## Tue Oct 15 12:36:06 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/Potential_rubisco_autotrophic/CMS1_bin.118.fa -m mmseqs --itype genome -o CMS1_bin.118 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/all_bins_1385/CMS1_bin.118 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
CMS1_k127_1007443_2	7668.SPU_018754-tr	3.836e-30	128.0	COG0666@1|root,KOG4177@2759|Eukaryota,38BVK@33154|Opisthokonta,3BGGV@33208|Metazoa,3CT1S@33213|Bilateria	33208|Metazoa	M	ankyrin 3, node of Ranvier (ankyrin G)	-	-	-	-	-	-	-	-	-	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5,ZU5
CMS1_k127_1007443_1	1499967.BAYZ01000061_gene5938	1.239e-42	179.0	COG2755@1|root,COG5617@1|root,COG2755@2|Bacteria,COG5617@2|Bacteria,2NS5H@2323|unclassified Bacteria	2|Bacteria	E	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2,YfhO,cNMP_binding
CMS1_k127_1007443_0	251229.Chro_3610	2.245e-85	289.0	COG1452@1|root,COG1452@2|Bacteria,1G0TW@1117|Cyanobacteria,3VHNX@52604|Pleurocapsales	1117|Cyanobacteria	M	PFAM Mannosyl oligosaccharide glucosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_63
CMS1_k127_1009753_3	479433.Caci_4099	1.027e-17	98.0	COG1472@1|root,COG1472@2|Bacteria,2GJ5H@201174|Actinobacteria	201174|Actinobacteria	G	hydrolase, family 3	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	CBM_6,F5_F8_type_C,Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,Ricin_B_lectin
CMS1_k127_1009753_1	1169152.AXVD01000014_gene1368	3.925e-113	381.0	COG4257@1|root,COG4257@2|Bacteria,2GUYF@201174|Actinobacteria,4FXUH@85025|Nocardiaceae	201174|Actinobacteria	V	antibiotic catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1009753_0	290397.Adeh_3913	4.189e-119	399.0	COG3547@1|root,COG3547@2|Bacteria,1NN5F@1224|Proteobacteria,42X06@68525|delta/epsilon subdivisions,2WWJ3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Transposase (IS116 IS110 IS902 family)	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1009753_2	467200.ACFA01000399_gene2578	5.729e-51	196.0	COG3547@1|root,COG3547@2|Bacteria,2I4I8@201174|Actinobacteria	201174|Actinobacteria	L	Transposase (IS116 IS110 IS902 family)	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1024982_2	1123318.KB904629_gene2080	7.889e-07	50.0	COG3655@1|root,COG3655@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	ko:K07727	-	-	-	-	ko00000,ko03000	-	-	-	HTH_26,HTH_3
CMS1_k127_1024982_0	243231.GSU0193	1.234e-158	510.0	COG2133@1|root,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,42MU3@68525|delta/epsilon subdivisions,2WKTF@28221|Deltaproteobacteria,43SSU@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
CMS1_k127_1024982_1	338966.Ppro_2754	1.784e-48	186.0	COG0535@1|root,COG0535@2|Bacteria,1RG5U@1224|Proteobacteria,42RKR@68525|delta/epsilon subdivisions,2WNUX@28221|Deltaproteobacteria,43VVF@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
CMS1_k127_102606_2	1210884.HG799465_gene12178	5.536e-29	123.0	COG1595@1|root,COG1595@2|Bacteria,2J0XE@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_102606_3	1499967.BAYZ01000153_gene1547	1.765e-25	109.0	COG1487@1|root,COG1487@2|Bacteria,2NS1P@2323|unclassified Bacteria	2|Bacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
CMS1_k127_102606_7	1229172.JQFA01000002_gene4496	5.743e-12	69.0	2DTYB@1|root,33N7I@2|Bacteria,1GRBI@1117|Cyanobacteria,1HIBA@1150|Oscillatoriales	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2281
CMS1_k127_102606_10	1121447.JONL01000022_gene3720	1.674e-06	49.0	2EPJ6@1|root,33H5U@2|Bacteria	2|Bacteria	S	Unextendable partial coding region	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_102606_0	985867.AEWF01000006_gene496	5.582e-48	173.0	2AU0F@1|root,31JKB@2|Bacteria,1RGGF@1224|Proteobacteria,2U8PC@28211|Alphaproteobacteria,47G6G@766|Rickettsiales	766|Rickettsiales	S	COG NOG14600 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_102606_8	1329250.WOSG25_280020	1.017e-11	64.0	2DPII@1|root,3327T@2|Bacteria,1VHT9@1239|Firmicutes,4HQ1F@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_102606_1	498761.HM1_3128	1.178e-30	123.0	2B9ZZ@1|root,323DM@2|Bacteria,1V6N4@1239|Firmicutes,24K1H@186801|Clostridia	186801|Clostridia	S	COG NOG15344 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_102606_6	632245.CLP_4083	6.155e-14	73.0	2ED6K@1|root,3373A@2|Bacteria,1VI2S@1239|Firmicutes,24QZV@186801|Clostridia,36TJ8@31979|Clostridiaceae	186801|Clostridia	S	the current gene model (or a revised gene model) may contain one or more premature stops and or frameshifts	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_102606_15	926551.KB900730_gene1710	0.0001499	45.0	2EJFV@1|root,33D6V@2|Bacteria,4NYMX@976|Bacteroidetes,1I6TP@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_102606_9	1408823.AXUS01000040_gene1668	4.846e-10	59.0	2C8B1@1|root,2ZGXF@2|Bacteria,1W39A@1239|Firmicutes,24W8J@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_102606_16	221288.JH992901_gene4351	0.0002224	46.0	2BXJK@1|root,33AIX@2|Bacteria,1GFAX@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_102606_5	525264.HMPREF0305_11005	7.296e-19	87.0	2BXJK@1|root,33AIX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_102606_4	986075.CathTA2_0037	2.204e-24	111.0	2AHMV@1|root,317ZT@2|Bacteria,1VPFH@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1036974_3	1192034.CAP_6791	1.45e-12	78.0	2C4KT@1|root,340PA@2|Bacteria,1NYVI@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1036974_0	1218075.BAYA01000020_gene4999	8.805e-62	225.0	COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,2VMYS@28216|Betaproteobacteria,1K5HY@119060|Burkholderiaceae	28216|Betaproteobacteria	P	abc transporter	cmpD_2	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
CMS1_k127_1036974_2	1034769.KB910518_gene2215	1.569e-24	116.0	COG0600@1|root,COG0600@2|Bacteria,1UYCY@1239|Firmicutes,4HFWQ@91061|Bacilli,276HI@186822|Paenibacillaceae	91061|Bacilli	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
CMS1_k127_1036974_1	1122179.KB890477_gene3200	3.87e-40	169.0	COG0715@1|root,COG2885@1|root,COG0715@2|Bacteria,COG2885@2|Bacteria,4NM1E@976|Bacteroidetes,1IWA5@117747|Sphingobacteriia	976|Bacteroidetes	MP	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2,OmpA
CMS1_k127_1036974_4	378806.STAUR_6365	0.0003947	51.0	COG1842@1|root,COG1842@2|Bacteria,1NNUD@1224|Proteobacteria,438WP@68525|delta/epsilon subdivisions,2X9RW@28221|Deltaproteobacteria,2YY15@29|Myxococcales	28221|Deltaproteobacteria	KT	PspA/IM30 family	-	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
CMS1_k127_1048187_0	1123274.KB899409_gene630	9.629e-186	587.0	COG1900@1|root,COG1900@2|Bacteria,2J6WE@203691|Spirochaetes	203691|Spirochaetes	S	Homocysteine biosynthesis enzyme, sulfur-incorporation	-	-	-	-	-	-	-	-	-	-	-	-	HcyBio
CMS1_k127_1048187_1	446465.Bfae_24480	0.0009906	45.0	COG2608@1|root,COG2608@2|Bacteria,2GQMZ@201174|Actinobacteria,4FDXU@85020|Dermabacteraceae	201174|Actinobacteria	P	Heavy-metal-associated domain	copZ	-	-	-	-	-	-	-	-	-	-	-	HMA
CMS1_k127_1049703_2	1267535.KB906767_gene1337	2.462e-10	61.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	ytaP	-	-	-	-	-	-	-	-	-	-	-	AXE1,Abhydrolase_7,DLH,Peptidase_S15,Peptidase_S9
CMS1_k127_1049703_1	1123277.KB893211_gene4412	4.362e-127	417.0	COG4409@1|root,COG4409@2|Bacteria,4NIJX@976|Bacteroidetes,47MH2@768503|Cytophagia	976|Bacteroidetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
CMS1_k127_1049703_0	880073.Calab_3403	7.935e-150	481.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,2NNV3@2323|unclassified Bacteria	2|Bacteria	C	Malic enzyme, NAD binding domain	maeB	GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0055114	1.1.1.38,1.1.1.40,2.3.1.8	ko:K00027,ko:K00029,ko:K00625,ko:K04020,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,ko02020,map00430,map00620,map00640,map00680,map00710,map00720,map01100,map01120,map01200,map02020	M00169,M00172,M00357,M00579	R00214,R00216,R00230,R00921	RC00004,RC00105,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1637	Malic_M,PTA_PTB,malic
CMS1_k127_1050292_9	1210884.HG799466_gene12650	4.21e-49	198.0	28IKQ@1|root,2Z8MC@2|Bacteria,2IXYY@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane
CMS1_k127_1050292_4	1210884.HG799466_gene12649	1.182e-87	296.0	COG1131@1|root,COG1131@2|Bacteria,2IY1H@203682|Planctomycetes	203682|Planctomycetes	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_1050292_13	1129374.AJE_05736	1.788e-24	117.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,1RN8S@1236|Gammaproteobacteria,465IC@72275|Alteromonadaceae	1236|Gammaproteobacteria	NU	COG4972 Tfp pilus assembly protein, ATPase PilM	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
CMS1_k127_1050292_20	1123296.JQKE01000069_gene1879	8.418e-10	67.0	COG3167@1|root,COG3167@2|Bacteria,1RBGW@1224|Proteobacteria,2VH68@28216|Betaproteobacteria,2KR65@206351|Neisseriales	206351|Neisseriales	NU	Pilus assembly protein, PilO	pilO	-	-	ko:K02664	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilO
CMS1_k127_1050292_11	317013.NY99_03070	1.047e-37	165.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,1RN3Z@1236|Gammaproteobacteria,1X3SF@135614|Xanthomonadales	135614|Xanthomonadales	U	Type II secretory pathway, component HofQ	pilQ	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
CMS1_k127_1050292_21	583355.Caka_2450	1.55e-07	57.0	28X6Y@1|root,2ZJ59@2|Bacteria,46WIZ@74201|Verrucomicrobia,3K8DC@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1050292_17	997346.HMPREF9374_1243	3.876e-15	89.0	COG3387@1|root,COG3387@2|Bacteria,1TR12@1239|Firmicutes,4HD33@91061|Bacilli,27CHM@186824|Thermoactinomycetaceae	91061|Bacilli	G	Glycosyl hydrolases family 15	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
CMS1_k127_1050292_7	439235.Dalk_0967	2.348e-65	231.0	COG1714@1|root,COG1714@2|Bacteria,1RJRV@1224|Proteobacteria	1224|Proteobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
CMS1_k127_1050292_12	439235.Dalk_0968	2.277e-34	139.0	2ECUE@1|root,336RY@2|Bacteria,1P3V9@1224|Proteobacteria,431ZA@68525|delta/epsilon subdivisions,2WX45@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1050292_19	497964.CfE428DRAFT_2654	2.272e-10	73.0	2EG13@1|root,339T4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1050292_14	497964.CfE428DRAFT_2655	2.298e-20	94.0	2ES4R@1|root,33JPJ@2|Bacteria,46T9B@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1050292_3	497964.CfE428DRAFT_2656	3.559e-93	328.0	2EQIM@1|root,2ZBQ8@2|Bacteria,46TFZ@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF4129)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
