@1|root,332FE@2|Bacteria,1G8ER@1117|Cyanobacteria,1HD3G@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_5324777_21	41431.PCC8801_4303	5.527e-18	87.0	2B7MA@1|root,320SE@2|Bacteria,1GH4S@1117|Cyanobacteria,3KIW8@43988|Cyanothece	1117|Cyanobacteria	S	Domain of unknown function (DUF4926)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4926
CH3_k127_5324777_20	65093.PCC7418_1380	5.425e-18	85.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1G1HW@1117|Cyanobacteria	1117|Cyanobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
CH3_k127_5324777_1	452637.Oter_0138	1.432e-213	690.0	COG3934@1|root,COG3934@2|Bacteria,46YQT@74201|Verrucomicrobia,3KA0N@414999|Opitutae	414999|Opitutae	G	Cellulase (glycosyl hydrolase family 5)	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_5324777_16	497964.CfE428DRAFT_2588	4.707e-40	162.0	COG2374@1|root,COG2374@2|Bacteria,46VEK@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM Endonuclease exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CH3_k127_5324777_8	497964.CfE428DRAFT_3386	3.513e-104	345.0	COG1469@1|root,COG1469@2|Bacteria,46SIB@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Converts GTP to 7,8-dihydroneopterin triphosphate	folE2	-	3.5.4.16	ko:K09007	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GCHY-1
CH3_k127_5324777_17	497964.CfE428DRAFT_2343	3.845e-31	130.0	COG1734@1|root,COG1734@2|Bacteria,46SVY@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Prokaryotic dksA/traR C4-type zinc finger	dksA	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
CH3_k127_5324777_19	1353529.M899_0700	1.099e-19	89.0	COG0267@1|root,COG0267@2|Bacteria,1Q1V0@1224|Proteobacteria,437HE@68525|delta/epsilon subdivisions,2MTDQ@213481|Bdellovibrionales,2X2QY@28221|Deltaproteobacteria	213481|Bdellovibrionales	J	Ribosomal protein L33	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
CH3_k127_5324777_22	497964.CfE428DRAFT_2341	3.871e-13	77.0	COG0238@1|root,COG0238@2|Bacteria,46TBC@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Ribosomal protein S18	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
CH3_k127_5324777_11	5786.XP_003293123.1	2.387e-65	242.0	COG1409@1|root,KOG1378@2759|Eukaryota,3XGP6@554915|Amoebozoa	554915|Amoebozoa	S	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Pur_ac_phosph_N
CH3_k127_5324777_10	240016.ABIZ01000001_gene2631	3.213e-85	302.0	COG4745@1|root,COG4745@2|Bacteria,46T45@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CH3_k127_5324777_14	452637.Oter_3514	1.186e-44	171.0	2F286@1|root,33V6C@2|Bacteria,46V8R@74201|Verrucomicrobia,3K9H5@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_5324777_15	452637.Oter_3514	4.609e-44	170.0	2F286@1|root,33V6C@2|Bacteria,46V8R@74201|Verrucomicrobia,3K9H5@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_5324777_13	497964.CfE428DRAFT_6358	5.386e-54	198.0	COG0204@1|root,COG0204@2|Bacteria,46VUC@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
CH3_k127_5324777_9	300852.55771566	3.862e-104	353.0	COG0508@1|root,COG0508@2|Bacteria,1WI1G@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Component of pyruvate dehydrogenase complex	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
CH3_k127_5324777_2	105559.Nwat_1144	7.536e-156	505.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RMFF@1236|Gammaproteobacteria,1WWGK@135613|Chromatiales	135613|Chromatiales	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim
CH3_k127_5324777_24	1210884.HG799464_gene10380	1.179e-07	53.0	COG3293@1|root,COG3293@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	ko:K07492	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
CH3_k127_5335579_5	497964.CfE428DRAFT_4990	3.294e-20	93.0	COG3071@1|root,COG3071@2|Bacteria,46VFP@74201|Verrucomicrobia	74201|Verrucomicrobia	H	HemY protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_5335579_2	469383.Cwoe_4579	1.611e-60	219.0	COG1994@1|root,COG1994@2|Bacteria,2H6BD@201174|Actinobacteria,4CS7E@84995|Rubrobacteria	84995|Rubrobacteria	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_5335579_3	452637.Oter_4555	5.086e-55	198.0	2C0ZJ@1|root,33VV4@2|Bacteria,46VGY@74201|Verrucomicrobia,3K7JZ@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_5335579_0	696369.KI912183_gene1481	4.339e-104	349.0	COG0337@1|root,COG0337@2|Bacteria,1TPKZ@1239|Firmicutes,248H4@186801|Clostridia,25ZZM@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
CH3_k127_5335579_1	794903.OPIT5_16130	7.436e-93	314.0	COG1028@1|root,COG1028@2|Bacteria,46TD2@74201|Verrucomicrobia,3K7W5@414999|Opitutae	414999|Opitutae	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CH3_k127_5335579_4	234267.Acid_1134	1.3e-27	113.0	COG4225@1|root,COG4225@2|Bacteria,3Y6Y6@57723|Acidobacteria	57723|Acidobacteria	S	Glycosyl Hydrolase Family 88	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_88
CH3_k127_53937_0	761193.Runsl_3310	1.845e-115	387.0	COG0673@1|root,COG0673@2|Bacteria,4NGHJ@976|Bacteroidetes,47NH0@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CH3_k127_53937_1	1396141.BATP01000003_gene5218	4.097e-74	260.0	COG2503@1|root,COG2503@2|Bacteria,46U63@74201|Verrucomicrobia	74201|Verrucomicrobia	S	HAD superfamily, subfamily IIIB (Acid phosphatase)	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_53937_2	504472.Slin_2796	4.623e-63	223.0	COG3669@1|root,COG3669@2|Bacteria,4NE74@976|Bacteroidetes,47KQM@768503|Cytophagia	976|Bacteroidetes	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,F5_F8_type_C
CH3_k127_542943_0	452637.Oter_1502	1.77e-62	223.0	COG1131@1|root,COG1131@2|Bacteria,46UCI@74201|Verrucomicrobia,3K7BH@414999|Opitutae	2|Bacteria	V	PFAM ABC transporter related	ecsA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CH3_k127_5442410_6	1286106.MPL1_04567	1.835e-81	282.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,1RMTF@1236|Gammaproteobacteria,45ZYC@72273|Thiotrichales	72273|Thiotrichales	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
CH3_k127_5442410_5	452637.Oter_3564	5.363e-86	300.0	COG2518@1|root,COG2518@2|Bacteria,46UEK@74201|Verrucomicrobia,3K7SY@414999|Opitutae	414999|Opitutae	O	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_32
CH3_k127_5442410_10	574087.Acear_2177	7.724e-28	127.0	COG0795@1|root,COG0795@2|Bacteria,1TRZG@1239|Firmicutes,24CCP@186801|Clostridia,3WAFW@53433|Halanaerobiales	186801|Clostridia	S	Permease YjgP YjgQ family	-	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
CH3_k127_5442410_3	1156937.MFUM_230006	1.251e-119	405.0	COG1956@1|root,COG2203@1|root,COG4191@1|root,COG1956@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,46SAZ@74201|Verrucomicrobia,37G69@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
CH3_k127_5442410_9	497964.CfE428DRAFT_0221	9.381e-40	155.0	2EKW2@1|root,33EJK@2|Bacteria,46VZV@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_5442410_7	1403819.BATR01000031_gene1028	6.313e-61	218.0	COG0571@1|root,COG0571@2|Bacteria,46T3X@74201|Verrucomicrobia,2IU7S@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
CH3_k127_5442410_2	1031288.AXAA01000009_gene666	7.818e-168	548.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia,36DCW@31979|Clostridiaceae	186801|Clostridia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsP	-	2.7.3.9,2.7.9.2	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
CH3_k127_5442410_4	497964.CfE428DRAFT_4748	8.159e-97	323.0	COG1208@1|root,COG1208@2|Bacteria,46V3X@74201|Verrucomicrobia	74201|Verrucomicrobia	JM	Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
CH3_k127_5442410_0	452637.Oter_3558	3.615e-250	779.0	COG1032@1|root,COG1032@2|Bacteria,46V7P@74201|Verrucomicrobia,3K74V@414999|Opitutae	414999|Opitutae	C	Domain of unknown function (DUF4070)	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
CH3_k127_5442410_1	1403819.BATR01000125_gene4494	8.307e-181	604.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,46UI8@74201|Verrucomicrobia,2IV8V@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Y_Y_Y domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
CH3_k127_5442410_11	1396141.BATP01000057_gene2996	7.83e-21	94.0	COG2197@1|root,COG2197@2|Bacteria,46XBG@74201|Verrucomicrobia,2IVB3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CH3_k127_5443998_1	243090.RB9551	1.26e-137	448.0	COG0003@1|root,COG0003@2|Bacteria,2IY37@203682|Planctomycetes	203682|Planctomycetes	P	TIGRFAM arsenite-activated ATPase (arsA)	-	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
CH3_k127_5443998_6	1254432.SCE1572_04640	3.521e-32	129.0	2DMHQ@1|root,32RMG@2|Bacteria,1RI3A@1224|Proteobacteria,42V0J@68525|delta/epsilon subdivisions,2WRQ5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Arsenical resistance operon trans-acting repressor ArsD	-	-	-	-	-	-	-	-	-	-	-	-	ArsD
CH3_k127_5443998_8	344747.PM8797T_22568	1.156e-08	60.0	2EPBI@1|root,33GYA@2|Bacteria,2J1HU@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_5443998_3	1396141.BATP01000003_gene5267	9.167e-74	252.0	COG0394@1|root,COG0394@2|Bacteria,46T52@74201|Verrucomicrobia,2IUEU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Low molecular weight phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	LMWPc
CH3_k127_5443998_4	706587.Desti_5389	5.561e-36	140.0	COG0640@1|root,COG0640@2|Bacteria,1MZT1@1224|Proteobacteria,42V3T@68525|delta/epsilon subdivisions,2WS3M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	regulatory protein, arsR	-	-	-	ko:K03892,ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
CH3_k127_5443998_2	909663.KI867150_gene1425	9.934e-101	332.0	COG4232@1|root,COG4232@2|Bacteria,1PK9S@1224|Proteobacteria,42PV0@68525|delta/epsilon subdivisions,2WJPK@28221|Deltaproteobacteria,2MS43@213462|Syntrophobacterales	28221|Deltaproteobacteria	CO	PFAM cytochrome c biogenesis protein, transmembrane region	dsbD	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
CH3_k127_5443998_5	452637.Oter_4059	2.274e-32	141.0	COG0526@1|root,COG0526@2|Bacteria,46W21@74201|Verrucomicrobia	74201|Verrucomicrobia	CO	Thioredoxin	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
CH3_k127_5443998_7	665571.STHERM_c11400	7.878e-19	99.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	DUF4369,Thioredoxin_3
CH3_k127_5443998_0	1499967.BAYZ01000050_gene2840	1.133e-194	614.0	COG0701@1|root,COG0701@2|Bacteria,2NP6A@2323|unclassified Bacteria	2|Bacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
CH3_k127_5461478_3	497964.CfE428DRAFT_0066	7.664e-79	295.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,46TTW@74201|Verrucomicrobia	74201|Verrucomicrobia	KLT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PEGA,Pkinase
CH3_k127_5461478_5	1210884.HG799463_gene9871	8.686e-27	128.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2IXZY@203682|Planctomycetes	203682|Planctomycetes	T	COG0515 Serine threonine protein	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_10,TPR_11,TPR_12,WD40
CH3_k127_5461478_2	1082933.MEA186_23031	3.341e-184	589.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	3.1.3.2,3.6.1.27	ko:K09474,ko:K19302	ko00550,ko00740,ko01100,ko02020,map00550,map00740,map01100,map02020	-	R00548,R05627	RC00002,RC00017	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
CH3_k127_5461478_4	349741.Amuc_1517	6.621e-49	182.0	COG1595@1|root,COG1595@2|Bacteria,46VJP@74201|Verrucomicrobia,2IU42@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
CH3_k127_5461478_6	118168.MC7420_7676	6.279e-09	59.0	COG0493@1|root,COG0493@2|Bacteria,1G0SD@1117|Cyanobacteria,1H8CN@1150|Oscillatoriales	1117|Cyanobacteria	E	TIGRFAM glutamate synthases, NADH NADPH, small subunit	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	iJN678.gltD	Fer4_20,Pyr_redox_2
CH3_k127_5461478_7	1379281.AVAG01000028_gene128	2.278e-07	55.0	COG1598@1|root,COG1598@2|Bacteria,1NPTZ@1224|Proteobacteria,431E8@68525|delta/epsilon subdivisions,2WWUI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_5461478_1	497965.Cyan7822_2990	7.608e-281	868.0	COG0493@1|root,COG0493@2|Bacteria,1G0SD@1117|Cyanobacteria,3KJF4@43988|Cyanothece	1117|Cyanobacteria	C	TIGRFAM glutamate synthase, NADH NADPH, small subunit	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	iJN678.gltD	Fer4_20,Pyr_redox_2
CH3_k127_5461478_0	1173028.ANKO01000041_gene3220	0.0	1663.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1G0XM@1117|Cyanobacteria,1H9JF@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Conserved region in glutamate synthase	gltB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.7.1	ko:K00284	ko00630,ko00910,ko01120,map00630,map00910,map01120	-	R00021,R10086	RC00006,RC00010	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
CH3_k127_5468001_3	316274.Haur_4549	3.929e-36	149.0	COG2335@1|root,COG5492@1|root,COG2335@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CHRD,Fasciclin
CH3_k127_5468001_0	760192.Halhy_6811	1.276e-164	530.0	COG3119@1|root,COG3119@2|Bacteria,4NEQ5@976|Bacteroidetes,1IRRQ@117747|Sphingobacteriia	976|Bacteroidetes	P	PFAM sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CH3_k127_5468001_1	1120999.JONM01000003_gene2723	7.495e-62	217.0	COG1510@1|root,COG1510@2|Bacteria,1RA49@1224|Proteobacteria,2VQNT@28216|Betaproteobacteria,2KQ5T@206351|Neisseriales	206351|Neisseriales	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
CH3_k127_5468001_5	710687.KI912270_gene983	6.737e-12	72.0	COG3011@1|root,COG3011@2|Bacteria,2HS35@201174|Actinobacteria,23ABV@1762|Mycobacteriaceae	201174|Actinobacteria	S	Protein of unknown function, DUF393	-	-	-	-	-	-	-	-	-	-	-	-	DUF393
CH3_k127_5468001_2	314230.DSM3645_07370	2.259e-49	194.0	295WE@1|root,2ZT7B@2|Bacteria,2J2RS@203682|Planctomycetes	203682|Planctomycetes	S	Membrane bound O-acyl transferase family	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT_2
CH3_k127_5468001_4	240016.ABIZ01000001_gene5918	3.728e-16	87.0	2DS4P@1|root,33EH8@2|Bacteria,46XKS@74201|Verrucomicrobia,2IW5C@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_5468302_2	247490.KSU1_B0180	1.436e-14	77.0	COG2841@1|root,COG2841@2|Bacteria,2J45A@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF465)	-	-	-	-	-	-	-	-	-	-	-	-	DUF465
CH3_k127_5468302_0	452637.Oter_3094	1.393e-81	296.0	COG2202@1|root,COG2208@1|root,COG2202@2|Bacteria,COG2208@2|Bacteria,46U96@74201|Verrucomicrobia	74201|Verrucomicrobia	KT	PFAM Stage II sporulation E family protein	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	PAS_3,PAS_4,SpoIIE
CH3_k127_5468302_1	497964.CfE428DRAFT_3537	1.026e-61	218.0	COG0621@1|root,COG0621@2|Bacteria,46S6B@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
CH3_k127_5488100_3	497964.CfE428DRAFT_3817	2.293e-78	267.0	COG1690@1|root,COG1690@2|Bacteria,46SU0@74201|Verrucomicrobia	74201|Verrucomicrobia	S	tRNA-splicing ligase RtcB	-	-	-	-	-	-	-	-	-	-	-	-	RtcB
CH3_k127_5488100_2	497964.CfE428DRAFT_2414	9.154e-98	335.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
CH3_k127_5488100_0	344747.PM8797T_22613	3.547e-152	491.0	COG4639@1|root,COG4639@2|Bacteria,2IZ4C@203682|Planctomycetes	203682|Planctomycetes	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33,HD
CH3_k127_5488100_1	1396418.BATQ01000161_gene5597	3.815e-119	389.0	COG1423@1|root,COG1423@2|Bacteria	2|Bacteria	L	RNA ligase	-	-	-	-	-	-	-	-	-	-	-	-	RNA_ligase
CH3_k127_5488100_4	240016.ABIZ01000001_gene428	1.62e-71	246.0	COG1403@1|root,COG1403@2|Bacteria,46UDR@74201|Verrucomicrobia,2IUK8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH_4
CH3_k127_5488100_5	267608.RSp0206	4.284e-11	64.0	COG3039@1|root,COG3039@2|Bacteria,1MVDK@1224|Proteobacteria,2VI1H@28216|Betaproteobacteria,1K3UX@119060|Burkholderiaceae	28216|Betaproteobacteria	L	PFAM transposase, IS4 family protein	-	-	-	ko:K07481	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DUF772
CH3_k127_5492013_0	240016.ABIZ01000001_gene2058	2.356e-193	615.0	COG0644@1|root,COG0644@2|Bacteria,46U5W@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Tryptophan halogenase	-	-	-	-	-	-	-	-	-	-	-	-	Trp_halogenase
CH3_k127_5508390_0	269798.CHU_2897	2.773e-77	283.0	COG1361@1|root,COG3291@1|root,COG1361@2|Bacteria,COG3291@2|Bacteria,4PKTY@976|Bacteroidetes,47RAA@768503|Cytophagia	976|Bacteroidetes	M	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	PKD,UnbV_ASPIC,VCBS
CH3_k127_5508390_3	740709.A10D4_00975	1.996e-05	51.0	COG1520@1|root,COG3209@1|root,COG3210@1|root,COG1520@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	yeeJ	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	CHU_C,Calx-beta,Flg_new,HYR,Laminin_G_3,PQQ_2
CH3_k127_5508390_2	1121957.ATVL01000014_gene1459	1.005e-11	70.0	COG5563@1|root,COG5563@2|Bacteria,4PHUI@976|Bacteroidetes,47VHU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_5508390_1	497964.CfE428DRAFT_4660	2.043e-26	114.0	COG1520@1|root,COG1520@2|Bacteria,46TSY@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CH3_k127_5508682_18	1303518.CCALI_00378	1.533e-17	93.0	COG4969@1|root,COG4969@2|Bacteria	2|Bacteria	NU	cell adhesion	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,SBP_bac_10
CH3_k127_5508682_13	1444309.JAQG01000181_gene3484	6.222e-34	148.0	COG2833@1|root,COG2833@2|Bacteria,1W5BJ@1239|Firmicutes,4I0UF@91061|Bacilli,26VKN@186822|Paenibacillaceae	91061|Bacilli	S	Protein of unknown function (DUF455)	-	-	-	-	-	-	-	-	-	-	-	-	DUF455
CH3_k127_5508682_9	1499967.BAYZ01000017_gene6249	2.372e-62	228.0	COG0407@1|root,COG0407@2|Bacteria,2NP39@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
CH3_k127_5508682_5	97139.C824_01928	2.167e-86	300.0	COG0673@1|root,COG0673@2|Bacteria,1TP83@1239|Firmicutes,248XQ@186801|Clostridia,36F4R@31979|Clostridiaceae	186801|Clostridia	S	Oxidoreductase family, C-terminal alpha beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CH3_k127_5508682_10	497964.CfE428DRAFT_2346	1.665e-52	198.0	COG3694@1|root,COG3694@2|Bacteria,46VPX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
CH3_k127_5508682_7	497964.CfE428DRAFT_2347	6.74e-71	249.0	COG4587@1|root,COG4587@2|Bacteria,46VAG@74201|Verrucomicrobia	74201|Verrucomicrobia	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
CH3_k127_5508682_0	1519464.HY22_04590	4.086e-242	768.0	COG0058@1|root,COG0058@2|Bacteria,1FD8Y@1090|Chlorobi	1090|Chlorobi	G	PFAM glycosyl transferase, family 35	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
CH3_k127_5508682_1	886293.Sinac_6975	1.502e-153	499.0	28KPG@1|root,2ZA7K@2|Bacteria,2J1E2@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_5508682_4	521674.Plim_2302	2.149e-93	321.0	COG0475@1|root,COG0475@2|Bacteria,2IZ8F@203682|Planctomycetes	203682|Planctomycetes	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
CH3_k127_5508682_3	240016.ABIZ01000001_gene4766	5.514e-119	390.0	COG0492@1|root,COG0492@2|Bacteria,46SC1@74201|Verrucomicrobia,2ITP4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
CH3_k127_5508682_16	497964.CfE428DRAFT_4596	2.342e-21	110.0	COG0745@1|root,COG1716@1|root,COG0745@2|Bacteria,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	ko:K02283,ko:K02454,ko:K03220,ko:K03466	ko03070,ko05111,map03070,map05111	M00331,M00332	-	-	ko00000,ko00001,ko00002,ko02035,ko02044,ko03036	3.A.12,3.A.15,3.A.6.1	-	-	Cytochrom_c3_2,FHA,FtsK_SpoIIIE,Response_reg,T2SSE,Yop-YscD_cpl,Yop-YscD_ppl
CH3_k127_5508682_15	497964.CfE428DRAFT_5353	1.199e-23	118.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,HATPase_c,HD_5,Response_reg,T2SSE_N
CH3_k127_5508682_11	452637.Oter_0887	1.245e-43	180.0	COG4726@1|root,COG4726@2|Bacteria,46VER@74201|Verrucomicrobia,3K9MT@414999|Opitutae	414999|Opitutae	NU	Pilus assembly protein PilX	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_5508682_6	497964.CfE428DRAFT_5952	1.766e-71	250.0	COG0745@1|root,COG0745@2|Bacteria,46V5I@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CH3_k127_5508682_2	497964.CfE428DRAFT_5953	3.156e-120	408.0	COG0642@1|root,COG2205@2|Bacteria,46Z6V@74201|Verrucomicrobia	74201|Verrucomicrobia	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
CH3_k127_5508682_8	595460.RRSWK_04460	4.065e-69	254.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
CH3_k127_5508682_19	519989.ECTPHS_00480	1.274e-05	51.0	COG0305@1|root,COG1372@1|root,COG0305@2|Bacteria,COG1372@2|Bacteria,1MUG9@1224|Proteobacteria,1RPM2@1236|Gammaproteobacteria,1WW1X@135613|Chromatiales	135613|Chromatiales	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	-	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C,Intein_splicing,LAGLIDADG_3
CH3_k127_5508682_14	1122917.KB899665_gene4007	1.778e-30	142.0	COG1572@1|root,COG2755@1|root,COG5434@1|root,COG5492@1|root,COG1572@2|Bacteria,COG2755@2|Bacteria,COG5434@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	xynX3	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	Big_2,DUF1735,Flg_new,Laminin_G_3,Lipase_GDSL_2,PrcB_C,SLH
CH3_k127_5508682_12	1286631.X805_07670	1.788e-38	169.0	COG2304@1|root,COG2373@1|root,COG2931@1|root,COG2304@2|Bacteria,COG2373@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2VKA9@28216|Betaproteobacteria,1KK67@119065|unclassified Burkholderiales	28216|Betaproteobacteria	Q	TIGRFAM outer membrane adhesin like proteiin	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4347,He_PIG,HemolysinCabind,VWA_2
CH3_k127_5508682_17	1123278.KB893598_gene2685	1.368e-17	100.0	COG3210@1|root,COG3391@1|root,COG3210@2|Bacteria,COG3391@2|Bacteria,4NTNN@976|Bacteroidetes,47K8B@768503|Cytophagia	976|Bacteroidetes	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Chlam_PMP,SprB
CH3_k127_5516463_0	521674.Plim_0789	0.0	1000.0	COG3119@1|root,COG3119@2|Bacteria,2IXNZ@203682|Planctomycetes	203682|Planctomycetes	P	PFAM sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
CH3_k127_5516463_3	1112204.GPOL_c26570	1.606e-26	113.0	COG2189@1|root,COG2189@2|Bacteria,2I8FH@201174|Actinobacteria	201174|Actinobacteria	L	DNA methylase	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
CH3_k127_5516463_4	1112212.JH584235_gene3224	2.34e-12	73.0	COG2189@1|root,COG2189@2|Bacteria,1MX9M@1224|Proteobacteria,2TRE4@28211|Alphaproteobacteria,2K22C@204457|Sphingomonadales	204457|Sphingomonadales	L	DNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	Mrr_cat,N6_N4_Mtase
CH3_k127_5516463_1	398767.Glov_2515	2.259e-41	160.0	2DGUS@1|root,32U80@2|Bacteria,1MZK3@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_5516463_5	443254.Marpi_0296	8.045e-08	56.0	COG1715@1|root,COG2189@1|root,COG1715@2|Bacteria,COG2189@2|Bacteria	2|Bacteria	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.72	ko:K00571,ko:K07316,ko:K07448	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	AAA_5,Mrr_N,Mrr_cat,N6_N4_Mtase
CH3_k127_5516463_2	1499967.BAYZ01000088_gene5060	1.343e-27	119.0	COG2189@1|root,COG2189@2|Bacteria,2NP0F@2323|unclassified Bacteria	2|Bacteria	L	PFAM DNA methylase N-4 N-6	-	-	2.1.1.72	ko:K00571,ko:K07316	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Mrr_cat,N6_N4_Mtase
CH3_k127_5528545_2	635013.TherJR_1425	1.341e-07	65.0	COG3005@1|root,COG4733@1|root,COG3005@2|Bacteria,COG4733@2|Bacteria,1UT1Y@1239|Firmicutes,250WR@186801|Clostridia,265BU@186807|Peptococcaceae	186801|Clostridia	C	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
CH3_k127_5528545_1	497964.CfE428DRAFT_5270	5.95e-73	251.0	COG1187@1|root,COG1187@2|Bacteria,46V8C@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.20	ko:K06181	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
CH3_k127_5528545_0	1397666.RS24_01915	2.605e-75	266.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2TRMU@28211|Alphaproteobacteria,4BPNB@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	NU	Type II/IV secretion system protein	gspE	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
CH3_k127_5528545_3	903818.KI912268_gene3020	0.000255	47.0	COG1459@1|root,COG1459@2|Bacteria,3Y2X8@57723|Acidobacteria	57723|Acidobacteria	NU	type II secretion system	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
CH3_k127_5540925_2	1291050.JAGE01000001_gene396	8.97e-91	314.0	COG1641@1|root,COG1641@2|Bacteria,1TPAV@1239|Firmicutes,247ZH@186801|Clostridia,3WGU1@541000|Ruminococcaceae	186801|Clostridia	S	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes	larC	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
CH3_k127_5540925_3	273068.TTE0770	8.035e-79	271.0	COG1691@1|root,COG1691@2|Bacteria,1TP0Z@1239|Firmicutes,24815@186801|Clostridia,42FCC@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
CH3_k127_5540925_4	765913.ThidrDRAFT_2196	2.164e-74	261.0	COG1089@1|root,COG1089@2|Bacteria,1R9QJ@1224|Proteobacteria,1S1QW@1236|Gammaproteobacteria,1WVZK@135613|Chromatiales	135613|Chromatiales	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	-	-	-	-	-	-	-	-	-	-	-	-	GDP_Man_Dehyd
CH3_k127_5540925_9	1304885.AUEY01000004_gene949	9.514e-23	101.0	COG1724@1|root,COG1724@2|Bacteria,1P42H@1224|Proteobacteria,433GK@68525|delta/epsilon subdivisions,2WXV2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
CH3_k127_5540925_8	1304885.AUEY01000004_gene950	2.591e-25	107.0	COG1598@1|root,COG1598@2|Bacteria,1NDQJ@1224|Proteobacteria,42WAM@68525|delta/epsilon subdivisions,2WRR1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
CH3_k127_5540925_0	880072.Desac_1923	1.498e-147	469.0	COG2519@1|root,COG2519@2|Bacteria,1MXAK@1224|Proteobacteria,42NCI@68525|delta/epsilon subdivisions,2WJUH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
CH3_k127_5540925_12	314292.VAS14_05908	8.589e-09	59.0	COG1089@1|root,COG1089@2|Bacteria,1MUX0@1224|Proteobacteria,1RMIY@1236|Gammaproteobacteria,1XWBR@135623|Vibrionales	135623|Vibrionales	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008446,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
CH3_k127_5540925_6	1396141.BATP01000059_gene2441	5.627e-49	179.0	COG5620@1|root,COG5620@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1851,GAD-like
CH3_k127_5540925_10	1396141.BATP01000059_gene2442	1.962e-17	88.0	COG5620@1|root,COG5620@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1851,GAD-like
CH3_k127_5540925_1	402777.KB235903_gene711	9.225e-128	421.0	COG0500@1|root,COG0500@2|Bacteria,1GHCT@1117|Cyanobacteria,1HHS8@1150|Oscillatoriales	1117|Cyanobacteria	Q	Putative zinc binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_13,Methyltransf_14,Methyltransf_23
CH3_k127_5540925_5	452637.Oter_4241	3.002e-49	188.0	COG0805@1|root,COG0805@2|Bacteria,46T26@74201|Verrucomicrobia,3K8EP@414999|Opitutae	414999|Opitutae	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
CH3_k127_5540925_11	290315.Clim_0624	5.313e-14	75.0	COG1826@1|root,COG1826@2|Bacteria,1FE6Y@1090|Chlorobi	1090|Chlorobi	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
CH3_k127_5540925_7	481448.Minf_2453	2.38e-30	127.0	COG2885@1|root,COG2885@2|Bacteria,46T4D@74201|Verrucomicrobia,37GNQ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	OmpA family	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
CH3_k127_5555889_10	1191299.AJYX01000045_gene214	1.229e-07	53.0	2DPM9@1|root,332MQ@2|Bacteria,1NAPW@1224|Proteobacteria,1SDC6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_5555889_11	1123405.AUMM01000031_gene1488	6.446e-05	47.0	2DTS4@1|root,33MFD@2|Bacteria,1VKHK@1239|Firmicutes,4I120@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_5555889_7	933262.AXAM01000042_gene1817	4.387e-27	124.0	COG1555@1|root,COG3156@1|root,COG1555@2|Bacteria,COG3156@2|Bacteria,1PQMW@1224|Proteobacteria,42T9B@68525|delta/epsilon subdivisions,2WPYT@28221|Deltaproteobacteria,2MKAN@213118|Desulfobacterales	28221|Deltaproteobacteria	LU	Type II secretion system (T2SS), protein K	-	-	-	ko:K02460	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSK
CH3_k127_5555889_9	1385517.N800_00590	6.5e-08	63.0	COG4795@1|root,COG4795@2|Bacteria,1MYPS@1224|Proteobacteria,1SHGQ@1236|Gammaproteobacteria,1X6ZS@135614|Xanthomonadales	135614|Xanthomonadales	U	General secretion pathway protein	xpsJ	-	-	ko:K02459	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
CH3_k127_5555889_13	1144342.PMI40_00304	0.0002146	51.0	COG4970@1|root,COG4970@2|Bacteria,1NGHS@1224|Proteobacteria,2WCQV@28216|Betaproteobacteria,474MH@75682|Oxalobacteraceae	28216|Betaproteobacteria	NU	Type II transport protein GspH	fimT	-	-	ko:K08084	-	-	-	-	ko00000,ko02044	3.A.15.2	-	-	GspH,N_methyl
CH3_k127_5555889_5	1297742.A176_06707	7.961e-73	261.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42MH9@68525|delta/epsilon subdivisions,2WJE0@28221|Deltaproteobacteria,2YTZT@29|Myxococcales	28221|Deltaproteobacteria	U	General secretion pathway protein F	gspF	-	-	ko:K02455,ko:K02653	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
CH3_k127_5555889_4	485913.Krac_6839	8.978e-74	259.0	COG1606@1|root,COG1606@2|Bacteria,2G6AU@200795|Chloroflexi	200795|Chloroflexi	L	tRNA processing	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	Asn_synthase,NAD_synthase
CH3_k127_5555889_3	385682.AFSL01000012_gene2848	5.525e-124	418.0	COG3401@1|root,COG3401@2|Bacteria,4NFM5@976|Bacteroidetes,2FPSM@200643|Bacteroidia	976|Bacteroidetes	S	candidate rhamnogalacturonan lyase, polysaccharide lyase family 11 protein K01238	-	-	4.2.2.23	ko:K18197	-	-	-	-	ko00000,ko01000	-	PL11	-	-
CH3_k127_5555889_1	266265.Bxe_B2149	1.82e-191	612.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2VHNV@28216|Betaproteobacteria,1JZMS@119060|Burkholderiaceae	28216|Betaproteobacteria	C	belongs to the aldehyde dehydrogenase family	aldH	-	1.2.1.3,1.2.1.39,1.2.1.8	ko:K00128,ko:K00130,ko:K00146	ko00010,ko00053,ko00071,ko00260,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00260,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	M00135,M00555	R00264,R00631,R00710,R00904,R01752,R01986,R02536,R02549,R02565,R02566,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CH3_k127_5555889_0	234267.Acid_4168	6.923e-194	620.0	COG2204@1|root,COG2204@2|Bacteria,3Y33M@57723|Acidobacteria	57723|Acidobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
CH3_k127_5555889_2	234267.Acid_4169	8.221e-163	524.0	COG5000@1|root,COG5000@2|Bacteria,3Y2TD@57723|Acidobacteria	57723|Acidobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
CH3_k127_5555889_6	177439.DP2557	8.509e-35	145.0	2EVII@1|root,33NYR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_5555889_8	177439.DP2558	9.066e-14	75.0	COG0419@1|root,COG0419@2|Bacteria	2|Bacteria	L	ATPase involved in DNA repair	-	-	-	ko:K02057,ko:K07459,ko:K10110	ko02010,map02010	M00194,M00221	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.1,3.A.1.1.22,3.A.1.2	-	-	AAA_11,AAA_12,AAA_13,AAA_23
CH3_k127_5567377_12	1347342.BN863_880	8.497e-44	161.0	COG0370@1|root,COG0370@2|Bacteria,4NGRN@976|Bacteroidetes,1I03Y@117743|Flavobacteriia	976|Bacteroidetes	P	transporter of a GTP-driven Fe(2 ) uptake system	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
CH3_k127_5567377_6	1396418.BATQ01000025_gene5262	3.776e-109	367.0	COG0520@1|root,COG0520@2|Bacteria,46SC0@74201|Verrucomicrobia,2IW1B@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
CH3_k127_5567377_8	240016.ABIZ01000001_gene4452	5.772e-105	350.0	COG1577@1|root,COG1577@2|Bacteria,46V85@74201|Verrucomicrobia	74201|Verrucomicrobia	I	mevalonate kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	GHMP_kinases_C,GHMP_kinases_N
CH3_k127_5567377_9	234267.Acid_7362	7.727e-94	317.0	COG1210@1|root,COG1210@2|Bacteria,3Y39W@57723|Acidobacteria	2|Bacteria	M	PFAM Nucleotidyl transferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP0646	NTP_transferase
CH3_k127_5567377_14	290397.Adeh_3736	1.758e-10	66.0	COG0296@1|root,COG0296@2|Bacteria	2|Bacteria	G	1,4-alpha-glucan branching enzyme activity	-	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	AMPK1_CBM,Alpha-amylase,Alpha-amylase_C,CBM_48
CH3_k127_5567377_10	497964.CfE428DRAFT_0566	2.672e-62	218.0	COG0590@1|root,COG0590@2|Bacteria,46SZZ@74201|Verrucomicrobia	74201|Verrucomicrobia	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
CH3_k127_5567377_17	871585.BDGL_001653	3.698e-05	55.0	COG1714@1|root,COG1714@2|Bacteria,1NB1Z@1224|Proteobacteria,1S5BT@1236|Gammaproteobacteria,3NK23@468|Moraxellaceae	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4339,RDD
CH3_k127_5567377_5	1337936.IJ00_09705	2.781e-115	387.0	COG0477@1|root,COG0477@2|Bacteria,1G1NG@1117|Cyanobacteria,1HKZ8@1161|Nostocales	1117|Cyanobacteria	EGP	major facilitator superfamily MFS_1	-	-	-	ko:K08225	-	-	-	-	ko00000,ko02000	2.A.1.38	-	-	MFS_3
CH3_k127_5567377_7	1396418.BATQ01000133_gene4024	2.744e-108	359.0	COG1801@1|root,COG1801@2|Bacteria,46TUG@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
CH3_k127_5567377_4	497964.CfE428DRAFT_5147	3.956e-121	409.0	COG1752@1|root,COG1752@2|Bacteria	2|Bacteria	M	Esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
CH3_k127_5567377_1	497964.CfE428DRAFT_5146	2.764e-179	575.0	COG1541@1|root,COG1541@2|Bacteria,46UTU@74201|Verrucomicrobia	74201|Verrucomicrobia	H	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
CH3_k127_5567377_13	391625.PPSIR1_04398	4.207e-30	125.0	COG1607@1|root,COG1607@2|Bacteria,1MZAZ@1224|Proteobacteria,42RJS@68525|delta/epsilon subdivisions,2WQSB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Thioesterase superfamily	yciA	-	-	ko:K10806	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT
CH3_k127_5567377_0	1267535.KB906767_gene933	6.533e-201	636.0	COG3669@1|root,COG3669@2|Bacteria,3Y37T@57723|Acidobacteria,2JKVF@204432|Acidobacteriia	204432|Acidobacteriia	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,F5_F8_type_C
CH3_k127_5567377_3	240016.ABIZ01000001_gene2328	3.208e-124	411.0	COG0141@1|root,COG0141@2|Bacteria,46SHG@74201|Verrucomicrobia,2ITG9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
CH3_k127_5567377_11	452637.Oter_2441	6.927e-60	216.0	COG0284@1|root,COG0284@2|Bacteria,46T17@74201|Verrucomicrobia,3K7VT@414999|Opitutae	414999|Opitutae	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
CH3_k127_5567377_2	1403819.BATR01000044_gene1265	8.216e-149	483.0	COG2204@1|root,COG2204@2|Bacteria,46SFE@74201|Verrucomicrobia,2ITIG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
CH3_k127_5567377_16	497964.CfE428DRAFT_3286	1.79e-05	53.0	COG1928@1|root,COG1928@2|Bacteria,46UW1@74201|Verrucomicrobia	74201|Verrucomicrobia	O	C-terminal four TMM region of protein-O-mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_5595605_0	243233.MCA2161	2.548e-168	553.0	COG3206@1|root,COG3206@2|Bacteria,1QX0J@1224|Proteobacteria,1RZ5A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	protein involved in exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_5595605_1	1040989.AWZU01000025_gene6324	2.677e-16	87.0	COG2335@1|root,COG2335@2|Bacteria,1MZ8G@1224|Proteobacteria,2U5ZN@28211|Alphaproteobacteria,3JY4R@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	A domain in the BMP inhibitor chordin and in microbial proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
CH3_k127_5603385_3	935948.KE386494_gene686	8.542e-70	245.0	COG3533@1|root,COG3533@2|Bacteria,1TNYA@1239|Firmicutes,24841@186801|Clostridia,42FR7@68295|Thermoanaerobacterales	186801|Clostridia	S	Beta-L-arabinofuranosidase, GH127	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
CH3_k127_5603385_0	926569.ANT_13690	4.898e-207	654.0	COG2407@1|root,COG2407@2|Bacteria,2G84V@200795|Chloroflexi	200795|Chloroflexi	G	L-fucose isomerase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Fucose_iso_C
CH3_k127_5603385_1	237368.SCABRO_00906	3.537e-110	377.0	COG0612@1|root,COG0612@2|Bacteria,2IYKK@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
CH3_k127_5603385_2	247490.KSU1_D0861	1.623e-87	307.0	COG0612@1|root,COG0612@2|Bacteria,2IYKK@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Peptidase M16 inactive domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
CH3_k127_5603385_5	533247.CRD_00325	2.954e-17	98.0	COG2303@1|root,COG2931@1|root,COG2303@2|Bacteria,COG2931@2|Bacteria,1G31H@1117|Cyanobacteria,1HKAQ@1161|Nostocales	1117|Cyanobacteria	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,GIDA,GMC_oxred_C,GMC_oxred_N,NAD_binding_8
CH3_k127_5603385_4	1121373.KB903625_gene3160	1.365e-51	211.0	COG2972@1|root,COG3292@1|root,COG2972@2|Bacteria,COG3292@2|Bacteria,4PMED@976|Bacteroidetes,47Y31@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
CH3_k127_5606537_0	497964.CfE428DRAFT_2523	0.0	1244.0	COG0209@1|root,COG0209@2|Bacteria,46SG4@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
CH3_k127_5606537_1	1081644.IMCC13023_01510	4.961e-20	96.0	COG1811@1|root,COG1811@2|Bacteria,2GM75@201174|Actinobacteria	201174|Actinobacteria	S	Na channel or pump	-	-	-	ko:K07150	-	-	-	-	ko00000	-	-	-	DUF554
CH3_k127_5673977_1	497964.CfE428DRAFT_4660	4.144e-180	575.0	COG1520@1|root,COG1520@2|Bacteria,46TSY@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CH3_k127_5673977_6	293613.A1E_02110	1.825e-11	74.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQW2@28211|Alphaproteobacteria,47EYI@766|Rickettsiales	766|Rickettsiales	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	ntrX	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CH3_k127_5673977_4	700598.Niako_1749	6.094e-61	219.0	COG3828@1|root,COG3828@2|Bacteria,4NRZF@976|Bacteroidetes,1IVGZ@117747|Sphingobacteriia	976|Bacteroidetes	S	Trehalose utilisation	-	-	-	ko:K09992	-	-	-	-	ko00000	-	-	-	ThuA
CH3_k127_5673977_7	344747.PM8797T_25596	3.762e-08	63.0	COG3137@1|root,COG3137@2|Bacteria,2J024@203682|Planctomycetes	203682|Planctomycetes	M	Protein of unknown function, DUF481	-	-	-	-	-	-	-	-	-	-	-	-	DUF481
CH3_k127_5673977_2	448385.sce7786	1.325e-153	501.0	COG3104@1|root,COG3104@2|Bacteria,1P6K2@1224|Proteobacteria	1224|Proteobacteria	E	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CH3_k127_5673977_0	886293.Sinac_5714	3.599e-246	794.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,2IYA8@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
CH3_k127_5673977_3	1121123.AUAO01000003_gene2394	1.932e-136	447.0	COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,2TR5C@28211|Alphaproteobacteria,2KIF5@204458|Caulobacterales	204458|Caulobacterales	E	Membrane dipeptidase (Peptidase family M19)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M19
CH3_k127_5673977_5	398525.KB900702_gene176	2.326e-48	184.0	COG3547@1|root,COG3547@2|Bacteria,1MUKH@1224|Proteobacteria,2TRPW@28211|Alphaproteobacteria,3JXN6@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	transposase IS116 IS110 IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
CH3_k127_5674425_0	443143.GM18_0105	1.703e-102	341.0	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,42QGH@68525|delta/epsilon subdivisions,2WKTM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	PFAM multicopper oxidase type 2	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2
CH3_k127_5674425_2	644966.Tmar_1372	5.035e-53	195.0	COG2197@1|root,COG2197@2|Bacteria,1TQ1U@1239|Firmicutes,25B1X@186801|Clostridia,3WDTH@538999|Clostridiales incertae sedis	186801|Clostridia	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K11618	ko02020,map02020	M00481,M00754	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
CH3_k127_5674425_1	768710.DesyoDRAFT_1525	4.414e-60	224.0	COG4585@1|root,COG5000@1|root,COG4585@2|Bacteria,COG5000@2|Bacteria,1TQI3@1239|Firmicutes,249R9@186801|Clostridia,2644X@186807|Peptococcaceae	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K07777	ko02020,map02020	M00478	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA_3,sCache_3_2
CH3_k127_568721_6	278957.ABEA03000015_gene3315	1.455e-17	93.0	COG0513@1|root,COG0513@2|Bacteria,46U0S@74201|Verrucomicrobia,3K72X@414999|Opitutae	414999|Opitutae	L	DEAD DEAH box helicase	-	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
CH3_k127_568721_0	497964.CfE428DRAFT_1254	0.0	1298.0	COG4581@1|root,COG4581@2|Bacteria,46STC@74201|Verrucomicrobia	74201|Verrucomicrobia	L	DEAD DEAH box helicase	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,DUF3516,Helicase_C
CH3_k127_568721_3	768710.DesyoDRAFT_1775	2.18e-133	449.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	ko:K22318	-	-	-	-	ko00000	-	-	-	B12-binding,Radical_SAM
CH3_k127_568721_1	1123070.KB899251_gene679	7.713e-193	620.0	COG0488@1|root,COG0488@2|Bacteria,46SJA@74201|Verrucomicrobia,2ITVQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	ABC transporter C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
CH3_k127_568721_2	497964.CfE428DRAFT_2915	5.639e-158	509.0	COG0541@1|root,COG0541@2|Bacteria,46SIU@74201|Verrucomicrobia	74201|Verrucomicrobia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
CH3_k127_568721_5	1499967.BAYZ01000080_gene944	7.843e-21	104.0	2DM1D@1|root,31AEB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_568721_4	1125701.HMPREF1221_01616	1.693e-41	161.0	COG2407@1|root,COG2407@2|Bacteria	2|Bacteria	G	Converts the aldose L-fucose into the corresponding ketose L-fuculose	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_5688674_1	471854.Dfer_0095	2.503e-127	419.0	COG1680@1|root,COG1680@2|Bacteria,4NGKK@976|Bacteroidetes,47N9R@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471,TPR_2
CH3_k127_5688674_2	240016.ABIZ01000001_gene2202	3.483e-105	349.0	COG1801@1|root,COG1801@2|Bacteria,46TUG@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
CH3_k127_5688674_9	497964.CfE428DRAFT_2905	2.443e-05	47.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_4,Phage_integrase
CH3_k127_5688674_5	1140.Synpcc7942_1288	3.052e-42	162.0	COG3831@1|root,COG3831@2|Bacteria,1GPKY@1117|Cyanobacteria,1H3GN@1129|Synechococcus	1117|Cyanobacteria	S	Protein of unknown function (DUF4240)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4240
CH3_k127_5688674_6	935567.JAES01000033_gene858	1.37e-20	93.0	2EK70@1|root,33DXD@2|Bacteria,1NA99@1224|Proteobacteria,1SJFZ@1236|Gammaproteobacteria,1X82Y@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_5688674_3	1403819.BATR01000104_gene3538	1.949e-87	302.0	COG3618@1|root,COG3618@2|Bacteria,46SN7@74201|Verrucomicrobia,2IUQ3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CH3_k127_5688674_4	1499967.BAYZ01000137_gene111	6.59e-51	191.0	2FGP7@1|root,348IT@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_5688674_0	886293.Sinac_7347	2.369e-146	477.0	COG3507@1|root,COG3507@2|Bacteria,2J27X@203682|Planctomycetes	203682|Planctomycetes	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_5688674_7	552398.HMPREF0866_03064	1.844e-18	88.0	2ED8C@1|root,3374X@2|Bacteria,1W0C5@1239|Firmicutes,24S5N@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Smr
CH3_k127_5702607_1	330214.NIDE0577	1.826e-311	976.0	COG0433@1|root,COG0433@2|Bacteria	2|Bacteria	S	helicase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF853,DUF87
CH3_k127_5702607_11	497964.CfE428DRAFT_0115	2.924e-94	314.0	COG0177@1|root,COG0177@2|Bacteria,46T2G@74201|Verrucomicrobia	74201|Verrucomicrobia	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
CH3_k127_5702607_18	481448.Minf_1759	1.273e-32	136.0	COG0095@1|root,COG0095@2|Bacteria,46T01@74201|Verrucomicrobia,37GRJ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	H	Biotin/lipoate A/B protein ligase family	lplA	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
CH3_k127_5702607_20	661367.LLO_1892	3.979e-13	83.0	COG3250@1|root,COG4733@1|root,COG5492@1|root,COG3250@2|Bacteria,COG4733@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Malectin,fn3
CH3_k127_5702607_0	481448.Minf_1559	0.0	1150.0	COG0653@1|root,COG0653@2|Bacteria,46SJC@74201|Verrucomicrobia,37G1Y@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
CH3_k127_5702607_7	1396141.BATP01000061_gene4541	9.845e-129	426.0	28N64@1|root,2ZBFG@2|Bacteria,46Z9S@74201|Verrucomicrobia,2IWQS@203494|Verrucomicrobiae	2|Bacteria	S	Peptidase of plants and bacteria	-	-	-	-	-	-	-	-	-	-	-	-	BSP
CH3_k127_5702607_6	247490.KSU1_D0782	6.716e-130	432.0	COG3170@1|root,COG3170@2|Bacteria,2J3MN@203682|Planctomycetes	203682|Planctomycetes	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_5702607_13	247490.KSU1_D0783	3.627e-84	292.0	COG0803@1|root,COG0803@2|Bacteria,2J0IP@203682|Planctomycetes	203682|Planctomycetes	P	Zinc-uptake complex component A periplasmic	-	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
CH3_k127_5702607_14	1379698.RBG1_1C00001G0109	7.825e-71	248.0	COG1108@1|root,COG1108@2|Bacteria,2NQ6F@2323|unclassified Bacteria	2|Bacteria	U	ABC 3 transport family	znuB	-	-	ko:K02075,ko:K09816	ko02010,map02010	M00242,M00244	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
CH3_k127_5702607_3	886293.Sinac_5129	2.532e-218	685.0	COG4948@1|root,COG4948@2|Bacteria,2IXK2@203682|Planctomycetes	203682|Planctomycetes	M	Belongs to the mandelate racemase muconate lactonizing enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C
CH3_k127_5702607_5	497964.CfE428DRAFT_3487	4.619e-137	475.0	COG4191@1|root,COG4191@2|Bacteria,46TV0@74201|Verrucomicrobia	74201|Verrucomicrobia	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,Response_reg
CH3_k127_5702607_19	478741.JAFS01000002_gene252	1.473e-13	77.0	COG1366@1|root,COG1366@2|Bacteria,46T4Z@74201|Verrucomicrobia,37GXU@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	T	STAS domain	rsbS	-	-	-	-	-	-	-	-	-	-	-	STAS
CH3_k127_5702607_17	240016.ABIZ01000001_gene908	9.034e-40	163.0	COG1466@1|root,COG1466@2|Bacteria,46T5Y@74201|Verrucomicrobia,2ITP3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
CH3_k127_5702607_16	1156937.MFUM_920008	6.231e-48	175.0	COG1259@1|root,COG1259@2|Bacteria,46SW6@74201|Verrucomicrobia,37GI8@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
CH3_k127_5702607_12	641524.ADICYQ_2355	1.916e-93	330.0	COG4403@1|root,COG4403@2|Bacteria,4PMC1@976|Bacteroidetes,47Y49@768503|Cytophagia	976|Bacteroidetes	V	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
CH3_k127_5702607_15	1267535.KB906767_gene1118	1.439e-68	242.0	COG3279@1|root,COG3279@2|Bacteria,3Y4VI@57723|Acidobacteria,2JJIJ@204432|Acidobacteriia	204432|Acidobacteriia	T	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
CH3_k127_5702607_9	382464.ABSI01000011_gene2813	1.983e-107	359.0	COG2972@1|root,COG2972@2|Bacteria,46TY3@74201|Verrucomicrobia,2IVUC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
CH3_k127_5702607_4	243090.RB11088	1.035e-199	639.0	COG0457@1|root,COG0457@2|Bacteria,2IYBX@203682|Planctomycetes	203682|Planctomycetes	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
CH3_k127_5702607_2	452637.Oter_2956	4.477e-226	711.0	COG0367@1|root,COG0367@2|Bacteria	2|Bacteria	E	asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase
CH3_k127_5702607_8	452637.Oter_2957	2.037e-117	387.0	COG1244@1|root,COG1244@2|Bacteria	2|Bacteria	S	Elongator protein 3, MiaB family, Radical SAM	-	-	-	ko:K06936	-	-	-	-	ko00000	-	-	-	-
CH3_k127_5702607_10	1396141.BATP01000021_gene180	2.053e-100	359.0	COG0515@1|root,COG0515@2|Bacteria	1396141.BATP01000021_gene180|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_5743333_0	886293.Sinac_0918	1.183e-173	560.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C,TAT_signal
CH3_k127_5743333_1	497964.CfE428DRAFT_4863	3.793e-110	380.0	COG0515@1|root,COG0515@2|Bacteria	497964.CfE428DRAFT_4863|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_5743333_2	497964.CfE428DRAFT_4864	6.652e-77	266.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_5743333_3	35754.JNYJ01000002_gene6868	1.009e-31	130.0	COG1874@1|root,COG1874@2|Bacteria,2GNR4@201174|Actinobacteria,4DC36@85008|Micromonosporales	201174|Actinobacteria	G	Domain of unknown function (DUF4832)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4832
CH3_k127_5767152_9	428125.CLOLEP_03042	2.229e-79	278.0	COG3693@1|root,COG3693@2|Bacteria,1UZWX@1239|Firmicutes,24BPR@186801|Clostridia	186801|Clostridia	G	PFAM glycoside hydrolase, family 10	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_10
CH3_k127_5767152_18	1219084.AP014508_gene1338	1.081e-14	91.0	COG0745@1|root,COG0745@2|Bacteria,2GDAM@200918|Thermotogae	200918|Thermotogae	T	PFAM response regulator receiver	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
CH3_k127_5767152_17	497964.CfE428DRAFT_5353	3.573e-20	109.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,HATPase_c,HD_5,Response_reg,T2SSE_N
CH3_k127_5767152_22	1158146.KB907123_gene599	0.0009561	48.0	COG1444@1|root,COG1444@2|Bacteria,1NBA4@1224|Proteobacteria,1RPAM@1236|Gammaproteobacteria,1WWJD@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP)	tmcA	-	2.3.1.193	ko:K06957	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1726,GNAT_acetyltr_2,Helicase_RecD,tRNA_bind_3
CH3_k127_5767152_12	1410620.SHLA_36c000140	4.438e-61	222.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CH3_k127_5767152_8	234267.Acid_0753	4.937e-83	290.0	COG0673@1|root,COG0673@2|Bacteria,3Y4KS@57723|Acidobacteria	57723|Acidobacteria	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CH3_k127_5767152_3	518766.Rmar_1439	1.564e-235	749.0	COG0457@1|root,COG0457@2|Bacteria	518766.Rmar_1439|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_5767152_5	518766.Rmar_1438	4.036e-135	462.0	COG0457@1|root,COG0457@2|Bacteria	518766.Rmar_1438|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_5767152_16	1541065.JRFE01000058_gene5541	5.331e-22	104.0	2DBIE@1|root,32ZYG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_5767152_20	1121406.JAEX01000009_gene2643	3.715e-06	59.0	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,42QZ1@68525|delta/epsilon subdivisions,2WKYF@28221|Deltaproteobacteria,2MA59@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
CH3_k127_5767152_10	335543.Sfum_1620	1.401e-75	271.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
CH3_k127_5767152_11	234267.Acid_6081	4.599e-71	254.0	COG3292@1|root,COG3292@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_3,HATPase_c,PKD_3,Reg_prop
CH3_k127_5767152_6	335543.Sfum_1622	1.083e-128	438.0	COG1858@1|root,COG3391@1|root,COG1858@2|Bacteria,COG3391@2|Bacteria,1R7E0@1224|Proteobacteria,42XD8@68525|delta/epsilon subdivisions,2WT8U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM 40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_C554
CH3_k127_5767152_13	234267.Acid_6078	1.007e-35	153.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,PD40,SdrD_B
CH3_k127_5767152_4	452637.Oter_2942	2.201e-202	648.0	COG3118@1|root,COG3118@2|Bacteria	2|Bacteria	O	belongs to the thioredoxin family	ybbN	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K03671,ko:K05838	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
CH3_k127_5767152_14	580331.Thit_1725	7.866e-32	145.0	COG0412@1|root,COG0412@2|Bacteria,1TQQS@1239|Firmicutes,24DCW@186801|Clostridia,42FHF@68295|Thermoanaerobacterales	186801|Clostridia	Q	Abhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_7,BAAT_C
CH3_k127_5767152_7	1288963.ADIS_1386	4.322e-103	369.0	28HHT@1|root,2Z7TE@2|Bacteria,4NIHS@976|Bacteroidetes,47MAA@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_5767152_1	861299.J421_1753	9.439e-294	943.0	COG0446@1|root,COG4888@1|root,COG0446@2|Bacteria,COG4888@2|Bacteria	2|Bacteria	G	ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,Pyr_redox_2,UnbV_ASPIC,VCBS
CH3_k127_5767152_2	861299.J421_1753	9.264e-290	933.0	COG0446@1|root,COG4888@1|root,COG0446@2|Bacteria,COG4888@2|Bacteria	2|Bacteria	G	ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,Pyr_redox_2,UnbV_ASPIC,VCBS
CH3_k127_5767152_21	1403819.BATR01000069_gene2031	9.896e-06	59.0	COG1470@1|root,COG1749@1|root,COG3291@1|root,COG3506@1|root,COG3533@1|root,COG1470@2|Bacteria,COG1749@2|Bacteria,COG3291@2|Bacteria,COG3506@2|Bacteria,COG3533@2|Bacteria,46SQ1@74201|Verrucomicrobia,2IV3A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	N	Erythromycin esterase	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_5767152_19	324057.Pjdr2_2563	7.648e-09	70.0	COG4447@1|root,COG4733@1|root,COG5297@1|root,COG4447@2|Bacteria,COG4733@2|Bacteria,COG5297@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase family 6	dex	-	3.2.1.11	ko:K05988,ko:K06882	ko00500,map00500	-	R11309	-	ko00000,ko00001,ko01000	-	GH66	-	fn3
CH3_k127_5767152_0	452637.Oter_2954	0.0	1242.0	COG0457@1|root,COG0457@2|Bacteria	452637.Oter_2954|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_5767152_15	1255043.TVNIR_1306	1e-28	117.0	COG3118@1|root,COG3118@2|Bacteria	2|Bacteria	O	belongs to the thioredoxin family	ybbN	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K03671,ko:K05838	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
CH3_k127_5790492_7	1123242.JH636434_gene4307	7.981e-12	68.0	COG1032@1|root,COG1032@2|Bacteria,2J1W3@203682|Planctomycetes	203682|Planctomycetes	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4080,Radical_SAM
CH3_k127_5790492_4	313628.LNTAR_18430	2.138e-28	120.0	COG1372@1|root,COG1372@2|Bacteria	2|Bacteria	L	intein-mediated protein splicing	-	-	1.1.98.6,3.6.3.14,3.6.3.15,4.1.1.35	ko:K02117,ko:K08678,ko:K21636	ko00190,ko00230,ko00240,ko00520,ko01100,map00190,map00230,map00240,map00520,map01100	M00053,M00159,M00361	R01384,R11633,R11634,R11635,R11636	RC00508,RC00613	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-cone,DUF4280,Intein_splicing,LAGLIDADG_3,NRDD,PT-HINT
CH3_k127_5790492_2	765420.OSCT_3130	2.06e-67	245.0	COG4932@1|root,COG5184@1|root,COG4932@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	ychO	GO:0005575,GO:0005623,GO:0008150,GO:0009279,GO:0009405,GO:0016020,GO:0019867,GO:0030260,GO:0030312,GO:0030313,GO:0031975,GO:0044403,GO:0044409,GO:0044419,GO:0044462,GO:0044464,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0071944	3.2.1.14	ko:K01183,ko:K20276	ko00520,ko01100,ko02024,map00520,map01100,map02024	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	He_PIG,IAT_beta,RCC1_2
CH3_k127_5790492_6	113355.CM001775_gene3666	9.069e-14	84.0	COG1404@1|root,COG1404@2|Bacteria,1G1G8@1117|Cyanobacteria	1117|Cyanobacteria	O	Subtilisin-like serine protease	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
CH3_k127_5790492_3	261292.Nit79A3_1788	9.597e-33	148.0	28HU5@1|root,2Z80X@2|Bacteria,1R55N@1224|Proteobacteria,2VI32@28216|Betaproteobacteria,372Y4@32003|Nitrosomonadales	28216|Betaproteobacteria	S	TIGRFAM TIGR03790 family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_5790492_0	1396141.BATP01000032_gene4274	7.581e-215	687.0	COG1073@1|root,COG1073@2|Bacteria,46Z70@74201|Verrucomicrobia,2IWQ7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	AXE1
CH3_k127_5790492_1	497964.CfE428DRAFT_3901	2.315e-87	295.0	COG0210@1|root,COG0210@2|Bacteria,46S8H@74201|Verrucomicrobia	74201|Verrucomicrobia	L	PFAM UvrD REP helicase	uvrD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
CH3_k127_5884056_3	661478.OP10G_1795	3.894e-15	86.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02650,ko:K02679	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10
CH3_k127_5884056_0	497964.CfE428DRAFT_2397	3.365e-117	386.0	COG1858@1|root,COG1858@2|Bacteria,46SJU@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Di-haem cytochrome c peroxidase	mauG	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
CH3_k127_5884056_1	497964.CfE428DRAFT_1756	1.253e-72	259.0	COG2207@1|root,COG2207@2|Bacteria,46T4M@74201|Verrucomicrobia	74201|Verrucomicrobia	K	helix_turn_helix, arabinose operon control protein	araC	-	-	-	-	-	-	-	-	-	-	-	HTH_18
CH3_k127_5884056_2	794903.OPIT5_03260	3.837e-22	108.0	COG4783@1|root,COG4783@2|Bacteria,46TAI@74201|Verrucomicrobia,3K7ZQ@414999|Opitutae	414999|Opitutae	S	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_5884056_4	870187.Thini_4435	2.055e-05	55.0	28XJT@1|root,2ZJGX@2|Bacteria,1P89B@1224|Proteobacteria,1SWA4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_590947_0	1291050.JAGE01000001_gene867	9.973e-175	574.0	COG0823@1|root,COG0823@2|Bacteria,1VP24@1239|Firmicutes,24WTQ@186801|Clostridia,3WN5Z@541000|Ruminococcaceae	186801|Clostridia	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
CH3_k127_590947_1	583355.Caka_3039	5.501e-161	527.0	COG1858@1|root,COG3391@1|root,COG1858@2|Bacteria,COG3391@2|Bacteria,46UC1@74201|Verrucomicrobia,3K9FB@414999|Opitutae	414999|Opitutae	C	TIGRFAM 40-residue YVTN family beta-propeller repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_5911469_0	742725.HMPREF9450_01532	5.618e-148	492.0	COG3420@1|root,COG3420@2|Bacteria,4PMG9@976|Bacteroidetes,2FQGR@200643|Bacteroidia	976|Bacteroidetes	P	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
CH3_k127_5911469_1	1316936.K678_06250	3.694e-64	229.0	COG5266@1|root,COG5266@2|Bacteria,1PVKN@1224|Proteobacteria,2TU9S@28211|Alphaproteobacteria,2JPEY@204441|Rhodospirillales	204441|Rhodospirillales	P	ABC-type Co2 transport system, periplasmic component	-	-	-	ko:K02009	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18	-	-	DUF4198
CH3_k127_5911469_2	383372.Rcas_2444	4.256e-24	120.0	2DQ8H@1|root,335A3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_5916708_4	886293.Sinac_0402	1.926e-101	353.0	COG1196@1|root,COG1196@2|Bacteria,2IYCW@203682|Planctomycetes	203682|Planctomycetes	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_5916708_0	1123242.JH636434_gene3690	2.057e-222	715.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,2IWWQ@203682|Planctomycetes	203682|Planctomycetes	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	GATase1_like
CH3_k127_5916708_3	886293.Sinac_0400	4.341e-103	354.0	COG4249@1|root,COG4249@2|Bacteria,2IZ2A@203682|Planctomycetes	203682|Planctomycetes	S	Peptidase C14 caspase catalytic subunit p20	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_5916708_1	330214.NIDE3012	2.15e-159	511.0	COG1089@1|root,COG1089@2|Bacteria,3J0YR@40117|Nitrospirae	40117|Nitrospirae	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
CH3_k127_5916708_2	1123277.KB893193_gene3895	1.461e-129	423.0	COG0451@1|root,COG0451@2|Bacteria,4NDV4@976|Bacteroidetes,47KAF@768503|Cytophagia	976|Bacteroidetes	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
CH3_k127_5916708_5	497964.CfE428DRAFT_4965	1.184e-17	87.0	COG2165@1|root,COG2165@2|Bacteria,46T8M@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
CH3_k127_592804_6	1396141.BATP01000022_gene421	1.018e-57	214.0	2BVGP@1|root,32QVG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_592804_1	1123508.JH636439_gene1370	3.713e-193	622.0	COG1073@1|root,COG1073@2|Bacteria,2IWSQ@203682|Planctomycetes	203682|Planctomycetes	S	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
CH3_k127_592804_0	497964.CfE428DRAFT_1053	3.886e-236	744.0	COG1574@1|root,COG1574@2|Bacteria,46V0N@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
CH3_k127_592804_7	344747.PM8797T_14579	3.447e-49	180.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CH3_k127_592804_4	1097668.BYI23_C006580	1.594e-93	323.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	msrB	-	1.8.4.11,1.8.4.12	ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA,PMSR,Redoxin,SelR,Thioredoxin
CH3_k127_592804_2	1396141.BATP01000060_gene4560	1.437e-170	584.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,46UAE@74201|Verrucomicrobia,2IV44@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_12,WD40
CH3_k127_592804_5	1123242.JH636435_gene2613	3.537e-60	216.0	COG1595@1|root,COG1595@2|Bacteria,2IZZP@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
