## Mon Feb 16 04:44:56 2026
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/bins/CMS1_bin.107.fa -m mmseqs --output CMS1_bin.107 --output_dir /data/result/bins/wyx/eggqs50+/CMS1_bin.107 --itype genome --cpu 8 --override
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
CMS1_k127_1002917_2	702113.PP1Y_AT5612	7.35e-91	302.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2TQND@28211|Alphaproteobacteria,2K04K@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CMS1_k127_1002917_7	1335760.ASTG01000007_gene880	2.201e-69	241.0	COG0132@1|root,COG0132@2|Bacteria,1RDRK@1224|Proteobacteria,2U5AJ@28211|Alphaproteobacteria,2K151@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	-	2.1.1.197,6.3.3.3	ko:K01935,ko:K02169	ko00780,ko01100,map00780,map01100	M00123,M00572,M00573,M00577	R03182,R09543	RC00003,RC00460,RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
CMS1_k127_1002917_0	1174684.EBMC1_12806	2.933e-127	418.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,2TTAK@28211|Alphaproteobacteria,2JZVV@204457|Sphingomonadales	204457|Sphingomonadales	E	8-amino-7-oxononanoate synthase	bioF	-	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS1_k127_1002917_6	1123270.ATUR01000004_gene1499	3.511e-72	266.0	COG1407@1|root,COG1407@2|Bacteria,1RC5G@1224|Proteobacteria,2TU2T@28211|Alphaproteobacteria,2K25E@204457|Sphingomonadales	204457|Sphingomonadales	S	ICC-like phosphoesterases	-	-	-	ko:K06953	-	-	-	-	ko00000	-	-	-	Metallophos
CMS1_k127_1002917_1	1296990.H845_1198	3.773e-123	402.0	COG1054@1|root,COG1054@2|Bacteria,1MUFV@1224|Proteobacteria,2TUB5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Belongs to the UPF0176 family	yceA	-	-	ko:K07146	-	-	-	-	ko00000	-	-	-	Rhodanese
CMS1_k127_1002917_5	1280947.HY30_00010	3.556e-81	276.0	COG0625@1|root,COG0625@2|Bacteria,1RD2G@1224|Proteobacteria,2U7CB@28211|Alphaproteobacteria,43XNW@69657|Hyphomonadaceae	28211|Alphaproteobacteria	O	Glutathione S-transferase	-	-	-	-	-	-	-	-	-	-	-	-	GST_C,GST_C_2,GST_N_3
CMS1_k127_1002917_8	1088721.NSU_3293	7.952e-60	218.0	29TFP@1|root,30ENV@2|Bacteria,1RG86@1224|Proteobacteria,2UBEB@28211|Alphaproteobacteria,2K5KS@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
CMS1_k127_1002917_3	1248760.ANFZ01000006_gene2462	4.914e-85	293.0	COG3577@1|root,COG3577@2|Bacteria,1MYAD@1224|Proteobacteria,2U9RE@28211|Alphaproteobacteria,2K4GD@204457|Sphingomonadales	204457|Sphingomonadales	S	gag-polyprotein putative aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2
CMS1_k127_1002917_4	1248760.ANFZ01000006_gene2462	2.47e-82	284.0	COG3577@1|root,COG3577@2|Bacteria,1MYAD@1224|Proteobacteria,2U9RE@28211|Alphaproteobacteria,2K4GD@204457|Sphingomonadales	204457|Sphingomonadales	S	gag-polyprotein putative aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2
CMS1_k127_1002917_9	1248760.ANFZ01000006_gene2463	1.243e-28	115.0	COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,2TR7V@28211|Alphaproteobacteria,2K0I6@204457|Sphingomonadales	204457|Sphingomonadales	L	helicase	lhr	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
CMS1_k127_101223_6	1123270.ATUR01000005_gene421	4.426e-77	259.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,2TSTH@28211|Alphaproteobacteria,2K101@204457|Sphingomonadales	204457|Sphingomonadales	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
CMS1_k127_101223_0	1545915.JROG01000001_gene488	3.763e-256	814.0	COG3975@1|root,COG3975@2|Bacteria,1MUHZ@1224|Proteobacteria,2TRZF@28211|Alphaproteobacteria,2K0CU@204457|Sphingomonadales	204457|Sphingomonadales	S	protease with the C-terminal PDZ	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M61
CMS1_k127_101223_4	1123270.ATUR01000005_gene423	5.308e-107	348.0	COG0221@1|root,COG0221@2|Bacteria,1RA2F@1224|Proteobacteria,2TQZM@28211|Alphaproteobacteria,2K19Z@204457|Sphingomonadales	204457|Sphingomonadales	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
CMS1_k127_101223_5	1234595.C725_0848	3.206e-85	289.0	2DBB1@1|root,2Z854@2|Bacteria,1RJKG@1224|Proteobacteria,2U3G4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Domain of Unknown Function (DUF1206)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1206
CMS1_k127_101223_1	1030157.AFMP01000016_gene2394	6.128e-216	674.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,2TRXK@28211|Alphaproteobacteria,2K12N@204457|Sphingomonadales	204457|Sphingomonadales	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
CMS1_k127_101223_3	1123270.ATUR01000005_gene427	4.481e-129	415.0	COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,2TR4J@28211|Alphaproteobacteria,2K0GH@204457|Sphingomonadales	204457|Sphingomonadales	C	Electron transfer flavoprotein	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
CMS1_k127_101223_2	1545915.JROG01000001_gene492	7.79e-163	516.0	COG2025@1|root,COG2025@2|Bacteria,1MUFI@1224|Proteobacteria,2TR10@28211|Alphaproteobacteria,2K1AU@204457|Sphingomonadales	204457|Sphingomonadales	C	Electron transfer flavoprotein	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
CMS1_k127_101223_7	13689.BV96_02235	2.114e-60	212.0	COG0316@1|root,COG0316@2|Bacteria,1RH6T@1224|Proteobacteria,2UBWJ@28211|Alphaproteobacteria,2K4FF@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the HesB IscA family	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
CMS1_k127_101223_8	1123270.ATUR01000007_gene1297	2.742e-45	164.0	COG2151@1|root,COG2151@2|Bacteria,1MZ9Y@1224|Proteobacteria,2U72U@28211|Alphaproteobacteria,2K4IC@204457|Sphingomonadales	204457|Sphingomonadales	S	FeS assembly SUF system protein	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
CMS1_k127_1013462_4	745310.G432_15665	2.865e-12	67.0	COG4530@1|root,COG4530@2|Bacteria,1N42Z@1224|Proteobacteria,2UDI6@28211|Alphaproteobacteria,2K62H@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (FYDLN_acid)	-	-	-	-	-	-	-	-	-	-	-	-	FYDLN_acid
CMS1_k127_1013462_1	627192.SLG_16590	3.568e-186	591.0	COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,2TR6W@28211|Alphaproteobacteria,2K0WH@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
CMS1_k127_1013462_3	1537715.JQFJ01000002_gene859	6.313e-15	78.0	2EFVT@1|root,339N0@2|Bacteria,1MZTF@1224|Proteobacteria,2UIK5@28211|Alphaproteobacteria,2KE14@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1013462_2	59538.XP_005974197.1	4.576e-78	268.0	2CZG6@1|root,2SA96@2759|Eukaryota	2759|Eukaryota	S	Cytidylate kinase	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin
CMS1_k127_1013462_0	1248760.ANFZ01000004_gene1913	6.244e-320	987.0	COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,2TQPV@28211|Alphaproteobacteria,2K0KT@204457|Sphingomonadales	204457|Sphingomonadales	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
CMS1_k127_1020438_4	645512.GCWU000246_01147	7.351e-21	92.0	COG0626@1|root,COG0626@2|Bacteria,3TCJT@508458|Synergistetes	508458|Synergistetes	E	Cys Met metabolism	-	-	4.4.1.11	ko:K01761	ko00270,ko00450,map00270,map00450	-	R00654,R04770	RC00196,RC00348,RC01209,RC01210	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
CMS1_k127_1020438_0	631454.N177_1437	3.214e-153	496.0	COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,2TUFB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
CMS1_k127_1020438_1	1231391.AMZF01000026_gene197	6.958e-143	467.0	COG0775@1|root,COG0775@2|Bacteria,1MUMQ@1224|Proteobacteria,2VKRE@28216|Betaproteobacteria,3T2X5@506|Alcaligenaceae	28216|Betaproteobacteria	F	Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations	amn	-	3.2.2.4	ko:K01241	ko00230,map00230	-	R00182	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	AMNp_N,PNP_UDP_1
CMS1_k127_1020438_3	392499.Swit_2712	8.155e-60	219.0	COG5387@1|root,COG5387@2|Bacteria,1Q3B5@1224|Proteobacteria,2TVK1@28211|Alphaproteobacteria,2K1FD@204457|Sphingomonadales	204457|Sphingomonadales	O	Chaperone required for the assembly of the mitochondrial F1-ATPase	-	-	-	-	-	-	-	-	-	-	-	-	ATP12
CMS1_k127_1020438_2	1112216.JH594425_gene1660	1.227e-69	240.0	COG0546@1|root,COG0546@2|Bacteria,1RDA7@1224|Proteobacteria,2U703@28211|Alphaproteobacteria,2K3XQ@204457|Sphingomonadales	204457|Sphingomonadales	S	Hydrolase	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
CMS1_k127_102871_4	279238.Saro_1154	1.038e-43	160.0	COG3829@1|root,COG3829@2|Bacteria,1QUPP@1224|Proteobacteria,2TR58@28211|Alphaproteobacteria,2K0CK@204457|Sphingomonadales	204457|Sphingomonadales	K	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain	pspF	-	-	ko:K03974	-	-	-	-	ko00000,ko03000	-	-	-	HTH_8,Sigma54_activat
CMS1_k127_102871_0	1123270.ATUR01000002_gene2694	6.034e-91	306.0	COG1842@1|root,COG1842@2|Bacteria,1NC7S@1224|Proteobacteria,2U6CN@28211|Alphaproteobacteria,2K2DP@204457|Sphingomonadales	204457|Sphingomonadales	KT	Phage shock protein A	pspA	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
CMS1_k127_102871_7	1248760.ANFZ01000009_gene883	6.909e-32	126.0	2EH78@1|root,33AZ2@2|Bacteria,1N7AP@1224|Proteobacteria,2UGJI@28211|Alphaproteobacteria,2K6SQ@204457|Sphingomonadales	204457|Sphingomonadales	S	Phage shock protein B	pspB	-	-	ko:K03970	-	-	-	-	ko00000,ko02048	-	-	-	PspB
CMS1_k127_102871_3	317655.Sala_0209	8.761e-48	177.0	COG1983@1|root,COG1983@2|Bacteria,1NECC@1224|Proteobacteria,2UEYZ@28211|Alphaproteobacteria,2KCGA@204457|Sphingomonadales	204457|Sphingomonadales	KT	PspC domain	-	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	PspC
CMS1_k127_102871_6	1379701.JPJC01000063_gene1402	4.008e-35	136.0	28X1J@1|root,2ZJ09@2|Bacteria,1N9NE@1224|Proteobacteria,2UHAN@28211|Alphaproteobacteria,2K696@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_102871_5	1537715.JQFJ01000002_gene2297	1.96e-40	152.0	28X1J@1|root,344AU@2|Bacteria,1N404@1224|Proteobacteria,2UC94@28211|Alphaproteobacteria,2K65T@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_102871_8	627192.SLG_36120	4.299e-23	102.0	2DNTE@1|root,32Z25@2|Bacteria,1NC1W@1224|Proteobacteria,2UGD6@28211|Alphaproteobacteria,2KCC6@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_102871_11	1248760.ANFZ01000009_gene879	7.018e-06	51.0	2ADWV@1|root,313NY@2|Bacteria,1N7F8@1224|Proteobacteria,2UF5X@28211|Alphaproteobacteria,2K6VX@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_102871_10	1545915.JROG01000003_gene676	4.25e-17	83.0	2DNTE@1|root,32Z25@2|Bacteria,1NK1C@1224|Proteobacteria,2UJRY@28211|Alphaproteobacteria,2K7CU@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_102871_9	13690.CP98_02273	9.783e-20	91.0	29B0T@1|root,2ZXZQ@2|Bacteria,1ND25@1224|Proteobacteria,2UJ2J@28211|Alphaproteobacteria,2K6SU@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_102871_2	1335760.ASTG01000015_gene3286	1.918e-62	217.0	COG2166@1|root,COG2166@2|Bacteria,1RI8F@1224|Proteobacteria,2U9A2@28211|Alphaproteobacteria,2K4H9@204457|Sphingomonadales	204457|Sphingomonadales	S	SufE protein probably involved in Fe-S center assembly	sufE	-	-	ko:K02426	-	-	-	-	ko00000	-	-	-	SufE
CMS1_k127_102871_1	1502850.FG91_04019	7.295e-85	283.0	COG0484@1|root,COG0484@2|Bacteria,1RASJ@1224|Proteobacteria,2U5FR@28211|Alphaproteobacteria,2K3W9@204457|Sphingomonadales	204457|Sphingomonadales	O	molecular chaperone	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
CMS1_k127_1056220_7	237727.NAP1_02165	1.253e-63	231.0	COG1511@1|root,COG5295@1|root,COG1511@2|Bacteria,COG5295@2|Bacteria,1N338@1224|Proteobacteria,2U7KW@28211|Alphaproteobacteria,2K2HA@204457|Sphingomonadales	204457|Sphingomonadales	UW	Head domain of trimeric autotransporter adhesin	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	YadA_anchor,YadA_head
CMS1_k127_1056220_6	194867.ALBQ01000014_gene495	2.619e-67	235.0	COG2335@1|root,COG2335@2|Bacteria,1RD06@1224|Proteobacteria,2U7H5@28211|Alphaproteobacteria,2K4RQ@204457|Sphingomonadales	204457|Sphingomonadales	M	COG2335 Secreted and surface protein containing fasciclin-like repeats	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
CMS1_k127_1056220_9	1144307.PMI04_04295	3.665e-49	184.0	COG5343@1|root,COG5343@2|Bacteria,1N821@1224|Proteobacteria,2UF3V@28211|Alphaproteobacteria,2K4R7@204457|Sphingomonadales	204457|Sphingomonadales	S	Anti-sigma-K factor rskA	-	-	-	-	-	-	-	-	-	-	-	-	RskA
CMS1_k127_1056220_8	1207055.C100_09325	3.722e-55	199.0	COG1595@1|root,COG1595@2|Bacteria,1N00E@1224|Proteobacteria,2U6J3@28211|Alphaproteobacteria,2K57J@204457|Sphingomonadales	204457|Sphingomonadales	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_1056220_13	570967.JMLV01000004_gene557	0.0003874	48.0	2EHSA@1|root,33BI1@2|Bacteria,1NISY@1224|Proteobacteria,2UKJ2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1056220_1	670292.JH26_09120	7.125e-139	449.0	COG1052@1|root,COG1052@2|Bacteria,1MVSS@1224|Proteobacteria,2TV4N@28211|Alphaproteobacteria,1JSDD@119045|Methylobacteriaceae	28211|Alphaproteobacteria	CH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	ldhA	-	1.1.1.28	ko:K03778	ko00620,ko01120,map00620,map01120	-	R00704	RC00044	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
CMS1_k127_1056220_10	1549858.MC45_00175	2.063e-45	172.0	COG0454@1|root,COG0456@2|Bacteria,1MYY6@1224|Proteobacteria,2UBIF@28211|Alphaproteobacteria,2K537@204457|Sphingomonadales	204457|Sphingomonadales	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_3
CMS1_k127_1056220_2	1449076.JOOE01000001_gene2075	5.57e-104	351.0	COG0845@1|root,COG0845@2|Bacteria,1Q10W@1224|Proteobacteria,2TSC8@28211|Alphaproteobacteria,2K9U3@204457|Sphingomonadales	204457|Sphingomonadales	M	HlyD family secretion protein	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_3
CMS1_k127_1056220_0	1449076.JOOE01000001_gene2076	2.595e-232	743.0	COG0577@1|root,COG0577@2|Bacteria,1MW6D@1224|Proteobacteria,2TTJZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	COG0577 ABC-type antimicrobial peptide transport system permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS1_k127_1056220_3	1449076.JOOE01000001_gene2077	4.43e-97	323.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2VEU2@28211|Alphaproteobacteria,2K9NX@204457|Sphingomonadales	204457|Sphingomonadales	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_1056220_12	231434.JQJH01000004_gene536	4.189e-17	87.0	COG5622@1|root,COG5622@2|Bacteria,1RIEJ@1224|Proteobacteria,2U7UE@28211|Alphaproteobacteria,3NBQC@45404|Beijerinckiaceae	28211|Alphaproteobacteria	N	Protein required for attachment to host cells	MA20_35675	-	-	-	-	-	-	-	-	-	-	-	Host_attach
CMS1_k127_1056220_4	46429.BV95_02810	8.475e-82	279.0	COG1926@1|root,COG1926@2|Bacteria,1RAG8@1224|Proteobacteria,2U5HS@28211|Alphaproteobacteria,2KA2C@204457|Sphingomonadales	204457|Sphingomonadales	S	Phosphoribosyl transferase domain	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	Pribosyltran
CMS1_k127_1056220_5	702113.PP1Y_Mpl5962	2.791e-78	268.0	COG1073@1|root,COG1073@2|Bacteria,1RDAY@1224|Proteobacteria,2U5QZ@28211|Alphaproteobacteria,2KA04@204457|Sphingomonadales	204457|Sphingomonadales	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1056220_11	702113.PP1Y_Mpl5969	1.564e-20	90.0	COG2312@1|root,COG2312@2|Bacteria,1MU2S@1224|Proteobacteria,2TWB5@28211|Alphaproteobacteria,2K7QR@204457|Sphingomonadales	204457|Sphingomonadales	S	Erythromycin esterase	-	-	-	-	-	-	-	-	-	-	-	-	Erythro_esteras
CMS1_k127_1061970_1	1088721.NSU_1449	2.32e-75	255.0	COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,2TQQS@28211|Alphaproteobacteria,2K107@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
CMS1_k127_1061970_3	702113.PP1Y_AT27515	5.847e-49	181.0	COG1225@1|root,COG1225@2|Bacteria,1RHSM@1224|Proteobacteria,2U9FF@28211|Alphaproteobacteria,2K56N@204457|Sphingomonadales	204457|Sphingomonadales	O	Peroxiredoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS1_k127_1061970_0	745310.G432_11160	0.0	1134.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,2TQRR@28211|Alphaproteobacteria,2K09S@204457|Sphingomonadales	204457|Sphingomonadales	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
CMS1_k127_1061970_2	745310.G432_11165	3.143e-58	205.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,2TQJT@28211|Alphaproteobacteria,2JZY4@204457|Sphingomonadales	204457|Sphingomonadales	C	Malic enzyme	maeB	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,PTA_PTB,malic
CMS1_k127_1083475_3	1123270.ATUR01000003_gene866	3.787e-10	61.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,2TQZG@28211|Alphaproteobacteria,2K1MK@204457|Sphingomonadales	204457|Sphingomonadales	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS1_k127_1083475_1	1123269.NX02_11605	3.517e-137	442.0	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,2TRTT@28211|Alphaproteobacteria,2K15H@204457|Sphingomonadales	204457|Sphingomonadales	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
CMS1_k127_1083475_2	1248760.ANFZ01000006_gene2515	3.439e-128	424.0	COG3173@1|root,COG3173@2|Bacteria,1MY0Y@1224|Proteobacteria,2TRMW@28211|Alphaproteobacteria,2K1BV@204457|Sphingomonadales	204457|Sphingomonadales	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS1_k127_1083475_0	1044.EH31_13980	4.851e-144	463.0	COG1960@1|root,COG1960@2|Bacteria,1MWUU@1224|Proteobacteria,2TT47@28211|Alphaproteobacteria,2K2YK@204457|Sphingomonadales	204457|Sphingomonadales	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS1_k127_1089336_35	383381.EH30_02040	4.375e-09	58.0	2CF7S@1|root,32S1E@2|Bacteria,1R918@1224|Proteobacteria,2U3VN@28211|Alphaproteobacteria,2K2C5@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1089336_9	314225.ELI_10335	6.806e-148	481.0	2DBMQ@1|root,2Z9ZP@2|Bacteria,1QVZU@1224|Proteobacteria,2U5JS@28211|Alphaproteobacteria,2K406@204457|Sphingomonadales	204457|Sphingomonadales	S	Conserved TM helix	-	-	-	-	-	-	-	-	-	-	-	-	TM_helix
CMS1_k127_1089336_23	258594.RPA2184	7.495e-86	295.0	COG0604@1|root,COG0604@2|Bacteria,1MWRK@1224|Proteobacteria,2TQMF@28211|Alphaproteobacteria,3JU48@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Zinc-binding dehydrogenase	MA20_32380	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_1089336_8	1545915.JROG01000004_gene2467	4.722e-155	505.0	COG1680@1|root,COG1680@2|Bacteria,1MY4Y@1224|Proteobacteria,2TTG4@28211|Alphaproteobacteria,2K1ZW@204457|Sphingomonadales	204457|Sphingomonadales	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS1_k127_1089336_3	627192.SLG_21430	2.683e-215	676.0	COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,2TQVF@28211|Alphaproteobacteria,2K1Z2@204457|Sphingomonadales	204457|Sphingomonadales	L	ATPase related to the helicase subunit of the Holliday junction resolvase	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
CMS1_k127_1089336_5	1545915.JROG01000008_gene3358	8.03e-191	602.0	COG0438@1|root,COG0438@2|Bacteria,1MUB7@1224|Proteobacteria,2TQQ0@28211|Alphaproteobacteria,2K14F@204457|Sphingomonadales	204457|Sphingomonadales	M	Glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
CMS1_k127_1089336_24	1192759.AKIB01000023_gene2851	2.315e-79	270.0	COG2258@1|root,COG2258@2|Bacteria,1RAPM@1224|Proteobacteria,2U5IG@28211|Alphaproteobacteria,2K3XH@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	3-alpha,MOSC
CMS1_k127_1089336_14	1123270.ATUR01000005_gene511	3.792e-121	396.0	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,2TVFA@28211|Alphaproteobacteria,2K03F@204457|Sphingomonadales	204457|Sphingomonadales	S	COG1253 Hemolysins and related proteins containing CBS domains	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC
CMS1_k127_1089336_28	13690.CP98_00705	2.187e-47	178.0	COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,2UBXV@28211|Alphaproteobacteria,2K4EE@204457|Sphingomonadales	204457|Sphingomonadales	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
CMS1_k127_1089336_12	1007104.SUS17_3855	2.426e-141	457.0	COG1702@1|root,COG1702@2|Bacteria,1MVDV@1224|Proteobacteria,2TRV3@28211|Alphaproteobacteria,2K21F@204457|Sphingomonadales	204457|Sphingomonadales	T	Phosphate starvation-inducible protein PhoH	-	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
CMS1_k127_1089336_1	1114964.L485_20915	2.427e-222	695.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,2TQN6@28211|Alphaproteobacteria,2K1NH@204457|Sphingomonadales	204457|Sphingomonadales	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
CMS1_k127_1089336_17	1248760.ANFZ01000011_gene267	8.767e-109	357.0	COG0204@1|root,COG0204@2|Bacteria,1N2DG@1224|Proteobacteria,2TT8Q@28211|Alphaproteobacteria,2K221@204457|Sphingomonadales	204457|Sphingomonadales	I	Acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
CMS1_k127_1089336_25	1248760.ANFZ01000011_gene266	1.721e-76	257.0	COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,2U6ZS@28211|Alphaproteobacteria,2K3Z2@204457|Sphingomonadales	204457|Sphingomonadales	K	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
CMS1_k127_1089336_26	1123270.ATUR01000005_gene505	6.117e-61	212.0	COG4957@1|root,COG4957@2|Bacteria,1RGUW@1224|Proteobacteria,2U99M@28211|Alphaproteobacteria,2K5ZE@204457|Sphingomonadales	204457|Sphingomonadales	K	ROS/MUCR transcriptional regulator protein	-	-	-	-	-	-	-	-	-	-	-	-	ROS_MUCR
CMS1_k127_1089336_31	291985.CCSI01000005_gene926	8.063e-31	127.0	COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,2UF5C@28211|Alphaproteobacteria,2K616@204457|Sphingomonadales	204457|Sphingomonadales	K	Acetyltransferase	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
CMS1_k127_1089336_27	1545915.JROG01000008_gene3366	5.406e-56	202.0	COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,2TTM2@28211|Alphaproteobacteria,2K59A@204457|Sphingomonadales	204457|Sphingomonadales	O	peptidase M22	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M22
CMS1_k127_1089336_19	1123270.ATUR01000005_gene503	3.223e-96	317.0	COG0778@1|root,COG0778@2|Bacteria,1R9VX@1224|Proteobacteria,2U5B0@28211|Alphaproteobacteria,2K16Z@204457|Sphingomonadales	204457|Sphingomonadales	C	Nitroreductase family	-	-	-	ko:K09019	ko00240,ko01100,map00240,map01100	-	R09289	RC00087	ko00000,ko00001,ko01000	-	-	-	Nitroreductase
CMS1_k127_1089336_20	1114964.L485_20885	2.519e-93	309.0	COG0694@1|root,COG0694@2|Bacteria,1MVQ1@1224|Proteobacteria,2TUD1@28211|Alphaproteobacteria,2K0IN@204457|Sphingomonadales	204457|Sphingomonadales	O	COG0694 Thioredoxin-like proteins and domains	-	-	-	-	-	-	-	-	-	-	-	-	Nfu_N,NifU
CMS1_k127_1089336_0	1545915.JROG01000008_gene3369	0.0	1137.0	COG0612@1|root,COG0612@2|Bacteria,1NAH6@1224|Proteobacteria,2U0S5@28211|Alphaproteobacteria,2K0RS@204457|Sphingomonadales	204457|Sphingomonadales	S	Peptidase, M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
CMS1_k127_1089336_32	1248916.ANFY01000011_gene1068	1.083e-24	112.0	COG1225@1|root,COG1225@2|Bacteria,1MZN4@1224|Proteobacteria,2UA7Y@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS1_k127_1089336_2	1545915.JROG01000003_gene1180	1.139e-218	684.0	COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,2TRXC@28211|Alphaproteobacteria,2K0UP@204457|Sphingomonadales	204457|Sphingomonadales	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
CMS1_k127_1089336_18	1346791.M529_14340	1.006e-96	319.0	COG5405@1|root,COG5405@2|Bacteria,1MVF2@1224|Proteobacteria,2TRRE@28211|Alphaproteobacteria,2K0IZ@204457|Sphingomonadales	204457|Sphingomonadales	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
CMS1_k127_1089336_34	1123270.ATUR01000005_gene490	4.391e-13	72.0	2AMCF@1|root,31C7R@2|Bacteria,1P0RP@1224|Proteobacteria,2UVJW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1089336_36	1335760.ASTG01000006_gene1313	7.509e-07	53.0	2A38W@1|root,30RQQ@2|Bacteria,1P7V2@1224|Proteobacteria,2UY8R@28211|Alphaproteobacteria,2K7SE@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1089336_7	1120705.FG95_02057	2.716e-155	502.0	COG0477@1|root,COG2814@2|Bacteria,1QTWR@1224|Proteobacteria,2TW1S@28211|Alphaproteobacteria,2K09D@204457|Sphingomonadales	204457|Sphingomonadales	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_1089336_22	317655.Sala_1154	2.7e-88	295.0	COG0558@1|root,COG0558@2|Bacteria,1RCZ7@1224|Proteobacteria,2TUI7@28211|Alphaproteobacteria,2K47C@204457|Sphingomonadales	204457|Sphingomonadales	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	-	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
CMS1_k127_1089336_33	1346791.M529_10405	3.774e-18	93.0	COG1977@1|root,COG1977@2|Bacteria,1N0IE@1224|Proteobacteria,2UF4F@28211|Alphaproteobacteria,2K6UZ@204457|Sphingomonadales	204457|Sphingomonadales	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	moaD	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
CMS1_k127_1089336_30	1030157.AFMP01000019_gene712	7.724e-40	155.0	COG0314@1|root,COG0314@2|Bacteria,1RGUX@1224|Proteobacteria,2U73K@28211|Alphaproteobacteria,2K4HA@204457|Sphingomonadales	204457|Sphingomonadales	H	Molybdopterin converting factor, large subunit	moaE	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
CMS1_k127_1089336_10	452662.SJA_C1-22750	2.22e-146	468.0	COG0583@1|root,COG0583@2|Bacteria,1MVA1@1224|Proteobacteria,2TSUS@28211|Alphaproteobacteria,2K012@204457|Sphingomonadales	204457|Sphingomonadales	K	Transcriptional regulator	-	-	-	ko:K04761	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
CMS1_k127_1089336_16	317655.Sala_0528	6.071e-114	371.0	COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,2TQQ5@28211|Alphaproteobacteria,2K2GH@204457|Sphingomonadales	204457|Sphingomonadales	E	serine acetyltransferase	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep
CMS1_k127_1089336_29	1470591.BW41_02664	1.436e-45	167.0	2CCMQ@1|root,32RW3@2|Bacteria,1MZHB@1224|Proteobacteria,2UCC9@28211|Alphaproteobacteria,2K53Z@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF2794)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2794
CMS1_k127_1089336_13	627192.SLG_08880	7.409e-126	405.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,2TRFZ@28211|Alphaproteobacteria,2K0QB@204457|Sphingomonadales	204457|Sphingomonadales	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_1089336_21	317655.Sala_0822	2.462e-90	303.0	COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,2TQMN@28211|Alphaproteobacteria,2K0AA@204457|Sphingomonadales	204457|Sphingomonadales	P	Plays a role in the regulation of phosphate uptake	phoU	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
CMS1_k127_1089336_11	1545915.JROG01000004_gene2433	2.12e-141	452.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,2TQX9@28211|Alphaproteobacteria,2JZZN@204457|Sphingomonadales	204457|Sphingomonadales	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
CMS1_k127_1089336_6	1192759.AKIB01000011_gene2677	2.552e-170	544.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,2TQYQ@28211|Alphaproteobacteria,2JZYA@204457|Sphingomonadales	204457|Sphingomonadales	P	phosphate transport system permease	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,DUF3333
CMS1_k127_1089336_4	1123270.ATUR01000004_gene1590	5.974e-203	641.0	COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,2TQU1@28211|Alphaproteobacteria,2K16C@204457|Sphingomonadales	204457|Sphingomonadales	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,DUF3708
CMS1_k127_1089336_15	702113.PP1Y_AT7004	5.309e-121	394.0	COG0226@1|root,COG0226@2|Bacteria,1MUH9@1224|Proteobacteria,2TR1C@28211|Alphaproteobacteria,2K0M7@204457|Sphingomonadales	204457|Sphingomonadales	P	Phosphate ABC transporter substrate-binding protein	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
CMS1_k127_1141463_2	702113.PP1Y_AT22004	9.739e-64	219.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,2TRNX@28211|Alphaproteobacteria,2K03C@204457|Sphingomonadales	204457|Sphingomonadales	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
CMS1_k127_1141463_0	1123270.ATUR01000004_gene1786	7.069e-273	846.0	COG1232@1|root,COG1232@2|Bacteria,1MX35@1224|Proteobacteria,2TU7I@28211|Alphaproteobacteria,2K14D@204457|Sphingomonadales	204457|Sphingomonadales	H	Thi4 family	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
CMS1_k127_1141463_4	452662.SJA_C1-03040	5.119e-27	115.0	COG2246@1|root,COG2246@2|Bacteria,1NXH1@1224|Proteobacteria,2USV4@28211|Alphaproteobacteria,2K8CV@204457|Sphingomonadales	204457|Sphingomonadales	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
CMS1_k127_1141463_1	291985.CCSI01000002_gene1554	6.712e-157	511.0	COG1368@1|root,COG1368@2|Bacteria,1R6IX@1224|Proteobacteria	1224|Proteobacteria	M	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS1_k127_1141463_3	383381.EH30_14310	1.186e-49	185.0	COG1287@1|root,COG1287@2|Bacteria,1RCIB@1224|Proteobacteria,2TV2J@28211|Alphaproteobacteria,2KDNP@204457|Sphingomonadales	204457|Sphingomonadales	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1156685_20	1282876.BAOK01000001_gene2292	3.659e-99	325.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,2TSZZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG3653 N-acyl-D-aspartate D-glutamate deacylase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
CMS1_k127_1156685_9	383381.EH30_07180	1.326e-138	445.0	COG2267@1|root,COG2267@2|Bacteria,1QU7K@1224|Proteobacteria,2TW27@28211|Alphaproteobacteria,2KE98@204457|Sphingomonadales	204457|Sphingomonadales	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CMS1_k127_1156685_6	1120705.FG95_02495	1.124e-203	641.0	COG0493@1|root,COG0493@2|Bacteria,1P58U@1224|Proteobacteria,2TUCG@28211|Alphaproteobacteria,2K06F@204457|Sphingomonadales	204457|Sphingomonadales	E	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases	-	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	Pyr_redox_2
CMS1_k127_1156685_22	1545915.JROG01000004_gene2335	2.38e-89	304.0	COG3904@1|root,COG3904@2|Bacteria,1R6HZ@1224|Proteobacteria,2U0MS@28211|Alphaproteobacteria,2K184@204457|Sphingomonadales	204457|Sphingomonadales	S	periplasmic protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1156685_30	1502850.FG91_00509	4.167e-42	161.0	2C3YK@1|root,2ZHJ2@2|Bacteria,1RKGM@1224|Proteobacteria,2UBK5@28211|Alphaproteobacteria,2K5GJ@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1156685_21	1502850.FG91_01696	4.476e-94	319.0	COG3391@1|root,COG3391@2|Bacteria,1P862@1224|Proteobacteria,2TR6Z@28211|Alphaproteobacteria,2K2W8@204457|Sphingomonadales	204457|Sphingomonadales	S	Lactonase, 7-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1,Lactonase,PQQ_2
CMS1_k127_1156685_4	1545915.JROG01000003_gene1517	2.469e-251	792.0	COG2303@1|root,COG2303@2|Bacteria,1P9UF@1224|Proteobacteria,2U3F9@28211|Alphaproteobacteria,2K2U7@204457|Sphingomonadales	204457|Sphingomonadales	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
CMS1_k127_1156685_11	1044.EH31_13110	3.573e-130	418.0	COG3484@1|root,COG3484@2|Bacteria,1N057@1224|Proteobacteria,2U09K@28211|Alphaproteobacteria,2K318@204457|Sphingomonadales	204457|Sphingomonadales	O	proteasome-type protease	-	-	-	ko:K07395	-	-	-	-	ko00000	-	-	-	Proteasome
CMS1_k127_1156685_15	685035.ADAE01000003_gene2771	6.002e-108	361.0	COG1305@1|root,COG1305@2|Bacteria,1MVMI@1224|Proteobacteria,2TTZY@28211|Alphaproteobacteria,2K2SK@204457|Sphingomonadales	204457|Sphingomonadales	E	COG1305 Transglutaminase-like enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,Transglut_core
CMS1_k127_1156685_12	1174684.EBMC1_17327	7.427e-128	416.0	COG2307@1|root,COG2307@2|Bacteria,1MVZK@1224|Proteobacteria,2TQUM@28211|Alphaproteobacteria,2K13E@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E
CMS1_k127_1156685_3	1044.EH31_13125	5.481e-262	811.0	COG2308@1|root,COG2308@2|Bacteria,1MUAD@1224|Proteobacteria,2TRI7@28211|Alphaproteobacteria,2K23M@204457|Sphingomonadales	204457|Sphingomonadales	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
CMS1_k127_1156685_16	314231.FP2506_07471	2.436e-107	356.0	COG1028@1|root,COG1028@2|Bacteria,1P9R4@1224|Proteobacteria,2TTJ5@28211|Alphaproteobacteria,2PKQB@255475|Aurantimonadaceae	28211|Alphaproteobacteria	IQ	KR domain	-	-	1.3.1.33	ko:K00218	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03845,R06286	RC01008	ko00000,ko00001,ko01000	-	-	-	adh_short
CMS1_k127_1156685_25	291985.CCSI01000001_gene2664	1.843e-62	223.0	COG3338@1|root,COG3338@2|Bacteria,1PEA6@1224|Proteobacteria,2TVPG@28211|Alphaproteobacteria,2K8P6@204457|Sphingomonadales	204457|Sphingomonadales	P	Eukaryotic-type carbonic anhydrase	-	-	-	-	-	-	-	-	-	-	-	-	Carb_anhydrase
CMS1_k127_1156685_7	627192.SLG_36410	1.263e-190	600.0	COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,2TR9V@28211|Alphaproteobacteria,2K0B2@204457|Sphingomonadales	204457|Sphingomonadales	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
CMS1_k127_1156685_17	627192.SLG_11510	1.063e-106	357.0	COG4247@1|root,COG4247@2|Bacteria,1MVTA@1224|Proteobacteria,2TUDJ@28211|Alphaproteobacteria,2JZUY@204457|Sphingomonadales	204457|Sphingomonadales	I	3-phytase	phy	-	3.1.3.8	ko:K01083	ko00562,map00562	-	R03371	RC00078	ko00000,ko00001,ko01000	-	-	-	Phytase
CMS1_k127_1156685_0	685035.ADAE01000018_gene1057	0.0	1175.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MUWN@1224|Proteobacteria,2TUIR@28211|Alphaproteobacteria,2K0N7@204457|Sphingomonadales	204457|Sphingomonadales	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec
CMS1_k127_1156685_5	1174684.EBMC1_08891	2.203e-237	756.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria,2K0SK@204457|Sphingomonadales	204457|Sphingomonadales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,dCache_3
CMS1_k127_1156685_26	1545915.JROG01000001_gene236	1.308e-59	213.0	COG3794@1|root,COG3794@2|Bacteria,1RHQU@1224|Proteobacteria,2UBHY@28211|Alphaproteobacteria,2K4QK@204457|Sphingomonadales	204457|Sphingomonadales	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1156685_14	1545915.JROG01000001_gene237	3.901e-117	383.0	28JGK@1|root,2Z9AA@2|Bacteria,1MWFY@1224|Proteobacteria,2U3RX@28211|Alphaproteobacteria,2K0CC@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF3034)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3034
CMS1_k127_1156685_27	1174684.EBMC1_08906	1.11e-57	204.0	COG2346@1|root,COG2346@2|Bacteria,1N005@1224|Proteobacteria,2U8PT@28211|Alphaproteobacteria,2K4K8@204457|Sphingomonadales	204457|Sphingomonadales	S	Bacterial-like globin	-	-	-	-	-	-	-	-	-	-	-	-	Bac_globin
CMS1_k127_1156685_23	1248760.ANFZ01000018_gene758	8.288e-88	299.0	COG0500@1|root,COG2226@2|Bacteria,1PVPS@1224|Proteobacteria,2TREE@28211|Alphaproteobacteria,2JZZE@204457|Sphingomonadales	204457|Sphingomonadales	Q	ubiquinone menaquinone biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
CMS1_k127_1156685_2	1207055.C100_05675	0.0	1050.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,2TR3H@28211|Alphaproteobacteria,2K17X@204457|Sphingomonadales	204457|Sphingomonadales	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C
CMS1_k127_1156685_13	237727.NAP1_14733	5.021e-118	394.0	COG0531@1|root,COG0531@2|Bacteria,1MUA2@1224|Proteobacteria,2VG2Y@28211|Alphaproteobacteria,2K60F@204457|Sphingomonadales	204457|Sphingomonadales	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
CMS1_k127_1156685_19	1479239.JQMU01000001_gene625	6.301e-101	347.0	COG2271@1|root,COG2271@2|Bacteria,1R2YM@1224|Proteobacteria,2TZX8@28211|Alphaproteobacteria,2KBQH@204457|Sphingomonadales	1224|Proteobacteria	G	Acetyl-coenzyme A transporter 1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_1156685_29	1280949.HAD_14652	1.755e-49	184.0	2DN04@1|root,32UP0@2|Bacteria,1N3MR@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1156685_31	113395.AXAI01000008_gene1150	2.748e-31	140.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,3JR8W@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	TPR_16,TPR_8,Trans_reg_C
CMS1_k127_1156685_32	1248760.ANFZ01000013_gene1824	5.929e-17	81.0	2BBFK@1|root,324YV@2|Bacteria,1NF3M@1224|Proteobacteria,2UIN4@28211|Alphaproteobacteria,2K7VH@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1156685_8	1537715.JQFJ01000002_gene434	7.056e-161	520.0	COG3746@1|root,COG3746@2|Bacteria,1RA39@1224|Proteobacteria,2U0ZX@28211|Alphaproteobacteria,2K1KI@204457|Sphingomonadales	204457|Sphingomonadales	P	phosphate-selective porin	-	-	-	ko:K07221	-	-	-	-	ko00000,ko02000	1.B.5.1	-	-	Porin_O_P
CMS1_k127_1156685_24	1219045.BV98_000131	2.157e-78	271.0	COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,2TQMN@28211|Alphaproteobacteria,2K0AA@204457|Sphingomonadales	204457|Sphingomonadales	P	Plays a role in the regulation of phosphate uptake	phoU	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
CMS1_k127_1156685_10	158500.BV97_02619	2.55e-136	443.0	COG0226@1|root,COG0226@2|Bacteria,1MUH9@1224|Proteobacteria,2TR1C@28211|Alphaproteobacteria,2K0M7@204457|Sphingomonadales	204457|Sphingomonadales	P	Phosphate ABC transporter substrate-binding protein	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
CMS1_k127_1156685_28	1280948.HY36_07375	2.863e-52	191.0	COG0454@1|root,COG0456@2|Bacteria,1N1IQ@1224|Proteobacteria,2UEAW@28211|Alphaproteobacteria,43XSN@69657|Hyphomonadaceae	28211|Alphaproteobacteria	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7
CMS1_k127_1156685_1	1123269.NX02_22390	0.0	1116.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,2USBB@28211|Alphaproteobacteria,2K0P9@204457|Sphingomonadales	204457|Sphingomonadales	M	Penicillin-binding Protein	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	PCB_OB,Transgly,Transpeptidase
CMS1_k127_1156685_18	317655.Sala_3173	1.433e-101	334.0	COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,2U0K2@28211|Alphaproteobacteria,2K2BU@204457|Sphingomonadales	204457|Sphingomonadales	M	N-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
CMS1_k127_1159255_0	1174684.EBMC1_13618	4.725e-183	582.0	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,2TTV2@28211|Alphaproteobacteria,2K0E5@204457|Sphingomonadales	204457|Sphingomonadales	S	Peptidase M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TPR_16
CMS1_k127_1159255_2	1545915.JROG01000003_gene1183	1.885e-78	271.0	COG1651@1|root,COG1651@2|Bacteria,1MY3H@1224|Proteobacteria,2TTXR@28211|Alphaproteobacteria,2K3ZK@204457|Sphingomonadales	204457|Sphingomonadales	O	Protein-disulfide isomerase	-	-	-	-	-	-	-	-	-	-	-	-	DSBA,Thioredoxin_4
CMS1_k127_1159255_1	1248760.ANFZ01000008_gene1583	8.195e-107	349.0	COG0293@1|root,COG0293@2|Bacteria,1MW1C@1224|Proteobacteria,2TSBW@28211|Alphaproteobacteria,2K02A@204457|Sphingomonadales	204457|Sphingomonadales	J	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit	ftsJ	-	2.1.1.166	ko:K02427	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ
CMS1_k127_1207081_1	1335760.ASTG01000013_gene2496	1.697e-221	702.0	COG0642@1|root,COG2205@2|Bacteria,1MVY8@1224|Proteobacteria,2TS5B@28211|Alphaproteobacteria,2K08R@204457|Sphingomonadales	204457|Sphingomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_7
CMS1_k127_1207081_5	279238.Saro_2001	2.491e-30	125.0	COG0802@1|root,COG0802@2|Bacteria,1RGYU@1224|Proteobacteria,2UBQ9@28211|Alphaproteobacteria,2K5A7@204457|Sphingomonadales	204457|Sphingomonadales	S	ATPase or kinase	-	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
CMS1_k127_1207081_2	1346791.M529_10075	7.447e-124	411.0	COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,2TSJD@28211|Alphaproteobacteria,2K04R@204457|Sphingomonadales	204457|Sphingomonadales	S	Phosphotransferase	-	-	2.7.1.221	ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH
CMS1_k127_1207081_4	158500.BV97_00452	9.189e-92	307.0	COG1208@1|root,COG1208@2|Bacteria,1R9ZD@1224|Proteobacteria,2TU2V@28211|Alphaproteobacteria,2K1HH@204457|Sphingomonadales	204457|Sphingomonadales	JM	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)	-	-	2.7.7.99	ko:K00992	ko00520,ko01100,map00520,map01100	-	R11025	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3,NTP_transferase
CMS1_k127_1207081_0	1123270.ATUR01000006_gene44	2.561e-318	1003.0	COG2887@1|root,COG3893@1|root,COG2887@2|Bacteria,COG3893@2|Bacteria,1MY2G@1224|Proteobacteria,2TS74@28211|Alphaproteobacteria,2K06P@204457|Sphingomonadales	204457|Sphingomonadales	L	helicase	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1
CMS1_k127_1207081_3	1114964.L485_20290	5.71e-121	401.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,2TQJZ@28211|Alphaproteobacteria,2K07I@204457|Sphingomonadales	204457|Sphingomonadales	L	Belongs to the helicase family. UvrD subfamily	addA	-	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
CMS1_k127_1219582_1	1545915.JROG01000003_gene1252	1.963e-136	442.0	COG0584@1|root,COG0584@2|Bacteria,1MVWZ@1224|Proteobacteria,2TV4M@28211|Alphaproteobacteria,2K0H8@204457|Sphingomonadales	204457|Sphingomonadales	C	glycerophosphoryl diester phosphodiesterase	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
CMS1_k127_1219582_0	383381.EH30_05285	4.653e-143	459.0	COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,2TQT1@28211|Alphaproteobacteria,2K1CJ@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
CMS1_k127_1219582_2	1545915.JROG01000001_gene518	9.489e-77	265.0	COG4649@1|root,COG4649@2|Bacteria,1P2GI@1224|Proteobacteria,2UCFZ@28211|Alphaproteobacteria,2K40C@204457|Sphingomonadales	204457|Sphingomonadales	S	Tetratricopeptide repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	TPR_21
CMS1_k127_1219582_3	1123270.ATUR01000002_gene2610	8.502e-22	97.0	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,2TUAD@28211|Alphaproteobacteria,2K0GW@204457|Sphingomonadales	204457|Sphingomonadales	S	Pyrrolo-quinoline quinone	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
CMS1_k127_1232601_9	1333998.M2A_2423	2.445e-20	95.0	2E5ES@1|root,3306N@2|Bacteria,1N5VN@1224|Proteobacteria,2UD42@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1232601_7	1122970.AUHC01000012_gene891	2.012e-41	157.0	COG1525@1|root,COG1525@2|Bacteria,1MZNP@1224|Proteobacteria,2UCTJ@28211|Alphaproteobacteria,2K634@204457|Sphingomonadales	204457|Sphingomonadales	L	nuclease	-	-	-	-	-	-	-	-	-	-	-	-	SNase
CMS1_k127_1232601_6	1248917.ANFX01000019_gene2336	2.292e-116	379.0	COG1028@1|root,COG1028@2|Bacteria,1MWGC@1224|Proteobacteria,2TSNX@28211|Alphaproteobacteria,2K9H3@204457|Sphingomonadales	204457|Sphingomonadales	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
CMS1_k127_1232601_8	1174684.EBMC1_15649	1.533e-26	113.0	COG3134@1|root,COG3134@2|Bacteria,1NGQT@1224|Proteobacteria,2UMR2@28211|Alphaproteobacteria,2K745@204457|Sphingomonadales	204457|Sphingomonadales	S	Glycine zipper 2TM domain	-	-	-	-	-	-	-	-	-	-	-	-	Rick_17kDa_Anti
CMS1_k127_1232601_0	1248760.ANFZ01000021_gene376	0.0	2227.0	COG5276@1|root,COG5276@2|Bacteria,1R66X@1224|Proteobacteria,2U4DF@28211|Alphaproteobacteria,2K18I@204457|Sphingomonadales	204457|Sphingomonadales	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
CMS1_k127_1232601_2	1248760.ANFZ01000021_gene375	2.496e-298	930.0	COG3827@1|root,COG3827@2|Bacteria,1QQR0@1224|Proteobacteria,2U38X@28211|Alphaproteobacteria,2K2AW@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1232601_3	237727.NAP1_09592	1.727e-279	874.0	COG3193@1|root,COG3193@2|Bacteria,1R3RC@1224|Proteobacteria,2U39K@28211|Alphaproteobacteria,2K2UI@204457|Sphingomonadales	204457|Sphingomonadales	S	Haem-degrading	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
CMS1_k127_1232601_5	1545915.JROG01000003_gene1473	7.178e-203	641.0	COG3391@1|root,COG3391@2|Bacteria,1MXXH@1224|Proteobacteria,2TW31@28211|Alphaproteobacteria,2K2PG@204457|Sphingomonadales	204457|Sphingomonadales	S	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
CMS1_k127_1232601_4	1479239.JQMU01000001_gene710	9.697e-264	818.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TTJP@28211|Alphaproteobacteria,2K07M@204457|Sphingomonadales	204457|Sphingomonadales	C	belongs to the aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
CMS1_k127_1232601_1	1030157.AFMP01000028_gene2307	1.273e-301	929.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2TSB1@28211|Alphaproteobacteria,2K1IG@204457|Sphingomonadales	204457|Sphingomonadales	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS1_k127_1264178_4	1114964.L485_19660	1.921e-59	214.0	28H8Z@1|root,2Z7KS@2|Bacteria,1MW9T@1224|Proteobacteria,2U5RX@28211|Alphaproteobacteria,2K5KG@204457|Sphingomonadales	204457|Sphingomonadales	S	Yip1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Yip1
CMS1_k127_1264178_3	1470591.BW41_00418	1.593e-97	323.0	COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,2TT7W@28211|Alphaproteobacteria,2K1AX@204457|Sphingomonadales	204457|Sphingomonadales	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
CMS1_k127_1264178_1	1449076.JOOE01000001_gene2325	2.685e-228	728.0	COG0658@1|root,COG0658@2|Bacteria,1MUKF@1224|Proteobacteria,2TRD5@28211|Alphaproteobacteria,2K0XJ@204457|Sphingomonadales	204457|Sphingomonadales	S	membrane metal-binding protein	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131
CMS1_k127_1264178_2	1123269.NX02_24245	1.565e-219	691.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,2TRSU@28211|Alphaproteobacteria,2K09A@204457|Sphingomonadales	204457|Sphingomonadales	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX1	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
CMS1_k127_1264178_0	1248917.ANFX01000010_gene199	4.449e-249	773.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,2TS63@28211|Alphaproteobacteria,2K0JS@204457|Sphingomonadales	204457|Sphingomonadales	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
CMS1_k127_1264178_5	158500.BV97_00627	1.271e-45	168.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2U3HG@28211|Alphaproteobacteria,2K0AE@204457|Sphingomonadales	204457|Sphingomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
CMS1_k127_127057_1	194867.ALBQ01000034_gene1030	6.494e-89	308.0	COG4773@1|root,COG4773@2|Bacteria,1Q323@1224|Proteobacteria,2TW33@28211|Alphaproteobacteria,2K10M@204457|Sphingomonadales	204457|Sphingomonadales	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
CMS1_k127_127057_4	1123059.KB823013_gene460	4.974e-50	182.0	COG5622@1|root,COG5622@2|Bacteria,1N6UG@1224|Proteobacteria	1224|Proteobacteria	N	attachment protein	atsE	-	-	-	-	-	-	-	-	-	-	-	Host_attach
CMS1_k127_127057_3	1550073.JROH01000010_gene1277	1.704e-71	242.0	COG0048@1|root,COG0048@2|Bacteria,1RCWY@1224|Proteobacteria,2U70K@28211|Alphaproteobacteria,2K3W8@204457|Sphingomonadales	204457|Sphingomonadales	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
CMS1_k127_127057_2	627192.SLG_35690	1.574e-82	275.0	COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,2TSI8@28211|Alphaproteobacteria,2K0I9@204457|Sphingomonadales	204457|Sphingomonadales	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
CMS1_k127_127057_0	1219035.NT2_02_03230	0.0	1199.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,2TQVI@28211|Alphaproteobacteria,2K04N@204457|Sphingomonadales	204457|Sphingomonadales	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
CMS1_k127_1311287_2	1545915.JROG01000003_gene1068	4.163e-113	374.0	COG0019@1|root,COG0019@2|Bacteria,1MW3T@1224|Proteobacteria,2TVR1@28211|Alphaproteobacteria,2K0YP@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the Orn Lys Arg decarboxylase class-II family. NspC subfamily	-	-	4.1.1.96	ko:K13747	ko00330,ko01100,map00330,map01100	-	R09081,R09082	RC00299	ko00000,ko00001,ko01000	-	-	-	Orn_DAP_Arg_deC
CMS1_k127_1311287_0	1545915.JROG01000003_gene1067	7.564e-214	671.0	COG1748@1|root,COG1748@2|Bacteria,1NIU2@1224|Proteobacteria,2TRRQ@28211|Alphaproteobacteria,2K1EZ@204457|Sphingomonadales	204457|Sphingomonadales	E	Saccharopine dehydrogenase	-	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
CMS1_k127_1311287_1	1123270.ATUR01000003_gene699	8.753e-139	447.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2TQN9@28211|Alphaproteobacteria,2K27R@204457|Sphingomonadales	204457|Sphingomonadales	E	Threonine dehydratase	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS1_k127_1354784_0	392499.Swit_0265	0.0	1726.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,2TRHQ@28211|Alphaproteobacteria,2K19P@204457|Sphingomonadales	204457|Sphingomonadales	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
CMS1_k127_1354784_2	237727.NAP1_09512	1.086e-78	273.0	COG1975@1|root,COG1975@2|Bacteria,1MXKU@1224|Proteobacteria,2TUF3@28211|Alphaproteobacteria,2K17D@204457|Sphingomonadales	204457|Sphingomonadales	O	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
CMS1_k127_1354784_1	1550073.JROH01000012_gene2511	1.453e-116	384.0	COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,1MX3A@1224|Proteobacteria,2TUU6@28211|Alphaproteobacteria,2K0I3@204457|Sphingomonadales	204457|Sphingomonadales	QU	Periplasmic component of the Tol biopolymer transport system	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,PD40
CMS1_k127_1376720_6	627192.SLG_38270	2.564e-139	445.0	COG4108@1|root,COG4108@2|Bacteria,1MU7X@1224|Proteobacteria,2TRP5@28211|Alphaproteobacteria,2K0N8@204457|Sphingomonadales	204457|Sphingomonadales	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
CMS1_k127_1376720_3	1280948.HY36_00880	6.817e-153	494.0	COG2270@1|root,COG2270@2|Bacteria,1QUNG@1224|Proteobacteria,2TTIE@28211|Alphaproteobacteria,43X4U@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_1376720_13	1278073.MYSTI_00921	3.537e-06	58.0	COG2312@1|root,COG2312@2|Bacteria	2|Bacteria	S	response to antibiotic	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1376720_8	194867.ALBQ01000053_gene1853	9.664e-97	321.0	COG0500@1|root,COG2226@2|Bacteria,1MVSY@1224|Proteobacteria,2TTNQ@28211|Alphaproteobacteria,2K0KH@204457|Sphingomonadales	204457|Sphingomonadales	Q	Methionine biosynthesis protein MetW	metW	-	-	-	-	-	-	-	-	-	-	-	MetW
CMS1_k127_1376720_1	1449076.JOOE01000003_gene3649	1.939e-208	652.0	COG2021@1|root,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,2TQYA@28211|Alphaproteobacteria,2JZX2@204457|Sphingomonadales	204457|Sphingomonadales	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metXA	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
CMS1_k127_1376720_2	1537715.JQFJ01000002_gene2063	7.491e-154	513.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,2TQPN@28211|Alphaproteobacteria,2JZXY@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS1_k127_1376720_4	745310.G432_10455	1.286e-152	491.0	COG0287@1|root,COG0287@2|Bacteria,1QTZA@1224|Proteobacteria,2TS12@28211|Alphaproteobacteria,2K18X@204457|Sphingomonadales	204457|Sphingomonadales	E	Dual function enzyme catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate and the formation of tyrosine from arogenate	tyrC	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0047794,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.3.1.12,1.3.1.43	ko:K00220	ko00400,ko00401,ko01100,ko01110,ko01230,map00400,map00401,map01100,map01110,map01230	M00040	R00732,R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
CMS1_k127_1376720_5	1120705.FG95_02320	1.383e-145	470.0	COG1376@1|root,COG3409@1|root,COG1376@2|Bacteria,COG3409@2|Bacteria,1MVI4@1224|Proteobacteria,2TSSC@28211|Alphaproteobacteria,2K1UG@204457|Sphingomonadales	204457|Sphingomonadales	M	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,YkuD
CMS1_k127_1376720_0	314285.KT71_14039	7.591e-257	798.0	COG2271@1|root,COG2271@2|Bacteria,1MWYR@1224|Proteobacteria,1SMB5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Organic Anion Transporter Polypeptide (OATP) family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_1376720_11	13690.CP98_04469	6.477e-68	238.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,2TT3P@28211|Alphaproteobacteria,2K3XJ@204457|Sphingomonadales	204457|Sphingomonadales	I	Acyltransferase	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
CMS1_k127_1376720_12	1030157.AFMP01000014_gene3384	8.845e-59	208.0	COG1434@1|root,COG1434@2|Bacteria,1RHMV@1224|Proteobacteria,2U957@28211|Alphaproteobacteria,2K4KS@204457|Sphingomonadales	204457|Sphingomonadales	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
CMS1_k127_1376720_9	517722.AEUE01000008_gene27	7.334e-79	274.0	COG2177@1|root,COG2177@2|Bacteria,1MXKQ@1224|Proteobacteria,2TSNT@28211|Alphaproteobacteria,2K43P@204457|Sphingomonadales	204457|Sphingomonadales	D	Cell division protein	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
CMS1_k127_1376720_7	1123270.ATUR01000004_gene1459	2.508e-122	397.0	COG2884@1|root,COG2884@2|Bacteria,1MVQ4@1224|Proteobacteria,2TS9Y@28211|Alphaproteobacteria,2JZVB@204457|Sphingomonadales	204457|Sphingomonadales	D	cell division	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
CMS1_k127_1376720_10	1123270.ATUR01000004_gene1460	1.6e-72	252.0	2E521@1|root,32ZVA@2|Bacteria,1RF95@1224|Proteobacteria,2U8QW@28211|Alphaproteobacteria,2K2DR@204457|Sphingomonadales	204457|Sphingomonadales	S	zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_4
CMS1_k127_1376720_14	1408427.JADB01000003_gene1273	7.611e-06	51.0	2AE9K@1|root,3143S@2|Bacteria,1PTGX@1224|Proteobacteria,2V5CG@28211|Alphaproteobacteria,48UFM@772|Bartonellaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1380426_4	1248760.ANFZ01000006_gene2479	1.594e-97	322.0	COG2084@1|root,COG2084@2|Bacteria,1RA7F@1224|Proteobacteria,2UVAZ@28211|Alphaproteobacteria,2K1F0@204457|Sphingomonadales	204457|Sphingomonadales	I	Belongs to the 3-hydroxyisobutyrate dehydrogenase family	mmsB	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
CMS1_k127_1380426_3	1537715.JQFJ01000002_gene2144	4.202e-136	437.0	COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,2TRYS@28211|Alphaproteobacteria,2K12I@204457|Sphingomonadales	204457|Sphingomonadales	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS1_k127_1380426_1	1537715.JQFJ01000002_gene2143	6.23e-167	530.0	COG1024@1|root,COG1024@2|Bacteria,1MU0B@1224|Proteobacteria,2TQW3@28211|Alphaproteobacteria,2K1J0@204457|Sphingomonadales	204457|Sphingomonadales	I	enoyl-CoA hydratase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_2
CMS1_k127_1380426_0	1331060.RLDS_08670	9.912e-214	668.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TQKE@28211|Alphaproteobacteria,2JZVG@204457|Sphingomonadales	204457|Sphingomonadales	I	acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS1_k127_1380426_2	314225.ELI_09665	2.122e-142	462.0	COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,2TR5C@28211|Alphaproteobacteria,2K0GT@204457|Sphingomonadales	204457|Sphingomonadales	E	Zn-dependent dipeptidase, microsomal dipeptidase	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
CMS1_k127_1380426_5	1449076.JOOE01000002_gene1387	1.008e-92	316.0	COG0726@1|root,COG0726@2|Bacteria,1PQ5E@1224|Proteobacteria,2TVJI@28211|Alphaproteobacteria,2K37W@204457|Sphingomonadales	204457|Sphingomonadales	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
CMS1_k127_1380426_7	317655.Sala_3051	4.315e-23	101.0	2DR05@1|root,339MI@2|Bacteria,1NHD4@1224|Proteobacteria,2VBVW@28211|Alphaproteobacteria,2K749@204457|Sphingomonadales	204457|Sphingomonadales	S	Peptidase inhibitor I78 family	-	-	-	-	-	-	-	-	-	-	-	-	Inhibitor_I78
CMS1_k127_1380426_6	1123270.ATUR01000002_gene2337	5.454e-25	103.0	COG1012@1|root,COG1012@2|Bacteria,1MUHV@1224|Proteobacteria,2TSMD@28211|Alphaproteobacteria,2K04G@204457|Sphingomonadales	204457|Sphingomonadales	C	Methylmalonate-semialdehyde dehydrogenase	mmsA	-	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS1_k127_1392913_1	383381.EH30_10135	1.494e-223	698.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,2TQWP@28211|Alphaproteobacteria,2K18S@204457|Sphingomonadales	204457|Sphingomonadales	E	gamma-glutamyltransferase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
CMS1_k127_1392913_6	627192.SLG_00280	9.107e-54	199.0	COG1416@1|root,COG1416@2|Bacteria,1RI2V@1224|Proteobacteria,2U98Z@28211|Alphaproteobacteria,2K5CI@204457|Sphingomonadales	204457|Sphingomonadales	S	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
CMS1_k127_1392913_5	1522072.IL54_4267	1.218e-97	323.0	COG3568@1|root,COG3568@2|Bacteria,1MVN7@1224|Proteobacteria,2U1MH@28211|Alphaproteobacteria,2K0EG@204457|Sphingomonadales	204457|Sphingomonadales	L	endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CMS1_k127_1392913_0	1248760.ANFZ01000018_gene533	0.0	1001.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,2TR2C@28211|Alphaproteobacteria,2K1TD@204457|Sphingomonadales	204457|Sphingomonadales	C	Belongs to the heme-copper respiratory oxidase family	ccoN	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
CMS1_k127_1392913_4	627192.SLG_38390	9.324e-123	398.0	COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,2TRGW@28211|Alphaproteobacteria,2K220@204457|Sphingomonadales	204457|Sphingomonadales	C	Peptidase S41	ccoO	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixO
CMS1_k127_1392913_7	1174684.EBMC1_04959	1.243e-12	70.0	COG4736@1|root,COG4736@2|Bacteria,1NGV0@1224|Proteobacteria,2UJBS@28211|Alphaproteobacteria,2K7TM@204457|Sphingomonadales	204457|Sphingomonadales	O	Cbb3-type cytochrome oxidase component FixQ	-	-	-	ko:K00407	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixQ
CMS1_k127_1392913_3	627192.SLG_38370	6.31e-135	437.0	COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,2TQW1@28211|Alphaproteobacteria,2K23A@204457|Sphingomonadales	204457|Sphingomonadales	C	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrom_C,Cytochrome_CBB3,FixP_N
CMS1_k127_1392913_2	1174684.EBMC1_04969	2.389e-146	466.0	COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,2TRYB@28211|Alphaproteobacteria,2K0BY@204457|Sphingomonadales	204457|Sphingomonadales	C	Nitrogen fixation protein fixG	ccoG	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
CMS1_k127_1447260_1	1123059.KB823011_gene1579	5.753e-173	556.0	COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,2TRC2@28211|Alphaproteobacteria,43WGX@69657|Hyphomonadaceae	28211|Alphaproteobacteria	I	COG4770 Acetyl propionyl-CoA carboxylase, alpha subunit	MA20_22950	-	6.4.1.5	ko:K13777	ko00281,map00281	-	R03494	RC00367,RC00942	ko00000,ko00001,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
CMS1_k127_1447260_2	999550.KI421507_gene2688	1.018e-165	529.0	COG2070@1|root,COG2070@2|Bacteria,1MU2F@1224|Proteobacteria,2TRM9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	2-nitropropane dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
CMS1_k127_1447260_3	314287.GB2207_05719	1.168e-109	368.0	COG1804@1|root,COG1804@2|Bacteria,1REXE@1224|Proteobacteria,1SNZ3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	carnitine dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
CMS1_k127_1447260_0	876044.IMCC3088_111	1.82e-191	612.0	COG0318@1|root,COG0318@2|Bacteria,1MVJ1@1224|Proteobacteria,1RS4E@1236|Gammaproteobacteria,1J5NR@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
CMS1_k127_1481369_0	627192.SLG_18070	1.677e-243	755.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2TS7G@28211|Alphaproteobacteria,2K0YK@204457|Sphingomonadales	204457|Sphingomonadales	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
CMS1_k127_1481369_2	1248917.ANFX01000024_gene1148	1.144e-36	145.0	COG3824@1|root,COG3824@2|Bacteria,1N18M@1224|Proteobacteria,2UBUK@28211|Alphaproteobacteria,2K6IY@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
CMS1_k127_1481369_1	1123270.ATUR01000006_gene113	1.701e-242	756.0	COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria,2VF3C@28211|Alphaproteobacteria,2KDVP@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
CMS1_k127_1481369_3	1248760.ANFZ01000009_gene1175	5.923e-21	93.0	COG1432@1|root,COG1432@2|Bacteria,1MX5C@1224|Proteobacteria,2TRE6@28211|Alphaproteobacteria,2K1CX@204457|Sphingomonadales	204457|Sphingomonadales	S	OST-HTH/LOTUS domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
CMS1_k127_1546433_4	1453503.AU05_24645	8.919e-47	172.0	COG4420@1|root,COG4420@2|Bacteria,1RIDY@1224|Proteobacteria,1SA4M@1236|Gammaproteobacteria,1YJ0B@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1003)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1003
CMS1_k127_1546433_2	1537715.JQFJ01000002_gene963	2.723e-69	251.0	COG0252@1|root,COG0252@2|Bacteria,1RHAW@1224|Proteobacteria,2UFQ1@28211|Alphaproteobacteria,2K4ZM@204457|Sphingomonadales	204457|Sphingomonadales	EJ	Asparaginase, N-terminal	-	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
CMS1_k127_1546433_1	1123270.ATUR01000002_gene2091	7.51e-261	811.0	COG1384@1|root,COG1384@2|Bacteria,1MV32@1224|Proteobacteria,2TQYH@28211|Alphaproteobacteria,2K1S0@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04566	ko00970,map00970	M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1f
CMS1_k127_1546433_3	998674.ATTE01000001_gene731	5.718e-50	202.0	COG4094@1|root,COG4094@2|Bacteria,1RDHB@1224|Proteobacteria,1S78U@1236|Gammaproteobacteria,4634E@72273|Thiotrichales	72273|Thiotrichales	S	NnrU protein	-	-	-	-	-	-	-	-	-	-	-	-	NnrU
CMS1_k127_1546433_0	1123270.ATUR01000002_gene2092	9.827e-305	945.0	COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,2TUKS@28211|Alphaproteobacteria,2K15X@204457|Sphingomonadales	204457|Sphingomonadales	KL	Helicase	dinG	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Helicase_C_2
CMS1_k127_1568248_2	1174684.EBMC1_03000	2.678e-30	122.0	COG1925@1|root,COG1925@2|Bacteria,1N6RM@1224|Proteobacteria,2UC0H@28211|Alphaproteobacteria,2K638@204457|Sphingomonadales	204457|Sphingomonadales	G	COG1925 Phosphotransferase system, HPr-related proteins	ptsH	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
CMS1_k127_1568248_0	1522072.IL54_0686	3.764e-119	389.0	COG0566@1|root,COG0566@2|Bacteria,1MWBE@1224|Proteobacteria,2TT4Y@28211|Alphaproteobacteria,2K16F@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
CMS1_k127_1568248_3	1537715.JQFJ01000002_gene2274	1.88e-11	70.0	COG3187@1|root,COG3650@1|root,COG3187@2|Bacteria,COG3650@2|Bacteria,1MXIV@1224|Proteobacteria,2U2HT@28211|Alphaproteobacteria,2K6CZ@204457|Sphingomonadales	204457|Sphingomonadales	O	META domain	-	-	-	-	-	-	-	-	-	-	-	-	META
CMS1_k127_1568248_1	1545915.JROG01000001_gene523	1.795e-90	300.0	COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,2TTX6@28211|Alphaproteobacteria,2K0B3@204457|Sphingomonadales	204457|Sphingomonadales	S	DNA recombination protein	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
CMS1_k127_1626491_2	194867.ALBQ01000059_gene3290	4.853e-88	292.0	COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,2TT6Q@28211|Alphaproteobacteria,2K0UK@204457|Sphingomonadales	204457|Sphingomonadales	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
CMS1_k127_1626491_1	1545915.JROG01000003_gene629	1.121e-92	309.0	COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,2U5P0@28211|Alphaproteobacteria,2K122@204457|Sphingomonadales	204457|Sphingomonadales	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
CMS1_k127_1626491_5	1288.SXYLSMQ121_0266	3.058e-32	136.0	COG1946@1|root,COG1946@2|Bacteria,1V302@1239|Firmicutes,4HG3J@91061|Bacilli,4GYQ6@90964|Staphylococcaceae	91061|Bacilli	I	Thioesterase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_3
CMS1_k127_1626491_4	1123270.ATUR01000010_gene1937	4.209e-65	235.0	COG3735@1|root,COG3735@2|Bacteria,1MVCW@1224|Proteobacteria,2U3RF@28211|Alphaproteobacteria,2K4KP@204457|Sphingomonadales	204457|Sphingomonadales	S	TraB family	-	-	-	ko:K09973	-	-	-	-	ko00000	-	-	-	TraB
CMS1_k127_1626491_3	1007104.SUS17_3494	9.331e-81	281.0	COG3735@1|root,COG3735@2|Bacteria,1MVCW@1224|Proteobacteria,2U5RA@28211|Alphaproteobacteria,2JZWN@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	ko:K09973	-	-	-	-	ko00000	-	-	-	TraB
CMS1_k127_1626491_0	314225.ELI_05855	1.336e-249	781.0	COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,2TQYD@28211|Alphaproteobacteria,2K1FR@204457|Sphingomonadales	204457|Sphingomonadales	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CMS1_k127_1653641_4	1537715.JQFJ01000002_gene1455	3.232e-37	145.0	COG0584@1|root,COG0584@2|Bacteria,1MVWZ@1224|Proteobacteria,2TV4M@28211|Alphaproteobacteria,2K0H8@204457|Sphingomonadales	204457|Sphingomonadales	C	glycerophosphoryl diester phosphodiesterase	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
CMS1_k127_1653641_5	1123322.KB904671_gene2857	3.255e-36	142.0	COG2343@1|root,COG2343@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF427)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
CMS1_k127_1653641_3	391615.ABSJ01000017_gene1630	6.835e-40	153.0	COG1393@1|root,COG1393@2|Bacteria,1MZ6S@1224|Proteobacteria,1S8TR@1236|Gammaproteobacteria,1J6PT@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Belongs to the ArsC family	yffB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC
CMS1_k127_1653641_0	314225.ELI_11695	9.003e-113	369.0	COG0177@1|root,COG0177@2|Bacteria,1R948@1224|Proteobacteria,2U3NR@28211|Alphaproteobacteria,2K9VX@204457|Sphingomonadales	204457|Sphingomonadales	L	FES	-	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
CMS1_k127_1653641_1	237727.NAP1_14388	1.895e-94	316.0	COG0177@1|root,COG0177@2|Bacteria,1N3XG@1224|Proteobacteria,2UDF8@28211|Alphaproteobacteria,2K670@204457|Sphingomonadales	204457|Sphingomonadales	L	endonuclease III	-	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
CMS1_k127_1653641_2	1081640.AGFU01000033_gene2969	1.401e-47	173.0	COG0454@1|root,COG0456@2|Bacteria,1RA6D@1224|Proteobacteria,2UC27@28211|Alphaproteobacteria,2K5HT@204457|Sphingomonadales	204457|Sphingomonadales	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS1_k127_1653641_6	279238.Saro_1431	1.743e-16	78.0	COG0604@1|root,COG0604@2|Bacteria,1MXUX@1224|Proteobacteria,2TTWF@28211|Alphaproteobacteria,2K2II@204457|Sphingomonadales	204457|Sphingomonadales	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_1660457_0	291985.CCSI01000003_gene113	0.0	1229.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,2TS9E@28211|Alphaproteobacteria,2K0N3@204457|Sphingomonadales	204457|Sphingomonadales	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
CMS1_k127_1660457_3	1044.EH31_09490	8.267e-77	263.0	COG1024@1|root,COG1024@2|Bacteria,1N2V7@1224|Proteobacteria,2U4VQ@28211|Alphaproteobacteria,2KC7U@204457|Sphingomonadales	204457|Sphingomonadales	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS1_k127_1660457_1	1537715.JQFJ01000002_gene447	2.209e-281	881.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MWGR@1224|Proteobacteria,2TUXY@28211|Alphaproteobacteria,2K16Q@204457|Sphingomonadales	204457|Sphingomonadales	EU	peptidase S9	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
CMS1_k127_1660457_5	1174684.EBMC1_11470	1.946e-17	89.0	COG3827@1|root,COG3827@2|Bacteria,1MX61@1224|Proteobacteria,2TSG8@28211|Alphaproteobacteria,2K7EP@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	ko:K09991	-	-	-	-	ko00000	-	-	-	DUF2497
CMS1_k127_1660457_2	1248760.ANFZ01000002_gene3159	9.04e-184	586.0	COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,2TR3S@28211|Alphaproteobacteria,2JZY5@204457|Sphingomonadales	204457|Sphingomonadales	MU	membrane	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
CMS1_k127_1660457_4	1123269.NX02_14120	2.65e-54	198.0	COG2518@1|root,COG2518@2|Bacteria,1RD6S@1224|Proteobacteria,2U704@28211|Alphaproteobacteria,2K2P0@204457|Sphingomonadales	204457|Sphingomonadales	O	protein-L-isoaspartate	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
CMS1_k127_1660457_6	190650.CC_2380	1.308e-05	52.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
CMS1_k127_1668291_9	1545915.JROG01000010_gene2892	5.489e-43	159.0	COG2020@1|root,COG2020@2|Bacteria,1R55E@1224|Proteobacteria,2U75X@28211|Alphaproteobacteria,2K0AU@204457|Sphingomonadales	204457|Sphingomonadales	O	protein-S-isoprenylcysteine methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295,ICMT
CMS1_k127_1668291_5	207954.MED92_03218	2.809e-80	271.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,1S25K@1236|Gammaproteobacteria,1XJCI@135619|Oceanospirillales	135619|Oceanospirillales	L	DNA-3-methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
CMS1_k127_1668291_3	1379701.JPJC01000007_gene3498	2.51e-87	305.0	COG4325@1|root,COG4325@2|Bacteria,1MXTM@1224|Proteobacteria,2TRWI@28211|Alphaproteobacteria,2K16G@204457|Sphingomonadales	204457|Sphingomonadales	S	Predicted membrane protein (DUF2254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2254
CMS1_k127_1668291_8	1479239.JQMU01000001_gene2368	8.729e-47	177.0	COG0454@1|root,COG0456@2|Bacteria,1QWIU@1224|Proteobacteria,2TWYI@28211|Alphaproteobacteria,2KEG9@204457|Sphingomonadales	204457|Sphingomonadales	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS1_k127_1668291_2	1331060.RLDS_16225	3.51e-120	392.0	COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,2TR7U@28211|Alphaproteobacteria,2KCMN@204457|Sphingomonadales	204457|Sphingomonadales	M	COG0668 Small-conductance mechanosensitive channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel,TM_helix
CMS1_k127_1668291_0	1144305.PMI02_03400	1.25e-161	521.0	COG1502@1|root,COG1502@2|Bacteria,1MV8I@1224|Proteobacteria,2TTM4@28211|Alphaproteobacteria,2K0U2@204457|Sphingomonadales	204457|Sphingomonadales	I	COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	PLDc,PLDc_2
CMS1_k127_1668291_7	1537715.JQFJ01000005_gene97	1.075e-48	177.0	COG2149@1|root,COG2149@2|Bacteria,1N3XC@1224|Proteobacteria,2UBS7@28211|Alphaproteobacteria,2K64S@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF202)	-	-	-	-	-	-	-	-	-	-	-	-	DUF202
CMS1_k127_1668291_11	391595.RLO149_c001040	8.91e-19	87.0	2EGMT@1|root,33ADY@2|Bacteria,1NH3I@1224|Proteobacteria,2UFRY@28211|Alphaproteobacteria,2P3W8@2433|Roseobacter	28211|Alphaproteobacteria	S	Phospholipase_D-nuclease N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_N
CMS1_k127_1668291_10	1112212.JH584236_gene27	4.269e-22	101.0	COG1295@1|root,COG1633@1|root,COG1295@2|Bacteria,COG1633@2|Bacteria,1MXQA@1224|Proteobacteria,2TSFP@28211|Alphaproteobacteria,2K0P0@204457|Sphingomonadales	204457|Sphingomonadales	S	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	HAD_2,Virul_fac_BrkB
CMS1_k127_1668291_1	1219045.BV98_002739	6.036e-132	436.0	COG0668@1|root,COG2823@1|root,COG0668@2|Bacteria,COG2823@2|Bacteria,1MW1F@1224|Proteobacteria,2TTVC@28211|Alphaproteobacteria,2K24E@204457|Sphingomonadales	204457|Sphingomonadales	M	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON,MS_channel
CMS1_k127_1668291_13	1537715.JQFJ01000002_gene1562	9.795e-18	89.0	COG3431@1|root,COG3431@2|Bacteria,1N6PE@1224|Proteobacteria,2UFF4@28211|Alphaproteobacteria,2K5XV@204457|Sphingomonadales	204457|Sphingomonadales	S	Sensors of blue-light using FAD	-	-	-	-	-	-	-	-	-	-	-	-	BLUF
CMS1_k127_1668291_6	1007104.SUS17_2292	3.022e-67	235.0	COG1595@1|root,COG1595@2|Bacteria,1MZMC@1224|Proteobacteria,2TUUZ@28211|Alphaproteobacteria,2K0TM@204457|Sphingomonadales	204457|Sphingomonadales	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_1668291_4	392499.Swit_3925	3.333e-87	296.0	COG0784@1|root,COG1595@1|root,COG0784@2|Bacteria,COG1595@2|Bacteria,1MX3Y@1224|Proteobacteria,2TT2R@28211|Alphaproteobacteria,2K0S1@204457|Sphingomonadales	204457|Sphingomonadales	T	In Caulobacter crescentus, CC3477 is differentially expressed in minimal salts media with glucose as compared to complex media	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Sigma70_r4_2
CMS1_k127_1668291_14	1282876.BAOK01000001_gene3089	0.0006963	48.0	COG4575@1|root,COG4575@2|Bacteria,1NGZU@1224|Proteobacteria	1224|Proteobacteria	S	Bacterial protein of unknown function (DUF883)	-	-	-	-	-	-	-	-	-	-	-	-	DUF883
CMS1_k127_1668291_12	1312954.KI914883_gene1538	3.852e-18	86.0	COG3871@1|root,COG3871@2|Bacteria,2IM6Z@201174|Actinobacteria	201174|Actinobacteria	S	pyridoxamine 5-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	Pyrid_ox_like
CMS1_k127_16777_2	1123269.NX02_25810	9.894e-109	361.0	COG4547@1|root,COG4547@2|Bacteria,1MX11@1224|Proteobacteria,2TS4N@28211|Alphaproteobacteria,2JZUK@204457|Sphingomonadales	204457|Sphingomonadales	H	Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide 5, 6-dimethylbenzimidazole phosphoribosyltransferase)	-	-	6.6.1.2	ko:K09883	ko00860,ko01100,map00860,map01100	-	R05227	RC02000	ko00000,ko00001,ko01000	-	-	-	CobT,CobT_C
CMS1_k127_16777_0	1248760.ANFZ01000009_gene1553	1.335e-273	858.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,2TQQ8@28211|Alphaproteobacteria,2K0XK@204457|Sphingomonadales	204457|Sphingomonadales	M	Penicillin-binding Protein	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
CMS1_k127_16777_1	1123270.ATUR01000002_gene2294	2.215e-190	597.0	COG0714@1|root,COG0714@2|Bacteria,1MXIW@1224|Proteobacteria,2TS1Z@28211|Alphaproteobacteria,2K0S6@204457|Sphingomonadales	204457|Sphingomonadales	S	Aerobic cobaltochelatase subunit CobS	-	-	6.6.1.2	ko:K09882	ko00860,ko01100,map00860,map01100	-	R05227	RC02000	ko00000,ko00001,ko01000	-	-	-	AAA_5,CbbQ_C,CobS_N
CMS1_k127_16777_3	629773.AORY01000004_gene23	5.406e-17	82.0	COG2214@1|root,COG2214@2|Bacteria,1MXTG@1224|Proteobacteria,2TRZH@28211|Alphaproteobacteria,2K4VC@204457|Sphingomonadales	204457|Sphingomonadales	O	molecular chaperone	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
CMS1_k127_1698141_1	1234595.C725_1408	7.112e-242	760.0	COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,2TRC2@28211|Alphaproteobacteria,4BPR1@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	I	Biotin carboxylase C-terminal domain	pccA	GO:0003674,GO:0003824,GO:0004658,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009374,GO:0009987,GO:0016421,GO:0016874,GO:0016885,GO:0017144,GO:0019752,GO:0019842,GO:0019899,GO:0031406,GO:0031974,GO:0032787,GO:0033218,GO:0033293,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0070013,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901681	6.4.1.3	ko:K01965	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
CMS1_k127_1698141_0	685035.ADAE01000018_gene714	1.002e-258	806.0	COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,2TRAP@28211|Alphaproteobacteria,2K0IY@204457|Sphingomonadales	204457|Sphingomonadales	EGP	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
CMS1_k127_1698141_2	1123270.ATUR01000003_gene670	4.448e-92	314.0	COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,2TQKD@28211|Alphaproteobacteria,2K0BU@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
CMS1_k127_1748777_3	1123270.ATUR01000007_gene1325	2.091e-123	398.0	COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,2TQKQ@28211|Alphaproteobacteria,2K0FF@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the GMC oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N,Lycopene_cycl
CMS1_k127_1748777_2	1307437.J139_11409	4.805e-162	525.0	COG0591@1|root,COG0591@2|Bacteria,1R4VK@1224|Proteobacteria,1RQFS@1236|Gammaproteobacteria,2PZK0@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	E	Sodium:solute symporter family	nanT	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
CMS1_k127_1748777_1	1088721.NSU_1934	1.941e-227	710.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,2TT2J@28211|Alphaproteobacteria,2K0PX@204457|Sphingomonadales	204457|Sphingomonadales	P	Ammonium Transporter	amt	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
CMS1_k127_1748777_7	1545915.JROG01000004_gene1733	1.291e-49	180.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2U952@28211|Alphaproteobacteria,2K4EF@204457|Sphingomonadales	204457|Sphingomonadales	K	Belongs to the P(II) protein family	-	-	-	ko:K04752	-	-	-	-	ko00000	-	-	-	P-II
CMS1_k127_1748777_5	392499.Swit_1920	1.013e-75	272.0	COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,2TVQR@28211|Alphaproteobacteria,2K876@204457|Sphingomonadales	204457|Sphingomonadales	T	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin,cNMP_binding
CMS1_k127_1748777_4	685035.ADAE01000023_gene1705	3.502e-90	299.0	COG3576@1|root,COG3576@2|Bacteria,1R8RC@1224|Proteobacteria,2TUXH@28211|Alphaproteobacteria,2K323@204457|Sphingomonadales	204457|Sphingomonadales	S	Pfam:Pyridox_oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
CMS1_k127_1748777_8	1234595.C725_1377	1.19e-20	99.0	COG4449@1|root,COG4449@2|Bacteria,1NIUY@1224|Proteobacteria,2UFGU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
CMS1_k127_1748777_6	392499.Swit_1919	2.188e-55	199.0	COG3803@1|root,COG3803@2|Bacteria,1RHYI@1224|Proteobacteria,2U7AN@28211|Alphaproteobacteria,2K570@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF924
CMS1_k127_1748777_0	1248760.ANFZ01000011_gene287	5.749e-244	757.0	COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,2TRSR@28211|Alphaproteobacteria,2JZY8@204457|Sphingomonadales	204457|Sphingomonadales	S	peptidase U62, modulator of DNA gyrase	tldD	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
CMS1_k127_1800789_1	1123270.ATUR01000003_gene775	4.999e-137	444.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,2TS31@28211|Alphaproteobacteria,2K1MM@204457|Sphingomonadales	204457|Sphingomonadales	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	bkdB	-	2.3.1.168	ko:K09699	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R02662,R03174,R04097,R10998	RC00004,RC02727,RC02870	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
CMS1_k127_1800789_0	1174684.EBMC1_16399	0.0	2033.0	COG3485@1|root,COG3485@2|Bacteria,1QUNE@1224|Proteobacteria,2U26Y@28211|Alphaproteobacteria,2K38K@204457|Sphingomonadales	204457|Sphingomonadales	Q	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
CMS1_k127_1800789_2	1174684.EBMC1_16404	4.712e-69	248.0	COG4719@1|root,COG4719@2|Bacteria,1R87U@1224|Proteobacteria,2U4JA@28211|Alphaproteobacteria,2K3HI@204457|Sphingomonadales	204457|Sphingomonadales	S	TIGRFAM conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
CMS1_k127_1800789_3	1174684.EBMC1_16409	1.314e-35	138.0	COG4719@1|root,COG4719@2|Bacteria,1N2CR@1224|Proteobacteria,2UE4C@28211|Alphaproteobacteria,2KE4M@204457|Sphingomonadales	204457|Sphingomonadales	S	TIGRFAM conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
CMS1_k127_1800892_1	13690.CP98_01608	3.911e-127	411.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,2TRW2@28211|Alphaproteobacteria,2K0TK@204457|Sphingomonadales	204457|Sphingomonadales	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
CMS1_k127_1800892_3	1248760.ANFZ01000024_gene1697	2.615e-57	203.0	COG1495@1|root,COG1495@2|Bacteria,1N89I@1224|Proteobacteria,2UF49@28211|Alphaproteobacteria,2K59V@204457|Sphingomonadales	204457|Sphingomonadales	O	Disulfide bond formation protein	-	-	-	-	-	-	-	-	-	-	-	-	DsbB
CMS1_k127_1800892_2	1502850.FG91_01597	2.599e-66	230.0	COG2941@1|root,COG2941@2|Bacteria,1RAK4@1224|Proteobacteria,2U85I@28211|Alphaproteobacteria,2K46W@204457|Sphingomonadales	204457|Sphingomonadales	H	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol	coq7	-	-	ko:K06134	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00128	R04984,R08775	RC01254	ko00000,ko00001,ko00002,ko01000	-	-	-	COQ7
CMS1_k127_1800892_4	1331060.RLDS_20875	1.738e-43	166.0	2BJB4@1|root,32DM3@2|Bacteria,1N0RM@1224|Proteobacteria,2UC21@28211|Alphaproteobacteria,2K68N@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1800892_0	1123270.ATUR01000008_gene238	6.071e-255	796.0	COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,2TSQN@28211|Alphaproteobacteria,2KCC8@204457|Sphingomonadales	204457|Sphingomonadales	C	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
CMS1_k127_1807565_5	1219035.NT2_02_00860	2.624e-37	140.0	COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,1MVU6@1224|Proteobacteria,2TS0R@28211|Alphaproteobacteria,2K0PG@204457|Sphingomonadales	204457|Sphingomonadales	C	Electron transfer flavoprotein-ubiquinone oxidoreductase	-	-	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	ETF_QO,FAD_binding_2,NAD_binding_8
CMS1_k127_1807565_2	1207055.C100_14740	3.136e-79	287.0	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,2TQV5@28211|Alphaproteobacteria,2K0KS@204457|Sphingomonadales	204457|Sphingomonadales	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19
CMS1_k127_1807565_3	685778.AORL01000021_gene372	2.054e-77	269.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,2TUFV@28211|Alphaproteobacteria,2K1QE@204457|Sphingomonadales	204457|Sphingomonadales	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
CMS1_k127_1807565_4	279238.Saro_1783	3.597e-72	252.0	COG3931@1|root,COG3931@2|Bacteria,1QI71@1224|Proteobacteria,2TVK6@28211|Alphaproteobacteria,2K3BC@204457|Sphingomonadales	204457|Sphingomonadales	E	N-formylglutamate amidohydrolase	-	-	3.5.1.68	ko:K01458	ko00340,ko00630,map00340,map00630	-	R00525	RC00165,RC00323	ko00000,ko00001,ko01000	-	-	-	FGase
CMS1_k127_1807565_0	194867.ALBQ01000018_gene2584	4.319e-319	983.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,2TRTQ@28211|Alphaproteobacteria,2K026@204457|Sphingomonadales	204457|Sphingomonadales	EG	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
CMS1_k127_1807565_6	1537715.JQFJ01000002_gene360	7.35e-27	115.0	2AM4Z@1|root,31BZ9@2|Bacteria,1NJ2Q@1224|Proteobacteria,2UM5S@28211|Alphaproteobacteria,2K6T2@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1807565_1	1545915.JROG01000003_gene1074	2.457e-98	334.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,2TT58@28211|Alphaproteobacteria,2K1P3@204457|Sphingomonadales	204457|Sphingomonadales	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	-	-	-	-	-	-	-	-	-	-	Carb_kinase,YjeF_N
CMS1_k127_1817412_3	1120705.FG95_00626	5.445e-92	306.0	COG2199@1|root,COG2199@2|Bacteria,1R49V@1224|Proteobacteria,2TTDC@28211|Alphaproteobacteria,2K4KD@204457|Sphingomonadales	204457|Sphingomonadales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
CMS1_k127_1817412_0	1207055.C100_03255	0.0	1077.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria,2K02H@204457|Sphingomonadales	204457|Sphingomonadales	V	Efflux pump membrane transporter	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
CMS1_k127_1817412_2	1234595.C725_1620	3.807e-120	396.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,2U2CU@28211|Alphaproteobacteria,4BQ7H@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K03585,ko:K18306	ko01501,ko01503,ko02024,map01501,map01503,map02024	M00644,M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,2.A.6.2.20,2.A.6.2.32,8.A.1,8.A.1.6	-	-	HlyD_D23
CMS1_k127_1817412_4	663610.JQKO01000025_gene250	1.529e-88	302.0	COG2207@1|root,COG2207@2|Bacteria,1N0FA@1224|Proteobacteria,2TW52@28211|Alphaproteobacteria,3ND0G@45404|Beijerinckiaceae	28211|Alphaproteobacteria	K	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_6,HTH_18
CMS1_k127_1817412_1	1122132.AQYH01000008_gene2343	2.662e-186	592.0	COG0277@1|root,COG0277@2|Bacteria,1MUPW@1224|Proteobacteria,2TUNK@28211|Alphaproteobacteria,4BCK6@82115|Rhizobiaceae	28211|Alphaproteobacteria	C	Berberine and berberine like	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
CMS1_k127_1817412_5	269799.Gmet_2217	1.306e-82	281.0	COG1028@1|root,COG1028@2|Bacteria,1MVQW@1224|Proteobacteria,42ZR2@68525|delta/epsilon subdivisions,2WV3H@28221|Deltaproteobacteria,43V3V@69541|Desulfuromonadales	28221|Deltaproteobacteria	IQ	KR domain	-	-	1.1.1.51	ko:K05296	ko00140,ko00984,ko01100,ko01120,map00140,map00984,map01100,map01120	-	R01836,R01838,R02352,R02353,R03406,R03407,R09956,R09957	RC00127,RC00144	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
CMS1_k127_1817412_6	1265313.HRUBRA_01847	1.235e-26	119.0	COG5517@1|root,COG5517@2|Bacteria,1N8U1@1224|Proteobacteria,1TH8Y@1236|Gammaproteobacteria,1JB7R@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	Q	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
CMS1_k127_1818142_4	693986.MOC_4537	1.159e-104	343.0	COG1902@1|root,COG1902@2|Bacteria,1MVIX@1224|Proteobacteria,2TT2F@28211|Alphaproteobacteria,1JS7Z@119045|Methylobacteriaceae	28211|Alphaproteobacteria	C	NADH flavin oxidoreductase NADH oxidase	-	-	-	ko:K10680	ko00633,ko01120,map00633,map01120	-	R08014,R08017,R08042	RC00250	ko00000,ko00001,ko01000	-	-	-	Oxidored_FMN
CMS1_k127_1818142_6	1550073.JROH01000001_gene587	1.79e-78	268.0	COG5590@1|root,COG5590@2|Bacteria,1MW25@1224|Proteobacteria,2U9ST@28211|Alphaproteobacteria,2K3VY@204457|Sphingomonadales	204457|Sphingomonadales	S	RpsU-divergently transcribed	-	-	-	ko:K18587	-	-	-	-	ko00000	-	-	-	COQ9
CMS1_k127_1818142_9	702113.PP1Y_AT12077	7.561e-19	89.0	COG1918@1|root,COG1918@2|Bacteria,1N7XK@1224|Proteobacteria,2UI27@28211|Alphaproteobacteria,2K6S7@204457|Sphingomonadales	204457|Sphingomonadales	P	Fe2 transport system protein A	feoA	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
CMS1_k127_1818142_0	1248760.ANFZ01000011_gene255	7.036e-285	885.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,2TQSU@28211|Alphaproteobacteria,2K0AQ@204457|Sphingomonadales	204457|Sphingomonadales	P	Ferrous iron transport protein B	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
CMS1_k127_1818142_8	13689.BV96_01155	8.242e-62	222.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,2U5BZ@28211|Alphaproteobacteria,2K464@204457|Sphingomonadales	204457|Sphingomonadales	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
CMS1_k127_1818142_5	401053.AciPR4_2920	4.506e-79	276.0	COG2199@1|root,COG3706@2|Bacteria,3Y6ZN@57723|Acidobacteria,2JKFD@204432|Acidobacteriia	204432|Acidobacteriia	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,MASE1
CMS1_k127_1818142_3	1331060.RLDS_15390	3.228e-123	414.0	COG0807@1|root,COG0807@2|Bacteria,1MWZR@1224|Proteobacteria,2TR82@28211|Alphaproteobacteria,2K0DD@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate	ribA	-	3.5.4.25	ko:K01497	ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024	M00125	R00425	RC00293,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydro2
CMS1_k127_1818142_2	1335760.ASTG01000017_gene3502	7.641e-132	425.0	COG0708@1|root,COG0708@2|Bacteria,1MVMC@1224|Proteobacteria,2TRWQ@28211|Alphaproteobacteria,2K09T@204457|Sphingomonadales	204457|Sphingomonadales	L	exodeoxyribonuclease III	-	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
CMS1_k127_1818142_7	1522072.IL54_3627	7.062e-77	262.0	COG2834@1|root,COG2834@2|Bacteria,1RA1S@1224|Proteobacteria,2U58W@28211|Alphaproteobacteria,2K43J@204457|Sphingomonadales	204457|Sphingomonadales	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	lolA	-	-	-	-	-	-	-	-	-	-	-	LolA
CMS1_k127_1818142_1	1123270.ATUR01000004_gene1749	1.093e-230	717.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,2TR48@28211|Alphaproteobacteria,2K02P@204457|Sphingomonadales	204457|Sphingomonadales	D	DNA segregation ATPase FtsK SpoIIIE	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
CMS1_k127_1820579_7	565045.NOR51B_2492	1.014e-07	55.0	COG4638@1|root,COG4638@2|Bacteria,1NS0X@1224|Proteobacteria	1224|Proteobacteria	P	Rieske 2Fe2S	-	-	-	-	-	-	-	-	-	-	-	-	Rieske,Ring_hydroxyl_A
CMS1_k127_1820579_6	1397666.RS24_01578	1.667e-40	157.0	COG5517@1|root,COG5517@2|Bacteria,1N35U@1224|Proteobacteria,2UCQY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
CMS1_k127_1820579_0	1331060.RLDS_04895	2.053e-308	967.0	COG4774@1|root,COG4774@2|Bacteria,1NMCN@1224|Proteobacteria,2TVPT@28211|Alphaproteobacteria,2K2IS@204457|Sphingomonadales	204457|Sphingomonadales	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