CMS1_k127_1050292_8	497964.CfE428DRAFT_2657	4.783e-59	223.0	COG5414@1|root,COG5414@2|Bacteria,46VD3@74201|Verrucomicrobia	74201|Verrucomicrobia	K	histone acetyltransferase binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1050292_1	497964.CfE428DRAFT_2658	3.744e-150	481.0	COG0714@1|root,COG0714@2|Bacteria,46S8X@74201|Verrucomicrobia	74201|Verrucomicrobia	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS1_k127_1050292_0	497964.CfE428DRAFT_2659	3.492e-154	499.0	COG1721@1|root,COG1721@2|Bacteria,46SN6@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CMS1_k127_1050292_2	398767.Glov_3575	2.428e-110	366.0	COG1300@1|root,COG1300@2|Bacteria,1Q1GN@1224|Proteobacteria,42UUJ@68525|delta/epsilon subdivisions,2WQQ0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Stage II sporulation protein M	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIM
CMS1_k127_1050292_5	497964.CfE428DRAFT_2661	6.911e-83	284.0	COG1714@1|root,COG1714@2|Bacteria,46UT5@74201|Verrucomicrobia	74201|Verrucomicrobia	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
CMS1_k127_1050292_18	179408.Osc7112_3312	1.539e-11	74.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1G2CX@1117|Cyanobacteria,1HA2Y@1150|Oscillatoriales	1117|Cyanobacteria	O	Glycosyl transferase family 41	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,TPR_1,TPR_11,TPR_2,TPR_8
CMS1_k127_1050292_6	321332.CYB_0455	1.492e-76	268.0	COG0854@1|root,COG0854@2|Bacteria,1G0QW@1117|Cyanobacteria,1GZKF@1129|Synechococcus	1117|Cyanobacteria	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
CMS1_k127_1050292_15	1220534.B655_1281	7.532e-19	91.0	COG1366@1|root,arCOG06891@2157|Archaea,2Y4H8@28890|Euryarchaeota	28890|Euryarchaeota	T	STAS domain	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
CMS1_k127_1050292_10	1220534.B655_1045	8.923e-45	184.0	COG0457@1|root,COG0515@1|root,arCOG03038@2157|Archaea,arCOG03682@2157|Archaea,2XYM9@28890|Euryarchaeota,23PP8@183925|Methanobacteria	183925|Methanobacteria	T	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_8
CMS1_k127_1050292_16	329726.AM1_2213	2.462e-17	96.0	COG5305@1|root,COG5305@2|Bacteria,1G5JV@1117|Cyanobacteria	1117|Cyanobacteria	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS1_k127_1050446_21	926569.ANT_08110	1.079e-40	152.0	COG1940@1|root,COG1940@2|Bacteria	2|Bacteria	GK	ROK family	-	-	2.7.1.188,2.7.1.2,2.7.1.214,2.7.1.60,5.1.3.9	ko:K00845,ko:K13967,ko:K19979,ko:K20433	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko00525,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map00525,map01100,map01110,map01120,map01130,map01200	M00001,M00549,M00814,M00815	R00299,R01600,R01786,R02087,R02705,R11185,R11234	RC00002,RC00017,RC00290	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
CMS1_k127_1050446_8	926569.ANT_08100	1.223e-107	357.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	-	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
CMS1_k127_1050446_16	439235.Dalk_0759	1.014e-63	229.0	COG0614@1|root,COG0614@2|Bacteria,1MWVF@1224|Proteobacteria,42PQA@68525|delta/epsilon subdivisions,2WKNZ@28221|Deltaproteobacteria,2MIYZ@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
CMS1_k127_1050446_17	439235.Dalk_0760	6.469e-63	227.0	COG1120@1|root,COG1120@2|Bacteria,1MUNG@1224|Proteobacteria,42P8N@68525|delta/epsilon subdivisions,2WIWA@28221|Deltaproteobacteria,2MIT5@213118|Desulfobacterales	28221|Deltaproteobacteria	HP	PFAM ABC transporter related	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
CMS1_k127_1050446_15	439235.Dalk_0761	3.499e-68	245.0	COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,42PIH@68525|delta/epsilon subdivisions,2WJH2@28221|Deltaproteobacteria,2MIKZ@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
CMS1_k127_1050446_7	886293.Sinac_1580	7.153e-130	430.0	COG3356@1|root,COG3356@2|Bacteria,2IX5S@203682|Planctomycetes	203682|Planctomycetes	S	Neutral/alkaline non-lysosomal ceramidase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
CMS1_k127_1050446_2	1288963.ADIS_1774	1.685e-162	526.0	COG3356@1|root,COG3356@2|Bacteria,4NHP6@976|Bacteroidetes	976|Bacteroidetes	S	PFAM Neutral alkaline nonlysosomal ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1050446_11	344747.PM8797T_17127	3.142e-86	295.0	COG1413@1|root,COG1413@2|Bacteria,2IYWU@203682|Planctomycetes	203682|Planctomycetes	C	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CMS1_k127_1050446_10	344747.PM8797T_20783	7.496e-90	304.0	COG1082@1|root,COG1082@2|Bacteria,2IXXX@203682|Planctomycetes	203682|Planctomycetes	G	Xylose isomerase-like TIM barrel	-	-	5.1.3.22	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R03244	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	AP_endonuc_2
CMS1_k127_1050446_0	1121904.ARBP01000043_gene2130	3.106e-248	794.0	COG3661@1|root,COG3661@2|Bacteria,4PPN5@976|Bacteroidetes	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 67 family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1050446_19	1089553.Tph_c09580	1.622e-50	190.0	COG0639@1|root,COG0639@2|Bacteria,1UYWK@1239|Firmicutes,25DVG@186801|Clostridia,42IP1@68295|Thermoanaerobacterales	186801|Clostridia	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
CMS1_k127_1050446_18	644968.DFW101_1562	6.856e-52	198.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WIR4@28221|Deltaproteobacteria,2M7T3@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,Response_reg
CMS1_k127_1050446_20	518766.Rmar_2409	2.608e-47	175.0	COG0784@1|root,COG0784@2|Bacteria,4PNDD@976|Bacteroidetes,1FK5T@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS1_k127_1050446_12	595460.RRSWK_03276	1.716e-74	275.0	COG0642@1|root,COG2205@2|Bacteria,2J565@203682|Planctomycetes	203682|Planctomycetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
CMS1_k127_1050446_6	234267.Acid_5934	3.184e-132	430.0	COG0697@1|root,2Z7ID@2|Bacteria,3Y46C@57723|Acidobacteria	57723|Acidobacteria	EG	PFAM RhaT l-rhamnose-proton symport 2	-	-	-	ko:K02856	-	-	-	-	ko00000,ko02000	2.A.7.6	-	-	RhaT
CMS1_k127_1050446_1	595460.RRSWK_04637	1.7e-223	703.0	COG2407@1|root,COG2407@2|Bacteria,2J1YF@203682|Planctomycetes	203682|Planctomycetes	G	Catalyzes the conversion of L-arabinose to L-ribulose	-	-	5.3.1.4	ko:K01804	ko00040,ko01100,map00040,map01100	-	R01761	RC00516	ko00000,ko00001,ko01000	-	-	-	Arabinose_Isome
CMS1_k127_1050446_13	180332.JTGN01000022_gene1511	6.835e-73	258.0	COG0673@1|root,COG0673@2|Bacteria,1TQ72@1239|Firmicutes,24G9W@186801|Clostridia	186801|Clostridia	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_1050446_5	1195236.CTER_2031	1.363e-149	484.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,24G9G@186801|Clostridia	186801|Clostridia	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
CMS1_k127_1050446_23	1345023.M467_08880	1.162e-13	82.0	COG0697@1|root,COG0697@2|Bacteria,1UH2I@1239|Firmicutes,4HCFV@91061|Bacilli,3WFWS@539002|Bacillales incertae sedis	91061|Bacilli	EG	EamA-like transporter family	gmT1	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS1_k127_1050446_3	1177154.Y5S_00716	2.917e-154	504.0	COG0591@1|root,COG0591@2|Bacteria,1QUXM@1224|Proteobacteria,1T251@1236|Gammaproteobacteria,1XJTT@135619|Oceanospirillales	135619|Oceanospirillales	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
CMS1_k127_1050446_4	1303518.CCALI_00189	1.767e-153	502.0	COG2804@1|root,COG2804@2|Bacteria	2|Bacteria	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	gspE	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
CMS1_k127_1050446_14	858215.Thexy_1157	1.8e-68	248.0	COG1459@1|root,COG1459@2|Bacteria,1TQRZ@1239|Firmicutes,249FV@186801|Clostridia,42F7Z@68295|Thermoanaerobacterales	186801|Clostridia	U	PFAM Type II secretion system F domain	tapC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
CMS1_k127_1050446_22	1123371.ATXH01000016_gene1853	6.823e-35	141.0	COG2165@1|root,COG2165@2|Bacteria,2GIHW@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	NU	Type II secretion system (T2SS), protein G	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
CMS1_k127_1050446_26	1255043.TVNIR_1921	9.807e-05	51.0	COG4970@1|root,COG4970@2|Bacteria,1NBWI@1224|Proteobacteria,1S5MN@1236|Gammaproteobacteria,1WY85@135613|Chromatiales	135613|Chromatiales	U	General secretion pathway protein H	-	-	-	ko:K02457	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	GspH,N_methyl
CMS1_k127_1050446_28	1122613.ATUP01000001_gene1788	0.0003605	50.0	COG2165@1|root,COG2165@2|Bacteria,1NH8A@1224|Proteobacteria	1224|Proteobacteria	NU	General secretion pathway protein	lspI	-	-	ko:K02458	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSI
CMS1_k127_1050446_29	448385.sce9212	0.0005216	51.0	COG4795@1|root,COG4795@2|Bacteria,1NPEC@1224|Proteobacteria,42WZG@68525|delta/epsilon subdivisions,2WSPB@28221|Deltaproteobacteria,2YVMW@29|Myxococcales	28221|Deltaproteobacteria	U	Type II secretion system (T2SS), protein J	gspJ	-	-	ko:K02459	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSJ
CMS1_k127_1050446_24	521674.Plim_3639	4.311e-13	82.0	COG3156@1|root,COG3156@2|Bacteria,2IXHV@203682|Planctomycetes	203682|Planctomycetes	U	Type II secretion system (T2SS), protein K	-	-	-	-	-	-	-	-	-	-	-	-	T2SSK
CMS1_k127_1050446_27	768066.HELO_2772	0.0003259	51.0	2DKUH@1|root,30CV1@2|Bacteria,1NCRM@1224|Proteobacteria,1SBMH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	general secretion pathway protein	xpsM	-	-	ko:K02462	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSM_b
CMS1_k127_1050446_25	1121405.dsmv_0458	1.407e-12	77.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,42M9I@68525|delta/epsilon subdivisions,2WK1H@28221|Deltaproteobacteria,2MIEH@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	type II and III secretion system protein	gspD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
CMS1_k127_1053734_3	880070.Cycma_0177	3.865e-37	142.0	COG1621@1|root,COG1621@2|Bacteria,4P0AM@976|Bacteroidetes	976|Bacteroidetes	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1053734_1	180332.JTGN01000020_gene1191	3.554e-75	269.0	COG0407@1|root,COG0407@2|Bacteria,1W13C@1239|Firmicutes,24TPG@186801|Clostridia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
CMS1_k127_1053734_0	661478.OP10G_3071	1.84e-122	400.0	COG0492@1|root,COG0492@2|Bacteria	2|Bacteria	C	ferredoxin-NADP+ reductase activity	trxB	GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748	1.8.1.9	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000,ko03110	-	-	iNJ661.Rv3913	Pyr_redox_2,Thioredoxin