CH3_k127_592804_3	1123242.JH636434_gene3764	3.842e-96	326.0	COG0673@1|root,COG0673@2|Bacteria,2IXJ0@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CH3_k127_5945347_0	794903.OPIT5_16410	0.0	1414.0	COG3696@1|root,COG3696@2|Bacteria,46SJ1@74201|Verrucomicrobia,3K7EV@414999|Opitutae	414999|Opitutae	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
CH3_k127_5945347_2	452637.Oter_2746	5.351e-132	439.0	COG1249@1|root,COG1249@2|Bacteria,46S8I@74201|Verrucomicrobia,3K7TS@414999|Opitutae	414999|Opitutae	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
CH3_k127_5945347_1	314230.DSM3645_06639	1.408e-173	554.0	COG2609@1|root,COG2609@2|Bacteria,2IXXY@203682|Planctomycetes	203682|Planctomycetes	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
CH3_k127_594624_4	443143.GM18_3048	2.548e-94	314.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,42M7A@68525|delta/epsilon subdivisions,2WJ8P@28221|Deltaproteobacteria,43TAZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	PFAM glutamine synthetase catalytic region	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
CH3_k127_594624_3	1396418.BATQ01000106_gene5285	5.126e-170	548.0	COG0004@1|root,COG0004@2|Bacteria,46SCE@74201|Verrucomicrobia,2ITWC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Ammonium Transporter Family	-	-	-	-	-	-	-	-	-	-	-	-	Ammonium_transp
CH3_k127_594624_8	497964.CfE428DRAFT_6239	2.161e-49	178.0	COG0347@1|root,COG0347@2|Bacteria,46VXS@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Belongs to the P(II) protein family	-	-	-	-	-	-	-	-	-	-	-	-	P-II
CH3_k127_594624_1	497964.CfE428DRAFT_0232	1.855e-215	686.0	COG0531@1|root,COG0531@2|Bacteria	2|Bacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_594624_13	1121887.AUDK01000010_gene1434	1.403e-05	53.0	2DP52@1|root,330JK@2|Bacteria,4NUTX@976|Bacteroidetes,1I5F0@117743|Flavobacteriia,2NWA6@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_594624_5	309807.SRU_2450	8.605e-91	319.0	COG1785@1|root,COG1785@2|Bacteria,4NG3D@976|Bacteroidetes,1FIWB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	Belongs to the alkaline phosphatase family	-	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase
CH3_k127_594624_10	886293.Sinac_3363	4.351e-27	124.0	COG4299@1|root,COG4299@2|Bacteria,2IYKU@203682|Planctomycetes	203682|Planctomycetes	S	COGs COG4299 conserved	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
CH3_k127_594624_9	1294143.H681_11855	3.414e-30	134.0	COG1538@1|root,COG1538@2|Bacteria,1NEZC@1224|Proteobacteria,1RZB6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	MU	COG1538 Outer membrane protein	czcC	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
CH3_k127_594624_0	404589.Anae109_4094	0.0	1177.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42M0A@68525|delta/epsilon subdivisions,2WIQY@28221|Deltaproteobacteria,2YTXB@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
CH3_k127_594624_6	768671.ThimaDRAFT_4573	4.16e-74	269.0	COG0845@1|root,COG0845@2|Bacteria,1PQHB@1224|Proteobacteria,1T9ZT@1236|Gammaproteobacteria,1WYMB@135613|Chromatiales	135613|Chromatiales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3,HlyD_D23
CH3_k127_594624_12	1172180.KB911792_gene3761	1.269e-15	83.0	COG0680@1|root,COG0680@2|Bacteria,2IJ3P@201174|Actinobacteria	201174|Actinobacteria	C	Hydrogenase maturation protease	-	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
CH3_k127_594624_2	518766.Rmar_2590	1.28e-173	555.0	COG3259@1|root,COG3259@2|Bacteria	2|Bacteria	C	Nickel-dependent hydrogenase	hoxH	-	1.12.1.2	ko:K00436	-	-	R00700	-	ko00000,ko01000	-	-	-	NiFeSe_Hases
CH3_k127_594624_7	926550.CLDAP_19250	7.567e-63	220.0	COG1941@1|root,COG1941@2|Bacteria,2G8TW@200795|Chloroflexi	200795|Chloroflexi	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q6
CH3_k127_5964870_9	1123035.ARLA01000026_gene170	0.0004358	51.0	COG0793@1|root,COG0793@2|Bacteria,4NIGU@976|Bacteroidetes,1I43H@117743|Flavobacteriia	976|Bacteroidetes	M	Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
CH3_k127_5964870_6	1122165.AUHS01000032_gene2254	4.412e-23	112.0	2CIHU@1|root,338F9@2|Bacteria,1NES4@1224|Proteobacteria,1STBF@1236|Gammaproteobacteria,1JD5H@118969|Legionellales	118969|Legionellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_5964870_1	589865.DaAHT2_0221	5.605e-91	312.0	COG2172@1|root,COG2208@1|root,COG5002@1|root,COG2172@2|Bacteria,COG2208@2|Bacteria,COG5002@2|Bacteria,1PGCN@1224|Proteobacteria,42ZJ2@68525|delta/epsilon subdivisions,2WUYN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM Stage II sporulation E family protein	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
CH3_k127_5964870_0	330214.NIDE3482	7.66e-220	687.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR
CH3_k127_5964870_5	497964.CfE428DRAFT_3867	4.414e-42	156.0	COG1977@1|root,COG1977@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	-	-	2.7.7.80,2.8.1.11	ko:K03636,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiS
CH3_k127_5964870_2	298654.FraEuI1c_4826	2.308e-61	230.0	COG2234@1|root,COG2234@2|Bacteria,2GJ67@201174|Actinobacteria	201174|Actinobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
CH3_k127_5964870_8	794903.OPIT5_14770	5.094e-14	82.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
CH3_k127_5964870_4	497964.CfE428DRAFT_3172	1.796e-44	166.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	yitI	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
CH3_k127_5964870_3	743721.Psesu_2584	1.996e-46	168.0	COG2382@1|root,COG2382@2|Bacteria,1NFUS@1224|Proteobacteria,1T816@1236|Gammaproteobacteria,1XA10@135614|Xanthomonadales	135614|Xanthomonadales	P	Putative esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase
CH3_k127_5999671_1	497964.CfE428DRAFT_4707	3.218e-79	271.0	COG1060@1|root,COG1060@2|Bacteria	2|Bacteria	H	7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity	mqnC	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188	1.21.98.1,2.5.1.77	ko:K11779,ko:K11780,ko:K11781,ko:K11784	ko00130,ko00680,ko01110,ko01120,map00130,map00680,map01110,map01120	M00378	R08588,R09396	RC01381,RC02329,RC03002,RC03007	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
CH3_k127_5999671_0	65093.PCC7418_0570	4.14e-196	682.0	COG5276@1|root,COG5276@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,Pesticin,RHS_repeat
CH3_k127_6026449_10	1121440.AUMA01000005_gene2575	1.096e-80	281.0	COG0451@1|root,COG0451@2|Bacteria,1PB4Y@1224|Proteobacteria,42QBV@68525|delta/epsilon subdivisions,2WQ8F@28221|Deltaproteobacteria,2MB41@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
CH3_k127_6026449_2	402777.KB235904_gene3439	6.394e-135	446.0	COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1G2IU@1117|Cyanobacteria	1117|Cyanobacteria	M	TIGRFAM rfaE bifunctional protein, domain I	rfaE	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like,PfkB
CH3_k127_6026449_7	614083.AWQR01000023_gene151	1.051e-102	344.0	COG1062@1|root,COG1062@2|Bacteria	2|Bacteria	C	S-(hydroxymethyl)glutathione dehydrogenase activity	-	-	1.1.1.1,1.1.1.284	ko:K00001,ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CH3_k127_6026449_3	1121033.AUCF01000009_gene1174	8.43e-133	428.0	COG3959@1|root,COG3959@2|Bacteria,1MWRX@1224|Proteobacteria,2TRA2@28211|Alphaproteobacteria,2JSGM@204441|Rhodospirillales	204441|Rhodospirillales	G	COG3959 Transketolase, N-terminal subunit	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
CH3_k127_6026449_5	1121033.AUCF01000009_gene1173	1.077e-121	397.0	COG3958@1|root,COG3958@2|Bacteria,1N6QF@1224|Proteobacteria,2TTU8@28211|Alphaproteobacteria,2JSWY@204441|Rhodospirillales	204441|Rhodospirillales	G	Transketolase, pyrimidine binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
CH3_k127_6026449_9	1121440.AUMA01000005_gene2574	2.61e-81	291.0	COG0546@1|root,COG3173@1|root,COG0546@2|Bacteria,COG3173@2|Bacteria,1R5MY@1224|Proteobacteria,435UQ@68525|delta/epsilon subdivisions,2X9D0@28221|Deltaproteobacteria,2MBGQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
CH3_k127_6026449_12	756272.Plabr_2390	1.867e-51	194.0	COG0705@1|root,COG0705@2|Bacteria,2IZJ7@203682|Planctomycetes	203682|Planctomycetes	S	Rhomboid family	-	-	-	ko:K02441	-	-	-	-	ko00000	-	-	-	Rhomboid,Rhomboid_N
CH3_k127_6026449_8	497964.CfE428DRAFT_3169	2.359e-91	317.0	COG1519@1|root,COG1519@2|Bacteria,46SK9@74201|Verrucomicrobia	74201|Verrucomicrobia	M	PFAM Three-deoxy-D-manno-octulosonic-acid transferase domain protein	kdtA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_1,Glycos_transf_N
CH3_k127_6026449_4	497964.CfE428DRAFT_0922	3.033e-129	422.0	COG2805@1|root,COG2805@2|Bacteria,46SJF@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	PFAM type II secretion system protein E	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
CH3_k127_6026449_15	96561.Dole_1196	8.583e-06	56.0	COG4380@1|root,COG4380@2|Bacteria	2|Bacteria	D	Lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	CsgG,DUF799,Gly-zipper_Omp,NosD,SPOR,TPR_16,TPR_2
CH3_k127_6026449_6	1156937.MFUM_1020111	2.205e-118	396.0	COG1236@1|root,COG1236@2|Bacteria,46SQ0@74201|Verrucomicrobia,37FVJ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	J	Beta-Casp domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta-Casp,Lactamase_B,RMMBL
CH3_k127_6026449_1	1121428.DESHY_110314___1	3.79e-154	528.0	COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,2487T@186801|Clostridia,260SC@186807|Peptococcaceae	186801|Clostridia	L	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Exonuc_V_gamma,PDDEXK_1,UvrD_C
CH3_k127_6026449_0	292459.STH2173	3.65e-163	559.0	COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,248ZF@186801|Clostridia	186801|Clostridia	L	ATP-dependent helicase nuclease subunit A	addA	-	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
CH3_k127_6026449_17	1121468.AUBR01000018_gene2682	0.0001166	53.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,24MQK@186801|Clostridia,42GBG@68295|Thermoanaerobacterales	186801|Clostridia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
CH3_k127_6026449_16	243231.GSU1899	1.259e-05	57.0	COG1463@1|root,COG1463@2|Bacteria,1MY8D@1224|Proteobacteria,42TCA@68525|delta/epsilon subdivisions,2WP6I@28221|Deltaproteobacteria,43UDZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
CH3_k127_6026449_14	401526.TcarDRAFT_1486	4.406e-23	111.0	COG1127@1|root,COG1127@2|Bacteria,1UGV0@1239|Firmicutes,4H251@909932|Negativicutes	909932|Negativicutes	Q	ABC transporter, ATP-binding protein	ttg2A	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
CH3_k127_6026449_13	398767.Glov_1965	3.713e-23	109.0	COG0767@1|root,COG0767@2|Bacteria,1NSBS@1224|Proteobacteria,42ZGY@68525|delta/epsilon subdivisions	1224|Proteobacteria	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
CH3_k127_6026449_11	497964.CfE428DRAFT_2511	1.1e-67	235.0	COG0417@1|root,COG0417@2|Bacteria,46SS2@74201|Verrucomicrobia	74201|Verrucomicrobia	L	RNase_H superfamily	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	RNase_H_2
CH3_k127_6070235_0	1307759.JOMJ01000004_gene2829	5.174e-135	442.0	COG3039@1|root,COG3039@2|Bacteria,1MVTU@1224|Proteobacteria,42Q03@68525|delta/epsilon subdivisions,2WMFQ@28221|Deltaproteobacteria,2MBAU@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	Transposase domain (DUF772)	-	-	-	ko:K07481	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
CH3_k127_6070235_6	1448139.AI20_18275	4.2e-05	52.0	COG2207@1|root,COG2207@2|Bacteria,1QTTB@1224|Proteobacteria,1T1GI@1236|Gammaproteobacteria,1Y5WC@135624|Aeromonadales	135624|Aeromonadales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
CH3_k127_6070235_4	883080.HMPREF9697_03953	4e-25	111.0	COG1487@1|root,COG1487@2|Bacteria,1RIB5@1224|Proteobacteria,2VGZ3@28211|Alphaproteobacteria,3JZA4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	vapC	-	-	ko:K07062	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PIN
CH3_k127_6070235_5	562970.Btus_3182	8.382e-11	65.0	COG2161@1|root,COG2161@2|Bacteria	2|Bacteria	D	toxin-antitoxin pair type II binding	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
CH3_k127_6070235_9	1469607.KK073768_gene4628	0.0004793	45.0	2EHRH@1|root,33BH9@2|Bacteria,1GA8J@1117|Cyanobacteria	1117|Cyanobacteria	S	Domain of unknown function (DUF4926)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4926
CH3_k127_6070235_8	1492922.GY26_17225	0.0003676	45.0	COG2944@1|root,COG2944@2|Bacteria,1NH2C@1224|Proteobacteria,1TBCJ@1236|Gammaproteobacteria,1JBN2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MqsA_antitoxin
CH3_k127_6070235_1	1396141.BATP01000006_gene5432	3.259e-114	395.0	COG2312@1|root,COG2885@1|root,COG3209@1|root,COG3210@1|root,COG2312@2|Bacteria,COG2885@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,46XSC@74201|Verrucomicrobia,2IWGQ@203494|Verrucomicrobiae	2|Bacteria	M	CotH kinase protein	-	-	-	ko:K02487,ko:K12543	ko02020,map02020	M00330,M00507	-	-	ko00000,ko00001,ko00002,ko02000,ko02022,ko02035,ko02044	1.B.17,3.A.1.109.4	-	-	CotH,Erythro_esteras,LTD,OmpA
CH3_k127_6070235_3	167539.Pro_1266	3.215e-34	140.0	2DMQB@1|root,32SZR@2|Bacteria	2|Bacteria	S	VTC domain	-	-	-	-	-	-	-	-	-	-	-	-	VTC
CH3_k127_6070235_2	167539.Pro_1264	1.998e-39	156.0	COG1285@1|root,COG1285@2|Bacteria	2|Bacteria	E	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
CH3_k127_6070235_7	1101192.KB910516_gene2785	9.106e-05	46.0	COG0265@1|root,COG0265@2|Bacteria,1MV63@1224|Proteobacteria,2TS54@28211|Alphaproteobacteria,1JRCY@119045|Methylobacteriaceae	28211|Alphaproteobacteria	O	Trypsin-like peptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,Trypsin_2
CH3_k127_6070235_10	1396141.BATP01000003_gene4936	0.00055	46.0	COG1404@1|root,COG3266@1|root,COG1404@2|Bacteria,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	pstP	GO:0000287,GO:0001932,GO:0001933,GO:0003674,GO:0003824,GO:0004647,GO:0004721,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006469,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009892,GO:0009987,GO:0010563,GO:0010605,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019220,GO:0019222,GO:0019538,GO:0030145,GO:0030312,GO:0031224,GO:0031226,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0032268,GO:0032269,GO:0033673,GO:0036211,GO:0042325,GO:0042326,GO:0042578,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043392,GO:0043412,GO:0043549,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0045859,GO:0045936,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051098,GO:0051100,GO:0051101,GO:0051171,GO:0051172,GO:0051174,GO:0051246,GO:0051248,GO:0051338,GO:0051348,GO:0060255,GO:0065007,GO:0065009,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	3.1.3.16,3.4.21.62	ko:K01342,ko:K12056,ko:K12287,ko:K20074,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01009,ko02044,ko03110	3.A.7.11.1	-	-	FG-GAP,PP2C_2,PPC,Peptidase_C2,Peptidase_S8,VCBS
CH3_k127_6102028_2	452637.Oter_1638	6.607e-107	351.0	COG1136@1|root,COG1136@2|Bacteria,46SI5@74201|Verrucomicrobia,3K7NZ@414999|Opitutae	414999|Opitutae	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CH3_k127_6102028_1	497964.CfE428DRAFT_6510	1.987e-135	444.0	COG0845@1|root,COG0845@2|Bacteria,46SKN@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
CH3_k127_6102028_0	452637.Oter_0618	8.184e-148	477.0	COG3591@1|root,COG3591@2|Bacteria,46UUQ@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Peptidase S46	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
CH3_k127_6122256_0	1267535.KB906767_gene2309	5.283e-94	317.0	COG0329@1|root,COG0329@2|Bacteria	2|Bacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	kdgD	-	4.2.1.41	ko:K01707	ko00053,ko01100,map00053,map01100	-	R02279	RC00678	ko00000,ko00001,ko01000	-	-	-	DHDPS
CH3_k127_6122256_1	452637.Oter_3025	9.325e-92	314.0	COG0684@1|root,COG0684@2|Bacteria,46VAD@74201|Verrucomicrobia,3K8HM@414999|Opitutae	414999|Opitutae	H	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
CH3_k127_6122256_2	945713.IALB_0846	6.427e-17	93.0	COG1520@1|root,COG1572@1|root,COG3291@1|root,COG4733@1|root,COG1520@2|Bacteria,COG1572@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,Malectin,fn3
CH3_k127_6122256_3	661478.OP10G_2992	3.924e-12	76.0	COG4537@1|root,COG4537@2|Bacteria	2|Bacteria	U	Required for transformation and DNA binding	comGC	GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944	-	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	M00331,M00429	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
CH3_k127_6122256_4	1121930.AQXG01000002_gene2124	2.287e-10	70.0	COG1404@1|root,COG1404@2|Bacteria,4PPN8@976|Bacteroidetes,1J10J@117747|Sphingobacteriia	2|Bacteria	O	SusE outer membrane protein	-	-	-	ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	DUF1573,LTD,Laminin_G_3,SusE
CH3_k127_6122700_3	96561.Dole_1704	1.999e-22	114.0	COG3420@1|root,COG3420@2|Bacteria,1MZHI@1224|Proteobacteria,43BRC@68525|delta/epsilon subdivisions,2WUM4@28221|Deltaproteobacteria,2MN6K@213118|Desulfobacterales	1224|Proteobacteria	P	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_6122700_2	518766.Rmar_0474	9.18e-106	354.0	COG2017@1|root,COG2017@2|Bacteria,4NF5G@976|Bacteroidetes	976|Bacteroidetes	G	Converts alpha-aldose to the beta-anomer	galM	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
CH3_k127_6122700_0	583355.Caka_0968	3.707e-140	467.0	COG1858@1|root,COG3391@1|root,COG1858@2|Bacteria,COG3391@2|Bacteria,46UC1@74201|Verrucomicrobia,3K9FB@414999|Opitutae	414999|Opitutae	C	TIGRFAM 40-residue YVTN family beta-propeller repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_6122700_4	1353531.AZNX01000005_gene3441	1.097e-21	99.0	COG2017@1|root,COG2017@2|Bacteria,1MVMN@1224|Proteobacteria,2TTJ7@28211|Alphaproteobacteria,4BC0Q@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	Aldose 1-epimerase	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
CH3_k127_6122700_1	404589.Anae109_3197	1.236e-135	436.0	COG2855@1|root,COG2855@2|Bacteria,1MVPE@1224|Proteobacteria,42NT6@68525|delta/epsilon subdivisions,2WJ9R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	family UPF0324	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth698
CH3_k127_6144032_2	452637.Oter_0314	5.052e-43	169.0	COG5373@1|root,COG5373@2|Bacteria,46UM1@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF3999)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3999
CH3_k127_6144032_1	661478.OP10G_3858	9.301e-127	416.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	yrbE	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CH3_k127_6144032_0	595460.RRSWK_04532	4.752e-188	594.0	COG0673@1|root,COG0673@2|Bacteria,2IXPT@203682|Planctomycetes	203682|Planctomycetes	S	PFAM oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CH3_k127_6178440_26	1150469.RSPPHO_02781	0.0005539	47.0	COG2165@1|root,COG2165@2|Bacteria,1PJ5F@1224|Proteobacteria,2VC7I@28211|Alphaproteobacteria,2JY2W@204441|Rhodospirillales	204441|Rhodospirillales	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_6178440_5	861299.J421_5609	2.297e-115	380.0	COG1879@1|root,COG1879@2|Bacteria,1ZV3Z@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Periplasmic binding proteins and sugar binding domain of LacI family	-	-	-	ko:K10439,ko:K10552	ko02010,ko02030,map02010,map02030	M00212,M00218	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.7	-	-	Peripla_BP_4
CH3_k127_6178440_7	861299.J421_5600	7.007e-94	319.0	COG1172@1|root,COG1172@2|Bacteria,1ZUX9@142182|Gemmatimonadetes	142182|Gemmatimonadetes	U	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10440,ko:K10553	ko02010,map02010	M00212,M00218	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.7	-	-	BPD_transp_2
CH3_k127_6178440_10	435832.HMPREF0604_01422	1.103e-67	239.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2VM3A@28216|Betaproteobacteria,2KPMA@206351|Neisseriales	206351|Neisseriales	KLT	Psort location Extracellular, score	-	-	-	-	-	-	-	-	-	-	-	-	Sel1
CH3_k127_6178440_11	497964.CfE428DRAFT_3997	1.902e-62	227.0	COG0515@1|root,COG0515@2|Bacteria,46TX9@74201|Verrucomicrobia	74201|Verrucomicrobia	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,RicinB_lectin_2
CH3_k127_6178440_17	497964.CfE428DRAFT_4502	6.107e-27	114.0	COG0607@1|root,COG0607@2|Bacteria,46W9V@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CH3_k127_6178440_18	497964.CfE428DRAFT_3831	1.861e-16	88.0	2EM72@1|root,33EW9@2|Bacteria,46TAB@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Lipopolysaccharide-assembly	-	-	-	-	-	-	-	-	-	-	-	-	LptE
CH3_k127_6178440_12	1156937.MFUM_270037	4.083e-51	194.0	COG1729@1|root,COG4105@1|root,COG1729@2|Bacteria,COG4105@2|Bacteria,46SYU@74201|Verrucomicrobia,37GE7@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Outer membrane lipoprotein	-	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	TPR_16,TPR_6,YfiO
CH3_k127_6178440_27	497964.CfE428DRAFT_0660	0.0007884	49.0	COG1196@1|root,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	DUF1542,DUF349,DUF4446,FIVAR,GA,Gram_pos_anchor,PhageMin_Tail
CH3_k127_6178440_4	497964.CfE428DRAFT_1395	2.938e-131	446.0	COG1262@1|root,COG1262@2|Bacteria,46UX3@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PSCyt1
CH3_k127_6178440_8	521674.Plim_0037	1.817e-92	320.0	COG0673@1|root,COG0673@2|Bacteria,2IXFW@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CH3_k127_6178440_6	886293.Sinac_4427	7.129e-108	360.0	COG3023@1|root,COG3023@2|Bacteria,2J257@203682|Planctomycetes	203682|Planctomycetes	V	N-acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2
CH3_k127_6178440_2	886293.Sinac_6958	7.285e-248	771.0	COG1524@1|root,COG1524@2|Bacteria,2J563@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CH3_k127_6178440_22	504487.JCM19302_1724	1.174e-07	59.0	2CCSR@1|root,32RWC@2|Bacteria,4NSDM@976|Bacteroidetes,1I40W@117743|Flavobacteriia	976|Bacteroidetes	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
CH3_k127_6178440_0	240016.ABIZ01000001_gene3033	0.0	1128.0	COG2010@1|root,COG2010@2|Bacteria,46TQ0@74201|Verrucomicrobia,2ITRS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Protein of unknown function (DUF1553)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
CH3_k127_6178440_19	661478.OP10G_4802	4.2e-12	76.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02650,ko:K02679	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10
CH3_k127_6178440_3	1396418.BATQ01000014_gene4352	1.511e-152	490.0	COG3616@1|root,COG3616@2|Bacteria,46TAP@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Putative serine dehydratase domain	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N,D-ser_dehydrat
CH3_k127_6178440_20	522373.Smlt0682	3.008e-11	74.0	COG3325@1|root,COG3325@2|Bacteria,1MWAR@1224|Proteobacteria,1RPNS@1236|Gammaproteobacteria,1X5BZ@135614|Xanthomonadales	135614|Xanthomonadales	G	chitinase	-	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	Calx-beta,Glyco_hydro_18,fn3
CH3_k127_6178440_16	316274.Haur_2251	4.158e-31	144.0	COG1629@1|root,COG3055@1|root,COG1629@2|Bacteria,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Kelch_1,Plug
CH3_k127_6178440_1	452637.Oter_0135	1.483e-305	951.0	COG0480@1|root,COG0480@2|Bacteria,46SFV@74201|Verrucomicrobia,3K7PT@414999|Opitutae	74201|Verrucomicrobia	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
CH3_k127_6178440_23	1125700.HMPREF9195_01844	2.118e-06	58.0	2AIAW@1|root,318RT@2|Bacteria,2J6NU@203691|Spirochaetes	203691|Spirochaetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_6178440_21	742159.HMPREF0004_3321	5.768e-09	64.0	COG0745@1|root,COG2199@1|root,COG5002@1|root,COG5278@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,COG5002@2|Bacteria,COG5278@2|Bacteria,1R7HC@1224|Proteobacteria,2W0FN@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HATPase_c,HisKA,Response_reg
CH3_k127_6178440_14	497964.CfE428DRAFT_3383	3.523e-40	156.0	COG0262@1|root,COG0262@2|Bacteria,46T19@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Dihydrofolate reductase	-	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	DHFR_1
CH3_k127_6178440_9	1379698.RBG1_1C00001G0607	5.462e-92	340.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
CH3_k127_6178440_13	1082933.MEA186_06096	3.075e-44	186.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_8
CH3_k127_6178440_15	243090.RB9985	5.352e-38	149.0	28JE3@1|root,2Z98B@2|Bacteria,2J0PD@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_6178440_25	1047013.AQSP01000089_gene1181	1.286e-05	48.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	cyaJ	-	4.6.1.1	ko:K01768,ko:K02483	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	Guanylate_cyc,HTH_18,TPR_16,TPR_19,TPR_2,TPR_8
CH3_k127_6183779_8	547042.BACCOPRO_02053	7.736e-08	54.0	COG0338@1|root,COG0338@2|Bacteria,4NRXP@976|Bacteroidetes,2G0SN@200643|Bacteroidia,4AVDJ@815|Bacteroidaceae	976|Bacteroidetes	L	DNA N-6-adenine-methyltransferase (Dam)	-	-	-	-	-	-	-	-	-	-	-	-	Dam
CH3_k127_6183779_7	1120919.AUBI01000025_gene3569	3.564e-28	119.0	COG1343@1|root,COG1343@2|Bacteria,1MZ9Q@1224|Proteobacteria,2UCZV@28211|Alphaproteobacteria,2JTHY@204441|Rhodospirillales	204441|Rhodospirillales	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas2	-	-	ko:K09951	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_Cas2
CH3_k127_6183779_2	649638.Trad_1672	7.545e-95	323.0	COG1518@1|root,COG1518@2|Bacteria,1WIUQ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	-	-	-	ko:K15342	-	-	-	-	ko00000,ko02048,ko03400	-	-	-	Cas_Cas1
CH3_k127_6183779_5	1121413.JMKT01000001_gene1686	4.501e-50	184.0	COG0399@1|root,COG0399@2|Bacteria,1N0QW@1224|Proteobacteria,42W70@68525|delta/epsilon subdivisions,2X245@28221|Deltaproteobacteria,2MFSC@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
CH3_k127_6183779_6	335283.Neut_1014	2.353e-45	175.0	COG1468@1|root,COG1468@2|Bacteria,1MX2S@1224|Proteobacteria,2VR7Q@28216|Betaproteobacteria,374FT@32003|Nitrosomonadales	28216|Betaproteobacteria	L	TIGRFAM CRISPR-associated protein Cas4	cas4	-	3.1.12.1	ko:K07464	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Cas_Cas4
CH3_k127_6183779_1	1227272.HMPREF1556_02010	4.691e-100	334.0	COG3649@1|root,COG3649@2|Bacteria,4NNSG@976|Bacteroidetes	976|Bacteroidetes	L	Psort location Cytoplasmic, score	-	-	-	ko:K19115,ko:K19118	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Cas7
CH3_k127_6183779_3	1249627.D779_1646	1.075e-83	300.0	28HN3@1|root,2Z7WH@2|Bacteria,1MWH8@1224|Proteobacteria,1RYMP@1236|Gammaproteobacteria,1WXH2@135613|Chromatiales	135613|Chromatiales	S	TIGRFAM CRISPR-associated protein	-	-	-	ko:K19117	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Csd1
CH3_k127_6183779_4	1192034.CAP_3265	1.329e-53	197.0	2DBAF@1|root,2Z82V@2|Bacteria,1MWRM@1224|Proteobacteria,42QYM@68525|delta/epsilon subdivisions,2WMS8@28221|Deltaproteobacteria,2YXEQ@29|Myxococcales	28221|Deltaproteobacteria	S	CRISPR-associated protein (Cas_Cas5)	-	-	-	ko:K19119	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Cas5d
CH3_k127_6183779_0	644968.DFW101_1322	1.869e-140	471.0	COG1203@1|root,COG1203@2|Bacteria,1MX7A@1224|Proteobacteria,42Q2Q@68525|delta/epsilon subdivisions,2WJEP@28221|Deltaproteobacteria,2M900@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	TIGRFAM CRISPR-associated	-	-	-	ko:K07012	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DEAD,HD,Helicase_C,ResIII
CH3_k127_6190161_5	497964.CfE428DRAFT_0111	6.757e-13	80.0	2CMJG@1|root,32SEZ@2|Bacteria,46T0G@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_6190161_1	1046724.KB889951_gene1982	2.938e-123	406.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,1RPI8@1236|Gammaproteobacteria,464UI@72275|Alteromonadaceae	1236|Gammaproteobacteria	D	COG4974 Site-specific recombinase XerD	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
CH3_k127_6190161_3	1046724.KB889951_gene1983	1.096e-74	265.0	COG0582@1|root,COG0582@2|Bacteria,1NX90@1224|Proteobacteria	1224|Proteobacteria	L	Integrase	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
CH3_k127_6190161_2	1046724.KB889951_gene1984	5.595e-95	325.0	COG4974@1|root,COG4974@2|Bacteria,1QUHS@1224|Proteobacteria,1S2C4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Integrase	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
CH3_k127_6190161_0	237368.SCABRO_00954	8.047e-192	612.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_4
CH3_k127_6190161_4	1379698.RBG1_1C00001G1509	2.804e-59	228.0	COG1520@1|root,COG1520@2|Bacteria,2NQ51@2323|unclassified Bacteria	2|Bacteria	O	NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,SBBP
CH3_k127_6191905_15	452471.Aasi_1218	2.911e-07	56.0	COG0790@1|root,COG1196@1|root,COG0790@2|Bacteria,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
CH3_k127_6191905_5	382464.ABSI01000006_gene864	2.874e-162	518.0	COG1225@1|root,COG1225@2|Bacteria,46TJA@74201|Verrucomicrobia,2ITIP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CH3_k127_6191905_14	1121468.AUBR01000005_gene35	1.65e-10	74.0	COG1716@1|root,COG1716@2|Bacteria,1V5U0@1239|Firmicutes,24IDE@186801|Clostridia,42H0N@68295|Thermoanaerobacterales	186801|Clostridia	T	Protein of unknown function (DUF2662)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3662,Yop-YscD_cpl
CH3_k127_6191905_2	886293.Sinac_2090	4.358e-200	631.0	COG0823@1|root,COG0823@2|Bacteria,2IZ00@203682|Planctomycetes	203682|Planctomycetes	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	-
CH3_k127_6191905_1	452637.Oter_3674	1.66e-289	899.0	COG0008@1|root,COG0008@2|Bacteria,46S4X@74201|Verrucomicrobia,3K7DH@414999|Opitutae	414999|Opitutae	J	glutaminyl-tRNA synthetase	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
CH3_k127_6191905_13	414684.RC1_3800	6.299e-27	121.0	2DB9X@1|root,2Z7ZS@2|Bacteria,1N6CK@1224|Proteobacteria,2U2ME@28211|Alphaproteobacteria,2JWW7@204441|Rhodospirillales	204441|Rhodospirillales	S	Protein of unknown function (DUF3445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3445
CH3_k127_6191905_11	469383.Cwoe_0748	1.351e-50	186.0	COG0288@1|root,COG0288@2|Bacteria,2GNJF@201174|Actinobacteria	201174|Actinobacteria	P	Reversible hydration of carbon dioxide	cynT	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
CH3_k127_6191905_10	517418.Ctha_1742	9.432e-53	194.0	COG0041@1|root,COG0041@2|Bacteria,1FDYI@1090|Chlorobi	1090|Chlorobi	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
CH3_k127_6191905_6	319003.Bra1253DRAFT_02062	3.262e-81	276.0	COG3848@1|root,COG3848@2|Bacteria,1R7DS@1224|Proteobacteria,2U3SK@28211|Alphaproteobacteria,3JSC8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Pyruvate phosphate dikinase	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_6191905_12	497964.CfE428DRAFT_2007	3.637e-33	137.0	COG0558@1|root,COG0558@2|Bacteria,46T66@74201|Verrucomicrobia	74201|Verrucomicrobia	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
CH3_k127_6191905_9	194439.CT0662	8.545e-60	210.0	COG1225@1|root,COG1225@2|Bacteria,1FDZX@1090|Chlorobi	1090|Chlorobi	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
CH3_k127_6191905_7	497964.CfE428DRAFT_0793	1.189e-74	253.0	COG0450@1|root,COG0450@2|Bacteria,46STI@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
CH3_k127_6191905_3	1123276.KB893270_gene4720	3.628e-199	632.0	COG0673@1|root,COG0673@2|Bacteria,4NHDZ@976|Bacteroidetes,47KJR@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CH3_k127_6191905_4	1267534.KB906758_gene2376	7.113e-198	626.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CH3_k127_6191905_0	497964.CfE428DRAFT_1607	7.355e-319	990.0	COG1048@1|root,COG1048@2|Bacteria,46SFS@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
CH3_k127_6194496_0	1174528.JH992898_gene4971	1.363e-230	727.0	COG0826@1|root,COG0826@2|Bacteria,1G3NG@1117|Cyanobacteria,1JGWD@1189|Stigonemataceae	1117|Cyanobacteria	O	Collagenase	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32,Peptidase_U32_C
CH3_k127_6194496_6	357808.RoseRS_2451	1.807e-05	58.0	COG4870@1|root,COG4932@1|root,COG5513@1|root,COG4870@2|Bacteria,COG4932@2|Bacteria,COG5513@2|Bacteria,2GA24@200795|Chloroflexi,377PH@32061|Chloroflexia	2|Bacteria	MO	Carboxypeptidase regulatory-like domain	-	-	3.4.22.15	ko:K01365,ko:K02030,ko:K14475	ko04140,ko04142,ko04145,ko04210,ko04612,ko05143,ko05205,ko05323,ko05418,map04140,map04142,map04145,map04210,map04612,map05143,map05205,map05323,map05418	M00236	-	-	ko00000,ko00001,ko00002,ko00537,ko01000,ko01002,ko02000,ko03110	3.A.1.3	-	-	CarboxypepD_reg,Inhibitor_I42,Peptidase_C1
CH3_k127_6194496_1	316067.Geob_0443	1.736e-76	268.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,42NJJ@68525|delta/epsilon subdivisions,2WJGI@28221|Deltaproteobacteria,43SZG@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)	pdxA	-	1.1.1.262,1.1.1.408,1.1.1.409	ko:K00097,ko:K22024	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
CH3_k127_6194496_2	481448.Minf_0292	2.058e-59	217.0	COG0760@1|root,COG0760@2|Bacteria,46SU4@74201|Verrucomicrobia,37G1D@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
CH3_k127_6194496_4	1395587.P364_0100735	1.68e-31	136.0	COG1409@1|root,COG1409@2|Bacteria,1V574@1239|Firmicutes,4HW52@91061|Bacilli,26S57@186822|Paenibacillaceae	91061|Bacilli	S	metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
CH3_k127_6194496_5	926551.KB900703_gene1072	9.18e-18	95.0	COG4124@1|root,COG4124@2|Bacteria,4NEZG@976|Bacteroidetes,1HYFM@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 26 family	-	-	3.2.1.78	ko:K01218	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000	-	GH26	-	Glyco_hydro_26
CH3_k127_6194496_3	1396418.BATQ01000083_gene1173	3.321e-58	214.0	COG0438@1|root,COG0438@2|Bacteria,46ZHN@74201|Verrucomicrobia,2IUVI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CH3_k127_6199357_5	497964.CfE428DRAFT_1500	1e-09	63.0	COG2165@1|root,COG2165@2|Bacteria,46T8M@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
CH3_k127_6199357_4	497964.CfE428DRAFT_6230	5.012e-24	106.0	COG0784@1|root,COG2204@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2204@2|Bacteria,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	ko:K01991,ko:K03413	ko02020,ko02026,ko02030,map02020,map02026,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02000,ko02022,ko02035	1.B.18	-	-	GAF_2,HATPase_c,HisKA,PAS_9,Response_reg
CH3_k127_6199357_2	1123278.KB893545_gene4805	9.004e-81	293.0	COG1397@1|root,COG1397@2|Bacteria,4NG36@976|Bacteroidetes,47K8Y@768503|Cytophagia	976|Bacteroidetes	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
CH3_k127_6199357_1	429009.Adeg_0221	4.288e-117	383.0	COG0115@1|root,COG0115@2|Bacteria,1TPY2@1239|Firmicutes,25CC3@186801|Clostridia,42F8X@68295|Thermoanaerobacterales	186801|Clostridia	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
CH3_k127_6199357_3	497964.CfE428DRAFT_3441	9.509e-52	189.0	COG3880@1|root,COG3880@2|Bacteria,46SXX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM UvrB UvrC protein	mcsA	-	-	ko:K19411	-	-	-	-	ko00000	-	-	-	UVR
CH3_k127_6199357_0	497964.CfE428DRAFT_3440	6.937e-123	405.0	COG3869@1|root,COG3869@2|Bacteria,46S55@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Protein-arginine kinase	mcsB	-	2.7.14.1	ko:K19405	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	ATP-gua_Ptrans
CH3_k127_6228129_4	1121920.AUAU01000009_gene1881	5.254e-36	159.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,I-set,Ig_3,PKD,Peptidase_S8
CH3_k127_6228129_3	1396141.BATP01000042_gene1928	3.052e-39	171.0	COG5337@1|root,COG5337@2|Bacteria	2|Bacteria	M	Spore coat protein CotH	cotH	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
CH3_k127_6228129_0	1396141.BATP01000043_gene1929	6.604e-248	837.0	COG5337@1|root,COG5337@2|Bacteria,46ZJW@74201|Verrucomicrobia,2IVD0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
CH3_k127_6228129_2	1283300.ATXB01000001_gene1507	5.569e-41	158.0	COG4636@1|root,COG4636@2|Bacteria,1R58B@1224|Proteobacteria,1S53A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
CH3_k127_6228129_1	497964.CfE428DRAFT_5616	1.401e-124	416.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	DLH,DUF1929,Glyoxal_oxid_N
CH3_k127_6249730_0	497964.CfE428DRAFT_1032	8.576e-263	834.0	COG3170@1|root,COG3170@2|Bacteria,46W02@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_6249730_1	314230.DSM3645_10617	4.978e-97	345.0	COG3420@1|root,COG3420@2|Bacteria,2J2DV@203682|Planctomycetes	203682|Planctomycetes	P	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
CH3_k127_6250741_3	382464.ABSI01000010_gene3213	3.716e-153	496.0	COG0673@1|root,COG0673@2|Bacteria,46UYM@74201|Verrucomicrobia,2IVG2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CH3_k127_6250741_0	497964.CfE428DRAFT_3010	0.0	1396.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,46TRH@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Tricorn protease PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
CH3_k127_6250741_2	497964.CfE428DRAFT_5350	8.478e-159	518.0	COG5267@1|root,COG5267@2|Bacteria,46SWV@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
CH3_k127_6250741_4	1403819.BATR01000042_gene1250	2.842e-99	337.0	COG4102@1|root,COG4102@2|Bacteria,46T50@74201|Verrucomicrobia,2IUKB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CH3_k127_6250741_5	1366050.N234_08390	2.74e-28	121.0	COG0527@1|root,COG0527@2|Bacteria,1REUY@1224|Proteobacteria,2VS69@28216|Betaproteobacteria,1K7HV@119060|Burkholderiaceae	2|Bacteria	E	ACT domain	-	-	1.1.1.3,2.7.2.4	ko:K00003,ko:K00928,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_6,Homoserine_dh,NAD_binding_3
CH3_k127_6250741_1	497964.CfE428DRAFT_0788	2.925e-164	520.0	COG0362@1|root,COG0362@2|Bacteria,46SDE@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
CH3_k127_6282227_5	452637.Oter_4248	7.296e-17	86.0	COG5184@1|root,COG5184@2|Bacteria,46Z7H@74201|Verrucomicrobia,3K9VS@414999|Opitutae	2|Bacteria	DZ	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new,RCC1,RCC1_2
CH3_k127_6282227_0	1293054.HSACCH_00337	2.246e-128	417.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,3WAI0@53433|Halanaerobiales	186801|Clostridia	P	TIGRFAM oligopeptide dipeptide ABC transporter, ATP-binding protein, C-terminal domain	appF	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
CH3_k127_6282227_6	1996.JOFO01000032_gene1329	9.773e-09	62.0	2ER32@1|root,33INP@2|Bacteria,2IPCY@201174|Actinobacteria,4EPID@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4259
CH3_k127_6282227_2	926550.CLDAP_11070	4.208e-103	345.0	COG0444@1|root,COG0444@2|Bacteria,2G5PT@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
CH3_k127_6282227_1	497964.CfE428DRAFT_4021	1.576e-104	357.0	COG1600@1|root,COG1600@2|Bacteria,46SDV@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Domain of unknown function (DUF1730)	-	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
CH3_k127_6282227_4	452637.Oter_4020	1.546e-34	138.0	COG0703@1|root,COG0703@2|Bacteria,46YZV@74201|Verrucomicrobia,3K80S@414999|Opitutae	414999|Opitutae	H	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
CH3_k127_6282227_7	5341.XP_007326237.1	6.841e-08	62.0	2CYVH@1|root,2S6PS@2759|Eukaryota,39RW6@33154|Opisthokonta,3NZFC@4751|Fungi,3V2QR@5204|Basidiomycota,227D7@155619|Agaricomycetes,3W5S1@5338|Agaricales	4751|Fungi	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25
CH3_k127_6282227_3	497964.CfE428DRAFT_0084	6.157e-62	230.0	COG0859@1|root,COG0859@2|Bacteria	2|Bacteria	M	ADP-heptose-lipopolysaccharide heptosyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
CH3_k127_6282506_0	1077285.AGDG01000045_gene2975	7.259e-263	844.0	COG0383@1|root,COG0383@2|Bacteria,4NI6N@976|Bacteroidetes,2FQGF@200643|Bacteroidia,4ANYA@815|Bacteroidaceae	976|Bacteroidetes	G	COG COG0383 Alpha-mannosidase	-	-	-	-	-	-	-	-	-	-	-	-	CBM-like,Glyco_hydro_38,Glyco_hydro_38C
CH3_k127_6282506_9	1121378.KB899733_gene4289	5.091e-13	83.0	COG1874@1|root,COG1874@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	3.2.1.97	ko:K17624	-	-	-	-	ko00000,ko01000	-	GH101	-	ASH,Beta_helix,F5_F8_type_C,Glyco_hyd_101C,Glyco_hydro_101,Glyco_hydro_42,He_PIG,NPCBM,NPCBM_assoc,Pectate_lyase_3,VCBS
CH3_k127_6282506_4	1211813.CAPH01000001_gene1170	9.185e-126	434.0	COG3345@1|root,COG3345@2|Bacteria,4NZUR@976|Bacteroidetes,2FNUD@200643|Bacteroidia	976|Bacteroidetes	G	Melibiase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Melibiase
CH3_k127_6282506_6	314230.DSM3645_20877	2.36e-85	292.0	COG1506@1|root,COG2755@1|root,COG1506@2|Bacteria,COG2755@2|Bacteria,2J4YR@203682|Planctomycetes	203682|Planctomycetes	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CH3_k127_6282506_3	313628.LNTAR_20082	5.884e-133	436.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	yteT	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CH3_k127_6282506_7	180332.JTGN01000003_gene1990	8.024e-80	278.0	COG0407@1|root,COG0407@2|Bacteria,1TW8J@1239|Firmicutes,24BSH@186801|Clostridia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
CH3_k127_6282506_2	1499967.BAYZ01000152_gene1425	4.689e-170	556.0	COG3534@1|root,COG3534@2|Bacteria	2|Bacteria	G	alpha-L-arabinofuranosidase	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
CH3_k127_6282506_5	1492737.FEM08_16340	1.758e-123	449.0	COG3345@1|root,COG3345@2|Bacteria	2|Bacteria	G	alpha-galactosidase	rafA	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_36C,Glyco_hydro_36N,Melibiase
CH3_k127_6282506_1	682795.AciX8_2691	6.862e-250	843.0	COG1554@1|root,COG1554@2|Bacteria,3Y42V@57723|Acidobacteria,2JKPE@204432|Acidobacteriia	204432|Acidobacteriia	G	Glycosyl hydrolase family 65, N-terminal domain	-	-	3.2.1.51	ko:K15923	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	GH95	-	Glyco_hyd_65N_2
CH3_k127_6282506_8	1122194.AUHU01000009_gene3274	4.711e-36	153.0	COG3387@1|root,COG3387@2|Bacteria,1MW9J@1224|Proteobacteria,1T2G2@1236|Gammaproteobacteria,465X7@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	PFAM Glycoside hydrolase 15-related	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,GDE_C
CH3_k127_6296306_9	720554.Clocl_0784	4.36e-48	182.0	COG0145@1|root,COG0145@2|Bacteria,1V3GN@1239|Firmicutes,25DNJ@186801|Clostridia,3WPEF@541000|Ruminococcaceae	186801|Clostridia	EQ	Protein of unknown function (DUF1638)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1638
CH3_k127_6296306_3	497964.CfE428DRAFT_1943	7.983e-127	413.0	COG2133@1|root,COG2133@2|Bacteria,46THQ@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CH3_k127_6296306_4	240016.ABIZ01000001_gene4842	7.599e-112	373.0	COG2115@1|root,COG2115@2|Bacteria	2|Bacteria	G	xylose isomerase activity	-	-	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
CH3_k127_6296306_1	697281.Mahau_1189	3.005e-219	712.0	COG3408@1|root,COG3408@2|Bacteria,1TPY5@1239|Firmicutes,249U8@186801|Clostridia,42EMX@68295|Thermoanaerobacterales	186801|Clostridia	G	alpha-L-rhamnosidase domain protein	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
CH3_k127_6296306_7	497964.CfE428DRAFT_6227	1.577e-67	240.0	COG0676@1|root,COG0676@2|Bacteria,46VKE@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Aldose 1-epimerase	-	-	5.1.3.15	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	-	R02739	RC00563	ko00000,ko00001,ko01000	-	-	-	Aldose_epim
CH3_k127_6296306_8	452637.Oter_4232	2.237e-53	192.0	2F7MR@1|root,34028@2|Bacteria,46VN7@74201|Verrucomicrobia,3K85B@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_6296306_0	452637.Oter_2033	1.242e-256	798.0	COG2268@1|root,COG2268@2|Bacteria,46TRR@74201|Verrucomicrobia,3K887@414999|Opitutae	414999|Opitutae	S	prohibitin homologues	-	-	-	ko:K07192	ko04910,map04910	-	-	-	ko00000,ko00001,ko03036,ko04131,ko04147	-	-	-	Band_7
CH3_k127_6296306_14	485913.Krac_2627	1.487e-08	59.0	28XV3@1|root,2ZJRF@2|Bacteria	2|Bacteria	S	Phospholipase_D-nuclease N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_N
CH3_k127_6296306_11	452637.Oter_2032	3.362e-19	88.0	COG1983@1|root,COG1983@2|Bacteria	2|Bacteria	KT	positive regulation of macromolecule biosynthetic process	-	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	PspC
CH3_k127_6296306_5	452637.Oter_2031	5.797e-82	282.0	COG0288@1|root,COG0288@2|Bacteria	2|Bacteria	P	reversible hydration of carbon dioxide	cah	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
CH3_k127_6296306_10	886293.Sinac_5104	1.685e-42	164.0	COG3468@1|root,COG3468@2|Bacteria,2J1BR@203682|Planctomycetes	203682|Planctomycetes	MU	outer membrane autotransporter barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_6296306_13	588596.U9TEJ9	2.171e-13	76.0	COG0790@1|root,KOG1550@2759|Eukaryota	588596.U9TEJ9|-	T	ERAD pathway	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_6296306_2	497964.CfE428DRAFT_3745	1.735e-169	542.0	COG0761@1|root,COG0761@2|Bacteria,46SAR@74201|Verrucomicrobia	74201|Verrucomicrobia	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	lytB	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
CH3_k127_6296306_15	1396418.BATQ01000091_gene5763	3.487e-05	47.0	COG1989@1|root,COG1989@2|Bacteria,46TWT@74201|Verrucomicrobia,2IU6Y@203494|Verrucomicrobiae	203494|Verrucomicrobiae	NOU	Type IV leader peptidase family	-	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
CH3_k127_6319207_8	1288298.rosmuc_00470	9.236e-35	142.0	COG4238@1|root,COG4238@2|Bacteria,1RDE3@1224|Proteobacteria,2U7FF@28211|Alphaproteobacteria,46P9E@74030|Roseovarius	28211|Alphaproteobacteria	M	major outer membrane lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_6319207_1	1232410.KI421421_gene3328	2.991e-211	666.0	COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,42NG3@68525|delta/epsilon subdivisions,2WJ95@28221|Deltaproteobacteria,43S64@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Domain of unknown function (DUF4070)	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
CH3_k127_6319207_2	1123073.KB899241_gene3250	5.471e-146	472.0	COG3239@1|root,COG3239@2|Bacteria,1MY4I@1224|Proteobacteria,1S0IS@1236|Gammaproteobacteria,1X4IQ@135614|Xanthomonadales	135614|Xanthomonadales	I	Fatty acid desaturase	-	-	1.14.19.23,1.14.19.45	ko:K10255	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
CH3_k127_6319207_0	880072.Desac_1063	2.06e-259	809.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,42PFW@68525|delta/epsilon subdivisions,2WJ1N@28221|Deltaproteobacteria,2MS34@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM Radical SAM superfamily	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
CH3_k127_6319207_6	1403819.BATR01000181_gene6249	2.237e-83	282.0	COG2197@1|root,COG2197@2|Bacteria,46UGC@74201|Verrucomicrobia,2IUI3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CH3_k127_6319207_4	794903.OPIT5_29540	1.687e-106	359.0	COG4585@1|root,COG4585@2|Bacteria,46TVJ@74201|Verrucomicrobia,3K9CA@414999|Opitutae	414999|Opitutae	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
CH3_k127_6319207_17	1267534.KB906754_gene3064	4.853e-06	51.0	2EFZF@1|root,339RM@2|Bacteria,3Y5X5@57723|Acidobacteria,2JK63@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_6319207_13	324925.Ppha_2361	4.34e-16	81.0	2E35S@1|root,32Y5P@2|Bacteria	2|Bacteria	S	Putative prokaryotic signal transducing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2007
CH3_k127_6319207_11	330214.NIDE0935	5.788e-17	89.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	GerE,Response_reg
CH3_k127_6319207_14	443143.GM18_0916	1.145e-15	84.0	COG2133@1|root,COG4447@1|root,COG4733@1|root,COG2133@2|Bacteria,COG4447@2|Bacteria,COG4733@2|Bacteria,1PFCA@1224|Proteobacteria,42WUH@68525|delta/epsilon subdivisions,2WT3I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	fibronectin type III domain protein	-	-	-	-	-	-	-	-	-	-	-	-	fn3
CH3_k127_6319207_16	1123276.KB893245_gene1757	8.07e-10	66.0	29Q3N@1|root,30B2B@2|Bacteria,4NPCV@976|Bacteroidetes,47Q0V@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_6319207_5	794903.OPIT5_27320	7.584e-85	289.0	COG0767@1|root,COG0767@2|Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
CH3_k127_6319207_3	794903.OPIT5_27315	6.393e-117	389.0	COG1463@1|root,COG1463@2|Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, periplasmic component	MA20_08125	-	-	ko:K02067,ko:K06192	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_trans_aux,MlaD
CH3_k127_6319207_15	1167006.UWK_00985	2.21e-14	74.0	2EFZF@1|root,339RM@2|Bacteria,1NH6S@1224|Proteobacteria,42WYZ@68525|delta/epsilon subdivisions,2WT48@28221|Deltaproteobacteria,2MPCB@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_6319207_12	278957.ABEA03000005_gene4416	7.075e-17	81.0	2EK6E@1|root,33DWT@2|Bacteria,46ZJP@74201|Verrucomicrobia,3K8CQ@414999|Opitutae	414999|Opitutae	S	Protein of unknown function (DUF3185)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3185
CH3_k127_6319207_10	765914.ThisiDRAFT_1557	1.249e-17	85.0	2E3KF@1|root,32YIQ@2|Bacteria,1NC3P@1224|Proteobacteria,1SD8X@1236|Gammaproteobacteria,1WZDZ@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_6319207_9	520709.F985_03132	7.778e-26	111.0	2EEQQ@1|root,338IE@2|Bacteria,1N816@1224|Proteobacteria,1SR3D@1236|Gammaproteobacteria,3NS16@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_6319207_7	330214.NIDE3859	2.196e-50	187.0	COG0071@1|root,COG0071@2|Bacteria,3J0TV@40117|Nitrospirae	40117|Nitrospirae	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
CH3_k127_6319207_18	373903.Hore_13580	0.0001222	46.0	COG1032@1|root,COG1032@2|Bacteria,1TPGT@1239|Firmicutes,247JS@186801|Clostridia,3WC51@53433|Halanaerobiales	186801|Clostridia	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4080,Radical_SAM
CH3_k127_6319607_4	1178825.ALIH01000004_gene2807	3.534e-23	103.0	COG3408@1|root,COG5520@1|root,COG3408@2|Bacteria,COG5520@2|Bacteria,4NM34@976|Bacteroidetes	976|Bacteroidetes	M	Glycosyl hydrolase family 59	-	-	3.2.1.46	ko:K01202	ko00600,ko01100,ko04142,map00600,map01100,map04142	-	R03617	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH59	-	Glyco_hydro_59
CH3_k127_6319607_0	1235803.C825_01953	2.974e-273	882.0	COG0639@1|root,COG0639@2|Bacteria,4NZWK@976|Bacteroidetes,2FPXD@200643|Bacteroidia	976|Bacteroidetes	T	alpha-L-rhamnosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106
CH3_k127_6319607_6	1211813.CAPH01000009_gene63	0.0009163	43.0	COG4692@1|root,COG4692@2|Bacteria,4PKSV@976|Bacteroidetes	976|Bacteroidetes	G	Alpha-L-rhamnosidase N-terminal domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	BNR_2,Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
CH3_k127_6319607_3	1396141.BATP01000004_gene5925	1.544e-27	122.0	COG3250@1|root,COG4692@1|root,COG3250@2|Bacteria,COG4692@2|Bacteria,46Z9T@74201|Verrucomicrobia,2IWDF@203494|Verrucomicrobiae	2|Bacteria	G	Alpha-L-rhamnosidase N-terminal domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N,NPCBM_assoc
CH3_k127_6319607_5	335543.Sfum_3211	9.499e-23	111.0	COG3437@1|root,COG4585@1|root,COG3437@2|Bacteria,COG4585@2|Bacteria,1MWPN@1224|Proteobacteria,42RUN@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS,PAS_9
CH3_k127_6319607_2	255470.cbdbA1042	7.358e-45	169.0	COG2202@1|root,COG2203@1|root,COG4585@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4585@2|Bacteria,2G8KS@200795|Chloroflexi,34CTW@301297|Dehalococcoidia	301297|Dehalococcoidia	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3,PAS_3,PAS_9
CH3_k127_6319607_1	452637.Oter_1700	2.738e-66	232.0	COG2197@1|root,COG2197@2|Bacteria,46UGC@74201|Verrucomicrobia,3K7ZK@414999|Opitutae	74201|Verrucomicrobia	K	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CH3_k127_6351345_10	452637.Oter_1501	7.199e-06	51.0	29YN3@1|root,30KHK@2|Bacteria	2|Bacteria	S	Putative ABC exporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_export
CH3_k127_6351345_4	497964.CfE428DRAFT_2506	2.932e-247	769.0	COG0065@1|root,COG0065@2|Bacteria,46SUM@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
CH3_k127_6351345_0	1396141.BATP01000040_gene2167	0.0	1324.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,46TRH@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Tricorn protease PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
CH3_k127_6351345_8	530564.Psta_3458	6.374e-70	251.0	COG1416@1|root,COG4798@1|root,COG1416@2|Bacteria,COG4798@2|Bacteria,2IZ87@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	DrsE,Methyltransf_25
CH3_k127_6351345_7	1287276.X752_02890	9.585e-89	305.0	COG4324@1|root,COG4324@2|Bacteria,1N0FE@1224|Proteobacteria,2UQQC@28211|Alphaproteobacteria,43N9M@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Putative aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Aminopep
CH3_k127_6351345_1	886293.Sinac_7498	3.333e-312	991.0	COG2010@1|root,COG2010@2|Bacteria,2IXZ4@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
CH3_k127_6351345_3	886293.Sinac_7494	4.692e-254	791.0	COG4102@1|root,COG4102@2|Bacteria,2IXKR@203682|Planctomycetes	203682|Planctomycetes	T	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CH3_k127_6351345_9	1235803.C825_05233	2.512e-33	150.0	2CHVP@1|root,2Z866@2|Bacteria,4NJWZ@976|Bacteroidetes,2FY0D@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_6351345_6	639030.JHVA01000001_gene3738	5.836e-89	302.0	COG3836@1|root,COG3836@2|Bacteria,3Y5ZN@57723|Acidobacteria,2JKP5@204432|Acidobacteriia	204432|Acidobacteriia	G	HpcH/HpaI aldolase/citrate lyase family	-	-	4.1.2.52	ko:K02510	ko00350,ko01120,map00350,map01120	-	R01645,R01647	RC00307,RC00572,RC00574,RC03057	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
CH3_k127_6351345_2	234267.Acid_0200	1.237e-281	891.0	COG3661@1|root,COG3661@2|Bacteria,3Y3Q5@57723|Acidobacteria	57723|Acidobacteria	G	Belongs to the glycosyl hydrolase 67 family	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_6351345_5	641524.ADICYQ_2676	7.369e-242	772.0	COG3292@1|root,COG3292@2|Bacteria,4P1XS@976|Bacteroidetes,47U9C@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_6359386_2	670487.Ocepr_1062	1.659e-115	376.0	COG1013@1|root,COG1145@1|root,COG1013@2|Bacteria,COG1145@2|Bacteria,1WN2N@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C
CH3_k127_6359386_9	1123508.JH636456_gene119	8.643e-12	72.0	COG3335@1|root,COG3335@2|Bacteria,2J1BU@203682|Planctomycetes	203682|Planctomycetes	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
CH3_k127_6359386_4	1210884.HG799479_gene15512	1.255e-29	126.0	COG3415@1|root,COG3415@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_23,HTH_29,HTH_32,HTH_33
CH3_k127_6359386_3	670487.Ocepr_1062	1.744e-35	140.0	COG1013@1|root,COG1145@1|root,COG1013@2|Bacteria,COG1145@2|Bacteria,1WN2N@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C
CH3_k127_6359386_5	1396141.BATP01000023_gene577	1.637e-27	122.0	COG0132@1|root,COG0132@2|Bacteria,46VJB@74201|Verrucomicrobia,2IUDQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	AAA domain	-	-	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
CH3_k127_6359386_0	497964.CfE428DRAFT_1043	6.737e-128	418.0	COG0389@1|root,COG0389@2|Bacteria,46SNK@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
CH3_k127_6359386_1	1122176.KB903539_gene1325	7.248e-125	423.0	COG4886@1|root,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
CH3_k127_6359386_7	1210884.HG799466_gene12517	8.316e-16	87.0	COG4968@1|root,COG4968@2|Bacteria,2J4X1@203682|Planctomycetes	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CH3_k127_6359386_6	452637.Oter_2184	6.114e-24	118.0	COG3291@1|root,COG3291@2|Bacteria,46Z7J@74201|Verrucomicrobia,3KA3F@414999|Opitutae	2|Bacteria	S	SMART Immunoglobulin C2 type	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,He_PIG,Ig_3,VCBS
CH3_k127_6420953_4	1307759.JOMJ01000004_gene2828	4.057e-31	125.0	2C8XG@1|root,2Z7PK@2|Bacteria,1RA5I@1224|Proteobacteria,42QRD@68525|delta/epsilon subdivisions,2WMYW@28221|Deltaproteobacteria,2MC9C@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF4197)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4197
CH3_k127_6420953_0	1267535.KB906767_gene3736	0.0	1061.0	COG0438@1|root,COG0438@2|Bacteria,3Y68X@57723|Acidobacteria	57723|Acidobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CH3_k127_6420953_3	497964.CfE428DRAFT_4858	8.954e-33	132.0	COG0724@1|root,COG0724@2|Bacteria,46VMU@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM RNP-1 like RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
CH3_k127_6420953_1	1158292.JPOE01000002_gene3555	1.578e-56	200.0	COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria,2VHIR@28216|Betaproteobacteria,1KMXP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	Subunit R is required for both nuclease and ATPase activities, but not for modification	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
CH3_k127_6429599_1	111781.Lepto7376_0105	8.063e-41	163.0	COG1520@1|root,COG3210@1|root,COG3595@1|root,COG4995@1|root,COG1520@2|Bacteria,COG3210@2|Bacteria,COG3595@2|Bacteria,COG4995@2|Bacteria,1G08N@1117|Cyanobacteria,1H96Q@1150|Oscillatoriales	1117|Cyanobacteria	U	filamentous hemagglutinin family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,Haemagg_act,P_proprotein
CH3_k127_6429599_0	1116369.KB890025_gene5278	4.195e-242	775.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,1MUXJ@1224|Proteobacteria,2TRGS@28211|Alphaproteobacteria,43NRM@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Belongs to the GcvT family	-	-	1.5.3.19	ko:K19191	ko00760,ko01120,map00760,map01120	-	R10102	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
CH3_k127_6429599_2	521674.Plim_4045	4.617e-40	174.0	2CGJ6@1|root,31UKG@2|Bacteria,2J1GT@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_6440060_1	396588.Tgr7_2069	8.789e-25	107.0	COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,1RMKW@1236|Gammaproteobacteria,1WW5P@135613|Chromatiales	135613|Chromatiales	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
CH3_k127_6440060_2	315456.RF_0905	2.56e-13	77.0	COG2001@1|root,COG2001@2|Bacteria,1RHCG@1224|Proteobacteria,2UD3W@28211|Alphaproteobacteria,47FG2@766|Rickettsiales	766|Rickettsiales	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
CH3_k127_6440060_0	324602.Caur_0763	1.093e-73	258.0	COG0275@1|root,COG0275@2|Bacteria,2G658@200795|Chloroflexi,374SY@32061|Chloroflexia	32061|Chloroflexia	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
CH3_k127_6461956_8	411902.CLOBOL_03557	1.206e-24	106.0	COG2721@1|root,COG2721@2|Bacteria,1TUD7@1239|Firmicutes,24R3M@186801|Clostridia,221BF@1506553|Lachnoclostridium	186801|Clostridia	G	SAF domain	-	-	-	-	-	-	-	-	-	-	-	-	SAF
CH3_k127_6461956_1	1123269.NX02_17320	1.186e-191	606.0	COG2721@1|root,COG2721@2|Bacteria,1MU9V@1224|Proteobacteria,2TTDT@28211|Alphaproteobacteria,2K15R@204457|Sphingomonadales	204457|Sphingomonadales	G	D-galactarate dehydratase / Altronate hydrolase, C terminus	-	-	4.2.1.7	ko:K01685	ko00040,ko01100,map00040,map01100	M00631	R01540	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	GD_AH_C
CH3_k127_6461956_3	1123242.JH636434_gene4153	1.529e-152	492.0	COG4409@1|root,COG4409@2|Bacteria,2J53Z@203682|Planctomycetes	203682|Planctomycetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
CH3_k127_6461956_4	1403819.BATR01000135_gene4812	5.242e-115	380.0	COG0329@1|root,COG0329@2|Bacteria,46UU4@74201|Verrucomicrobia	74201|Verrucomicrobia	EM	Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
CH3_k127_6461956_9	1142394.PSMK_06110	6.072e-13	79.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
CH3_k127_6461956_5	583355.Caka_0956	4.969e-92	319.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C,TAT_signal