CMS1_k127_1820579_4	1219045.BV98_000156	1.834e-128	415.0	COG1409@1|root,COG1409@2|Bacteria,1MW6B@1224|Proteobacteria,2U1GX@28211|Alphaproteobacteria,2K28P@204457|Sphingomonadales	204457|Sphingomonadales	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
CMS1_k127_1820579_3	1207055.C100_09375	6.055e-129	419.0	COG1597@1|root,COG1597@2|Bacteria,1MY37@1224|Proteobacteria,2TT5I@28211|Alphaproteobacteria,2K1UU@204457|Sphingomonadales	204457|Sphingomonadales	I	Diacylglycerol kinase	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
CMS1_k127_1820579_8	932213.SPM24T3_02953	3.017e-05	46.0	COG0433@1|root,COG0433@2|Bacteria,1QRTM@1224|Proteobacteria,1SXHJ@1236|Gammaproteobacteria,40591@613|Serratia	1236|Gammaproteobacteria	S	Domain of unknown function DUF87	-	-	-	-	-	-	-	-	-	-	-	-	DUF87
CMS1_k127_1820579_1	1096930.L284_11035	2.901e-242	756.0	COG4992@1|root,COG4992@2|Bacteria,1R6U9@1224|Proteobacteria,2TUDK@28211|Alphaproteobacteria,2K8IE@204457|Sphingomonadales	204457|Sphingomonadales	E	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
CMS1_k127_1820579_5	1096930.L284_11030	1.529e-121	408.0	2C1UQ@1|root,33VUD@2|Bacteria,1RM45@1224|Proteobacteria,2UBKR@28211|Alphaproteobacteria,2K9TG@204457|Sphingomonadales	204457|Sphingomonadales	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS1_k127_1820579_2	1096930.L284_11025	2.446e-137	446.0	COG0382@1|root,COG0382@2|Bacteria,1QBNE@1224|Proteobacteria,2U10K@28211|Alphaproteobacteria,2K9MP@204457|Sphingomonadales	204457|Sphingomonadales	H	UbiA prenyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	UbiA
CMS1_k127_1829056_6	1545915.JROG01000003_gene713	7.711e-16	79.0	COG2124@1|root,COG2124@2|Bacteria,1MV75@1224|Proteobacteria,2TSV7@28211|Alphaproteobacteria,2K088@204457|Sphingomonadales	204457|Sphingomonadales	Q	Cytochrome p450	-	-	-	-	-	-	-	-	-	-	-	-	p450
CMS1_k127_1829056_5	1537715.JQFJ01000002_gene1231	3.145e-20	99.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	atl	-	3.2.1.96,3.5.1.28	ko:K13714	-	-	-	-	ko00000,ko01000	-	GH73	-	Glucosaminidase,Gram_pos_anchor,SH3_8,SPOR,YSIRK_signal
CMS1_k127_1829056_0	1120792.JAFV01000001_gene403	7.634e-108	360.0	COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,2TSWD@28211|Alphaproteobacteria,36ZUT@31993|Methylocystaceae	28211|Alphaproteobacteria	I	Fatty acid desaturase	-	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
CMS1_k127_1829056_4	1174684.EBMC1_01035	1.732e-21	100.0	COG3149@1|root,COG3149@2|Bacteria,1NGFT@1224|Proteobacteria,2UM4J@28211|Alphaproteobacteria,2K76J@204457|Sphingomonadales	204457|Sphingomonadales	U	Type II secretion system (T2SS), protein M	-	-	-	ko:K02462	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSM
CMS1_k127_1829056_3	1346791.M529_05830	7.606e-38	156.0	COG3297@1|root,COG3297@2|Bacteria,1N0FQ@1224|Proteobacteria,2VG98@28211|Alphaproteobacteria,2KE27@204457|Sphingomonadales	204457|Sphingomonadales	U	General secretion pathway protein L	-	-	-	-	-	-	-	-	-	-	-	-	GspL_C,T2SSL
CMS1_k127_1829056_2	1545915.JROG01000007_gene3091	4.329e-59	208.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,2U8VA@28211|Alphaproteobacteria,2K4TG@204457|Sphingomonadales	204457|Sphingomonadales	NU	general secretion pathway protein G	gspG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
CMS1_k127_1829056_1	1123270.ATUR01000003_gene806	8.977e-93	308.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,2TV76@28211|Alphaproteobacteria,2K0ZH@204457|Sphingomonadales	204457|Sphingomonadales	U	General secretion pathway protein F	gspF	-	-	ko:K02455	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
CMS1_k127_1829442_0	1123270.ATUR01000002_gene2701	1.309e-188	607.0	COG2911@1|root,COG2911@2|Bacteria,1R4BU@1224|Proteobacteria,2TSKR@28211|Alphaproteobacteria,2K0MI@204457|Sphingomonadales	204457|Sphingomonadales	S	Dicarboxylate transport	-	-	-	-	-	-	-	-	-	-	-	-	DctA-YdbH
CMS1_k127_1829442_3	1248760.ANFZ01000006_gene2640	1.803e-14	78.0	2AKQN@1|root,31BHD@2|Bacteria,1Q7C6@1224|Proteobacteria,2UJNT@28211|Alphaproteobacteria,2K6TW@204457|Sphingomonadales	204457|Sphingomonadales	S	YnbE-like lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_19
CMS1_k127_1829442_2	1502850.FG91_02430	4.551e-48	175.0	COG3784@1|root,COG3784@2|Bacteria,1Q09W@1224|Proteobacteria,2UCIH@28211|Alphaproteobacteria,2K5RZ@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	ko:K09978	-	-	-	-	ko00000	-	-	-	DUF1318
CMS1_k127_1829442_1	911045.PSE_2084	1.211e-104	350.0	COG1024@1|root,COG1024@2|Bacteria,1NDT7@1224|Proteobacteria,2U2R9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS1_k127_1833177_3	1537715.JQFJ01000002_gene1782	7.279e-67	229.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,2TTB9@28211|Alphaproteobacteria,2K212@204457|Sphingomonadales	204457|Sphingomonadales	I	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
CMS1_k127_1833177_5	1545915.JROG01000007_gene3052	4.264e-20	93.0	29188@1|root,2ZNVC@2|Bacteria,1NM5D@1224|Proteobacteria,2UMZG@28211|Alphaproteobacteria,2K7SH@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1833177_0	1502850.FG91_03764	1.549e-264	828.0	COG0624@1|root,COG0624@2|Bacteria,1MW20@1224|Proteobacteria,2TQY4@28211|Alphaproteobacteria,2K117@204457|Sphingomonadales	204457|Sphingomonadales	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
CMS1_k127_1833177_1	1248760.ANFZ01000009_gene902	1.08e-135	437.0	COG0596@1|root,COG0596@2|Bacteria,1MUSF@1224|Proteobacteria,2TSK5@28211|Alphaproteobacteria,2JZV9@204457|Sphingomonadales	204457|Sphingomonadales	S	Alpha/beta hydrolase family	-	-	3.8.1.5	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
CMS1_k127_1833177_4	1123270.ATUR01000004_gene1646	3.69e-45	177.0	COG3637@1|root,COG3637@2|Bacteria,1NJWW@1224|Proteobacteria,2UD8G@28211|Alphaproteobacteria,2K4HB@204457|Sphingomonadales	204457|Sphingomonadales	M	Outer membrane protein beta-barrel domain	-	-	-	ko:K16079	-	-	-	-	ko00000,ko02000	1.B.4.2.1	-	-	OMP_b-brl
CMS1_k127_1833177_2	452662.SJA_C1-08850	6.671e-67	233.0	COG2135@1|root,COG2135@2|Bacteria,1PZ3Z@1224|Proteobacteria,2TTEE@28211|Alphaproteobacteria,2K462@204457|Sphingomonadales	204457|Sphingomonadales	S	SOS response associated peptidase (SRAP)	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
CMS1_k127_1833177_6	1265313.HRUBRA_02128	2.655e-09	60.0	COG2211@1|root,COG2211@2|Bacteria,1MVUM@1224|Proteobacteria,1RP5J@1236|Gammaproteobacteria,1JAKV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	COG2211 Na melibiose symporter and related transporters	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
CMS1_k127_1842398_0	1248916.ANFY01000006_gene1960	1.395e-194	628.0	COG0758@1|root,COG0758@2|Bacteria,1R9P1@1224|Proteobacteria,2U30Q@28211|Alphaproteobacteria,2K3JF@204457|Sphingomonadales	204457|Sphingomonadales	LU	DNA mediated transformation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1842398_2	1123267.JONN01000002_gene283	5.258e-43	179.0	COG5640@1|root,COG5640@2|Bacteria,1NFNT@1224|Proteobacteria,2U9RV@28211|Alphaproteobacteria,2K755@204457|Sphingomonadales	204457|Sphingomonadales	O	Trypsin-like serine protease	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin
CMS1_k127_1842398_1	1123267.JONN01000002_gene285	6.904e-134	443.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1N7YB@1224|Proteobacteria,2V7CZ@28211|Alphaproteobacteria,2K2SU@204457|Sphingomonadales	204457|Sphingomonadales	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
CMS1_k127_1849793_1	1397666.RS24_01028	6.998e-149	477.0	COG1215@1|root,COG1215@2|Bacteria,1MWH9@1224|Proteobacteria,2TUGH@28211|Alphaproteobacteria,4BRRW@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	M	COG0463 Glycosyltransferases involved in cell wall biogenesis	gpgS	-	2.4.1.266	ko:K13693	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	-
CMS1_k127_1849793_0	1026882.MAMP_02777	5.053e-203	648.0	COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,1RMXP@1236|Gammaproteobacteria,45ZX1@72273|Thiotrichales	72273|Thiotrichales	G	Alpha amylase, catalytic domain	-	-	2.4.1.7	ko:K00690	ko00500,map00500	-	R00803	RC00028	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase
CMS1_k127_1849793_2	987059.RBXJA2T_03838	1.293e-105	357.0	COG2379@1|root,COG2379@2|Bacteria,1MVIK@1224|Proteobacteria,2VHXK@28216|Betaproteobacteria,1KK4W@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	MOFRL family	ttuD	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
CMS1_k127_1849793_3	1479239.JQMU01000001_gene827	4.803e-84	296.0	COG4252@1|root,COG5001@1|root,COG4252@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TW2U@28211|Alphaproteobacteria,2KE9I@204457|Sphingomonadales	204457|Sphingomonadales	T	CHASE2	-	-	-	-	-	-	-	-	-	-	-	-	CHASE2,EAL
CMS1_k127_1856100_4	1545915.JROG01000008_gene3356	4.481e-117	383.0	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,2TU0C@28211|Alphaproteobacteria,2K329@204457|Sphingomonadales	204457|Sphingomonadales	P	Sodium:sulfate symporter transmembrane region	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
CMS1_k127_1856100_0	1248760.ANFZ01000011_gene273	9.616e-225	702.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,2TW14@28211|Alphaproteobacteria,2K1W3@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the formation of methanethiol and 2-ocobutanoate from L-methionine	-	-	4.4.1.11	ko:K01761	ko00270,ko00450,map00270,map00450	-	R00654,R04770	RC00196,RC00348,RC01209,RC01210	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
CMS1_k127_1856100_9	1522072.IL54_1836	8.754e-55	195.0	COG3439@1|root,COG3439@2|Bacteria,1RH9Z@1224|Proteobacteria,2UAEV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
CMS1_k127_1856100_13	983920.Y88_1064	3.896e-27	117.0	COG5455@1|root,COG5455@2|Bacteria	2|Bacteria	D	response to cobalt ion	cigR	-	-	-	-	-	-	-	-	-	-	-	RcnB
CMS1_k127_1856100_8	1144305.PMI02_04290	3.986e-55	198.0	COG0782@1|root,COG0782@2|Bacteria,1RHU5@1224|Proteobacteria,2UHKS@28211|Alphaproteobacteria,2KDS7@204457|Sphingomonadales	204457|Sphingomonadales	K	Transcription elongation factor, GreA/GreB, C-term	-	-	-	-	-	-	-	-	-	-	-	-	GreA_GreB
CMS1_k127_1856100_12	1096930.L284_08370	1.908e-27	118.0	2ANCV@1|root,31DBE@2|Bacteria,1P1TY@1224|Proteobacteria,2UUG9@28211|Alphaproteobacteria,2K6Y0@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1856100_7	685778.AORL01000009_gene3223	7.247e-71	247.0	COG0560@1|root,COG0560@2|Bacteria,1P4TB@1224|Proteobacteria,2UHTZ@28211|Alphaproteobacteria,2K3BN@204457|Sphingomonadales	204457|Sphingomonadales	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
CMS1_k127_1856100_1	1123269.NX02_24415	1.585e-153	493.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,2TSGS@28211|Alphaproteobacteria,2K10W@204457|Sphingomonadales	204457|Sphingomonadales	Q	ABC-type transport system involved in resistance to organic solvents, permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
CMS1_k127_1856100_2	1090318.ATTI01000001_gene753	5.546e-127	421.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,2TR2I@28211|Alphaproteobacteria,2K11G@204457|Sphingomonadales	204457|Sphingomonadales	Q	ABC-type transport system involved in resistance to organic solvents, ATPase component	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
CMS1_k127_1856100_5	1123269.NX02_24425	8.558e-117	383.0	COG1463@1|root,COG1463@2|Bacteria,1MU4B@1224|Proteobacteria,2U1JN@28211|Alphaproteobacteria,2K12E@204457|Sphingomonadales	204457|Sphingomonadales	Q	ABC-type transport system involved in resistance to organic solvents, periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
CMS1_k127_1856100_11	685035.ADAE01000018_gene1170	1.26e-39	155.0	COG3218@1|root,COG3218@2|Bacteria,1RKTW@1224|Proteobacteria,2UAXY@28211|Alphaproteobacteria,2K5KR@204457|Sphingomonadales	204457|Sphingomonadales	S	transport system auxiliary component	linN	-	-	ko:K18480	-	M00669	-	-	ko00000,ko00002,ko02000	3.A.1.27.1	-	-	ABC_trans_aux
CMS1_k127_1856100_6	1219035.NT2_04_00980	4.891e-114	378.0	COG1565@1|root,COG1565@2|Bacteria,1N3CJ@1224|Proteobacteria,2TRHW@28211|Alphaproteobacteria,2K21E@204457|Sphingomonadales	204457|Sphingomonadales	M	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	ko:K18164	ko04714,map04714	-	-	-	ko00000,ko00001,ko03029	-	-	-	Methyltransf_28
CMS1_k127_1856100_3	1030157.AFMP01000050_gene15	6.628e-121	391.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,2TTNS@28211|Alphaproteobacteria,2K1JZ@204457|Sphingomonadales	204457|Sphingomonadales	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
CMS1_k127_1857761_6	1545915.JROG01000001_gene124	4.933e-68	246.0	COG1073@1|root,COG1073@2|Bacteria,1R61B@1224|Proteobacteria,2U45E@28211|Alphaproteobacteria,2K10H@204457|Sphingomonadales	204457|Sphingomonadales	S	TIGRFAM Hydrolase, ortholog 1, exosortase system type 1 associated	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Hydrolase_4
CMS1_k127_1857761_7	1545915.JROG01000001_gene125	1.85e-55	202.0	COG2267@1|root,COG2267@2|Bacteria,1RJMW@1224|Proteobacteria,2UB7N@28211|Alphaproteobacteria,2K5KA@204457|Sphingomonadales	204457|Sphingomonadales	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1857761_9	1545915.JROG01000001_gene126	4.484e-31	123.0	COG0236@1|root,COG0236@2|Bacteria,1N83X@1224|Proteobacteria,2UFBF@28211|Alphaproteobacteria,2K6WR@204457|Sphingomonadales	204457|Sphingomonadales	IQ	acyl carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
CMS1_k127_1857761_5	1248760.ANFZ01000006_gene2553	2.21e-102	346.0	COG5653@1|root,COG5653@2|Bacteria,1RDJC@1224|Proteobacteria,2U32H@28211|Alphaproteobacteria,2K270@204457|Sphingomonadales	204457|Sphingomonadales	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
CMS1_k127_1857761_0	1123270.ATUR01000003_gene844	3.182e-199	633.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TRP2@28211|Alphaproteobacteria,2K0DK@204457|Sphingomonadales	204457|Sphingomonadales	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
CMS1_k127_1857761_2	1545915.JROG01000001_gene129	4.401e-181	574.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,2TUK2@28211|Alphaproteobacteria,2K0RW@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the Orn Lys Arg decarboxylase class-II family	-	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
CMS1_k127_1857761_3	1207055.C100_08695	3.972e-105	346.0	COG1596@1|root,COG1596@2|Bacteria,1RFBH@1224|Proteobacteria,2U835@28211|Alphaproteobacteria,2K15P@204457|Sphingomonadales	204457|Sphingomonadales	M	polysaccharide export	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
CMS1_k127_1857761_1	1123270.ATUR01000003_gene841	4.771e-186	595.0	COG3206@1|root,COG3206@2|Bacteria,1MVBX@1224|Proteobacteria,2U1E2@28211|Alphaproteobacteria,2K08I@204457|Sphingomonadales	204457|Sphingomonadales	M	Chain-length determining protein	-	-	-	-	-	-	-	-	-	-	-	-	GNVR,Wzz
CMS1_k127_1857761_4	1123270.ATUR01000003_gene840	2.073e-104	347.0	COG0489@1|root,COG0489@2|Bacteria,1PDUC@1224|Proteobacteria,2U2MQ@28211|Alphaproteobacteria,2K065@204457|Sphingomonadales	204457|Sphingomonadales	D	involved in chromosome partitioning	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA,ParA
CMS1_k127_1857761_8	1248760.ANFZ01000006_gene2786	3.093e-44	165.0	COG5338@1|root,COG5338@2|Bacteria,1R7QB@1224|Proteobacteria,2TSCP@28211|Alphaproteobacteria,2K2HY@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1878108_0	392499.Swit_1830	3.563e-212	667.0	COG1053@1|root,COG1053@2|Bacteria,1MURY@1224|Proteobacteria,2TSRQ@28211|Alphaproteobacteria,2K1EU@204457|Sphingomonadales	204457|Sphingomonadales	C	fumarate reductase	-	-	1.3.99.4	ko:K05898	ko00984,ko01100,ko01120,map00984,map01100,map01120	-	R09884	RC00991	ko00000,ko00001,ko01000	-	-	-	FAD_binding_2
CMS1_k127_1878108_1	392499.Swit_1829	1.344e-181	577.0	COG4638@1|root,COG4638@2|Bacteria,1MWU3@1224|Proteobacteria,2UPZD@28211|Alphaproteobacteria,2K2AI@204457|Sphingomonadales	204457|Sphingomonadales	P	Rieske [2Fe-2S] domain	kshA	-	1.14.13.142	ko:K15982	ko00984,ko01100,ko01120,map00984,map01100,map01120	-	R09860	RC02691	ko00000,ko00001,ko01000	-	-	-	Rieske
CMS1_k127_1878108_2	392499.Swit_1828	3.827e-179	568.0	COG1960@1|root,COG1960@2|Bacteria,1MXMQ@1224|Proteobacteria,2TTF6@28211|Alphaproteobacteria,2K97F@204457|Sphingomonadales	204457|Sphingomonadales	I	PFAM Acyl-CoA dehydrogenase, type 2, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_2
CMS1_k127_1878108_3	392499.Swit_1827	2.005e-113	376.0	COG2267@1|root,COG2267@2|Bacteria,1MW9H@1224|Proteobacteria,2U1YC@28211|Alphaproteobacteria,2K03U@204457|Sphingomonadales	204457|Sphingomonadales	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
CMS1_k127_1878108_4	392499.Swit_1826	3.448e-107	355.0	COG0346@1|root,COG0346@2|Bacteria,1P5FR@1224|Proteobacteria,2TVCC@28211|Alphaproteobacteria,2K36X@204457|Sphingomonadales	204457|Sphingomonadales	E	Glyoxalase bleomycin resistance protein dioxygenase	-	-	1.13.11.25	ko:K16049	ko00984,ko01100,ko01120,ko01220,map00984,map01100,map01120,map01220	-	R04597	RC01610	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
CMS1_k127_1878108_5	392499.Swit_1825	1.204e-70	244.0	COG1309@1|root,COG1309@2|Bacteria,1R8KS@1224|Proteobacteria,2TSYV@28211|Alphaproteobacteria,2K865@204457|Sphingomonadales	204457|Sphingomonadales	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS1_k127_194426_1	1144307.PMI04_02120	4.293e-67	239.0	COG0457@1|root,COG0457@2|Bacteria,1QUU4@1224|Proteobacteria,2TW7Q@28211|Alphaproteobacteria,2KECR@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF4071)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4071
CMS1_k127_194426_0	633149.Bresu_2076	3.387e-98	340.0	COG0457@1|root,COG0457@2|Bacteria,1N06S@1224|Proteobacteria,2TQVV@28211|Alphaproteobacteria,2KGCY@204458|Caulobacterales	204458|Caulobacterales	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1863
CMS1_k127_1954566_1	383381.EH30_15720	2.054e-176	565.0	COG4774@1|root,COG4774@2|Bacteria,1NMCN@1224|Proteobacteria,2TVPT@28211|Alphaproteobacteria,2K2IS@204457|Sphingomonadales	204457|Sphingomonadales	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
CMS1_k127_1954566_0	383381.EH30_15720	1e-322	1007.0	COG4774@1|root,COG4774@2|Bacteria,1NMCN@1224|Proteobacteria,2TVPT@28211|Alphaproteobacteria,2K2IS@204457|Sphingomonadales	204457|Sphingomonadales	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
CMS1_k127_1954566_3	392499.Swit_2259	4.43e-75	259.0	COG1028@1|root,COG1028@2|Bacteria,1MUPX@1224|Proteobacteria,2U471@28211|Alphaproteobacteria,2K3WA@204457|Sphingomonadales	204457|Sphingomonadales	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.51	ko:K05296	ko00140,ko00984,ko01100,ko01120,map00140,map00984,map01100,map01120	-	R01836,R01838,R02352,R02353,R03406,R03407,R09956,R09957	RC00127,RC00144	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
CMS1_k127_1954566_4	247634.GPB2148_2016	5.715e-31	126.0	COG4308@1|root,COG4308@2|Bacteria,1NBHZ@1224|Proteobacteria,1SD3C@1236|Gammaproteobacteria,1JB1K@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG4308 Limonene-1,2-epoxide hydrolase	-	-	3.3.2.8	ko:K10533	ko00903,map00903	-	R05784,R09387	RC01473,RC02519	ko00000,ko00001,ko01000	-	-	-	LEH
CMS1_k127_1954566_2	1220535.IMCC14465_09450	2.826e-137	441.0	COG2130@1|root,COG2130@2|Bacteria,1MUC2@1224|Proteobacteria,2TQYM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	NADP-dependent oxidoreductase	-	-	-	ko:K07119	-	-	-	-	ko00000	-	-	-	ADH_N_2,ADH_zinc_N
CMS1_k127_1985233_1	1545915.JROG01000007_gene3230	1.665e-75	257.0	COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,2TSQN@28211|Alphaproteobacteria,2KCC8@204457|Sphingomonadales	204457|Sphingomonadales	C	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
CMS1_k127_1985233_2	1248760.ANFZ01000009_gene842	7.472e-75	259.0	COG0730@1|root,COG0730@2|Bacteria,1RD5A@1224|Proteobacteria,2U7QA@28211|Alphaproteobacteria,2K4T4@204457|Sphingomonadales	204457|Sphingomonadales	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
CMS1_k127_1985233_0	1248760.ANFZ01000009_gene841	0.0	1415.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,2TTBF@28211|Alphaproteobacteria,2K1MX@204457|Sphingomonadales	204457|Sphingomonadales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
CMS1_k127_2015516_0	1545915.JROG01000007_gene3061	0.0	1204.0	COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,2TR7V@28211|Alphaproteobacteria,2K0I6@204457|Sphingomonadales	204457|Sphingomonadales	L	helicase	lhr	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
CMS1_k127_2015516_1	1280941.HY2_14585	6.168e-142	458.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,2TQUY@28211|Alphaproteobacteria,440PV@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS1_k127_2015516_2	627192.SLG_01340	2.127e-116	385.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,2TVGG@28211|Alphaproteobacteria,2K0BX@204457|Sphingomonadales	204457|Sphingomonadales	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
CMS1_k127_2015516_3	383381.EH30_11275	2.115e-27	112.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,2TRGU@28211|Alphaproteobacteria,2K07K@204457|Sphingomonadales	204457|Sphingomonadales	BQ	histone deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
CMS1_k127_2015935_2	314225.ELI_07325	1.223e-107	358.0	COG0604@1|root,COG0604@2|Bacteria,1QUNT@1224|Proteobacteria,2TW28@28211|Alphaproteobacteria,2K36M@204457|Sphingomonadales	204457|Sphingomonadales	C	Protein of unknown function (DUF2855)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2855
CMS1_k127_2015935_0	1248760.ANFZ01000008_gene1608	2.6e-207	661.0	COG0664@1|root,COG1752@1|root,COG0664@2|Bacteria,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,2TVQR@28211|Alphaproteobacteria,2K876@204457|Sphingomonadales	204457|Sphingomonadales	T	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin,cNMP_binding
CMS1_k127_2015935_8	291985.CCSI01000007_gene571	1.879e-16	85.0	2ATYG@1|root,31JI4@2|Bacteria,1N46N@1224|Proteobacteria,2UCQE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2015935_4	555793.WSK_3164	2.787e-53	192.0	COG5323@1|root,COG5323@2|Bacteria,1MW8S@1224|Proteobacteria,2TREI@28211|Alphaproteobacteria,2K2BG@204457|Sphingomonadales	204457|Sphingomonadales	S	Terminase RNaseH-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_6,Terminase_6C
CMS1_k127_2015935_6	1123270.ATUR01000002_gene2169	4.981e-29	121.0	28JTG@1|root,2Z9IR@2|Bacteria,1R0GC@1224|Proteobacteria,2TURR@28211|Alphaproteobacteria,2K59T@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF2793)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2793
CMS1_k127_2015935_1	317655.Sala_1988	4.456e-156	499.0	COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1N6EM@1224|Proteobacteria,2U17R@28211|Alphaproteobacteria,2K18P@204457|Sphingomonadales	204457|Sphingomonadales	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,OMP_b-brl,OmpA
CMS1_k127_2015935_3	1449076.JOOE01000001_gene2446	1.338e-100	334.0	COG0047@1|root,COG0047@2|Bacteria,1MU4Y@1224|Proteobacteria,2TS67@28211|Alphaproteobacteria,2K0NC@204457|Sphingomonadales	204457|Sphingomonadales	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
CMS1_k127_2015935_5	1123269.NX02_14560	3.833e-29	118.0	COG1828@1|root,COG1828@2|Bacteria,1N83G@1224|Proteobacteria,2UF7S@28211|Alphaproteobacteria,2K5YV@204457|Sphingomonadales	204457|Sphingomonadales	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	PurS
CMS1_k127_2015935_7	1090320.KB900605_gene2031	2.376e-26	108.0	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,2TR8D@28211|Alphaproteobacteria,2K0D0@204457|Sphingomonadales	204457|Sphingomonadales	F	Belongs to the SAICAR synthetase family	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
CMS1_k127_2028790_1	383381.EH30_02140	8.883e-132	433.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,2VCDT@28211|Alphaproteobacteria,2K77X@204457|Sphingomonadales	204457|Sphingomonadales	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
CMS1_k127_2028790_0	517722.AEUE01000001_gene2681	1.117e-245	766.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2TS8E@28211|Alphaproteobacteria,2K0RP@204457|Sphingomonadales	204457|Sphingomonadales	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
CMS1_k127_2037050_0	1248760.ANFZ01000009_gene1446	0.0	1099.0	COG1770@1|root,COG1770@2|Bacteria,1MUED@1224|Proteobacteria,2TTR0@28211|Alphaproteobacteria,2K19E@204457|Sphingomonadales	204457|Sphingomonadales	E	peptidase S9	ptrB	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
CMS1_k127_2037050_2	1090320.KB900605_gene1153	6.229e-54	194.0	COG0824@1|root,COG0824@2|Bacteria,1N06V@1224|Proteobacteria,2UCAQ@28211|Alphaproteobacteria,2K5A4@204457|Sphingomonadales	204457|Sphingomonadales	S	thioesterase	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	Acyl-ACP_TE
CMS1_k127_2037050_1	1123270.ATUR01000004_gene1802	7.576e-80	277.0	291EX@1|root,2ZP1S@2|Bacteria,1RF3T@1224|Proteobacteria,2U83Z@28211|Alphaproteobacteria,2K4S8@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Mitofilin
CMS1_k127_2037050_3	314225.ELI_09150	3.302e-21	98.0	COG1587@1|root,COG1587@2|Bacteria,1NMTP@1224|Proteobacteria,2UMED@28211|Alphaproteobacteria,2K52Q@204457|Sphingomonadales	204457|Sphingomonadales	H	Uroporphyrinogen-III synthase	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
CMS1_k127_2046156_5	555793.WSK_2268	6.954e-88	308.0	COG0627@1|root,COG0627@2|Bacteria,1MUID@1224|Proteobacteria,2TQSM@28211|Alphaproteobacteria,2K143@204457|Sphingomonadales	204457|Sphingomonadales	S	Serine hydrolase involved in the detoxification of formaldehyde	fghA	-	3.1.2.12	ko:K01070	ko00680,ko01120,ko01200,map00680,map01120,map01200	-	R00527	RC00167,RC00320	ko00000,ko00001,ko01000	-	CE1	-	Esterase
CMS1_k127_2046156_1	745310.G432_12585	2.691e-227	706.0	COG1062@1|root,COG1062@2|Bacteria,1MUK4@1224|Proteobacteria,2TT67@28211|Alphaproteobacteria,2K04T@204457|Sphingomonadales	204457|Sphingomonadales	C	Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_2046156_3	1522072.IL54_1610	1.049e-126	411.0	COG0788@1|root,COG0788@2|Bacteria,1MVCF@1224|Proteobacteria,2TR4V@28211|Alphaproteobacteria,2K0F7@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)	purU	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	ACT,ACT_6,Formyl_trans_N
CMS1_k127_2046156_2	1537715.JQFJ01000002_gene2458	1.207e-215	674.0	COG1960@1|root,COG1960@2|Bacteria,1MVAH@1224|Proteobacteria,2TR02@28211|Alphaproteobacteria,2K124@204457|Sphingomonadales	204457|Sphingomonadales	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS1_k127_2046156_4	279238.Saro_3796	1.546e-93	316.0	COG3777@1|root,COG3777@2|Bacteria,1P96N@1224|Proteobacteria,2TV0U@28211|Alphaproteobacteria,2K2J9@204457|Sphingomonadales	204457|Sphingomonadales	S	N-terminal half of MaoC dehydratase	-	-	4.2.1.153	ko:K09709	ko00720,ko01120,ko01200,map00720,map01120,map01200	M00376	R09282	RC02479	ko00000,ko00001,ko00002,ko01000	-	-	-	MaoC_dehydrat_N,MaoC_dehydratas
CMS1_k127_2046156_0	158500.BV97_03458	0.0	1240.0	COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,2TQJ7@28211|Alphaproteobacteria,2K0B7@204457|Sphingomonadales	204457|Sphingomonadales	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
CMS1_k127_205530_12	1044.EH31_05625	1.134e-16	80.0	COG0484@1|root,COG0484@2|Bacteria,1RASJ@1224|Proteobacteria,2U5FR@28211|Alphaproteobacteria,2K3W9@204457|Sphingomonadales	204457|Sphingomonadales	O	molecular chaperone	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
CMS1_k127_205530_11	1150626.PHAMO_10077	2.394e-19	91.0	2DI18@1|root,301P8@2|Bacteria,1PTHJ@1224|Proteobacteria,2V5D3@28211|Alphaproteobacteria,2JYAW@204441|Rhodospirillales	204441|Rhodospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_205530_5	1346791.M529_07560	2.461e-114	372.0	COG3023@1|root,COG3023@2|Bacteria,1RDHU@1224|Proteobacteria,2TSW3@28211|Alphaproteobacteria,2K0W6@204457|Sphingomonadales	204457|Sphingomonadales	V	N-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01447	-	-	R04112	RC00064,RC00141	ko00000,ko01000	-	-	-	Amidase_2
CMS1_k127_205530_9	1114964.L485_11215	1.922e-72	250.0	COG5385@1|root,COG5385@2|Bacteria,1MVEY@1224|Proteobacteria,2TSE6@28211|Alphaproteobacteria,2K0H0@204457|Sphingomonadales	204457|Sphingomonadales	S	Histidine phosphotransferase C-terminal domain	-	-	-	ko:K13588	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001	-	-	-	HPTransfase
CMS1_k127_205530_10	1248760.ANFZ01000018_gene752	1.682e-34	136.0	COG1310@1|root,COG1310@2|Bacteria,1NC23@1224|Proteobacteria,2UGM4@28211|Alphaproteobacteria,2K62I@204457|Sphingomonadales	204457|Sphingomonadales	L	metal-dependent protease of the PAD1 JAB1 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Prok-JAB
CMS1_k127_205530_4	1545915.JROG01000004_gene2300	1.091e-118	393.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,2TSBK@28211|Alphaproteobacteria,2K1VU@204457|Sphingomonadales	204457|Sphingomonadales	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
CMS1_k127_205530_3	317655.Sala_1743	9.581e-150	480.0	COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,2TR9Q@28211|Alphaproteobacteria,2K1G6@204457|Sphingomonadales	204457|Sphingomonadales	K	RNA polymerase sigma	rpoH	-	-	ko:K03089	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r4
CMS1_k127_205530_7	1123270.ATUR01000002_gene2673	1.403e-98	325.0	COG0744@1|root,COG0744@2|Bacteria,1RDAQ@1224|Proteobacteria,2U0NP@28211|Alphaproteobacteria,2K0ZN@204457|Sphingomonadales	204457|Sphingomonadales	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
CMS1_k127_205530_0	1207055.C100_21315	2.848e-246	764.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,2TS3R@28211|Alphaproteobacteria,2JZWY@204457|Sphingomonadales	204457|Sphingomonadales	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
CMS1_k127_205530_6	1123270.ATUR01000002_gene2670	7.052e-110	359.0	COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,2TR5M@28211|Alphaproteobacteria,2JZX6@204457|Sphingomonadales	204457|Sphingomonadales	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
CMS1_k127_205530_8	517722.AEUE01000008_gene213	5.172e-91	303.0	COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,2TR5M@28211|Alphaproteobacteria,2JZX6@204457|Sphingomonadales	204457|Sphingomonadales	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	-	-	-	-	-	-	-	-	-	-	-	-	CLP_protease
CMS1_k127_205530_2	1123270.ATUR01000002_gene2669	3.602e-202	642.0	COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,2TS8W@28211|Alphaproteobacteria,2K02U@204457|Sphingomonadales	204457|Sphingomonadales	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
CMS1_k127_205530_13	1120963.KB894491_gene1107	1.771e-06	49.0	2DE24@1|root,2ZK69@2|Bacteria,1P9N5@1224|Proteobacteria,1SU0Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_205530_1	1379701.JPJC01000012_gene153	7.896e-228	711.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,2TRHX@28211|Alphaproteobacteria,2K04H@204457|Sphingomonadales	204457|Sphingomonadales	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
CMS1_k127_2069149_0	1545915.JROG01000004_gene1719	1.682e-218	706.0	COG4625@1|root,COG5640@1|root,COG4625@2|Bacteria,COG5640@2|Bacteria,1NS3H@1224|Proteobacteria,2U1SB@28211|Alphaproteobacteria,2K2MI@204457|Sphingomonadales	204457|Sphingomonadales	E	Trypsin-like serine protease	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,PATR,Peptidase_S8,Trypsin
CMS1_k127_2069149_4	1248760.ANFZ01000002_gene3031	6.381e-65	226.0	COG0783@1|root,COG0783@2|Bacteria,1RAC5@1224|Proteobacteria,2U5Q5@28211|Alphaproteobacteria,2K3YI@204457|Sphingomonadales	204457|Sphingomonadales	P	Belongs to the Dps family	-	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
CMS1_k127_2069149_7	1248760.ANFZ01000002_gene3030	1.862e-47	181.0	COG2119@1|root,COG2119@2|Bacteria,1NSQU@1224|Proteobacteria,2UHM7@28211|Alphaproteobacteria,2K4W8@204457|Sphingomonadales	204457|Sphingomonadales	S	Uncharacterized protein family UPF0016	-	-	-	-	-	-	-	-	-	-	-	-	UPF0016
CMS1_k127_2069149_10	1044.EH31_15320	8.142e-23	102.0	COG0267@1|root,COG0267@2|Bacteria,1N6QV@1224|Proteobacteria,2UF4D@28211|Alphaproteobacteria,2K6VC@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
CMS1_k127_2069149_6	745310.G432_12060	9.806e-52	185.0	COG0745@1|root,COG0745@2|Bacteria,1RD7E@1224|Proteobacteria,2U745@28211|Alphaproteobacteria,2K53C@204457|Sphingomonadales	204457|Sphingomonadales	T	response regulator	-	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
CMS1_k127_2069149_9	1207055.C100_01365	2.083e-24	105.0	2DMKE@1|root,32S6E@2|Bacteria,1NH3D@1224|Proteobacteria,2UHAS@28211|Alphaproteobacteria,2K72S@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF3572)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3572
CMS1_k127_2069149_3	1123270.ATUR01000004_gene1510	3.146e-74	258.0	COG0647@1|root,COG0647@2|Bacteria,1RBCP@1224|Proteobacteria,2U6MG@28211|Alphaproteobacteria,2KDJX@204457|Sphingomonadales	204457|Sphingomonadales	G	UMP catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2069149_5	1112214.AHIS01000003_gene1825	2.087e-57	203.0	COG0251@1|root,COG0251@2|Bacteria,1RHMZ@1224|Proteobacteria,2U9H4@28211|Alphaproteobacteria,2K4U7@204457|Sphingomonadales	204457|Sphingomonadales	J	endoribonuclease	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
CMS1_k127_2069149_2	1545915.JROG01000007_gene3078	2.074e-86	299.0	COG0584@1|root,COG0584@2|Bacteria,1MU8H@1224|Proteobacteria,2TV1D@28211|Alphaproteobacteria,2K3TX@204457|Sphingomonadales	204457|Sphingomonadales	C	glycerophosphoryl diester phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	GDPD
CMS1_k127_2069149_1	1123270.ATUR01000004_gene1508	8.123e-173	549.0	COG3146@1|root,COG3146@2|Bacteria,1MU35@1224|Proteobacteria,2TS5I@28211|Alphaproteobacteria,2K1NQ@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	ko:K09919	-	-	-	-	ko00000	-	-	-	FemAB_like
CMS1_k127_2069149_8	1545915.JROG01000007_gene3081	1.042e-37	144.0	COG0790@1|root,COG0790@2|Bacteria,1N8SR@1224|Proteobacteria,2UFFQ@28211|Alphaproteobacteria,2K5VX@204457|Sphingomonadales	204457|Sphingomonadales	S	FOG TPR repeat, SEL1 subfamily	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
CMS1_k127_2069149_11	317655.Sala_3003	7.774e-05	45.0	COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,2TS2D@28211|Alphaproteobacteria,2K0S2@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
CMS1_k127_2071516_1	1123269.NX02_24065	0.0	1196.0	COG1222@1|root,COG1222@2|Bacteria,1QTV4@1224|Proteobacteria,2U0Q7@28211|Alphaproteobacteria,2K0N9@204457|Sphingomonadales	204457|Sphingomonadales	O	Belongs to the AAA ATPase family	-	-	-	ko:K13525	ko04141,ko05134,map04141,map05134	M00400,M00403	-	-	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	3.A.16.1	-	-	AAA,CDC48_2,CDC48_N
CMS1_k127_2071516_7	1248760.ANFZ01000021_gene345	1.245e-164	529.0	COG0477@1|root,COG0477@2|Bacteria,1QUPF@1224|Proteobacteria,2U2HA@28211|Alphaproteobacteria,2K096@204457|Sphingomonadales	204457|Sphingomonadales	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_2071516_18	1545915.JROG01000003_gene1505	9.414e-40	149.0	COG2329@1|root,COG2329@2|Bacteria,1N062@1224|Proteobacteria,2UFFI@28211|Alphaproteobacteria,2K5W6@204457|Sphingomonadales	204457|Sphingomonadales	S	enzyme involved in biosynthesis of extracellular polysaccharides	-	-	-	-	-	-	-	-	-	-	-	-	ABM
CMS1_k127_2071516_9	1219035.NT2_05_02440	5.587e-89	297.0	COG3963@1|root,COG3963@2|Bacteria,1R81B@1224|Proteobacteria,2U46R@28211|Alphaproteobacteria,2K2HK@204457|Sphingomonadales	204457|Sphingomonadales	I	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS1_k127_2071516_2	1123270.ATUR01000004_gene1739	0.0	1173.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2TRFB@28211|Alphaproteobacteria,2K05M@204457|Sphingomonadales	204457|Sphingomonadales	S	Peptidase, M16	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
CMS1_k127_2071516_19	1537715.JQFJ01000002_gene2188	2.754e-37	142.0	2E6S2@1|root,33ASH@2|Bacteria,1N4U0@1224|Proteobacteria,2UC9M@28211|Alphaproteobacteria,2KEKD@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2071516_13	452662.SJA_C1-34210	5.138e-66	231.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,2U758@28211|Alphaproteobacteria,2K49Y@204457|Sphingomonadales	204457|Sphingomonadales	M	Belongs to the ompA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
CMS1_k127_2071516_3	1545915.JROG01000004_gene2490	4.364e-237	738.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,2TR03@28211|Alphaproteobacteria,2K1NT@204457|Sphingomonadales	204457|Sphingomonadales	U	Involved in the TonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
CMS1_k127_2071516_14	1248760.ANFZ01000004_gene2036	6.861e-61	219.0	COG5373@1|root,COG5373@2|Bacteria,1N5K2@1224|Proteobacteria,2UB74@28211|Alphaproteobacteria,2JZY7@204457|Sphingomonadales	204457|Sphingomonadales	S	membrane	tolA	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2071516_15	1248760.ANFZ01000004_gene2037	8.914e-54	194.0	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,2UA46@28211|Alphaproteobacteria,2K53V@204457|Sphingomonadales	204457|Sphingomonadales	U	Biopolymer transport protein	tolR	-	-	ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	ExbD
CMS1_k127_2071516_8	1537715.JQFJ01000005_gene205	7.124e-94	316.0	COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,2TQXQ@28211|Alphaproteobacteria,2K039@204457|Sphingomonadales	204457|Sphingomonadales	U	MotA TolQ ExbB proton channel	tolQ	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
CMS1_k127_2071516_17	1174684.EBMC1_00995	1.297e-51	186.0	COG0824@1|root,COG0824@2|Bacteria,1MZH6@1224|Proteobacteria,2UBYM@28211|Alphaproteobacteria,2K4JS@204457|Sphingomonadales	204457|Sphingomonadales	S	thioesterase	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
CMS1_k127_2071516_22	1348663.KCH_16640	0.0001454	46.0	COG0640@1|root,COG3832@1|root,COG0640@2|Bacteria,COG3832@2|Bacteria,2GNW2@201174|Actinobacteria,2M3WE@2063|Kitasatospora	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1,HTH_20
CMS1_k127_2071516_4	745310.G432_10805	1.046e-236	745.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,2TSZZ@28211|Alphaproteobacteria,2K1RR@204457|Sphingomonadales	204457|Sphingomonadales	Q	Amidohydrolase family	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
CMS1_k127_2071516_6	1248760.ANFZ01000002_gene3122	2.134e-194	618.0	COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,2TR5B@28211|Alphaproteobacteria,2K0AI@204457|Sphingomonadales	204457|Sphingomonadales	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
CMS1_k127_2071516_16	1545915.JROG01000009_gene2762	3.518e-52	188.0	COG0346@1|root,COG0346@2|Bacteria,1N1D4@1224|Proteobacteria,2UBYV@28211|Alphaproteobacteria,2K6AI@204457|Sphingomonadales	204457|Sphingomonadales	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS1_k127_2071516_20	1280941.HY2_04780	2.413e-34	137.0	COG0346@1|root,COG0346@2|Bacteria,1N1D4@1224|Proteobacteria,2UGZ0@28211|Alphaproteobacteria,43ZRH@69657|Hyphomonadaceae	28211|Alphaproteobacteria	E	Glyoxalase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS1_k127_2071516_21	1248760.ANFZ01000002_gene3125	1.102e-33	136.0	2EHBD@1|root,33B38@2|Bacteria,1MZRE@1224|Proteobacteria,2UE9D@28211|Alphaproteobacteria,2K709@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF3617)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3617
CMS1_k127_2071516_0	46429.BV95_04074	0.0	1249.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,2TQSP@28211|Alphaproteobacteria,2K0F9@204457|Sphingomonadales	204457|Sphingomonadales	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
CMS1_k127_2071516_11	1144307.PMI04_02841	5.729e-74	258.0	COG4798@1|root,COG4798@2|Bacteria,1RHGZ@1224|Proteobacteria,2U69N@28211|Alphaproteobacteria,2KDKH@204457|Sphingomonadales	204457|Sphingomonadales	S	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,PCMT
CMS1_k127_2071516_12	745310.G432_16400	7.812e-74	254.0	COG1225@1|root,COG1225@2|Bacteria,1RD2X@1224|Proteobacteria,2U7PM@28211|Alphaproteobacteria,2K8KP@204457|Sphingomonadales	204457|Sphingomonadales	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS1_k127_2071516_5	1248760.ANFZ01000002_gene3129	2.767e-229	729.0	COG4232@1|root,COG4233@1|root,COG4232@2|Bacteria,COG4233@2|Bacteria,1MU8W@1224|Proteobacteria,2TTUM@28211|Alphaproteobacteria,2K11D@204457|Sphingomonadales	204457|Sphingomonadales	CO	Thiol disulfide interchange protein	-	-	-	-	-	-	-	-	-	-	-	-	DsbC,DsbD,Thioredoxin_7
CMS1_k127_2071516_10	1112216.JH594425_gene2454	4.019e-85	291.0	COG1524@1|root,COG1524@2|Bacteria,1R5V5@1224|Proteobacteria,2U4ZG@28211|Alphaproteobacteria,2K230@204457|Sphingomonadales	204457|Sphingomonadales	S	Alkaline phosphatase with broad substrate specificity	-	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Phosphodiest
CMS1_k127_2073762_5	450851.PHZ_c2408	7.88e-288	901.0	COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,2UPQH@28211|Alphaproteobacteria,2KHUY@204458|Caulobacterales	204458|Caulobacterales	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
CMS1_k127_2073762_15	450851.PHZ_c2409	4.064e-91	308.0	COG4126@1|root,COG4126@2|Bacteria,1MVNB@1224|Proteobacteria,2U28G@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Hydantoin racemase	-	-	-	-	-	-	-	-	-	-	-	-	Asp_Glu_race
CMS1_k127_2073762_12	450851.PHZ_c2412	1.33e-157	504.0	COG3535@1|root,COG3535@2|Bacteria,1NCBV@1224|Proteobacteria,2TU70@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF917)	-	-	-	ko:K09703	-	-	-	-	ko00000	-	-	-	DUF917
CMS1_k127_2073762_8	450851.PHZ_c2411	1.679e-209	663.0	COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,2TRBN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EQ	N-methylhydantoinase A acetone carboxylase, beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Hydant_A_N,Hydantoinase_A
CMS1_k127_2073762_11	685035.ADAE01000018_gene495	1.423e-170	564.0	COG2909@1|root,COG2909@2|Bacteria,1N56E@1224|Proteobacteria,2UF2Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
CMS1_k127_2073762_13	1219035.NT2_05_01860	3.185e-157	501.0	COG2130@1|root,COG2130@2|Bacteria,1MUC2@1224|Proteobacteria,2TQYM@28211|Alphaproteobacteria,2K9AC@204457|Sphingomonadales	204457|Sphingomonadales	S	N-terminal domain of oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N_2,ADH_zinc_N
CMS1_k127_2073762_10	1219035.NT2_05_01870	8.472e-179	568.0	COG0183@1|root,COG0183@2|Bacteria,1MU8C@1224|Proteobacteria,2TS6P@28211|Alphaproteobacteria,2KDA0@204457|Sphingomonadales	204457|Sphingomonadales	I	Belongs to the thiolase family	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
CMS1_k127_2073762_4	1219035.NT2_05_01880	2.073e-295	932.0	COG2909@1|root,COG2909@2|Bacteria,1MVZZ@1224|Proteobacteria,2U296@28211|Alphaproteobacteria,2K5S0@204457|Sphingomonadales	204457|Sphingomonadales	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,GerE
CMS1_k127_2073762_6	1219035.NT2_05_01890	1.569e-240	758.0	COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,2TQZ6@28211|Alphaproteobacteria,2K20D@204457|Sphingomonadales	204457|Sphingomonadales	EQ	PFAM Hydantoinase oxoprolinase	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
CMS1_k127_2073762_17	1219035.NT2_05_01900	5.105e-66	228.0	COG4647@1|root,COG4647@2|Bacteria,1RD95@1224|Proteobacteria,2U7A1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Acetone carboxylase, gamma subunit	-	-	6.4.1.6	ko:K10856	-	-	-	-	ko00000,ko01000	-	-	-	Acetone_carb_G
CMS1_k127_2073762_1	1219035.NT2_05_01910	0.0	1177.0	COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,2TQZ6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EQ	N-methylhydantoinase A acetone carboxylase, beta subunit	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
CMS1_k127_2073762_0	1219035.NT2_05_01920	0.0	1303.0	COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,2TR3I@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EQ	acetone carboxylase, alpha subunit	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
CMS1_k127_2073762_20	402881.Plav_1153	7.97e-11	71.0	28KRF@1|root,2ZA8Z@2|Bacteria,1R9AM@1224|Proteobacteria,2U4SW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2073762_7	1219035.NT2_05_01940	1.986e-233	734.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,2K1MV@204457|Sphingomonadales	204457|Sphingomonadales	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
CMS1_k127_2073762_14	13690.CP98_03229	1.817e-154	498.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TR15@28211|Alphaproteobacteria,2K1CR@204457|Sphingomonadales	204457|Sphingomonadales	I	acyl-CoA dehydrogenase	-	-	1.3.8.8	ko:K00255	ko00071,ko01100,ko01212,ko03320,map00071,map01100,map01212,map03320	M00087	R01279,R03777,R03857,R03990,R04751,R04754	RC00052	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS1_k127_2073762_2	1219035.NT2_05_01950	0.0	1138.0	COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,2UPF7@28211|Alphaproteobacteria,2K99S@204457|Sphingomonadales	204457|Sphingomonadales	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
CMS1_k127_2073762_9	1112216.JH594425_gene71	6.087e-199	638.0	COG2982@1|root,COG2982@2|Bacteria,1MUAN@1224|Proteobacteria,2U4Y3@28211|Alphaproteobacteria,2JZWM@204457|Sphingomonadales	204457|Sphingomonadales	M	AsmA-like C-terminal region	-	-	-	ko:K07290	-	-	-	-	ko00000	9.B.121	-	-	AsmA,AsmA_2
CMS1_k127_2073762_3	1044.EH31_00405	4.901e-319	978.0	COG0388@1|root,COG3153@1|root,COG0388@2|Bacteria,COG3153@2|Bacteria,1MX4I@1224|Proteobacteria,2TVMQ@28211|Alphaproteobacteria,2K105@204457|Sphingomonadales	204457|Sphingomonadales	K	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,CN_hydrolase
CMS1_k127_2073762_16	1382304.JNIL01000001_gene501	1.186e-70	247.0	COG1028@1|root,COG1028@2|Bacteria,1U2GS@1239|Firmicutes,4H9R9@91061|Bacilli,278AY@186823|Alicyclobacillaceae	91061|Bacilli	IQ	PFAM short-chain dehydrogenase reductase SDR	fabG1	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS1_k127_2073762_19	1207055.C100_15815	3.876e-23	104.0	COG0848@1|root,COG0848@2|Bacteria,1RHDF@1224|Proteobacteria,2UEA0@28211|Alphaproteobacteria,2K55Z@204457|Sphingomonadales	204457|Sphingomonadales	U	Biopolymer transport protein	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
CMS1_k127_2073762_18	1248760.ANFZ01000009_gene1476	4.414e-42	156.0	COG1566@1|root,COG1566@2|Bacteria,1R50C@1224|Proteobacteria,2TUCN@28211|Alphaproteobacteria,2K0QD@204457|Sphingomonadales	204457|Sphingomonadales	V	Protein of unknown function (DUF3667)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3667
CMS1_k127_2082197_2	1248760.ANFZ01000013_gene1823	7.057e-178	571.0	COG1505@1|root,COG1505@2|Bacteria,1NZ7N@1224|Proteobacteria,2TW70@28211|Alphaproteobacteria,2K10C@204457|Sphingomonadales	204457|Sphingomonadales	E	Prolyl oligopeptidase	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
CMS1_k127_2082197_6	702113.PP1Y_AT17159	2.642e-60	211.0	COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,2U749@28211|Alphaproteobacteria,2K4J0@204457|Sphingomonadales	204457|Sphingomonadales	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
CMS1_k127_2082197_0	1219035.NT2_02_02960	4.148e-200	626.0	COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,2TSI0@28211|Alphaproteobacteria,2K0R2@204457|Sphingomonadales	204457|Sphingomonadales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
CMS1_k127_2082197_4	1123270.ATUR01000003_gene1168	4.482e-71	241.0	COG0100@1|root,COG0100@2|Bacteria,1RD0A@1224|Proteobacteria,2U717@28211|Alphaproteobacteria,2K3VT@204457|Sphingomonadales	204457|Sphingomonadales	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
CMS1_k127_2082197_5	1144305.PMI02_02074	1.88e-60	211.0	COG0099@1|root,COG0099@2|Bacteria,1RD1G@1224|Proteobacteria,2U73D@28211|Alphaproteobacteria,2K4E3@204457|Sphingomonadales	204457|Sphingomonadales	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
CMS1_k127_2082197_3	1248760.ANFZ01000013_gene1818	8.741e-123	404.0	COG3608@1|root,COG3608@2|Bacteria,1MUAA@1224|Proteobacteria,2TRVI@28211|Alphaproteobacteria,2K2C1@204457|Sphingomonadales	204457|Sphingomonadales	S	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
CMS1_k127_2082197_1	314225.ELI_07390	4.772e-178	559.0	COG0189@1|root,COG0189@2|Bacteria,1MX62@1224|Proteobacteria,2TRUH@28211|Alphaproteobacteria,2K29D@204457|Sphingomonadales	204457|Sphingomonadales	HJ	Belongs to the RimK family	rimK	-	6.3.2.32	ko:K05844,ko:K14940	ko00680,ko01120,map00680,map01120	-	R09401	RC00064,RC00090	ko00000,ko00001,ko01000,ko03009	-	-	-	RimK
CMS1_k127_2082197_7	1123270.ATUR01000003_gene1171	3.942e-26	109.0	COG4067@1|root,COG4067@2|Bacteria,1RGX8@1224|Proteobacteria,2UC5Z@28211|Alphaproteobacteria,2K6SX@204457|Sphingomonadales	204457|Sphingomonadales	O	Ribosomal protein S6 modification protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn_protease
CMS1_k127_2102991_0	627192.SLG_00730	9.384e-192	609.0	COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,2TRBQ@28211|Alphaproteobacteria,2K1J3@204457|Sphingomonadales	204457|Sphingomonadales	C	E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
CMS1_k127_2102991_2	1219035.NT2_02_02870	1.362e-166	526.0	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,2TQKB@28211|Alphaproteobacteria,2K1F5@204457|Sphingomonadales	204457|Sphingomonadales	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
CMS1_k127_2102991_1	1081640.AGFU01000020_gene1886	3.749e-171	541.0	COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,2TSV6@28211|Alphaproteobacteria,2K17I@204457|Sphingomonadales	204457|Sphingomonadales	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
CMS1_k127_2102991_3	1174684.EBMC1_04309	5.219e-42	160.0	2DB8I@1|root,2Z7RY@2|Bacteria,1MY4M@1224|Proteobacteria,2U2A8@28211|Alphaproteobacteria,2K1YC@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2111331_4	1123270.ATUR01000002_gene2436	9.993e-65	226.0	COG4964@1|root,COG4964@2|Bacteria,1MV8G@1224|Proteobacteria,2TRNN@28211|Alphaproteobacteria,2K0ZQ@204457|Sphingomonadales	204457|Sphingomonadales	U	Belongs to the GSP D family	cpaC	-	-	ko:K02280	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	BON,Secretin,T2SS-T3SS_pil_N
CMS1_k127_2111331_5	702113.PP1Y_AT19175	1.951e-54	197.0	COG5461@1|root,COG5461@2|Bacteria,1REYP@1224|Proteobacteria,2U8J3@28211|Alphaproteobacteria,2K5AY@204457|Sphingomonadales	204457|Sphingomonadales	N	Pilus assembly protein CpaD	cpaD	-	-	ko:K02281	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Pilus_CpaD
CMS1_k127_2111331_1	1248760.ANFZ01000006_gene2378	2.431e-190	602.0	COG2204@1|root,COG4963@1|root,COG2204@2|Bacteria,COG4963@2|Bacteria,1MWNY@1224|Proteobacteria,2TUDS@28211|Alphaproteobacteria,2K0BT@204457|Sphingomonadales	204457|Sphingomonadales	TU	Flp pilus assembly protein, ATPase CpaE	cpaE	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	CbiA,ParA
CMS1_k127_2111331_3	383381.EH30_01575	2.941e-118	389.0	COG4965@1|root,COG4965@2|Bacteria,1MUXK@1224|Proteobacteria,2TRBI@28211|Alphaproteobacteria,2K0B5@204457|Sphingomonadales	204457|Sphingomonadales	U	pilus assembly protein TadB	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
CMS1_k127_2111331_2	629773.AORY01000004_gene348	2.715e-144	464.0	COG2064@1|root,COG2064@2|Bacteria,1MWAZ@1224|Proteobacteria,2TSFA@28211|Alphaproteobacteria,2K03P@204457|Sphingomonadales	204457|Sphingomonadales	NU	type II secretion system protein	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
CMS1_k127_2111331_6	1248760.ANFZ01000009_gene1408	2.899e-48	176.0	COG1846@1|root,COG1846@2|Bacteria,1N1CJ@1224|Proteobacteria,2UCHN@28211|Alphaproteobacteria,2K5C8@204457|Sphingomonadales	204457|Sphingomonadales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
CMS1_k127_2111331_0	1545915.JROG01000003_gene1170	1.44e-245	777.0	COG4206@1|root,COG4206@2|Bacteria,1R1WX@1224|Proteobacteria,2U0GK@28211|Alphaproteobacteria,2K1DC@204457|Sphingomonadales	204457|Sphingomonadales	H	receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
CMS1_k127_2111331_7	1502850.FG91_00178	1.323e-05	47.0	COG0625@1|root,COG0625@2|Bacteria,1RA4Y@1224|Proteobacteria,2U5B6@28211|Alphaproteobacteria,2K49D@204457|Sphingomonadales	204457|Sphingomonadales	O	maleylacetoacetate isomerase	-	-	5.2.1.2,5.2.1.4	ko:K01800,ko:K01801	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R03181,R03868	RC00867	ko00000,ko00001,ko00002,ko01000	-	-	-	GST_C_2,GST_N,GST_N_3
CMS1_k127_2162816_4	1346791.M529_06230	2.713e-08	57.0	COG0494@1|root,COG0494@2|Bacteria,1RD2C@1224|Proteobacteria,2TV3Q@28211|Alphaproteobacteria,2K3ZW@204457|Sphingomonadales	204457|Sphingomonadales	L	Nudix hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS1_k127_2162816_2	1549858.MC45_11630	1.044e-72	249.0	COG3816@1|root,COG3816@2|Bacteria,1RD5Q@1224|Proteobacteria,2U7DA@28211|Alphaproteobacteria,2K0YC@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	ko:K09986	-	-	-	-	ko00000	-	-	-	DUF1285
CMS1_k127_2162816_3	279238.Saro_1024	1.233e-61	216.0	COG3153@1|root,COG3153@2|Bacteria,1RD0C@1224|Proteobacteria,2U7AS@28211|Alphaproteobacteria,2K560@204457|Sphingomonadales	204457|Sphingomonadales	S	Acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_9
CMS1_k127_2162816_1	1123270.ATUR01000002_gene2370	6.026e-83	284.0	COG4446@1|root,COG4446@2|Bacteria,1N31A@1224|Proteobacteria,2U0NZ@28211|Alphaproteobacteria,2K52C@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF1499)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1499
CMS1_k127_2162816_0	1429851.X548_00185	6.002e-108	352.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,1RNGN@1236|Gammaproteobacteria,1X362@135614|Xanthomonadales	135614|Xanthomonadales	G	Dehydrogenase	yliI	-	-	-	-	-	-	-	-	-	-	-	GSDH
CMS1_k127_2189574_6	1248760.ANFZ01000006_gene2678	2.086e-139	447.0	COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,2TSFS@28211|Alphaproteobacteria,2K1E7@204457|Sphingomonadales	204457|Sphingomonadales	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,Na_sulph_symp,TrkA_C
CMS1_k127_2189574_2	161528.ED21_22793	2.277e-220	689.0	COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,2TRET@28211|Alphaproteobacteria,2K103@204457|Sphingomonadales	204457|Sphingomonadales	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
CMS1_k127_2189574_4	685778.AORL01000021_gene662	1.106e-142	463.0	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,2TTQ2@28211|Alphaproteobacteria,2K10A@204457|Sphingomonadales	204457|Sphingomonadales	D	rod shape-determining protein MreB	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
CMS1_k127_2189574_1	685778.AORL01000004_gene3486	2.187e-246	764.0	COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,2TRKY@28211|Alphaproteobacteria,2K0T7@204457|Sphingomonadales	204457|Sphingomonadales	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
CMS1_k127_2189574_5	46429.BV95_01081	8.551e-141	456.0	COG3705@1|root,COG3705@2|Bacteria,1MWIG@1224|Proteobacteria,2TSVG@28211|Alphaproteobacteria,2K0AG@204457|Sphingomonadales	204457|Sphingomonadales	E	tRNA synthetase, class II	hisZ	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
CMS1_k127_2189574_0	1123270.ATUR01000008_gene385	2.524e-278	862.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,2TR0F@28211|Alphaproteobacteria,2K0J0@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
CMS1_k127_2189574_3	1123270.ATUR01000008_gene383	1.135e-209	655.0	COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,2TSHT@28211|Alphaproteobacteria,2K0J1@204457|Sphingomonadales	204457|Sphingomonadales	EH	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
CMS1_k127_2189574_10	1545915.JROG01000004_gene2399	2.42e-76	262.0	COG3921@1|root,COG3921@2|Bacteria,1N3WR@1224|Proteobacteria,2U5JD@28211|Alphaproteobacteria,2K058@204457|Sphingomonadales	204457|Sphingomonadales	S	Extensin-like protein C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Extensin-like_C
CMS1_k127_2189574_7	1545915.JROG01000004_gene2398	1.481e-135	436.0	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,2TR90@28211|Alphaproteobacteria,2K00V@204457|Sphingomonadales	204457|Sphingomonadales	S	Rossmann fold nucleotide-binding protein	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
CMS1_k127_2189574_11	1545915.JROG01000003_gene1030	3.412e-76	262.0	COG3474@1|root,COG3474@2|Bacteria,1RIDN@1224|Proteobacteria,2U142@28211|Alphaproteobacteria,2K42S@204457|Sphingomonadales	204457|Sphingomonadales	C	cytochrome C	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C
CMS1_k127_2189574_8	1114964.L485_16005	2.255e-129	420.0	COG0077@1|root,COG0077@2|Bacteria,1MU60@1224|Proteobacteria,2TSUT@28211|Alphaproteobacteria,2K0AM@204457|Sphingomonadales	204457|Sphingomonadales	E	Prephenate dehydratase	-	-	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	PDT
CMS1_k127_2189574_9	439496.RBY4I_1120	8.228e-103	348.0	COG2040@1|root,COG2040@2|Bacteria,1MUXU@1224|Proteobacteria,2TURU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	homocysteine	-	-	2.1.1.10	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	-	R00650	RC00003,RC00035	ko00000,ko00001,ko01000	-	-	-	S-methyl_trans
CMS1_k127_2189574_12	1079460.ATTQ01000005_gene2082	1.655e-11	67.0	COG1309@1|root,COG1309@2|Bacteria,1RC7C@1224|Proteobacteria,2U5YR@28211|Alphaproteobacteria,4B8MP@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS1_k127_2212553_4	1219035.NT2_05_03920	1.482e-31	129.0	COG2001@1|root,COG2001@2|Bacteria,1RHCS@1224|Proteobacteria,2UBJA@28211|Alphaproteobacteria,2K5SD@204457|Sphingomonadales	204457|Sphingomonadales	K	Belongs to the MraZ family	-	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	-
CMS1_k127_2212553_3	1123269.NX02_00690	2.108e-38	153.0	COG3225@1|root,COG3225@2|Bacteria,1NAUG@1224|Proteobacteria,2VGXX@28211|Alphaproteobacteria,2KE7D@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2212553_0	1248760.ANFZ01000006_gene2350	1.423e-180	568.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,2TR4W@28211|Alphaproteobacteria,2K0XR@204457|Sphingomonadales	204457|Sphingomonadales	E	Cysteine synthase	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS1_k127_2212553_2	161528.ED21_25036	2.985e-51	186.0	COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,2V64V@28211|Alphaproteobacteria,2KAAH@204457|Sphingomonadales	204457|Sphingomonadales	O	FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
CMS1_k127_2212553_1	1123267.JONN01000001_gene1203	2.371e-132	445.0	COG0457@1|root,COG0457@2|Bacteria,1N0A9@1224|Proteobacteria,2TTMN@28211|Alphaproteobacteria,2K2YU@204457|Sphingomonadales	204457|Sphingomonadales	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_8
CMS1_k127_2213763_13	1123270.ATUR01000006_gene112	9.254e-77	260.0	COG1432@1|root,COG1432@2|Bacteria,1MX5C@1224|Proteobacteria,2TRE6@28211|Alphaproteobacteria,2K1CX@204457|Sphingomonadales	204457|Sphingomonadales	S	OST-HTH/LOTUS domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
CMS1_k127_2213763_16	1123270.ATUR01000006_gene114	5.199e-61	219.0	COG0259@1|root,COG0259@2|Bacteria,1RIAU@1224|Proteobacteria,2UBET@28211|Alphaproteobacteria,2K4DS@204457|Sphingomonadales	204457|Sphingomonadales	H	Pyridoxamine 5'-phosphate oxidase	-	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	Putative_PNPOx,Pyridox_oxase_2
CMS1_k127_2213763_10	1174684.EBMC1_16739	1.006e-96	319.0	COG0288@1|root,COG0288@2|Bacteria,1MV1U@1224|Proteobacteria,2VEYE@28211|Alphaproteobacteria,2KDW2@204457|Sphingomonadales	204457|Sphingomonadales	P	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
CMS1_k127_2213763_2	1248760.ANFZ01000009_gene1173	5.153e-172	543.0	COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,2TRP3@28211|Alphaproteobacteria,2K1H4@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
CMS1_k127_2213763_18	317655.Sala_1280	7.158e-56	200.0	COG2867@1|root,COG2867@2|Bacteria,1RGUH@1224|Proteobacteria,2U7D8@28211|Alphaproteobacteria,2K41W@204457|Sphingomonadales	204457|Sphingomonadales	I	Oligoketide cyclase lipid transport protein	-	-	-	ko:K18588	-	-	-	-	ko00000	-	-	-	Polyketide_cyc
CMS1_k127_2213763_15	1549858.MC45_03005	2.079e-66	230.0	COG1546@1|root,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,2U94H@28211|Alphaproteobacteria,2K40Q@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the CinA family	-	-	3.5.1.42	ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA
CMS1_k127_2213763_7	13689.BV96_01811	1.025e-134	439.0	COG0245@1|root,COG1211@1|root,COG0245@2|Bacteria,COG1211@2|Bacteria,1MVHA@1224|Proteobacteria,2TRQC@28211|Alphaproteobacteria,2K0Y0@204457|Sphingomonadales	204457|Sphingomonadales	I	Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF)	ispDF	-	2.7.7.60,4.6.1.12	ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
CMS1_k127_2213763_3	1248760.ANFZ01000009_gene1168	5.085e-170	538.0	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,2TRC8@28211|Alphaproteobacteria,2K0QH@204457|Sphingomonadales	204457|Sphingomonadales	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
CMS1_k127_2213763_12	158500.BV97_01580	5.7e-82	287.0	COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,2TQS1@28211|Alphaproteobacteria,2K1YJ@204457|Sphingomonadales	204457|Sphingomonadales	T	Histidine kinase	ntrB	-	2.7.13.3	ko:K07708	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4
CMS1_k127_2213763_4	1545915.JROG01000003_gene967	6.118e-167	538.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria,2K0MW@204457|Sphingomonadales	204457|Sphingomonadales	T	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	ntrC	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS1_k127_2213763_0	1114964.L485_20160	1.355e-261	826.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,2TQTB@28211|Alphaproteobacteria,2K01N@204457|Sphingomonadales	204457|Sphingomonadales	T	Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation	ntrY	-	2.7.13.3	ko:K13598	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
CMS1_k127_2213763_1	1123270.ATUR01000006_gene122	9.312e-213	668.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQW2@28211|Alphaproteobacteria,2K1KM@204457|Sphingomonadales	204457|Sphingomonadales	T	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	ntrX	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS1_k127_2213763_14	1123270.ATUR01000006_gene123	5.245e-73	248.0	COG1923@1|root,COG1923@2|Bacteria,1MZM1@1224|Proteobacteria,2UBTW@28211|Alphaproteobacteria,2K2YT@204457|Sphingomonadales	204457|Sphingomonadales	J	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs	hfq	-	-	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	-	-	-	ko00000,ko00001,ko03019,ko03036	-	-	-	Hfq
CMS1_k127_2213763_5	745310.G432_01180	8.221e-164	527.0	COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,2TUXJ@28211|Alphaproteobacteria,2K0SI@204457|Sphingomonadales	204457|Sphingomonadales	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
CMS1_k127_2213763_11	627192.SLG_17920	5.228e-85	288.0	COG1694@1|root,COG3956@2|Bacteria,1MVKM@1224|Proteobacteria,2TRC9@28211|Alphaproteobacteria,2K0DA@204457|Sphingomonadales	204457|Sphingomonadales	S	MazG family	mazG	-	3.6.1.9	ko:K04765	ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100	-	R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R03004,R03036,R11323	RC00002	ko00000,ko00001,ko01000	-	-	-	MazG
CMS1_k127_2213763_17	1081640.AGFU01000014_gene2101	2.335e-56	203.0	COG3577@1|root,COG3577@2|Bacteria,1R74B@1224|Proteobacteria,2UBEE@28211|Alphaproteobacteria,2K1P8@204457|Sphingomonadales	204457|Sphingomonadales	S	gag-polyprotein putative aspartyl protease	-	-	-	ko:K06985	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	gag-asp_proteas
CMS1_k127_2213763_9	392499.Swit_0488	7.708e-101	335.0	COG1235@1|root,COG1235@2|Bacteria,1MVJH@1224|Proteobacteria,2TQQN@28211|Alphaproteobacteria,2K1KQ@204457|Sphingomonadales	204457|Sphingomonadales	S	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I	-	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
CMS1_k127_2213763_8	1007104.SUS17_325	1.558e-132	425.0	COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,2TS88@28211|Alphaproteobacteria,2K0X6@204457|Sphingomonadales	204457|Sphingomonadales	L	LuxR family transcriptional regulator	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
CMS1_k127_2213763_6	1112214.AHIS01000094_gene551	1.865e-142	458.0	COG0143@1|root,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,2TQKA@28211|Alphaproteobacteria,2K0VF@204457|Sphingomonadales	204457|Sphingomonadales	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g
CMS1_k127_2218604_7	1112216.JH594425_gene1714	6.593e-104	340.0	COG2710@1|root,COG2710@2|Bacteria,1MVP0@1224|Proteobacteria,2TSK1@28211|Alphaproteobacteria,2K0EI@204457|Sphingomonadales	204457|Sphingomonadales	C	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex	bchN	-	1.3.7.7	ko:K04038	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06282	RC01008	ko00000,ko00001,ko01000	-	-	-	Oxidored_nitro
CMS1_k127_2218604_2	519989.ECTPHS_08161	3.052e-227	717.0	COG2710@1|root,COG2710@2|Bacteria,1MWQ4@1224|Proteobacteria,1RQR5@1236|Gammaproteobacteria,1WXMP@135613|Chromatiales	135613|Chromatiales	F	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex	bchB	-	1.3.7.7	ko:K04039	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06282	RC01008	ko00000,ko00001,ko01000	-	-	-	Oxidored_nitro,PCP_red
CMS1_k127_2218604_0	1248760.ANFZ01000023_gene107	0.0	1817.0	COG1429@1|root,COG1429@2|Bacteria,1MU5W@1224|Proteobacteria,2TQVD@28211|Alphaproteobacteria,2K02Q@204457|Sphingomonadales	204457|Sphingomonadales	H	CobN/Magnesium Chelatase	bchH	-	6.6.1.1,6.6.1.2	ko:K02230,ko:K03403	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877,R05227	RC01012,RC02000	ko00000,ko00001,ko01000	-	-	-	CobN-Mg_chel,DUF3479
CMS1_k127_2218604_5	1122970.AUHC01000004_gene2260	4.766e-162	516.0	COG1348@1|root,COG1348@2|Bacteria,1MVTE@1224|Proteobacteria,2TSKC@28211|Alphaproteobacteria,2K1YK@204457|Sphingomonadales	204457|Sphingomonadales	D	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP	nifH	-	1.18.6.1,1.3.7.7	ko:K02588,ko:K04037	ko00625,ko00860,ko00910,ko01100,ko01110,ko01120,map00625,map00860,map00910,map01100,map01110,map01120	M00175	R05185,R05496,R06282	RC00002,RC01008,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_NifH
CMS1_k127_2218604_8	1248760.ANFZ01000023_gene109	8.113e-80	272.0	COG2227@1|root,COG2227@2|Bacteria,1N2VZ@1224|Proteobacteria,2TU4Z@28211|Alphaproteobacteria,2K2H0@204457|Sphingomonadales	204457|Sphingomonadales	H	Magnesium-protoporphyrin IX methyltransferase C-terminus	-	-	2.1.1.11	ko:K03428	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R04237	RC00003,RC00460	ko00000,ko00001,ko01000	-	-	-	MTS,Mg-por_mtran_C,PrmA
CMS1_k127_2218604_3	1545915.JROG01000009_gene2693	1.67e-190	607.0	COG0477@1|root,COG2814@2|Bacteria,1MW95@1224|Proteobacteria,2TS8H@28211|Alphaproteobacteria,2K2JK@204457|Sphingomonadales	204457|Sphingomonadales	EGP	PUCC protein	-	-	-	ko:K08226	-	-	-	-	ko00000,ko02000	2.A.1.41	-	-	PUCC
CMS1_k127_2218604_6	685035.ADAE01000008_gene2882	3.585e-104	344.0	COG3861@1|root,COG3861@2|Bacteria,1NU42@1224|Proteobacteria,2TTV5@28211|Alphaproteobacteria,2K0VQ@204457|Sphingomonadales	204457|Sphingomonadales	S	Photosynthetic reaction centre, H-chain N-terminal region	-	-	-	ko:K13991	ko02020,map02020	-	-	-	ko00000,ko00001,ko00194	-	-	-	PRC,PRCH
CMS1_k127_2218604_11	1545915.JROG01000009_gene2695	1.367e-54	200.0	COG3428@1|root,COG3428@2|Bacteria,1RHA4@1224|Proteobacteria,2UA6D@28211|Alphaproteobacteria,2K1SW@204457|Sphingomonadales	204457|Sphingomonadales	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
CMS1_k127_2218604_13	685035.ADAE01000008_gene2880	3.359e-31	132.0	2E3IS@1|root,32YH7@2|Bacteria,1N9I5@1224|Proteobacteria,2UGHF@28211|Alphaproteobacteria,2K6HN@204457|Sphingomonadales	204457|Sphingomonadales	S	Photosynthetic complex assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2218604_14	1550073.JROH01000005_gene1620	5.248e-27	119.0	2E7QH@1|root,3325Y@2|Bacteria,1MZ3C@1224|Proteobacteria,2UG5F@28211|Alphaproteobacteria,2K66G@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2218604_4	1248760.ANFZ01000023_gene115	8.739e-175	554.0	COG1633@1|root,COG1633@2|Bacteria,1N5FH@1224|Proteobacteria,2TU0E@28211|Alphaproteobacteria,2K1MB@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	acsF	-	1.14.13.81	ko:K04035	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06265,R06266,R06267,R10068	RC00741,RC01491,RC01492,RC03042	ko00000,ko00001,ko01000	-	-	-	Rubrerythrin
CMS1_k127_2218604_10	383381.EH30_09835	1.901e-62	225.0	COG0523@1|root,COG0523@2|Bacteria,1MY4T@1224|Proteobacteria,2U0DU@28211|Alphaproteobacteria,2K41B@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF3623)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3623
CMS1_k127_2218604_1	383381.EH30_09840	5.425e-228	709.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,2TQXI@28211|Alphaproteobacteria,2K08Q@204457|Sphingomonadales	204457|Sphingomonadales	E	5-aminolevulinic acid synthase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
CMS1_k127_2218604_12	1545915.JROG01000009_gene2701	8.712e-52	188.0	COG3474@1|root,COG3474@2|Bacteria,1MZGS@1224|Proteobacteria,2UCUT@28211|Alphaproteobacteria,2K4M2@204457|Sphingomonadales	204457|Sphingomonadales	C	Cytochrome c	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C
CMS1_k127_2218604_9	685035.ADAE01000008_gene2873	4.454e-78	269.0	COG4949@1|root,COG4949@2|Bacteria,1MVI2@1224|Proteobacteria,2TSQJ@28211|Alphaproteobacteria,2K3GF@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF3422)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3422
CMS1_k127_2221803_8	1545915.JROG01000004_gene1763	1.222e-46	169.0	COG1972@1|root,COG1972@2|Bacteria,1MXXX@1224|Proteobacteria,2TU8A@28211|Alphaproteobacteria,2K07T@204457|Sphingomonadales	204457|Sphingomonadales	F	nucleoside	-	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
CMS1_k127_2221803_6	745310.G432_09750	7.143e-146	467.0	COG3491@1|root,COG3491@2|Bacteria,1MUNT@1224|Proteobacteria,2TU3Y@28211|Alphaproteobacteria,2K1Y3@204457|Sphingomonadales	204457|Sphingomonadales	C	Belongs to the iron ascorbate-dependent oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy,DIOX_N
CMS1_k127_2221803_9	1123059.KB823012_gene2125	7.148e-46	173.0	COG0572@1|root,COG0572@2|Bacteria,1MWCH@1224|Proteobacteria,2U6NE@28211|Alphaproteobacteria,43XMF@69657|Hyphomonadaceae	28211|Alphaproteobacteria	F	Belongs to the uridine kinase family	-	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
CMS1_k127_2221803_0	314225.ELI_11175	0.0	1248.0	COG1629@1|root,COG4771@2|Bacteria,1N6JG@1224|Proteobacteria,2TSK9@28211|Alphaproteobacteria,2KCG3@204457|Sphingomonadales	204457|Sphingomonadales	P	membrane	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS1_k127_2221803_5	1550073.JROH01000033_gene2761	7.014e-165	524.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,2TSIP@28211|Alphaproteobacteria,2K0VH@204457|Sphingomonadales	204457|Sphingomonadales	M	epimerase dehydratase	-	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase
CMS1_k127_2221803_7	1030157.AFMP01000059_gene2803	4.646e-74	254.0	COG0431@1|root,COG0431@2|Bacteria,1RB2T@1224|Proteobacteria,2U6RE@28211|Alphaproteobacteria,2K1QH@204457|Sphingomonadales	204457|Sphingomonadales	S	NADPH-dependent FMN reductase	-	-	1.5.1.38	ko:K00299	ko00740,ko00920,ko01100,map00740,map00920,map01100	-	R05706,R07210,R10206	RC00126,RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	FMN_red
CMS1_k127_2221803_4	1247963.JPHU01000008_gene2889	5.095e-195	614.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TR15@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS1_k127_2221803_3	1123059.KB823011_gene1575	2.694e-195	616.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2TS1R@28211|Alphaproteobacteria,43WRV@69657|Hyphomonadaceae	28211|Alphaproteobacteria	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
CMS1_k127_2221803_1	1247963.JPHU01000001_gene1812	1.002e-291	912.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2TS8E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	enoyl-CoA hydratase	fadJ	-	1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
CMS1_k127_2221803_10	876044.IMCC3088_687	3.456e-41	161.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_4,TetR_N
CMS1_k127_2221803_2	1123059.KB823011_gene1578	5.519e-236	741.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,2TRV6@28211|Alphaproteobacteria,440YZ@69657|Hyphomonadaceae	28211|Alphaproteobacteria	I	Carboxyl transferase domain	MA20_22955	-	6.4.1.5	ko:K13778	ko00281,map00281	-	R03494	RC00367,RC00942	ko00000,ko00001,ko01000	-	-	-	Carboxyl_trans
CMS1_k127_2269764_0	1545915.JROG01000003_gene1099	3.851e-318	984.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,2TRBP@28211|Alphaproteobacteria,2K167@204457|Sphingomonadales	204457|Sphingomonadales	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
CMS1_k127_2269764_2	579138.Zymop_0527	4.954e-41	158.0	COG0593@1|root,COG0593@2|Bacteria,1N4PG@1224|Proteobacteria,2U96K@28211|Alphaproteobacteria,2K4AT@204457|Sphingomonadales	204457|Sphingomonadales	L	ATPase involved in DNA replication	-	-	-	-	-	-	-	-	-	-	-	-	Bac_DnaA
CMS1_k127_2269764_1	1123270.ATUR01000005_gene449	1.472e-129	427.0	COG3249@1|root,COG3249@2|Bacteria,1R81G@1224|Proteobacteria,2U1EP@28211|Alphaproteobacteria,2K0TT@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2284470_0	1088721.NSU_3750	1.085e-126	408.0	COG0426@1|root,COG0426@2|Bacteria,1MXIE@1224|Proteobacteria,2U3GM@28211|Alphaproteobacteria,2KA6Y@204457|Sphingomonadales	204457|Sphingomonadales	C	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2284470_1	452662.SJA_C2-00440	1.929e-117	382.0	COG5588@1|root,COG5588@2|Bacteria,1RGIE@1224|Proteobacteria,2U11D@28211|Alphaproteobacteria,2K962@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF1326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1326
CMS1_k127_2284470_2	46429.BV95_04139	1.592e-88	299.0	COG5486@1|root,COG5486@2|Bacteria,1NFSK@1224|Proteobacteria,2U4IW@28211|Alphaproteobacteria,2K99T@204457|Sphingomonadales	204457|Sphingomonadales	S	Predicted metal-binding integral membrane protein (DUF2182)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2182
CMS1_k127_2284470_5	1335760.ASTG01000001_gene3000	8.624e-43	157.0	2C82G@1|root,32RK9@2|Bacteria,1MZV5@1224|Proteobacteria,2UCEY@28211|Alphaproteobacteria,2K7ZX@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
CMS1_k127_2284470_7	1280952.HJA_01205	2.189e-18	88.0	2CCNX@1|root,32RW4@2|Bacteria,1N3P1@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2284470_6	279238.Saro_3160	5.442e-36	144.0	COG2335@1|root,COG2335@2|Bacteria,1NG52@1224|Proteobacteria,2UFGF@28211|Alphaproteobacteria,2K7MI@204457|Sphingomonadales	204457|Sphingomonadales	M	Four repeated domains in the Fasciclin I family of proteins, present in many other contexts.	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
CMS1_k127_2284470_4	279238.Saro_3159	1.517e-67	242.0	29ZIU@1|root,30MJ0@2|Bacteria,1RF6K@1224|Proteobacteria,2U8DV@28211|Alphaproteobacteria,2K50U@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2284470_3	1209072.ALBT01000052_gene636	7.857e-87	295.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1FGJ5@10|Cellvibrio	1236|Gammaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GGDEF,PAS,PAS_3,PAS_8,PAS_9
CMS1_k127_2307190_4	1248760.ANFZ01000008_gene1584	1.908e-148	479.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,2TT2C@28211|Alphaproteobacteria,2K1HK@204457|Sphingomonadales	204457|Sphingomonadales	FP	exopolyphosphatase	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
CMS1_k127_2307190_6	1248917.ANFX01000006_gene82	3.805e-84	287.0	COG2197@1|root,COG2197@2|Bacteria,1R6UF@1224|Proteobacteria,2TU0V@28211|Alphaproteobacteria,2K2AM@204457|Sphingomonadales	204457|Sphingomonadales	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
CMS1_k127_2307190_1	383381.EH30_15720	5.79e-275	870.0	COG4774@1|root,COG4774@2|Bacteria,1NMCN@1224|Proteobacteria,2TVPT@28211|Alphaproteobacteria,2K2IS@204457|Sphingomonadales	204457|Sphingomonadales	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
CMS1_k127_2307190_10	1122214.AQWH01000026_gene4832	3.264e-27	117.0	COG5517@1|root,COG5517@2|Bacteria,1R9S1@1224|Proteobacteria,2VGRH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
CMS1_k127_2307190_9	1248917.ANFX01000032_gene866	1.633e-57	205.0	COG5517@1|root,COG5517@2|Bacteria,1N622@1224|Proteobacteria,2UHQF@28211|Alphaproteobacteria,2KE5P@204457|Sphingomonadales	204457|Sphingomonadales	Q	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
CMS1_k127_2307190_2	1248917.ANFX01000032_gene867	3.866e-225	706.0	COG4638@1|root,COG4638@2|Bacteria,1R56V@1224|Proteobacteria,2TTP0@28211|Alphaproteobacteria,2K21D@204457|Sphingomonadales	204457|Sphingomonadales	P	PFAM Rieske 2Fe-2S domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske,Ring_hydroxyl_A
CMS1_k127_2307190_0	391624.OIHEL45_19196	0.0	1082.0	COG0753@1|root,COG0753@2|Bacteria,1MUXZ@1224|Proteobacteria,2TSG9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	serves to protect cells from the toxic effects of hydrogen peroxide	katE	-	1.11.1.6	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	M00532	R00009,R00602,R02670	RC00034,RC00767,RC02141,RC02755	ko00000,ko00001,ko00002,ko01000	-	-	-	Catalase,Catalase-rel
CMS1_k127_2307190_3	383381.EH30_15655	1.178e-217	682.0	COG2124@1|root,COG2124@2|Bacteria,1MY5H@1224|Proteobacteria,2TTRR@28211|Alphaproteobacteria,2K2HH@204457|Sphingomonadales	204457|Sphingomonadales	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
CMS1_k127_2307190_5	1248917.ANFX01000019_gene2340	4.77e-101	332.0	COG2128@1|root,COG2128@2|Bacteria,1RI8R@1224|Proteobacteria,2UJBV@28211|Alphaproteobacteria,2K84A@204457|Sphingomonadales	204457|Sphingomonadales	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS1_k127_2307190_8	1248760.ANFZ01000002_gene3081	1.442e-66	234.0	2F69V@1|root,33YTJ@2|Bacteria,1MYST@1224|Proteobacteria,2UA2M@28211|Alphaproteobacteria,2K4MC@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2307190_7	1335760.ASTG01000018_gene3336	1.234e-82	276.0	COG3853@1|root,COG3853@2|Bacteria,1MY18@1224|Proteobacteria,2TU4T@28211|Alphaproteobacteria,2K07G@204457|Sphingomonadales	204457|Sphingomonadales	P	Toxic anion resistance	-	-	-	-	-	-	-	-	-	-	-	-	TelA
CMS1_k127_2346517_8	1122970.AUHC01000008_gene88	5.589e-08	60.0	29P04@1|root,309Y9@2|Bacteria,1NK7D@1224|Proteobacteria,2UNIE@28211|Alphaproteobacteria,2K6YM@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2346517_7	317655.Sala_0231	1.662e-15	78.0	2BMMB@1|root,32G6F@2|Bacteria,1NPK2@1224|Proteobacteria,2UKR9@28211|Alphaproteobacteria,2K7TJ@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2346517_4	627192.SLG_36470	2.098e-72	251.0	COG2932@1|root,COG2932@2|Bacteria,1N97M@1224|Proteobacteria,2UF88@28211|Alphaproteobacteria,2K4JZ@204457|Sphingomonadales	204457|Sphingomonadales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S24
CMS1_k127_2346517_1	237727.NAP1_07940	2.396e-121	391.0	COG0491@1|root,COG0491@2|Bacteria,1MUDN@1224|Proteobacteria,2TQJ9@28211|Alphaproteobacteria,2K19S@204457|Sphingomonadales	204457|Sphingomonadales	S	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS1_k127_2346517_3	1439940.BAY1663_02656	4.793e-79	268.0	COG3812@1|root,COG3812@2|Bacteria,1RGUV@1224|Proteobacteria,1S6J5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF1993)	-	-	-	ko:K09983	-	-	-	-	ko00000	-	-	-	DUF1993
CMS1_k127_2346517_5	1248760.ANFZ01000021_gene383	1.224e-46	171.0	COG3788@1|root,COG3788@2|Bacteria,1N0G5@1224|Proteobacteria,2UDEJ@28211|Alphaproteobacteria,2K642@204457|Sphingomonadales	204457|Sphingomonadales	S	relative of glutathione S-transferase, MAPEG superfamily	-	-	-	ko:K07136	-	-	-	-	ko00000	-	-	-	MAPEG
CMS1_k127_2346517_6	1174684.EBMC1_13091	5.574e-30	119.0	COG0333@1|root,COG0333@2|Bacteria,1PU3Y@1224|Proteobacteria,2UF54@28211|Alphaproteobacteria,2K6RY@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
CMS1_k127_2346517_0	1248760.ANFZ01000021_gene384	9.268e-156	497.0	COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,2TR53@28211|Alphaproteobacteria,2K0QU@204457|Sphingomonadales	204457|Sphingomonadales	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
CMS1_k127_2346517_2	1096930.L284_13210	5.16e-84	283.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,2TR60@28211|Alphaproteobacteria,2K1XQ@204457|Sphingomonadales	204457|Sphingomonadales	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
CMS1_k127_2368702_8	1248760.ANFZ01000011_gene280	3.309e-49	177.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,2TSTJ@28211|Alphaproteobacteria,2K1E1@204457|Sphingomonadales	204457|Sphingomonadales	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
CMS1_k127_2368702_5	1120705.FG95_01456	1.337e-91	304.0	COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,2U5E5@28211|Alphaproteobacteria,2K0SN@204457|Sphingomonadales	204457|Sphingomonadales	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
CMS1_k127_2368702_4	1123270.ATUR01000005_gene544	4.495e-104	343.0	COG0625@1|root,COG0625@2|Bacteria,1PHM1@1224|Proteobacteria,2TTQZ@28211|Alphaproteobacteria,2K0C9@204457|Sphingomonadales	204457|Sphingomonadales	O	Glutathione S-transferase	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_2,GST_N_2,GST_N_3
CMS1_k127_2368702_1	1096930.L284_08085	3.124e-172	548.0	COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,2TT0J@28211|Alphaproteobacteria,2K0C3@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls	dapE	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
CMS1_k127_2368702_2	1265313.HRUBRA_02368	1.497e-165	534.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,1RQRP@1236|Gammaproteobacteria,1J8WE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG1228 Imidazolonepropionase and related amidohydrolases	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
CMS1_k127_2368702_9	1123270.ATUR01000005_gene547	1.962e-42	164.0	COG2840@1|root,COG2840@2|Bacteria,1RH34@1224|Proteobacteria,2UCM1@28211|Alphaproteobacteria,2K652@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Smr
CMS1_k127_2368702_3	1114964.L485_06075	2.753e-145	474.0	COG2821@1|root,COG2821@2|Bacteria,1MXD4@1224|Proteobacteria,2TS5S@28211|Alphaproteobacteria,2K0IG@204457|Sphingomonadales	204457|Sphingomonadales	M	membrane-bound lytic murein transglycosylase	mltA	-	-	ko:K08304	-	-	-	-	ko00000,ko01000,ko01011	-	GH102	-	3D,MltA
CMS1_k127_2368702_6	1545915.JROG01000007_gene3168	8.862e-81	275.0	COG4395@1|root,COG4395@2|Bacteria,1NCIX@1224|Proteobacteria,2TTDQ@28211|Alphaproteobacteria,2K0UG@204457|Sphingomonadales	204457|Sphingomonadales	S	import inner membrane translocase, subunit Tim44	-	-	-	-	-	-	-	-	-	-	-	-	Tim44
CMS1_k127_2368702_7	1123270.ATUR01000005_gene550	1.037e-63	223.0	COG1952@1|root,COG1952@2|Bacteria,1RI75@1224|Proteobacteria,2UBTB@28211|Alphaproteobacteria,2K4QA@204457|Sphingomonadales	204457|Sphingomonadales	U	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA	secB	-	-	ko:K03071	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03110	3.A.5	-	-	SecB
CMS1_k127_2368702_0	1120705.FG95_00548	1.117e-181	579.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,2TS44@28211|Alphaproteobacteria,2K03M@204457|Sphingomonadales	204457|Sphingomonadales	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
CMS1_k127_2369932_1	1545915.JROG01000011_gene42	2.224e-88	297.0	COG0491@1|root,COG0491@2|Bacteria,1MUXF@1224|Proteobacteria,2TSYY@28211|Alphaproteobacteria,2K1NF@204457|Sphingomonadales	204457|Sphingomonadales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS1_k127_2369932_0	279238.Saro_3307	2.321e-122	406.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,2TUEW@28211|Alphaproteobacteria,2K3DH@204457|Sphingomonadales	204457|Sphingomonadales	EGP	Major Facilitator Superfamily	-	-	-	ko:K08151	-	M00668	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75	-	-	MFS_1,Sugar_tr
CMS1_k127_2369932_2	1545915.JROG01000008_gene3532	2.156e-65	234.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,2K001@204457|Sphingomonadales	204457|Sphingomonadales	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
CMS1_k127_238191_0	1248760.ANFZ01000021_gene407	0.0	1086.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,2TQZU@28211|Alphaproteobacteria,2JZX4@204457|Sphingomonadales	204457|Sphingomonadales	F	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
CMS1_k127_238191_6	317655.Sala_0986	5.318e-79	265.0	COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,2U5JU@28211|Alphaproteobacteria,2K439@204457|Sphingomonadales	204457|Sphingomonadales	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
CMS1_k127_238191_8	1207055.C100_07890	1.883e-61	221.0	COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,2TSJG@28211|Alphaproteobacteria,2K57C@204457|Sphingomonadales	204457|Sphingomonadales	S	membrane protein (homolog of Drosophila rhomboid)	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
CMS1_k127_238191_12	279238.Saro_2228	1.081e-30	122.0	COG0483@1|root,COG0483@2|Bacteria,1N7D7@1224|Proteobacteria,2UF6T@28211|Alphaproteobacteria,2K5WG@204457|Sphingomonadales	204457|Sphingomonadales	G	Domain of unknown function (DUF4170)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4170
CMS1_k127_238191_15	629773.AORY01000012_gene883	1.274e-11	72.0	28M97@1|root,2ZAN6@2|Bacteria,1P8DS@1224|Proteobacteria,2UXPS@28211|Alphaproteobacteria,2K5VF@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_238191_14	13690.CP98_03340	3.196e-27	118.0	2E966@1|root,333EU@2|Bacteria,1QUU3@1224|Proteobacteria,2TW7P@28211|Alphaproteobacteria,2KECQ@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_238191_1	13690.CP98_03339	8.804e-230	717.0	COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,2TR04@28211|Alphaproteobacteria,2K00W@204457|Sphingomonadales	204457|Sphingomonadales	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
CMS1_k127_238191_11	1545915.JROG01000003_gene1435	3.865e-35	138.0	COG2919@1|root,COG2919@2|Bacteria,1NGSW@1224|Proteobacteria,2UJYE@28211|Alphaproteobacteria,2K7B8@204457|Sphingomonadales	204457|Sphingomonadales	D	Septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
CMS1_k127_238191_4	745310.G432_13095	1.244e-174	554.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,2TRSS@28211|Alphaproteobacteria,2K0VG@204457|Sphingomonadales	204457|Sphingomonadales	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
CMS1_k127_238191_3	1123269.NX02_15375	1.111e-222	701.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,2TRMR@28211|Alphaproteobacteria,2JZYC@204457|Sphingomonadales	204457|Sphingomonadales	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhB	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl,Transket_pyr,Transketolase_C
CMS1_k127_238191_7	13690.CP98_03335	1.753e-64	229.0	COG4961@1|root,COG4961@2|Bacteria,1N654@1224|Proteobacteria,2UACZ@28211|Alphaproteobacteria,2K5UU@204457|Sphingomonadales	204457|Sphingomonadales	U	PFAM TadE family protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
CMS1_k127_238191_10	13690.CP98_03334	5.065e-43	166.0	COG4961@1|root,COG4961@2|Bacteria,1N0M1@1224|Proteobacteria,2UCUG@28211|Alphaproteobacteria,2K5JC@204457|Sphingomonadales	204457|Sphingomonadales	U	Flp pilus assembly protein TadG	-	-	-	-	-	-	-	-	-	-	-	-	TadE