CMS1_k127_1053734_2	1267533.KB906743_gene813	2.027e-71	244.0	COG1082@1|root,COG1082@2|Bacteria,3Y3U5@57723|Acidobacteria,2JI4Y@204432|Acidobacteriia	204432|Acidobacteriia	G	AP endonuclease family 2 C terminus	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
CMS1_k127_105569_3	933262.AXAM01000031_gene3004	1.328e-06	51.0	COG1943@1|root,COG1943@2|Bacteria,1P19I@1224|Proteobacteria,42PP3@68525|delta/epsilon subdivisions,2WK0G@28221|Deltaproteobacteria,2MJPT@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
CMS1_k127_105569_1	926550.CLDAP_07110	8.339e-97	328.0	COG0457@1|root,COG0457@2|Bacteria,2G76G@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF4037)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4037
CMS1_k127_105569_2	32049.SYNPCC7002_A2303	4.546e-26	118.0	COG0265@1|root,COG0265@2|Bacteria,1G0U4@1117|Cyanobacteria,1GYHE@1129|Synechococcus	1117|Cyanobacteria	O	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	hhoB	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
CMS1_k127_105569_0	886293.Sinac_3826	1.562e-164	531.0	COG3518@1|root,COG3518@2|Bacteria,2J26H@203682|Planctomycetes	203682|Planctomycetes	S	anti-sigma factor antagonist activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_105870_2	479432.Sros_3086	2.452e-06	51.0	COG0001@1|root,COG0001@2|Bacteria,2IBG2@201174|Actinobacteria,4ENJ2@85012|Streptosporangiales	201174|Actinobacteria	H	Aminotransferase class-III	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CMS1_k127_105870_0	1267535.KB906767_gene1674	1.794e-172	575.0	COG1331@1|root,COG1331@2|Bacteria	2|Bacteria	O	Highly conserved protein containing a thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4861,Glyco_hydro_76
CMS1_k127_105870_3	368407.Memar_0673	1.611e-05	57.0	arCOG02521@1|root,arCOG02537@1|root,arCOG02521@2157|Archaea,arCOG02537@2157|Archaea	2157|Archaea	E	Glycoside hydrolase family 28	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_105870_1	1122605.KB893625_gene1928	3.132e-07	64.0	2AF40@1|root,3152Q@2|Bacteria,4P1UF@976|Bacteroidetes,1IX0U@117747|Sphingobacteriia	976|Bacteroidetes	S	Heparinase II/III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III
CMS1_k127_1063753_5	1449063.JMLS01000019_gene5730	1.739e-42	159.0	COG3682@1|root,COG3682@2|Bacteria,1V7EY@1239|Firmicutes,4HIKG@91061|Bacilli,26YMQ@186822|Paenibacillaceae	91061|Bacilli	K	Penicillinase repressor	blaI	-	-	ko:K02171,ko:K02546	ko01501,map01501	M00625,M00627	-	-	ko00000,ko00001,ko00002,ko01504,ko03000	-	-	-	Penicillinase_R
CMS1_k127_1063753_1	555088.DealDRAFT_2020	4.309e-62	246.0	COG4219@1|root,COG4219@2|Bacteria,1TP3Z@1239|Firmicutes,249NV@186801|Clostridia,42KY1@68298|Syntrophomonadaceae	186801|Clostridia	KT	PFAM peptidase M56 BlaR1	blaR	-	-	ko:K02172	ko01501,map01501	M00627	-	-	ko00000,ko00001,ko00002,ko01002,ko01504	-	-	-	NAGPA,Peptidase_M56
CMS1_k127_1063753_3	1123242.JH636434_gene5196	3.401e-47	197.0	COG4219@1|root,COG4219@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	Amidase_6,CarboxypepD_reg,LysM,PD40,Peptidase_M23,Peptidase_M56,SBP_bac_10
CMS1_k127_1063753_6	292563.Cyast_1518	5.326e-38	149.0	COG0454@1|root,COG0454@2|Bacteria,1GHC8@1117|Cyanobacteria	1117|Cyanobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	ko:K03830	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_10
CMS1_k127_1063753_0	1123242.JH636435_gene2637	3.646e-104	353.0	COG0613@1|root,COG0613@2|Bacteria,2IX3G@203682|Planctomycetes	203682|Planctomycetes	S	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1063753_2	504487.JCM19302_3630	5.563e-54	213.0	2DBT1@1|root,2ZAV2@2|Bacteria,4NK57@976|Bacteroidetes,1IA5N@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1063753_7	1123242.JH636434_gene5120	1.692e-16	94.0	COG2151@1|root,COG2151@2|Bacteria	2|Bacteria	L	metal-sulfur cluster biosynthetic enzyme	-	-	-	ko:K02612	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FeS_assembly_P
CMS1_k127_1068906_6	1380386.JIAW01000012_gene1852	1.539e-14	87.0	COG3391@1|root,COG3693@1|root,COG4932@1|root,COG3391@2|Bacteria,COG3693@2|Bacteria,COG4932@2|Bacteria,2GK45@201174|Actinobacteria,2366T@1762|Mycobacteriaceae	201174|Actinobacteria	M	40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase,Lactonase
CMS1_k127_1068906_1	344747.PM8797T_25940	1.272e-202	651.0	COG1523@1|root,COG1523@2|Bacteria,2IXJM@203682|Planctomycetes	203682|Planctomycetes	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
CMS1_k127_1068906_7	748280.NH8B_1354	1.329e-12	78.0	COG0673@1|root,COG0673@2|Bacteria,1NKUI@1224|Proteobacteria,2VUT6@28216|Betaproteobacteria,2KTQX@206351|Neisseriales	206351|Neisseriales	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_1068906_9	644282.Deba_0927	7.579e-10	70.0	COG0308@1|root,COG0308@2|Bacteria,1NJK3@1224|Proteobacteria,42Y4Q@68525|delta/epsilon subdivisions,2WTET@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	aminopeptidase N	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2
CMS1_k127_1068906_3	1120973.AQXL01000133_gene1840	6.709e-110	395.0	COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,4HA64@91061|Bacilli,277XR@186823|Alicyclobacillaceae	91061|Bacilli	L	ATP-dependent helicase nuclease subunit A	-	-	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
CMS1_k127_1068906_4	1123242.JH636437_gene6085	5.069e-63	247.0	COG3857@1|root,COG3857@2|Bacteria,2IZEK@203682|Planctomycetes	203682|Planctomycetes	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	AAA_19,Exonuc_V_gamma,PDDEXK_1,UvrD_C
CMS1_k127_1068906_0	903818.KI912268_gene2932	7.951e-221	699.0	COG1061@1|root,COG1061@2|Bacteria	2|Bacteria	L	Type III restriction enzyme res subunit	ercc3	-	3.6.4.12	ko:K10843	ko03022,ko03420,map03022,map03420	M00290	-	-	ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	ERCC3_RAD25_C,Helicase_C_3,ResIII
CMS1_k127_1068906_2	575540.Isop_2875	2.635e-121	398.0	COG4864@1|root,COG4864@2|Bacteria,2IXDK@203682|Planctomycetes	203682|Planctomycetes	S	UPF0365 protein	-	-	-	-	-	-	-	-	-	-	-	-	YdfA_immunity
CMS1_k127_1068906_8	411465.PEPMIC_01348	2.25e-10	69.0	COG4864@1|root,COG4864@2|Bacteria,1TPTD@1239|Firmicutes,24APU@186801|Clostridia,22G2G@1570339|Peptoniphilaceae	186801|Clostridia	S	UPF0365 protein	-	-	-	-	-	-	-	-	-	-	-	-	YdfA_immunity
CMS1_k127_1068906_5	1122223.KB890688_gene1781	2.458e-17	87.0	COG1030@1|root,COG1030@2|Bacteria,1WIAJ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	Membrane-bound serine protease (ClpP class)	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD,SDH_sah
CMS1_k127_108936_12	1210884.HG799466_gene12640	2.347e-77	261.0	COG1621@1|root,COG1621@2|Bacteria,2IY26@203682|Planctomycetes	203682|Planctomycetes	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_108936_1	1340493.JNIF01000003_gene4723	9.389e-167	541.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	3.1.6.1,3.1.6.8	ko:K01130,ko:K01134	ko00140,ko00600,ko04142,map00140,map00600,map04142	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	DUF4976,Sulfatase
CMS1_k127_108936_8	404589.Anae109_3433	3.372e-106	356.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WJ28@28221|Deltaproteobacteria,2YWA0@29|Myxococcales	28221|Deltaproteobacteria	NU	Type II/IV secretion system protein	pilT-1	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
CMS1_k127_108936_22	439235.Dalk_5142	4.558e-06	59.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,42PFW@68525|delta/epsilon subdivisions,2WJ1N@28221|Deltaproteobacteria,2MI4U@213118|Desulfobacterales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
CMS1_k127_108936_6	247490.KSU1_B0685	4.146e-107	360.0	COG0304@1|root,COG0304@2|Bacteria,2IWRA@203682|Planctomycetes	2|Bacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
CMS1_k127_108936_5	477974.Daud_0675	1.497e-110	389.0	COG2203@1|root,COG3852@1|root,COG2203@2|Bacteria,COG3852@2|Bacteria,1TRH0@1239|Firmicutes,25F8J@186801|Clostridia,2673W@186807|Peptococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9
CMS1_k127_108936_17	477974.Daud_0675	2.624e-44	183.0	COG2203@1|root,COG3852@1|root,COG2203@2|Bacteria,COG3852@2|Bacteria,1TRH0@1239|Firmicutes,25F8J@186801|Clostridia,2673W@186807|Peptococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9
CMS1_k127_108936_4	1121422.AUMW01000045_gene1208	4.504e-111	379.0	COG2204@1|root,COG2204@2|Bacteria,1VSKG@1239|Firmicutes,24ZP4@186801|Clostridia,2646G@186807|Peptococcaceae	186801|Clostridia	T	Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS1_k127_108936_9	215803.DB30_0502	2.03e-105	351.0	COG0524@1|root,COG0524@2|Bacteria,1Q8Y3@1224|Proteobacteria,42NSV@68525|delta/epsilon subdivisions,2WJWD@28221|Deltaproteobacteria,2YU0F@29|Myxococcales	28221|Deltaproteobacteria	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_2683	PfkB
CMS1_k127_108936_2	390874.Tpet_1677	1.928e-123	419.0	COG0747@1|root,COG0747@2|Bacteria,2GCNZ@200918|Thermotogae	200918|Thermotogae	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_108936_0	886293.Sinac_2586	1.52e-184	599.0	COG0405@1|root,COG0405@2|Bacteria,2IY9Q@203682|Planctomycetes	203682|Planctomycetes	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
CMS1_k127_108936_7	926569.ANT_25080	1.301e-106	355.0	COG0667@1|root,COG0667@2|Bacteria,2G6BF@200795|Chloroflexi	200795|Chloroflexi	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS1_k127_108936_3	595460.RRSWK_04041	1.048e-116	388.0	COG0714@1|root,COG0714@2|Bacteria,2IX1F@203682|Planctomycetes	203682|Planctomycetes	S	ATPase associated with	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS1_k127_108936_18	1379698.RBG1_1C00001G0608	8.874e-41	163.0	COG0515@1|root,COG5616@1|root,COG0515@2|Bacteria,COG5616@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08282,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_16,TPR_2,TPR_8,TolB_N
CMS1_k127_108936_21	484770.UFO1_1573	3.04e-18	97.0	COG1376@1|root,COG1376@2|Bacteria,1TQAB@1239|Firmicutes,4H267@909932|Negativicutes	909932|Negativicutes	S	ErfK YbiS YcfS YnhG	erfK	-	-	-	-	-	-	-	-	-	-	-	YkuD
CMS1_k127_108936_13	1121918.ARWE01000001_gene2959	6.844e-64	239.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42T0Q@68525|delta/epsilon subdivisions,2WUA0@28221|Deltaproteobacteria,43SZX@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GAF_2,GGDEF,Response_reg
CMS1_k127_108936_10	443143.GM18_1770	4.593e-104	347.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,42M46@68525|delta/epsilon subdivisions,2WJ7G@28221|Deltaproteobacteria,43TBH@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the conversion of dihydroorotate to orotate with NAD( ) as electron acceptor	pyrD	GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.1.14,1.3.5.2	ko:K00254,ko:K02823,ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01868,R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