CH3_k127_6461956_2	380358.XALC_0037	7.026e-158	511.0	COG2271@1|root,COG2271@2|Bacteria,1MV04@1224|Proteobacteria,1RP70@1236|Gammaproteobacteria,1X56Y@135614|Xanthomonadales	135614|Xanthomonadales	G	Major facilitator superfamily	-	-	-	ko:K08191	-	-	-	-	ko00000,ko02000	2.A.1.14.2	-	-	MFS_1
CH3_k127_6461956_6	42256.RradSPS_2706	5.926e-64	235.0	COG4671@1|root,COG4671@2|Bacteria,2IAST@201174|Actinobacteria	201174|Actinobacteria	S	Glycosyltransferase family 28 C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C
CH3_k127_6461956_0	1173026.Glo7428_4406	8.863e-210	669.0	COG1132@1|root,COG1132@2|Bacteria,1G1JY@1117|Cyanobacteria	1117|Cyanobacteria	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CH3_k127_6461956_7	380394.Lferr_0767	1.012e-26	117.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,1RYBJ@1236|Gammaproteobacteria,2NDM4@225057|Acidithiobacillales	225057|Acidithiobacillales	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
CH3_k127_6468754_3	756272.Plabr_1230	7.412e-09	60.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CH3_k127_6468754_2	886293.Sinac_0289	2.353e-25	109.0	COG3293@1|root,COG3293@2|Bacteria,2IY34@203682|Planctomycetes	203682|Planctomycetes	L	PFAM Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
CH3_k127_6468754_0	1396141.BATP01000057_gene3053	5.534e-194	656.0	COG2312@1|root,COG3209@1|root,COG2312@2|Bacteria,COG3209@2|Bacteria,46XD5@74201|Verrucomicrobia,2IVHX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Fn3_assoc,LTD
CH3_k127_6468754_1	485918.Cpin_7074	2.234e-37	162.0	COG3115@1|root,COG3115@2|Bacteria,4PN8V@976|Bacteroidetes,1J0PP@117747|Sphingobacteriia	976|Bacteroidetes	D	cell septum assembly	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_6547784_3	35128.Thaps23576	2.301e-05	49.0	2ENJE@1|root,2SRZD@2759|Eukaryota,2XGJZ@2836|Bacillariophyta	2836|Bacillariophyta	S	Helicase associated domain	-	-	-	-	-	-	-	-	-	-	-	-	HA
CH3_k127_6547784_0	395494.Galf_2787	1.63e-254	810.0	COG1111@1|root,COG4889@1|root,COG1111@2|Bacteria,COG4889@2|Bacteria,1P17M@1224|Proteobacteria,2WHHU@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Mrr_cat_2
CH3_k127_6547784_2	420324.KI911932_gene324	6.451e-19	90.0	2EHAG@1|root,3394C@2|Bacteria,1NK4E@1224|Proteobacteria,2UJZB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Family of unknown function (DUF5372)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5372
CH3_k127_6547784_1	1366050.N234_27952	3.703e-32	132.0	COG3415@1|root,COG3415@2|Bacteria,1RKUV@1224|Proteobacteria,2WFVI@28216|Betaproteobacteria,1KI6K@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28,HTH_29
CH3_k127_6553154_1	56780.SYN_00176	5.729e-66	246.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,1NPFY@1224|Proteobacteria,42PRW@68525|delta/epsilon subdivisions,2WIMG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	homocysteine S-methyltransferase	metF-2	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0504	MTHFR,S-methyl_trans
CH3_k127_6553154_0	382464.ABSI01000009_gene3973	1.527e-127	425.0	COG0685@1|root,COG0685@2|Bacteria,46TD1@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Methylene-tetrahydrofolate reductase C terminal	-	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,MTHFR_C
CH3_k127_6560113_2	1210884.HG799469_gene14127	8.005e-50	185.0	COG0385@1|root,COG0385@2|Bacteria	2|Bacteria	S	bile acid:sodium symporter activity	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
CH3_k127_6560113_1	56780.SYN_02948	1.504e-72	265.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,42Q4P@68525|delta/epsilon subdivisions,2WJHQ@28221|Deltaproteobacteria,2MR8F@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Biotin-lipoyl like	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
CH3_k127_6560113_0	596151.DesfrDRAFT_3282	3.788e-98	332.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJVV@28221|Deltaproteobacteria,2M817@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family	bepE	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
CH3_k127_6563585_14	1267535.KB906767_gene4118	1.106e-84	288.0	COG0531@1|root,COG0531@2|Bacteria,3Y3GY@57723|Acidobacteria,2JHIT@204432|Acidobacteriia	204432|Acidobacteriia	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease
CH3_k127_6563585_12	1340493.JNIF01000003_gene1731	1.367e-126	425.0	COG3292@1|root,COG3292@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
CH3_k127_6563585_11	1403819.BATR01000092_gene2754	1.43e-131	431.0	COG3174@1|root,COG3174@2|Bacteria,46VTJ@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF4010)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010,MgtC
CH3_k127_6563585_23	86106.I862_01655	7.955e-10	69.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,2TT32@28211|Alphaproteobacteria,47F1D@766|Rickettsiales	766|Rickettsiales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
CH3_k127_6563585_8	1267534.KB906754_gene3770	1.093e-171	553.0	COG1007@1|root,COG1007@2|Bacteria,3Y73U@57723|Acidobacteria,2JMM8@204432|Acidobacteriia	204432|Acidobacteriia	C	Proton-conducting membrane transporter	-	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
CH3_k127_6563585_3	1267534.KB906754_gene3771	1.004e-224	706.0	COG1008@1|root,COG1008@2|Bacteria,3Y6FA@57723|Acidobacteria,2JM6J@204432|Acidobacteriia	204432|Acidobacteriia	C	Proton-conducting membrane transporter	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
CH3_k127_6563585_5	1267534.KB906754_gene3772	1.18e-207	660.0	COG1008@1|root,COG1008@2|Bacteria,3Y6ZF@57723|Acidobacteria,2JMB1@204432|Acidobacteriia	204432|Acidobacteriia	C	Proton-conducting membrane transporter	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
CH3_k127_6563585_0	1267534.KB906754_gene3773	2.718e-294	919.0	COG1009@1|root,COG1009@2|Bacteria,3Y76V@57723|Acidobacteria,2JMJJ@204432|Acidobacteriia	204432|Acidobacteriia	CP	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
CH3_k127_6563585_17	1267534.KB906754_gene3774	4.084e-43	160.0	COG0713@1|root,COG0713@2|Bacteria,3Y835@57723|Acidobacteria,2JN5T@204432|Acidobacteriia	204432|Acidobacteriia	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 4L	-	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
CH3_k127_6563585_16	1267534.KB906754_gene3775	4.71e-46	172.0	COG0839@1|root,COG0839@2|Bacteria,3Y84Z@57723|Acidobacteria,2JN7E@204432|Acidobacteriia	204432|Acidobacteriia	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 6	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
CH3_k127_6563585_9	1267534.KB906754_gene3776	4.101e-164	524.0	COG1005@1|root,COG1005@2|Bacteria,3Y6TS@57723|Acidobacteria,2JKJQ@204432|Acidobacteriia	204432|Acidobacteriia	C	NADH dehydrogenase	-	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
CH3_k127_6563585_13	1267534.KB906754_gene3777	2.955e-88	295.0	COG1143@1|root,COG1143@2|Bacteria,3Y6N6@57723|Acidobacteria,2JKQS@204432|Acidobacteriia	204432|Acidobacteriia	C	4Fe-4S dicluster domain	-	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4_7
CH3_k127_6563585_7	452637.Oter_0755	1.926e-178	571.0	COG1007@1|root,COG1007@2|Bacteria,46W5N@74201|Verrucomicrobia,3K8V4@414999|Opitutae	414999|Opitutae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
CH3_k127_6563585_4	452637.Oter_0754	2.21e-215	681.0	COG1008@1|root,COG1008@2|Bacteria,46SE4@74201|Verrucomicrobia,3K7XF@414999|Opitutae	414999|Opitutae	C	Proton-conducting membrane transporter	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
CH3_k127_6563585_1	452637.Oter_0753	1.92e-282	879.0	COG0651@1|root,COG0651@2|Bacteria,46U4G@74201|Verrucomicrobia,3K7M3@414999|Opitutae	2|Bacteria	C	PFAM NADH Ubiquinone plastoquinone (complex I)	ndhD5	-	1.6.5.3	ko:K05568,ko:K05575	ko00190,ko01100,map00190,map01100	M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko02000	2.A.63.1,2.A.63.2	-	iJN678.ndhD	Proton_antipo_M
CH3_k127_6563585_20	1121413.JMKT01000008_gene1370	2.525e-25	114.0	2BR4E@1|root,32K2C@2|Bacteria,1Q2KP@1224|Proteobacteria,42X9C@68525|delta/epsilon subdivisions,2WSUZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_6563585_2	452637.Oter_0751	9.609e-237	741.0	COG0651@1|root,COG0651@2|Bacteria	2|Bacteria	CP	ATP synthesis coupled electron transport	nuoL2	-	1.6.5.3	ko:K00341,ko:K05568	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko02000	2.A.63.1,2.A.63.2,3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
CH3_k127_6563585_19	452637.Oter_0750	1.802e-36	141.0	COG0713@1|root,COG0713@2|Bacteria	2|Bacteria	C	ATP synthesis coupled electron transport	nuoK	-	1.6.5.3	ko:K00340,ko:K05576	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
CH3_k127_6563585_18	452637.Oter_0749	6.71e-43	163.0	COG0839@1|root,COG0839@2|Bacteria	2|Bacteria	C	Belongs to the complex I subunit 6 family	ndhG	-	1.6.5.3	ko:K00339,ko:K05578	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
CH3_k127_6563585_15	452637.Oter_0748	2.64e-50	193.0	COG1143@1|root,COG1143@2|Bacteria,46YB4@74201|Verrucomicrobia,3K98S@414999|Opitutae	414999|Opitutae	C	4Fe-4S binding domain	-	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
CH3_k127_6563585_10	452637.Oter_0747	1.24e-152	488.0	COG1005@1|root,COG1005@2|Bacteria,46SIJ@74201|Verrucomicrobia,3K82N@414999|Opitutae	414999|Opitutae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	-	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
CH3_k127_6563585_6	452637.Oter_0746	7.986e-190	598.0	COG0649@1|root,COG0649@2|Bacteria,46SA0@74201|Verrucomicrobia,3K8K5@414999|Opitutae	414999|Opitutae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
CH3_k127_6563585_22	452637.Oter_0745	3.649e-20	89.0	COG0852@1|root,COG0852@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
CH3_k127_6581203_7	1380394.JADL01000003_gene4962	1.232e-31	128.0	COG1216@1|root,COG3934@1|root,COG1216@2|Bacteria,COG3934@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9,Cellulase,Glyco_hydro_2_C,Glycos_transf_2
CH3_k127_6581203_8	944479.JQLX01000016_gene325	2.226e-28	120.0	COG2050@1|root,COG2050@2|Bacteria,1N8F8@1224|Proteobacteria,42V78@68525|delta/epsilon subdivisions,2WRBA@28221|Deltaproteobacteria,2M7BC@213113|Desulfurellales	28221|Deltaproteobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
CH3_k127_6581203_6	452637.Oter_0025	8.232e-45	181.0	COG1538@1|root,COG1538@2|Bacteria,46VZS@74201|Verrucomicrobia,3K7CV@414999|Opitutae	414999|Opitutae	MU	PFAM outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
CH3_k127_6581203_1	204669.Acid345_4092	1.861e-82	286.0	COG0009@1|root,COG0009@2|Bacteria,3Y3VW@57723|Acidobacteria,2JHTT@204432|Acidobacteriia	204432|Acidobacteriia	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
CH3_k127_6581203_2	497964.CfE428DRAFT_2629	4.424e-77	271.0	COG0547@1|root,COG0547@2|Bacteria,46SQA@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
CH3_k127_6581203_12	1869.MB27_39975	7.387e-07	62.0	2EGCD@1|root,33A46@2|Bacteria,2HUKV@201174|Actinobacteria,4DFF1@85008|Micromonosporales	201174|Actinobacteria	S	Domain of unknown function (DUF4190)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4190
CH3_k127_6581203_13	1303518.CCALI_02493	3.93e-06	59.0	COG4969@1|root,COG4969@2|Bacteria	2|Bacteria	NU	cell adhesion	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,SBP_bac_10
CH3_k127_6581203_11	452637.Oter_0732	5.936e-10	68.0	COG1714@1|root,COG1714@2|Bacteria	2|Bacteria	S	RDD family	-	-	-	ko:K18481	-	M00670	-	-	ko00000,ko00002,ko02000	3.A.1.27.4,3.A.1.27.5	-	-	DUF2510,FHA,RDD
CH3_k127_6581203_10	1048339.KB913029_gene1929	3.756e-20	101.0	2E37T@1|root,32Y7G@2|Bacteria,2HKTZ@201174|Actinobacteria,4EWSP@85013|Frankiales	201174|Actinobacteria	S	Protein of unknown function (DUF2752)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2752
CH3_k127_6581203_9	426716.JOAJ01000004_gene3022	4.708e-24	104.0	COG2154@1|root,COG2154@2|Bacteria,2IKXR@201174|Actinobacteria,4G30U@85025|Nocardiaceae	201174|Actinobacteria	H	pterin-4-alpha-carbinolamine dehydratase	phhB	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
CH3_k127_6581203_3	1521187.JPIM01000083_gene3839	2.277e-74	265.0	COG0153@1|root,COG0153@2|Bacteria,2G6CE@200795|Chloroflexi,375CJ@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
CH3_k127_6581203_5	1408813.AYMG01000036_gene3246	8.776e-61	215.0	COG0526@1|root,COG0526@2|Bacteria,4PIWE@976|Bacteroidetes,1IYSU@117747|Sphingobacteriia	976|Bacteroidetes	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_6581203_0	243090.RB8979	1.38e-178	575.0	COG1760@1|root,COG1760@2|Bacteria	2|Bacteria	E	l-serine dehydratase	-	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha,SDH_beta
CH3_k127_6581203_4	452637.Oter_4517	2.265e-63	233.0	COG0673@1|root,COG0673@2|Bacteria,46UJR@74201|Verrucomicrobia,3K94Y@414999|Opitutae	2|Bacteria	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CH3_k127_6586602_7	452637.Oter_0358	0.0008767	48.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,46YZC@74201|Verrucomicrobia,3K9WB@414999|Opitutae	414999|Opitutae	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CH3_k127_6586602_0	497964.CfE428DRAFT_0066	1.151e-43	163.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,46TTW@74201|Verrucomicrobia	74201|Verrucomicrobia	KLT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PEGA,Pkinase
CH3_k127_6586602_1	382464.ABSI01000011_gene2968	2.069e-30	128.0	COG0515@1|root,COG0515@2|Bacteria	382464.ABSI01000011_gene2968|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_6586602_4	306281.AJLK01000102_gene3405	7.211e-09	60.0	COG2258@1|root,COG2258@2|Bacteria,1GE7I@1117|Cyanobacteria	1117|Cyanobacteria	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_6586602_6	390235.PputW619_4524	0.000186	48.0	COG4974@1|root,COG4974@2|Bacteria,1MZES@1224|Proteobacteria,1S9MN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Plasmid pRiA4b ORF-3-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3
CH3_k127_6586602_5	468059.AUHA01000003_gene1581	1.836e-05	60.0	COG3386@1|root,COG3391@1|root,COG4625@1|root,COG5492@1|root,COG3386@2|Bacteria,COG3391@2|Bacteria,COG4625@2|Bacteria,COG5492@2|Bacteria,4NK33@976|Bacteroidetes,1IX26@117747|Sphingobacteriia	976|Bacteroidetes	G	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG
CH3_k127_6586602_3	357808.RoseRS_4272	2.656e-11	79.0	COG2931@1|root,COG3210@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,2G88I@200795|Chloroflexi,3780V@32061|Chloroflexia	32061|Chloroflexia	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_6586602_2	459495.SPLC1_S470080	3.004e-25	125.0	COG2931@1|root,COG4675@1|root,COG2931@2|Bacteria,COG4675@2|Bacteria,1GFPS@1117|Cyanobacteria,1HHVN@1150|Oscillatoriales	1117|Cyanobacteria	Q	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
CH3_k127_659995_0	272123.Anacy_4407	7.956e-90	336.0	COG2931@1|root,COG5276@1|root,COG2931@2|Bacteria,COG5276@2|Bacteria,1GQ7S@1117|Cyanobacteria,1HRXM@1161|Nostocales	1117|Cyanobacteria	Q	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,DUF4347,HemolysinCabind,LVIVD
CH3_k127_659995_1	498761.HM1_0137	3.096e-23	118.0	COG1470@1|root,COG3210@1|root,COG4733@1|root,COG4886@1|root,COG5492@1|root,COG1470@2|Bacteria,COG3210@2|Bacteria,COG4733@2|Bacteria,COG4886@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_2,CHU_C,Flg_new,LRR_5,RCC1,SLH
CH3_k127_659995_2	641526.ADIWIN_2870	7.928e-16	93.0	COG3210@1|root,COG3210@2|Bacteria,4NGEX@976|Bacteroidetes,1HZV9@117743|Flavobacteriia	976|Bacteroidetes	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_664531_2	316274.Haur_3147	1.632e-07	64.0	COG1668@1|root,COG1668@2|Bacteria,2GBIJ@200795|Chloroflexi,3768Z@32061|Chloroflexia	32061|Chloroflexia	CP	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2,ABC2_membrane_3
CH3_k127_664531_1	1210884.HG799464_gene11092	2.055e-15	89.0	COG1668@1|root,COG1668@2|Bacteria,2IXFE@203682|Planctomycetes	203682|Planctomycetes	CP	transmembrane transport	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2,ABC2_membrane_3
CH3_k127_664531_3	1229780.BN381_350147	2.493e-07	63.0	COG1668@1|root,COG1668@2|Bacteria	2|Bacteria	CP	transmembrane transport	-	-	-	ko:K01992,ko:K09696	ko02010,ko02020,map02010,map02020	M00253,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.115	-	-	ABC2_membrane,ABC2_membrane_2,ABC2_membrane_3
CH3_k127_664531_4	58123.JOFJ01000024_gene3453	0.0003818	53.0	COG1277@1|root,COG1277@2|Bacteria,2IIXQ@201174|Actinobacteria	201174|Actinobacteria	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
CH3_k127_664531_0	1123508.JH636439_gene1556	4.238e-69	242.0	COG1131@1|root,COG1131@2|Bacteria,2IXFI@203682|Planctomycetes	203682|Planctomycetes	V	ABC-type multidrug transport system ATPase	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CH3_k127_6647933_24	1210884.HG799467_gene13206	5.988e-24	102.0	COG0205@1|root,COG0205@2|Bacteria,2IXXF@203682|Planctomycetes	203682|Planctomycetes	G	Phosphofructokinase	-	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
CH3_k127_6647933_4	497964.CfE428DRAFT_3906	1.324e-144	464.0	COG0039@1|root,COG0039@2|Bacteria,46SC4@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
CH3_k127_6647933_11	1121104.AQXH01000001_gene1195	2.504e-90	306.0	COG1012@1|root,COG1012@2|Bacteria,4NZV1@976|Bacteroidetes	976|Bacteroidetes	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
CH3_k127_6647933_20	1205680.CAKO01000002_gene2136	1.756e-34	147.0	COG3848@1|root,COG3848@2|Bacteria,1R7DS@1224|Proteobacteria,2U3SK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Pyruvate phosphate dikinase	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_6647933_23	1123073.KB899242_gene1109	3.034e-25	124.0	COG1470@1|root,COG3210@1|root,COG4625@1|root,COG5492@1|root,COG1470@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria,COG5492@2|Bacteria,1QUXB@1224|Proteobacteria	1224|Proteobacteria	U	6-phosphogluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,DUF4347,Haemagg_act,He_PIG,Hint_2,TIG
CH3_k127_6647933_27	153721.MYP_567	7.018e-15	85.0	COG3291@1|root,COG4099@1|root,COG5295@1|root,COG5297@1|root,COG3291@2|Bacteria,COG4099@2|Bacteria,COG5295@2|Bacteria,COG5297@2|Bacteria,4NF6Q@976|Bacteroidetes,47KN7@768503|Cytophagia	976|Bacteroidetes	GUW	candidate b-glycosidase, glycoside hydrolase family 8 protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_3_3,M60-like_N,NosD,Peptidase_M60
CH3_k127_6647933_26	675814.VIC_000680	4.89e-16	89.0	COG3469@1|root,COG3979@1|root,COG3469@2|Bacteria,COG3979@2|Bacteria,1MUUS@1224|Proteobacteria,1RYTJ@1236|Gammaproteobacteria,1XUGW@135623|Vibrionales	135623|Vibrionales	G	Glycosyl hydrolases family 18	chiA	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	Glyco_hydro_18
CH3_k127_6647933_2	497964.CfE428DRAFT_3146	1.017e-239	758.0	COG0028@1|root,COG0028@2|Bacteria,46S72@74201|Verrucomicrobia	74201|Verrucomicrobia	EH	thiamine pyrophosphate protein TPP binding domain protein	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CH3_k127_6647933_13	497964.CfE428DRAFT_3392	5.916e-72	254.0	COG3828@1|root,COG3828@2|Bacteria,46UCF@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
CH3_k127_6647933_8	1303518.CCALI_00783	2.2e-96	337.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CH3_k127_6647933_29	866536.Belba_2664	3.218e-11	74.0	COG2353@1|root,COG2353@2|Bacteria,4NQKY@976|Bacteroidetes,47RR5@768503|Cytophagia	976|Bacteroidetes	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
CH3_k127_6647933_28	518766.Rmar_0433	3.662e-12	76.0	COG2353@1|root,COG2353@2|Bacteria,4PBAH@976|Bacteroidetes,1FK7G@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
CH3_k127_6647933_15	1121374.KB891580_gene1807	1.611e-69	243.0	COG2199@1|root,COG3706@2|Bacteria,1N2X1@1224|Proteobacteria,1SU4M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Carbohydrate-binding family 9	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_2
CH3_k127_6647933_18	1123368.AUIS01000004_gene217	3.257e-45	169.0	COG1666@1|root,COG1666@2|Bacteria,1RDTF@1224|Proteobacteria,1S3RU@1236|Gammaproteobacteria,2NCB7@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Belongs to the UPF0234 family	-	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
CH3_k127_6647933_10	497964.CfE428DRAFT_6354	2.821e-92	309.0	COG0125@1|root,COG0125@2|Bacteria	2|Bacteria	F	dTDP biosynthetic process	tmk	GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.1.1.45,2.7.4.9,4.1.1.19	ko:K00560,ko:K00943,ko:K01585	ko00240,ko00330,ko00670,ko01100,ko01523,map00240,map00330,map00670,map01100,map01523	M00053,M00133	R00566,R02094,R02098,R02101	RC00002,RC00219,RC00299,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS00680,iJN746.PP_3363,iNJ661.Rv3247c	AAA_33,Thymidylate_kin
CH3_k127_6647933_12	497964.CfE428DRAFT_6353	7.236e-82	281.0	COG0125@1|root,COG0125@2|Bacteria	2|Bacteria	F	dTDP biosynthetic process	tmk	GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.4.9,4.1.1.19	ko:K00943,ko:K01585	ko00240,ko00330,ko01100,map00240,map00330,map01100	M00053,M00133	R00566,R02094,R02098	RC00002,RC00299	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS00680,iJN746.PP_3363,iNJ661.Rv3247c	AAA_33,Thymidylate_kin
CH3_k127_6647933_14	509191.AEDB02000067_gene820	3.99e-71	252.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia,3WHXD@541000|Ruminococcaceae	186801|Clostridia	GK	ROK family	glcK	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10220	ROK
CH3_k127_6647933_22	1459636.NTE_00049	8.812e-28	119.0	COG2062@1|root,arCOG01992@2157|Archaea	2157|Archaea	T	TIGRFAM phosphohistidine phosphatase SixA	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
CH3_k127_6647933_25	857087.Metme_0945	1.096e-16	90.0	COG5607@1|root,COG5607@2|Bacteria	2|Bacteria	F	PFAM CHAD domain containing protein	sixA-2	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	CHAD,His_Phos_1
CH3_k127_6647933_0	497964.CfE428DRAFT_4539	6.602e-295	921.0	COG0855@1|root,COG0855@2|Bacteria,46SB4@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
CH3_k127_6647933_19	1089549.AZUQ01000001_gene203	4.071e-43	170.0	COG0248@1|root,COG0248@2|Bacteria,2GJBN@201174|Actinobacteria,4EXWS@85014|Glycomycetales	201174|Actinobacteria	FP	Ppx/GppA phosphatase family	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
CH3_k127_6647933_3	886293.Sinac_2390	2.679e-231	728.0	COG3119@1|root,COG3119@2|Bacteria,2IYRK@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CH3_k127_6647933_30	696747.NIES39_O06680	3.713e-10	72.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
CH3_k127_6647933_9	575540.Isop_2533	3.723e-96	321.0	COG3485@1|root,COG3485@2|Bacteria,2IYK6@203682|Planctomycetes	203682|Planctomycetes	Q	PFAM intradiol ring-cleavage dioxygenase	-	-	1.13.11.3	ko:K00449	ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220	-	R01631,R03549	RC00388,RC00953	br01602,ko00000,ko00001,ko01000	-	-	-	Dioxygenase_C
CH3_k127_6647933_6	521674.Plim_3842	5.193e-102	340.0	COG0412@1|root,COG0412@2|Bacteria	2|Bacteria	Q	carboxymethylenebutenolidase activity	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
CH3_k127_6647933_1	497964.CfE428DRAFT_5375	3.487e-247	786.0	COG0457@1|root,COG1225@1|root,COG0457@2|Bacteria,COG1225@2|Bacteria,46U46@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CH3_k127_6647933_31	768670.Calni_0018	0.0005322	49.0	COG0296@1|root,COG0296@2|Bacteria,2GFUK@200930|Deferribacteres	200930|Deferribacteres	G	Carbohydrate-binding module 48 (Isoamylase N-terminal domain)	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM
CH3_k127_6647933_17	329726.AM1_4632	7.937e-57	209.0	COG3735@1|root,COG3735@2|Bacteria,1G6DE@1117|Cyanobacteria	1117|Cyanobacteria	S	TraB family	-	-	-	ko:K09973	-	-	-	-	ko00000	-	-	-	TraB
CH3_k127_6647933_7	1396418.BATQ01000056_gene181	1.736e-99	335.0	COG4188@1|root,COG4188@2|Bacteria,46TTD@74201|Verrucomicrobia,2IVPV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Platelet-activating factor acetylhydrolase, isoform II	-	-	-	-	-	-	-	-	-	-	-	-	PAF-AH_p_II
CH3_k127_6647933_5	1123242.JH636435_gene1598	1.902e-106	354.0	COG2120@1|root,COG2120@2|Bacteria,2IY80@203682|Planctomycetes	203682|Planctomycetes	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
CH3_k127_6647933_16	314230.DSM3645_05180	1.366e-65	248.0	COG2159@1|root,COG2159@2|Bacteria,2IYMW@203682|Planctomycetes	203682|Planctomycetes	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CH3_k127_6647933_21	1267535.KB906767_gene1160	4.392e-29	135.0	COG2006@1|root,COG2006@2|Bacteria,3Y7N1@57723|Acidobacteria,2JNKP@204432|Acidobacteriia	204432|Acidobacteriia	S	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
CH3_k127_6651606_1	96561.Dole_1704	7.348e-17	94.0	COG3420@1|root,COG3420@2|Bacteria,1MZHI@1224|Proteobacteria,43BRC@68525|delta/epsilon subdivisions,2WUM4@28221|Deltaproteobacteria,2MN6K@213118|Desulfobacterales	1224|Proteobacteria	P	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_6651606_0	498761.HM1_0137	2.623e-29	135.0	COG1470@1|root,COG3210@1|root,COG4733@1|root,COG4886@1|root,COG5492@1|root,COG1470@2|Bacteria,COG3210@2|Bacteria,COG4733@2|Bacteria,COG4886@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_2,CHU_C,Flg_new,LRR_5,RCC1,SLH
CH3_k127_6651606_3	1047013.AQSP01000122_gene2233	3.561e-13	82.0	COG2755@1|root,COG2755@2|Bacteria,2NR42@2323|unclassified Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL,Lipase_GDSL_2
CH3_k127_6651606_4	1521187.JPIM01000047_gene117	1.242e-05	49.0	COG3293@1|root,COG3293@2|Bacteria,2G7YC@200795|Chloroflexi	200795|Chloroflexi	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
CH3_k127_6683739_7	313628.LNTAR_00520	2.376e-07	61.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CH3_k127_6683739_6	1210884.HG799466_gene12517	9.608e-12	75.0	COG4968@1|root,COG4968@2|Bacteria,2J4X1@203682|Planctomycetes	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CH3_k127_6683739_4	497964.CfE428DRAFT_3684	4.488e-30	124.0	COG0071@1|root,COG0071@2|Bacteria,46WRX@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	-	-	-	-	-	-	-	-	-	HSP20
CH3_k127_6683739_2	497964.CfE428DRAFT_3685	5.498e-44	165.0	COG0071@1|root,COG0071@2|Bacteria,46T3G@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Belongs to the small heat shock protein (HSP20) family	ibpA	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
CH3_k127_6683739_1	1499967.BAYZ01000088_gene5090	1.052e-110	367.0	COG0191@1|root,COG0191@2|Bacteria,2NPSG@2323|unclassified Bacteria	2|Bacteria	G	Fructose-bisphosphate aldolase class-II	fba	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
CH3_k127_6683739_0	497964.CfE428DRAFT_3562	3.899e-129	424.0	COG1459@1|root,COG1459@2|Bacteria,46S5B@74201|Verrucomicrobia	74201|Verrucomicrobia	U	PFAM type II secretion system	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
CH3_k127_6683739_5	481448.Minf_0089	6.538e-16	91.0	2ADRD@1|root,313GQ@2|Bacteria,46ZIR@74201|Verrucomicrobia,37GDJ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Putative beta-barrel porin-2, OmpL-like. bbp2	-	-	-	-	-	-	-	-	-	-	-	-	BBP2
CH3_k127_670029_6	497964.CfE428DRAFT_2283	4.239e-28	117.0	COG2331@1|root,COG2331@2|Bacteria,46T2S@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
CH3_k127_670029_1	1396141.BATP01000003_gene5199	8.261e-171	546.0	COG1509@1|root,COG1509@2|Bacteria,46SVQ@74201|Verrucomicrobia,2ITNU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Lysine-2,3-aminomutase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,LAM_C,Radical_SAM
CH3_k127_670029_3	1396418.BATQ01000136_gene3705	3.452e-91	314.0	COG1502@1|root,COG1502@2|Bacteria,46U9X@74201|Verrucomicrobia,2ITQD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Phospholipase D. Active site motifs.	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
CH3_k127_670029_4	1051632.TPY_0383	7.052e-56	207.0	COG2912@1|root,COG2912@2|Bacteria,1VXJ8@1239|Firmicutes,25294@186801|Clostridia	186801|Clostridia	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core2
CH3_k127_670029_5	497964.CfE428DRAFT_4835	1.991e-43	161.0	COG4747@1|root,COG4747@2|Bacteria,46WIS@74201|Verrucomicrobia	74201|Verrucomicrobia	S	ACT domain	-	-	-	-	-	-	-	-	-	-	-	-	ACT
CH3_k127_670029_2	1156844.KB891831_gene4705	6.347e-119	399.0	COG0366@1|root,COG0366@2|Bacteria,2GN52@201174|Actinobacteria	201174|Actinobacteria	G	Alpha amylase catalytic	amyA	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase
CH3_k127_670029_0	903818.KI912268_gene806	5.205e-204	650.0	COG0067@1|root,COG0069@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,3Y2JQ@57723|Acidobacteria	57723|Acidobacteria	E	glutamate synthase alpha subunit	-	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
CH3_k127_6706072_0	926550.CLDAP_04870	9.463e-69	247.0	COG2133@1|root,COG2133@2|Bacteria,2G62S@200795|Chloroflexi	200795|Chloroflexi	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
CH3_k127_6706072_1	1123242.JH636434_gene3261	0.0006341	44.0	2E02K@1|root,32KJE@2|Bacteria,2J430@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_6723156_1	504472.Slin_2796	1.539e-103	349.0	COG3669@1|root,COG3669@2|Bacteria,4NE74@976|Bacteroidetes,47KQM@768503|Cytophagia	976|Bacteroidetes	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,F5_F8_type_C
CH3_k127_6723156_0	1121011.AUCB01000042_gene786	8.584e-149	484.0	COG3669@1|root,COG3669@2|Bacteria,4NE74@976|Bacteroidetes,1IG0A@117743|Flavobacteriia,23IC9@178469|Arenibacter	976|Bacteroidetes	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,F5_F8_type_C
CH3_k127_6736691_4	497964.CfE428DRAFT_1905	1.035e-107	358.0	COG1045@1|root,COG1045@2|Bacteria,46S5J@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Bacterial transferase hexapeptide (six repeats)	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
CH3_k127_6736691_8	477641.MODMU_0790	2.278e-07	55.0	COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,2I81M@201174|Actinobacteria	201174|Actinobacteria	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3,HTH_31
CH3_k127_6736691_9	1121287.AUMU01000010_gene1804	6.579e-05	57.0	COG3210@1|root,COG3210@2|Bacteria,4NTNN@976|Bacteroidetes,1IKPF@117743|Flavobacteriia	976|Bacteroidetes	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,LTD
CH3_k127_6736691_10	9713.XP_006733312.1	0.0001981	55.0	KOG0613@1|root,KOG4475@1|root,KOG0613@2759|Eukaryota,KOG4475@2759|Eukaryota,38BAS@33154|Opisthokonta,3B9IR@33208|Metazoa,3CRJW@33213|Bilateria,484DC@7711|Chordata,48Y8I@7742|Vertebrata,3J1H6@40674|Mammalia,3EFX2@33554|Carnivora	33208|Metazoa	T	Titin Z	TTN	GO:0000070,GO:0000228,GO:0000278,GO:0000280,GO:0000793,GO:0000794,GO:0000819,GO:0001701,GO:0001756,GO:0001932,GO:0002020,GO:0002576,GO:0002791,GO:0002793,GO:0003002,GO:0003007,GO:0003008,GO:0003012,GO:0003013,GO:0003015,GO:0003300,GO:0003674,GO:0003779,GO:0003824,GO:0004672,GO:0004674,GO:0004713,GO:0005198,GO:0005200,GO:0005488,GO:0005509,GO:0005515,GO:0005516,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0005829,GO:0005856,GO:0005859,GO:0005865,GO:0006323,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006928,GO:0006936,GO:0006941,GO:0006996,GO:0007010,GO:0007015,GO:0007049,GO:0007059,GO:0007076,GO:0007154,GO:0007165,GO:0007275,GO:0007389,GO:0007399,GO:0007417,GO:0007420,GO:0007507,GO:0007512,GO:0007517,GO:0008015,GO:0008092,GO:0008150,GO:0008152,GO:0008307,GO:0009581,GO:0009582,GO:0009605,GO:0009612,GO:0009628,GO:0009653,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009893,GO:0009952,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010604,GO:0010628,GO:0010737,GO:0010927,GO:0014706,GO:0014866,GO:0014896,GO:0014897,GO:0015629,GO:0016043,GO:0016192,GO:0016301,GO:0016310,GO:0016459,GO:0016460,GO:0016740,GO:0016772,GO:0016773,GO:0018108,GO:0018193,GO:0018212,GO:0019220,GO:0019222,GO:0019538,GO:0019899,GO:0019900,GO:0019901,GO:0021591,GO:0022402,GO:0022607,GO:0023052,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030036,GO:0030048,GO:0030049,GO:0030154,GO:0030239,GO:0030240,GO:0030241,GO:0030261,GO:0030506,GO:0031032,GO:0031033,GO:0031034,GO:0031323,GO:0031399,GO:0031430,GO:0031433,GO:0031672,GO:0031674,GO:0031974,GO:0031981,GO:0032268,GO:0032501,GO:0032502,GO:0032879,GO:0032880,GO:0032940,GO:0032989,GO:0032991,GO:0033058,GO:0033275,GO:0034622,GO:0035051,GO:0035265,GO:0035282,GO:0035556,GO:0035994,GO:0035995,GO:0036211,GO:0036379,GO:0040007,GO:0040011,GO:0042221,GO:0042325,GO:0042692,GO:0042802,GO:0042805,GO:0043009,GO:0043056,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043292,GO:0043412,GO:0043549,GO:0043621,GO:0043933,GO:0044057,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044449,GO:0044464,GO:0044877,GO:0045055,GO:0045214,GO:0045859,GO:0046872,GO:0046903,GO:0048285,GO:0048468,GO:0048513,GO:0048518,GO:0048522,GO:0048589,GO:0048644,GO:0048646,GO:0048729,GO:0048731,GO:0048738,GO:0048739,GO:0048747,GO:0048769,GO:0048856,GO:0048869,GO:0050708,GO:0050714,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0050982,GO:0051015,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051146,GO:0051171,GO:0051174,GO:0051179,GO:0051222,GO:0051223,GO:0051234,GO:0051239,GO:0051246,GO:0051276,GO:0051338,GO:0051371,GO:0051393,GO:0051592,GO:0051606,GO:0051716,GO:0055001,GO:0055002,GO:0055003,GO:0055006,GO:0055007,GO:0055008,GO:0055013,GO:0060047,GO:0060048,GO:0060255,GO:0060322,GO:0060415,GO:0060419,GO:0060429,GO:0060537,GO:0061053,GO:0061061,GO:0065003,GO:0065007,GO:0065009,GO:0070013,GO:0070201,GO:0070252,GO:0070925,GO:0071103,GO:0071688,GO:0071704,GO:0071840,GO:0072359,GO:0080090,GO:0090087,GO:0090257,GO:0097435,GO:0097493,GO:0098813,GO:0099080,GO:0099081,GO:0099512,GO:0140014,GO:0140096,GO:1901077,GO:1901564,GO:1901897,GO:1903047,GO:1903530,GO:1903532,GO:1904951	2.7.11.1	ko:K12567	ko05410,ko05414,map05410,map05414	-	-	-	ko00000,ko00001,ko01000,ko01001,ko04131,ko04147,ko04812	-	-	-	I-set,Ig_2,Ig_3,PPAK,Pkinase,Titin_Z,fn3,ig
CH3_k127_6736691_11	4555.Si032031m	0.0009014	46.0	COG1233@1|root,2QSIC@2759|Eukaryota,37N2T@33090|Viridiplantae,3GBKK@35493|Streptophyta,3KNEA@4447|Liliopsida,3ID4Z@38820|Poales	35493|Streptophyta	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
CH3_k127_6736691_2	880073.Calab_3508	3.014e-122	402.0	COG1446@1|root,COG1446@2|Bacteria,2NPFC@2323|unclassified Bacteria	2|Bacteria	E	Asparaginase	asnA2	GO:0005575,GO:0005623,GO:0042597,GO:0044464	3.4.19.5,3.5.1.1,3.5.1.26	ko:K01424,ko:K01444,ko:K13051	ko00250,ko00460,ko00511,ko01100,ko01110,ko04142,map00250,map00460,map00511,map01100,map01110,map04142	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000,ko01002	-	-	-	Asparaginase_2
CH3_k127_6736691_3	595460.RRSWK_04420	2.242e-119	400.0	COG1070@1|root,COG1070@2|Bacteria,2IXYW@203682|Planctomycetes	203682|Planctomycetes	G	COG1070 Sugar (pentulose and hexulose)	-	-	2.7.1.5	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01902,R03014	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
CH3_k127_6736691_0	497964.CfE428DRAFT_2425	0.0	1474.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,46U71@74201|Verrucomicrobia	74201|Verrucomicrobia	CG	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DUF1080,HEAT_2,Laminin_G_3
CH3_k127_6736691_1	1173026.Glo7428_4012	2.488e-148	486.0	COG3119@1|root,COG3119@2|Bacteria,1G5IZ@1117|Cyanobacteria	1117|Cyanobacteria	P	Arylsulfatase a	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	DUF4976,Sulfatase,Sulfatase_C
CH3_k127_6736691_6	1182553.XP_007740985.1	1.858e-14	87.0	2EX73@1|root,2SYX9@2759|Eukaryota,3A366@33154|Opisthokonta,3P2YI@4751|Fungi,3QU7S@4890|Ascomycota	4751|Fungi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_6736691_7	102232.GLO73106DRAFT_00036360	2.546e-08	67.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF5122,FG-GAP,HemolysinCabind
CH3_k127_6809468_4	1303518.CCALI_00933	6.578e-12	74.0	COG4537@1|root,COG4537@2|Bacteria	2|Bacteria	U	Required for transformation and DNA binding	comGC	GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944	-	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	M00331,M00429	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
CH3_k127_6809468_6	247490.KSU1_C1333	2.315e-10	70.0	COG4968@1|root,COG4968@2|Bacteria,2J519@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CH3_k127_6809468_2	1396141.BATP01000060_gene4563	1.757e-71	262.0	COG0457@1|root,COG0457@2|Bacteria,46W3Y@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3,TPR_16
CH3_k127_6809468_8	1341181.FLJC2902T_10060	1.17e-05	59.0	COG3291@1|root,COG4412@1|root,COG3291@2|Bacteria,COG4412@2|Bacteria,4NG09@976|Bacteroidetes,1HY3Z@117743|Flavobacteriia,2NU61@237|Flavobacterium	976|Bacteroidetes	O	Fungalysin metallopeptidase (M36)	-	-	-	-	-	-	-	-	-	-	-	-	FTP,PA,PKD,Peptidase_M36
CH3_k127_6809468_5	661478.OP10G_0968	9.366e-12	77.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02650,ko:K02679	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10
CH3_k127_6809468_3	1396418.BATQ01000168_gene1787	2.508e-29	130.0	COG2197@1|root,COG2197@2|Bacteria,46UBU@74201|Verrucomicrobia	74201|Verrucomicrobia	T	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CH3_k127_6809468_1	761193.Runsl_3999	4.643e-135	439.0	COG1082@1|root,COG1082@2|Bacteria,4NKFY@976|Bacteroidetes,47N9K@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CH3_k127_6809468_0	706587.Desti_0932	1.961e-148	488.0	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,42MAP@68525|delta/epsilon subdivisions,2WIYI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM Sodium sulphate symporter	sdcS	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
CH3_k127_6809468_7	1396141.BATP01000034_gene4149	2.753e-10	61.0	COG4260@1|root,COG4260@2|Bacteria,46UVR@74201|Verrucomicrobia,2IV4M@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,HTH_17
CH3_k127_6816189_12	575540.Isop_1252	1.227e-46	176.0	COG0673@1|root,COG0673@2|Bacteria,2IXJ0@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CH3_k127_6816189_16	1385935.N836_03200	1.271e-11	76.0	COG2207@1|root,COG2207@2|Bacteria,1GBJH@1117|Cyanobacteria	1117|Cyanobacteria	K	transcriptional	-	-	-	ko:K07506	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18,Response_reg
CH3_k127_6816189_15	661478.OP10G_4770	3.169e-15	87.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CH3_k127_6816189_3	525904.Tter_1997	4.311e-125	409.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CH3_k127_6816189_0	1123508.JH636448_gene7659	5.93e-232	726.0	COG2730@1|root,COG2730@2|Bacteria,2IZBB@203682|Planctomycetes	203682|Planctomycetes	G	Protein of unknown function (DUF4038)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF4038,DUF5060
CH3_k127_6816189_7	344747.PM8797T_05400	3.793e-87	304.0	COG1520@1|root,COG1520@2|Bacteria,2IY8V@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
CH3_k127_6816189_6	1122917.KB899667_gene3587	8.99e-97	328.0	COG2085@1|root,COG2085@2|Bacteria,1TWYH@1239|Firmicutes	1239|Firmicutes	S	Phosphogluconate dehydrogenase (decarboxylating) C-term	-	-	-	-	-	-	-	-	-	-	-	-	IlvN,PGDH_C
CH3_k127_6816189_10	761193.Runsl_3634	3.994e-75	261.0	COG1082@1|root,COG1082@2|Bacteria,4NPBS@976|Bacteroidetes,47Q6G@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CH3_k127_6816189_8	1089551.KE386572_gene1625	3.168e-84	294.0	COG1879@1|root,COG1879@2|Bacteria,1QJ9B@1224|Proteobacteria,2U8ZS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Periplasmic binding protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_4
CH3_k127_6816189_13	35754.JNYJ01000079_gene4336	2.986e-45	181.0	COG1172@1|root,COG1172@2|Bacteria,2GJDW@201174|Actinobacteria,4DDXV@85008|Micromonosporales	201174|Actinobacteria	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
CH3_k127_6816189_2	1089551.KE386572_gene1627	1.767e-165	545.0	COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,2TQJV@28211|Alphaproteobacteria,4BR8I@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	G	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
CH3_k127_6816189_9	1089551.KE386572_gene1628	3.069e-81	283.0	COG1172@1|root,COG1172@2|Bacteria,1MX7D@1224|Proteobacteria,2TV15@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10440,ko:K17203	ko02010,map02010	M00212,M00590	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.11,3.A.1.2.13,3.A.1.2.16,3.A.1.2.19	-	-	BPD_transp_2
CH3_k127_6816189_4	525904.Tter_2007	1.297e-124	424.0	2CB42@1|root,2Z7Y3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_6816189_11	761193.Runsl_3635	1.266e-74	263.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	HemolysinCabind,PD40
CH3_k127_6816189_14	926550.CLDAP_31990	7.008e-40	159.0	COG1082@1|root,COG1082@2|Bacteria,2G7PW@200795|Chloroflexi	200795|Chloroflexi	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CH3_k127_6816189_1	1267533.KB906739_gene2717	3.91e-231	737.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid_C,Bgal_small_N,Glyco_hydro_2,Glyco_hydro_28,Glyco_hydro_2_C,Glyco_hydro_2_N,fn3
CH3_k127_6816189_5	616991.JPOO01000003_gene29	1.61e-99	341.0	2DDE1@1|root,2ZHNZ@2|Bacteria,4NNSM@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
CH3_k127_6821205_5	1122604.JONR01000006_gene2730	4.354e-53	193.0	COG0494@1|root,COG0494@2|Bacteria,1RI3B@1224|Proteobacteria,1S6HR@1236|Gammaproteobacteria,1X60F@135614|Xanthomonadales	135614|Xanthomonadales	L	DNA mismatch repair protein MutT	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
CH3_k127_6821205_3	583355.Caka_1932	8.481e-100	338.0	COG4398@1|root,COG4398@2|Bacteria,46SM5@74201|Verrucomicrobia	74201|Verrucomicrobia	S	FIST_C	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
CH3_k127_6821205_0	497964.CfE428DRAFT_2417	5.361e-162	517.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	SGL
CH3_k127_6821205_4	1396141.BATP01000006_gene5486	3.635e-62	216.0	2DHFW@1|root,2ZZKM@2|Bacteria,46SNY@74201|Verrucomicrobia,2IVW8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_6821205_7	1403819.BATR01000033_gene1102	1.742e-15	80.0	COG1526@1|root,COG1526@2|Bacteria,46SPA@74201|Verrucomicrobia,2IUBY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	FdhD/NarQ family	-	-	-	-	-	-	-	-	-	-	-	-	FdhD-NarQ
CH3_k127_6821205_6	497964.CfE428DRAFT_5396	4.82e-36	142.0	2DQE3@1|root,3368V@2|Bacteria,46WIA@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_6821205_8	1128912.GMES_3098	3.512e-10	70.0	COG3537@1|root,COG3537@2|Bacteria,1R4VD@1224|Proteobacteria,1RZJ5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	F5/8 type C domain	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C
CH3_k127_6821205_1	497964.CfE428DRAFT_2419	4.99e-125	406.0	COG2084@1|root,COG2084@2|Bacteria,46S95@74201|Verrucomicrobia	74201|Verrucomicrobia	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_11,NAD_binding_2
CH3_k127_6821205_2	1123242.JH636434_gene4856	2.589e-124	409.0	COG0591@1|root,COG0591@2|Bacteria,2J2KC@203682|Planctomycetes	203682|Planctomycetes	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
CH3_k127_6832940_0	1396141.BATP01000006_gene5432	1.877e-204	669.0	COG2312@1|root,COG2885@1|root,COG3209@1|root,COG3210@1|root,COG2312@2|Bacteria,COG2885@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,46XSC@74201|Verrucomicrobia,2IWGQ@203494|Verrucomicrobiae	2|Bacteria	M	CotH kinase protein	-	-	-	ko:K02487,ko:K12543	ko02020,map02020	M00330,M00507	-	-	ko00000,ko00001,ko00002,ko02000,ko02022,ko02035,ko02044	1.B.17,3.A.1.109.4	-	-	CotH,Erythro_esteras,LTD,OmpA
CH3_k127_6832940_2	1156937.MFUM_290037	3.396e-65	226.0	COG0440@1|root,COG0440@2|Bacteria,46SUP@74201|Verrucomicrobia,37GJ7@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	E	ACT domain	ilvH	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
CH3_k127_6832940_1	452637.Oter_3478	4.096e-196	616.0	COG0059@1|root,COG0059@2|Bacteria,46SI2@74201|Verrucomicrobia,3K7PK@414999|Opitutae	74201|Verrucomicrobia	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
CH3_k127_6832940_3	440512.C211_12597	4.827e-39	166.0	COG1450@1|root,COG3147@1|root,COG1450@2|Bacteria,COG3147@2|Bacteria,1MUUA@1224|Proteobacteria,1RPJS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	General Secretion Pathway protein	gspD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	SPOR,Secretin,Secretin_N
CH3_k127_6833018_2	497964.CfE428DRAFT_5224	2.301e-136	474.0	COG1473@1|root,COG1473@2|Bacteria,46V61@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
CH3_k127_6833018_1	1121468.AUBR01000038_gene1965	1.475e-142	493.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1TR8J@1239|Firmicutes,247RR@186801|Clostridia,42HW6@68295|Thermoanaerobacterales	186801|Clostridia	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
CH3_k127_6833018_0	886293.Sinac_7036	5.404e-166	532.0	COG4299@1|root,COG4299@2|Bacteria,2IX5Y@203682|Planctomycetes	203682|Planctomycetes	S	COGs COG4299 conserved	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_6833018_6	1303518.CCALI_01258	2.262e-11	74.0	COG4537@1|root,COG4537@2|Bacteria	2|Bacteria	U	Required for transformation and DNA binding	comGC	GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944	-	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	M00331,M00429	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
CH3_k127_6833018_7	1123508.JH636446_gene6227	6.337e-06	57.0	COG2165@1|root,COG2165@2|Bacteria,2J1RN@203682|Planctomycetes	203682|Planctomycetes	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CH3_k127_6833018_8	1121946.AUAX01000016_gene4757	0.0001707	53.0	COG2755@1|root,COG3266@1|root,COG2755@2|Bacteria,COG3266@2|Bacteria,2I2V4@201174|Actinobacteria,4D9Z9@85008|Micromonosporales	201174|Actinobacteria	E	Parallel beta-helix repeats	pelX	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CBM_2,CBM_35,CBM_6
CH3_k127_6833018_5	1110502.TMO_0647	3.855e-33	138.0	COG1309@1|root,COG1309@2|Bacteria,1RDIM@1224|Proteobacteria,2VEVK@28211|Alphaproteobacteria,2JYN8@204441|Rhodospirillales	204441|Rhodospirillales	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CH3_k127_6833018_3	1250232.JQNJ01000001_gene1869	2.37e-105	359.0	COG4733@1|root,COG4733@2|Bacteria,4PNY1@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF2961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
CH3_k127_6833018_4	1123242.JH636434_gene3426	3.655e-50	184.0	COG1506@1|root,COG1506@2|Bacteria,2IXED@203682|Planctomycetes	203682|Planctomycetes	E	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
CH3_k127_683460_2	886293.Sinac_4026	3.902e-58	208.0	COG1595@1|root,COG1595@2|Bacteria,2IZ8A@203682|Planctomycetes	203682|Planctomycetes	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
CH3_k127_683460_0	366602.Caul_1283	4.653e-119	391.0	COG2730@1|root,COG2730@2|Bacteria,1N2XP@1224|Proteobacteria,2TSHY@28211|Alphaproteobacteria,2KIB4@204458|Caulobacterales	204458|Caulobacterales	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase
CH3_k127_683460_1	497964.CfE428DRAFT_4033	4.768e-106	349.0	COG0730@1|root,COG0730@2|Bacteria,46VD4@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Sulfite exporter TauE/SafE	-	-	-	-	-	-	-	-	-	-	-	-	TauE
CH3_k127_6849654_0	497964.CfE428DRAFT_3817	3.412e-122	398.0	COG1690@1|root,COG1690@2|Bacteria,46SU0@74201|Verrucomicrobia	74201|Verrucomicrobia	S	tRNA-splicing ligase RtcB	-	-	-	-	-	-	-	-	-	-	-	-	RtcB
CH3_k127_6871630_0	886293.Sinac_3465	2.284e-169	545.0	COG3356@1|root,COG3356@2|Bacteria,2IXDY@203682|Planctomycetes	203682|Planctomycetes	G	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
CH3_k127_6871630_2	247490.KSU1_C1131	8.832e-58	207.0	COG1881@1|root,COG1881@2|Bacteria,2J1MM@203682|Planctomycetes	203682|Planctomycetes	G	Phosphatidylethanolamine-binding protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP,YHYH
CH3_k127_6871630_1	1185876.BN8_01260	3.678e-113	369.0	COG2730@1|root,COG2730@2|Bacteria,4NGAC@976|Bacteroidetes,47MSS@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
CH3_k127_6932940_1	1231392.OCGS_0957	9.482e-37	143.0	COG0500@1|root,COG2226@2|Bacteria,1R439@1224|Proteobacteria,2U0N2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CH3_k127_6932940_0	319003.Bra1253DRAFT_01013	7.256e-149	483.0	COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,2TRET@28211|Alphaproteobacteria,3JQXY@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate	-	-	-	ko:K11103	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.23.1.3,2.A.23.1.6,2.A.23.1.7	-	-	SDF
CH3_k127_6932940_2	765910.MARPU_05370	4.857e-35	136.0	298PG@1|root,2ZVTY@2|Bacteria,1RIKV@1224|Proteobacteria,1SQW0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_6946581_1	497964.CfE428DRAFT_0200	5.156e-153	491.0	COG2309@1|root,COG2309@2|Bacteria,46SAI@74201|Verrucomicrobia	74201|Verrucomicrobia	E	PFAM peptidase M29 aminopeptidase II	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
CH3_k127_6946581_2	497964.CfE428DRAFT_1407	2.21e-49	188.0	COG0582@1|root,COG0582@2|Bacteria,46W0S@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
CH3_k127_6946581_6	794903.OPIT5_01350	5.909e-23	100.0	COG0582@1|root,COG0582@2|Bacteria,46W0S@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
CH3_k127_6946581_5	1385935.N836_35430	7.44e-31	127.0	2EPF5@1|root,33H1T@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_6946581_7	749414.SBI_05800	2.435e-05	51.0	COG1484@1|root,COG1484@2|Bacteria,2GNJG@201174|Actinobacteria	201174|Actinobacteria	L	DNA replication protein	-	-	-	ko:K02315,ko:K11144	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
CH3_k127_6946581_4	880072.Desac_0910	5.02e-31	128.0	COG0286@1|root,COG0286@2|Bacteria,1MW3A@1224|Proteobacteria	1224|Proteobacteria	V	type I restriction-modification system	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HTH_31,HsdM_N,N6_Mtase
CH3_k127_6946581_3	1192034.CAP_5127	3.658e-33	146.0	COG5337@1|root,COG5337@2|Bacteria,1QCJ4@1224|Proteobacteria,4341P@68525|delta/epsilon subdivisions,2X4PD@28221|Deltaproteobacteria,2YZCK@29|Myxococcales	28221|Deltaproteobacteria	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,Lectin_C
CH3_k127_6946581_0	661478.OP10G_0514	4.616e-232	749.0	COG3391@1|root,COG3511@1|root,COG3391@2|Bacteria,COG3511@2|Bacteria	2|Bacteria	M	phospholipase C	-	-	-	-	-	-	-	-	-	-	-	-	DUF1735,F5_F8_type_C,Lactonase,Phosphoesterase
CH3_k127_6954813_18	794903.OPIT5_10550	6.675e-15	85.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
CH3_k127_6954813_2	886293.Sinac_6489	1.493e-165	560.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
CH3_k127_6954813_12	1123242.JH636435_gene2613	1.473e-53	199.0	COG1595@1|root,COG1595@2|Bacteria,2IZZP@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
CH3_k127_6954813_13	344747.PM8797T_26205	1.254e-51	206.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	1.1.2.6	ko:K05889	-	-	R03136	-	ko00000,ko01000	-	-	-	DUF1863,PQQ,PQQ_2,PQQ_3
CH3_k127_6954813_3	344747.PM8797T_02169	1.231e-146	491.0	COG1409@1|root,COG1520@1|root,COG1409@2|Bacteria,COG1520@2|Bacteria,2IXB6@203682|Planctomycetes	203682|Planctomycetes	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,Metallophos,Methyltransf_25,PQQ_2
CH3_k127_6954813_17	794903.OPIT5_10630	6.324e-17	96.0	COG2133@1|root,COG3266@1|root,COG5184@1|root,COG2133@2|Bacteria,COG3266@2|Bacteria,COG5184@2|Bacteria,46Z90@74201|Verrucomicrobia,3K9IV@414999|Opitutae	414999|Opitutae	M	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	PA14
CH3_k127_6954813_19	345341.KUTG_02670	3.888e-06	61.0	COG1404@1|root,COG3055@1|root,COG1404@2|Bacteria,COG3055@2|Bacteria,2ICH5@201174|Actinobacteria,4E6DX@85010|Pseudonocardiales	201174|Actinobacteria	O	Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_6
CH3_k127_6954813_0	344747.PM8797T_32040	1.386e-216	710.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Malectin,PQQ_2,PQQ_3
CH3_k127_6954813_15	504472.Slin_2680	2.705e-35	147.0	COG2133@1|root,COG3291@1|root,COG4625@1|root,COG2133@2|Bacteria,COG3291@2|Bacteria,COG4625@2|Bacteria,4NJDV@976|Bacteroidetes,47NUN@768503|Cytophagia	976|Bacteroidetes	E	PFAM Di-glucose binding within endoplasmic reticulum	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Malectin,NPCBM,PA14,RicinB_lectin_2
CH3_k127_6954813_11	344747.PM8797T_31653	2.894e-58	219.0	2F8GG@1|root,340VA@2|Bacteria,2J3K0@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_6954813_5	344747.PM8797T_31648	3.479e-109	371.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	tagS	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CH3_k127_6954813_9	344747.PM8797T_31643	6.066e-75	259.0	COG1136@1|root,COG1136@2|Bacteria	2|Bacteria	V	lipoprotein transporter activity	-	-	-	ko:K02003,ko:K05685,ko:K09810	ko02010,map02010	M00255,M00258,M00709	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.122.1,3.A.1.122.12,3.A.1.125	-	-	ABC_tran
CH3_k127_6954813_4	344747.PM8797T_31638	3.242e-143	471.0	COG0725@1|root,COG0725@2|Bacteria,2J08C@203682|Planctomycetes	203682|Planctomycetes	P	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_11
CH3_k127_6954813_7	344747.PM8797T_31633	2.475e-95	323.0	COG0555@1|root,COG0555@2|Bacteria,2IYJ3@203682|Planctomycetes	203682|Planctomycetes	O	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
CH3_k127_6954813_10	344747.PM8797T_31628	3.187e-71	247.0	COG3842@1|root,COG3842@2|Bacteria,2IZ85@203682|Planctomycetes	203682|Planctomycetes	E	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
CH3_k127_6954813_6	344747.PM8797T_31618	4.892e-104	352.0	COG0476@1|root,COG0476@2|Bacteria,2IY5K@203682|Planctomycetes	203682|Planctomycetes	H	ThiF family	-	-	-	-	-	-	-	-	-	-	-	-	ThiF
CH3_k127_6954813_1	1396141.BATP01000060_gene4727	1.201e-211	702.0	COG0457@1|root,COG3712@1|root,COG0457@2|Bacteria,COG3712@2|Bacteria	2|Bacteria	PT	iron ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	FecR,TPR_16,TPR_19,TPR_8,TonB_dep_Rec
CH3_k127_6954813_16	251221.35213566	9.091e-23	114.0	COG1404@1|root,COG5549@1|root,COG1404@2|Bacteria,COG5549@2|Bacteria,1G72X@1117|Cyanobacteria	1117|Cyanobacteria	O	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_6954813_8	378806.STAUR_6001	9.206e-88	308.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,4393J@68525|delta/epsilon subdivisions,2X49H@28221|Deltaproteobacteria,2YYJE@29|Myxococcales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
CH3_k127_6954813_14	452637.Oter_3071	5.067e-45	170.0	COG0784@1|root,COG3829@1|root,COG3852@1|root,COG0784@2|Bacteria,COG3829@2|Bacteria,COG3852@2|Bacteria,46UP4@74201|Verrucomicrobia,3KA37@414999|Opitutae	414999|Opitutae	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
CH3_k127_6955762_5	1227360.C176_13277	8.829e-76	283.0	COG2366@1|root,COG2366@2|Bacteria,1UFHA@1239|Firmicutes,4HACM@91061|Bacilli,26EP7@186818|Planococcaceae	91061|Bacilli	S	Penicillin acylase	acyII	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
CH3_k127_6955762_3	1123508.JH636449_gene7418	1.929e-145	477.0	COG1680@1|root,COG1680@2|Bacteria,2J0ZW@203682|Planctomycetes	203682|Planctomycetes	V	Beta-lactamase class C	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CH3_k127_6955762_0	886293.Sinac_7111	5.4e-323	1023.0	COG2010@1|root,COG2010@2|Bacteria,2IYDW@203682|Planctomycetes	203682|Planctomycetes	C	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PSCyt1,PSCyt2,PSD1
CH3_k127_6955762_1	1123242.JH636434_gene4686	2.4e-223	701.0	COG3119@1|root,COG3119@2|Bacteria,2IX1H@203682|Planctomycetes	203682|Planctomycetes	P	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CH3_k127_6955762_10	1288963.ADIS_1441	5.395e-25	112.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG2755@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,COG2755@2|Bacteria,4NEQA@976|Bacteroidetes,47MTS@768503|Cytophagia	976|Bacteroidetes	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3,HEAT_2,Lipase_GDSL_2
CH3_k127_6955762_9	1123508.JH636443_gene5054	7.764e-36	151.0	COG2993@1|root,COG2993@2|Bacteria,2IZNM@203682|Planctomycetes	203682|Planctomycetes	C	COGs COG2993 Cbb3-type cytochrome oxidase cytochrome c subunit	-	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixO
CH3_k127_6955762_4	794903.OPIT5_22615	1.694e-90	316.0	COG3278@1|root,COG3278@2|Bacteria,46T64@74201|Verrucomicrobia,3K7FT@414999|Opitutae	414999|Opitutae	C	Cytochrome C and Quinol oxidase polypeptide I	-	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
CH3_k127_6955762_11	452637.Oter_3929	0.000182	49.0	2B8Q9@1|root,321ZW@2|Bacteria,46XX6@74201|Verrucomicrobia,3K8IF@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_6955762_6	452637.Oter_3930	6.78e-69	250.0	COG4531@1|root,COG4531@2|Bacteria,46SME@74201|Verrucomicrobia,3K79U@414999|Opitutae	414999|Opitutae	P	ABC-type Zn2 transport system, periplasmic component surface adhesin	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_6955762_8	794903.OPIT5_22595	6.059e-42	163.0	COG2010@1|root,COG2010@2|Bacteria,46SV4@74201|Verrucomicrobia,3K7Z7@414999|Opitutae	414999|Opitutae	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CH3_k127_6955762_7	794903.OPIT5_22590	2.684e-60	214.0	COG2010@1|root,COG2010@2|Bacteria,46V1P@74201|Verrucomicrobia,3K7WS@414999|Opitutae	414999|Opitutae	C	Protein of unknown function (DUF3341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
CH3_k127_6955762_2	794903.OPIT5_22585	2.639e-197	621.0	COG5557@1|root,COG5557@2|Bacteria,46S9S@74201|Verrucomicrobia,3K751@414999|Opitutae	414999|Opitutae	C	Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
CH3_k127_6968601_4	756272.Plabr_3359	1.147e-81	276.0	COG3828@1|root,COG3828@2|Bacteria,2IY8Q@203682|Planctomycetes	203682|Planctomycetes	S	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
CH3_k127_6968601_12	314230.DSM3645_21462	9.881e-07	50.0	COG3828@1|root,COG3828@2|Bacteria,2IY8Q@203682|Planctomycetes	203682|Planctomycetes	S	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
CH3_k127_6968601_11	1396141.BATP01000016_gene2783	3.754e-12	77.0	2BN1X@1|root,32GN2@2|Bacteria,46XN3@74201|Verrucomicrobia,2IW8A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_6968601_0	497964.CfE428DRAFT_1603	5.618e-179	572.0	COG0673@1|root,COG0673@2|Bacteria,46TYR@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CH3_k127_6968601_7	323261.Noc_1412	5.132e-58	208.0	28NM7@1|root,2ZBMT@2|Bacteria,1R9Y9@1224|Proteobacteria,1S227@1236|Gammaproteobacteria,1X0Q2@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF2959)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2959
CH3_k127_6968601_5	530564.Psta_1556	3.839e-60	220.0	29525@1|root,2ZSEY@2|Bacteria,2IZ8U@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_6968601_6	497964.CfE428DRAFT_3900	4.251e-58	211.0	2AU2S@1|root,31JP5@2|Bacteria,46VDJ@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CH3_k127_6968601_10	635013.TherJR_1860	1.832e-15	81.0	COG1872@1|root,COG1872@2|Bacteria,1VFSH@1239|Firmicutes,24T87@186801|Clostridia,262RJ@186807|Peptococcaceae	186801|Clostridia	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
CH3_k127_6968601_2	498848.TaqDRAFT_4878	7.375e-116	398.0	COG4447@1|root,COG4447@2|Bacteria,1WJIB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_6968601_1	452637.Oter_1389	5.163e-166	550.0	COG0515@1|root,COG0515@2|Bacteria,46VB0@74201|Verrucomicrobia,3K8AK@414999|Opitutae	414999|Opitutae	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CH3_k127_6968601_8	452637.Oter_2422	1.725e-56	204.0	COG1595@1|root,COG1595@2|Bacteria,46VAN@74201|Verrucomicrobia	74201|Verrucomicrobia	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
CH3_k127_6968601_3	452637.Oter_0016	3.658e-108	369.0	COG0530@1|root,COG0530@2|Bacteria,46Y13@74201|Verrucomicrobia,3K8RV@414999|Opitutae	414999|Opitutae	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