CMS1_k127_238191_5	1207055.C100_07830	2.971e-140	472.0	COG2304@1|root,COG2304@2|Bacteria,1QUU2@1224|Proteobacteria,2TW7N@28211|Alphaproteobacteria,2KECP@204457|Sphingomonadales	204457|Sphingomonadales	S	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	Tad
CMS1_k127_238191_9	1537715.JQFJ01000002_gene324	7.722e-48	177.0	28ZT0@1|root,2ZMHP@2|Bacteria,1N2NU@1224|Proteobacteria,2UCQ1@28211|Alphaproteobacteria,2K5YM@204457|Sphingomonadales	204457|Sphingomonadales	S	EF hand	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_5
CMS1_k127_238191_2	1545915.JROG01000003_gene1427	3.015e-226	707.0	COG1206@1|root,COG1206@2|Bacteria,1MWNQ@1224|Proteobacteria,2TR6M@28211|Alphaproteobacteria,2K17V@204457|Sphingomonadales	204457|Sphingomonadales	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	trmFO	-	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
CMS1_k127_2392954_1	1123270.ATUR01000003_gene702	3.791e-82	275.0	COG0019@1|root,COG0019@2|Bacteria,1MW3T@1224|Proteobacteria,2TVR1@28211|Alphaproteobacteria,2K0YP@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the Orn Lys Arg decarboxylase class-II family. NspC subfamily	-	-	4.1.1.96	ko:K13747	ko00330,ko01100,map00330,map01100	-	R09081,R09082	RC00299	ko00000,ko00001,ko01000	-	-	-	Orn_DAP_Arg_deC
CMS1_k127_2392954_0	279238.Saro_1794	3.863e-176	559.0	COG0019@1|root,COG0019@2|Bacteria,1MZ7Y@1224|Proteobacteria,2TSKB@28211|Alphaproteobacteria,2K02Y@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the Orn Lys Arg decarboxylase class-II family	speF	-	4.1.1.17	ko:K01581	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	M00134	R00670	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
CMS1_k127_2392954_2	1545915.JROG01000003_gene1070	2.115e-53	190.0	COG5331@1|root,COG5331@2|Bacteria,1RI4N@1224|Proteobacteria,2UA3C@28211|Alphaproteobacteria,2K5DV@204457|Sphingomonadales	204457|Sphingomonadales	S	MAPEG family	-	-	-	-	-	-	-	-	-	-	-	-	MAPEG
CMS1_k127_2417331_5	1161401.ASJA01000001_gene475	3.291e-25	106.0	COG1960@1|root,COG1960@2|Bacteria,1MUBH@1224|Proteobacteria,2TVBB@28211|Alphaproteobacteria,43WMP@69657|Hyphomonadaceae	28211|Alphaproteobacteria	I	acyl-CoA dehydrogenase	MA20_22775	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS1_k127_2417331_6	1123255.JHYS01000013_gene15	3.726e-25	109.0	COG4319@1|root,COG4319@2|Bacteria,1QXYE@1224|Proteobacteria,2WHS9@28216|Betaproteobacteria,4AI06@80864|Comamonadaceae	28216|Betaproteobacteria	S	Nuclear transport factor 2 (NTF2) domain	-	-	5.3.3.1	ko:K01822	ko00140,ko00984,ko01100,ko01120,map00140,map00984,map01100,map01120	M00107,M00110	R01837,R02216,R02499,R02840,R03327,R04163,R04678,R04849,R09955	RC00146,RC00762	ko00000,ko00001,ko00002,ko01000	-	-	-	SnoaL_2
CMS1_k127_2417331_2	383381.EH30_15740	2.87e-80	275.0	COG1028@1|root,COG1028@2|Bacteria,1RGQG@1224|Proteobacteria,2VFFQ@28211|Alphaproteobacteria,2K4ZF@204457|Sphingomonadales	204457|Sphingomonadales	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS1_k127_2417331_4	279238.Saro_3555	2.944e-33	133.0	COG1545@1|root,COG1545@2|Bacteria,1N61A@1224|Proteobacteria,2UCRM@28211|Alphaproteobacteria,2K69M@204457|Sphingomonadales	204457|Sphingomonadales	S	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	OB_aCoA_assoc
CMS1_k127_2417331_1	685035.ADAE01000003_gene2806	1.179e-191	608.0	COG0183@1|root,COG0183@2|Bacteria,1R5AW@1224|Proteobacteria,2U1UK@28211|Alphaproteobacteria,2K1A4@204457|Sphingomonadales	204457|Sphingomonadales	I	Acetyl-CoA acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C
CMS1_k127_2417331_0	46429.BV95_03755	5.268e-196	623.0	COG1960@1|root,COG1960@2|Bacteria,1MU2V@1224|Proteobacteria,2TSK3@28211|Alphaproteobacteria,2K09W@204457|Sphingomonadales	204457|Sphingomonadales	I	acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS1_k127_2417331_3	1220535.IMCC14465_09450	2.151e-40	152.0	COG2130@1|root,COG2130@2|Bacteria,1MUC2@1224|Proteobacteria,2TQYM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	NADP-dependent oxidoreductase	-	-	-	ko:K07119	-	-	-	-	ko00000	-	-	-	ADH_N_2,ADH_zinc_N
CMS1_k127_2490266_0	1545915.JROG01000004_gene2013	1.022e-189	595.0	COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,2TRPG@28211|Alphaproteobacteria,2K13Q@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
CMS1_k127_2490266_5	1120705.FG95_01930	6.269e-58	211.0	2919Q@1|root,2ZNWS@2|Bacteria,1NAF5@1224|Proteobacteria,2UBP7@28211|Alphaproteobacteria,2K4SN@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2490266_3	1121930.AQXG01000006_gene853	3.02e-97	330.0	COG3055@1|root,COG3055@2|Bacteria,4NWEV@976|Bacteroidetes,1IXYN@117747|Sphingobacteriia	976|Bacteroidetes	S	Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_6
CMS1_k127_2490266_7	1449076.JOOE01000002_gene1288	2.11e-50	194.0	2BX8M@1|root,31H0R@2|Bacteria,1MYMI@1224|Proteobacteria,2UB1B@28211|Alphaproteobacteria,2K27Q@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF4230)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4230
CMS1_k127_2490266_2	1248760.ANFZ01000018_gene570	3.138e-139	448.0	COG0491@1|root,COG0491@2|Bacteria,1MVC3@1224|Proteobacteria,2TUAZ@28211|Alphaproteobacteria,2K18T@204457|Sphingomonadales	204457|Sphingomonadales	S	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS1_k127_2490266_4	1545915.JROG01000004_gene2010	4.987e-87	310.0	COG4219@1|root,COG4219@2|Bacteria,1R3YH@1224|Proteobacteria,2U67Y@28211|Alphaproteobacteria,2K1JQ@204457|Sphingomonadales	204457|Sphingomonadales	KT	Antirepressor regulating drug resistance	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
CMS1_k127_2490266_8	627192.SLG_16440	8.486e-45	166.0	COG3682@1|root,COG3682@2|Bacteria,1RH6Y@1224|Proteobacteria,2U9MX@28211|Alphaproteobacteria,2KCHB@204457|Sphingomonadales	204457|Sphingomonadales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
CMS1_k127_2490266_6	291985.CCSI01000004_gene639	2.791e-51	184.0	COG0278@1|root,COG0278@2|Bacteria,1MZ4V@1224|Proteobacteria,2U9QB@28211|Alphaproteobacteria,2K55Y@204457|Sphingomonadales	204457|Sphingomonadales	O	Belongs to the glutaredoxin family. Monothiol subfamily	grxD	-	-	ko:K07390	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Glutaredoxin
CMS1_k127_2490266_11	279238.Saro_2520	1.099e-28	118.0	COG0271@1|root,COG0271@2|Bacteria,1R3MM@1224|Proteobacteria,2UBUW@28211|Alphaproteobacteria,2K5YQ@204457|Sphingomonadales	204457|Sphingomonadales	T	Belongs to the BolA IbaG family	-	-	-	-	-	-	-	-	-	-	-	-	BolA
CMS1_k127_2490266_9	1545915.JROG01000004_gene2282	1.823e-43	162.0	COG5467@1|root,COG5467@2|Bacteria,1MZRN@1224|Proteobacteria,2UC1G@28211|Alphaproteobacteria,2K533@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF1476)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1476
CMS1_k127_2490266_1	745310.G432_17345	4.542e-160	515.0	COG0604@1|root,COG0604@2|Bacteria,1MWRK@1224|Proteobacteria,2TQMF@28211|Alphaproteobacteria,2K1HA@204457|Sphingomonadales	204457|Sphingomonadales	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_2490266_10	1545915.JROG01000004_gene2280	5.871e-35	135.0	COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,2TRRS@28211|Alphaproteobacteria,2JZWQ@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
CMS1_k127_2505819_0	1123269.NX02_08185	1.289e-243	789.0	COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,2TR45@28211|Alphaproteobacteria,2K0C4@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
CMS1_k127_2505819_1	1219045.BV98_001108	1.466e-199	644.0	COG0729@1|root,COG0729@2|Bacteria,1MUKM@1224|Proteobacteria,2TRWD@28211|Alphaproteobacteria,2JZVN@204457|Sphingomonadales	204457|Sphingomonadales	M	COG0729 Outer membrane protein	-	-	-	ko:K07278	-	-	-	-	ko00000,ko02000	1.B.33.2.4	-	-	Bac_surface_Ag,POTRA
CMS1_k127_2505819_3	317655.Sala_1326	1.957e-26	116.0	COG4719@1|root,COG4719@2|Bacteria,1N2CR@1224|Proteobacteria,2UE4C@28211|Alphaproteobacteria,2KE4M@204457|Sphingomonadales	204457|Sphingomonadales	S	TIGRFAM conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
CMS1_k127_2505819_2	1305735.JAFT01000005_gene1934	2.094e-68	235.0	COG3214@1|root,COG3214@2|Bacteria,1N40B@1224|Proteobacteria,2TT7U@28211|Alphaproteobacteria,2PD9E@252301|Oceanicola	28211|Alphaproteobacteria	S	Winged helix DNA-binding domain	-	-	-	ko:K09927	-	-	-	-	ko00000	-	-	-	HTH_42
CMS1_k127_2573293_15	1120705.FG95_00405	7.603e-14	75.0	COG0596@1|root,COG0596@2|Bacteria,1QVQ5@1224|Proteobacteria,2UEVX@28211|Alphaproteobacteria,2KCXE@204457|Sphingomonadales	204457|Sphingomonadales	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CMS1_k127_2573293_6	1174684.EBMC1_00475	2.097e-96	323.0	COG2267@1|root,COG2267@2|Bacteria,1MWF5@1224|Proteobacteria,2VFDU@28211|Alphaproteobacteria,2K48Y@204457|Sphingomonadales	204457|Sphingomonadales	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
CMS1_k127_2573293_3	1502850.FG91_01684	6.86e-187	595.0	COG1752@1|root,COG1752@2|Bacteria,1N5SK@1224|Proteobacteria,2UP09@28211|Alphaproteobacteria,2K9EB@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF3336)	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	DUF3336,Patatin
CMS1_k127_2573293_2	1120705.FG95_00408	9.874e-196	623.0	COG1020@1|root,COG1020@2|Bacteria,1N7HY@1224|Proteobacteria,2TRZV@28211|Alphaproteobacteria,2K46G@204457|Sphingomonadales	204457|Sphingomonadales	Q	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
CMS1_k127_2573293_0	317655.Sala_0194	1.501e-276	871.0	COG2937@1|root,COG2937@2|Bacteria,1MWZ6@1224|Proteobacteria	1224|Proteobacteria	I	Belongs to the GPAT DAPAT family	-	-	2.3.1.15	ko:K00631	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
CMS1_k127_2573293_1	1120705.FG95_00410	5.49e-232	731.0	COG0204@1|root,COG0560@1|root,COG0204@2|Bacteria,COG0560@2|Bacteria,1MY51@1224|Proteobacteria,2UI5H@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Phosphate acyltransferases	-	-	2.3.1.51,3.1.3.3	ko:K15781	-	-	-	-	ko00000,ko01000	-	-	-	Acyltransferase,HAD
CMS1_k127_2573293_8	1537715.JQFJ01000002_gene2457	1.306e-60	220.0	28W2F@1|root,2ZI3D@2|Bacteria,1MYFI@1224|Proteobacteria,2UAR9@28211|Alphaproteobacteria,2K535@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2573293_5	1120705.FG95_03882	6.034e-113	379.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,2TT0E@28211|Alphaproteobacteria,2K188@204457|Sphingomonadales	204457|Sphingomonadales	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
CMS1_k127_2573293_9	1537715.JQFJ01000002_gene2455	2.312e-60	212.0	COG1595@1|root,COG1595@2|Bacteria,1MZMC@1224|Proteobacteria,2U9FD@28211|Alphaproteobacteria,2K4SI@204457|Sphingomonadales	204457|Sphingomonadales	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_2573293_10	1537715.JQFJ01000002_gene2454	1.215e-54	200.0	COG5662@1|root,COG5662@2|Bacteria,1RK96@1224|Proteobacteria,2U9MN@28211|Alphaproteobacteria,2K553@204457|Sphingomonadales	204457|Sphingomonadales	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2573293_12	1537715.JQFJ01000002_gene1738	1.303e-27	115.0	2AM1H@1|root,31BVB@2|Bacteria,1N4R6@1224|Proteobacteria,2UERF@28211|Alphaproteobacteria,2K7J0@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2573293_4	1545915.JROG01000007_gene3034	6.867e-124	418.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2U05U@28211|Alphaproteobacteria,2K1IQ@204457|Sphingomonadales	204457|Sphingomonadales	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
CMS1_k127_2573293_14	1395516.PMO01_19030	1.21e-16	84.0	COG0784@1|root,COG0784@2|Bacteria,1N70P@1224|Proteobacteria	1224|Proteobacteria	T	Response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS1_k127_2573293_7	1247963.JPHU01000003_gene1200	9.024e-87	303.0	COG3920@1|root,COG5000@1|root,COG3920@2|Bacteria,COG5000@2|Bacteria,1NU8D@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HWE_HK,PAS_3,PAS_4
CMS1_k127_2573293_13	1282361.ABAC402_15150	1.123e-20	94.0	COG3237@1|root,COG3237@2|Bacteria,1N6X4@1224|Proteobacteria,2UF5Q@28211|Alphaproteobacteria,2KJEK@204458|Caulobacterales	204458|Caulobacterales	S	Belongs to the UPF0337 (CsbD) family	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
CMS1_k127_2573293_11	1112212.JH584235_gene3517	2.771e-41	154.0	COG3785@1|root,COG3785@2|Bacteria,1RHM7@1224|Proteobacteria,2U9MS@28211|Alphaproteobacteria,2K54K@204457|Sphingomonadales	204457|Sphingomonadales	S	DNA-binding protein	-	-	-	ko:K11940	-	-	-	-	ko00000,ko03036	-	-	-	YccV-like
CMS1_k127_2586360_5	1248760.ANFZ01000018_gene552	2.217e-46	173.0	COG3791@1|root,COG3791@2|Bacteria,1N0W7@1224|Proteobacteria,2UC83@28211|Alphaproteobacteria,2K5XY@204457|Sphingomonadales	204457|Sphingomonadales	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
CMS1_k127_2586360_2	1234595.C725_1661	6.581e-98	326.0	COG1801@1|root,COG1801@2|Bacteria,1MU7F@1224|Proteobacteria,2TT1D@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function DUF72	MA20_09500	-	-	-	-	-	-	-	-	-	-	-	DUF72
CMS1_k127_2586360_0	1479239.JQMU01000001_gene487	1.687e-183	581.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,2TU94@28211|Alphaproteobacteria,2K2VX@204457|Sphingomonadales	204457|Sphingomonadales	I	COG0332 3-oxoacyl- acyl-carrier-protein synthase III	-	-	2.3.1.207	ko:K16872	-	-	-	-	ko00000,ko01000	-	-	-	ACP_syn_III,ACP_syn_III_C
CMS1_k127_2586360_1	392499.Swit_3206	5.147e-122	396.0	COG0692@1|root,COG0692@2|Bacteria,1MV80@1224|Proteobacteria,2U1VI@28211|Alphaproteobacteria,2K0CQ@204457|Sphingomonadales	204457|Sphingomonadales	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	-	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
CMS1_k127_2586360_4	1502850.FG91_03489	1.304e-77	272.0	COG2267@1|root,COG2267@2|Bacteria,1RATF@1224|Proteobacteria,2TTCT@28211|Alphaproteobacteria,2K1SM@204457|Sphingomonadales	204457|Sphingomonadales	I	Alpha beta hydrolase	-	-	-	ko:K18092	ko00642,ko01100,ko01120,ko01220,map00642,map01100,map01120,map01220	-	R05366	RC00752,RC00753	br01602,ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS1_k127_2586360_3	1030157.AFMP01000032_gene493	8.166e-87	292.0	COG1187@1|root,COG1187@2|Bacteria,1R9VV@1224|Proteobacteria,2U5H3@28211|Alphaproteobacteria,2K0BZ@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the pseudouridine synthase RsuA family	rluE	-	5.4.99.20	ko:K06181	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
CMS1_k127_2609257_8	314266.SKA58_09581	3.706e-20	96.0	2EGH8@1|root,33A9B@2|Bacteria,1NF4H@1224|Proteobacteria,2UI1B@28211|Alphaproteobacteria,2KCHW@204457|Sphingomonadales	204457|Sphingomonadales	S	Type II secretion system (T2SS), protein N	-	-	-	ko:K02463	ko05111,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSN
CMS1_k127_2609257_5	1248917.ANFX01000014_gene1353	3.47e-41	158.0	COG0526@1|root,COG0526@2|Bacteria,1N81A@1224|Proteobacteria,2UGCI@28211|Alphaproteobacteria,2K7HK@204457|Sphingomonadales	204457|Sphingomonadales	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_7
CMS1_k127_2609257_2	1342301.JASD01000008_gene2204	1.83e-157	499.0	COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,2TTPH@28211|Alphaproteobacteria,3ZYPI@60136|Sulfitobacter	28211|Alphaproteobacteria	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
CMS1_k127_2609257_0	1545915.JROG01000004_gene2350	1.156e-220	689.0	COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,2TQSI@28211|Alphaproteobacteria,2K1FA@204457|Sphingomonadales	204457|Sphingomonadales	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
CMS1_k127_2609257_4	1545915.JROG01000004_gene2348	2.036e-65	233.0	COG1028@1|root,COG1028@2|Bacteria,1RHYX@1224|Proteobacteria,2TUR9@28211|Alphaproteobacteria,2K4MT@204457|Sphingomonadales	204457|Sphingomonadales	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS1_k127_2609257_3	314225.ELI_10330	1.563e-128	420.0	COG1446@1|root,COG1446@2|Bacteria,1MWFC@1224|Proteobacteria,2TU8K@28211|Alphaproteobacteria,2K0JU@204457|Sphingomonadales	204457|Sphingomonadales	E	Asparaginase	-	-	3.4.19.5	ko:K13051	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Asparaginase_2
CMS1_k127_2609257_9	1121022.ABENE_10855	9.774e-08	59.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2TV11@28211|Alphaproteobacteria,2KEYK@204458|Caulobacterales	204458|Caulobacterales	J	PFAM Amidase	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
CMS1_k127_2609257_6	685035.ADAE01000004_gene1952	1.95e-39	153.0	2E3B5@1|root,32YAP@2|Bacteria,1N7KQ@1224|Proteobacteria,2UHG1@28211|Alphaproteobacteria,2K43M@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF2721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2721
CMS1_k127_2609257_7	1470591.BW41_01827	8.864e-23	112.0	28JZK@1|root,2Z9PJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2609257_1	1120705.FG95_01364	3.439e-216	676.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,2TTB9@28211|Alphaproteobacteria,2K212@204457|Sphingomonadales	204457|Sphingomonadales	I	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
CMS1_k127_267197_6	1090319.KE386571_gene536	2.423e-160	516.0	COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,2TTQC@28211|Alphaproteobacteria,2K1YR@204457|Sphingomonadales	204457|Sphingomonadales	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.24	ko:K06179	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
CMS1_k127_267197_17	1123269.NX02_26470	7.688e-42	156.0	COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,2UBUP@28211|Alphaproteobacteria,2K5ZR@204457|Sphingomonadales	204457|Sphingomonadales	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
CMS1_k127_267197_18	1122612.AUBA01000019_gene3001	1.096e-28	118.0	COG4321@1|root,COG4321@2|Bacteria	2|Bacteria	O	Ribbon-helix-helix domain	MA20_02235	-	-	-	-	-	-	-	-	-	-	-	RHH_4
CMS1_k127_267197_7	317655.Sala_2253	9.051e-143	459.0	COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,2TSMS@28211|Alphaproteobacteria,2K0NQ@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
CMS1_k127_267197_0	1123270.ATUR01000007_gene1367	5.943e-275	865.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2TQVK@28211|Alphaproteobacteria,2K25R@204457|Sphingomonadales	204457|Sphingomonadales	C	aerobic-type carbon monoxide dehydrogenase, large subunit CoxL	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
CMS1_k127_267197_16	1123270.ATUR01000007_gene1366	9.066e-52	186.0	COG1832@1|root,COG1832@2|Bacteria,1N03D@1224|Proteobacteria,2TUIY@28211|Alphaproteobacteria,2K4FQ@204457|Sphingomonadales	204457|Sphingomonadales	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
CMS1_k127_267197_8	1545915.JROG01000008_gene3412	2.897e-137	443.0	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,2TRDM@28211|Alphaproteobacteria,2K1RH@204457|Sphingomonadales	204457|Sphingomonadales	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	ParA
CMS1_k127_267197_9	1545915.JROG01000008_gene3413	2.362e-136	444.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,2TRTP@28211|Alphaproteobacteria,2K20N@204457|Sphingomonadales	204457|Sphingomonadales	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
CMS1_k127_267197_11	1331060.RLDS_13275	5.311e-129	419.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,2TRP4@28211|Alphaproteobacteria,2K1HR@204457|Sphingomonadales	204457|Sphingomonadales	O	HflC and HflK could regulate a protease	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
CMS1_k127_267197_3	1248760.ANFZ01000011_gene224	1.598e-203	646.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2TQPZ@28211|Alphaproteobacteria,2K08H@204457|Sphingomonadales	204457|Sphingomonadales	M	Belongs to the peptidase S1C family	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
CMS1_k127_267197_1	237727.NAP1_14143	3.535e-271	841.0	COG0433@1|root,COG0433@2|Bacteria,1MU59@1224|Proteobacteria,2TRU8@28211|Alphaproteobacteria,2JZYW@204457|Sphingomonadales	204457|Sphingomonadales	S	Bacterial protein of unknown function (DUF853)	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853
CMS1_k127_267197_15	1545915.JROG01000003_gene1241	5.622e-63	218.0	COG0824@1|root,COG0824@2|Bacteria,1RHB1@1224|Proteobacteria,2UATC@28211|Alphaproteobacteria,2K4SF@204457|Sphingomonadales	204457|Sphingomonadales	S	thioesterase	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,Acyl-ACP_TE
CMS1_k127_267197_13	317655.Sala_3063	2.207e-88	292.0	COG0780@1|root,COG0780@2|Bacteria,1MW0M@1224|Proteobacteria,2U57X@28211|Alphaproteobacteria,2K3W2@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
CMS1_k127_267197_2	1123270.ATUR01000007_gene1356	6.344e-261	820.0	COG3046@1|root,COG3046@2|Bacteria,1MUHX@1224|Proteobacteria,2TQP6@28211|Alphaproteobacteria,2K23F@204457|Sphingomonadales	204457|Sphingomonadales	S	Deoxyribodipyrimidine photo-lyase	-	-	-	ko:K06876	-	-	-	-	ko00000	-	-	-	DPRP
CMS1_k127_267197_10	1545915.JROG01000003_gene1562	2.68e-136	439.0	COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,2TR9R@28211|Alphaproteobacteria,2K1GF@204457|Sphingomonadales	204457|Sphingomonadales	P	Catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds	sseA	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
CMS1_k127_267197_4	392499.Swit_3776	3.269e-168	536.0	COG0626@1|root,COG0626@2|Bacteria,1MU9E@1224|Proteobacteria,2TS8Z@28211|Alphaproteobacteria,2K0WB@204457|Sphingomonadales	204457|Sphingomonadales	E	cystathionine beta-lyase	metC	-	4.4.1.8	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
CMS1_k127_267197_5	1545915.JROG01000003_gene1564	1.557e-166	534.0	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,2TRKK@28211|Alphaproteobacteria,2K0A6@204457|Sphingomonadales	204457|Sphingomonadales	M	mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
CMS1_k127_267197_14	1219035.NT2_05_03140	4.99e-73	257.0	2C5U9@1|root,2Z9NJ@2|Bacteria,1RG51@1224|Proteobacteria,2U7E6@28211|Alphaproteobacteria,2KC9P@204457|Sphingomonadales	204457|Sphingomonadales	S	Bacterial protein of unknown function (Gcw_chp)	-	-	-	-	-	-	-	-	-	-	-	-	Gcw_chp
CMS1_k127_267197_12	745310.G432_09785	1.874e-95	319.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2TQP0@28211|Alphaproteobacteria,2K1VP@204457|Sphingomonadales	204457|Sphingomonadales	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K02032,ko:K13896	ko02010,ko02024,map02010,map02024	M00239,M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.21,3.A.1.5.24	-	-	ABC_tran,oligo_HPY
CMS1_k127_2684163_12	1545915.JROG01000004_gene2025	3.352e-24	106.0	COG3788@1|root,COG3788@2|Bacteria,1Q7CA@1224|Proteobacteria,2VDH4@28211|Alphaproteobacteria,2K5AS@204457|Sphingomonadales	204457|Sphingomonadales	S	MAPEG family	-	-	-	-	-	-	-	-	-	-	-	-	MAPEG
CMS1_k127_2684163_7	1123270.ATUR01000003_gene1110	1.151e-97	325.0	COG0476@1|root,COG0476@2|Bacteria,1MW7H@1224|Proteobacteria,2TRWY@28211|Alphaproteobacteria,2K1F9@204457|Sphingomonadales	204457|Sphingomonadales	H	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2	moeB	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
CMS1_k127_2684163_15	1112216.JH594425_gene155	5.265e-05	51.0	2AKPA@1|root,31BFY@2|Bacteria,1P48H@1224|Proteobacteria,2UW82@28211|Alphaproteobacteria,2K56W@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2684163_9	1123270.ATUR01000003_gene1109	1.183e-66	229.0	COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,2U7B5@28211|Alphaproteobacteria,2K4E7@204457|Sphingomonadales	204457|Sphingomonadales	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
CMS1_k127_2684163_4	1545915.JROG01000007_gene3174	3.683e-180	576.0	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,2TRN1@28211|Alphaproteobacteria,2K0N6@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
CMS1_k127_2684163_0	317655.Sala_3185	6.689e-250	780.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,2TS87@28211|Alphaproteobacteria,2K1BA@204457|Sphingomonadales	204457|Sphingomonadales	S	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis	ubiB	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
CMS1_k127_2684163_6	702113.PP1Y_AT33818	3.806e-113	371.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,2TRWR@28211|Alphaproteobacteria,2K080@204457|Sphingomonadales	204457|Sphingomonadales	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
CMS1_k127_2684163_5	1007104.SUS17_1345	1.675e-128	415.0	COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,2TS4C@28211|Alphaproteobacteria,2K2A5@204457|Sphingomonadales	204457|Sphingomonadales	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
CMS1_k127_2684163_11	1123270.ATUR01000005_gene555	3.596e-31	124.0	COG0268@1|root,COG0268@2|Bacteria,1MZ94@1224|Proteobacteria,2UC42@28211|Alphaproteobacteria,2K617@204457|Sphingomonadales	204457|Sphingomonadales	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
CMS1_k127_2684163_8	1248760.ANFZ01000006_gene2323	3.31e-73	252.0	2C0PG@1|root,330E3@2|Bacteria,1RA6M@1224|Proteobacteria,2U5UJ@28211|Alphaproteobacteria,2K3P1@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF4136)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4136
CMS1_k127_2684163_3	1123270.ATUR01000005_gene554	2.02e-188	601.0	COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,2TT03@28211|Alphaproteobacteria,2JZZ0@204457|Sphingomonadales	204457|Sphingomonadales	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
CMS1_k127_2684163_14	981223.AIED01000149_gene464	6.107e-06	49.0	2EJ6D@1|root,33CXK@2|Bacteria,1NHGW@1224|Proteobacteria,1SGZR@1236|Gammaproteobacteria,3NQBV@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2684163_10	1248760.ANFZ01000009_gene1241	8.481e-61	217.0	COG0526@1|root,COG0526@2|Bacteria,1MZ5J@1224|Proteobacteria,2TR0C@28211|Alphaproteobacteria,2K5QM@204457|Sphingomonadales	204457|Sphingomonadales	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
CMS1_k127_2684163_1	1114964.L485_15975	8.886e-228	714.0	COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,2TR4H@28211|Alphaproteobacteria,2K185@204457|Sphingomonadales	204457|Sphingomonadales	E	argininosuccinate lyase	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
CMS1_k127_2684163_13	1112216.JH594425_gene821	6.304e-19	89.0	293KA@1|root,2ZR29@2|Bacteria,1NKAC@1224|Proteobacteria,2UK1U@28211|Alphaproteobacteria,2K6TK@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2684163_2	1174684.EBMC1_00440	4.259e-205	644.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,2TQPB@28211|Alphaproteobacteria,2JZWD@204457|Sphingomonadales	204457|Sphingomonadales	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
CMS1_k127_2700296_3	760192.Halhy_5737	1.58e-25	108.0	COG0624@1|root,COG0624@2|Bacteria,4NEA7@976|Bacteroidetes,1IWTY@117747|Sphingobacteriia	976|Bacteroidetes	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
CMS1_k127_2700296_0	1096930.L284_04020	5.721e-101	334.0	COG1028@1|root,COG1028@2|Bacteria,1MW46@1224|Proteobacteria,2TUTU@28211|Alphaproteobacteria,2K1ME@204457|Sphingomonadales	204457|Sphingomonadales	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS1_k127_2700296_1	748247.AZKH_2298	1.846e-100	333.0	COG3828@1|root,COG3828@2|Bacteria,1QWCA@1224|Proteobacteria	1224|Proteobacteria	S	Protein conserved in bacteria	MA20_14010	-	-	ko:K09992	-	-	-	-	ko00000	-	-	-	ThuA
CMS1_k127_2700296_2	748247.AZKH_2297	5.569e-34	134.0	COG0346@1|root,COG0346@2|Bacteria,1MWHG@1224|Proteobacteria,2VJM7@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_4
CMS1_k127_2702006_0	1219035.NT2_02_02050	4.993e-153	486.0	COG2189@1|root,COG2189@2|Bacteria,1MX9M@1224|Proteobacteria,2TSW9@28211|Alphaproteobacteria,2K0RE@204457|Sphingomonadales	204457|Sphingomonadales	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.72	ko:K13581	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko02048	-	-	-	N6_N4_Mtase
CMS1_k127_2702006_1	1120792.JAFV01000001_gene403	1.849e-104	349.0	COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,2TSWD@28211|Alphaproteobacteria,36ZUT@31993|Methylocystaceae	28211|Alphaproteobacteria	I	Fatty acid desaturase	-	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
CMS1_k127_2702006_3	1120705.FG95_02868	2.472e-76	261.0	COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,2U73X@28211|Alphaproteobacteria,2K1EB@204457|Sphingomonadales	204457|Sphingomonadales	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
CMS1_k127_2702006_2	1090320.KB900605_gene1403	1.311e-102	342.0	COG0351@1|root,COG0351@2|Bacteria,1MU9J@1224|Proteobacteria,2TUKR@28211|Alphaproteobacteria,2K24Q@204457|Sphingomonadales	204457|Sphingomonadales	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase,Phos_pyr_kin
CMS1_k127_2702006_5	1502850.FG91_00158	3.887e-28	118.0	COG3813@1|root,COG3813@2|Bacteria,1N712@1224|Proteobacteria,2UFME@28211|Alphaproteobacteria,2K78J@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	ko:K09984	-	-	-	-	ko00000	-	-	-	DUF1272
CMS1_k127_2702006_4	291985.CCSI01000003_gene319	5.354e-55	194.0	COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,2TQWH@28211|Alphaproteobacteria,2JZV4@204457|Sphingomonadales	204457|Sphingomonadales	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
CMS1_k127_2704550_2	1120705.FG95_02865	8.344e-185	582.0	COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,2TQWH@28211|Alphaproteobacteria,2JZV4@204457|Sphingomonadales	204457|Sphingomonadales	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
CMS1_k127_2704550_5	1545915.JROG01000007_gene3043	1.948e-141	461.0	COG1301@1|root,COG1301@2|Bacteria,1MVID@1224|Proteobacteria,2TUR0@28211|Alphaproteobacteria,2K09V@204457|Sphingomonadales	204457|Sphingomonadales	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
CMS1_k127_2704550_3	1545915.JROG01000007_gene3044	2.629e-166	528.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,2TRHS@28211|Alphaproteobacteria,2K0VS@204457|Sphingomonadales	204457|Sphingomonadales	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS1_k127_2704550_4	1545915.JROG01000007_gene3059	9.299e-166	531.0	COG1228@1|root,COG1228@2|Bacteria,1MXQX@1224|Proteobacteria,2U1V8@28211|Alphaproteobacteria,2K2YY@204457|Sphingomonadales	204457|Sphingomonadales	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
CMS1_k127_2704550_1	1174684.EBMC1_08266	4.829e-224	711.0	COG1228@1|root,COG1228@2|Bacteria,1MXXR@1224|Proteobacteria,2TUMS@28211|Alphaproteobacteria,2K1BD@204457|Sphingomonadales	204457|Sphingomonadales	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
CMS1_k127_2704550_0	317655.Sala_0954	8.925e-256	797.0	COG3104@1|root,COG3104@2|Bacteria,1MW6W@1224|Proteobacteria,2U15C@28211|Alphaproteobacteria,2K05X@204457|Sphingomonadales	204457|Sphingomonadales	E	amino acid peptide transporter	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
CMS1_k127_2704550_6	1248760.ANFZ01000006_gene2468	4.666e-82	279.0	COG0778@1|root,COG0778@2|Bacteria,1PKUV@1224|Proteobacteria,2U5MZ@28211|Alphaproteobacteria,2K422@204457|Sphingomonadales	204457|Sphingomonadales	C	nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CMS1_k127_2704550_7	13690.CP98_01182	3.851e-44	162.0	COG1725@1|root,COG1725@2|Bacteria,1MZG9@1224|Proteobacteria,2UBQ4@28211|Alphaproteobacteria,2K632@204457|Sphingomonadales	204457|Sphingomonadales	K	Transcriptional regulator	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
CMS1_k127_2704550_8	1248760.ANFZ01000018_gene508	3.487e-34	141.0	COG0457@1|root,COG0457@2|Bacteria,1PDUB@1224|Proteobacteria,2TTYN@28211|Alphaproteobacteria,2K0P8@204457|Sphingomonadales	204457|Sphingomonadales	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_21
CMS1_k127_2704577_0	1545915.JROG01000008_gene3312	4.359e-291	908.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,2TQQ8@28211|Alphaproteobacteria,2K0HX@204457|Sphingomonadales	204457|Sphingomonadales	M	penicillin-binding protein	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
CMS1_k127_2704577_2	1192759.AKIB01000050_gene1039	2.613e-57	203.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,2U70T@28211|Alphaproteobacteria,2K4RU@204457|Sphingomonadales	204457|Sphingomonadales	O	Belongs to the MsrB Met sulfoxide reductase family	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
CMS1_k127_2704577_5	1174684.EBMC1_11825	1.927e-32	133.0	2AGZR@1|root,3178H@2|Bacteria,1NJBM@1224|Proteobacteria,2UJXF@28211|Alphaproteobacteria,2K8AT@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF4402)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4402
CMS1_k127_2704577_4	1550073.JROH01000008_gene1729	1.584e-49	196.0	COG1466@1|root,COG1466@2|Bacteria,1N7AB@1224|Proteobacteria,2UHPM@28211|Alphaproteobacteria,2K0ER@204457|Sphingomonadales	204457|Sphingomonadales	L	DNA polymerase III	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
CMS1_k127_2704577_3	1123270.ATUR01000004_gene1492	8.071e-54	194.0	COG5468@1|root,COG5468@2|Bacteria,1MXDR@1224|Proteobacteria,2UB6D@28211|Alphaproteobacteria,2KD8X@204457|Sphingomonadales	204457|Sphingomonadales	S	Lipopolysaccharide-assembly	-	-	-	ko:K03643	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptE
CMS1_k127_2704577_1	1007104.SUS17_2871	5.289e-174	550.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,2TQPK@28211|Alphaproteobacteria,2K0Q0@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
CMS1_k127_2747952_8	744979.R2A130_1102	8.863e-48	171.0	COG0693@1|root,COG0693@2|Bacteria,1MVTT@1224|Proteobacteria,2TT0C@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	intracellular protease amidase	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
CMS1_k127_2747952_4	1449350.OCH239_18545	6.989e-89	297.0	COG0702@1|root,COG0702@2|Bacteria,1REY2@1224|Proteobacteria,2TS22@28211|Alphaproteobacteria,4KNTP@93682|Roseivivax	28211|Alphaproteobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
CMS1_k127_2747952_9	1502850.FG91_03750	1.653e-31	124.0	2AMM4@1|root,31CH4@2|Bacteria,1NASQ@1224|Proteobacteria,2UI4C@28211|Alphaproteobacteria,2K7B5@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2747952_2	1174684.EBMC1_15684	1.665e-120	389.0	COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,2TRI2@28211|Alphaproteobacteria,2K0EP@204457|Sphingomonadales	204457|Sphingomonadales	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
CMS1_k127_2747952_10	279238.Saro_0007	1.452e-27	117.0	2EQ70@1|root,33HT9@2|Bacteria,1NIHT@1224|Proteobacteria,2UK3J@28211|Alphaproteobacteria,2K5XI@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2747952_12	441620.Mpop_5133	1.606e-06	50.0	COG1961@1|root,COG1961@2|Bacteria,1PWCY@1224|Proteobacteria,2TVME@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
CMS1_k127_2747952_1	1096930.L284_10995	1.775e-126	424.0	COG4585@1|root,COG4585@2|Bacteria,1RKV1@1224|Proteobacteria,2U32D@28211|Alphaproteobacteria,2K2T6@204457|Sphingomonadales	204457|Sphingomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
CMS1_k127_2747952_6	1096930.L284_11000	2.741e-65	229.0	COG2197@1|root,COG2197@2|Bacteria,1RGH6@1224|Proteobacteria,2U81B@28211|Alphaproteobacteria,2K60U@204457|Sphingomonadales	204457|Sphingomonadales	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS1_k127_2747952_5	1096930.L284_11005	1.973e-80	280.0	COG0392@1|root,COG0392@2|Bacteria,1R5W7@1224|Proteobacteria,2URY0@28211|Alphaproteobacteria,2KAGU@204457|Sphingomonadales	204457|Sphingomonadales	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
CMS1_k127_2747952_3	1353531.AZNX01000033_gene4069	1.304e-119	397.0	COG0451@1|root,COG0451@2|Bacteria,1MW3K@1224|Proteobacteria,2TTTJ@28211|Alphaproteobacteria,4BCIX@82115|Rhizobiaceae	28211|Alphaproteobacteria	GM	NAD(P)H-binding	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
CMS1_k127_2747952_0	1096930.L284_11010	1.885e-205	650.0	COG2303@1|root,COG2303@2|Bacteria,1P9UF@1224|Proteobacteria,2U3F9@28211|Alphaproteobacteria,2K2U7@204457|Sphingomonadales	204457|Sphingomonadales	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
CMS1_k127_2747952_7	1096930.L284_11020	1.67e-51	189.0	COG0546@1|root,COG0546@2|Bacteria,1RJNY@1224|Proteobacteria,2USW5@28211|Alphaproteobacteria,2KAMM@204457|Sphingomonadales	204457|Sphingomonadales	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
CMS1_k127_2758166_8	1120705.FG95_01682	1.58e-42	160.0	COG0583@1|root,COG0583@2|Bacteria,1MVA1@1224|Proteobacteria,2TSUS@28211|Alphaproteobacteria,2JZYZ@204457|Sphingomonadales	204457|Sphingomonadales	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	ko:K04761	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
CMS1_k127_2758166_3	1123270.ATUR01000002_gene2259	2.743e-85	291.0	COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,2U59K@28211|Alphaproteobacteria,2K180@204457|Sphingomonadales	204457|Sphingomonadales	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
CMS1_k127_2758166_4	1123270.ATUR01000002_gene2260	4.883e-63	218.0	COG3761@1|root,COG3761@2|Bacteria,1RHS3@1224|Proteobacteria,2U95G@28211|Alphaproteobacteria,2K5FH@204457|Sphingomonadales	204457|Sphingomonadales	C	NADH ubiquinone oxidoreductase 17.2 kD subunit	-	-	-	-	-	-	-	-	-	-	-	-	NDUFA12
CMS1_k127_2758166_6	1545915.JROG01000004_gene1776	6.747e-47	175.0	COG1430@1|root,COG1430@2|Bacteria,1MZBJ@1224|Proteobacteria,2UBSI@28211|Alphaproteobacteria,2K5JY@204457|Sphingomonadales	204457|Sphingomonadales	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
CMS1_k127_2758166_9	1234595.C725_0724	3.403e-42	163.0	COG1278@1|root,COG1278@2|Bacteria,1RAUE@1224|Proteobacteria,2U0S7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Cold shock	cspB	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
CMS1_k127_2758166_7	1346791.M529_08110	2.861e-44	168.0	COG2137@1|root,COG2137@2|Bacteria,1N2EE@1224|Proteobacteria,2U96W@28211|Alphaproteobacteria,2K59F@204457|Sphingomonadales	204457|Sphingomonadales	S	Regulatory protein RecX	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
CMS1_k127_2758166_0	1346791.M529_08115	4.065e-291	902.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TW3C@28211|Alphaproteobacteria,2K0HU@204457|Sphingomonadales	204457|Sphingomonadales	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C_2
CMS1_k127_2758166_1	1088721.NSU_0380	1.305e-278	877.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria,2K07A@204457|Sphingomonadales	204457|Sphingomonadales	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4
CMS1_k127_2758166_2	1248760.ANFZ01000004_gene1936	9.574e-97	323.0	COG1192@1|root,COG1192@2|Bacteria,1R62T@1224|Proteobacteria,2TUDH@28211|Alphaproteobacteria,2JZW4@204457|Sphingomonadales	204457|Sphingomonadales	D	Chromosome partitioning	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
CMS1_k127_2758166_5	702113.PP1Y_AT8922	1.212e-51	184.0	COG1393@1|root,COG1393@2|Bacteria,1MZ4Z@1224|Proteobacteria,2UAPZ@28211|Alphaproteobacteria,2KD28@204457|Sphingomonadales	204457|Sphingomonadales	P	Arsenate reductase	-	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC
CMS1_k127_2761587_3	1123270.ATUR01000004_gene1802	1.48e-12	73.0	291EX@1|root,2ZP1S@2|Bacteria,1RF3T@1224|Proteobacteria,2U83Z@28211|Alphaproteobacteria,2K4S8@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Mitofilin
CMS1_k127_2761587_2	1120705.FG95_03469	5.345e-40	158.0	COG1587@1|root,COG1587@2|Bacteria,1NMTP@1224|Proteobacteria,2UMED@28211|Alphaproteobacteria,2K52Q@204457|Sphingomonadales	204457|Sphingomonadales	H	Uroporphyrinogen-III synthase	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
CMS1_k127_2761587_1	627192.SLG_00500	1.432e-99	334.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,2TS3D@28211|Alphaproteobacteria,2K19Y@204457|Sphingomonadales	204457|Sphingomonadales	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
CMS1_k127_2761587_0	1545915.JROG01000008_gene3307	1.358e-125	405.0	COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,2TSF7@28211|Alphaproteobacteria,2K0S9@204457|Sphingomonadales	204457|Sphingomonadales	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
CMS1_k127_2774123_0	1545915.JROG01000003_gene812	1.715e-266	826.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,2TSNK@28211|Alphaproteobacteria,2K0EQ@204457|Sphingomonadales	204457|Sphingomonadales	C	NADH ubiquinone oxidoreductase subunit	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
CMS1_k127_2774123_2	1545915.JROG01000003_gene813	1.962e-201	637.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,2TQMX@28211|Alphaproteobacteria,2K08E@204457|Sphingomonadales	204457|Sphingomonadales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
CMS1_k127_2774123_6	1096930.L284_15820	2.409e-68	242.0	COG0340@1|root,COG0340@2|Bacteria,1MWCC@1224|Proteobacteria,2TS82@28211|Alphaproteobacteria,2JZZZ@204457|Sphingomonadales	204457|Sphingomonadales	H	biotin lipoate A B protein ligase	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,BPL_LplA_LipB_2
CMS1_k127_2774123_4	1219035.NT2_02_00310	6.48e-117	381.0	COG1521@1|root,COG1521@2|Bacteria,1MUYA@1224|Proteobacteria,2TS5A@28211|Alphaproteobacteria,2K0SW@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
CMS1_k127_2774123_1	1192759.AKIB01000116_gene3680	5.647e-262	817.0	COG0595@1|root,COG0595@2|Bacteria,1MUGV@1224|Proteobacteria,2TQTR@28211|Alphaproteobacteria,2K04C@204457|Sphingomonadales	204457|Sphingomonadales	S	metallo-beta-lactamase	-	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
CMS1_k127_2774123_9	1144307.PMI04_04217	3.284e-23	101.0	COG5454@1|root,COG5454@2|Bacteria,1N8U9@1224|Proteobacteria,2UGCD@28211|Alphaproteobacteria,2K711@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF1467)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1467
CMS1_k127_2774123_3	1545915.JROG01000003_gene748	4.44e-120	414.0	COG1196@1|root,COG1196@2|Bacteria,1MVEP@1224|Proteobacteria,2TR50@28211|Alphaproteobacteria,2K0N2@204457|Sphingomonadales	204457|Sphingomonadales	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2774123_7	1207055.C100_12670	8.199e-37	141.0	2AFMU@1|root,315P6@2|Bacteria,1NDJZ@1224|Proteobacteria,2UHNJ@28211|Alphaproteobacteria,2K65G@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2774123_11	555217.Zmob_1232	4.826e-08	65.0	2AKKZ@1|root,31BDD@2|Bacteria,1NNE3@1224|Proteobacteria,2UMPR@28211|Alphaproteobacteria,2K4ZT@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2774123_10	392499.Swit_3210	4.271e-13	81.0	COG5330@1|root,COG5330@2|Bacteria,1R3VY@1224|Proteobacteria,2TVFN@28211|Alphaproteobacteria,2K2VA@204457|Sphingomonadales	204457|Sphingomonadales	S	Uncharacterised protein conserved in bacteria (DUF2336)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2336
CMS1_k127_2774123_5	1192759.AKIB01000116_gene3674	4.803e-109	368.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2U3HG@28211|Alphaproteobacteria,2K0AE@204457|Sphingomonadales	204457|Sphingomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
CMS1_k127_2774123_8	158500.BV97_00629	7.421e-34	130.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,2TS63@28211|Alphaproteobacteria,2K0JS@204457|Sphingomonadales	204457|Sphingomonadales	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
CMS1_k127_2774207_1	279238.Saro_3161	1.227e-220	695.0	COG0318@1|root,COG0318@2|Bacteria,1MUIC@1224|Proteobacteria,2TRRZ@28211|Alphaproteobacteria,2K2K3@204457|Sphingomonadales	204457|Sphingomonadales	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
CMS1_k127_2774207_2	161528.ED21_18697	1.053e-198	632.0	COG2124@1|root,COG2124@2|Bacteria,1MV8Q@1224|Proteobacteria,2TU15@28211|Alphaproteobacteria,2K1GE@204457|Sphingomonadales	204457|Sphingomonadales	Q	cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
CMS1_k127_2774207_0	1479239.JQMU01000001_gene1727	1.383e-263	816.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,2JZVD@204457|Sphingomonadales	204457|Sphingomonadales	C	belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS1_k127_2774207_3	1537715.JQFJ01000002_gene2405	3.358e-113	370.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2TSA0@28211|Alphaproteobacteria,2K081@204457|Sphingomonadales	204457|Sphingomonadales	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
CMS1_k127_2779952_8	627192.SLG_06570	1.108e-62	217.0	COG0662@1|root,COG0662@2|Bacteria,1RJ7D@1224|Proteobacteria,2UAG4@28211|Alphaproteobacteria,2K4M6@204457|Sphingomonadales	204457|Sphingomonadales	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS1_k127_2779952_7	450851.PHZ_c0045	1.445e-71	248.0	2A23N@1|root,30QDW@2|Bacteria,1RGGT@1224|Proteobacteria,2U84G@28211|Alphaproteobacteria,2KK6N@204458|Caulobacterales	204458|Caulobacterales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2779952_9	1088721.NSU_3336	1.188e-62	219.0	COG3118@1|root,COG3118@2|Bacteria,1RHUA@1224|Proteobacteria,2U97P@28211|Alphaproteobacteria,2K5VB@204457|Sphingomonadales	204457|Sphingomonadales	O	Thioredoxin	-	-	1.8.1.8	ko:K03672	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Thioredoxin
CMS1_k127_2779952_6	1336235.JAEG01000012_gene4138	4.27e-87	298.0	COG1105@1|root,COG1105@2|Bacteria,1MVNW@1224|Proteobacteria,2U1H0@28211|Alphaproteobacteria,4BAMS@82115|Rhizobiaceae	28211|Alphaproteobacteria	H	Belongs to the carbohydrate kinase PfkB family	-	-	2.7.1.11	ko:K16370	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
CMS1_k127_2779952_11	359.CN09_32775	1.697e-56	207.0	COG0664@1|root,COG0664@2|Bacteria,1NEQM@1224|Proteobacteria,2U7UR@28211|Alphaproteobacteria,4BEEB@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
CMS1_k127_2779952_10	1123269.NX02_09275	1.611e-57	209.0	COG4566@1|root,COG4566@2|Bacteria,1N6WR@1224|Proteobacteria,2TUND@28211|Alphaproteobacteria,2K16W@204457|Sphingomonadales	204457|Sphingomonadales	K	part of global network that controls expression of aerobic respiratory terminal oxidases and carbon and nitrogen metabolic enzymes	-	-	-	ko:K14987	ko02020,map02020	M00524	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
CMS1_k127_2779952_0	1088721.NSU_0076	0.0	3214.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,2TSAJ@28211|Alphaproteobacteria,2K0DW@204457|Sphingomonadales	204457|Sphingomonadales	G	Glycosyl hydrolase 36 superfamily, catalytic domain	-	-	-	ko:K13688	-	-	-	-	ko00000,ko01000,ko01003	-	GH94,GT84	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
CMS1_k127_2779952_12	1088721.NSU_0079	6.775e-48	186.0	COG0589@1|root,COG0589@2|Bacteria,1NAHQ@1224|Proteobacteria,2VFNF@28211|Alphaproteobacteria,2KDXT@204457|Sphingomonadales	204457|Sphingomonadales	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS1_k127_2779952_14	1500306.JQLA01000054_gene3287	1.626e-28	124.0	COG0664@1|root,COG0664@2|Bacteria,1MVGE@1224|Proteobacteria,2U9WP@28211|Alphaproteobacteria,4BA2U@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	family. transcriptional regulator	fixKf	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CMS1_k127_2779952_1	243231.GSU0803	2.992e-293	923.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,42MW3@68525|delta/epsilon subdivisions,2WJRZ@28221|Deltaproteobacteria,43SWM@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
CMS1_k127_2779952_4	1123269.NX02_09395	5.083e-148	477.0	COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,2TTI9@28211|Alphaproteobacteria,2K29S@204457|Sphingomonadales	204457|Sphingomonadales	S	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N
CMS1_k127_2779952_5	153948.NAL212_2583	7.639e-97	330.0	COG0530@1|root,COG0530@2|Bacteria,1PW8G@1224|Proteobacteria,2VMK4@28216|Betaproteobacteria,373TU@32003|Nitrosomonadales	28216|Betaproteobacteria	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
CMS1_k127_2779952_2	1112212.JH584235_gene3611	8.052e-272	860.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2TRZD@28211|Alphaproteobacteria,2K18Q@204457|Sphingomonadales	204457|Sphingomonadales	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
CMS1_k127_2779952_13	472759.Nhal_3186	3.31e-30	125.0	COG5502@1|root,COG5502@2|Bacteria,1NB8V@1224|Proteobacteria,1SETZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Uncharacterized conserved protein (DUF2267)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2267
CMS1_k127_2779952_3	46429.BV95_02812	1.631e-218	684.0	COG2312@1|root,COG2312@2|Bacteria,1MU2S@1224|Proteobacteria,2TWB5@28211|Alphaproteobacteria,2K7QR@204457|Sphingomonadales	204457|Sphingomonadales	S	Erythromycin esterase	-	-	-	-	-	-	-	-	-	-	-	-	Erythro_esteras
CMS1_k127_2785908_4	392499.Swit_1839	7.326e-13	72.0	COG1053@1|root,COG1053@2|Bacteria,1MURY@1224|Proteobacteria,2UQ4B@28211|Alphaproteobacteria,2KD4E@204457|Sphingomonadales	204457|Sphingomonadales	C	HI0933-like protein	-	-	1.3.99.4	ko:K05898	ko00984,ko01100,ko01120,map00984,map01100,map01120	-	R09884	RC00991	ko00000,ko00001,ko01000	-	-	-	FAD_binding_2
CMS1_k127_2785908_2	392499.Swit_1838	6.993e-145	471.0	COG0427@1|root,COG0427@2|Bacteria,1MUGE@1224|Proteobacteria,2U67S@28211|Alphaproteobacteria,2KDDK@204457|Sphingomonadales	204457|Sphingomonadales	C	Acetyl-CoA hydrolase/transferase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C
CMS1_k127_2785908_3	749414.SBI_00179	2.805e-23	110.0	COG1028@1|root,COG1028@2|Bacteria,2HRAZ@201174|Actinobacteria	201174|Actinobacteria	IQ	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS1_k127_2785908_1	392499.Swit_1836	1.407e-207	650.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TR15@28211|Alphaproteobacteria,2K1CR@204457|Sphingomonadales	204457|Sphingomonadales	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS1_k127_2785908_0	392499.Swit_1830	1.105e-254	796.0	COG1053@1|root,COG1053@2|Bacteria,1MURY@1224|Proteobacteria,2TSRQ@28211|Alphaproteobacteria,2K1EU@204457|Sphingomonadales	204457|Sphingomonadales	C	fumarate reductase	-	-	1.3.99.4	ko:K05898	ko00984,ko01100,ko01120,map00984,map01100,map01120	-	R09884	RC00991	ko00000,ko00001,ko01000	-	-	-	FAD_binding_2
CMS1_k127_2801608_1	1123269.NX02_13255	6.065e-234	731.0	COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,2TRNG@28211|Alphaproteobacteria,2K1MA@204457|Sphingomonadales	204457|Sphingomonadales	O	cytochrome C	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
CMS1_k127_2801608_4	1248760.ANFZ01000004_gene1959	1.556e-53	194.0	COG2332@1|root,COG2332@2|Bacteria,1RHN5@1224|Proteobacteria,2U99J@28211|Alphaproteobacteria,2K56Y@204457|Sphingomonadales	204457|Sphingomonadales	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	ccmE	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
CMS1_k127_2801608_2	1123270.ATUR01000003_gene1068	5.858e-109	357.0	COG0755@1|root,COG0755@2|Bacteria,1MU61@1224|Proteobacteria,2TSW8@28211|Alphaproteobacteria,2K13J@204457|Sphingomonadales	204457|Sphingomonadales	O	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmC	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
CMS1_k127_2801608_0	46429.BV95_00229	4.04e-247	773.0	COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,2TUH6@28211|Alphaproteobacteria,2K0ZF@204457|Sphingomonadales	204457|Sphingomonadales	P	Sulfate transporter	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
CMS1_k127_2801608_6	392499.Swit_5392	2.337e-40	151.0	COG1396@1|root,COG1396@2|Bacteria,1MZQK@1224|Proteobacteria,2UCAK@28211|Alphaproteobacteria,2K7KZ@204457|Sphingomonadales	204457|Sphingomonadales	K	XRE family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
CMS1_k127_2801608_5	46429.BV95_00232	2.002e-42	160.0	COG5349@1|root,COG5349@2|Bacteria,1MZDD@1224|Proteobacteria,2UCM4@28211|Alphaproteobacteria,2K5QN@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF983)	-	-	-	-	-	-	-	-	-	-	-	-	DUF983
CMS1_k127_2801608_3	1123270.ATUR01000003_gene1069	6.127e-59	207.0	COG0334@1|root,COG0334@2|Bacteria,1MUXS@1224|Proteobacteria,2VGKD@28211|Alphaproteobacteria,2K0AY@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.9	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	-	R01088,R01434,R02196	RC00006,RC00036	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
CMS1_k127_2808246_5	392499.Swit_0491	7.762e-105	346.0	COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,2TR2M@28211|Alphaproteobacteria,2K2AP@204457|Sphingomonadales	204457|Sphingomonadales	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
CMS1_k127_2808246_3	1123270.ATUR01000010_gene1927	1.153e-191	602.0	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,2TTQ2@28211|Alphaproteobacteria,2K10A@204457|Sphingomonadales	204457|Sphingomonadales	D	rod shape-determining protein MreB	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
CMS1_k127_2808246_6	1545915.JROG01000003_gene617	1.594e-87	298.0	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,2U1FY@28211|Alphaproteobacteria,2K18A@204457|Sphingomonadales	204457|Sphingomonadales	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
CMS1_k127_2808246_7	1123269.NX02_05500	2.709e-50	184.0	2923J@1|root,2ZPNK@2|Bacteria,1NHX1@1224|Proteobacteria,2UC0M@28211|Alphaproteobacteria,2K5BN@204457|Sphingomonadales	204457|Sphingomonadales	S	rod shape-determining protein MreD	-	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
CMS1_k127_2808246_0	1123270.ATUR01000010_gene1924	8.959e-312	967.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,2TRXN@28211|Alphaproteobacteria,2JZYI@204457|Sphingomonadales	204457|Sphingomonadales	M	Penicillin-binding Protein	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
CMS1_k127_2808246_4	1123270.ATUR01000010_gene1923	1.047e-169	539.0	COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,2TSM0@28211|Alphaproteobacteria,2K0FR@204457|Sphingomonadales	204457|Sphingomonadales	M	Peptidoglycan polymerase that is essential for cell wall elongation	mrdB	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
CMS1_k127_2808246_2	1123270.ATUR01000004_gene1603	2.152e-220	691.0	COG1249@1|root,COG1249@2|Bacteria,1MXQ3@1224|Proteobacteria,2U25H@28211|Alphaproteobacteria,2K35W@204457|Sphingomonadales	204457|Sphingomonadales	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
CMS1_k127_2808246_1	1123270.ATUR01000004_gene1602	8.575e-252	781.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,2K0Q5@204457|Sphingomonadales	204457|Sphingomonadales	C	COG1012 NAD-dependent aldehyde dehydrogenases	-	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS1_k127_281460_0	1207055.C100_14130	2.008e-200	633.0	COG5316@1|root,COG5316@2|Bacteria,1QCVP@1224|Proteobacteria,2U2ZN@28211|Alphaproteobacteria,2K1T4@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139
CMS1_k127_281460_3	1545915.JROG01000004_gene1934	1.634e-66	234.0	COG1309@1|root,COG1309@2|Bacteria,1R44G@1224|Proteobacteria,2TTF0@28211|Alphaproteobacteria,2K576@204457|Sphingomonadales	204457|Sphingomonadales	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS1_k127_281460_2	1280952.HJA_11070	2.919e-94	312.0	COG0346@1|root,COG0346@2|Bacteria,1R6IN@1224|Proteobacteria,2U85D@28211|Alphaproteobacteria,43Z3Y@69657|Hyphomonadaceae	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS1_k127_281460_1	1207058.L53_11575	2.005e-98	325.0	COG2128@1|root,COG2128@2|Bacteria,1PMH5@1224|Proteobacteria,2TVAY@28211|Alphaproteobacteria,43ZD2@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS1_k127_2821006_1	13689.BV96_01101	3.246e-175	554.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,2TRHQ@28211|Alphaproteobacteria,2K19P@204457|Sphingomonadales	204457|Sphingomonadales	E	Glutamate synthase	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
CMS1_k127_2821006_8	1163407.UU7_06768	1.021e-30	130.0	COG3324@1|root,COG3324@2|Bacteria,1N0AD@1224|Proteobacteria,1S8YM@1236|Gammaproteobacteria,1X7R7@135614|Xanthomonadales	135614|Xanthomonadales	S	Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
CMS1_k127_2821006_3	1123270.ATUR01000005_gene668	1.789e-116	377.0	COG0625@1|root,COG0625@2|Bacteria,1MXM4@1224|Proteobacteria,2TTXD@28211|Alphaproteobacteria,2K1DG@204457|Sphingomonadales	204457|Sphingomonadales	O	Glutathione S-transferase	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N_3
CMS1_k127_2821006_5	1192759.AKIB01000009_gene2553	5.164e-98	325.0	COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,2TRIK@28211|Alphaproteobacteria,2K0DH@204457|Sphingomonadales	204457|Sphingomonadales	H	O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway	ubiG	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23
CMS1_k127_2821006_0	1248760.ANFZ01000018_gene547	1.326e-220	691.0	COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,2TRFA@28211|Alphaproteobacteria,2K044@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
CMS1_k127_2821006_2	1123270.ATUR01000008_gene235	1.956e-168	543.0	COG2070@1|root,COG2070@2|Bacteria,1MWPC@1224|Proteobacteria,2TQRT@28211|Alphaproteobacteria,2K0DQ@204457|Sphingomonadales	204457|Sphingomonadales	S	2-nitropropane dioxygenase	-	-	1.3.1.9	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	NMO,ThiG
CMS1_k127_2821006_9	261292.Nit79A3_2723	4.18e-20	101.0	COG3360@1|root,COG3360@2|Bacteria,1N6UT@1224|Proteobacteria,2VVVU@28216|Betaproteobacteria,373QK@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
CMS1_k127_2821006_6	1123270.ATUR01000008_gene236	4.018e-41	160.0	COG3402@1|root,COG3402@2|Bacteria,1N8GD@1224|Proteobacteria,2UEFP@28211|Alphaproteobacteria,2K6MN@204457|Sphingomonadales	204457|Sphingomonadales	S	Bacterial PH domain	-	-	-	ko:K09167	-	-	-	-	ko00000	-	-	-	bPH_2
CMS1_k127_2821006_4	1248760.ANFZ01000024_gene1701	2.438e-110	377.0	COG3428@1|root,COG3428@2|Bacteria,1RAI7@1224|Proteobacteria,2VGGC@28211|Alphaproteobacteria,2KE3Q@204457|Sphingomonadales	204457|Sphingomonadales	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
CMS1_k127_2821006_7	1123270.ATUR01000008_gene238	7.149e-39	151.0	COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,2TSQN@28211|Alphaproteobacteria,2KCC8@204457|Sphingomonadales	204457|Sphingomonadales	C	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
CMS1_k127_2830710_5	158500.BV97_02146	6.262e-139	455.0	COG5010@1|root,COG5010@2|Bacteria,1R7S3@1224|Proteobacteria,2TUMP@28211|Alphaproteobacteria,2K076@204457|Sphingomonadales	204457|Sphingomonadales	U	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF1570
CMS1_k127_2830710_16	13689.BV96_00296	1.966e-46	175.0	COG3247@1|root,COG3247@2|Bacteria,1RH69@1224|Proteobacteria,2U93B@28211|Alphaproteobacteria,2K4EQ@204457|Sphingomonadales	204457|Sphingomonadales	S	Short repeat of unknown function (DUF308)	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
CMS1_k127_2830710_14	1044.EH31_00030	1.106e-47	175.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,2UB52@28211|Alphaproteobacteria,2KDCN@204457|Sphingomonadales	204457|Sphingomonadales	O	small heat shock protein	-	-	-	-	-	-	-	-	-	-	-	-	HSP20
CMS1_k127_2830710_0	1545915.JROG01000003_gene651	7.705e-270	842.0	COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,2TSUQ@28211|Alphaproteobacteria,2K0GU@204457|Sphingomonadales	204457|Sphingomonadales	O	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
CMS1_k127_2830710_9	1123270.ATUR01000002_gene2086	7.731e-78	268.0	COG3751@1|root,COG3751@2|Bacteria,1NG7K@1224|Proteobacteria,2U773@28211|Alphaproteobacteria,2K1IN@204457|Sphingomonadales	204457|Sphingomonadales	O	Prolyl 4-hydroxylase alpha subunit homologues.	-	-	1.14.11.2	ko:K00472	ko00330,ko01100,map00330,map01100	-	R01252	RC00478	ko00000,ko00001,ko01000	-	-	-	2OG-FeII_Oxy_3
CMS1_k127_2830710_2	1123270.ATUR01000002_gene2145	3.023e-190	605.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,2TTYC@28211|Alphaproteobacteria,2K0Q2@204457|Sphingomonadales	204457|Sphingomonadales	Q	COG1228 Imidazolonepropionase and related amidohydrolases	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
CMS1_k127_2830710_7	1248760.ANFZ01000004_gene1968	1.496e-90	304.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,2TVD3@28211|Alphaproteobacteria,2K26W@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
CMS1_k127_2830710_11	317655.Sala_1036	2.698e-61	223.0	COG5455@1|root,COG5455@2|Bacteria,1MYUG@1224|Proteobacteria,2UBNQ@28211|Alphaproteobacteria,2KE3F@204457|Sphingomonadales	204457|Sphingomonadales	S	Nickel/cobalt transporter regulator	-	-	-	-	-	-	-	-	-	-	-	-	RcnB
CMS1_k127_2830710_1	291985.CCSI01000001_gene1883	1.611e-236	737.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,2U25Z@28211|Alphaproteobacteria,2K11Z@204457|Sphingomonadales	204457|Sphingomonadales	I	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
CMS1_k127_2830710_13	1044.EH31_06820	4.104e-57	202.0	COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,2U93Y@28211|Alphaproteobacteria,2K5JX@204457|Sphingomonadales	204457|Sphingomonadales	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
CMS1_k127_2830710_10	1112212.JH584235_gene470	4.408e-64	222.0	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,2U9BV@28211|Alphaproteobacteria,2K3VV@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
CMS1_k127_2830710_3	1044.EH31_12310	3.727e-166	533.0	COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,2TSXS@28211|Alphaproteobacteria,2K0MM@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG,ThiS
CMS1_k127_2830710_17	1123270.ATUR01000008_gene397	2.18e-32	132.0	2AMHV@1|root,31CDG@2|Bacteria,1RGVA@1224|Proteobacteria,2U98Q@28211|Alphaproteobacteria,2K54G@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF1153)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1153
CMS1_k127_2830710_15	1379701.JPJC01000276_gene604	9.71e-47	184.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TZWG@28211|Alphaproteobacteria,2KAS0@204457|Sphingomonadales	204457|Sphingomonadales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL
CMS1_k127_2830710_4	161528.ED21_24511	1.823e-147	482.0	COG1020@1|root,COG1020@2|Bacteria,1N7HY@1224|Proteobacteria,2TRZV@28211|Alphaproteobacteria,2K46G@204457|Sphingomonadales	204457|Sphingomonadales	Q	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
CMS1_k127_2830710_6	1123059.KB823011_gene1422	1.275e-112	371.0	COG1028@1|root,COG1028@2|Bacteria,1MXNQ@1224|Proteobacteria,2TS6G@28211|Alphaproteobacteria,43W8V@69657|Hyphomonadaceae	28211|Alphaproteobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	MA20_27450	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS1_k127_2830710_12	394221.Mmar10_1649	5.368e-58	206.0	COG2030@1|root,COG2030@2|Bacteria,1RHPH@1224|Proteobacteria,2U9GG@28211|Alphaproteobacteria,43Y20@69657|Hyphomonadaceae	28211|Alphaproteobacteria	I	MaoC like domain	nodN	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
CMS1_k127_2830710_8	582515.KR51_00028010	2.392e-83	280.0	COG1064@1|root,COG1064@2|Bacteria,1G0B9@1117|Cyanobacteria	1117|Cyanobacteria	C	alcohol dehydrogenase	-	-	-	ko:K12957	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_2840321_2	1379701.JPJC01000057_gene3232	1.316e-115	378.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2TQND@28211|Alphaproteobacteria,2K04K@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CMS1_k127_2840321_0	1123270.ATUR01000004_gene1498	3.167e-261	818.0	COG0025@1|root,COG0025@2|Bacteria,1QTUE@1224|Proteobacteria,2TW3I@28211|Alphaproteobacteria,2K36K@204457|Sphingomonadales	204457|Sphingomonadales	P	antiporter	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,TrkA_N
CMS1_k127_2840321_3	383381.EH30_13760	3.983e-87	293.0	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,2TR5Z@28211|Alphaproteobacteria,2K0C6@204457|Sphingomonadales	204457|Sphingomonadales	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
CMS1_k127_2840321_6	158500.BV97_02776	2.484e-46	174.0	COG0352@1|root,COG0352@2|Bacteria,1RKGX@1224|Proteobacteria,2UB4W@28211|Alphaproteobacteria,2K57F@204457|Sphingomonadales	204457|Sphingomonadales	H	Thiamine monophosphate synthase	-	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
CMS1_k127_2840321_5	1248760.ANFZ01000006_gene2335	1.424e-46	178.0	2C7BT@1|root,33MZ9@2|Bacteria,1NMQ4@1224|Proteobacteria,2UG5B@28211|Alphaproteobacteria,2K40I@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Porin_4
CMS1_k127_2840321_4	1120705.FG95_02387	5.969e-61	216.0	2C2J5@1|root,315UG@2|Bacteria,1RHAH@1224|Proteobacteria,2U94W@28211|Alphaproteobacteria,2K4E5@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF3576)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3576
CMS1_k127_2840321_1	392499.Swit_2852	1.076e-212	666.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,2TQPK@28211|Alphaproteobacteria,2K0Q0@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
CMS1_k127_2846221_2	1219035.NT2_01_00850	7.406e-98	323.0	COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,2TUWE@28211|Alphaproteobacteria,2K0HQ@204457|Sphingomonadales	204457|Sphingomonadales	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
CMS1_k127_2846221_0	1545915.JROG01000003_gene795	6.691e-138	443.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,2TR06@28211|Alphaproteobacteria,2K0TX@204457|Sphingomonadales	204457|Sphingomonadales	G	Inositol monophosphatase	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
CMS1_k127_2846221_3	5147.XP_003343056.1	7.659e-38	145.0	COG0838@1|root,KOG4662@2759|Eukaryota	2759|Eukaryota	C	NADH dehydrogenase (quinone) activity	ND3	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0007005,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009314,GO:0009416,GO:0009628,GO:0009642,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0010257,GO:0014070,GO:0015980,GO:0016020,GO:0016043,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0019866,GO:0022607,GO:0022900,GO:0022904,GO:0030964,GO:0031090,GO:0031960,GO:0031966,GO:0031967,GO:0031975,GO:0032870,GO:0032981,GO:0032991,GO:0033108,GO:0033993,GO:0034622,GO:0034641,GO:0042221,GO:0042773,GO:0042775,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045271,GO:0045333,GO:0046034,GO:0046483,GO:0048545,GO:0050136,GO:0050896,GO:0051384,GO:0051716,GO:0055086,GO:0055114,GO:0065003,GO:0070469,GO:0070887,GO:0071310,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071495,GO:0071704,GO:0071840,GO:0072521,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204	1.6.5.3	ko:K03880	ko00190,ko01100,ko04714,ko04723,ko05012,map00190,map01100,map04714,map04723,map05012	M00142	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko03029	3.D.1.6	-	-	Oxidored_q4
CMS1_k127_2846221_1	702113.PP1Y_AT27416	3.241e-108	355.0	COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,2TQK3@28211|Alphaproteobacteria,2K0KE@204457|Sphingomonadales	204457|Sphingomonadales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
CMS1_k127_284914_1	1385517.N800_02820	1.11e-71	256.0	COG1680@1|root,COG1680@2|Bacteria,1RIYG@1224|Proteobacteria,1SB75@1236|Gammaproteobacteria,1XBF5@135614|Xanthomonadales	135614|Xanthomonadales	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS1_k127_284914_2	1537715.JQFJ01000002_gene1148	1.318e-50	187.0	COG0702@1|root,COG0702@2|Bacteria,1MZG7@1224|Proteobacteria,2UBX1@28211|Alphaproteobacteria,2K6FP@204457|Sphingomonadales	204457|Sphingomonadales	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
CMS1_k127_284914_0	1123270.ATUR01000002_gene2476	5.598e-165	524.0	COG0232@1|root,COG0232@2|Bacteria,1MVQ2@1224|Proteobacteria,2TRCD@28211|Alphaproteobacteria,2K0JG@204457|Sphingomonadales	204457|Sphingomonadales	F	dGTPase family. Type 2 subfamily	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
CMS1_k127_2859971_2	237727.NAP1_05705	2.217e-46	173.0	COG5319@1|root,COG5319@2|Bacteria,1MZN2@1224|Proteobacteria,2UBTA@28211|Alphaproteobacteria,2K54Q@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1178
CMS1_k127_2859971_0	392499.Swit_0557	3.992e-103	342.0	COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,2TRGZ@28211|Alphaproteobacteria,2K16U@204457|Sphingomonadales	204457|Sphingomonadales	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	ko:K11206	-	-	-	-	ko00000,ko01000	-	-	-	CN_hydrolase
CMS1_k127_2859971_3	1248760.ANFZ01000009_gene1330	6.393e-32	126.0	COG0695@1|root,COG0695@2|Bacteria,1N72P@1224|Proteobacteria,2UFM1@28211|Alphaproteobacteria,2K5VT@204457|Sphingomonadales	204457|Sphingomonadales	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	grxC	-	-	ko:K03676	-	-	-	-	ko00000,ko03110	-	-	-	Glutaredoxin
CMS1_k127_2859971_1	1248760.ANFZ01000009_gene1331	8.012e-78	269.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,2TV7G@28211|Alphaproteobacteria,2K09E@204457|Sphingomonadales	204457|Sphingomonadales	S	Competence protein	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
CMS1_k127_2859971_4	1030157.AFMP01000031_gene2984	3.24e-08	57.0	COG0500@1|root,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,2TRFS@28211|Alphaproteobacteria,2K0V6@204457|Sphingomonadales	204457|Sphingomonadales	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
CMS1_k127_2874538_4	1545915.JROG01000001_gene366	1.835e-77	262.0	COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,2TSFS@28211|Alphaproteobacteria,2K1E7@204457|Sphingomonadales	204457|Sphingomonadales	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,Na_sulph_symp,TrkA_C
CMS1_k127_2874538_5	118166.JH976537_gene3179	4.249e-11	72.0	2A97U@1|root,30YCI@2|Bacteria,1G5XN@1117|Cyanobacteria,1HCE9@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Germane
CMS1_k127_2874538_0	1219045.BV98_000820	1.24e-200	628.0	COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,2TQY2@28211|Alphaproteobacteria,2K0X4@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
CMS1_k127_2874538_1	1545915.JROG01000001_gene369	1.141e-151	481.0	COG0623@1|root,COG0623@2|Bacteria,1MV05@1224|Proteobacteria,2TSU4@28211|Alphaproteobacteria,2K0BH@204457|Sphingomonadales	204457|Sphingomonadales	I	Enoyl- acyl-carrier-protein reductase NADH	fabI	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS1_k127_2874538_3	1123270.ATUR01000008_gene405	5.107e-99	333.0	COG1295@1|root,COG1295@2|Bacteria,1MXQA@1224|Proteobacteria,2TTN5@28211|Alphaproteobacteria,2K0UY@204457|Sphingomonadales	204457|Sphingomonadales	S	ribonuclease BN	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
CMS1_k127_2874538_2	1174684.EBMC1_13551	4.953e-129	418.0	COG0484@1|root,COG2214@1|root,COG0484@2|Bacteria,COG2214@2|Bacteria,1MUZ4@1224|Proteobacteria,2TR01@28211|Alphaproteobacteria,2K1JP@204457|Sphingomonadales	204457|Sphingomonadales	O	molecular chaperone	dnaJ_2	-	-	-	-	-	-	-	-	-	-	-	DnaJ,DnaJ_C
CMS1_k127_2882748_1	1545915.JROG01000001_gene427	5.296e-161	514.0	COG0624@1|root,COG0624@2|Bacteria,1MUSU@1224|Proteobacteria,2TRTW@28211|Alphaproteobacteria,2K0AC@204457|Sphingomonadales	204457|Sphingomonadales	E	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases	-	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
CMS1_k127_2882748_0	1248760.ANFZ01000006_gene2741	0.0	1119.0	COG2225@1|root,COG2225@2|Bacteria,1MVEV@1224|Proteobacteria,2TS9R@28211|Alphaproteobacteria,2K0KC@204457|Sphingomonadales	204457|Sphingomonadales	C	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA	glcB	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
CMS1_k127_2882748_2	1122970.AUHC01000008_gene45	5.305e-121	396.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,2TRD9@28211|Alphaproteobacteria,2K042@204457|Sphingomonadales	204457|Sphingomonadales	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
CMS1_k127_2882748_3	1248760.ANFZ01000009_gene1309	1.089e-63	222.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,2TSKF@28211|Alphaproteobacteria,2K0HZ@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)	pdxA	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
CMS1_k127_2905664_1	392499.Swit_1842	5.426e-197	619.0	COG1960@1|root,COG1960@2|Bacteria,1QU1U@1224|Proteobacteria,2TRIU@28211|Alphaproteobacteria,2K3BT@204457|Sphingomonadales	204457|Sphingomonadales	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS1_k127_2905664_4	1030157.AFMP01000039_gene1322	3.628e-36	139.0	COG5470@1|root,COG5470@2|Bacteria,1Q8BE@1224|Proteobacteria,2VEHQ@28211|Alphaproteobacteria,2K7WM@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF1330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1330
CMS1_k127_2905664_3	1030157.AFMP01000039_gene1319	3.321e-116	381.0	COG1028@1|root,COG1028@2|Bacteria,1MXVZ@1224|Proteobacteria,2U2P1@28211|Alphaproteobacteria,2K8RF@204457|Sphingomonadales	204457|Sphingomonadales	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS1_k127_2905664_0	1030157.AFMP01000039_gene1318	1.415e-213	670.0	COG0183@1|root,COG0183@2|Bacteria,1MU8C@1224|Proteobacteria,2TS6P@28211|Alphaproteobacteria,2K3AY@204457|Sphingomonadales	204457|Sphingomonadales	I	Thiolase, C-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
CMS1_k127_2905664_2	392499.Swit_1856	5.52e-174	561.0	COG1545@1|root,COG3425@1|root,COG1545@2|Bacteria,COG3425@2|Bacteria,1QV6D@1224|Proteobacteria,2TTB1@28211|Alphaproteobacteria,2K2KH@204457|Sphingomonadales	204457|Sphingomonadales	I	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	-	-	-	-	-	-	-	-	-	ACP_syn_III_C,OB_aCoA_assoc
CMS1_k127_2940525_4	1114970.PSF113_5149	1.685e-28	120.0	COG2951@1|root,COG3409@1|root,COG2951@2|Bacteria,COG3409@2|Bacteria,1MUZ3@1224|Proteobacteria,1RMQ6@1236|Gammaproteobacteria,1YMXY@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	M	Murein transglycosylase	-	-	-	ko:K08305	-	-	-	-	ko00000,ko01000,ko01011	-	GH103	-	PG_binding_1,SLT_2
CMS1_k127_2940525_1	1502850.FG91_00324	1.306e-89	307.0	COG0797@1|root,COG3147@1|root,COG0797@2|Bacteria,COG3147@2|Bacteria,1MZ8S@1224|Proteobacteria,2TUER@28211|Alphaproteobacteria,2K4AD@204457|Sphingomonadales	204457|Sphingomonadales	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,SPOR
CMS1_k127_2940525_0	1248760.ANFZ01000009_gene1154	4.008e-161	515.0	COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,2TS1P@28211|Alphaproteobacteria,2K17Y@204457|Sphingomonadales	204457|Sphingomonadales	M	Belongs to the peptidase S11 family	dac	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
CMS1_k127_2940525_2	1331060.RLDS_06215	2.164e-71	247.0	COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,2U72D@28211|Alphaproteobacteria,2K3VU@204457|Sphingomonadales	204457|Sphingomonadales	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
CMS1_k127_2940525_3	745310.G432_00625	9.144e-29	122.0	COG0470@1|root,COG0470@2|Bacteria,1MY1W@1224|Proteobacteria,2TV3E@28211|Alphaproteobacteria,2JZZA@204457|Sphingomonadales	204457|Sphingomonadales	L	DNA polymerase	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2
CMS1_k127_2943429_3	1280949.HAD_10555	2.695e-21	93.0	COG3917@1|root,COG3917@2|Bacteria,1RDNQ@1224|Proteobacteria,2VGB4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	2-hydroxychromene-2-carboxylate isomerase	MA20_32385	-	-	-	-	-	-	-	-	-	-	-	DSBA
CMS1_k127_2943429_1	1545915.JROG01000001_gene463	1.032e-112	367.0	COG0625@1|root,COG0625@2|Bacteria,1MUN3@1224|Proteobacteria,2TTVR@28211|Alphaproteobacteria,2KCX1@204457|Sphingomonadales	204457|Sphingomonadales	O	Belongs to the GST superfamily	-	-	-	ko:K11209	-	-	-	-	ko00000,ko01000	-	-	-	GST_C,GST_C_3,GST_N,GST_N_3
CMS1_k127_2943429_2	1123267.JONN01000002_gene158	9.639e-94	317.0	COG0189@1|root,COG0189@2|Bacteria,1R14H@1224|Proteobacteria,2UB7M@28211|Alphaproteobacteria,2K4CT@204457|Sphingomonadales	204457|Sphingomonadales	HJ	TupA-like ATPgrasp	-	-	-	-	-	-	-	-	-	-	-	-	ATPgrasp_TupA
CMS1_k127_2943429_0	685778.AORL01000019_gene1791	3.696e-177	557.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,2TRE3@28211|Alphaproteobacteria,2K0GY@204457|Sphingomonadales	204457|Sphingomonadales	E	Aminotransferase	-	-	-	ko:K14261	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS1_k127_296011_0	1122970.AUHC01000015_gene2572	0.0	1020.0	COG1629@1|root,COG4773@1|root,COG1629@2|Bacteria,COG4773@2|Bacteria,1QTXJ@1224|Proteobacteria,2U2VU@28211|Alphaproteobacteria,2K27X@204457|Sphingomonadales	204457|Sphingomonadales	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
CMS1_k127_296011_1	1123270.ATUR01000004_gene1700	1.167e-119	387.0	COG0588@1|root,COG0588@2|Bacteria,1MUVE@1224|Proteobacteria,2TSQ0@28211|Alphaproteobacteria,2K06W@204457|Sphingomonadales	204457|Sphingomonadales	G	Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily	gpmA	-	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
CMS1_k127_296011_4	1123267.JONN01000001_gene2301	1.519e-38	151.0	COG2199@1|root,COG2199@2|Bacteria,1Q7FU@1224|Proteobacteria,2TRE7@28211|Alphaproteobacteria,2K6NS@204457|Sphingomonadales	204457|Sphingomonadales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
CMS1_k127_296011_2	1090320.KB900605_gene1217	1.925e-69	239.0	COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,2U58D@28211|Alphaproteobacteria,2K3Z8@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
CMS1_k127_296011_3	317655.Sala_2361	5.613e-64	225.0	COG0026@1|root,COG0026@2|Bacteria,1MU70@1224|Proteobacteria,2TRSV@28211|Alphaproteobacteria,2K0ZI@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
CMS1_k127_2967067_5	1248760.ANFZ01000002_gene3180	7.146e-83	293.0	COG0183@1|root,COG0183@2|Bacteria,1MVPC@1224|Proteobacteria,2VEVD@28211|Alphaproteobacteria,2K31W@204457|Sphingomonadales	204457|Sphingomonadales	I	acetyl-coa acetyltransferase	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	-
CMS1_k127_2967067_2	1123270.ATUR01000003_gene993	9.331e-183	578.0	COG1804@1|root,COG1804@2|Bacteria,1MVY1@1224|Proteobacteria,2TVJ9@28211|Alphaproteobacteria,2K3N7@204457|Sphingomonadales	204457|Sphingomonadales	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
CMS1_k127_2967067_1	1121949.AQXT01000002_gene931	3.822e-183	578.0	COG1960@1|root,COG1960@2|Bacteria,1N05C@1224|Proteobacteria,2TT9T@28211|Alphaproteobacteria,43ZE9@69657|Hyphomonadaceae	28211|Alphaproteobacteria	I	COG1960 Acyl-CoA dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
CMS1_k127_2967067_0	1280944.HY17_14575	1.08e-230	717.0	COG1960@1|root,COG1960@2|Bacteria,1MVJC@1224|Proteobacteria,2TTRD@28211|Alphaproteobacteria,43Z46@69657|Hyphomonadaceae	28211|Alphaproteobacteria	I	COG1960 Acyl-CoA dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS1_k127_2967067_8	1121937.AUHJ01000002_gene3569	2.412e-46	168.0	COG5470@1|root,COG5470@2|Bacteria,1NC8B@1224|Proteobacteria,1SCBU@1236|Gammaproteobacteria,46BHN@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Domain of unknown function (DUF1330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1330
CMS1_k127_2967067_3	1429916.X566_04370	9.002e-153	486.0	COG0625@1|root,COG0625@2|Bacteria,1MUN3@1224|Proteobacteria,2TTDF@28211|Alphaproteobacteria,3JTWQ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Glutathione S-transferase, C-terminal domain	MA20_16405	-	-	ko:K11209	-	-	-	-	ko00000,ko01000	-	-	-	GST_C,GST_C_2,GST_N
CMS1_k127_2967067_4	745014.OMB55_00023870	6.48e-99	338.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1RYRB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS1_k127_2967067_6	279238.Saro_1072	2.086e-76	261.0	COG1309@1|root,COG1309@2|Bacteria,1MX0H@1224|Proteobacteria,2U08M@28211|Alphaproteobacteria,2K454@204457|Sphingomonadales	204457|Sphingomonadales	K	Transcriptional regulator, TetR, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_9,TetR_N
CMS1_k127_2967067_7	1248760.ANFZ01000009_gene1037	1.58e-71	243.0	COG1024@1|root,COG1024@2|Bacteria,1MVPQ@1224|Proteobacteria,2TTJ4@28211|Alphaproteobacteria,2K20K@204457|Sphingomonadales	204457|Sphingomonadales	I	enoyl-CoA hydratase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS1_k127_2999439_4	1247963.JPHU01000004_gene471	3.705e-125	410.0	COG1960@1|root,COG1960@2|Bacteria,1MUBH@1224|Proteobacteria,2TVBB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	acyl-CoA dehydrogenase	MA20_22775	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS1_k127_2999439_1	1247963.JPHU01000004_gene475	1.522e-149	482.0	COG1960@1|root,COG1960@2|Bacteria,1MVJC@1224|Proteobacteria,2TUVB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	acyl-CoA dehydrogenase	MA20_22780	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS1_k127_2999439_2	1382303.JPOM01000001_gene31	4.516e-141	471.0	COG2130@1|root,COG2130@2|Bacteria,1MUC2@1224|Proteobacteria,2TQYM@28211|Alphaproteobacteria,2KGBE@204458|Caulobacterales	204458|Caulobacterales	S	N-terminal domain of oxidoreductase	-	-	-	ko:K07119	-	-	-	-	ko00000	-	-	-	ADH_N_2,ADH_zinc_N
CMS1_k127_2999439_8	1380394.JADL01000001_gene1965	6.745e-66	233.0	COG0491@1|root,COG0491@2|Bacteria,1PHBX@1224|Proteobacteria,2TVDN@28211|Alphaproteobacteria,2JWC2@204441|Rhodospirillales	204441|Rhodospirillales	S	Metallo-beta-lactamase superfamily	-	-	3.1.1.81	ko:K13075	ko02024,map02024	-	R08970	RC00713	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
CMS1_k127_2999439_5	1550073.JROH01000017_gene395	6.637e-117	384.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,2TUYZ@28211|Alphaproteobacteria,2K222@204457|Sphingomonadales	204457|Sphingomonadales	C	Pyruvate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	E1_dh
CMS1_k127_2999439_3	1550073.JROH01000017_gene394	1.161e-128	419.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,2TRFK@28211|Alphaproteobacteria,2K13C@204457|Sphingomonadales	204457|Sphingomonadales	C	Transketolase, pyrimidine binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Transket_pyr,Transketolase_C
CMS1_k127_2999439_11	46429.BV95_02497	3.718e-24	104.0	COG0508@1|root,COG0508@2|Bacteria,1NNHT@1224|Proteobacteria,2UMCP@28211|Alphaproteobacteria,2K6YW@204457|Sphingomonadales	204457|Sphingomonadales	C	Biotin-requiring enzyme	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_lipoyl
CMS1_k127_2999439_6	1545915.JROG01000009_gene2647	1.888e-104	345.0	COG2197@1|root,COG2197@2|Bacteria,1R6UF@1224|Proteobacteria,2TU0V@28211|Alphaproteobacteria,2K2AM@204457|Sphingomonadales	204457|Sphingomonadales	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
CMS1_k127_2999439_9	383381.EH30_15690	7.935e-35	138.0	COG2050@1|root,COG2050@2|Bacteria,1N180@1224|Proteobacteria,2UCK4@28211|Alphaproteobacteria,2K7XG@204457|Sphingomonadales	204457|Sphingomonadales	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
CMS1_k127_2999439_0	383381.EH30_10190	2.946e-188	602.0	COG4638@1|root,COG4638@2|Bacteria,1R4IX@1224|Proteobacteria,2U0IQ@28211|Alphaproteobacteria,2K1CE@204457|Sphingomonadales	204457|Sphingomonadales	P	Rieske 2Fe-2S	-	-	-	-	-	-	-	-	-	-	-	-	Rieske,Ring_hydroxyl_A
CMS1_k127_2999439_7	383381.EH30_15745	3.964e-77	265.0	COG0625@1|root,COG0625@2|Bacteria,1Q05U@1224|Proteobacteria,2TTDK@28211|Alphaproteobacteria,2K5H6@204457|Sphingomonadales	204457|Sphingomonadales	O	Glutathione S-transferase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	GST_C,GST_N_3
CMS1_k127_2999439_10	748247.AZKH_2297	7.551e-31	123.0	COG0346@1|root,COG0346@2|Bacteria,1MWHG@1224|Proteobacteria,2VJM7@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_4
CMS1_k127_3041919_7	314225.ELI_06020	7.347e-14	71.0	COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,2U5V2@28211|Alphaproteobacteria,2K3XC@204457|Sphingomonadales	204457|Sphingomonadales	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
CMS1_k127_3041919_5	316056.RPC_2562	2.518e-46	170.0	COG0233@1|root,COG0233@2|Bacteria,1Q3ZU@1224|Proteobacteria,2UBAE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Sensors of blue-light using FAD	-	-	-	-	-	-	-	-	-	-	-	-	BLUF
CMS1_k127_3041919_3	1248917.ANFX01000040_gene798	1.177e-101	337.0	COG1028@1|root,COG1028@2|Bacteria,1MWJI@1224|Proteobacteria,2TRNJ@28211|Alphaproteobacteria,2K382@204457|Sphingomonadales	204457|Sphingomonadales	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS1_k127_3041919_4	627192.SLG_21420	2.818e-47	176.0	COG1695@1|root,COG1695@2|Bacteria,1RHSE@1224|Proteobacteria,2U1HF@28211|Alphaproteobacteria,2K4SR@204457|Sphingomonadales	204457|Sphingomonadales	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	PadR
CMS1_k127_3041919_0	1088721.NSU_2646	4.276e-208	655.0	COG2610@1|root,COG2610@2|Bacteria,1N2VU@1224|Proteobacteria,2TV53@28211|Alphaproteobacteria,2K4XZ@204457|Sphingomonadales	204457|Sphingomonadales	EG	H gluconate symporter	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3041919_1	685035.ADAE01000018_gene704	9.836e-179	567.0	2DC9S@1|root,2ZDD0@2|Bacteria,1R9FC@1224|Proteobacteria,2TU5E@28211|Alphaproteobacteria,2K25Q@204457|Sphingomonadales	204457|Sphingomonadales	S	Indoleamine 2,3-dioxygenase	-	-	1.13.11.52	ko:K00463	ko00380,ko01100,ko05143,map00380,map01100,map05143	M00038	R00678,R02702,R02909,R03628	RC00356	ko00000,ko00001,ko00002,ko01000	-	-	-	IDO
CMS1_k127_3041919_6	685035.ADAE01000018_gene703	5.226e-26	113.0	2CEAH@1|root,2ZNQH@2|Bacteria,1NQDW@1224|Proteobacteria,2UKRU@28211|Alphaproteobacteria,2K860@204457|Sphingomonadales	204457|Sphingomonadales	S	Glycine zipper	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3041919_2	1537715.JQFJ01000002_gene1413	4.509e-174	557.0	COG0534@1|root,COG0534@2|Bacteria,1MUAM@1224|Proteobacteria,2TSDU@28211|Alphaproteobacteria,2K152@204457|Sphingomonadales	204457|Sphingomonadales	V	Na -driven multidrug efflux pump	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
CMS1_k127_3048626_11	629773.AORY01000004_gene359	2.372e-39	151.0	COG2334@1|root,COG2334@2|Bacteria,1MUKJ@1224|Proteobacteria,2TS6D@28211|Alphaproteobacteria,2K09Q@204457|Sphingomonadales	204457|Sphingomonadales	F	Belongs to the pseudomonas-type ThrB family	thrB	-	2.7.1.39	ko:K02204	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	APH
CMS1_k127_3048626_2	1248760.ANFZ01000006_gene2388	1.177e-151	485.0	COG0761@1|root,COG0761@2|Bacteria,1MU7G@1224|Proteobacteria,2TRNR@28211|Alphaproteobacteria,2K1ES@204457|Sphingomonadales	204457|Sphingomonadales	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
CMS1_k127_3048626_8	1537715.JQFJ01000002_gene303	2.604e-73	253.0	2B5IK@1|root,31YDD@2|Bacteria,1RAZF@1224|Proteobacteria,2U6F0@28211|Alphaproteobacteria,2K43H@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3048626_1	1123270.ATUR01000002_gene2446	2.364e-277	861.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,2TS3Y@28211|Alphaproteobacteria,2K0G5@204457|Sphingomonadales	204457|Sphingomonadales	J	Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1,tRNA-synt_1d,tRNA-synt_1f
CMS1_k127_3048626_10	1537715.JQFJ01000002_gene305	1.776e-48	181.0	COG3115@1|root,COG3115@2|Bacteria,1RJNQ@1224|Proteobacteria,2UC30@28211|Alphaproteobacteria,2K2NX@204457|Sphingomonadales	204457|Sphingomonadales	D	Sporulation related domain	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
CMS1_k127_3048626_3	314225.ELI_01580	1.974e-149	479.0	COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,2TRJK@28211|Alphaproteobacteria,2JZUV@204457|Sphingomonadales	204457|Sphingomonadales	G	beta-N-acetylhexosaminidase	nagZ	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
CMS1_k127_3048626_5	1123269.NX02_00075	2.565e-99	331.0	COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,2TS1V@28211|Alphaproteobacteria,2K15W@204457|Sphingomonadales	204457|Sphingomonadales	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
CMS1_k127_3048626_7	1081640.AGFU01000079_gene3389	3.805e-82	279.0	COG1386@1|root,COG1386@2|Bacteria,1PUA6@1224|Proteobacteria,2TU64@28211|Alphaproteobacteria,2K231@204457|Sphingomonadales	204457|Sphingomonadales	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
CMS1_k127_3048626_13	1123270.ATUR01000002_gene2452	1.845e-19	90.0	COG1826@1|root,COG1826@2|Bacteria,1NGDP@1224|Proteobacteria,2UFBN@28211|Alphaproteobacteria,2K6TA@204457|Sphingomonadales	204457|Sphingomonadales	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