CMS1_k127_108936_15	118005.AWNK01000005_gene1434	2.609e-52	192.0	COG0284@1|root,COG0284@2|Bacteria	2|Bacteria	F	orotidine-5'-phosphate decarboxylase activity	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	iECO103_1326.ECO103_1444,iECSF_1327.ECSF_1264,iSFV_1184.SFV_1294,iSF_1195.SF1285,iSFxv_1172.SFxv_1457,iS_1188.S1368,ic_1306.c1750	OMPdecase
CMS1_k127_108936_14	1122947.FR7_3880	1.451e-52	194.0	COG0461@1|root,COG0461@2|Bacteria,1V1BZ@1239|Firmicutes,4H2G4@909932|Negativicutes	909932|Negativicutes	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
CMS1_k127_108936_11	717605.Theco_0497	6.972e-78	275.0	COG1486@1|root,COG1486@2|Bacteria,1TQ9I@1239|Firmicutes,4H9Z4@91061|Bacilli,26QIP@186822|Paenibacillaceae	91061|Bacilli	G	Catalyzes the fromation of N-acetyl-D-glucosamine and N-acetyl-D-glucosamine-6-phosphate from diacetylchitobiose-6-phosphate	celF	-	3.2.1.122,3.2.1.86	ko:K01222,ko:K01232	ko00010,ko00500,map00010,map00500	-	R00837,R00838,R00839,R05133,R05134,R06113	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GH4,GT4	-	Glyco_hydro_4,Glyco_hydro_4C
CMS1_k127_108936_23	180281.CPCC7001_1598	3.03e-05	56.0	COG1413@1|root,COG1413@2|Bacteria,1G600@1117|Cyanobacteria,22SSN@167375|Cyanobium	1117|Cyanobacteria	C	PBS lyase HEAT-like repeat	cpcF	-	4.4.1.32	ko:K02289	ko00196,ko01100,map00196,map01100	-	-	-	ko00000,ko00001,ko00194,ko01000	-	-	-	HEAT_2,HEAT_PBS
CMS1_k127_108936_20	1173026.Glo7428_2148	5.488e-19	89.0	COG1254@1|root,COG1254@2|Bacteria,1G7UW@1117|Cyanobacteria	1117|Cyanobacteria	C	Belongs to the acylphosphatase family	acyP	GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
CMS1_k127_108936_16	1200792.AKYF01000013_gene4274	4.097e-46	176.0	COG2227@1|root,COG2227@2|Bacteria,1UHU9@1239|Firmicutes,4HXCZ@91061|Bacilli,274IH@186822|Paenibacillaceae	91061|Bacilli	H	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS1_k127_108936_19	1206735.BAGG01000049_gene2068	1.461e-38	156.0	COG0657@1|root,COG0657@2|Bacteria,2GTEV@201174|Actinobacteria,4FWNU@85025|Nocardiaceae	201174|Actinobacteria	I	Prolyl oligopeptidase family	-	-	3.1.1.3	ko:K01046	ko00561,ko01100,map00561,map01100	M00098	R02250,R02687	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_3
CMS1_k127_1095750_1	1125863.JAFN01000001_gene3085	4.543e-21	99.0	COG2206@1|root,COG2206@2|Bacteria,1R53C@1224|Proteobacteria,42R7P@68525|delta/epsilon subdivisions,2WMSW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	metal-dependent phosphohydrolase HD region	-	-	-	-	-	-	-	-	-	-	-	-	HD
CMS1_k127_1095750_0	997346.HMPREF9374_0249	2.622e-79	287.0	COG1472@1|root,COG1472@2|Bacteria,1TP63@1239|Firmicutes,4HBDB@91061|Bacilli,27CNY@186824|Thermoactinomycetaceae	91061|Bacilli	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3,Glyco_hydro_3_C
CMS1_k127_1109136_2	1278073.MYSTI_03939	1.081e-13	84.0	COG0793@1|root,COG4932@1|root,COG0793@2|Bacteria,COG4932@2|Bacteria,1Q2N3@1224|Proteobacteria,4388W@68525|delta/epsilon subdivisions,2XA2N@28221|Deltaproteobacteria,2YXAB@29|Myxococcales	28221|Deltaproteobacteria	M	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,PDZ_2
CMS1_k127_1109136_0	56780.SYN_00323	1.185e-133	436.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,1MY9R@1224|Proteobacteria,42R1V@68525|delta/epsilon subdivisions,2WN7S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Belongs to the peptidase M50B family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50,Peptidase_M50B
CMS1_k127_1109136_1	1125701.HMPREF1221_01616	3.477e-39	160.0	COG2407@1|root,COG2407@2|Bacteria	2|Bacteria	G	Converts the aldose L-fucose into the corresponding ketose L-fuculose	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1111071_1	218284.CCDN010000001_gene445	2.212e-09	70.0	COG4932@1|root,COG4932@2|Bacteria,1TQBI@1239|Firmicutes,4HBAT@91061|Bacilli,1ZD6Z@1386|Bacillus	91061|Bacilli	M	cell wall anchor domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Cna_B,Collagen_bind,Gram_pos_anchor,MucBP
CMS1_k127_1111071_0	1288963.ADIS_0880	1.265e-34	138.0	COG3119@1|root,COG3119@2|Bacteria,4NEPB@976|Bacteroidetes,47MYW@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS1_k127_1126285_1	706434.HMPREF9429_01218	8.189e-88	295.0	COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,4H327@909932|Negativicutes	909932|Negativicutes	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
CMS1_k127_1126285_3	1120746.CCNL01000012_gene1932	5.181e-24	106.0	COG0799@1|root,COG0799@2|Bacteria	2|Bacteria	S	negative regulation of ribosome biogenesis	rsfS	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113	2.7.7.18	ko:K00969,ko:K09710	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000,ko03009	-	-	-	RsfS
CMS1_k127_1126285_2	263820.PTO0135	7.564e-44	170.0	COG0515@1|root,arCOG03682@2157|Archaea,2XWZP@28890|Euryarchaeota	28890|Euryarchaeota	T	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	NosD,Pkinase
CMS1_k127_1126285_0	1379698.RBG1_1C00001G0443	4.93e-217	681.0	COG1866@1|root,COG1866@2|Bacteria,2NQI3@2323|unclassified Bacteria	2|Bacteria	C	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005488,GO:0005509,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0017076,GO:0019318,GO:0019319,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS09060,iSF_1195.SF3422,iUTI89_1310.UTI89_C3903,iYO844.BSU30560	PEPCK_ATP
CMS1_k127_1126374_11	663932.KB902575_gene412	8.635e-08	58.0	COG2071@1|root,COG2071@2|Bacteria,1MV8E@1224|Proteobacteria,2VG90@28211|Alphaproteobacteria,2JYRN@204441|Rhodospirillales	204441|Rhodospirillales	S	Peptidase C26	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
CMS1_k127_1126374_9	506534.Rhein_1995	8.452e-36	152.0	COG0845@1|root,COG0845@2|Bacteria,1MX0G@1224|Proteobacteria,1RN0S@1236|Gammaproteobacteria,1X2DY@135613|Chromatiales	135613|Chromatiales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
CMS1_k127_1126374_1	1336233.JAEH01000009_gene2809	3.44e-206	685.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,1RMBN@1236|Gammaproteobacteria,2Q9NW@267890|Shewanellaceae	1236|Gammaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	mdtB	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
CMS1_k127_1126374_2	880073.Calab_1196	6.859e-175	588.0	COG0841@1|root,COG0841@2|Bacteria,2NNUH@2323|unclassified Bacteria	2|Bacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
CMS1_k127_1126374_6	316067.Geob_2899	3.606e-84	286.0	COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,42MIF@68525|delta/epsilon subdivisions,2WIQF@28221|Deltaproteobacteria,43T81@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
CMS1_k127_1126374_12	1167006.UWK_00785	1.029e-05	55.0	COG1314@1|root,COG1314@2|Bacteria,1NJ1D@1224|Proteobacteria,42TKW@68525|delta/epsilon subdivisions,2WRA3@28221|Deltaproteobacteria,2MKYR@213118|Desulfobacterales	28221|Deltaproteobacteria	U	PFAM Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
CMS1_k127_1126374_3	314345.SPV1_08191	1.474e-137	452.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria	1224|Proteobacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
CMS1_k127_1126374_4	218284.CCDN010000006_gene3642	5.89e-118	393.0	COG0141@1|root,COG0141@2|Bacteria,1TPAW@1239|Firmicutes,4H9XK@91061|Bacilli,1ZCAX@1386|Bacillus	91061|Bacilli	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU34910	Histidinol_dh
CMS1_k127_1126374_5	237368.SCABRO_00778	3.71e-91	316.0	COG0079@1|root,COG0079@2|Bacteria,2IWYA@203682|Planctomycetes	203682|Planctomycetes	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS1_k127_1126374_8	443143.GM18_3478	5.351e-46	177.0	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,42MBR@68525|delta/epsilon subdivisions,2WJ0Z@28221|Deltaproteobacteria,43SFX@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	PFAM peptidase M48 Ste24p	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_1238	Peptidase_M48,TPR_14,TPR_16,TPR_19
CMS1_k127_1126374_0	1125863.JAFN01000001_gene210	0.0	1194.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,42NDJ@68525|delta/epsilon subdivisions,2WJSH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
CMS1_k127_1126374_7	523791.Kkor_2606	1.589e-60	239.0	COG3210@1|root,COG3210@2|Bacteria,1QUXB@1224|Proteobacteria,1SUAH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1126374_10	886293.Sinac_7034	9.421e-34	151.0	COG4625@1|root,COG4625@2|Bacteria,2J0EF@203682|Planctomycetes	2|Bacteria	S	Bacterial Ig-like domain (group 3)	-	-	3.4.21.50	ko:K01337,ko:K20276,ko:K21449	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko02000	1.B.40.2	-	-	Autotransporter,Big_3_5,Cadherin-like,Calx-beta,DUF4347,He_PIG,PATR,TIG,fn3
CMS1_k127_1139324_4	1047013.AQSP01000109_gene2431	4.661e-26	126.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1139324_2	644548.SCNU_06680	6.084e-41	168.0	COG0515@1|root,COG0515@2|Bacteria,2GNT2@201174|Actinobacteria,4GCXB@85026|Gordoniaceae	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Lpp-LpqN,Pkinase
CMS1_k127_1139324_5	555079.Toce_1930	1.418e-22	112.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,247KA@186801|Clostridia,42FCP@68295|Thermoanaerobacterales	186801|Clostridia	NU	PFAM Type II secretion system protein E	pilB	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
CMS1_k127_1139324_0	583355.Caka_0543	1.99e-150	489.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	yegT	-	-	ko:K05820	-	-	-	-	ko00000,ko02000	2.A.1.27	-	-	Nuc_H_symport
CMS1_k127_1139324_3	761193.Runsl_2945	3.128e-34	142.0	COG3350@1|root,COG3350@2|Bacteria,4NRFU@976|Bacteroidetes,47QIJ@768503|Cytophagia	976|Bacteroidetes	S	monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	YHS
CMS1_k127_1139324_1	880070.Cycma_1815	3.411e-42	165.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA,AhpC-TSA_2
CMS1_k127_1142710_17	338966.Ppro_2642	1.434e-31	129.0	COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,42QQP@68525|delta/epsilon subdivisions,2WMZE@28221|Deltaproteobacteria,43UMJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
CMS1_k127_1142710_6	1460640.JCM19046_4477	3.835e-118	394.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,4HAJ6@91061|Bacilli,1ZAUP@1386|Bacillus	91061|Bacilli	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
CMS1_k127_1142710_18	497964.CfE428DRAFT_2007	1.387e-29	125.0	COG0558@1|root,COG0558@2|Bacteria,46T66@74201|Verrucomicrobia	74201|Verrucomicrobia	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