CH3_k127_6968601_9	583355.Caka_0236	1.457e-25	111.0	2A5NK@1|root,30UDC@2|Bacteria,46YMP@74201|Verrucomicrobia,3K9UM@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_7007169_0	240016.ABIZ01000001_gene2819	1.766e-183	591.0	COG5421@1|root,COG5421@2|Bacteria,46U8B@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
CH3_k127_7007169_1	671143.DAMO_1527	4.338e-108	358.0	COG0530@1|root,COG0530@2|Bacteria,2NPPD@2323|unclassified Bacteria	2|Bacteria	P	Sodium/calcium exchanger protein	yrbG	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
CH3_k127_7007169_3	497964.CfE428DRAFT_2480	2.9e-34	138.0	2AEIE@1|root,314DU@2|Bacteria,46WQ3@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_7007169_2	497964.CfE428DRAFT_3135	2.72e-41	155.0	COG0013@1|root,COG0013@2|Bacteria,46SAY@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
CH3_k127_702986_0	240016.ABIZ01000001_gene2673	2.082e-167	542.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,46U7Q@74201|Verrucomicrobia,2ITXJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	NAD synthase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase,NAD_synthase
CH3_k127_702986_1	525897.Dbac_3292	3.275e-46	174.0	COG0463@1|root,COG0463@2|Bacteria,1QV9Z@1224|Proteobacteria	1224|Proteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CH3_k127_7035032_1	247490.KSU1_B0100	5.504e-150	484.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4372
CH3_k127_7035032_8	32057.KB217478_gene6407	0.0004207	45.0	2E953@1|root,333DW@2|Bacteria,1G8VT@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_7035032_7	313606.M23134_07014	0.0003703	43.0	COG4974@1|root,COG4974@2|Bacteria,4NSQX@976|Bacteroidetes,47RQT@768503|Cytophagia	976|Bacteroidetes	L	Plasmid pRiA4b ORF-3-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3
CH3_k127_7035032_0	1183438.GKIL_4380	4.404e-158	559.0	COG1404@1|root,COG1404@2|Bacteria,1G8UV@1117|Cyanobacteria	1117|Cyanobacteria	O	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8,VCBS
CH3_k127_7035032_5	261292.Nit79A3_2710	3.772e-26	128.0	COG3468@1|root,COG3468@2|Bacteria,1QUZ3@1224|Proteobacteria	1224|Proteobacteria	MU	heme binding	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,TIG
CH3_k127_7035032_3	251221.35213566	1.19e-71	278.0	COG1404@1|root,COG5549@1|root,COG1404@2|Bacteria,COG5549@2|Bacteria,1G72X@1117|Cyanobacteria	1117|Cyanobacteria	O	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_7035032_6	682795.AciX8_3725	6.249e-10	74.0	COG3250@1|root,COG3250@2|Bacteria,3Y3GV@57723|Acidobacteria,2JHVR@204432|Acidobacteriia	204432|Acidobacteriia	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4982,F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_64,Ig_3
CH3_k127_7035032_2	1353529.M899_0311	2.215e-124	404.0	COG1951@1|root,COG1951@2|Bacteria,1MUV9@1224|Proteobacteria,42MC7@68525|delta/epsilon subdivisions,2WKIV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	hydro-lyase, Fe-S type, tartrate fumarate subfamily, alpha subunit	fumA	-	4.2.1.2	ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
CH3_k127_7035032_4	452637.Oter_0854	3.545e-35	153.0	COG3291@1|root,COG3291@2|Bacteria,46Z7J@74201|Verrucomicrobia,3KA3F@414999|Opitutae	2|Bacteria	S	SMART Immunoglobulin C2 type	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,He_PIG,Ig_3,VCBS
CH3_k127_7079197_33	398767.Glov_3575	8.235e-05	46.0	COG1300@1|root,COG1300@2|Bacteria,1Q1GN@1224|Proteobacteria,42UUJ@68525|delta/epsilon subdivisions,2WQQ0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Stage II sporulation protein M	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIM
CH3_k127_7079197_2	497964.CfE428DRAFT_2659	1.223e-161	522.0	COG1721@1|root,COG1721@2|Bacteria,46SN6@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CH3_k127_7079197_3	497964.CfE428DRAFT_2658	4.089e-148	477.0	COG0714@1|root,COG0714@2|Bacteria,46S8X@74201|Verrucomicrobia	74201|Verrucomicrobia	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CH3_k127_7079197_13	497964.CfE428DRAFT_2657	1.845e-73	269.0	COG5414@1|root,COG5414@2|Bacteria,46VD3@74201|Verrucomicrobia	74201|Verrucomicrobia	K	histone acetyltransferase binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_7079197_6	497964.CfE428DRAFT_2656	1.888e-127	427.0	2EQIM@1|root,2ZBQ8@2|Bacteria,46TFZ@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF4129)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
CH3_k127_7079197_21	497964.CfE428DRAFT_2655	1.655e-26	111.0	2ES4R@1|root,33JPJ@2|Bacteria,46T9B@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_7079197_27	398767.Glov_3581	2.332e-14	83.0	2B0DH@1|root,31SQS@2|Bacteria,1P6ED@1224|Proteobacteria,4328H@68525|delta/epsilon subdivisions,2WXMR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_7079197_20	439235.Dalk_0968	4.539e-31	129.0	2ECUE@1|root,336RY@2|Bacteria,1P3V9@1224|Proteobacteria,431ZA@68525|delta/epsilon subdivisions,2WX45@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_7079197_24	583355.Caka_1232	1.715e-22	109.0	COG5523@1|root,COG5523@2|Bacteria,46ZK6@74201|Verrucomicrobia,3KA3R@414999|Opitutae	2|Bacteria	S	Domain of unknown function (DUF4339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF975
CH3_k127_7079197_30	771875.Ferpe_1246	9.727e-10	62.0	COG0230@1|root,COG0230@2|Bacteria,2GDMP@200918|Thermotogae	200918|Thermotogae	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
CH3_k127_7079197_28	756499.Desde_4254	1.815e-11	70.0	COG0594@1|root,COG0594@2|Bacteria,1TV50@1239|Firmicutes,259HJ@186801|Clostridia,2633N@186807|Peptococcaceae	186801|Clostridia	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
CH3_k127_7079197_23	1244869.H261_16660	3.446e-23	104.0	COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,2UFKH@28211|Alphaproteobacteria,2JTTP@204441|Rhodospirillales	204441|Rhodospirillales	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
CH3_k127_7079197_8	583355.Caka_2475	2.856e-87	311.0	COG0706@1|root,COG0706@2|Bacteria,46SHI@74201|Verrucomicrobia,3K72P@414999|Opitutae	414999|Opitutae	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
CH3_k127_7079197_22	497964.CfE428DRAFT_1418	1.942e-24	108.0	COG1847@1|root,COG1847@2|Bacteria,46VYD@74201|Verrucomicrobia	74201|Verrucomicrobia	S	R3H domain	-	-	-	-	-	-	-	-	-	-	-	-	R3H
CH3_k127_7079197_18	497964.CfE428DRAFT_4578	1.549e-37	146.0	COG1762@1|root,COG1762@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	ptsN3	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770,ko:K02806	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2
CH3_k127_7079197_0	497964.CfE428DRAFT_4579	1.09e-218	693.0	COG0018@1|root,COG0018@2|Bacteria,46SH6@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Arginyl tRNA synthetase N terminal dom	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
CH3_k127_7079197_4	583355.Caka_0776	3.68e-143	460.0	COG0714@1|root,COG0714@2|Bacteria,46SC8@74201|Verrucomicrobia,3K7W0@414999|Opitutae	414999|Opitutae	S	PFAM ATPase associated with various cellular activities AAA_3	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CH3_k127_7079197_26	240015.ACP_0051	7.958e-15	78.0	COG3668@1|root,COG3668@2|Bacteria	2|Bacteria	D	Plasmid stabilization system	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
CH3_k127_7079197_9	1167006.UWK_00745	2.667e-83	287.0	COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria,42PJB@68525|delta/epsilon subdivisions,2WK1X@28221|Deltaproteobacteria,2MJBE@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CH3_k127_7079197_11	583355.Caka_0779	4.724e-79	278.0	COG2304@1|root,COG2304@2|Bacteria,46SKE@74201|Verrucomicrobia,3K7H6@414999|Opitutae	414999|Opitutae	S	PFAM von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
CH3_k127_7079197_14	1167006.UWK_00742	2.24e-71	254.0	COG0457@1|root,COG2304@1|root,COG5414@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,COG5414@2|Bacteria,1MW51@1224|Proteobacteria,42M45@68525|delta/epsilon subdivisions,2WM19@28221|Deltaproteobacteria,2MHT6@213118|Desulfobacterales	28221|Deltaproteobacteria	K	PFAM von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	TPR_1,TPR_16,TPR_2,VWA,VWA_2
CH3_k127_7079197_31	1506583.JQJY01000007_gene4146	1.361e-08	68.0	COG0457@1|root,COG0457@2|Bacteria,4NERG@976|Bacteroidetes,1HYP9@117743|Flavobacteriia,2NU2K@237|Flavobacterium	976|Bacteroidetes	S	BatD protein	batD	-	-	-	-	-	-	-	-	-	-	-	BatD,TPR_2
CH3_k127_7079197_29	742817.HMPREF9449_01242	9.317e-11	73.0	COG0457@1|root,COG0457@2|Bacteria,4NF5V@976|Bacteroidetes,2FP54@200643|Bacteroidia,22XN2@171551|Porphyromonadaceae	976|Bacteroidetes	T	Tetratricopeptide repeat	batE	-	-	-	-	-	-	-	-	-	-	-	SH3_3,SH3_4,TPR_1,TPR_11,TPR_16,TPR_2
CH3_k127_7079197_15	234267.Acid_1327	1.184e-69	261.0	COG0318@1|root,COG0318@2|Bacteria,3Y65U@57723|Acidobacteria	57723|Acidobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
CH3_k127_7079197_10	234267.Acid_1327	7.229e-80	285.0	COG0318@1|root,COG0318@2|Bacteria,3Y65U@57723|Acidobacteria	57723|Acidobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
CH3_k127_7079197_17	926550.CLDAP_17040	1.259e-55	211.0	COG5276@1|root,COG5276@2|Bacteria,2G8F2@200795|Chloroflexi	200795|Chloroflexi	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
CH3_k127_7079197_25	485917.Phep_2066	4.796e-20	103.0	COG0457@1|root,COG0823@1|root,COG2885@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1IPCG@117747|Sphingobacteriia	976|Bacteroidetes	MU	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,TPR_16,TPR_2,TPR_8
CH3_k127_7079197_12	234267.Acid_0687	2.099e-78	285.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,3Y6TZ@57723|Acidobacteria	2|Bacteria	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2
CH3_k127_7079197_7	1408433.JHXV01000001_gene670	5.03e-97	340.0	COG1520@1|root,COG3291@1|root,COG5384@1|root,COG1520@2|Bacteria,COG3291@2|Bacteria,COG5384@2|Bacteria,4PKTY@976|Bacteroidetes,1IE9N@117743|Flavobacteriia,2PB1T@246874|Cryomorphaceae	976|Bacteroidetes	J	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	PKD,UnbV_ASPIC,VCBS
CH3_k127_7079197_19	247490.KSU1_C0483	5.309e-35	144.0	28WIA@1|root,2ZII9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_7079197_1	886293.Sinac_6489	1.501e-176	595.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
CH3_k127_7079197_16	497964.CfE428DRAFT_4864	6.578e-64	227.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_7079197_5	522306.CAP2UW1_0198	6.022e-131	421.0	COG0560@1|root,COG0560@2|Bacteria,1MW38@1224|Proteobacteria,2VN83@28216|Betaproteobacteria	28216|Betaproteobacteria	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
CH3_k127_7083049_1	497964.CfE428DRAFT_0797	1.775e-201	652.0	COG0060@1|root,COG0060@2|Bacteria,46SEC@74201|Verrucomicrobia	74201|Verrucomicrobia	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
CH3_k127_7083049_2	497964.CfE428DRAFT_1506	1.42e-147	478.0	COG0766@1|root,COG0766@2|Bacteria,46S6Q@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
CH3_k127_7083049_3	1125863.JAFN01000001_gene1724	1.516e-63	228.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,42PKA@68525|delta/epsilon subdivisions,2WNH0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
CH3_k127_7083049_5	1038869.AXAN01000002_gene225	4.06e-30	132.0	COG0628@1|root,COG0628@2|Bacteria,1MW34@1224|Proteobacteria,2VIKI@28216|Betaproteobacteria,1K0I9@119060|Burkholderiaceae	28216|Betaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
CH3_k127_7083049_0	240016.ABIZ01000001_gene1604	2.129e-232	733.0	COG0423@1|root,COG0423@2|Bacteria,46TEV@74201|Verrucomicrobia,2ITMG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Anticodon binding domain	-	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
CH3_k127_7083049_4	759914.BP951000_2310	7.26e-31	141.0	COG4485@1|root,COG5617@1|root,COG4485@2|Bacteria,COG5617@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
CH3_k127_7099496_0	240016.ABIZ01000001_gene2256	0.0	1240.0	COG1413@1|root,COG2133@1|root,COG3828@1|root,COG1413@2|Bacteria,COG2133@2|Bacteria,COG3828@2|Bacteria,46XAM@74201|Verrucomicrobia,2IV7A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CG	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,ThuA
CH3_k127_7099496_1	497964.CfE428DRAFT_3584	7.654e-174	554.0	COG5441@1|root,COG5441@2|Bacteria,46U7U@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Uncharacterised protein family (UPF0261)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0261
CH3_k127_7099496_3	411473.RUMCAL_02004	2.069e-75	272.0	COG5492@1|root,COG5492@2|Bacteria,1TS8J@1239|Firmicutes,24A7I@186801|Clostridia,3WGX5@541000|Ruminococcaceae	186801|Clostridia	N	dockerin type I repeat-containing domain protein	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5
CH3_k127_7099496_2	768706.Desor_3179	9.734e-156	523.0	COG5492@1|root,COG5492@2|Bacteria,1TS8J@1239|Firmicutes,24A7I@186801|Clostridia,262NZ@186807|Peptococcaceae	186801|Clostridia	N	Leucine rich repeats (6 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,LRR_5
CH3_k127_7115999_2	443143.GM18_2869	5.066e-31	125.0	COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria,42M86@68525|delta/epsilon subdivisions,2WIT1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Subunit R is required for both nuclease and ATPase activities, but not for modification	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
CH3_k127_7115999_0	1303518.CCALI_02122	1.549e-244	793.0	2C33Y@1|root,33VR5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_7115999_1	1123242.JH636434_gene4801	3.363e-35	135.0	COG1028@1|root,COG1028@2|Bacteria	1123242.JH636434_gene4801|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_7131738_2	702438.HMPREF9431_00108	1.445e-21	101.0	COG1569@1|root,COG1569@2|Bacteria,4NSS3@976|Bacteroidetes,2FTP8@200643|Bacteroidia	976|Bacteroidetes	S	toxin-antitoxin system toxin component, PIN family	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
CH3_k127_7131738_0	497964.CfE428DRAFT_1743	7.77e-268	838.0	COG1166@1|root,COG1166@2|Bacteria,46S4T@74201|Verrucomicrobia	74201|Verrucomicrobia	E	arginine decarboxylase	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N
CH3_k127_7131738_1	497964.CfE428DRAFT_0749	1.439e-87	297.0	COG0327@1|root,COG0327@2|Bacteria	2|Bacteria	L	Belongs to the GTP cyclohydrolase I type 2 NIF3 family	ybgI	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0050896	3.5.4.16	ko:K22391	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	NIF3
CH3_k127_7131738_4	1403819.BATR01000133_gene4737	0.0002693	50.0	2FCQS@1|root,344TZ@2|Bacteria,46W38@74201|Verrucomicrobia,2IUKT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_7131738_3	439235.Dalk_3377	8.308e-17	82.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,42RGS@68525|delta/epsilon subdivisions,2WNJR@28221|Deltaproteobacteria,2MJU3@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
CH3_k127_7132080_6	861299.J421_1306	2.524e-12	70.0	COG0296@1|root,COG0296@2|Bacteria,1ZU2E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Glycogen recognition site of AMP-activated protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM
CH3_k127_7132080_1	530564.Psta_1651	6.707e-76	269.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	AXE1,BAAT_C,Peptidase_S9
CH3_k127_7132080_2	323848.Nmul_A2162	7.533e-48	177.0	COG1539@1|root,COG1539@2|Bacteria,1QVAP@1224|Proteobacteria,2WHHJ@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Putative molybdenum carrier	-	-	-	-	-	-	-	-	-	-	-	-	MoCo_carrier
CH3_k127_7132080_3	1283300.ATXB01000001_gene2112	1.742e-46	170.0	COG3411@1|root,COG3411@2|Bacteria,1MZR4@1224|Proteobacteria,1T12G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_7132080_4	643562.Daes_0072	1.342e-29	123.0	2DQ60@1|root,334WQ@2|Bacteria,1NADI@1224|Proteobacteria,42WP8@68525|delta/epsilon subdivisions,2WRS6@28221|Deltaproteobacteria,2MD9Z@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of Unknown function (DUF2784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2784
CH3_k127_7132080_8	391625.PPSIR1_34952	1.654e-07	61.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	ko:K21397	-	-	-	-	ko00000,ko02000	3.A.1	-	-	FHA,Trans_reg_C,Yop-YscD_cpl
CH3_k127_7132080_7	1121127.JAFA01000084_gene4611	7.869e-12	71.0	2DSZ1@1|root,33HZU@2|Bacteria,1PXZ0@1224|Proteobacteria,2WD9I@28216|Betaproteobacteria,1K9SN@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_7132080_5	858215.Thexy_1863	4.67e-22	110.0	COG5433@1|root,COG5433@2|Bacteria,1V0JK@1239|Firmicutes,249XC@186801|Clostridia,42IGR@68295|Thermoanaerobacterales	186801|Clostridia	L	PFAM Transposase, IS4-like	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
CH3_k127_713865_7	1237149.C900_02921	0.0009642	46.0	COG0304@1|root,COG0304@2|Bacteria,4NMSI@976|Bacteroidetes,47RR4@768503|Cytophagia	976|Bacteroidetes	IQ	3-oxoacyl-ACP synthase	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_713865_3	1121918.ARWE01000001_gene3128	8.476e-24	105.0	COG0236@1|root,COG0236@2|Bacteria,1N6RU@1224|Proteobacteria,42V26@68525|delta/epsilon subdivisions,2WQ0Y@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	Phosphopantetheine attachment site	acpP-1	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
CH3_k127_713865_0	575615.HMPREF0670_01520	1.851e-85	311.0	COG0304@1|root,COG0304@2|Bacteria,4NFC8@976|Bacteroidetes,2FPUI@200643|Bacteroidia	976|Bacteroidetes	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_2,Ketoacyl-synt_C,ketoacyl-synt
CH3_k127_713865_2	1347393.HG726029_gene2088	1.466e-46	180.0	COG0726@1|root,COG0726@2|Bacteria,4NM7D@976|Bacteroidetes,2FR15@200643|Bacteroidia,4AP6F@815|Bacteroidaceae	976|Bacteroidetes	G	Polysaccharide deacetylase	pgdA	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	DUF3298,Polysacc_deac_1
CH3_k127_713865_4	443143.GM18_4060	2.116e-14	82.0	COG2834@1|root,COG2834@2|Bacteria,1N3XP@1224|Proteobacteria,42TP4@68525|delta/epsilon subdivisions,2WQR3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	LolA
CH3_k127_713865_6	1232437.KL661961_gene3016	5.085e-08	64.0	COG0764@1|root,COG0764@2|Bacteria,1NNU2@1224|Proteobacteria,437EX@68525|delta/epsilon subdivisions,2X2M8@28221|Deltaproteobacteria,2MP7V@213118|Desulfobacterales	28221|Deltaproteobacteria	I	FabA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	FabA
CH3_k127_713865_1	1313421.JHBV01000138_gene1213	6.222e-76	277.0	COG3049@1|root,COG3049@2|Bacteria,4PKMY@976|Bacteroidetes,1J0M9@117747|Sphingobacteriia	976|Bacteroidetes	M	Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	AAT
CH3_k127_713865_5	671143.DAMO_1369	4.038e-10	68.0	COG0204@1|root,COG0204@2|Bacteria,2NPW3@2323|unclassified Bacteria	2|Bacteria	I	Phosphate acyltransferases	cmk	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
CH3_k127_7165677_3	471853.Bcav_3334	2.222e-21	106.0	29XIB@1|root,30J98@2|Bacteria,2H3UJ@201174|Actinobacteria	471853.Bcav_3334|-	S	Heparinase II/III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_7165677_0	344747.PM8797T_17834	3.084e-121	404.0	COG3356@1|root,COG3356@2|Bacteria,2IX5S@203682|Planctomycetes	203682|Planctomycetes	S	Neutral/alkaline non-lysosomal ceramidase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
CH3_k127_7165677_1	344747.PM8797T_30449	1.582e-47	185.0	294P7@1|root,2ZS2I@2|Bacteria,2J4KK@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_7165677_2	266117.Rxyl_1295	2.468e-37	150.0	COG1404@1|root,COG3485@1|root,COG1404@2|Bacteria,COG3485@2|Bacteria,2GJYH@201174|Actinobacteria,4CS04@84995|Rubrobacteria	84995|Rubrobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
CH3_k127_7201215_6	1123401.JHYQ01000003_gene2070	4.754e-31	143.0	COG5267@1|root,COG5267@2|Bacteria,1MWJK@1224|Proteobacteria,1RSEC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
CH3_k127_7201215_4	99598.Cal7507_0707	3.344e-36	158.0	COG4102@1|root,COG4102@2|Bacteria,1G2W5@1117|Cyanobacteria,1HM3H@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CH3_k127_7201215_7	760192.Halhy_1586	7.711e-21	104.0	COG2931@1|root,COG2931@2|Bacteria,4NKF1@976|Bacteroidetes,1IVE6@117747|Sphingobacteriia	976|Bacteroidetes	Q	A domain in the BMP inhibitor chordin and in microbial proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CHRD,SusE
CH3_k127_7201215_1	530564.Psta_1270	1.098e-88	311.0	COG1520@1|root,COG1520@2|Bacteria,2IXST@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CH3_k127_7201215_2	290397.Adeh_1286	2.07e-70	245.0	COG0454@1|root,COG0456@2|Bacteria,1RD40@1224|Proteobacteria,43EF3@68525|delta/epsilon subdivisions,2X0ID@28221|Deltaproteobacteria,2Z1N2@29|Myxococcales	28221|Deltaproteobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CH3_k127_7201215_5	1396418.BATQ01000049_gene401	2.056e-35	142.0	COG3654@1|root,COG3654@2|Bacteria	2|Bacteria	-	-	doc	-	-	ko:K07341	-	-	-	-	ko00000,ko02048	-	-	-	Fic
CH3_k127_7201215_0	929562.Emtol_1353	7.227e-159	518.0	COG3653@1|root,COG3653@2|Bacteria,4NHDD@976|Bacteroidetes,47KC3@768503|Cytophagia	976|Bacteroidetes	Q	PFAM D-aminoacylase, C-terminal region	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
CH3_k127_7201215_3	452637.Oter_0714	6.275e-59	211.0	COG1595@1|root,COG1639@1|root,COG1595@2|Bacteria,COG1639@2|Bacteria	2|Bacteria	T	HDOD domain	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	HDOD,Sigma70_r2,Sigma70_r4_2
CH3_k127_7233984_0	1303518.CCALI_02122	9.196e-221	724.0	2C33Y@1|root,33VR5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_7233984_1	768671.ThimaDRAFT_0503	2.732e-50	184.0	COG1321@1|root,COG1321@2|Bacteria,1N8WG@1224|Proteobacteria,1SQA0@1236|Gammaproteobacteria,1X16W@135613|Chromatiales	1224|Proteobacteria	K	iron dependent repressor	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_7265627_10	243233.MCA2757	2.258e-41	159.0	COG0385@1|root,COG0385@2|Bacteria	2|Bacteria	S	bile acid:sodium symporter activity	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
CH3_k127_7265627_7	1123258.AQXZ01000016_gene2259	1.094e-53	199.0	COG3675@1|root,COG3675@2|Bacteria,2HK7P@201174|Actinobacteria,4G7ZK@85025|Nocardiaceae	201174|Actinobacteria	I	Lipase (class 3)	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_3
CH3_k127_7265627_2	166318.Syn8016DRAFT_1989	9.739e-163	538.0	COG0643@1|root,COG0643@2|Bacteria,1G26V@1117|Cyanobacteria,1H46D@1129|Synechococcus	1117|Cyanobacteria	NT	Signal transducing histidine kinase, homodimeric domain	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
CH3_k127_7265627_11	931626.Awo_c04230	2.615e-40	161.0	COG0835@1|root,COG0835@2|Bacteria,1V4VQ@1239|Firmicutes,24BQT@186801|Clostridia	186801|Clostridia	NT	Chemoreceptor zinc-binding domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CZB,CheW
CH3_k127_7265627_0	880072.Desac_2375	1.289e-202	640.0	COG2114@1|root,COG5000@1|root,COG2114@2|Bacteria,COG5000@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,HAMP,HATPase_c,HD_5,HisKA,PAS,PAS_9,Response_reg,dCache_1
CH3_k127_7265627_6	880072.Desac_2374	7.011e-84	281.0	COG1719@1|root,COG1719@2|Bacteria,1RH5H@1224|Proteobacteria,42SDY@68525|delta/epsilon subdivisions,2WPEQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM 4-vinyl reductase, 4VR	-	-	-	ko:K07013	-	-	-	-	ko00000	-	-	-	V4R
CH3_k127_7265627_4	665571.STHERM_c12790	7.989e-142	465.0	COG0438@1|root,COG0438@2|Bacteria,2J6VH@203691|Spirochaetes	203691|Spirochaetes	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
CH3_k127_7265627_1	926550.CLDAP_09870	1.072e-181	586.0	COG0366@1|root,COG0366@2|Bacteria	2|Bacteria	G	hydrolase activity, hydrolyzing O-glycosyl compounds	ycjM	-	2.4.1.7	ko:K00690	ko00500,map00500	-	R00803	RC00028	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459,Malt_amylase_C
CH3_k127_7265627_8	1347392.CCEZ01000010_gene2401	8.406e-47	181.0	COG0530@1|root,COG0530@2|Bacteria,1TRX0@1239|Firmicutes,24ABZ@186801|Clostridia,36EZ7@31979|Clostridiaceae	186801|Clostridia	P	K -dependent Na Ca exchanger	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
CH3_k127_7265627_14	1499967.BAYZ01000073_gene2050	3.004e-08	65.0	COG1011@1|root,COG1011@2|Bacteria	2|Bacteria	S	phosphatase activity	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD,HAD_2,Hydrolase,Hydrolase_like
CH3_k127_7265627_12	665571.STHERM_c16620	5.125e-25	121.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	2.4.1.270	ko:K21369	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CH3_k127_7265627_5	497964.CfE428DRAFT_2620	3.736e-116	379.0	COG0330@1|root,COG0330@2|Bacteria,46VDU@74201|Verrucomicrobia	74201|Verrucomicrobia	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
CH3_k127_7265627_3	671143.DAMO_1541	2.285e-146	473.0	COG1215@1|root,COG1215@2|Bacteria,2NNSB@2323|unclassified Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	gpgS	-	2.4.1.266	ko:K13693	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	-
CH3_k127_7265627_9	452637.Oter_0434	7.092e-46	172.0	COG0835@1|root,COG0835@2|Bacteria,46VRE@74201|Verrucomicrobia,3K82Y@414999|Opitutae	414999|Opitutae	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
CH3_k127_7265627_15	757424.Hsero_3022	2.518e-05	55.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VIZN@28216|Betaproteobacteria,473DT@75682|Oxalobacteraceae	28216|Betaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	wspA	-	-	ko:K13487	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001	-	-	-	4HB_MCP_1,CHASE3,HAMP,MCPsignal
CH3_k127_7271716_6	1077974.GOEFS_062_00290	2.25e-28	119.0	COG0443@1|root,COG0443@2|Bacteria,2GJTY@201174|Actinobacteria,4GAX0@85026|Gordoniaceae	201174|Actinobacteria	O	Heat shock 70 kDa protein	dnaK	GO:0000302,GO:0000303,GO:0000305,GO:0001968,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009893,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016310,GO:0019222,GO:0019538,GO:0019899,GO:0030112,GO:0030162,GO:0030312,GO:0030313,GO:0031323,GO:0031325,GO:0031975,GO:0031982,GO:0032268,GO:0032270,GO:0033554,GO:0034599,GO:0034614,GO:0035375,GO:0036211,GO:0040007,GO:0042221,GO:0042603,GO:0043170,GO:0043226,GO:0043227,GO:0043230,GO:0043388,GO:0043412,GO:0044044,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046677,GO:0046688,GO:0046777,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051098,GO:0051099,GO:0051101,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0070613,GO:0070887,GO:0071450,GO:0071451,GO:0071704,GO:0071944,GO:0080090,GO:0097691,GO:1901564,GO:1901700,GO:1901701,GO:1903317,GO:1903319,GO:1903561,GO:2000677,GO:2000679	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
CH3_k127_7271716_5	481448.Minf_2177	1.437e-34	135.0	COG0234@1|root,COG0234@2|Bacteria,46SZ8@74201|Verrucomicrobia,37GWD@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
CH3_k127_7271716_0	452637.Oter_2054	6.108e-272	844.0	COG0459@1|root,COG0459@2|Bacteria,46S9U@74201|Verrucomicrobia,3K7T7@414999|Opitutae	414999|Opitutae	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	-	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
CH3_k127_7271716_3	497964.CfE428DRAFT_1374	7.644e-59	222.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	Phage_int_SAM_3,Phage_integrase
CH3_k127_7271716_1	1122169.AREN01000009_gene626	4.957e-64	248.0	COG4643@1|root,COG4983@1|root,COG4643@2|Bacteria,COG4983@2|Bacteria,1N636@1224|Proteobacteria,1RZVN@1236|Gammaproteobacteria,1JD83@118969|Legionellales	118969|Legionellales	S	Protein of unknown function (DUF3987)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3987
CH3_k127_7271716_2	278963.ATWD01000001_gene3347	4.029e-63	235.0	COG5434@1|root,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBM-like,F5_F8_type_C,Pectate_lyase_3
CH3_k127_7271716_4	443143.GM18_2872	4.496e-37	153.0	COG0286@1|root,COG0286@2|Bacteria,1MW3A@1224|Proteobacteria,42N9K@68525|delta/epsilon subdivisions,2WINH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	PFAM N-6 DNA methylase	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
CH3_k127_7287808_3	448385.sce0660	3.515e-83	296.0	COG1266@1|root,COG1668@1|root,COG1266@2|Bacteria,COG1668@2|Bacteria,1R3RG@1224|Proteobacteria,43B64@68525|delta/epsilon subdivisions,2X6JN@28221|Deltaproteobacteria,2YVQ4@29|Myxococcales	28221|Deltaproteobacteria	CP	sodium ABC transporter, permease	-	-	-	ko:K09696	ko02010,ko02020,map02010,map02020	M00253	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.115	-	-	ABC2_membrane_2,Abi
CH3_k127_7287808_2	1254432.SCE1572_04430	8.069e-102	338.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,43C30@68525|delta/epsilon subdivisions,2X7DN@28221|Deltaproteobacteria,2YUXV@29|Myxococcales	28221|Deltaproteobacteria	V	ABC transporter	-	-	3.6.3.7	ko:K01990,ko:K09697	ko02010,ko02020,map02010,map02020	M00253,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.115	-	-	ABC_tran
CH3_k127_7287808_0	1123242.JH636436_gene628	2.599e-167	538.0	COG1502@1|root,COG1502@2|Bacteria,2IY2H@203682|Planctomycetes	203682|Planctomycetes	I	Phospholipase_D-nuclease N-terminal	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
CH3_k127_7287808_1	1232410.KI421414_gene2911	4.502e-129	427.0	COG1109@1|root,COG1109@2|Bacteria,1QUGD@1224|Proteobacteria,43BUU@68525|delta/epsilon subdivisions,2WKYP@28221|Deltaproteobacteria,43STX@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	-	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
CH3_k127_7287808_4	1123070.KB899254_gene1243	5.967e-31	126.0	COG0838@1|root,COG0838@2|Bacteria,46T33@74201|Verrucomicrobia,2IUK0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
CH3_k127_7287808_5	497964.CfE428DRAFT_2366	1.051e-13	72.0	COG3071@1|root,COG3071@2|Bacteria,46TBM@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Protein of unknown function (DUF2905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2905
CH3_k127_7319316_3	452637.Oter_0745	3.492e-57	204.0	COG0852@1|root,COG0852@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
CH3_k127_7319316_2	452637.Oter_0744	5.931e-90	298.0	COG0377@1|root,COG0377@2|Bacteria,46YVB@74201|Verrucomicrobia,3K85T@414999|Opitutae	414999|Opitutae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
CH3_k127_7319316_4	452637.Oter_0743	9.92e-52	186.0	COG0838@1|root,COG0838@2|Bacteria,46XVA@74201|Verrucomicrobia,3K8I9@414999|Opitutae	414999|Opitutae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	-	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
CH3_k127_7319316_1	1216966.BAUC01000035_gene3110	2.998e-105	361.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,1RMY7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Glutamate synthase	gltD	GO:0003674,GO:0003824,GO:0004355,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045181,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	iEC042_1314.EC042_3503,iYL1228.KPN_03625	Fer4_20,Pyr_redox_2
CH3_k127_7319316_0	1267534.KB906754_gene3778	1.701e-127	410.0	COG0649@1|root,COG0649@2|Bacteria,3Y6MU@57723|Acidobacteria,2JKN7@204432|Acidobacteriia	204432|Acidobacteriia	C	Respiratory-chain NADH dehydrogenase, 49 Kd subunit	-	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
CH3_k127_7327393_1	411479.BACUNI_04071	3.176e-53	205.0	COG0383@1|root,COG0383@2|Bacteria,4NI6N@976|Bacteroidetes,2FQGF@200643|Bacteroidia,4ANYA@815|Bacteroidaceae	976|Bacteroidetes	G	COG COG0383 Alpha-mannosidase	-	-	-	-	-	-	-	-	-	-	-	-	CBM-like,Glyco_hydro_38,Glyco_hydro_38C
CH3_k127_7327393_4	1303518.CCALI_02173	4.753e-10	70.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
CH3_k127_7327393_3	1499967.BAYZ01000095_gene4068	8.367e-18	96.0	COG0407@1|root,COG0407@2|Bacteria,2NRD5@2323|unclassified Bacteria	2|Bacteria	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
CH3_k127_7327393_0	1267534.KB906755_gene4821	2.387e-176	576.0	COG3345@1|root,COG3345@2|Bacteria,3Y44J@57723|Acidobacteria,2JIVW@204432|Acidobacteriia	204432|Acidobacteriia	G	alpha-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_7327393_2	1122605.KB893647_gene442	2.04e-23	114.0	COG3533@1|root,COG3533@2|Bacteria,4NFW3@976|Bacteroidetes	976|Bacteroidetes	G	glycosyl hydrolase of	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
CH3_k127_7372046_1	1328313.DS2_07733	4.824e-54	192.0	COG2407@1|root,COG2407@2|Bacteria,1R5ZQ@1224|Proteobacteria,1RNGR@1236|Gammaproteobacteria,469P5@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	L-fucose isomerase, C-terminal domain	-	-	5.3.1.4	ko:K01804	ko00040,ko01100,map00040,map01100	-	R01761	RC00516	ko00000,ko00001,ko01000	-	-	-	Arabinose_Isome,Fucose_iso_C
CH3_k127_7372046_3	395961.Cyan7425_3030	1.533e-11	72.0	2E1H4@1|root,33JV3@2|Bacteria,1GGCX@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_7372046_0	997884.HMPREF1068_02702	5.638e-257	842.0	COG1262@1|root,COG1262@2|Bacteria,4NKT6@976|Bacteroidetes,2FR3S@200643|Bacteroidia,4AP3C@815|Bacteroidaceae	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,NPCBM
CH3_k127_7372046_2	904296.HMPREF9124_0631	2.486e-34	153.0	28J61@1|root,2Z91S@2|Bacteria,1UYHJ@1239|Firmicutes,24EVG@186801|Clostridia,2PS0Q@265975|Oribacterium	186801|Clostridia	S	Endo-alpha-N-acetylgalactosaminidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_101,Glyco_hydro_129
CH3_k127_7378992_2	1123242.JH636434_gene4856	2.684e-87	292.0	COG0591@1|root,COG0591@2|Bacteria,2J2KC@203682|Planctomycetes	203682|Planctomycetes	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
CH3_k127_7378992_1	716928.AJQT01000101_gene335	3.145e-91	311.0	COG3386@1|root,COG3386@2|Bacteria,1MU0C@1224|Proteobacteria,2TSXG@28211|Alphaproteobacteria,4B993@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	gluconolactonase	-	-	3.1.1.17	ko:K01053,ko:K14274	ko00030,ko00040,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00040,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02427,R02933,R03751	RC00537,RC00713,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
CH3_k127_7378992_9	1485544.JQKP01000003_gene284	3.328e-09	71.0	COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,2VI5J@28216|Betaproteobacteria,44W58@713636|Nitrosomonadales	28216|Betaproteobacteria	M	AsmA family	-	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA,AsmA_2
CH3_k127_7378992_7	478741.JAFS01000001_gene1166	1.826e-24	120.0	2DN50@1|root,32VJ4@2|Bacteria,46V62@74201|Verrucomicrobia,37FXR@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
CH3_k127_7378992_6	580331.Thit_1828	4.309e-25	120.0	COG3225@1|root,COG3225@2|Bacteria,1TT1J@1239|Firmicutes,24BC2@186801|Clostridia,42FP0@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM ABC-type uncharacterised transport system	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3,ABC_transp_aux
CH3_k127_7378992_5	237368.SCABRO_02220	1.697e-34	142.0	COG1277@1|root,COG1277@2|Bacteria,2J0HW@203682|Planctomycetes	203682|Planctomycetes	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
CH3_k127_7378992_0	247490.KSU1_C0522	1.969e-92	313.0	COG1131@1|root,COG1131@2|Bacteria,2IX20@203682|Planctomycetes	203682|Planctomycetes	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CH3_k127_7378992_4	1231241.Mc24_08639	4.941e-50	195.0	COG0265@1|root,COG0265@2|Bacteria,2GCIH@200918|Thermotogae	200918|Thermotogae	M	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
CH3_k127_7378992_3	497964.CfE428DRAFT_2487	1.442e-55	213.0	28HQ3@1|root,2Z7XW@2|Bacteria,46U81@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF2851)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2851
CH3_k127_7378992_8	102129.Lepto7375DRAFT_7777	1.878e-13	80.0	COG0457@1|root,COG0714@1|root,COG0457@2|Bacteria,COG0714@2|Bacteria,1G20P@1117|Cyanobacteria,1H8AZ@1150|Oscillatoriales	1117|Cyanobacteria	L	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_2,TPR_8
CH3_k127_7388164_0	452637.Oter_4336	1.251e-316	981.0	COG3534@1|root,COG3534@2|Bacteria,46UU3@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Alpha-L-arabinofuranosidase C-terminus	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
CH3_k127_7388164_14	1117319.PSPO_04042	7.902e-08	63.0	2BCPH@1|root,3269T@2|Bacteria,1RJN1@1224|Proteobacteria,1S744@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4824)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4824
CH3_k127_7388164_8	338963.Pcar_1339	1.108e-69	250.0	28IWG@1|root,2Z8US@2|Bacteria,1NHDW@1224|Proteobacteria,42MHT@68525|delta/epsilon subdivisions,2WMMN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Predicted membrane protein (DUF2157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2157
CH3_k127_7388164_13	1337936.IJ00_11875	1.768e-17	88.0	COG1262@1|root,COG4249@1|root,COG1262@2|Bacteria,COG4249@2|Bacteria,1GQ7T@1117|Cyanobacteria,1HJ6I@1161|Nostocales	1117|Cyanobacteria	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Peptidase_C14
CH3_k127_7388164_4	644966.Tmar_2012	1.977e-84	287.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,3WCSJ@538999|Clostridiales incertae sedis	186801|Clostridia	P	Carbohydrate ABC transporter ATP-binding protein, CUT1 family	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
CH3_k127_7388164_1	756272.Plabr_0071	4.05e-119	395.0	COG3635@1|root,COG3635@2|Bacteria,2IY5S@203682|Planctomycetes	203682|Planctomycetes	G	phosphoglycerate mutase	-	-	5.4.2.12	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,PhosphMutase
CH3_k127_7388164_5	1499967.BAYZ01000097_gene4350	4.044e-81	291.0	COG4826@1|root,COG4826@2|Bacteria,2NQVB@2323|unclassified Bacteria	2|Bacteria	O	SERine  Proteinase INhibitors	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
CH3_k127_7388164_10	1191523.MROS_1767	4.331e-60	216.0	COG3298@1|root,COG3298@2|Bacteria	2|Bacteria	L	Predicted 3'-5' exonuclease related to the exonuclease domain of PolB	wlaX	-	-	ko:K07501	-	-	-	-	ko00000	-	-	-	DNA_pol_B_exo2
CH3_k127_7388164_15	596328.HMPREF0578_1655	4.647e-05	53.0	COG0775@1|root,COG0775@2|Bacteria,2I8GZ@201174|Actinobacteria,4D3DV@85005|Actinomycetales	201174|Actinobacteria	E	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively	mtnN	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
CH3_k127_7388164_9	497964.CfE428DRAFT_2670	8.939e-66	234.0	COG1562@1|root,COG1562@2|Bacteria,46TVP@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Squalene/phytoene synthase	-	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	Amino_oxidase,SQS_PSY
CH3_k127_7388164_2	880072.Desac_0330	2.947e-113	384.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2MR37@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CH3_k127_7388164_12	269799.Gmet_2562	8.551e-30	136.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,42MC9@68525|delta/epsilon subdivisions,2WIYS@28221|Deltaproteobacteria,43T97@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Nitrogen fixation master sensor histidine kinase, PAS domain-containing	gnfL	-	2.7.13.3	ko:K02668,ko:K07708,ko:K07709	ko02020,map02020	M00497,M00499,M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_8
CH3_k127_7388164_7	240016.ABIZ01000001_gene2279	7.766e-70	241.0	COG0452@1|root,COG0452@2|Bacteria,46SPU@74201|Verrucomicrobia,2IUB8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Flavoprotein	-	-	4.1.1.36	ko:K01598	ko00770,ko01100,map00770,map01100	M00120	R03269	RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
CH3_k127_7388164_11	583355.Caka_2132	1.881e-53	194.0	COG0194@1|root,COG0194@2|Bacteria,46SQG@74201|Verrucomicrobia,3K812@414999|Opitutae	414999|Opitutae	F	Guanylate kinase	-	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
CH3_k127_7388164_3	497964.CfE428DRAFT_4161	1.473e-86	295.0	COG1561@1|root,COG1561@2|Bacteria,46TP9@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF1732)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
CH3_k127_7388164_6	382464.ABSI01000011_gene2998	3.773e-75	258.0	COG0385@1|root,COG0385@2|Bacteria,46YXM@74201|Verrucomicrobia,2IU81@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	SBF-like CPA transporter family (DUF4137)	-	-	-	-	-	-	-	-	-	-	-	-	SBF
CH3_k127_7394549_0	760568.Desku_2930	2.106e-141	458.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,248JC@186801|Clostridia,260H6@186807|Peptococcaceae	186801|Clostridia	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
CH3_k127_7394549_1	1226325.HMPREF1548_02230	7.24e-137	462.0	COG3525@1|root,COG3525@2|Bacteria	2|Bacteria	G	beta-N-acetylhexosaminidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4838,F5_F8_type_C,Glyco_hydro_67N
CH3_k127_7394549_3	497964.CfE428DRAFT_4864	1.035e-62	224.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_7394549_2	886293.Sinac_6489	5.211e-84	287.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
CH3_k127_7429295_1	497964.CfE428DRAFT_1521	1.591e-65	229.0	COG0461@1|root,COG0461@2|Bacteria,46SZV@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
CH3_k127_7429295_0	497964.CfE428DRAFT_5188	1.462e-282	875.0	COG0443@1|root,COG0443@2|Bacteria,46SDM@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
CH3_k127_7449432_2	452637.Oter_1829	3.683e-64	228.0	COG0577@1|root,COG0577@2|Bacteria,46UIW@74201|Verrucomicrobia	74201|Verrucomicrobia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
CH3_k127_7449432_0	251221.35211765	2.791e-182	599.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CH3_k127_7449432_1	1267535.KB906767_gene4724	3.963e-65	232.0	COG0577@1|root,COG0577@2|Bacteria	1267535.KB906767_gene4724|-	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_7465714_1	240016.ABIZ01000001_gene1588	2.84e-51	198.0	COG0673@1|root,COG0673@2|Bacteria,46TM9@74201|Verrucomicrobia,2ITZ3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CH3_k127_7465714_4	1158292.JPOE01000002_gene3555	6.695e-25	107.0	COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria,2VHIR@28216|Betaproteobacteria,1KMXP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	Subunit R is required for both nuclease and ATPase activities, but not for modification	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
CH3_k127_7465714_6	443143.GM18_2869	1.123e-09	61.0	COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria,42M86@68525|delta/epsilon subdivisions,2WIT1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Subunit R is required for both nuclease and ATPase activities, but not for modification	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
CH3_k127_7465714_3	1502851.FG93_02170	2.996e-43	181.0	COG3210@1|root,COG4625@1|root,COG3210@2|Bacteria,COG4625@2|Bacteria,1MU92@1224|Proteobacteria,2TSB7@28211|Alphaproteobacteria,3JUBZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Autotransporter beta-domain	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,Exo_endo_phos,PATR
CH3_k127_7465714_5	1210884.HG799465_gene12104	1.146e-15	89.0	2BRCH@1|root,32KB5@2|Bacteria,2J2TZ@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_7465714_7	1320556.AVBP01000012_gene3576	0.0001808	48.0	COG0342@1|root,COG0342@2|Bacteria,1NRIJ@1224|Proteobacteria,2UPCM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_7465714_2	1158292.JPOE01000002_gene3555	1.968e-45	170.0	COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria,2VHIR@28216|Betaproteobacteria,1KMXP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	Subunit R is required for both nuclease and ATPase activities, but not for modification	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
CH3_k127_7465714_0	314230.DSM3645_26609	2.327e-243	813.0	COG2010@1|root,COG2133@1|root,COG3828@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,COG3828@2|Bacteria,2IYH1@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,Cytochrom_C,Cytochrome_CBB3,Laminin_G_3,ThuA
CH3_k127_7474109_4	314230.DSM3645_29826	4.93e-09	66.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CH3_k127_7474109_2	756272.Plabr_0281	3.138e-11	72.0	COG4968@1|root,COG4968@2|Bacteria,2J53J@203682|Planctomycetes	203682|Planctomycetes	NU	Protein of unknown function (DUF1559)	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CH3_k127_7474109_3	344747.PM8797T_28619	1.158e-09	67.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CH3_k127_7474109_1	521674.Plim_3726	4.17e-13	81.0	COG2165@1|root,COG2165@2|Bacteria,2IYN2@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CH3_k127_7474109_5	1123242.JH636434_gene5550	4.437e-07	60.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CH3_k127_7474109_0	1403819.BATR01000195_gene6595	5.929e-33	133.0	COG5421@1|root,COG5421@2|Bacteria,46U8B@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
CH3_k127_7474109_6	265311.Mfl382	0.0004873	46.0	COG0204@1|root,COG0204@2|Bacteria,3WTAB@544448|Tenericutes	544448|Tenericutes	I	1-acyl-sn-glycerol-3-phosphate acyltransferase	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
CH3_k127_7482137_4	1210884.HG799464_gene10819	1.27e-84	283.0	COG1233@1|root,COG1233@2|Bacteria,2IYJC@203682|Planctomycetes	203682|Planctomycetes	Q	Flavin containing amine oxidoreductase	-	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
CH3_k127_7482137_14	278957.ABEA03000041_gene2243	1.227e-24	104.0	COG3727@1|root,COG3727@2|Bacteria,46VQU@74201|Verrucomicrobia,3K8JQ@414999|Opitutae	414999|Opitutae	L	DNA mismatch endonuclease Vsr	-	-	-	ko:K07458	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Vsr
CH3_k127_7482137_18	1123366.TH3_03429	7.083e-18	88.0	COG2335@1|root,COG2335@2|Bacteria,1RD06@1224|Proteobacteria,2U7H5@28211|Alphaproteobacteria,2JTP4@204441|Rhodospirillales	204441|Rhodospirillales	M	Four repeated domains in the Fasciclin I family of proteins, present in many other contexts.	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
CH3_k127_7482137_15	1335757.SPICUR_03845	3.463e-24	108.0	COG2199@1|root,COG3852@1|root,COG3706@2|Bacteria,COG3852@2|Bacteria,1R7HC@1224|Proteobacteria,1RZKN@1236|Gammaproteobacteria,1X0QN@135613|Chromatiales	135613|Chromatiales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS,PAS_9
CH3_k127_7482137_29	1123242.JH636438_gene5714	0.000683	47.0	COG4276@1|root,COG4276@2|Bacteria,2J0FI@203682|Planctomycetes	203682|Planctomycetes	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
CH3_k127_7482137_3	452637.Oter_1107	8.784e-105	349.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,46V45@74201|Verrucomicrobia	74201|Verrucomicrobia	K	helix_turn_helix, mercury resistance	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
CH3_k127_7482137_10	452637.Oter_1108	1.536e-56	203.0	COG2335@1|root,COG2335@2|Bacteria,46VJN@74201|Verrucomicrobia,3K9JN@414999|Opitutae	414999|Opitutae	M	Four repeated domains in the Fasciclin I family of proteins, present in many other contexts.	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
CH3_k127_7482137_8	240015.ACP_1727	7.219e-59	209.0	COG1028@1|root,COG1028@2|Bacteria	240015.ACP_1727|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_7482137_16	755178.Cyan10605_1738	2.633e-23	106.0	COG3829@1|root,COG5001@1|root,COG3829@2|Bacteria,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria	1117|Cyanobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_9,Response_reg
CH3_k127_7482137_1	1123242.JH636434_gene5621	5.239e-188	599.0	COG0702@1|root,COG0702@2|Bacteria,2IYQV@203682|Planctomycetes	203682|Planctomycetes	GM	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10
CH3_k127_7482137_11	452637.Oter_1109	1.2e-47	177.0	COG4276@1|root,COG4276@2|Bacteria,46X6Q@74201|Verrucomicrobia,3K9Y1@414999|Opitutae	414999|Opitutae	S	Pfam Polyketide cyclase dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_7482137_6	742725.HMPREF9450_01626	5.513e-66	252.0	COG1874@1|root,COG1874@2|Bacteria,4P500@976|Bacteroidetes	976|Bacteroidetes	G	Beta-galactosidase	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42
CH3_k127_7482137_21	547042.BACCOPRO_02222	1.884e-07	64.0	COG1649@1|root,COG1649@2|Bacteria	2|Bacteria	F	PFAM Uncharacterised BCR, COG1649	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Cu_amine_oxidN1,DUF3370,DUF4985,GHL10,Melibiase,Metallophos,MetallophosC,MetallophosN,SLH,WG_beta_rep
CH3_k127_7482137_2	886293.Sinac_3681	4.285e-119	411.0	COG1874@1|root,COG1874@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	bgaB	-	3.2.1.23	ko:K01190,ko:K12308	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_14,Glyco_hydro_42,Glyco_hydro_42M
CH3_k127_7482137_7	1396141.BATP01000047_gene3930	7.865e-65	227.0	COG3476@1|root,COG3476@2|Bacteria,46SXT@74201|Verrucomicrobia,2IVZD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	TspO/MBR family	-	-	-	-	-	-	-	-	-	-	-	-	TspO_MBR
CH3_k127_7482137_12	472759.Nhal_2122	1.952e-37	148.0	COG0702@1|root,COG0702@2|Bacteria,1QV7M@1224|Proteobacteria,1T2N4@1236|Gammaproteobacteria,1WYK0@135613|Chromatiales	135613|Chromatiales	GM	intermediate-associated protein 30	-	-	-	-	-	-	-	-	-	-	-	-	CIA30
CH3_k127_7482137_24	196367.JNFG01000216_gene660	5.108e-05	51.0	COG0702@1|root,COG0702@2|Bacteria,1MZ0C@1224|Proteobacteria,2VNMR@28216|Betaproteobacteria,1K4VX@119060|Burkholderiaceae	28216|Betaproteobacteria	GM	Nad-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_3,Epimerase,NAD_binding_10
CH3_k127_7482137_26	797303.Natpe_3981	0.0003006	46.0	COG2002@1|root,arCOG00812@2157|Archaea,2Y4G4@28890|Euryarchaeota,2404J@183963|Halobacteria	183963|Halobacteria	K	SpoVT / AbrB like domain	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
CH3_k127_7482137_20	743836.AYNA01000111_gene20	1.621e-09	64.0	COG1487@1|root,COG1487@2|Bacteria,1RJ2J@1224|Proteobacteria,2UA97@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	PFAM PilT protein domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PIN
CH3_k127_7482137_19	1123367.C666_16960	2.953e-11	72.0	COG1716@1|root,COG1716@2|Bacteria,1MW1M@1224|Proteobacteria,2VJ1K@28216|Betaproteobacteria,2KUV6@206389|Rhodocyclales	206389|Rhodocyclales	T	(FHA) domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
CH3_k127_7482137_25	1260356.D920_00417	0.0002794	47.0	COG1476@1|root,COG1476@2|Bacteria,1TVRT@1239|Firmicutes,4I3Z3@91061|Bacilli,4B5PU@81852|Enterococcaceae	91061|Bacilli	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_7482137_17	99598.Cal7507_5777	1.912e-20	112.0	2F43W@1|root,33WVC@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_7482137_9	340177.Cag_0614	7.569e-59	239.0	COG1357@1|root,COG2931@1|root,COG3210@1|root,COG4625@1|root,COG1357@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria	2|Bacteria	T	pathogenesis	rhgB	-	4.2.2.23	ko:K07004,ko:K18195	-	-	-	-	ko00000,ko01000	-	PL4	-	CBM-like,RhgB_N,fn3_3
CH3_k127_7482137_0	583355.Caka_2045	1.732e-263	919.0	COG0771@1|root,COG2911@1|root,COG2931@1|root,COG0771@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	murD	-	3.4.21.10,6.3.2.13,6.3.2.9	ko:K01317,ko:K01925,ko:K01928,ko:K01932	ko00300,ko00471,ko00550,ko01100,map00300,map00471,map00550,map01100	-	R02783,R02788	RC00064,RC00090,RC00141	ko00000,ko00001,ko01000,ko01002,ko01011,ko04131	-	-	-	DUF1727,Mur_ligase_C,Mur_ligase_M
CH3_k127_7482137_5	272134.KB731324_gene6505	3.064e-68	271.0	COG1404@1|root,COG2911@1|root,COG2931@1|root,COG3210@1|root,COG1404@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,1G7AR@1117|Cyanobacteria,1HBKR@1150|Oscillatoriales	1117|Cyanobacteria	OQ	PFAM FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
CH3_k127_7482137_23	926560.KE387027_gene1014	3.955e-07	68.0	COG2247@1|root,COG2247@2|Bacteria,1WNI9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	cell wall binding repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_7482137_22	926550.CLDAP_39920	2.288e-07	68.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	DUF1929,F5_F8_type_C,Glyco_hyd_65N_2,Glyco_hydro_18,He_PIG,PA14,RCC1,SLH
CH3_k127_7482137_13	696747.NIES39_O02270	6.184e-28	137.0	COG2931@1|root,COG4675@1|root,COG2931@2|Bacteria,COG4675@2|Bacteria,1GFPS@1117|Cyanobacteria,1HHVN@1150|Oscillatoriales	1117|Cyanobacteria	Q	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
CH3_k127_7505264_6	481448.Minf_1936	5.756e-20	98.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,46SA4@74201|Verrucomicrobia,37G1G@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4	-	-	SecD_SecF,Sec_GG
CH3_k127_7505264_7	289376.THEYE_A0281	5.764e-20	95.0	COG1862@1|root,COG1862@2|Bacteria,3J0UB@40117|Nitrospirae	40117|Nitrospirae	U	Preprotein translocase subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
CH3_k127_7505264_2	240016.ABIZ01000001_gene3247	1.16e-142	462.0	COG0075@1|root,COG0075@2|Bacteria,46SCI@74201|Verrucomicrobia,2IU5S@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
CH3_k127_7505264_5	497964.CfE428DRAFT_5371	9.899e-57	210.0	COG4121@1|root,COG4121@2|Bacteria	2|Bacteria	E	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34	mnmC	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0004808,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363	2.1.1.61,2.1.1.72,2.4.2.29,4.2.1.151	ko:K00773,ko:K07319,ko:K11782,ko:K15461	ko00130,ko01110,map00130,map01110	-	R00601,R03789,R08702,R10209,R10666	RC00003,RC00053,RC00060,RC00063,RC01483,RC03232	ko00000,ko00001,ko01000,ko02048,ko03016	-	-	-	DAO,Methyltransf_30
CH3_k127_7505264_9	671143.DAMO_2125	1.263e-14	77.0	COG0724@1|root,COG0724@2|Bacteria,2NPT0@2323|unclassified Bacteria	2|Bacteria	S	RNA recognition motif	rbpD	-	-	-	-	-	-	-	-	-	-	-	RRM_1
CH3_k127_7505264_8	382464.ABSI01000001_gene4245	1.135e-18	94.0	COG0727@1|root,COG0727@2|Bacteria	2|Bacteria	S	metal cluster binding	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
CH3_k127_7505264_4	497964.CfE428DRAFT_2716	2.03e-96	326.0	COG0533@1|root,COG0533@2|Bacteria,46SEH@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
CH3_k127_7505264_3	497964.CfE428DRAFT_2715	2.907e-124	412.0	COG0793@1|root,COG0793@2|Bacteria,46SM7@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
CH3_k127_7505264_1	497964.CfE428DRAFT_0809	3.276e-181	576.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,46TYP@74201|Verrucomicrobia	74201|Verrucomicrobia	CG	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_7505264_0	1396141.BATP01000006_gene5477	2.903e-261	825.0	COG1680@1|root,COG3876@1|root,COG1680@2|Bacteria,COG3876@2|Bacteria,46TDA@74201|Verrucomicrobia,2IV8Z@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CH3_k127_7520682_5	304371.MCP_2471	7.138e-07	53.0	COG0477@1|root,arCOG00130@2157|Archaea,2XU3E@28890|Euryarchaeota	28890|Euryarchaeota	G	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CH3_k127_7520682_7	1396141.BATP01000057_gene3046	6.21e-05	48.0	2AVZM@1|root,31MU0@2|Bacteria,46X67@74201|Verrucomicrobia,2IUMV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_7520682_2	386456.JQKN01000023_gene72	1.612e-76	264.0	arCOG01778@1|root,arCOG01778@2157|Archaea,2XU6W@28890|Euryarchaeota	28890|Euryarchaeota	Q	PFAM methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_31
CH3_k127_7520682_1	1121920.AUAU01000005_gene1005	1.618e-86	303.0	COG2271@1|root,COG2271@2|Bacteria,3Y98I@57723|Acidobacteria	57723|Acidobacteria	G	Organic Anion Transporter Polypeptide (OATP) family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CH3_k127_7520682_3	629265.PMA4326_14224	3.084e-13	75.0	2EKGR@1|root,33E6S@2|Bacteria,1NQ4Y@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_7520682_0	1173027.Mic7113_4793	2.61e-126	434.0	COG1680@1|root,COG1680@2|Bacteria,1G4D0@1117|Cyanobacteria,1HFEP@1150|Oscillatoriales	1117|Cyanobacteria	V	PFAM beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CH3_k127_7520682_4	1123368.AUIS01000001_gene1877	3.788e-10	63.0	COG0286@1|root,COG0286@2|Bacteria,1MW3A@1224|Proteobacteria,1RRVF@1236|Gammaproteobacteria,2NCS0@225057|Acidithiobacillales	225057|Acidithiobacillales	V	N-6 DNA Methylase	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_Mtase
CH3_k127_7529803_1	497964.CfE428DRAFT_5596	1.284e-145	466.0	COG0085@1|root,COG0085@2|Bacteria,46S8Q@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
CH3_k127_7529803_0	481448.Minf_0805	0.0	1728.0	COG0086@1|root,COG0086@2|Bacteria,46S79@74201|Verrucomicrobia,37G3C@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
CH3_k127_7562850_3	1121920.AUAU01000024_gene2382	1.053e-24	111.0	COG3303@1|root,COG4733@1|root,COG3303@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	4.2.2.1	ko:K01727	-	-	-	-	ko00000,ko01000	-	PL8	-	Big_2,DUF285,HYR,Laminin_G_3,Lyase_8,Lyase_8_C,Lyase_8_N,Paired_CXXCH_1,SLH,fn3
CH3_k127_7562850_2	579138.Zymop_1135	2.855e-26	115.0	COG1959@1|root,COG1959@2|Bacteria,1RGUG@1224|Proteobacteria,2UANJ@28211|Alphaproteobacteria,2K4GF@204457|Sphingomonadales	204457|Sphingomonadales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
CH3_k127_7562850_5	1121918.ARWE01000001_gene577	6.929e-05	55.0	COG1333@1|root,COG1333@2|Bacteria,1N6XE@1224|Proteobacteria,42NBB@68525|delta/epsilon subdivisions,2WIMD@28221|Deltaproteobacteria,43SZA@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	PFAM ResB family protein	-	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
CH3_k127_7562850_4	247490.KSU1_C0404	1.305e-18	99.0	COG1333@1|root,COG1333@2|Bacteria,2J0U6@203682|Planctomycetes	203682|Planctomycetes	O	ResB-like family	-	-	-	-	-	-	-	-	-	-	-	-	ResB
CH3_k127_7562850_0	665942.HMPREF1022_00427	8.121e-78	274.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,42MUG@68525|delta/epsilon subdivisions,2WISB@28221|Deltaproteobacteria,2M7UJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
CH3_k127_7562850_1	1232410.KI421421_gene3835	9.682e-28	123.0	COG0755@1|root,COG0755@2|Bacteria,1RG0A@1224|Proteobacteria,42N37@68525|delta/epsilon subdivisions,2WIKV@28221|Deltaproteobacteria,43W41@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Cytochrome C assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
CH3_k127_7657910_8	1123508.JH636443_gene4582	6.358e-26	112.0	COG1721@1|root,COG1721@2|Bacteria,2IY59@203682|Planctomycetes	203682|Planctomycetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CH3_k127_7657910_6	452637.Oter_0382	1.014e-85	289.0	COG2041@1|root,COG2041@2|Bacteria,46TCM@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Oxidoreductase molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
CH3_k127_7657910_5	756499.Desde_3002	5.841e-103	347.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,25ZZ7@186807|Peptococcaceae	186801|Clostridia	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
CH3_k127_7657910_2	1396141.BATP01000060_gene4642	2.34e-124	408.0	COG0592@1|root,COG0592@2|Bacteria,46SPK@74201|Verrucomicrobia,2ITMH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	-	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
CH3_k127_7657910_7	497964.CfE428DRAFT_6475	4.219e-58	211.0	COG2133@1|root,COG2133@2|Bacteria,46UM9@74201|Verrucomicrobia	2|Bacteria	G	Domain of Unknown Function (DUF1080)	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Calx-beta,DUF1080,F5_F8_type_C
CH3_k127_7657910_1	497964.CfE428DRAFT_4840	1.093e-195	622.0	COG0606@1|root,COG0606@2|Bacteria,46SAK@74201|Verrucomicrobia	74201|Verrucomicrobia	O	PFAM magnesium chelatase ChlI subunit	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
CH3_k127_7657910_4	204536.SULAZ_0984	8.444e-106	357.0	COG1060@1|root,COG1060@2|Bacteria,2G3M7@200783|Aquificae	200783|Aquificae	H	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate	mqnE	-	2.5.1.120	ko:K18285	ko00130,ko01110,map00130,map01110	-	R10667	RC00021,RC03234	ko00000,ko00001,ko01000	-	-	-	Fer4_14,Radical_SAM
CH3_k127_7657910_0	1396418.BATQ01000012_gene4420	1.716e-199	627.0	COG0133@1|root,COG0133@2|Bacteria,46SHR@74201|Verrucomicrobia,2ITRB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CH3_k127_7657910_13	794903.OPIT5_23755	5.622e-05	48.0	COG0179@1|root,COG0179@2|Bacteria,46SDD@74201|Verrucomicrobia,3K7IJ@414999|Opitutae	414999|Opitutae	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
CH3_k127_7657910_12	1303518.CCALI_02308	3.081e-12	77.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