CMS1_k127_3048626_12	1123270.ATUR01000002_gene2453	2.355e-28	117.0	COG1826@1|root,COG1826@2|Bacteria,1N73F@1224|Proteobacteria,2UF4Z@28211|Alphaproteobacteria,2K60Q@204457|Sphingomonadales	204457|Sphingomonadales	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation	tatB	-	-	ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
CMS1_k127_3048626_4	1123270.ATUR01000002_gene2454	1.325e-109	359.0	COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,2TTIX@28211|Alphaproteobacteria,2K1PD@204457|Sphingomonadales	204457|Sphingomonadales	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
CMS1_k127_3048626_0	1545915.JROG01000003_gene1346	1.527e-277	871.0	COG1629@1|root,COG4771@2|Bacteria,1QTS8@1224|Proteobacteria,2TW3Y@28211|Alphaproteobacteria,2KEA5@204457|Sphingomonadales	204457|Sphingomonadales	P	COG1629 Outer membrane receptor proteins, mostly Fe transport	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
CMS1_k127_3048626_9	1030157.AFMP01000032_gene495	1.586e-66	231.0	COG2764@1|root,COG2764@2|Bacteria,1RF5T@1224|Proteobacteria,2U922@28211|Alphaproteobacteria,2K6UN@204457|Sphingomonadales	204457|Sphingomonadales	S	Glyoxalase-like domain	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	Glyoxalase
CMS1_k127_3048626_6	1479239.JQMU01000001_gene1854	1.709e-84	286.0	COG0027@1|root,COG0027@2|Bacteria,1N3KA@1224|Proteobacteria,2TVIF@28211|Alphaproteobacteria,2K0X5@204457|Sphingomonadales	204457|Sphingomonadales	F	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate	purT	-	2.1.2.2	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
CMS1_k127_3120419_6	317655.Sala_0484	1.328e-83	282.0	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,2TU0C@28211|Alphaproteobacteria,2K329@204457|Sphingomonadales	204457|Sphingomonadales	P	Sodium:sulfate symporter transmembrane region	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
CMS1_k127_3120419_5	1030157.AFMP01000050_gene17	7.495e-98	326.0	COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,2TTXU@28211|Alphaproteobacteria,2K13X@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the multicopper oxidase YfiH RL5 family	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
CMS1_k127_3120419_0	1123270.ATUR01000004_gene1763	0.0	1130.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,2TRUM@28211|Alphaproteobacteria,2K072@204457|Sphingomonadales	204457|Sphingomonadales	E	aminopeptidase N	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,DUF3458_C,Peptidase_M1
CMS1_k127_3120419_1	1088721.NSU_1829	3.948e-166	535.0	COG0501@1|root,COG0501@2|Bacteria,1MUXT@1224|Proteobacteria,2TVI9@28211|Alphaproteobacteria,2K2GU@204457|Sphingomonadales	204457|Sphingomonadales	O	CAAX prenyl protease N-terminal, five membrane helices	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
CMS1_k127_3120419_3	1192759.AKIB01000072_gene604	2.616e-110	362.0	COG0451@1|root,COG0451@2|Bacteria,1MWVJ@1224|Proteobacteria,2TRDY@28211|Alphaproteobacteria,2K1E4@204457|Sphingomonadales	204457|Sphingomonadales	GM	epimerase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3120419_4	291985.CCSI01000002_gene1343	4.6e-104	347.0	COG0697@1|root,COG0697@2|Bacteria,1MXJY@1224|Proteobacteria,2TVBG@28211|Alphaproteobacteria,2K0J7@204457|Sphingomonadales	204457|Sphingomonadales	EG	Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS1_k127_3120419_2	1550073.JROH01000007_gene1852	5.876e-147	473.0	COG2008@1|root,COG2008@2|Bacteria,1MWCR@1224|Proteobacteria,2TSUA@28211|Alphaproteobacteria,2K0EJ@204457|Sphingomonadales	204457|Sphingomonadales	E	Threonine aldolase	ltaA	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
CMS1_k127_3120419_7	398720.MED217_07616	7.169e-33	134.0	COG2335@1|root,COG2335@2|Bacteria,4NMAH@976|Bacteroidetes,1I224@117743|Flavobacteriia,2XJAD@283735|Leeuwenhoekiella	976|Bacteroidetes	M	Four repeated domains in the Fasciclin I family of proteins, present in many other contexts.	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
CMS1_k127_3170550_0	1123270.ATUR01000006_gene9	3.786e-208	655.0	COG0477@1|root,COG2814@2|Bacteria,1MUZ8@1224|Proteobacteria,2TTD2@28211|Alphaproteobacteria,2K1E8@204457|Sphingomonadales	204457|Sphingomonadales	EGP	Major facilitator superfamily	-	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	MFS_1
CMS1_k127_3170550_3	1545915.JROG01000004_gene2049	2.794e-66	234.0	COG5429@1|root,COG5429@2|Bacteria,1MW6R@1224|Proteobacteria,2U33F@28211|Alphaproteobacteria,2K4W4@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF1223)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1223
CMS1_k127_3170550_1	1114964.L485_20770	5.744e-110	362.0	COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,2TQP2@28211|Alphaproteobacteria,2K0YS@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
CMS1_k127_3170550_2	1219035.NT2_02_04070	6.108e-74	253.0	COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,2U70Y@28211|Alphaproteobacteria,2K3X3@204457|Sphingomonadales	204457|Sphingomonadales	L	Methyltransferase	-	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
CMS1_k127_3241617_2	1123270.ATUR01000002_gene2216	1.646e-38	144.0	COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,2TT3I@28211|Alphaproteobacteria,2K0XU@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
CMS1_k127_3241617_0	1248760.ANFZ01000006_gene2750	1.741e-98	327.0	COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,2TS0N@28211|Alphaproteobacteria,2K0TB@204457|Sphingomonadales	204457|Sphingomonadales	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
CMS1_k127_3241617_1	1174684.EBMC1_11535	2.188e-77	274.0	COG4935@1|root,COG4935@2|Bacteria,1RK8D@1224|Proteobacteria,2UKHW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,P_proprotein
CMS1_k127_3247305_6	279238.Saro_1005	4.973e-32	126.0	COG3814@1|root,COG3814@2|Bacteria,1N1FE@1224|Proteobacteria,2U7H9@28211|Alphaproteobacteria,2K35H@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	ko:K09985	-	-	-	-	ko00000	-	-	-	SspB
CMS1_k127_3247305_0	1112214.AHIS01000009_gene153	3.32e-206	650.0	COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,2TQM7@28211|Alphaproteobacteria,2K0K7@204457|Sphingomonadales	204457|Sphingomonadales	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
CMS1_k127_3247305_7	1545915.JROG01000003_gene995	3.329e-07	55.0	2A1V0@1|root,30Q45@2|Bacteria,1Q73G@1224|Proteobacteria,2VD7M@28211|Alphaproteobacteria,2KB42@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3247305_4	1123288.SOV_3c00910	8.97e-42	170.0	COG2271@1|root,COG2271@2|Bacteria,1TRHT@1239|Firmicutes,4H66F@909932|Negativicutes	909932|Negativicutes	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_3247305_3	1231185.BAMP01000003_gene4495	5.368e-69	257.0	COG0628@1|root,COG0628@2|Bacteria,1MXXU@1224|Proteobacteria,2TQJJ@28211|Alphaproteobacteria,43HMQ@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
CMS1_k127_3247305_2	1088721.NSU_1034	5.943e-88	303.0	COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,2TSCQ@28211|Alphaproteobacteria,2K16A@204457|Sphingomonadales	204457|Sphingomonadales	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
CMS1_k127_3247305_8	383381.EH30_07795	4.662e-05	53.0	2AIVA@1|root,30KTM@2|Bacteria,1P94R@1224|Proteobacteria,2VGUJ@28211|Alphaproteobacteria,2KE6F@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3247305_5	1127673.GLIP_3797	1.539e-37	149.0	COG0457@1|root,COG0457@2|Bacteria,1N9D5@1224|Proteobacteria,1SAKR@1236|Gammaproteobacteria,46B30@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3247305_1	102129.Lepto7375DRAFT_0414	1.198e-96	337.0	COG2072@1|root,COG2072@2|Bacteria,1GBHZ@1117|Cyanobacteria	1117|Cyanobacteria	P	flavoprotein involved in K transport	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3252134_2	1123270.ATUR01000006_gene64	1.236e-48	174.0	COG0714@1|root,COG0714@2|Bacteria,1MV5I@1224|Proteobacteria,2TRI8@28211|Alphaproteobacteria,2JZXF@204457|Sphingomonadales	204457|Sphingomonadales	S	ATPase AAA	-	-	-	-	-	-	-	-	-	-	-	-	AAA
CMS1_k127_3252134_0	161528.ED21_27348	3.231e-225	702.0	COG3825@1|root,COG3825@2|Bacteria,1MUAJ@1224|Proteobacteria,2TS5P@28211|Alphaproteobacteria,2K0XS@204457|Sphingomonadales	204457|Sphingomonadales	S	Von Willebrand factor A	-	-	-	ko:K09989	-	-	-	-	ko00000	-	-	-	VWA_CoxE
CMS1_k127_3252134_3	685778.AORL01000004_gene3596	9.049e-32	126.0	2BJDS@1|root,32DQ3@2|Bacteria,1NWA6@1224|Proteobacteria,2USD6@28211|Alphaproteobacteria,2K649@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3252134_1	1248760.ANFZ01000021_gene397	1.796e-214	671.0	COG3876@1|root,COG3876@2|Bacteria,1MX3S@1224|Proteobacteria,2U1KM@28211|Alphaproteobacteria,2K0PB@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF1343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
CMS1_k127_3252134_4	317655.Sala_1647	1.759e-14	73.0	2C0PI@1|root,32VVI@2|Bacteria,1N1H7@1224|Proteobacteria,2UE1P@28211|Alphaproteobacteria,2K60G@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3298572_3	1044.EH31_05745	2.489e-100	329.0	COG1960@1|root,COG1960@2|Bacteria,1MU2V@1224|Proteobacteria,2TSK3@28211|Alphaproteobacteria,2JZVP@204457|Sphingomonadales	204457|Sphingomonadales	I	acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS1_k127_3298572_0	1537715.JQFJ01000002_gene2151	5.565e-202	632.0	COG1062@1|root,COG1062@2|Bacteria,1MUK4@1224|Proteobacteria,2TU1G@28211|Alphaproteobacteria,2K0RB@204457|Sphingomonadales	204457|Sphingomonadales	C	alcohol dehydrogenase	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_3298572_1	1248760.ANFZ01000009_gene1204	4.925e-166	528.0	COG3173@1|root,COG3173@2|Bacteria,1MWAK@1224|Proteobacteria,2TT2N@28211|Alphaproteobacteria,2K142@204457|Sphingomonadales	204457|Sphingomonadales	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS1_k127_3298572_2	1545915.JROG01000003_gene1007	4.913e-111	364.0	COG1028@1|root,COG1028@2|Bacteria,1MU3W@1224|Proteobacteria,2TT5X@28211|Alphaproteobacteria,2K05I@204457|Sphingomonadales	204457|Sphingomonadales	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS1_k127_3298572_5	1248760.ANFZ01000006_gene2807	1.309e-27	120.0	2AYNJ@1|root,31QT2@2|Bacteria,1NJKX@1224|Proteobacteria,2UKM1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3298572_4	1174684.EBMC1_02860	1.265e-31	130.0	2BR1E@1|root,32JYX@2|Bacteria,1N0ZU@1224|Proteobacteria,2UCNA@28211|Alphaproteobacteria,2K78B@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3298572_6	1123270.ATUR01000003_gene1165	1.704e-15	76.0	COG1505@1|root,COG1505@2|Bacteria,1NZ7N@1224|Proteobacteria,2TW70@28211|Alphaproteobacteria,2K10C@204457|Sphingomonadales	204457|Sphingomonadales	E	Prolyl oligopeptidase	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
CMS1_k127_3299253_4	1379701.JPJC01000057_gene3235	5.072e-108	357.0	COG3555@1|root,COG3555@2|Bacteria,1MW3M@1224|Proteobacteria,2U5YV@28211|Alphaproteobacteria,2K07E@204457|Sphingomonadales	204457|Sphingomonadales	O	Aspartyl/Asparaginyl beta-hydroxylase	-	-	-	ko:K12979	-	-	-	-	ko00000,ko01000,ko01005	-	-	-	Asp_Arg_Hydrox
CMS1_k127_3299253_7	627192.SLG_06180	5.171e-61	217.0	COG1376@1|root,COG1376@2|Bacteria,1RG34@1224|Proteobacteria,2U7XX@28211|Alphaproteobacteria,2K4WP@204457|Sphingomonadales	204457|Sphingomonadales	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
CMS1_k127_3299253_0	1280953.HOC_10389	9.933e-283	879.0	COG4805@1|root,COG4805@2|Bacteria,1R5EP@1224|Proteobacteria,2U119@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
CMS1_k127_3299253_3	1248760.ANFZ01000006_gene2532	2.802e-161	518.0	COG0477@1|root,COG2814@2|Bacteria,1QTX0@1224|Proteobacteria,2TUM5@28211|Alphaproteobacteria,2K1MY@204457|Sphingomonadales	204457|Sphingomonadales	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
CMS1_k127_3299253_2	1112212.JH584235_gene3827	2.517e-167	529.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,2TS33@28211|Alphaproteobacteria,2K2A3@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS1_k127_3299253_6	1144305.PMI02_03104	1.226e-69	244.0	COG0412@1|root,COG0412@2|Bacteria,1RJ0Q@1224|Proteobacteria,2UBJ9@28211|Alphaproteobacteria,2KDGK@204457|Sphingomonadales	204457|Sphingomonadales	Q	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH
CMS1_k127_3299253_8	1545915.JROG01000004_gene2321	5.155e-11	66.0	2ASV1@1|root,31IAF@2|Bacteria,1PBMX@1224|Proteobacteria,2UXU2@28211|Alphaproteobacteria,2KBK9@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3299253_5	634452.APA01_02500	7.01e-83	283.0	COG3555@1|root,COG3555@2|Bacteria,1MW3M@1224|Proteobacteria,2TRVQ@28211|Alphaproteobacteria,2JWQC@204441|Rhodospirillales	204441|Rhodospirillales	O	Aspartyl/Asparaginyl beta-hydroxylase	-	-	-	ko:K12979	-	-	-	-	ko00000,ko01000,ko01005	-	-	-	Asp_Arg_Hydrox
CMS1_k127_3299253_1	1248760.ANFZ01000004_gene1896	1.436e-169	537.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,2TQJS@28211|Alphaproteobacteria,2K0RG@204457|Sphingomonadales	204457|Sphingomonadales	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
CMS1_k127_3308916_10	1545915.JROG01000004_gene2076	5.067e-40	149.0	COG3182@1|root,COG3182@2|Bacteria,1MW2S@1224|Proteobacteria,2TSFC@28211|Alphaproteobacteria,2K0G4@204457|Sphingomonadales	204457|Sphingomonadales	S	PepSY-associated TM region	-	-	-	-	-	-	-	-	-	-	-	-	PepSY_TM
CMS1_k127_3308916_4	1479239.JQMU01000001_gene906	5.627e-126	410.0	COG0730@1|root,COG0730@2|Bacteria,1RBW3@1224|Proteobacteria,2UAUV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	-	-	-	-	-	-	-	-	-	TauE
CMS1_k127_3308916_1	1123269.NX02_28500	4.342e-205	655.0	COG0115@1|root,COG0147@1|root,COG0115@2|Bacteria,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,2TUBY@28211|Alphaproteobacteria,2K1FB@204457|Sphingomonadales	204457|Sphingomonadales	EH	component I	pabB	-	2.6.1.85,4.1.3.38	ko:K01665,ko:K03342	ko00790,map00790	-	R01716,R05553	RC00010,RC01418,RC01843,RC02148	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4,Anth_synt_I_N,Chorismate_bind
CMS1_k127_3308916_0	1545915.JROG01000003_gene1271	2.048e-258	811.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,2TUBW@28211|Alphaproteobacteria,2K2WB@204457|Sphingomonadales	204457|Sphingomonadales	EU	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
CMS1_k127_3308916_9	394221.Mmar10_0333	2.476e-41	156.0	COG2197@1|root,COG2197@2|Bacteria,1N0NK@1224|Proteobacteria,2UCCE@28211|Alphaproteobacteria,43YHN@69657|Hyphomonadaceae	28211|Alphaproteobacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
CMS1_k127_3308916_8	366602.Caul_1534	4.327e-43	163.0	2CB8S@1|root,30PE6@2|Bacteria,1RG91@1224|Proteobacteria,2U7BM@28211|Alphaproteobacteria,2KGWR@204458|Caulobacterales	204458|Caulobacterales	S	Protein of unknown function (DUF4199)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4199
CMS1_k127_3308916_7	867900.Celly_1008	1.013e-48	176.0	COG0346@1|root,COG0346@2|Bacteria,4NQIE@976|Bacteroidetes,1I2UJ@117743|Flavobacteriia	976|Bacteroidetes	E	glyoxalase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS1_k127_3308916_6	1280950.HJO_13401	4.114e-66	232.0	COG1024@1|root,COG1024@2|Bacteria,1RAAV@1224|Proteobacteria,2UB9Y@28211|Alphaproteobacteria,43Y8B@69657|Hyphomonadaceae	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase isomerase family protein	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS1_k127_3308916_2	1449076.JOOE01000004_gene286	7.76e-146	475.0	COG0520@1|root,COG0520@2|Bacteria,1Q7AQ@1224|Proteobacteria,2VCMD@28211|Alphaproteobacteria,2K2Q9@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
CMS1_k127_3308916_3	1545915.JROG01000009_gene2778	3.508e-128	417.0	COG3483@1|root,COG3483@2|Bacteria,1MW68@1224|Proteobacteria,2TRXV@28211|Alphaproteobacteria,2K1B3@204457|Sphingomonadales	204457|Sphingomonadales	E	Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety	kynA	GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.13.11.11	ko:K00453	ko00380,ko01100,map00380,map01100	M00038	R00678	RC00356	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_dioxygenase
CMS1_k127_3308916_5	1545915.JROG01000007_gene3093	5.215e-90	298.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2TRMU@28211|Alphaproteobacteria,2K09N@204457|Sphingomonadales	204457|Sphingomonadales	NU	General secretion pathway protein E	gspE	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
CMS1_k127_3330900_2	1088721.NSU_2616	2.519e-134	432.0	COG3853@1|root,COG3853@2|Bacteria,1MY18@1224|Proteobacteria,2TU4T@28211|Alphaproteobacteria,2K07G@204457|Sphingomonadales	204457|Sphingomonadales	P	Toxic anion resistance	-	-	-	-	-	-	-	-	-	-	-	-	TelA
CMS1_k127_3330900_8	1537715.JQFJ01000002_gene1200	5.533e-71	247.0	COG2755@1|root,COG2755@2|Bacteria,1RCXZ@1224|Proteobacteria,2U74E@28211|Alphaproteobacteria,2K1U9@204457|Sphingomonadales	204457|Sphingomonadales	E	COG2755 Lysophospholipase L1 and related esterases	-	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL_2
CMS1_k127_3330900_5	1545915.JROG01000001_gene453	4.819e-96	320.0	COG4181@1|root,COG4181@2|Bacteria,1MXG9@1224|Proteobacteria,2TS0J@28211|Alphaproteobacteria,2JZZV@204457|Sphingomonadales	204457|Sphingomonadales	Q	ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_3330900_1	317655.Sala_0698	1.271e-306	961.0	COG3127@1|root,COG3127@2|Bacteria,1MU9R@1224|Proteobacteria,2TS8V@28211|Alphaproteobacteria,2K03T@204457|Sphingomonadales	204457|Sphingomonadales	Q	ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS1_k127_3330900_6	1123270.ATUR01000004_gene1650	8.483e-94	326.0	COG0385@1|root,COG0385@2|Bacteria,1MUMM@1224|Proteobacteria,2TU7J@28211|Alphaproteobacteria,2K0HH@204457|Sphingomonadales	204457|Sphingomonadales	S	Bile acid sodium symporter	-	-	-	ko:K14347	-	-	-	-	ko00000,ko02000,ko04147	2.A.93.1	-	-	SBF_like
CMS1_k127_3330900_0	314266.SKA58_14842	3.156e-319	985.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,2TR63@28211|Alphaproteobacteria,2K169@204457|Sphingomonadales	204457|Sphingomonadales	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
CMS1_k127_3330900_4	1545915.JROG01000003_gene1675	1.256e-96	323.0	COG3637@1|root,COG3637@2|Bacteria,1R7V6@1224|Proteobacteria,2U1FW@28211|Alphaproteobacteria,2K1I1@204457|Sphingomonadales	204457|Sphingomonadales	M	Outer membrane protein beta-barrel domain	-	-	-	ko:K16079	-	-	-	-	ko00000,ko02000	1.B.4.2.1	-	-	OMP_b-brl
CMS1_k127_3330900_10	1545915.JROG01000003_gene1673	7.792e-40	149.0	2CC0C@1|root,32RUG@2|Bacteria,1MZVQ@1224|Proteobacteria,2UBWU@28211|Alphaproteobacteria,2K606@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF3297)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3297
CMS1_k127_3330900_11	383381.EH30_03065	4.168e-29	120.0	2CIZA@1|root,32S8U@2|Bacteria,1N29D@1224|Proteobacteria,2UEH4@28211|Alphaproteobacteria,2KATK@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3330900_3	1282876.BAOK01000001_gene3532	1.865e-111	367.0	COG0300@1|root,COG0300@2|Bacteria,1R7MT@1224|Proteobacteria,2TXPY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS1_k127_3330900_7	1248760.ANFZ01000008_gene1614	2.644e-90	307.0	COG1024@1|root,COG1024@2|Bacteria,1N4N7@1224|Proteobacteria,2TS6T@28211|Alphaproteobacteria,2K1V0@204457|Sphingomonadales	204457|Sphingomonadales	I	enoyl-CoA hydratase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS1_k127_3330900_9	1280949.HAD_05380	8.86e-64	220.0	COG0346@1|root,COG0346@2|Bacteria,1N4DA@1224|Proteobacteria,2UEPZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Glyoxalase_4
CMS1_k127_3368187_0	1123270.ATUR01000007_gene1309	1.293e-311	963.0	COG1410@1|root,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,2TQTG@28211|Alphaproteobacteria,2K0JK@204457|Sphingomonadales	204457|Sphingomonadales	E	5-methyltetrahydrofolate--homocysteine methyltransferase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind
CMS1_k127_3368187_1	392499.Swit_2398	3.896e-13	73.0	COG3420@1|root,COG3420@2|Bacteria,1R5QH@1224|Proteobacteria,2U3Y9@28211|Alphaproteobacteria,2K0EA@204457|Sphingomonadales	204457|Sphingomonadales	P	alginic acid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
CMS1_k127_3382172_0	1123270.ATUR01000004_gene1611	8.537e-103	341.0	COG4221@1|root,COG4221@2|Bacteria,1RAKI@1224|Proteobacteria,2TUJT@28211|Alphaproteobacteria,2K29E@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS1_k127_3382172_3	314266.SKA58_13473	9.555e-34	133.0	COG2154@1|root,COG2154@2|Bacteria,1MZ5Q@1224|Proteobacteria,2UBWN@28211|Alphaproteobacteria,2K5VW@204457|Sphingomonadales	204457|Sphingomonadales	H	pterin-4-alpha-carbinolamine dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
CMS1_k127_3382172_2	745310.G432_14315	8.798e-55	198.0	COG4133@1|root,COG4133@2|Bacteria,1MZPC@1224|Proteobacteria,2TVBT@28211|Alphaproteobacteria,2K5BJ@204457|Sphingomonadales	204457|Sphingomonadales	O	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system	ccmA	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
CMS1_k127_3382172_1	1030157.AFMP01000040_gene1395	1.016e-69	243.0	COG2386@1|root,COG2386@2|Bacteria,1NJB0@1224|Proteobacteria,2TUSG@28211|Alphaproteobacteria,2K43Z@204457|Sphingomonadales	204457|Sphingomonadales	O	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmB	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
CMS1_k127_3382172_4	78245.Xaut_3042	1.939e-31	131.0	COG3615@1|root,COG3615@2|Bacteria,1N0H2@1224|Proteobacteria,2UBVD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Domain of unknown function (DUF1971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1971
CMS1_k127_3382172_5	1122970.AUHC01000001_gene663	9.225e-15	78.0	29DVJ@1|root,300TG@2|Bacteria,1P28D@1224|Proteobacteria,2UV6W@28211|Alphaproteobacteria,2K7B6@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3387584_2	1123269.NX02_22505	1.562e-45	170.0	COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,2TR79@28211|Alphaproteobacteria,2K19H@204457|Sphingomonadales	204457|Sphingomonadales	H	Belongs to the FPP GGPP synthase family	ispA	-	2.5.1.1,2.5.1.10	ko:K00795	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364	R01658,R02003	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
CMS1_k127_3387584_3	685035.ADAE01000018_gene596	4.145e-21	95.0	COG1722@1|root,COG1722@2|Bacteria,1PTYQ@1224|Proteobacteria,2UFD6@28211|Alphaproteobacteria,2K6WZ@204457|Sphingomonadales	204457|Sphingomonadales	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
CMS1_k127_3387584_0	517722.AEUE01000006_gene1932	7.238e-81	274.0	arCOG09454@1|root,30G4A@2|Bacteria,1N61J@1224|Proteobacteria,2UEFT@28211|Alphaproteobacteria,2K4KH@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3387584_1	1044.EH31_01230	9.543e-46	174.0	COG4852@1|root,COG4852@2|Bacteria,1MZHP@1224|Proteobacteria,2UBSF@28211|Alphaproteobacteria,2K61I@204457|Sphingomonadales	204457|Sphingomonadales	S	Predicted membrane protein (DUF2177)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2177
CMS1_k127_3387584_4	1211777.BN77_3103	1.993e-12	68.0	COG3313@1|root,COG3313@2|Bacteria,1NGD5@1224|Proteobacteria,2UUF7@28211|Alphaproteobacteria,4BG7V@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1289)	-	-	-	ko:K06938	-	-	-	-	ko00000	-	-	-	DUF1289
CMS1_k127_3390053_5	1248760.ANFZ01000019_gene1776	4.859e-101	342.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,2TR48@28211|Alphaproteobacteria,2K02P@204457|Sphingomonadales	204457|Sphingomonadales	D	DNA segregation ATPase FtsK SpoIIIE	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
CMS1_k127_3390053_4	1502850.FG91_03408	9.15e-152	492.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,2TRZU@28211|Alphaproteobacteria,2JZY3@204457|Sphingomonadales	204457|Sphingomonadales	CH	Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family	-	-	-	ko:K03185	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04989,R08773	RC02670	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
CMS1_k127_3390053_7	1313172.YM304_13640	1.715e-93	313.0	COG1028@1|root,COG1028@2|Bacteria,2GPNY@201174|Actinobacteria	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS1_k127_3390053_6	1248760.ANFZ01000002_gene2982	6.109e-97	322.0	COG2885@1|root,COG2885@2|Bacteria,1MYBP@1224|Proteobacteria,2U787@28211|Alphaproteobacteria,2K074@204457|Sphingomonadales	204457|Sphingomonadales	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_Omp,OmpA
CMS1_k127_3390053_1	1123270.ATUR01000004_gene1746	2.179e-182	580.0	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,2TS80@28211|Alphaproteobacteria,2K087@204457|Sphingomonadales	204457|Sphingomonadales	S	COG1253 Hemolysins and related proteins containing CBS domains	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
CMS1_k127_3390053_9	1545915.JROG01000009_gene2630	4.859e-32	134.0	COG3743@1|root,COG3743@2|Bacteria,1N76A@1224|Proteobacteria,2UFVP@28211|Alphaproteobacteria,2K4QR@204457|Sphingomonadales	204457|Sphingomonadales	S	rRNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HHH_5
CMS1_k127_3390053_10	1122179.KB890414_gene1882	4.297e-13	78.0	COG0823@1|root,COG2885@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,4NE6G@976|Bacteroidetes,1IPCG@117747|Sphingobacteriia	976|Bacteroidetes	MU	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,PD40,TPR_16,TPR_2,TPR_8
CMS1_k127_3390053_0	1248760.ANFZ01000004_gene1930	9.529e-198	627.0	COG0624@1|root,COG0624@2|Bacteria,1MWJS@1224|Proteobacteria,2TUHT@28211|Alphaproteobacteria,2K1MW@204457|Sphingomonadales	204457|Sphingomonadales	E	Acetylornithine deacetylase Succinyl-diaminopimelate	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
CMS1_k127_3390053_8	1112214.AHIS01000047_gene2159	2.456e-69	243.0	COG0500@1|root,COG2226@2|Bacteria,1REUM@1224|Proteobacteria,2U75Q@28211|Alphaproteobacteria,2K51Q@204457|Sphingomonadales	204457|Sphingomonadales	Q	ubiE/COQ5 methyltransferase family	-	-	-	ko:K13623	ko00564,map00564	-	R09073	RC00003,RC02308	ko00000,ko00001	-	-	-	Methyltransf_23,Methyltransf_25
CMS1_k127_3390053_3	13690.CP98_02557	2.34e-153	495.0	COG5379@1|root,COG5379@2|Bacteria,1MWG8@1224|Proteobacteria,2TQKH@28211|Alphaproteobacteria,2K195@204457|Sphingomonadales	204457|Sphingomonadales	I	S-adenosylmethionine diacylglycerol 3-amino-3-carboxypropyl transferase	-	-	-	ko:K13622	ko00564,map00564	-	R09072	RC00021,RC01091	ko00000,ko00001	-	-	-	DUF3419
CMS1_k127_3390053_2	1123270.ATUR01000005_gene518	2.826e-154	491.0	COG4277@1|root,COG4277@2|Bacteria,1MVCV@1224|Proteobacteria,2TT5U@28211|Alphaproteobacteria,2K0AV@204457|Sphingomonadales	204457|Sphingomonadales	S	DNA-binding protein with the helix-hairpin-helix motif	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3391001_0	1248760.ANFZ01000007_gene2916	9.917e-282	875.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2TR3X@28211|Alphaproteobacteria,2K0QQ@204457|Sphingomonadales	204457|Sphingomonadales	S	of ABC transporters with duplicated ATPase	-	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD
CMS1_k127_3391001_1	1248760.ANFZ01000007_gene2915	8.69e-102	338.0	COG0115@1|root,COG0115@2|Bacteria,1MVAT@1224|Proteobacteria,2TR7R@28211|Alphaproteobacteria,2K47Y@204457|Sphingomonadales	204457|Sphingomonadales	EH	D-amino acid aminotransferase	-	-	2.6.1.21	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	-	R01148,R01582,R02459,R02851,R02924,R05053	RC00006,RC00008,RC00025	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4
CMS1_k127_3391001_2	1479239.JQMU01000001_gene510	1.213e-61	220.0	COG2968@1|root,COG2968@2|Bacteria,1RH7T@1224|Proteobacteria,2U981@28211|Alphaproteobacteria,2K40S@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF541)	-	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
CMS1_k127_3391001_3	1248760.ANFZ01000007_gene2913	4.871e-28	116.0	29288@1|root,2ZPSV@2|Bacteria,1NJAG@1224|Proteobacteria,2UMCR@28211|Alphaproteobacteria,2K6S1@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PepSY
CMS1_k127_3428216_2	237727.NAP1_14713	6.545e-58	207.0	COG0625@1|root,COG0625@2|Bacteria,1RJVR@1224|Proteobacteria,2U5SU@28211|Alphaproteobacteria,2K42G@204457|Sphingomonadales	204457|Sphingomonadales	O	Glutathione S-transferase	-	-	-	-	-	-	-	-	-	-	-	-	GST_C_2,GST_C_3,GST_N_3
CMS1_k127_3428216_0	314225.ELI_10345	8.727e-119	390.0	COG1028@1|root,COG1028@2|Bacteria,1P9R4@1224|Proteobacteria,2TSIF@28211|Alphaproteobacteria,2K209@204457|Sphingomonadales	204457|Sphingomonadales	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS1_k127_3428216_1	237727.NAP1_11618	2.686e-107	352.0	COG0027@1|root,COG0027@2|Bacteria,1N3KA@1224|Proteobacteria,2TVIF@28211|Alphaproteobacteria,2K0X5@204457|Sphingomonadales	204457|Sphingomonadales	F	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate	purT	-	2.1.2.2	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
CMS1_k127_3461700_2	1007104.SUS17_2378	3.281e-171	543.0	COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,2TR6F@28211|Alphaproteobacteria,2K1W8@204457|Sphingomonadales	204457|Sphingomonadales	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
CMS1_k127_3461700_0	1122970.AUHC01000011_gene2703	8.892e-290	905.0	COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,2TQYD@28211|Alphaproteobacteria,2K20E@204457|Sphingomonadales	204457|Sphingomonadales	C	Molydopterin dinucleotide binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CMS1_k127_3461700_3	1280954.HPO_03129	3.584e-162	518.0	COG1680@1|root,COG1680@2|Bacteria,1QD0J@1224|Proteobacteria,2U189@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS1_k127_3461700_1	383381.EH30_15725	1.215e-186	587.0	COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,2TSJ5@28211|Alphaproteobacteria,2K0FW@204457|Sphingomonadales	204457|Sphingomonadales	P	Ring hydroxylating alpha subunit (catalytic domain)	-	-	-	-	-	-	-	-	-	-	-	-	Rieske,Ring_hydroxyl_A
CMS1_k127_349395_4	685778.AORL01000023_gene2093	1.11e-06	51.0	COG1225@1|root,COG1225@2|Bacteria,1RHSM@1224|Proteobacteria,2U9FF@28211|Alphaproteobacteria,2K56N@204457|Sphingomonadales	204457|Sphingomonadales	O	Peroxiredoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS1_k127_349395_3	1266998.ATUJ01000003_gene1676	3.28e-22	97.0	2E3X5@1|root,32YUB@2|Bacteria,1N766@1224|Proteobacteria,2UFVD@28211|Alphaproteobacteria,2PXWC@265|Paracoccus	28211|Alphaproteobacteria	S	Protein of unknwon function (DUF3008)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3008
CMS1_k127_349395_2	1545915.JROG01000008_gene3518	9.857e-40	164.0	COG3861@1|root,COG3861@2|Bacteria,1MZM2@1224|Proteobacteria,2UBTQ@28211|Alphaproteobacteria,2K5YD@204457|Sphingomonadales	204457|Sphingomonadales	S	PRC-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	PRC
CMS1_k127_349395_1	1120705.FG95_02247	1.549e-62	222.0	COG3871@1|root,COG3871@2|Bacteria,1RGK0@1224|Proteobacteria,2UCKT@28211|Alphaproteobacteria,2KDCT@204457|Sphingomonadales	204457|Sphingomonadales	S	Pyridoxamine 5'-phosphate oxidase like	-	-	-	-	-	-	-	-	-	-	-	-	Pyrid_ox_like
CMS1_k127_349395_0	1545915.JROG01000004_gene2078	1.672e-217	683.0	COG4773@1|root,COG4773@2|Bacteria,1NZCG@1224|Proteobacteria,2TWA3@28211|Alphaproteobacteria,2K13A@204457|Sphingomonadales	204457|Sphingomonadales	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
CMS1_k127_3508030_3	1030157.AFMP01000031_gene2927	6.172e-59	207.0	COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,2TSZE@28211|Alphaproteobacteria,2K0PS@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the TrpC family	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
CMS1_k127_3508030_0	1144305.PMI02_02187	8.695e-129	421.0	COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,2TR8S@28211|Alphaproteobacteria,2K11A@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
CMS1_k127_3508030_1	383381.EH30_06390	1.621e-103	338.0	COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,2TU3N@28211|Alphaproteobacteria,2K28N@204457|Sphingomonadales	204457|Sphingomonadales	EH	with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis	trpG	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
CMS1_k127_3508030_5	1112216.JH594425_gene1499	2.285e-26	114.0	2E9WT@1|root,3342I@2|Bacteria,1NBEH@1224|Proteobacteria,2UFGC@28211|Alphaproteobacteria,2K6FB@204457|Sphingomonadales	204457|Sphingomonadales	S	Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn)	-	-	-	-	-	-	-	-	-	-	-	-	PHA_gran_rgn
CMS1_k127_3508030_2	1297570.MESS4_580032	4.014e-63	228.0	COG0583@1|root,COG0583@2|Bacteria,1PX1B@1224|Proteobacteria,2TUE7@28211|Alphaproteobacteria,43JDB@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS1_k127_3508030_4	1449076.JOOE01000001_gene2314	8.246e-48	172.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,2TRWB@28211|Alphaproteobacteria,2K00K@204457|Sphingomonadales	204457|Sphingomonadales	E	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
CMS1_k127_3609958_2	1122137.AQXF01000003_gene1871	1.295e-42	165.0	COG0845@1|root,COG0845@2|Bacteria,1MV1T@1224|Proteobacteria,2VFH0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
CMS1_k127_3609958_1	1161401.ASJA01000006_gene1886	9.267e-73	262.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,2TSN8@28211|Alphaproteobacteria,440R6@69657|Hyphomonadaceae	28211|Alphaproteobacteria	M	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
CMS1_k127_3609958_0	383381.EH30_11780	6.97e-322	992.0	COG4774@1|root,COG4774@2|Bacteria,1NMCN@1224|Proteobacteria,2U1C8@28211|Alphaproteobacteria,2K263@204457|Sphingomonadales	204457|Sphingomonadales	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
CMS1_k127_361378_1	1123270.ATUR01000004_gene1432	2.989e-94	315.0	COG5400@1|root,COG5400@2|Bacteria,1RASG@1224|Proteobacteria,2U590@28211|Alphaproteobacteria,2K1IC@204457|Sphingomonadales	204457|Sphingomonadales	S	conserved protein UCP033924 precursor	-	-	-	-	-	-	-	-	-	-	-	-	DUF1134
CMS1_k127_361378_2	627192.SLG_36910	9.468e-87	291.0	COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,2U3RS@28211|Alphaproteobacteria,2K0MU@204457|Sphingomonadales	204457|Sphingomonadales	H	Riboflavin synthase	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
CMS1_k127_361378_0	1123270.ATUR01000004_gene1439	3.227e-114	377.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,2TR70@28211|Alphaproteobacteria,2K10R@204457|Sphingomonadales	204457|Sphingomonadales	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
CMS1_k127_361378_5	1123270.ATUR01000004_gene1440	2.358e-07	59.0	2B262@1|root,31UPC@2|Bacteria,1P55C@1224|Proteobacteria,2UX4C@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_361378_3	1550073.JROH01000001_gene564	3.482e-30	128.0	COG0810@1|root,COG0810@2|Bacteria,1NH16@1224|Proteobacteria,2UKYU@28211|Alphaproteobacteria,2K637@204457|Sphingomonadales	204457|Sphingomonadales	U	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
CMS1_k127_361378_4	1122612.AUBA01000027_gene1942	5.013e-18	83.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,2TRCI@28211|Alphaproteobacteria,2K0M4@204457|Sphingomonadales	204457|Sphingomonadales	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX2	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
CMS1_k127_3617438_2	1123270.ATUR01000003_gene890	4.004e-113	374.0	COG0144@1|root,COG0144@2|Bacteria,1MV2Q@1224|Proteobacteria,2TS6U@28211|Alphaproteobacteria,2K17G@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	-	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F
CMS1_k127_3617438_6	1545915.JROG01000003_gene1565	8.073e-47	175.0	COG0457@1|root,COG0457@2|Bacteria,1N4DV@1224|Proteobacteria,2UDFG@28211|Alphaproteobacteria,2KEE7@204457|Sphingomonadales	204457|Sphingomonadales	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14
CMS1_k127_3617438_4	1479239.JQMU01000001_gene2110	4.363e-91	309.0	COG3137@1|root,COG3137@2|Bacteria,1MWI4@1224|Proteobacteria,2UBFT@28211|Alphaproteobacteria,2KCGR@204457|Sphingomonadales	204457|Sphingomonadales	M	Protein of unknown function, DUF481	-	-	-	ko:K07283	-	-	-	-	ko00000	-	-	-	DUF481
CMS1_k127_3617438_5	452662.SJA_C1-17580	7.87e-67	233.0	COG1051@1|root,COG1051@2|Bacteria,1QU0T@1224|Proteobacteria,2TW25@28211|Alphaproteobacteria,2K4S3@204457|Sphingomonadales	204457|Sphingomonadales	F	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage	nudH	-	-	ko:K08311	ko03018,map03018	-	R10816	RC00002	ko00000,ko00001,ko01000,ko03019	-	-	-	NUDIX
CMS1_k127_3617438_3	1248760.ANFZ01000009_gene897	1.484e-104	348.0	COG0657@1|root,COG0657@2|Bacteria,1NEXK@1224|Proteobacteria,2U5X1@28211|Alphaproteobacteria,2JZVT@204457|Sphingomonadales	204457|Sphingomonadales	I	PFAM Alpha beta hydrolase fold-3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
CMS1_k127_3617438_0	745310.G432_16705	0.0	1017.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,2TU21@28211|Alphaproteobacteria,2K2JW@204457|Sphingomonadales	204457|Sphingomonadales	C	COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, gamma subunit	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
CMS1_k127_3617438_1	1537715.JQFJ01000002_gene468	1.187e-178	564.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,2TR4R@28211|Alphaproteobacteria,2K1JI@204457|Sphingomonadales	204457|Sphingomonadales	C	COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
CMS1_k127_362021_1	1163407.UU7_00175	3.472e-99	331.0	COG0454@1|root,COG0456@2|Bacteria,1NHTY@1224|Proteobacteria,1T21B@1236|Gammaproteobacteria,1X69S@135614|Xanthomonadales	135614|Xanthomonadales	K	Domain of unknown function (DUF4915)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4915
CMS1_k127_362021_2	365044.Pnap_4542	1.276e-49	186.0	2C6BU@1|root,32S87@2|Bacteria,1NIFE@1224|Proteobacteria,2VRGB@28216|Betaproteobacteria,4AGT5@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_362021_0	231434.JQJH01000004_gene553	1.543e-106	355.0	COG0462@1|root,COG0462@2|Bacteria,1QHJ7@1224|Proteobacteria,2TVDW@28211|Alphaproteobacteria,3NATB@45404|Beijerinckiaceae	28211|Alphaproteobacteria	EF	Phosphoribosyl synthetase-associated domain	-	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	PAS_5,Pribosyl_synth,Pribosyltran_N
CMS1_k127_3640886_0	1174684.EBMC1_07290	2.051e-159	506.0	COG3386@1|root,COG3386@2|Bacteria,1MXVD@1224|Proteobacteria,2TVCW@28211|Alphaproteobacteria,2K1RT@204457|Sphingomonadales	204457|Sphingomonadales	G	SMP-30/Gluconolaconase/LRE-like region	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
CMS1_k127_3640886_2	1112216.JH594425_gene3179	9.412e-77	263.0	COG1814@1|root,COG1814@2|Bacteria,1MUZE@1224|Proteobacteria,2TT6M@28211|Alphaproteobacteria,2K1CI@204457|Sphingomonadales	204457|Sphingomonadales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
CMS1_k127_3640886_1	1545915.JROG01000003_gene1144	3.859e-94	318.0	COG1011@1|root,COG1011@2|Bacteria,1Q69X@1224|Proteobacteria,2TTTP@28211|Alphaproteobacteria,2K328@204457|Sphingomonadales	204457|Sphingomonadales	S	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
CMS1_k127_3640886_3	1192759.AKIB01000116_gene3658	1.049e-46	175.0	COG3031@1|root,COG3031@2|Bacteria,1RFDB@1224|Proteobacteria,2U64N@28211|Alphaproteobacteria,2K0SG@204457|Sphingomonadales	204457|Sphingomonadales	U	Type II secretory pathway component PulC	-	-	-	ko:K02452	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	PDZ_2,T2SSC
CMS1_k127_3654088_7	1248760.ANFZ01000004_gene2027	1.626e-56	198.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,2TRPH@28211|Alphaproteobacteria,2K1H1@204457|Sphingomonadales	204457|Sphingomonadales	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
CMS1_k127_3654088_10	1479239.JQMU01000001_gene1575	5.611e-42	158.0	COG3631@1|root,COG3631@2|Bacteria,1RH7J@1224|Proteobacteria,2UB56@28211|Alphaproteobacteria,2K5TZ@204457|Sphingomonadales	204457|Sphingomonadales	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
CMS1_k127_3654088_9	383381.EH30_15630	4.846e-42	160.0	COG1359@1|root,COG1359@2|Bacteria,1N7AV@1224|Proteobacteria,2UIVG@28211|Alphaproteobacteria,2K7DX@204457|Sphingomonadales	204457|Sphingomonadales	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
CMS1_k127_3654088_1	1248760.ANFZ01000002_gene3009	3.103e-155	500.0	COG2124@1|root,COG2124@2|Bacteria,1MY5H@1224|Proteobacteria,2TTRR@28211|Alphaproteobacteria,2K2HH@204457|Sphingomonadales	204457|Sphingomonadales	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
CMS1_k127_3654088_2	1545915.JROG01000009_gene2651	8.65e-102	337.0	COG1028@1|root,COG1028@2|Bacteria,1MUFX@1224|Proteobacteria,2VFFP@28211|Alphaproteobacteria,2KDWM@204457|Sphingomonadales	204457|Sphingomonadales	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS1_k127_3654088_8	1545915.JROG01000003_gene690	2.542e-53	197.0	2AKPD@1|root,31BG1@2|Bacteria,1N1HV@1224|Proteobacteria,2UEQ0@28211|Alphaproteobacteria,2K577@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3654088_6	685035.ADAE01000018_gene393	4.505e-60	210.0	COG5470@1|root,COG5470@2|Bacteria,1MWI7@1224|Proteobacteria,2U0S6@28211|Alphaproteobacteria,2K499@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF1330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1330
CMS1_k127_3654088_5	1248760.ANFZ01000009_gene892	2.018e-78	265.0	COG1670@1|root,COG1670@2|Bacteria,1RD77@1224|Proteobacteria,2U851@28211|Alphaproteobacteria,2K3YG@204457|Sphingomonadales	204457|Sphingomonadales	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
CMS1_k127_3654088_11	1331060.RLDS_14400	2.892e-15	79.0	2EIB4@1|root,33C2I@2|Bacteria,1NCTY@1224|Proteobacteria,2UHUB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3654088_4	1123270.ATUR01000004_gene1655	5.77e-79	273.0	COG2962@1|root,COG2962@2|Bacteria,1MX5G@1224|Proteobacteria,2TV8D@28211|Alphaproteobacteria,2K1SV@204457|Sphingomonadales	204457|Sphingomonadales	S	RarD protein	-	-	-	ko:K05786	-	-	-	-	ko00000,ko02000	2.A.7.7	-	-	EamA
CMS1_k127_3654088_0	1502850.FG91_02901	9.74e-163	519.0	COG0418@1|root,COG0418@2|Bacteria,1MUYP@1224|Proteobacteria,2TT2U@28211|Alphaproteobacteria,2K057@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
CMS1_k127_3654088_3	1346791.M529_06870	4.467e-96	322.0	COG0354@1|root,COG0354@2|Bacteria,1N852@1224|Proteobacteria,2TR8J@28211|Alphaproteobacteria,2K18B@204457|Sphingomonadales	204457|Sphingomonadales	S	Aminomethyltransferase	-	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T
CMS1_k127_3654088_12	1044.EH31_11825	7.408e-13	75.0	COG5373@1|root,COG5373@2|Bacteria,1N7JV@1224|Proteobacteria,2TR7A@28211|Alphaproteobacteria,2K53N@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF4167)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4167
CMS1_k127_3672581_9	1509405.GV67_20950	6.903e-57	215.0	COG2199@1|root,COG3706@2|Bacteria,1PG3X@1224|Proteobacteria,2V7IG@28211|Alphaproteobacteria,4B70F@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	7TM diverse intracellular signalling	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,GGDEF
CMS1_k127_3672581_7	314225.ELI_01235	1.569e-74	253.0	COG0346@1|root,COG0346@2|Bacteria,1RCYX@1224|Proteobacteria,2U7A8@28211|Alphaproteobacteria,2K4E9@204457|Sphingomonadales	204457|Sphingomonadales	E	COG0346 Lactoylglutathione lyase and related lyases	gloA	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
CMS1_k127_3672581_2	1248760.ANFZ01000014_gene2126	7.233e-107	351.0	COG2859@1|root,COG2859@2|Bacteria,1QU0K@1224|Proteobacteria,2U5D2@28211|Alphaproteobacteria,2K0TS@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF541)	-	-	-	ko:K09797	-	-	-	-	ko00000	-	-	-	SIMPL
CMS1_k127_3672581_8	1545915.JROG01000003_gene1678	3.229e-66	235.0	COG3063@1|root,COG3063@2|Bacteria,1QURU@1224|Proteobacteria,2UAST@28211|Alphaproteobacteria,2KEVF@204457|Sphingomonadales	204457|Sphingomonadales	NU	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16
CMS1_k127_3672581_3	1123269.NX02_24385	1.194e-95	318.0	COG1073@1|root,COG1073@2|Bacteria,1MX88@1224|Proteobacteria,2TSRE@28211|Alphaproteobacteria,2K1F6@204457|Sphingomonadales	204457|Sphingomonadales	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
CMS1_k127_3672581_11	1549858.MC45_10955	1.981e-08	60.0	COG0501@1|root,COG0501@2|Bacteria,1NK9F@1224|Proteobacteria,2TREZ@28211|Alphaproteobacteria,2K33U@204457|Sphingomonadales	204457|Sphingomonadales	O	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
CMS1_k127_3672581_0	1545915.JROG01000008_gene3401	0.0	1127.0	COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,2TQWI@28211|Alphaproteobacteria,2K14B@204457|Sphingomonadales	204457|Sphingomonadales	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
CMS1_k127_3672581_6	1144305.PMI02_03915	6.633e-81	273.0	COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,2U58Z@28211|Alphaproteobacteria,2K0EN@204457|Sphingomonadales	204457|Sphingomonadales	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
CMS1_k127_3672581_5	1248760.ANFZ01000009_gene1504	3.813e-82	280.0	COG0225@1|root,COG0225@2|Bacteria,1NC84@1224|Proteobacteria,2TTDD@28211|Alphaproteobacteria,2K3XP@204457|Sphingomonadales	204457|Sphingomonadales	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA_1	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
CMS1_k127_3672581_1	1335760.ASTG01000029_gene2378	7.176e-208	651.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2TRPK@28211|Alphaproteobacteria,2K0HJ@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate	aspB	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS1_k127_3672581_10	745310.G432_07710	9.344e-41	156.0	COG2824@1|root,COG2824@2|Bacteria,1RGUU@1224|Proteobacteria,2UFDJ@28211|Alphaproteobacteria,2K59J@204457|Sphingomonadales	204457|Sphingomonadales	P	PhnA protein	-	-	-	ko:K06193	ko01120,map01120	-	-	-	ko00000	-	-	-	PhnA
CMS1_k127_3672581_4	1174684.EBMC1_08446	1.907e-88	293.0	COG2873@1|root,COG2873@2|Bacteria,1NQME@1224|Proteobacteria,2TQW9@28211|Alphaproteobacteria,2K1N7@204457|Sphingomonadales	204457|Sphingomonadales	E	O-acetylhomoserine	metY	-	2.5.1.47,2.5.1.49	ko:K01738,ko:K01740	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R01287,R03601,R04859	RC00020,RC02814,RC02821,RC02848	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
CMS1_k127_3681693_4	1248760.ANFZ01000009_gene1303	9.017e-64	220.0	COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,2U5CS@28211|Alphaproteobacteria,2K3WY@204457|Sphingomonadales	204457|Sphingomonadales	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
CMS1_k127_3681693_5	13689.BV96_01372	4.88e-44	164.0	COG2927@1|root,COG2927@2|Bacteria,1RGVC@1224|Proteobacteria,2U94V@28211|Alphaproteobacteria,2K5Y0@204457|Sphingomonadales	204457|Sphingomonadales	L	DNA polymerase III	holC	-	2.7.7.7	ko:K02339	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_chi
CMS1_k127_3681693_1	1545915.JROG01000003_gene1107	5.783e-203	642.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,2TQU9@28211|Alphaproteobacteria,2K04B@204457|Sphingomonadales	204457|Sphingomonadales	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
CMS1_k127_3681693_0	1114964.L485_15915	1.285e-295	928.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,2TR3B@28211|Alphaproteobacteria,2K1GQ@204457|Sphingomonadales	204457|Sphingomonadales	M	Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA,OstA_C
CMS1_k127_3681693_2	1248760.ANFZ01000009_gene1308	2.825e-179	574.0	COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,2TSJ3@28211|Alphaproteobacteria,2K0UR@204457|Sphingomonadales	204457|Sphingomonadales	O	peptidylprolyl isomerase	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,SurA_N,SurA_N_3
CMS1_k127_3681693_3	1123270.ATUR01000005_gene459	4.103e-70	243.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,2TSKF@28211|Alphaproteobacteria,2K0HZ@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)	pdxA	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
CMS1_k127_3693686_0	1545915.JROG01000001_gene123	3.435e-178	561.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,2TRBW@28211|Alphaproteobacteria,2K0I2@204457|Sphingomonadales	204457|Sphingomonadales	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
CMS1_k127_3693686_2	1174684.EBMC1_09334	1.115e-22	113.0	2C3YK@1|root,2ZHJ2@2|Bacteria,1RKGM@1224|Proteobacteria,2UBK5@28211|Alphaproteobacteria,2K5GJ@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3693686_1	702113.PP1Y_AT23973	7.939e-28	117.0	COG0745@1|root,COG0745@2|Bacteria,1NH3M@1224|Proteobacteria,2UKPD@28211|Alphaproteobacteria,2K815@204457|Sphingomonadales	204457|Sphingomonadales	KT	RESPONSE REGULATOR receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS1_k127_3734254_7	1479239.JQMU01000001_gene1553	2.661e-57	205.0	COG0346@1|root,COG0346@2|Bacteria,1RK3P@1224|Proteobacteria,2UANZ@28211|Alphaproteobacteria,2K5JM@204457|Sphingomonadales	204457|Sphingomonadales	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS1_k127_3734254_2	1449076.JOOE01000001_gene2245	5.476e-124	414.0	COG3104@1|root,COG3104@2|Bacteria,1MW6W@1224|Proteobacteria,2U15C@28211|Alphaproteobacteria,2K2WX@204457|Sphingomonadales	204457|Sphingomonadales	E	amino acid peptide transporter	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
CMS1_k127_3734254_12	366602.Caul_3172	2.101e-17	88.0	COG3631@1|root,COG3631@2|Bacteria,1N487@1224|Proteobacteria,2UDWM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
CMS1_k127_3734254_9	1030157.AFMP01000044_gene1847	7.935e-35	138.0	2CVK5@1|root,32SXS@2|Bacteria,1N0ZG@1224|Proteobacteria,2UCR3@28211|Alphaproteobacteria,2K6N7@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3734254_0	1280947.HY30_11650	6.634e-219	699.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,43XNB@69657|Hyphomonadaceae	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2,TPR_16,TPR_8,Trans_reg_C
CMS1_k127_3734254_13	272943.RSP_1299	9.196e-14	85.0	COG0457@1|root,COG3629@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,1QYCE@1224|Proteobacteria,2TXNN@28211|Alphaproteobacteria,1FCZP@1060|Rhodobacter	28211|Alphaproteobacteria	K	intracellular signal transduction	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3734254_11	1379701.JPJC01000075_gene2569	3.344e-22	102.0	COG0745@1|root,COG0745@2|Bacteria,1N2D5@1224|Proteobacteria,2UUU2@28211|Alphaproteobacteria,2K55K@204457|Sphingomonadales	204457|Sphingomonadales	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS1_k127_3734254_6	1121949.AQXT01000002_gene565	3.265e-71	259.0	COG3920@1|root,COG3920@2|Bacteria,1MVPJ@1224|Proteobacteria,2TSSQ@28211|Alphaproteobacteria,43ZGW@69657|Hyphomonadaceae	28211|Alphaproteobacteria	T	Histidine kinase-like ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HATPase_c_2,HisKA_2,PAS,PAS_3,PAS_4,PAS_9
CMS1_k127_3734254_8	596152.DesU5LDRAFT_3326	3.148e-43	176.0	COG2203@1|root,COG4251@1|root,COG2203@2|Bacteria,COG4251@2|Bacteria,1RGKE@1224|Proteobacteria,43C1G@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4
CMS1_k127_3734254_10	1537715.JQFJ01000002_gene797	1.113e-33	138.0	COG5126@1|root,COG5126@2|Bacteria,1N0UM@1224|Proteobacteria,2UCE3@28211|Alphaproteobacteria,2KEC5@204457|Sphingomonadales	204457|Sphingomonadales	DTZ	EF-hand, calcium binding motif	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_5
CMS1_k127_3734254_3	1219049.SP5_007_00560	1.198e-101	335.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,2TTKG@28211|Alphaproteobacteria,2K0YQ@204457|Sphingomonadales	204457|Sphingomonadales	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_3734254_4	1248760.ANFZ01000006_gene2456	4.006e-99	347.0	COG0642@1|root,COG2205@2|Bacteria,1MUAK@1224|Proteobacteria,2TSUC@28211|Alphaproteobacteria,2JZUS@204457|Sphingomonadales	204457|Sphingomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
CMS1_k127_3734254_1	1123270.ATUR01000006_gene106	7.25e-184	588.0	COG2234@1|root,COG2234@2|Bacteria,1NE83@1224|Proteobacteria,2TSF8@28211|Alphaproteobacteria,2K0KQ@204457|Sphingomonadales	204457|Sphingomonadales	S	Peptidase, M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
CMS1_k127_3734254_5	745310.G432_01110	7.179e-94	311.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2TS7G@28211|Alphaproteobacteria,2K0YK@204457|Sphingomonadales	204457|Sphingomonadales	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
CMS1_k127_3762473_6	383381.EH30_14310	2.44e-60	224.0	COG1287@1|root,COG1287@2|Bacteria,1RCIB@1224|Proteobacteria,2TV2J@28211|Alphaproteobacteria,2KDNP@204457|Sphingomonadales	204457|Sphingomonadales	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3762473_8	314225.ELI_09040	1.114e-56	203.0	COG0346@1|root,COG0346@2|Bacteria,1N08M@1224|Proteobacteria,2UCUW@28211|Alphaproteobacteria,2K581@204457|Sphingomonadales	204457|Sphingomonadales	E	COG0346 Lactoylglutathione lyase and related lyases	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS1_k127_3762473_7	383381.EH30_14305	5.861e-57	210.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,2U70T@28211|Alphaproteobacteria,2K4P6@204457|Sphingomonadales	204457|Sphingomonadales	O	conserved domain frequently associated with peptide methionine sulfoxide reductase	-	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
CMS1_k127_3762473_1	1248760.ANFZ01000002_gene3045	4.432e-189	599.0	COG2124@1|root,COG2124@2|Bacteria,1MV8Q@1224|Proteobacteria,2TRWW@28211|Alphaproteobacteria,2K1ZZ@204457|Sphingomonadales	204457|Sphingomonadales	Q	cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
CMS1_k127_3762473_4	1248760.ANFZ01000011_gene222	1.367e-132	443.0	COG1668@1|root,COG1668@2|Bacteria,1MWAS@1224|Proteobacteria,2TU2K@28211|Alphaproteobacteria,2K1E9@204457|Sphingomonadales	204457|Sphingomonadales	CP	ABC-type Na efflux pump, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
CMS1_k127_3762473_3	1545915.JROG01000008_gene3418	2.715e-154	492.0	COG4152@1|root,COG4152@2|Bacteria,1QUPV@1224|Proteobacteria,2TW40@28211|Alphaproteobacteria,2JZWA@204457|Sphingomonadales	204457|Sphingomonadales	S	ABC transporter, ATP-binding protein	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_3762473_2	1550073.JROH01000036_gene2682	1.1e-159	509.0	COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,2TR5E@28211|Alphaproteobacteria,2K0HW@204457|Sphingomonadales	204457|Sphingomonadales	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
CMS1_k127_3762473_10	1248760.ANFZ01000006_gene2398	7.2e-26	115.0	2EHHR@1|root,33B9P@2|Bacteria,1NGHW@1224|Proteobacteria,2UJVS@28211|Alphaproteobacteria,2K6SJ@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3762473_9	1123270.ATUR01000004_gene1795	6.119e-53	194.0	COG2981@1|root,COG2981@2|Bacteria,1MWAA@1224|Proteobacteria,2TT6E@28211|Alphaproteobacteria,2K1BQ@204457|Sphingomonadales	204457|Sphingomonadales	E	protein involved in cysteine biosynthesis	-	-	-	ko:K06203	-	-	-	-	ko00000	-	-	-	EI24
CMS1_k127_3762473_5	1545915.JROG01000004_gene2391	5.532e-131	426.0	COG0524@1|root,COG0524@2|Bacteria,1MUUC@1224|Proteobacteria,2TS9D@28211|Alphaproteobacteria,2K0DX@204457|Sphingomonadales	204457|Sphingomonadales	G	Carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
CMS1_k127_3762473_0	1545915.JROG01000007_gene3261	1.829e-222	698.0	COG2244@1|root,COG2244@2|Bacteria,1PDRG@1224|Proteobacteria,2TVKM@28211|Alphaproteobacteria,2K0P5@204457|Sphingomonadales	204457|Sphingomonadales	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3
CMS1_k127_3766942_2	627192.SLG_11790	5.79e-214	670.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,2TRHK@28211|Alphaproteobacteria,2K00E@204457|Sphingomonadales	204457|Sphingomonadales	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2
CMS1_k127_3766942_4	383381.EH30_12345	1.13e-125	408.0	COG3000@1|root,COG3000@2|Bacteria,1R48K@1224|Proteobacteria,2U4WF@28211|Alphaproteobacteria,2K7FG@204457|Sphingomonadales	204457|Sphingomonadales	I	Fatty acid hydroxylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
CMS1_k127_3766942_12	1174684.EBMC1_07455	2.728e-38	152.0	COG0664@1|root,COG0664@2|Bacteria,1NAU9@1224|Proteobacteria,2UHMJ@28211|Alphaproteobacteria,2K743@204457|Sphingomonadales	204457|Sphingomonadales	K	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
CMS1_k127_3766942_9	1123270.ATUR01000002_gene2386	5.24e-67	239.0	2BXI0@1|root,2Z9A2@2|Bacteria,1MZF7@1224|Proteobacteria,2UCIX@28211|Alphaproteobacteria,2K3UM@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF2459)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2459
CMS1_k127_3766942_3	1219049.SP5_017_00360	5.997e-141	452.0	COG3186@1|root,COG3186@2|Bacteria,1MU29@1224|Proteobacteria,2TU1E@28211|Alphaproteobacteria,2K01F@204457|Sphingomonadales	204457|Sphingomonadales	E	Phenylalanine-4-hydroxylase	phhA	-	1.14.16.1	ko:K00500	ko00360,ko00400,ko00790,ko01100,ko01230,map00360,map00400,map00790,map01100,map01230	-	R01795,R07211	RC00490	ko00000,ko00001,ko01000	-	-	-	Biopterin_H
CMS1_k127_3766942_6	317655.Sala_0554	1.962e-96	325.0	COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,2TTP3@28211|Alphaproteobacteria,2K0Q7@204457|Sphingomonadales	204457|Sphingomonadales	J	ribosomal protein L11	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
CMS1_k127_3766942_0	745310.G432_11370	4.502e-286	889.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2TQRZ@28211|Alphaproteobacteria,2K1B4@204457|Sphingomonadales	204457|Sphingomonadales	S	of ABC transporters with duplicated ATPase	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
CMS1_k127_3766942_1	1120705.FG95_00438	5.721e-263	820.0	COG2234@1|root,COG2234@2|Bacteria,1MV86@1224|Proteobacteria,2TVJ5@28211|Alphaproteobacteria,2K04D@204457|Sphingomonadales	204457|Sphingomonadales	S	Peptidase, M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
CMS1_k127_3766942_7	1088721.NSU_4744	6.393e-94	323.0	COG3174@1|root,COG3174@2|Bacteria,1NDBI@1224|Proteobacteria,2U0C9@28211|Alphaproteobacteria,2K374@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF4010)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010,MgtC
CMS1_k127_3766942_8	1470591.BW41_02607	4.199e-78	278.0	COG4262@1|root,COG4262@2|Bacteria,1P1G3@1224|Proteobacteria,2TQSR@28211|Alphaproteobacteria,2K07Q@204457|Sphingomonadales	204457|Sphingomonadales	S	Spermidine synthase	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
CMS1_k127_3766942_5	1123270.ATUR01000002_gene2389	1.455e-99	331.0	COG1028@1|root,COG1028@2|Bacteria,1R8HN@1224|Proteobacteria,2U0TG@28211|Alphaproteobacteria,2K2FB@204457|Sphingomonadales	204457|Sphingomonadales	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
CMS1_k127_3766942_11	1144305.PMI02_04015	2.215e-49	180.0	COG2009@1|root,COG2009@2|Bacteria,1N02N@1224|Proteobacteria,2UC47@28211|Alphaproteobacteria,2K6ED@204457|Sphingomonadales	204457|Sphingomonadales	C	succinate dehydrogenase	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
CMS1_k127_3766942_10	1331060.RLDS_13570	8.21e-53	188.0	COG2142@1|root,COG2142@2|Bacteria,1MZND@1224|Proteobacteria,2UC3G@28211|Alphaproteobacteria,2K550@204457|Sphingomonadales	204457|Sphingomonadales	C	succinate dehydrogenase	sdhD	-	-	ko:K00242	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
CMS1_k127_3766942_13	279238.Saro_1746	2.902e-05	50.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,2TQJA@28211|Alphaproteobacteria,2K1NE@204457|Sphingomonadales	204457|Sphingomonadales	C	Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
CMS1_k127_3824759_5	1123270.ATUR01000003_gene1069	7.779e-117	380.0	COG0334@1|root,COG0334@2|Bacteria,1MUXS@1224|Proteobacteria,2VGKD@28211|Alphaproteobacteria,2K0AY@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.9	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	-	R01088,R01434,R02196	RC00006,RC00036	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
CMS1_k127_3824759_9	1522072.IL54_4459	2.467e-83	288.0	COG3156@1|root,COG3156@2|Bacteria,1RAQM@1224|Proteobacteria,2U6QZ@28211|Alphaproteobacteria,2K0PH@204457|Sphingomonadales	204457|Sphingomonadales	U	Type II secretion system protein K	-	-	-	ko:K02460	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSK
CMS1_k127_3824759_16	745310.G432_00340	2.711e-39	153.0	COG4795@1|root,COG4795@2|Bacteria,1RJAE@1224|Proteobacteria,2UAXM@28211|Alphaproteobacteria,2K56Q@204457|Sphingomonadales	204457|Sphingomonadales	U	General secretion pathway protein	gspJ	-	-	ko:K02459	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSJ
CMS1_k127_3824759_7	685035.ADAE01000020_gene1512	5.803e-88	295.0	COG3751@1|root,COG3751@2|Bacteria,1R9PW@1224|Proteobacteria,2TT9Q@28211|Alphaproteobacteria,2K2TP@204457|Sphingomonadales	204457|Sphingomonadales	O	oxygenase	-	-	1.14.11.2	ko:K00472	ko00330,ko01100,map00330,map01100	-	R01252	RC00478	ko00000,ko00001,ko01000	-	-	-	2OG-FeII_Oxy_3
CMS1_k127_3824759_4	551275.KB899546_gene1975	3.509e-122	404.0	COG1914@1|root,COG1914@2|Bacteria,1MW6X@1224|Proteobacteria,2TUTC@28211|Alphaproteobacteria,43XA8@69657|Hyphomonadaceae	28211|Alphaproteobacteria	P	COG1914 Mn2 and Fe2 transporters of the NRAMP family	mntH	GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281	-	ko:K03322	-	-	-	-	ko00000,ko02000	2.A.55.2.6,2.A.55.3	-	-	Nramp
CMS1_k127_3824759_13	1545915.JROG01000004_gene2370	4.899e-60	224.0	COG1540@1|root,COG1540@2|Bacteria,1MUYV@1224|Proteobacteria,2TQUC@28211|Alphaproteobacteria,2K4MU@204457|Sphingomonadales	204457|Sphingomonadales	S	LamB/YcsF family	-	-	-	-	-	-	-	-	-	-	-	-	LamB_YcsF
CMS1_k127_3824759_14	1123270.ATUR01000003_gene1072	1.747e-50	192.0	COG2049@1|root,COG2049@2|Bacteria,1MWRB@1224|Proteobacteria,2U0AE@28211|Alphaproteobacteria,2K5CP@204457|Sphingomonadales	204457|Sphingomonadales	E	Allophanate hydrolase subunit 1	-	-	-	-	-	-	-	-	-	-	-	-	CT_C_D
CMS1_k127_3824759_12	1545915.JROG01000004_gene2368	1.907e-72	261.0	COG1984@1|root,COG1984@2|Bacteria,1MU9H@1224|Proteobacteria,2TS7P@28211|Alphaproteobacteria,2K5TG@204457|Sphingomonadales	204457|Sphingomonadales	E	Allophanate hydrolase subunit 2	-	-	-	-	-	-	-	-	-	-	-	-	CT_A_B
CMS1_k127_3824759_17	1123270.ATUR01000003_gene1074	3.07e-39	150.0	COG0254@1|root,COG0254@2|Bacteria,1MZ69@1224|Proteobacteria,2UBSC@28211|Alphaproteobacteria,2K643@204457|Sphingomonadales	204457|Sphingomonadales	J	50S ribosomal protein L31	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
CMS1_k127_3824759_11	1123270.ATUR01000003_gene1075	5.912e-74	250.0	COG0764@1|root,COG0764@2|Bacteria,1RH2T@1224|Proteobacteria,2U7G4@28211|Alphaproteobacteria,2K4JA@204457|Sphingomonadales	204457|Sphingomonadales	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
CMS1_k127_3824759_18	1449076.JOOE01000001_gene1719	3.666e-39	154.0	COG2825@1|root,COG2825@2|Bacteria,1NFPH@1224|Proteobacteria,2U9NJ@28211|Alphaproteobacteria,2KDJR@204457|Sphingomonadales	204457|Sphingomonadales	M	Outer membrane protein (OmpH-like)	-	-	-	-	-	-	-	-	-	-	-	-	OmpH
CMS1_k127_3824759_0	1248760.ANFZ01000009_gene1531	0.0	1272.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,2TR7W@28211|Alphaproteobacteria,2K0GI@204457|Sphingomonadales	204457|Sphingomonadales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
CMS1_k127_3824759_1	1545915.JROG01000003_gene1294	1.496e-155	500.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,2TQXJ@28211|Alphaproteobacteria,2K0AZ@204457|Sphingomonadales	204457|Sphingomonadales	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
CMS1_k127_3824759_2	1248760.ANFZ01000009_gene1529	4.667e-155	500.0	COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,2TSD1@28211|Alphaproteobacteria,2K0YA@204457|Sphingomonadales	204457|Sphingomonadales	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
CMS1_k127_3824759_10	1545915.JROG01000003_gene1292	5.449e-82	284.0	COG0575@1|root,COG0575@2|Bacteria,1MWSV@1224|Proteobacteria,2U9ED@28211|Alphaproteobacteria,2K1ET@204457|Sphingomonadales	204457|Sphingomonadales	I	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
CMS1_k127_3824759_6	1248760.ANFZ01000009_gene1527	6.486e-98	328.0	COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,2TTVJ@28211|Alphaproteobacteria,2K0JM@204457|Sphingomonadales	204457|Sphingomonadales	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
CMS1_k127_3824759_8	1123270.ATUR01000003_gene1082	5.356e-84	281.0	COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,2U5B2@28211|Alphaproteobacteria,2K00Z@204457|Sphingomonadales	204457|Sphingomonadales	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
CMS1_k127_3824759_3	13690.CP98_01390	7.41e-124	400.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,2TQYN@28211|Alphaproteobacteria,2K1B1@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
CMS1_k127_3824759_15	1219035.NT2_01_03450	4.251e-43	158.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,2TQM0@28211|Alphaproteobacteria,2JZY1@204457|Sphingomonadales	204457|Sphingomonadales	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
CMS1_k127_3834759_4	383381.EH30_09750	3.003e-69	251.0	COG0644@1|root,COG0644@2|Bacteria,1MXQY@1224|Proteobacteria,2TVK0@28211|Alphaproteobacteria,2K22X@204457|Sphingomonadales	204457|Sphingomonadales	C	geranylgeranyl reductase	-	-	1.3.1.111,1.3.1.83	ko:K10960	ko00860,ko00900,ko01100,ko01110,map00860,map00900,map01100,map01110	-	R02063,R08754,R08755,R08756,R11226,R11518	RC00212,RC00522,RC01823	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3,Lycopene_cycl,NAD_binding_8,Pyr_redox_2
CMS1_k127_3834759_0	1545915.JROG01000009_gene2678	3.219e-144	475.0	COG2211@1|root,COG2211@2|Bacteria,1MWE4@1224|Proteobacteria,2TQY7@28211|Alphaproteobacteria,2K1IR@204457|Sphingomonadales	204457|Sphingomonadales	G	PUCC protein	-	-	-	ko:K08226	-	-	-	-	ko00000,ko02000	2.A.1.41	-	-	PUCC
CMS1_k127_3834759_2	1248760.ANFZ01000023_gene100	8.203e-125	406.0	COG0382@1|root,COG0382@2|Bacteria,1MVS1@1224|Proteobacteria,2TVKN@28211|Alphaproteobacteria,2K2ED@204457|Sphingomonadales	204457|Sphingomonadales	H	UbiA prenyltransferase family	-	-	2.5.1.133,2.5.1.62	ko:K04040	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06284,R09067,R11514,R11517	RC00020	ko00000,ko00001,ko01000,ko01006	-	-	-	UbiA
CMS1_k127_3834759_1	1248760.ANFZ01000023_gene102	7.725e-130	429.0	COG2204@1|root,COG2204@2|Bacteria,1P98K@1224|Proteobacteria,2TUM0@28211|Alphaproteobacteria,2K3AF@204457|Sphingomonadales	204457|Sphingomonadales	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS_4,PAS_8
CMS1_k127_3834759_6	237727.NAP1_09377	1.391e-65	235.0	COG5012@1|root,COG5012@2|Bacteria,1RJN6@1224|Proteobacteria,2U9SK@28211|Alphaproteobacteria,2K2S6@204457|Sphingomonadales	204457|Sphingomonadales	S	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding
CMS1_k127_3834759_5	383381.EH30_09775	1.321e-67	235.0	294R4@1|root,2ZS4D@2|Bacteria,1RDGM@1224|Proteobacteria,2U71V@28211|Alphaproteobacteria,2K4C2@204457|Sphingomonadales	204457|Sphingomonadales	S	2-vinyl bacteriochlorophyllide hydratase (BCHF)	-	-	4.2.1.165	ko:K11336	ko00860,ko01110,map00860,map01110	-	R09054,R09059	RC02412	ko00000,ko00001,ko01000	-	-	-	BCHF
CMS1_k127_3834759_3	237727.NAP1_09387	2.773e-105	349.0	COG2710@1|root,COG2710@2|Bacteria,1MVP0@1224|Proteobacteria,2TSK1@28211|Alphaproteobacteria,2K0EI@204457|Sphingomonadales	204457|Sphingomonadales	C	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex	bchN	-	1.3.7.7	ko:K04038	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06282	RC01008	ko00000,ko00001,ko01000	-	-	-	Oxidored_nitro
CMS1_k127_3854947_3	1537715.JQFJ01000002_gene520	1.041e-73	251.0	COG3588@1|root,COG3588@2|Bacteria,1MVFK@1224|Proteobacteria,2TU2S@28211|Alphaproteobacteria,2K14P@204457|Sphingomonadales	204457|Sphingomonadales	G	Catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate in glycolysis	fbaB	-	4.1.2.13	ko:K01623	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000,ko03036,ko04131,ko04147	-	-	-	Glycolytic
CMS1_k127_3854947_1	1248760.ANFZ01000009_gene985	3.619e-192	605.0	COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,2TSKQ@28211|Alphaproteobacteria,2K0JN@204457|Sphingomonadales	204457|Sphingomonadales	F	Belongs to the phosphoglycerate kinase family	pgk	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
CMS1_k127_3854947_2	685035.ADAE01000018_gene540	1.736e-186	587.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,2TR6E@28211|Alphaproteobacteria,2K0GC@204457|Sphingomonadales	204457|Sphingomonadales	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapA	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
CMS1_k127_3854947_0	1502850.FG91_00255	0.0	1023.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,2TQUX@28211|Alphaproteobacteria,2K0UZ@204457|Sphingomonadales	204457|Sphingomonadales	G	Belongs to the transketolase family	tktA	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
CMS1_k127_3854947_5	279238.Saro_1970	8.936e-18	87.0	COG3027@1|root,COG3027@2|Bacteria,1Q3M7@1224|Proteobacteria,2VACI@28211|Alphaproteobacteria,2K78U@204457|Sphingomonadales	204457|Sphingomonadales	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	-	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
CMS1_k127_3854947_4	1219045.BV98_001089	2.85e-41	160.0	COG0212@1|root,COG0212@2|Bacteria,1MZG0@1224|Proteobacteria,2UBY4@28211|Alphaproteobacteria,2K4QF@204457|Sphingomonadales	204457|Sphingomonadales	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	-	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
CMS1_k127_3854947_6	1470591.BW41_00370	2.147e-17	84.0	28WVU@1|root,2ZIV5@2|Bacteria,1NGX2@1224|Proteobacteria,2UJJ9@28211|Alphaproteobacteria,2K6RU@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF2842)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2842
CMS1_k127_3858578_2	741091.Rahaq_2251	5.593e-44	162.0	COG1215@1|root,COG1215@2|Bacteria,1MWH9@1224|Proteobacteria,1RPTN@1236|Gammaproteobacteria,3FF7M@34037|Rahnella	1236|Gammaproteobacteria	M	COG0463 Glycosyltransferases involved in cell wall biogenesis	wcaA	-	2.4.1.266	ko:K13693	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	-
CMS1_k127_3858578_3	314271.RB2654_06569	3.022e-43	168.0	COG3769@1|root,COG3769@2|Bacteria,1NFV5@1224|Proteobacteria,2U6BB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	hydrolase (HAD superfamily)	-	-	3.1.3.70	ko:K07026	ko00051,map00051	-	R05790	RC00017	ko00000,ko00001,ko01000	-	-	-	Hydrolase_3
CMS1_k127_3858578_0	553385.JEMF01000032_gene2575	2.086e-152	501.0	COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,1RMD2@1236|Gammaproteobacteria,1XH63@135619|Oceanospirillales	135619|Oceanospirillales	E	Belongs to the GMC oxidoreductase family	-	-	1.1.99.1	ko:K00108	ko00260,ko01100,map00260,map01100	M00555	R01025	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
CMS1_k127_3858578_4	1168059.KB899087_gene1061	7.165e-10	60.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,3F0VP@335928|Xanthobacteraceae	28211|Alphaproteobacteria	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
CMS1_k127_3858578_1	13689.BV96_01794	8.691e-81	276.0	COG2951@1|root,COG2951@2|Bacteria,1MUZ3@1224|Proteobacteria,2TRP0@28211|Alphaproteobacteria,2K0TV@204457|Sphingomonadales	204457|Sphingomonadales	M	Lytic murein transglycosylase	mltB	-	-	-	-	-	-	-	-	-	-	-	SLT_2
CMS1_k127_3929197_0	392499.Swit_4474	2.341e-200	627.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,2TQUE@28211|Alphaproteobacteria,2K0GV@204457|Sphingomonadales	204457|Sphingomonadales	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
CMS1_k127_3929197_1	392499.Swit_3015	6.801e-148	477.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,2TSD0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11,2.7.1.90	ko:K00850,ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R00764,R02073,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
CMS1_k127_3929197_2	1123270.ATUR01000002_gene2700	4.896e-97	322.0	COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,2TQXM@28211|Alphaproteobacteria,2K0WQ@204457|Sphingomonadales	204457|Sphingomonadales	L	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
CMS1_k127_3929197_3	1123270.ATUR01000002_gene2701	4.584e-65	240.0	COG2911@1|root,COG2911@2|Bacteria,1R4BU@1224|Proteobacteria,2TSKR@28211|Alphaproteobacteria,2K0MI@204457|Sphingomonadales	204457|Sphingomonadales	S	Dicarboxylate transport	-	-	-	-	-	-	-	-	-	-	-	-	DctA-YdbH
CMS1_k127_3932119_5	317655.Sala_2246	1.729e-39	150.0	COG3173@1|root,COG3173@2|Bacteria,1R7XK@1224|Proteobacteria,2TTWB@28211|Alphaproteobacteria,2K39Q@204457|Sphingomonadales	204457|Sphingomonadales	S	Ecdysteroid kinase	-	-	-	-	-	-	-	-	-	-	-	-	APH,EcKinase
CMS1_k127_3932119_0	1123269.NX02_16565	1.587e-176	568.0	COG1485@1|root,COG1485@2|Bacteria,1MUUW@1224|Proteobacteria,2TRG1@28211|Alphaproteobacteria,2K2A7@204457|Sphingomonadales	204457|Sphingomonadales	S	AFG1 family ATPase	-	-	-	ko:K06916	-	-	-	-	ko00000,ko03036	-	-	-	AFG1_ATPase
CMS1_k127_3932119_4	1379701.JPJC01000112_gene491	5.685e-40	154.0	COG2050@1|root,COG2050@2|Bacteria,1MZPH@1224|Proteobacteria,2UDIQ@28211|Alphaproteobacteria,2K62E@204457|Sphingomonadales	204457|Sphingomonadales	Q	protein, possibly involved in aromatic compounds catabolism	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
CMS1_k127_3932119_1	392499.Swit_1304	1.049e-151	482.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,2TQYF@28211|Alphaproteobacteria,2K0CN@204457|Sphingomonadales	204457|Sphingomonadales	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_17
CMS1_k127_3932119_3	1502850.FG91_03635	1.013e-79	275.0	COG0657@1|root,COG0657@2|Bacteria,1N2XW@1224|Proteobacteria,2U3QT@28211|Alphaproteobacteria,2K2SB@204457|Sphingomonadales	204457|Sphingomonadales	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,COesterase
CMS1_k127_3932119_2	1122137.AQXF01000001_gene2762	1.108e-144	462.0	COG0498@1|root,COG0498@2|Bacteria,1R7X1@1224|Proteobacteria,2TUR3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Threonine synthase	MA20_41710	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS1_k127_3938121_13	1254432.SCE1572_36840	1.506e-41	155.0	COG0508@1|root,COG0508@2|Bacteria,1MUGY@1224|Proteobacteria,42PEC@68525|delta/epsilon subdivisions,2X5JG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
CMS1_k127_3938121_14	1208323.B30_02770	9.442e-12	73.0	COG0236@1|root,COG0236@2|Bacteria,1NHIC@1224|Proteobacteria,2UFUJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
CMS1_k127_3938121_1	246200.SPO0466	8.393e-93	312.0	COG2116@1|root,COG2116@2|Bacteria,1MU0W@1224|Proteobacteria,2TTIW@28211|Alphaproteobacteria,4NCXE@97050|Ruegeria	28211|Alphaproteobacteria	P	Formate/nitrite transporter	-	-	-	ko:K21993	-	-	-	-	ko00000,ko02000	1.A.16.2	-	-	Form_Nir_trans
CMS1_k127_3938121_11	1248760.ANFZ01000009_gene1456	5.685e-48	179.0	COG0801@1|root,COG0801@2|Bacteria,1MZH8@1224|Proteobacteria,2U8D6@28211|Alphaproteobacteria,2K57H@204457|Sphingomonadales	204457|Sphingomonadales	H	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
CMS1_k127_3938121_10	1123270.ATUR01000002_gene2171	1.029e-48	190.0	COG2032@1|root,COG2032@2|Bacteria,1RGV4@1224|Proteobacteria,2UC22@28211|Alphaproteobacteria,2K541@204457|Sphingomonadales	204457|Sphingomonadales	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodC	-	1.15.1.1	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Cu
CMS1_k127_3938121_7	1123269.NX02_13160	7.845e-61	213.0	COG0394@1|root,COG0394@2|Bacteria,1RH90@1224|Proteobacteria,2U72X@28211|Alphaproteobacteria,2K5E1@204457|Sphingomonadales	204457|Sphingomonadales	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	ptpA	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
CMS1_k127_3938121_0	745310.G432_02565	7.503e-100	331.0	COG0670@1|root,COG0670@2|Bacteria,1MU69@1224|Proteobacteria,2TRSF@28211|Alphaproteobacteria,2K14K@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the BI1 family	-	-	-	ko:K06890	-	-	-	-	ko00000	-	-	-	Bax1-I
CMS1_k127_3938121_12	517722.AEUE01000004_gene807	5.318e-44	170.0	2FE0D@1|root,3460K@2|Bacteria,1N3CI@1224|Proteobacteria,2U96F@28211|Alphaproteobacteria,2K5QV@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
CMS1_k127_3938121_5	1090320.KB900605_gene714	2.802e-80	272.0	COG0625@1|root,COG0625@2|Bacteria,1RA05@1224|Proteobacteria,2TS58@28211|Alphaproteobacteria,2K1M0@204457|Sphingomonadales	204457|Sphingomonadales	O	Glutathione S-transferase	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N,GST_N_3
CMS1_k127_3938121_3	1380387.JADM01000012_gene1528	2.646e-84	288.0	COG0625@1|root,COG0625@2|Bacteria,1PENB@1224|Proteobacteria,1SBMB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	PFAM Glutathione S-transferase, N-terminal domain	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N_3
CMS1_k127_3938121_2	1122194.AUHU01000006_gene415	3.796e-85	289.0	COG3324@1|root,COG3324@2|Bacteria,1R81W@1224|Proteobacteria,1RYXR@1236|Gammaproteobacteria,46C4C@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
CMS1_k127_3938121_8	1248916.ANFY01000003_gene722	1.353e-54	194.0	COG5507@1|root,COG5507@2|Bacteria,1RHC1@1224|Proteobacteria,2UC7A@28211|Alphaproteobacteria,2K5Z8@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF1428)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1428
CMS1_k127_3938121_6	1120705.FG95_01291	1.434e-73	249.0	COG3795@1|root,COG3795@2|Bacteria,1RCZT@1224|Proteobacteria,2U735@28211|Alphaproteobacteria,2K4WC@204457|Sphingomonadales	204457|Sphingomonadales	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
CMS1_k127_3938121_4	716928.AJQT01000105_gene2501	3.618e-82	275.0	COG3865@1|root,COG3865@2|Bacteria,1N7IY@1224|Proteobacteria,2U993@28211|Alphaproteobacteria,4B973@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	protein conserved in bacteria	-	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	3-dmu-9_3-mt
CMS1_k127_3938121_9	1122603.ATVI01000005_gene3775	6.493e-50	179.0	COG3607@1|root,COG3607@2|Bacteria,1RH1T@1224|Proteobacteria,1S6FE@1236|Gammaproteobacteria,1X739@135614|Xanthomonadales	135614|Xanthomonadales	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K07032	-	-	-	-	ko00000	-	-	-	-
CMS1_k127_3981345_4	1120705.FG95_02398	4.713e-42	156.0	COG2983@1|root,COG2983@2|Bacteria,1RHMX@1224|Proteobacteria,2U99S@28211|Alphaproteobacteria,2K4JE@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the UPF0260 family	-	-	-	ko:K09160	-	-	-	-	ko00000	-	-	-	CxxCxxCC
CMS1_k127_3981345_0	1030157.AFMP01000004_gene2030	5.445e-72	248.0	COG1999@1|root,COG1999@2|Bacteria,1RHJ8@1224|Proteobacteria,2U0Q3@28211|Alphaproteobacteria,2K4RS@204457|Sphingomonadales	204457|Sphingomonadales	S	protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
CMS1_k127_3981345_1	1545915.JROG01000004_gene1745	6.851e-64	226.0	COG0666@1|root,COG0666@2|Bacteria,1RFFD@1224|Proteobacteria,2U8T6@28211|Alphaproteobacteria,2K4S6@204457|Sphingomonadales	204457|Sphingomonadales	S	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank,Ank_2,Ank_4,Ank_5
CMS1_k127_3981345_3	1219035.NT2_04_02860	2.182e-50	184.0	COG5321@1|root,COG5321@2|Bacteria,1RDXW@1224|Proteobacteria,2U73Y@28211|Alphaproteobacteria,2K4NV@204457|Sphingomonadales	204457|Sphingomonadales	S	DNA repair protein MmcB-like	-	-	-	-	-	-	-	-	-	-	-	-	MmcB-like
CMS1_k127_3981345_2	1123270.ATUR01000004_gene1483	7.073e-57	206.0	COG3773@1|root,COG3773@2|Bacteria,1RDSV@1224|Proteobacteria,2U8XY@28211|Alphaproteobacteria,2K4PG@204457|Sphingomonadales	204457|Sphingomonadales	M	COG3773 Cell wall hydrolyses involved in spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_2
CMS1_k127_3981345_5	1207055.C100_12990	7.28e-24	104.0	COG5447@1|root,COG5447@2|Bacteria,1N1KU@1224|Proteobacteria,2UFES@28211|Alphaproteobacteria,2K70S@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF1491)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1491
CMS1_k127_4006462_7	314266.SKA58_04190	1.34e-13	72.0	COG4625@1|root,COG5640@1|root,COG4625@2|Bacteria,COG5640@2|Bacteria,1NS3H@1224|Proteobacteria,2U1SB@28211|Alphaproteobacteria,2K2MI@204457|Sphingomonadales	204457|Sphingomonadales	E	Trypsin-like serine protease	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,PATR,Peptidase_S8,Trypsin
CMS1_k127_4006462_4	1545915.JROG01000009_gene2863	8.513e-77	261.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2UF6W@28211|Alphaproteobacteria,2JZZ2@204457|Sphingomonadales	204457|Sphingomonadales	K	Cold shock	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
CMS1_k127_4006462_8	1123270.ATUR01000004_gene1521	1.622e-05	51.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2UF6W@28211|Alphaproteobacteria,2JZZ2@204457|Sphingomonadales	204457|Sphingomonadales	K	Cold shock	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
CMS1_k127_4006462_6	1088721.NSU_1452	2.02e-30	124.0	COG3671@1|root,COG3671@2|Bacteria,1MZMW@1224|Proteobacteria,2UG15@28211|Alphaproteobacteria,2K63N@204457|Sphingomonadales	204457|Sphingomonadales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4006462_2	1219045.BV98_001861	2.195e-106	347.0	COG0349@1|root,COG0349@2|Bacteria,1MWFD@1224|Proteobacteria,2TQXS@28211|Alphaproteobacteria,2K0FG@204457|Sphingomonadales	204457|Sphingomonadales	L	3'-5' exonuclease	-	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1
CMS1_k127_4006462_3	1346791.M529_19180	2.726e-77	264.0	COG5375@1|root,COG5375@2|Bacteria,1NMV8@1224|Proteobacteria,2VCS4@28211|Alphaproteobacteria,2K34V@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein conserved in bacteria	-	-	-	ko:K11719	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptC
CMS1_k127_4006462_5	452662.SJA_C1-31280	3.236e-65	227.0	COG1934@1|root,COG1934@2|Bacteria,1MXGA@1224|Proteobacteria,2U6DD@28211|Alphaproteobacteria,2K3YP@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA
CMS1_k127_4006462_1	1123270.ATUR01000004_gene1525	6.875e-131	421.0	COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,2TR7F@28211|Alphaproteobacteria,2K0YX@204457|Sphingomonadales	204457|Sphingomonadales	S	ABC-type (Unclassified) transport system, ATPase component	-	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
CMS1_k127_4006462_0	1081640.AGFU01000006_gene1233	1.335e-204	648.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,2TS41@28211|Alphaproteobacteria,2K182@204457|Sphingomonadales	204457|Sphingomonadales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
CMS1_k127_4017880_4	1380350.JIAP01000007_gene2453	8.327e-25	107.0	COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,2TQKQ@28211|Alphaproteobacteria,43N03@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Belongs to the GMC oxidoreductase family	MA20_19170	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
CMS1_k127_4017880_2	1449076.JOOE01000003_gene3566	1.237e-141	455.0	COG3000@1|root,COG3000@2|Bacteria,1NR7X@1224|Proteobacteria,2TT68@28211|Alphaproteobacteria,2K2GA@204457|Sphingomonadales	204457|Sphingomonadales	I	sterol desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
CMS1_k127_4017880_3	1248760.ANFZ01000011_gene300	2.442e-55	200.0	COG3453@1|root,COG3453@2|Bacteria,1N9AF@1224|Proteobacteria,2UD2M@28211|Alphaproteobacteria,2K56H@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF442
CMS1_k127_4017880_0	1112212.JH584235_gene2576	3.007e-270	846.0	COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,2TS8B@28211|Alphaproteobacteria,2K0QS@204457|Sphingomonadales	204457|Sphingomonadales	L	DNA helicase	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
CMS1_k127_4017880_1	1123270.ATUR01000007_gene1330	3.075e-256	800.0	COG5265@1|root,COG5265@2|Bacteria,1NSKS@1224|Proteobacteria,2UQAG@28211|Alphaproteobacteria,2K16I@204457|Sphingomonadales	204457|Sphingomonadales	V	ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS1_k127_40236_3	1545915.JROG01000004_gene1940	3.477e-141	454.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,2U059@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Cysteine-rich domain	-	-	1.1.5.3	ko:K00113	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	CCG
CMS1_k127_40236_5	1545915.JROG01000004_gene1941	1.619e-78	266.0	COG0247@1|root,COG0247@2|Bacteria,1RF02@1224|Proteobacteria,2U69V@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Protein of unknown function (DUF3501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3501
CMS1_k127_40236_2	1030157.AFMP01000062_gene3546	4.323e-193	612.0	COG1396@1|root,COG3800@1|root,COG1396@2|Bacteria,COG3800@2|Bacteria,1MU50@1224|Proteobacteria,2TRKE@28211|Alphaproteobacteria,2K126@204457|Sphingomonadales	204457|Sphingomonadales	K	Transcriptional regulator	-	-	-	ko:K07110	-	-	-	-	ko00000,ko03000	-	-	-	DUF2083,HTH_19,HTH_3,HTH_31,Peptidase_M78
CMS1_k127_40236_1	1207055.C100_07470	1.612e-209	659.0	COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,2TRZA@28211|Alphaproteobacteria,2K0H7@204457|Sphingomonadales	204457|Sphingomonadales	M	sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
CMS1_k127_40236_0	745310.G432_02125	1.021e-228	728.0	COG4191@1|root,COG4191@2|Bacteria,1MU55@1224|Proteobacteria,2TXJW@28211|Alphaproteobacteria,2KEK6@204457|Sphingomonadales	204457|Sphingomonadales	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c
CMS1_k127_40236_4	1174684.EBMC1_09424	1.61e-117	382.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria,2K0MW@204457|Sphingomonadales	204457|Sphingomonadales	T	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS1_k127_4046418_0	1331060.RLDS_07085	9.493e-109	358.0	COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,2TSKN@28211|Alphaproteobacteria,2K0E6@204457|Sphingomonadales	204457|Sphingomonadales	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	ppnK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
CMS1_k127_4046418_1	13689.BV96_01966	9.334e-80	271.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,2TQQP@28211|Alphaproteobacteria,2K041@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
CMS1_k127_4047776_2	237727.NAP1_06385	3.381e-93	320.0	COG2114@1|root,COG2114@2|Bacteria,1QWNC@1224|Proteobacteria,2TRQB@28211|Alphaproteobacteria,2K2IP@204457|Sphingomonadales	204457|Sphingomonadales	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
CMS1_k127_4047776_4	1247963.JPHU01000013_gene657	4.023e-16	85.0	2DGJ4@1|root,2ZW79@2|Bacteria,1PBBN@1224|Proteobacteria,2UXQE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4047776_0	383381.EH30_07660	5.052e-172	557.0	COG1574@1|root,COG1574@2|Bacteria,1R53N@1224|Proteobacteria,2VF84@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	metal-dependent hydrolase with the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
CMS1_k127_4047776_3	13690.CP98_00419	2.619e-85	293.0	COG0697@1|root,COG0697@2|Bacteria,1MZXM@1224|Proteobacteria,2TSZM@28211|Alphaproteobacteria,2K256@204457|Sphingomonadales	204457|Sphingomonadales	EG	of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS1_k127_4047776_1	1545915.JROG01000007_gene3047	1.698e-159	505.0	COG1012@1|root,COG1012@2|Bacteria,1MUHV@1224|Proteobacteria,2TSMD@28211|Alphaproteobacteria,2K04G@204457|Sphingomonadales	204457|Sphingomonadales	C	Methylmalonate-semialdehyde dehydrogenase	mmsA	-	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS1_k127_409157_6	685778.AORL01000021_gene364	3.684e-54	193.0	COG1533@1|root,COG1533@2|Bacteria,1MW0H@1224|Proteobacteria,2TQQB@28211|Alphaproteobacteria,2K118@204457|Sphingomonadales	204457|Sphingomonadales	L	DNA repair photolyase	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
CMS1_k127_409157_1	317655.Sala_1180	4.313e-276	859.0	COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,2TR96@28211|Alphaproteobacteria,2K0TE@204457|Sphingomonadales	204457|Sphingomonadales	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	6.2.1.44	ko:K00666,ko:K20034	ko00920,map00920	-	R10820	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