CMS1_k127_1142710_19	246194.CHY_2047	1.421e-26	116.0	COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,25AZ2@186801|Clostridia,42JDU@68295|Thermoanaerobacterales	186801|Clostridia	K	Response regulator receiver	phoB	-	-	ko:K02483,ko:K07658,ko:K07668	ko02020,map02020	M00434,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_1142710_16	1267535.KB906767_gene3313	1.673e-32	148.0	COG1874@1|root,COG1874@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4832,GHL6,Glyco_hydro_42,Glyco_hydro_42M
CMS1_k127_1142710_5	278963.ATWD01000001_gene3347	7.416e-145	473.0	COG5434@1|root,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBM-like,F5_F8_type_C,Pectate_lyase_3
CMS1_k127_1142710_24	1301100.HG529431_gene1823	1.96e-06	59.0	COG4969@1|root,COG4969@2|Bacteria,1UI23@1239|Firmicutes,25EXE@186801|Clostridia	186801|Clostridia	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
CMS1_k127_1142710_2	1125863.JAFN01000001_gene2631	3.879e-164	541.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,42MKU@68525|delta/epsilon subdivisions,2WJR3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM UvrD REP helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
CMS1_k127_1142710_7	338966.Ppro_1345	4.124e-107	359.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1MU60@1224|Proteobacteria,42MGN@68525|delta/epsilon subdivisions,2WJET@28221|Deltaproteobacteria,43T0C@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	amino acid-binding ACT domain protein	pheA	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
CMS1_k127_1142710_13	756272.Plabr_4506	1.119e-43	171.0	COG0652@1|root,COG0652@2|Bacteria,2IZWK@203682|Planctomycetes	203682|Planctomycetes	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03767	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
CMS1_k127_1142710_11	1429916.X566_21020	1.135e-61	218.0	COG0652@1|root,COG0652@2|Bacteria	2|Bacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	-	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
CMS1_k127_1142710_9	649638.Trad_0849	1.438e-82	286.0	COG0673@1|root,COG0673@2|Bacteria,1WJSV@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_1142710_20	620914.JH621283_gene188	1.433e-18	95.0	COG0454@1|root,COG0456@2|Bacteria,4NSM6@976|Bacteroidetes,1I41U@117743|Flavobacteriia	976|Bacteroidetes	K	acetyltransferase	yitI	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_3
CMS1_k127_1142710_10	765952.PUV_02630	8.724e-72	256.0	COG1024@1|root,COG1024@2|Bacteria,2JGC4@204428|Chlamydiae	204428|Chlamydiae	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.18	ko:K13766	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS1_k127_1142710_15	716544.wcw_0449	3e-33	133.0	2CIU6@1|root,32S8H@2|Bacteria,2JGEN@204428|Chlamydiae	204428|Chlamydiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1142710_3	765952.PUV_02650	2.016e-161	523.0	COG3185@1|root,COG3185@2|Bacteria,2JFPQ@204428|Chlamydiae	204428|Chlamydiae	E	Pfam:DUF1446	-	-	-	-	-	-	-	-	-	-	-	-	AtuA
CMS1_k127_1142710_0	765952.PUV_02690	8.159e-227	714.0	COG4799@1|root,COG4799@2|Bacteria,2JFTC@204428|Chlamydiae	204428|Chlamydiae	I	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
CMS1_k127_1142710_1	765952.PUV_02700	1.458e-211	672.0	COG1960@1|root,COG1960@2|Bacteria,2JFR3@204428|Chlamydiae	204428|Chlamydiae	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS1_k127_1142710_4	264732.Moth_1072	5.576e-159	531.0	COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,247KM@186801|Clostridia,42EM0@68295|Thermoanaerobacterales	186801|Clostridia	D	PFAM cell divisionFtsK SpoIIIE	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
CMS1_k127_1142710_23	940282.CADQ01000101_gene1673	1.292e-09	65.0	COG1426@1|root,COG1426@2|Bacteria,1MYWX@1224|Proteobacteria,2U8C2@28211|Alphaproteobacteria,2JZQ1@204441|Rhodospirillales	204441|Rhodospirillales	S	Domain of unknown function (DUF4115)	-	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25
CMS1_k127_1142710_14	1396418.BATQ01000155_gene2497	1.283e-33	138.0	COG0558@1|root,COG0558@2|Bacteria,46VZY@74201|Verrucomicrobia,2IUG1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
CMS1_k127_1142710_8	1304880.JAGB01000001_gene311	5.185e-96	328.0	COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,2480T@186801|Clostridia	186801|Clostridia	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
CMS1_k127_1142710_22	1125712.HMPREF1316_1222	2.43e-13	78.0	COG3688@1|root,COG3688@2|Bacteria,2HUV5@201174|Actinobacteria,4CVRA@84998|Coriobacteriia	84998|Coriobacteriia	S	YacP-like NYN domain	-	-	-	ko:K06962	-	-	-	-	ko00000	-	-	-	NYN_YacP
CMS1_k127_1142710_21	926569.ANT_03680	8.495e-15	84.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
CMS1_k127_1142710_12	452471.Aasi_0363	2.687e-47	195.0	COG0666@1|root,COG4908@1|root,COG0666@2|Bacteria,COG4908@2|Bacteria,4NEYY@976|Bacteroidetes,47MVD@768503|Cytophagia	976|Bacteroidetes	U	Ankyrin repeats (3 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_3,Ank_4,Ank_5,SHOCT,SecA_DEAD
CMS1_k127_1152498_2	485913.Krac_1276	6.504e-41	158.0	COG2159@1|root,COG2159@2|Bacteria,2G8DN@200795|Chloroflexi	200795|Chloroflexi	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
CMS1_k127_1152498_3	760568.Desku_0341	4.791e-35	139.0	COG2030@1|root,COG2030@2|Bacteria,1V8MB@1239|Firmicutes,24WTT@186801|Clostridia,2639K@186807|Peptococcaceae	186801|Clostridia	I	PFAM MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
CMS1_k127_1152498_5	760568.Desku_0340	2.332e-25	110.0	COG2030@1|root,COG2030@2|Bacteria	2|Bacteria	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N,MaoC_dehydratas
CMS1_k127_1152498_1	76114.ebA5300	2.13e-73	261.0	COG1028@1|root,COG1028@2|Bacteria,1N907@1224|Proteobacteria,2VJ81@28216|Betaproteobacteria,2KYAR@206389|Rhodocyclales	206389|Rhodocyclales	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS1_k127_1152498_0	556263.FSEG_00593	1.646e-103	351.0	COG0427@1|root,COG0427@2|Bacteria,378P8@32066|Fusobacteria	32066|Fusobacteria	C	Acetyl-CoA hydrolase/transferase C-terminal domain	cat	-	-	ko:K18122	ko00650,ko01100,ko01200,map00650,map01100,map01200	-	R05336	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
CMS1_k127_1152498_4	322710.Avin_20920	3.082e-27	118.0	COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,1RS29@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EQ	Hydantoinase B/oxoprolinase	-	-	3.5.2.14,6.4.1.6	ko:K01474,ko:K10854	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
CMS1_k127_1155141_12	237368.SCABRO_03331	5.664e-18	97.0	COG0706@1|root,COG0706@2|Bacteria,2IYA0@203682|Planctomycetes	203682|Planctomycetes	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,PDZ_2,YidC_periplas
CMS1_k127_1155141_10	519989.ECTPHS_07611	6.362e-25	105.0	COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria	1224|Proteobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	yidD	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
CMS1_k127_1155141_14	1121430.JMLG01000002_gene1322	2.182e-16	83.0	COG0594@1|root,COG0594@2|Bacteria,1VA78@1239|Firmicutes,24QK5@186801|Clostridia	186801|Clostridia	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
CMS1_k127_1155141_15	1122164.JHWF01000003_gene2152	3.568e-13	70.0	COG0230@1|root,COG0230@2|Bacteria,1NGGS@1224|Proteobacteria,1SGDJ@1236|Gammaproteobacteria,1JF92@118969|Legionellales	118969|Legionellales	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
CMS1_k127_1155141_6	414684.RC1_3043	1.401e-56	203.0	COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,2U7B5@28211|Alphaproteobacteria,2JS8T@204441|Rhodospirillales	204441|Rhodospirillales	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
CMS1_k127_1155141_4	1430331.EP10_17220	1.057e-100	346.0	COG0612@1|root,COG0612@2|Bacteria,1TP5I@1239|Firmicutes,4HBBF@91061|Bacilli,1WEV9@129337|Geobacillus	91061|Bacilli	S	Belongs to the peptidase M16 family	mlpA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
CMS1_k127_1155141_0	269799.Gmet_1591	4.27e-232	741.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,42MTZ@68525|delta/epsilon subdivisions,2WJCE@28221|Deltaproteobacteria,43TFC@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
CMS1_k127_1155141_8	471875.RUMLAC_01779	2.219e-30	122.0	COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,24MRM@186801|Clostridia,3WK6U@541000|Ruminococcaceae	186801|Clostridia	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
CMS1_k127_1155141_3	1234664.AMRO01000028_gene1509	1.061e-145	472.0	COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,4H9R3@91061|Bacilli,1WEDT@129337|Geobacillus	91061|Bacilli	F	Belongs to the phosphoglycerate kinase family	pgk	GO:0001871,GO:0002020,GO:0003674,GO:0003824,GO:0004618,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009893,GO:0009986,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019222,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030162,GO:0030193,GO:0030195,GO:0030246,GO:0030247,GO:0030312,GO:0031323,GO:0031325,GO:0032101,GO:0032102,GO:0032268,GO:0032270,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043532,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0045862,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050818,GO:0050819,GO:0050878,GO:0051171,GO:0051173,GO:0051186,GO:0051188,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051917,GO:0051919,GO:0055086,GO:0060255,GO:0061041,GO:0061045,GO:0065007,GO:0065008,GO:0070613,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0080134,GO:0090407,GO:1900046,GO:1900047,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903034,GO:1903035,GO:1903317,GO:1903319,GO:2001065	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iSB619.SA_RS04145	PGK
CMS1_k127_1155141_2	880073.Calab_3781	1.083e-153	492.0	COG0057@1|root,COG0057@2|Bacteria,2NNPP@2323|unclassified Bacteria	2|Bacteria	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
CMS1_k127_1155141_9	1304888.ATWF01000001_gene728	5.668e-25	111.0	COG2050@1|root,COG2050@2|Bacteria,2GFTJ@200930|Deferribacteres	200930|Deferribacteres	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
CMS1_k127_1155141_17	765910.MARPU_15255	1.536e-06	58.0	COG3218@1|root,COG3218@2|Bacteria,1N13E@1224|Proteobacteria,1S663@1236|Gammaproteobacteria,1WYRS@135613|Chromatiales	135613|Chromatiales	S	ABC-type transport auxiliary lipoprotein component	-	-	-	ko:K18480	-	M00669	-	-	ko00000,ko00002,ko02000	3.A.1.27.1	-	-	ABC_trans_aux
CMS1_k127_1155141_16	1231391.AMZF01000065_gene1056	8.844e-11	73.0	COG1463@1|root,COG1463@2|Bacteria,1MU4B@1224|Proteobacteria,2VKNH@28216|Betaproteobacteria,3T8X7@506|Alcaligenaceae	28216|Betaproteobacteria	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