CH3_k127_7657910_11	1123508.JH636446_gene6223	4.43e-13	79.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CH3_k127_7657910_9	272123.Anacy_5162	4.846e-17	96.0	COG0739@1|root,COG2931@1|root,COG0739@2|Bacteria,COG2931@2|Bacteria,1GQCK@1117|Cyanobacteria	1117|Cyanobacteria	Q	PFAM Hemolysin-type calcium-binding	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Calx-beta,DUF4347,HemolysinCabind,VCBS
CH3_k127_7657910_10	1303518.CCALI_00162	2.956e-13	81.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456,ko:K02650	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10,T2SSG
CH3_k127_7657910_3	794903.OPIT5_23755	5.628e-122	396.0	COG0179@1|root,COG0179@2|Bacteria,46SDD@74201|Verrucomicrobia,3K7IJ@414999|Opitutae	414999|Opitutae	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
CH3_k127_7677167_1	388051.AUFE01000129_gene4953	4.673e-06	49.0	COG3335@1|root,COG3335@2|Bacteria,1MW7X@1224|Proteobacteria,2VMDX@28216|Betaproteobacteria,1K2WH@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Elements of external origin	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_23
CH3_k127_7677167_2	402777.KB235904_gene3701	0.0001961	51.0	2E1K5@1|root,32WXN@2|Bacteria,1G8HZ@1117|Cyanobacteria	1117|Cyanobacteria	S	Immunity protein Imm1	-	-	-	-	-	-	-	-	-	-	-	-	Imm1
CH3_k127_7677167_0	1303518.CCALI_02834	3.698e-77	267.0	COG2377@1|root,COG2377@2|Bacteria	2|Bacteria	O	1,6-anhydro-N-acetyl-beta-muramic acid metabolic process	anmK	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237	2.7.1.170,4.2.1.126	ko:K07106,ko:K09001	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	iECABU_c1320.ECABU_c18930,iECED1_1282.ECED1_1841,ic_1306.c2032	AnmK
CH3_k127_7691536_4	1123073.KB899245_gene180	8.994e-45	172.0	COG1929@1|root,COG1929@2|Bacteria,1MVG9@1224|Proteobacteria,1RMC6@1236|Gammaproteobacteria,1X595@135614|Xanthomonadales	135614|Xanthomonadales	G	Belongs to the glycerate kinase type-1 family	glxK	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
CH3_k127_7691536_5	583355.Caka_1868	7.605e-41	155.0	COG0695@1|root,COG0695@2|Bacteria,46SXS@74201|Verrucomicrobia,3K871@414999|Opitutae	414999|Opitutae	O	Glutaredoxin	-	-	-	ko:K07390	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Glutaredoxin
CH3_k127_7691536_2	264732.Moth_0141	5.734e-84	291.0	COG0414@1|root,COG0414@2|Bacteria,1TP7A@1239|Firmicutes,248AN@186801|Clostridia,42F66@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
CH3_k127_7691536_0	880072.Desac_1581	3.459e-203	645.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,43BKD@68525|delta/epsilon subdivisions,2WJNK@28221|Deltaproteobacteria,2MR7G@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
CH3_k127_7691536_1	673860.AciM339_1573	2.256e-91	314.0	COG0182@1|root,arCOG01123@2157|Archaea,2Y86P@28890|Euryarchaeota,3F36H@33867|unclassified Euryarchaeota	28890|Euryarchaeota	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	-	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.23	ko:K03239,ko:K08963	ko00270,ko01100,ko03013,map00270,map01100,map03013	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000,ko03012	-	-	-	IF-2B
CH3_k127_7691536_3	1168034.FH5T_01595	1.222e-81	289.0	COG1520@1|root,COG1520@2|Bacteria,4P28I@976|Bacteroidetes,2FX0J@200643|Bacteroidia	976|Bacteroidetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CH3_k127_7704843_16	1313304.CALK_1498	3.128e-72	250.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CH3_k127_7704843_4	1313304.CALK_1497	9.02e-140	455.0	COG0399@1|root,COG0399@2|Bacteria	2|Bacteria	E	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
CH3_k127_7704843_5	179408.Osc7112_2512	1.309e-135	439.0	COG0714@1|root,COG0714@2|Bacteria,1G0WS@1117|Cyanobacteria,1H9JV@1150|Oscillatoriales	1117|Cyanobacteria	O	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CH3_k127_7704843_8	56107.Cylst_0588	1.6e-119	399.0	COG1721@1|root,COG1721@2|Bacteria,1G1ZM@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CH3_k127_7704843_14	756067.MicvaDRAFT_0417	4.231e-106	372.0	COG1305@1|root,COG1305@2|Bacteria,1G1YY@1117|Cyanobacteria,1HA69@1150|Oscillatoriales	1117|Cyanobacteria	E	SMART Transglutaminase-like	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
CH3_k127_7704843_20	382464.ABSI01000010_gene3682	1.82e-18	97.0	COG1459@1|root,COG1459@2|Bacteria	2|Bacteria	U	protein transport across the cell outer membrane	pilC	GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009297,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0016043,GO:0022607,GO:0030030,GO:0030031,GO:0032940,GO:0033036,GO:0042886,GO:0043711,GO:0044085,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0098776	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
CH3_k127_7704843_19	935948.KE386495_gene2110	1.202e-37	144.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia,42GS3@68295|Thermoanaerobacterales	186801|Clostridia	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
CH3_k127_7704843_18	247490.KSU1_C0572	3.963e-45	175.0	COG0115@1|root,COG0115@2|Bacteria,2J20K@203682|Planctomycetes	203682|Planctomycetes	EH	Amino-transferase class IV	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_4
CH3_k127_7704843_12	1122947.FR7_2048	8.609e-107	363.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,4H6Y8@909932|Negativicutes	909932|Negativicutes	EH	Anthranilate synthase component I, N terminal region	-	-	2.6.1.85	ko:K01665	ko00790,map00790	-	R01716	RC00010,RC01418	ko00000,ko00001,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
CH3_k127_7704843_17	861299.J421_0058	2.331e-67	239.0	COG1611@1|root,COG1611@2|Bacteria,1ZT7E@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
CH3_k127_7704843_15	521045.Kole_0981	4.86e-79	276.0	COG0524@1|root,COG0524@2|Bacteria,2GDS1@200918|Thermotogae	200918|Thermotogae	H	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
CH3_k127_7704843_6	1268240.ATFI01000008_gene2321	4.695e-132	435.0	COG2271@1|root,COG2271@2|Bacteria,4NH5M@976|Bacteroidetes,2FNV1@200643|Bacteroidia,4AMZP@815|Bacteroidaceae	976|Bacteroidetes	G	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K07783	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.1.4.4,2.A.1.4.6	-	-	MFS_1
CH3_k127_7704843_9	1499967.BAYZ01000182_gene4442	1.301e-118	390.0	COG0673@1|root,COG0673@2|Bacteria,2NQJN@2323|unclassified Bacteria	2|Bacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	iolG	-	1.1.1.18,1.1.1.369	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	-	R01183,R09951	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CH3_k127_7704843_10	926550.CLDAP_26140	8.305e-118	386.0	COG1082@1|root,COG1082@2|Bacteria,2G613@200795|Chloroflexi	200795|Chloroflexi	G	Xylose isomerase-like TIM barrel	-	-	4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
CH3_k127_7704843_0	485913.Krac_4320	4.401e-257	813.0	COG3962@1|root,COG3962@2|Bacteria,2G68S@200795|Chloroflexi	200795|Chloroflexi	E	Thiamine pyrophosphate enzyme, central domain	-	-	3.7.1.22	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R08603	RC02331	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CH3_k127_7704843_3	485913.Krac_4319	2.724e-141	456.0	COG0524@1|root,COG0524@2|Bacteria,2G5XM@200795|Chloroflexi	200795|Chloroflexi	G	pfkB family carbohydrate kinase	-	-	2.7.1.92	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R05661	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
CH3_k127_7704843_13	649349.Lbys_0013	1.356e-106	354.0	COG3718@1|root,COG3718@2|Bacteria,4NKW4@976|Bacteroidetes,47TKD@768503|Cytophagia	976|Bacteroidetes	G	KduI/IolB family	-	-	5.3.1.30	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R08503	RC00541	ko00000,ko00001,ko01000	-	-	-	KduI
CH3_k127_7704843_11	481448.Minf_0287	3.903e-112	372.0	COG0191@1|root,COG0191@2|Bacteria,46TAJ@74201|Verrucomicrobia,37GA3@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	G	Fructose-bisphosphate aldolase class-II	-	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
CH3_k127_7704843_2	344747.PM8797T_29708	5.036e-180	573.0	COG4409@1|root,COG4409@2|Bacteria,2IYPT@203682|Planctomycetes	2|Bacteria	G	BNR repeat-like domain	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,Big_2,DUF4091,FIVAR,Laminin_G_3
CH3_k127_7704843_1	497964.CfE428DRAFT_1457	1.677e-198	633.0	COG2804@1|root,COG2804@2|Bacteria,46SDR@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	General secretory system II protein E domain protein	pulE	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
CH3_k127_7704843_7	313628.LNTAR_05914	6.159e-123	400.0	COG2805@1|root,COG2805@2|Bacteria	2|Bacteria	NU	Type II/IV secretion system protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
CH3_k127_771809_6	1173028.ANKO01000017_gene228	4.326e-83	284.0	COG0068@1|root,COG0068@2|Bacteria,1G063@1117|Cyanobacteria,1H71F@1150|Oscillatoriales	1117|Cyanobacteria	O	Belongs to the carbamoyltransferase HypF family	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
CH3_k127_771809_11	518766.Rmar_2594	1.395e-27	113.0	COG0298@1|root,COG0298@2|Bacteria,4NX9T@976|Bacteroidetes	976|Bacteroidetes	O	PFAM hydrogenase expression formation protein (HUPF HYPC)	-	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
CH3_k127_771809_2	204669.Acid345_1705	2.121e-178	568.0	COG0409@1|root,COG0409@2|Bacteria,3Y405@57723|Acidobacteria,2JIK0@204432|Acidobacteriia	204432|Acidobacteriia	O	Hydrogenase formation hypA family	-	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
CH3_k127_771809_3	56110.Oscil6304_5908	2.63e-149	480.0	COG0309@1|root,COG0309@2|Bacteria,1G1Z7@1117|Cyanobacteria,1H82T@1150|Oscillatoriales	1117|Cyanobacteria	O	hydrogenase expression formation protein HypE	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
CH3_k127_771809_12	313628.LNTAR_17808	2.324e-10	70.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
CH3_k127_771809_5	234267.Acid_5336	2.253e-120	424.0	COG0642@1|root,COG0784@1|root,COG3292@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,3Y3IC@57723|Acidobacteria	57723|Acidobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
CH3_k127_771809_13	177437.HRM2_37840	1.142e-05	55.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42NWT@68525|delta/epsilon subdivisions,2X5DA@28221|Deltaproteobacteria,2MMYJ@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
CH3_k127_771809_7	497964.CfE428DRAFT_2826	1.244e-61	219.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CH3_k127_771809_1	497964.CfE428DRAFT_2825	2.342e-196	657.0	COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,46TEF@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Von Willebrand factor	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	DUF3520,VWA,VWA_3,vWF_A
CH3_k127_771809_0	497964.CfE428DRAFT_2824	0.0	2722.0	2DBSP@1|root,2ZAT9@2|Bacteria,46TYZ@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_771809_8	269799.Gmet_2492	9.44e-60	215.0	COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,42QQ3@68525|delta/epsilon subdivisions,2WNPH@28221|Deltaproteobacteria,43U0C@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
CH3_k127_771809_10	236097.ADG881_2747	1.371e-34	138.0	COG0346@1|root,COG0346@2|Bacteria,1N8P0@1224|Proteobacteria,1SGYP@1236|Gammaproteobacteria,1XPDJ@135619|Oceanospirillales	135619|Oceanospirillales	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CH3_k127_771809_4	671143.DAMO_0981	1.667e-130	423.0	COG1013@1|root,COG1145@1|root,COG1013@2|Bacteria,COG1145@2|Bacteria,2NQV4@2323|unclassified Bacteria	2|Bacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
CH3_k127_7720927_12	497964.CfE428DRAFT_4734	1.054e-21	99.0	COG2433@1|root,COG2433@2|Bacteria,46Z8U@74201|Verrucomicrobia	2|Bacteria	S	PFAM transposase IS66	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
CH3_k127_7720927_1	266264.Rmet_1273	2.428e-129	423.0	COG4974@1|root,COG4974@2|Bacteria,1MXZX@1224|Proteobacteria,2VICA@28216|Betaproteobacteria,1K65J@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
CH3_k127_7720927_4	1267535.KB906767_gene1216	4.447e-96	324.0	COG0582@1|root,COG0582@2|Bacteria,3Y5HJ@57723|Acidobacteria	57723|Acidobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
CH3_k127_7720927_3	1267535.KB906767_gene1215	2.595e-98	335.0	COG4974@1|root,COG4974@2|Bacteria,3Y7QG@57723|Acidobacteria	57723|Acidobacteria	L	phage integrase domain protein SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
CH3_k127_7720927_11	497964.CfE428DRAFT_4690	1.551e-26	110.0	COG2433@1|root,COG2433@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
CH3_k127_7720927_14	886293.Sinac_3736	2.047e-07	62.0	COG2165@1|root,COG2165@2|Bacteria,2J1QS@203682|Planctomycetes	203682|Planctomycetes	NU	TIGRFAM prepilin-type N-terminal cleavage methylation domain	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CH3_k127_7720927_13	661478.OP10G_0369	1.515e-16	91.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02650,ko:K02679	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10
CH3_k127_7720927_7	452637.Oter_3865	9.318e-60	213.0	COG0307@1|root,COG0307@2|Bacteria,46SU1@74201|Verrucomicrobia,3K7ZH@414999|Opitutae	414999|Opitutae	H	TIGRFAM riboflavin synthase, alpha subunit	-	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
CH3_k127_7720927_8	1132836.RCCGE510_07356	1.453e-46	172.0	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,2U9BV@28211|Alphaproteobacteria,4BE03@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
CH3_k127_7720927_10	478741.JAFS01000001_gene1905	1.516e-37	146.0	COG0511@1|root,COG0511@2|Bacteria,46SXA@74201|Verrucomicrobia,37GQ9@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
CH3_k127_7720927_0	497964.CfE428DRAFT_2953	3.344e-199	630.0	COG0439@1|root,COG0439@2|Bacteria,46SIE@74201|Verrucomicrobia	74201|Verrucomicrobia	I	acetyl-CoA carboxylase	-	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
CH3_k127_7720927_9	240015.ACP_2565	2.747e-46	171.0	COG0838@1|root,COG0838@2|Bacteria,3Y8B8@57723|Acidobacteria,2JN67@204432|Acidobacteriia	204432|Acidobacteriia	C	NADH-ubiquinone/plastoquinone oxidoreductase, chain 3	-	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
CH3_k127_7720927_2	1267534.KB906754_gene3780	3.37e-103	338.0	COG0377@1|root,COG0377@2|Bacteria,3Y74G@57723|Acidobacteria,2JKT1@204432|Acidobacteriia	204432|Acidobacteriia	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	-	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
CH3_k127_7720927_5	1267534.KB906754_gene3779	1.88e-90	306.0	COG0852@1|root,COG0852@2|Bacteria,3Y72R@57723|Acidobacteria,2JM53@204432|Acidobacteriia	204432|Acidobacteriia	C	Respiratory-chain NADH dehydrogenase, 30 Kd subunit	-	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
CH3_k127_7720927_6	1267534.KB906754_gene3778	1.422e-87	292.0	COG0649@1|root,COG0649@2|Bacteria,3Y6MU@57723|Acidobacteria,2JKN7@204432|Acidobacteriia	204432|Acidobacteriia	C	Respiratory-chain NADH dehydrogenase, 49 Kd subunit	-	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
CH3_k127_7744876_0	497964.CfE428DRAFT_3502	8.485e-219	694.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,46THN@74201|Verrucomicrobia	74201|Verrucomicrobia	CG	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
CH3_k127_7756423_1	641524.ADICYQ_3837	1.202e-102	344.0	28MHM@1|root,2ZAUH@2|Bacteria,4NKMG@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_7756423_0	743299.Acife_2330	2.928e-141	464.0	COG3385@1|root,COG3385@2|Bacteria,1RA6A@1224|Proteobacteria,1SDJ1@1236|Gammaproteobacteria,2NDQ9@225057|Acidithiobacillales	225057|Acidithiobacillales	L	PFAM Transposase, IS4-like	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
CH3_k127_7756423_9	713587.THITH_06560	8.226e-05	45.0	COG1752@1|root,COG1752@2|Bacteria,1Q82E@1224|Proteobacteria,1RRUE@1236|Gammaproteobacteria,1X1AV@135613|Chromatiales	135613|Chromatiales	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
CH3_k127_7756423_3	251221.35210810	1.127e-53	213.0	COG5295@1|root,COG5295@2|Bacteria,1GB93@1117|Cyanobacteria	1117|Cyanobacteria	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_7756423_7	264462.Bd2582	2.083e-05	58.0	COG2911@1|root,COG3210@1|root,COG2911@2|Bacteria,COG3210@2|Bacteria,1NED3@1224|Proteobacteria,42WDX@68525|delta/epsilon subdivisions,2MTVC@213481|Bdellovibrionales,2WRDH@28221|Deltaproteobacteria	213481|Bdellovibrionales	U	cell wall surface anchor family protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74
CH3_k127_7756423_5	324602.Caur_0299	1.127e-22	115.0	COG5295@1|root,COG5295@2|Bacteria,2GB82@200795|Chloroflexi,377IZ@32061|Chloroflexia	32061|Chloroflexia	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectinesterase
CH3_k127_7756423_2	335543.Sfum_0920	5.391e-67	241.0	COG0500@1|root,COG1846@1|root,COG1846@2|Bacteria,COG2226@2|Bacteria,1MW7J@1224|Proteobacteria,43BRY@68525|delta/epsilon subdivisions,2X72R@28221|Deltaproteobacteria,2MQCD@213462|Syntrophobacterales	28221|Deltaproteobacteria	KQ	Dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
CH3_k127_7756423_4	497964.CfE428DRAFT_1407	3.294e-26	115.0	COG0582@1|root,COG0582@2|Bacteria,46W0S@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
CH3_k127_7756423_8	926560.KE387028_gene234	5.622e-05	48.0	COG0286@1|root,COG0286@2|Bacteria,1WI3E@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	HsdM N-terminal domain	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
CH3_k127_7756423_6	717605.Theco_3395	1.568e-17	91.0	COG2931@1|root,COG2931@2|Bacteria,1V022@1239|Firmicutes,4HFJ6@91061|Bacilli,26SF3@186822|Paenibacillaceae	91061|Bacilli	Q	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
CH3_k127_7788749_23	1121445.ATUZ01000020_gene2153	0.000111	51.0	COG2755@1|root,COG2755@2|Bacteria,1P2JM@1224|Proteobacteria	1224|Proteobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_7788749_21	1151117.AJLF01000001_gene1466	3.862e-12	79.0	COG0463@1|root,arCOG00894@2157|Archaea,2XWXA@28890|Euryarchaeota,242RY@183968|Thermococci	183968|Thermococci	M	GtrA-like protein	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2,GtrA
CH3_k127_7788749_2	56780.SYN_02389	3.953e-162	531.0	COG1807@1|root,COG1807@2|Bacteria,1P6JE@1224|Proteobacteria,42QEZ@68525|delta/epsilon subdivisions,2WKYB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CH3_k127_7788749_10	1123354.AUDR01000001_gene2018	1.655e-83	287.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,2VJ5G@28216|Betaproteobacteria,1KRK3@119069|Hydrogenophilales	1224|Proteobacteria	M	Glycosyl transferase family 2	arnC	GO:0000271,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0030258,GO:0030259,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
CH3_k127_7788749_3	1123354.AUDR01000001_gene2019	4.093e-145	468.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2VJDZ@28216|Betaproteobacteria,1KTB7@119069|Hydrogenophilales	119069|Hydrogenophilales	M	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	1.17.1.1	ko:K12452	ko00520,map00520	-	R03391,R03392	RC00230	ko00000,ko00001,ko01000	-	-	-	DegT_DnrJ_EryC1
CH3_k127_7788749_17	694440.JOMF01000004_gene1346	2.056e-48	186.0	COG0673@1|root,arCOG01622@2157|Archaea,2XTZY@28890|Euryarchaeota,2N9E7@224756|Methanomicrobia	224756|Methanomicrobia	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	1.1.1.374	ko:K18855	-	-	-	-	ko00000,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CH3_k127_7788749_20	469618.FVAG_00642	3.837e-23	103.0	COG3952@1|root,COG3952@2|Bacteria,37AN1@32066|Fusobacteria	32066|Fusobacteria	S	Lipid A Biosynthesis N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	LAB_N
CH3_k127_7788749_15	1286106.MPL1_00887	8.811e-65	243.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CH3_k127_7788749_19	1217656.F964_03877	1.254e-24	114.0	COG2020@1|root,COG2020@2|Bacteria,1RJNV@1224|Proteobacteria,1SGB2@1236|Gammaproteobacteria,3NKGV@468|Moraxellaceae	1236|Gammaproteobacteria	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
CH3_k127_7788749_13	1403819.BATR01000112_gene3842	4.869e-74	258.0	COG0745@1|root,COG0745@2|Bacteria	1403819.BATR01000112_gene3842|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_7788749_9	240016.ABIZ01000001_gene5833	8.277e-84	293.0	COG0642@1|root,COG2205@2|Bacteria,46V7H@74201|Verrucomicrobia	74201|Verrucomicrobia	T	HAMP domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
CH3_k127_7788749_4	1149133.ppKF707_4753	4.427e-130	441.0	COG1368@1|root,COG1368@2|Bacteria,1MVCM@1224|Proteobacteria,1RYKY@1236|Gammaproteobacteria,1YFQD@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	M	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CH3_k127_7788749_22	1117108.PAALTS15_19168	2.146e-08	64.0	COG0726@1|root,COG3291@1|root,COG5184@1|root,COG5276@1|root,COG5434@1|root,COG0726@2|Bacteria,COG3291@2|Bacteria,COG5184@2|Bacteria,COG5276@2|Bacteria,COG5434@2|Bacteria,1UYD0@1239|Firmicutes,4HVHQ@91061|Bacilli,26U3Z@186822|Paenibacillaceae	91061|Bacilli	M	alpha-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,F5_F8_type_C
CH3_k127_7788749_1	497964.CfE428DRAFT_1569	4.222e-190	612.0	COG0568@1|root,COG0568@2|Bacteria,46S6M@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
CH3_k127_7788749_8	240016.ABIZ01000001_gene5347	2.286e-85	295.0	COG1596@1|root,COG1596@2|Bacteria,46XCW@74201|Verrucomicrobia,2IVGU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Polysaccharide biosynthesis/export protein	-	-	-	-	-	-	-	-	-	-	-	-	Poly_export,SLBB
CH3_k127_7788749_7	1123070.KB899258_gene1891	9.653e-88	310.0	COG1596@1|root,COG1596@2|Bacteria,46ZHY@74201|Verrucomicrobia,2IUWB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Polysaccharide biosynthesis/export protein	-	-	-	-	-	-	-	-	-	-	-	-	Poly_export,SLBB
CH3_k127_7788749_18	240016.ABIZ01000001_gene5349	2.193e-44	184.0	COG1596@1|root,COG3206@1|root,COG1596@2|Bacteria,COG3206@2|Bacteria,46ZHY@74201|Verrucomicrobia,2IUWB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Polysaccharide biosynthesis/export protein	-	-	-	-	-	-	-	-	-	-	-	-	Poly_export,SLBB
CH3_k127_7788749_16	240016.ABIZ01000001_gene5350	4.079e-64	230.0	COG3267@1|root,COG3267@2|Bacteria,46XMZ@74201|Verrucomicrobia,2IW82@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
CH3_k127_7788749_12	1128421.JAGA01000003_gene2817	8.821e-75	259.0	COG0596@1|root,COG0596@2|Bacteria,2NQV9@2323|unclassified Bacteria	2|Bacteria	S	Alpha/beta hydrolase family	ybfF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016787,GO:0016788,GO:0016790,GO:0044424,GO:0044444,GO:0044464,GO:0052689	-	ko:K01175	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
CH3_k127_7788749_11	1396141.BATP01000030_gene3705	8.348e-80	274.0	COG2197@1|root,COG2197@2|Bacteria,46V5W@74201|Verrucomicrobia	74201|Verrucomicrobia	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CH3_k127_7788749_5	1396141.BATP01000030_gene3706	5.15e-95	346.0	COG0642@1|root,COG4251@1|root,COG2205@2|Bacteria,COG4251@2|Bacteria,46UHX@74201|Verrucomicrobia,2IVRU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
CH3_k127_7788749_0	1254432.SCE1572_30430	9.351e-221	698.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,42N0C@68525|delta/epsilon subdivisions,2X250@28221|Deltaproteobacteria,2YXZE@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CH3_k127_7788749_6	497964.CfE428DRAFT_1931	4.672e-91	309.0	COG1940@1|root,COG1940@2|Bacteria	2|Bacteria	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
CH3_k127_7788749_14	105559.Nwat_2046	5.134e-74	250.0	COG1225@1|root,COG1225@2|Bacteria,1R9YF@1224|Proteobacteria,1S37E@1236|Gammaproteobacteria,1WWWB@135613|Chromatiales	135613|Chromatiales	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CH3_k127_7828050_18	1396418.BATQ01000167_gene1757	5.213e-66	241.0	COG0457@1|root,COG1450@1|root,COG0457@2|Bacteria,COG1450@2|Bacteria,46TXY@74201|Verrucomicrobia,2ITGX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	NU	Bacterial type II and III secretion system protein	-	-	-	-	-	-	-	-	-	-	-	-	Secretin,TPR_16,TPR_8
CH3_k127_7828050_25	497964.CfE428DRAFT_4746	2.946e-41	168.0	COG0258@1|root,COG0258@2|Bacteria,46SWB@74201|Verrucomicrobia	74201|Verrucomicrobia	L	5'-3' exonuclease	exo	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N
CH3_k127_7828050_23	575540.Isop_0876	5.901e-48	194.0	COG2931@1|root,COG2931@2|Bacteria,2J1K0@203682|Planctomycetes	203682|Planctomycetes	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_7828050_36	1396141.BATP01000058_gene1991	4.187e-06	60.0	COG1572@1|root,COG2010@1|root,COG2133@1|root,COG1572@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,46TW3@74201|Verrucomicrobia,2IVDX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
CH3_k127_7828050_13	382464.ABSI01000013_gene1839	1.727e-97	358.0	COG1404@1|root,COG1520@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,46UMW@74201|Verrucomicrobia,2IUFG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,Peptidase_S8
CH3_k127_7828050_29	251221.35213566	8.598e-30	139.0	COG1404@1|root,COG5549@1|root,COG1404@2|Bacteria,COG5549@2|Bacteria,1G72X@1117|Cyanobacteria	1117|Cyanobacteria	O	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_7828050_31	404380.Gbem_1922	1.448e-23	119.0	COG1361@1|root,COG3055@1|root,COG3420@1|root,COG5184@1|root,COG1361@2|Bacteria,COG3055@2|Bacteria,COG3420@2|Bacteria,COG5184@2|Bacteria,1R504@1224|Proteobacteria,42QHC@68525|delta/epsilon subdivisions,2WKUI@28221|Deltaproteobacteria,43VN4@69541|Desulfuromonadales	28221|Deltaproteobacteria	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	RCC1,RCC1_2
CH3_k127_7828050_26	290397.Adeh_2684	3.757e-41	158.0	COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,42RI5@68525|delta/epsilon subdivisions,2WPDF@28221|Deltaproteobacteria,2YVGY@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
CH3_k127_7828050_27	1396141.BATP01000034_gene4147	7.819e-37	149.0	COG3189@1|root,COG3189@2|Bacteria,46VV6@74201|Verrucomicrobia,2IWA9@203494|Verrucomicrobiae	2|Bacteria	S	Protein of unknown function, DUF488	yeaO	-	-	-	-	-	-	-	-	-	-	-	DUF488
CH3_k127_7828050_1	525904.Tter_0327	5.507e-282	884.0	COG0296@1|root,COG0296@2|Bacteria	2|Bacteria	G	1,4-alpha-glucan branching enzyme activity	glgB	GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0055114,GO:0071704,GO:0071944,GO:1901576	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
CH3_k127_7828050_39	1207075.PputUW4_04220	0.0001286	52.0	COG3708@1|root,COG3708@2|Bacteria,1NBPE@1224|Proteobacteria,1SFP2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	-	-	-	ko:K13653	-	-	-	-	ko00000,ko03000	-	-	-	Cass2,GyrI-like
CH3_k127_7828050_12	323261.Noc_2734	1.858e-117	390.0	COG1449@1|root,COG1449@2|Bacteria,1R5KI@1224|Proteobacteria,1S0ID@1236|Gammaproteobacteria,1WXJ4@135613|Chromatiales	135613|Chromatiales	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_57
CH3_k127_7828050_4	472759.Nhal_0095	5.016e-231	724.0	COG0297@1|root,COG0297@2|Bacteria,1P7F2@1224|Proteobacteria,1RZVJ@1236|Gammaproteobacteria,1WX4C@135613|Chromatiales	135613|Chromatiales	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	-	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
CH3_k127_7828050_7	1283300.ATXB01000001_gene664	5.201e-169	540.0	COG0366@1|root,COG0366@2|Bacteria,1MWBZ@1224|Proteobacteria,1RYKS@1236|Gammaproteobacteria,1XFWC@135618|Methylococcales	135618|Methylococcales	G	Alpha amylase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	hDGE_amylase
CH3_k127_7828050_3	243233.MCA2119	4.045e-257	799.0	COG1449@1|root,COG1449@2|Bacteria,1R3Z3@1224|Proteobacteria,1RNRC@1236|Gammaproteobacteria,1XG1U@135618|Methylococcales	135618|Methylococcales	G	Glycosyl hydrolase family 57	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_57
CH3_k127_7828050_21	1384056.N787_02850	1.246e-51	198.0	2F24D@1|root,33V2Z@2|Bacteria,1NV0Y@1224|Proteobacteria,1SN7D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_7828050_14	269799.Gmet_1782	5.694e-89	301.0	COG0861@1|root,COG0861@2|Bacteria,1MWC9@1224|Proteobacteria,42MZB@68525|delta/epsilon subdivisions,2WKV4@28221|Deltaproteobacteria,43TDE@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Integral membrane protein TerC family	-	-	-	-	-	-	-	-	-	-	-	-	TerC
CH3_k127_7828050_20	257314.LJ_0003	1.423e-61	226.0	COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,4HA0W@91061|Bacilli,3F3Q1@33958|Lactobacillaceae	91061|Bacilli	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
CH3_k127_7828050_8	452637.Oter_2109	9.17e-168	535.0	COG0180@1|root,COG0180@2|Bacteria,46SA6@74201|Verrucomicrobia,3K7UW@414999|Opitutae	414999|Opitutae	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
CH3_k127_7828050_38	867845.KI911784_gene1416	1.39e-05	54.0	2EGCD@1|root,33A46@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1707,DUF4190
CH3_k127_7828050_32	278957.ABEA03000041_gene2093	1.242e-19	100.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,46SA4@74201|Verrucomicrobia,3K770@414999|Opitutae	414999|Opitutae	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4	-	-	SecD_SecF,Sec_GG
CH3_k127_7828050_16	1499967.BAYZ01000095_gene4228	1.211e-74	258.0	COG0681@1|root,COG0681@2|Bacteria	2|Bacteria	U	signal peptide processing	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
CH3_k127_7828050_0	1396141.BATP01000032_gene4423	4.672e-284	891.0	COG5297@1|root,COG5297@2|Bacteria,46UD4@74201|Verrucomicrobia,2IVIH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Belongs to the glycosyl hydrolase family 6	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_7828050_15	1297742.A176_07035	1.671e-81	303.0	COG0860@1|root,COG0860@2|Bacteria,1NTG0@1224|Proteobacteria	1224|Proteobacteria	M	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_3
CH3_k127_7828050_28	1089550.ATTH01000001_gene181	7.483e-31	130.0	COG1678@1|root,COG1678@2|Bacteria,4NFQA@976|Bacteroidetes,1FJDT@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	K	Belongs to the UPF0301 (AlgH) family	-	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
CH3_k127_7828050_33	316274.Haur_4882	1.081e-12	79.0	2EE19@1|root,337W3@2|Bacteria,2G8U2@200795|Chloroflexi,375HC@32061|Chloroflexia	32061|Chloroflexia	S	PFAM LIM, zinc-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	DA1-like
CH3_k127_7828050_5	330214.NIDE2536	7.323e-217	689.0	COG0021@1|root,COG0021@2|Bacteria,3J0MM@40117|Nitrospirae	40117|Nitrospirae	G	Transketolase, pyrimidine binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
CH3_k127_7828050_2	497964.CfE428DRAFT_0818	1.054e-281	891.0	COG0046@1|root,COG0046@2|Bacteria,46S8Y@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,GATase_5
CH3_k127_7828050_17	886293.Sinac_2497	6.462e-74	281.0	COG1595@1|root,COG2373@1|root,COG1595@2|Bacteria,COG2373@2|Bacteria	2|Bacteria	U	Large extracellular alpha-helical protein	-	-	-	ko:K03088,ko:K06894	-	-	-	-	ko00000,ko03021	-	-	-	A2M_N,CarboxypepD_reg,Sigma70_r2,Sigma70_r4_2
CH3_k127_7828050_10	1403819.BATR01000183_gene6316	5.169e-122	408.0	COG3637@1|root,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp,OMP_b-brl
CH3_k127_7828050_6	2340.JV46_09630	3.975e-191	608.0	COG3303@1|root,COG3303@2|Bacteria,1P8CP@1224|Proteobacteria,1RQGG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Seven times multi-haem cytochrome CxxCH	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Multi-haem_cyto
CH3_k127_7828050_9	448385.sce4706	4.077e-142	464.0	COG5557@1|root,COG5557@2|Bacteria,1PFX4@1224|Proteobacteria,42NUN@68525|delta/epsilon subdivisions,2WJHN@28221|Deltaproteobacteria,2YWI0@29|Myxococcales	28221|Deltaproteobacteria	C	Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
CH3_k127_7828050_11	583355.Caka_0067	8.977e-119	389.0	COG0437@1|root,COG0437@2|Bacteria,46S66@74201|Verrucomicrobia,3K7GM@414999|Opitutae	2|Bacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11,Fer4_4,Fer4_7
CH3_k127_7828050_30	706587.Desti_4133	3.28e-26	118.0	28JYU@1|root,2Z9NZ@2|Bacteria,1N5J2@1224|Proteobacteria,42UJJ@68525|delta/epsilon subdivisions,2X7XY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_7828050_24	497964.CfE428DRAFT_2435	8.264e-47	177.0	COG0546@1|root,COG0546@2|Bacteria,46SW1@74201|Verrucomicrobia	74201|Verrucomicrobia	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD,HAD_2
CH3_k127_7828050_37	1385521.N803_05605	6.086e-06	52.0	COG2148@1|root,COG2148@2|Bacteria,2GK0M@201174|Actinobacteria,4FG9T@85021|Intrasporangiaceae	201174|Actinobacteria	M	sugar transferase	epsL	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
CH3_k127_7828050_22	1192034.CAP_8221	2.248e-49	191.0	2C9T2@1|root,347D0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_7828050_19	240016.ABIZ01000001_gene621	1.971e-65	237.0	COG4714@1|root,COG4714@2|Bacteria,46WYQ@74201|Verrucomicrobia,2IUN8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF2167)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2167
CH3_k127_7829976_8	497964.CfE428DRAFT_4273	1.798e-70	244.0	COG1493@1|root,COG1493@2|Bacteria,46S64@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
CH3_k127_7829976_5	794903.OPIT5_28075	1.995e-93	312.0	COG1137@1|root,COG1137@2|Bacteria,46SDI@74201|Verrucomicrobia,3K77F@414999|Opitutae	414999|Opitutae	S	ABC transporter	-	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran
CH3_k127_7829976_2	497964.CfE428DRAFT_4290	3.332e-167	535.0	COG0448@1|root,COG0448@2|Bacteria,46SG2@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Belongs to the bacterial plant glucose-1-phosphate adenylyltransferase family	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
CH3_k127_7829976_11	269482.Bcep1808_6245	2.641e-21	96.0	COG3039@1|root,COG3039@2|Bacteria,1MVDK@1224|Proteobacteria,2VI1H@28216|Betaproteobacteria,1K3UX@119060|Burkholderiaceae	28216|Betaproteobacteria	L	PFAM transposase, IS4 family protein	-	-	-	ko:K07481	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DUF772
CH3_k127_7829976_10	1210884.HG799462_gene8243	1.429e-38	160.0	2F56K@1|root,33XTB@2|Bacteria,2J30K@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_7829976_3	1123242.JH636434_gene4668	1.987e-157	520.0	COG1520@1|root,COG3221@1|root,COG1520@2|Bacteria,COG3221@2|Bacteria,2J1S1@203682|Planctomycetes	203682|Planctomycetes	P	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CH3_k127_7829976_9	1313301.AUGC01000009_gene1068	2.968e-58	212.0	COG0394@1|root,COG0394@2|Bacteria,4NE8C@976|Bacteroidetes	976|Bacteroidetes	T	protein tyrosine phosphatase	-	-	1.20.4.1,3.1.3.48	ko:K01104,ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	-
CH3_k127_7829976_0	886293.Sinac_3461	7.609e-224	707.0	COG3119@1|root,COG3119@2|Bacteria,2IXR4@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
CH3_k127_7829976_1	497964.CfE428DRAFT_4420	5.16e-217	685.0	COG3119@1|root,COG3119@2|Bacteria,46V0M@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Domain of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	DUF4994,Sulfatase
CH3_k127_7829976_6	886293.Sinac_3103	1.723e-83	287.0	COG1082@1|root,COG1082@2|Bacteria,2IZ3D@203682|Planctomycetes	203682|Planctomycetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CH3_k127_7829976_7	1403819.BATR01000118_gene4116	8.163e-76	265.0	COG1940@1|root,COG1940@2|Bacteria,46T0E@74201|Verrucomicrobia	74201|Verrucomicrobia	GK	PFAM ROK family protein	-	-	-	-	-	-	-	-	-	-	-	-	ROK
CH3_k127_7829976_4	1499967.BAYZ01000093_gene4011	3.472e-99	331.0	COG0673@1|root,COG0673@2|Bacteria,2NRE6@2323|unclassified Bacteria	2|Bacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	1.1.99.28	ko:K00118	-	-	-	-	ko00000,ko01000	-	-	-	GFO_IDH_MocA
CH3_k127_7842005_1	382464.ABSI01000011_gene2469	3.992e-182	578.0	COG0827@1|root,COG0827@2|Bacteria	2|Bacteria	L	DNA restriction-modification system	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_7842005_0	382464.ABSI01000011_gene2470	1.058e-203	642.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_13,Methyltransf_14,Methyltransf_23
CH3_k127_7842005_2	382464.ABSI01000011_gene2471	4.757e-162	516.0	COG0451@1|root,COG0451@2|Bacteria,46V8P@74201|Verrucomicrobia	74201|Verrucomicrobia	GM	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
CH3_k127_7842005_3	118163.Ple7327_1377	1.675e-128	415.0	COG1208@1|root,COG1208@2|Bacteria,1G00Y@1117|Cyanobacteria,3VIEN@52604|Pleurocapsales	1117|Cyanobacteria	JM	COGs COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)	-	-	2.7.7.33	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	-	R00956	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
CH3_k127_7842005_5	118161.KB235922_gene5204	1.207e-19	103.0	COG4767@1|root,COG4767@2|Bacteria,1G359@1117|Cyanobacteria,3VHTF@52604|Pleurocapsales	1117|Cyanobacteria	V	PFAM VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,VanZ
CH3_k127_7842005_4	247490.KSU1_C1702	4.913e-78	273.0	COG0438@1|root,COG0438@2|Bacteria,2IY70@203682|Planctomycetes	203682|Planctomycetes	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CH3_k127_7866552_0	497964.CfE428DRAFT_0210	1.501e-139	458.0	COG0624@1|root,COG0624@2|Bacteria,46UH8@74201|Verrucomicrobia	74201|Verrucomicrobia	E	peptidase dimerisation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
CH3_k127_7866552_1	497964.CfE428DRAFT_5484	2.788e-135	449.0	COG0323@1|root,COG0323@2|Bacteria,46SG5@74201|Verrucomicrobia	74201|Verrucomicrobia	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
CH3_k127_7882449_0	497964.CfE428DRAFT_2506	7.82e-194	608.0	COG0065@1|root,COG0065@2|Bacteria,46SUM@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
CH3_k127_7882449_1	344747.PM8797T_15161	9.255e-112	376.0	COG0673@1|root,COG0673@2|Bacteria,2IXE4@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CH3_k127_7882449_3	314230.DSM3645_26609	5.076e-56	204.0	COG2010@1|root,COG2133@1|root,COG3828@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,COG3828@2|Bacteria,2IYH1@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,Cytochrom_C,Cytochrome_CBB3,Laminin_G_3,ThuA
CH3_k127_7882449_2	452637.Oter_1501	4.344e-102	353.0	29YN3@1|root,30KHK@2|Bacteria	2|Bacteria	S	Putative ABC exporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_export
CH3_k127_7885157_2	452637.Oter_0906	4.253e-74	266.0	COG0664@1|root,COG0664@2|Bacteria,46VK1@74201|Verrucomicrobia,3K7W4@414999|Opitutae	74201|Verrucomicrobia	K	Crp Fnr family	-	-	-	ko:K21563	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CH3_k127_7885157_3	344747.PM8797T_28884	6.211e-59	216.0	COG0731@1|root,COG0731@2|Bacteria,2IXA2@203682|Planctomycetes	203682|Planctomycetes	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
CH3_k127_7885157_1	589865.DaAHT2_1112	1.8e-256	806.0	COG0427@1|root,COG1670@1|root,COG0427@2|Bacteria,COG1670@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria,2MI87@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Acetyl-CoA hydrolase transferase	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1,Acetyltransf_3
CH3_k127_7885157_0	589865.DaAHT2_1111	1.942e-263	829.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,42KZW@68525|delta/epsilon subdivisions,2WIQB@28221|Deltaproteobacteria,2MIWX@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM CoA-binding domain protein	-	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
CH3_k127_7885157_4	886293.Sinac_0541	2.196e-31	123.0	COG0546@1|root,COG0546@2|Bacteria,2IZVE@203682|Planctomycetes	203682|Planctomycetes	S	haloacid dehalogenase-like hydrolase	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
CH3_k127_7895012_8	1396418.BATQ01000110_gene4755	8.605e-38	161.0	COG0560@1|root,COG0560@2|Bacteria,46VDQ@74201|Verrucomicrobia,2ITM4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
CH3_k127_7895012_4	234267.Acid_1327	1.303e-81	291.0	COG0318@1|root,COG0318@2|Bacteria,3Y65U@57723|Acidobacteria	57723|Acidobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
CH3_k127_7895012_1	1123242.JH636434_gene4800	4.057e-121	404.0	COG2271@1|root,COG2271@2|Bacteria,2IZBA@203682|Planctomycetes	203682|Planctomycetes	G	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CH3_k127_7895012_5	234267.Acid_0687	1.907e-76	279.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,3Y6TZ@57723|Acidobacteria	2|Bacteria	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2
CH3_k127_7895012_10	1123319.AUBE01000006_gene3230	8.635e-26	118.0	COG5485@1|root,COG5485@2|Bacteria,2GJYB@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
CH3_k127_7895012_3	1123242.JH636435_gene944	3.417e-99	345.0	COG1520@1|root,COG1520@2|Bacteria,2IYRB@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CH3_k127_7895012_0	452637.Oter_1389	1.107e-157	539.0	COG0515@1|root,COG0515@2|Bacteria,46VB0@74201|Verrucomicrobia,3K8AK@414999|Opitutae	414999|Opitutae	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CH3_k127_7895012_7	1123508.JH636439_gene990	2.819e-51	187.0	COG1595@1|root,COG1595@2|Bacteria,2IZ8A@203682|Planctomycetes	203682|Planctomycetes	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
CH3_k127_7895012_2	1226994.AMZB01000119_gene3308	1.344e-116	395.0	COG2271@1|root,COG2271@2|Bacteria,1MWYR@1224|Proteobacteria,1RR7T@1236|Gammaproteobacteria,1YD63@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CH3_k127_7895012_6	1089550.ATTH01000001_gene2299	1.239e-72	253.0	COG1028@1|root,COG1028@2|Bacteria,4NGQY@976|Bacteroidetes	976|Bacteroidetes	IQ	Short-chain dehydrogenase reductase sdr	-	-	1.1.1.401	ko:K21883	ko00051,ko01120,map00051,map01120	-	R11339	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
CH3_k127_7895012_11	368407.Memar_0224	2.186e-07	59.0	COG2768@1|root,arCOG02448@2157|Archaea,2XW30@28890|Euryarchaeota,2N9AE@224756|Methanomicrobia	224756|Methanomicrobia	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	ko:K07138	-	-	-	-	ko00000	-	-	-	DUF362,Fer4
CH3_k127_7895012_9	1303518.CCALI_02368	2.243e-29	121.0	COG0518@1|root,COG0518@2|Bacteria	2|Bacteria	F	GMP synthase (glutamine-hydrolyzing) activity	guaA_1	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
CH3_k127_7896852_8	497964.CfE428DRAFT_5287	1.76e-21	99.0	COG0848@1|root,COG0848@2|Bacteria,46T4F@74201|Verrucomicrobia	74201|Verrucomicrobia	U	PFAM Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
CH3_k127_7896852_6	497964.CfE428DRAFT_5288	3.26e-45	172.0	COG0811@1|root,COG0811@2|Bacteria,46V4I@74201|Verrucomicrobia	74201|Verrucomicrobia	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
CH3_k127_7896852_2	518766.Rmar_2306	2.411e-89	301.0	COG0047@1|root,COG0047@2|Bacteria,4NFER@976|Bacteroidetes,1FIWZ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
CH3_k127_7896852_9	1411123.JQNH01000001_gene19	5.086e-18	87.0	COG1828@1|root,COG1828@2|Bacteria,1N83G@1224|Proteobacteria,2UF7S@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
CH3_k127_7896852_4	857087.Metme_4292	5.798e-76	269.0	COG2370@1|root,COG2370@2|Bacteria,1MV6Z@1224|Proteobacteria,1RNIU@1236|Gammaproteobacteria,1XH04@135618|Methylococcales	1236|Gammaproteobacteria	O	HupE / UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ_2
CH3_k127_7896852_1	452637.Oter_1491	3.191e-107	364.0	COG3014@1|root,COG3014@2|Bacteria	2|Bacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CH3_k127_7896852_5	1123508.JH636451_gene5878	2.476e-67	240.0	2DWSV@1|root,341QK@2|Bacteria,2J4FR@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_7896852_3	452637.Oter_1490	3.599e-85	287.0	COG3417@1|root,COG3417@2|Bacteria	2|Bacteria	M	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)	-	-	-	ko:K07337	-	-	-	-	ko00000	-	-	-	LpoB
CH3_k127_7896852_0	497964.CfE428DRAFT_4932	2.666e-130	420.0	COG0107@1|root,COG0107@2|Bacteria,46S6V@74201|Verrucomicrobia	74201|Verrucomicrobia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
CH3_k127_7953224_0	1379698.RBG1_1C00001G0996	3.711e-85	292.0	COG0463@1|root,COG0463@2|Bacteria,2NS3Y@2323|unclassified Bacteria	2|Bacteria	M	Glycosyltransferase like family 2	dpm1	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
CH3_k127_7953224_2	742725.HMPREF9450_02179	1.219e-34	141.0	COG1225@1|root,COG1225@2|Bacteria,4NNGK@976|Bacteroidetes,2FNTB@200643|Bacteroidia,22VB5@171550|Rikenellaceae	976|Bacteroidetes	O	Redoxin	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
CH3_k127_7953224_3	985053.VMUT_0013	2.679e-15	81.0	COG5550@1|root,arCOG03744@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_7953224_1	316274.Haur_0795	1.201e-62	232.0	COG0318@1|root,COG0318@2|Bacteria	2|Bacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,LuxE
CH3_k127_7968511_3	1123508.JH636443_gene4582	1.005e-64	235.0	COG1721@1|root,COG1721@2|Bacteria,2IY59@203682|Planctomycetes	203682|Planctomycetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CH3_k127_7968511_2	1384056.N787_01780	1.354e-68	239.0	2AP2K@1|root,31E40@2|Bacteria,1N3BH@1224|Proteobacteria,1STBY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_7968511_1	1173028.ANKO01000017_gene232	2.576e-90	312.0	COG0378@1|root,COG0378@2|Bacteria,1G2X6@1117|Cyanobacteria,1H8P3@1150|Oscillatoriales	1117|Cyanobacteria	KO	Ni2 binding GTPase involved in regulation of expression and maturation of urease and hydrogenase	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
CH3_k127_7968511_4	1173027.Mic7113_3070	3.992e-31	126.0	COG0375@1|root,COG0375@2|Bacteria,1G89Y@1117|Cyanobacteria,1HCJX@1150|Oscillatoriales	1117|Cyanobacteria	S	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
CH3_k127_7968511_0	272134.KB731324_gene5867	7.644e-217	691.0	COG0068@1|root,COG0068@2|Bacteria,1G063@1117|Cyanobacteria,1H71F@1150|Oscillatoriales	1117|Cyanobacteria	O	Belongs to the carbamoyltransferase HypF family	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
CH3_k127_7985221_4	635013.TherJR_2042	1.256e-24	111.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,24HHW@186801|Clostridia,261SF@186807|Peptococcaceae	186801|Clostridia	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
CH3_k127_7985221_3	497964.CfE428DRAFT_6522	5.808e-38	153.0	COG2045@1|root,COG2045@2|Bacteria	2|Bacteria	H	2-phosphosulfolactate phosphatase activity	comB	GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545	3.1.3.71	ko:K05979	ko00680,ko01120,map00680,map01120	M00358	R05789	RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	2-ph_phosp
CH3_k127_7985221_1	497964.CfE428DRAFT_5454	5.1e-64	233.0	COG0122@1|root,COG0122@2|Bacteria,46SVK@74201|Verrucomicrobia	74201|Verrucomicrobia	L	8-oxoguanine DNA glycosylase, N-terminal domain	alkA	-	4.2.99.18	ko:K03660	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD,OGG_N
CH3_k127_7985221_2	1396141.BATP01000057_gene2980	6.208e-56	201.0	COG0503@1|root,COG0503@2|Bacteria,46SV8@74201|Verrucomicrobia,2IUHK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Phosphoribosyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
CH3_k127_7985221_0	497964.CfE428DRAFT_4839	3.612e-115	378.0	COG0568@1|root,COG0568@2|Bacteria,46SJ8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
CH3_k127_7991166_9	497964.CfE428DRAFT_3654	2.55e-35	143.0	COG0576@1|root,COG0576@2|Bacteria,46T79@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
CH3_k127_7991166_2	382464.ABSI01000010_gene3750	1.601e-139	452.0	COG0484@1|root,COG0484@2|Bacteria,46TKC@74201|Verrucomicrobia,2ITUR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
CH3_k127_7991166_5	497964.CfE428DRAFT_3657	1.359e-65	232.0	COG1385@1|root,COG1385@2|Bacteria,46SZQ@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	-	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
CH3_k127_7991166_6	1396418.BATQ01000014_gene4333	1.432e-58	218.0	COG1565@1|root,COG1565@2|Bacteria,46T7F@74201|Verrucomicrobia,2IU90@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
CH3_k127_7991166_3	1304888.ATWF01000001_gene1852	1.966e-128	420.0	COG2805@1|root,COG2805@2|Bacteria,2GF8B@200930|Deferribacteres	200930|Deferribacteres	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
CH3_k127_7991166_0	56780.SYN_00126	1.681e-157	505.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WJ4Z@28221|Deltaproteobacteria,2MR4Y@213462|Syntrophobacterales	28221|Deltaproteobacteria	NU	Type IV secretion-system coupling protein DNA-binding domain	pilT1	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
CH3_k127_7991166_10	497964.CfE428DRAFT_5639	1.367e-12	74.0	COG0745@1|root,COG0745@2|Bacteria	497964.CfE428DRAFT_5639|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_7991166_4	667014.Thein_0763	1.04e-74	259.0	COG1189@1|root,COG1189@2|Bacteria,2GGSK@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	FtsJ-like methyltransferase	-	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
CH3_k127_7991166_7	1123070.KB899253_gene998	6.359e-54	201.0	COG0061@1|root,COG0061@2|Bacteria,46SUQ@74201|Verrucomicrobia,2IUD8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	CTP_transf_like,NAD_kinase
CH3_k127_7991166_8	1121472.AQWN01000011_gene1202	1.267e-53	203.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia,263U1@186807|Peptococcaceae	186801|Clostridia	K	Periplasmic binding protein-like domain	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
CH3_k127_7991166_11	1403819.BATR01000042_gene1260	2.485e-10	67.0	COG3952@1|root,COG3952@2|Bacteria,46T9Z@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Lipid A Biosynthesis N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	LAB_N,T2SSG
CH3_k127_7991166_1	794903.OPIT5_16815	3.92e-150	479.0	COG1048@1|root,COG1048@2|Bacteria,46SFS@74201|Verrucomicrobia,3K7UQ@414999|Opitutae	414999|Opitutae	C	Aconitase family (aconitate hydratase)	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
CH3_k127_7998931_0	521674.Plim_1473	9.093e-72	250.0	COG0515@1|root,COG0515@2|Bacteria,2J50A@203682|Planctomycetes	203682|Planctomycetes	KLT	PFAM Serine threonine protein kinase-related	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,dCache_1
CH3_k127_7998931_1	926550.CLDAP_04870	2.76e-61	233.0	COG2133@1|root,COG2133@2|Bacteria,2G62S@200795|Chloroflexi	200795|Chloroflexi	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
CH3_k127_8035232_0	1121920.AUAU01000024_gene2382	4.729e-93	320.0	COG3303@1|root,COG4733@1|root,COG3303@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	4.2.2.1	ko:K01727	-	-	-	-	ko00000,ko01000	-	PL8	-	Big_2,DUF285,HYR,Laminin_G_3,Lyase_8,Lyase_8_C,Lyase_8_N,Paired_CXXCH_1,SLH,fn3
CH3_k127_8035232_1	1121920.AUAU01000024_gene2384	5.862e-77	279.0	COG1333@1|root,COG1333@2|Bacteria	2|Bacteria	O	cytochrome c biogenesis protein	resB	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
CH3_k127_8035972_2	1120792.JAFV01000001_gene328	1.981e-08	64.0	2C0VP@1|root,32ZQ9@2|Bacteria,1NENB@1224|Proteobacteria,2UGGI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_8035972_1	411490.ANACAC_00802	1.16e-20	98.0	2DVY7@1|root,32V0C@2|Bacteria,1VAXX@1239|Firmicutes,24P61@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_8035972_3	679190.HMPREF0650_1053	1.851e-06	52.0	2DQYP@1|root,339EX@2|Bacteria,4NWWZ@976|Bacteroidetes,2FT6P@200643|Bacteroidia	976|Bacteroidetes	S	DNA binding domain, excisionase family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
CH3_k127_8045603_1	234267.Acid_2132	8.534e-61	216.0	COG1028@1|root,COG1028@2|Bacteria,3Y7BE@57723|Acidobacteria	57723|Acidobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CH3_k127_8045603_4	1242864.D187_001577	2.176e-05	57.0	COG3420@1|root,COG3420@2|Bacteria,1R5QH@1224|Proteobacteria	1224|Proteobacteria	P	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
CH3_k127_8045603_0	1242864.D187_008109	1.035e-123	406.0	COG0388@1|root,COG0388@2|Bacteria,1MXG5@1224|Proteobacteria,42PV7@68525|delta/epsilon subdivisions,2WKXE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
CH3_k127_8045603_3	640512.BC1003_5144	4.084e-07	53.0	COG1064@1|root,COG1064@2|Bacteria,1P0UC@1224|Proteobacteria,2VPCZ@28216|Betaproteobacteria,1KGVQ@119060|Burkholderiaceae	28216|Betaproteobacteria	C	alcohol dehydrogenase	-	-	1.1.1.1	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CH3_k127_8045603_5	395961.Cyan7425_5164	0.0002065	44.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
CH3_k127_8045603_2	234267.Acid_6639	3.886e-51	190.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
CH3_k127_8050796_0	1121335.Clst_0783	1.934e-167	532.0	COG0524@1|root,COG0524@2|Bacteria,1TRRY@1239|Firmicutes,248Y3@186801|Clostridia,3WHKM@541000|Ruminococcaceae	186801|Clostridia	G	Kinase, PfkB family	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
CH3_k127_8050796_1	1123508.JH636442_gene3883	1.735e-21	108.0	COG3779@1|root,COG3779@2|Bacteria,2J1PD@203682|Planctomycetes	203682|Planctomycetes	S	Uncharacterized protein conserved in bacteria (DUF2314)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2314
CH3_k127_8079030_3	204669.Acid345_2776	1.406e-60	216.0	COG1943@1|root,COG1943@2|Bacteria,3Y81S@57723|Acidobacteria,2JN69@204432|Acidobacteriia	204432|Acidobacteriia	L	DNA binding domain with preference for A/T rich regions	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
CH3_k127_8079030_2	234267.Acid_2016	1.513e-71	247.0	COG3344@1|root,COG3344@2|Bacteria,3Y46K@57723|Acidobacteria	57723|Acidobacteria	L	PFAM RNA-directed DNA polymerase (Reverse transcriptase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,RVT_1,RVT_N
CH3_k127_8079030_0	237609.PSAKL28_31720	1.024e-309	966.0	COG1961@1|root,COG1961@2|Bacteria,1MVIE@1224|Proteobacteria,1RZMQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
CH3_k127_8079030_1	234267.Acid_2016	1.537e-99	332.0	COG3344@1|root,COG3344@2|Bacteria,3Y46K@57723|Acidobacteria	57723|Acidobacteria	L	PFAM RNA-directed DNA polymerase (Reverse transcriptase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,RVT_1,RVT_N
CH3_k127_8079030_4	234267.Acid_7761	1.289e-06	51.0	2FHZ5@1|root,349S3@2|Bacteria,3Y8GI@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_809727_2	313628.LNTAR_07769	7.923e-15	86.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
CH3_k127_809727_0	497964.CfE428DRAFT_5370	1.872e-131	425.0	COG2255@1|root,COG2255@2|Bacteria,46SDS@74201|Verrucomicrobia	74201|Verrucomicrobia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
CH3_k127_8115569_1	1499967.BAYZ01000045_gene2649	3.869e-111	370.0	COG0498@1|root,COG0498@2|Bacteria,2NQNZ@2323|unclassified Bacteria	2|Bacteria	E	Threonine synthase N terminus	thrC	GO:0003674,GO:0003824,GO:0004795,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	iLF82_1304.LF82_2261,iNRG857_1313.NRG857_00025	PALP,Thr_synth_N
CH3_k127_8115569_0	452637.Oter_2235	4.139e-180	574.0	COG0460@1|root,COG0460@2|Bacteria,46TFC@74201|Verrucomicrobia,3K7MC@414999|Opitutae	414999|Opitutae	E	homoserine dehydrogenase	-	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
CH3_k127_8144994_0	1423321.AS29_02765	8.247e-12	76.0	COG4974@1|root,COG4974@2|Bacteria,1V0XC@1239|Firmicutes,4HGMY@91061|Bacilli,1ZCAZ@1386|Bacillus	91061|Bacilli	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
CH3_k127_8151210_4	1379698.RBG1_1C00001G1779	1.864e-46	172.0	COG0714@1|root,COG0714@2|Bacteria,2NNMQ@2323|unclassified Bacteria	2|Bacteria	S	ATPase associated with various cellular	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CH3_k127_8151210_3	1396418.BATQ01000085_gene1110	3.622e-66	239.0	COG0196@1|root,COG0196@2|Bacteria,46SZ6@74201|Verrucomicrobia,2IU48@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Riboflavin kinase	-	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
CH3_k127_8151210_1	452637.Oter_2817	4.277e-80	273.0	COG0130@1|root,COG0130@2|Bacteria,46SJR@74201|Verrucomicrobia,3K75I@414999|Opitutae	414999|Opitutae	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C_2,TruB_N
CH3_k127_8151210_2	497964.CfE428DRAFT_1792	1.07e-67	242.0	COG0618@1|root,COG0618@2|Bacteria,46T03@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM phosphoesterase RecJ domain protein	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
CH3_k127_8151210_5	32057.KB217478_gene5529	1.289e-12	73.0	COG0858@1|root,COG0858@2|Bacteria,1G6JJ@1117|Cyanobacteria,1HNRI@1161|Nostocales	1117|Cyanobacteria	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
CH3_k127_8151210_0	1120971.AUCA01000011_gene2929	3.689e-179	585.0	COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,4HA8S@91061|Bacilli,2787Q@186823|Alicyclobacillaceae	91061|Bacilli	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
CH3_k127_8167979_1	497964.CfE428DRAFT_3506	2.356e-38	152.0	COG4409@1|root,COG4409@2|Bacteria,46SHF@74201|Verrucomicrobia	74201|Verrucomicrobia	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
CH3_k127_8167979_0	509635.N824_16950	2.021e-70	262.0	28MSZ@1|root,2ZB1A@2|Bacteria,4NHVN@976|Bacteroidetes	976|Bacteroidetes	S	GxGYxY sequence motif in domain of unknown function N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	GxGYxYP_C,GxGYxYP_N
CH3_k127_8167979_2	794903.OPIT5_09305	2.543e-11	75.0	COG2165@1|root,COG2165@2|Bacteria,46YH2@74201|Verrucomicrobia,3K9K1@414999|Opitutae	414999|Opitutae	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_8179383_4	693746.OBV_13620	4.518e-46	169.0	COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,247T0@186801|Clostridia,2N696@216572|Oscillospiraceae	186801|Clostridia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
CH3_k127_8179383_1	1123242.JH636435_gene1109	4.899e-141	456.0	COG3386@1|root,COG3386@2|Bacteria,2IXZT@203682|Planctomycetes	203682|Planctomycetes	G	gluconolactonase	-	-	-	-	-	-	-	-	-	-	-	-	SGL
CH3_k127_8179383_5	794903.OPIT5_02620	1.119e-35	140.0	COG0292@1|root,COG0292@2|Bacteria,46SZW@74201|Verrucomicrobia,3K87I@414999|Opitutae	414999|Opitutae	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
CH3_k127_8179383_6	349741.Amuc_1556	1.41e-12	72.0	COG0291@1|root,COG0291@2|Bacteria,46TCI@74201|Verrucomicrobia,2IUW5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal protein L35	-	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
CH3_k127_8179383_3	886293.Sinac_7310	4.135e-117	384.0	COG1413@1|root,COG1413@2|Bacteria,2IYWU@203682|Planctomycetes	203682|Planctomycetes	C	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CH3_k127_8179383_0	234267.Acid_3246	2.245e-183	587.0	COG0673@1|root,COG0673@2|Bacteria,3Y76D@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CH3_k127_8179383_2	497964.CfE428DRAFT_4366	6.276e-126	417.0	COG1520@1|root,COG1520@2|Bacteria,46TRS@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CH3_k127_8179383_8	1173023.KE650771_gene2595	1.893e-05	50.0	COG2303@1|root,COG2303@2|Bacteria,1G2DQ@1117|Cyanobacteria,1JHUA@1189|Stigonemataceae	1117|Cyanobacteria	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
CH3_k127_8179383_7	671065.MetMK1DRAFT_00016260	5.11e-09	68.0	COG0666@1|root,arCOG04004@2157|Archaea,2XS0N@28889|Crenarchaeota	28889|Crenarchaeota	S	ankyrin repeats	-	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank_2,Ank_4
CH3_k127_8179383_9	378753.KRH_07290	0.0003759	47.0	COG2801@1|root,COG2801@2|Bacteria,2GJ3V@201174|Actinobacteria,1WA7Y@1268|Micrococcaceae	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,LZ_Tnp_IS481,rve,rve_3
CH3_k127_8186297_0	497964.CfE428DRAFT_6352	0.0	1080.0	COG1061@1|root,COG2852@1|root,COG4951@1|root,COG1061@2|Bacteria,COG2852@2|Bacteria,COG4951@2|Bacteria,46UU5@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	DUF559,ResIII
CH3_k127_8186297_1	13035.Dacsa_2950	8.251e-121	394.0	COG0863@1|root,COG0863@2|Bacteria	2|Bacteria	L	N-4 methylation of cytosine	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase,RE_Eco29kI
CH3_k127_8186297_2	497964.CfE428DRAFT_3301	6.652e-75	252.0	COG0422@1|root,COG0422@2|Bacteria,46S5R@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