CMS1_k127_409157_0	1545915.JROG01000003_gene1348	0.0	1509.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,2TSCN@28211|Alphaproteobacteria,2K1R8@204457|Sphingomonadales	204457|Sphingomonadales	L	DNA polymerase	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP
CMS1_k127_409157_4	1120705.FG95_02083	2.316e-72	246.0	COG0386@1|root,COG0386@2|Bacteria,1RD1R@1224|Proteobacteria,2U7R3@28211|Alphaproteobacteria,2K47B@204457|Sphingomonadales	204457|Sphingomonadales	O	Belongs to the glutathione peroxidase family	gpo	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
CMS1_k127_409157_3	46429.BV95_02206	3.709e-99	330.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,2TSBE@28211|Alphaproteobacteria,2K04P@204457|Sphingomonadales	204457|Sphingomonadales	V	Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
CMS1_k127_409157_2	1123270.ATUR01000003_gene718	3.042e-201	635.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,2TRBX@28211|Alphaproteobacteria,2K03V@204457|Sphingomonadales	204457|Sphingomonadales	M	ABC-type transport system, involved in lipoprotein release, permease component	-	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
CMS1_k127_409157_5	1545915.JROG01000003_gene1353	1.041e-63	222.0	COG0071@1|root,COG0071@2|Bacteria,1RH2X@1224|Proteobacteria,2U96D@28211|Alphaproteobacteria,2K4JU@204457|Sphingomonadales	204457|Sphingomonadales	O	Belongs to the small heat shock protein (HSP20) family	ibpA	-	-	ko:K04080	-	-	-	-	ko00000,ko03110	-	-	-	HSP20
CMS1_k127_4106413_0	1248760.ANFZ01000004_gene2017	0.0	1151.0	COG0506@1|root,COG4230@1|root,COG0506@2|Bacteria,COG4230@2|Bacteria,1MV93@1224|Proteobacteria,2TQPT@28211|Alphaproteobacteria,2K1B6@204457|Sphingomonadales	204457|Sphingomonadales	CE	Oxidizes proline to glutamate for use as a carbon and nitrogen source	putA	-	1.2.1.88,1.5.5.2	ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh,Pro_dh-DNA_bdg
CMS1_k127_4106413_2	1248916.ANFY01000007_gene2486	2.399e-193	611.0	COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,2TTWK@28211|Alphaproteobacteria,2K0DU@204457|Sphingomonadales	204457|Sphingomonadales	E	Methionine synthase	-	-	-	-	-	-	-	-	-	-	-	-	Meth_synt_2
CMS1_k127_4106413_3	1248917.ANFX01000040_gene766	2.428e-189	595.0	COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,2TTWK@28211|Alphaproteobacteria,2K3CA@204457|Sphingomonadales	204457|Sphingomonadales	E	Cobalamin-independent synthase, Catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Meth_synt_2
CMS1_k127_4106413_10	1479239.JQMU01000001_gene383	2.543e-52	195.0	COG0596@1|root,COG0596@2|Bacteria,1NZXA@1224|Proteobacteria	1224|Proteobacteria	S	Alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS1_k127_4106413_8	1248917.ANFX01000040_gene768	4.159e-79	269.0	COG0346@1|root,COG0346@2|Bacteria,1RAC9@1224|Proteobacteria,2U65N@28211|Alphaproteobacteria,2K485@204457|Sphingomonadales	204457|Sphingomonadales	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS1_k127_4106413_7	1479239.JQMU01000001_gene385	6.469e-100	328.0	COG0655@1|root,COG0655@2|Bacteria,1MW7N@1224|Proteobacteria,2TR4Z@28211|Alphaproteobacteria,2K1XE@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the WrbA family	-	-	1.6.5.2	ko:K03809	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	FMN_red
CMS1_k127_4106413_1	1248916.ANFY01000007_gene2493	0.0	1008.0	COG4774@1|root,COG4774@2|Bacteria,1NMCN@1224|Proteobacteria,2U1C8@28211|Alphaproteobacteria,2K3AZ@204457|Sphingomonadales	204457|Sphingomonadales	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
CMS1_k127_4106413_6	1545915.JROG01000004_gene2621	6.033e-112	368.0	COG1414@1|root,COG1414@2|Bacteria,1QYTM@1224|Proteobacteria,2U04P@28211|Alphaproteobacteria,2K2VC@204457|Sphingomonadales	204457|Sphingomonadales	K	helix_turn_helix isocitrate lyase regulation	-	-	-	ko:K02624	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR
CMS1_k127_4106413_4	1122970.AUHC01000002_gene1435	4.063e-185	585.0	COG1804@1|root,COG1804@2|Bacteria,1P68A@1224|Proteobacteria,2TR4B@28211|Alphaproteobacteria,2K371@204457|Sphingomonadales	204457|Sphingomonadales	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
CMS1_k127_4106413_5	1248917.ANFX01000040_gene773	2.873e-122	397.0	COG0372@1|root,COG0372@2|Bacteria,1MUII@1224|Proteobacteria,2TSDI@28211|Alphaproteobacteria,2K3T2@204457|Sphingomonadales	204457|Sphingomonadales	C	Citrate synthase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Citrate_synt
CMS1_k127_4106413_9	1537715.JQFJ01000005_gene73	6.378e-79	271.0	COG0811@1|root,COG0811@2|Bacteria,1MXHR@1224|Proteobacteria,2TQNN@28211|Alphaproteobacteria,2K907@204457|Sphingomonadales	204457|Sphingomonadales	U	MotA/TolQ/ExbB proton channel family	-	-	-	-	-	-	-	-	-	-	-	-	MotA_ExbB
CMS1_k127_4106413_11	46429.BV95_03519	7.277e-51	188.0	COG0848@1|root,COG0848@2|Bacteria,1RDJZ@1224|Proteobacteria,2U77T@28211|Alphaproteobacteria,2KAKP@204457|Sphingomonadales	204457|Sphingomonadales	U	Biopolymer transport protein ExbD/TolR	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
CMS1_k127_4187187_1	158500.BV97_03110	2.212e-158	508.0	COG0446@1|root,COG3453@1|root,COG0446@2|Bacteria,COG3453@2|Bacteria,1N5MC@1224|Proteobacteria,2TW6Z@28211|Alphaproteobacteria,2K064@204457|Sphingomonadales	204457|Sphingomonadales	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	DUF442,Pyr_redox_2
CMS1_k127_4187187_8	1248760.ANFZ01000018_gene634	1.512e-55	203.0	COG2391@1|root,COG2391@2|Bacteria,1MZC0@1224|Proteobacteria,2U99K@28211|Alphaproteobacteria,2K5CQ@204457|Sphingomonadales	204457|Sphingomonadales	S	transporter component	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	-
CMS1_k127_4187187_7	1248760.ANFZ01000018_gene635	7.208e-60	213.0	COG2391@1|root,COG2391@2|Bacteria,1MZ3A@1224|Proteobacteria,2UCDT@28211|Alphaproteobacteria,2K5A8@204457|Sphingomonadales	204457|Sphingomonadales	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
CMS1_k127_4187187_2	1219035.NT2_26_00030	3.186e-157	500.0	COG0491@1|root,COG0491@2|Bacteria,1MURA@1224|Proteobacteria,2TR1F@28211|Alphaproteobacteria,2K06J@204457|Sphingomonadales	204457|Sphingomonadales	S	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS1_k127_4187187_6	1545915.JROG01000004_gene2061	6.655e-86	290.0	COG0450@1|root,COG0450@2|Bacteria,1MX2B@1224|Proteobacteria,2TT09@28211|Alphaproteobacteria,2K3PT@204457|Sphingomonadales	204457|Sphingomonadales	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	1-cysPrx_C,AhpC-TSA
CMS1_k127_4187187_9	1248760.ANFZ01000018_gene638	6.703e-36	150.0	COG0640@1|root,COG0640@2|Bacteria,1NSV9@1224|Proteobacteria,2UCDX@28211|Alphaproteobacteria,2K63B@204457|Sphingomonadales	204457|Sphingomonadales	K	Bacterial regulatory protein, arsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
CMS1_k127_4187187_4	1479239.JQMU01000001_gene2729	2.305e-109	361.0	COG0500@1|root,COG2226@2|Bacteria,1PPKI@1224|Proteobacteria,2TRIB@28211|Alphaproteobacteria,2K0RA@204457|Sphingomonadales	204457|Sphingomonadales	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS1_k127_4187187_0	392499.Swit_3982	0.0	1121.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,2TRSZ@28211|Alphaproteobacteria,2K046@204457|Sphingomonadales	204457|Sphingomonadales	L	DNA ligase	ligD	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
CMS1_k127_4187187_3	1090319.KE386571_gene3271	1.957e-125	407.0	COG1273@1|root,COG1273@2|Bacteria,1N4UX@1224|Proteobacteria,2TRTI@28211|Alphaproteobacteria,2K1JG@204457|Sphingomonadales	204457|Sphingomonadales	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
CMS1_k127_4187187_11	1144343.PMI41_00794	8.049e-12	69.0	COG5487@1|root,COG5487@2|Bacteria,1NGAH@1224|Proteobacteria,2UJIU@28211|Alphaproteobacteria,43M2Q@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	UPF0391 membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1328
CMS1_k127_4187187_5	2340.JV46_19800	9.628e-90	304.0	COG1796@1|root,COG1796@2|Bacteria,1QF8Z@1224|Proteobacteria,1RRQ5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Helix-hairpin-helix domain	-	-	-	ko:K04477	-	-	-	-	ko00000	-	-	-	HHH_5,HHH_8
CMS1_k127_4195248_3	1408427.JADB01000003_gene1273	3.207e-06	54.0	2AE9K@1|root,3143S@2|Bacteria,1PTGX@1224|Proteobacteria,2V5CG@28211|Alphaproteobacteria,48UFM@772|Bartonellaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4195248_2	1348663.KCH_59080	2.51e-40	162.0	28IKZ@1|root,2Z8MJ@2|Bacteria,2HAVT@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1702)	-	-	-	ko:K21161	ko01059,ko01130,map01059,map01130	M00824	-	-	ko00000,ko00001,ko00002	-	-	-	DUF1702
CMS1_k127_4195248_0	1120956.JHZK01000001_gene3408	2.894e-58	216.0	COG0438@1|root,COG0438@2|Bacteria,1MUYN@1224|Proteobacteria,2U21B@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CMS1_k127_4195248_1	1265503.KB905164_gene1983	2.681e-43	165.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,2Q6IX@267889|Colwelliaceae	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
CMS1_k127_4206534_1	452662.SJA_C1-35020	2.132e-249	779.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,2TSV0@28211|Alphaproteobacteria,2K0BN@204457|Sphingomonadales	204457|Sphingomonadales	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	DUF294,GlnD_UR_UTase,HD
CMS1_k127_4206534_4	579138.Zymop_1212	1.276e-35	143.0	COG1399@1|root,COG1399@2|Bacteria,1N7C2@1224|Proteobacteria,2UC4J@28211|Alphaproteobacteria,2K4K6@204457|Sphingomonadales	204457|Sphingomonadales	S	Uncharacterized ACR, COG1399	-	-	-	-	-	-	-	-	-	-	-	-	DUF177
CMS1_k127_4206534_3	1522072.IL54_3643	2.241e-48	181.0	COG5452@1|root,COG5452@2|Bacteria,1N12T@1224|Proteobacteria,2UCES@28211|Alphaproteobacteria,2K5B4@204457|Sphingomonadales	204457|Sphingomonadales	S	Ubiquinol-cytochrome C chaperone	-	-	-	ko:K17662	-	-	-	-	ko00000,ko03029	-	-	-	Ubiq_cyt_C_chap
CMS1_k127_4206534_2	1502850.FG91_02663	4.121e-58	205.0	COG2913@1|root,COG2913@2|Bacteria,1RHYM@1224|Proteobacteria,2UBU9@28211|Alphaproteobacteria,2K4H5@204457|Sphingomonadales	204457|Sphingomonadales	J	Small protein A (tmRNA-binding)	-	-	-	-	-	-	-	-	-	-	-	-	SmpA_OmlA
CMS1_k127_4206534_0	1248760.ANFZ01000008_gene1615	0.0	1159.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,2TQJT@28211|Alphaproteobacteria,2JZY4@204457|Sphingomonadales	204457|Sphingomonadales	C	Malic enzyme	maeB	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,PTA_PTB,malic
CMS1_k127_4241530_0	1114964.L485_19815	0.0	1029.0	COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,1MUFZ@1224|Proteobacteria,2TRGN@28211|Alphaproteobacteria,2K2HN@204457|Sphingomonadales	204457|Sphingomonadales	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
CMS1_k127_4241530_2	1449076.JOOE01000004_gene213	1.953e-131	428.0	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,2TRQE@28211|Alphaproteobacteria,2K08N@204457|Sphingomonadales	204457|Sphingomonadales	LU	Rossmann fold nucleotide-binding protein involved in DNA uptake	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
CMS1_k127_4241530_4	745310.G432_04065	7.97e-68	237.0	COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,2U7BZ@28211|Alphaproteobacteria,2K0BP@204457|Sphingomonadales	204457|Sphingomonadales	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
CMS1_k127_4241530_3	1114964.L485_19800	7.15e-102	338.0	COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,2TSR7@28211|Alphaproteobacteria,2K1X9@204457|Sphingomonadales	204457|Sphingomonadales	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
CMS1_k127_4241530_1	392499.Swit_3823	3.259e-236	734.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,2TQXI@28211|Alphaproteobacteria,2K08Q@204457|Sphingomonadales	204457|Sphingomonadales	E	5-aminolevulinic acid synthase	-	-	2.3.1.37	ko:K00643	ko00260,ko00860,ko01100,ko01110,map00260,map00860,map01100,map01110	-	R00830	RC00004,RC02815	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS1_k127_4241530_5	1123270.ATUR01000003_gene699	3.36e-54	193.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2TQN9@28211|Alphaproteobacteria,2K27R@204457|Sphingomonadales	204457|Sphingomonadales	E	Threonine dehydratase	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS1_k127_4260584_4	1549858.MC45_12285	3.208e-08	59.0	2B9KF@1|root,322YP@2|Bacteria,1P8XS@1224|Proteobacteria,2UX7H@28211|Alphaproteobacteria,2K64E@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4260584_3	1123270.ATUR01000003_gene1154	1.622e-112	368.0	COG1028@1|root,COG1028@2|Bacteria,1MVYJ@1224|Proteobacteria,2TRJ8@28211|Alphaproteobacteria,2K1AH@204457|Sphingomonadales	204457|Sphingomonadales	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
CMS1_k127_4260584_1	1248760.ANFZ01000009_gene1199	1.699e-178	565.0	COG1960@1|root,COG1960@2|Bacteria,1MUBH@1224|Proteobacteria,2TVBB@28211|Alphaproteobacteria,2K1G8@204457|Sphingomonadales	204457|Sphingomonadales	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS1_k127_4260584_0	1123270.ATUR01000003_gene1157	1.124e-197	622.0	COG1960@1|root,COG1960@2|Bacteria,1MVJC@1224|Proteobacteria,2TUVB@28211|Alphaproteobacteria,2K0FU@204457|Sphingomonadales	204457|Sphingomonadales	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS1_k127_4260584_2	1174684.EBMC1_04599	8.205e-178	569.0	COG2211@1|root,COG2211@2|Bacteria,1MVUM@1224|Proteobacteria,2TVI8@28211|Alphaproteobacteria,2K092@204457|Sphingomonadales	204457|Sphingomonadales	G	COG2211 Na melibiose symporter and related transporters	-	-	-	-	-	-	-	-	-	-	-	-	MFS_2
CMS1_k127_4260584_5	983920.Y88_3250	2.234e-07	52.0	COG1960@1|root,COG1960@2|Bacteria,1MU2V@1224|Proteobacteria,2TSK3@28211|Alphaproteobacteria,2JZVP@204457|Sphingomonadales	204457|Sphingomonadales	I	acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS1_k127_43466_3	1123270.ATUR01000008_gene298	3.577e-45	171.0	COG0363@1|root,COG0363@2|Bacteria,1R5K6@1224|Proteobacteria,2U5C7@28211|Alphaproteobacteria,2JZZT@204457|Sphingomonadales	204457|Sphingomonadales	G	6-phosphogluconolactonase	pgl	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
CMS1_k127_43466_4	1346791.M529_05845	2.242e-32	131.0	COG4967@1|root,COG4967@2|Bacteria,1QUS3@1224|Proteobacteria,2UI9Y@28211|Alphaproteobacteria,2K5TY@204457|Sphingomonadales	204457|Sphingomonadales	NU	Type II secretion system (T2SS), protein I	gspI	-	-	ko:K02458	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSI
CMS1_k127_43466_5	1144307.PMI04_03706	7.239e-30	124.0	COG4970@1|root,COG4970@2|Bacteria,1N9H1@1224|Proteobacteria,2UGK7@28211|Alphaproteobacteria,2K5CF@204457|Sphingomonadales	204457|Sphingomonadales	NU	general secretion pathway protein	gspH	-	-	ko:K02457	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	GspH,N_methyl
CMS1_k127_43466_2	1545915.JROG01000003_gene1239	9.901e-104	353.0	COG1024@1|root,COG1853@1|root,COG1024@2|Bacteria,COG1853@2|Bacteria,1MWF6@1224|Proteobacteria,2TVBC@28211|Alphaproteobacteria,2K0JE@204457|Sphingomonadales	204457|Sphingomonadales	I	enoyl-CoA hydratase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1,Flavin_Reduct
CMS1_k127_43466_0	383381.EH30_01295	9.93e-263	826.0	COG2015@1|root,COG2015@2|Bacteria,1MU82@1224|Proteobacteria,2TSM1@28211|Alphaproteobacteria,2K34X@204457|Sphingomonadales	204457|Sphingomonadales	Q	Alkyl sulfatase dimerisation	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_C,Alkyl_sulf_dimr,Lactamase_B
CMS1_k127_43466_1	383381.EH30_11770	2.328e-129	423.0	COG1960@1|root,COG1960@2|Bacteria,1MW0F@1224|Proteobacteria,2TR9I@28211|Alphaproteobacteria,2K12Q@204457|Sphingomonadales	204457|Sphingomonadales	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS1_k127_4376348_0	1123270.ATUR01000002_gene2366	0.0	1133.0	COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,2TQRQ@28211|Alphaproteobacteria,2K0IA@204457|Sphingomonadales	204457|Sphingomonadales	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
CMS1_k127_4376348_1	926560.KE387027_gene493	2.774e-40	159.0	2EVIQ@1|root,33NYW@2|Bacteria	2|Bacteria	S	Ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase
CMS1_k127_4376348_2	1161401.ASJA01000033_gene3043	7.439e-05	46.0	2DEWU@1|root,2ZPJP@2|Bacteria,1NBPN@1224|Proteobacteria,2VGJK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4409656_3	1479239.JQMU01000001_gene2128	4.679e-60	210.0	COG0798@1|root,COG0798@2|Bacteria,1MUXY@1224|Proteobacteria,2TSVJ@28211|Alphaproteobacteria,2K0F0@204457|Sphingomonadales	204457|Sphingomonadales	P	COG0798 Arsenite efflux pump ACR3 and related permeases	-	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
CMS1_k127_4409656_2	1313172.YM304_02840	1.468e-84	292.0	COG2130@1|root,COG2130@2|Bacteria,2GKR8@201174|Actinobacteria,4CNTP@84992|Acidimicrobiia	84992|Acidimicrobiia	S	N-terminal domain of oxidoreductase	-	-	-	ko:K07119	-	-	-	-	ko00000	-	-	-	ADH_N_2,ADH_zinc_N
CMS1_k127_4409656_4	1537715.JQFJ01000002_gene1719	1.764e-56	210.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,TonB_C
CMS1_k127_4409656_1	1205680.CAKO01000038_gene1996	4.147e-90	306.0	COG2175@1|root,COG2175@2|Bacteria,1MV5K@1224|Proteobacteria,2TQTZ@28211|Alphaproteobacteria,2JSGW@204441|Rhodospirillales	204441|Rhodospirillales	Q	Taurine catabolism dioxygenase TauD, TfdA family	-	-	-	ko:K22303	-	-	-	-	ko00000,ko01000	-	-	-	TauD
CMS1_k127_4409656_0	291985.CCSI01000001_gene2265	8.434e-117	385.0	COG4221@1|root,COG4221@2|Bacteria,1R83E@1224|Proteobacteria,2TVY6@28211|Alphaproteobacteria,2K42C@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS1_k127_4409656_5	1547437.LL06_14175	2.202e-34	138.0	COG1396@1|root,COG1396@2|Bacteria,1MWUC@1224|Proteobacteria,2TU04@28211|Alphaproteobacteria,43I0E@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	K	Helix-turn-helix	MA20_08830	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
CMS1_k127_4499356_1	1192759.AKIB01000030_gene1245	1.291e-152	488.0	COG2850@1|root,COG2850@2|Bacteria,1MW30@1224|Proteobacteria,2U36M@28211|Alphaproteobacteria,2K2U1@204457|Sphingomonadales	204457|Sphingomonadales	S	Cupin superfamily protein	-	-	1.14.11.47	ko:K18850	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Cupin_4
CMS1_k127_4499356_7	1123270.ATUR01000002_gene2044	7.043e-30	119.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2UF6W@28211|Alphaproteobacteria,2K5Z5@204457|Sphingomonadales	204457|Sphingomonadales	K	Cold-shock protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
CMS1_k127_4499356_3	1248760.ANFZ01000018_gene576	1.136e-68	240.0	28IPG@1|root,2Z8PF@2|Bacteria,1P8KM@1224|Proteobacteria,2U8ZT@28211|Alphaproteobacteria,2K4I9@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4499356_6	633149.Bresu_0828	1.236e-35	139.0	COG1226@1|root,3171M@2|Bacteria,1PY9Y@1224|Proteobacteria,2VB0A@28211|Alphaproteobacteria,2KJFJ@204458|Caulobacterales	204458|Caulobacterales	P	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
CMS1_k127_4499356_4	1545915.JROG01000004_gene2015	7.432e-59	208.0	COG4270@1|root,COG4270@2|Bacteria,1N1BK@1224|Proteobacteria,2UD4E@28211|Alphaproteobacteria,2K595@204457|Sphingomonadales	204457|Sphingomonadales	S	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
CMS1_k127_4499356_2	1219035.NT2_01_01070	2.684e-122	399.0	28NMK@1|root,32R9C@2|Bacteria,1R3CH@1224|Proteobacteria,2TS1U@28211|Alphaproteobacteria,2K1MC@204457|Sphingomonadales	204457|Sphingomonadales	U	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	amj	-	-	-	-	-	-	-	-	-	-	-	Amj
CMS1_k127_4499356_0	1088721.NSU_2854	2.858e-220	698.0	COG0471@1|root,COG0490@1|root,COG0471@2|Bacteria,COG0490@2|Bacteria,1MU0K@1224|Proteobacteria,2TSFS@28211|Alphaproteobacteria,2K1E7@204457|Sphingomonadales	204457|Sphingomonadales	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,Na_sulph_symp,TrkA_C
CMS1_k127_4499356_8	1280941.HY2_09460	3.884e-09	65.0	COG5487@1|root,COG5487@2|Bacteria,1NGAH@1224|Proteobacteria	1224|Proteobacteria	S	UPF0391 membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1328
CMS1_k127_4499356_5	1278073.MYSTI_00357	9.402e-57	206.0	COG3158@1|root,COG3158@2|Bacteria,1MUVH@1224|Proteobacteria,42P5Y@68525|delta/epsilon subdivisions,2WJEH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Transport of potassium into the cell	kup	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
CMS1_k127_45104_5	314225.ELI_07485	3.248e-42	157.0	COG4530@1|root,COG4530@2|Bacteria,1N42Z@1224|Proteobacteria,2UDI6@28211|Alphaproteobacteria,2K62H@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (FYDLN_acid)	-	-	-	-	-	-	-	-	-	-	-	-	FYDLN_acid
CMS1_k127_45104_3	161528.ED21_23073	8.962e-98	332.0	COG0628@1|root,COG0628@2|Bacteria,1MXXU@1224|Proteobacteria,2TVPN@28211|Alphaproteobacteria,2K11M@204457|Sphingomonadales	204457|Sphingomonadales	S	permease	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
CMS1_k127_45104_1	1112212.JH584235_gene3058	8.581e-193	607.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,2TTXA@28211|Alphaproteobacteria,2K0J9@204457|Sphingomonadales	204457|Sphingomonadales	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
CMS1_k127_45104_0	317655.Sala_1832	5.001e-242	764.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2TST2@28211|Alphaproteobacteria,2K189@204457|Sphingomonadales	204457|Sphingomonadales	L	Belongs to the DEAD box helicase family	-	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
CMS1_k127_45104_4	1144307.PMI04_01114	1.085e-62	219.0	COG1671@1|root,COG1671@2|Bacteria,1RCZA@1224|Proteobacteria,2U997@28211|Alphaproteobacteria,2K4GS@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the UPF0178 family	-	-	-	ko:K09768	-	-	-	-	ko00000	-	-	-	DUF188
CMS1_k127_45104_2	1174684.EBMC1_11535	2.353e-104	352.0	COG4935@1|root,COG4935@2|Bacteria,1RK8D@1224|Proteobacteria,2UKHW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,P_proprotein
CMS1_k127_4530851_2	1081640.AGFU01000072_gene3456	4.736e-77	262.0	COG2833@1|root,COG2833@2|Bacteria,1MW0V@1224|Proteobacteria,2TQJU@28211|Alphaproteobacteria,2K2JV@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF455
CMS1_k127_4530851_3	1187851.A33M_2585	4.242e-54	194.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,2U6Z9@28211|Alphaproteobacteria,3FD43@34008|Rhodovulum	28211|Alphaproteobacteria	O	AhpC/TSA family	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
CMS1_k127_4530851_0	13689.BV96_01473	8.4e-323	1011.0	COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,2TRY7@28211|Alphaproteobacteria,2K1YP@204457|Sphingomonadales	204457|Sphingomonadales	H	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	-	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
CMS1_k127_4530851_4	317655.Sala_1423	3.489e-45	165.0	COG4430@1|root,COG4430@2|Bacteria,1MYGP@1224|Proteobacteria,2UB8Z@28211|Alphaproteobacteria,2K8BV@204457|Sphingomonadales	204457|Sphingomonadales	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
CMS1_k127_4530851_1	1537715.JQFJ01000002_gene1434	5.474e-193	607.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,2TR87@28211|Alphaproteobacteria,2K0II@204457|Sphingomonadales	204457|Sphingomonadales	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
CMS1_k127_4546564_5	1545915.JROG01000011_gene42	1.318e-66	231.0	COG0491@1|root,COG0491@2|Bacteria,1MUXF@1224|Proteobacteria,2TSYY@28211|Alphaproteobacteria,2K1NF@204457|Sphingomonadales	204457|Sphingomonadales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS1_k127_4546564_4	1123269.NX02_21030	1.773e-101	336.0	COG3820@1|root,COG3820@2|Bacteria,1MVR2@1224|Proteobacteria,2TT8Z@28211|Alphaproteobacteria,2K0D3@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	ko:K09987	-	-	-	-	ko00000	-	-	-	DUF1013
CMS1_k127_4546564_2	1123270.ATUR01000002_gene2183	2.495e-140	454.0	COG0438@1|root,COG0438@2|Bacteria,1MUB7@1224|Proteobacteria,2TQQ0@28211|Alphaproteobacteria,2K08Y@204457|Sphingomonadales	204457|Sphingomonadales	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
CMS1_k127_4546564_0	1123270.ATUR01000002_gene2182	2.304e-145	466.0	COG2908@1|root,COG2908@2|Bacteria,1MVKD@1224|Proteobacteria,2TSEB@28211|Alphaproteobacteria,2K0Q8@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
CMS1_k127_4546564_6	243924.LT42_07945	3.547e-41	156.0	COG0494@1|root,COG0494@2|Bacteria,1N1II@1224|Proteobacteria,1SHPI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	belongs to the nudix hydrolase family	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
CMS1_k127_4546564_1	1096930.L284_15140	1.135e-143	462.0	COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,2TR1J@28211|Alphaproteobacteria,2K115@204457|Sphingomonadales	204457|Sphingomonadales	C	NADPH quinone	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
CMS1_k127_4546564_7	745310.G432_04880	1.15e-16	82.0	COG5509@1|root,COG5509@2|Bacteria,1NG8P@1224|Proteobacteria,2UJB2@28211|Alphaproteobacteria,2K74D@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF1192)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1192
CMS1_k127_4546564_3	1174684.EBMC1_03125	1.26e-133	432.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,2TQUZ@28211|Alphaproteobacteria,2K0MN@204457|Sphingomonadales	204457|Sphingomonadales	O	Belongs to the ClpA ClpB family	clpA	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
CMS1_k127_4551438_1	1545915.JROG01000004_gene1753	6.378e-182	577.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,2TSV0@28211|Alphaproteobacteria,2K0BN@204457|Sphingomonadales	204457|Sphingomonadales	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	DUF294,GlnD_UR_UTase,HD
CMS1_k127_4551438_0	1248760.ANFZ01000002_gene3066	1.042e-226	715.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,2JZZB@204457|Sphingomonadales	204457|Sphingomonadales	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
CMS1_k127_4551438_2	314266.SKA58_03785	6.426e-98	323.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,2TTNS@28211|Alphaproteobacteria,2K1JZ@204457|Sphingomonadales	204457|Sphingomonadales	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
CMS1_k127_4574933_7	745310.G432_17420	1.005e-39	151.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,2TRC1@28211|Alphaproteobacteria,2K0KI@204457|Sphingomonadales	204457|Sphingomonadales	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	RNB,S1
CMS1_k127_4574933_6	237727.NAP1_05430	3.212e-55	199.0	COG0450@1|root,COG0450@2|Bacteria,1QWIV@1224|Proteobacteria,2TWYM@28211|Alphaproteobacteria,2K4E0@204457|Sphingomonadales	204457|Sphingomonadales	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS1_k127_4574933_5	1123270.ATUR01000006_gene227	6.627e-58	206.0	COG0589@1|root,COG0589@2|Bacteria,1R9XB@1224|Proteobacteria,2U59E@28211|Alphaproteobacteria,2K49I@204457|Sphingomonadales	204457|Sphingomonadales	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS1_k127_4574933_2	1346791.M529_06115	3.344e-160	517.0	COG0508@1|root,COG0508@2|Bacteria,1MUGY@1224|Proteobacteria,2TRXM@28211|Alphaproteobacteria,2K0EK@204457|Sphingomonadales	204457|Sphingomonadales	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
CMS1_k127_4574933_8	264203.ZMO0511	3.4e-31	128.0	COG1607@1|root,COG1607@2|Bacteria,1MZAZ@1224|Proteobacteria,2U93J@28211|Alphaproteobacteria,2K4GY@204457|Sphingomonadales	204457|Sphingomonadales	I	acyl-CoA thioester hydrolase	-	-	-	ko:K10806	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT
CMS1_k127_4574933_0	1219045.BV98_002566	5.551e-248	771.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2TR8H@28211|Alphaproteobacteria,2JZWH@204457|Sphingomonadales	204457|Sphingomonadales	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
CMS1_k127_4574933_1	383381.EH30_06110	1.983e-174	549.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,2TQR9@28211|Alphaproteobacteria,2K6X7@204457|Sphingomonadales	204457|Sphingomonadales	EH	Amino-transferase class IV	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
CMS1_k127_4574933_3	1123270.ATUR01000006_gene222	3.98e-102	338.0	2C3PP@1|root,2Z954@2|Bacteria,1MXGR@1224|Proteobacteria,2TS01@28211|Alphaproteobacteria,2K2TC@204457|Sphingomonadales	204457|Sphingomonadales	S	Branched-chain amino acid aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4574933_4	46429.BV95_00721	9.79e-100	331.0	COG0614@1|root,COG0614@2|Bacteria,1RBT1@1224|Proteobacteria,2UZCU@28211|Alphaproteobacteria,2K8MM@204457|Sphingomonadales	204457|Sphingomonadales	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
CMS1_k127_4582209_12	1192759.AKIB01000067_gene3836	1.536e-15	76.0	COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,2TR01@28211|Alphaproteobacteria,2K1JP@204457|Sphingomonadales	204457|Sphingomonadales	O	molecular chaperone	dnaJ_2	-	-	-	-	-	-	-	-	-	-	-	DnaJ,DnaJ_C
CMS1_k127_4582209_9	1174684.EBMC1_02390	2.607e-39	153.0	2DNUQ@1|root,32Z94@2|Bacteria,1N0X4@1224|Proteobacteria,2UD63@28211|Alphaproteobacteria,2K6AA@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF4281)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4281
CMS1_k127_4582209_7	13689.BV96_04220	6.847e-96	316.0	COG0259@1|root,COG0259@2|Bacteria,1NZUU@1224|Proteobacteria,2TT1U@28211|Alphaproteobacteria,2K0J3@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	pdxH	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
CMS1_k127_4582209_6	1545915.JROG01000001_gene374	4.476e-110	361.0	COG0384@1|root,COG0384@2|Bacteria,1R9X4@1224|Proteobacteria,2U4TZ@28211|Alphaproteobacteria,2K01E@204457|Sphingomonadales	204457|Sphingomonadales	S	PhzC PhzF	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
CMS1_k127_4582209_5	1123270.ATUR01000008_gene400	4.462e-129	422.0	COG1680@1|root,COG1680@2|Bacteria,1MY4Y@1224|Proteobacteria,2TYCG@28211|Alphaproteobacteria,2K2G5@204457|Sphingomonadales	204457|Sphingomonadales	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS1_k127_4582209_11	1248760.ANFZ01000006_gene2689	3.042e-27	115.0	28TH0@1|root,2ZFQX@2|Bacteria,1NAIB@1224|Proteobacteria,2UI91@28211|Alphaproteobacteria,2K6T3@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4582209_2	1144307.PMI04_03499	1.015e-186	590.0	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,2TQU7@28211|Alphaproteobacteria,2K1HV@204457|Sphingomonadales	204457|Sphingomonadales	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
CMS1_k127_4582209_8	1248760.ANFZ01000006_gene2795	1.431e-54	192.0	2AMHV@1|root,31CDG@2|Bacteria,1RGVA@1224|Proteobacteria,2U98Q@28211|Alphaproteobacteria,2K54G@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF1153)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1153
CMS1_k127_4582209_10	702113.PP1Y_AT8095	6.909e-32	126.0	COG2261@1|root,COG2261@2|Bacteria,1N3E3@1224|Proteobacteria,2UEBF@28211|Alphaproteobacteria,2K6UA@204457|Sphingomonadales	204457|Sphingomonadales	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
CMS1_k127_4582209_4	1123270.ATUR01000008_gene395	1.693e-136	445.0	COG0845@1|root,COG0845@2|Bacteria,1MXGH@1224|Proteobacteria,2U18A@28211|Alphaproteobacteria,2K0EM@204457|Sphingomonadales	204457|Sphingomonadales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
CMS1_k127_4582209_0	1545915.JROG01000007_gene3243	0.0	1539.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria,2K0BI@204457|Sphingomonadales	204457|Sphingomonadales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
CMS1_k127_4582209_3	745310.G432_10475	6.761e-159	511.0	COG2733@1|root,COG2733@2|Bacteria,1MX3G@1224|Proteobacteria,2U15J@28211|Alphaproteobacteria,2K0FY@204457|Sphingomonadales	204457|Sphingomonadales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF445
CMS1_k127_4582209_1	1123270.ATUR01000008_gene392	1.821e-244	768.0	COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,2TS89@28211|Alphaproteobacteria,2K0WP@204457|Sphingomonadales	204457|Sphingomonadales	E	glutamate dehydrogenase	-	-	1.4.1.2	ko:K15371	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	Bac_GDH
CMS1_k127_4598216_1	1123270.ATUR01000008_gene410	2.136e-128	424.0	COG5388@1|root,COG5388@2|Bacteria,1R74W@1224|Proteobacteria,2UKA0@28211|Alphaproteobacteria,2KDDT@204457|Sphingomonadales	204457|Sphingomonadales	S	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4598216_0	1123270.ATUR01000008_gene392	0.0	1880.0	COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,2TS89@28211|Alphaproteobacteria,2K0WP@204457|Sphingomonadales	204457|Sphingomonadales	E	glutamate dehydrogenase	-	-	1.4.1.2	ko:K15371	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	Bac_GDH
CMS1_k127_4611919_12	1545915.JROG01000003_gene1170	1.05e-39	156.0	COG4206@1|root,COG4206@2|Bacteria,1R1WX@1224|Proteobacteria,2U0GK@28211|Alphaproteobacteria,2K1DC@204457|Sphingomonadales	204457|Sphingomonadales	H	receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
CMS1_k127_4611919_5	1545915.JROG01000003_gene1171	1.398e-92	314.0	COG0625@1|root,COG0625@2|Bacteria,1RA4Y@1224|Proteobacteria,2U5B6@28211|Alphaproteobacteria,2K49D@204457|Sphingomonadales	204457|Sphingomonadales	O	maleylacetoacetate isomerase	-	-	5.2.1.2,5.2.1.4	ko:K01800,ko:K01801	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R03181,R03868	RC00867	ko00000,ko00001,ko00002,ko01000	-	-	-	GST_C_2,GST_N,GST_N_3
CMS1_k127_4611919_6	745310.G432_06855	2.421e-75	264.0	COG1530@1|root,COG1530@2|Bacteria,1RC15@1224|Proteobacteria,2U5PB@28211|Alphaproteobacteria,2K2AZ@204457|Sphingomonadales	204457|Sphingomonadales	J	ribonuclease E activity	-	-	-	-	-	-	-	-	-	-	-	-	RNase_E_G
CMS1_k127_4611919_7	1081640.AGFU01000016_gene1728	1.366e-73	252.0	COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,2TSS5@28211|Alphaproteobacteria,2K3WJ@204457|Sphingomonadales	204457|Sphingomonadales	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
CMS1_k127_4611919_13	1122137.AQXF01000004_gene1788	3.1e-36	140.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,2UBRU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
CMS1_k127_4611919_1	1545915.JROG01000001_gene517	5.805e-228	733.0	COG1629@1|root,COG1629@2|Bacteria,1QVGQ@1224|Proteobacteria,2TWFU@28211|Alphaproteobacteria,2KETH@204457|Sphingomonadales	204457|Sphingomonadales	P	transport	-	-	-	-	-	-	-	-	-	-	-	-	Plug
CMS1_k127_4611919_15	1280949.HAD_04205	1.198e-19	99.0	COG1359@1|root,COG1359@2|Bacteria	2|Bacteria	S	Antibiotic biosynthesis monooxygenase	ycnE	GO:0003674,GO:0003824	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	ABM
CMS1_k127_4611919_2	1123270.ATUR01000002_gene2309	2.296e-118	387.0	COG2850@1|root,COG2850@2|Bacteria,1MXD0@1224|Proteobacteria,2U0CY@28211|Alphaproteobacteria,2K1HD@204457|Sphingomonadales	204457|Sphingomonadales	S	A domain family that is part of the cupin metalloenzyme superfamily.	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_8
CMS1_k127_4611919_3	1545915.JROG01000003_gene1336	2.16e-105	355.0	COG5653@1|root,COG5653@2|Bacteria,1N3Z9@1224|Proteobacteria,2TRT5@28211|Alphaproteobacteria,2K1RW@204457|Sphingomonadales	204457|Sphingomonadales	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
CMS1_k127_4611919_0	1123269.NX02_21760	0.0	1118.0	COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,2TR9G@28211|Alphaproteobacteria,2K0XA@204457|Sphingomonadales	204457|Sphingomonadales	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
CMS1_k127_4611919_4	745310.G432_05730	8.452e-96	323.0	COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,2TTI6@28211|Alphaproteobacteria,2K0EU@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
CMS1_k127_4611919_9	1382356.JQMP01000003_gene1695	1.001e-59	218.0	COG0657@1|root,COG0657@2|Bacteria,2GBCM@200795|Chloroflexi,27YSU@189775|Thermomicrobia	189775|Thermomicrobia	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
CMS1_k127_4611919_10	1545915.JROG01000003_gene1333	6.721e-57	202.0	COG0781@1|root,COG0781@2|Bacteria,1RHFZ@1224|Proteobacteria,2UBQA@28211|Alphaproteobacteria,2K4I2@204457|Sphingomonadales	204457|Sphingomonadales	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
CMS1_k127_4611919_11	627192.SLG_27430	2.173e-52	190.0	COG3812@1|root,COG3812@2|Bacteria,1RGUV@1224|Proteobacteria,2U9BA@28211|Alphaproteobacteria,2K5DU@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF1993)	-	-	-	ko:K09983	-	-	-	-	ko00000	-	-	-	DUF1993
CMS1_k127_4611919_14	1126627.BAWE01000002_gene1295	3.165e-30	130.0	COG4859@1|root,COG4859@2|Bacteria,1QVYY@1224|Proteobacteria,2U8ZR@28211|Alphaproteobacteria,3JYPN@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4611919_8	46429.BV95_01320	7.509e-65	224.0	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,2TSBN@28211|Alphaproteobacteria,2K0A0@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
CMS1_k127_4648028_7	685778.AORL01000016_gene2327	2.164e-26	115.0	COG0583@1|root,COG0583@2|Bacteria,1MXC9@1224|Proteobacteria,2TTTY@28211|Alphaproteobacteria,2K5KF@204457|Sphingomonadales	204457|Sphingomonadales	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4648028_3	1449076.JOOE01000003_gene3455	7.698e-75	255.0	COG1396@1|root,COG1396@2|Bacteria,1RKW7@1224|Proteobacteria,2U9PU@28211|Alphaproteobacteria,2K2H6@204457|Sphingomonadales	204457|Sphingomonadales	K	XRE family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
CMS1_k127_4648028_1	1207055.C100_21790	1.791e-140	456.0	COG0438@1|root,COG0438@2|Bacteria,1R564@1224|Proteobacteria,2TTA7@28211|Alphaproteobacteria,2K1XD@204457|Sphingomonadales	204457|Sphingomonadales	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS1_k127_4648028_4	1219045.BV98_001549	1.097e-35	139.0	COG3737@1|root,COG3737@2|Bacteria,1NPRC@1224|Proteobacteria,2UVP3@28211|Alphaproteobacteria,2K6AR@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF498/DUF598)	-	-	-	-	-	-	-	-	-	-	-	-	DUF498
CMS1_k127_4648028_2	1123270.ATUR01000010_gene1884	3.756e-134	437.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,2TSFW@28211|Alphaproteobacteria,2K18K@204457|Sphingomonadales	204457|Sphingomonadales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
CMS1_k127_4648028_0	1248760.ANFZ01000007_gene2924	3.124e-259	807.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,2TQYG@28211|Alphaproteobacteria,2K1DA@204457|Sphingomonadales	204457|Sphingomonadales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
CMS1_k127_4648028_5	1331060.RLDS_14810	3.343e-34	135.0	COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,2UBZ6@28211|Alphaproteobacteria,2K62B@204457|Sphingomonadales	204457|Sphingomonadales	U	Preprotein translocase subunit YajC	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
CMS1_k127_4648028_6	794846.AJQU01000106_gene2935	3.465e-33	132.0	COG0596@1|root,COG0596@2|Bacteria,1Q47F@1224|Proteobacteria,2U3WB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS1_k127_4662799_5	685778.AORL01000010_gene2825	2.562e-10	60.0	COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,2TR76@28211|Alphaproteobacteria,2K1ZM@204457|Sphingomonadales	204457|Sphingomonadales	S	YjgP YjgQ family	-	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
CMS1_k127_4662799_1	1545915.JROG01000008_gene3486	1.941e-144	468.0	COG3239@1|root,COG3239@2|Bacteria,1MVY5@1224|Proteobacteria,2U156@28211|Alphaproteobacteria,2K0CR@204457|Sphingomonadales	204457|Sphingomonadales	I	Fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
CMS1_k127_4662799_0	1331060.RLDS_08055	5.081e-167	533.0	COG0454@1|root,COG0456@2|Bacteria,1PMA3@1224|Proteobacteria,2TUU2@28211|Alphaproteobacteria,2K0BS@204457|Sphingomonadales	204457|Sphingomonadales	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4662799_2	1545915.JROG01000009_gene2721	1.179e-137	440.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,2TR5J@28211|Alphaproteobacteria,2K0HF@204457|Sphingomonadales	204457|Sphingomonadales	L	exodeoxyribonuclease III	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
CMS1_k127_4662799_3	1219045.BV98_000153	2.619e-44	164.0	COG0316@1|root,COG0316@2|Bacteria,1RHCW@1224|Proteobacteria,2UBR8@28211|Alphaproteobacteria,2K54P@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the HesB IscA family	erpA	-	-	-	-	-	-	-	-	-	-	-	Fe-S_biosyn
CMS1_k127_4662799_4	1248760.ANFZ01000009_gene1031	3.621e-13	69.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2TQZE@28211|Alphaproteobacteria,2K148@204457|Sphingomonadales	204457|Sphingomonadales	M	COG0739 Membrane proteins related to metalloendopeptidases	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CMS1_k127_4665980_10	1545915.JROG01000001_gene523	1.912e-106	356.0	COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,2TTX6@28211|Alphaproteobacteria,2K0B3@204457|Sphingomonadales	204457|Sphingomonadales	S	DNA recombination protein	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
CMS1_k127_4665980_12	555793.WSK_0859	4.741e-77	261.0	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,2U797@28211|Alphaproteobacteria,2K3Y2@204457|Sphingomonadales	204457|Sphingomonadales	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
CMS1_k127_4665980_0	1123270.ATUR01000010_gene1916	0.0	1345.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,2TTI2@28211|Alphaproteobacteria,2K0SD@204457|Sphingomonadales	204457|Sphingomonadales	P	COG1629 Outer membrane receptor proteins, mostly Fe transport	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
CMS1_k127_4665980_11	1550073.JROH01000004_gene2167	2.524e-102	335.0	COG0353@1|root,COG0353@2|Bacteria,1MV9Q@1224|Proteobacteria,2TRZM@28211|Alphaproteobacteria,2K15N@204457|Sphingomonadales	204457|Sphingomonadales	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
CMS1_k127_4665980_6	279238.Saro_2894	1.289e-120	394.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,2TSWX@28211|Alphaproteobacteria,2K0ZM@204457|Sphingomonadales	204457|Sphingomonadales	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
CMS1_k127_4665980_7	1120705.FG95_02776	1.305e-120	395.0	COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,2TR57@28211|Alphaproteobacteria,2K0ZD@204457|Sphingomonadales	204457|Sphingomonadales	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
CMS1_k127_4665980_1	1248760.ANFZ01000006_gene2792	3.744e-310	959.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2TSCY@28211|Alphaproteobacteria,2JZZC@204457|Sphingomonadales	204457|Sphingomonadales	E	Asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
CMS1_k127_4665980_2	1346791.M529_14270	3.349e-157	514.0	COG1269@1|root,COG1269@2|Bacteria,1MXZG@1224|Proteobacteria,2TUKE@28211|Alphaproteobacteria,2K377@204457|Sphingomonadales	204457|Sphingomonadales	C	Transmembrane exosortase (Exosortase_EpsH)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3485,Exosortase_EpsH
CMS1_k127_4665980_9	452662.SJA_C1-15080	9.794e-118	393.0	COG0438@1|root,COG0438@2|Bacteria,1MVIM@1224|Proteobacteria,2TR88@28211|Alphaproteobacteria,2K0WY@204457|Sphingomonadales	204457|Sphingomonadales	M	Glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
CMS1_k127_4665980_3	1545915.JROG01000001_gene477	7.573e-150	488.0	COG2348@1|root,COG2348@2|Bacteria,1MXFY@1224|Proteobacteria,2TTYM@28211|Alphaproteobacteria,2K1U6@204457|Sphingomonadales	204457|Sphingomonadales	V	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
CMS1_k127_4665980_5	1207055.C100_08670	2.917e-131	425.0	COG0726@1|root,COG0726@2|Bacteria,1MWMZ@1224|Proteobacteria,2TVFK@28211|Alphaproteobacteria,2JZZ5@204457|Sphingomonadales	204457|Sphingomonadales	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3473,Polysacc_deac_1
CMS1_k127_4665980_8	13690.CP98_00658	1.357e-119	397.0	COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,2U1EJ@28211|Alphaproteobacteria,2K06V@204457|Sphingomonadales	204457|Sphingomonadales	U	Type II secretory pathway, component ExeA	exeA	-	-	-	-	-	-	-	-	-	-	-	AAA_22
CMS1_k127_4665980_4	1248760.ANFZ01000006_gene2786	1.323e-138	449.0	COG5338@1|root,COG5338@2|Bacteria,1R7QB@1224|Proteobacteria,2TSCP@28211|Alphaproteobacteria,2K2HY@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4667437_2	1545915.JROG01000004_gene2008	2.887e-121	391.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,2TTMF@28211|Alphaproteobacteria,2K056@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	metZ	-	2.5.1.48	ko:K01739,ko:K10764	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
CMS1_k127_4667437_6	1346791.M529_10130	2.036e-54	193.0	COG2967@1|root,COG2967@2|Bacteria,1MZ2Z@1224|Proteobacteria,2U9JM@28211|Alphaproteobacteria,2K4GR@204457|Sphingomonadales	204457|Sphingomonadales	P	protein affecting Mg2 Co2 transport	apaG	-	-	ko:K06195	-	-	-	-	ko00000	-	-	-	DUF525
CMS1_k127_4667437_3	314266.SKA58_10038	1.026e-111	368.0	COG0583@1|root,COG0583@2|Bacteria,1MWY0@1224|Proteobacteria,2U2F2@28211|Alphaproteobacteria,2K1M3@204457|Sphingomonadales	204457|Sphingomonadales	K	Transcriptional regulator	-	-	-	ko:K03566	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
CMS1_k127_4667437_4	1545915.JROG01000010_gene2886	2.753e-109	368.0	COG2367@1|root,COG2367@2|Bacteria,1RAH0@1224|Proteobacteria,2U6HN@28211|Alphaproteobacteria,2K024@204457|Sphingomonadales	204457|Sphingomonadales	V	Beta-lactamase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase2
CMS1_k127_4667437_0	745310.G432_03970	0.0	1075.0	COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,2TQZV@28211|Alphaproteobacteria,2K2GE@204457|Sphingomonadales	204457|Sphingomonadales	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
CMS1_k127_4667437_5	314225.ELI_03555	2.795e-100	331.0	COG5352@1|root,COG5352@2|Bacteria,1RHI6@1224|Proteobacteria,2TS7F@28211|Alphaproteobacteria,2K0A1@204457|Sphingomonadales	204457|Sphingomonadales	S	GcrA cell cycle regulator	-	-	-	ko:K13583	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	GcrA
CMS1_k127_4667437_1	1030157.AFMP01000062_gene3540	1.918e-129	419.0	COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,2TQSY@28211|Alphaproteobacteria,2K23E@204457|Sphingomonadales	204457|Sphingomonadales	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
CMS1_k127_4667437_7	1449076.JOOE01000001_gene2614	1.112e-48	176.0	COG3785@1|root,COG3785@2|Bacteria,1RHM7@1224|Proteobacteria,2U9MS@28211|Alphaproteobacteria,2K54K@204457|Sphingomonadales	204457|Sphingomonadales	S	DNA-binding protein	-	-	-	ko:K11940	-	-	-	-	ko00000,ko03036	-	-	-	YccV-like
CMS1_k127_4678516_2	1248760.ANFZ01000009_gene841	1.989e-06	50.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,2TTBF@28211|Alphaproteobacteria,2K1MX@204457|Sphingomonadales	204457|Sphingomonadales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
CMS1_k127_4678516_0	1123269.NX02_05770	2.487e-186	589.0	COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,2TS98@28211|Alphaproteobacteria,2K035@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
CMS1_k127_4678516_1	1545915.JROG01000003_gene766	2.481e-99	330.0	COG0483@1|root,COG0483@2|Bacteria,1NFR1@1224|Proteobacteria,2U1X2@28211|Alphaproteobacteria,2K2MH@204457|Sphingomonadales	204457|Sphingomonadales	G	inositol monophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Inositol_P
CMS1_k127_4682153_4	1081640.AGFU01000002_gene362	2.783e-94	314.0	COG0861@1|root,COG0861@2|Bacteria,1PN8B@1224|Proteobacteria,2TUV5@28211|Alphaproteobacteria,2K1SQ@204457|Sphingomonadales	204457|Sphingomonadales	P	membrane protein, TerC	-	-	-	-	-	-	-	-	-	-	-	-	TerC
CMS1_k127_4682153_12	1502850.FG91_01792	0.0002405	44.0	COG2329@1|root,COG2329@2|Bacteria,1N078@1224|Proteobacteria,2U99H@28211|Alphaproteobacteria,2K72J@204457|Sphingomonadales	204457|Sphingomonadales	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
CMS1_k127_4682153_0	627192.SLG_39090	2.214e-250	775.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,2TRB4@28211|Alphaproteobacteria,2K1UD@204457|Sphingomonadales	204457|Sphingomonadales	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
CMS1_k127_4682153_9	1174684.EBMC1_06099	1.797e-66	229.0	COG1981@1|root,COG1981@2|Bacteria,1RHGS@1224|Proteobacteria,2U987@28211|Alphaproteobacteria,2K4J9@204457|Sphingomonadales	204457|Sphingomonadales	S	membrane	-	-	-	ko:K08973	-	-	-	-	ko00000	-	-	-	UPF0093
CMS1_k127_4682153_1	1174684.EBMC1_06104	5.457e-164	523.0	COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,2TQQV@28211|Alphaproteobacteria,2JZZP@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
CMS1_k127_4682153_2	1248760.ANFZ01000011_gene193	2.05e-143	458.0	COG1806@1|root,COG1806@2|Bacteria,1MUHU@1224|Proteobacteria,2TT66@28211|Alphaproteobacteria,2K0GA@204457|Sphingomonadales	204457|Sphingomonadales	S	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation	-	-	2.7.11.33,2.7.4.28	ko:K09773	-	-	-	-	ko00000,ko01000	-	-	-	Kinase-PPPase
CMS1_k127_4682153_7	1123269.NX02_25430	1.012e-71	248.0	COG0424@1|root,COG0424@2|Bacteria,1RDA9@1224|Proteobacteria,2U9H5@28211|Alphaproteobacteria,2K2S3@204457|Sphingomonadales	204457|Sphingomonadales	D	Maf-like protein	-	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
CMS1_k127_4682153_3	194867.ALBQ01000014_gene516	1.55e-108	359.0	COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,2TS99@28211|Alphaproteobacteria,2K1U1@204457|Sphingomonadales	204457|Sphingomonadales	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
CMS1_k127_4682153_8	1123270.ATUR01000004_gene1477	8.875e-71	244.0	COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,2U765@28211|Alphaproteobacteria,2K3YB@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
CMS1_k127_4682153_5	1346791.M529_17055	1.679e-92	309.0	COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,2TTFF@28211|Alphaproteobacteria,2K06H@204457|Sphingomonadales	204457|Sphingomonadales	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
CMS1_k127_4682153_6	314225.ELI_12975	6.178e-76	259.0	COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,2TV3J@28211|Alphaproteobacteria,2K2CA@204457|Sphingomonadales	204457|Sphingomonadales	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	-	-	-	-	-	-	-	-	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
CMS1_k127_4682153_10	1123269.NX02_25455	3.334e-38	149.0	COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,2U7B0@28211|Alphaproteobacteria,2K6E5@204457|Sphingomonadales	204457|Sphingomonadales	G	PTS IIA-like nitrogen-regulatory protein PtsN	ptsN	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS_EIIA_2
CMS1_k127_4682153_11	1081640.AGFU01000002_gene373	2.619e-33	130.0	COG2050@1|root,COG2050@2|Bacteria,1RFI9@1224|Proteobacteria,2UF80@28211|Alphaproteobacteria,2K4EA@204457|Sphingomonadales	204457|Sphingomonadales	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
CMS1_k127_4686255_2	1545915.JROG01000004_gene2414	6.778e-64	227.0	COG4235@1|root,COG4235@2|Bacteria,1RB0I@1224|Proteobacteria,2U69S@28211|Alphaproteobacteria,2K4DU@204457|Sphingomonadales	204457|Sphingomonadales	O	Cytochrome c biogenesis factor	-	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	TPR_14,TPR_16,TPR_19
CMS1_k127_4686255_3	452662.SJA_C1-17470	1.632e-48	181.0	COG3088@1|root,COG3088@2|Bacteria,1MZZ5@1224|Proteobacteria,2U96P@28211|Alphaproteobacteria,2K57D@204457|Sphingomonadales	204457|Sphingomonadales	O	subunit of a heme lyase	ccmH	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH
CMS1_k127_4686255_1	452662.SJA_C1-17480	3.588e-67	232.0	COG0526@1|root,COG0526@2|Bacteria,1RI3N@1224|Proteobacteria,2TSEW@28211|Alphaproteobacteria,2K4IY@204457|Sphingomonadales	204457|Sphingomonadales	CO	Alkyl hydroperoxide reductase	ccmG	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,Redoxin
CMS1_k127_4686255_0	1123269.NX02_13255	8.723e-135	436.0	COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,2TRNG@28211|Alphaproteobacteria,2K1MA@204457|Sphingomonadales	204457|Sphingomonadales	O	cytochrome C	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
CMS1_k127_4693521_5	1120705.FG95_01682	4.038e-54	193.0	COG0583@1|root,COG0583@2|Bacteria,1MVA1@1224|Proteobacteria,2TSUS@28211|Alphaproteobacteria,2JZYZ@204457|Sphingomonadales	204457|Sphingomonadales	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	ko:K04761	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
CMS1_k127_4693521_1	551789.ATVJ01000001_gene1985	3.57e-142	461.0	COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,2TSI5@28211|Alphaproteobacteria,43XAX@69657|Hyphomonadaceae	28211|Alphaproteobacteria	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
CMS1_k127_4693521_8	13689.BV96_01637	1.665e-43	162.0	COG2832@1|root,COG2832@2|Bacteria,1N7BI@1224|Proteobacteria,2UFAC@28211|Alphaproteobacteria,2K5PA@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	ko:K09790	-	-	-	-	ko00000	-	-	-	DUF454
CMS1_k127_4693521_0	383381.EH30_15715	2.369e-195	615.0	COG4638@1|root,COG4638@2|Bacteria,1R83A@1224|Proteobacteria,2U4UP@28211|Alphaproteobacteria,2K36D@204457|Sphingomonadales	204457|Sphingomonadales	P	Ring hydroxylating alpha subunit (catalytic domain)	-	-	-	-	-	-	-	-	-	-	-	-	Rieske,Ring_hydroxyl_A
CMS1_k127_4693521_7	1280952.HJA_04336	4.23e-47	176.0	COG1917@1|root,COG1917@2|Bacteria,1N3DQ@1224|Proteobacteria,2UDUW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4693521_11	1479239.JQMU01000001_gene143	4.537e-23	104.0	28YKP@1|root,2ZKEE@2|Bacteria,1NBD7@1224|Proteobacteria,2UHHD@28211|Alphaproteobacteria,2K531@204457|Sphingomonadales	204457|Sphingomonadales	S	Pilus assembly protein PilZ	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
CMS1_k127_4693521_6	582402.Hbal_1065	3.665e-51	185.0	COG0346@1|root,COG0346@2|Bacteria,1RGTU@1224|Proteobacteria,2U9R1@28211|Alphaproteobacteria,43Y6R@69657|Hyphomonadaceae	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS1_k127_4693521_9	172088.AUGA01000020_gene3502	2.519e-33	136.0	COG1309@1|root,COG1309@2|Bacteria,1R9PS@1224|Proteobacteria,2U57B@28211|Alphaproteobacteria,3JSK2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS1_k127_4693521_2	314225.ELI_11090	1.571e-132	428.0	COG5285@1|root,COG5285@2|Bacteria,1QRDD@1224|Proteobacteria,2U0EC@28211|Alphaproteobacteria,2K2NE@204457|Sphingomonadales	204457|Sphingomonadales	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
CMS1_k127_4693521_12	1120705.FG95_00740	2.845e-20	92.0	COG0690@1|root,COG0690@2|Bacteria,1N75P@1224|Proteobacteria,2UF51@28211|Alphaproteobacteria,2K6WV@204457|Sphingomonadales	204457|Sphingomonadales	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
CMS1_k127_4693521_3	1248760.ANFZ01000011_gene212	3.004e-87	290.0	COG0250@1|root,COG0250@2|Bacteria,1MU14@1224|Proteobacteria,2TRID@28211|Alphaproteobacteria,2K0IB@204457|Sphingomonadales	204457|Sphingomonadales	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
CMS1_k127_4693521_4	383381.EH30_12595	1.779e-68	234.0	COG0080@1|root,COG0080@2|Bacteria,1RA2M@1224|Proteobacteria,2U760@28211|Alphaproteobacteria,2K3Z9@204457|Sphingomonadales	204457|Sphingomonadales	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
CMS1_k127_4693521_10	1248760.ANFZ01000011_gene214	1.11e-26	110.0	COG0081@1|root,COG0081@2|Bacteria,1MUE6@1224|Proteobacteria,2TRXP@28211|Alphaproteobacteria,2K0YM@204457|Sphingomonadales	204457|Sphingomonadales	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
CMS1_k127_4694039_2	1502850.FG91_03657	3.396e-174	555.0	COG0438@1|root,COG0438@2|Bacteria,1PDR7@1224|Proteobacteria,2U1R4@28211|Alphaproteobacteria,2K0MZ@204457|Sphingomonadales	204457|Sphingomonadales	M	Glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glycos_transf_1
CMS1_k127_4694039_1	1545915.JROG01000003_gene1201	4.174e-189	602.0	COG3307@1|root,COG3307@2|Bacteria,1PX0E@1224|Proteobacteria,2TT7I@28211|Alphaproteobacteria,2JZV1@204457|Sphingomonadales	204457|Sphingomonadales	M	COG3307 Lipid A core - O-antigen ligase and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
CMS1_k127_4694039_4	1192759.AKIB01000009_gene2606	9.129e-121	395.0	COG4948@1|root,COG4948@2|Bacteria,1MW76@1224|Proteobacteria,2TR16@28211|Alphaproteobacteria,2K34I@204457|Sphingomonadales	204457|Sphingomonadales	M	Mandelate racemase muconate lactonizing enzyme	-	-	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
CMS1_k127_4694039_9	247633.GP2143_13141	2.412e-27	116.0	COG1359@1|root,COG1359@2|Bacteria,1N6JS@1224|Proteobacteria	1224|Proteobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
CMS1_k127_4694039_0	1123270.ATUR01000002_gene2144	2.436e-198	623.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2TQQ7@28211|Alphaproteobacteria,2K0V0@204457|Sphingomonadales	204457|Sphingomonadales	I	Belongs to the thiolase family	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
CMS1_k127_4694039_3	1545915.JROG01000003_gene1200	5.595e-143	463.0	COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria,2TV9F@28211|Alphaproteobacteria,2K1C9@204457|Sphingomonadales	204457|Sphingomonadales	M	mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
CMS1_k127_4694039_5	13689.BV96_01516	1.051e-108	357.0	COG1189@1|root,COG1189@2|Bacteria,1MWP5@1224|Proteobacteria,2TRW9@28211|Alphaproteobacteria,2K0J2@204457|Sphingomonadales	204457|Sphingomonadales	J	Hemolysin	-	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
CMS1_k127_4694039_7	1112214.AHIS01000068_gene3192	6.654e-39	151.0	2BR2H@1|root,31B0W@2|Bacteria,1NY1D@1224|Proteobacteria,2USTP@28211|Alphaproteobacteria,2KDMK@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4694039_8	1123270.ATUR01000004_gene1678	6.644e-31	128.0	2E3B5@1|root,32YAP@2|Bacteria,1N7KQ@1224|Proteobacteria,2UHG1@28211|Alphaproteobacteria,2K43M@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF2721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2721
CMS1_k127_4694039_6	1248760.ANFZ01000009_gene1237	7.048e-79	272.0	COG1648@1|root,COG1648@2|Bacteria,1RFEE@1224|Proteobacteria,2U6CW@28211|Alphaproteobacteria,2K2V1@204457|Sphingomonadales	204457|Sphingomonadales	H	Siroheme synthase	-	-	1.3.1.76,2.1.1.107,4.99.1.4	ko:K02302	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03194,R03947	RC00003,RC00871,RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7
CMS1_k127_4694039_11	1219035.NT2_01_04530	7.347e-14	71.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,2TQPB@28211|Alphaproteobacteria,2JZWD@204457|Sphingomonadales	204457|Sphingomonadales	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
CMS1_k127_4719674_3	745310.G432_05545	2.862e-140	449.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,2TRT0@28211|Alphaproteobacteria,2K03S@204457|Sphingomonadales	204457|Sphingomonadales	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS1_k127_4719674_4	1144305.PMI02_02236	4.795e-131	424.0	COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,2TRQR@28211|Alphaproteobacteria,2K0QA@204457|Sphingomonadales	204457|Sphingomonadales	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
CMS1_k127_4719674_2	1545915.JROG01000007_gene3129	8.258e-158	502.0	COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,2TREC@28211|Alphaproteobacteria,2K0W3@204457|Sphingomonadales	204457|Sphingomonadales	M	Cell wall formation	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
CMS1_k127_4719674_5	13690.CP98_00792	8.907e-92	312.0	COG1589@1|root,COG1589@2|Bacteria,1MY1Q@1224|Proteobacteria,2TQPU@28211|Alphaproteobacteria,2K1JE@204457|Sphingomonadales	204457|Sphingomonadales	D	Cell division protein FtsQ	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
CMS1_k127_4719674_1	1112214.AHIS01000029_gene1150	6.619e-182	577.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,2TQZB@28211|Alphaproteobacteria,2K082@204457|Sphingomonadales	204457|Sphingomonadales	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
CMS1_k127_4719674_0	1123270.ATUR01000002_gene2474	1.638e-207	656.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,2TS1Q@28211|Alphaproteobacteria,2K16V@204457|Sphingomonadales	204457|Sphingomonadales	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
CMS1_k127_4719674_6	1545915.JROG01000007_gene3125	1.196e-61	223.0	COG0457@1|root,COG0457@2|Bacteria,1QNIE@1224|Proteobacteria,2TVQA@28211|Alphaproteobacteria,2K08T@204457|Sphingomonadales	204457|Sphingomonadales	U	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	SPOR,TPR_19
CMS1_k127_4745068_3	1348657.M622_12640	0.0002263	45.0	2DRS8@1|root,33CUB@2|Bacteria,1QV1W@1224|Proteobacteria,2WHUT@28216|Betaproteobacteria,2KXIQ@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4745068_2	935840.JAEQ01000023_gene4327	4.209e-39	150.0	COG3339@1|root,COG3339@2|Bacteria,1MZCY@1224|Proteobacteria,2UC5S@28211|Alphaproteobacteria,43KSD@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
CMS1_k127_4745068_0	1545915.JROG01000003_gene875	4.604e-220	693.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,2K1MV@204457|Sphingomonadales	204457|Sphingomonadales	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
CMS1_k127_4745068_1	1537715.JQFJ01000002_gene1142	2.11e-80	273.0	COG2813@1|root,COG2813@2|Bacteria,1RHAE@1224|Proteobacteria,2U5V5@28211|Alphaproteobacteria,2K42K@204457|Sphingomonadales	204457|Sphingomonadales	J	Protein of unknown function (DUF938)	-	-	-	-	-	-	-	-	-	-	-	-	DUF938
CMS1_k127_4772970_2	1234595.C725_1853	7.295e-18	84.0	COG3367@1|root,COG3367@2|Bacteria,1MVEX@1224|Proteobacteria,2TS0Y@28211|Alphaproteobacteria,4BP6N@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Domain of unknown function (DUF1611_N) Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1611,DUF1611_N
CMS1_k127_4772970_3	1123269.NX02_24635	8.711e-12	66.0	COG0007@1|root,COG0007@2|Bacteria,1MUI0@1224|Proteobacteria,2TRJC@28211|Alphaproteobacteria,2K111@204457|Sphingomonadales	204457|Sphingomonadales	H	Belongs to the precorrin methyltransferase family	-	-	2.1.1.107	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03194	RC00003,RC00871	ko00000,ko00001,ko00002,ko01000	-	-	-	TP_methylase
CMS1_k127_4772970_1	930169.B5T_00144	5.193e-19	98.0	COG2207@1|root,COG2207@2|Bacteria,1MXT9@1224|Proteobacteria,1RXNM@1236|Gammaproteobacteria,1XPQ9@135619|Oceanospirillales	135619|Oceanospirillales	K	AraC-binding-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding_2,HTH_18
CMS1_k127_4772970_0	633149.Bresu_0405	3.416e-308	969.0	COG3595@1|root,COG3595@2|Bacteria,1QZEB@1224|Proteobacteria,2TY79@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP_2,Haemagg_act
CMS1_k127_4781445_7	1123270.ATUR01000002_gene2424	1.015e-144	473.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria,2K0T8@204457|Sphingomonadales	204457|Sphingomonadales	T	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS1_k127_4781445_4	745310.G432_03215	7.219e-184	581.0	COG3288@1|root,COG3288@2|Bacteria,1MVXU@1224|Proteobacteria,2TSZN@28211|Alphaproteobacteria,2K062@204457|Sphingomonadales	204457|Sphingomonadales	C	NAD(P) transhydrogenase subunit alpha	pntAA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
CMS1_k127_4781445_13	1123240.ATVO01000003_gene205	1.375e-44	163.0	COG3288@1|root,COG3288@2|Bacteria,1MZ3E@1224|Proteobacteria,2UBXS@28211|Alphaproteobacteria,2K5AR@204457|Sphingomonadales	204457|Sphingomonadales	C	nad(P) transhydrogenase subunit alpha	pntAB	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
CMS1_k127_4781445_3	1248760.ANFZ01000009_gene1059	1.067e-244	767.0	COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,2TQN1@28211|Alphaproteobacteria,2K05C@204457|Sphingomonadales	204457|Sphingomonadales	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
CMS1_k127_4781445_11	1545915.JROG01000003_gene867	1.663e-91	306.0	COG1794@1|root,COG1794@2|Bacteria,1MV03@1224|Proteobacteria,2U0BH@28211|Alphaproteobacteria,2K0H5@204457|Sphingomonadales	204457|Sphingomonadales	M	aspartate racemase	-	-	5.1.1.13	ko:K01779	ko00250,ko01054,map00250,map01054	-	R00491	RC00302	ko00000,ko00001,ko01000	-	-	-	Asp_Glu_race
CMS1_k127_4781445_6	1248760.ANFZ01000009_gene1041	1.099e-152	493.0	COG3420@1|root,COG3420@2|Bacteria,1QUPB@1224|Proteobacteria,2TTFV@28211|Alphaproteobacteria,2K0ZB@204457|Sphingomonadales	204457|Sphingomonadales	P	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
CMS1_k127_4781445_9	1449076.JOOE01000004_gene39	2.046e-114	378.0	COG2010@1|root,COG2010@2|Bacteria,1QUPA@1224|Proteobacteria,2U3YK@28211|Alphaproteobacteria,2K21S@204457|Sphingomonadales	204457|Sphingomonadales	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CMS1_k127_4781445_12	685035.ADAE01000002_gene2250	1.265e-44	166.0	COG4731@1|root,COG4731@2|Bacteria,1N7E7@1224|Proteobacteria,2UHSI@28211|Alphaproteobacteria,2K60R@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2147
CMS1_k127_4781445_8	1248760.ANFZ01000009_gene1183	8.269e-119	395.0	COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,2TRJ1@28211|Alphaproteobacteria,2K0JH@204457|Sphingomonadales	204457|Sphingomonadales	EGP	Major facilitator superfamily	-	-	-	ko:K07552	-	-	-	-	ko00000,ko02000	2.A.1.2	-	-	MFS_1
CMS1_k127_4781445_5	161528.ED21_21964	1.22e-153	493.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,2TSJN@28211|Alphaproteobacteria,2K1Q4@204457|Sphingomonadales	204457|Sphingomonadales	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
CMS1_k127_4781445_1	1545915.JROG01000001_gene436	3.786e-254	805.0	COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,2U10R@28211|Alphaproteobacteria,2K0G1@204457|Sphingomonadales	204457|Sphingomonadales	P	receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
CMS1_k127_4781445_0	1219035.NT2_01_04050	1.331e-255	792.0	COG3572@1|root,COG3572@2|Bacteria,1MU47@1224|Proteobacteria,2TRPT@28211|Alphaproteobacteria,2K1IW@204457|Sphingomonadales	204457|Sphingomonadales	H	glutamate--cysteine ligase	-	-	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	GCS2
CMS1_k127_4781445_10	1123270.ATUR01000008_gene312	3.494e-93	310.0	COG1238@1|root,COG1238@2|Bacteria,1MWED@1224|Proteobacteria,2U78A@28211|Alphaproteobacteria,2K3NK@204457|Sphingomonadales	204457|Sphingomonadales	S	DedA family	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
CMS1_k127_4781445_2	1123270.ATUR01000008_gene313	2.113e-247	772.0	COG1115@1|root,COG1115@2|Bacteria,1MUI3@1224|Proteobacteria,2TQVA@28211|Alphaproteobacteria,2K1FH@204457|Sphingomonadales	204457|Sphingomonadales	U	alanine symporter	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
CMS1_k127_4781445_14	237727.NAP1_06525	6.164e-11	65.0	COG2130@1|root,COG2130@2|Bacteria,1MUR0@1224|Proteobacteria,2U16B@28211|Alphaproteobacteria,2KEHJ@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF2855)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2855
CMS1_k127_4814125_5	318996.AXAZ01000065_gene5711	2.79e-124	403.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2TQQ7@28211|Alphaproteobacteria,3JR1V@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Belongs to the thiolase family	MA20_05130	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
CMS1_k127_4814125_13	1410668.JNKC01000016_gene993	1.098e-05	48.0	2DES4@1|root,2ZP1M@2|Bacteria,1W3CF@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4814125_2	1123270.ATUR01000002_gene2196	1.437e-188	627.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,2TU11@28211|Alphaproteobacteria,2K0SB@204457|Sphingomonadales	204457|Sphingomonadales	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	glpD	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
CMS1_k127_4814125_1	1174684.EBMC1_02615	5.712e-208	658.0	COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,2TRD7@28211|Alphaproteobacteria,2K01R@204457|Sphingomonadales	204457|Sphingomonadales	C	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	-	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
CMS1_k127_4814125_4	1248760.ANFZ01000011_gene316	5.124e-127	411.0	COG2857@1|root,COG2857@2|Bacteria,1QFU2@1224|Proteobacteria,2TUHX@28211|Alphaproteobacteria,2K07X@204457|Sphingomonadales	204457|Sphingomonadales	C	Cytochrome c1	petC	-	-	ko:K00413	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C1
CMS1_k127_4814125_0	279238.Saro_0677	7.436e-232	722.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,2TSZ3@28211|Alphaproteobacteria,2K0CE@204457|Sphingomonadales	204457|Sphingomonadales	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petB	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
CMS1_k127_4814125_8	745310.G432_02040	4.336e-92	307.0	COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,2TTT2@28211|Alphaproteobacteria,2K1YX@204457|Sphingomonadales	204457|Sphingomonadales	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petA	-	1.10.2.2	ko:K00411	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,UCR_Fe-S_N
CMS1_k127_4814125_11	1123270.ATUR01000002_gene2191	2.469e-54	194.0	COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,2U78W@28211|Alphaproteobacteria,2K57A@204457|Sphingomonadales	204457|Sphingomonadales	J	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
CMS1_k127_4814125_3	1449076.JOOE01000002_gene1463	1.034e-141	454.0	COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,2TQNC@28211|Alphaproteobacteria,2K084@204457|Sphingomonadales	204457|Sphingomonadales	H	coproporphyrinogen III oxidase	hemF	-	1.3.3.3	ko:K00228	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03220	RC00884	ko00000,ko00001,ko00002,ko01000	-	-	-	Coprogen_oxidas
CMS1_k127_4814125_10	685778.AORL01000014_gene2227	1.078e-60	216.0	COG0454@1|root,COG0454@2|Bacteria,1RDGT@1224|Proteobacteria,2TRF5@28211|Alphaproteobacteria,2K22G@204457|Sphingomonadales	204457|Sphingomonadales	K	N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS1_k127_4814125_12	1123270.ATUR01000002_gene2189	7.607e-34	139.0	2EUMT@1|root,33N3N@2|Bacteria,1N09P@1224|Proteobacteria,2UC0R@28211|Alphaproteobacteria,2KDMX@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	GPDPase_memb
CMS1_k127_4814125_6	1248760.ANFZ01000009_gene871	7.137e-99	327.0	COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,2TRXJ@28211|Alphaproteobacteria,2K28T@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
CMS1_k127_4814125_7	1123270.ATUR01000004_gene1566	6.27e-94	313.0	COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,2TU1S@28211|Alphaproteobacteria,2K21H@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
CMS1_k127_4814125_9	1112212.JH584235_gene1323	4.765e-61	212.0	COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,2TU7F@28211|Alphaproteobacteria,2K0K0@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
CMS1_k127_4819502_7	1123269.NX02_28170	5.977e-66	241.0	COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,2TRZA@28211|Alphaproteobacteria,2K10K@204457|Sphingomonadales	204457|Sphingomonadales	M	sugar transferase	-	-	-	ko:K20997	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	Bac_transf
CMS1_k127_4819502_5	551789.ATVJ01000001_gene1920	1.268e-98	330.0	COG2301@1|root,COG2301@2|Bacteria,1MW0A@1224|Proteobacteria,2TTC0@28211|Alphaproteobacteria,43W68@69657|Hyphomonadaceae	28211|Alphaproteobacteria	G	Belongs to the HpcH HpaI aldolase family	citE	-	3.1.2.30,4.1.3.34	ko:K01644,ko:K14451	ko00630,ko01120,ko01200,ko02020,map00630,map01120,map01200,map02020	M00373	R00362,R10612	RC00004,RC00014,RC00067,RC01118	ko00000,ko00001,ko00002,ko01000	-	-	-	HpcH_HpaI
CMS1_k127_4819502_0	629773.AORY01000001_gene2267	1.536e-193	615.0	COG1012@1|root,COG1012@2|Bacteria,1MVGW@1224|Proteobacteria,2TR9T@28211|Alphaproteobacteria,2K0D6@204457|Sphingomonadales	204457|Sphingomonadales	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.68	ko:K00154	-	-	-	-	ko00000,ko01000	-	-	-	Aldedh
CMS1_k127_4819502_1	1121949.AQXT01000002_gene1410	7.141e-165	526.0	COG1804@1|root,COG1804@2|Bacteria,1MX0I@1224|Proteobacteria,2U2RY@28211|Alphaproteobacteria,43ZKU@69657|Hyphomonadaceae	28211|Alphaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
CMS1_k127_4819502_2	1123270.ATUR01000003_gene1205	1.225e-154	504.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2TR6Q@28211|Alphaproteobacteria,2K0U4@204457|Sphingomonadales	204457|Sphingomonadales	L	DEAD DEAH box helicase	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
CMS1_k127_4819502_4	517722.AEUE01000007_gene329	1.611e-126	413.0	COG0463@1|root,COG0463@2|Bacteria,1QTWH@1224|Proteobacteria,2TRNC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS1_k127_4819502_8	517722.AEUE01000007_gene330	3.822e-26	113.0	COG2246@1|root,COG2246@2|Bacteria,1RBFH@1224|Proteobacteria	1224|Proteobacteria	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
CMS1_k127_4819502_3	517722.AEUE01000007_gene331	3.732e-146	479.0	COG1807@1|root,COG1807@2|Bacteria,1NVNI@1224|Proteobacteria,2V5R9@28211|Alphaproteobacteria,2K5BM@204457|Sphingomonadales	204457|Sphingomonadales	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS1_k127_4819502_6	237727.NAP1_01155	3.735e-76	263.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,2TQWP@28211|Alphaproteobacteria,2K18S@204457|Sphingomonadales	204457|Sphingomonadales	E	gamma-glutamyltransferase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
CMS1_k127_483318_2	1545915.JROG01000001_gene427	3.315e-180	572.0	COG0624@1|root,COG0624@2|Bacteria,1MUSU@1224|Proteobacteria,2TRTW@28211|Alphaproteobacteria,2K0AC@204457|Sphingomonadales	204457|Sphingomonadales	E	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases	-	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
CMS1_k127_483318_4	1123270.ATUR01000005_gene462	9.212e-152	487.0	COG3138@1|root,COG3138@2|Bacteria,1MWHC@1224|Proteobacteria,2TREF@28211|Alphaproteobacteria,2K0MB@204457|Sphingomonadales	204457|Sphingomonadales	E	arginine N-succinyltransferase	astA	-	2.3.1.109	ko:K00673	ko00330,ko01100,map00330,map01100	-	R00832	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	AstA
CMS1_k127_483318_1	1248760.ANFZ01000006_gene2738	1.229e-193	611.0	COG3724@1|root,COG3724@2|Bacteria,1MUJV@1224|Proteobacteria,2U0HD@28211|Alphaproteobacteria,2K01P@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2)	astB	-	3.5.3.23	ko:K01484	ko00330,ko01100,map00330,map01100	-	R04189	RC00024	ko00000,ko00001,ko01000	-	-	-	AstB
CMS1_k127_483318_13	1545915.JROG01000001_gene424	1.099e-25	107.0	2A2WM@1|root,30RAQ@2|Bacteria,1NC0Y@1224|Proteobacteria,2UGYZ@28211|Alphaproteobacteria,2K6WP@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_483318_10	1248760.ANFZ01000006_gene2736	3.222e-53	190.0	COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,2U99Y@28211|Alphaproteobacteria,2K54X@204457|Sphingomonadales	204457|Sphingomonadales	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
CMS1_k127_483318_6	983920.Y88_2625	1.345e-85	288.0	COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,2TRJR@28211|Alphaproteobacteria,2K3WZ@204457|Sphingomonadales	204457|Sphingomonadales	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
CMS1_k127_483318_7	1545915.JROG01000001_gene421	1.181e-84	290.0	COG1512@1|root,COG1512@2|Bacteria,1PB41@1224|Proteobacteria,2TUVD@28211|Alphaproteobacteria,2K1AR@204457|Sphingomonadales	204457|Sphingomonadales	S	Methanol dehydrogenase	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
CMS1_k127_483318_8	1120705.FG95_01027	7.385e-72	249.0	COG3762@1|root,COG3762@2|Bacteria,1R61N@1224|Proteobacteria,2U5XG@28211|Alphaproteobacteria,2K470@204457|Sphingomonadales	204457|Sphingomonadales	S	membrane	-	-	-	ko:K08988	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
CMS1_k127_483318_9	291985.CCSI01000008_gene1113	2.38e-68	243.0	COG0494@1|root,COG0494@2|Bacteria,1RE72@1224|Proteobacteria,2U805@28211|Alphaproteobacteria,2K4H0@204457|Sphingomonadales	204457|Sphingomonadales	L	Nudix hydrolase	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
CMS1_k127_483318_12	1123270.ATUR01000005_gene473	3.562e-41	153.0	2C7TH@1|root,32RJS@2|Bacteria,1MZK8@1224|Proteobacteria,2UC2R@28211|Alphaproteobacteria,2K5XZ@204457|Sphingomonadales	204457|Sphingomonadales	S	ETC complex I subunit	-	-	-	-	-	-	-	-	-	-	-	-	ETC_C1_NDUFA4
CMS1_k127_483318_3	314266.SKA58_13713	8.722e-165	525.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,2TSDZ@28211|Alphaproteobacteria,2JZY9@204457|Sphingomonadales	204457|Sphingomonadales	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
CMS1_k127_483318_11	1331060.RLDS_17170	1.098e-42	157.0	COG1605@1|root,COG1605@2|Bacteria,1MZTQ@1224|Proteobacteria,2UCMC@28211|Alphaproteobacteria,2K610@204457|Sphingomonadales	204457|Sphingomonadales	E	chorismate mutase	-	-	5.4.99.5	ko:K04092	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2
CMS1_k127_483318_0	1123269.NX02_27605	4.697e-209	659.0	COG0642@1|root,COG2205@2|Bacteria,1QTVU@1224|Proteobacteria,2TW3R@28211|Alphaproteobacteria,2KEAU@204457|Sphingomonadales	204457|Sphingomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	2CSK_N,HATPase_c
CMS1_k127_483318_5	1123270.ATUR01000005_gene478	1.437e-112	364.0	COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,2TSV8@28211|Alphaproteobacteria,2K0M9@204457|Sphingomonadales	204457|Sphingomonadales	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_4837821_9	685778.AORL01000021_gene550	1.864e-79	269.0	COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,2TRGZ@28211|Alphaproteobacteria,2K16U@204457|Sphingomonadales	204457|Sphingomonadales	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	ko:K11206	-	-	-	-	ko00000,ko01000	-	-	-	CN_hydrolase
CMS1_k127_4837821_16	291985.CCSI01000001_gene2382	4.043e-42	165.0	COG5319@1|root,COG5319@2|Bacteria,1MZN2@1224|Proteobacteria,2UBTA@28211|Alphaproteobacteria,2K54Q@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1178
CMS1_k127_4837821_4	1116232.AHBF01000077_gene8066	1.993e-159	520.0	COG0666@1|root,COG2066@1|root,COG0666@2|Bacteria,COG2066@2|Bacteria,2GKAV@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the glutaminase family	glsA	GO:0003674,GO:0003824,GO:0004359,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006543,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009084,GO:0009987,GO:0016053,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607	3.5.1.2	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	-	R00256,R01579	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Glutaminase
CMS1_k127_4837821_2	1247963.JPHU01000002_gene2435	7.004e-177	569.0	COG2267@1|root,COG3629@1|root,COG2267@2|Bacteria,COG3629@2|Bacteria,1QU9N@1224|Proteobacteria,2TW44@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IT	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CMS1_k127_4837821_11	1219035.NT2_04_02020	5.923e-71	253.0	COG2771@1|root,COG2771@2|Bacteria,1RBMH@1224|Proteobacteria,2U67B@28211|Alphaproteobacteria,2K1GA@204457|Sphingomonadales	204457|Sphingomonadales	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4837821_3	291985.CCSI01000008_gene1051	8.701e-173	544.0	COG0175@1|root,COG0175@2|Bacteria,1MUCZ@1224|Proteobacteria,2TT2D@28211|Alphaproteobacteria,2K1HF@204457|Sphingomonadales	204457|Sphingomonadales	EH	sulfate adenylyltransferase	cysD	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
CMS1_k127_4837821_0	237727.NAP1_12418	0.0	1058.0	COG0529@1|root,COG2895@1|root,COG0529@2|Bacteria,COG2895@2|Bacteria,1MUD9@1224|Proteobacteria,2TQNJ@28211|Alphaproteobacteria,2K22T@204457|Sphingomonadales	204457|Sphingomonadales	P	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysC	-	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU,GTP_EFTU_D2
CMS1_k127_4837821_8	1346791.M529_19865	2.006e-110	364.0	COG1218@1|root,COG1218@2|Bacteria,1MY0Z@1224|Proteobacteria,2TQWF@28211|Alphaproteobacteria,2K0NZ@204457|Sphingomonadales	204457|Sphingomonadales	P	3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase	-	-	3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Inositol_P
CMS1_k127_4837821_22	1331060.RLDS_01705	1.416e-12	74.0	COG2197@1|root,COG2197@2|Bacteria,1MYAW@1224|Proteobacteria,2U9RQ@28211|Alphaproteobacteria,2K5M0@204457|Sphingomonadales	204457|Sphingomonadales	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Sigma70_r4_2
CMS1_k127_4837821_5	1123059.KB823013_gene347	1.062e-144	464.0	COG0235@1|root,COG0235@2|Bacteria,1MWP9@1224|Proteobacteria,2TRMV@28211|Alphaproteobacteria,43W4R@69657|Hyphomonadaceae	28211|Alphaproteobacteria	G	COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
CMS1_k127_4837821_17	314225.ELI_11550	6.85e-38	150.0	28Q4X@1|root,2ZCN0@2|Bacteria,1RA2A@1224|Proteobacteria,2U5RP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4837821_13	279238.Saro_2075	8.946e-66	226.0	2C69U@1|root,32STX@2|Bacteria,1RDUC@1224|Proteobacteria,2U7XY@28211|Alphaproteobacteria,2K4F1@204457|Sphingomonadales	204457|Sphingomonadales	S	Holin of 3TMs, for gene-transfer release	-	-	-	-	-	-	-	-	-	-	-	-	GTA_holin_3TM
CMS1_k127_4837821_10	317655.Sala_1717	3.62e-77	262.0	COG3926@1|root,COG3926@2|Bacteria,1MVXW@1224|Proteobacteria,2U8FG@28211|Alphaproteobacteria,2K3X0@204457|Sphingomonadales	204457|Sphingomonadales	S	secretion activating protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_108,PG_binding_3
CMS1_k127_4837821_19	1207055.C100_19345	1.001e-34	139.0	2D1BA@1|root,32TAA@2|Bacteria,1RJQD@1224|Proteobacteria,2U780@28211|Alphaproteobacteria,2K4RE@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4837821_20	745310.G432_21490	1.746e-26	118.0	2AKHA@1|root,31B98@2|Bacteria,1NQUD@1224|Proteobacteria,2UQN3@28211|Alphaproteobacteria,2K4A9@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4837821_14	1331060.RLDS_25680	1.323e-63	226.0	COG2249@1|root,COG2249@2|Bacteria,1RA5X@1224|Proteobacteria,2U7JU@28211|Alphaproteobacteria,2K5GS@204457|Sphingomonadales	204457|Sphingomonadales	S	Flavodoxin-like fold	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_2
CMS1_k127_4837821_15	13689.BV96_00065	3.883e-63	226.0	COG0589@1|root,COG0589@2|Bacteria,1QD8E@1224|Proteobacteria,2TRQ7@28211|Alphaproteobacteria,2K4W9@204457|Sphingomonadales	204457|Sphingomonadales	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS1_k127_4837821_6	876269.ARWA01000001_gene686	2.469e-130	432.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TR8X@28211|Alphaproteobacteria,3NAFU@45404|Beijerinckiaceae	28211|Alphaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	fixL	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.7.13.3	ko:K14986	ko02020,map02020	M00524	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA,MEDS,PAS,PAS_3,PAS_4,PAS_9
CMS1_k127_4837821_12	1088721.NSU_4754	2.002e-68	239.0	COG4566@1|root,COG4566@2|Bacteria,1N6WR@1224|Proteobacteria,2TUND@28211|Alphaproteobacteria,2K16W@204457|Sphingomonadales	204457|Sphingomonadales	K	part of global network that controls expression of aerobic respiratory terminal oxidases and carbon and nitrogen metabolic enzymes	-	-	-	ko:K14987	ko02020,map02020	M00524	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
CMS1_k127_4837821_21	237727.NAP1_15838	3.796e-14	75.0	COG3197@1|root,COG3197@2|Bacteria,1NG90@1224|Proteobacteria,2UJFJ@28211|Alphaproteobacteria,2K7T0@204457|Sphingomonadales	204457|Sphingomonadales	P	Cytochrome oxidase maturation protein cbb3-type	-	-	-	-	-	-	-	-	-	-	-	-	FixS
CMS1_k127_4837821_1	1248916.ANFY01000014_gene36	4.101e-261	823.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2TR80@28211|Alphaproteobacteria,2K0EB@204457|Sphingomonadales	204457|Sphingomonadales	P	P-type ATPase	-	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
CMS1_k127_4837821_18	46429.BV95_03068	5.549e-37	145.0	COG5456@1|root,COG5456@2|Bacteria,1RHKI@1224|Proteobacteria,2U9GB@28211|Alphaproteobacteria,2K623@204457|Sphingomonadales	204457|Sphingomonadales	P	Integral membrane protein linked to a cation	-	-	-	-	-	-	-	-	-	-	-	-	FixH
CMS1_k127_4837821_7	13689.BV96_00074	3.651e-118	384.0	COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,2TRYB@28211|Alphaproteobacteria,2K0BY@204457|Sphingomonadales	204457|Sphingomonadales	C	Nitrogen fixation protein fixG	ccoG	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
CMS1_k127_4845356_0	671143.DAMO_1138	3.735e-314	986.0	COG3383@1|root,COG3383@2|Bacteria,2NNQ6@2323|unclassified Bacteria	2|Bacteria	C	Molydopterin dinucleotide binding domain	fdxB	-	1.17.1.10,1.17.1.9	ko:K00123,ko:K05299	ko00630,ko00680,ko00720,ko01100,ko01120,ko01200,map00630,map00680,map00720,map01100,map01120,map01200	M00377	R00134,R00519	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_4,Fer4,Fer4_10,Fer4_4,Fer4_6,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CMS1_k127_4845356_1	395964.KE386496_gene2819	2.11e-58	214.0	COG2187@1|root,COG2187@2|Bacteria,1MU9M@1224|Proteobacteria,2TQJN@28211|Alphaproteobacteria,3NAZ0@45404|Beijerinckiaceae	28211|Alphaproteobacteria	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4854256_0	1231190.NA8A_06699	1.338e-226	707.0	COG0446@1|root,COG0446@2|Bacteria,1QSG6@1224|Proteobacteria,2TUP1@28211|Alphaproteobacteria,43HRG@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Pyridine nucleotide-disulphide oxidoreductase	sqr	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
CMS1_k127_4854256_4	34007.IT40_12935	2.484e-26	109.0	COG0607@1|root,32YCZ@2|Bacteria,1N6NN@1224|Proteobacteria,2UFC1@28211|Alphaproteobacteria,2PXX0@265|Paracoccus	28211|Alphaproteobacteria	P	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
CMS1_k127_4854256_3	246200.SPO3315	5.237e-101	337.0	COG0583@1|root,COG0583@2|Bacteria,1MVA1@1224|Proteobacteria,2TSUS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	transcriptional regulator	-	-	-	ko:K04761	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
CMS1_k127_4854256_1	666509.RCA23_c29420	7.493e-168	536.0	COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,2TSI5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
CMS1_k127_4854256_2	246200.SPO3316	3.499e-123	402.0	COG3329@1|root,COG3329@2|Bacteria,1N85P@1224|Proteobacteria,2TRK2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	permease	-	-	-	ko:K07086	-	-	-	-	ko00000	-	-	-	Sbt_1
CMS1_k127_4854256_5	1121939.L861_08470	2.101e-20	93.0	COG1387@1|root,COG1387@2|Bacteria,1MYXV@1224|Proteobacteria,1RWKA@1236|Gammaproteobacteria,1XQDX@135619|Oceanospirillales	135619|Oceanospirillales	L	DNA polymerase alpha chain like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4867392_5	629773.AORY01000002_gene1485	2.202e-103	344.0	COG0583@1|root,COG0583@2|Bacteria,1R69A@1224|Proteobacteria,2U1WB@28211|Alphaproteobacteria,2K166@204457|Sphingomonadales	204457|Sphingomonadales	K	Transcriptional regulator	-	-	-	ko:K03566	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
CMS1_k127_4867392_6	1280953.HOC_08072	3.021e-86	288.0	COG2128@1|root,COG2128@2|Bacteria,1PNA5@1224|Proteobacteria,2U80C@28211|Alphaproteobacteria,4413R@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Carboxymuconolactone decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS1_k127_4867392_7	1090319.KE386571_gene2697	8.646e-73	248.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,2U591@28211|Alphaproteobacteria,2K3YQ@204457|Sphingomonadales	204457|Sphingomonadales	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	Pro_isomerase
CMS1_k127_4867392_0	1123270.ATUR01000002_gene2227	2.081e-197	625.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,2TRWK@28211|Alphaproteobacteria,2K0AK@204457|Sphingomonadales	204457|Sphingomonadales	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
CMS1_k127_4867392_11	1120919.AUBI01000003_gene1732	3.712e-50	183.0	COG1670@1|root,COG1670@2|Bacteria,1RHBD@1224|Proteobacteria,2U925@28211|Alphaproteobacteria,2JTBM@204441|Rhodospirillales	204441|Rhodospirillales	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