CMS1_k127_1155141_5	880073.Calab_1080	2.867e-79	271.0	COG1127@1|root,COG1127@2|Bacteria,2NP3U@2323|unclassified Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, ATPase component	ttg2A	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
CMS1_k127_1155141_7	880073.Calab_1079	7.691e-49	188.0	COG0767@1|root,COG0767@2|Bacteria,2NPFZ@2323|unclassified Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents permease component	mlaE_1	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE,STAS_2
CMS1_k127_1155141_1	886293.Sinac_2587	1.727e-208	668.0	COG0272@1|root,COG0272@2|Bacteria,2IXIC@203682|Planctomycetes	203682|Planctomycetes	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
CMS1_k127_1155141_13	209285.XP_006693556.1	8.964e-18	86.0	COG1012@1|root,KOG2450@2759|Eukaryota,39RV1@33154|Opisthokonta,3NUPB@4751|Fungi,3QQVQ@4890|Ascomycota,213WT@147550|Sordariomycetes,3U8U4@5139|Sordariales,3HBXV@35718|Chaetomiaceae	4751|Fungi	C	Belongs to the aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
CMS1_k127_1159314_2	234267.Acid_5559	3.507e-33	132.0	COG3250@1|root,COG3408@1|root,COG3250@2|Bacteria,COG3408@2|Bacteria,3Y2YG@57723|Acidobacteria	57723|Acidobacteria	G	Bacterial alpha-L-rhamnosidase C-terminal domain	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
CMS1_k127_1159314_0	1195236.CTER_2499	5.376e-317	990.0	COG0383@1|root,COG0383@2|Bacteria,1TQEH@1239|Firmicutes,248VH@186801|Clostridia,3WHH3@541000|Ruminococcaceae	186801|Clostridia	G	PFAM Glycosyl hydrolases family 38 C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
CMS1_k127_1159314_1	644282.Deba_2761	4.961e-40	154.0	COG1983@1|root,COG1983@2|Bacteria,1PWDN@1224|Proteobacteria,42TA8@68525|delta/epsilon subdivisions,2WPVU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KT	PspC domain protein	pspC	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	PspC
CMS1_k127_1171721_3	926550.CLDAP_31570	2.096e-112	369.0	COG0673@1|root,COG0673@2|Bacteria,2G6KB@200795|Chloroflexi	200795|Chloroflexi	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_1171721_4	439235.Dalk_2235	1.912e-103	345.0	COG0863@1|root,COG0863@2|Bacteria	2|Bacteria	L	N-4 methylation of cytosine	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase
CMS1_k127_1171721_6	314230.DSM3645_13183	9.825e-60	215.0	COG2908@1|root,COG2908@2|Bacteria,2J0XK@203682|Planctomycetes	203682|Planctomycetes	S	Calcineurin-like phosphoesterase	-	-	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Metallophos
CMS1_k127_1171721_5	1306947.ARQD01000001_gene656	3.886e-73	261.0	COG2515@1|root,COG2515@2|Bacteria,2NP9B@2323|unclassified Bacteria	2|Bacteria	E	Pyridoxal-phosphate dependent enzyme	dcyD	-	3.5.99.7,4.4.1.15,5.1.1.14	ko:K01505,ko:K05396,ko:K19105	ko00261,ko00270,ko01130,map00261,map00270,map01130	M00736	R00997,R01874,R03073,R10883	RC00302,RC00382,RC00419	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS1_k127_1171721_7	204669.Acid345_1629	5.764e-20	95.0	2D0AC@1|root,32T87@2|Bacteria,3Y56N@57723|Acidobacteria,2JJNM@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1171721_1	714943.Mucpa_7156	4.898e-128	427.0	COG1524@1|root,COG1524@2|Bacteria	2|Bacteria	S	mannose-ethanolamine phosphotransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
CMS1_k127_1171721_2	1123242.JH636434_gene4287	1.936e-126	431.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS1_k127_1171721_0	1121904.ARBP01000008_gene3234	1.513e-131	446.0	COG5492@1|root,COG5492@2|Bacteria,4NEAB@976|Bacteroidetes,47TBW@768503|Cytophagia	976|Bacteroidetes	N	Domain of unknown function (DUF5060)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF5060
CMS1_k127_1194064_0	886293.Sinac_1729	6.589e-133	433.0	COG0501@1|root,COG0501@2|Bacteria,2J0GY@203682|Planctomycetes	203682|Planctomycetes	O	CAAX prenyl protease N-terminal, five membrane helices	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,Peptidase_M48_N
CMS1_k127_1194064_1	1123242.JH636435_gene1120	3.029e-92	312.0	COG1506@1|root,COG1506@2|Bacteria,2J1ST@203682|Planctomycetes	203682|Planctomycetes	E	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
CMS1_k127_1194064_3	215803.DB30_2422	9.245e-13	81.0	COG0750@1|root,COG4932@1|root,COG0750@2|Bacteria,COG4932@2|Bacteria,1NXIX@1224|Proteobacteria,430KM@68525|delta/epsilon subdivisions,2WVSB@28221|Deltaproteobacteria,2YYGY@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS1_k127_1194064_2	926550.CLDAP_34870	9.769e-47	171.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	pdhA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K00162,ko:K11381	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
CMS1_k127_1200749_2	344747.PM8797T_24796	1.05e-63	230.0	COG1409@1|root,COG1409@2|Bacteria,2J1WA@203682|Planctomycetes	203682|Planctomycetes	S	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1200749_0	706587.Desti_1283	4.359e-135	463.0	COG1328@1|root,COG1328@2|Bacteria,1MWMS@1224|Proteobacteria,42M8V@68525|delta/epsilon subdivisions,2WJ7S@28221|Deltaproteobacteria,2MR3G@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Anaerobic ribonucleoside-triphosphate reductase	-	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	NRDD
CMS1_k127_1200749_3	1514668.JOOA01000002_gene3096	1.807e-19	104.0	COG1328@1|root,COG1328@2|Bacteria,1TR9K@1239|Firmicutes,247WF@186801|Clostridia,3WHPK@541000|Ruminococcaceae	186801|Clostridia	F	Ribonucleoside-triphosphate reductase	nrdD	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,NRDD
CMS1_k127_1200749_1	1051632.TPY_0308	3.825e-71	253.0	COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,248CR@186801|Clostridia,3WD01@538999|Clostridiales incertae sedis	186801|Clostridia	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
CMS1_k127_1204356_0	1173028.ANKO01000106_gene334	9.262e-162	516.0	COG0451@1|root,COG0451@2|Bacteria,1G0IT@1117|Cyanobacteria,1HA8Q@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM NAD dependent epimerase dehydratase family	-	-	5.1.3.10	ko:K12454	ko00520,map00520	-	R04266	RC00528	ko00000,ko00001,ko01000	-	-	-	Epimerase
CMS1_k127_1204356_1	926550.CLDAP_10440	1.319e-50	196.0	COG0438@1|root,COG0438@2|Bacteria,2G6KX@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4
CMS1_k127_120656_1	1123517.JOMR01000001_gene751	5.034e-142	459.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,1RMHP@1236|Gammaproteobacteria,45ZTK@72273|Thiotrichales	72273|Thiotrichales	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
CMS1_k127_120656_0	1125863.JAFN01000001_gene1869	5.534e-199	651.0	COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2WJ7V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Phenylalanyl-tRNA synthetase, beta subunit	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
CMS1_k127_120656_3	1125863.JAFN01000001_gene1870	1.428e-114	378.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,42MB0@68525|delta/epsilon subdivisions,2WJ42@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF987.Gmet_1415	Phe_tRNA-synt_N,tRNA-synt_2d
CMS1_k127_120656_7	1382306.JNIM01000001_gene3786	5.88e-56	203.0	COG0325@1|root,COG0325@2|Bacteria,2G6F1@200795|Chloroflexi	200795|Chloroflexi	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
CMS1_k127_120656_15	1303518.CCALI_00502	6.49e-13	82.0	COG0457@1|root,COG0457@2|Bacteria	1303518.CCALI_00502|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_120656_12	1047013.AQSP01000066_gene721	1.328e-20	102.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	pilI	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
CMS1_k127_120656_4	661478.OP10G_3703	8.046e-73	256.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	pilH	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_120656_16	582744.Msip34_2220	2.189e-07	63.0	COG3137@1|root,COG3137@2|Bacteria,1RHDT@1224|Proteobacteria,2VTTP@28216|Betaproteobacteria,2KKD2@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Protein of unknown function, DUF481	-	-	-	-	-	-	-	-	-	-	-	-	DUF481
CMS1_k127_120656_9	1342301.JASD01000008_gene2778	1.429e-38	160.0	COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,2TRD3@28211|Alphaproteobacteria,3ZWKJ@60136|Sulfitobacter	28211|Alphaproteobacteria	S	AI-2E family transporter	perM	-	-	ko:K03548	-	-	-	-	ko00000,ko02000	2.A.86.1	-	-	AI-2E_transport
CMS1_k127_120656_10	484770.UFO1_2361	1.742e-37	153.0	COG1183@1|root,COG1183@2|Bacteria,1TR44@1239|Firmicutes,4H442@909932|Negativicutes	909932|Negativicutes	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
CMS1_k127_120656_8	330214.NIDE1000	8.626e-47	176.0	COG0688@1|root,COG0688@2|Bacteria,3J0KD@40117|Nitrospirae	40117|Nitrospirae	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
CMS1_k127_120656_5	868595.Desca_0706	9.213e-69	241.0	COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,2498Z@186801|Clostridia,25ZZS@186807|Peptococcaceae	186801|Clostridia	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
CMS1_k127_120656_6	935567.JAES01000019_gene1044	3.003e-60	219.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,1RNGK@1236|Gammaproteobacteria,1X4AP@135614|Xanthomonadales	135614|Xanthomonadales	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
CMS1_k127_120656_2	1379281.AVAG01000042_gene829	1.264e-128	420.0	COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,42NA3@68525|delta/epsilon subdivisions,2WIQU@28221|Deltaproteobacteria,2M8U2@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
CMS1_k127_120656_11	903814.ELI_3491	1.314e-27	115.0	COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,24QNZ@186801|Clostridia,25X15@186806|Eubacteriaceae	186801|Clostridia	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
CMS1_k127_120656_14	228410.NE1591	1.043e-13	74.0	COG3668@1|root,COG3668@2|Bacteria,1N97P@1224|Proteobacteria,2WFXW@28216|Betaproteobacteria	28216|Betaproteobacteria	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
CMS1_k127_1211868_3	1429046.RR21198_0625	1.79e-80	274.0	COG0326@1|root,COG0326@2|Bacteria,2GNPQ@201174|Actinobacteria,4FV89@85025|Nocardiaceae	201174|Actinobacteria	O	Molecular chaperone. Has ATPase activity	htpG	GO:0000302,GO:0000303,GO:0000305,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0010035,GO:0016020,GO:0030312,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044464,GO:0050896,GO:0051716,GO:0070887,GO:0071450,GO:0071451,GO:0071944,GO:1901700,GO:1901701	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
CMS1_k127_1211868_4	518766.Rmar_1787	7.188e-77	268.0	COG0109@1|root,COG0109@2|Bacteria,4NF5A@976|Bacteroidetes,1FIYT@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