CH3_k127_8187896_0	572477.Alvin_0546	3.989e-260	837.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,1RQ0G@1236|Gammaproteobacteria,1WXEX@135613|Chromatiales	135613|Chromatiales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
CH3_k127_8187896_1	743721.Psesu_2270	9.924e-10	70.0	COG3746@1|root,COG3746@2|Bacteria,1R9AP@1224|Proteobacteria,1RS2N@1236|Gammaproteobacteria,1X2Z1@135614|Xanthomonadales	135614|Xanthomonadales	P	Phosphate-selective porin O and P	-	-	-	ko:K07221	-	-	-	-	ko00000,ko02000	1.B.5.1	-	-	Porin_O_P
CH3_k127_8194523_7	926556.Echvi_2883	4.517e-05	49.0	COG2217@1|root,COG2608@1|root,COG2217@2|Bacteria,COG2608@2|Bacteria,4NEI1@976|Bacteroidetes,47N4X@768503|Cytophagia	976|Bacteroidetes	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	ccoI	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
CH3_k127_8194523_5	1313301.AUGC01000014_gene2496	5.602e-08	57.0	COG3197@1|root,COG3197@2|Bacteria	2|Bacteria	P	Cytochrome oxidase maturation protein	ccoS	-	-	-	-	-	-	-	-	-	-	-	FixS
CH3_k127_8194523_0	1191523.MROS_1513	0.0	1073.0	COG2993@1|root,COG3278@1|root,COG2993@2|Bacteria,COG3278@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor	ccoO	GO:0003674,GO:0003824,GO:0004129,GO:0005215,GO:0005488,GO:0005506,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008144,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0015975,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016675,GO:0016676,GO:0016705,GO:0017144,GO:0019411,GO:0019637,GO:0019646,GO:0019693,GO:0019825,GO:0020037,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0034641,GO:0036094,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045154,GO:0045333,GO:0046034,GO:0046483,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0070069,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:1901135,GO:1901360,GO:1901363,GO:1901564,GO:1902600	1.9.3.1	ko:K00404,ko:K00405,ko:K15862	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	iIT341.HP0144,iIT341.HP0145	COX1,FixO
CH3_k127_8194523_3	1191523.MROS_1515	1.13e-45	171.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
CH3_k127_8194523_1	1121930.AQXG01000002_gene2269	9.657e-161	520.0	COG0348@1|root,COG0348@2|Bacteria,4NFDN@976|Bacteroidetes,1IP29@117747|Sphingobacteriia	976|Bacteroidetes	C	cytochrome c oxidase	ccoG	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
CH3_k127_8194523_4	1356852.N008_20380	4.096e-24	109.0	COG3198@1|root,COG3198@2|Bacteria,4PPZ3@976|Bacteroidetes,47RV1@768503|Cytophagia	976|Bacteroidetes	S	FixH	ccoH	-	-	ko:K09926	-	-	-	-	ko00000	-	-	-	FixH
CH3_k127_8194523_2	313606.M23134_03514	7.81e-52	191.0	COG2836@1|root,COG2836@2|Bacteria,4NF84@976|Bacteroidetes,47QDS@768503|Cytophagia	976|Bacteroidetes	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2
CH3_k127_8196912_3	926556.Echvi_2305	9.712e-107	348.0	COG1770@1|root,COG1770@2|Bacteria,4NEQS@976|Bacteroidetes,47KWW@768503|Cytophagia	976|Bacteroidetes	E	PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain	ptrB	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
CH3_k127_8196912_4	1123242.JH636435_gene944	2.073e-90	316.0	COG1520@1|root,COG1520@2|Bacteria,2IYRB@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CH3_k127_8196912_1	1234364.AMSF01000079_gene1843	1.435e-108	368.0	COG1680@1|root,COG1680@2|Bacteria,1RBDE@1224|Proteobacteria,1RYDP@1236|Gammaproteobacteria,1X4U9@135614|Xanthomonadales	135614|Xanthomonadales	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CH3_k127_8196912_8	452637.Oter_1389	3.231e-44	165.0	COG0515@1|root,COG0515@2|Bacteria,46VB0@74201|Verrucomicrobia,3K8AK@414999|Opitutae	414999|Opitutae	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CH3_k127_8196912_13	1026882.MAMP_01168	2.098e-07	62.0	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,1RQIX@1236|Gammaproteobacteria,460M7@72273|Thiotrichales	72273|Thiotrichales	NU	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_8
CH3_k127_8196912_12	1396141.BATP01000060_gene4647	4.788e-09	59.0	COG0515@1|root,COG0515@2|Bacteria,46UAE@74201|Verrucomicrobia,2IV44@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_12,WD40
CH3_k127_8196912_5	1296416.JACB01000027_gene4076	6.395e-67	239.0	2BWKA@1|root,32QZQ@2|Bacteria,4P163@976|Bacteroidetes,1I86M@117743|Flavobacteriia	976|Bacteroidetes	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
CH3_k127_8196912_9	237368.SCABRO_03851	4.404e-17	91.0	COG2165@1|root,COG2165@2|Bacteria,2J0Q6@203682|Planctomycetes	203682|Planctomycetes	U	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CH3_k127_8196912_2	1123242.JH636435_gene944	8.934e-108	368.0	COG1520@1|root,COG1520@2|Bacteria,2IYRB@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CH3_k127_8196912_6	497964.CfE428DRAFT_0215	1.901e-58	213.0	COG1716@1|root,COG2114@1|root,COG1716@2|Bacteria,COG2114@2|Bacteria	2|Bacteria	T	Pfam Adenylate and Guanylate cyclase catalytic domain	cya1	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,Guanylate_cyc
CH3_k127_8196912_10	1303518.CCALI_02394	1.695e-15	87.0	COG4537@1|root,COG4537@2|Bacteria	2|Bacteria	U	Required for transformation and DNA binding	comGC	GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944	-	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	M00331,M00429	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
CH3_k127_8196912_11	1303518.CCALI_00378	7.723e-15	84.0	COG4969@1|root,COG4969@2|Bacteria	2|Bacteria	NU	cell adhesion	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,SBP_bac_10
CH3_k127_8196912_0	497964.CfE428DRAFT_4557	3.802e-191	607.0	COG2133@1|root,COG2133@2|Bacteria,46U0G@74201|Verrucomicrobia	74201|Verrucomicrobia	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_8196912_7	756272.Plabr_1201	3.324e-52	203.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG3828@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,COG3828@2|Bacteria,2IXKV@203682|Planctomycetes	203682|Planctomycetes	C	Membrane-bound dehydrogenase domain	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DUF1080,GSDH,NPCBM,ThuA
CH3_k127_8196912_14	545697.HMPREF0216_03070	9.546e-07	61.0	COG1196@1|root,COG1538@1|root,COG3250@1|root,COG1196@2|Bacteria,COG1538@2|Bacteria,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,248H7@186801|Clostridia,36F2A@31979|Clostridiaceae	186801|Clostridia	G	family 2, TIM barrel	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,FIVAR,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Laminin_G_3,NPCBM
CH3_k127_8207080_2	102125.Xen7305DRAFT_00020060	4.089e-26	126.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CW_binding_1,VCBS
CH3_k127_8207080_1	107636.JQNK01000008_gene4403	1.54e-46	185.0	COG3039@1|root,COG3039@2|Bacteria,1MVDK@1224|Proteobacteria,2U401@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase	-	-	-	ko:K07481	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DUF772
CH3_k127_8207080_0	794903.OPIT5_07190	3.668e-182	589.0	COG0745@1|root,COG5002@1|root,COG0745@2|Bacteria,COG5002@2|Bacteria,46URZ@74201|Verrucomicrobia,3K946@414999|Opitutae	414999|Opitutae	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
CH3_k127_8207722_3	452637.Oter_3992	6.318e-19	90.0	COG1898@1|root,COG1898@2|Bacteria,46X3Z@74201|Verrucomicrobia,3K9US@414999|Opitutae	414999|Opitutae	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
CH3_k127_8207722_0	216596.RL0795	5.567e-128	415.0	COG1209@1|root,COG1209@2|Bacteria,1MU0X@1224|Proteobacteria,2TQPI@28211|Alphaproteobacteria,4BB7T@82115|Rhizobiaceae	28211|Alphaproteobacteria	M	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
CH3_k127_8207722_2	794903.OPIT5_19905	4.469e-26	115.0	COG0250@1|root,COG0250@2|Bacteria,46XU3@74201|Verrucomicrobia,3K844@414999|Opitutae	414999|Opitutae	K	Transcription termination factor nusG	-	-	-	-	-	-	-	-	-	-	-	-	NusG
CH3_k127_8207722_5	1453505.JASY01000013_gene4343	0.0003596	49.0	2CIT3@1|root,32Y0C@2|Bacteria,4NUWR@976|Bacteroidetes,1I533@117743|Flavobacteriia,2NWGN@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4890
CH3_k127_8207722_1	452637.Oter_2449	3.391e-66	232.0	COG0652@1|root,COG0652@2|Bacteria,46VEN@74201|Verrucomicrobia,3K7Y9@414999|Opitutae	414999|Opitutae	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
CH3_k127_8221901_0	1288963.ADIS_4374	2.574e-226	725.0	28MHM@1|root,2ZAUH@2|Bacteria,4NKMG@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_8221901_1	867900.Celly_1905	2.249e-07	59.0	COG1361@1|root,COG2931@1|root,COG1361@2|Bacteria,COG2931@2|Bacteria,4NG16@976|Bacteroidetes,1HY10@117743|Flavobacteriia	976|Bacteroidetes	M	C-terminal domain of CHU protein family	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Calx-beta,DUF11,SdrD_B
CH3_k127_8227742_0	1120950.KB892756_gene6635	6.164e-73	279.0	29XIB@1|root,30J98@2|Bacteria,2H3UJ@201174|Actinobacteria	201174|Actinobacteria	S	Heparinase II/III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III
CH3_k127_8227742_2	1423321.AS29_04220	2.777e-49	203.0	COG1073@1|root,COG1073@2|Bacteria,1UKWE@1239|Firmicutes,4ITSD@91061|Bacilli	91061|Bacilli	S	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
CH3_k127_8227742_1	545694.TREPR_0418	3.315e-53	202.0	COG1262@1|root,COG1262@2|Bacteria,2J5Y8@203691|Spirochaetes	203691|Spirochaetes	C	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Flavodoxin_4
CH3_k127_8232322_10	234267.Acid_2658	1.411e-62	224.0	COG4409@1|root,COG4692@1|root,COG4409@2|Bacteria,COG4692@2|Bacteria	2|Bacteria	G	BNR repeat-like domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	BNR_2
CH3_k127_8232322_3	1453501.JELR01000001_gene2132	4.057e-146	485.0	COG1409@1|root,COG1409@2|Bacteria,1NS3S@1224|Proteobacteria,1RR8K@1236|Gammaproteobacteria,466XF@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
CH3_k127_8232322_19	1121272.KB903251_gene659	0.000541	51.0	COG3866@1|root,COG4733@1|root,COG3866@2|Bacteria,COG4733@2|Bacteria,2GNKW@201174|Actinobacteria,4DAGW@85008|Micromonosporales	201174|Actinobacteria	G	Amb_all	-	-	4.2.2.2	ko:K01728	ko00040,ko02024,map00040,map02024	-	R02361,R06240	RC00049,RC00705	ko00000,ko00001,ko01000	-	-	-	DUF1080,Pec_lyase_C
CH3_k127_8232322_0	1267535.KB906767_gene2459	4.389e-247	784.0	COG1874@1|root,COG1874@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	3.2.1.23,3.2.1.4	ko:K01179,ko:K01190,ko:K12308	ko00052,ko00500,ko00511,ko00600,ko01100,map00052,map00500,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114,R06200,R11307,R11308	RC00049,RC00452	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_6,DUF4832,DUF4978,FIVAR,Glyco_hydro_42,Glyco_hydro_42M
CH3_k127_8232322_1	583355.Caka_3109	5.407e-217	738.0	COG2312@1|root,COG3507@1|root,COG2312@2|Bacteria,COG3507@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 43 family	-	-	1.16.3.3	ko:K22350	-	-	-	-	ko00000,ko01000	-	-	-	Big_2,Big_4,CBM_6,DUF1080,DUF1349,Erythro_esteras,GSDH,Glyco_hydro_43,LTD,Laminin_G_3,PKD,SLH
CH3_k127_8232322_13	573061.Clocel_1966	1.959e-39	172.0	COG1409@1|root,COG1409@2|Bacteria,1VTEB@1239|Firmicutes,24E3Z@186801|Clostridia,36GZ8@31979|Clostridiaceae	186801|Clostridia	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
CH3_k127_8232322_18	1396141.BATP01000007_gene5656	5.584e-07	64.0	COG2312@1|root,COG3506@1|root,COG2312@2|Bacteria,COG3506@2|Bacteria,46SQ1@74201|Verrucomicrobia,2IV3A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	N	Erythromycin esterase	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_8232322_17	1303518.CCALI_02038	6.815e-16	87.0	COG4969@1|root,COG4969@2|Bacteria	2|Bacteria	NU	cell adhesion	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,SBP_bac_10
CH3_k127_8232322_4	886293.Sinac_4751	4.057e-145	477.0	COG0584@1|root,COG0584@2|Bacteria,2IXVA@203682|Planctomycetes	203682|Planctomycetes	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
CH3_k127_8232322_14	1270193.JARP01000004_gene1522	2.929e-27	126.0	COG0823@1|root,COG0823@2|Bacteria,4NFQ0@976|Bacteroidetes,1I7I9@117743|Flavobacteriia,2NSYV@237|Flavobacterium	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	4.2.2.6	ko:K01730	ko00040,map00040	-	R04382	RC02124,RC02427	ko00000,ko00001,ko01000	-	-	-	PD40,Pectate_lyase22
CH3_k127_8232322_11	530564.Psta_3954	6.294e-61	221.0	COG4785@1|root,COG4785@2|Bacteria,2IZYN@203682|Planctomycetes	203682|Planctomycetes	S	May be involved in cell division	-	-	-	ko:K05803	-	-	-	-	ko00000	-	-	-	TPR_16
CH3_k127_8232322_6	595460.RRSWK_04460	4.307e-104	346.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
CH3_k127_8232322_7	314230.DSM3645_25492	5.007e-96	329.0	COG0673@1|root,COG0673@2|Bacteria,2IXRR@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CH3_k127_8232322_2	1123508.JH636450_gene7203	9.447e-206	664.0	COG3356@1|root,COG3356@2|Bacteria,2IXDY@203682|Planctomycetes	203682|Planctomycetes	G	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk,Laminin_G_3
CH3_k127_8232322_12	1536773.R70331_08785	8.813e-44	176.0	COG1520@1|root,COG1520@2|Bacteria,1UIHU@1239|Firmicutes,4ISIB@91061|Bacilli,2773B@186822|Paenibacillaceae	91061|Bacilli	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_8232322_15	1353531.AZNX01000014_gene3221	5.287e-24	116.0	COG2159@1|root,COG2159@2|Bacteria,1ND2I@1224|Proteobacteria,2UIP1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CH3_k127_8232322_5	1210884.HG799471_gene14593	5.195e-141	466.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,2IXJQ@203682|Planctomycetes	203682|Planctomycetes	C	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk,Cytochrom_C
CH3_k127_8232322_8	1142394.PSMK_12790	1.27e-82	286.0	COG0673@1|root,COG0673@2|Bacteria,2IY6G@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CH3_k127_8232322_9	1142394.PSMK_13110	1.018e-72	256.0	COG1082@1|root,COG1082@2|Bacteria,2IXZ6@203682|Planctomycetes	203682|Planctomycetes	G	isomerase	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CH3_k127_8232322_16	1278073.MYSTI_02879	5.712e-19	86.0	28H8R@1|root,2Z7KJ@2|Bacteria,1Q390@1224|Proteobacteria,43905@68525|delta/epsilon subdivisions,2X457@28221|Deltaproteobacteria,2YYAC@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_8309007_2	1047013.AQSP01000097_gene1961	4.129e-31	132.0	COG4122@1|root,COG4122@2|Bacteria,2NPV6@2323|unclassified Bacteria	2|Bacteria	S	Methyltransferase domain	mdmC	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24,Methyltransf_3
CH3_k127_8309007_0	497964.CfE428DRAFT_1708	1.279e-168	539.0	COG0527@1|root,COG0527@2|Bacteria,46SIS@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Amino acid kinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
CH3_k127_8309007_1	903818.KI912268_gene822	1e-75	261.0	COG0498@1|root,COG0498@2|Bacteria	2|Bacteria	E	threonine synthase activity	thrC	GO:0003674,GO:0003824,GO:0004795,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	iLF82_1304.LF82_2261,iNRG857_1313.NRG857_00025	PALP,Thr_synth_N
CH3_k127_8313799_1	1396418.BATQ01000147_gene3609	6.445e-191	615.0	COG1520@1|root,COG1520@2|Bacteria,46UUP@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CH3_k127_8313799_0	497964.CfE428DRAFT_5031	1.622e-224	710.0	COG1520@1|root,COG1520@2|Bacteria,46U89@74201|Verrucomicrobia	2|Bacteria	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
CH3_k127_8313799_3	1121912.AUHD01000023_gene370	6.719e-67	240.0	28NPX@1|root,2ZBPN@2|Bacteria,4NN00@976|Bacteroidetes,1I1FD@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function DUF2625	-	-	-	-	-	-	-	-	-	-	-	-	DUF2625
CH3_k127_8313799_2	1396418.BATQ01000046_gene6146	2.428e-78	266.0	COG0477@1|root,COG0477@2|Bacteria,46TSP@74201|Verrucomicrobia	74201|Verrucomicrobia	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CH3_k127_8346519_0	177437.HRM2_38050	7.6e-129	419.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,42Q5V@68525|delta/epsilon subdivisions,2WJA1@28221|Deltaproteobacteria,2MJ9S@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfk-1	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
CH3_k127_8346519_2	335543.Sfum_1481	8.285e-20	93.0	2DRBR@1|root,33B4T@2|Bacteria,1NHJT@1224|Proteobacteria,43EE5@68525|delta/epsilon subdivisions,2WSXG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	SpoIIAA-like	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIAA-like
CH3_k127_8346519_3	62928.azo2980	4.346e-05	49.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,2VQ32@28216|Betaproteobacteria,2KW7F@206389|Rhodocyclales	206389|Rhodocyclales	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K07689	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	M00475	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
CH3_k127_8346519_1	756272.Plabr_1285	3.07e-57	210.0	COG1520@1|root,COG1520@2|Bacteria,2IXCF@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
CH3_k127_834823_0	1173027.Mic7113_2682	6.117e-219	709.0	COG4886@1|root,COG4886@2|Bacteria,1G05B@1117|Cyanobacteria,1H6Y6@1150|Oscillatoriales	1117|Cyanobacteria	S	COG4886 Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	COR,LRR_4,LRR_8,Roc
CH3_k127_8379223_3	497964.CfE428DRAFT_0305	8.687e-11	68.0	2DP87@1|root,330Z8@2|Bacteria	497964.CfE428DRAFT_0305|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_8379223_1	478741.JAFS01000002_gene357	6.013e-180	588.0	COG0119@1|root,COG0119@2|Bacteria,46S6Z@74201|Verrucomicrobia,37G7K@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	E	LeuA allosteric (dimerisation) domain	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
CH3_k127_8379223_2	879212.DespoDRAFT_01625	1.889e-40	153.0	COG0614@1|root,COG0614@2|Bacteria,1N7EM@1224|Proteobacteria,42W76@68525|delta/epsilon subdivisions,2WSHJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
CH3_k127_8379223_0	1396141.BATP01000007_gene5676	6.176e-255	818.0	COG0525@1|root,COG0525@2|Bacteria,46SGP@74201|Verrucomicrobia,2IU1F@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
CH3_k127_8403503_3	452637.Oter_3173	2.047e-23	103.0	2EFI3@1|root,339AJ@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4252)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4252
CH3_k127_8403503_1	497964.CfE428DRAFT_3450	7.019e-58	207.0	COG2096@1|root,COG2096@2|Bacteria,46T1G@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Cobalamin adenosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Cob_adeno_trans
CH3_k127_8403503_8	81824.XP_001748107.1	5.762e-05	51.0	COG2132@1|root,2QR4X@2759|Eukaryota,38BK4@33154|Opisthokonta	33154|Opisthokonta	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
CH3_k127_8403503_6	1303518.CCALI_01797	4.752e-15	85.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456,ko:K02650	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,SBP_bac_10,T2SSG
CH3_k127_8403503_0	497964.CfE428DRAFT_3199	1.79e-289	896.0	COG0119@1|root,COG0119@2|Bacteria,46TI3@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
CH3_k127_8403503_7	1121101.HMPREF1532_01485	3.614e-07	63.0	COG0860@1|root,COG0860@2|Bacteria,4PPDZ@976|Bacteroidetes,2G15H@200643|Bacteroidia,4ATKG@815|Bacteroidaceae	976|Bacteroidetes	M	Cna protein B-type domain	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_3
CH3_k127_8403503_5	1173028.ANKO01000014_gene1062	8.766e-19	100.0	COG1572@1|root,COG1572@2|Bacteria,1G2VV@1117|Cyanobacteria,1HAEV@1150|Oscillatoriales	1117|Cyanobacteria	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
CH3_k127_8403503_2	1123008.KB905706_gene883	2.571e-55	203.0	COG3250@1|root,COG3250@2|Bacteria,4NIBS@976|Bacteroidetes,2FPZ2@200643|Bacteroidia,22ZBT@171551|Porphyromonadaceae	976|Bacteroidetes	G	alpha-L-rhamnosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106
CH3_k127_8420600_3	497964.CfE428DRAFT_0568	6.062e-40	153.0	COG0164@1|root,COG0164@2|Bacteria,46SXH@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
CH3_k127_8420600_0	1123248.KB893385_gene4912	3.696e-177	557.0	COG0363@1|root,COG0363@2|Bacteria,4P0EP@976|Bacteroidetes	976|Bacteroidetes	G	glucosamine-6-phosphate deaminase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_8420600_1	1123248.KB893385_gene4913	5.851e-87	295.0	COG2120@1|root,COG2120@2|Bacteria,4P03X@976|Bacteroidetes	976|Bacteroidetes	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
CH3_k127_8420600_2	497964.CfE428DRAFT_2980	4.432e-54	198.0	COG1595@1|root,COG1595@2|Bacteria,46TV8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_8480418_1	234267.Acid_2265	9.614e-181	572.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CH3_k127_8480418_0	234267.Acid_2264	5.565e-226	711.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_2,PSCyt2,PSD1
CH3_k127_8480418_3	926551.KB900703_gene1072	4.82e-17	89.0	COG4124@1|root,COG4124@2|Bacteria,4NEZG@976|Bacteroidetes,1HYFM@117743|Flavobacteriia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 26 family	-	-	3.2.1.78	ko:K01218	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000	-	GH26	-	Glyco_hydro_26
CH3_k127_8480418_2	1499967.BAYZ01000026_gene1631	1.088e-128	434.0	COG0367@1|root,COG0367@2|Bacteria,2NNKE@2323|unclassified Bacteria	2|Bacteria	E	PFAM asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
CH3_k127_8480418_4	497964.CfE428DRAFT_0088	3.179e-06	53.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CH3_k127_8520302_3	1403819.BATR01000031_gene981	9.864e-107	361.0	COG1793@1|root,COG1793@2|Bacteria,46TK9@74201|Verrucomicrobia,2IV60@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CH3_k127_8520302_0	497964.CfE428DRAFT_0415	3.809e-175	560.0	COG2256@1|root,COG2256@2|Bacteria,46S7H@74201|Verrucomicrobia	74201|Verrucomicrobia	L	AAA ATPase central domain protein	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
CH3_k127_8520302_10	344747.PM8797T_00964	1.198e-07	62.0	2FF0U@1|root,346Z8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_8520302_8	1123252.ATZF01000020_gene2901	3.607e-25	112.0	COG0212@1|root,COG0212@2|Bacteria,1VA91@1239|Firmicutes,4HM35@91061|Bacilli,27C4B@186824|Thermoactinomycetaceae	91061|Bacilli	H	5-formyltetrahydrofolate cyclo-ligase family	fthC	GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0030272,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
CH3_k127_8520302_2	1382304.JNIL01000001_gene534	8.523e-139	458.0	COG1418@1|root,COG1418@2|Bacteria,1TP48@1239|Firmicutes,4HC9J@91061|Bacilli,277VR@186823|Alicyclobacillaceae	91061|Bacilli	S	Endoribonuclease that initiates mRNA decay	rny	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
CH3_k127_8520302_11	478741.JAFS01000002_gene111	1.018e-06	59.0	COG1196@1|root,COG1196@2|Bacteria,46Z83@74201|Verrucomicrobia,37GKF@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_8520302_7	391587.KAOT1_16038	3.497e-25	115.0	COG0457@1|root,COG0457@2|Bacteria,4NF5V@976|Bacteroidetes,1HYKU@117743|Flavobacteriia	976|Bacteroidetes	T	tetratricopeptide repeat	batE	-	-	-	-	-	-	-	-	-	-	-	SH3_3,SH3_4,TPR_1,TPR_11,TPR_16,TPR_2
CH3_k127_8520302_5	309807.SRU_2566	6.062e-35	153.0	COG0457@1|root,COG0457@2|Bacteria,4NERG@976|Bacteroidetes,1FJBA@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Oxygen tolerance	-	-	-	-	-	-	-	-	-	-	-	-	BatD
CH3_k127_8520302_6	717605.Theco_1040	1.484e-28	124.0	COG0128@1|root,COG0128@2|Bacteria,1VK19@1239|Firmicutes,4HQZ9@91061|Bacilli,26WZM@186822|Paenibacillaceae	91061|Bacilli	E	3-phosphoshikimate 1-carboxyvinyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_8520302_4	497964.CfE428DRAFT_1897	2.508e-88	304.0	COG0679@1|root,COG0679@2|Bacteria,46SPM@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM Auxin Efflux Carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
CH3_k127_8520302_1	497964.CfE428DRAFT_0339	2.55e-158	514.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,46S9P@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Belongs to the precorrin methyltransferase family	cysG	-	2.1.1.107,4.2.1.75	ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
CH3_k127_8520302_9	321327.CYA_0302	1.511e-13	74.0	COG3271@1|root,COG3271@2|Bacteria,1GPBY@1117|Cyanobacteria,1H2UN@1129|Synechococcus	1117|Cyanobacteria	S	similarity to PIR H75264	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
CH3_k127_8544897_4	926550.CLDAP_37740	9.235e-33	135.0	COG1670@1|root,COG1670@2|Bacteria,2G6UG@200795|Chloroflexi	200795|Chloroflexi	J	COGs COG1670 Acetyltransferase including N-acetylase of ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
CH3_k127_8544897_6	160488.PP_1915	0.0002695	49.0	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,1S8X4@1236|Gammaproteobacteria,1YZ00@136845|Pseudomonas putida group	1236|Gammaproteobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0050896,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
CH3_k127_8544897_3	1192034.CAP_3675	2.408e-42	162.0	2AQBM@1|root,31FHR@2|Bacteria,1QA8C@1224|Proteobacteria,434WG@68525|delta/epsilon subdivisions,2X920@28221|Deltaproteobacteria,2Z1HS@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_8544897_0	269797.Mbar_A1995	7.92e-142	480.0	arCOG02516@1|root,arCOG02538@1|root,arCOG02516@2157|Archaea,arCOG02538@2157|Archaea,2Y7RK@28890|Euryarchaeota,2NBKX@224756|Methanomicrobia	2157|Archaea	S	Leucine rich repeats (6 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,He_PIG,PKD,PQQ_3,Peptidase_S8,S-layer
CH3_k127_8544897_5	1303518.CCALI_01330	5.745e-10	71.0	COG4537@1|root,COG4537@2|Bacteria	2|Bacteria	U	Required for transformation and DNA binding	comGC	GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944	-	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	M00331,M00429	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
CH3_k127_8544897_2	269797.Mbar_A1574	5.746e-56	209.0	COG1262@1|root,arCOG03517@2157|Archaea,2Y27Z@28890|Euryarchaeota	28890|Euryarchaeota	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
CH3_k127_8544897_1	1192034.CAP_0893	1.304e-84	287.0	COG3509@1|root,COG3509@2|Bacteria,1N6M6@1224|Proteobacteria,42U8Z@68525|delta/epsilon subdivisions,2WQQT@28221|Deltaproteobacteria,2YV47@29|Myxococcales	28221|Deltaproteobacteria	Q	Esterase PHB depolymerase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Esterase_phd
CH3_k127_8597487_1	443143.GM18_0683	7.886e-195	621.0	COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,42MNB@68525|delta/epsilon subdivisions,2WIXQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Belongs to the GPI family	pgi	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
CH3_k127_8597487_0	481448.Minf_2402	7.19e-221	703.0	COG0445@1|root,COG0445@2|Bacteria,46SID@74201|Verrucomicrobia,37GAP@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
CH3_k127_8597487_3	1396418.BATQ01000146_gene3489	6.704e-102	340.0	COG1082@1|root,COG1082@2|Bacteria,46SR1@74201|Verrucomicrobia,2IW0I@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CH3_k127_8597487_8	1303518.CCALI_01326	3.414e-41	155.0	COG0393@1|root,COG0393@2|Bacteria	2|Bacteria	S	Putative heavy-metal-binding	ybjQ	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
CH3_k127_8597487_4	744872.Spica_1339	1.199e-73	256.0	COG0217@1|root,COG0217@2|Bacteria,2J634@203691|Spirochaetes	203691|Spirochaetes	K	Transcriptional regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
CH3_k127_8597487_2	314230.DSM3645_16385	2.513e-126	438.0	COG4258@1|root,COG4258@2|Bacteria,2IYH7@203682|Planctomycetes	203682|Planctomycetes	S	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
CH3_k127_8597487_6	269799.Gmet_1270	8.333e-66	245.0	COG3170@1|root,COG3170@2|Bacteria,1MY6X@1224|Proteobacteria,42TBE@68525|delta/epsilon subdivisions,2WPBV@28221|Deltaproteobacteria,43U5N@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_8597487_7	452637.Oter_0685	4.257e-61	219.0	COG0767@1|root,COG0767@2|Bacteria,46ZIM@74201|Verrucomicrobia,3K7D7@414999|Opitutae	414999|Opitutae	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
CH3_k127_8597487_5	1158345.JNLL01000001_gene159	1.772e-73	255.0	COG1127@1|root,COG1127@2|Bacteria,2G3XY@200783|Aquificae	200783|Aquificae	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
CH3_k127_8597487_9	1123371.ATXH01000005_gene2035	1.304e-38	157.0	COG1463@1|root,COG1463@2|Bacteria,2GGR8@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
CH3_k127_8611573_1	452637.Oter_3823	7.297e-178	576.0	COG3693@1|root,COG3934@1|root,COG3693@2|Bacteria,COG3934@2|Bacteria,46S7C@74201|Verrucomicrobia,3K7ED@414999|Opitutae	414999|Opitutae	G	PFAM glycoside hydrolase, family 10	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_8611573_2	452637.Oter_3823	3.645e-67	241.0	COG3693@1|root,COG3934@1|root,COG3693@2|Bacteria,COG3934@2|Bacteria,46S7C@74201|Verrucomicrobia,3K7ED@414999|Opitutae	414999|Opitutae	G	PFAM glycoside hydrolase, family 10	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_8611573_4	1396141.BATP01000006_gene5432	9.891e-05	54.0	COG2312@1|root,COG2885@1|root,COG3209@1|root,COG3210@1|root,COG2312@2|Bacteria,COG2885@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,46XSC@74201|Verrucomicrobia,2IWGQ@203494|Verrucomicrobiae	2|Bacteria	M	CotH kinase protein	-	-	-	ko:K02487,ko:K12543	ko02020,map02020	M00330,M00507	-	-	ko00000,ko00001,ko00002,ko02000,ko02022,ko02035,ko02044	1.B.17,3.A.1.109.4	-	-	CotH,Erythro_esteras,LTD,OmpA
CH3_k127_8611573_3	521674.Plim_1627	2.177e-12	78.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
CH3_k127_8611573_0	1210884.HG799470_gene14529	1.779e-180	572.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,2IY0D@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CH3_k127_8625920_6	1303518.CCALI_00360	5.888e-57	211.0	COG3271@1|root,COG3271@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
CH3_k127_8625920_11	59374.Fisuc_2149	5.609e-24	112.0	COG0705@1|root,COG0705@2|Bacteria	2|Bacteria	S	proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
CH3_k127_8625920_7	497964.CfE428DRAFT_2959	1.585e-46	178.0	2ED0A@1|root,336X9@2|Bacteria,46TCE@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_8625920_8	554065.XP_005846247.1	6.902e-36	143.0	COG1011@1|root,KOG3085@2759|Eukaryota,382V1@33090|Viridiplantae	33090|Viridiplantae	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_8625920_3	570268.ANBB01000059_gene4179	5.439e-64	224.0	COG0353@1|root,COG0353@2|Bacteria,2GJY0@201174|Actinobacteria,4EG4M@85012|Streptosporangiales	201174|Actinobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
CH3_k127_8625920_10	1121472.AQWN01000007_gene1087	4.443e-24	107.0	COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,24MXH@186801|Clostridia,262CP@186807|Peptococcaceae	186801|Clostridia	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
CH3_k127_8625920_1	1396418.BATQ01000129_gene4821	5.864e-132	442.0	COG2812@1|root,COG2812@2|Bacteria,46SGC@74201|Verrucomicrobia,2ITGI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
CH3_k127_8625920_2	435591.BDI_2467	1.013e-90	315.0	COG5434@1|root,COG5434@2|Bacteria,4NFSC@976|Bacteroidetes,2FNQN@200643|Bacteroidia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 28 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_28,Pectate_lyase_3
CH3_k127_8625920_0	794903.OPIT5_28170	3.096e-210	668.0	COG0519@1|root,COG0519@2|Bacteria,46SIW@74201|Verrucomicrobia,3K77S@414999|Opitutae	414999|Opitutae	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
CH3_k127_8625920_4	1122919.KB905591_gene4021	1.855e-61	230.0	COG1520@1|root,COG1520@2|Bacteria,1UIHU@1239|Firmicutes,4ISIB@91061|Bacilli,2773B@186822|Paenibacillaceae	91061|Bacilli	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_8625920_13	1123276.KB893252_gene3670	3.55e-15	89.0	COG2755@1|root,COG2931@1|root,COG3210@1|root,COG3391@1|root,COG4625@1|root,COG4886@1|root,COG5184@1|root,COG5492@1|root,COG2755@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3391@2|Bacteria,COG4625@2|Bacteria,COG4886@2|Bacteria,COG5184@2|Bacteria,COG5492@2|Bacteria,4PPHP@976|Bacteroidetes,47XC8@768503|Cytophagia	976|Bacteroidetes	E	Cadherin repeats.	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG
CH3_k127_8625920_5	1192034.CAP_0893	9.47e-59	231.0	COG3509@1|root,COG3509@2|Bacteria,1N6M6@1224|Proteobacteria,42U8Z@68525|delta/epsilon subdivisions,2WQQT@28221|Deltaproteobacteria,2YV47@29|Myxococcales	28221|Deltaproteobacteria	Q	Esterase PHB depolymerase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Esterase_phd
CH3_k127_8625920_9	203124.Tery_0657	4.638e-28	132.0	COG3391@1|root,COG3391@2|Bacteria,1G0EB@1117|Cyanobacteria,1H803@1150|Oscillatoriales	1117|Cyanobacteria	G	PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Calx-beta,DUF4347,He_PIG,HemolysinCabind,PPC,TIG,VCBS
CH3_k127_8625920_12	179408.Osc7112_0620	8.718e-24	108.0	COG2319@1|root,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria	1117|Cyanobacteria	A	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	AAA_35,WD40
CH3_k127_8628810_2	452637.Oter_1480	3.532e-39	148.0	COG1451@1|root,COG1451@2|Bacteria,46VW6@74201|Verrucomicrobia,3K7I9@414999|Opitutae	414999|Opitutae	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
CH3_k127_8628810_1	365046.Rta_21390	2.635e-80	270.0	COG0322@1|root,COG0322@2|Bacteria,1R5TC@1224|Proteobacteria,2VHTS@28216|Betaproteobacteria,4AEWB@80864|Comamonadaceae	28216|Betaproteobacteria	L	Domain of unknown function (DUF4357)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4357,GIY-YIG
CH3_k127_8642572_7	1449355.JQNR01000005_gene5972	8.543e-06	59.0	COG3055@1|root,COG4934@1|root,COG3055@2|Bacteria,COG4934@2|Bacteria,2IF2T@201174|Actinobacteria	201174|Actinobacteria	O	Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Kelch_1
CH3_k127_8642572_4	1168059.KB899087_gene3167	2.772e-21	111.0	COG1409@1|root,COG2931@1|root,COG1409@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,3EZXC@335928|Xanthobacteraceae	28211|Alphaproteobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CBM60,HemolysinCabind,Metallophos,PPC,Peptidase_M10_C
CH3_k127_8642572_1	1121920.AUAU01000009_gene1881	2.016e-51	211.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,I-set,Ig_3,PKD,Peptidase_S8
CH3_k127_8642572_6	1303518.CCALI_00913	3.137e-17	92.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
CH3_k127_8642572_2	1123296.JQKE01000075_gene375	1.698e-37	156.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2VM3A@28216|Betaproteobacteria,2KPMA@206351|Neisseriales	206351|Neisseriales	KLT	Psort location Extracellular, score	-	-	-	-	-	-	-	-	-	-	-	-	Sel1
CH3_k127_8642572_5	497964.CfE428DRAFT_0698	9.444e-21	97.0	COG3558@1|root,COG3558@2|Bacteria,46T07@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF5069)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5069
CH3_k127_8642572_3	575609.HMPREF0629_01045	3.334e-22	105.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,24MVR@186801|Clostridia,22HAS@1570339|Peptoniphilaceae	186801|Clostridia	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
CH3_k127_8642572_0	1396418.BATQ01000026_gene5276	5.581e-160	508.0	COG0156@1|root,COG0156@2|Bacteria,46SSH@74201|Verrucomicrobia,2ITW1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminotransferase class I and II	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CH3_k127_8649544_3	204669.Acid345_2839	5.188e-106	347.0	COG0399@1|root,COG0399@2|Bacteria,3Y422@57723|Acidobacteria,2JHQV@204432|Acidobacteriia	204432|Acidobacteriia	E	Belongs to the DegT DnrJ EryC1 family	-	-	1.17.1.1	ko:K12452	ko00520,map00520	-	R03391,R03392	RC00230	ko00000,ko00001,ko01000	-	-	-	DegT_DnrJ_EryC1
CH3_k127_8649544_0	449447.MAE_11020	4.457e-138	447.0	COG0451@1|root,COG0451@2|Bacteria,1GDNX@1117|Cyanobacteria	1117|Cyanobacteria	GM	GDP-mannose 4,6 dehydratase	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
CH3_k127_8649544_1	396014.BF93_10610	5.651e-136	449.0	COG2721@1|root,COG2721@2|Bacteria,2GJC8@201174|Actinobacteria	201174|Actinobacteria	G	D-galactarate dehydratase Altronate	-	-	4.2.1.42,4.2.1.7	ko:K01685,ko:K01708	ko00040,ko00053,ko01100,map00040,map00053,map01100	M00631	R01540,R05608	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	GD_AH_C,SAF
CH3_k127_8649544_4	710687.KI912270_gene2448	3.502e-66	240.0	COG0246@1|root,COG0246@2|Bacteria	2|Bacteria	G	mannitol metabolic process	mtlD	-	1.1.1.17	ko:K00009	ko00051,map00051	-	R02703	RC00085	ko00000,ko00001,ko01000	-	-	-	Mannitol_dh,Mannitol_dh_C
CH3_k127_8649544_6	1267211.KI669560_gene554	2.503e-18	96.0	COG0483@1|root,COG0483@2|Bacteria,4NI6D@976|Bacteroidetes,1IQ46@117747|Sphingobacteriia	976|Bacteroidetes	G	Inositol monophosphatase	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
CH3_k127_8649544_5	1183438.GKIL_1903	7.13e-22	107.0	COG1208@1|root,COG1208@2|Bacteria,1G00Y@1117|Cyanobacteria	1117|Cyanobacteria	JM	Glucose-1-phosphate cytidylyltransferase	rfbF	-	2.7.7.33	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	-	R00956	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
CH3_k127_8649544_2	1131269.AQVV01000023_gene2383	5.733e-116	387.0	COG0028@1|root,COG0028@2|Bacteria	2|Bacteria	EH	Belongs to the TPP enzyme family	ilvB2	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CH3_k127_8671432_2	314256.OG2516_10466	1.209e-40	158.0	COG1082@1|root,COG1082@2|Bacteria,1MWJ3@1224|Proteobacteria,2TR21@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	sugar phosphate	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CH3_k127_8671432_4	1280947.HY30_08240	4.081e-11	74.0	COG0697@1|root,COG0697@2|Bacteria,1MXCD@1224|Proteobacteria,2TR27@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	MA20_19820	-	-	-	-	-	-	-	-	-	-	-	EamA
CH3_k127_8671432_1	497964.CfE428DRAFT_5399	9.218e-68	248.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
CH3_k127_8671432_0	497964.CfE428DRAFT_5400	5.344e-92	308.0	COG1136@1|root,COG1136@2|Bacteria	2|Bacteria	V	lipoprotein transporter activity	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CH3_k127_8671432_3	497964.CfE428DRAFT_5401	1.457e-26	118.0	COG0577@1|root,COG0577@2|Bacteria,46U7K@74201|Verrucomicrobia	74201|Verrucomicrobia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
CH3_k127_868234_6	1396141.BATP01000007_gene5571	0.0001537	54.0	COG0584@1|root,COG0584@2|Bacteria	2|Bacteria	C	glycerophosphodiester phosphodiesterase activity	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD,GPDPase_memb
CH3_k127_868234_3	497964.CfE428DRAFT_2458	1.84e-80	275.0	COG4798@1|root,COG4798@2|Bacteria,46T4I@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Met-10+ like-protein	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
CH3_k127_868234_1	452637.Oter_1107	1.53e-84	291.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,46V45@74201|Verrucomicrobia	74201|Verrucomicrobia	K	helix_turn_helix, mercury resistance	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
CH3_k127_868234_2	497964.CfE428DRAFT_4839	8.668e-82	285.0	COG0568@1|root,COG0568@2|Bacteria,46SJ8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
CH3_k127_868234_5	595460.RRSWK_05296	2.955e-16	93.0	COG1012@1|root,COG1012@2|Bacteria,2IZ2G@203682|Planctomycetes	203682|Planctomycetes	C	Aldehyde dehydrogenase family	-	-	1.2.1.3,1.2.99.10	ko:K00128,ko:K22445	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CH3_k127_868234_0	344747.PM8797T_20643	5.798e-143	475.0	COG1520@1|root,COG1520@2|Bacteria,2IX2Z@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CH3_k127_868234_4	1198114.AciX9_0857	1.058e-42	165.0	COG0204@1|root,COG0204@2|Bacteria,3Y530@57723|Acidobacteria,2JJKR@204432|Acidobacteriia	204432|Acidobacteriia	I	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
CH3_k127_8700687_8	1340493.JNIF01000003_gene3916	4.048e-85	300.0	COG2006@1|root,COG2006@2|Bacteria,3Y6M1@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
CH3_k127_8700687_7	497964.CfE428DRAFT_0699	1.287e-85	301.0	COG0745@1|root,COG1235@1|root,COG0745@2|Bacteria,COG1235@2|Bacteria,46UKB@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
CH3_k127_8700687_5	1403819.BATR01000153_gene5138	6.267e-137	450.0	COG4948@1|root,COG4948@2|Bacteria,46S7G@74201|Verrucomicrobia,2IV9V@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Mandelate Racemase Muconate Lactonizing	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_8700687_4	1340493.JNIF01000003_gene1832	9.926e-159	507.0	COG0620@1|root,COG0620@2|Bacteria	2|Bacteria	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
CH3_k127_8700687_19	497964.CfE428DRAFT_1412	3.635e-07	65.0	COG3250@1|root,COG4677@1|root,COG4932@1|root,COG3250@2|Bacteria,COG4677@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	3.1.1.11,3.2.1.55	ko:K01051,ko:K10297,ko:K20844	ko00040,ko00520,ko01100,map00040,map00520,map01100	M00081	R01762,R02362	RC00460,RC00461	ko00000,ko00001,ko00002,ko01000,ko04121	-	CBM42,GH54	-	AbfB,ArabFuran-catal,Beta_helix,Big_4,F5_F8_type_C,Glyco_hydr_30_2,Pectinesterase,RicinB_lectin_2
CH3_k127_8700687_17	1396141.BATP01000007_gene5571	4.071e-16	94.0	COG0584@1|root,COG0584@2|Bacteria	2|Bacteria	C	glycerophosphodiester phosphodiesterase activity	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD,GPDPase_memb
CH3_k127_8700687_0	886293.Sinac_6122	2.145e-289	945.0	COG3391@1|root,COG3511@1|root,COG3391@2|Bacteria,COG3511@2|Bacteria,2IYNB@203682|Planctomycetes	203682|Planctomycetes	M	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase,Phosphoesterase
CH3_k127_8700687_20	1042377.AFPJ01000055_gene971	6.057e-07	59.0	COG1596@1|root,COG1596@2|Bacteria,1MXYS@1224|Proteobacteria,1S85D@1236|Gammaproteobacteria,468T5@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K20988	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
CH3_k127_8700687_18	700598.Niako_6563	4.666e-08	56.0	COG0726@1|root,COG0726@2|Bacteria,4NFJP@976|Bacteroidetes,1IQSF@117747|Sphingobacteriia	976|Bacteroidetes	G	polysaccharide deacetylase	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CelD_N,Glyco_hydro_9,Polysacc_deac_1
CH3_k127_8700687_14	232348.ADXL01000014_gene730	1.045e-30	123.0	COG4634@1|root,COG4634@2|Bacteria,1G6S3@1117|Cyanobacteria,1H23Q@1129|Synechococcus	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_8700687_15	278957.ABEA03000095_gene4585	1.634e-24	104.0	COG2442@1|root,COG2442@2|Bacteria	2|Bacteria	K	InterPro IPR007367	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
CH3_k127_8700687_2	1121904.ARBP01000038_gene2566	2.234e-198	637.0	COG0726@1|root,COG0726@2|Bacteria,4NFJP@976|Bacteroidetes,47JTA@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolase family 9	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CelD_N,Glyco_hydro_9
CH3_k127_8700687_11	485917.Phep_0675	3.732e-59	229.0	COG0726@1|root,COG0726@2|Bacteria,4NFJP@976|Bacteroidetes,1IQSF@117747|Sphingobacteriia	976|Bacteroidetes	G	polysaccharide deacetylase	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CelD_N,Glyco_hydro_9,Polysacc_deac_1
CH3_k127_8700687_3	1123508.JH636444_gene5476	1.968e-194	626.0	COG5316@1|root,COG5316@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139
CH3_k127_8700687_1	344747.PM8797T_29842	1.586e-205	660.0	COG1073@1|root,COG1073@2|Bacteria,2IWSQ@203682|Planctomycetes	203682|Planctomycetes	S	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	AXE1
CH3_k127_8700687_16	1035193.HMPREF9073_01297	8.616e-24	113.0	COG0463@1|root,COG0463@2|Bacteria,4P0ZE@976|Bacteroidetes	976|Bacteroidetes	M	Glycosyltransferase, group 2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CH3_k127_8700687_22	481448.Minf_0708	5.983e-05	53.0	COG2242@1|root,COG2242@2|Bacteria,46WJ6@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
CH3_k127_8700687_13	497964.CfE428DRAFT_1387	3.445e-38	158.0	COG0860@1|root,COG0860@2|Bacteria,46SS7@74201|Verrucomicrobia	74201|Verrucomicrobia	M	PFAM cell wall hydrolase autolysin	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
CH3_k127_8700687_9	497964.CfE428DRAFT_6143	3.106e-62	221.0	COG0163@1|root,COG0163@2|Bacteria,46V9E@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
CH3_k127_8700687_10	984262.SGRA_1441	1.753e-59	218.0	COG0382@1|root,COG0382@2|Bacteria,4NEE3@976|Bacteroidetes,1IP3B@117747|Sphingobacteriia	976|Bacteroidetes	H	4-hydroxybenzoate polyprenyltransferase	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
CH3_k127_8700687_6	1121904.ARBP01000042_gene4905	3.668e-115	400.0	COG3292@1|root,COG3292@2|Bacteria,4NF9I@976|Bacteroidetes,47XHD@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
CH3_k127_8700687_23	1396141.BATP01000060_gene4559	0.0004003	48.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR,PSII_BNR
CH3_k127_8700687_12	452637.Oter_4097	1.02e-53	196.0	COG0385@1|root,COG0385@2|Bacteria,46YMH@74201|Verrucomicrobia,3K9UA@414999|Opitutae	414999|Opitutae	S	Bile acid sodium symporter	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
CH3_k127_870829_1	1304885.AUEY01000003_gene463	5.612e-110	361.0	28M5B@1|root,2ZAJ4@2|Bacteria,1R7Y9@1224|Proteobacteria,42ZPF@68525|delta/epsilon subdivisions,2WUYS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_870829_2	264198.Reut_A1205	2.04e-91	315.0	29MQ2@1|root,308MT@2|Bacteria,1REUR@1224|Proteobacteria,2VXQA@28216|Betaproteobacteria,1K3YT@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_870829_0	1144325.PMI22_03042	4.75e-112	367.0	COG4320@1|root,COG4320@2|Bacteria,1N6EW@1224|Proteobacteria,1S7YN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2252
CH3_k127_8711117_0	497964.CfE428DRAFT_4707	2.96e-140	452.0	COG1060@1|root,COG1060@2|Bacteria	2|Bacteria	H	7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity	mqnC	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188	1.21.98.1,2.5.1.77	ko:K11779,ko:K11780,ko:K11781,ko:K11784	ko00130,ko00680,ko01110,ko01120,map00130,map00680,map01110,map01120	M00378	R08588,R09396	RC01381,RC02329,RC03002,RC03007	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
CH3_k127_8711117_1	314230.DSM3645_26734	3.34e-106	355.0	COG0451@1|root,COG0451@2|Bacteria,2IXGI@203682|Planctomycetes	203682|Planctomycetes	GM	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
CH3_k127_8711117_2	314230.DSM3645_26739	2.152e-86	292.0	COG0329@1|root,COG0329@2|Bacteria,2IXEF@203682|Planctomycetes	203682|Planctomycetes	EM	Belongs to the DapA family	-	-	-	-	-	-	-	-	-	-	-	-	DHDPS
CH3_k127_8744332_5	1396141.BATP01000043_gene1934	3.2e-51	184.0	COG1064@1|root,COG1064@2|Bacteria,46UV2@74201|Verrucomicrobia,2IVEY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
CH3_k127_8744332_7	1123070.KB899247_gene1500	1.841e-31	127.0	2ERYI@1|root,33JHP@2|Bacteria,46WPE@74201|Verrucomicrobia,2IUEZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_8744332_1	886293.Sinac_0668	1.342e-133	440.0	COG0399@1|root,COG0399@2|Bacteria	2|Bacteria	E	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
CH3_k127_8744332_0	761193.Runsl_1895	2.947e-154	499.0	COG1520@1|root,COG1520@2|Bacteria,4NK4X@976|Bacteroidetes,47KWI@768503|Cytophagia	976|Bacteroidetes	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_8744332_2	1340493.JNIF01000003_gene3009	3.164e-127	423.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Oxidoreduct_C,PmoA
CH3_k127_8744332_8	1173026.Glo7428_3849	1.182e-19	91.0	COG1724@1|root,COG1724@2|Bacteria,1G9Z7@1117|Cyanobacteria	1117|Cyanobacteria	N	PFAM YcfA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
CH3_k127_8744332_9	111780.Sta7437_3418	1.77e-18	89.0	COG1598@1|root,COG1598@2|Bacteria,1GAU7@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_8744332_4	1121957.ATVL01000014_gene1459	1.048e-75	273.0	COG5563@1|root,COG5563@2|Bacteria,4PHUI@976|Bacteroidetes,47VHU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_8744332_3	1313304.CALK_1499	6.897e-100	332.0	COG0363@1|root,COG0363@2|Bacteria	2|Bacteria	G	glucosamine-6-phosphate deaminase activity	nagB	GO:0003674,GO:0003824,GO:0004342,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006040,GO:0006044,GO:0006046,GO:0006047,GO:0006048,GO:0006054,GO:0006082,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016054,GO:0016787,GO:0016853,GO:0016860,GO:0016861,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0019239,GO:0019262,GO:0019438,GO:0019752,GO:0034641,GO:0034654,GO:0042737,GO:0042802,GO:0043436,GO:0043877,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046348,GO:0046349,GO:0046395,GO:0046483,GO:0055086,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901362,GO:1901575,GO:1901576	3.1.1.31,3.5.99.6	ko:K01057,ko:K02080,ko:K02564	ko00030,ko00052,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00052,map00520,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R00765,R02035,R08365	RC00163,RC00537	ko00000,ko00001,ko00002,ko01000	-	-	iB21_1397.B21_02959,iECB_1328.ECB_03008,iECD_1391.ECD_03008,iECNA114_1301.ECNA114_3225,iECSF_1327.ECSF_2979,iYO844.BSU02360,iYO844.BSU35020,iZ_1308.Z0825	Glucosamine_iso,PIG-L
CH3_k127_8744332_10	1266908.AQPB01000038_gene531	1.284e-08	63.0	COG3428@1|root,COG3428@2|Bacteria,1N3Z5@1224|Proteobacteria,1SAN2@1236|Gammaproteobacteria,1WYRT@135613|Chromatiales	135613|Chromatiales	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
CH3_k127_8744332_6	1313304.CALK_1498	2.547e-44	167.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CH3_k127_8789925_4	199310.c3928	4.551e-08	55.0	2AWWG@1|root,31NU0@2|Bacteria,1NMXT@1224|Proteobacteria,1SIEV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_8789925_1	234267.Acid_4959	7.222e-108	379.0	COG0784@1|root,COG2202@1|root,COG2203@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,3Y63K@57723|Acidobacteria	57723|Acidobacteria	T	ATP-binding region, ATPase domain protein domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_9,Response_reg
CH3_k127_8789925_0	497964.CfE428DRAFT_0970	1.345e-249	793.0	COG0457@1|root,COG0457@2|Bacteria,46UPB@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Paired_CXXCH_1,TPR_8
CH3_k127_8789925_3	671143.DAMO_1689	2.969e-31	131.0	COG4309@1|root,COG4309@2|Bacteria	2|Bacteria	D	conserved protein (DUF2249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1858,DUF2249
CH3_k127_8789925_2	671143.DAMO_1688	7.5e-46	177.0	COG3278@1|root,COG3278@2|Bacteria,2NRHY@2323|unclassified Bacteria	2|Bacteria	O	Belongs to the heme-copper respiratory oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_8801807_13	1121920.AUAU01000005_gene1059	1.606e-41	164.0	2B9NZ@1|root,3231D@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1579)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1579
CH3_k127_8801807_9	1242864.D187_003284	6.562e-62	216.0	COG5646@1|root,COG5646@2|Bacteria	2|Bacteria	S	Domain of unknown function (DU1801)	XK27_02315	-	-	-	-	-	-	-	-	-	-	-	DUF1801
CH3_k127_8801807_11	1123377.AUIV01000014_gene517	2.482e-51	188.0	COG4430@1|root,COG4430@2|Bacteria,1RG2R@1224|Proteobacteria,1T0AD@1236|Gammaproteobacteria,1X6JK@135614|Xanthomonadales	135614|Xanthomonadales	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801,OmdA
CH3_k127_8801807_28	1121333.JMLH01000086_gene1317	1.907e-05	59.0	COG1196@1|root,COG1524@1|root,COG1196@2|Bacteria,COG1524@2|Bacteria,1UKCI@1239|Firmicutes,3VUT8@526524|Erysipelotrichia	526524|Erysipelotrichia	D	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FIVAR,Laminin_G_3
CH3_k127_8801807_19	1121920.AUAU01000009_gene1881	7.078e-26	126.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,I-set,Ig_3,PKD,Peptidase_S8
CH3_k127_8801807_29	1122927.KB895414_gene5036	0.0001306	56.0	COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,4HANW@91061|Bacilli,26QRR@186822|Paenibacillaceae	91061|Bacilli	G	beta-galactosidase	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Laminin_G_3,NPCBM
CH3_k127_8801807_26	479435.Kfla_2748	4.989e-09	71.0	COG3391@1|root,COG3391@2|Bacteria,2I2VV@201174|Actinobacteria,4DTEE@85009|Propionibacteriales	201174|Actinobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,Laminin_G_3
CH3_k127_8801807_22	1142394.PSMK_06110	9.118e-17	91.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
CH3_k127_8801807_5	756272.Plabr_2335	5.083e-102	347.0	COG2755@1|root,COG2755@2|Bacteria,2IYGD@203682|Planctomycetes	203682|Planctomycetes	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CH3_k127_8801807_4	240016.ABIZ01000001_gene3008	1.223e-147	480.0	COG1520@1|root,COG1520@2|Bacteria,46U6I@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CH3_k127_8801807_14	583355.Caka_1943	2.587e-41	158.0	COG1051@1|root,COG1051@2|Bacteria,46V5B@74201|Verrucomicrobia,3K7WB@414999|Opitutae	414999|Opitutae	F	NUDIX hydrolase	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
CH3_k127_8801807_8	1144275.COCOR_06959	1.269e-74	266.0	COG0404@1|root,COG0404@2|Bacteria,1QX3Y@1224|Proteobacteria,43BWD@68525|delta/epsilon subdivisions,2X775@28221|Deltaproteobacteria,2YVVR@29|Myxococcales	28221|Deltaproteobacteria	E	Glycine cleavage T-protein C-terminal barrel domain	-	-	2.1.2.10	ko:K00605,ko:K06980	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	GCV_T,GCV_T_C
CH3_k127_8801807_7	1403819.BATR01000112_gene3876	4.557e-80	278.0	COG1082@1|root,COG1082@2|Bacteria,46T96@74201|Verrucomicrobia,2IUNM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CH3_k127_8801807_16	240016.ABIZ01000001_gene3878	6.754e-34	141.0	COG2068@1|root,COG2068@2|Bacteria	2|Bacteria	NU	MobA-Related Protein	nboR	-	1.1.1.328,2.7.7.76	ko:K07141,ko:K19190	ko00760,ko00790,ko01120,map00760,map00790,map01120	-	R10131,R10132,R11582	RC03053	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
CH3_k127_8801807_21	794903.OPIT5_29840	1.429e-23	107.0	2FBS3@1|root,307HF@2|Bacteria,46W7T@74201|Verrucomicrobia,3K85M@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_8801807_10	530564.Psta_2414	8.649e-52	186.0	COG0346@1|root,COG0346@2|Bacteria,2J1AZ@203682|Planctomycetes	203682|Planctomycetes	E	Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CH3_k127_8801807_1	497964.CfE428DRAFT_3658	1.321e-166	537.0	COG2273@1|root,COG2273@2|Bacteria	2|Bacteria	G	xyloglucan:xyloglucosyl transferase activity	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	CBM_6,Glyco_hydro_16,Trypsin,VCBS
CH3_k127_8801807_25	794903.OPIT5_11525	4.338e-12	76.0	COG2165@1|root,COG2165@2|Bacteria,46Z9D@74201|Verrucomicrobia,3K9IE@414999|Opitutae	2|Bacteria	U	Protein of unknown function (DUF1559)	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
CH3_k127_8801807_20	452637.Oter_3570	2.949e-25	117.0	COG0265@1|root,COG0265@2|Bacteria,46W40@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_8801807_3	1396141.BATP01000032_gene4324	2.188e-157	521.0	COG0265@1|root,COG0265@2|Bacteria,46SHP@74201|Verrucomicrobia,2IU51@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Trypsin	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
CH3_k127_8801807_12	497964.CfE428DRAFT_5735	4.496e-45	183.0	COG4796@1|root,COG4796@2|Bacteria,46STU@74201|Verrucomicrobia	74201|Verrucomicrobia	U	PFAM type II and III secretion system protein	-	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	Secretin
CH3_k127_8801807_18	404589.Anae109_0686	5.419e-28	126.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,42M36@68525|delta/epsilon subdivisions,2WJFJ@28221|Deltaproteobacteria,2YUJQ@29|Myxococcales	28221|Deltaproteobacteria	NU	pilus assembly protein	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
CH3_k127_8801807_6	240016.ABIZ01000001_gene654	4.552e-80	277.0	COG0583@1|root,COG0583@2|Bacteria,46V15@74201|Verrucomicrobia,2IUGE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CH3_k127_8801807_15	497964.CfE428DRAFT_1024	9.486e-40	152.0	2EBIG@1|root,335IZ@2|Bacteria,46WF8@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_8801807_2	1123242.JH636435_gene1594	1.637e-157	511.0	COG1032@1|root,COG1032@2|Bacteria,2IYYP@203682|Planctomycetes	203682|Planctomycetes	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
CH3_k127_8801807_0	404589.Anae109_0189	0.0	1470.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,1PKG6@1224|Proteobacteria,42MY4@68525|delta/epsilon subdivisions,2WJFI@28221|Deltaproteobacteria,2YVGM@29|Myxococcales	28221|Deltaproteobacteria	I	CoA-substrate-specific enzyme activase	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
CH3_k127_8801807_23	991.IW20_16285	3.318e-15	87.0	COG1470@1|root,COG3386@1|root,COG1470@2|Bacteria,COG3386@2|Bacteria,4PKCK@976|Bacteroidetes,1IJ7K@117743|Flavobacteriia,2P0KA@237|Flavobacterium	976|Bacteroidetes	G	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_8801807_17	886293.Sinac_0620	1.42e-30	132.0	2EEBB@1|root,30UIG@2|Bacteria,2J420@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_8801807_27	197221.22295598	4.907e-06	58.0	COG0236@1|root,COG0236@2|Bacteria,1G9GC@1117|Cyanobacteria	1117|Cyanobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
CH3_k127_8801807_24	316067.Geob_3122	2.674e-12	78.0	COG0236@1|root,COG0236@2|Bacteria,1NE99@1224|Proteobacteria	1224|Proteobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_8818996_15	794903.OPIT5_26235	0.0005554	51.0	2A3EY@1|root,31MUJ@2|Bacteria,46X6D@74201|Verrucomicrobia,3K9KW@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_8818996_14	1210884.HG799463_gene10210	1.436e-08	68.0	COG4972@1|root,COG4972@2|Bacteria,2IWXB@203682|Planctomycetes	203682|Planctomycetes	NU	TIGRFAM type IV pilus assembly protein PilM	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
CH3_k127_8818996_0	794903.OPIT5_26245	4.234e-188	613.0	COG4796@1|root,COG4796@2|Bacteria,46Y4X@74201|Verrucomicrobia,3K8XV@414999|Opitutae	414999|Opitutae	U	Bacterial type II and III secretion system protein	-	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	Secretin
CH3_k127_8818996_7	945713.IALB_1744	4.814e-45	168.0	COG0691@1|root,COG0691@2|Bacteria	2|Bacteria	O	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070930,GO:0071704,GO:0097159,GO:1901363,GO:1901564	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
CH3_k127_8818996_13	382464.ABSI01000005_gene1329	7.226e-09	61.0	COG1758@1|root,COG1758@2|Bacteria,46W29@74201|Verrucomicrobia,2IUQD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	RNA polymerase activity	-	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
CH3_k127_8818996_12	56107.Cylst_5717	1.232e-14	87.0	COG1413@1|root,COG1672@1|root,COG1413@2|Bacteria,COG1672@2|Bacteria,1G2R4@1117|Cyanobacteria,1HMQH@1161|Nostocales	1117|Cyanobacteria	CT	HEAT repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HEAT,HEAT_2,HEAT_PBS
CH3_k127_8818996_11	1403819.BATR01000182_gene6270	3.178e-27	129.0	COG0457@1|root,COG1196@1|root,COG0457@2|Bacteria,COG1196@2|Bacteria,46T1H@74201|Verrucomicrobia,2IUR7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	D	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_8
CH3_k127_8818996_5	543728.Vapar_2851	1.9e-58	205.0	COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,2WBQC@28216|Betaproteobacteria,4AI59@80864|Comamonadaceae	28216|Betaproteobacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
CH3_k127_8818996_1	886293.Sinac_1932	1.513e-102	362.0	COG2706@1|root,COG2706@2|Bacteria,2J55E@203682|Planctomycetes	203682|Planctomycetes	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
CH3_k127_8818996_3	316067.Geob_3008	4.523e-90	309.0	COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,42NGR@68525|delta/epsilon subdivisions,2WIMA@28221|Deltaproteobacteria,43TMT@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6,5.4.99.58	ko:K01012,ko:K16180	ko00300,ko00780,ko01100,ko01120,map00300,map00780,map01100,map01120	M00123,M00573,M00577	R01078,R10010	RC00441,RC02995	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1582	BATS,Radical_SAM
CH3_k127_8818996_4	452637.Oter_2645	1.262e-73	257.0	COG2866@1|root,COG2866@2|Bacteria,46T00@74201|Verrucomicrobia,3K83I@414999|Opitutae	414999|Opitutae	E	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	-	-	-	-	-	-	-	-	-	AstE_AspA