CMS1_k127_4867392_13	1545915.JROG01000003_gene737	1.348e-19	94.0	2C2D1@1|root,2ZXR9@2|Bacteria,1NFJM@1224|Proteobacteria,2UGGW@28211|Alphaproteobacteria,2K7CF@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4867392_10	1545915.JROG01000003_gene1539	6.126e-58	204.0	COG5458@1|root,COG5458@2|Bacteria,1N054@1224|Proteobacteria,2UBY1@28211|Alphaproteobacteria,2K5VN@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF1489)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1489
CMS1_k127_4867392_1	766499.C357_16791	8.43e-139	467.0	COG0671@1|root,COG0671@2|Bacteria,1PMVX@1224|Proteobacteria,2TTJS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	phosphoesterase, PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4867392_4	1545915.JROG01000001_gene156	7.933e-113	371.0	COG2816@1|root,COG2816@2|Bacteria,1QGCX@1224|Proteobacteria,2TVMG@28211|Alphaproteobacteria,2K1ZX@204457|Sphingomonadales	204457|Sphingomonadales	L	Belongs to the Nudix hydrolase family	-	-	3.6.1.22	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	-	R00103,R03004,R11104	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX,NUDIX-like,zf-NADH-PPase
CMS1_k127_4867392_2	1545915.JROG01000001_gene155	1.678e-135	446.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,2TS9A@28211|Alphaproteobacteria,2K18D@204457|Sphingomonadales	204457|Sphingomonadales	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS1_k127_4867392_3	1123270.ATUR01000002_gene2222	3.407e-116	396.0	COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,2TQVX@28211|Alphaproteobacteria,2K0ZZ@204457|Sphingomonadales	204457|Sphingomonadales	L	glycosylase	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
CMS1_k127_4867392_9	1123270.ATUR01000002_gene2221	1.965e-62	221.0	COG5389@1|root,COG5389@2|Bacteria,1N82D@1224|Proteobacteria,2UFA9@28211|Alphaproteobacteria,2K49H@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
CMS1_k127_4867392_8	1545915.JROG01000001_gene152	3.923e-64	228.0	COG1651@1|root,COG1651@2|Bacteria,1RFF4@1224|Proteobacteria,2U5BN@28211|Alphaproteobacteria,2K57Q@204457|Sphingomonadales	204457|Sphingomonadales	M	Protein-disulfide isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
CMS1_k127_4867392_12	1545915.JROG01000001_gene151	5.842e-38	145.0	COG1651@1|root,COG1651@2|Bacteria,1RBWK@1224|Proteobacteria,2U6HJ@28211|Alphaproteobacteria,2K3W7@204457|Sphingomonadales	204457|Sphingomonadales	M	Protein-disulfide isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
CMS1_k127_487083_0	383381.EH30_02485	9.146e-86	301.0	COG0457@1|root,COG0457@2|Bacteria,1R530@1224|Proteobacteria,2TWPW@28211|Alphaproteobacteria,2K34N@204457|Sphingomonadales	204457|Sphingomonadales	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_487083_1	1123269.NX02_13440	1.504e-34	135.0	29WZ9@1|root,30IMG@2|Bacteria,1MXG3@1224|Proteobacteria,2U1X3@28211|Alphaproteobacteria,2K0FH@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4331
CMS1_k127_4883658_0	1248760.ANFZ01000009_gene835	8.334e-265	831.0	COG1752@1|root,COG1752@2|Bacteria,1MWH2@1224|Proteobacteria,2TU16@28211|Alphaproteobacteria,2K0ET@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF3376)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3376,Patatin
CMS1_k127_4883658_1	392499.Swit_4092	6.519e-222	694.0	COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,2TS6F@28211|Alphaproteobacteria,2K1F3@204457|Sphingomonadales	204457|Sphingomonadales	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
CMS1_k127_4883658_10	1123270.ATUR01000002_gene2503	2.106e-52	190.0	COG1286@1|root,COG1286@2|Bacteria,1REF7@1224|Proteobacteria,2VA4D@28211|Alphaproteobacteria,2K52S@204457|Sphingomonadales	204457|Sphingomonadales	S	Colicin V production protein	-	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
CMS1_k127_4883658_12	745310.G432_01700	1.021e-36	143.0	COG0822@1|root,COG0822@2|Bacteria,1RDGB@1224|Proteobacteria,2U74A@28211|Alphaproteobacteria,2K54B@204457|Sphingomonadales	204457|Sphingomonadales	C	NifU homolog involved in Fe-S cluster formation	-	-	-	-	-	-	-	-	-	-	-	-	NifU_N
CMS1_k127_4883658_2	1545915.JROG01000003_gene635	9.202e-218	690.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,2TRC5@28211|Alphaproteobacteria,2K1PS@204457|Sphingomonadales	204457|Sphingomonadales	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455,ko:K11747	-	-	-	-	ko00000,ko02000	2.A.37,2.A.37.1.2	-	-	Na_H_Exchanger,TrkA_N
CMS1_k127_4883658_6	13690.CP98_01400	1.482e-146	472.0	COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,2TRDA@28211|Alphaproteobacteria,2K0HR@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
CMS1_k127_4883658_9	1248760.ANFZ01000009_gene1121	1.202e-68	238.0	COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,2U76C@28211|Alphaproteobacteria,2K4PP@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
CMS1_k127_4883658_4	1123270.ATUR01000002_gene2509	5.231e-160	525.0	2BWFC@1|root,33R2I@2|Bacteria,1R42X@1224|Proteobacteria,2U4BF@28211|Alphaproteobacteria,2K0XT@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4883658_7	1248760.ANFZ01000009_gene1124	5.529e-108	357.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,2TRAA@28211|Alphaproteobacteria,2K25K@204457|Sphingomonadales	204457|Sphingomonadales	L	Belongs to the 'phage' integrase family	xerC	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
CMS1_k127_4883658_5	1545915.JROG01000003_gene934	1.519e-149	478.0	COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,2TR6V@28211|Alphaproteobacteria,2K0BW@204457|Sphingomonadales	204457|Sphingomonadales	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
CMS1_k127_4883658_3	1545915.JROG01000003_gene935	6.155e-194	616.0	COG4784@1|root,COG4784@2|Bacteria,1QTT7@1224|Proteobacteria,2TTU7@28211|Alphaproteobacteria,2K1IX@204457|Sphingomonadales	204457|Sphingomonadales	S	peptidase M48, Ste24p	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M48
CMS1_k127_4883658_13	237727.NAP1_04135	1.531e-14	74.0	COG3847@1|root,COG3847@2|Bacteria,1Q1G3@1224|Proteobacteria,2V11R@28211|Alphaproteobacteria,2K7TI@204457|Sphingomonadales	204457|Sphingomonadales	U	Flp pilus assembly protein, pilin Flp	-	-	-	ko:K02651	ko04112,map04112	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	Flp_Fap
CMS1_k127_4883658_14	1207055.C100_20275	1.16e-09	61.0	COG3847@1|root,COG3847@2|Bacteria,1NNS6@1224|Proteobacteria,2UMCC@28211|Alphaproteobacteria,2K7R4@204457|Sphingomonadales	204457|Sphingomonadales	U	Flp/Fap pilin component	-	-	-	ko:K02651	ko04112,map04112	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	Flp_Fap
CMS1_k127_4883658_11	1537715.JQFJ01000002_gene1516	3.885e-44	165.0	COG0494@1|root,COG0494@2|Bacteria,1RCZM@1224|Proteobacteria,2U7A4@28211|Alphaproteobacteria,2K55B@204457|Sphingomonadales	204457|Sphingomonadales	L	Belongs to the Nudix hydrolase family	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
CMS1_k127_4883658_8	13689.BV96_01488	1.812e-70	246.0	COG0500@1|root,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,2TRFS@28211|Alphaproteobacteria,2K0V6@204457|Sphingomonadales	204457|Sphingomonadales	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
CMS1_k127_4886888_0	1545915.JROG01000004_gene1881	2.772e-186	591.0	COG0433@1|root,COG0433@2|Bacteria,1MUSH@1224|Proteobacteria,2TUN9@28211|Alphaproteobacteria,2K091@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function DUF87	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853,DUF87
CMS1_k127_4886888_3	1248760.ANFZ01000019_gene1805	3.421e-84	287.0	2AFUA@1|root,315WQ@2|Bacteria,1NHGB@1224|Proteobacteria,2TQWW@28211|Alphaproteobacteria,2JZXR@204457|Sphingomonadales	204457|Sphingomonadales	S	Putative transmembrane protein (Alph_Pro_TM)	-	-	-	-	-	-	-	-	-	-	-	-	Alph_Pro_TM
CMS1_k127_4886888_1	1248760.ANFZ01000019_gene1806	1.135e-141	454.0	COG0730@1|root,COG0730@2|Bacteria,1MWX2@1224|Proteobacteria,2TRIC@28211|Alphaproteobacteria,2K1QQ@204457|Sphingomonadales	204457|Sphingomonadales	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
CMS1_k127_4886888_4	1112212.JH584235_gene2183	1.977e-34	146.0	2AKVH@1|root,31BNP@2|Bacteria,1N2QY@1224|Proteobacteria,2UDTI@28211|Alphaproteobacteria,2K69U@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4886888_2	627192.SLG_31600	1.011e-136	451.0	COG1215@1|root,COG1215@2|Bacteria,1P7GR@1224|Proteobacteria,2TS4P@28211|Alphaproteobacteria,2K0A7@204457|Sphingomonadales	204457|Sphingomonadales	M	COG1215 Glycosyltransferases, probably involved in cell wall biogenesis	-	-	-	ko:K11740	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3
CMS1_k127_4886888_5	392499.Swit_3179	1.076e-22	103.0	2EP5S@1|root,33GSG@2|Bacteria,1NI0K@1224|Proteobacteria,2UK2B@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4890825_6	1123269.NX02_22905	8.61e-12	66.0	COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,2TRSR@28211|Alphaproteobacteria,2JZY8@204457|Sphingomonadales	204457|Sphingomonadales	S	peptidase U62, modulator of DNA gyrase	tldD	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
CMS1_k127_4890825_4	1090320.KB900605_gene1270	1.929e-26	119.0	COG4391@1|root,COG4391@2|Bacteria,1N7F4@1224|Proteobacteria,2UHY4@28211|Alphaproteobacteria,2K6U4@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	zf-CHCC
CMS1_k127_4890825_8	1192759.AKIB01000004_gene544	3.202e-08	62.0	2EKFG@1|root,33E5M@2|Bacteria,1NJ6W@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF4402)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4402
CMS1_k127_4890825_7	290317.Cpha266_1758	2.483e-10	68.0	2EKFG@1|root,33E5M@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4402)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4402
CMS1_k127_4890825_5	383381.EH30_13595	4.977e-15	82.0	2D4N4@1|root,32THB@2|Bacteria,1P3T6@1224|Proteobacteria,2UU52@28211|Alphaproteobacteria,2KB4Q@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF4402)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4402
CMS1_k127_4890825_2	1112216.JH594425_gene1083	3.856e-153	489.0	COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,2TR2Q@28211|Alphaproteobacteria,2K06G@204457|Sphingomonadales	204457|Sphingomonadales	V	ABC-type multidrug transport system, ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_4890825_1	1248760.ANFZ01000002_gene3049	7.129e-276	858.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,2TS0E@28211|Alphaproteobacteria,2JZXW@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
CMS1_k127_4890825_0	1537715.JQFJ01000002_gene2186	1e-323	1004.0	COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,2TS4D@28211|Alphaproteobacteria,2K1S8@204457|Sphingomonadales	204457|Sphingomonadales	S	COG2366 Protein related to penicillin acylase	-	-	3.5.1.97	ko:K07116	-	-	-	-	ko00000,ko01000	-	-	-	Penicil_amidase
CMS1_k127_4890825_3	1123270.ATUR01000004_gene1740	4.152e-60	211.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,2TRKI@28211|Alphaproteobacteria,2K00X@204457|Sphingomonadales	204457|Sphingomonadales	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
CMS1_k127_4910548_6	1123270.ATUR01000006_gene92	1.544e-89	301.0	COG1028@1|root,COG1028@2|Bacteria,1RAEZ@1224|Proteobacteria,2U7DM@28211|Alphaproteobacteria,2K1FQ@204457|Sphingomonadales	204457|Sphingomonadales	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
CMS1_k127_4910548_5	1123270.ATUR01000006_gene93	3.283e-93	312.0	COG3022@1|root,COG3022@2|Bacteria,1MUAF@1224|Proteobacteria,2TS11@28211|Alphaproteobacteria,2K0M3@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the UPF0246 family	-	-	-	ko:K09861	-	-	-	-	ko00000	-	-	-	H2O2_YaaD
CMS1_k127_4910548_11	1123269.NX02_15450	1.331e-51	200.0	COG0457@1|root,COG0457@2|Bacteria,1Q7UR@1224|Proteobacteria,2U8BX@28211|Alphaproteobacteria,2K0N1@204457|Sphingomonadales	204457|Sphingomonadales	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
CMS1_k127_4910548_9	13689.BV96_01843	7.2e-74	251.0	COG1522@1|root,COG1522@2|Bacteria,1MXVU@1224|Proteobacteria,2TTCK@28211|Alphaproteobacteria,2K44J@204457|Sphingomonadales	204457|Sphingomonadales	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24
CMS1_k127_4910548_2	1123270.ATUR01000006_gene96	2.844e-125	420.0	COG0642@1|root,COG2205@2|Bacteria,1R692@1224|Proteobacteria,2U480@28211|Alphaproteobacteria,2K18H@204457|Sphingomonadales	204457|Sphingomonadales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HisKA
CMS1_k127_4910548_3	158500.BV97_01298	1.525e-108	362.0	COG0726@1|root,COG0726@2|Bacteria,1MX6K@1224|Proteobacteria,2TRGJ@28211|Alphaproteobacteria,2K04F@204457|Sphingomonadales	204457|Sphingomonadales	G	lipopolysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4910548_8	1123270.ATUR01000010_gene1909	1.899e-76	261.0	28JRZ@1|root,2Z9HI@2|Bacteria,1R52Z@1224|Proteobacteria,2U6D6@28211|Alphaproteobacteria,2K3XN@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF4126)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4126
CMS1_k127_4910548_7	1248760.ANFZ01000002_gene3145	5.681e-77	268.0	COG1051@1|root,COG1051@2|Bacteria,1QUPQ@1224|Proteobacteria,2TW3M@28211|Alphaproteobacteria,2K0RT@204457|Sphingomonadales	204457|Sphingomonadales	F	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS1_k127_4910548_1	1248760.ANFZ01000002_gene3177	1.388e-130	419.0	COG1738@1|root,COG1738@2|Bacteria,1NIPE@1224|Proteobacteria,2TTZV@28211|Alphaproteobacteria,2K1FS@204457|Sphingomonadales	204457|Sphingomonadales	S	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
CMS1_k127_4910548_12	1137281.D778_00050	1.359e-29	123.0	2C7KN@1|root,32RJD@2|Bacteria,4NR1V@976|Bacteroidetes,1I42C@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4910548_4	13689.BV96_03416	5.003e-94	311.0	COG0678@1|root,COG0678@2|Bacteria,1MU0H@1224|Proteobacteria,2TU5A@28211|Alphaproteobacteria,2K3FH@204457|Sphingomonadales	204457|Sphingomonadales	O	Peroxiredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Redoxin
CMS1_k127_4910548_10	1123270.ATUR01000003_gene861	8.07e-67	231.0	COG1514@1|root,COG1514@2|Bacteria,1RIHA@1224|Proteobacteria,2UAUZ@28211|Alphaproteobacteria,2K46A@204457|Sphingomonadales	204457|Sphingomonadales	J	2'-5' RNA ligase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
CMS1_k127_4910548_0	13689.BV96_03418	2.09e-139	449.0	COG0446@1|root,COG0446@2|Bacteria,1NR3M@1224|Proteobacteria,2TS0K@28211|Alphaproteobacteria,2K12H@204457|Sphingomonadales	204457|Sphingomonadales	S	pyridine nucleotide-disulfide oxidoreductase	-	-	1.18.1.3	ko:K00529	ko00071,ko00360,ko01120,ko01220,map00071,map00360,map01120,map01220	M00545	R02000,R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Pyr_redox_2,Reductase_C
CMS1_k127_4922623_2	1123270.ATUR01000003_gene805	4.22e-124	405.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2TRMU@28211|Alphaproteobacteria,2K09N@204457|Sphingomonadales	204457|Sphingomonadales	NU	General secretion pathway protein E	gspE	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
CMS1_k127_4922623_0	1248760.ANFZ01000006_gene2428	0.0	1076.0	COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,1MX4K@1224|Proteobacteria,2TV3K@28211|Alphaproteobacteria,2JZXE@204457|Sphingomonadales	204457|Sphingomonadales	P	COG1629 Outer membrane receptor proteins, mostly Fe transport	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
CMS1_k127_4922623_1	1545915.JROG01000007_gene3097	1.941e-205	651.0	COG2182@1|root,COG2182@2|Bacteria,1MU3H@1224|Proteobacteria,2U0ZI@28211|Alphaproteobacteria,2K10P@204457|Sphingomonadales	204457|Sphingomonadales	G	Extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4922623_3	1248760.ANFZ01000006_gene2426	2.146e-21	97.0	COG0457@1|root,COG0457@2|Bacteria,1NPY1@1224|Proteobacteria,2UKIN@28211|Alphaproteobacteria,2K7MN@204457|Sphingomonadales	204457|Sphingomonadales	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4940118_1	1192759.AKIB01000050_gene1051	5.996e-107	355.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,2TSTN@28211|Alphaproteobacteria,2K0RQ@204457|Sphingomonadales	204457|Sphingomonadales	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
CMS1_k127_4940118_5	1120705.FG95_03491	8.669e-29	121.0	2EKFG@1|root,33E5M@2|Bacteria,1NJ6W@1224|Proteobacteria,2UJAN@28211|Alphaproteobacteria,2K84W@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF4402)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4402
CMS1_k127_4940118_2	1174684.EBMC1_06024	4.286e-94	316.0	COG3121@1|root,COG3121@2|Bacteria,1RFSJ@1224|Proteobacteria,2U926@28211|Alphaproteobacteria,2K4YS@204457|Sphingomonadales	204457|Sphingomonadales	NU	COG3121 P pilus assembly protein, chaperone PapD	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4940118_0	1502850.FG91_01805	2.097e-291	923.0	COG3188@1|root,COG3188@2|Bacteria,1R6ZJ@1224|Proteobacteria,2U0NW@28211|Alphaproteobacteria,2K2TI@204457|Sphingomonadales	204457|Sphingomonadales	NU	usher protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS1_k127_4940118_3	1280950.HJO_07752	3.66e-71	252.0	COG2021@1|root,COG2021@2|Bacteria,1QU6N@1224|Proteobacteria,2TXCU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
CMS1_k127_4940118_4	314225.ELI_02455	7.138e-45	174.0	COG1597@1|root,COG1597@2|Bacteria,1RIPU@1224|Proteobacteria,2UHBV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
CMS1_k127_4942613_6	1248760.ANFZ01000009_gene1284	2.607e-38	145.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,2TSU8@28211|Alphaproteobacteria,2K0KF@204457|Sphingomonadales	204457|Sphingomonadales	S	Polyphosphate kinase 2 (PPK2)	ppk2	-	-	-	-	-	-	-	-	-	-	-	PPK2
CMS1_k127_4942613_1	1545915.JROG01000003_gene1306	4.794e-220	702.0	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,2TRDB@28211|Alphaproteobacteria,2K0PK@204457|Sphingomonadales	204457|Sphingomonadales	M	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT
CMS1_k127_4942613_3	279238.Saro_1443	1.94e-135	436.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,2TR5W@28211|Alphaproteobacteria,2K09B@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
CMS1_k127_4942613_4	1123270.ATUR01000005_gene436	2.508e-73	255.0	COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,2U71I@28211|Alphaproteobacteria,2K3YM@204457|Sphingomonadales	204457|Sphingomonadales	O	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
CMS1_k127_4942613_5	1123270.ATUR01000005_gene435	5.68e-65	228.0	COG3216@1|root,COG3216@2|Bacteria,1RGV6@1224|Proteobacteria,2UB7Z@28211|Alphaproteobacteria,2K4SW@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	ko:K09928	-	-	-	-	ko00000	-	-	-	DUF2062
CMS1_k127_4942613_0	627192.SLG_15190	2.294e-291	915.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,2K0WG@204457|Sphingomonadales	204457|Sphingomonadales	T	Histidine kinase	-	-	2.7.13.3	ko:K13587	ko02020,ko04112,map02020,map04112	M00512	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_4,PAS_8,Response_reg
CMS1_k127_4942613_2	1174684.EBMC1_15112	2.441e-194	610.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,2TRPR@28211|Alphaproteobacteria,2K1TR@204457|Sphingomonadales	204457|Sphingomonadales	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
CMS1_k127_4942613_7	194867.ALBQ01000018_gene2458	5.833e-38	145.0	COG0625@1|root,COG0625@2|Bacteria,1MXHH@1224|Proteobacteria,2TVGY@28211|Alphaproteobacteria,2K0MF@204457|Sphingomonadales	204457|Sphingomonadales	O	Glutathione S-transferase	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N
CMS1_k127_4952458_1	1335760.ASTG01000006_gene1463	2.794e-98	323.0	COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,2TRQG@28211|Alphaproteobacteria,2K02F@204457|Sphingomonadales	204457|Sphingomonadales	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N
CMS1_k127_4952458_5	318586.Pden_3158	1.523e-13	74.0	2E5TA@1|root,330HM@2|Bacteria,1N9DH@1224|Proteobacteria,2UGMM@28211|Alphaproteobacteria,2PXA4@265|Paracoccus	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4952458_4	1188256.BASI01000001_gene321	6.148e-24	103.0	COG2929@1|root,COG2929@2|Bacteria,1N83Z@1224|Proteobacteria,2UGAH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
CMS1_k127_4952458_3	1248760.ANFZ01000006_gene2573	1.97e-31	126.0	COG3514@1|root,COG3514@2|Bacteria,1PSWF@1224|Proteobacteria,2UIST@28211|Alphaproteobacteria,2K6FN@204457|Sphingomonadales	204457|Sphingomonadales	S	BrnA antitoxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	BrnA_antitoxin
CMS1_k127_4952458_0	501479.ACNW01000098_gene1158	1.787e-144	471.0	COG2271@1|root,COG2271@2|Bacteria,1QXW3@1224|Proteobacteria,2TXD4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_4952458_2	517722.AEUE01000003_gene1442	9.019e-59	205.0	COG3665@1|root,COG3665@2|Bacteria,1N9DM@1224|Proteobacteria,2TSFM@28211|Alphaproteobacteria,2K0VD@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF1989)	-	-	-	ko:K09967	-	-	-	-	ko00000	-	-	-	DUF1989
CMS1_k127_495400_1	1248760.ANFZ01000009_gene913	1.043e-113	371.0	COG2124@1|root,COG2124@2|Bacteria,1MV75@1224|Proteobacteria,2TSV7@28211|Alphaproteobacteria,2K088@204457|Sphingomonadales	204457|Sphingomonadales	Q	Cytochrome p450	-	-	-	-	-	-	-	-	-	-	-	-	p450
CMS1_k127_495400_2	565045.NOR51B_1489	3.955e-65	231.0	2F1PW@1|root,33UQ6@2|Bacteria,1RHX8@1224|Proteobacteria,1SPAN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_495400_4	1121948.AUAC01000006_gene530	8.577e-18	87.0	2E7Y2@1|root,32RX6@2|Bacteria,1R3BP@1224|Proteobacteria,2U005@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4345)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4345
CMS1_k127_495400_0	1248760.ANFZ01000009_gene942	0.0	1654.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,2TQK9@28211|Alphaproteobacteria,2K0VM@204457|Sphingomonadales	204457|Sphingomonadales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
CMS1_k127_4963712_5	1280950.HJO_08242	1.221e-57	209.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4
CMS1_k127_4963712_3	1044.EH31_01500	3.778e-70	254.0	COG3595@1|root,COG3595@2|Bacteria,1QUNK@1224|Proteobacteria,2TW1Z@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4963712_0	1174684.EBMC1_03135	0.0	1019.0	COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TS2Q@28211|Alphaproteobacteria,2K18E@204457|Sphingomonadales	204457|Sphingomonadales	CG	Dehydrogenase	-	-	1.1.9.1	ko:K17760	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrome_CBB3,PQQ,PQQ_2
CMS1_k127_4963712_4	1248760.ANFZ01000013_gene1865	1.263e-60	211.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2U73Z@28211|Alphaproteobacteria,2K4IQ@204457|Sphingomonadales	204457|Sphingomonadales	K	Belongs to the P(II) protein family	glnB	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
CMS1_k127_4963712_1	383381.EH30_01730	4.379e-278	857.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,2TSCR@28211|Alphaproteobacteria,2K06N@204457|Sphingomonadales	204457|Sphingomonadales	E	highly regulated protein controlled by the addition removal of adenylyl groups by adenylyltransferase from specific tyrosine residues	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
CMS1_k127_4963712_2	247634.GPB2148_496	3.29e-147	469.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RMQ4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
CMS1_k127_4998505_5	1545915.JROG01000003_gene1653	6.724e-73	247.0	COG1960@1|root,COG1960@2|Bacteria,1R3VD@1224|Proteobacteria,2U2WQ@28211|Alphaproteobacteria,2K8QW@204457|Sphingomonadales	204457|Sphingomonadales	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS1_k127_4998505_6	1545915.JROG01000003_gene1652	1.937e-64	226.0	COG1960@1|root,COG1960@2|Bacteria,1R7M8@1224|Proteobacteria,2TS45@28211|Alphaproteobacteria,2KCQD@204457|Sphingomonadales	204457|Sphingomonadales	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
CMS1_k127_4998505_4	1248760.ANFZ01000014_gene2098	4.644e-81	274.0	COG1960@1|root,COG1960@2|Bacteria,1R7M8@1224|Proteobacteria,2TS45@28211|Alphaproteobacteria,2KCQD@204457|Sphingomonadales	204457|Sphingomonadales	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
CMS1_k127_4998505_2	314225.ELI_00050	1.37e-105	349.0	COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,2TRIH@28211|Alphaproteobacteria,2K3C4@204457|Sphingomonadales	204457|Sphingomonadales	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS1_k127_4998505_1	314225.ELI_14995	1.011e-125	412.0	COG2267@1|root,COG2267@2|Bacteria,1R9GQ@1224|Proteobacteria,2U3YF@28211|Alphaproteobacteria,2K2J4@204457|Sphingomonadales	204457|Sphingomonadales	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
CMS1_k127_4998505_3	1279038.KB907338_gene941	3.962e-100	337.0	COG0388@1|root,COG0388@2|Bacteria,1MWQG@1224|Proteobacteria,2TYHX@28211|Alphaproteobacteria,2JSUU@204441|Rhodospirillales	204441|Rhodospirillales	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
CMS1_k127_4998505_7	1232683.ADIMK_1493	8.61e-15	83.0	COG1842@1|root,COG1842@2|Bacteria,1NB0D@1224|Proteobacteria,1RTFI@1236|Gammaproteobacteria,467CV@72275|Alteromonadaceae	1236|Gammaproteobacteria	KT	PspA/IM30 family	-	-	-	-	-	-	-	-	-	-	-	-	PspA_IM30
CMS1_k127_4998505_0	1280941.HY2_09860	5.976e-165	521.0	COG2070@1|root,COG2070@2|Bacteria,1MWPC@1224|Proteobacteria,2TQRT@28211|Alphaproteobacteria,43XYZ@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	COG2070 Dioxygenases related to 2-nitropropane dioxygenase	MA20_07330	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
CMS1_k127_502416_0	1248760.ANFZ01000002_gene3165	8.066e-246	767.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,2TQNY@28211|Alphaproteobacteria,2K15Q@204457|Sphingomonadales	204457|Sphingomonadales	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
CMS1_k127_502416_4	1207055.C100_04495	8.084e-45	169.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,2U9XK@28211|Alphaproteobacteria,2K4Y5@204457|Sphingomonadales	204457|Sphingomonadales	O	Peptidyl-prolyl cis-trans	-	-	5.2.1.8	ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
CMS1_k127_502416_3	1207055.C100_04495	3.845e-59	210.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,2U9XK@28211|Alphaproteobacteria,2K4Y5@204457|Sphingomonadales	204457|Sphingomonadales	O	Peptidyl-prolyl cis-trans	-	-	5.2.1.8	ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
CMS1_k127_502416_5	1248916.ANFY01000007_gene2424	2.381e-29	117.0	COG0828@1|root,COG0828@2|Bacteria,1MZA1@1224|Proteobacteria,2UC58@28211|Alphaproteobacteria,2K5X3@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
CMS1_k127_502416_1	1379701.JPJC01000006_gene372	9.405e-107	351.0	COG0235@1|root,COG0235@2|Bacteria,1MWP9@1224|Proteobacteria,2TRMV@28211|Alphaproteobacteria,2K1HY@204457|Sphingomonadales	204457|Sphingomonadales	G	Aldolase	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
CMS1_k127_502416_2	1174684.EBMC1_12986	1.171e-92	307.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,2TVRA@28211|Alphaproteobacteria,2K405@204457|Sphingomonadales	204457|Sphingomonadales	C	aerobic-type carbon monoxide dehydrogenase, small subunit CoxS	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
CMS1_k127_502416_6	1085623.GNIT_1340	6.582e-26	108.0	COG4774@1|root,COG4774@2|Bacteria,1MV0X@1224|Proteobacteria,1RN3C@1236|Gammaproteobacteria,46A0A@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	TonB dependent receptor	-	-	-	ko:K16090	-	-	-	-	ko00000,ko02000	1.B.14.1.11	-	-	Plug,TonB_dep_Rec
CMS1_k127_5035262_9	517722.AEUE01000004_gene866	1.817e-42	158.0	COG0745@1|root,COG0745@2|Bacteria,1RHCU@1224|Proteobacteria,2U98H@28211|Alphaproteobacteria,2K6Q8@204457|Sphingomonadales	204457|Sphingomonadales	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS1_k127_5035262_8	517722.AEUE01000004_gene867	7.158e-93	319.0	COG3063@1|root,COG3063@2|Bacteria,1N5QP@1224|Proteobacteria,2VD4Y@28211|Alphaproteobacteria,2KAW5@204457|Sphingomonadales	204457|Sphingomonadales	NU	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19
CMS1_k127_5035262_5	517722.AEUE01000004_gene868	8.823e-103	343.0	COG1413@1|root,COG1413@2|Bacteria,1N7UC@1224|Proteobacteria,2UGUW@28211|Alphaproteobacteria,2KAUU@204457|Sphingomonadales	204457|Sphingomonadales	C	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
CMS1_k127_5035262_1	517722.AEUE01000004_gene869	1.994e-226	709.0	COG1215@1|root,COG1215@2|Bacteria,1MXG7@1224|Proteobacteria,2TVZ5@28211|Alphaproteobacteria,2K1ER@204457|Sphingomonadales	204457|Sphingomonadales	GM	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
CMS1_k127_5035262_0	1112216.JH594425_gene1779	4.23e-301	967.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2U4KP@28211|Alphaproteobacteria,2K0WD@204457|Sphingomonadales	204457|Sphingomonadales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,MASE1,PAS,PAS_3,Response_reg
CMS1_k127_5035262_3	1449049.JONW01000009_gene4482	2.755e-194	614.0	2DBU1@1|root,2ZB3C@2|Bacteria,1NB4B@1224|Proteobacteria,2U0ZG@28211|Alphaproteobacteria,2KHJR@204458|Caulobacterales	204458|Caulobacterales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5035262_6	1122137.AQXF01000004_gene1662	3.405e-94	315.0	COG1802@1|root,COG1802@2|Bacteria,1N7GE@1224|Proteobacteria,2TRBH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Transcriptional regulator, gntR family	MA20_43175	-	-	ko:K11475	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
CMS1_k127_5035262_4	1122137.AQXF01000004_gene1663	5.895e-133	433.0	COG1680@1|root,COG1680@2|Bacteria,1PPFA@1224|Proteobacteria,2TV95@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS1_k127_5035262_7	450851.PHZ_c2016	2.789e-93	310.0	COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,1R6PS@1224|Proteobacteria,2TT0B@28211|Alphaproteobacteria,2KI8C@204458|Caulobacterales	204458|Caulobacterales	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS1_k127_5035262_2	1123073.KB899241_gene2159	7.694e-199	632.0	COG1680@1|root,COG1680@2|Bacteria,1PQ2Z@1224|Proteobacteria,1SYR1@1236|Gammaproteobacteria,1XCSI@135614|Xanthomonadales	135614|Xanthomonadales	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS1_k127_5041027_1	1123267.JONN01000001_gene977	5.916e-84	283.0	COG1738@1|root,COG1738@2|Bacteria,1RJV6@1224|Proteobacteria,2U7IX@28211|Alphaproteobacteria,2K2CH@204457|Sphingomonadales	204457|Sphingomonadales	S	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
CMS1_k127_5041027_2	1123267.JONN01000001_gene979	5.988e-70	243.0	COG1611@1|root,COG1611@2|Bacteria,1RD59@1224|Proteobacteria,2U5DP@28211|Alphaproteobacteria,2K0TW@204457|Sphingomonadales	204457|Sphingomonadales	K	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
CMS1_k127_5041027_0	1248760.ANFZ01000002_gene3075	4.274e-162	518.0	COG1972@1|root,COG1972@2|Bacteria,1MXXX@1224|Proteobacteria,2TU8A@28211|Alphaproteobacteria,2K07T@204457|Sphingomonadales	204457|Sphingomonadales	F	nucleoside	-	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
CMS1_k127_5057627_2	1123270.ATUR01000006_gene40	2.96e-49	181.0	COG0642@1|root,COG2205@2|Bacteria,1MVY8@1224|Proteobacteria,2TS5B@28211|Alphaproteobacteria,2K08R@204457|Sphingomonadales	204457|Sphingomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_7
CMS1_k127_5057627_1	291985.CCSI01000001_gene2464	9.267e-84	282.0	COG0521@1|root,COG0521@2|Bacteria,1R9W2@1224|Proteobacteria,2TTA8@28211|Alphaproteobacteria,2K0DJ@204457|Sphingomonadales	204457|Sphingomonadales	H	May be involved in the biosynthesis of molybdopterin	moaB	-	2.7.7.75	ko:K03638	ko00790,ko01100,map00790,map01100	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
CMS1_k127_5057627_0	685778.AORL01000021_gene364	1.613e-149	481.0	COG1533@1|root,COG1533@2|Bacteria,1MW0H@1224|Proteobacteria,2TQQB@28211|Alphaproteobacteria,2K118@204457|Sphingomonadales	204457|Sphingomonadales	L	DNA repair photolyase	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
CMS1_k127_5057627_3	317655.Sala_1180	5.432e-19	86.0	COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,2TR96@28211|Alphaproteobacteria,2K0TE@204457|Sphingomonadales	204457|Sphingomonadales	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	6.2.1.44	ko:K00666,ko:K20034	ko00920,map00920	-	R10820	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
CMS1_k127_5058344_1	1296990.H845_1914	2.953e-114	379.0	COG1887@1|root,COG1887@2|Bacteria,1R4MQ@1224|Proteobacteria,2U1UT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5058344_3	579138.Zymop_1119	3.591e-67	238.0	COG0746@1|root,COG0746@2|Bacteria,1QWF1@1224|Proteobacteria,2TXF5@28211|Alphaproteobacteria,2KEHV@204457|Sphingomonadales	204457|Sphingomonadales	H	MobA-like NTP transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3
CMS1_k127_5058344_0	1248760.ANFZ01000002_gene3223	6.393e-118	386.0	COG3118@1|root,COG3118@2|Bacteria,1MV0R@1224|Proteobacteria,2TS5X@28211|Alphaproteobacteria,2K0HB@204457|Sphingomonadales	204457|Sphingomonadales	O	Thioredoxin	-	-	-	ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	TPR_15,TPR_19,TPR_20,Thioredoxin
CMS1_k127_5058344_2	1248760.ANFZ01000002_gene3222	4.436e-86	297.0	COG2802@1|root,COG2802@2|Bacteria,1NV9N@1224|Proteobacteria,2TQZ4@28211|Alphaproteobacteria,2K0QK@204457|Sphingomonadales	204457|Sphingomonadales	S	to the N-terminal domain of Lon protease	-	-	-	ko:K07157	-	-	-	-	ko00000	-	-	-	LON_substr_bdg
CMS1_k127_5058344_5	648757.Rvan_0642	3.4e-17	82.0	COG2835@1|root,COG2835@2|Bacteria,1N6Y2@1224|Proteobacteria,2UF4N@28211|Alphaproteobacteria,3N9D1@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	Belongs to the UPF0434 family	MA20_24965	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Trm112p
CMS1_k127_5058344_6	509190.Cseg_0887	2.873e-11	72.0	COG2771@1|root,COG2771@2|Bacteria,1NAK1@1224|Proteobacteria,2U7AK@28211|Alphaproteobacteria,2KI55@204458|Caulobacterales	204458|Caulobacterales	K	Protein of unknown function (DUF4019)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4019,GerE
CMS1_k127_5058344_8	1120705.FG95_03421	3.847e-05	54.0	2DPV3@1|root,333H6@2|Bacteria,1NPG6@1224|Proteobacteria,2UKUP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5058344_4	1331060.RLDS_11970	2.839e-25	111.0	2EP5S@1|root,33GSG@2|Bacteria,1NI0K@1224|Proteobacteria,2UK2B@28211|Alphaproteobacteria,2K81U@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5062341_5	1545915.JROG01000004_gene1922	1.985e-112	371.0	COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,2TQV8@28211|Alphaproteobacteria,2K02I@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
CMS1_k127_5062341_2	1123270.ATUR01000004_gene1447	2.055e-184	582.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,2TS2T@28211|Alphaproteobacteria,2K0XB@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
CMS1_k127_5062341_6	1545915.JROG01000004_gene1692	1.052e-55	196.0	COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,2U756@28211|Alphaproteobacteria,2K4FX@204457|Sphingomonadales	204457|Sphingomonadales	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
CMS1_k127_5062341_7	1248760.ANFZ01000002_gene2975	9.082e-33	127.0	COG0291@1|root,COG0291@2|Bacteria,1N6V4@1224|Proteobacteria,2UF6K@28211|Alphaproteobacteria,2K5YR@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
CMS1_k127_5062341_4	161528.ED21_20084	6.532e-130	418.0	COG0483@1|root,COG0483@2|Bacteria,1PPJ0@1224|Proteobacteria,2TQTX@28211|Alphaproteobacteria,2K0WC@204457|Sphingomonadales	204457|Sphingomonadales	G	COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Inositol_P
CMS1_k127_5062341_3	314225.ELI_13790	1.916e-157	503.0	COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,2TR4Y@28211|Alphaproteobacteria,2K0MQ@204457|Sphingomonadales	204457|Sphingomonadales	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
CMS1_k127_5062341_0	1522072.IL54_4145	1.735e-273	850.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,2TRAU@28211|Alphaproteobacteria,2K0R3@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
CMS1_k127_5062341_1	1123269.NX02_28005	1.386e-201	637.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,2TRCI@28211|Alphaproteobacteria,2K0M4@204457|Sphingomonadales	204457|Sphingomonadales	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX2	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
CMS1_k127_5098827_1	158500.BV97_02114	1.069e-72	250.0	COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,2TQZW@28211|Alphaproteobacteria,2K0HT@204457|Sphingomonadales	204457|Sphingomonadales	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
CMS1_k127_5098827_3	237727.NAP1_12998	2.448e-20	96.0	2EMU4@1|root,33FGG@2|Bacteria,1NNB6@1224|Proteobacteria,2UMJV@28211|Alphaproteobacteria,2K6U1@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5098827_0	1122970.AUHC01000010_gene1622	1.28e-104	344.0	COG0412@1|root,COG0412@2|Bacteria,1MW88@1224|Proteobacteria,2U1D8@28211|Alphaproteobacteria,2K0IT@204457|Sphingomonadales	204457|Sphingomonadales	Q	dienelactone hydrolase	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
CMS1_k127_5098827_2	291985.CCSI01000002_gene1432	1.294e-44	167.0	COG3631@1|root,COG3631@2|Bacteria,1RHRD@1224|Proteobacteria,2U9AT@28211|Alphaproteobacteria,2K50G@204457|Sphingomonadales	204457|Sphingomonadales	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
CMS1_k127_5098827_4	1123270.ATUR01000004_gene1470	1.126e-13	71.0	COG0861@1|root,COG0861@2|Bacteria,1PN8B@1224|Proteobacteria,2TUV5@28211|Alphaproteobacteria,2K1SQ@204457|Sphingomonadales	204457|Sphingomonadales	P	membrane protein, TerC	-	-	-	-	-	-	-	-	-	-	-	-	TerC
CMS1_k127_5099941_1	1248760.ANFZ01000011_gene308	5.229e-75	259.0	COG3380@1|root,COG3380@2|Bacteria,1R5C0@1224|Proteobacteria,2U3PZ@28211|Alphaproteobacteria,2K1KZ@204457|Sphingomonadales	204457|Sphingomonadales	S	Flavin containing amine oxidoreductase	-	-	-	ko:K06955	-	-	-	-	ko00000	-	-	-	Amino_oxidase,NAD_binding_8
CMS1_k127_5099941_2	1550073.JROH01000001_gene703	5.621e-38	153.0	2AM63@1|root,31C0H@2|Bacteria,1N4E2@1224|Proteobacteria,2UEUX@28211|Alphaproteobacteria,2K6WN@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF3429)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3429
CMS1_k127_5099941_0	502025.Hoch_1681	9.706e-87	297.0	COG0451@1|root,COG0451@2|Bacteria,1P603@1224|Proteobacteria,42NGH@68525|delta/epsilon subdivisions,2WKS6@28221|Deltaproteobacteria,2YV7C@29|Myxococcales	28221|Deltaproteobacteria	M	RmlD substrate binding domain	-	-	1.1.1.394,1.1.1.412	ko:K21271,ko:K22320	-	-	-	-	ko00000,ko01000	-	-	-	3Beta_HSD
CMS1_k127_5121669_6	1123270.ATUR01000002_gene2049	1.677e-27	111.0	COG2041@1|root,COG2041@2|Bacteria,1MUW0@1224|Proteobacteria,2TS40@28211|Alphaproteobacteria,2K206@204457|Sphingomonadales	204457|Sphingomonadales	S	COG2041 Sulfite oxidase and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
CMS1_k127_5121669_1	1123269.NX02_26770	8.969e-178	566.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,2TR8K@28211|Alphaproteobacteria,2K0PR@204457|Sphingomonadales	204457|Sphingomonadales	M	synthase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
CMS1_k127_5121669_4	317655.Sala_0493	3.746e-49	182.0	2CHCP@1|root,32S5R@2|Bacteria,1MZ97@1224|Proteobacteria,2U9KI@28211|Alphaproteobacteria,2K5WE@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
CMS1_k127_5121669_0	1248760.ANFZ01000004_gene2031	1.411e-241	753.0	COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,2TTGS@28211|Alphaproteobacteria,2K0AN@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
CMS1_k127_5121669_2	1123270.ATUR01000002_gene2211	1.694e-100	336.0	COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,2TST5@28211|Alphaproteobacteria,2K5FS@204457|Sphingomonadales	204457|Sphingomonadales	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
CMS1_k127_5121669_3	1219049.SP5_053_00070	5.042e-67	233.0	COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,2TS4E@28211|Alphaproteobacteria,2K45N@204457|Sphingomonadales	204457|Sphingomonadales	S	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
CMS1_k127_5121669_5	1122612.AUBA01000005_gene2930	3.779e-42	156.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,2TRQN@28211|Alphaproteobacteria,2K1KF@204457|Sphingomonadales	204457|Sphingomonadales	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
CMS1_k127_5134387_10	551275.KB899544_gene1775	1.646e-34	140.0	COG3670@1|root,COG3670@2|Bacteria,1MY1X@1224|Proteobacteria,2TS7A@28211|Alphaproteobacteria,43Y7G@69657|Hyphomonadaceae	28211|Alphaproteobacteria	Q	COG3670 Lignostilbene-alpha,beta-dioxygenase and related enzymes	-	-	-	ko:K11159	-	-	-	-	ko00000	-	-	-	RPE65
CMS1_k127_5134387_3	1174684.EBMC1_06179	1.284e-134	434.0	COG2171@1|root,COG2171@2|Bacteria,1MU0Y@1224|Proteobacteria,2TS3H@28211|Alphaproteobacteria,2K055@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the transferase hexapeptide repeat family	dapD	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,THDPS_N_2
CMS1_k127_5134387_5	1346791.M529_02200	9.122e-79	272.0	COG1011@1|root,COG1011@2|Bacteria,1PHPQ@1224|Proteobacteria,2TUDN@28211|Alphaproteobacteria,2KEBI@204457|Sphingomonadales	204457|Sphingomonadales	S	Hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
CMS1_k127_5134387_0	1248760.ANFZ01000009_gene1502	0.0	1089.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,2TRDD@28211|Alphaproteobacteria,2K0XY@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
CMS1_k127_5134387_8	452662.SJA_C1-22850	6.289e-64	222.0	COG0735@1|root,COG0735@2|Bacteria,1MZIW@1224|Proteobacteria,2U9G4@28211|Alphaproteobacteria,2K4GM@204457|Sphingomonadales	204457|Sphingomonadales	P	Belongs to the Fur family	-	-	-	ko:K09823	ko02024,map02024	-	-	-	ko00000,ko00001,ko03000	-	-	-	FUR
CMS1_k127_5134387_9	1090320.KB900605_gene3654	1.896e-40	153.0	2EC1J@1|root,3360P@2|Bacteria,1NCAE@1224|Proteobacteria,2UMDW@28211|Alphaproteobacteria,2K72C@204457|Sphingomonadales	204457|Sphingomonadales	S	MerC mercury resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MerC
CMS1_k127_5134387_2	1346791.M529_04745	2.397e-151	485.0	COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,2TR0M@28211|Alphaproteobacteria,2K0QN@204457|Sphingomonadales	204457|Sphingomonadales	O	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
CMS1_k127_5134387_4	1123270.ATUR01000004_gene1711	7.209e-80	269.0	COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,2U5FM@28211|Alphaproteobacteria,2K28X@204457|Sphingomonadales	204457|Sphingomonadales	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
CMS1_k127_5134387_6	1219049.SP5_060_01080	1.022e-77	263.0	COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,2U5B5@28211|Alphaproteobacteria,2K0C7@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
CMS1_k127_5134387_7	745310.G432_02165	9.568e-73	262.0	COG2244@1|root,COG2244@2|Bacteria,1RDQG@1224|Proteobacteria,2U6PC@28211|Alphaproteobacteria,2K0Q9@204457|Sphingomonadales	204457|Sphingomonadales	S	Membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
CMS1_k127_5134387_1	1122135.KB893168_gene1951	1.077e-188	596.0	COG0498@1|root,COG0498@2|Bacteria,1R7X1@1224|Proteobacteria,2TUR3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Threonine synthase	MA20_41710	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS1_k127_5134387_11	1174684.EBMC1_04294	1.733e-14	76.0	COG0657@1|root,COG0657@2|Bacteria,1N2XW@1224|Proteobacteria,2U3QT@28211|Alphaproteobacteria,2K2SB@204457|Sphingomonadales	204457|Sphingomonadales	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,COesterase
CMS1_k127_5199273_2	1192759.AKIB01000031_gene1191	3.117e-52	186.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,2TS7S@28211|Alphaproteobacteria,2JZWE@204457|Sphingomonadales	204457|Sphingomonadales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
CMS1_k127_5199273_1	314225.ELI_12100	3.235e-183	594.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS1_k127_5199273_3	1174684.EBMC1_00830	3.636e-51	188.0	COG1309@1|root,COG1309@2|Bacteria,1MUUY@1224|Proteobacteria,2TUIH@28211|Alphaproteobacteria,2K6PB@204457|Sphingomonadales	204457|Sphingomonadales	K	WHG domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
CMS1_k127_5199273_0	247634.GPB2148_2355	2.123e-232	726.0	COG3670@1|root,COG3670@2|Bacteria,1MY1X@1224|Proteobacteria,1RRE0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG3670 Lignostilbene-alpha,beta-dioxygenase and related enzymes	-	-	1.13.11.82	ko:K21822	-	-	-	-	ko00000,ko01000	-	-	-	RPE65
CMS1_k127_5235837_2	1120792.JAFV01000001_gene1980	1.25e-45	178.0	COG0457@1|root,COG1629@1|root,COG3712@1|root,COG0457@2|Bacteria,COG3712@2|Bacteria,COG4771@2|Bacteria,1RJUD@1224|Proteobacteria,2U2AY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	PT	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR,TPR_16,TPR_19,TPR_8
CMS1_k127_5235837_0	1185652.USDA257_c15860	3.609e-176	570.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,2U6VS@28211|Alphaproteobacteria,4BM30@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylate cyclase	cyaK	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
CMS1_k127_5235837_1	1408418.JNJH01000002_gene2849	4.187e-71	244.0	COG0702@1|root,COG0702@2|Bacteria,1REY2@1224|Proteobacteria,2TS22@28211|Alphaproteobacteria,2JV76@204441|Rhodospirillales	204441|Rhodospirillales	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
CMS1_k127_5246493_1	1248760.ANFZ01000009_gene1107	2.368e-228	720.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,2TRC1@28211|Alphaproteobacteria,2K0KI@204457|Sphingomonadales	204457|Sphingomonadales	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	RNB,S1
CMS1_k127_5246493_0	1470591.BW41_00225	2.151e-244	763.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,2TQQ4@28211|Alphaproteobacteria,2K1F1@204457|Sphingomonadales	204457|Sphingomonadales	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b
CMS1_k127_5246493_2	46429.BV95_00743	1.423e-59	213.0	COG5394@1|root,COG5394@2|Bacteria,1RHRC@1224|Proteobacteria,2TQWQ@28211|Alphaproteobacteria,2K0W5@204457|Sphingomonadales	204457|Sphingomonadales	S	synthesis repressor PhaR	phaR	-	-	-	-	-	-	-	-	-	-	-	PHB_acc,PHB_acc_N
CMS1_k127_5246493_3	314266.SKA58_09171	1.216e-30	122.0	COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,2TQKD@28211|Alphaproteobacteria,2K0BU@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
CMS1_k127_5259637_2	629773.AORY01000012_gene1026	3.413e-56	199.0	COG2860@1|root,COG2860@2|Bacteria,1RHQN@1224|Proteobacteria,2U6ZM@28211|Alphaproteobacteria,2K16N@204457|Sphingomonadales	204457|Sphingomonadales	S	UPF0126 domain	-	-	-	-	-	-	-	-	-	-	-	-	UPF0126
CMS1_k127_5259637_0	1545915.JROG01000003_gene1017	5.852e-203	650.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,2TSXA@28211|Alphaproteobacteria,2K1TY@204457|Sphingomonadales	204457|Sphingomonadales	OU	signal peptide peptidase	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
CMS1_k127_5259637_3	1248760.ANFZ01000009_gene1216	6.36e-49	182.0	COG4944@1|root,COG4944@2|Bacteria,1N3C7@1224|Proteobacteria,2VGWG@28211|Alphaproteobacteria,2K5Z0@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF1109)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1109
CMS1_k127_5259637_1	237727.NAP1_10873	4.285e-61	216.0	COG1595@1|root,COG1595@2|Bacteria,1MVS7@1224|Proteobacteria,2U5A2@28211|Alphaproteobacteria,2KC9U@204457|Sphingomonadales	204457|Sphingomonadales	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_5259637_4	317655.Sala_2679	3.355e-42	159.0	COG2259@1|root,COG2259@2|Bacteria,1N1VA@1224|Proteobacteria,2TVZ9@28211|Alphaproteobacteria,2K5X8@204457|Sphingomonadales	204457|Sphingomonadales	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
CMS1_k127_5284900_5	1545915.JROG01000004_gene2470	1.118e-166	529.0	COG0506@1|root,COG4230@1|root,COG0506@2|Bacteria,COG4230@2|Bacteria,1MV93@1224|Proteobacteria,2TQPT@28211|Alphaproteobacteria,2K1B6@204457|Sphingomonadales	204457|Sphingomonadales	CE	Oxidizes proline to glutamate for use as a carbon and nitrogen source	putA	-	1.2.1.88,1.5.5.2	ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh,Pro_dh-DNA_bdg
CMS1_k127_5284900_1	1174684.EBMC1_06074	2.268e-237	747.0	COG0069@1|root,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,2TREH@28211|Alphaproteobacteria,2K14G@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the glutamate synthase family	-	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase
CMS1_k127_5284900_10	1219049.SP5_016_00450	1.343e-60	212.0	COG1522@1|root,COG1522@2|Bacteria,1RCEQ@1224|Proteobacteria,2U6I5@28211|Alphaproteobacteria,2K497@204457|Sphingomonadales	204457|Sphingomonadales	K	transcriptional	-	-	-	ko:K05800	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24
CMS1_k127_5284900_9	1207055.C100_10665	2.075e-100	340.0	COG0334@1|root,COG0334@2|Bacteria,1MUXS@1224|Proteobacteria,2VGKD@28211|Alphaproteobacteria,2K0AY@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.9	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	-	R01088,R01434,R02196	RC00006,RC00036	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
CMS1_k127_5284900_4	1123073.KB899241_gene2164	2.514e-169	542.0	COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,1RQGU@1236|Gammaproteobacteria,1X5U5@135614|Xanthomonadales	135614|Xanthomonadales	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
CMS1_k127_5284900_2	1144305.PMI02_02321	2.695e-231	727.0	COG1680@1|root,COG1680@2|Bacteria,1MVZN@1224|Proteobacteria,2VF7X@28211|Alphaproteobacteria,2KDW0@204457|Sphingomonadales	204457|Sphingomonadales	V	Beta-lactamase class C	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
CMS1_k127_5284900_8	1174684.EBMC1_15202	1.392e-127	420.0	COG3949@1|root,COG3949@2|Bacteria,1QAYU@1224|Proteobacteria,2U6DV@28211|Alphaproteobacteria,2K0X7@204457|Sphingomonadales	204457|Sphingomonadales	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5284900_6	1502850.FG91_00618	1.022e-147	475.0	COG3367@1|root,COG3367@2|Bacteria,1MVEX@1224|Proteobacteria,2TS0Y@28211|Alphaproteobacteria,2K06Y@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF1611_N) Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1611,DUF1611_N
CMS1_k127_5284900_0	1112216.JH594426_gene3818	1.779e-304	952.0	COG1629@1|root,COG4771@2|Bacteria,1MVFB@1224|Proteobacteria,2U2KS@28211|Alphaproteobacteria,2KDKA@204457|Sphingomonadales	204457|Sphingomonadales	P	TonB-dependent receptor plug	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
CMS1_k127_5284900_3	517722.AEUE01000003_gene1270	1.774e-183	584.0	COG3104@1|root,COG3104@2|Bacteria,1MW6W@1224|Proteobacteria,2U15C@28211|Alphaproteobacteria,2K2WX@204457|Sphingomonadales	204457|Sphingomonadales	E	amino acid peptide transporter	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
CMS1_k127_5284900_7	1502850.FG91_00623	1.765e-136	445.0	COG4948@1|root,COG4948@2|Bacteria,1MW76@1224|Proteobacteria,2TR16@28211|Alphaproteobacteria,2K34I@204457|Sphingomonadales	204457|Sphingomonadales	M	Mandelate racemase muconate lactonizing enzyme	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
CMS1_k127_5284900_11	1090319.KE386571_gene1554	4.474e-44	166.0	COG1680@1|root,COG1680@2|Bacteria,1PQ2Z@1224|Proteobacteria,2U1GN@28211|Alphaproteobacteria,2K210@204457|Sphingomonadales	204457|Sphingomonadales	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS1_k127_5330817_7	279238.Saro_1975	5.714e-117	378.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,2TRFK@28211|Alphaproteobacteria,2K02S@204457|Sphingomonadales	204457|Sphingomonadales	C	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit	bkdA2	-	1.2.4.4	ko:K00167	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
CMS1_k127_5330817_1	1545915.JROG01000003_gene780	1.066e-211	664.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,2TSEI@28211|Alphaproteobacteria,2K13V@204457|Sphingomonadales	204457|Sphingomonadales	C	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit	bkdA1	-	1.2.4.4	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,OxoDH_E1alpha_N
CMS1_k127_5330817_4	1144307.PMI04_04182	3.509e-169	535.0	COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,2TQSB@28211|Alphaproteobacteria,2K0PF@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
CMS1_k127_5330817_0	1174684.EBMC1_15177	6.601e-289	900.0	COG1680@1|root,COG1680@2|Bacteria,1PQ2Z@1224|Proteobacteria,2U1GN@28211|Alphaproteobacteria,2K210@204457|Sphingomonadales	204457|Sphingomonadales	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS1_k127_5330817_5	631454.N177_2809	2.116e-153	510.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria,1JPNG@119043|Rhodobiaceae	28211|Alphaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Response_reg
CMS1_k127_5330817_2	1123270.ATUR01000003_gene799	2.117e-186	612.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2TRHH@28211|Alphaproteobacteria,2K2UP@204457|Sphingomonadales	204457|Sphingomonadales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,Response_reg,TPR_12
CMS1_k127_5330817_6	1123270.ATUR01000003_gene800	1.465e-122	400.0	COG1024@1|root,COG1024@2|Bacteria,1MUD7@1224|Proteobacteria,2U230@28211|Alphaproteobacteria,2K2FV@204457|Sphingomonadales	204457|Sphingomonadales	I	enoyl-CoA hydratase	-	-	-	ko:K13816	ko02020,ko02024,map02020,map02024	-	-	-	ko00000,ko00001	-	-	-	ECH_1
CMS1_k127_5330817_3	1174684.EBMC1_00465	1.285e-172	546.0	COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,2TT75@28211|Alphaproteobacteria,2K0GB@204457|Sphingomonadales	204457|Sphingomonadales	I	Glycerol-3-phosphate dehydrogenase	gpsA2	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
CMS1_k127_5330817_8	317655.Sala_0198	1.766e-61	216.0	COG0596@1|root,COG0596@2|Bacteria,1QVQ5@1224|Proteobacteria,2UEVX@28211|Alphaproteobacteria,2KCXE@204457|Sphingomonadales	204457|Sphingomonadales	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CMS1_k127_5332420_0	1502850.FG91_03537	0.0	1460.0	COG1629@1|root,COG4773@1|root,COG1629@2|Bacteria,COG4773@2|Bacteria,1R479@1224|Proteobacteria,2TV3V@28211|Alphaproteobacteria,2K147@204457|Sphingomonadales	204457|Sphingomonadales	P	COG1629 Outer membrane receptor proteins, mostly Fe transport	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
CMS1_k127_5332420_1	314225.ELI_09015	0.0	1278.0	COG1629@1|root,COG4774@1|root,COG1629@2|Bacteria,COG4774@2|Bacteria,1NMCN@1224|Proteobacteria,2TW2G@28211|Alphaproteobacteria,2KE9A@204457|Sphingomonadales	204457|Sphingomonadales	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
CMS1_k127_5332420_20	1037409.BJ6T_14340	5.582e-11	63.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,3JUGV@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Resolvase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
CMS1_k127_5332420_14	1123269.NX02_13365	6.377e-86	291.0	COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,2UAW0@28211|Alphaproteobacteria,2K2UB@204457|Sphingomonadales	204457|Sphingomonadales	NOU	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	gspO	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
CMS1_k127_5332420_6	1248917.ANFX01000031_gene2560	2.834e-180	573.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2TQQ7@28211|Alphaproteobacteria,2K0FQ@204457|Sphingomonadales	204457|Sphingomonadales	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
CMS1_k127_5332420_16	1123270.ATUR01000005_gene525	3.342e-51	185.0	COG3807@1|root,COG3807@2|Bacteria,1RHM2@1224|Proteobacteria,2UA1R@28211|Alphaproteobacteria,2K42W@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	SH3_4
CMS1_k127_5332420_9	1545915.JROG01000003_gene1512	3.018e-151	484.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,2TSM8@28211|Alphaproteobacteria,2K0RX@204457|Sphingomonadales	204457|Sphingomonadales	CH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	-	-	1.1.1.26	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	-	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
CMS1_k127_5332420_5	314225.ELI_06725	3.261e-194	614.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,2TT2J@28211|Alphaproteobacteria,2K3DE@204457|Sphingomonadales	204457|Sphingomonadales	P	Ammonium Transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
CMS1_k127_5332420_15	450851.PHZ_c0633	6.752e-58	204.0	COG0454@1|root,COG0456@2|Bacteria,1RHB3@1224|Proteobacteria,2U70A@28211|Alphaproteobacteria,2KGYE@204458|Caulobacterales	204458|Caulobacterales	K	Acetyltransferase (GNAT) domain	-	-	-	ko:K03829	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
CMS1_k127_5332420_3	1545915.JROG01000004_gene2306	6.209e-266	822.0	COG2070@1|root,COG2070@2|Bacteria,1N52W@1224|Proteobacteria,2TV8B@28211|Alphaproteobacteria,2K00A@204457|Sphingomonadales	204457|Sphingomonadales	S	2-nitropropane dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
CMS1_k127_5332420_8	1248760.ANFZ01000003_gene1653	1.055e-154	497.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,2U43G@28211|Alphaproteobacteria,2K0KR@204457|Sphingomonadales	204457|Sphingomonadales	M	Glycosyl transferase family 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS1_k127_5332420_13	1112214.AHIS01000033_gene1108	8.765e-89	312.0	COG0596@1|root,COG0596@2|Bacteria,1MVVX@1224|Proteobacteria,2TT0S@28211|Alphaproteobacteria,2K14Q@204457|Sphingomonadales	204457|Sphingomonadales	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS1_k127_5332420_7	1123270.ATUR01000005_gene531	1.171e-179	576.0	COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,2TT84@28211|Alphaproteobacteria,2JZUT@204457|Sphingomonadales	204457|Sphingomonadales	S	Uncharacterized ACR, YdiU/UPF0061 family	-	-	-	-	-	-	-	-	-	-	-	-	UPF0061
CMS1_k127_5332420_4	46429.BV95_02940	7.975e-217	681.0	COG1012@1|root,COG1012@2|Bacteria,1MV2I@1224|Proteobacteria,2TU8S@28211|Alphaproteobacteria,2K13M@204457|Sphingomonadales	204457|Sphingomonadales	C	Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate	astD	-	1.2.1.71	ko:K06447	ko00330,ko01100,map00330,map01100	-	R05049	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
CMS1_k127_5332420_11	1114964.L485_19390	1.426e-109	361.0	COG0007@1|root,COG0007@2|Bacteria,1MUI0@1224|Proteobacteria,2TRJC@28211|Alphaproteobacteria,2K1SG@204457|Sphingomonadales	204457|Sphingomonadales	H	Belongs to the precorrin methyltransferase family	cysG	-	2.1.1.107	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03194	RC00003,RC00871	ko00000,ko00001,ko00002,ko01000	-	-	-	TP_methylase
CMS1_k127_5332420_17	317655.Sala_0771	2.204e-48	176.0	2EG12@1|root,339T3@2|Bacteria,1NGID@1224|Proteobacteria,2UK0A@28211|Alphaproteobacteria,2K5XT@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF2849)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2849
CMS1_k127_5332420_2	1123270.ATUR01000005_gene536	2.095e-306	944.0	COG0155@1|root,COG0155@2|Bacteria,1MVVB@1224|Proteobacteria,2TRCR@28211|Alphaproteobacteria,2K14A@204457|Sphingomonadales	204457|Sphingomonadales	C	Sulfite reductase	cysI	-	1.8.1.2	ko:K00381	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00858	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
CMS1_k127_5332420_18	1479239.JQMU01000001_gene2316	4.971e-44	165.0	COG3749@1|root,COG3749@2|Bacteria,1RJR9@1224|Proteobacteria,2UA02@28211|Alphaproteobacteria,2K4PM@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF934
CMS1_k127_5332420_10	1346791.M529_10600	1.662e-128	417.0	COG0175@1|root,COG0175@2|Bacteria,1MXUR@1224|Proteobacteria,2U5AP@28211|Alphaproteobacteria,2K0FD@204457|Sphingomonadales	204457|Sphingomonadales	EH	Reduction of activated sulfate into sulfite	cysH	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
CMS1_k127_5332420_12	1123270.ATUR01000008_gene255	8.784e-109	357.0	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,2TSF9@28211|Alphaproteobacteria,2K1TQ@204457|Sphingomonadales	204457|Sphingomonadales	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
CMS1_k127_5386846_3	1545915.JROG01000003_gene1045	1.92e-182	577.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,2TT63@28211|Alphaproteobacteria,2K09I@204457|Sphingomonadales	204457|Sphingomonadales	H	Involved in the biosynthesis of porphyrin-containing compound	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
CMS1_k127_5386846_8	1207055.C100_15940	7.503e-126	409.0	COG4974@1|root,COG4974@2|Bacteria,1QU6A@1224|Proteobacteria,2TS7W@28211|Alphaproteobacteria,2K1R3@204457|Sphingomonadales	204457|Sphingomonadales	L	Belongs to the 'phage' integrase family	xerC_2	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
CMS1_k127_5386846_17	745310.G432_02970	1.658e-58	215.0	COG0589@1|root,COG0589@2|Bacteria,1Q3J7@1224|Proteobacteria,2UAE7@28211|Alphaproteobacteria,2K4N4@204457|Sphingomonadales	204457|Sphingomonadales	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS1_k127_5386846_14	1248760.ANFZ01000009_gene1246	9.466e-67	233.0	COG0586@1|root,COG0586@2|Bacteria,1MX4M@1224|Proteobacteria,2U6ZF@28211|Alphaproteobacteria,2K1Q0@204457|Sphingomonadales	204457|Sphingomonadales	S	membrane-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
CMS1_k127_5386846_4	1219035.NT2_06_00240	4.364e-163	517.0	COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,2TQNE@28211|Alphaproteobacteria,2K0JQ@204457|Sphingomonadales	204457|Sphingomonadales	H	Belongs to the prokaryotic GSH synthase family	gshB	-	6.3.2.3	ko:K01920	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00497,R10994	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	GSH-S_ATP,GSH-S_N
CMS1_k127_5386846_20	1545915.JROG01000003_gene1049	3.484e-35	143.0	COG0792@1|root,COG0792@2|Bacteria,1N6VN@1224|Proteobacteria,2UFTM@28211|Alphaproteobacteria,2K62R@204457|Sphingomonadales	204457|Sphingomonadales	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
CMS1_k127_5386846_12	1550073.JROH01000023_gene827	6.52e-100	333.0	COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,2TR14@28211|Alphaproteobacteria,2K0AW@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
CMS1_k127_5386846_7	1123270.ATUR01000003_gene827	5.76e-140	457.0	COG0683@1|root,COG0683@2|Bacteria,1QURG@1224|Proteobacteria,2TS62@28211|Alphaproteobacteria,2K08C@204457|Sphingomonadales	204457|Sphingomonadales	E	Extracellular ligand-binding receptor	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
CMS1_k127_5386846_10	1545915.JROG01000003_gene1052	1.158e-123	399.0	COG0176@1|root,COG0176@2|Bacteria,1MWQ8@1224|Proteobacteria,2TQJB@28211|Alphaproteobacteria,2K0F2@204457|Sphingomonadales	204457|Sphingomonadales	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
CMS1_k127_5386846_22	1096930.L284_06570	2.798e-19	96.0	2DN4B@1|root,32VFQ@2|Bacteria,1REFD@1224|Proteobacteria,2U8MH@28211|Alphaproteobacteria,2KE43@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF2490)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2490
CMS1_k127_5386846_16	1123270.ATUR01000003_gene938	9.369e-60	214.0	29BA9@1|root,2ZY8N@2|Bacteria,1RJEZ@1224|Proteobacteria,2U9H3@28211|Alphaproteobacteria,2K4P7@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF4197)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4197
CMS1_k127_5386846_0	745310.G432_04895	0.0	1035.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,2TQTQ@28211|Alphaproteobacteria,2K0DV@204457|Sphingomonadales	204457|Sphingomonadales	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C
CMS1_k127_5386846_5	1123270.ATUR01000002_gene2494	1.982e-157	512.0	COG0265@1|root,COG0265@2|Bacteria,1R5U1@1224|Proteobacteria,2U2NR@28211|Alphaproteobacteria,2KDBM@204457|Sphingomonadales	204457|Sphingomonadales	O	Trypsin-like serine protease	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
CMS1_k127_5386846_11	1174684.EBMC1_08170	3.076e-101	344.0	COG2513@1|root,COG2513@2|Bacteria,1R3SD@1224|Proteobacteria,2U3CR@28211|Alphaproteobacteria,2K4EU@204457|Sphingomonadales	204457|Sphingomonadales	G	COG2513 PEP phosphonomutase and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	PEP_mutase
CMS1_k127_5386846_6	314225.ELI_08745	3.35e-143	461.0	COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,1N2YQ@1224|Proteobacteria,2TQRX@28211|Alphaproteobacteria,2K165@204457|Sphingomonadales	204457|Sphingomonadales	FL	Metal binding domain of Ada	ada	-	2.1.1.63	ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1,HTH_18,Methyltransf_1N
CMS1_k127_5386846_18	1120705.FG95_03007	6.077e-48	177.0	2CVTP@1|root,32SY9@2|Bacteria,1N209@1224|Proteobacteria,2UC8J@28211|Alphaproteobacteria,2K5PS@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF1203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1203
CMS1_k127_5386846_15	194867.ALBQ01000014_gene414	1.648e-64	228.0	COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,2U5IC@28211|Alphaproteobacteria,2K4UU@204457|Sphingomonadales	204457|Sphingomonadales	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
CMS1_k127_5386846_1	314266.SKA58_06540	1.798e-291	899.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,2TQYK@28211|Alphaproteobacteria,2K08A@204457|Sphingomonadales	204457|Sphingomonadales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
CMS1_k127_5386846_9	1088721.NSU_4138	2.54e-124	404.0	COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,2TR11@28211|Alphaproteobacteria,2K0A5@204457|Sphingomonadales	204457|Sphingomonadales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
CMS1_k127_5386846_2	392499.Swit_0623	3.04e-280	865.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,2TRGP@28211|Alphaproteobacteria,2K03H@204457|Sphingomonadales	204457|Sphingomonadales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
CMS1_k127_5386846_21	1549858.MC45_10245	1.293e-32	128.0	COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,2UBXX@28211|Alphaproteobacteria,2K5WN@204457|Sphingomonadales	204457|Sphingomonadales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02113,ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE_N
CMS1_k127_5386846_13	13689.BV96_03051	3.348e-69	248.0	COG0438@1|root,COG0438@2|Bacteria,1NSQQ@1224|Proteobacteria,2UQTA@28211|Alphaproteobacteria,2KCSP@204457|Sphingomonadales	204457|Sphingomonadales	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CMS1_k127_5386846_19	237727.NAP1_01715	3.475e-44	168.0	COG0697@1|root,COG0697@2|Bacteria,1RAJV@1224|Proteobacteria,2U5BF@28211|Alphaproteobacteria,2K3YW@204457|Sphingomonadales	204457|Sphingomonadales	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS1_k127_5388849_2	1007104.SUS17_206	2.355e-34	132.0	COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,2TSDP@28211|Alphaproteobacteria,2K010@204457|Sphingomonadales	204457|Sphingomonadales	L	Belongs to the DNA photolyase family	-	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
CMS1_k127_5388849_0	392499.Swit_0580	3.64e-162	520.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,2TR8K@28211|Alphaproteobacteria,2K1IB@204457|Sphingomonadales	204457|Sphingomonadales	M	synthase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
CMS1_k127_5388849_1	1120705.FG95_01951	4.412e-145	471.0	COG1680@1|root,COG1680@2|Bacteria,1P3SQ@1224|Proteobacteria,2TTI5@28211|Alphaproteobacteria,2K1R1@204457|Sphingomonadales	204457|Sphingomonadales	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS1_k127_5388849_3	1112214.AHIS01000095_gene859	1.984e-15	76.0	COG0300@1|root,COG0300@2|Bacteria,1QUNR@1224|Proteobacteria,2TW24@28211|Alphaproteobacteria,2K1AC@204457|Sphingomonadales	204457|Sphingomonadales	S	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS1_k127_5390881_2	745310.G432_17295	2.394e-59	207.0	COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,2TR5I@28211|Alphaproteobacteria,2K1GJ@204457|Sphingomonadales	204457|Sphingomonadales	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
CMS1_k127_5390881_0	1479239.JQMU01000001_gene688	3.692e-108	355.0	COG1028@1|root,COG1028@2|Bacteria,1MURZ@1224|Proteobacteria,2TQJ6@28211|Alphaproteobacteria,2K2RN@204457|Sphingomonadales	204457|Sphingomonadales	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	ko:K18335	ko00051,ko01120,map00051,map01120	-	R10690	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
CMS1_k127_5390881_1	383381.EH30_15725	8.576e-78	261.0	COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,2TSJ5@28211|Alphaproteobacteria,2K0FW@204457|Sphingomonadales	204457|Sphingomonadales	P	Ring hydroxylating alpha subunit (catalytic domain)	-	-	-	-	-	-	-	-	-	-	-	-	Rieske,Ring_hydroxyl_A
CMS1_k127_539780_5	1449076.JOOE01000003_gene3685	8.484e-69	235.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,2TR60@28211|Alphaproteobacteria,2K1XQ@204457|Sphingomonadales	204457|Sphingomonadales	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
CMS1_k127_539780_9	1380391.JIAS01000012_gene3919	1.493e-17	94.0	COG2207@1|root,COG2207@2|Bacteria,1MX23@1224|Proteobacteria,2TT6H@28211|Alphaproteobacteria,2JRG2@204441|Rhodospirillales	204441|Rhodospirillales	K	Arabinose-binding domain of AraC transcription regulator, N-term	-	-	-	-	-	-	-	-	-	-	-	-	Arabinose_bd,HTH_18
CMS1_k127_539780_6	1123270.ATUR01000004_gene1638	1.705e-55	196.0	COG2204@1|root,COG2204@2|Bacteria,1RD1D@1224|Proteobacteria,2U76U@28211|Alphaproteobacteria,2KE99@204457|Sphingomonadales	204457|Sphingomonadales	T	cheY-homologous receiver domain	-	-	-	ko:K13589	ko02020,ko04112,map02020,map04112	M00512	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
CMS1_k127_539780_4	1123270.ATUR01000004_gene1637	1.172e-80	278.0	COG3741@1|root,COG3741@2|Bacteria,1MY4D@1224|Proteobacteria,2TUPZ@28211|Alphaproteobacteria,2K41R@204457|Sphingomonadales	204457|Sphingomonadales	E	N-formylglutamate amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FGase
CMS1_k127_539780_2	1123270.ATUR01000004_gene1635	9.61e-121	392.0	COG1262@1|root,COG1262@2|Bacteria,1Q227@1224|Proteobacteria,2U2IQ@28211|Alphaproteobacteria,2K0P1@204457|Sphingomonadales	204457|Sphingomonadales	S	SapC	-	-	-	-	-	-	-	-	-	-	-	-	SapC
CMS1_k127_539780_1	1545915.JROG01000003_gene1134	3.817e-197	626.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2TRYI@28211|Alphaproteobacteria,2K0VP@204457|Sphingomonadales	204457|Sphingomonadales	C	FAD linked	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4
CMS1_k127_539780_7	1545915.JROG01000003_gene1133	5.468e-33	133.0	2AM8F@1|root,31C39@2|Bacteria,1N008@1224|Proteobacteria,2UCNF@28211|Alphaproteobacteria,2K748@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_539780_0	745310.G432_16870	4.291e-199	631.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2TR6Q@28211|Alphaproteobacteria,2K0CY@204457|Sphingomonadales	204457|Sphingomonadales	L	Belongs to the DEAD box helicase family	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
CMS1_k127_539780_8	13690.CP98_00844	8.635e-28	120.0	2AA6W@1|root,30ZFY@2|Bacteria,1NT2P@1224|Proteobacteria,2UQFS@28211|Alphaproteobacteria,2K8GX@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_539780_3	1123270.ATUR01000002_gene2424	3.896e-82	276.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria,2K0T8@204457|Sphingomonadales	204457|Sphingomonadales	T	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS1_k127_5404485_6	1123270.ATUR01000002_gene2639	1.266e-99	331.0	COG0702@1|root,COG0702@2|Bacteria,1RCCP@1224|Proteobacteria,2TU1D@28211|Alphaproteobacteria,2K0TF@204457|Sphingomonadales	204457|Sphingomonadales	GM	epimerase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
CMS1_k127_5404485_8	1030157.AFMP01000044_gene1819	3.358e-41	163.0	COG1418@1|root,COG1418@2|Bacteria,1RGE5@1224|Proteobacteria,2U8QJ@28211|Alphaproteobacteria,2K54J@204457|Sphingomonadales	204457|Sphingomonadales	S	mRNA catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5404485_9	745310.G432_04450	2.869e-31	127.0	COG0236@1|root,COG0236@2|Bacteria,1NHQD@1224|Proteobacteria,2UGSG@28211|Alphaproteobacteria,2K5YB@204457|Sphingomonadales	204457|Sphingomonadales	IQ	acyl carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
CMS1_k127_5404485_0	1502850.FG91_01928	1.708e-231	719.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,2TQYP@28211|Alphaproteobacteria,2K0V8@204457|Sphingomonadales	204457|Sphingomonadales	E	COG0156 7-keto-8-aminopelargonate synthetase and related enzymes	-	-	2.3.1.29,2.3.1.47	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	M00123,M00573,M00577	R00371,R03210,R10124	RC00004,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS1_k127_5404485_5	1044.EH31_06205	9.509e-109	367.0	COG1024@1|root,COG1024@2|Bacteria,1MXHV@1224|Proteobacteria,2TTEG@28211|Alphaproteobacteria,2K2N5@204457|Sphingomonadales	204457|Sphingomonadales	I	enoyl-CoA hydratase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS1_k127_5404485_4	1207055.C100_01100	8.65e-113	371.0	COG3153@1|root,COG3153@2|Bacteria,1QURI@1224|Proteobacteria,2TSFI@28211|Alphaproteobacteria,2KEAP@204457|Sphingomonadales	204457|Sphingomonadales	S	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5404485_3	1123269.NX02_17790	3.364e-133	431.0	COG1597@1|root,COG1597@2|Bacteria,1R78V@1224|Proteobacteria,2U0V0@28211|Alphaproteobacteria,2K03G@204457|Sphingomonadales	204457|Sphingomonadales	I	Diacylglycerol kinase	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
CMS1_k127_5404485_7	317655.Sala_2175	2.69e-55	198.0	COG4704@1|root,COG4704@2|Bacteria,1REQD@1224|Proteobacteria,2U8UI@28211|Alphaproteobacteria,2K510@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2141
CMS1_k127_5404485_1	1545915.JROG01000004_gene1788	6.323e-199	625.0	COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,2U55Q@28211|Alphaproteobacteria,2K07C@204457|Sphingomonadales	204457|Sphingomonadales	S	YjgP YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
CMS1_k127_5404485_2	1550073.JROH01000009_gene1313	2.199e-148	477.0	COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,2TR76@28211|Alphaproteobacteria,2K1ZM@204457|Sphingomonadales	204457|Sphingomonadales	S	YjgP YjgQ family	-	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
CMS1_k127_5419570_10	1030157.AFMP01000013_gene3343	8.167e-94	315.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2TQP0@28211|Alphaproteobacteria,2K1VP@204457|Sphingomonadales	204457|Sphingomonadales	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K02032,ko:K13896	ko02010,ko02024,map02010,map02024	M00239,M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.21,3.A.1.5.24	-	-	ABC_tran,oligo_HPY
CMS1_k127_5419570_7	1123269.NX02_26720	7.896e-117	388.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,2TTEV@28211|Alphaproteobacteria,2K2QZ@204457|Sphingomonadales	204457|Sphingomonadales	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
CMS1_k127_5419570_3	745310.G432_09795	8.785e-133	429.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TTN3@28211|Alphaproteobacteria,2K2XV@204457|Sphingomonadales	204457|Sphingomonadales	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
CMS1_k127_5419570_2	1123320.KB889562_gene6749	8.308e-149	479.0	COG0596@1|root,COG0596@2|Bacteria,2GK79@201174|Actinobacteria	201174|Actinobacteria	K	epoxide hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	EHN
CMS1_k127_5419570_5	745310.G432_08900	8.999e-130	419.0	COG1250@1|root,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2TR8E@28211|Alphaproteobacteria,2K0X2@204457|Sphingomonadales	204457|Sphingomonadales	I	Dehydrogenase	paaH	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
CMS1_k127_5419570_12	1335760.ASTG01000018_gene3333	3.307e-63	230.0	COG5342@1|root,COG5342@2|Bacteria,1MXZW@1224|Proteobacteria,2UD3E@28211|Alphaproteobacteria,2K3Y1@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF1176)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1176
CMS1_k127_5419570_4	1248760.ANFZ01000004_gene1928	7.164e-131	427.0	COG4301@1|root,COG4301@2|Bacteria,1MUCG@1224|Proteobacteria,2TRMH@28211|Alphaproteobacteria,2K0WW@204457|Sphingomonadales	204457|Sphingomonadales	S	Histidine-specific methyltransferase, SAM-dependent	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_33
CMS1_k127_5419570_1	1144307.PMI04_02885	1.799e-178	567.0	COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria,2TQXE@28211|Alphaproteobacteria,2K0TI@204457|Sphingomonadales	204457|Sphingomonadales	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase
CMS1_k127_5419570_11	627192.SLG_06140	6.108e-74	253.0	COG2096@1|root,COG2096@2|Bacteria,1RDUF@1224|Proteobacteria,2U5J1@28211|Alphaproteobacteria,2K3VX@204457|Sphingomonadales	204457|Sphingomonadales	S	adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
CMS1_k127_5419570_9	1096930.L284_05175	8.849e-106	351.0	COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,2TR2V@28211|Alphaproteobacteria,2K0FZ@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	gluQ	-	-	ko:K01894	-	-	-	-	ko00000,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c
CMS1_k127_5419570_8	452662.SJA_C1-07960	5.938e-114	368.0	COG1403@1|root,COG1403@2|Bacteria,1MWEQ@1224|Proteobacteria,2TR3M@28211|Alphaproteobacteria,2K04Q@204457|Sphingomonadales	204457|Sphingomonadales	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
CMS1_k127_5419570_0	1280953.HOC_06478	4.55e-259	809.0	COG0457@1|root,COG0457@2|Bacteria,1N0A9@1224|Proteobacteria,2TTMN@28211|Alphaproteobacteria,43XB8@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_2,TPR_8
CMS1_k127_5419570_6	1545915.JROG01000007_gene3258	3.957e-117	382.0	COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,2TR6F@28211|Alphaproteobacteria,2K1W8@204457|Sphingomonadales	204457|Sphingomonadales	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
CMS1_k127_5438766_12	1280947.HY30_00645	5.998e-67	233.0	COG1670@1|root,COG1670@2|Bacteria,1MZAM@1224|Proteobacteria,2US5F@28211|Alphaproteobacteria,43YE2@69657|Hyphomonadaceae	28211|Alphaproteobacteria	J	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
CMS1_k127_5438766_4	670307.HYPDE_25983	1.466e-154	517.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria,3N7R3@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,MASE1,PAS_4,PAS_7,PAS_8
CMS1_k127_5438766_0	1248760.ANFZ01000018_gene684	4.06e-211	676.0	COG2072@1|root,COG2072@2|Bacteria,1MU71@1224|Proteobacteria,2TV2E@28211|Alphaproteobacteria,2JZVQ@204457|Sphingomonadales	204457|Sphingomonadales	P	Flavin-binding monooxygenase-like	-	-	-	-	-	-	-	-	-	-	-	-	FMO-like,NAD_binding_8,Pyr_redox_3
CMS1_k127_5438766_14	1449076.JOOE01000001_gene2937	1.566e-24	106.0	2BSQ5@1|root,32MSZ@2|Bacteria,1PPID@1224|Proteobacteria,2V202@28211|Alphaproteobacteria,2KB27@204457|Sphingomonadales	204457|Sphingomonadales	S	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
CMS1_k127_5438766_1	1112214.AHIS01000086_gene434	4.636e-200	634.0	COG2072@1|root,COG2072@2|Bacteria,1MU71@1224|Proteobacteria,2TV2E@28211|Alphaproteobacteria,2JZVQ@204457|Sphingomonadales	204457|Sphingomonadales	P	Flavin-binding monooxygenase-like	-	-	-	-	-	-	-	-	-	-	-	-	FMO-like,NAD_binding_8,Pyr_redox_3
CMS1_k127_5438766_3	13690.CP98_01209	5.035e-179	572.0	COG0260@1|root,COG0260@2|Bacteria,1MUIN@1224|Proteobacteria,2TSI6@28211|Alphaproteobacteria,2JZV7@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the peptidase M17 family	-	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17
CMS1_k127_5438766_8	1174684.EBMC1_05179	1.984e-118	391.0	COG2885@1|root,COG2885@2|Bacteria,1R5IS@1224|Proteobacteria,2U2V8@28211|Alphaproteobacteria,2K1H8@204457|Sphingomonadales	204457|Sphingomonadales	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
CMS1_k127_5438766_10	1248760.ANFZ01000018_gene687	6.669e-97	327.0	COG0791@1|root,COG0791@2|Bacteria,1MW03@1224|Proteobacteria,2TSFG@28211|Alphaproteobacteria,2K27W@204457|Sphingomonadales	204457|Sphingomonadales	M	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60
CMS1_k127_5438766_6	517722.AEUE01000004_gene773	4.15e-122	399.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,2TRMT@28211|Alphaproteobacteria,2K2G3@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh
CMS1_k127_5438766_9	627192.SLG_08320	5.238e-112	369.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,2TR9N@28211|Alphaproteobacteria,2K1V9@204457|Sphingomonadales	204457|Sphingomonadales	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
CMS1_k127_5438766_13	702113.PP1Y_AT4730	1.653e-66	231.0	COG0736@1|root,COG0736@2|Bacteria,1MZBF@1224|Proteobacteria,2U77S@28211|Alphaproteobacteria,2K4ID@204457|Sphingomonadales	204457|Sphingomonadales	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
CMS1_k127_5438766_7	1030157.AFMP01000040_gene1410	2.377e-121	394.0	COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,2TTTF@28211|Alphaproteobacteria,2K0T4@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	-	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
CMS1_k127_5438766_11	1123269.NX02_27365	6.627e-88	293.0	COG0461@1|root,COG0461@2|Bacteria,1RIC5@1224|Proteobacteria,2TUX2@28211|Alphaproteobacteria,2K1QD@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
CMS1_k127_5438766_5	1248760.ANFZ01000021_gene358	2.928e-126	413.0	COG1622@1|root,COG1622@2|Bacteria,1MWHZ@1224|Proteobacteria,2TRK6@28211|Alphaproteobacteria,2K00C@204457|Sphingomonadales	204457|Sphingomonadales	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	ctaC	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM
CMS1_k127_5438766_2	1207055.C100_04535	2.031e-188	593.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,2TQP1@28211|Alphaproteobacteria,2K034@204457|Sphingomonadales	204457|Sphingomonadales	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	ctaD	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
CMS1_k127_5443890_3	1248760.ANFZ01000002_gene3169	1.185e-34	140.0	COG3595@1|root,COG3595@2|Bacteria,1N374@1224|Proteobacteria,2U8XP@28211|Alphaproteobacteria,2KCHG@204457|Sphingomonadales	204457|Sphingomonadales	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
CMS1_k127_5443890_1	1248760.ANFZ01000023_gene142	2.588e-92	305.0	COG1329@1|root,COG1329@2|Bacteria,1MWI2@1224|Proteobacteria,2TTVP@28211|Alphaproteobacteria,2K0TA@204457|Sphingomonadales	204457|Sphingomonadales	K	CarD family transcriptional regulator	-	-	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
CMS1_k127_5443890_2	1248760.ANFZ01000023_gene141	4.339e-65	223.0	COG1146@1|root,COG1146@2|Bacteria,1RH5I@1224|Proteobacteria,2U98K@28211|Alphaproteobacteria,2K4E8@204457|Sphingomonadales	204457|Sphingomonadales	C	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions	-	-	-	ko:K05524	-	-	-	-	ko00000	-	-	-	DUF3470,Fer4,Fer4_4
CMS1_k127_5443890_4	1219045.BV98_000245	2.844e-26	110.0	COG1188@1|root,COG1188@2|Bacteria,1MZR6@1224|Proteobacteria,2UBS3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)	hslR	-	-	ko:K04762	-	-	-	-	ko00000,ko03110	-	-	-	S4
CMS1_k127_5443890_0	1123270.ATUR01000002_gene2271	5.673e-297	937.0	COG4581@1|root,COG4581@2|Bacteria,1MVD6@1224|Proteobacteria,2TR7N@28211|Alphaproteobacteria,2JZXM@204457|Sphingomonadales	204457|Sphingomonadales	L	helicase	-	-	3.6.4.13	ko:K17675	-	-	-	-	ko00000,ko01000,ko03029	-	-	-	Helicase_C
CMS1_k127_5443890_5	1120705.FG95_01425	1.224e-12	72.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2TT3Z@28211|Alphaproteobacteria,2K2A0@204457|Sphingomonadales	204457|Sphingomonadales	M	membrane	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CMS1_k127_5455133_4	1123269.NX02_26775	2.333e-66	233.0	COG2041@1|root,COG2041@2|Bacteria,1MUW0@1224|Proteobacteria,2TS40@28211|Alphaproteobacteria,2K206@204457|Sphingomonadales	204457|Sphingomonadales	S	COG2041 Sulfite oxidase and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
CMS1_k127_5455133_2	1502850.FG91_01081	7.613e-109	358.0	COG4117@1|root,COG4117@2|Bacteria,1MX97@1224|Proteobacteria,2U0ZF@28211|Alphaproteobacteria,2K0DE@204457|Sphingomonadales	204457|Sphingomonadales	C	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
CMS1_k127_5455133_5	1346791.M529_04655	2.81e-52	190.0	COG3637@1|root,COG3637@2|Bacteria,1NJWW@1224|Proteobacteria,2UD8G@28211|Alphaproteobacteria,2K4HB@204457|Sphingomonadales	204457|Sphingomonadales	M	Outer membrane protein beta-barrel domain	-	-	-	ko:K16079	-	-	-	-	ko00000,ko02000	1.B.4.2.1	-	-	OMP_b-brl
CMS1_k127_5455133_6	1248760.ANFZ01000002_gene2954	1.479e-49	180.0	COG0251@1|root,COG0251@2|Bacteria,1REJQ@1224|Proteobacteria,2U70D@28211|Alphaproteobacteria,2K5HA@204457|Sphingomonadales	204457|Sphingomonadales	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
CMS1_k127_5455133_0	452662.SJA_C1-09080	7.881e-223	696.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,2TQT3@28211|Alphaproteobacteria,2K0CT@204457|Sphingomonadales	204457|Sphingomonadales	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
CMS1_k127_5455133_7	1545915.JROG01000003_gene1279	9.969e-48	179.0	COG5342@1|root,COG5342@2|Bacteria,1NVB8@1224|Proteobacteria,2UAQU@28211|Alphaproteobacteria,2K5Q9@204457|Sphingomonadales	204457|Sphingomonadales	S	invasion associated locus B	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5455133_3	1030157.AFMP01000016_gene2363	5.264e-67	235.0	COG0406@1|root,COG0406@2|Bacteria,1RG9K@1224|Proteobacteria,2U8NV@28211|Alphaproteobacteria,2K1EM@204457|Sphingomonadales	204457|Sphingomonadales	G	Histidine phosphatase superfamily (branch 1)	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
CMS1_k127_5455133_1	1123270.ATUR01000004_gene1647	5.984e-183	577.0	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,2TSRZ@28211|Alphaproteobacteria,2K052@204457|Sphingomonadales	204457|Sphingomonadales	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
CMS1_k127_5474705_8	1545915.JROG01000004_gene1862	1.037e-100	333.0	COG1902@1|root,COG1902@2|Bacteria,1MVIX@1224|Proteobacteria,2TT2F@28211|Alphaproteobacteria,2K0I7@204457|Sphingomonadales	204457|Sphingomonadales	C	NADH flavin	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
CMS1_k127_5474705_13	1123270.ATUR01000008_gene269	1.118e-29	125.0	COG5317@1|root,COG5317@2|Bacteria,1N9DI@1224|Proteobacteria,2UFAD@28211|Alphaproteobacteria,2KDEZ@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF1465)	-	-	-	ko:K13592	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	DUF1465
CMS1_k127_5474705_14	383381.EH30_00570	2.902e-19	88.0	COG5481@1|root,COG5481@2|Bacteria,1NG9U@1224|Proteobacteria,2UFXJ@28211|Alphaproteobacteria,2K6XC@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF465)	-	-	-	-	-	-	-	-	-	-	-	-	DUF465
CMS1_k127_5474705_16	570967.JMLV01000020_gene411	4.239e-07	52.0	COG5570@1|root,COG5570@2|Bacteria,1NGRE@1224|Proteobacteria,2UJAX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Small protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF465
CMS1_k127_5474705_0	1545915.JROG01000003_gene726	0.0	1078.0	COG3605@1|root,COG3605@2|Bacteria,1QTTV@1224|Proteobacteria,2TR3Z@28211|Alphaproteobacteria,2K17Q@204457|Sphingomonadales	204457|Sphingomonadales	T	Belongs to the PEP-utilizing enzyme family	ptsP	-	2.7.3.9	ko:K08484	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	GAF_2,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
CMS1_k127_5474705_11	627192.SLG_23570	6.791e-62	222.0	COG1426@1|root,COG1426@2|Bacteria,1MYWX@1224|Proteobacteria,2U8C2@28211|Alphaproteobacteria,2K4QD@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF4115)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4115,HTH_25
CMS1_k127_5474705_10	1545915.JROG01000003_gene728	6.43e-82	285.0	COG1729@1|root,COG1729@2|Bacteria,1R8C4@1224|Proteobacteria,2VBNQ@28211|Alphaproteobacteria,2K0FK@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TolA_bind_tri