CMS1_k127_1211868_7	478741.JAFS01000002_gene875	9.135e-33	135.0	COG1999@1|root,COG1999@2|Bacteria,46VZB@74201|Verrucomicrobia,37GTT@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	SCO1/SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
CMS1_k127_1211868_6	1403819.BATR01000098_gene3260	1.445e-33	135.0	COG2322@1|root,COG2322@2|Bacteria,46SZT@74201|Verrucomicrobia,2IUT2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF420)	-	-	-	-	-	-	-	-	-	-	-	-	DUF420
CMS1_k127_1211868_0	1303518.CCALI_01474	2.63e-119	390.0	COG5285@1|root,COG5285@2|Bacteria	2|Bacteria	Q	dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
CMS1_k127_1211868_5	485914.Hmuk_0567	5.769e-55	201.0	COG5285@1|root,arCOG09157@2157|Archaea,2XTXQ@28890|Euryarchaeota,23V37@183963|Halobacteria	183963|Halobacteria	Q	COG5285 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
CMS1_k127_1211868_2	1123242.JH636434_gene5606	1.18e-97	331.0	COG0665@1|root,COG0665@2|Bacteria,2IXGH@203682|Planctomycetes	203682|Planctomycetes	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
CMS1_k127_1211868_1	945713.IALB_0296	2.463e-112	387.0	COG0475@1|root,COG0490@1|root,COG1226@1|root,COG0475@2|Bacteria,COG0490@2|Bacteria,COG1226@2|Bacteria	2|Bacteria	P	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)	kefB	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
CMS1_k127_1211868_8	580332.Slit_1887	2.651e-26	126.0	COG3669@1|root,COG3669@2|Bacteria	2|Bacteria	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,CBM_6,F5_F8_type_C,FIVAR,Glyco_hydro_106,Glyco_hydro_28,Melibiase_2
CMS1_k127_1223674_8	247490.KSU1_C1333	4.342e-15	87.0	COG4968@1|root,COG4968@2|Bacteria,2J519@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CMS1_k127_1223674_3	886293.Sinac_1691	5.801e-118	404.0	COG3379@1|root,COG3379@2|Bacteria,2IXA8@203682|Planctomycetes	203682|Planctomycetes	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
CMS1_k127_1223674_4	1303518.CCALI_01084	1.14e-67	256.0	COG3170@1|root,COG3170@2|Bacteria	2|Bacteria	NU	translation initiation factor activity	-	-	3.1.26.12	ko:K02945,ko:K08086,ko:K08300,ko:K08301,ko:K20276	ko02024,ko03010,ko03018,map02024,map03010,map03018	M00178,M00394	-	-	br01610,ko00000,ko00001,ko00002,ko01000,ko03009,ko03011,ko03019	-	-	-	RNase_E_G
CMS1_k127_1223674_6	1137799.GZ78_24210	3.437e-45	176.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,1RPR7@1236|Gammaproteobacteria,1XI4E@135619|Oceanospirillales	135619|Oceanospirillales	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
CMS1_k127_1223674_1	926550.CLDAP_17300	1.248e-153	491.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_1223674_7	671065.MetMK1DRAFT_00016260	4.689e-21	100.0	COG0666@1|root,arCOG04004@2157|Archaea,2XS0N@28889|Crenarchaeota	28889|Crenarchaeota	S	ankyrin repeats	-	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank_2,Ank_4
CMS1_k127_1223674_2	247490.KSU1_C1116	1.169e-123	413.0	COG0436@1|root,COG0436@2|Bacteria,2IX5E@203682|Planctomycetes	203682|Planctomycetes	E	PFAM Aminotransferase class I and II	-	-	2.6.1.1	ko:K00812,ko:K10907	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS1_k127_1223674_0	1142394.PSMK_07550	4.518e-156	508.0	COG2152@1|root,COG2152@2|Bacteria,2IYI2@203682|Planctomycetes	203682|Planctomycetes	G	beta-1,4-mannooligosaccharide phosphorylase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130
CMS1_k127_1223674_5	477974.Daud_0865	3.53e-56	201.0	COG0438@1|root,COG1331@1|root,COG0438@2|Bacteria,COG1331@2|Bacteria,1TQRQ@1239|Firmicutes,249H2@186801|Clostridia,2607T@186807|Peptococcaceae	186801|Clostridia	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS1_k127_1231056_7	1226325.HMPREF1548_00288	1.217e-08	68.0	COG1874@1|root,COG1874@2|Bacteria,1TSHK@1239|Firmicutes,249IJ@186801|Clostridia,36HK3@31979|Clostridiaceae	186801|Clostridia	G	beta-galactosidase Bga35B	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_35,Glyco_hydro_98M,NPCBM
CMS1_k127_1231056_4	1304880.JAGB01000001_gene276	2.198e-70	255.0	COG4198@1|root,COG4198@2|Bacteria,1TQSW@1239|Firmicutes,249E4@186801|Clostridia	186801|Clostridia	S	Conserved protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
CMS1_k127_1231056_3	436114.SYO3AOP1_1744	1.171e-83	300.0	COG2805@1|root,COG2805@2|Bacteria,2G3S2@200783|Aquificae	200783|Aquificae	NU	PFAM Type II secretion system protein E	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
CMS1_k127_1231056_2	1232410.KI421416_gene2592	1.469e-131	434.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,43UCF@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	response regulator	pilR	-	-	ko:K02667	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS1_k127_1231056_5	338966.Ppro_2511	3.239e-64	241.0	COG4191@1|root,COG4191@2|Bacteria,1QU7R@1224|Proteobacteria,43BS1@68525|delta/epsilon subdivisions,2X72V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM ATP-binding region, ATPase domain protein	-	-	2.7.13.3	ko:K02668	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA
CMS1_k127_1231056_1	1125863.JAFN01000001_gene2903	4.119e-132	430.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WIMF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	twitching motility protein	pilT-4	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
CMS1_k127_1231056_0	497964.CfE428DRAFT_0602	7.046e-178	574.0	COG2804@1|root,COG2804@2|Bacteria,46UFR@74201|Verrucomicrobia	2|Bacteria	NU	type II secretion system protein E	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
CMS1_k127_1231056_6	670487.Ocepr_0001	3.017e-56	206.0	COG0593@1|root,COG0593@2|Bacteria,1WIHX@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
CMS1_k127_1237424_4	161528.ED21_32124	3.319e-19	89.0	COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,2TQK0@28211|Alphaproteobacteria,2K2F6@204457|Sphingomonadales	204457|Sphingomonadales	L	COG2801 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve,rve_3
CMS1_k127_1237424_1	1297569.MESS2_1000038	1.65e-45	178.0	COG0500@1|root,COG2226@2|Bacteria,1NWX3@1224|Proteobacteria,2TURQ@28211|Alphaproteobacteria,43PQD@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Ubie_methyltran
CMS1_k127_1237424_0	1002340.AFCF01000029_gene3287	1.489e-101	339.0	COG0500@1|root,COG2226@2|Bacteria,1NWX3@1224|Proteobacteria,2TURQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
CMS1_k127_1237424_6	716928.AJQT01000119_gene4339	4.232e-07	51.0	COG3335@1|root,COG3335@2|Bacteria,1MW7X@1224|Proteobacteria,2TTH8@28211|Alphaproteobacteria,4BDG3@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	leucine-zipper of insertion element IS481	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_23,HTH_29,HTH_32
CMS1_k127_1237424_3	1238182.C882_2391	2.721e-19	91.0	2CFZY@1|root,33DC2@2|Bacteria,1NKRH@1224|Proteobacteria,2UKY5@28211|Alphaproteobacteria,2JY8B@204441|Rhodospirillales	204441|Rhodospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1237424_2	314231.FP2506_11297	3.915e-20	93.0	COG1525@1|root,COG1525@2|Bacteria,1PRMI@1224|Proteobacteria,2UA9S@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Staphylococcal nuclease homologue	-	-	-	-	-	-	-	-	-	-	-	-	SNase
CMS1_k127_1242754_0	1203611.KB894542_gene875	1.221e-116	391.0	COG3250@1|root,COG3250@2|Bacteria,4P1Y2@976|Bacteroidetes,2G2QU@200643|Bacteroidia	976|Bacteroidetes	G	alpha-L-rhamnosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106
CMS1_k127_1242754_1	497964.CfE428DRAFT_4016	7.931e-41	158.0	COG1595@1|root,COG1595@2|Bacteria,46UHS@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
CMS1_k127_1250672_1	330214.NIDE0535	2.092e-70	243.0	COG0530@1|root,COG0530@2|Bacteria,3J0V1@40117|Nitrospirae	40117|Nitrospirae	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
CMS1_k127_1250672_0	330214.NIDE0534	9.411e-139	452.0	COG1641@1|root,COG1641@2|Bacteria	2|Bacteria	H	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes	larC	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
CMS1_k127_1250672_3	330214.NIDE0532	2.856e-25	105.0	COG1691@1|root,COG1691@2|Bacteria	2|Bacteria	C	(AIR) carboxylase	cpmA	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
CMS1_k127_125503_1	886293.Sinac_7452	1.782e-08	66.0	COG3485@1|root,COG3485@2|Bacteria	2|Bacteria	Q	protocatechuate 3,4-dioxygenase activity	MA20_21340	-	1.16.3.3	ko:K03296,ko:K22349	-	-	-	-	ko00000,ko01000	2.A.6.2	-	-	CarboxypepD_reg,DUF11
CMS1_k127_125503_0	1123008.KB905692_gene40	6.823e-118	388.0	COG3669@1|root,COG3669@2|Bacteria	2|Bacteria	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,CBM_6,F5_F8_type_C,FIVAR,Glyco_hydro_106,Glyco_hydro_28,Melibiase_2
CMS1_k127_1255735_0	761193.Runsl_2801	3.203e-194	615.0	COG1409@1|root,COG1409@2|Bacteria,4NF9K@976|Bacteroidetes,47NVH@768503|Cytophagia	976|Bacteroidetes	S	N terminal of Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,MetallophosC,MetallophosN
CMS1_k127_1255735_1	1226325.HMPREF1548_01196	3.982e-43	163.0	28J61@1|root,2Z91S@2|Bacteria,1UYHJ@1239|Firmicutes,24EVG@186801|Clostridia,36HUS@31979|Clostridiaceae	2|Bacteria	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_129
CMS1_k127_1256173_0	1282362.AEAC466_19805	4.535e-74	261.0	COG1131@1|root,COG1131@2|Bacteria,1R3XF@1224|Proteobacteria	1224|Proteobacteria	V	abc transporter atp-binding protein	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_1256173_2	1282362.AEAC466_19800	1.288e-26	116.0	COG1725@1|root,COG1725@2|Bacteria,1NBUH@1224|Proteobacteria,2UM7T@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
CMS1_k127_1256173_3	631362.Thi970DRAFT_02720	4.082e-25	111.0	COG0517@1|root,COG0517@2|Bacteria,1PC6A@1224|Proteobacteria,1SX0M@1236|Gammaproteobacteria,1X1TW@135613|Chromatiales	135613|Chromatiales	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
CMS1_k127_1256173_1	207559.Dde_1324	3.213e-39	155.0	COG0363@1|root,COG0363@2|Bacteria,1R5K6@1224|Proteobacteria,42UV6@68525|delta/epsilon subdivisions,2WP1R@28221|Deltaproteobacteria,2MAEX@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	TIGRFAM 6-phosphogluconolactonase	pgl	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
CMS1_k127_1256173_4	616991.JPOO01000003_gene2364	5.071e-06	50.0	COG0584@1|root,COG0584@2|Bacteria,4NMGK@976|Bacteroidetes,1I6WB@117743|Flavobacteriia,23I23@178469|Arenibacter	976|Bacteroidetes	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
CMS1_k127_1262618_0	443143.GM18_2437	1.071e-05	58.0	COG4961@1|root,COG4961@2|Bacteria,1PUSH@1224|Proteobacteria,437D5@68525|delta/epsilon subdivisions,2XA18@28221|Deltaproteobacteria,43VQM@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	Tad