CH3_k127_8818996_9	1123489.AUAN01000002_gene1017	8.272e-40	158.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,4H2BH@909932|Negativicutes	909932|Negativicutes	KLT	serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
CH3_k127_8818996_8	1396141.BATP01000058_gene1952	4.333e-44	172.0	COG1040@1|root,COG1040@2|Bacteria,46T0D@74201|Verrucomicrobia,2IUGQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	competence protein	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
CH3_k127_8818996_2	497964.CfE428DRAFT_2029	9.753e-101	338.0	COG0777@1|root,COG0777@2|Bacteria,46SI0@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
CH3_k127_8818996_10	1156937.MFUM_930026	9.993e-37	149.0	COG4137@1|root,COG4137@2|Bacteria,46T0T@74201|Verrucomicrobia,37GN8@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Cytochrome C assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
CH3_k127_8818996_6	1396141.BATP01000057_gene2984	2.342e-47	179.0	COG0373@1|root,COG0373@2|Bacteria,46SMQ@74201|Verrucomicrobia,2IU0T@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Glutamyl-tRNAGlu reductase, N-terminal domain	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,Shikimate_DH
CH3_k127_8832599_2	1536769.P40081_08725	1.309e-16	88.0	COG0457@1|root,COG0457@2|Bacteria,1V2VW@1239|Firmicutes,4IQEM@91061|Bacilli,276C8@186822|Paenibacillaceae	91061|Bacilli	S	Tetratricopeptide repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5107,TPR_16,TPR_8
CH3_k127_8832599_1	661478.OP10G_0633	4.05e-268	834.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
CH3_k127_8832599_3	1304885.AUEY01000005_gene869	7.323e-15	76.0	2DR98@1|root,33ARN@2|Bacteria,1NHFU@1224|Proteobacteria,42X3T@68525|delta/epsilon subdivisions,2WSSX@28221|Deltaproteobacteria,2MMBR@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Putative addiction module component	-	-	-	-	-	-	-	-	-	-	-	-	Unstab_antitox
CH3_k127_8832599_4	161156.JQKW01000008_gene436	2.768e-13	75.0	COG3668@1|root,COG3668@2|Bacteria	2|Bacteria	D	Plasmid stabilization system	-	GO:0008150,GO:0040008,GO:0045926,GO:0048519,GO:0050789,GO:0065007	-	ko:K19093	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
CH3_k127_8832599_0	1499967.BAYZ01000009_gene5298	3.638e-315	998.0	COG0587@1|root,COG0587@2|Bacteria,2NNVY@2323|unclassified Bacteria	2|Bacteria	L	DNA polymerase	dnaE	GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
CH3_k127_8844635_1	886293.Sinac_6968	6.257e-149	480.0	COG4654@1|root,COG4654@2|Bacteria,2IX0M@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,PSCyt1,PSCyt2,PSD1
CH3_k127_8844635_0	1123508.JH636445_gene6536	8.23e-192	612.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG3828@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,COG3828@2|Bacteria,2IX4V@203682|Planctomycetes	203682|Planctomycetes	C	COG2133 Glucose sorbosone dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
CH3_k127_8855419_3	1198452.Jab_2c29700	1.026e-06	62.0	COG3227@1|root,COG3227@2|Bacteria,1R61F@1224|Proteobacteria,2VUWX@28216|Betaproteobacteria,474TB@75682|Oxalobacteraceae	28216|Betaproteobacteria	E	Thermolysin metallopeptidase, alpha-helical domain	-	-	-	ko:K20273	ko02024,map02024	-	-	-	ko00000,ko00001,ko01002	-	-	-	FTP,Peptidase_M4,Peptidase_M4_C
CH3_k127_8855419_1	243090.RB4375	3.803e-24	119.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF642
CH3_k127_8855419_2	1173028.ANKO01000041_gene3212	4.471e-10	67.0	COG2931@1|root,COG2931@2|Bacteria,1G0ZC@1117|Cyanobacteria,1H8KD@1150|Oscillatoriales	1117|Cyanobacteria	Q	PFAM Hemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Calx-beta,Chlam_PMP,DUF4347,HemolysinCabind
CH3_k127_8855419_0	497964.CfE428DRAFT_5662	1.651e-94	321.0	COG0249@1|root,COG0249@2|Bacteria,46SCK@74201|Verrucomicrobia	74201|Verrucomicrobia	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
CH3_k127_8855666_1	1349785.BAUG01000003_gene251	6.935e-22	105.0	COG3266@1|root,COG3291@1|root,COG4782@1|root,COG4886@1|root,COG3266@2|Bacteria,COG3291@2|Bacteria,COG4782@2|Bacteria,COG4886@2|Bacteria,4PMMS@976|Bacteroidetes,1I661@117743|Flavobacteriia	976|Bacteroidetes	O	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_8855666_2	1304874.JAFY01000001_gene2612	1.969e-19	105.0	COG3210@1|root,COG4447@1|root,COG3210@2|Bacteria,COG4447@2|Bacteria,3TB3U@508458|Synergistetes	508458|Synergistetes	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
CH3_k127_8855666_3	304371.MCP_2796	7.685e-16	93.0	arCOG06738@1|root,arCOG06738@2157|Archaea	2157|Archaea	O	extracellular matrix structural constituent	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	Beta_helix,Calx-beta,CarboxypepD_reg,NosD,Peptidase_S8
CH3_k127_8855666_0	65393.PCC7424_1997	8.887e-32	145.0	COG2931@1|root,COG3210@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,1G4IS@1117|Cyanobacteria,3KKQ9@43988|Cyanothece	1117|Cyanobacteria	QU	PFAM Hemolysin-type calcium-binding region	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,HemolysinCabind
CH3_k127_8874271_0	344747.PM8797T_07534	4.303e-119	393.0	COG1073@1|root,COG1073@2|Bacteria,2IWT8@203682|Planctomycetes	203682|Planctomycetes	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_8895549_0	385682.AFSL01000102_gene55	2.092e-175	558.0	COG0370@1|root,COG0370@2|Bacteria,4NEII@976|Bacteroidetes,2FNKT@200643|Bacteroidia,3XJ70@558415|Marinilabiliaceae	976|Bacteroidetes	P	FeoA	-	-	-	-	-	-	-	-	-	-	-	-	FeoA,FeoB_C,FeoB_N,Gate
CH3_k127_8895549_1	945713.IALB_0510	2.897e-104	349.0	COG0370@1|root,COG0370@2|Bacteria	2|Bacteria	P	ferrous iron transmembrane transporter activity	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
CH3_k127_8895549_2	945713.IALB_0509	2.716e-62	227.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria	2|Bacteria	P	iron ion homeostasis	feoA	-	-	ko:K03322,ko:K03709,ko:K04758	-	-	-	-	ko00000,ko02000,ko03000	2.A.55.2.6,2.A.55.3	-	-	Fe_dep_repr_C,FeoA
CH3_k127_8895549_3	497964.CfE428DRAFT_2157	2.142e-30	122.0	COG3536@1|root,COG3536@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF971)	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	DUF971
CH3_k127_8908558_1	497964.CfE428DRAFT_0568	2.291e-30	121.0	COG0164@1|root,COG0164@2|Bacteria,46SXH@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
CH3_k127_8908558_3	744872.Spica_1041	1.984e-22	109.0	COG2227@1|root,COG2227@2|Bacteria,2J6CB@203691|Spirochaetes	203691|Spirochaetes	H	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
CH3_k127_8908558_4	478741.JAFS01000002_gene94	1.293e-17	89.0	COG0792@1|root,COG0792@2|Bacteria,46ZGA@74201|Verrucomicrobia,37H17@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	L	Uncharacterised protein family UPF0102	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
CH3_k127_8908558_2	1403819.BATR01000167_gene5697	1.91e-29	126.0	COG2453@1|root,COG2453@2|Bacteria,46XSU@74201|Verrucomicrobia,2IWHI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Protein-tyrosine phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	DSPc
CH3_k127_8908558_5	497964.CfE428DRAFT_5371	5.286e-05	53.0	COG4121@1|root,COG4121@2|Bacteria	2|Bacteria	E	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34	mnmC	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0004808,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363	2.1.1.61,2.1.1.72,2.4.2.29,4.2.1.151	ko:K00773,ko:K07319,ko:K11782,ko:K15461	ko00130,ko01110,map00130,map01110	-	R00601,R03789,R08702,R10209,R10666	RC00003,RC00053,RC00060,RC00063,RC01483,RC03232	ko00000,ko00001,ko01000,ko02048,ko03016	-	-	-	DAO,Methyltransf_30
CH3_k127_8908558_0	1122927.KB895429_gene355	7.851e-81	274.0	COG0512@1|root,COG0512@2|Bacteria,1TT9R@1239|Firmicutes,4H9XP@91061|Bacilli,26SGI@186822|Paenibacillaceae	91061|Bacilli	EH	with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine	pabA	-	2.6.1.85,4.1.3.27	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
CH3_k127_8955997_1	1396418.BATQ01000046_gene6147	4.781e-94	317.0	COG1082@1|root,COG1082@2|Bacteria,46WKR@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CH3_k127_8955997_0	1403819.BATR01000191_gene6488	2.519e-185	605.0	COG1199@1|root,COG1199@2|Bacteria,46SCS@74201|Verrucomicrobia,2ITJT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	HELICc2	-	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,Helicase_C_2
CH3_k127_8955997_2	1303518.CCALI_00933	1.273e-12	72.0	COG4537@1|root,COG4537@2|Bacteria	2|Bacteria	U	Required for transformation and DNA binding	comGC	GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944	-	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	M00331,M00429	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
CH3_k127_8970257_0	1244869.H261_07918	5.967e-103	341.0	COG0500@1|root,COG2226@2|Bacteria,1QSZ6@1224|Proteobacteria,2U0WV@28211|Alphaproteobacteria,2JUVE@204441|Rhodospirillales	204441|Rhodospirillales	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CH3_k127_8970257_5	1035191.HMPREF0185_02777	2.209e-50	185.0	COG0110@1|root,COG0110@2|Bacteria,1RFAC@1224|Proteobacteria,2UA7X@28211|Alphaproteobacteria,2KIQ9@204458|Caulobacterales	204458|Caulobacterales	S	Bacterial transferase hexapeptide (six repeats)	-	-	2.3.1.209	ko:K21379	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep
CH3_k127_8970257_2	266264.Rmet_0344	4.241e-79	280.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2VJJ6@28216|Betaproteobacteria,1K0AP@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
CH3_k127_8970257_4	187303.BN69_2092	1.211e-58	213.0	COG2518@1|root,COG2518@2|Bacteria	2|Bacteria	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_12,Methyltransf_23,Methyltransf_25
CH3_k127_8970257_7	1038866.KB902813_gene2087	3.379e-30	126.0	COG0662@1|root,COG0662@2|Bacteria,1QCVX@1224|Proteobacteria,2U0QW@28211|Alphaproteobacteria,3JWFF@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	Cupin 2, conserved barrel domain protein	-	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	-
CH3_k127_8970257_3	1210884.HG799466_gene12608	1.326e-61	217.0	COG0241@1|root,COG0241@2|Bacteria	2|Bacteria	E	D,D-heptose 1,7-bisphosphate phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_like
CH3_k127_8970257_1	1210884.HG799466_gene12607	5.603e-80	274.0	COG1208@1|root,COG1208@2|Bacteria,2J0B4@203682|Planctomycetes	203682|Planctomycetes	JM	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
CH3_k127_8970257_8	288000.BBta_5661	3.61e-28	126.0	COG1216@1|root,COG1216@2|Bacteria,1QW90@1224|Proteobacteria,2U14S@28211|Alphaproteobacteria,3K60W@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CH3_k127_8970257_11	332101.JIBU02000013_gene1351	3.515e-11	78.0	COG1361@1|root,COG1572@1|root,COG2247@1|root,COG2374@1|root,COG3386@1|root,COG4447@1|root,COG5492@1|root,COG1361@2|Bacteria,COG1572@2|Bacteria,COG2247@2|Bacteria,COG2374@2|Bacteria,COG3386@2|Bacteria,COG4447@2|Bacteria,COG5492@2|Bacteria,1V3RT@1239|Firmicutes,25BDG@186801|Clostridia,36WE8@31979|Clostridiaceae	1239|Firmicutes	MN	Carbohydrate binding domain X2	-	-	-	-	-	-	-	-	-	-	-	-	CBM_X2,CW_binding_2,Cadherin-like,Laminin_G_3,SLH
CH3_k127_8970257_10	244447.XP_008310645.1	2.957e-12	81.0	28K45@1|root,2QSIP@2759|Eukaryota,38E3S@33154|Opisthokonta,3BBJ0@33208|Metazoa,3CSD9@33213|Bilateria,4896I@7711|Chordata,48YCX@7742|Vertebrata,49W5A@7898|Actinopterygii	33208|Metazoa	T	Reelin-like	RELN	GO:0000902,GO:0000904,GO:0001101,GO:0001764,GO:0001932,GO:0001934,GO:0001941,GO:0003002,GO:0003008,GO:0003674,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006928,GO:0006935,GO:0006950,GO:0006996,GO:0007154,GO:0007165,GO:0007166,GO:0007275,GO:0007389,GO:0007399,GO:0007409,GO:0007411,GO:0007416,GO:0007417,GO:0007420,GO:0007494,GO:0007610,GO:0007611,GO:0007612,GO:0007613,GO:0007616,GO:0007626,GO:0008104,GO:0008150,GO:0008152,GO:0008306,GO:0008347,GO:0009410,GO:0009605,GO:0009611,GO:0009612,GO:0009628,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009889,GO:0009893,GO:0009966,GO:0009967,GO:0009987,GO:0010001,GO:0010033,GO:0010035,GO:0010038,GO:0010226,GO:0010243,GO:0010468,GO:0010469,GO:0010556,GO:0010562,GO:0010604,GO:0010646,GO:0010647,GO:0010720,GO:0010769,GO:0010770,GO:0010975,GO:0010976,GO:0014066,GO:0014068,GO:0014070,GO:0016043,GO:0016310,GO:0016358,GO:0016477,GO:0017085,GO:0018108,GO:0018193,GO:0018212,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0021510,GO:0021511,GO:0021517,GO:0021536,GO:0021537,GO:0021542,GO:0021543,GO:0021761,GO:0021766,GO:0021769,GO:0021795,GO:0021799,GO:0021800,GO:0021801,GO:0021819,GO:0021854,GO:0021885,GO:0021987,GO:0022008,GO:0022029,GO:0022030,GO:0022603,GO:0022604,GO:0022607,GO:0022898,GO:0023051,GO:0023052,GO:0023056,GO:0030030,GO:0030154,GO:0030182,GO:0030334,GO:0030335,GO:0030424,GO:0030425,GO:0030900,GO:0031012,GO:0031175,GO:0031323,GO:0031325,GO:0031326,GO:0031344,GO:0031346,GO:0031399,GO:0031401,GO:0031503,GO:0031644,GO:0031646,GO:0031960,GO:0032006,GO:0032008,GO:0032268,GO:0032270,GO:0032409,GO:0032411,GO:0032412,GO:0032414,GO:0032501,GO:0032502,GO:0032570,GO:0032793,GO:0032870,GO:0032879,GO:0032989,GO:0032990,GO:0033036,GO:0033555,GO:0033674,GO:0033993,GO:0034613,GO:0034762,GO:0034764,GO:0034765,GO:0034767,GO:0035176,GO:0035295,GO:0035418,GO:0035690,GO:0036211,GO:0036477,GO:0038026,GO:0040011,GO:0040012,GO:0040017,GO:0042063,GO:0042221,GO:0042325,GO:0042327,GO:0042330,GO:0042391,GO:0042493,GO:0042995,GO:0043005,GO:0043025,GO:0043085,GO:0043113,GO:0043170,GO:0043200,GO:0043204,GO:0043269,GO:0043270,GO:0043412,GO:0043549,GO:0044057,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044297,GO:0044421,GO:0044424,GO:0044463,GO:0044464,GO:0045471,GO:0045595,GO:0045597,GO:0045664,GO:0045666,GO:0045859,GO:0045860,GO:0045937,GO:0046677,GO:0048167,GO:0048265,GO:0048468,GO:0048513,GO:0048518,GO:0048522,GO:0048545,GO:0048565,GO:0048583,GO:0048584,GO:0048646,GO:0048666,GO:0048667,GO:0048678,GO:0048699,GO:0048731,GO:0048812,GO:0048814,GO:0048856,GO:0048858,GO:0048869,GO:0048870,GO:0050730,GO:0050731,GO:0050767,GO:0050769,GO:0050773,GO:0050775,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050795,GO:0050803,GO:0050804,GO:0050806,GO:0050807,GO:0050808,GO:0050877,GO:0050890,GO:0050896,GO:0051049,GO:0051050,GO:0051056,GO:0051057,GO:0051090,GO:0051091,GO:0051094,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051252,GO:0051270,GO:0051272,GO:0051338,GO:0051347,GO:0051384,GO:0051385,GO:0051412,GO:0051602,GO:0051641,GO:0051668,GO:0051674,GO:0051703,GO:0051704,GO:0051705,GO:0051716,GO:0051960,GO:0051962,GO:0051966,GO:0051968,GO:0055123,GO:0060255,GO:0060284,GO:0060291,GO:0060322,GO:0060998,GO:0060999,GO:0061001,GO:0061003,GO:0061024,GO:0061097,GO:0061098,GO:0061564,GO:0065007,GO:0065008,GO:0065009,GO:0070325,GO:0070326,GO:0070542,GO:0070727,GO:0070887,GO:0070925,GO:0071310,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071466,GO:0071495,GO:0071548,GO:0071549,GO:0071704,GO:0071840,GO:0072578,GO:0072657,GO:0080090,GO:0090128,GO:0090129,GO:0097106,GO:0097107,GO:0097114,GO:0097119,GO:0097120,GO:0097305,GO:0097327,GO:0097447,GO:0097458,GO:0097475,GO:0097476,GO:0097477,GO:0097485,GO:0098698,GO:0098815,GO:0099068,GO:0099084,GO:0099173,GO:0099175,GO:0099177,GO:0099601,GO:0120025,GO:0120035,GO:0120036,GO:0120038,GO:0120039,GO:1900006,GO:1900271,GO:1900273,GO:1900449,GO:1900451,GO:1901564,GO:1901654,GO:1901655,GO:1901698,GO:1901700,GO:1901701,GO:1902076,GO:1902078,GO:1902531,GO:1902533,GO:1903506,GO:1904062,GO:1904064,GO:1904861,GO:1905483,GO:1905485,GO:2000026,GO:2000112,GO:2000145,GO:2000147,GO:2000273,GO:2000310,GO:2000311,GO:2000463,GO:2000969,GO:2001141,GO:2001222,GO:2001224,GO:2001257,GO:2001259	-	ko:K06249	ko04151,ko04510,ko04512,ko05165,map04151,map04510,map04512,map05165	-	-	-	ko00000,ko00001,ko01000,ko04516	-	-	-	EGF_2,Reeler
CH3_k127_8970257_6	1396141.BATP01000056_gene3278	5.445e-46	193.0	COG0028@1|root,COG3055@1|root,COG3209@1|root,COG4625@1|root,COG4932@1|root,COG0028@2|Bacteria,COG3055@2|Bacteria,COG3209@2|Bacteria,COG4625@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	4.1.3.1	ko:K01637,ko:K20276	ko00630,ko01100,ko01110,ko01120,ko01200,ko02024,map00630,map01100,map01110,map01120,map01200,map02024	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	He_PIG,Laminin_G_3,Malectin
CH3_k127_8970257_9	237368.SCABRO_00978	4.949e-28	134.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	BACON,DUF11,Fil_haemagg_2,Flg_new,PATR
CH3_k127_8978963_1	497964.CfE428DRAFT_4735	3.804e-50	186.0	COG3436@1|root,COG3436@2|Bacteria,46VCT@74201|Verrucomicrobia	74201|Verrucomicrobia	L	IS66 Orf2 like protein	-	-	-	-	-	-	-	-	-	-	-	-	TnpB_IS66
CH3_k127_8978963_2	497964.CfE428DRAFT_4822	4.254e-14	78.0	2B6YR@1|root,2ZVXX@2|Bacteria,46WP9@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_8978963_0	1121468.AUBR01000026_gene2918	1.083e-100	344.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,248MM@186801|Clostridia,42F0T@68295|Thermoanaerobacterales	186801|Clostridia	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
CH3_k127_8978963_3	1189612.A33Q_3002	4.2e-05	52.0	COG2755@1|root,COG2755@2|Bacteria,4NKBE@976|Bacteroidetes,47NHR@768503|Cytophagia	976|Bacteroidetes	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CH3_k127_9052148_4	96561.Dole_1146	3.485e-21	97.0	COG0563@1|root,COG0563@2|Bacteria	2|Bacteria	F	adenylate kinase activity	adk	-	2.7.4.3,6.3.4.4	ko:K00939,ko:K01939	ko00230,ko00250,ko00730,ko01100,ko01110,ko01130,map00230,map00250,map00730,map01100,map01110,map01130	M00049	R00127,R01135,R01547,R11319	RC00002,RC00458,RC00459	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
CH3_k127_9052148_0	478741.JAFS01000001_gene1962	3.775e-169	551.0	COG0568@1|root,COG0568@2|Bacteria,46S6M@74201|Verrucomicrobia,37G93@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
CH3_k127_9052148_2	1396141.BATP01000060_gene4695	3.1e-99	338.0	COG0546@1|root,COG1051@1|root,COG0546@2|Bacteria,COG1051@2|Bacteria,46VY5@74201|Verrucomicrobia,2IUEQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	HAD-hyrolase-like	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2,NUDIX
CH3_k127_9052148_5	1132855.KB913035_gene572	2.284e-14	77.0	COG1539@1|root,COG1539@2|Bacteria,1MZ8Z@1224|Proteobacteria,2VUVV@28216|Betaproteobacteria,2KMXM@206350|Nitrosomonadales	206350|Nitrosomonadales	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	-	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
CH3_k127_9052148_3	1500893.JQNB01000001_gene1609	5.403e-48	177.0	COG2905@1|root,COG2905@2|Bacteria,1QTTR@1224|Proteobacteria,1SBBF@1236|Gammaproteobacteria,1XDAF@135614|Xanthomonadales	135614|Xanthomonadales	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
CH3_k127_9052148_7	864051.BurJ1DRAFT_1395	0.0003976	51.0	2E8G8@1|root,332UI@2|Bacteria,1N7XZ@1224|Proteobacteria,2W3AB@28216|Betaproteobacteria,1KNT8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	PEP-CTERM motif	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
CH3_k127_9052148_6	1303518.CCALI_00340	2.432e-13	79.0	COG4537@1|root,COG4537@2|Bacteria	2|Bacteria	U	Required for transformation and DNA binding	comGC	GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944	-	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	M00331,M00429	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
CH3_k127_9052148_1	861299.J421_6202	4.704e-128	424.0	COG1064@1|root,COG1064@2|Bacteria,1ZSXS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Zinc-binding dehydrogenase	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CH3_k127_9054178_3	926560.KE387023_gene2150	2.696e-31	143.0	COG5184@1|root,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	DUF4347,He_PIG,HemolysinCabind,RCC1_2
CH3_k127_9054178_4	1089547.KB913013_gene3400	6.572e-11	76.0	COG1874@1|root,COG2133@1|root,COG1874@2|Bacteria,COG2133@2|Bacteria,4NIJA@976|Bacteroidetes,47NB2@768503|Cytophagia	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,GSDH,I-set,Ig_3
CH3_k127_9054178_1	234267.Acid_2668	1.001e-111	371.0	COG0407@1|root,COG0407@2|Bacteria,3Y8YA@57723|Acidobacteria	57723|Acidobacteria	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
CH3_k127_9054178_2	404380.Gbem_3420	2.958e-75	259.0	COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,42P3I@68525|delta/epsilon subdivisions,2WM37@28221|Deltaproteobacteria,43TDJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
CH3_k127_9054178_0	794903.OPIT5_02510	1.077e-121	401.0	COG4974@1|root,COG4974@2|Bacteria,46UB9@74201|Verrucomicrobia,3K9DD@414999|Opitutae	414999|Opitutae	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
CH3_k127_905785_8	1303518.CCALI_01258	1.658e-13	79.0	COG4537@1|root,COG4537@2|Bacteria	2|Bacteria	U	Required for transformation and DNA binding	comGC	GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944	-	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	M00331,M00429	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
CH3_k127_905785_2	1210884.HG799469_gene14163	1.673e-121	406.0	COG0666@1|root,COG1520@1|root,COG0666@2|Bacteria,COG1520@2|Bacteria,2J2A4@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
CH3_k127_905785_0	1047013.AQSP01000089_gene1181	5.102e-140	470.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	cyaJ	-	4.6.1.1	ko:K01768,ko:K02483	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	Guanylate_cyc,HTH_18,TPR_16,TPR_19,TPR_2,TPR_8
CH3_k127_905785_3	502025.Hoch_1100	2.159e-80	305.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42PPB@68525|delta/epsilon subdivisions,2X5YN@28221|Deltaproteobacteria,2YUEJ@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_10,TPR_12
CH3_k127_905785_6	66874.JOFS01000006_gene4504	6.977e-44	186.0	COG2319@1|root,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria	201174|Actinobacteria	F	WD-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,WD40
CH3_k127_905785_9	1457250.BBMO01000003_gene3175	1.639e-11	72.0	COG0456@1|root,arCOG00833@2157|Archaea,2Y0NY@28890|Euryarchaeota,23Y3K@183963|Halobacteria	183963|Halobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CH3_k127_905785_7	1163409.UUA_06087	3.802e-21	104.0	COG0697@1|root,COG0697@2|Bacteria,1PXBY@1224|Proteobacteria,1TCXJ@1236|Gammaproteobacteria,1X9UW@135614|Xanthomonadales	135614|Xanthomonadales	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CH3_k127_905785_1	525904.Tter_2133	6.375e-128	419.0	COG0646@1|root,COG0646@2|Bacteria	2|Bacteria	E	methionine synthase	metH	-	2.1.1.13,2.1.1.5	ko:K00544,ko:K00548	ko00260,ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00260,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R02821,R09365	RC00035,RC00113,RC00496,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Pterin_bind,S-methyl_trans
CH3_k127_905785_4	525904.Tter_2139	7.8e-67	239.0	COG1940@1|root,COG1940@2|Bacteria	2|Bacteria	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
CH3_k127_905785_5	760192.Halhy_1187	2.441e-62	223.0	COG0363@1|root,COG0363@2|Bacteria,4NPBJ@976|Bacteroidetes,1IYJE@117747|Sphingobacteriia	976|Bacteroidetes	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	-	-	3.5.99.6	ko:K02080,ko:K02564	ko00052,ko00520,ko01100,map00052,map00520,map01100	-	R00765,R08365	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso
CH3_k127_9065094_1	1120966.AUBU01000005_gene3745	3.273e-106	347.0	COG3119@1|root,COG3119@2|Bacteria,4P13F@976|Bacteroidetes	976|Bacteroidetes	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CH3_k127_9065094_0	521674.Plim_2374	0.0	1458.0	COG3119@1|root,COG3119@2|Bacteria,2J2HN@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase activity	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
CH3_k127_9065094_2	443143.GM18_2869	4.616e-80	268.0	COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria,42M86@68525|delta/epsilon subdivisions,2WIT1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Subunit R is required for both nuclease and ATPase activities, but not for modification	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
CH3_k127_9065094_5	1396418.BATQ01000007_gene1428	8.352e-13	82.0	COG3210@1|root,COG4625@1|root,COG3210@2|Bacteria,COG4625@2|Bacteria,46VHK@74201|Verrucomicrobia,2IW1Y@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	Passenger-associated-transport-repeat	-	-	-	-	-	-	-	-	-	-	-	-	PATR
CH3_k127_9065094_3	443143.GM18_2869	3.982e-78	265.0	COG0610@1|root,COG0610@2|Bacteria,1MU96@1224|Proteobacteria,42M86@68525|delta/epsilon subdivisions,2WIT1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Subunit R is required for both nuclease and ATPase activities, but not for modification	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
CH3_k127_9065094_4	251221.35210706	9.465e-17	81.0	COG3385@1|root,COG3385@2|Bacteria,1G3D9@1117|Cyanobacteria	1117|Cyanobacteria	L	Transposase DNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,Dimer_Tnp_Tn5,Tnp_DNA_bind
CH3_k127_9066159_3	1396141.BATP01000035_gene4002	1.787e-15	83.0	COG3345@1|root,COG3345@2|Bacteria,46XPU@74201|Verrucomicrobia,2IWC9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	Melibiase
CH3_k127_9066159_1	530564.Psta_2754	1.455e-79	290.0	COG2755@1|root,COG2755@2|Bacteria,2IWTR@203682|Planctomycetes	2|Bacteria	E	sialic acid-specific 9-O-acetylesterase	-	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	SASA
CH3_k127_9066159_0	1288963.ADIS_1256	2.001e-198	628.0	COG3408@1|root,COG3408@2|Bacteria,4NIK8@976|Bacteroidetes	976|Bacteroidetes	G	Trehalase	ygjK	-	-	ko:K03931	-	-	-	-	ko00000	-	GH63	-	Trehalase
CH3_k127_9066159_2	272560.BPSS1260	1.119e-33	148.0	2DBEH@1|root,2Z8SD@2|Bacteria,1R5GT@1224|Proteobacteria,2VMJ8@28216|Betaproteobacteria,1KB6Z@119060|Burkholderiaceae	28216|Betaproteobacteria	E	metalloendopeptidase activity	dtmL	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M66
CH3_k127_9066159_4	1515615.HQ41_01300	4.533e-08	55.0	COG3119@1|root,COG3119@2|Bacteria,4NEM3@976|Bacteroidetes,2FMG2@200643|Bacteroidia,22WGH@171551|Porphyromonadaceae	976|Bacteroidetes	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	DUF4976,Sulfatase
CH3_k127_9073420_2	682795.AciX8_3725	1.145e-11	79.0	COG3250@1|root,COG3250@2|Bacteria,3Y3GV@57723|Acidobacteria,2JHVR@204432|Acidobacteriia	204432|Acidobacteriia	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4982,F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_64,Ig_3
CH3_k127_9073420_0	382464.ABSI01000011_gene2601	1.717e-39	171.0	COG2133@1|root,COG2755@1|root,COG4257@1|root,COG4733@1|root,COG5267@1|root,COG2133@2|Bacteria,COG2755@2|Bacteria,COG4257@2|Bacteria,COG4733@2|Bacteria,COG5267@2|Bacteria,46VBR@74201|Verrucomicrobia,2IUWJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	PA14	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,DUF1800,DUF5011,PA14
CH3_k127_9073420_1	1267535.KB906767_gene4118	2.687e-35	137.0	COG0531@1|root,COG0531@2|Bacteria,3Y3GY@57723|Acidobacteria,2JHIT@204432|Acidobacteriia	204432|Acidobacteriia	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease
CH3_k127_90737_3	243233.MCA2757	3.927e-36	141.0	COG0385@1|root,COG0385@2|Bacteria	2|Bacteria	S	bile acid:sodium symporter activity	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
CH3_k127_90737_1	323848.Nmul_A0761	1.507e-168	542.0	COG4992@1|root,COG4992@2|Bacteria,1R6U9@1224|Proteobacteria,2VR1P@28216|Betaproteobacteria,371Z3@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.13	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R00667	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3,PP-binding
CH3_k127_90737_0	478741.JAFS01000001_gene2129	9.884e-192	625.0	COG2217@1|root,COG2217@2|Bacteria,46S9Z@74201|Verrucomicrobia,37FUI@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	P	Heavy-metal-associated domain	copA	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase,YHS
CH3_k127_90737_2	1396141.BATP01000047_gene3937	2.878e-112	370.0	COG0005@1|root,COG0005@2|Bacteria,46UP8@74201|Verrucomicrobia,2ITPF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Phosphorylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PNP_UDP_1
CH3_k127_90737_5	269798.CHU_1143	9.551e-05	44.0	COG2836@1|root,COG2836@2|Bacteria,4NF84@976|Bacteroidetes,47QDS@768503|Cytophagia	976|Bacteroidetes	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2
CH3_k127_9073901_5	1396141.BATP01000005_gene5990	5.533e-42	158.0	COG4185@1|root,COG4185@2|Bacteria,46XSJ@74201|Verrucomicrobia,2IWH1@203494|Verrucomicrobiae	2|Bacteria	S	zeta toxin	-	-	-	-	-	-	-	-	-	-	-	-	Zeta_toxin
CH3_k127_9073901_0	313628.LNTAR_04061	4.525e-86	294.0	COG0552@1|root,COG0552@2|Bacteria	2|Bacteria	U	SRP-dependent cotranslational protein targeting to membrane	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
CH3_k127_9073901_2	1379698.RBG1_1C00001G1246	6.618e-65	235.0	COG0613@1|root,COG0613@2|Bacteria,2NPEX@2323|unclassified Bacteria	2|Bacteria	S	DNA polymerase alpha chain like domain	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
CH3_k127_9073901_6	497964.CfE428DRAFT_4665	7.877e-34	140.0	COG0781@1|root,COG0781@2|Bacteria,46T7V@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
CH3_k127_9073901_4	1396141.BATP01000027_gene1089	3.587e-43	183.0	COG5373@1|root,COG5373@2|Bacteria,46S9T@74201|Verrucomicrobia,2IUWT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Predicted membrane protein (DUF2339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
CH3_k127_9073901_7	717606.PaecuDRAFT_1429	6.187e-23	100.0	COG0721@1|root,COG0721@2|Bacteria,1VEK3@1239|Firmicutes,4HNNA@91061|Bacilli,26ZAP@186822|Paenibacillaceae	91061|Bacilli	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
CH3_k127_9073901_8	278957.ABEA03000086_gene2490	6.586e-12	75.0	COG2165@1|root,COG2165@2|Bacteria,46Y25@74201|Verrucomicrobia,3K8TK@414999|Opitutae	414999|Opitutae	NU	Protein of unknown function (DUF1559)	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CH3_k127_9073901_9	886293.Sinac_0208	2.342e-06	58.0	COG2165@1|root,COG2165@2|Bacteria,2IX5U@203682|Planctomycetes	203682|Planctomycetes	NU	Protein of unknown function (DUF1559)	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CH3_k127_9073901_3	1254432.SCE1572_38245	1.579e-56	226.0	COG1948@1|root,COG5276@1|root,COG4880@2|Bacteria,COG5276@2|Bacteria,1P2CI@1224|Proteobacteria	1224|Proteobacteria	L	Beta propeller domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta_propel
CH3_k127_9073901_1	28377.ENSACAP00000011761	5.43e-86	295.0	KOG3698@1|root,KOG3698@2759|Eukaryota,38D91@33154|Opisthokonta,3BC69@33208|Metazoa,3CUMB@33213|Bilateria,482A4@7711|Chordata,48XU8@7742|Vertebrata	33208|Metazoa	O	Meningioma expressed antigen 5 (hyaluronidase)	MGEA5	GO:0002119,GO:0002164,GO:0002791,GO:0002793,GO:0003254,GO:0003674,GO:0003824,GO:0004402,GO:0004415,GO:0004553,GO:0004563,GO:0004721,GO:0004722,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0006040,GO:0006044,GO:0006073,GO:0006091,GO:0006112,GO:0006139,GO:0006163,GO:0006325,GO:0006464,GO:0006470,GO:0006473,GO:0006475,GO:0006486,GO:0006491,GO:0006493,GO:0006516,GO:0006517,GO:0006605,GO:0006612,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006873,GO:0006874,GO:0006875,GO:0006886,GO:0006996,GO:0007204,GO:0007275,GO:0007568,GO:0007610,GO:0007622,GO:0007623,GO:0007626,GO:0008080,GO:0008104,GO:0008150,GO:0008152,GO:0008219,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009117,GO:0009141,GO:0009144,GO:0009151,GO:0009200,GO:0009215,GO:0009262,GO:0009394,GO:0009719,GO:0009725,GO:0009791,GO:0009889,GO:0009890,GO:0009892,GO:0009893,GO:0009987,GO:0010033,GO:0010468,GO:0010522,GO:0010524,GO:0010556,GO:0010558,GO:0010559,GO:0010561,GO:0010604,GO:0010605,GO:0010612,GO:0010616,GO:0010646,GO:0010647,GO:0010817,GO:0010827,GO:0010828,GO:0010876,GO:0010959,GO:0014070,GO:0014745,GO:0015031,GO:0015833,GO:0015929,GO:0015980,GO:0016043,GO:0016231,GO:0016311,GO:0016407,GO:0016410,GO:0016569,GO:0016570,GO:0016573,GO:0016740,GO:0016746,GO:0016747,GO:0016787,GO:0016788,GO:0016791,GO:0016798,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019219,GO:0019222,GO:0019538,GO:0019637,GO:0019692,GO:0019725,GO:0019915,GO:0023051,GO:0023056,GO:0030003,GO:0030162,GO:0030163,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031341,GO:0031343,GO:0031399,GO:0031400,GO:0032024,GO:0032268,GO:0032269,GO:0032270,GO:0032501,GO:0032502,GO:0032879,GO:0032880,GO:0033036,GO:0033993,GO:0034212,GO:0034613,GO:0034641,GO:0034645,GO:0034762,GO:0034764,GO:0036211,GO:0040024,GO:0042221,GO:0042391,GO:0042578,GO:0042592,GO:0042886,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043243,GO:0043244,GO:0043269,GO:0043270,GO:0043412,GO:0043413,GO:0043502,GO:0043543,GO:0044042,GO:0044057,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044265,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0045475,GO:0045862,GO:0045935,GO:0046060,GO:0046324,GO:0046326,GO:0046483,GO:0046883,GO:0046887,GO:0046907,GO:0048511,GO:0048512,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048545,GO:0048583,GO:0048585,GO:0048856,GO:0048878,GO:0050708,GO:0050714,GO:0050789,GO:0050794,GO:0050796,GO:0050801,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051052,GO:0051054,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051179,GO:0051222,GO:0051223,GO:0051234,GO:0051235,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051248,GO:0051276,GO:0051480,GO:0051641,GO:0051649,GO:0051881,GO:0051900,GO:0051901,GO:0051924,GO:0051928,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0055086,GO:0055114,GO:0060049,GO:0060051,GO:0060123,GO:0060124,GO:0060255,GO:0060341,GO:0061733,GO:0065007,GO:0065008,GO:0070085,GO:0070201,GO:0070265,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072503,GO:0072507,GO:0072521,GO:0072657,GO:0080090,GO:0090087,GO:0090150,GO:0090257,GO:0090276,GO:0090277,GO:0098771,GO:0140096,GO:1901071,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1903018,GO:1903019,GO:1903530,GO:1903532,GO:1904181,GO:1904951,GO:2000112,GO:2000113	2.3.1.48,3.2.1.169	ko:K15719	ko04931,map04931	-	R09672,R09673	RC00059,RC00397,RC00451,RC00746	ko00000,ko00001,ko01000	-	GH84	-	NAGidase
CH3_k127_9134001_0	926550.CLDAP_19940	2.539e-244	780.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
CH3_k127_9134001_4	370438.PTH_0469	1.247e-83	291.0	COG1163@1|root,COG1163@2|Bacteria,1TSAP@1239|Firmicutes,24EEW@186801|Clostridia,260UT@186807|Peptococcaceae	186801|Clostridia	S	TGS domain	-	-	-	ko:K06944	-	-	-	-	ko00000	-	-	-	MMR_HSR1,TGS
CH3_k127_9134001_2	368408.Tpen_1559	1.599e-143	473.0	COG2407@1|root,arCOG01772@2157|Archaea	2157|Archaea	G	L-fucose isomerase and related	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_9134001_3	926569.ANT_25800	1.16e-94	323.0	28KCX@1|root,2Z9ZQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_9134001_6	682795.AciX8_0146	4.43e-06	59.0	COG2730@1|root,COG2730@2|Bacteria,3Y39Q@57723|Acidobacteria,2JI8V@204432|Acidobacteriia	204432|Acidobacteriia	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase
CH3_k127_9134001_1	1123508.JH636439_gene825	8.216e-150	488.0	COG0673@1|root,COG0673@2|Bacteria,2IXRR@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CH3_k127_9134001_5	497964.CfE428DRAFT_4937	4.408e-07	51.0	COG0280@1|root,COG0280@2|Bacteria,46SP5@74201|Verrucomicrobia	74201|Verrucomicrobia	C	PFAM phosphate acetyl butaryl transferase	-	-	2.3.1.8	ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTA_PTB
CH3_k127_9160114_6	243090.RB7928	2.547e-95	342.0	COG0515@1|root,COG1714@1|root,COG0515@2|Bacteria,COG1714@2|Bacteria,2IY76@203682|Planctomycetes	203682|Planctomycetes	KLT	COG0515 Serine threonine protein	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,RDD
CH3_k127_9160114_10	382464.ABSI01000005_gene1380	3.587e-09	68.0	2B7DQ@1|root,320HD@2|Bacteria,46XRQ@74201|Verrucomicrobia,2IWFK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_9160114_8	998088.B565_2515	8.391e-31	126.0	COG2249@1|root,COG2249@2|Bacteria,1MUHN@1224|Proteobacteria,1RU3S@1236|Gammaproteobacteria,1Y501@135624|Aeromonadales	135624|Aeromonadales	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_2
CH3_k127_9160114_4	398512.JQKC01000004_gene5249	1.376e-153	519.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1UIEA@1239|Firmicutes,25EJM@186801|Clostridia,3WI29@541000|Ruminococcaceae	186801|Clostridia	GT	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
CH3_k127_9160114_5	404589.Anae109_0983	9.976e-153	492.0	COG2008@1|root,COG2008@2|Bacteria,1MWCR@1224|Proteobacteria,42NZ7@68525|delta/epsilon subdivisions,2WKSG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde	ltaE	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
CH3_k127_9160114_3	1031288.AXAA01000003_gene1700	8.842e-164	530.0	COG1757@1|root,COG1757@2|Bacteria,1TQ3B@1239|Firmicutes,248WN@186801|Clostridia,36FFK@31979|Clostridiaceae	186801|Clostridia	C	Na H antiporter	-	-	-	ko:K03315	-	-	-	-	ko00000,ko02000	2.A.35	-	-	Na_H_antiporter
CH3_k127_9160114_1	1267535.KB906767_gene3116	8.198e-176	565.0	COG0531@1|root,COG0531@2|Bacteria,3Y3QM@57723|Acidobacteria,2JKYS@204432|Acidobacteriia	204432|Acidobacteriia	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
CH3_k127_9160114_0	468059.AUHA01000006_gene2919	1.484e-196	624.0	COG0531@1|root,COG0531@2|Bacteria,4NDU2@976|Bacteroidetes,1IPK3@117747|Sphingobacteriia	976|Bacteroidetes	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
CH3_k127_9160114_9	530564.Psta_0781	1.923e-17	90.0	COG1309@1|root,COG1309@2|Bacteria,2J1M7@203682|Planctomycetes	203682|Planctomycetes	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CH3_k127_9160114_7	1238182.C882_0258	5.776e-58	220.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,2U2CU@28211|Alphaproteobacteria,2JQW0@204441|Rhodospirillales	204441|Rhodospirillales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
CH3_k127_9160114_2	1123392.AQWL01000002_gene1978	3.026e-174	565.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,1KSKV@119069|Hydrogenophilales	119069|Hydrogenophilales	V	MMPL family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
CH3_k127_917229_6	479435.Kfla_6730	1.34e-30	131.0	2CPKI@1|root,32SJC@2|Bacteria,2IQPS@201174|Actinobacteria,4DS6U@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3137
CH3_k127_917229_3	382464.ABSI01000010_gene3387	4.645e-49	184.0	COG0564@1|root,COG0564@2|Bacteria,46V2B@74201|Verrucomicrobia,2IU67@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	RNA pseudouridylate synthase	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
CH3_k127_917229_1	595460.RRSWK_03709	1.11e-91	328.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,2IYMF@203682|Planctomycetes	203682|Planctomycetes	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
CH3_k127_917229_5	497964.CfE428DRAFT_2131	1.439e-36	147.0	29NX7@1|root,309VB@2|Bacteria,46WPG@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_917229_7	1128421.JAGA01000002_gene1111	2.764e-29	122.0	COG0622@1|root,COG0622@2|Bacteria,2NQ04@2323|unclassified Bacteria	2|Bacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
CH3_k127_917229_4	483219.LILAB_36295	1.421e-44	180.0	COG0204@1|root,COG0204@2|Bacteria,1R72B@1224|Proteobacteria,433XW@68525|delta/epsilon subdivisions,2X411@28221|Deltaproteobacteria,2YXVN@29|Myxococcales	28221|Deltaproteobacteria	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
CH3_k127_917229_2	313628.LNTAR_05744	1.944e-85	301.0	COG0815@1|root,COG0815@2|Bacteria	2|Bacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
CH3_k127_917229_0	204669.Acid345_4052	4.292e-178	571.0	COG0204@1|root,COG0318@1|root,COG0477@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,COG2814@2|Bacteria,3Y4RT@57723|Acidobacteria	57723|Acidobacteria	IQ	Phosphate acyltransferases	-	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase,MFS_1
CH3_k127_9175418_1	583355.Caka_0634	1.547e-13	85.0	COG2273@1|root,COG2273@2|Bacteria	2|Bacteria	G	xyloglucan:xyloglucosyl transferase activity	-	-	3.2.1.178	ko:K20830	-	-	-	-	ko00000,ko01000	-	GH16	-	CBM_2,CBM_4_9,CBM_6,F5_F8_type_C,Glyco_hydro_16,Glyco_hydro_76,Glyco_hydro_81,Laminin_G_3,RicinB_lectin_2
CH3_k127_9175418_0	382464.ABSI01000013_gene1549	2.582e-140	481.0	COG2312@1|root,COG3211@1|root,COG2312@2|Bacteria,COG3211@2|Bacteria,46XD5@74201|Verrucomicrobia,2IVHX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Fn3_assoc,LTD
CH3_k127_9251165_1	1123508.JH636445_gene6496	8.329e-75	267.0	COG5337@1|root,COG5337@2|Bacteria,2IYR8@203682|Planctomycetes	203682|Planctomycetes	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH
CH3_k127_9251165_0	1122176.KB903609_gene5148	3.814e-78	283.0	COG5337@1|root,COG5337@2|Bacteria,4NI4U@976|Bacteroidetes	976|Bacteroidetes	M	COG5337 Spore coat assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
CH3_k127_9322990_2	537007.BLAHAN_05124	3.692e-53	190.0	COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,248ED@186801|Clostridia,3XYI1@572511|Blautia	186801|Clostridia	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
CH3_k127_9322990_1	497964.CfE428DRAFT_1669	5.111e-69	241.0	COG0563@1|root,COG0563@2|Bacteria,46SW4@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK
CH3_k127_9322990_3	452637.Oter_1047	6.925e-41	163.0	COG0583@1|root,COG0583@2|Bacteria,46V82@74201|Verrucomicrobia,3K8TT@414999|Opitutae	414999|Opitutae	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CH3_k127_9322990_4	335543.Sfum_3460	1.136e-08	61.0	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,42V9M@68525|delta/epsilon subdivisions,2WRDW@28221|Deltaproteobacteria,2MQPR@213462|Syntrophobacterales	28221|Deltaproteobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
CH3_k127_9322990_0	1408473.JHXO01000006_gene1023	5.793e-98	331.0	COG3525@1|root,COG3525@2|Bacteria,4NGV2@976|Bacteroidetes,2FP4G@200643|Bacteroidia	976|Bacteroidetes	G	Glycosyl hydrolase family 20, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_20
CH3_k127_9323416_3	237368.SCABRO_02775	6.551e-05	49.0	COG1361@1|root,COG3023@1|root,COG3064@1|root,COG3266@1|root,COG4412@1|root,COG1361@2|Bacteria,COG3023@2|Bacteria,COG3064@2|Bacteria,COG3266@2|Bacteria,COG4412@2|Bacteria,2J4CI@203682|Planctomycetes	203682|Planctomycetes	MV	Ami_2	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2
CH3_k127_9323416_0	278957.ABEA03000182_gene1979	1.236e-15	91.0	COG4968@1|root,COG4968@2|Bacteria,46Z63@74201|Verrucomicrobia,3KA39@414999|Opitutae	414999|Opitutae	NU	Protein of unknown function (DUF1559)	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CH3_k127_9323416_2	1396141.BATP01000024_gene848	1.014e-11	72.0	COG0845@1|root,COG0845@2|Bacteria,46SVD@74201|Verrucomicrobia,2IUGZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Protein of unknown function (DUF3347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3347,HlyD_D23
CH3_k127_9363169_17	1403819.BATR01000021_gene745	1.872e-104	346.0	COG0012@1|root,COG0012@2|Bacteria,46S8D@74201|Verrucomicrobia,2ITV8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
CH3_k127_9363169_16	497964.CfE428DRAFT_0322	8.738e-110	367.0	COG0536@1|root,COG0536@2|Bacteria,46SBS@74201|Verrucomicrobia	74201|Verrucomicrobia	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
CH3_k127_9363169_40	497964.CfE428DRAFT_6605	3.799e-32	127.0	COG0211@1|root,COG0211@2|Bacteria,46T48@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
CH3_k127_9363169_42	1280950.HJO_06350	1.38e-27	115.0	COG0261@1|root,COG3743@1|root,COG0261@2|Bacteria,COG3743@2|Bacteria,1MZEW@1224|Proteobacteria,2UBT3@28211|Alphaproteobacteria,43XSM@69657|Hyphomonadaceae	28211|Alphaproteobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	HHH_5,Ribosomal_L21p
CH3_k127_9363169_44	1396418.BATQ01000110_gene4800	1.134e-24	111.0	2E4YE@1|root,32ZSA@2|Bacteria,46WYD@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_9363169_49	580332.Slit_2744	4.07e-17	87.0	COG3070@1|root,COG3070@2|Bacteria,1PJWV@1224|Proteobacteria,2W88N@28216|Betaproteobacteria,44WJI@713636|Nitrosomonadales	28216|Betaproteobacteria	K	TfoX N-terminal domain	-	-	-	ko:K07343	-	-	-	-	ko00000	-	-	-	TfoX_N
CH3_k127_9363169_15	1070319.CAGGBEG34_190038	2.741e-110	375.0	COG2027@1|root,COG2027@2|Bacteria,1MW40@1224|Proteobacteria,2VH20@28216|Betaproteobacteria,1JZWN@119060|Burkholderiaceae	28216|Betaproteobacteria	M	D-alanyl-d-alanine carboxypeptidase	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
CH3_k127_9363169_61	768066.HELO_3427	6.777e-05	50.0	COG3339@1|root,COG3339@2|Bacteria,1N9BI@1224|Proteobacteria,1SC8Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
CH3_k127_9363169_9	1123508.JH636444_gene5364	2.715e-158	507.0	COG1082@1|root,COG1082@2|Bacteria,2IXRD@203682|Planctomycetes	203682|Planctomycetes	G	Xylose isomerase-like TIM barrel	-	-	5.1.3.22	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R03244	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	AP_endonuc_2
CH3_k127_9363169_7	867903.ThesuDRAFT_01062	1.816e-171	553.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,247W7@186801|Clostridia,3WDC3@538999|Clostridiales incertae sedis	186801|Clostridia	C	PFAM Aldehyde dehydrogenase family	mmsA	-	1.2.1.18,1.2.1.27,1.2.1.3	ko:K00128,ko:K00140	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00562,ko00620,ko00625,ko00640,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00562,map00620,map00625,map00640,map00903,map00981,map01100,map01110,map01120,map01130,map01200	M00013,M00135	R00264,R00631,R00705,R00706,R00710,R00904,R00922,R00935,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00004,RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CH3_k127_9363169_3	452637.Oter_0622	3.862e-225	711.0	COG0160@1|root,COG0160@2|Bacteria,46TE8@74201|Verrucomicrobia,3KA3D@414999|Opitutae	2|Bacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	dgdA	-	2.6.1.19,2.6.1.22	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	APH,Aminotran_3,Peptidase_M23
CH3_k127_9363169_23	1131269.AQVV01000001_gene1323	1.477e-73	263.0	2DRTQ@1|root,32URN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_9363169_19	497964.CfE428DRAFT_5470	1.061e-97	334.0	COG2204@1|root,COG2204@2|Bacteria,46VVS@74201|Verrucomicrobia	74201|Verrucomicrobia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CH3_k127_9363169_4	497964.CfE428DRAFT_5468	4.276e-191	620.0	COG5000@1|root,COG5000@2|Bacteria,46THS@74201|Verrucomicrobia	74201|Verrucomicrobia	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
CH3_k127_9363169_18	382464.ABSI01000020_gene123	7.351e-102	346.0	COG3437@1|root,COG3437@2|Bacteria,46Z3C@74201|Verrucomicrobia,2IUIF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,Response_reg
CH3_k127_9363169_27	402626.Rpic_2975	7.785e-62	231.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VZJ3@28216|Betaproteobacteria,1JZS4@119060|Burkholderiaceae	28216|Betaproteobacteria	T	Histidine kinase	phcS	-	2.7.13.3	ko:K19621	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
CH3_k127_9363169_12	382464.ABSI01000020_gene121	7.562e-121	403.0	COG0500@1|root,COG0500@2|Bacteria,46YTR@74201|Verrucomicrobia,2IU3A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Response_reg
CH3_k127_9363169_30	1458357.BG58_34255	9.907e-58	220.0	COG3659@1|root,COG3659@2|Bacteria,1QMC3@1224|Proteobacteria,2VMG2@28216|Betaproteobacteria,1K0VE@119060|Burkholderiaceae	28216|Betaproteobacteria	M	PFAM Carbohydrate-selective porin OprB	-	-	-	ko:K07267	-	-	-	-	ko00000,ko02000	1.B.19.1	-	-	OprB
CH3_k127_9363169_39	526222.Desal_3013	1.327e-32	141.0	COG2898@1|root,COG2898@2|Bacteria,1N1JA@1224|Proteobacteria	1224|Proteobacteria	S	Uncharacterised conserved protein (DUF2156)	-	-	2.3.2.3	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00726	-	-	ko00000,ko00001,ko00002,ko01000,ko01504	2.A.1.3.37	-	-	DUF2156
CH3_k127_9363169_22	349521.HCH_05076	2.833e-76	266.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	ycjY	GO:0008150,GO:0009987,GO:0051301	-	ko:K01990,ko:K06889	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	DLH,Hydrolase_4,Peptidase_S15
CH3_k127_9363169_34	243231.GSU1004	3.483e-45	178.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,42MC9@68525|delta/epsilon subdivisions,2WIYS@28221|Deltaproteobacteria,43T97@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Nitrogen fixation master sensor histidine kinase, PAS domain-containing	gnfL	-	2.7.13.3	ko:K02668,ko:K07708,ko:K07709	ko02020,map02020	M00497,M00499,M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_8
CH3_k127_9363169_20	240016.ABIZ01000001_gene2650	4.269e-97	344.0	COG1452@1|root,COG1452@2|Bacteria,46SJX@74201|Verrucomicrobia,2ITQV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	-	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	-
CH3_k127_9363169_51	111780.Sta7437_2149	1.855e-16	90.0	2CFCI@1|root,32S1P@2|Bacteria,1G4ST@1117|Cyanobacteria,3VJTA@52604|Pleurocapsales	1117|Cyanobacteria	S	Protein of unknown function (DUF4230)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4230
CH3_k127_9363169_14	1158318.ATXC01000001_gene495	2.821e-118	399.0	COG0113@1|root,COG0113@2|Bacteria,2G3MJ@200783|Aquificae	200783|Aquificae	H	Belongs to the ALAD family	hemB	GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
CH3_k127_9363169_54	290397.Adeh_3650	3.967e-12	73.0	COG1716@1|root,COG2114@1|root,COG1716@2|Bacteria,COG2114@2|Bacteria	2|Bacteria	T	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,BTAD,DUF4242,FHA,Guanylate_cyc,Trans_reg_C
CH3_k127_9363169_10	1403819.BATR01000184_gene6355	5.222e-142	461.0	COG0505@1|root,COG0505@2|Bacteria,46TDX@74201|Verrucomicrobia,2ITTA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Carbamoyl-phosphate synthase small chain, CPSase domain	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
CH3_k127_9363169_35	794903.OPIT5_07630	2.927e-44	166.0	COG0526@1|root,COG0526@2|Bacteria,46SXQ@74201|Verrucomicrobia,3K8IG@414999|Opitutae	414999|Opitutae	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_7
CH3_k127_9363169_8	497964.CfE428DRAFT_2609	1.896e-169	544.0	COG0044@1|root,COG0044@2|Bacteria,46S78@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
CH3_k127_9363169_60	1462527.CCDM010000002_gene685	5.188e-05	48.0	2EG8N@1|root,33A0G@2|Bacteria,1VMHK@1239|Firmicutes,4HSIH@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_9363169_5	518766.Rmar_0899	5.107e-184	594.0	COG0308@1|root,COG0308@2|Bacteria,4NGUB@976|Bacteroidetes,1FIYP@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
CH3_k127_9363169_24	338963.Pcar_1946	4.065e-69	242.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,42PTX@68525|delta/epsilon subdivisions,2WMQW@28221|Deltaproteobacteria,43TY0@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Cytidylyltransferase	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
CH3_k127_9363169_2	497964.CfE428DRAFT_3303	3.968e-235	739.0	COG0504@1|root,COG0504@2|Bacteria,46S8K@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
CH3_k127_9363169_65	1210884.HG799464_gene10719	0.000488	51.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4132,HEAT_2
CH3_k127_9363169_56	1210884.HG799464_gene10957	2.497e-11	75.0	COG1413@1|root,COG1413@2|Bacteria,2J011@203682|Planctomycetes	203682|Planctomycetes	C	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
CH3_k127_9363169_52	1209989.TepiRe1_1613	5.922e-15	77.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,247PC@186801|Clostridia,42EM6@68295|Thermoanaerobacterales	186801|Clostridia	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
CH3_k127_9363169_59	489825.LYNGBM3L_48350	1.164e-06	53.0	COG2405@1|root,COG2405@2|Bacteria,1G725@1117|Cyanobacteria,1HATZ@1150|Oscillatoriales	1117|Cyanobacteria	S	nucleic acid-binding protein	-	-	-	ko:K07066	-	-	-	-	ko00000	-	-	-	DUF3368
CH3_k127_9363169_48	1123277.KB893217_gene4667	4.866e-19	91.0	COG2405@1|root,COG2405@2|Bacteria,4NVKA@976|Bacteroidetes,47X58@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF3368)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3368
CH3_k127_9363169_21	555079.Toce_0685	1.631e-96	332.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,247PC@186801|Clostridia,42EM6@68295|Thermoanaerobacterales	186801|Clostridia	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
CH3_k127_9363169_46	395493.BegalDRAFT_0545	3.625e-21	99.0	COG5652@1|root,COG5652@2|Bacteria,1N1BF@1224|Proteobacteria,1SBGK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
CH3_k127_9363169_0	118168.MC7420_356	0.0	1087.0	COG1505@1|root,COG1505@2|Bacteria,1G1B7@1117|Cyanobacteria,1H87F@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
CH3_k127_9363169_38	1125863.JAFN01000001_gene2910	5.401e-35	143.0	COG1011@1|root,COG1011@2|Bacteria,1NIPN@1224|Proteobacteria	1224|Proteobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
CH3_k127_9363169_33	583355.Caka_1740	1.995e-45	175.0	2CAZH@1|root,2Z7RU@2|Bacteria,46V42@74201|Verrucomicrobia,3K7Z0@414999|Opitutae	414999|Opitutae	C	TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	-
CH3_k127_9363169_1	452637.Oter_0670	0.0	1019.0	COG1053@1|root,COG1053@2|Bacteria,46S7D@74201|Verrucomicrobia,3K754@414999|Opitutae	414999|Opitutae	C	TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
CH3_k127_9363169_13	452637.Oter_0669	7.896e-119	386.0	COG0479@1|root,COG0479@2|Bacteria,46S82@74201|Verrucomicrobia,3K7PU@414999|Opitutae	414999|Opitutae	C	2Fe-2S iron-sulfur cluster binding domain	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_7,Fer4_8
CH3_k127_9363169_37	530564.Psta_0778	4.661e-39	149.0	COG1832@1|root,COG1832@2|Bacteria,2J066@203682|Planctomycetes	203682|Planctomycetes	S	CoA-binding protein	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
CH3_k127_9363169_26	180332.JTGN01000022_gene1511	8.971e-63	229.0	COG0673@1|root,COG0673@2|Bacteria,1TQ72@1239|Firmicutes,24G9W@186801|Clostridia	186801|Clostridia	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CH3_k127_9363169_6	518766.Rmar_1873	1.172e-176	570.0	COG0138@1|root,COG0138@2|Bacteria,4NEZD@976|Bacteroidetes,1FIKP@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	F	AICARFT/IMPCHase bienzyme	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
CH3_k127_9363169_63	191610.CATYP_00200	0.0002279	49.0	COG1716@1|root,COG1716@2|Bacteria,2GNU2@201174|Actinobacteria,22M4R@1653|Corynebacteriaceae	201174|Actinobacteria	T	FHA domain	fhaA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA,Yop-YscD_cpl
CH3_k127_9363169_58	794903.OPIT5_22505	1.179e-07	63.0	COG1596@1|root,COG1596@2|Bacteria,46VQY@74201|Verrucomicrobia,3K89I@414999|Opitutae	414999|Opitutae	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
CH3_k127_9363169_11	497964.CfE428DRAFT_6114	8.039e-125	426.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,46SBB@74201|Verrucomicrobia	74201|Verrucomicrobia	D	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,Wzz
CH3_k127_9363169_64	243233.MCA1174	0.0002558	53.0	COG5338@1|root,COG5338@2|Bacteria,1R56M@1224|Proteobacteria,1S0PC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Putative beta-barrel porin 2	-	-	-	ko:K20920	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	1.B.66.3.1,1.B.66.3.2	-	-	BBP2_2
CH3_k127_9363169_55	794903.OPIT5_05255	9.946e-12	74.0	COG0457@1|root,COG1652@1|root,COG0457@2|Bacteria,COG1652@2|Bacteria,46T8E@74201|Verrucomicrobia,3K82V@414999|Opitutae	414999|Opitutae	S	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
CH3_k127_9363169_43	1236689.MMALV_01900	3.923e-26	114.0	COG2759@1|root,arCOG04538@2157|Archaea,2XTE0@28890|Euryarchaeota,3F2M9@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
CH3_k127_9363169_57	1301100.HG529244_gene2342	3.268e-08	65.0	COG3103@1|root,COG3807@1|root,COG4193@1|root,COG3103@2|Bacteria,COG3807@2|Bacteria,COG4193@2|Bacteria,COG4991@2|Bacteria,1V0NC@1239|Firmicutes,25BAR@186801|Clostridia,36WMT@31979|Clostridiaceae	186801|Clostridia	GT	Src homology 3 domains	-	-	-	-	-	-	-	-	-	-	-	-	Glucosaminidase,SH3_3
CH3_k127_9363169_29	1122130.AUHN01000008_gene1512	1.493e-59	214.0	COG1187@1|root,COG1187@2|Bacteria,2GJ4N@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the pseudouridine synthase RsuA family	rluB	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.19,5.4.99.22	ko:K06178,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
CH3_k127_9363169_50	382464.ABSI01000005_gene1327	6.739e-17	81.0	2DSQH@1|root,33H1Z@2|Bacteria,46TBQ@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_9363169_32	497964.CfE428DRAFT_0485	1.222e-46	169.0	COG0051@1|root,COG0051@2|Bacteria,46SVV@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
CH3_k127_9363169_28	1121381.JNIV01000084_gene822	4e-61	218.0	COG0087@1|root,COG0087@2|Bacteria,1WI2F@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
CH3_k127_9363169_31	1089553.Tph_c25840	6.109e-49	182.0	COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,42ERX@68295|Thermoanaerobacterales	186801|Clostridia	J	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
CH3_k127_9363169_47	497964.CfE428DRAFT_0488	1.353e-19	91.0	COG0089@1|root,COG0089@2|Bacteria,46WBX@74201|Verrucomicrobia	74201|Verrucomicrobia	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
CH3_k127_9363169_62	102129.Lepto7375DRAFT_0067	9.822e-05	47.0	298NA@1|root,2ZVSW@2|Bacteria	2|Bacteria	K	Cro/C1-type HTH DNA-binding domain	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	-
CH3_k127_9363169_25	765420.OSCT_3130	1.128e-65	258.0	COG4932@1|root,COG5184@1|root,COG4932@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	ychO	GO:0005575,GO:0005623,GO:0008150,GO:0009279,GO:0009405,GO:0016020,GO:0019867,GO:0030260,GO:0030312,GO:0030313,GO:0031975,GO:0044403,GO:0044409,GO:0044419,GO:0044462,GO:0044464,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0071944	3.2.1.14	ko:K01183,ko:K20276	ko00520,ko01100,ko02024,map00520,map01100,map02024	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	He_PIG,IAT_beta,RCC1_2
CH3_k127_9363169_36	1089547.KB913013_gene1006	5.547e-41	155.0	COG0251@1|root,COG0251@2|Bacteria,4NR3V@976|Bacteroidetes,47QRJ@768503|Cytophagia	976|Bacteroidetes	J	Endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
CH3_k127_9363169_41	265729.GS18_0220400	1.732e-29	123.0	2DSM2@1|root,33GKP@2|Bacteria,1VKZ8@1239|Firmicutes,4HSD9@91061|Bacilli,1ZJS2@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4259
CH3_k127_9408870_0	886293.Sinac_0430	0.0	1340.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,2IXGT@203682|Planctomycetes	203682|Planctomycetes	C	heme-binding domain, Pirellula Verrucomicrobium type	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DUF1080
CH3_k127_9413323_2	335543.Sfum_0581	2.565e-100	348.0	COG2202@1|root,COG2984@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2984@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,HATPase_c,HisKA,PAS_3
CH3_k127_9413323_4	443598.AUFA01000003_gene2204	2.074e-59	214.0	COG4566@1|root,COG4566@2|Bacteria,1R47Z@1224|Proteobacteria,2TSQS@28211|Alphaproteobacteria,3JQPG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CH3_k127_9413323_6	1380391.JIAS01000012_gene4181	7.406e-22	100.0	COG4566@1|root,COG4566@2|Bacteria,1N5R5@1224|Proteobacteria,2UE41@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CH3_k127_9413323_3	382464.ABSI01000012_gene2160	3.892e-66	241.0	COG2831@1|root,COG2831@2|Bacteria,46TZZ@74201|Verrucomicrobia	74201|Verrucomicrobia	U	Protein of unknown function (DUF3570)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3570