CMS1_k127_5474705_9	1335760.ASTG01000001_gene3171	1.734e-82	284.0	COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,2TRK1@28211|Alphaproteobacteria,2K3YA@204457|Sphingomonadales	204457|Sphingomonadales	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3
CMS1_k127_5474705_1	13689.BV96_01361	0.0	1066.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,2TSYQ@28211|Alphaproteobacteria,2K1U5@204457|Sphingomonadales	204457|Sphingomonadales	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
CMS1_k127_5474705_12	1346791.M529_19100	4.368e-52	186.0	COG1758@1|root,COG1758@2|Bacteria,1N6TX@1224|Proteobacteria,2U9BQ@28211|Alphaproteobacteria,2K5I6@204457|Sphingomonadales	204457|Sphingomonadales	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
CMS1_k127_5474705_6	1335760.ASTG01000024_gene2315	5.485e-117	391.0	COG1502@1|root,COG1502@2|Bacteria,1R8FQ@1224|Proteobacteria,2TVT6@28211|Alphaproteobacteria,2KE81@204457|Sphingomonadales	204457|Sphingomonadales	I	Phospholipase D Active site motif	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
CMS1_k127_5474705_5	1123270.ATUR01000007_gene1315	1.479e-135	441.0	COG2367@1|root,COG2367@2|Bacteria,1PNSR@1224|Proteobacteria,2U483@28211|Alphaproteobacteria,2K1SY@204457|Sphingomonadales	204457|Sphingomonadales	V	beta-lactamase	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2,Peptidase_S13
CMS1_k127_5474705_15	314225.ELI_12020	2.891e-14	75.0	2A8ZE@1|root,30Y39@2|Bacteria,1P5JS@1224|Proteobacteria,2UX96@28211|Alphaproteobacteria,2KBJA@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5474705_17	1120705.FG95_00793	2.515e-06	53.0	2AMHZ@1|root,31CDK@2|Bacteria,1NPD4@1224|Proteobacteria,2UJRC@28211|Alphaproteobacteria,2K85P@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5474705_7	1335760.ASTG01000005_gene1056	4.687e-103	345.0	COG0500@1|root,COG0640@1|root,COG0640@2|Bacteria,COG2226@2|Bacteria,1NFSV@1224|Proteobacteria,2TSMV@28211|Alphaproteobacteria,2K0VB@204457|Sphingomonadales	204457|Sphingomonadales	K	ArsR family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5,Methyltransf_11
CMS1_k127_5474705_4	1123270.ATUR01000007_gene1311	6.883e-158	504.0	COG0685@1|root,COG0685@2|Bacteria,1MUC9@1224|Proteobacteria,2TQZA@28211|Alphaproteobacteria,2K03Q@204457|Sphingomonadales	204457|Sphingomonadales	E	Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
CMS1_k127_5474705_3	1123270.ATUR01000007_gene1310	4.228e-171	548.0	COG0646@1|root,COG0646@2|Bacteria,1NPFY@1224|Proteobacteria,2UJRS@28211|Alphaproteobacteria,2K10F@204457|Sphingomonadales	204457|Sphingomonadales	E	Methionine synthase I (cobalamin-dependent), methyltransferase domain	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	S-methyl_trans
CMS1_k127_5474705_2	1550073.JROH01000027_gene963	1.102e-220	689.0	COG1410@1|root,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,2TQTG@28211|Alphaproteobacteria,2K0JK@204457|Sphingomonadales	204457|Sphingomonadales	E	5-methyltetrahydrofolate--homocysteine methyltransferase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind
CMS1_k127_5485175_5	1123278.KB893387_gene4311	5.187e-138	452.0	COG0624@1|root,COG0624@2|Bacteria,4NEA7@976|Bacteroidetes,47JSS@768503|Cytophagia	976|Bacteroidetes	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
CMS1_k127_5485175_19	1248760.ANFZ01000014_gene2129	0.0001278	45.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,2TRRH@28211|Alphaproteobacteria,2K0SH@204457|Sphingomonadales	204457|Sphingomonadales	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
CMS1_k127_5485175_0	279238.Saro_1421	1.883e-282	885.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria,2K07A@204457|Sphingomonadales	204457|Sphingomonadales	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4,PAS_9,PilZ
CMS1_k127_5485175_7	2074.JNYD01000026_gene709	2.47e-128	413.0	COG1024@1|root,COG1024@2|Bacteria,2GN69@201174|Actinobacteria,4E5AI@85010|Pseudonocardiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS1_k127_5485175_1	383381.EH30_15685	7.626e-238	747.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,2K1MV@204457|Sphingomonadales	204457|Sphingomonadales	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
CMS1_k127_5485175_15	1122197.ATWI01000012_gene685	1.766e-42	166.0	COG1082@1|root,COG1082@2|Bacteria,1R3UQ@1224|Proteobacteria,1S3NU@1236|Gammaproteobacteria,46BD2@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS1_k127_5485175_17	1030157.AFMP01000007_gene3157	2.14e-28	120.0	COG5517@1|root,COG5517@2|Bacteria,1NN6V@1224|Proteobacteria,2VAW8@28211|Alphaproteobacteria,2K7S6@204457|Sphingomonadales	204457|Sphingomonadales	Q	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
CMS1_k127_5485175_2	1174684.EBMC1_07340	1.052e-163	525.0	COG1680@1|root,COG1680@2|Bacteria,1MY01@1224|Proteobacteria,2U91R@28211|Alphaproteobacteria,2KD3W@204457|Sphingomonadales	204457|Sphingomonadales	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS1_k127_5485175_8	1335760.ASTG01000002_gene2208	4.519e-123	396.0	COG2057@1|root,COG2057@2|Bacteria,1RA4V@1224|Proteobacteria,2TQS5@28211|Alphaproteobacteria,2JZXA@204457|Sphingomonadales	204457|Sphingomonadales	I	Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit	scoB	-	2.8.3.5	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	-	R00410	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
CMS1_k127_5485175_16	314225.ELI_14305	3.506e-36	149.0	29W6C@1|root,30HRF@2|Bacteria,1NJUD@1224|Proteobacteria,2UM17@28211|Alphaproteobacteria,2K7G6@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5485175_6	1248760.ANFZ01000004_gene1940	1.509e-132	426.0	COG1788@1|root,COG1788@2|Bacteria,1MVEI@1224|Proteobacteria,2TTE6@28211|Alphaproteobacteria,2K0EF@204457|Sphingomonadales	204457|Sphingomonadales	I	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit	scoA	-	2.8.3.5	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	-	R00410	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
CMS1_k127_5485175_11	1248760.ANFZ01000009_gene1429	7.89e-84	290.0	COG4246@1|root,COG4246@2|Bacteria,1N7Y1@1224|Proteobacteria,2TTZW@28211|Alphaproteobacteria,2K10G@204457|Sphingomonadales	204457|Sphingomonadales	S	Esterase-like activity of phytase	-	-	-	-	-	-	-	-	-	-	-	-	Phytase-like
CMS1_k127_5485175_14	392499.Swit_2326	5.887e-43	160.0	COG0227@1|root,COG0227@2|Bacteria,1MZ57@1224|Proteobacteria,2UBQU@28211|Alphaproteobacteria,2K561@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
CMS1_k127_5485175_13	237727.NAP1_13348	3.719e-55	196.0	COG0590@1|root,COG0590@2|Bacteria,1RGU0@1224|Proteobacteria,2U77Q@28211|Alphaproteobacteria,2K4E6@204457|Sphingomonadales	204457|Sphingomonadales	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
CMS1_k127_5485175_4	1537715.JQFJ01000002_gene1878	1.829e-141	452.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,2TSPC@28211|Alphaproteobacteria,2K1DU@204457|Sphingomonadales	204457|Sphingomonadales	T	Response regulator of the LytR AlgR family	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
CMS1_k127_5485175_3	1248760.ANFZ01000009_gene1425	1.297e-156	505.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,2U16F@28211|Alphaproteobacteria,2JZWJ@204457|Sphingomonadales	204457|Sphingomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
CMS1_k127_5485175_10	1112214.AHIS01000065_gene2663	3.973e-92	306.0	COG4341@1|root,COG4341@2|Bacteria,1QHQD@1224|Proteobacteria,2U0VM@28211|Alphaproteobacteria,2KD8G@204457|Sphingomonadales	204457|Sphingomonadales	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
CMS1_k127_5485175_12	1248760.ANFZ01000002_gene3167	1.217e-67	234.0	COG1733@1|root,COG1733@2|Bacteria,1RIZT@1224|Proteobacteria,2U7SS@28211|Alphaproteobacteria,2K4MD@204457|Sphingomonadales	204457|Sphingomonadales	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
CMS1_k127_5485175_18	517722.AEUE01000002_gene2391	6.831e-18	88.0	2EG1C@1|root,302SI@2|Bacteria,1PVTE@1224|Proteobacteria,2V71Z@28211|Alphaproteobacteria,2K8BP@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5485175_9	1219035.NT2_08_01340	5.397e-106	346.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,2TQNY@28211|Alphaproteobacteria,2K15Q@204457|Sphingomonadales	204457|Sphingomonadales	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5,3.1.7.2	ko:K00951,ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
CMS1_k127_5507858_7	383381.EH30_11780	4.548e-60	211.0	COG4774@1|root,COG4774@2|Bacteria,1NMCN@1224|Proteobacteria,2U1C8@28211|Alphaproteobacteria,2K263@204457|Sphingomonadales	204457|Sphingomonadales	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
CMS1_k127_5507858_6	1123267.JONN01000001_gene986	2.029e-65	232.0	COG3631@1|root,COG3631@2|Bacteria,1RH51@1224|Proteobacteria,2UA2P@28211|Alphaproteobacteria,2K4MH@204457|Sphingomonadales	204457|Sphingomonadales	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
CMS1_k127_5507858_4	1248760.ANFZ01000018_gene514	1.302e-82	275.0	COG3631@1|root,COG3631@2|Bacteria,1NQQJ@1224|Proteobacteria,2UP8A@28211|Alphaproteobacteria,2K3XV@204457|Sphingomonadales	204457|Sphingomonadales	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
CMS1_k127_5507858_3	1123267.JONN01000001_gene988	3.427e-137	438.0	COG4126@1|root,COG4126@2|Bacteria,1MVNB@1224|Proteobacteria,2TQQI@28211|Alphaproteobacteria,2K2HR@204457|Sphingomonadales	204457|Sphingomonadales	E	Hydantoin racemase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5507858_5	1248760.ANFZ01000018_gene516	9.137e-77	264.0	COG1802@1|root,COG1802@2|Bacteria,1N1X3@1224|Proteobacteria,2U5PS@28211|Alphaproteobacteria,2K3ZQ@204457|Sphingomonadales	204457|Sphingomonadales	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
CMS1_k127_5507858_0	383381.EH30_11805	1.623e-218	682.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TR7Q@28211|Alphaproteobacteria,2K0PV@204457|Sphingomonadales	204457|Sphingomonadales	C	dehydratase	-	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
CMS1_k127_5507858_2	383381.EH30_11810	6.85e-140	456.0	COG0119@1|root,COG0119@2|Bacteria,1MUMX@1224|Proteobacteria,2TT1R@28211|Alphaproteobacteria,2K1YI@204457|Sphingomonadales	204457|Sphingomonadales	E	HMGL-like	-	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
CMS1_k127_5507858_1	1248916.ANFY01000007_gene2156	5.526e-184	581.0	COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,2TQZ6@28211|Alphaproteobacteria,2K20D@204457|Sphingomonadales	204457|Sphingomonadales	EQ	PFAM Hydantoinase oxoprolinase	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
CMS1_k127_5512907_9	279238.Saro_0125	4.66e-11	65.0	COG3595@1|root,COG3595@2|Bacteria,1N374@1224|Proteobacteria,2U8XP@28211|Alphaproteobacteria,2KCHG@204457|Sphingomonadales	204457|Sphingomonadales	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
CMS1_k127_5512907_6	1545915.JROG01000009_gene2818	4.556e-86	289.0	COG0500@1|root,COG2226@2|Bacteria,1RANW@1224|Proteobacteria,2U66N@28211|Alphaproteobacteria,2K411@204457|Sphingomonadales	204457|Sphingomonadales	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
CMS1_k127_5512907_7	452662.SJA_C1-20940	3.677e-27	121.0	2DR57@1|root,33A7H@2|Bacteria,1Q5GH@1224|Proteobacteria,2UQ0P@28211|Alphaproteobacteria,2KCHF@204457|Sphingomonadales	204457|Sphingomonadales	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
CMS1_k127_5512907_8	1114964.L485_01420	9.582e-22	95.0	2A2WA@1|root,30RAD@2|Bacteria,1NY8N@1224|Proteobacteria,2USY9@28211|Alphaproteobacteria,2K6VV@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5512907_10	13689.BV96_03166	2.326e-07	55.0	2ARGG@1|root,31GSP@2|Bacteria,1P9MD@1224|Proteobacteria,2UYV9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5512907_2	1123270.ATUR01000008_gene278	4.705e-185	589.0	COG2133@1|root,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,2TRN9@28211|Alphaproteobacteria,2K068@204457|Sphingomonadales	204457|Sphingomonadales	G	sorbosone	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
CMS1_k127_5512907_3	13690.CP98_01201	2.123e-103	345.0	COG2607@1|root,COG2607@2|Bacteria,1MVMX@1224|Proteobacteria,2TTFE@28211|Alphaproteobacteria,2K28Z@204457|Sphingomonadales	204457|Sphingomonadales	P	ATPase (AAA superfamily)	-	-	-	ko:K06923	-	-	-	-	ko00000	-	-	-	DUF815
CMS1_k127_5512907_1	1248760.ANFZ01000002_gene3070	3.136e-240	756.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,2TQJS@28211|Alphaproteobacteria,2JZXJ@204457|Sphingomonadales	204457|Sphingomonadales	I	acyl-CoA dehydrogenase	-	-	-	ko:K20035	ko00920,map00920	-	R11130	RC03363	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
CMS1_k127_5512907_4	555793.WSK_0263	3.443e-102	341.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,2TRIM@28211|Alphaproteobacteria,2K1JS@204457|Sphingomonadales	204457|Sphingomonadales	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
CMS1_k127_5512907_5	1545915.JROG01000009_gene2635	4.537e-90	308.0	COG0845@1|root,COG0845@2|Bacteria,1NJDF@1224|Proteobacteria,2TSZA@28211|Alphaproteobacteria,2K42V@204457|Sphingomonadales	204457|Sphingomonadales	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3,HlyD_D23
CMS1_k127_5512907_0	1545915.JROG01000009_gene2634	0.0	1189.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria,2KCZ7@204457|Sphingomonadales	204457|Sphingomonadales	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
CMS1_k127_5533825_11	1122970.AUHC01000001_gene454	1.943e-16	79.0	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,2TQKJ@28211|Alphaproteobacteria,2K16M@204457|Sphingomonadales	204457|Sphingomonadales	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
CMS1_k127_5533825_0	1545915.JROG01000003_gene1656	0.0	1525.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,2TR3C@28211|Alphaproteobacteria,2K0KY@204457|Sphingomonadales	204457|Sphingomonadales	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
CMS1_k127_5533825_12	1087481.AGFX01000013_gene3067	1.587e-05	49.0	2BKI8@1|root,32EZF@2|Bacteria,1TZNM@1239|Firmicutes,4I8XU@91061|Bacilli,270PJ@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5533825_3	279238.Saro_2007	3.035e-109	355.0	COG0302@1|root,COG0302@2|Bacteria,1MY3N@1224|Proteobacteria,2TSZI@28211|Alphaproteobacteria,2K0QV@204457|Sphingomonadales	204457|Sphingomonadales	H	GTP cyclohydrolase	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
CMS1_k127_5533825_4	1502850.FG91_03539	1.961e-90	303.0	COG3128@1|root,COG3128@2|Bacteria,1MUI7@1224|Proteobacteria,2TRH2@28211|Alphaproteobacteria,2K99V@204457|Sphingomonadales	204457|Sphingomonadales	C	Prolyl 4-hydroxylase alpha subunit homologues.	-	-	-	ko:K07336	-	-	-	-	ko00000,ko01000	-	-	-	2OG-FeII_Oxy_3
CMS1_k127_5533825_7	745310.G432_04905	8.516e-76	267.0	2DWG9@1|root,34073@2|Bacteria,1NVA6@1224|Proteobacteria,2URJH@28211|Alphaproteobacteria,2K8JR@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5533825_8	1120705.FG95_01105	1.091e-70	245.0	COG0359@1|root,COG0359@2|Bacteria,1RD0R@1224|Proteobacteria,2TSC9@28211|Alphaproteobacteria,2K0UT@204457|Sphingomonadales	204457|Sphingomonadales	J	Binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
CMS1_k127_5533825_10	983920.Y88_3746	2.029e-34	132.0	COG0238@1|root,COG0238@2|Bacteria,1MZ8U@1224|Proteobacteria,2UC13@28211|Alphaproteobacteria,2K5WV@204457|Sphingomonadales	204457|Sphingomonadales	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
CMS1_k127_5533825_9	383381.EH30_07245	1.737e-52	187.0	COG0360@1|root,COG0360@2|Bacteria,1RH82@1224|Proteobacteria,2U767@28211|Alphaproteobacteria,2K4F9@204457|Sphingomonadales	204457|Sphingomonadales	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
CMS1_k127_5533825_1	1174684.EBMC1_03320	6.596e-310	965.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria,2K07A@204457|Sphingomonadales	204457|Sphingomonadales	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_4,PAS_9,PilZ
CMS1_k127_5533825_6	517722.AEUE01000008_gene9	2.918e-85	292.0	COG1462@1|root,COG1462@2|Bacteria,1RARC@1224|Proteobacteria,2U6YT@28211|Alphaproteobacteria,2K443@204457|Sphingomonadales	204457|Sphingomonadales	M	curli production assembly transport component CsgG	-	-	-	-	-	-	-	-	-	-	-	-	CsgG
CMS1_k127_5533825_2	1174684.EBMC1_11905	4.484e-119	393.0	COG2771@1|root,COG2771@2|Bacteria,1R5JB@1224|Proteobacteria,2U1CA@28211|Alphaproteobacteria,2KAF2@204457|Sphingomonadales	204457|Sphingomonadales	K	Protein involved in two-component response regulator activity and two-component signal transduction system (phosphorelay)	-	-	-	-	-	-	-	-	-	-	-	-	GerE
CMS1_k127_5533825_5	1207058.L53_15335	1.014e-87	291.0	COG1960@1|root,COG1960@2|Bacteria,1MWUU@1224|Proteobacteria,2TT47@28211|Alphaproteobacteria,43Z8U@69657|Hyphomonadaceae	28211|Alphaproteobacteria	I	Acyl-CoA dehydrogenase	MA20_16360	-	1.3.8.1,1.3.8.7	ko:K00248,ko:K00249	ko00071,ko00280,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01178,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00120,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS1_k127_5536342_9	1169161.KB897721_gene4186	3.038e-56	205.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria	201174|Actinobacteria	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
CMS1_k127_5536342_1	1545915.JROG01000001_gene467	3.309e-236	737.0	COG1473@1|root,COG1473@2|Bacteria,1MX6N@1224|Proteobacteria,2TRSE@28211|Alphaproteobacteria,2KDGW@204457|Sphingomonadales	204457|Sphingomonadales	S	amidohydrolase	-	-	-	ko:K12941	-	-	-	-	ko00000,ko01002	-	-	-	M20_dimer,Peptidase_M20
CMS1_k127_5536342_17	1545915.JROG01000009_gene2669	6.845e-14	74.0	2AM94@1|root,31C3Y@2|Bacteria,1NZI2@1224|Proteobacteria,2UTMT@28211|Alphaproteobacteria,2K8E3@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5536342_13	1545915.JROG01000008_gene3311	2.617e-33	140.0	COG0746@1|root,COG0746@2|Bacteria,1NBGZ@1224|Proteobacteria	1224|Proteobacteria	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
CMS1_k127_5536342_8	1248760.ANFZ01000014_gene2119	1.484e-58	210.0	COG3942@1|root,COG3942@2|Bacteria,1N0K8@1224|Proteobacteria,2UDGN@28211|Alphaproteobacteria,2K5G2@204457|Sphingomonadales	204457|Sphingomonadales	S	CHAP domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAP
CMS1_k127_5536342_3	745310.G432_11610	4.687e-121	398.0	COG1195@1|root,COG1195@2|Bacteria,1MX8N@1224|Proteobacteria,2TQRD@28211|Alphaproteobacteria,2K0WV@204457|Sphingomonadales	204457|Sphingomonadales	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	-	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
CMS1_k127_5536342_18	1044.EH31_04760	1.174e-13	74.0	COG1983@1|root,COG1983@2|Bacteria,1NGIB@1224|Proteobacteria,2UJTZ@28211|Alphaproteobacteria,2K7V9@204457|Sphingomonadales	204457|Sphingomonadales	KT	PspC domain	-	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	PspC
CMS1_k127_5536342_4	1470591.BW41_01320	1.605e-107	357.0	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,2TR65@28211|Alphaproteobacteria,2JZZ1@204457|Sphingomonadales	204457|Sphingomonadales	P	cation diffusion facilitator family transporter	-	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
CMS1_k127_5536342_7	1545915.JROG01000003_gene649	9.951e-71	246.0	COG0204@1|root,COG0204@2|Bacteria,1RJMS@1224|Proteobacteria,2U5TA@28211|Alphaproteobacteria,2K48I@204457|Sphingomonadales	204457|Sphingomonadales	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
CMS1_k127_5536342_5	1123240.ATVO01000004_gene912	9.701e-97	323.0	COG3752@1|root,COG3752@2|Bacteria,1MXCP@1224|Proteobacteria,2TTEP@28211|Alphaproteobacteria,2K2P6@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF1295)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
CMS1_k127_5536342_15	1112212.JH584235_gene341	1.133e-26	115.0	COG0346@1|root,COG0346@2|Bacteria,1N4MJ@1224|Proteobacteria,2UDJP@28211|Alphaproteobacteria,2K6BZ@204457|Sphingomonadales	204457|Sphingomonadales	E	Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS1_k127_5536342_6	317655.Sala_0728	2.635e-73	254.0	COG2761@1|root,COG2761@2|Bacteria,1NXUB@1224|Proteobacteria,2TRJ6@28211|Alphaproteobacteria,2K4ED@204457|Sphingomonadales	204457|Sphingomonadales	Q	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
CMS1_k127_5536342_11	1144305.PMI02_00197	2.547e-51	184.0	COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,2U982@28211|Alphaproteobacteria,2K5BT@204457|Sphingomonadales	204457|Sphingomonadales	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
CMS1_k127_5536342_16	1248760.ANFZ01000006_gene2771	1.222e-24	114.0	COG5490@1|root,COG5490@2|Bacteria,1N3RI@1224|Proteobacteria,2UDTZ@28211|Alphaproteobacteria,2K476@204457|Sphingomonadales	204457|Sphingomonadales	S	Phasin protein	-	-	-	-	-	-	-	-	-	-	-	-	Phasin_2
CMS1_k127_5536342_2	1123270.ATUR01000003_gene1202	9.359e-122	403.0	COG3424@1|root,COG3424@2|Bacteria,1MUDX@1224|Proteobacteria,2TRTX@28211|Alphaproteobacteria,2K1FI@204457|Sphingomonadales	204457|Sphingomonadales	Q	Chalcone and stilbene synthases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Chal_sti_synt_C,Chal_sti_synt_N
CMS1_k127_5536342_12	1123270.ATUR01000003_gene1201	2.759e-48	178.0	COG1755@1|root,COG1755@2|Bacteria,1RERZ@1224|Proteobacteria,2U77M@28211|Alphaproteobacteria,2K4HJ@204457|Sphingomonadales	204457|Sphingomonadales	S	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	ICMT
CMS1_k127_5536342_14	1265503.KB905162_gene3559	1.009e-29	134.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,2Q7WU@267889|Colwelliaceae	1236|Gammaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	2.7.7.65	ko:K21021	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000	-	-	-	CHASE8,EAL,GAF,GAF_2,GGDEF,HAMP,PAS_3,PAS_9
CMS1_k127_5536342_0	194867.ALBQ01000034_gene1030	0.0	1086.0	COG4773@1|root,COG4773@2|Bacteria,1Q323@1224|Proteobacteria,2TW33@28211|Alphaproteobacteria,2K10M@204457|Sphingomonadales	204457|Sphingomonadales	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
CMS1_k127_5536342_10	1123059.KB823013_gene460	2.119e-51	184.0	COG5622@1|root,COG5622@2|Bacteria,1N6UG@1224|Proteobacteria	1224|Proteobacteria	N	attachment protein	atsE	-	-	-	-	-	-	-	-	-	-	-	Host_attach
CMS1_k127_5549451_5	1545915.JROG01000010_gene2946	8.497e-34	134.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2TS19@28211|Alphaproteobacteria,2K0F8@204457|Sphingomonadales	204457|Sphingomonadales	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
CMS1_k127_5549451_4	1174684.EBMC1_03764	1.579e-39	150.0	2DRRT@1|root,32URI@2|Bacteria,1N4F0@1224|Proteobacteria,2UECN@28211|Alphaproteobacteria,2K7DV@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5549451_2	317655.Sala_2372	4.425e-148	474.0	28KEA@1|root,2ZA0J@2|Bacteria,1R5TS@1224|Proteobacteria,2U48U@28211|Alphaproteobacteria,2K5IU@204457|Sphingomonadales	204457|Sphingomonadales	H	Sulfotransferase domain	-	-	2.8.2.1	ko:K01014	ko05204,map05204	-	R01242	RC00007,RC00128	ko00000,ko00001,ko01000	-	-	-	Sulfotransfer_1
CMS1_k127_5549451_11	1081640.AGFU01000075_gene3331	8.507e-07	51.0	2CDMW@1|root,32RY1@2|Bacteria,1NAAN@1224|Proteobacteria,2U5KV@28211|Alphaproteobacteria,2K3YR@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5549451_0	1550073.JROH01000045_gene2973	3.228e-299	929.0	COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,1MUV9@1224|Proteobacteria,2TT46@28211|Alphaproteobacteria,2K26A@204457|Sphingomonadales	204457|Sphingomonadales	C	Catalyzes the reversible hydration of fumarate to (S)- malate	-	-	4.2.1.2	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase,Fumerase_C
CMS1_k127_5549451_10	1280944.HY17_14760	9.225e-15	78.0	2EGHT@1|root,33A9W@2|Bacteria,1NHZD@1224|Proteobacteria,2V70B@28211|Alphaproteobacteria,43YSN@69657|Hyphomonadaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5549451_6	1234595.C725_1689	8.19e-31	123.0	2FBS2@1|root,343WV@2|Bacteria,1NAP6@1224|Proteobacteria,2UG4Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5549451_7	156578.ATW7_10173	9.855e-20	91.0	COG4338@1|root,COG4338@2|Bacteria,1NGIS@1224|Proteobacteria,1SGEQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2256
CMS1_k127_5549451_3	317655.Sala_0373	4.781e-106	351.0	COG1028@1|root,COG1028@2|Bacteria,1QU4S@1224|Proteobacteria,2VFC9@28211|Alphaproteobacteria,2KAC5@204457|Sphingomonadales	204457|Sphingomonadales	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS1_k127_5549451_9	1545915.JROG01000004_gene1752	1.011e-15	79.0	29GQI@1|root,303NE@2|Bacteria,1NM87@1224|Proteobacteria,2UJQA@28211|Alphaproteobacteria,2KCWA@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5549451_1	1248760.ANFZ01000002_gene3100	7.149e-176	578.0	COG4206@1|root,COG4206@2|Bacteria,1QUUI@1224|Proteobacteria,2TW89@28211|Alphaproteobacteria,2K1UP@204457|Sphingomonadales	204457|Sphingomonadales	H	COG1629 Outer membrane receptor proteins, mostly Fe transport	-	-	-	-	-	-	-	-	-	-	-	-	Plug
CMS1_k127_5549451_8	1123270.ATUR01000007_gene1330	2.227e-17	83.0	COG5265@1|root,COG5265@2|Bacteria,1NSKS@1224|Proteobacteria,2UQAG@28211|Alphaproteobacteria,2K16I@204457|Sphingomonadales	204457|Sphingomonadales	V	ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS1_k127_5551713_5	383381.EH30_10110	6.216e-123	398.0	COG1960@1|root,COG1960@2|Bacteria,1MUBH@1224|Proteobacteria,2TSKH@28211|Alphaproteobacteria,2K0KB@204457|Sphingomonadales	204457|Sphingomonadales	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS1_k127_5551713_1	161528.ED21_19172	1.462e-228	711.0	COG1960@1|root,COG1960@2|Bacteria,1MVJC@1224|Proteobacteria,2TQRA@28211|Alphaproteobacteria,2K01U@204457|Sphingomonadales	204457|Sphingomonadales	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS1_k127_5551713_6	1545915.JROG01000003_gene663	1.797e-100	344.0	COG1714@1|root,COG1714@2|Bacteria,1RAZN@1224|Proteobacteria,2U6W9@28211|Alphaproteobacteria,2K24C@204457|Sphingomonadales	204457|Sphingomonadales	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
CMS1_k127_5551713_4	702113.PP1Y_AT3874	1.526e-134	439.0	COG1300@1|root,COG1300@2|Bacteria,1Q1GN@1224|Proteobacteria,2U06S@28211|Alphaproteobacteria,2JZZD@204457|Sphingomonadales	204457|Sphingomonadales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIM
CMS1_k127_5551713_2	1248760.ANFZ01000009_gene864	2.823e-169	544.0	COG1721@1|root,COG1721@2|Bacteria,1MXDI@1224|Proteobacteria,2TU87@28211|Alphaproteobacteria,2K038@204457|Sphingomonadales	204457|Sphingomonadales	S	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CMS1_k127_5551713_3	1545915.JROG01000003_gene660	2.071e-146	480.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,2TR0T@28211|Alphaproteobacteria,2K1NZ@204457|Sphingomonadales	204457|Sphingomonadales	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS1_k127_5551713_7	1248760.ANFZ01000009_gene862	7.764e-96	328.0	2952T@1|root,2ZSFJ@2|Bacteria,1RGF9@1224|Proteobacteria,2U83E@28211|Alphaproteobacteria,2K2TA@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5551713_9	1545915.JROG01000003_gene658	2.179e-57	209.0	2C58E@1|root,32V5I@2|Bacteria,1N13T@1224|Proteobacteria,2UHTM@28211|Alphaproteobacteria,2KCHT@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5551713_10	1248760.ANFZ01000009_gene860	3.862e-52	193.0	2E7B7@1|root,331UM@2|Bacteria,1N6KN@1224|Proteobacteria,2UD50@28211|Alphaproteobacteria,2K5JV@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5551713_8	383381.EH30_10025	8.279e-72	246.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,2U6Z6@28211|Alphaproteobacteria,2K4B2@204457|Sphingomonadales	204457|Sphingomonadales	C	COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
CMS1_k127_5551713_0	314225.ELI_11225	1.343e-267	844.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2TQVK@28211|Alphaproteobacteria,2K25R@204457|Sphingomonadales	204457|Sphingomonadales	C	aerobic-type carbon monoxide dehydrogenase, large subunit CoxL	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
CMS1_k127_5551713_11	314225.ELI_11220	1.245e-29	125.0	COG3474@1|root,COG3474@2|Bacteria,1MZGS@1224|Proteobacteria,2UIZ6@28211|Alphaproteobacteria,2KCWK@204457|Sphingomonadales	204457|Sphingomonadales	C	Cytochrome c	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C
CMS1_k127_5551713_12	1379701.JPJC01000112_gene514	8.462e-29	124.0	COG2068@1|root,COG2068@2|Bacteria,1MW0X@1224|Proteobacteria,2TR5D@28211|Alphaproteobacteria,2K40X@204457|Sphingomonadales	204457|Sphingomonadales	S	MobA-like NTP transferase domain	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
CMS1_k127_5561997_5	1335760.ASTG01000003_gene1573	7.188e-77	268.0	COG4872@1|root,COG4872@2|Bacteria,1N4JN@1224|Proteobacteria,2UE2X@28211|Alphaproteobacteria,2K8KQ@204457|Sphingomonadales	204457|Sphingomonadales	S	Predicted membrane protein (DUF2157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2157
CMS1_k127_5561997_8	652103.Rpdx1_3795	3.144e-44	169.0	COG1073@1|root,COG1765@1|root,COG1073@2|Bacteria,COG1765@2|Bacteria,1N2BT@1224|Proteobacteria,2TQN7@28211|Alphaproteobacteria,3JQSS@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	OsmC-like protein	MA20_16590	-	-	ko:K06889,ko:K07397	-	-	-	-	ko00000	-	-	-	Hydrolase_4,OsmC
CMS1_k127_5561997_0	1174684.EBMC1_15332	0.0	1084.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,2TQPM@28211|Alphaproteobacteria,2K017@204457|Sphingomonadales	204457|Sphingomonadales	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
CMS1_k127_5561997_6	1123270.ATUR01000004_gene1577	3.117e-56	198.0	COG1487@1|root,COG1487@2|Bacteria,1MZCD@1224|Proteobacteria,2UMQN@28211|Alphaproteobacteria,2KA8P@204457|Sphingomonadales	204457|Sphingomonadales	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
CMS1_k127_5561997_10	1123270.ATUR01000004_gene1578	3.736e-32	126.0	COG0864@1|root,COG0864@2|Bacteria,1N729@1224|Proteobacteria,2UFDM@28211|Alphaproteobacteria,2K7F0@204457|Sphingomonadales	204457|Sphingomonadales	K	Ribbon-helix-helix protein, copG family	-	-	-	-	-	-	-	-	-	-	-	-	RHH_1
CMS1_k127_5561997_9	1123270.ATUR01000004_gene1579	7.065e-42	164.0	2DPZY@1|root,3345E@2|Bacteria,1N9A1@1224|Proteobacteria,2UFDG@28211|Alphaproteobacteria,2K7G8@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5561997_1	1123270.ATUR01000004_gene1580	1.49e-208	658.0	COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,2TQPS@28211|Alphaproteobacteria,2K246@204457|Sphingomonadales	204457|Sphingomonadales	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,NTP_transf_3
CMS1_k127_5561997_2	1112214.AHIS01000099_gene1421	9.094e-122	406.0	28JAH@1|root,2Z95A@2|Bacteria,1MXKT@1224|Proteobacteria,2U1QQ@28211|Alphaproteobacteria,2K0RI@204457|Sphingomonadales	204457|Sphingomonadales	S	Uncharacterised nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
CMS1_k127_5561997_3	452662.SJA_C1-28810	9.085e-119	389.0	COG5265@1|root,COG5265@2|Bacteria,1MWU5@1224|Proteobacteria,2U7S8@28211|Alphaproteobacteria,2K15C@204457|Sphingomonadales	204457|Sphingomonadales	O	HPr kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5561997_11	1123270.ATUR01000004_gene1586	1.016e-14	77.0	2AM5A@1|root,31BZK@2|Bacteria,1P9KA@1224|Proteobacteria,2UXS5@28211|Alphaproteobacteria,2K6U0@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5561997_7	1123270.ATUR01000004_gene1587	1.04e-52	189.0	2AK6Y@1|root,300PR@2|Bacteria,1NUJM@1224|Proteobacteria,2URGJ@28211|Alphaproteobacteria,2KDMG@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5561997_4	1112216.JH594425_gene3467	7.347e-118	396.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,2TR46@28211|Alphaproteobacteria,2K1ZG@204457|Sphingomonadales	204457|Sphingomonadales	T	Histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_8
CMS1_k127_5561997_12	1112212.JH584235_gene845	1.235e-09	61.0	COG0226@1|root,COG0226@2|Bacteria,1MUH9@1224|Proteobacteria,2TR1C@28211|Alphaproteobacteria,2K0M7@204457|Sphingomonadales	204457|Sphingomonadales	P	Phosphate ABC transporter substrate-binding protein	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
CMS1_k127_556535_6	314225.ELI_11060	0.0004308	46.0	COG0760@1|root,COG0760@2|Bacteria,1R4ZR@1224|Proteobacteria,2U874@28211|Alphaproteobacteria,2K179@204457|Sphingomonadales	204457|Sphingomonadales	O	COG0760 Parvulin-like peptidyl-prolyl isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase_2
CMS1_k127_556535_2	383381.EH30_11730	1.756e-243	768.0	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,2TSGX@28211|Alphaproteobacteria,2K8V1@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
CMS1_k127_556535_1	317655.Sala_3166	5.104e-246	769.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,2TSR0@28211|Alphaproteobacteria,2JZXX@204457|Sphingomonadales	204457|Sphingomonadales	Q	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
CMS1_k127_556535_0	1248760.ANFZ01000002_gene2988	1.462e-276	861.0	COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,2TSUQ@28211|Alphaproteobacteria,2K0GU@204457|Sphingomonadales	204457|Sphingomonadales	O	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
CMS1_k127_556535_4	1545915.JROG01000004_gene1703	9.783e-79	272.0	COG2207@1|root,COG2207@2|Bacteria,1N4K1@1224|Proteobacteria,2UF1F@28211|Alphaproteobacteria,2KDQH@204457|Sphingomonadales	204457|Sphingomonadales	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
CMS1_k127_556535_5	1090320.KB900605_gene3264	1.987e-56	200.0	COG1959@1|root,COG1959@2|Bacteria,1N0E2@1224|Proteobacteria,2UAVK@28211|Alphaproteobacteria,2K421@204457|Sphingomonadales	204457|Sphingomonadales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
CMS1_k127_556535_3	1123269.NX02_24685	6.329e-153	488.0	COG0719@1|root,COG0719@2|Bacteria,1MVKY@1224|Proteobacteria,2TRU6@28211|Alphaproteobacteria,2K196@204457|Sphingomonadales	204457|Sphingomonadales	O	ABC-type transport system involved in Fe-S cluster assembly, permease component	sufB	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
CMS1_k127_5576848_0	1144307.PMI04_02473	1.514e-142	454.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,2TR5H@28211|Alphaproteobacteria,2K1KK@204457|Sphingomonadales	204457|Sphingomonadales	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
CMS1_k127_5576848_3	1346791.M529_12500	5.302e-33	132.0	COG2847@1|root,COG2847@2|Bacteria,1N3BG@1224|Proteobacteria,2UM57@28211|Alphaproteobacteria,2K60Y@204457|Sphingomonadales	204457|Sphingomonadales	S	Copper chaperone PCu(A)C	-	-	-	ko:K09796	-	-	-	-	ko00000,ko03110	-	-	-	PCuAC
CMS1_k127_5576848_2	1114964.L485_06545	1.663e-57	203.0	COG4253@1|root,COG4253@2|Bacteria,1RJSI@1224|Proteobacteria,2UAVI@28211|Alphaproteobacteria,2K54I@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5576848_1	317655.Sala_1677	7.863e-94	313.0	COG3047@1|root,COG3047@2|Bacteria,1NUZJ@1224|Proteobacteria,2TRGI@28211|Alphaproteobacteria,2K2CV@204457|Sphingomonadales	204457|Sphingomonadales	M	OmpW family	-	-	-	ko:K07275	-	-	-	-	ko00000	-	-	-	OmpW
CMS1_k127_5576848_4	317655.Sala_0454	1.334e-23	100.0	COG0534@1|root,COG0534@2|Bacteria,1MUAM@1224|Proteobacteria,2TSDU@28211|Alphaproteobacteria,2K152@204457|Sphingomonadales	204457|Sphingomonadales	V	Na -driven multidrug efflux pump	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
CMS1_k127_5585408_2	1007104.SUS17_86	1.297e-194	618.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,2JZVD@204457|Sphingomonadales	204457|Sphingomonadales	C	belongs to the aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS1_k127_5585408_0	1248760.ANFZ01000013_gene1849	8.005e-268	833.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2TSB1@28211|Alphaproteobacteria,2K0EY@204457|Sphingomonadales	204457|Sphingomonadales	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS1_k127_5585408_14	1122970.AUHC01000015_gene2539	2.224e-36	145.0	COG1971@1|root,COG1971@2|Bacteria,1NWBY@1224|Proteobacteria,2U6TQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Probably functions as a manganese efflux pump	mntP	-	-	-	-	-	-	-	-	-	-	-	Mntp
CMS1_k127_5585408_12	1545915.JROG01000003_gene1547	4.915e-50	184.0	COG2947@1|root,COG2947@2|Bacteria,1RHRU@1224|Proteobacteria,2U71N@28211|Alphaproteobacteria,2K5EU@204457|Sphingomonadales	204457|Sphingomonadales	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
CMS1_k127_5585408_15	991.IW20_18420	5.149e-26	114.0	COG2335@1|root,COG2335@2|Bacteria,4NMAH@976|Bacteroidetes,1I17E@117743|Flavobacteriia,2NSUH@237|Flavobacterium	976|Bacteroidetes	M	Fasciclin	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
CMS1_k127_5585408_10	1123035.ARLA01000027_gene341	6.091e-53	193.0	COG2335@1|root,COG2335@2|Bacteria,4NMAH@976|Bacteroidetes,1I224@117743|Flavobacteriia,4C2NT@83612|Psychroflexus	976|Bacteroidetes	M	Four repeated domains in the Fasciclin I family of proteins, present in many other contexts.	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
CMS1_k127_5585408_7	627192.SLG_21350	8.822e-76	264.0	COG1028@1|root,COG1028@2|Bacteria,1MUUV@1224|Proteobacteria,2TR0A@28211|Alphaproteobacteria,2K33T@204457|Sphingomonadales	204457|Sphingomonadales	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS1_k127_5585408_11	452662.SJA_C1-14840	3.633e-51	184.0	COG1539@1|root,COG1539@2|Bacteria,1RKNS@1224|Proteobacteria,2UAD6@28211|Alphaproteobacteria,2K58X@204457|Sphingomonadales	204457|Sphingomonadales	H	dihydroneopterin aldolase	-	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
CMS1_k127_5585408_4	452662.SJA_C1-06780	2.551e-141	453.0	COG1092@1|root,COG1092@2|Bacteria,1QSD4@1224|Proteobacteria,2TUFT@28211|Alphaproteobacteria,2K037@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the methyltransferase superfamily	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
CMS1_k127_5585408_1	1219035.NT2_01_04330	1.167e-231	724.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,2TT0D@28211|Alphaproteobacteria,2K0KX@204457|Sphingomonadales	204457|Sphingomonadales	E	Threonine synthase	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_synth_N
CMS1_k127_5585408_8	1248760.ANFZ01000021_gene365	3.591e-75	259.0	COG3346@1|root,COG3346@2|Bacteria,1RIJQ@1224|Proteobacteria,2UA1G@28211|Alphaproteobacteria,2K34C@204457|Sphingomonadales	204457|Sphingomonadales	S	SURF1-like protein	-	-	-	ko:K14998	-	-	-	-	ko00000,ko03029	3.D.4.8	-	-	SURF1
CMS1_k127_5585408_13	13689.BV96_04177	4.928e-45	166.0	COG5349@1|root,COG5349@2|Bacteria,1N0WU@1224|Proteobacteria,2UCE7@28211|Alphaproteobacteria,2K61Z@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF983)	-	-	-	-	-	-	-	-	-	-	-	-	DUF983
CMS1_k127_5585408_3	1030157.AFMP01000040_gene1401	2.565e-155	493.0	COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,2TQWA@28211|Alphaproteobacteria,2JZW3@204457|Sphingomonadales	204457|Sphingomonadales	C	Heme copper-type cytochrome quinol oxidase, subunit 3	ctaE	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
CMS1_k127_5585408_9	1545915.JROG01000003_gene1484	2.666e-70	245.0	COG3175@1|root,COG3175@2|Bacteria,1RDTU@1224|Proteobacteria,2U6ZT@28211|Alphaproteobacteria,2K3WU@204457|Sphingomonadales	204457|Sphingomonadales	O	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I	ctaG	-	-	ko:K02258	ko00190,ko01100,ko04714,map00190,map01100,map04714	M00154	-	-	ko00000,ko00001,ko00002,ko03029	3.D.4.8	-	-	CtaG_Cox11
CMS1_k127_5585408_16	1479239.JQMU01000001_gene2486	0.0009364	50.0	2AGTM@1|root,30B0X@2|Bacteria,1QTAI@1224|Proteobacteria,2V1VG@28211|Alphaproteobacteria,2KC8J@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5585408_6	1545915.JROG01000003_gene1486	1.011e-123	403.0	COG0109@1|root,COG0109@2|Bacteria,1MW3S@1224|Proteobacteria,2TRD8@28211|Alphaproteobacteria,2K01V@204457|Sphingomonadales	204457|Sphingomonadales	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
CMS1_k127_5585408_5	1545915.JROG01000003_gene1487	7.287e-135	430.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,2TQP1@28211|Alphaproteobacteria,2K034@204457|Sphingomonadales	204457|Sphingomonadales	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	ctaD	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
CMS1_k127_5602627_2	46429.BV95_03380	3.171e-105	346.0	COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,2TUG7@28211|Alphaproteobacteria,2K163@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
CMS1_k127_5602627_7	1248760.ANFZ01000009_gene1396	4.601e-35	146.0	2D5TK@1|root,3133H@2|Bacteria,1NRIX@1224|Proteobacteria,2UQRX@28211|Alphaproteobacteria,2K6JR@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5602627_5	1123270.ATUR01000002_gene2202	2.218e-47	171.0	COG0633@1|root,COG0633@2|Bacteria,1N261@1224|Proteobacteria,2UC7B@28211|Alphaproteobacteria,2K5DE@204457|Sphingomonadales	204457|Sphingomonadales	C	ferredoxin	-	-	-	ko:K04755	-	-	-	-	ko00000	-	-	-	Fer2
CMS1_k127_5602627_4	1545915.JROG01000003_gene1522	8.994e-93	309.0	COG0122@1|root,COG0122@2|Bacteria,1MX9C@1224|Proteobacteria,2TVJ7@28211|Alphaproteobacteria,2K0I0@204457|Sphingomonadales	204457|Sphingomonadales	L	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase	-	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
CMS1_k127_5602627_1	566466.NOR53_1606	1.983e-111	366.0	COG4221@1|root,COG4221@2|Bacteria,1NTNU@1224|Proteobacteria,1T3IJ@1236|Gammaproteobacteria,1J8TK@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	related to short-chain alcohol	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS1_k127_5602627_6	1537715.JQFJ01000002_gene1539	2.513e-46	172.0	2BU6D@1|root,3101F@2|Bacteria,1MYRB@1224|Proteobacteria,2UAVA@28211|Alphaproteobacteria,2KD9N@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5602627_0	1545915.JROG01000003_gene1520	9.171e-208	660.0	COG1174@1|root,COG1732@1|root,COG1174@2|Bacteria,COG1732@2|Bacteria,1MX8D@1224|Proteobacteria,2VETG@28211|Alphaproteobacteria,2KDWN@204457|Sphingomonadales	204457|Sphingomonadales	P	Substrate binding domain of ABC-type glycine betaine transport system	-	-	-	ko:K05845,ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1,OpuAC
CMS1_k127_5602627_3	1248760.ANFZ01000013_gene1876	2.639e-94	316.0	COG1125@1|root,COG1125@2|Bacteria,1QVTN@1224|Proteobacteria,2TYSS@28211|Alphaproteobacteria,2KEN5@204457|Sphingomonadales	204457|Sphingomonadales	E	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
CMS1_k127_5604556_1	745310.G432_02740	6.038e-215	675.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,2TRWB@28211|Alphaproteobacteria,2K00K@204457|Sphingomonadales	204457|Sphingomonadales	E	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
CMS1_k127_5604556_2	1545915.JROG01000003_gene1358	2.638e-170	557.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,2TRYU@28211|Alphaproteobacteria,2K0KV@204457|Sphingomonadales	204457|Sphingomonadales	O	peptidylprolyl isomerase	-	-	5.2.1.8	ko:K01802,ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,SurA_N_3
CMS1_k127_5604556_3	1248760.ANFZ01000021_gene457	3.253e-93	312.0	COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,2TS6I@28211|Alphaproteobacteria,2K1PI@204457|Sphingomonadales	204457|Sphingomonadales	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
CMS1_k127_5604556_5	158500.BV97_00643	4.38e-30	123.0	COG1314@1|root,COG1314@2|Bacteria,1N8MF@1224|Proteobacteria,2UCIP@28211|Alphaproteobacteria,2K5YU@204457|Sphingomonadales	204457|Sphingomonadales	U	Preprotein translocase subunit SecG	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
CMS1_k127_5604556_0	1248760.ANFZ01000021_gene459	4.707e-301	928.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,2TS4Y@28211|Alphaproteobacteria,2K005@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
CMS1_k127_5604556_4	1545915.JROG01000003_gene1354	2.858e-87	294.0	COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,2TT42@28211|Alphaproteobacteria,2K3CE@204457|Sphingomonadales	204457|Sphingomonadales	K	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CMS1_k127_5608645_9	629773.AORY01000001_gene2142	2.681e-25	105.0	COG0625@1|root,COG0625@2|Bacteria,1MXHH@1224|Proteobacteria,2TVGY@28211|Alphaproteobacteria,2K0MF@204457|Sphingomonadales	204457|Sphingomonadales	O	Glutathione S-transferase	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N
CMS1_k127_5608645_0	1248760.ANFZ01000009_gene1535	0.0	1369.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,2TQV4@28211|Alphaproteobacteria,2K28K@204457|Sphingomonadales	204457|Sphingomonadales	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
CMS1_k127_5608645_1	1123270.ATUR01000003_gene1090	1.131e-252	792.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,2TRC5@28211|Alphaproteobacteria,2K061@204457|Sphingomonadales	204457|Sphingomonadales	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N
CMS1_k127_5608645_4	685035.ADAE01000002_gene2720	2.766e-139	478.0	COG0654@1|root,COG0654@2|Bacteria,1P1NX@1224|Proteobacteria,2TRZX@28211|Alphaproteobacteria,2K20R@204457|Sphingomonadales	204457|Sphingomonadales	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
CMS1_k127_5608645_2	1248760.ANFZ01000009_gene1519	3.275e-242	751.0	COG0538@1|root,COG0538@2|Bacteria,1MUIB@1224|Proteobacteria,2TQWD@28211|Alphaproteobacteria,2K05F@204457|Sphingomonadales	204457|Sphingomonadales	C	Belongs to the isocitrate and isopropylmalate dehydrogenases family	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
CMS1_k127_5608645_5	1248760.ANFZ01000009_gene1520	7.999e-115	374.0	COG0688@1|root,COG0688@2|Bacteria,1MW45@1224|Proteobacteria,2TRMG@28211|Alphaproteobacteria,2K019@204457|Sphingomonadales	204457|Sphingomonadales	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
CMS1_k127_5608645_6	1248760.ANFZ01000009_gene1521	1.381e-109	360.0	COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,2TUF7@28211|Alphaproteobacteria,2K1B9@204457|Sphingomonadales	204457|Sphingomonadales	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_tran_2,CDP-OH_P_transf
CMS1_k127_5608645_3	1044.EH31_14030	4.37e-151	490.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,2U139@28211|Alphaproteobacteria,2K18J@204457|Sphingomonadales	204457|Sphingomonadales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
CMS1_k127_5608645_7	1545915.JROG01000009_gene2799	7.026e-103	338.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2TS3W@28211|Alphaproteobacteria,2JZYQ@204457|Sphingomonadales	204457|Sphingomonadales	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_5608645_8	1044.EH31_14020	7.744e-102	339.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,2TW3U@28211|Alphaproteobacteria,2K1A6@204457|Sphingomonadales	204457|Sphingomonadales	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS1_k127_5637966_3	158500.BV97_00203	2.571e-11	67.0	2AHNU@1|root,3180V@2|Bacteria,1NMIQ@1224|Proteobacteria,2UN1I@28211|Alphaproteobacteria,2K83F@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5637966_0	1248760.ANFZ01000002_gene3164	0.0	1180.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,2TS2B@28211|Alphaproteobacteria,2K04E@204457|Sphingomonadales	204457|Sphingomonadales	L	DNA helicase	uvrD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
CMS1_k127_5637966_1	1219035.NT2_02_04070	1.624e-26	109.0	COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,2U70Y@28211|Alphaproteobacteria,2K3X3@204457|Sphingomonadales	204457|Sphingomonadales	L	Methyltransferase	-	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
CMS1_k127_5642678_1	1502850.FG91_01973	1.508e-127	421.0	COG2311@1|root,COG2311@2|Bacteria,1MWHW@1224|Proteobacteria,2U310@28211|Alphaproteobacteria,2K0I8@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF418)	-	-	-	ko:K07148	-	-	-	-	ko00000	-	-	-	DUF418
CMS1_k127_5642678_3	317655.Sala_2200	6.999e-96	318.0	COG0778@1|root,COG0778@2|Bacteria,1MY39@1224|Proteobacteria,2TTZC@28211|Alphaproteobacteria,2K31F@204457|Sphingomonadales	204457|Sphingomonadales	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CMS1_k127_5642678_2	1545915.JROG01000001_gene540	2.522e-107	354.0	COG5031@1|root,COG5031@2|Bacteria,1RGXT@1224|Proteobacteria,2U0IY@28211|Alphaproteobacteria,2KCGW@204457|Sphingomonadales	204457|Sphingomonadales	H	Coenzyme Q (ubiquinone) biosynthesis protein Coq4	-	-	-	ko:K18586	-	-	-	-	ko00000	-	-	-	Coq4
CMS1_k127_5642678_6	1123269.NX02_29495	5.815e-40	151.0	2DMMQ@1|root,32SHK@2|Bacteria,1N2WS@1224|Proteobacteria,2UC62@28211|Alphaproteobacteria,2K5BZ@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3052
CMS1_k127_5642678_8	1174684.EBMC1_12846	5.071e-29	119.0	COG2852@1|root,COG2852@2|Bacteria,1N0QU@1224|Proteobacteria,2UHP2@28211|Alphaproteobacteria,2KE3I@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
CMS1_k127_5642678_0	1346791.M529_11295	0.0	1111.0	COG0046@1|root,COG0046@2|Bacteria,1MYN4@1224|Proteobacteria,2TRGM@28211|Alphaproteobacteria,2K25A@204457|Sphingomonadales	204457|Sphingomonadales	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
CMS1_k127_5642678_4	1248916.ANFY01000004_gene1858	5.203e-93	310.0	COG3917@1|root,COG3917@2|Bacteria,1RA6I@1224|Proteobacteria,2U5JB@28211|Alphaproteobacteria,2K4JJ@204457|Sphingomonadales	204457|Sphingomonadales	Q	2-hydroxychromene-2-carboxylate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
CMS1_k127_5642678_9	228405.HNE_2096	1.017e-08	61.0	COG3313@1|root,COG3313@2|Bacteria,1NGD5@1224|Proteobacteria,2UJKX@28211|Alphaproteobacteria,43YVQ@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1289)	-	-	-	ko:K06938	-	-	-	-	ko00000	-	-	-	DUF1289
CMS1_k127_5642678_5	1044.EH31_01230	1.656e-45	173.0	COG4852@1|root,COG4852@2|Bacteria,1MZHP@1224|Proteobacteria,2UBSF@28211|Alphaproteobacteria,2K61I@204457|Sphingomonadales	204457|Sphingomonadales	S	Predicted membrane protein (DUF2177)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2177
CMS1_k127_5642678_7	685035.ADAE01000018_gene595	2.241e-34	134.0	arCOG09454@1|root,30G4A@2|Bacteria,1N61J@1224|Proteobacteria,2UEFT@28211|Alphaproteobacteria,2K4KH@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5643312_3	1346791.M529_02030	3.909e-190	595.0	COG4547@1|root,COG4547@2|Bacteria,1MX11@1224|Proteobacteria,2TS4N@28211|Alphaproteobacteria,2JZUK@204457|Sphingomonadales	204457|Sphingomonadales	H	Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide 5, 6-dimethylbenzimidazole phosphoribosyltransferase)	-	-	6.6.1.2	ko:K09883	ko00860,ko01100,map00860,map01100	-	R05227	RC02000	ko00000,ko00001,ko01000	-	-	-	CobT,CobT_C
CMS1_k127_5643312_4	1545915.JROG01000003_gene1317	8.695e-102	336.0	COG0778@1|root,COG0778@2|Bacteria,1PG8V@1224|Proteobacteria,2U59W@28211|Alphaproteobacteria,2K283@204457|Sphingomonadales	204457|Sphingomonadales	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CMS1_k127_5643312_0	1044.EH31_05190	0.0	1042.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1R81Z@1224|Proteobacteria,2U2DW@28211|Alphaproteobacteria,2K1YH@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	CHAT
CMS1_k127_5643312_1	1248760.ANFZ01000009_gene1550	5.379e-256	807.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,2TRTY@28211|Alphaproteobacteria,2K1MH@204457|Sphingomonadales	204457|Sphingomonadales	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
CMS1_k127_5643312_6	279238.Saro_2385	4.077e-51	192.0	2ENSP@1|root,33GDV@2|Bacteria,1RDDU@1224|Proteobacteria,2U8WK@28211|Alphaproteobacteria,2KDDV@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5643312_2	1044.EH31_05185	5.814e-202	645.0	COG2831@1|root,COG2831@2|Bacteria,1R6KX@1224|Proteobacteria,2TUEN@28211|Alphaproteobacteria,2K29V@204457|Sphingomonadales	204457|Sphingomonadales	U	COG2831 Hemolysin activation secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	POTRA_2,ShlB
CMS1_k127_5643312_5	1219045.BV98_003853	2.694e-57	211.0	COG3210@1|root,COG3210@2|Bacteria,1R8TG@1224|Proteobacteria,2U41V@28211|Alphaproteobacteria,2K1DN@204457|Sphingomonadales	204457|Sphingomonadales	U	COG3210 Large exoproteins involved in heme utilization or adhesion	-	-	-	-	-	-	-	-	-	-	-	-	Haemagg_act
CMS1_k127_5730983_6	1248760.ANFZ01000002_gene3193	7.014e-97	320.0	COG3000@1|root,COG3000@2|Bacteria,1NXAF@1224|Proteobacteria,2TRF0@28211|Alphaproteobacteria,2K0X1@204457|Sphingomonadales	204457|Sphingomonadales	I	sterol desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
CMS1_k127_5730983_3	1545915.JROG01000009_gene2840	1.504e-126	415.0	COG0654@1|root,COG0654@2|Bacteria,1N8DE@1224|Proteobacteria,2TU88@28211|Alphaproteobacteria,2K0B6@204457|Sphingomonadales	204457|Sphingomonadales	CH	Lycopene cyclase protein	crtY	-	5.5.1.19	ko:K06443	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00097	R03824,R04801,R05341,R06962,R07856	RC01004,RC01964	ko00000,ko00001,ko00002,ko01000	-	-	-	Lycopene_cycl
CMS1_k127_5730983_0	1248760.ANFZ01000002_gene2994	2.861e-268	831.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,2TSR0@28211|Alphaproteobacteria,2K17H@204457|Sphingomonadales	204457|Sphingomonadales	Q	Phytoene dehydrogenase	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
CMS1_k127_5730983_4	1123270.ATUR01000004_gene1561	2.187e-111	369.0	COG1562@1|root,COG1562@2|Bacteria,1MX4W@1224|Proteobacteria,2TTI0@28211|Alphaproteobacteria,2K2BH@204457|Sphingomonadales	204457|Sphingomonadales	I	Phytoene synthase	crtB	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
CMS1_k127_5730983_7	1248760.ANFZ01000019_gene1767	9.536e-76	262.0	COG0483@1|root,COG0483@2|Bacteria,1MV4W@1224|Proteobacteria,2TV4R@28211|Alphaproteobacteria,2K171@204457|Sphingomonadales	204457|Sphingomonadales	G	Inositol monophosphatase	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
CMS1_k127_5730983_2	1123269.NX02_25210	2.859e-180	574.0	COG0312@1|root,COG0312@2|Bacteria,1MUVW@1224|Proteobacteria,2TSAV@28211|Alphaproteobacteria,2K048@204457|Sphingomonadales	204457|Sphingomonadales	S	modulator of DNA gyrase	pmbA	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
CMS1_k127_5730983_8	1545915.JROG01000008_gene3531	2.831e-25	110.0	2AMZ5@1|root,31CWB@2|Bacteria,1N5R3@1224|Proteobacteria,2UDB9@28211|Alphaproteobacteria,2K669@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5730983_1	1502850.FG91_03770	1.728e-198	627.0	COG1902@1|root,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,2TQPY@28211|Alphaproteobacteria,2K3D5@204457|Sphingomonadales	204457|Sphingomonadales	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
CMS1_k127_5730983_5	1207055.C100_14305	5.51e-108	353.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,2K001@204457|Sphingomonadales	204457|Sphingomonadales	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
CMS1_k127_5739677_8	1248760.ANFZ01000009_gene1500	1.982e-60	214.0	COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,2UBUC@28211|Alphaproteobacteria,2K4K3@204457|Sphingomonadales	204457|Sphingomonadales	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
CMS1_k127_5739677_9	158500.BV97_02143	3.628e-44	166.0	2C068@1|root,30N9J@2|Bacteria,1RG08@1224|Proteobacteria,2U9FG@28211|Alphaproteobacteria,2K56D@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF3035)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3035
CMS1_k127_5739677_10	392499.Swit_5352	8.167e-16	81.0	COG1872@1|root,COG1872@2|Bacteria,1NGWG@1224|Proteobacteria,2UKJF@28211|Alphaproteobacteria,2K7NF@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
CMS1_k127_5739677_0	685778.AORL01000022_gene1653	7.122e-272	850.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,2TRMY@28211|Alphaproteobacteria,2K0R5@204457|Sphingomonadales	204457|Sphingomonadales	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
CMS1_k127_5739677_1	1123270.ATUR01000004_gene1784	1.304e-203	649.0	COG5360@1|root,COG5360@2|Bacteria,1MUJ4@1224|Proteobacteria,2TR5G@28211|Alphaproteobacteria,2K1RQ@204457|Sphingomonadales	204457|Sphingomonadales	S	Heparinase	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III
CMS1_k127_5739677_4	1123270.ATUR01000004_gene1783	1.557e-116	377.0	COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,2TQKR@28211|Alphaproteobacteria,2K1ZB@204457|Sphingomonadales	204457|Sphingomonadales	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
CMS1_k127_5739677_2	1123270.ATUR01000004_gene1782	7.428e-147	479.0	COG0144@1|root,COG0144@2|Bacteria,1MWPE@1224|Proteobacteria,2TSIA@28211|Alphaproteobacteria,2K0U7@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	-	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
CMS1_k127_5739677_5	1122135.KB893146_gene1433	2.184e-116	380.0	COG0357@1|root,COG0357@2|Bacteria,1R2JS@1224|Proteobacteria,2TZMC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_32
CMS1_k127_5739677_3	161528.ED21_20189	7.927e-131	422.0	COG0861@1|root,COG0861@2|Bacteria,1MWC9@1224|Proteobacteria,2TTT6@28211|Alphaproteobacteria,2K1P9@204457|Sphingomonadales	204457|Sphingomonadales	P	COG0861 Membrane protein TerC, possibly involved in tellurium resistance	-	-	-	-	-	-	-	-	-	-	-	-	TerC
CMS1_k127_5739677_6	685035.ADAE01000017_gene304	1.235e-94	316.0	COG0558@1|root,COG0558@2|Bacteria,1RAA0@1224|Proteobacteria,2U5VB@28211|Alphaproteobacteria,2K46F@204457|Sphingomonadales	204457|Sphingomonadales	I	CDP-alcohol phosphatidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CDP-OH_P_transf
CMS1_k127_5739677_7	1114964.L485_13540	7.269e-64	222.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,2TS3N@28211|Alphaproteobacteria,2K0A4@204457|Sphingomonadales	204457|Sphingomonadales	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
CMS1_k127_5750874_2	1114964.L485_22270	7.068e-44	163.0	COG5001@1|root,COG5001@2|Bacteria,1QWUF@1224|Proteobacteria,2TX5E@28211|Alphaproteobacteria,2KEGM@204457|Sphingomonadales	204457|Sphingomonadales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
CMS1_k127_5750874_0	1030157.AFMP01000044_gene1788	0.0	1549.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,2TR2H@28211|Alphaproteobacteria,2K07V@204457|Sphingomonadales	204457|Sphingomonadales	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
CMS1_k127_5750874_3	1248760.ANFZ01000009_gene846	1.09e-35	138.0	COG2938@1|root,COG2938@2|Bacteria,1N6SJ@1224|Proteobacteria,2VCGJ@28211|Alphaproteobacteria,2K5W5@204457|Sphingomonadales	204457|Sphingomonadales	S	Flavinator of succinate dehydrogenase	-	-	-	ko:K09159	-	-	-	-	ko00000,ko02048	-	-	-	Sdh5
CMS1_k127_5750874_1	392499.Swit_1516	5.487e-258	807.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,2TR86@28211|Alphaproteobacteria,2K0MC@204457|Sphingomonadales	204457|Sphingomonadales	L	ATP-dependent DNA helicase RecG	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
CMS1_k127_5758207_0	1192759.AKIB01000002_gene684	2.386e-225	704.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,2TR5H@28211|Alphaproteobacteria,2K1KK@204457|Sphingomonadales	204457|Sphingomonadales	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
CMS1_k127_5758207_1	1537715.JQFJ01000002_gene2266	1.413e-174	555.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,2TRZ1@28211|Alphaproteobacteria,2K1EY@204457|Sphingomonadales	204457|Sphingomonadales	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
CMS1_k127_5758207_3	1545915.JROG01000009_gene2713	1.86e-86	290.0	2DMBA@1|root,32GFI@2|Bacteria,1RM38@1224|Proteobacteria,2U6JC@28211|Alphaproteobacteria,2K43S@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5758207_2	1044.EH31_01830	3.286e-91	311.0	COG0491@1|root,COG0491@2|Bacteria,1PKW8@1224|Proteobacteria,2TUW8@28211|Alphaproteobacteria,2K4IM@204457|Sphingomonadales	204457|Sphingomonadales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS1_k127_5758207_4	1335760.ASTG01000012_gene520	8.729e-57	200.0	COG1752@1|root,COG1752@2|Bacteria,1MWH2@1224|Proteobacteria,2TU16@28211|Alphaproteobacteria,2K0ET@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF3376)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3376,Patatin
CMS1_k127_5760123_4	237727.NAP1_10908	2.885e-86	288.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,2TRGU@28211|Alphaproteobacteria,2K07K@204457|Sphingomonadales	204457|Sphingomonadales	BQ	histone deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
CMS1_k127_5760123_0	1248917.ANFX01000040_gene797	1.646e-308	951.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,2TSZZ@28211|Alphaproteobacteria,2JZXP@204457|Sphingomonadales	204457|Sphingomonadales	Q	COG3653 N-acyl-D-aspartate D-glutamate deacylase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
CMS1_k127_5760123_5	1248917.ANFX01000040_gene796	4.862e-57	201.0	COG3788@1|root,COG3788@2|Bacteria,1NBHH@1224|Proteobacteria,2UA0K@28211|Alphaproteobacteria,2K7W6@204457|Sphingomonadales	204457|Sphingomonadales	S	MAPEG family	-	-	-	-	-	-	-	-	-	-	-	-	MAPEG
CMS1_k127_5760123_1	1545915.JROG01000016_gene100	8.775e-244	760.0	COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,2TRIJ@28211|Alphaproteobacteria,2K0Q1@204457|Sphingomonadales	204457|Sphingomonadales	G	phosphomannomutase	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
CMS1_k127_5760123_6	1192759.AKIB01000050_gene1005	2.793e-14	78.0	COG2214@1|root,COG2214@2|Bacteria,1Q626@1224|Proteobacteria,2VCAT@28211|Alphaproteobacteria,2K76N@204457|Sphingomonadales	204457|Sphingomonadales	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
CMS1_k127_5760123_2	1545915.JROG01000007_gene3083	2.207e-119	390.0	COG1192@1|root,COG1192@2|Bacteria,1MVKR@1224|Proteobacteria,2TRZY@28211|Alphaproteobacteria,2K06A@204457|Sphingomonadales	204457|Sphingomonadales	D	involved in chromosome partitioning	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MipZ
CMS1_k127_5760123_3	1123270.ATUR01000004_gene1506	1.894e-105	348.0	COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,2TS2D@28211|Alphaproteobacteria,2K0S2@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
CMS1_k127_5793905_3	1123270.ATUR01000002_gene2216	1.982e-82	277.0	COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,2TT3I@28211|Alphaproteobacteria,2K0XU@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
CMS1_k127_5793905_0	1280941.HY2_12530	7.722e-171	541.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,2TSKV@28211|Alphaproteobacteria,43X72@69657|Hyphomonadaceae	28211|Alphaproteobacteria	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS1_k127_5793905_1	1333998.M2A_1400	2.5e-161	514.0	COG2070@1|root,COG2070@2|Bacteria,1MWPC@1224|Proteobacteria,2TQRT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	2-nitropropane dioxygenase	-	-	1.3.1.9	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	NMO
CMS1_k127_5793905_2	1121949.AQXT01000002_gene1677	2.234e-101	340.0	COG0604@1|root,COG0604@2|Bacteria,1MW2V@1224|Proteobacteria,2U07M@28211|Alphaproteobacteria,43WKG@69657|Hyphomonadaceae	28211|Alphaproteobacteria	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_5798907_1	1248917.ANFX01000019_gene2338	3.315e-173	552.0	COG4638@1|root,COG4638@2|Bacteria,1MXZN@1224|Proteobacteria,2TQRJ@28211|Alphaproteobacteria,2K131@204457|Sphingomonadales	204457|Sphingomonadales	P	Ring hydroxylating alpha subunit (catalytic domain)	-	-	-	-	-	-	-	-	-	-	-	-	Rieske,Ring_hydroxyl_A
CMS1_k127_5798907_4	1545915.JROG01000004_gene1912	1.319e-77	265.0	COG1309@1|root,COG1309@2|Bacteria,1RE97@1224|Proteobacteria,2U8N9@28211|Alphaproteobacteria,2K3XR@204457|Sphingomonadales	204457|Sphingomonadales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS1_k127_5798907_0	317655.Sala_2882	0.0	1234.0	COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,2TTFY@28211|Alphaproteobacteria,2K075@204457|Sphingomonadales	204457|Sphingomonadales	P	receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
CMS1_k127_5798907_3	745310.G432_16310	5.238e-114	374.0	COG0596@1|root,COG0596@2|Bacteria,1MVVX@1224|Proteobacteria,2TT0S@28211|Alphaproteobacteria,2K36R@204457|Sphingomonadales	204457|Sphingomonadales	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS1_k127_5798907_2	1088721.NSU_2248	1.304e-170	543.0	COG2271@1|root,COG2271@2|Bacteria,1MWYR@1224|Proteobacteria,2TSXW@28211|Alphaproteobacteria,2K1KD@204457|Sphingomonadales	204457|Sphingomonadales	G	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_5805966_0	1248760.ANFZ01000013_gene1862	7.156e-127	413.0	COG4166@1|root,COG4166@2|Bacteria,1P91R@1224|Proteobacteria,2TT6P@28211|Alphaproteobacteria,2K3F6@204457|Sphingomonadales	204457|Sphingomonadales	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
CMS1_k127_5805966_1	1248760.ANFZ01000013_gene1861	3.248e-101	347.0	COG4166@1|root,COG4166@2|Bacteria,1P91R@1224|Proteobacteria,2TT6P@28211|Alphaproteobacteria,2K08U@204457|Sphingomonadales	204457|Sphingomonadales	E	ABC-type oligopeptide transport system, periplasmic component	-	-	-	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
CMS1_k127_5805966_2	1207055.C100_01235	5.531e-58	203.0	2DMJE@1|root,32RYR@2|Bacteria,1N7PS@1224|Proteobacteria,2UFEW@28211|Alphaproteobacteria,2K57K@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF4112)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4112
CMS1_k127_5808818_2	1120705.FG95_00626	6.648e-82	277.0	COG2199@1|root,COG2199@2|Bacteria,1R49V@1224|Proteobacteria,2TTDC@28211|Alphaproteobacteria,2K4KD@204457|Sphingomonadales	204457|Sphingomonadales	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
CMS1_k127_5808818_3	517722.AEUE01000004_gene1125	1.483e-74	256.0	COG4566@1|root,COG4566@2|Bacteria,1QYNR@1224|Proteobacteria,2TXT5@28211|Alphaproteobacteria,2K3P9@204457|Sphingomonadales	204457|Sphingomonadales	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,PAS_9
CMS1_k127_5808818_0	1248760.ANFZ01000009_gene1302	1.348e-146	474.0	COG0299@1|root,COG3801@1|root,COG0299@2|Bacteria,COG3801@2|Bacteria,1MWN1@1224|Proteobacteria,2TRY6@28211|Alphaproteobacteria,2K28Q@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N,YjbR
CMS1_k127_5808818_1	702113.PP1Y_AT20499	1.283e-92	307.0	COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,2TR6G@28211|Alphaproteobacteria,2K07H@204457|Sphingomonadales	204457|Sphingomonadales	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
CMS1_k127_5838036_1	1123269.NX02_26080	1.887e-73	258.0	COG5316@1|root,COG5316@2|Bacteria,1MXED@1224|Proteobacteria,2U1NI@28211|Alphaproteobacteria,2K0YR@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5838036_3	1174684.EBMC1_05674	2.303e-49	180.0	COG1607@1|root,COG1607@2|Bacteria,1MZAZ@1224|Proteobacteria,2U93J@28211|Alphaproteobacteria,2K591@204457|Sphingomonadales	204457|Sphingomonadales	I	Acyl-CoA hydrolase	-	-	-	ko:K10806	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT
CMS1_k127_5838036_5	1123270.ATUR01000005_gene414	1.099e-28	118.0	2ACU7@1|root,312F7@2|Bacteria,1N510@1224|Proteobacteria,2UDTR@28211|Alphaproteobacteria,2K6VE@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5838036_4	1449076.JOOE01000004_gene624	1.613e-48	177.0	COG0517@1|root,COG0517@2|Bacteria,1N0H3@1224|Proteobacteria,2UC0F@28211|Alphaproteobacteria,2K5EC@204457|Sphingomonadales	204457|Sphingomonadales	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
CMS1_k127_5838036_2	1219035.NT2_07_00040	1.044e-61	222.0	COG1082@1|root,COG1082@2|Bacteria,1RI1Y@1224|Proteobacteria,2UCVK@28211|Alphaproteobacteria,2K4VU@204457|Sphingomonadales	204457|Sphingomonadales	G	Xylose isomerase	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS1_k127_5838036_0	1123270.ATUR01000005_gene412	6.76e-152	490.0	COG2244@1|root,COG2244@2|Bacteria,1R9I0@1224|Proteobacteria,2TV6V@28211|Alphaproteobacteria,2KD90@204457|Sphingomonadales	204457|Sphingomonadales	S	Membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_3,Polysacc_synt_C
CMS1_k127_5845455_1	1174684.EBMC1_04214	9.137e-55	196.0	COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,2TS5N@28211|Alphaproteobacteria,2K18R@204457|Sphingomonadales	204457|Sphingomonadales	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
CMS1_k127_5845455_0	1123270.ATUR01000004_gene1725	0.0	1029.0	COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,2TRBQ@28211|Alphaproteobacteria,2K1J3@204457|Sphingomonadales	204457|Sphingomonadales	C	E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
CMS1_k127_5863236_7	1545915.JROG01000004_gene1751	1.637e-12	68.0	COG2114@1|root,COG2114@2|Bacteria,1QWNC@1224|Proteobacteria,2TRQB@28211|Alphaproteobacteria,2K2IP@204457|Sphingomonadales	204457|Sphingomonadales	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
CMS1_k127_5863236_2	1168065.DOK_11526	6.602e-113	368.0	COG0695@1|root,COG0695@2|Bacteria,1MXQW@1224|Proteobacteria,1RNAJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Glutaredoxin	grxC	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin,MauE
CMS1_k127_5863236_3	983545.Glaag_4450	4.125e-68	235.0	COG3544@1|root,COG3544@2|Bacteria,1MVU8@1224|Proteobacteria,1RS42@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF305
CMS1_k127_5863236_0	1192759.AKIB01000064_gene3403	0.0	1146.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2TR80@28211|Alphaproteobacteria,2K0EB@204457|Sphingomonadales	204457|Sphingomonadales	P	P-type ATPase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase,YHS
CMS1_k127_5863236_8	1217715.F994_00695	5.765e-08	59.0	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,1RQ4N@1236|Gammaproteobacteria,3NJ08@468|Moraxellaceae	1236|Gammaproteobacteria	Q	Multicopper oxidase	pcoA	-	-	-	-	-	-	-	-	-	-	-	CopB,Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
CMS1_k127_5863236_4	1123270.ATUR01000009_gene1994	4.26e-55	196.0	COG3019@1|root,COG3019@2|Bacteria,1MZ9V@1224|Proteobacteria,2UC0B@28211|Alphaproteobacteria,2K51D@204457|Sphingomonadales	204457|Sphingomonadales	S	metal-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF411
CMS1_k127_5863236_6	1545915.JROG01000001_gene298	8.36e-36	139.0	COG1937@1|root,COG1937@2|Bacteria,1N9P2@1224|Proteobacteria,2UF3F@28211|Alphaproteobacteria,2K5XS@204457|Sphingomonadales	204457|Sphingomonadales	S	Metal-sensitive transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	Trns_repr_metal
CMS1_k127_5863236_1	1234595.C725_1859	6.54e-255	799.0	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,2TQXH@28211|Alphaproteobacteria,4BQU5@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
CMS1_k127_5863236_5	1088721.NSU_2561	2.905e-40	154.0	COG3667@1|root,COG3667@2|Bacteria,1MXW6@1224|Proteobacteria,2U363@28211|Alphaproteobacteria,2K0JZ@204457|Sphingomonadales	204457|Sphingomonadales	P	Copper resistance	-	-	-	ko:K07233	-	-	-	-	ko00000	-	-	-	CopB
CMS1_k127_5872895_19	1545915.JROG01000007_gene3021	1.739e-24	106.0	COG2267@1|root,COG2267@2|Bacteria,1QUNU@1224|Proteobacteria,2TW29@28211|Alphaproteobacteria,2K09G@204457|Sphingomonadales	204457|Sphingomonadales	I	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS1_k127_5872895_14	685035.ADAE01000024_gene1857	9.154e-64	226.0	COG3791@1|root,COG3791@2|Bacteria,1N0W7@1224|Proteobacteria,2VAN9@28211|Alphaproteobacteria,2K7PR@204457|Sphingomonadales	204457|Sphingomonadales	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
CMS1_k127_5872895_10	1545915.JROG01000007_gene3022	1.596e-97	323.0	COG3917@1|root,COG3917@2|Bacteria,1MV6E@1224|Proteobacteria,2TVJ4@28211|Alphaproteobacteria,2K0YH@204457|Sphingomonadales	204457|Sphingomonadales	Q	2-hydroxychromene-2-carboxylate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
CMS1_k127_5872895_18	1174684.EBMC1_05784	3.764e-44	168.0	COG1846@1|root,COG1846@2|Bacteria,1MZY5@1224|Proteobacteria,2U9EE@28211|Alphaproteobacteria,2K62J@204457|Sphingomonadales	204457|Sphingomonadales	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
CMS1_k127_5872895_6	1449076.JOOE01000002_gene878	3.873e-127	419.0	COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,2TS39@28211|Alphaproteobacteria,2K1WC@204457|Sphingomonadales	204457|Sphingomonadales	V	Secretion protein, HlyD	-	-	-	ko:K03543	-	M00701	-	-	ko00000,ko00002,ko02000	8.A.1.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
CMS1_k127_5872895_1	1502850.FG91_01466	4.387e-215	679.0	COG0477@1|root,COG2814@2|Bacteria,1MU1I@1224|Proteobacteria,2TVXT@28211|Alphaproteobacteria,2JZYF@204457|Sphingomonadales	204457|Sphingomonadales	EGP	Major facilitator superfamily	-	-	-	ko:K03446	-	M00701	-	-	ko00000,ko00002,ko02000	2.A.1.3	-	-	MFS_1
CMS1_k127_5872895_3	383381.EH30_07320	6.618e-195	612.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,2TSRD@28211|Alphaproteobacteria,2K104@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
CMS1_k127_5872895_15	1248760.ANFZ01000006_gene2497	1.08e-61	214.0	COG0335@1|root,COG0335@2|Bacteria,1RH3A@1224|Proteobacteria,2U9DF@28211|Alphaproteobacteria,2K4GC@204457|Sphingomonadales	204457|Sphingomonadales	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
CMS1_k127_5872895_9	629773.AORY01000011_gene1753	3.127e-110	364.0	COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,2TSIZ@28211|Alphaproteobacteria,2JZVZ@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
CMS1_k127_5872895_17	1248760.ANFZ01000006_gene2493	2.165e-55	198.0	COG0806@1|root,COG0806@2|Bacteria,1MWQR@1224|Proteobacteria,2U9UT@28211|Alphaproteobacteria,2K4H2@204457|Sphingomonadales	204457|Sphingomonadales	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
CMS1_k127_5872895_16	1044.EH31_03180	1.1e-56	202.0	COG0228@1|root,COG0228@2|Bacteria,1MZCT@1224|Proteobacteria,2U94X@28211|Alphaproteobacteria,2K4I6@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
CMS1_k127_5872895_0	1123270.ATUR01000006_gene24	6.723e-231	722.0	COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,2TQSW@28211|Alphaproteobacteria,2K1DQ@204457|Sphingomonadales	204457|Sphingomonadales	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
CMS1_k127_5872895_2	1030157.AFMP01000042_gene1286	1.58e-202	645.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2U05U@28211|Alphaproteobacteria,2K1IQ@204457|Sphingomonadales	204457|Sphingomonadales	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
CMS1_k127_5872895_8	1545915.JROG01000007_gene3035	5.168e-115	377.0	COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,2TUF2@28211|Alphaproteobacteria,2K1PV@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
CMS1_k127_5872895_4	745310.G432_03105	1.341e-172	556.0	COG0621@1|root,COG0621@2|Bacteria,1MUCS@1224|Proteobacteria,2TRYD@28211|Alphaproteobacteria,2K0WZ@204457|Sphingomonadales	204457|Sphingomonadales	J	2-methylthioadenine	-	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
CMS1_k127_5872895_5	1123270.ATUR01000006_gene20	3.081e-148	475.0	COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,2TS0M@28211|Alphaproteobacteria,2K03J@204457|Sphingomonadales	204457|Sphingomonadales	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
CMS1_k127_5872895_13	1123270.ATUR01000006_gene19	6.824e-80	275.0	COG2917@1|root,COG2917@2|Bacteria,1NWIZ@1224|Proteobacteria,2U74X@28211|Alphaproteobacteria,2K4N8@204457|Sphingomonadales	204457|Sphingomonadales	D	probably involved in intracellular septation	ispZ	-	-	ko:K06190	-	-	-	-	ko00000	-	-	-	IspA
CMS1_k127_5872895_11	1123270.ATUR01000006_gene18	2.977e-96	319.0	COG0605@1|root,COG0605@2|Bacteria,1MVW2@1224|Proteobacteria,2TU3T@28211|Alphaproteobacteria,2K112@204457|Sphingomonadales	204457|Sphingomonadales	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
CMS1_k127_5872895_12	452662.SJA_C1-27540	5.656e-84	282.0	COG3748@1|root,COG3748@2|Bacteria,1RFIZ@1224|Proteobacteria,2U7B1@28211|Alphaproteobacteria,2K410@204457|Sphingomonadales	204457|Sphingomonadales	S	Urate oxidase N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Urate_ox_N
CMS1_k127_5872895_7	1545915.JROG01000003_gene684	7.616e-120	389.0	COG3829@1|root,COG3829@2|Bacteria,1QUPP@1224|Proteobacteria,2TR58@28211|Alphaproteobacteria,2K0CK@204457|Sphingomonadales	204457|Sphingomonadales	K	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain	pspF	-	-	ko:K03974	-	-	-	-	ko00000,ko03000	-	-	-	HTH_8,Sigma54_activat
CMS1_k127_5882428_5	314225.ELI_00375	7.943e-32	126.0	COG0534@1|root,COG0534@2|Bacteria,1MVRV@1224|Proteobacteria,2TS4Z@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	COG0534 Na -driven multidrug efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	MatE
CMS1_k127_5882428_0	1385517.N800_01225	6.22e-180	578.0	COG1760@1|root,COG1760@2|Bacteria,1MUZN@1224|Proteobacteria,1RMJZ@1236|Gammaproteobacteria,1X3P1@135614|Xanthomonadales	135614|Xanthomonadales	E	Serine dehydratase	sdaA	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha,SDH_beta
CMS1_k127_5882428_3	1248760.ANFZ01000009_gene1225	3.741e-117	387.0	COG1234@1|root,COG1234@2|Bacteria,1R64Z@1224|Proteobacteria,2U0BA@28211|Alphaproteobacteria,2K2ZH@204457|Sphingomonadales	204457|Sphingomonadales	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
CMS1_k127_5882428_1	1219035.NT2_07_00510	1.255e-132	431.0	COG2130@1|root,COG2130@2|Bacteria,1MZ3F@1224|Proteobacteria,2U37Z@28211|Alphaproteobacteria,2K157@204457|Sphingomonadales	204457|Sphingomonadales	S	N-terminal domain of oxidoreductase	-	-	-	ko:K07119	-	-	-	-	ko00000	-	-	-	ADH_N_2,ADH_zinc_N
CMS1_k127_5882428_2	1282876.BAOK01000001_gene1581	1.083e-120	399.0	COG0477@1|root,COG2814@2|Bacteria,1MVVW@1224|Proteobacteria,2TVQU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_5882428_4	1248760.ANFZ01000009_gene1224	2.056e-77	267.0	COG0693@1|root,COG0693@2|Bacteria,1N8N6@1224|Proteobacteria,2TT0U@28211|Alphaproteobacteria,2K3CF@204457|Sphingomonadales	204457|Sphingomonadales	S	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
CMS1_k127_5882428_6	1123270.ATUR01000008_gene325	9.587e-08	64.0	COG0810@1|root,COG0810@2|Bacteria,1NB5F@1224|Proteobacteria,2USI1@28211|Alphaproteobacteria,2K2ZM@204457|Sphingomonadales	204457|Sphingomonadales	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
CMS1_k127_5890605_6	1220535.IMCC14465_09480	7.393e-19	86.0	COG1028@1|root,COG1028@2|Bacteria,1NB6S@1224|Proteobacteria,2U1XH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS1_k127_5890605_2	314225.ELI_03575	5.083e-45	165.0	COG3011@1|root,COG3011@2|Bacteria,1Q3II@1224|Proteobacteria,2UFWG@28211|Alphaproteobacteria,2K6D2@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function, DUF393	-	-	-	-	-	-	-	-	-	-	-	-	DUF393
CMS1_k127_5890605_0	1207055.C100_14190	0.0	1300.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,2TRBK@28211|Alphaproteobacteria,2K0E4@204457|Sphingomonadales	204457|Sphingomonadales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
CMS1_k127_5890605_3	317655.Sala_1083	1.318e-39	152.0	COG2050@1|root,COG2050@2|Bacteria,1PP3J@1224|Proteobacteria,2U5E4@28211|Alphaproteobacteria,2K6UX@204457|Sphingomonadales	204457|Sphingomonadales	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
CMS1_k127_5890605_5	1545915.JROG01000003_gene979	1.455e-32	135.0	2A43I@1|root,30SNK@2|Bacteria,1NVI7@1224|Proteobacteria,2URMC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5890605_1	1280953.HOC_11957	2.776e-174	557.0	COG1835@1|root,COG1835@2|Bacteria,1R4CU@1224|Proteobacteria,2U2AF@28211|Alphaproteobacteria,43WPC@69657|Hyphomonadaceae	28211|Alphaproteobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
CMS1_k127_5890605_4	1280954.HPO_12728	3.472e-39	154.0	COG3279@1|root,COG3279@2|Bacteria,1R90R@1224|Proteobacteria,2UAG2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	KT	COG3279 Response regulator of the LytR AlgR family	-	-	-	-	-	-	-	-	-	-	-	-	LytTR
CMS1_k127_5912759_13	1248760.ANFZ01000006_gene2520	1.71e-79	267.0	COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,2TR89@28211|Alphaproteobacteria,2JZXN@204457|Sphingomonadales	204457|Sphingomonadales	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
CMS1_k127_5912759_6	237727.NAP1_13998	1.739e-136	441.0	COG2070@1|root,COG2070@2|Bacteria,1MWPC@1224|Proteobacteria,2TQRT@28211|Alphaproteobacteria,2K9I3@204457|Sphingomonadales	204457|Sphingomonadales	S	Nitronate monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
CMS1_k127_5912759_4	1248760.ANFZ01000004_gene1966	6.451e-166	526.0	COG2070@1|root,COG2070@2|Bacteria,1MU0U@1224|Proteobacteria,2TS5U@28211|Alphaproteobacteria,2K0V5@204457|Sphingomonadales	204457|Sphingomonadales	S	2-nitropropane dioxygenase	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
CMS1_k127_5912759_1	1545915.JROG01000004_gene2419	6.216e-280	870.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,2TSCJ@28211|Alphaproteobacteria,2K1S1@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
CMS1_k127_5912759_17	1522072.IL54_2103	1.929e-15	82.0	COG2114@1|root,COG2114@2|Bacteria,1QVUZ@1224|Proteobacteria,2TZF8@28211|Alphaproteobacteria,2KESR@204457|Sphingomonadales	204457|Sphingomonadales	T	Sensors of blue-light using FAD	-	-	-	-	-	-	-	-	-	-	-	-	BLUF
CMS1_k127_5912759_2	1112214.AHIS01000087_gene458	3.355e-202	632.0	COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,2TRXI@28211|Alphaproteobacteria,2JZWR@204457|Sphingomonadales	204457|Sphingomonadales	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
CMS1_k127_5912759_14	1144307.PMI04_01202	3.591e-75	259.0	COG0440@1|root,COG0440@2|Bacteria,1RAGN@1224|Proteobacteria,2U5CW@28211|Alphaproteobacteria,2K12R@204457|Sphingomonadales	204457|Sphingomonadales	E	acetolactate synthase	ilvH	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
CMS1_k127_5912759_0	627192.SLG_20710	1.718e-299	927.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2TR1I@28211|Alphaproteobacteria,2K0GG@204457|Sphingomonadales	204457|Sphingomonadales	EH	COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS1_k127_5912759_9	1335760.ASTG01000009_gene264	2.656e-107	357.0	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,2TR8Z@28211|Alphaproteobacteria,2K0WU@204457|Sphingomonadales	204457|Sphingomonadales	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
CMS1_k127_5912759_12	194867.ALBQ01000042_gene1322	3.763e-88	301.0	COG0560@1|root,COG0560@2|Bacteria,1MWA3@1224|Proteobacteria,2TSEU@28211|Alphaproteobacteria,2K069@204457|Sphingomonadales	204457|Sphingomonadales	E	phosphoserine phosphatase	serB	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	HAD
CMS1_k127_5912759_10	1248760.ANFZ01000013_gene1842	8.132e-105	352.0	COG0790@1|root,COG0790@2|Bacteria,1RJ71@1224|Proteobacteria,2U15P@28211|Alphaproteobacteria,2K032@204457|Sphingomonadales	204457|Sphingomonadales	S	FOG TPR repeat, SEL1 subfamily	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	SPOR,Sel1
CMS1_k127_5912759_7	1044.EH31_09265	6.096e-129	414.0	COG1192@1|root,COG1192@2|Bacteria,1MWH3@1224|Proteobacteria,2U100@28211|Alphaproteobacteria,2K0JR@204457|Sphingomonadales	204457|Sphingomonadales	D	involved in chromosome partitioning	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
CMS1_k127_5912759_16	1248760.ANFZ01000013_gene1844	2.272e-33	141.0	2BWQA@1|root,2ZWJK@2|Bacteria,1N8MW@1224|Proteobacteria,2UGCR@28211|Alphaproteobacteria,2K66S@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5912759_11	1123270.ATUR01000002_gene2657	2.016e-92	322.0	COG3087@1|root,COG5010@1|root,COG3087@2|Bacteria,COG5010@2|Bacteria,1RK9P@1224|Proteobacteria,2U5CI@28211|Alphaproteobacteria,2K119@204457|Sphingomonadales	204457|Sphingomonadales	U	Sporulation related domain	-	-	-	-	-	-	-	-	-	-	-	-	SPOR,TPR_16,TPR_19,TPR_4
CMS1_k127_5912759_5	1120705.FG95_00291	1.495e-161	519.0	COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,2TSTM@28211|Alphaproteobacteria,2K003@204457|Sphingomonadales	204457|Sphingomonadales	F	dihydroorotase	-	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
CMS1_k127_5912759_3	1123270.ATUR01000002_gene2659	2.951e-169	536.0	COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,2TRHP@28211|Alphaproteobacteria,2K0IH@204457|Sphingomonadales	204457|Sphingomonadales	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
CMS1_k127_5912759_15	745310.G432_15440	5.561e-56	200.0	COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,2U98Y@28211|Alphaproteobacteria,2K4GA@204457|Sphingomonadales	204457|Sphingomonadales	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
CMS1_k127_5912759_8	1123270.ATUR01000002_gene2662	3.113e-109	357.0	COG2267@1|root,COG2267@2|Bacteria,1MVDA@1224|Proteobacteria,2TUDQ@28211|Alphaproteobacteria,2K1MR@204457|Sphingomonadales	204457|Sphingomonadales	I	Protein of unknown function (DUF3089)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3089
CMS1_k127_5995629_1	1123270.ATUR01000006_gene33	2.197e-91	305.0	COG2267@1|root,COG2267@2|Bacteria,1QUNU@1224|Proteobacteria,2TW29@28211|Alphaproteobacteria,2K09G@204457|Sphingomonadales	204457|Sphingomonadales	I	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS1_k127_5995629_0	1545915.JROG01000007_gene3019	4.027e-321	990.0	COG1164@1|root,COG1164@2|Bacteria,1MWYN@1224|Proteobacteria,2TR6R@28211|Alphaproteobacteria,2K13P@204457|Sphingomonadales	204457|Sphingomonadales	E	Angiotensin-converting enzyme	-	-	3.4.15.1	ko:K01283	ko04614,ko04924,ko05142,ko05410,map04614,map04924,map05142,map05410	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	Peptidase_M2
CMS1_k127_5995629_2	1122970.AUHC01000001_gene856	6.701e-62	214.0	COG0678@1|root,COG0678@2|Bacteria,1MU0H@1224|Proteobacteria,2U6ZN@28211|Alphaproteobacteria,2K3WE@204457|Sphingomonadales	204457|Sphingomonadales	O	Alkyl hydroperoxide reductase	-	-	-	-	-	-	-	-	-	-	-	-	Redoxin
CMS1_k127_6019395_5	573065.Astex_0183	4.768e-33	133.0	COG2311@1|root,COG2311@2|Bacteria,1R7EU@1224|Proteobacteria,2U4AG@28211|Alphaproteobacteria,2KI29@204458|Caulobacterales	204458|Caulobacterales	S	Protein of unknown function (DUF418)	-	-	-	ko:K07148	-	-	-	-	ko00000	-	-	-	DUF418
CMS1_k127_6019395_3	317655.Sala_1055	4.041e-123	405.0	COG2130@1|root,COG2130@2|Bacteria,1MUC2@1224|Proteobacteria,2TQYM@28211|Alphaproteobacteria,2K21X@204457|Sphingomonadales	204457|Sphingomonadales	L	alcohol dehydrogenase	-	-	-	ko:K07119	-	-	-	-	ko00000	-	-	-	ADH_N_2,ADH_zinc_N
CMS1_k127_6019395_6	1122970.AUHC01000011_gene2746	1.781e-15	79.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,2TQR5@28211|Alphaproteobacteria,2K0GD@204457|Sphingomonadales	204457|Sphingomonadales	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
CMS1_k127_6019395_1	1174684.EBMC1_03130	3.934e-146	466.0	COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,2TQTH@28211|Alphaproteobacteria,2K0AR@204457|Sphingomonadales	204457|Sphingomonadales	E	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
CMS1_k127_6019395_0	930166.CD58_10465	1.878e-162	530.0	COG2194@1|root,COG2194@2|Bacteria	2|Bacteria	T	sulfuric ester hydrolase activity	-	-	2.7.8.43	ko:K03760,ko:K19353	ko00540,ko01503,map00540,map01503	M00722	R11555,R11556,R11557	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DUF1499,DUF1705,Sulfatase
CMS1_k127_6019395_2	1123270.ATUR01000004_gene1616	8.588e-127	414.0	COG1058@1|root,COG1058@2|Bacteria,1MVG6@1224|Proteobacteria,2TU5C@28211|Alphaproteobacteria,2K05Q@204457|Sphingomonadales	204457|Sphingomonadales	S	nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
CMS1_k127_6019395_4	1443111.JASG01000004_gene972	5.226e-49	178.0	2E4J2@1|root,32XFY@2|Bacteria,1Q48T@1224|Proteobacteria,2UCU5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3775)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3775
CMS1_k127_6021777_2	1248760.ANFZ01000011_gene336	1.428e-50	188.0	29C68@1|root,2ZZ63@2|Bacteria,1N4ZZ@1224|Proteobacteria,2UCZ8@28211|Alphaproteobacteria,2K5XA@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_6021777_0	1174684.EBMC1_05584	9.697e-191	608.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,2TQRC@28211|Alphaproteobacteria,2K1Y8@204457|Sphingomonadales	204457|Sphingomonadales	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
CMS1_k127_6021777_1	1248916.ANFY01000003_gene503	4.914e-181	571.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,2TR4P@28211|Alphaproteobacteria,2K02E@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