CH3_k127_9413323_1	452637.Oter_1611	4.59e-109	364.0	COG1477@1|root,COG1477@2|Bacteria,46V6N@74201|Verrucomicrobia,3K9VB@414999|Opitutae	414999|Opitutae	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
CH3_k127_9413323_5	452637.Oter_1612	2.247e-38	150.0	COG0526@1|root,COG0526@2|Bacteria,46W0W@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Redoxin
CH3_k127_9413323_7	452637.Oter_1613	8.89e-19	87.0	2BFNH@1|root,329GX@2|Bacteria,46WJ5@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF4266)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4266
CH3_k127_9413323_0	933262.AXAM01000098_gene3457	7.732e-124	416.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,42MVQ@68525|delta/epsilon subdivisions,2WMS6@28221|Deltaproteobacteria,2MNJX@213118|Desulfobacterales	28221|Deltaproteobacteria	CO	Cytochrome C biogenesis protein transmembrane region	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
CH3_k127_9413323_8	498761.HM1_0137	1.022e-14	83.0	COG1470@1|root,COG3210@1|root,COG4733@1|root,COG4886@1|root,COG5492@1|root,COG1470@2|Bacteria,COG3210@2|Bacteria,COG4733@2|Bacteria,COG4886@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_2,CHU_C,Flg_new,LRR_5,RCC1,SLH
CH3_k127_9418630_4	314230.DSM3645_21427	5.178e-109	368.0	COG1387@1|root,COG2755@1|root,COG1387@2|Bacteria,COG2755@2|Bacteria,2IXFZ@203682|Planctomycetes	203682|Planctomycetes	E	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CH3_k127_9418630_2	240292.Ava_0681	4.698e-144	465.0	COG0667@1|root,COG0667@2|Bacteria,1G3RI@1117|Cyanobacteria,1HMNR@1161|Nostocales	1117|Cyanobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CH3_k127_9418630_0	1122176.KB903544_gene705	7.581e-151	489.0	COG0174@1|root,COG0174@2|Bacteria,4NHET@976|Bacteroidetes,1IPJ3@117747|Sphingobacteriia	976|Bacteroidetes	E	Glutamine synthetase, catalytic domain	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
CH3_k127_9418630_1	395961.Cyan7425_1966	1.303e-150	490.0	COG1012@1|root,COG1012@2|Bacteria,1G1BD@1117|Cyanobacteria,3KGCF@43988|Cyanothece	1117|Cyanobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.39,1.2.1.79,1.2.1.8	ko:K00128,ko:K00130,ko:K00135,ko:K00138,ko:K00146	ko00010,ko00053,ko00071,ko00250,ko00260,ko00280,ko00310,ko00330,ko00340,ko00350,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00650,ko00760,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00250,map00260,map00280,map00310,map00330,map00340,map00350,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00650,map00760,map00903,map00981,map01100,map01110,map01120,map01130	M00027,M00135,M00555	R00264,R00631,R00710,R00711,R00713,R00714,R00904,R01752,R01986,R02401,R02536,R02549,R02565,R02566,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CH3_k127_9418630_7	478741.JAFS01000001_gene1530	9.861e-20	91.0	COG2127@1|root,COG2127@2|Bacteria,46T8N@74201|Verrucomicrobia,37GW2@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
CH3_k127_9418630_5	1156937.MFUM_270019	8.007e-83	280.0	COG2360@1|root,COG2360@2|Bacteria,46VHR@74201|Verrucomicrobia,37GDI@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
CH3_k127_9418630_3	530564.Psta_0851	2.302e-128	418.0	COG0604@1|root,COG0604@2|Bacteria,2IXUI@203682|Planctomycetes	203682|Planctomycetes	C	COG0604 NADPH quinone reductase and related Zn-dependent	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
CH3_k127_9418630_6	1123508.JH636440_gene2839	2.287e-38	149.0	COG2304@1|root,COG2304@2|Bacteria,2IYXD@203682|Planctomycetes	203682|Planctomycetes	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA
CH3_k127_94287_11	497964.CfE428DRAFT_5026	1.378e-07	59.0	2DXTF@1|root,346G5@2|Bacteria,46W16@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_94287_10	756272.Plabr_3146	4.739e-15	80.0	COG5492@1|root,COG5492@2|Bacteria,2IYV9@203682|Planctomycetes	203682|Planctomycetes	N	Domain of unknown function (DUF5060)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF5060
CH3_k127_94287_0	497964.CfE428DRAFT_4943	8.428e-238	781.0	COG0577@1|root,COG0577@2|Bacteria,46U6N@74201|Verrucomicrobia	74201|Verrucomicrobia	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
CH3_k127_94287_4	497964.CfE428DRAFT_4944	2.342e-71	251.0	COG1136@1|root,COG1136@2|Bacteria,46V6W@74201|Verrucomicrobia	74201|Verrucomicrobia	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
CH3_k127_94287_2	497964.CfE428DRAFT_5490	9.614e-116	382.0	COG0524@1|root,COG0524@2|Bacteria,46SCP@74201|Verrucomicrobia	74201|Verrucomicrobia	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
CH3_k127_94287_7	1279038.KB907348_gene3100	1.171e-39	156.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2TR2B@28211|Alphaproteobacteria,2JQWU@204441|Rhodospirillales	204441|Rhodospirillales	O	COG0790 FOG TPR repeat, SEL1 subfamily	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
CH3_k127_94287_5	497964.CfE428DRAFT_3924	7.857e-64	224.0	COG0231@1|root,COG0231@2|Bacteria,46SQH@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
CH3_k127_94287_8	469383.Cwoe_4636	4.092e-21	100.0	COG0254@1|root,COG0254@2|Bacteria,2IQ4I@201174|Actinobacteria,4CQSQ@84995|Rubrobacteria	84995|Rubrobacteria	J	Ribosomal protein L31	rpmE2	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
CH3_k127_94287_1	452637.Oter_3498	2.619e-135	439.0	COG0216@1|root,COG0216@2|Bacteria,46S6F@74201|Verrucomicrobia,3K794@414999|Opitutae	414999|Opitutae	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
CH3_k127_94287_6	314230.DSM3645_05160	1.75e-55	200.0	COG0637@1|root,COG0637@2|Bacteria,2IZIM@203682|Planctomycetes	203682|Planctomycetes	S	TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
CH3_k127_94287_9	589865.DaAHT2_0949	3.361e-16	81.0	COG0296@1|root,COG0296@2|Bacteria,1NIZI@1224|Proteobacteria,42WYM@68525|delta/epsilon subdivisions,2WSNX@28221|Deltaproteobacteria,2MMER@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Glycogen recognition site of AMP-activated protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM
CH3_k127_94287_3	382464.ABSI01000013_gene1799	3.642e-105	357.0	COG2239@1|root,COG2239@2|Bacteria,46S6D@74201|Verrucomicrobia,2IU82@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Divalent cation transporter	-	-	-	-	-	-	-	-	-	-	-	-	CBS,MgtE,MgtE_N
CH3_k127_9437969_6	1120965.AUBV01000006_gene2184	9.281e-32	130.0	28H8R@1|root,2Z7KJ@2|Bacteria,4NGZN@976|Bacteroidetes,47NH9@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_9437969_1	1210884.HG799469_gene14163	4.832e-122	407.0	COG0666@1|root,COG1520@1|root,COG0666@2|Bacteria,COG1520@2|Bacteria,2J2A4@203682|Planctomycetes	203682|Planctomycetes	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
CH3_k127_9437969_7	96561.Dole_2048	6.012e-31	133.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,42Q3J@68525|delta/epsilon subdivisions,2WP5U@28221|Deltaproteobacteria,2MKDQ@213118|Desulfobacterales	28221|Deltaproteobacteria	M	TIGRFAM YD repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat,YwqJ-deaminase
CH3_k127_9437969_4	880072.Desac_0729	1.246e-59	226.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,42ND6@68525|delta/epsilon subdivisions,2WIJS@28221|Deltaproteobacteria,2MQB5@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
CH3_k127_9437969_3	1469245.JFBG01000044_gene1864	2.564e-60	218.0	COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,1RMX5@1236|Gammaproteobacteria,1WYE1@135613|Chromatiales	135613|Chromatiales	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
CH3_k127_9437969_0	639030.JHVA01000001_gene2781	5.512e-173	555.0	COG0673@1|root,COG0673@2|Bacteria,3Y6C9@57723|Acidobacteria,2JKU9@204432|Acidobacteriia	204432|Acidobacteriia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CH3_k127_9437969_8	290397.Adeh_1033	7.634e-23	107.0	COG0705@1|root,COG0705@2|Bacteria	2|Bacteria	S	proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
CH3_k127_9437969_2	225849.swp_0274	1.642e-83	287.0	2910Q@1|root,2ZNNC@2|Bacteria,1PCP3@1224|Proteobacteria,1S0BX@1236|Gammaproteobacteria,2Q953@267890|Shewanellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_9437969_5	1395513.P343_05500	4.342e-51	188.0	COG1704@1|root,COG1704@2|Bacteria,1V3R9@1239|Firmicutes,4IR1H@91061|Bacilli,26PKG@186821|Sporolactobacillaceae	91061|Bacilli	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
CH3_k127_9437969_9	1304865.JAGF01000001_gene984	8.713e-08	57.0	292NE@1|root,2ZQ69@2|Bacteria,2I8AI@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_945024_15	497964.CfE428DRAFT_4678	1.207e-11	69.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	ko:K13735	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	Beta_helix,Big_2,CarboxypepD_reg,He_PIG,LysM,PSII_BNR,SLH,TIG,fn3
CH3_k127_945024_12	1396141.BATP01000002_gene4848	7.265e-23	103.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,GSDH,Laminin_G_3,PA14
CH3_k127_945024_6	478741.JAFS01000001_gene1963	3.678e-107	369.0	COG0358@1|root,COG0358@2|Bacteria,46S6C@74201|Verrucomicrobia,37GA0@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_N,zf-CHC2
CH3_k127_945024_16	111781.Lepto7376_2051	1.804e-07	64.0	COG0457@1|root,COG0457@2|Bacteria,1G39E@1117|Cyanobacteria,1H8XZ@1150|Oscillatoriales	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_2,TPR_8
CH3_k127_945024_14	1121405.dsmv_3253	3.536e-12	79.0	COG0457@1|root,COG0457@2|Bacteria,1MZGK@1224|Proteobacteria,42US4@68525|delta/epsilon subdivisions,2X72T@28221|Deltaproteobacteria,2MPJC@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Tetratricopeptide TPR_2	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
CH3_k127_945024_13	880073.Calab_0868	3.686e-15	87.0	COG2006@1|root,COG2006@2|Bacteria,2NPI6@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
CH3_k127_945024_0	575540.Isop_0569	1.264e-205	645.0	COG0673@1|root,COG0673@2|Bacteria,2IWTD@203682|Planctomycetes	203682|Planctomycetes	S	PFAM oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CH3_k127_945024_17	1452536.JARE01000052_gene1721	0.0002819	51.0	2EH4F@1|root,33AWE@2|Bacteria,2I6EJ@201174|Actinobacteria,4FTHX@85023|Microbacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_945024_4	344747.PM8797T_17402	4.904e-155	499.0	COG1082@1|root,COG1082@2|Bacteria,2IY10@203682|Planctomycetes	203682|Planctomycetes	G	PFAM Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CH3_k127_945024_5	497964.CfE428DRAFT_0899	1.372e-127	419.0	COG0820@1|root,COG0820@2|Bacteria,46SBD@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
CH3_k127_945024_10	1123376.AUIU01000011_gene924	1.047e-62	222.0	COG0118@1|root,COG0118@2|Bacteria,3J0K7@40117|Nitrospirae	40117|Nitrospirae	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
CH3_k127_945024_8	497964.CfE428DRAFT_1492	5.613e-90	300.0	COG0605@1|root,COG0605@2|Bacteria,46SQF@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
CH3_k127_945024_1	497964.CfE428DRAFT_2099	1.669e-201	647.0	COG0488@1|root,COG0488@2|Bacteria,46UUC@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM ABC transporter related	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
CH3_k127_945024_11	886293.Sinac_0868	1.738e-37	148.0	COG5507@1|root,COG5507@2|Bacteria,2J071@203682|Planctomycetes	203682|Planctomycetes	S	NIPSNAP family containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NIPSNAP
CH3_k127_945024_2	478741.JAFS01000002_gene116	5.172e-168	548.0	COG1190@1|root,COG1190@2|Bacteria,46TIA@74201|Verrucomicrobia,37FUW@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	J	tRNA synthetases class II (D, K and N)	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
CH3_k127_945024_3	240016.ABIZ01000001_gene2258	1.823e-155	495.0	COG5564@1|root,COG5564@2|Bacteria,46TKF@74201|Verrucomicrobia,2IVH6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Phosphoenolpyruvate hydrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	PEP_hydrolase
CH3_k127_945024_9	1403819.BATR01000098_gene3285	1.565e-67	232.0	COG1917@1|root,COG1917@2|Bacteria,46WE0@74201|Verrucomicrobia,2IVZR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CH3_k127_945024_7	240016.ABIZ01000001_gene2256	7.234e-93	327.0	COG1413@1|root,COG2133@1|root,COG3828@1|root,COG1413@2|Bacteria,COG2133@2|Bacteria,COG3828@2|Bacteria,46XAM@74201|Verrucomicrobia,2IV7A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CG	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,ThuA
CH3_k127_9481228_2	1396418.BATQ01000024_gene5207	5.019e-13	72.0	COG0156@1|root,COG0156@2|Bacteria,46TTU@74201|Verrucomicrobia,2ITJB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Aminotransferase class I and II	-	-	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CH3_k127_9481228_0	207559.Dde_2656	4.515e-122	409.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,42MFC@68525|delta/epsilon subdivisions,2WJ4H@28221|Deltaproteobacteria,2MA1I@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	AAA_26,Aminotran_3
CH3_k127_9481228_1	477974.Daud_1570	3.832e-105	367.0	COG4147@1|root,COG4147@2|Bacteria,1V2SK@1239|Firmicutes,25DGS@186801|Clostridia,264G7@186807|Peptococcaceae	186801|Clostridia	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
CH3_k127_9494073_4	443143.GM18_2872	9.904e-39	151.0	COG0286@1|root,COG0286@2|Bacteria,1MW3A@1224|Proteobacteria,42N9K@68525|delta/epsilon subdivisions,2WINH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	PFAM N-6 DNA methylase	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
CH3_k127_9494073_7	290317.Cpha266_1712	0.0002689	46.0	COG0286@1|root,COG0286@2|Bacteria	2|Bacteria	V	site-specific DNA-methyltransferase (adenine-specific) activity	hsdM	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
CH3_k127_9494073_6	403833.Pmob_1240	1.638e-17	84.0	COG1724@1|root,COG1724@2|Bacteria	2|Bacteria	N	mRNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
CH3_k127_9494073_5	1173029.JH980292_gene2834	4.942e-29	117.0	COG1598@1|root,COG1598@2|Bacteria,1G7N4@1117|Cyanobacteria,1HDCI@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
CH3_k127_9494073_2	314230.DSM3645_14120	3.789e-86	293.0	COG1082@1|root,COG1082@2|Bacteria,2IXNX@203682|Planctomycetes	203682|Planctomycetes	G	COG1082 Sugar phosphate	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
CH3_k127_9494073_0	1254432.SCE1572_17235	0.0	1227.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
CH3_k127_9494073_3	1254432.SCE1572_17230	2.54e-55	207.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
CH3_k127_9494073_1	1379698.RBG1_1C00001G1725	1.924e-101	348.0	COG0841@1|root,COG0841@2|Bacteria,2NNUH@2323|unclassified Bacteria	2|Bacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	acrD	-	-	ko:K03296,ko:K18138,ko:K18307	ko01501,ko01503,ko02024,map01501,map01503,map02024	M00644,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2,2.A.6.2.20,2.A.6.2.32	-	-	ACR_tran
CH3_k127_9520899_4	760568.Desku_0794	1.568e-39	157.0	COG3547@1|root,COG3547@2|Bacteria,1V0B6@1239|Firmicutes,248VY@186801|Clostridia,264BH@186807|Peptococcaceae	186801|Clostridia	L	PFAM Transposase, IS111A IS1328 IS1533	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
CH3_k127_9520899_7	710696.Intca_0033	9.776e-12	71.0	COG3547@1|root,COG3547@2|Bacteria,2GNQB@201174|Actinobacteria,4FG97@85021|Intrasporangiaceae	201174|Actinobacteria	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
CH3_k127_9520899_1	330214.NIDE0545	3.293e-60	239.0	COG0745@1|root,COG2202@1|root,COG3290@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG3290@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GGDEF,HATPase_c,PAS,PAS_3,PAS_4,PAS_9,Response_reg,SpoIIE,dCache_1
CH3_k127_9520899_5	794903.OPIT5_22540	2.599e-39	171.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07683	ko02020,map02020	M00483	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HATPase_c_2,HisKA_3,PAS,PAS_4,PAS_9
CH3_k127_9520899_3	909663.KI867150_gene1086	4.185e-52	192.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42N8J@68525|delta/epsilon subdivisions,2WK63@28221|Deltaproteobacteria,2MRGY@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CH3_k127_9520899_6	1123242.JH636434_gene5272	6.69e-15	78.0	COG1621@1|root,COG1621@2|Bacteria,2IY26@203682|Planctomycetes	2|Bacteria	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Dockerin_1,HTH_18,RicinB_lectin_2
CH3_k127_9520899_2	240016.ABIZ01000001_gene3538	1.148e-56	224.0	COG2755@1|root,COG2755@2|Bacteria,46WAY@74201|Verrucomicrobia	74201|Verrucomicrobia	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_9520899_0	1203550.HMPREF1475_00695	1.617e-101	360.0	COG3533@1|root,COG3533@2|Bacteria,4NG7T@976|Bacteroidetes,2FPXE@200643|Bacteroidia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_127
CH3_k127_9540636_1	504472.Slin_3038	8.907e-29	124.0	COG4636@1|root,COG4636@2|Bacteria,4NFKR@976|Bacteroidetes,47K44@768503|Cytophagia	976|Bacteroidetes	S	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
CH3_k127_9540636_0	861299.J421_1753	4.721e-220	720.0	COG0446@1|root,COG4888@1|root,COG0446@2|Bacteria,COG4888@2|Bacteria	2|Bacteria	G	ASPIC UnbV domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,Pyr_redox_2,UnbV_ASPIC,VCBS
CH3_k127_9559848_4	1403819.BATR01000112_gene3806	1.758e-46	173.0	COG0659@1|root,COG0659@2|Bacteria	2|Bacteria	P	secondary active sulfate transmembrane transporter activity	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
CH3_k127_9559848_0	1304885.AUEY01000019_gene1169	4.907e-143	477.0	COG1075@1|root,COG1075@2|Bacteria,1NYAK@1224|Proteobacteria,42Q3C@68525|delta/epsilon subdivisions,2WMAK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
CH3_k127_9559848_1	497964.CfE428DRAFT_5778	3.849e-105	351.0	28HK0@1|root,2Z7V0@2|Bacteria,46TSH@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
CH3_k127_9559848_6	247639.MGP2080_02111	3.519e-31	132.0	COG2067@1|root,COG2067@2|Bacteria,1NDQA@1224|Proteobacteria,1TIWZ@1236|Gammaproteobacteria,1JBA2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_9559848_8	1500281.JQKZ01000022_gene837	0.0005687	52.0	COG3637@1|root,COG3637@2|Bacteria,4PKKK@976|Bacteroidetes,1HYEJ@117743|Flavobacteriia,3ZP50@59732|Chryseobacterium	976|Bacteroidetes	M	Protein of unknown function (DUF2490)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2490
CH3_k127_9559848_5	1123368.AUIS01000004_gene187	5.165e-35	145.0	arCOG10317@1|root,2Z7VW@2|Bacteria,1RGUS@1224|Proteobacteria,1S5VW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_9559848_7	1097668.BYI23_C012290	1.796e-22	102.0	COG2149@1|root,COG2149@2|Bacteria,1N8RW@1224|Proteobacteria,2VYKE@28216|Betaproteobacteria,1K9CA@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF202)	-	-	-	ko:K00389	-	-	-	-	ko00000	-	-	-	DUF202
CH3_k127_9559848_2	247490.KSU1_C0461	5.627e-66	240.0	COG1775@1|root,COG1924@1|root,COG1775@2|Bacteria,COG1924@2|Bacteria,2J22H@203682|Planctomycetes	203682|Planctomycetes	EI	2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,HGD-D
CH3_k127_9559848_3	1443122.Z958_01335	7.179e-64	228.0	COG1924@1|root,COG1924@2|Bacteria,1TQSD@1239|Firmicutes,2481W@186801|Clostridia,36F30@31979|Clostridiaceae	186801|Clostridia	I	CoA-substrate-specific enzyme activase	fldI	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
CH3_k127_9578968_4	290397.Adeh_3087	3.841e-86	294.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42QZ2@68525|delta/epsilon subdivisions,2WMS4@28221|Deltaproteobacteria,2Z16M@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	cbcT	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_11,Fer4_2,Fer4_3,Fer4_7
CH3_k127_9578968_2	1379698.RBG1_1C00001G0297	8.387e-124	409.0	COG4881@1|root,COG4881@2|Bacteria	2|Bacteria	-	-	cbcU	-	-	-	-	-	-	-	-	-	-	-	NrfD
CH3_k127_9578968_6	1121920.AUAU01000009_gene1858	3.049e-22	105.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
CH3_k127_9578968_3	1125863.JAFN01000001_gene561	2.645e-109	363.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,43AKQ@68525|delta/epsilon subdivisions,2X60P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM 4Fe-4S	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11,Fer4_4
CH3_k127_9578968_1	1396141.BATP01000019_gene1673	1.064e-127	428.0	COG5557@1|root,COG5557@2|Bacteria,46U15@74201|Verrucomicrobia,2ITS8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
CH3_k127_9578968_7	452637.Oter_3126	6.819e-18	90.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	ccoP	-	-	ko:K00406,ko:K08906	ko00190,ko00195,ko01100,ko02020,map00190,map00195,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko00194	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
CH3_k127_9578968_0	452637.Oter_2584	1.833e-154	502.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114	-	ko:K15876	ko00910,ko01120,map00910,map01120	M00530	R05712	RC00176	ko00000,ko00001,ko00002	-	-	-	Cytochrom_NNT,Cytochrom_c3_2
CH3_k127_9578968_5	1121920.AUAU01000001_gene2269	3.616e-72	250.0	COG2864@1|root,COG2864@2|Bacteria,3Y6QW@57723|Acidobacteria	2|Bacteria	C	Prokaryotic cytochrome b561	cbcY	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Cytochrome_C7,Ni_hydr_CYTB,Paired_CXXCH_1,Rhodanese
CH3_k127_9579882_19	983545.Glaag_0266	5.847e-10	61.0	COG0115@1|root,COG0115@2|Bacteria,1MVAT@1224|Proteobacteria,1RPU0@1236|Gammaproteobacteria,464SW@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase	dat	-	2.6.1.21	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	-	R01148,R01582,R02459,R02851,R02924,R05053	RC00006,RC00008,RC00025	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4
CH3_k127_9579882_5	1423321.AS29_17875	1.442e-85	290.0	COG1692@1|root,COG1692@2|Bacteria,1TR9P@1239|Firmicutes,4HAV5@91061|Bacilli,1ZC3D@1386|Bacillus	91061|Bacilli	S	protein conserved in bacteria	ymdB	GO:0003674,GO:0003824,GO:0004112,GO:0004113,GO:0008081,GO:0016787,GO:0016788,GO:0042578	-	ko:K02029,ko:K02030,ko:K09769	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	YmdB
CH3_k127_9579882_11	497964.CfE428DRAFT_4603	2.623e-74	265.0	COG0349@1|root,COG0349@2|Bacteria,46SUU@74201|Verrucomicrobia	74201|Verrucomicrobia	L	3'-5' exonuclease	rnd	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
CH3_k127_9579882_0	530564.Psta_1928	4.409e-260	834.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,2IWYB@203682|Planctomycetes	203682|Planctomycetes	C	heme-binding domain, Pirellula Verrucomicrobium type	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
CH3_k127_9579882_1	497964.CfE428DRAFT_0815	9.767e-246	766.0	COG1482@1|root,COG1482@2|Bacteria,46VQS@74201|Verrucomicrobia	74201|Verrucomicrobia	G	cell wall glycoprotein biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_9579882_18	1122939.ATUD01000005_gene2726	1.862e-14	87.0	COG4402@1|root,COG4402@2|Bacteria,2I90K@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2330
CH3_k127_9579882_21	66875.JODY01000030_gene3928	4.622e-06	58.0	COG0789@1|root,COG1413@1|root,COG0789@2|Bacteria,COG1413@2|Bacteria,2GMKH@201174|Actinobacteria	201174|Actinobacteria	CK	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,MerR,MerR_1
CH3_k127_9579882_17	240016.ABIZ01000001_gene2350	1.437e-31	126.0	COG0724@1|root,COG0724@2|Bacteria,46VMU@74201|Verrucomicrobia,2IUHZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
CH3_k127_9579882_16	1396418.BATQ01000106_gene5306	6.85e-43	173.0	2DTXG@1|root,33N3G@2|Bacteria,46WXU@74201|Verrucomicrobia,2IVTG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
CH3_k127_9579882_3	1121405.dsmv_1085	1.598e-124	422.0	COG3225@1|root,COG3225@2|Bacteria,1MY63@1224|Proteobacteria,42N95@68525|delta/epsilon subdivisions,2WJ0N@28221|Deltaproteobacteria,2MJFD@213118|Desulfobacterales	28221|Deltaproteobacteria	N	ABC-type uncharacterized transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
CH3_k127_9579882_7	1123073.KB899242_gene1477	2.589e-82	284.0	COG1277@1|root,COG1277@2|Bacteria,1NZZ9@1224|Proteobacteria,1RP6C@1236|Gammaproteobacteria,1X35D@135614|Xanthomonadales	135614|Xanthomonadales	S	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
CH3_k127_9579882_4	1396418.BATQ01000106_gene5309	6.421e-120	394.0	COG1131@1|root,COG1131@2|Bacteria,46UCI@74201|Verrucomicrobia,2IU5T@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
CH3_k127_9579882_22	314256.OG2516_10581	4.585e-05	53.0	COG3637@1|root,COG3637@2|Bacteria,1RBBG@1224|Proteobacteria,2U5ED@28211|Alphaproteobacteria,2PE89@252301|Oceanicola	28211|Alphaproteobacteria	M	Outer membrane protein beta-barrel domain	lpxQ	-	-	ko:K12980	-	-	-	-	ko00000,ko01005	-	-	-	OMP_b-brl
CH3_k127_9579882_2	1396141.BATP01000009_gene2657	1.224e-128	415.0	COG2022@1|root,COG2022@2|Bacteria,46SHY@74201|Verrucomicrobia,2ITYP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Thiazole biosynthesis protein ThiG	-	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
CH3_k127_9579882_8	1396418.BATQ01000015_gene4297	2.59e-81	282.0	COG2870@1|root,COG2870@2|Bacteria,46T1J@74201|Verrucomicrobia,2IVXQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	pfkB family carbohydrate kinase	-	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	PfkB
CH3_k127_9579882_10	497964.CfE428DRAFT_0875	9.736e-78	267.0	COG0413@1|root,COG0413@2|Bacteria,46SPN@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
CH3_k127_9579882_14	497964.CfE428DRAFT_2363	9.313e-49	177.0	2DN6W@1|root,32UIF@2|Bacteria,46WNT@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_9579882_15	1128421.JAGA01000004_gene2494	3.136e-47	174.0	COG0315@1|root,COG0315@2|Bacteria,2NPNE@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	GO:0002682,GO:0002683,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016043,GO:0016829,GO:0016849,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0022607,GO:0031347,GO:0031348,GO:0034214,GO:0035821,GO:0040007,GO:0042802,GO:0043170,GO:0043207,GO:0043545,GO:0043933,GO:0044003,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0045088,GO:0045824,GO:0046483,GO:0048519,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051259,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0061799,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0075136,GO:0080134,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
CH3_k127_9579882_12	240016.ABIZ01000001_gene2198	1.359e-62	218.0	COG0521@1|root,COG0521@2|Bacteria,46SVJ@74201|Verrucomicrobia,2IUE2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Probable molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
CH3_k127_9579882_13	1396141.BATP01000057_gene2939	2.213e-53	203.0	COG0156@1|root,COG0156@2|Bacteria	2|Bacteria	E	8-amino-7-oxononanoate synthase activity	cqsA	GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769	2.3.1.29,2.3.1.47	ko:K00639,ko:K00652,ko:K10915	ko00260,ko00780,ko01100,ko02024,ko05111,map00260,map00780,map01100,map02024,map05111	M00123,M00573,M00577	R00371,R03210,R10124	RC00004,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	AMP-binding,AMP-binding_C,Aminotran_1_2,PP-binding
CH3_k127_9579882_6	1125863.JAFN01000001_gene1123	2.234e-85	295.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,42MUG@68525|delta/epsilon subdivisions,2WISB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
CH3_k127_9579882_9	1191523.MROS_2048	5.819e-81	297.0	COG0737@1|root,COG3303@1|root,COG0737@2|Bacteria,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	5_nucleotid_C,Cytochrom_C552,Cytochrome_C554,Paired_CXXCH_1,SBP_bac_8,SLH
CH3_k127_9579882_20	1396418.BATQ01000185_gene2133	4.271e-07	63.0	COG3203@1|root,COG3420@1|root,COG4782@1|root,COG5184@1|root,COG3203@2|Bacteria,COG3420@2|Bacteria,COG4782@2|Bacteria,COG5184@2|Bacteria,46TZK@74201|Verrucomicrobia	74201|Verrucomicrobia	P	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_5,Pectinesterase
CH3_k127_9613455_3	1047013.AQSP01000122_gene2224	9.092e-11	77.0	COG3291@1|root,COG5434@1|root,COG3291@2|Bacteria,COG5434@2|Bacteria,2NQ6Y@2323|unclassified Bacteria	2|Bacteria	M	PKD domain	-	-	3.2.1.157,3.2.1.91	ko:K19668,ko:K20850	ko00500,ko01100,ko02020,map00500,map01100,map02020	-	R02886,R11308	RC00799	ko00000,ko00001,ko01000	-	GH6,GH82	-	Beta_helix,CHU_C,Cadherin-like,FlgD_ig,PKD,Pectate_lyase_3
CH3_k127_9613455_5	1160721.RBI_I01576	4.706e-10	71.0	COG5283@1|root,COG5412@1|root,COG5283@2|Bacteria,COG5412@2|Bacteria,1TPR1@1239|Firmicutes,25EEJ@186801|Clostridia,3WGX8@541000|Ruminococcaceae	186801|Clostridia	S	tail tape measure protein, TP901	-	-	-	-	-	-	-	-	-	-	-	-	PhageMin_Tail
CH3_k127_9613455_7	290397.Adeh_4160	2.173e-05	54.0	COG1793@1|root,COG1793@2|Bacteria,1MV3S@1224|Proteobacteria,430DD@68525|delta/epsilon subdivisions,2WVKB@28221|Deltaproteobacteria,2YUBR@29|Myxococcales	28221|Deltaproteobacteria	F	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair	ligB	-	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
CH3_k127_9613455_1	1123288.SOV_1c01710	2.145e-48	191.0	COG0457@1|root,COG0457@2|Bacteria,1UKPT@1239|Firmicutes,4H6KP@909932|Negativicutes	909932|Negativicutes	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9,TPR_1,TPR_11,TPR_2,TPR_8
CH3_k127_9613455_6	1046714.AMRX01000006_gene2764	3.435e-06	58.0	2E7JG@1|root,3321N@2|Bacteria,1NADC@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_9613455_4	1125973.JNLC01000011_gene245	2.557e-10	69.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CH3_k127_9613455_2	760192.Halhy_0673	4.154e-13	76.0	COG4122@1|root,COG4122@2|Bacteria	2|Bacteria	E	O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_24
CH3_k127_9613455_0	398767.Glov_3367	3.742e-55	208.0	COG0438@1|root,COG0438@2|Bacteria,1RIDV@1224|Proteobacteria	1224|Proteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
CH3_k127_9618971_4	1166018.FAES_pFAES01098	6.206e-98	334.0	COG2132@1|root,COG2132@2|Bacteria,4NE3N@976|Bacteroidetes,47KSB@768503|Cytophagia	976|Bacteroidetes	Q	PFAM multicopper oxidase type 3	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
CH3_k127_9618971_1	1121447.JONL01000009_gene2551	1.145e-157	521.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,42MMV@68525|delta/epsilon subdivisions,2WIZ4@28221|Deltaproteobacteria,2M8H9@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	-	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SecA_DEAD,SecA_PP_bind
CH3_k127_9618971_0	340177.Cag_1407	5.915e-209	672.0	COG0845@1|root,COG1994@1|root,COG0845@2|Bacteria,COG1994@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	ko:K01993,ko:K13408,ko:K16922	ko04626,map04626	M00339	-	-	ko00000,ko00001,ko00002,ko01002,ko02000,ko02044	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
CH3_k127_9618971_2	340177.Cag_1408	3.213e-127	430.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02004,ko:K07798	ko02020,map02020	M00258	-	-	ko00000,ko00001,ko00002,ko02000	2.A.6.1.4,3.A.1,8.A.1	-	-	FtsX,HlyD_3,HlyD_D23,MacB_PCD
CH3_k127_9618971_12	118005.AWNK01000004_gene1113	3.985e-19	96.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
CH3_k127_9618971_8	340177.Cag_0615	1.075e-62	241.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	tolC	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
CH3_k127_9618971_5	378806.STAUR_2903	1.135e-85	323.0	COG3291@1|root,COG4257@1|root,COG3291@2|Bacteria,COG4257@2|Bacteria,1R7A1@1224|Proteobacteria,42Y4U@68525|delta/epsilon subdivisions,2WU72@28221|Deltaproteobacteria,2YZXW@29|Myxococcales	28221|Deltaproteobacteria	U	IgGFc binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_1,IgGFc_binding
CH3_k127_9618971_6	96561.Dole_1791	9.641e-83	313.0	COG1044@1|root,COG1361@1|root,COG1653@1|root,COG1044@2|Bacteria,COG1361@2|Bacteria,COG1653@2|Bacteria,1N4S6@1224|Proteobacteria,43BRE@68525|delta/epsilon subdivisions,2X729@28221|Deltaproteobacteria,2MNRP@213118|Desulfobacterales	1224|Proteobacteria	G	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_9618971_11	266779.Meso_2414	7.787e-24	120.0	COG1361@1|root,COG1361@2|Bacteria,1R5G4@1224|Proteobacteria,2UC86@28211|Alphaproteobacteria,43MTR@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	M	TIGRFAM conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
CH3_k127_9618971_10	1190603.AJYD01000022_gene371	1.825e-26	128.0	COG3391@1|root,COG3391@2|Bacteria,1MX9P@1224|Proteobacteria,1RQU8@1236|Gammaproteobacteria,1XTSY@135623|Vibrionales	135623|Vibrionales	S	Domain of unknown function (DUF4842)	VPA1172	-	-	-	-	-	-	-	-	-	-	-	DUF4842
CH3_k127_9618971_7	1173263.Syn7502_00897	2.405e-79	306.0	COG2931@1|root,COG3210@1|root,COG3386@1|root,COG5276@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3386@2|Bacteria,COG5276@2|Bacteria,1G1I0@1117|Cyanobacteria,1H1YG@1129|Synechococcus	1117|Cyanobacteria	Q	Q COG2931 RTX toxins and related Ca2 -binding proteins	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	FG-GAP,HemolysinCabind,P_proprotein,Peptidase_S8
CH3_k127_9618971_9	929556.Solca_2367	3.137e-42	183.0	COG2373@1|root,COG2373@2|Bacteria	2|Bacteria	U	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Calx-beta,DUF11,HYR,HemolysinCabind,IgGFc_binding
CH3_k127_9618971_13	929703.KE386491_gene2364	2.621e-06	64.0	COG2373@1|root,COG3209@1|root,COG3291@1|root,COG4386@1|root,COG4932@1|root,COG2373@2|Bacteria,COG3209@2|Bacteria,COG3291@2|Bacteria,COG4386@2|Bacteria,COG4932@2|Bacteria,4NJRF@976|Bacteroidetes,47PMY@768503|Cytophagia	976|Bacteroidetes	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD
CH3_k127_9618971_3	864702.OsccyDRAFT_2745	9.884e-109	404.0	COG2931@1|root,COG2931@2|Bacteria,1GHDS@1117|Cyanobacteria	1117|Cyanobacteria	Q	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,VCBS
CH3_k127_9641564_4	1265503.KB905160_gene2883	3.76e-27	122.0	2BC7U@1|root,325SP@2|Bacteria,1QMVW@1224|Proteobacteria,1TK6J@1236|Gammaproteobacteria,2Q7XB@267889|Colwelliaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_9641564_1	794903.OPIT5_28885	4.248e-113	380.0	COG0489@1|root,COG0489@2|Bacteria,46SAV@74201|Verrucomicrobia,3K75Q@414999|Opitutae	414999|Opitutae	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
CH3_k127_9641564_3	324057.Pjdr2_0886	5.183e-50	194.0	COG1470@1|root,COG3210@1|root,COG4447@1|root,COG4932@1|root,COG5492@1|root,COG1470@2|Bacteria,COG3210@2|Bacteria,COG4447@2|Bacteria,COG4932@2|Bacteria,COG5492@2|Bacteria,1TR9M@1239|Firmicutes,4HEPP@91061|Bacilli,26T62@186822|Paenibacillaceae	91061|Bacilli	U	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CBM_X2,CHB_HEX_C_1,Cadherin-like,Flg_new,SLH,fn3
CH3_k127_9641564_0	497964.CfE428DRAFT_6713	9.54e-235	737.0	COG3961@1|root,COG3961@2|Bacteria,46UYW@74201|Verrucomicrobia	74201|Verrucomicrobia	GH	Thiamine pyrophosphate enzyme, central domain	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CH3_k127_9641564_2	497964.CfE428DRAFT_5447	2.848e-112	374.0	COG0758@1|root,COG0758@2|Bacteria,46SGR@74201|Verrucomicrobia	74201|Verrucomicrobia	L	TIGRFAM DNA protecting protein DprA	smf	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A,HHH_5
CH3_k127_9650132_0	886293.Sinac_4596	1.059e-153	502.0	2DBS0@1|root,2ZANT@2|Bacteria,2IY4P@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_9650132_2	1301098.PKB_2306	9.006e-19	88.0	29MQ2@1|root,308MT@2|Bacteria,1REUR@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_9650132_1	1366050.N234_35010	3.238e-29	119.0	29MQ2@1|root,308MT@2|Bacteria,1REUR@1224|Proteobacteria,2VXQA@28216|Betaproteobacteria,1K3YT@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_9659465_0	697284.ERIC2_c41250	3.58e-125	417.0	COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,4HA06@91061|Bacilli,26RSI@186822|Paenibacillaceae	91061|Bacilli	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
CH3_k127_9659465_3	240016.ABIZ01000001_gene4459	7.525e-79	273.0	COG2103@1|root,COG2971@1|root,COG2103@2|Bacteria,COG2971@2|Bacteria,46SJI@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,SIS_2
CH3_k127_9659465_7	481448.Minf_0311	0.0001275	48.0	COG2919@1|root,COG2919@2|Bacteria,46ZEA@74201|Verrucomicrobia,37GXB@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	D	Septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
CH3_k127_9659465_4	382464.ABSI01000011_gene2535	2.471e-53	194.0	COG0233@1|root,COG0233@2|Bacteria,46V49@74201|Verrucomicrobia,2IUA0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
CH3_k127_9659465_2	1142394.PSMK_12900	1.963e-86	310.0	COG2103@1|root,COG2103@2|Bacteria	2|Bacteria	G	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	-	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	-
CH3_k127_9659465_6	247490.KSU1_D0453	6.142e-05	47.0	2EGSE@1|root,33AII@2|Bacteria,2J3TB@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_9659465_5	329726.AM1_2164	1.579e-16	82.0	COG1100@1|root,COG2319@1|root,COG4916@1|root,COG1100@2|Bacteria,COG2319@2|Bacteria,COG4916@2|Bacteria,1FZVW@1117|Cyanobacteria	1117|Cyanobacteria	A	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	WD40
CH3_k127_9659465_1	1123355.JHYO01000023_gene2360	9.914e-91	304.0	COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,2TUDG@28211|Alphaproteobacteria,36Z6S@31993|Methylocystaceae	28211|Alphaproteobacteria	E	Aminotransferase class-III	-	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CH3_k127_9659908_3	204669.Acid345_3016	1.371e-33	132.0	COG0531@1|root,COG0531@2|Bacteria,3Y3GY@57723|Acidobacteria,2JHIT@204432|Acidobacteriia	204432|Acidobacteriia	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease
CH3_k127_9659908_1	880072.Desac_2413	1.345e-111	374.0	COG1085@1|root,COG1085@2|Bacteria,1MU3E@1224|Proteobacteria,42MP4@68525|delta/epsilon subdivisions,2WKT8@28221|Deltaproteobacteria,2MR4U@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Domain of unknown function (DUF4921)	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4921,GalP_UDP_tr_C,GalP_UDP_transf
CH3_k127_9659908_0	240016.ABIZ01000001_gene1742	5.609e-113	377.0	COG1861@1|root,COG1861@2|Bacteria,46UVT@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Transposase DDE domain group 1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
CH3_k127_9659908_2	1125701.HMPREF1221_01616	1.028e-47	190.0	COG2407@1|root,COG2407@2|Bacteria	2|Bacteria	G	Converts the aldose L-fucose into the corresponding ketose L-fuculose	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_9659908_4	1125863.JAFN01000001_gene3266	5.675e-20	101.0	COG0655@1|root,COG0655@2|Bacteria,1QV9P@1224|Proteobacteria,42RJT@68525|delta/epsilon subdivisions,2WNM5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Flavodoxin domain	-	-	1.6.5.2	ko:K03809	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	FMN_red
CH3_k127_9704256_5	156889.Mmc1_2862	2.873e-37	161.0	COG0517@1|root,COG0517@2|Bacteria,1MXI6@1224|Proteobacteria,2TS6X@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
CH3_k127_9704256_1	583355.Caka_0705	7.194e-173	569.0	COG0673@1|root,COG0673@2|Bacteria,46U95@74201|Verrucomicrobia,3K969@414999|Opitutae	414999|Opitutae	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CH3_k127_9704256_4	579405.Dd703_0239	1.218e-77	269.0	COG2962@1|root,COG2962@2|Bacteria,1MX5G@1224|Proteobacteria,1RMAC@1236|Gammaproteobacteria,2JCM1@204037|Dickeya	1236|Gammaproteobacteria	S	TIGRFAM RarD protein, DMT superfamily transporter	rarD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016021,GO:0031224,GO:0044425,GO:0044464,GO:0071944	-	ko:K05786	-	-	-	-	ko00000,ko02000	2.A.7.7	-	-	EamA
CH3_k127_9704256_2	1123070.KB899255_gene1382	6.518e-125	421.0	COG0608@1|root,COG0608@2|Bacteria,46SNV@74201|Verrucomicrobia,2ITRD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	DHHA1 domain	-	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
CH3_k127_9704256_3	1521187.JPIM01000037_gene3876	1.641e-98	332.0	COG0861@1|root,COG0861@2|Bacteria,2G66P@200795|Chloroflexi,376HN@32061|Chloroflexia	32061|Chloroflexia	P	PFAM Integral membrane protein TerC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
CH3_k127_9704256_0	452637.Oter_3464	5.052e-174	575.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,46SA4@74201|Verrucomicrobia,3K770@414999|Opitutae	414999|Opitutae	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4	-	-	SecD_SecF,Sec_GG
CH3_k127_9721958_0	521674.Plim_2786	2.757e-57	207.0	COG4185@1|root,COG4185@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33,Zeta_toxin
CH3_k127_9721958_4	240016.ABIZ01000001_gene428	3.701e-12	69.0	COG1403@1|root,COG1403@2|Bacteria,46UDR@74201|Verrucomicrobia,2IUK8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH_4
CH3_k127_9721958_1	240016.ABIZ01000001_gene4597	3.134e-44	167.0	COG1403@1|root,COG1403@2|Bacteria,46UDR@74201|Verrucomicrobia,2IUK8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH_4
CH3_k127_9723000_1	945550.VISI1226_09879	2.171e-49	186.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,1RYBJ@1236|Gammaproteobacteria,1XZ3M@135623|Vibrionales	135623|Vibrionales	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CH3_k127_9723000_2	42256.RradSPS_2705	6.681e-43	180.0	COG0438@1|root,COG0438@2|Bacteria,2GM6D@201174|Actinobacteria,4CS1M@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CH3_k127_9723000_0	118168.MC7420_7993	1.091e-78	290.0	COG0510@1|root,COG0510@2|Bacteria,1G023@1117|Cyanobacteria,1HEZ0@1150|Oscillatoriales	1117|Cyanobacteria	M	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
CH3_k127_9723000_5	1396418.BATQ01000168_gene1784	1.335e-05	59.0	COG3210@1|root,COG4625@1|root,COG3210@2|Bacteria,COG4625@2|Bacteria,46UNM@74201|Verrucomicrobia,2IVJ3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	Passenger-associated-transport-repeat	-	-	-	-	-	-	-	-	-	-	-	-	PATR
CH3_k127_9723000_3	1142394.PSMK_09490	2.214e-16	93.0	COG2165@1|root,COG2165@2|Bacteria,2IXM1@203682|Planctomycetes	203682|Planctomycetes	NU	Protein of unknown function (DUF1559)	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CH3_k127_9723000_4	309807.SRU_1452	1.648e-15	90.0	2DRV2@1|root,33D77@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_9724622_2	671143.DAMO_1688	7.914e-34	139.0	COG3278@1|root,COG3278@2|Bacteria,2NRHY@2323|unclassified Bacteria	2|Bacteria	O	Belongs to the heme-copper respiratory oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_9724622_3	1051632.TPY_0746	1.347e-30	126.0	COG2151@1|root,COG2151@2|Bacteria,1V9YV@1239|Firmicutes,24VD9@186801|Clostridia	186801|Clostridia	S	Pfam:DUF59	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
CH3_k127_9724622_4	278957.ABEA03000176_gene2840	5.885e-25	107.0	COG4309@1|root,COG4309@2|Bacteria,46XTU@74201|Verrucomicrobia,3K814@414999|Opitutae	414999|Opitutae	S	Uncharacterized conserved protein (DUF2249)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2249
CH3_k127_9724622_1	392500.Swoo_0456	9.391e-44	173.0	COG4783@1|root,COG4783@2|Bacteria,1QV70@1224|Proteobacteria,1RQJV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
CH3_k127_9724622_5	382464.ABSI01000013_gene1773	4.782e-11	76.0	COG4726@1|root,COG4726@2|Bacteria,46T3V@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	Pilus assembly protein PilX	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_9724622_6	497964.CfE428DRAFT_3795	1.014e-09	72.0	COG4726@1|root,COG4726@2|Bacteria,46T3V@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	Pilus assembly protein PilX	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_9724622_0	404589.Anae109_3548	1.423e-86	317.0	COG1404@1|root,COG1572@1|root,COG1404@2|Bacteria,COG1572@2|Bacteria,1REF1@1224|Proteobacteria,42RS0@68525|delta/epsilon subdivisions,2WNDK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Peptidase_S8
CH3_k127_9729309_2	1191523.MROS_2770	1.134e-32	135.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	usp-3	-	-	-	-	-	-	-	-	-	-	-	Usp
CH3_k127_9729309_0	497964.CfE428DRAFT_6083	2.836e-286	894.0	COG1274@1|root,COG1274@2|Bacteria,46UB8@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
CH3_k127_9729309_1	756067.MicvaDRAFT_2865	5.149e-115	382.0	COG2234@1|root,COG2234@2|Bacteria,1G1QW@1117|Cyanobacteria,1H7N7@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
CH3_k127_9729309_3	1408418.JNJH01000059_gene365	0.0002558	53.0	COG3577@1|root,COG3577@2|Bacteria	2|Bacteria	S	aspartic-type endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,TPR_16,gag-asp_proteas
CH3_k127_9891171_11	349741.Amuc_0983	6.747e-10	63.0	COG3209@1|root,COG3209@2|Bacteria,46TI5@74201|Verrucomicrobia,2IVP8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	PFAM YD repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclea_NS_2,RHS_repeat
CH3_k127_9891171_7	497964.CfE428DRAFT_6409	1.499e-37	157.0	COG3209@1|root,COG3209@2|Bacteria,46TI5@74201|Verrucomicrobia	74201|Verrucomicrobia	M	PFAM YD repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
CH3_k127_9891171_3	1396418.BATQ01000133_gene3999	5.374e-120	399.0	COG0624@1|root,COG0624@2|Bacteria,46VZE@74201|Verrucomicrobia,2IW3Z@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
CH3_k127_9891171_5	748449.Halha_1319	1.536e-56	209.0	COG3940@1|root,COG3940@2|Bacteria,1UJSY@1239|Firmicutes,25F9C@186801|Clostridia,3WB0P@53433|Halanaerobiales	186801|Clostridia	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
CH3_k127_9891171_8	1123508.JH636439_gene1132	2.715e-35	153.0	COG1520@1|root,COG2373@1|root,COG2931@1|root,COG3386@1|root,COG4932@1|root,COG1520@2|Bacteria,COG2373@2|Bacteria,COG2931@2|Bacteria,COG3386@2|Bacteria,COG4932@2|Bacteria,2J4W7@203682|Planctomycetes	2|Bacteria	G	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHRD,CHU_C,DUF11,DUF4347,SdrD_B
CH3_k127_9891171_0	497964.CfE428DRAFT_1614	7.627e-295	947.0	COG1197@1|root,COG1197@2|Bacteria,46S6Y@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
CH3_k127_9891171_14	430498.S8BTV9	0.0004607	52.0	28PJD@1|root,2QW7I@2759|Eukaryota,39TJA@33154|Opisthokonta,3NWYV@4751|Fungi,3QM7J@4890|Ascomycota	4751|Fungi	G	Pectinolytic enzyme consist of four classes of enzymes pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins. Favors pectate, the anion, over pectin, the methyl ester (By similarity)	plyC	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_9891171_12	1120963.KB894499_gene421	3.378e-08	68.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.4.21.96	ko:K01361,ko:K13277,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Amidase_2,Big_2,CBM_X2,DUF1983,DUF2961,Glucosaminidase,LRR_5,Laminin_G_3,PA,Peptidase_S8,Phage-tail_3,SLH,fn3_5
CH3_k127_9891171_13	382464.ABSI01000010_gene3259	8.053e-08	63.0	COG4675@1|root,COG4675@2|Bacteria	2|Bacteria	M	tail collar domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Collar,DUF859
CH3_k127_9891171_2	530564.Psta_2735	4.695e-140	458.0	COG1520@1|root,COG1520@2|Bacteria,2IYI8@203682|Planctomycetes	203682|Planctomycetes	S	COG1520 FOG WD40-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CH3_k127_9891171_4	240016.ABIZ01000001_gene1539	9.821e-84	291.0	COG1520@1|root,COG1520@2|Bacteria,46TV4@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CH3_k127_9891171_1	886293.Sinac_6373	9.263e-198	634.0	COG0449@1|root,COG0449@2|Bacteria,2IXF9@203682|Planctomycetes	203682|Planctomycetes	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
CH3_k127_9891171_6	1121447.JONL01000003_gene3115	1.874e-39	158.0	COG0241@1|root,COG0241@2|Bacteria,1RDGR@1224|Proteobacteria,42SCB@68525|delta/epsilon subdivisions,2WPEA@28221|Deltaproteobacteria,2MBDI@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	hydrolase, HAD-superfamily, subfamily IIIA	gmhB	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like
CH3_k127_9891171_10	886293.Sinac_6222	8.787e-14	81.0	COG2165@1|root,COG2165@2|Bacteria,2J4VP@203682|Planctomycetes	203682|Planctomycetes	NU	Protein of unknown function (DUF1559)	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CH3_k127_9891171_9	378806.STAUR_1759	1.777e-19	104.0	COG3250@1|root,COG3250@2|Bacteria,1QZHW@1224|Proteobacteria	1224|Proteobacteria	G	Domain of unknown function (DUF4982)	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	DUF4982,F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_64,I-set,Ig_3
CH3_k127_9904252_0	452637.Oter_4534	0.0	1198.0	COG0458@1|root,COG0458@2|Bacteria,46UZV@74201|Verrucomicrobia,3K7MQ@414999|Opitutae	414999|Opitutae	F	Carbamoyl-phosphate synthetase large chain, oligomerisation domain	-	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
CH3_k127_9904252_1	452637.Oter_3887	2.323e-295	920.0	COG0644@1|root,COG1145@1|root,COG0644@2|Bacteria,COG1145@2|Bacteria,46WP0@74201|Verrucomicrobia	74201|Verrucomicrobia	C	oxidoreductase	-	-	1.5.5.1	ko:K00311,ko:K00313	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_3
CH3_k127_9904252_4	794903.OPIT5_30320	5.488e-17	84.0	COG4680@1|root,COG4680@2|Bacteria	2|Bacteria	K	protein conserved in bacteria	higB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009894,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0017148,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031329,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0043170,GO:0043487,GO:0043488,GO:0044237,GO:0044238,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0061013,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1903311,GO:2000112,GO:2000113	-	ko:K19166	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HigB_toxin
CH3_k127_9904252_2	794903.OPIT5_30315	1.445e-21	101.0	COG5499@1|root,COG5499@2|Bacteria	2|Bacteria	K	transcription regulator containing HTH domain	-	-	-	ko:K18831	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	HTH_3
CH3_k127_9904252_3	452637.Oter_3887	8.443e-18	84.0	COG0644@1|root,COG1145@1|root,COG0644@2|Bacteria,COG1145@2|Bacteria,46WP0@74201|Verrucomicrobia	74201|Verrucomicrobia	C	oxidoreductase	-	-	1.5.5.1	ko:K00311,ko:K00313	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_3
CH3_k127_9904252_5	357808.RoseRS_1546	2.443e-11	77.0	COG4447@1|root,COG4447@2|Bacteria,2G66V@200795|Chloroflexi,3767C@32061|Chloroflexia	32061|Chloroflexia	G	glycosyl hydrolase, BNR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_9972350_6	80637.XP_007775331.1	1.158e-98	336.0	KOG0272@1|root,KOG0272@2759|Eukaryota	2759|Eukaryota	S	U4 snRNA binding	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,NACHT,WD40
CH3_k127_9972350_4	1158292.JPOE01000005_gene813	8.695e-129	421.0	COG3335@1|root,COG3335@2|Bacteria,1MW7X@1224|Proteobacteria,2VMDX@28216|Betaproteobacteria	28216|Betaproteobacteria	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_23
CH3_k127_9972350_8	794903.OPIT5_16540	2.657e-81	290.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,Nterm_IS4
CH3_k127_9972350_31	1229780.BN381_750002	0.000139	52.0	2C62F@1|root,335K1@2|Bacteria,2GS5K@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_9972350_2	1131269.AQVV01000050_gene418	2.35e-130	425.0	COG2107@1|root,COG2107@2|Bacteria	2|Bacteria	S	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K07083,ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
CH3_k127_9972350_18	886293.Sinac_6513	6.66e-19	102.0	291K2@1|root,2ZP6D@2|Bacteria,2IZ9X@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3352
CH3_k127_9972350_9	1123242.JH636435_gene1022	3.603e-75	271.0	COG0265@1|root,COG0265@2|Bacteria,2IYNW@203682|Planctomycetes	203682|Planctomycetes	O	C-terminal PDZ domain	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	Trypsin_2
CH3_k127_9972350_25	1286632.P278_17170	1.988e-13	78.0	COG0746@1|root,COG0746@2|Bacteria,4NSH9@976|Bacteroidetes,1I46A@117743|Flavobacteriia	976|Bacteroidetes	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
CH3_k127_9972350_5	497964.CfE428DRAFT_3889	1.266e-128	428.0	COG0332@1|root,COG0332@2|Bacteria,46SE2@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
CH3_k127_9972350_7	497964.CfE428DRAFT_3890	1.072e-83	290.0	COG0416@1|root,COG0416@2|Bacteria,46S8C@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
CH3_k127_9972350_23	316067.Geob_2610	6.255e-14	74.0	COG0333@1|root,COG0333@2|Bacteria,1NGM1@1224|Proteobacteria,42XHF@68525|delta/epsilon subdivisions,2WSX6@28221|Deltaproteobacteria,43SSW@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	structural constituent of ribosome	rpmF	GO:0003674,GO:0003735,GO:0005198	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
CH3_k127_9972350_24	313628.LNTAR_24436	1.353e-13	78.0	COG1399@1|root,COG1399@2|Bacteria	2|Bacteria	K	metal-binding, possibly nucleic acid-binding protein	yceD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
CH3_k127_9972350_11	497964.CfE428DRAFT_3893	4.53e-56	201.0	COG0669@1|root,COG0669@2|Bacteria,46SUT@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
CH3_k127_9972350_12	404380.Gbem_0296	3.62e-46	190.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,42N5S@68525|delta/epsilon subdivisions,2WIUS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
CH3_k127_9972350_28	889378.Spiaf_1773	6.601e-08	63.0	COG2885@1|root,COG4254@1|root,COG2885@2|Bacteria,COG4254@2|Bacteria	2|Bacteria	UW	PFAM FecR protein	-	-	1.9.3.1	ko:K02275,ko:K03286	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.6,3.D.4.2,3.D.4.4,3.D.4.6	-	-	Big_2,COX2,COX2_TM,FecR,OmpA,TPR_16,fn3
CH3_k127_9972350_13	497964.CfE428DRAFT_2202	6.992e-44	181.0	COG3307@1|root,COG3307@2|Bacteria,46TC1@74201|Verrucomicrobia	74201|Verrucomicrobia	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
CH3_k127_9972350_26	1191523.MROS_1643	2.13e-12	69.0	2EGPU@1|root,33AFZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_9972350_19	439235.Dalk_4189	8.608e-17	92.0	COG2755@1|root,COG2755@2|Bacteria,1NHW6@1224|Proteobacteria,42XAM@68525|delta/epsilon subdivisions,2WSXZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CH3_k127_9972350_17	314345.SPV1_00507	3.429e-21	98.0	COG2192@1|root,COG2192@2|Bacteria,1R3MX@1224|Proteobacteria	1224|Proteobacteria	O	nodulation	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_9972350_0	1499967.BAYZ01000095_gene4126	1.694e-294	913.0	COG2192@1|root,COG2192@2|Bacteria,2NNRR@2323|unclassified Bacteria	2|Bacteria	O	Carbamoyltransferase C-terminus	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
CH3_k127_9972350_15	1403819.BATR01000005_gene177	2.295e-32	145.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,46TYP@74201|Verrucomicrobia,2IVFI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CG	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,VCBS
CH3_k127_9972350_1	223192.XP_007915956.1	3.298e-136	458.0	COG4030@1|root,2SKR2@2759|Eukaryota,39W5K@33154|Opisthokonta,3NXCY@4751|Fungi,3QPYP@4890|Ascomycota,21CB8@147550|Sordariomycetes	4751|Fungi	S	Protein of unknown function (DUF2961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
CH3_k127_9972350_27	111781.Lepto7376_3756	6.151e-12	79.0	COG1572@1|root,COG3209@1|root,COG3210@1|root,COG1572@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	3.2.1.78	ko:K01218	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000	-	GH26	-	CARDB,RHS_repeat
CH3_k127_9972350_16	1403819.BATR01000008_gene271	5.451e-25	111.0	COG0458@1|root,COG0458@2|Bacteria,46SBT@74201|Verrucomicrobia,2IU2N@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EF	Carbamoyl-phosphate synthetase large chain, oligomerisation domain	-	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
CH3_k127_9972350_3	1496688.ER33_13835	1.204e-129	416.0	COG0426@1|root,COG0426@2|Bacteria,1GPET@1117|Cyanobacteria,22SW2@167375|Cyanobium	1117|Cyanobacteria	C	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_9972350_30	1288963.ADIS_0520	2.474e-05	54.0	COG2350@1|root,COG2350@2|Bacteria,4NRC1@976|Bacteroidetes,47X4I@768503|Cytophagia	976|Bacteroidetes	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
CH3_k127_9972350_20	497964.CfE428DRAFT_0072	4.161e-16	81.0	COG0458@1|root,COG0458@2|Bacteria,46SBT@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Carbamoyl-phosphate synthetase ammonia chain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
CH3_k127_9972350_22	1123277.KB893244_gene5105	1.756e-14	83.0	COG4733@1|root,COG4733@2|Bacteria,4NK2V@976|Bacteroidetes,47P6C@768503|Cytophagia	976|Bacteroidetes	G	PFAM Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
CH3_k127_9972350_29	886293.Sinac_7118	1.84e-05	51.0	COG3119@1|root,COG3119@2|Bacteria,2IXIE@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	DUF4994,Sulfatase
CH3_k127_9972350_10	1341155.FSS13T_20250	6.278e-57	224.0	COG1073@1|root,COG1073@2|Bacteria,4NFRN@976|Bacteroidetes,1HWSK@117743|Flavobacteriia,2NUEG@237|Flavobacterium	976|Bacteroidetes	S	BAAT / Acyl-CoA thioester hydrolase C terminal	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	BAAT_C,Hydrolase_4
CH3_k127_9972350_21	1185876.BN8_01058	8.837e-15	87.0	COG4733@1|root,COG4733@2|Bacteria,4NK2V@976|Bacteroidetes,47P6C@768503|Cytophagia	976|Bacteroidetes	G	PFAM Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
CH3_k127_9972350_14	402777.KB235903_gene2405	1.084e-43	175.0	COG1361@1|root,COG2373@1|root,COG2931@1|root,COG4222@1|root,COG1361@2|Bacteria,COG2373@2|Bacteria,COG2931@2|Bacteria,COG4222@2|Bacteria,1G4X1@1117|Cyanobacteria,1HAE3@1150|Oscillatoriales	1117|Cyanobacteria	Q	PFAM Hemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4347,He_PIG,HemolysinCabind
CH3_k127_9986657_1	595460.RRSWK_06070	1.573e-93	316.0	COG0673@1|root,COG0673@2|Bacteria,2IXJ0@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CH3_k127_9986657_3	373994.Riv7116_3284	2.337e-65	235.0	COG4223@1|root,COG4223@2|Bacteria	2|Bacteria	DZ	transferase activity, transferring acyl groups other than amino-acyl groups	elrF	-	-	-	-	-	-	-	-	-	-	-	Cutinase,DUF1350,DUF1631
CH3_k127_9986657_4	240016.ABIZ01000001_gene54	1.841e-17	83.0	COG3356@1|root,COG3356@2|Bacteria,46XH2@74201|Verrucomicrobia,2IVWJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Neutral/alkaline non-lysosomal ceramidase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
CH3_k127_9986657_0	926550.CLDAP_30260	4.313e-98	356.0	COG3387@1|root,COG3387@2|Bacteria	2|Bacteria	G	glucan 1,4-alpha-glucosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N,F5_F8_type_C,Glyco_hydro_125
CH3_k127_9986657_2	1158294.JOMI01000007_gene99	8.457e-73	254.0	COG3408@1|root,COG3408@2|Bacteria,4NJY8@976|Bacteroidetes,2G2N9@200643|Bacteroidia	976|Bacteroidetes	G	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
CH3_k127_9992144_3	237368.SCABRO_00954	4.256e-11	66.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_4
CH3_k127_9992144_0	452637.Oter_2229	3.928e-273	870.0	COG2273@1|root,COG2273@2|Bacteria	2|Bacteria	G	xyloglucan:xyloglucosyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Glyco_hydro_16,Glyco_transf_25,Malectin,Ricin_B_lectin,Trans_reg_C,Trypsin,VCBS
CH3_k127_9992144_2	700598.Niako_5388	2.159e-52	198.0	COG3669@1|root,COG3669@2|Bacteria,4NWP5@976|Bacteroidetes	976|Bacteroidetes	G	Alpha-L-fucosidase	-	-	-	-	-	-	-	-	-	-	-	-	Alpha_L_fucos
CH3_k127_9992144_1	530564.Psta_0688	4.577e-160	516.0	28MMN@1|root,2ZAXE@2|Bacteria,2IY1P@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CH3_k127_999470_0	1396141.BATP01000023_gene745	1.134e-66	235.0	COG1482@1|root,COG1482@2|Bacteria,46SVM@74201|Verrucomicrobia,2IU31@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Phosphomannose isomerase type I	-	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	PMI_typeI
CH3_k127_999470_3	331678.Cphamn1_1444	2.596e-17	89.0	COG1950@1|root,COG1950@2|Bacteria,1FE4Y@1090|Chlorobi	1090|Chlorobi	S	PFAM membrane protein of	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
CH3_k127_999470_1	497964.CfE428DRAFT_0169	5.644e-40	155.0	COG0220@1|root,COG0220@2|Bacteria,46T5A@74201|Verrucomicrobia	74201|Verrucomicrobia	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	-	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
## 5450 queries scanned
## Total time (seconds): 8.279800176620483
## Rate: 658.23 q/s