CMS1_k127_6029509_3	1429916.X566_16725	3.112e-111	360.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2TQQ7@28211|Alphaproteobacteria,3JR1V@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Belongs to the thiolase family	MA20_05130	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
CMS1_k127_6029509_1	1502850.FG91_02855	8.132e-122	398.0	COG1946@1|root,COG1946@2|Bacteria,1MV9R@1224|Proteobacteria,2TRFD@28211|Alphaproteobacteria,2K289@204457|Sphingomonadales	204457|Sphingomonadales	I	Acyl-CoA thioesterase	-	-	-	ko:K10805	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT_3
CMS1_k127_6029509_0	314225.ELI_00310	2.372e-278	865.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,2JZZB@204457|Sphingomonadales	204457|Sphingomonadales	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
CMS1_k127_6029509_2	517722.AEUE01000001_gene2681	4.608e-115	372.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2TS8E@28211|Alphaproteobacteria,2K0RP@204457|Sphingomonadales	204457|Sphingomonadales	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
CMS1_k127_6048063_7	1090319.KE386571_gene2512	2.67e-49	176.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,2TR4P@28211|Alphaproteobacteria,2K02E@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
CMS1_k127_6048063_2	627192.SLG_33260	1.809e-123	398.0	COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,2TUU9@28211|Alphaproteobacteria,2K0BM@204457|Sphingomonadales	204457|Sphingomonadales	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	-	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
CMS1_k127_6048063_3	1090319.KE386571_gene221	4.383e-89	304.0	COG3687@1|root,COG3687@2|Bacteria,1MWGV@1224|Proteobacteria,2U1DK@28211|Alphaproteobacteria,2K0CB@204457|Sphingomonadales	204457|Sphingomonadales	S	Predicted metal-dependent hydrolase	-	-	-	ko:K07044	-	-	-	-	ko00000	-	-	-	Metal_hydrol
CMS1_k127_6048063_6	1537715.JQFJ01000002_gene2287	4.883e-59	209.0	COG1670@1|root,COG1670@2|Bacteria,1N6Q1@1224|Proteobacteria,2UG72@28211|Alphaproteobacteria,2K4XG@204457|Sphingomonadales	204457|Sphingomonadales	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
CMS1_k127_6048063_9	745310.G432_17315	5.378e-44	160.0	COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,2UBUX@28211|Alphaproteobacteria,2K60H@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
CMS1_k127_6048063_8	1537715.JQFJ01000002_gene2289	6.011e-47	174.0	COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,2UBT3@28211|Alphaproteobacteria,2K5A0@204457|Sphingomonadales	204457|Sphingomonadales	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
CMS1_k127_6048063_10	1174684.EBMC1_03575	1.103e-18	95.0	2ANQF@1|root,31DQ1@2|Bacteria,1NB6K@1224|Proteobacteria,2UH5D@28211|Alphaproteobacteria,2K6TZ@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_6048063_11	314266.SKA58_15037	1.192e-15	80.0	28YKP@1|root,2ZKEE@2|Bacteria,1NBD7@1224|Proteobacteria,2UHHD@28211|Alphaproteobacteria,2K531@204457|Sphingomonadales	204457|Sphingomonadales	S	Pilus assembly protein PilZ	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
CMS1_k127_6048063_4	1248760.ANFZ01000006_gene2458	9.701e-85	284.0	COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,2U5GR@28211|Alphaproteobacteria,2K4AW@204457|Sphingomonadales	204457|Sphingomonadales	S	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
CMS1_k127_6048063_5	1096930.L284_15175	4.375e-59	210.0	COG1670@1|root,COG1670@2|Bacteria,1RCX2@1224|Proteobacteria,2U97G@28211|Alphaproteobacteria,2K59G@204457|Sphingomonadales	204457|Sphingomonadales	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
CMS1_k127_6048063_1	702113.PP1Y_AT257	1.178e-167	531.0	COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,2TS3F@28211|Alphaproteobacteria,2K011@204457|Sphingomonadales	204457|Sphingomonadales	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
CMS1_k127_6048063_0	1123270.ATUR01000002_gene2270	7.45e-186	591.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2TT3Z@28211|Alphaproteobacteria,2K2A0@204457|Sphingomonadales	204457|Sphingomonadales	M	membrane	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CMS1_k127_6088226_15	1168065.DOK_02661	1.903e-69	238.0	COG3670@1|root,COG3670@2|Bacteria,1MY1X@1224|Proteobacteria,1RRE0@1236|Gammaproteobacteria,1J882@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Retinal pigment epithelial membrane protein	-	-	-	ko:K11159	-	-	-	-	ko00000	-	-	-	RPE65
CMS1_k127_6088226_5	1549858.MC45_13765	2.893e-183	577.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,2TQNG@28211|Alphaproteobacteria,2K0Y3@204457|Sphingomonadales	204457|Sphingomonadales	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
CMS1_k127_6088226_11	1545915.JROG01000001_gene351	9.612e-75	256.0	COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,2TSKM@28211|Alphaproteobacteria,2K2JA@204457|Sphingomonadales	204457|Sphingomonadales	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
CMS1_k127_6088226_12	1522072.IL54_0923	1.244e-73	250.0	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,2U70Z@28211|Alphaproteobacteria,2K4Q1@204457|Sphingomonadales	204457|Sphingomonadales	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
CMS1_k127_6088226_19	279238.Saro_0420	1.209e-42	159.0	2B9KW@1|root,322Z5@2|Bacteria,1RJJB@1224|Proteobacteria,2UAVD@28211|Alphaproteobacteria,2K6EC@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_6088226_9	1545915.JROG01000001_gene353	1.878e-120	390.0	COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,2TRSK@28211|Alphaproteobacteria,2K0KW@204457|Sphingomonadales	204457|Sphingomonadales	K	transcriptional regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
CMS1_k127_6088226_22	237727.NAP1_11673	8.919e-18	98.0	COG1266@1|root,COG1266@2|Bacteria,1NN54@1224|Proteobacteria,2UUZE@28211|Alphaproteobacteria,2K77V@204457|Sphingomonadales	204457|Sphingomonadales	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
CMS1_k127_6088226_17	702113.PP1Y_AT35196	6.949e-46	168.0	COG0393@1|root,COG0393@2|Bacteria,1N0XM@1224|Proteobacteria,2UCR7@28211|Alphaproteobacteria,2K5MQ@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the UPF0145 family	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
CMS1_k127_6088226_16	1346791.M529_13325	4.925e-68	234.0	COG1247@1|root,COG1247@2|Bacteria,1RDHN@1224|Proteobacteria,2U98I@28211|Alphaproteobacteria,2K490@204457|Sphingomonadales	204457|Sphingomonadales	M	Acetyltransferase (GNAT) domain	-	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
CMS1_k127_6088226_20	314266.SKA58_12607	1.391e-33	131.0	COG3750@1|root,COG3750@2|Bacteria,1N77J@1224|Proteobacteria,2UFX6@28211|Alphaproteobacteria,2K5Z1@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the UPF0335 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF2312
CMS1_k127_6088226_21	1234595.C725_1070	5.569e-30	121.0	COG3492@1|root,COG3492@2|Bacteria,1MZ3I@1224|Proteobacteria,2UC11@28211|Alphaproteobacteria,4BQI0@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1244)	MA20_03865	-	-	ko:K09948	-	-	-	-	ko00000	-	-	-	DUF1244
CMS1_k127_6088226_4	745310.G432_11905	6.27e-209	659.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,2TRFV@28211|Alphaproteobacteria,2K07D@204457|Sphingomonadales	204457|Sphingomonadales	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
CMS1_k127_6088226_13	1123270.ATUR01000004_gene1696	5.634e-73	252.0	COG1011@1|root,COG1011@2|Bacteria,1RHAB@1224|Proteobacteria,2U7PV@28211|Alphaproteobacteria,2K2XU@204457|Sphingomonadales	204457|Sphingomonadales	S	Hydrolase	-	-	3.8.1.2	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
CMS1_k127_6088226_23	314225.ELI_10925	1.029e-16	79.0	COG0257@1|root,COG0257@2|Bacteria,1NGBJ@1224|Proteobacteria	1224|Proteobacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
CMS1_k127_6088226_6	13689.BV96_03953	1.218e-177	560.0	COG1087@1|root,COG1087@2|Bacteria,1MUHI@1224|Proteobacteria,2TTC7@28211|Alphaproteobacteria,2K1G3@204457|Sphingomonadales	204457|Sphingomonadales	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
CMS1_k127_6088226_18	1174684.EBMC1_06154	8.673e-45	172.0	2C2VU@1|root,34305@2|Bacteria,1N3B4@1224|Proteobacteria,2UCFR@28211|Alphaproteobacteria,2K63E@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4136
CMS1_k127_6088226_7	1248760.ANFZ01000006_gene2675	6.34e-172	556.0	COG2866@1|root,COG2866@2|Bacteria,1MUMN@1224|Proteobacteria,2TREN@28211|Alphaproteobacteria,2K01Q@204457|Sphingomonadales	204457|Sphingomonadales	E	Carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
CMS1_k127_6088226_1	1174684.EBMC1_00575	1.033e-288	894.0	COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,2TRAP@28211|Alphaproteobacteria,2K0IY@204457|Sphingomonadales	204457|Sphingomonadales	EGP	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
CMS1_k127_6088226_8	1120705.FG95_00428	1.122e-130	423.0	COG1309@1|root,COG1309@2|Bacteria,1R6X5@1224|Proteobacteria,2U7EK@28211|Alphaproteobacteria,2K2FW@204457|Sphingomonadales	204457|Sphingomonadales	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS1_k127_6088226_3	1120705.FG95_00429	7.324e-275	857.0	COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,2TR96@28211|Alphaproteobacteria,2K0TE@204457|Sphingomonadales	204457|Sphingomonadales	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	6.2.1.44	ko:K20034	ko00920,map00920	-	R10820	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
CMS1_k127_6088226_2	1120705.FG95_00430	2.774e-284	882.0	COG2272@1|root,COG2272@2|Bacteria,1MVQZ@1224|Proteobacteria,2TUA9@28211|Alphaproteobacteria,2K1A5@204457|Sphingomonadales	204457|Sphingomonadales	I	Belongs to the type-B carboxylesterase lipase family	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase,PBP
CMS1_k127_6088226_0	1120705.FG95_00431	0.0	1333.0	COG4773@1|root,COG4773@2|Bacteria,1QURT@1224|Proteobacteria,2TW53@28211|Alphaproteobacteria,2K0HG@204457|Sphingomonadales	204457|Sphingomonadales	P	receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
CMS1_k127_6088226_10	1096930.L284_04235	6.945e-90	308.0	COG0438@1|root,COG0438@2|Bacteria,1RBPW@1224|Proteobacteria,2U6IH@28211|Alphaproteobacteria,2K4BB@204457|Sphingomonadales	204457|Sphingomonadales	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
CMS1_k127_6088226_14	935557.ATYB01000008_gene5221	1.386e-71	250.0	2DG8R@1|root,2ZUYV@2|Bacteria,1RG4Q@1224|Proteobacteria,2U6V3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Sulfotransferase domain	-	-	2.8.2.2	ko:K01015	ko00140,map00140	-	R00629,R03405,R08977,R08978	RC00007,RC00231,RC00341	ko00000,ko00001,ko01000	-	-	-	Sulfotransfer_1
CMS1_k127_6094429_8	1537715.JQFJ01000002_gene1556	7.113e-54	190.0	COG1236@1|root,COG1236@2|Bacteria,1MV7U@1224|Proteobacteria,2TQU5@28211|Alphaproteobacteria,2K1G9@204457|Sphingomonadales	204457|Sphingomonadales	J	exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	ko:K07577	-	-	-	-	ko00000	-	-	-	Lactamase_B
CMS1_k127_6094429_0	1502850.FG91_03892	9.184e-254	796.0	COG1793@1|root,COG1793@2|Bacteria,1MV3S@1224|Proteobacteria,2TRQ9@28211|Alphaproteobacteria,2K08Z@204457|Sphingomonadales	204457|Sphingomonadales	L	ATP-dependent DNA ligase	-	-	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
CMS1_k127_6094429_3	1248917.ANFX01000008_gene322	2.228e-123	410.0	COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,2TSJ5@28211|Alphaproteobacteria,2K2R1@204457|Sphingomonadales	204457|Sphingomonadales	P	Ring hydroxylating alpha subunit (catalytic domain)	-	-	-	-	-	-	-	-	-	-	-	-	Rieske,Ring_hydroxyl_A
CMS1_k127_6094429_6	46429.BV95_00225	2.536e-71	246.0	COG3038@1|root,COG3038@2|Bacteria,1MZ7X@1224|Proteobacteria,2UBYU@28211|Alphaproteobacteria,2K56E@204457|Sphingomonadales	204457|Sphingomonadales	C	Prokaryotic cytochrome b561	-	-	-	ko:K12262	-	-	-	-	ko00000	-	-	-	Ni_hydr_CYTB
CMS1_k127_6094429_2	395964.KE386496_gene1239	1.891e-127	421.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,2TRTJ@28211|Alphaproteobacteria,3NBD5@45404|Beijerinckiaceae	28211|Alphaproteobacteria	P	PFAM Di-haem cytochrome c peroxidase	ccpA	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
CMS1_k127_6094429_1	1121949.AQXT01000002_gene1943	1.483e-129	427.0	COG2267@1|root,COG2267@2|Bacteria,1QTAP@1224|Proteobacteria,2TU8W@28211|Alphaproteobacteria,43WM6@69657|Hyphomonadaceae	28211|Alphaproteobacteria	I	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS1_k127_6094429_9	1030157.AFMP01000052_gene189	8.897e-36	140.0	COG0640@1|root,COG0640@2|Bacteria,1MZAU@1224|Proteobacteria,2U9NV@28211|Alphaproteobacteria,2K56X@204457|Sphingomonadales	204457|Sphingomonadales	K	ArsR family transcriptional regulator	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20
CMS1_k127_6094429_7	1120705.FG95_00352	6.904e-65	224.0	COG0346@1|root,COG0346@2|Bacteria,1RHIV@1224|Proteobacteria,2TR4K@28211|Alphaproteobacteria,2K47U@204457|Sphingomonadales	204457|Sphingomonadales	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS1_k127_6094429_5	690585.JNNU01000009_gene693	7.654e-73	254.0	COG0394@1|root,COG0394@2|Bacteria,1MWYQ@1224|Proteobacteria,2TU1U@28211|Alphaproteobacteria,4BBYM@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	HTH_20,LMWPc
CMS1_k127_6094429_4	1381123.AYOD01000011_gene2882	2.112e-111	364.0	COG0798@1|root,COG0798@2|Bacteria,1MUXY@1224|Proteobacteria,2TSVJ@28211|Alphaproteobacteria,43HFQ@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	P	Sodium Bile acid symporter family	-	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
CMS1_k127_6144128_3	1192759.AKIB01000088_gene2228	4.477e-107	357.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,2TR1W@28211|Alphaproteobacteria,2JZYK@204457|Sphingomonadales	204457|Sphingomonadales	FP	exopolyphosphatase	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
CMS1_k127_6144128_2	1090320.KB900605_gene2686	2.284e-182	578.0	COG0349@1|root,COG0349@2|Bacteria,1MURV@1224|Proteobacteria,2TSQM@28211|Alphaproteobacteria,2K0ID@204457|Sphingomonadales	204457|Sphingomonadales	J	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides	rnd	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
CMS1_k127_6144128_5	1248760.ANFZ01000009_gene1290	3.577e-19	91.0	2A3FR@1|root,30RYH@2|Bacteria,1P2M4@1224|Proteobacteria,2UVD9@28211|Alphaproteobacteria,2K882@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_6144128_1	1545915.JROG01000003_gene1090	6.634e-187	596.0	COG0277@1|root,COG0277@2|Bacteria,1RKIM@1224|Proteobacteria,2U9XY@28211|Alphaproteobacteria,2K51V@204457|Sphingomonadales	204457|Sphingomonadales	C	FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_4
CMS1_k127_6144128_4	1380384.JADN01000009_gene177	1.412e-49	188.0	28KH6@1|root,2ZA2R@2|Bacteria,4NI7X@976|Bacteroidetes,1HYH8@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_6144128_0	1044.EH31_00765	0.0	1237.0	COG1913@1|root,COG1913@2|Bacteria,1MY52@1224|Proteobacteria,2TUDY@28211|Alphaproteobacteria,2K1Q2@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF5117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117
CMS1_k127_6144128_7	761193.Runsl_2020	4.352e-10	61.0	COG0715@1|root,COG0715@2|Bacteria,4NH2X@976|Bacteroidetes,47JPM@768503|Cytophagia	976|Bacteroidetes	P	Protein of unknown function (DUF3500)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3500
CMS1_k127_6268455_10	627192.SLG_29720	1.811e-11	66.0	29ZFV@1|root,30MFE@2|Bacteria,1P1QW@1224|Proteobacteria,2UUZS@28211|Alphaproteobacteria,2K7ZD@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_6268455_3	1192759.AKIB01000116_gene3719	1.204e-128	412.0	COG2945@1|root,COG2945@2|Bacteria,1MUDY@1224|Proteobacteria,2TRMI@28211|Alphaproteobacteria,2JZVR@204457|Sphingomonadales	204457|Sphingomonadales	S	Alpha Beta	-	-	-	ko:K07018	-	-	-	-	ko00000	-	-	-	Hydrolase_4,Peptidase_S15
CMS1_k127_6268455_4	1123269.NX02_04950	5.427e-121	398.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,2TSQE@28211|Alphaproteobacteria,2JZZX@204457|Sphingomonadales	204457|Sphingomonadales	E	overlaps another CDS with the same product name	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
CMS1_k127_6268455_2	1248760.ANFZ01000009_gene1404	2.702e-144	467.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,2TSQE@28211|Alphaproteobacteria,2K05P@204457|Sphingomonadales	204457|Sphingomonadales	E	overlaps another CDS with the same product name	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
CMS1_k127_6268455_7	1123270.ATUR01000003_gene1142	2.826e-42	157.0	COG0633@1|root,COG0633@2|Bacteria,1RHDC@1224|Proteobacteria,2U97J@28211|Alphaproteobacteria,2K5X1@204457|Sphingomonadales	204457|Sphingomonadales	C	Ferredoxin	-	-	-	ko:K04755	-	-	-	-	ko00000	-	-	-	Fer2
CMS1_k127_6268455_1	1123270.ATUR01000003_gene1140	1.95e-214	682.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,2TRPB@28211|Alphaproteobacteria,2K0MV@204457|Sphingomonadales	204457|Sphingomonadales	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3,DUF3646
CMS1_k127_6268455_5	517722.AEUE01000004_gene943	1.05e-44	164.0	COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,2UBQB@28211|Alphaproteobacteria,2K5JW@204457|Sphingomonadales	204457|Sphingomonadales	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
CMS1_k127_6268455_0	1144307.PMI04_01458	0.0	1256.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,2TR4E@28211|Alphaproteobacteria,2K15B@204457|Sphingomonadales	204457|Sphingomonadales	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
CMS1_k127_6268455_8	1123270.ATUR01000003_gene1137	2.253e-37	143.0	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,2UC5G@28211|Alphaproteobacteria,2K5WD@204457|Sphingomonadales	204457|Sphingomonadales	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	-	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
CMS1_k127_6268455_9	161528.ED21_18027	3.461e-36	139.0	COG1734@1|root,COG1734@2|Bacteria,1MZIB@1224|Proteobacteria,2UCQA@28211|Alphaproteobacteria,2K69Z@204457|Sphingomonadales	204457|Sphingomonadales	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
CMS1_k127_6268455_6	1280953.HOC_13374	1.212e-42	159.0	COG4773@1|root,COG4773@2|Bacteria,1QTT0@1224|Proteobacteria,2UBE7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
CMS1_k127_636438_2	292564.Cyagr_0351	1.205e-30	128.0	COG3187@1|root,COG3187@2|Bacteria,1GMTF@1117|Cyanobacteria,22TW4@167375|Cyanobium	1117|Cyanobacteria	O	META domain	-	-	-	-	-	-	-	-	-	-	-	-	META
CMS1_k127_636438_1	161528.ED21_31154	1.032e-47	176.0	2EGQ7@1|root,33AGD@2|Bacteria,1NI1N@1224|Proteobacteria,2UJJ3@28211|Alphaproteobacteria,2K5B7@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_636438_0	314225.ELI_01410	3.935e-96	321.0	2DN0U@1|root,32UTB@2|Bacteria,1MZ2J@1224|Proteobacteria,2UHAI@28211|Alphaproteobacteria,2K24S@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_636438_3	745310.G432_03770	1.125e-18	91.0	COG3555@1|root,COG3555@2|Bacteria,1MW3M@1224|Proteobacteria,2U5YV@28211|Alphaproteobacteria,2K07E@204457|Sphingomonadales	204457|Sphingomonadales	O	Aspartyl/Asparaginyl beta-hydroxylase	-	-	-	ko:K12979	-	-	-	-	ko00000,ko01000,ko01005	-	-	-	Asp_Arg_Hydrox
CMS1_k127_653709_9	1030157.AFMP01000062_gene3497	4.187e-19	88.0	COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,2U6ZC@28211|Alphaproteobacteria,2K3WB@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
CMS1_k127_653709_2	452662.SJA_C1-33790	5.052e-173	551.0	COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,2TS83@28211|Alphaproteobacteria,2K0DR@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS1_k127_653709_3	1545915.JROG01000003_gene1582	8.603e-108	361.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2TQZE@28211|Alphaproteobacteria,2K148@204457|Sphingomonadales	204457|Sphingomonadales	M	COG0739 Membrane proteins related to metalloendopeptidases	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CMS1_k127_653709_5	1248760.ANFZ01000024_gene1687	3.18e-33	134.0	COG1664@1|root,COG1664@2|Bacteria,1MZN0@1224|Proteobacteria,2U5DW@28211|Alphaproteobacteria,2K66W@204457|Sphingomonadales	204457|Sphingomonadales	M	Integral membrane protein CcmA involved in cell shape determination	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
CMS1_k127_653709_0	1174684.EBMC1_11635	3.099e-258	804.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,2TQU6@28211|Alphaproteobacteria,2K1A3@204457|Sphingomonadales	204457|Sphingomonadales	O	ATPase with chaperone activity	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
CMS1_k127_653709_4	1537715.JQFJ01000002_gene2363	7.942e-62	222.0	COG3904@1|root,COG3904@2|Bacteria,1RHKD@1224|Proteobacteria,2UAIF@28211|Alphaproteobacteria,2K5UD@204457|Sphingomonadales	204457|Sphingomonadales	S	periplasmic protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_653709_8	1174684.EBMC1_11575	1.1e-19	92.0	2A3CY@1|root,30RVE@2|Bacteria,1NNPQ@1224|Proteobacteria,2UJZN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PGPGW
CMS1_k127_653709_10	1537715.JQFJ01000002_gene2360	2.158e-16	79.0	COG0230@1|root,COG0230@2|Bacteria,1NGGS@1224|Proteobacteria,2UJCE@28211|Alphaproteobacteria,2K753@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
CMS1_k127_653709_7	383381.EH30_11580	3.082e-27	118.0	COG0594@1|root,COG0594@2|Bacteria,1N6QY@1224|Proteobacteria,2UFAB@28211|Alphaproteobacteria,2K5Y4@204457|Sphingomonadales	204457|Sphingomonadales	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
CMS1_k127_653709_6	279238.Saro_0577	1.039e-28	123.0	COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,2UFKH@28211|Alphaproteobacteria,2K6W4@204457|Sphingomonadales	204457|Sphingomonadales	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
CMS1_k127_653709_1	702113.PP1Y_AT33971	1.048e-179	578.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,2TSTJ@28211|Alphaproteobacteria,2K1E1@204457|Sphingomonadales	204457|Sphingomonadales	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
CMS1_k127_679630_39	1114964.L485_01380	0.0003415	46.0	COG1226@1|root,COG1226@2|Bacteria,1MXQP@1224|Proteobacteria,2TTRN@28211|Alphaproteobacteria,2K11P@204457|Sphingomonadales	204457|Sphingomonadales	P	COG1226 Kef-type K transport systems	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_N
CMS1_k127_679630_12	1192759.AKIB01000116_gene3811	3.382e-110	366.0	COG1388@1|root,COG4942@1|root,COG1388@2|Bacteria,COG4942@2|Bacteria,1RD24@1224|Proteobacteria,2TUNI@28211|Alphaproteobacteria,2K0K8@204457|Sphingomonadales	204457|Sphingomonadales	DM	COG0739 Membrane proteins related to metalloendopeptidases	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23
CMS1_k127_679630_11	1550073.JROH01000004_gene2315	1.845e-120	393.0	COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,2TQXZ@28211|Alphaproteobacteria,2K0F4@204457|Sphingomonadales	204457|Sphingomonadales	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
CMS1_k127_679630_3	1088721.NSU_0789	1.052e-200	632.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,2TR4T@28211|Alphaproteobacteria,2K0IX@204457|Sphingomonadales	204457|Sphingomonadales	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
CMS1_k127_679630_32	1470591.BW41_03625	9.213e-32	138.0	29EWP@1|root,301UE@2|Bacteria,1RESF@1224|Proteobacteria,2U90E@28211|Alphaproteobacteria,2K46N@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
CMS1_k127_679630_26	1502850.FG91_00412	8.533e-56	202.0	COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,2U74V@28211|Alphaproteobacteria,2K4GE@204457|Sphingomonadales	204457|Sphingomonadales	T	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
CMS1_k127_679630_33	1123270.ATUR01000008_gene297	4.435e-31	127.0	29W6B@1|root,30HRE@2|Bacteria,1NB66@1224|Proteobacteria,2UGIS@28211|Alphaproteobacteria,2K738@204457|Sphingomonadales	204457|Sphingomonadales	S	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
CMS1_k127_679630_6	1234595.C725_2413	5.946e-167	531.0	COG1804@1|root,COG1804@2|Bacteria,1MW1H@1224|Proteobacteria,2TR7D@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	carnitine dehydratase	-	-	5.1.99.4	ko:K01796	ko00120,ko01100,ko04146,map00120,map01100,map04146	M00104	R08734,R08739	RC02345	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_transf_3
CMS1_k127_679630_30	1112214.AHIS01000050_gene2383	6.766e-50	186.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,2TSPC@28211|Alphaproteobacteria,2KD3G@204457|Sphingomonadales	204457|Sphingomonadales	T	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
CMS1_k127_679630_29	1331060.RLDS_23975	3.379e-51	196.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,2U103@28211|Alphaproteobacteria,2K0W4@204457|Sphingomonadales	204457|Sphingomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
CMS1_k127_679630_8	1123270.ATUR01000010_gene1912	3.587e-140	456.0	2C57D@1|root,2Z7RS@2|Bacteria,1MX6G@1224|Proteobacteria,2TTDU@28211|Alphaproteobacteria,2K0FT@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF2891)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2891
CMS1_k127_679630_9	1545915.JROG01000003_gene1235	1.648e-136	448.0	COG0534@1|root,COG0534@2|Bacteria,1MVRV@1224|Proteobacteria,2TS4Z@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	COG0534 Na -driven multidrug efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	MatE
CMS1_k127_679630_15	1545915.JROG01000003_gene1237	2.637e-91	316.0	COG3773@1|root,COG3773@2|Bacteria,1MWX3@1224|Proteobacteria,2TT15@28211|Alphaproteobacteria,2K0Z3@204457|Sphingomonadales	204457|Sphingomonadales	M	Cell Wall	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_2
CMS1_k127_679630_2	629773.AORY01000001_gene2108	6.181e-250	776.0	COG3200@1|root,COG3200@2|Bacteria,1MUWF@1224|Proteobacteria,2TR0E@28211|Alphaproteobacteria,2K0JX@204457|Sphingomonadales	204457|Sphingomonadales	E	phospho-2-dehydro-3-deoxyheptonate aldolase	aroF	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_2
CMS1_k127_679630_35	1545915.JROG01000004_gene2496	3.218e-18	87.0	2EGKD@1|root,33ACM@2|Bacteria,1NAVJ@1224|Proteobacteria,2UGT0@28211|Alphaproteobacteria,2K7N0@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_679630_14	1545915.JROG01000004_gene2501	8.559e-93	314.0	COG0745@1|root,COG0745@2|Bacteria,1RBJ1@1224|Proteobacteria,2U6DI@28211|Alphaproteobacteria,2K46Z@204457|Sphingomonadales	204457|Sphingomonadales	K	Two component transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_679630_5	1219049.SP5_060_00150	6.088e-171	544.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,2TR1H@28211|Alphaproteobacteria,2K0G3@204457|Sphingomonadales	204457|Sphingomonadales	E	Branched-chain amino acid aminotransferase	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
CMS1_k127_679630_24	1522072.IL54_3323	4.063e-63	230.0	COG1846@1|root,COG1846@2|Bacteria,1RIX7@1224|Proteobacteria,2U94M@28211|Alphaproteobacteria,2K4GP@204457|Sphingomonadales	204457|Sphingomonadales	K	MarR family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
CMS1_k127_679630_21	1248760.ANFZ01000006_gene2404	4.851e-67	237.0	COG5465@1|root,COG5465@2|Bacteria,1REC1@1224|Proteobacteria,2U7UP@28211|Alphaproteobacteria,2K1T3@204457|Sphingomonadales	204457|Sphingomonadales	S	Putative bacterial sensory transduction regulator	-	-	-	-	-	-	-	-	-	-	-	-	YbjN
CMS1_k127_679630_34	317655.Sala_0040	1.944e-30	125.0	COG2960@1|root,COG2960@2|Bacteria,1N725@1224|Proteobacteria,2UFEP@28211|Alphaproteobacteria,2K74V@204457|Sphingomonadales	204457|Sphingomonadales	S	Membrane fusogenic activity	-	-	-	ko:K09806	-	-	-	-	ko00000	-	-	-	BMFP
CMS1_k127_679630_23	1545915.JROG01000004_gene2393	5.773e-65	229.0	COG3476@1|root,COG3476@2|Bacteria,1MZC1@1224|Proteobacteria,2UBYB@28211|Alphaproteobacteria,2K4UV@204457|Sphingomonadales	204457|Sphingomonadales	T	Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)	bzrP	-	-	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	-	-	-	ko00000,ko00001,ko02000	9.A.24	-	-	TspO_MBR
CMS1_k127_679630_1	1545915.JROG01000003_gene1194	5.22e-266	830.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2TQMR@28211|Alphaproteobacteria,2K0VT@204457|Sphingomonadales	204457|Sphingomonadales	V	ABC-type multidrug transport system, ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS1_k127_679630_28	1545915.JROG01000003_gene1205	4.041e-53	190.0	COG0848@1|root,COG0848@2|Bacteria,1RHDF@1224|Proteobacteria,2UEA0@28211|Alphaproteobacteria,2K55Z@204457|Sphingomonadales	204457|Sphingomonadales	U	Biopolymer transport protein	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
CMS1_k127_679630_22	1248760.ANFZ01000009_gene1442	8.07e-67	231.0	COG0848@1|root,COG0848@2|Bacteria,1R64K@1224|Proteobacteria,2U4H6@28211|Alphaproteobacteria,2KD52@204457|Sphingomonadales	204457|Sphingomonadales	U	Biopolymer transport protein ExbD/TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
CMS1_k127_679630_13	1545915.JROG01000003_gene1207	1.694e-103	343.0	COG0811@1|root,COG0811@2|Bacteria,1NMPB@1224|Proteobacteria,2TS4F@28211|Alphaproteobacteria,2K1P2@204457|Sphingomonadales	204457|Sphingomonadales	U	MotA TolQ ExbB proton channel	exbB	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
CMS1_k127_679630_19	1123270.ATUR01000002_gene2076	2.493e-71	246.0	COG0810@1|root,COG0810@2|Bacteria,1RCAG@1224|Proteobacteria,2U664@28211|Alphaproteobacteria,2K187@204457|Sphingomonadales	204457|Sphingomonadales	M	Periplasmic protein TonB, links inner and outer membranes	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
CMS1_k127_679630_17	13690.CP98_01686	2.035e-79	274.0	2CJQX@1|root,342E0@2|Bacteria,1RA7X@1224|Proteobacteria,2U5C1@28211|Alphaproteobacteria,2KDDU@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_679630_4	1545915.JROG01000003_gene1495	3.738e-179	571.0	COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,2TQWS@28211|Alphaproteobacteria,2K2BW@204457|Sphingomonadales	204457|Sphingomonadales	E	homoserine dehydrogenase	thrA	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
CMS1_k127_679630_7	1522072.IL54_1876	2.954e-154	499.0	COG1494@1|root,COG1494@2|Bacteria,1MUB1@1224|Proteobacteria,2TSPE@28211|Alphaproteobacteria,2JZUH@204457|Sphingomonadales	204457|Sphingomonadales	G	in Escherichia coli this protein forms a dimer and binds manganese	glpX	-	3.1.3.11,3.1.3.37	ko:K11532	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R01845,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
CMS1_k127_679630_10	1502850.FG91_01180	2.039e-130	431.0	COG4782@1|root,COG4782@2|Bacteria,1MVAD@1224|Proteobacteria,2TTCR@28211|Alphaproteobacteria,2K84S@204457|Sphingomonadales	204457|Sphingomonadales	S	Alpha/beta hydrolase of unknown function (DUF900)	-	-	-	-	-	-	-	-	-	-	-	-	DUF900
CMS1_k127_679630_16	391625.PPSIR1_24229	3.234e-81	274.0	COG1573@1|root,COG1573@2|Bacteria,1R9XV@1224|Proteobacteria	1224|Proteobacteria	L	uracil-dna glycosylase	-	-	-	-	-	-	-	-	-	-	-	-	UDG
CMS1_k127_679630_20	1123504.JQKD01000060_gene2913	1.666e-68	235.0	COG0655@1|root,COG0655@2|Bacteria,1RAP5@1224|Proteobacteria,2VQVY@28216|Betaproteobacteria,4AK1I@80864|Comamonadaceae	28216|Betaproteobacteria	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
CMS1_k127_679630_0	1114964.L485_24645	2.651e-285	886.0	COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,2TRZQ@28211|Alphaproteobacteria,2K0VW@204457|Sphingomonadales	204457|Sphingomonadales	L	single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
CMS1_k127_679630_25	291985.CCSI01000005_gene949	4.244e-58	210.0	29TFP@1|root,30ENV@2|Bacteria,1RG86@1224|Proteobacteria,2UBEB@28211|Alphaproteobacteria,2K5KS@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
CMS1_k127_679630_18	1114964.L485_22935	6.005e-79	273.0	COG3332@1|root,COG3332@2|Bacteria,1RDBS@1224|Proteobacteria,2URNA@28211|Alphaproteobacteria,2KA3X@204457|Sphingomonadales	204457|Sphingomonadales	S	Transport and Golgi organisation 2	-	-	-	-	-	-	-	-	-	-	-	-	TANGO2
CMS1_k127_679630_27	1121949.AQXT01000002_gene2657	5.875e-55	198.0	COG2323@1|root,COG2323@2|Bacteria,1MW5I@1224|Proteobacteria,2U958@28211|Alphaproteobacteria,43YBK@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF421)	-	-	-	-	-	-	-	-	-	-	-	-	DUF421
CMS1_k127_679630_31	1120705.FG95_02300	2.004e-48	177.0	COG5592@1|root,COG5592@2|Bacteria,1RGUY@1224|Proteobacteria,2UD7B@28211|Alphaproteobacteria,2K3YV@204457|Sphingomonadales	204457|Sphingomonadales	S	Hemerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
CMS1_k127_679630_37	391595.RLO149_c001050	6.864e-07	51.0	2ENWN@1|root,33GHK@2|Bacteria,1NGHY@1224|Proteobacteria,2UMQR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_693695_1	392499.Swit_1860	4.567e-205	654.0	COG1053@1|root,COG1053@2|Bacteria,1MX84@1224|Proteobacteria,2U2Q1@28211|Alphaproteobacteria,2K1BC@204457|Sphingomonadales	204457|Sphingomonadales	C	PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein	-	-	1.3.99.5	ko:K16051	ko00984,ko01120,map00984,map01120	-	R01834	RC00145	ko00000,ko00001,ko01000	-	-	-	FAD_binding_2
CMS1_k127_693695_0	392499.Swit_1859	2.274e-309	965.0	COG1629@1|root,COG4771@2|Bacteria,1MWKN@1224|Proteobacteria,2UQ8T@28211|Alphaproteobacteria,2KDFW@204457|Sphingomonadales	204457|Sphingomonadales	P	Outer membrane protein beta-barrel family	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
CMS1_k127_694650_4	1123270.ATUR01000003_gene1171	3.166e-09	59.0	COG4067@1|root,COG4067@2|Bacteria,1RGX8@1224|Proteobacteria,2UC5Z@28211|Alphaproteobacteria,2K6SX@204457|Sphingomonadales	204457|Sphingomonadales	O	Ribosomal protein S6 modification protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn_protease
CMS1_k127_694650_0	1044.EH31_08510	1.327e-269	833.0	COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,2TSZY@28211|Alphaproteobacteria,2K25I@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.3,1.4.1.4	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
CMS1_k127_694650_2	1123270.ATUR01000003_gene1173	1.119e-47	178.0	COG3832@1|root,COG3832@2|Bacteria,1RH7Z@1224|Proteobacteria,2U9E1@28211|Alphaproteobacteria,2K54H@204457|Sphingomonadales	204457|Sphingomonadales	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1,Polyketide_cyc2
CMS1_k127_694650_1	1123269.NX02_20350	4.322e-105	346.0	COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,2TT6A@28211|Alphaproteobacteria,2JZW8@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
CMS1_k127_694650_3	1248760.ANFZ01000006_gene2726	2.409e-39	147.0	COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,2TQMT@28211|Alphaproteobacteria,2JZY0@204457|Sphingomonadales	204457|Sphingomonadales	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
CMS1_k127_69865_5	1030157.AFMP01000049_gene116	1.906e-25	110.0	COG0711@1|root,COG0711@2|Bacteria,1MZGU@1224|Proteobacteria,2UBVW@28211|Alphaproteobacteria,2K5D0@204457|Sphingomonadales	204457|Sphingomonadales	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF_1	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
CMS1_k127_69865_4	627192.SLG_22880	8.819e-40	153.0	COG0711@1|root,COG0711@2|Bacteria,1N0P5@1224|Proteobacteria,2U5DD@28211|Alphaproteobacteria,2K57Z@204457|Sphingomonadales	204457|Sphingomonadales	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF_2	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
CMS1_k127_69865_0	685778.AORL01000015_gene2365	1.58e-314	973.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,2TT32@28211|Alphaproteobacteria,2K1TK@204457|Sphingomonadales	204457|Sphingomonadales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_5,UVR,UvrC_HhH_N
CMS1_k127_69865_3	1030157.AFMP01000049_gene120	7.783e-81	278.0	COG1381@1|root,COG1381@2|Bacteria,1MVEJ@1224|Proteobacteria,2TTYW@28211|Alphaproteobacteria,2K120@204457|Sphingomonadales	204457|Sphingomonadales	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
CMS1_k127_69865_1	1248760.ANFZ01000006_gene2650	4.813e-166	531.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,2TQKG@28211|Alphaproteobacteria,2K1FE@204457|Sphingomonadales	204457|Sphingomonadales	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
CMS1_k127_69865_2	1550073.JROH01000047_gene3011	9.412e-116	375.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,2TTMF@28211|Alphaproteobacteria,2K056@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	metZ	-	2.5.1.48	ko:K01739,ko:K10764	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
CMS1_k127_71602_2	1123270.ATUR01000007_gene1377	1.317e-58	204.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,2TRE3@28211|Alphaproteobacteria,2K0GY@204457|Sphingomonadales	204457|Sphingomonadales	E	Aminotransferase	-	-	-	ko:K14261	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS1_k127_71602_0	1123270.ATUR01000003_gene1204	5.891e-218	688.0	COG3540@1|root,COG3540@2|Bacteria,1MWAF@1224|Proteobacteria,2U0FQ@28211|Alphaproteobacteria,2K06C@204457|Sphingomonadales	204457|Sphingomonadales	P	Alkaline phosphatase	-	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD,PhoD_N
CMS1_k127_71602_1	1248760.ANFZ01000009_gene1476	3.728e-76	266.0	COG1566@1|root,COG1566@2|Bacteria,1R50C@1224|Proteobacteria,2TUCN@28211|Alphaproteobacteria,2K0QD@204457|Sphingomonadales	204457|Sphingomonadales	V	Protein of unknown function (DUF3667)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3667
CMS1_k127_739622_0	1282876.BAOK01000001_gene2292	2.174e-270	835.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,2TSZZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG3653 N-acyl-D-aspartate D-glutamate deacylase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
CMS1_k127_739622_1	517722.AEUE01000001_gene2801	1.957e-132	430.0	COG4313@1|root,COG4313@2|Bacteria,1MXNW@1224|Proteobacteria,2TV0V@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl,Phenol_MetA_deg
CMS1_k127_746870_10	1123270.ATUR01000003_gene890	2.787e-40	154.0	COG0144@1|root,COG0144@2|Bacteria,1MV2Q@1224|Proteobacteria,2TS6U@28211|Alphaproteobacteria,2K17G@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	-	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F
CMS1_k127_746870_1	1248760.ANFZ01000013_gene1826	2.321e-260	809.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,2TQXC@28211|Alphaproteobacteria,2K0CG@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
CMS1_k127_746870_6	1537715.JQFJ01000002_gene1459	4.638e-106	361.0	COG2234@1|root,COG2234@2|Bacteria,1R88X@1224|Proteobacteria,2U1MC@28211|Alphaproteobacteria,2K3J3@204457|Sphingomonadales	204457|Sphingomonadales	S	M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
CMS1_k127_746870_4	1219049.SP5_001_00540	1.463e-150	481.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,2TRUY@28211|Alphaproteobacteria,2K2F3@204457|Sphingomonadales	204457|Sphingomonadales	O	COG0330 Membrane protease subunits, stomatin prohibitin homologs	qmcA	-	-	-	-	-	-	-	-	-	-	-	Band_7,Band_7_C
CMS1_k127_746870_11	1081640.AGFU01000061_gene208	5.507e-35	139.0	COG1585@1|root,COG1585@2|Bacteria,1N241@1224|Proteobacteria,2UC8X@28211|Alphaproteobacteria,2K5WQ@204457|Sphingomonadales	204457|Sphingomonadales	OU	Membrane protein implicated in regulation of membrane protease activity	-	-	-	ko:K07340	-	-	-	-	ko00000	-	-	-	NfeD
CMS1_k127_746870_9	1537715.JQFJ01000002_gene2286	2.635e-55	199.0	COG5403@1|root,COG5403@2|Bacteria,1N0H4@1224|Proteobacteria,2UFMN@28211|Alphaproteobacteria,2KC97@204457|Sphingomonadales	204457|Sphingomonadales	S	Bacterial protein of unknown function (DUF937)	-	-	-	-	-	-	-	-	-	-	-	-	DUF937
CMS1_k127_746870_8	1123270.ATUR01000010_gene1892	1.708e-87	293.0	COG1573@1|root,COG1573@2|Bacteria,1MW91@1224|Proteobacteria,2TSUP@28211|Alphaproteobacteria,2K0J4@204457|Sphingomonadales	204457|Sphingomonadales	L	Uracil-DNA glycosylase	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
CMS1_k127_746870_3	1248760.ANFZ01000009_gene1024	1.473e-153	488.0	COG0388@1|root,COG0388@2|Bacteria,1MXG5@1224|Proteobacteria,2TVCS@28211|Alphaproteobacteria,2K0V3@204457|Sphingomonadales	204457|Sphingomonadales	S	N-carbamoylputrescine amidase	aguB	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
CMS1_k127_746870_7	237727.NAP1_15138	2.568e-96	322.0	COG4798@1|root,COG4798@2|Bacteria,1NNHX@1224|Proteobacteria,2U5HN@28211|Alphaproteobacteria,2K2C2@204457|Sphingomonadales	204457|Sphingomonadales	S	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS1_k127_746870_5	1123270.ATUR01000010_gene1898	1.839e-119	392.0	COG2957@1|root,COG2957@2|Bacteria,1MX65@1224|Proteobacteria,2U0RR@28211|Alphaproteobacteria,2K0B9@204457|Sphingomonadales	204457|Sphingomonadales	E	Belongs to the agmatine deiminase family	-	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
CMS1_k127_746870_0	1123270.ATUR01000010_gene1899	1.021e-262	821.0	COG2234@1|root,COG2234@2|Bacteria,1MV86@1224|Proteobacteria,2TVJ5@28211|Alphaproteobacteria,2K04D@204457|Sphingomonadales	204457|Sphingomonadales	S	Peptidase, M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
CMS1_k127_746870_2	745310.G432_04120	2.209e-204	655.0	COG1506@1|root,COG1506@2|Bacteria,1MUJ3@1224|Proteobacteria,2U08D@28211|Alphaproteobacteria,2KD2V@204457|Sphingomonadales	204457|Sphingomonadales	E	Prolyl oligopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
CMS1_k127_748767_6	317655.Sala_2052	4.109e-06	53.0	COG1925@1|root,COG1925@2|Bacteria,1N6RM@1224|Proteobacteria,2UC0H@28211|Alphaproteobacteria,2K638@204457|Sphingomonadales	204457|Sphingomonadales	G	COG1925 Phosphotransferase system, HPr-related proteins	ptsH	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
CMS1_k127_748767_3	1219049.SP5_001_00580	6.681e-55	196.0	COG2893@1|root,COG2893@2|Bacteria,1RHH7@1224|Proteobacteria,2U9E5@28211|Alphaproteobacteria,2K4MZ@204457|Sphingomonadales	204457|Sphingomonadales	G	PTS fructose transporter subunit IIA	-	-	2.7.1.191	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1	-	-	EIIA-man
CMS1_k127_748767_2	1219045.BV98_000026	3.776e-114	379.0	COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,2TTI4@28211|Alphaproteobacteria,2K01M@204457|Sphingomonadales	204457|Sphingomonadales	T	Displays ATPase and GTPase activities	-	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
CMS1_k127_748767_5	627192.SLG_14770	5.773e-28	120.0	COG1493@1|root,COG1493@2|Bacteria,1NNN5@1224|Proteobacteria,2UFPB@28211|Alphaproteobacteria,2K65M@204457|Sphingomonadales	204457|Sphingomonadales	T	Serine kinase of the HPr protein, regulates carbohydrate metabolism	-	-	-	-	-	-	-	-	-	-	-	-	Hpr_kinase_C
CMS1_k127_748767_0	1545915.JROG01000001_gene528	3.801e-170	549.0	COG0642@1|root,COG2205@2|Bacteria,1N17V@1224|Proteobacteria,2TS69@28211|Alphaproteobacteria,2K1JA@204457|Sphingomonadales	204457|Sphingomonadales	T	Histidine kinase	-	-	2.7.13.3	ko:K14980	ko02020,map02020	M00520	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,Sensor_TM1,Stimulus_sens_1
CMS1_k127_748767_1	1090320.KB900605_gene2591	3.964e-117	381.0	COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,2TR43@28211|Alphaproteobacteria,2JZVH@204457|Sphingomonadales	204457|Sphingomonadales	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K14981	ko02020,map02020	M00520	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_748767_4	1219045.BV98_000030	1.227e-47	174.0	COG1866@1|root,COG1866@2|Bacteria,1MWXN@1224|Proteobacteria,2TRC4@28211|Alphaproteobacteria,2JZZG@204457|Sphingomonadales	204457|Sphingomonadales	H	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
CMS1_k127_807961_4	1144307.PMI04_02984	1.264e-89	299.0	COG2334@1|root,COG2334@2|Bacteria,1MUKJ@1224|Proteobacteria,2TS6D@28211|Alphaproteobacteria,2K09Q@204457|Sphingomonadales	204457|Sphingomonadales	F	Belongs to the pseudomonas-type ThrB family	thrB	-	2.7.1.39	ko:K02204	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	APH
CMS1_k127_807961_5	317655.Sala_1134	4.636e-69	236.0	COG0328@1|root,COG0328@2|Bacteria,1RCZ1@1224|Proteobacteria,2U7C4@28211|Alphaproteobacteria,2K3YC@204457|Sphingomonadales	204457|Sphingomonadales	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
CMS1_k127_807961_7	391600.ABRU01000059_gene2185	1.006e-18	93.0	COG3422@1|root,COG3422@2|Bacteria,1N6P8@1224|Proteobacteria,2UGRU@28211|Alphaproteobacteria,2KJ70@204458|Caulobacterales	204458|Caulobacterales	S	Domain of unknown function (DUF1508)	-	-	-	ko:K09946	-	-	-	-	ko00000	-	-	-	DUF1508
CMS1_k127_807961_1	1545915.JROG01000007_gene3110	1.169e-127	418.0	COG0665@1|root,COG0665@2|Bacteria,1MY0G@1224|Proteobacteria,2TRM2@28211|Alphaproteobacteria,2JZYS@204457|Sphingomonadales	204457|Sphingomonadales	E	Oxidoreductase	-	-	1.4.99.6	ko:K19746	ko00472,ko01100,map00472,map01100	-	R11018	RC00006	ko00000,ko00001,ko01000	-	-	-	DAO
CMS1_k127_807961_3	1545915.JROG01000007_gene3111	5.186e-102	342.0	COG2267@1|root,COG2267@2|Bacteria,1MWDA@1224|Proteobacteria,2TSZ4@28211|Alphaproteobacteria,2K0NG@204457|Sphingomonadales	204457|Sphingomonadales	I	Lysophospholipase	-	-	3.1.1.5	ko:K01048	ko00564,map00564	-	-	-	ko00000,ko00001,ko01000	-	-	-	Hydrolase_4
CMS1_k127_807961_6	983920.Y88_3610	4.372e-44	165.0	COG4960@1|root,COG4960@2|Bacteria,1RAYG@1224|Proteobacteria,2UJT9@28211|Alphaproteobacteria,2K6EK@204457|Sphingomonadales	204457|Sphingomonadales	OU	peptidase	cpaA	-	3.4.23.43	ko:K02278	-	-	-	-	ko00000,ko01000,ko02035,ko02044	-	-	-	Peptidase_A24
CMS1_k127_807961_2	1248760.ANFZ01000006_gene2381	6.045e-111	366.0	COG3745@1|root,COG3745@2|Bacteria,1MW75@1224|Proteobacteria,2TTPE@28211|Alphaproteobacteria,2K08W@204457|Sphingomonadales	204457|Sphingomonadales	U	Pilus assembly protein CpaB	cpaB	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	RcpC,SAF
CMS1_k127_807961_0	314225.ELI_01520	6.538e-144	466.0	COG4964@1|root,COG4964@2|Bacteria,1MV8G@1224|Proteobacteria,2TRNN@28211|Alphaproteobacteria,2K0ZQ@204457|Sphingomonadales	204457|Sphingomonadales	U	Belongs to the GSP D family	cpaC	-	-	ko:K02280	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	BON,Secretin,T2SS-T3SS_pil_N
CMS1_k127_856061_9	1479239.JQMU01000001_gene194	1.768e-24	103.0	COG2354@1|root,COG2354@2|Bacteria,1MVYU@1224|Proteobacteria,2TU43@28211|Alphaproteobacteria,2K0C1@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	ko:K09781	-	-	-	-	ko00000	-	-	-	DUF808
CMS1_k127_856061_0	1123270.ATUR01000003_gene681	5.45e-299	921.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,2TRI1@28211|Alphaproteobacteria,2K0V7@204457|Sphingomonadales	204457|Sphingomonadales	I	acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	pccB	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
CMS1_k127_856061_1	1248760.ANFZ01000009_gene1092	1.409e-217	682.0	COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,2TQS7@28211|Alphaproteobacteria,2K11W@204457|Sphingomonadales	204457|Sphingomonadales	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	-	-	1.8.1.7	ko:K00383	ko00480,ko04918,map00480,map04918	-	R00094,R00115	RC00011	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
CMS1_k127_856061_2	1219049.SP5_018_00600	7.109e-198	631.0	COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,2TQKP@28211|Alphaproteobacteria,2K0KU@204457|Sphingomonadales	204457|Sphingomonadales	G	Belongs to the GPI family	pgi	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
CMS1_k127_856061_4	1335760.ASTG01000025_gene1961	5.139e-116	379.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,2TR9N@28211|Alphaproteobacteria,2K1QM@204457|Sphingomonadales	204457|Sphingomonadales	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
CMS1_k127_856061_6	1219049.SP5_038_00190	4.642e-72	252.0	COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,2TTIA@28211|Alphaproteobacteria,2K1G1@204457|Sphingomonadales	204457|Sphingomonadales	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
CMS1_k127_856061_3	1112212.JH584235_gene1707	1.96e-132	428.0	COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,2TSHM@28211|Alphaproteobacteria,2K01W@204457|Sphingomonadales	204457|Sphingomonadales	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
CMS1_k127_856061_7	551789.ATVJ01000002_gene3073	6.103e-67	235.0	COG5553@1|root,COG5553@2|Bacteria,1PNX4@1224|Proteobacteria,2UZQZ@28211|Alphaproteobacteria,43ZRM@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Cysteine dioxygenase type I	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_856061_8	1449048.JQKU01000005_gene4674	1.607e-60	217.0	COG1733@1|root,COG1733@2|Bacteria,2GMK5@201174|Actinobacteria,236VX@1762|Mycobacteriaceae	201174|Actinobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR,SCP2
CMS1_k127_856061_5	1123269.NX02_29725	6.831e-112	366.0	COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,1MUFZ@1224|Proteobacteria,2TRGN@28211|Alphaproteobacteria,2K2HN@204457|Sphingomonadales	204457|Sphingomonadales	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
CMS1_k127_86038_12	493475.GARC_0766	2.196e-69	240.0	COG0178@1|root,COG0178@2|Bacteria,1MX79@1224|Proteobacteria,1RYSZ@1236|Gammaproteobacteria,465R7@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	ABC transporter	uvrA2	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
CMS1_k127_86038_2	1502850.FG91_03911	3.221e-174	555.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2TQN9@28211|Alphaproteobacteria,2K130@204457|Sphingomonadales	204457|Sphingomonadales	E	Threonine dehydratase	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PALP
CMS1_k127_86038_5	1120705.FG95_01350	7.221e-143	462.0	COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,2TT50@28211|Alphaproteobacteria,2K0B1@204457|Sphingomonadales	204457|Sphingomonadales	I	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
CMS1_k127_86038_1	1123270.ATUR01000004_gene1631	9.412e-239	749.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2TTRU@28211|Alphaproteobacteria,2K1UV@204457|Sphingomonadales	204457|Sphingomonadales	S	Metal-dependent hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
CMS1_k127_86038_6	1123270.ATUR01000004_gene1628	1.108e-128	414.0	COG2935@1|root,COG2935@2|Bacteria,1MW62@1224|Proteobacteria,2TQY8@28211|Alphaproteobacteria,2K00M@204457|Sphingomonadales	204457|Sphingomonadales	O	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate	ate	-	2.3.2.29	ko:K21420	-	-	R11547,R11548	RC00064	ko00000,ko01000	-	-	-	ATE_C,ATE_N
CMS1_k127_86038_15	1470591.BW41_01391	2.157e-36	155.0	COG3134@1|root,COG3134@2|Bacteria,1P46Z@1224|Proteobacteria,2UYWU@28211|Alphaproteobacteria,2KDGG@204457|Sphingomonadales	204457|Sphingomonadales	S	Nickel/cobalt transporter regulator	-	-	-	-	-	-	-	-	-	-	-	-	RcnB,Rick_17kDa_Anti
CMS1_k127_86038_13	1096930.L284_15230	6.412e-66	229.0	COG1956@1|root,COG1956@2|Bacteria,1RDBM@1224|Proteobacteria,2U595@28211|Alphaproteobacteria,2K4NG@204457|Sphingomonadales	204457|Sphingomonadales	T	GAF domain-containing protein	-	-	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF_2
CMS1_k127_86038_0	1207058.L53_11140	3.997e-286	894.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MWGR@1224|Proteobacteria,2TRTE@28211|Alphaproteobacteria,43X09@69657|Hyphomonadaceae	28211|Alphaproteobacteria	EU	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
CMS1_k127_86038_14	1112216.JH594425_gene2471	3.373e-43	164.0	COG0216@1|root,COG0216@2|Bacteria,1R348@1224|Proteobacteria,2TZXT@28211|Alphaproteobacteria,2KEW4@204457|Sphingomonadales	204457|Sphingomonadales	J	chain release factor	-	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
CMS1_k127_86038_4	1114964.L485_19330	4.011e-144	458.0	COG0745@1|root,COG0745@2|Bacteria,1MWVI@1224|Proteobacteria,2TRSP@28211|Alphaproteobacteria,2K0S8@204457|Sphingomonadales	204457|Sphingomonadales	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	ctrA	-	-	ko:K13584	ko02020,ko04112,map02020,map04112	M00512	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_86038_9	1545915.JROG01000004_gene1977	9.872e-102	337.0	COG0639@1|root,COG0639@2|Bacteria,1RD8M@1224|Proteobacteria,2U7N2@28211|Alphaproteobacteria,2K1WW@204457|Sphingomonadales	204457|Sphingomonadales	T	COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases	-	-	3.1.3.16	ko:K07313	-	-	-	-	ko00000,ko01000	-	-	-	Metallophos
CMS1_k127_86038_3	1502850.FG91_02127	3.156e-166	531.0	COG3268@1|root,COG3268@2|Bacteria,1MVI3@1224|Proteobacteria,2TV1G@28211|Alphaproteobacteria,2K2KQ@204457|Sphingomonadales	204457|Sphingomonadales	S	Saccharopine dehydrogenase NADP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Sacchrp_dh_NADP
CMS1_k127_86038_8	1219035.NT2_04_00410	1.099e-110	359.0	COG0717@1|root,COG0717@2|Bacteria,1MV2J@1224|Proteobacteria,2TSDM@28211|Alphaproteobacteria,2JZVF@204457|Sphingomonadales	204457|Sphingomonadales	F	Belongs to the dCTP deaminase family	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
CMS1_k127_86038_11	1346791.M529_21000	1.353e-78	274.0	COG3757@1|root,COG3757@2|Bacteria,1N792@1224|Proteobacteria,2TVI6@28211|Alphaproteobacteria,2K4F7@204457|Sphingomonadales	204457|Sphingomonadales	M	Glycosyl hydrolases family 25	-	-	-	ko:K07273	-	-	-	-	ko00000	-	-	-	Glyco_hydro_25
CMS1_k127_86038_10	1123270.ATUR01000008_gene256	8.886e-79	271.0	COG5328@1|root,COG5328@2|Bacteria,1RA93@1224|Proteobacteria,2U741@28211|Alphaproteobacteria,2K40E@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the UPF0262 family	-	-	-	-	-	-	-	-	-	-	-	-	UPF0262
CMS1_k127_86038_7	1207055.C100_14450	1.484e-124	404.0	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,2TSF9@28211|Alphaproteobacteria,2K1TQ@204457|Sphingomonadales	204457|Sphingomonadales	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
CMS1_k127_885012_2	566466.NOR53_2953	6.554e-29	121.0	COG2211@1|root,COG2211@2|Bacteria,1MVUM@1224|Proteobacteria,1RP5J@1236|Gammaproteobacteria,1J8AY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	MFS/sugar transport protein	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
CMS1_k127_885012_0	1123270.ATUR01000004_gene1668	0.0	1018.0	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,2TRCK@28211|Alphaproteobacteria,2JZUM@204457|Sphingomonadales	204457|Sphingomonadales	E	Peptidase family M3	dcp	-	3.4.15.5	ko:K01284	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
CMS1_k127_885012_1	1545915.JROG01000007_gene3146	3.051e-66	228.0	COG1409@1|root,COG1409@2|Bacteria,1MWKX@1224|Proteobacteria,2U5HA@28211|Alphaproteobacteria,2K0A3@204457|Sphingomonadales	204457|Sphingomonadales	S	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	cpdA	-	3.1.4.53	ko:K03651	ko00230,ko02025,map00230,map02025	-	R00191	RC00296	ko00000,ko00001,ko01000	-	-	-	Metallophos
CMS1_k127_895565_4	1123270.ATUR01000002_gene2237	5.759e-82	275.0	COG0225@1|root,COG0225@2|Bacteria,1MVUS@1224|Proteobacteria,2TSAM@28211|Alphaproteobacteria,2K0CZ@204457|Sphingomonadales	204457|Sphingomonadales	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
CMS1_k127_895565_0	1192759.AKIB01000103_gene3297	5.263e-148	472.0	COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,2TRT6@28211|Alphaproteobacteria,2K1NI@204457|Sphingomonadales	204457|Sphingomonadales	M	UTP-glucose-1-phosphate uridylyltransferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
CMS1_k127_895565_2	1248760.ANFZ01000009_gene1422	7.419e-87	298.0	COG0501@1|root,COG0501@2|Bacteria,1RH15@1224|Proteobacteria,2U9K7@28211|Alphaproteobacteria,2KCU5@204457|Sphingomonadales	204457|Sphingomonadales	O	Peptidase M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
CMS1_k127_895565_5	1123270.ATUR01000002_gene2239	2.447e-54	198.0	COG1280@1|root,COG1280@2|Bacteria,1MXAI@1224|Proteobacteria,2TSWP@28211|Alphaproteobacteria,2K2QW@204457|Sphingomonadales	204457|Sphingomonadales	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
CMS1_k127_895565_1	1248760.ANFZ01000018_gene601	1.467e-97	327.0	COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,2TRIG@28211|Alphaproteobacteria,2JZV3@204457|Sphingomonadales	204457|Sphingomonadales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS1_k127_895565_3	1248760.ANFZ01000018_gene600	1.901e-83	280.0	COG1741@1|root,COG1741@2|Bacteria,1MVSW@1224|Proteobacteria,2TSR6@28211|Alphaproteobacteria,2K0PN@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
CMS1_k127_903570_4	1449049.JONW01000005_gene823	1.589e-14	76.0	2DPV3@1|root,333H6@2|Bacteria,1NBKJ@1224|Proteobacteria,2UIZH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_903570_3	392499.Swit_3181	6.26e-30	126.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K02282,ko:K07782,ko:K19135	ko02020,ko02024,ko02026,map02020,map02024,map02026	-	-	-	ko00000,ko00001,ko02035,ko02044,ko02048,ko03000	-	-	-	Cas_NE0113,GerE,Response_reg,TPR_16
CMS1_k127_903570_0	247633.GP2143_02574	4.029e-178	576.0	COG2271@1|root,COG2271@2|Bacteria,1MWYR@1224|Proteobacteria,1RR7T@1236|Gammaproteobacteria	1224|Proteobacteria	G	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_903570_2	1174684.EBMC1_05439	8.401e-58	203.0	COG0824@1|root,COG0824@2|Bacteria,1NBU7@1224|Proteobacteria,2UF7N@28211|Alphaproteobacteria,2K6GH@204457|Sphingomonadales	204457|Sphingomonadales	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
CMS1_k127_903570_1	1545915.JROG01000001_gene465	8.878e-97	326.0	COG1024@1|root,COG1024@2|Bacteria,1PJ4R@1224|Proteobacteria,2TSSU@28211|Alphaproteobacteria,2K14X@204457|Sphingomonadales	204457|Sphingomonadales	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS1_k127_903570_5	1120705.FG95_03702	4.148e-09	57.0	COG3917@1|root,COG3917@2|Bacteria,1RDNQ@1224|Proteobacteria,2VGB4@28211|Alphaproteobacteria,2K3YE@204457|Sphingomonadales	204457|Sphingomonadales	Q	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
CMS1_k127_916387_3	1120705.FG95_02483	2.444e-38	152.0	COG0775@1|root,COG0775@2|Bacteria,1PVHN@1224|Proteobacteria,2V6WN@28211|Alphaproteobacteria,2KAR4@204457|Sphingomonadales	204457|Sphingomonadales	F	Phosphorylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PNP_UDP_1
CMS1_k127_916387_1	627192.SLG_21120	5.612e-76	259.0	COG0503@1|root,COG0503@2|Bacteria,1MVZ6@1224|Proteobacteria,2TV7J@28211|Alphaproteobacteria,2K25N@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
CMS1_k127_916387_0	1174684.EBMC1_03994	3.014e-171	546.0	COG2124@1|root,COG2124@2|Bacteria,1N0ID@1224|Proteobacteria,2TT7V@28211|Alphaproteobacteria,2K2ZK@204457|Sphingomonadales	204457|Sphingomonadales	C	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
CMS1_k127_916387_2	161528.ED21_20749	2.789e-55	196.0	COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,2U9FX@28211|Alphaproteobacteria,2K4H8@204457|Sphingomonadales	204457|Sphingomonadales	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
CMS1_k127_916387_4	1030157.AFMP01000065_gene1098	2.29e-20	91.0	COG0244@1|root,COG0244@2|Bacteria,1RAN5@1224|Proteobacteria,2U592@28211|Alphaproteobacteria,2K3XB@204457|Sphingomonadales	204457|Sphingomonadales	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
CMS1_k127_917688_7	1248760.ANFZ01000018_gene511	1.173e-51	184.0	COG2363@1|root,COG2363@2|Bacteria,1PX6Z@1224|Proteobacteria,2UDAX@28211|Alphaproteobacteria,2K69P@204457|Sphingomonadales	204457|Sphingomonadales	S	small membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF423
CMS1_k127_917688_0	291985.CCSI01000005_gene901	1.173e-179	575.0	COG0006@1|root,COG0006@2|Bacteria,1MVHD@1224|Proteobacteria,2UCJB@28211|Alphaproteobacteria,2K0RC@204457|Sphingomonadales	204457|Sphingomonadales	E	Metallopeptidase family M24	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M24
CMS1_k127_917688_2	1144305.PMI02_00861	1.359e-100	332.0	COG1335@1|root,COG1335@2|Bacteria,1NZJ1@1224|Proteobacteria,2VG5N@28211|Alphaproteobacteria,2KD04@204457|Sphingomonadales	204457|Sphingomonadales	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
CMS1_k127_917688_6	1415779.JOMH01000001_gene2774	2.297e-55	203.0	COG0500@1|root,COG2226@2|Bacteria,1QYM4@1224|Proteobacteria	1224|Proteobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_31
CMS1_k127_917688_3	1415779.JOMH01000001_gene978	9.33e-79	284.0	COG2907@1|root,COG2907@2|Bacteria,1MV4Z@1224|Proteobacteria,1S1C3@1236|Gammaproteobacteria,1X9GC@135614|Xanthomonadales	135614|Xanthomonadales	S	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_8
CMS1_k127_917688_4	1248760.ANFZ01000009_gene934	9.707e-79	271.0	COG1946@1|root,COG1946@2|Bacteria,1RDZN@1224|Proteobacteria,2U8ZQ@28211|Alphaproteobacteria,2K3PK@204457|Sphingomonadales	204457|Sphingomonadales	I	Thioesterase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_3
CMS1_k127_917688_8	1090318.ATTI01000001_gene3350	1.155e-41	156.0	COG0776@1|root,COG0776@2|Bacteria,1RH5Z@1224|Proteobacteria,2UCDG@28211|Alphaproteobacteria,2K62D@204457|Sphingomonadales	204457|Sphingomonadales	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	himA	-	-	ko:K04764	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
CMS1_k127_917688_9	1545915.JROG01000003_gene1461	4.034e-31	126.0	COG0789@1|root,COG0789@2|Bacteria,1RGYB@1224|Proteobacteria,2U9A5@28211|Alphaproteobacteria,2K5Y3@204457|Sphingomonadales	204457|Sphingomonadales	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
CMS1_k127_917688_10	1120705.FG95_01310	3.598e-29	121.0	2BJB4@1|root,3186Q@2|Bacteria,1NG3X@1224|Proteobacteria,2UG56@28211|Alphaproteobacteria,2K6X2@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_917688_5	1219045.BV98_001986	1.832e-68	237.0	COG2062@1|root,COG2062@2|Bacteria,1N0FX@1224|Proteobacteria,2UBYD@28211|Alphaproteobacteria,2K4JB@204457|Sphingomonadales	204457|Sphingomonadales	T	phosphohistidine phosphatase	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
CMS1_k127_917688_1	1331060.RLDS_22170	5.032e-147	470.0	COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,2TUKS@28211|Alphaproteobacteria,2K15X@204457|Sphingomonadales	204457|Sphingomonadales	KL	Helicase	dinG	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Helicase_C_2
CMS1_k127_923129_2	317655.Sala_0163	3.047e-29	116.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,2TSJY@28211|Alphaproteobacteria,2K0R8@204457|Sphingomonadales	204457|Sphingomonadales	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
CMS1_k127_923129_0	1545915.JROG01000003_gene1081	2.23e-179	580.0	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,2U35U@28211|Alphaproteobacteria,2K136@204457|Sphingomonadales	204457|Sphingomonadales	M	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	-	-	-	-	-	-	-	-	-	-	-	-	SLT
CMS1_k127_923129_1	1379701.JPJC01000006_gene401	3.545e-36	147.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,2UPFA@28211|Alphaproteobacteria,2KE1Y@204457|Sphingomonadales	204457|Sphingomonadales	L	uracil-DNA glycosylase	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
CMS1_k127_923129_3	1123270.ATUR01000003_gene708	4.252e-10	62.0	COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,1MVU6@1224|Proteobacteria,2TS0R@28211|Alphaproteobacteria,2K0PG@204457|Sphingomonadales	204457|Sphingomonadales	C	Electron transfer flavoprotein-ubiquinone oxidoreductase	-	-	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	ETF_QO,FAD_binding_2,NAD_binding_8
CMS1_k127_929442_7	1120705.FG95_00623	3.344e-38	150.0	COG0810@1|root,COG0810@2|Bacteria,1NB5F@1224|Proteobacteria,2UJ8K@28211|Alphaproteobacteria,2KDGQ@204457|Sphingomonadales	204457|Sphingomonadales	M	Gram-negative bacterial TonB protein C-terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
CMS1_k127_929442_8	582402.Hbal_0599	1.791e-32	132.0	COG3812@1|root,COG3812@2|Bacteria,1RGUV@1224|Proteobacteria,2U9BA@28211|Alphaproteobacteria,43Y6M@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DUF1993)	-	-	-	ko:K09983	-	-	-	-	ko00000	-	-	-	DUF1993
CMS1_k127_929442_9	237727.NAP1_14618	5.676e-23	112.0	2CIDE@1|root,348RV@2|Bacteria	2|Bacteria	S	MAPEG family	-	-	-	-	-	-	-	-	-	-	-	-	MAPEG
CMS1_k127_929442_6	1116369.KB890024_gene672	1.878e-38	155.0	COG2199@1|root,COG2199@2|Bacteria,1N66U@1224|Proteobacteria,2UCYF@28211|Alphaproteobacteria,43HFS@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
CMS1_k127_929442_0	1248760.ANFZ01000009_gene1227	0.0	1368.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2TRJF@28211|Alphaproteobacteria,2K1KW@204457|Sphingomonadales	204457|Sphingomonadales	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
CMS1_k127_929442_3	1522072.IL54_1969	7.278e-181	569.0	COG1294@1|root,COG1294@2|Bacteria,1MURP@1224|Proteobacteria,2TU3I@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	oxidase subunit	cydB	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
CMS1_k127_929442_2	1219035.NT2_26_00090	1.621e-256	796.0	COG1271@1|root,COG1271@2|Bacteria,1MV60@1224|Proteobacteria,2TQMA@28211|Alphaproteobacteria,2K0ZR@204457|Sphingomonadales	204457|Sphingomonadales	C	oxidase, subunit	cydA	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
CMS1_k127_929442_5	237727.NAP1_03180	3.035e-51	191.0	COG2259@1|root,COG2259@2|Bacteria,1P3TQ@1224|Proteobacteria,2UVGS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	DoxX	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
CMS1_k127_929442_1	1248760.ANFZ01000018_gene632	2.829e-286	888.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,2TT0G@28211|Alphaproteobacteria,2K3UQ@204457|Sphingomonadales	204457|Sphingomonadales	P	COG0659 Sulfate permease and related transporters (MFS superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	STAS,Sulfate_transp
CMS1_k127_929442_4	1545915.JROG01000004_gene2065	5.628e-63	216.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,2TW6Z@28211|Alphaproteobacteria,2K064@204457|Sphingomonadales	204457|Sphingomonadales	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	DUF442,Pyr_redox_2
CMS1_k127_936678_8	1550073.JROH01000025_gene1029	6.682e-27	109.0	COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,2TU1S@28211|Alphaproteobacteria,2K21H@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
CMS1_k127_936678_3	1120705.FG95_00638	1.268e-109	359.0	COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,2TU7F@28211|Alphaproteobacteria,2K0K0@204457|Sphingomonadales	204457|Sphingomonadales	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
CMS1_k127_936678_7	1174684.EBMC1_15402	4.732e-29	121.0	2AI43@1|root,3004D@2|Bacteria,1N2WG@1224|Proteobacteria,2UEQH@28211|Alphaproteobacteria,2KE63@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_936678_4	1090318.ATTI01000001_gene2820	1.966e-109	364.0	COG1281@1|root,COG1281@2|Bacteria,1MUMU@1224|Proteobacteria,2TTUR@28211|Alphaproteobacteria,2K0YD@204457|Sphingomonadales	204457|Sphingomonadales	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
CMS1_k127_936678_2	1545915.JROG01000009_gene2737	6.967e-159	505.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,2TR81@28211|Alphaproteobacteria,2K0CM@204457|Sphingomonadales	204457|Sphingomonadales	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
CMS1_k127_936678_1	1545915.JROG01000009_gene2736	3.636e-193	609.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,2TSGT@28211|Alphaproteobacteria,2K0I4@204457|Sphingomonadales	204457|Sphingomonadales	E	acetylornithine aminotransferase	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CMS1_k127_936678_0	517722.AEUE01000010_gene624	0.0	1304.0	COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,2TQJ7@28211|Alphaproteobacteria,2K0B7@204457|Sphingomonadales	204457|Sphingomonadales	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
CMS1_k127_936678_5	1248760.ANFZ01000004_gene1994	6.489e-54	191.0	COG3791@1|root,COG3791@2|Bacteria,1RHWZ@1224|Proteobacteria,2UBRG@28211|Alphaproteobacteria,2K5NY@204457|Sphingomonadales	204457|Sphingomonadales	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
CMS1_k127_936678_6	314225.ELI_11850	2.125e-33	140.0	2ERHA@1|root,33J2S@2|Bacteria,1NH9V@1224|Proteobacteria,2UJWK@28211|Alphaproteobacteria,2K7PE@204457|Sphingomonadales	204457|Sphingomonadales	S	GDYXXLXY protein	-	-	-	-	-	-	-	-	-	-	-	-	GDYXXLXY
CMS1_k127_936678_9	314225.ELI_11855	1.75e-20	94.0	COG4872@1|root,COG4872@2|Bacteria,1N4JN@1224|Proteobacteria,2UE2X@28211|Alphaproteobacteria,2K8KQ@204457|Sphingomonadales	204457|Sphingomonadales	S	Predicted membrane protein (DUF2157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2157
CMS1_k127_941367_6	291985.CCSI01000004_gene639	9.574e-52	184.0	COG0278@1|root,COG0278@2|Bacteria,1MZ4V@1224|Proteobacteria,2U9QB@28211|Alphaproteobacteria,2K55Y@204457|Sphingomonadales	204457|Sphingomonadales	O	Belongs to the glutaredoxin family. Monothiol subfamily	grxD	-	-	ko:K07390	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Glutaredoxin
CMS1_k127_941367_8	279238.Saro_2520	1.942e-28	115.0	COG0271@1|root,COG0271@2|Bacteria,1R3MM@1224|Proteobacteria,2UBUW@28211|Alphaproteobacteria,2K5YQ@204457|Sphingomonadales	204457|Sphingomonadales	T	Belongs to the BolA IbaG family	-	-	-	-	-	-	-	-	-	-	-	-	BolA
CMS1_k127_941367_7	1545915.JROG01000004_gene2282	2.5e-43	161.0	COG5467@1|root,COG5467@2|Bacteria,1MZRN@1224|Proteobacteria,2UC1G@28211|Alphaproteobacteria,2K533@204457|Sphingomonadales	204457|Sphingomonadales	S	Domain of unknown function (DUF1476)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1476
CMS1_k127_941367_1	745310.G432_17345	4.096e-160	510.0	COG0604@1|root,COG0604@2|Bacteria,1MWRK@1224|Proteobacteria,2TQMF@28211|Alphaproteobacteria,2K1HA@204457|Sphingomonadales	204457|Sphingomonadales	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_941367_2	1545915.JROG01000004_gene2280	8.657e-95	314.0	COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,2TRRS@28211|Alphaproteobacteria,2JZWQ@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
CMS1_k127_941367_0	1545915.JROG01000004_gene2277	1.188e-261	811.0	COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,2TR6K@28211|Alphaproteobacteria,2K0IM@204457|Sphingomonadales	204457|Sphingomonadales	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
CMS1_k127_941367_4	317655.Sala_2128	9.314e-84	306.0	COG3000@1|root,COG3000@2|Bacteria,1RJ68@1224|Proteobacteria,2U9CS@28211|Alphaproteobacteria,2K3D1@204457|Sphingomonadales	204457|Sphingomonadales	I	hydroxylase	-	-	1.14.15.24	ko:K15746	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00372	R07530,R07558,R07559,R07561,R07562,R07568,R07569,R07570,R07572,R07851,R09747	RC00478,RC00704,RC02629	ko00000,ko00001,ko00002,ko01000	-	-	-	FA_hydroxylase
CMS1_k127_941367_3	1502850.FG91_03273	3.639e-85	290.0	COG0189@1|root,COG0189@2|Bacteria,1MV29@1224|Proteobacteria,2U88X@28211|Alphaproteobacteria,2K3W3@204457|Sphingomonadales	204457|Sphingomonadales	HJ	COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase)	-	-	-	-	-	-	-	-	-	-	-	-	GSH-S_ATP
CMS1_k127_941367_9	1044.EH31_02640	2.126e-13	80.0	2B9GM@1|root,322UM@2|Bacteria,1P8TX@1224|Proteobacteria,2UWJQ@28211|Alphaproteobacteria,2KBSH@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_941367_5	1123270.ATUR01000003_gene1034	2.206e-67	235.0	COG0625@1|root,COG0625@2|Bacteria,1MXHH@1224|Proteobacteria,2TVGY@28211|Alphaproteobacteria,2K0MF@204457|Sphingomonadales	204457|Sphingomonadales	O	Glutathione S-transferase	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_C_3,GST_N
CMS1_k127_965999_2	1545915.JROG01000008_gene3457	1.802e-125	410.0	COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,2TQZW@28211|Alphaproteobacteria,2K0HT@204457|Sphingomonadales	204457|Sphingomonadales	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
CMS1_k127_965999_0	1248760.ANFZ01000011_gene182	1.671e-279	871.0	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,2TRJS@28211|Alphaproteobacteria,2K05A@204457|Sphingomonadales	204457|Sphingomonadales	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
CMS1_k127_965999_3	745310.G432_10160	3.65e-61	219.0	COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,2U9T9@28211|Alphaproteobacteria,2K4N2@204457|Sphingomonadales	204457|Sphingomonadales	J	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
CMS1_k127_965999_1	13689.BV96_01996	9.129e-126	407.0	COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,2TSWH@28211|Alphaproteobacteria,2K02Z@204457|Sphingomonadales	204457|Sphingomonadales	D	Chromosome partitioning	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
CMS1_k127_973165_3	59538.XP_005958566.1	2.049e-88	297.0	COG0807@1|root,KOG1284@2759|Eukaryota,39W81@33154|Opisthokonta,3BS70@33208|Metazoa	33154|Opisthokonta	H	riboflavin biosynthesis protein RIBA	-	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
CMS1_k127_973165_6	1219035.NT2_06_02790	1.334e-63	220.0	COG0054@1|root,COG0054@2|Bacteria,1RD9J@1224|Proteobacteria,2U9IZ@28211|Alphaproteobacteria,2K4FR@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
CMS1_k127_973165_9	702113.PP1Y_AT29542	8.359e-21	99.0	2A2SK@1|root,30R5Y@2|Bacteria,1NJX2@1224|Proteobacteria,2UJW5@28211|Alphaproteobacteria,2K6ID@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_973165_5	1304877.KI519399_gene5572	1.263e-74	255.0	COG0693@1|root,COG0693@2|Bacteria,1MY0C@1224|Proteobacteria,2U5BS@28211|Alphaproteobacteria,3JREZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	DJ-1/PfpI family	pfpI	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
CMS1_k127_973165_8	1248760.ANFZ01000002_gene3150	2.018e-41	158.0	COG0783@1|root,COG0783@2|Bacteria,1RAC5@1224|Proteobacteria,2U5Q5@28211|Alphaproteobacteria,2K3P2@204457|Sphingomonadales	204457|Sphingomonadales	P	Belongs to the Dps family	-	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
CMS1_k127_973165_4	1280950.HJO_14382	4.76e-81	279.0	COG4798@1|root,COG4798@2|Bacteria,1RHGZ@1224|Proteobacteria,2U69N@28211|Alphaproteobacteria,43XNX@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,PCMT
CMS1_k127_973165_0	1545915.JROG01000004_gene1748	1.113e-132	434.0	28MAA@1|root,2ZAP0@2|Bacteria,1R5EZ@1224|Proteobacteria,2U43A@28211|Alphaproteobacteria,2JZVU@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_973165_2	291985.CCSI01000004_gene740	4.38e-96	320.0	COG1226@1|root,2Z7ZD@2|Bacteria,1MXKM@1224|Proteobacteria,2TSNZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Ion transport protein	ccaA	-	-	ko:K08714	-	-	-	-	ko00000,ko02000	1.A.1.14	-	-	Ion_trans
CMS1_k127_973165_7	1125973.JNLC01000017_gene3629	6.246e-45	176.0	COG4544@1|root,COG4544@2|Bacteria,1MY56@1224|Proteobacteria,2TT91@28211|Alphaproteobacteria,3JRBP@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	SOS response	-	-	-	ko:K14160	-	-	-	-	ko00000,ko03400	-	-	-	-
CMS1_k127_973165_1	1174684.EBMC1_04719	2.171e-126	418.0	COG0389@1|root,COG0389@2|Bacteria,1MU5X@1224|Proteobacteria,2TQVR@28211|Alphaproteobacteria,2JZYV@204457|Sphingomonadales	204457|Sphingomonadales	L	Nucleotidyltransferase DNA polymerase involved in DNA repair	-	-	-	ko:K14161	-	-	-	-	ko00000,ko03400	-	-	-	IMS
CMS1_k127_982479_7	1449076.JOOE01000001_gene2198	4.078e-151	492.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,2TVFM@28211|Alphaproteobacteria,2K10T@204457|Sphingomonadales	204457|Sphingomonadales	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_2,RMMBL
CMS1_k127_982479_18	1207055.C100_19340	4.06e-58	211.0	COG0589@1|root,COG0589@2|Bacteria,1QD8E@1224|Proteobacteria,2TRQ7@28211|Alphaproteobacteria,2K4W9@204457|Sphingomonadales	204457|Sphingomonadales	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS1_k127_982479_15	745310.G432_11625	4.442e-88	307.0	COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,2TR7F@28211|Alphaproteobacteria,2K0YX@204457|Sphingomonadales	204457|Sphingomonadales	S	ABC-type (Unclassified) transport system, ATPase component	-	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
CMS1_k127_982479_23	1123229.AUBC01000007_gene211	4.065e-16	83.0	2ETWY@1|root,33ME5@2|Bacteria,1N72E@1224|Proteobacteria,2UIFQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_982479_2	279238.Saro_1579	1.284e-203	641.0	COG0427@1|root,COG0427@2|Bacteria,1MUGE@1224|Proteobacteria,2TZDG@28211|Alphaproteobacteria,2K2DE@204457|Sphingomonadales	204457|Sphingomonadales	C	Acetyl-CoA hydrolase/transferase C-terminal domain	-	-	-	ko:K18288	ko00660,map00660	-	R02407,R10600	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
CMS1_k127_982479_17	392499.Swit_1362	1.308e-59	213.0	COG1376@1|root,COG1376@2|Bacteria,1RKB2@1224|Proteobacteria,2UAA8@28211|Alphaproteobacteria,2K4DR@204457|Sphingomonadales	204457|Sphingomonadales	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD_2
CMS1_k127_982479_12	1331060.RLDS_00620	9.041e-102	344.0	COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,2TRJ9@28211|Alphaproteobacteria,2K0KA@204457|Sphingomonadales	204457|Sphingomonadales	S	protein conserved in bacteria	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	YkuD
CMS1_k127_982479_8	237727.NAP1_09267	1.346e-146	470.0	COG1239@1|root,COG1239@2|Bacteria,1MVD4@1224|Proteobacteria,2TRWU@28211|Alphaproteobacteria,2K1KE@204457|Sphingomonadales	204457|Sphingomonadales	H	Magnesium chelatase, subunit ChlI	-	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	Mg_chelatase
CMS1_k127_982479_9	383381.EH30_09670	9.684e-145	478.0	COG1240@1|root,COG1240@2|Bacteria,1MYHV@1224|Proteobacteria,2TTDY@28211|Alphaproteobacteria,2K1AY@204457|Sphingomonadales	204457|Sphingomonadales	H	von Willebrand factor type A domain	-	-	6.6.1.1	ko:K03404	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	VWA,VWA_2
CMS1_k127_982479_14	1248760.ANFZ01000002_gene3107	4.188e-98	329.0	COG2267@1|root,COG2267@2|Bacteria,1QUPE@1224|Proteobacteria,2TT7G@28211|Alphaproteobacteria,2K0DI@204457|Sphingomonadales	204457|Sphingomonadales	I	Alpha/beta hydrolase family	-	-	-	ko:K06049	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6
CMS1_k127_982479_13	1123267.JONN01000001_gene1487	1.055e-98	336.0	COG5621@1|root,COG5621@2|Bacteria,1QPJ4@1224|Proteobacteria,2TVNN@28211|Alphaproteobacteria,2K32K@204457|Sphingomonadales	204457|Sphingomonadales	S	hydroxyneurosporene synthase	-	-	4.2.1.131	ko:K09844	ko00906,ko01100,map00906,map01100	-	R07516,R07519,R07522,R07528,R07532,R07536,R07539,R07543,R09790	RC00966	ko00000,ko00001,ko01000	-	-	-	-
CMS1_k127_982479_4	685035.ADAE01000008_gene2906	8.15e-198	629.0	COG1233@1|root,COG1233@2|Bacteria,1MX1C@1224|Proteobacteria,2TS2R@28211|Alphaproteobacteria,2K0TG@204457|Sphingomonadales	204457|Sphingomonadales	Q	Flavin containing amine oxidoreductase	-	-	1.3.99.27	ko:K09845	ko00906,ko01100,map00906,map01100	-	R07517,R07520,R07523,R07534	RC02080	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
CMS1_k127_982479_11	1545915.JROG01000009_gene2747	9.237e-107	357.0	COG0500@1|root,COG0500@2|Bacteria,1QW86@1224|Proteobacteria,2TWSB@28211|Alphaproteobacteria,2KEKQ@204457|Sphingomonadales	204457|Sphingomonadales	Q	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
CMS1_k127_982479_10	1545915.JROG01000009_gene2748	6.146e-134	433.0	COG1063@1|root,COG1063@2|Bacteria,1MVZC@1224|Proteobacteria,2TRM6@28211|Alphaproteobacteria,2JZWZ@204457|Sphingomonadales	204457|Sphingomonadales	E	Dehydrogenase	-	-	1.1.1.396	ko:K11337	ko00860,ko01110,map00860,map01110	-	R09055	RC01377	ko00000,ko00001,ko01000	-	-	-	ADH_N
CMS1_k127_982479_3	1044.EH31_08750	2.236e-198	620.0	COG1348@1|root,COG1348@2|Bacteria,1MVTE@1224|Proteobacteria,2TSKC@28211|Alphaproteobacteria,2K0NE@204457|Sphingomonadales	204457|Sphingomonadales	D	Belongs to the NifH BchL ChlL family	-	-	1.3.7.14,1.3.7.15	ko:K11333	ko00860,ko01110,map00860,map01110	-	R09053,R09060	RC01008	ko00000,ko00001,ko01000	-	-	-	Fer4_NifH
CMS1_k127_982479_0	685035.ADAE01000008_gene2902	1.815e-272	844.0	COG2710@1|root,COG2710@2|Bacteria,1MUGI@1224|Proteobacteria,2TU7U@28211|Alphaproteobacteria,2K1QU@204457|Sphingomonadales	204457|Sphingomonadales	C	Nitrogenase component 1 type Oxidoreductase	-	-	1.3.7.14,1.3.7.15	ko:K11334	ko00860,ko01110,map00860,map01110	-	R09053,R09060	RC01008	ko00000,ko00001,ko01000	-	-	-	Oxidored_nitro
CMS1_k127_982479_1	1248917.ANFX01000016_gene2456	1.583e-262	822.0	COG2710@1|root,COG2710@2|Bacteria,1MW4U@1224|Proteobacteria,2TT9B@28211|Alphaproteobacteria,2K2I9@204457|Sphingomonadales	204457|Sphingomonadales	C	Proto-chlorophyllide reductase 57 kD subunit	bchZ	-	1.3.7.14,1.3.7.15	ko:K11335	ko00860,ko01110,map00860,map01110	-	R09053,R09060	RC01008	ko00000,ko00001,ko01000	-	-	-	Oxidored_nitro,PCP_red
CMS1_k127_982479_20	1550073.JROH01000005_gene1629	5.019e-30	120.0	2DPVW@1|root,333MC@2|Bacteria,1N7PY@1224|Proteobacteria,2VEKS@28211|Alphaproteobacteria,2K833@204457|Sphingomonadales	204457|Sphingomonadales	C	Antenna complex alpha/beta subunit	-	-	-	ko:K08927	ko02020,map02020	-	-	-	ko00000,ko00001,ko00194	-	-	-	LHC
CMS1_k127_982479_21	1267005.KB911258_gene58	1.561e-21	95.0	2EI15@1|root,33BSN@2|Bacteria,1N7FB@1224|Proteobacteria,2UFDP@28211|Alphaproteobacteria,3N97K@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	C	Antenna complex alpha/beta subunit	pufA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K08926	ko02020,map02020	-	-	-	ko00000,ko00001,ko00194	-	-	-	LHC
CMS1_k127_982479_6	1112212.JH584235_gene2043	2.216e-160	507.0	2DB77@1|root,2Z7K3@2|Bacteria,1NHMC@1224|Proteobacteria,2U06K@28211|Alphaproteobacteria,2K1RB@204457|Sphingomonadales	204457|Sphingomonadales	S	Belongs to the reaction center PufL M PsbA D family	-	-	-	ko:K08928	ko02020,map02020	M00597	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	Photo_RC
CMS1_k127_982479_5	685035.ADAE01000008_gene2897	1.181e-170	538.0	2DBBD@1|root,2Z87P@2|Bacteria,1MWZI@1224|Proteobacteria,2TT76@28211|Alphaproteobacteria,2K2SW@204457|Sphingomonadales	204457|Sphingomonadales	C	The reaction center is a membrane-bound complex that mediates the initial photochemical event in the electron transfer process of photosynthesis	-	-	-	ko:K08929	ko02020,map02020	M00597	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	Photo_RC
CMS1_k127_982479_22	383381.EH30_09740	1.283e-17	92.0	297GI@1|root,2ZUPU@2|Bacteria,1N9UR@1224|Proteobacteria,2UIW7@28211|Alphaproteobacteria,2K6V3@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_982479_19	685035.ADAE01000008_gene2895	6.863e-55	197.0	COG3476@1|root,COG3476@2|Bacteria,1MZC1@1224|Proteobacteria,2U8I1@28211|Alphaproteobacteria,2K4VZ@204457|Sphingomonadales	204457|Sphingomonadales	T	TspO/MBR family	-	-	-	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	-	-	-	ko00000,ko00001,ko02000	9.A.24	-	-	TspO_MBR
CMS1_k127_982479_16	1545915.JROG01000009_gene2677	9.215e-86	286.0	COG0644@1|root,COG0644@2|Bacteria,1MXQY@1224|Proteobacteria,2TVK0@28211|Alphaproteobacteria,2K22X@204457|Sphingomonadales	204457|Sphingomonadales	C	geranylgeranyl reductase	-	-	1.3.1.111,1.3.1.83	ko:K10960	ko00860,ko00900,ko01100,ko01110,map00860,map00900,map01100,map01110	-	R02063,R08754,R08755,R08756,R11226,R11518	RC00212,RC00522,RC01823	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3,Lycopene_cycl,NAD_binding_8,Pyr_redox_2
CMS1_k127_989053_7	1207055.C100_01425	1.175e-121	400.0	COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,2TRQA@28211|Alphaproteobacteria,2K178@204457|Sphingomonadales	204457|Sphingomonadales	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
CMS1_k127_989053_8	1545915.JROG01000007_gene3139	3.511e-36	145.0	2AK00@1|root,32PGE@2|Bacteria,1NEPB@1224|Proteobacteria,2UFQJ@28211|Alphaproteobacteria,2K6PN@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_989053_0	1123270.ATUR01000002_gene2461	6.831e-229	721.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,2TSHQ@28211|Alphaproteobacteria,2K0Y2@204457|Sphingomonadales	204457|Sphingomonadales	M	Cell division protein FtsI penicillin-binding protein	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
CMS1_k127_989053_1	1248760.ANFZ01000006_gene2357	1.987e-222	698.0	COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,2TVXI@28211|Alphaproteobacteria,2K12F@204457|Sphingomonadales	204457|Sphingomonadales	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS1_k127_989053_5	1248760.ANFZ01000006_gene2358	6.511e-170	545.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,2TR0Q@28211|Alphaproteobacteria,2K1N2@204457|Sphingomonadales	204457|Sphingomonadales	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS1_k127_989053_3	1123270.ATUR01000002_gene2464	8.908e-177	559.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,2TRUG@28211|Alphaproteobacteria,2K18Y@204457|Sphingomonadales	204457|Sphingomonadales	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
CMS1_k127_989053_2	279238.Saro_1131	3.63e-178	571.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,2TTE8@28211|Alphaproteobacteria,2K1GM@204457|Sphingomonadales	204457|Sphingomonadales	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
CMS1_k127_989053_6	1248760.ANFZ01000006_gene2361	2.128e-165	531.0	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,2TQSA@28211|Alphaproteobacteria,2K0IS@204457|Sphingomonadales	204457|Sphingomonadales	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
CMS1_k127_989053_4	1123270.ATUR01000002_gene2467	2.624e-171	543.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,2TSEY@28211|Alphaproteobacteria,2K0YF@204457|Sphingomonadales	204457|Sphingomonadales	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
CMS1_k127_992119_7	1346791.M529_01120	2.96e-31	125.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,2U103@28211|Alphaproteobacteria,2K0W4@204457|Sphingomonadales	204457|Sphingomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
CMS1_k127_992119_3	46429.BV95_04207	5.476e-100	331.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,2U0M2@28211|Alphaproteobacteria,2K2B0@204457|Sphingomonadales	204457|Sphingomonadales	KT	Response regulator of the LytR AlgR family	-	-	-	ko:K08083	ko02020,map02020	M00493	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	LytTR,Response_reg
CMS1_k127_992119_1	1282876.BAOK01000001_gene3513	4.046e-198	628.0	COG0671@1|root,COG0671@2|Bacteria,1MWK1@1224|Proteobacteria,2U0HJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
CMS1_k127_992119_0	1121949.AQXT01000002_gene1365	0.0	1061.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TRFN@28211|Alphaproteobacteria,43Z2T@69657|Hyphomonadaceae	28211|Alphaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.17.1.4	ko:K11177	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
CMS1_k127_992119_2	1123270.ATUR01000007_gene1267	1.065e-149	483.0	COG1319@1|root,COG1319@2|Bacteria,1MVJS@1224|Proteobacteria,2TRAR@28211|Alphaproteobacteria,2K1FP@204457|Sphingomonadales	204457|Sphingomonadales	C	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM	-	-	1.17.1.4	ko:K11178	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
CMS1_k127_992119_4	1123270.ATUR01000007_gene1266	7.408e-91	303.0	COG2080@1|root,COG2080@2|Bacteria,1MY3F@1224|Proteobacteria,2TRGH@28211|Alphaproteobacteria,2K11H@204457|Sphingomonadales	204457|Sphingomonadales	C	aerobic-type carbon monoxide dehydrogenase, small subunit CoxS	-	-	-	ko:K13483	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002	-	-	-	Fer2,Fer2_2
CMS1_k127_992119_8	1030157.AFMP01000036_gene2558	6.149e-19	91.0	2EHCE@1|root,33B49@2|Bacteria,1NIBN@1224|Proteobacteria,2VCY9@28211|Alphaproteobacteria,2K7EY@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_992119_6	1042326.AZNV01000024_gene2391	3.189e-34	133.0	COG1309@1|root,COG1309@2|Bacteria,1RC7C@1224|Proteobacteria,2U5YR@28211|Alphaproteobacteria,4B8MP@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
## 2572 queries scanned
## Total time (seconds): 39.15864014625549
## Rate: 65.68 q/s