CMS1_k127_1270689_0	867845.KI911784_gene1400	9.737e-66	244.0	COG3119@1|root,COG3379@1|root,COG3119@2|Bacteria,COG3379@2|Bacteria,2G90N@200795|Chloroflexi	200795|Chloroflexi	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
CMS1_k127_127077_3	1303518.CCALI_00676	6.392e-24	104.0	COG3533@1|root,COG3533@2|Bacteria	2|Bacteria	S	Beta-L-arabinofuranosidase, GH127	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
CMS1_k127_127077_4	1156937.MFUM_1010003	1.864e-05	51.0	COG4864@1|root,COG4864@2|Bacteria,46TWZ@74201|Verrucomicrobia,37FZ0@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	SigmaW regulon antibacterial	-	-	-	-	-	-	-	-	-	-	-	-	YdfA_immunity
CMS1_k127_127077_2	1047013.AQSP01000108_gene2068	6.919e-30	121.0	COG0724@1|root,COG0724@2|Bacteria,2NPT0@2323|unclassified Bacteria	2|Bacteria	S	RNA recognition motif	rpbA	-	-	-	-	-	-	-	-	-	-	-	RRM_1
CMS1_k127_127077_0	469383.Cwoe_1837	5.563e-103	344.0	COG0761@1|root,COG0761@2|Bacteria,2GIZ7@201174|Actinobacteria,4CPHC@84995|Rubrobacteria	84995|Rubrobacteria	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
CMS1_k127_127077_1	204669.Acid345_1613	5.395e-46	167.0	COG0191@1|root,COG0191@2|Bacteria,3Y5I1@57723|Acidobacteria,2JJXG@204432|Acidobacteriia	204432|Acidobacteriia	G	Fructose-bisphosphate aldolase class-II	-	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
CMS1_k127_1274632_0	1002340.AFCF01000066_gene455	6.12e-129	428.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,34FCB@302485|Phaeobacter	28211|Alphaproteobacteria	T	Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
CMS1_k127_1274632_1	314278.NB231_15513	1.956e-88	295.0	COG1237@1|root,COG1237@2|Bacteria,1NK2I@1224|Proteobacteria	1224|Proteobacteria	S	Beta-lactamase domain protein	-	-	2.5.1.105	ko:K06897	ko00790,map00790	-	R10339	RC00121	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
CMS1_k127_127802_3	469381.Dpep_1211	0.0002972	50.0	COG1472@1|root,COG1472@2|Bacteria,3TBXC@508458|Synergistetes	508458|Synergistetes	G	Glycosyl hydrolase family 3 N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_3
CMS1_k127_127802_0	404380.Gbem_0212	2.608e-113	387.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,42M09@68525|delta/epsilon subdivisions,2WJ1G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
CMS1_k127_127802_2	504472.Slin_3405	2.164e-82	300.0	COG2133@1|root,COG2133@2|Bacteria,4NJ2B@976|Bacteroidetes,47PRK@768503|Cytophagia	976|Bacteroidetes	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_127802_1	1267534.KB906760_gene1240	9.27e-105	343.0	COG3408@1|root,COG3408@2|Bacteria,3Y47W@57723|Acidobacteria,2JKGP@204432|Acidobacteriia	204432|Acidobacteriia	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1293665_1	1101195.Meth11DRAFT_2009	1.288e-49	182.0	COG3832@1|root,COG3832@2|Bacteria,1N3GA@1224|Proteobacteria,2WFY7@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
CMS1_k127_1293665_0	247634.GPB2148_1961	3.9e-158	516.0	COG1524@1|root,COG1524@2|Bacteria,1R5V5@1224|Proteobacteria,1S06C@1236|Gammaproteobacteria,1J9AQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	proteins of the AP superfamily	pafA	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
CMS1_k127_1296916_2	234267.Acid_2426	2.879e-54	199.0	COG5588@1|root,COG5588@2|Bacteria,3Y7RN@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF1326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1326
CMS1_k127_1296916_3	886293.Sinac_6838	3.315e-09	61.0	296HQ@1|root,2ZTT7@2|Bacteria,2J4NZ@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1296916_0	234267.Acid_2421	7.095e-91	309.0	COG1319@1|root,COG1319@2|Bacteria,3Y3NU@57723|Acidobacteria	57723|Acidobacteria	C	PFAM molybdopterin dehydrogenase, FAD-binding	-	-	1.17.1.4	ko:K11178	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
CMS1_k127_1296916_1	204669.Acid345_0762	9.996e-61	211.0	COG1529@1|root,COG1529@2|Bacteria,3Y2ME@57723|Acidobacteria,2JIZI@204432|Acidobacteriia	204432|Acidobacteriia	C	aldehyde oxidase and xanthine dehydrogenase a b hammerhead	-	-	1.17.1.4	ko:K11177	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
CMS1_k127_1305036_3	102129.Lepto7375DRAFT_3962	4.061e-66	234.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
CMS1_k127_1305036_10	2850.Phatr22554	9.062e-22	109.0	COG0438@1|root,KOG0853@2759|Eukaryota,2XC0I@2836|Bacillariophyta	2836|Bacillariophyta	M	Glycosyl transferases group 1	-	-	2.4.1.132,2.4.1.257	ko:K03843	ko00510,ko00513,ko01100,map00510,map00513,map01100	M00055	R05973,R06238	-	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT4	-	Glycos_transf_1
CMS1_k127_1305036_11	558169.AGAV01000003_gene2834	1.8e-20	106.0	2DJP7@1|root,306TY@2|Bacteria,1VSQ7@1239|Firmicutes,4HU17@91061|Bacilli	91061|Bacilli	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1
CMS1_k127_1305036_9	1122939.ATUD01000006_gene1712	2.017e-25	122.0	COG2227@1|root,COG2227@2|Bacteria,2GU8A@201174|Actinobacteria	201174|Actinobacteria	H	Protein of unknown function (DUF1698)	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1305036_2	864702.OsccyDRAFT_3648	3.41e-72	267.0	COG2242@1|root,COG4076@1|root,COG2242@2|Bacteria,COG4076@2|Bacteria,1G543@1117|Cyanobacteria,1HD58@1150|Oscillatoriales	1117|Cyanobacteria	H	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
CMS1_k127_1305036_5	404380.Gbem_3720	1.143e-48	201.0	COG1216@1|root,COG4627@1|root,COG1216@2|Bacteria,COG4627@2|Bacteria,1RGUZ@1224|Proteobacteria,42SZI@68525|delta/epsilon subdivisions,2X7XM@28221|Deltaproteobacteria	68525|delta/epsilon subdivisions	H	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_11
CMS1_k127_1305036_7	1286631.X805_32760	4.736e-35	156.0	COG0438@1|root,COG0438@2|Bacteria,1MVIM@1224|Proteobacteria,2VJT7@28216|Betaproteobacteria,1KMBZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Glycosyl transferases group 1	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
CMS1_k127_1305036_4	358681.BBR47_17410	4.698e-58	214.0	COG1215@1|root,COG1215@2|Bacteria,1V7FY@1239|Firmicutes,4HQQ4@91061|Bacilli,274AA@186822|Paenibacillaceae	91061|Bacilli	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS1_k127_1305036_6	1158318.ATXC01000001_gene245	4.564e-47	183.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	2.4.1.83	ko:K00721,ko:K07011,ko:K20444	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2
CMS1_k127_1305036_0	357808.RoseRS_0010	3.396e-115	403.0	COG0823@1|root,COG0823@2|Bacteria,2G8T5@200795|Chloroflexi,376FH@32061|Chloroflexia	32061|Chloroflexia	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
CMS1_k127_1305036_12	1122179.KB890425_gene3326	6.236e-06	60.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_5,Calx-beta
CMS1_k127_1305036_13	246197.MXAN_1580	4.302e-05	57.0	COG3568@1|root,COG3568@2|Bacteria,1N2ZJ@1224|Proteobacteria,42WUR@68525|delta/epsilon subdivisions,2WSUA@28221|Deltaproteobacteria,2YUA6@29|Myxococcales	28221|Deltaproteobacteria	PQ	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos,LTD
CMS1_k127_1305036_8	118168.MC7420_7195	2.675e-26	119.0	COG4424@1|root,COG4424@2|Bacteria	2|Bacteria	S	carbohydrate metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1,Sulfotransfer_3
CMS1_k127_1305036_1	272123.Anacy_0442	3.735e-102	349.0	COG0665@1|root,COG3349@1|root,COG0665@2|Bacteria,COG3349@2|Bacteria	2|Bacteria	CH	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'	-	-	1.3.5.5	ko:K02293	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00097	R04786,R04787,R07510,R09652,R09653,R09654	RC01214,RC01958,RC03092,RC03093	ko00000,ko00001,ko00002,ko01000	-	-	-	ADC,Amino_oxidase,NAD_binding_8
CMS1_k127_1310088_2	1464048.JNZS01000012_gene3336	4.024e-05	51.0	COG3345@1|root,COG4409@1|root,COG3345@2|Bacteria,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	rafA	-	3.2.1.22,3.2.1.52	ko:K07407,ko:K12373	ko00052,ko00511,ko00513,ko00520,ko00531,ko00561,ko00600,ko00603,ko00604,ko01100,ko04142,map00052,map00511,map00513,map00520,map00531,map00561,map00600,map00603,map00604,map01100,map04142	M00079	R00022,R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06004,R06091,R11316	RC00049,RC00059,RC00451	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	BNR_2,F5_F8_type_C,Glyco_hydro_36C,Glyco_hydro_36N,Melibiase
CMS1_k127_1310088_0	641524.ADICYQ_1533	1.676e-102	346.0	COG4409@1|root,COG4409@2|Bacteria,4NKWU@976|Bacteroidetes	976|Bacteroidetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
CMS1_k127_1310088_1	485917.Phep_3584	8.496e-65	239.0	COG4409@1|root,COG4409@2|Bacteria,4NT25@976|Bacteroidetes	976|Bacteroidetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
CMS1_k127_1318139_0	1445613.JALM01000074_gene6652	3.069e-164	529.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria,4EARD@85010|Pseudonocardiales	201174|Actinobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CMS1_k127_1318998_2	886293.Sinac_2763	6.219e-74	254.0	COG2382@1|root,COG2382@2|Bacteria,2IYMZ@203682|Planctomycetes	203682|Planctomycetes	P	Putative esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase
CMS1_k127_1318998_0	240015.ACP_1143	1.534e-250	794.0	COG3534@1|root,COG3534@2|Bacteria,3Y2MY@57723|Acidobacteria,2JKIM@204432|Acidobacteriia	204432|Acidobacteriia	G	alpha-L-arabinofuranosidase	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	-
CMS1_k127_1318998_1	382464.ABSI01000011_gene2425	1.569e-89	300.0	COG2382@1|root,COG2382@2|Bacteria,46YZE@74201|Verrucomicrobia,2IU0Q@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
CMS1_k127_1324367_2	196162.Noca_2097	1.43e-26	111.0	COG2303@1|root,COG2303@2|Bacteria,2I5YA@201174|Actinobacteria,4DR7N@85009|Propionibacteriales	201174|Actinobacteria	E	GMC oxidoreductase	choD_2	-	1.1.1.400	ko:K20927	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N,Gluconate_2-dh3
CMS1_k127_1324367_0	436308.Nmar_1135	4.424e-58	223.0	COG0421@1|root,arCOG00050@2157|Archaea	2157|Archaea	H	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synt_N,Spermine_synth
CMS1_k127_1324367_1	1156937.MFUM_190022	8.238e-32	128.0	COG0520@1|root,COG0520@2|Bacteria,46SC0@74201|Verrucomicrobia,37G89@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
CMS1_k127_1329843_5	313628.LNTAR_06729	2.989e-22	101.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS1_k127_1329843_0	357808.RoseRS_3616	3.749e-161	529.0	COG3525@1|root,COG3525@2|Bacteria,2G609@200795|Chloroflexi,376QW@32061|Chloroflexia	32061|Chloroflexia	G	Glycoside hydrolase, family 20	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_20,Glyco_hydro_20b
CMS1_k127_1329843_4	583355.Caka_2087	1.009e-25	109.0	COG3785@1|root,COG3785@2|Bacteria	2|Bacteria	S	Hemimethylated DNA-binding protein YccV like	hspQ	-	-	ko:K11940	-	-	-	-	ko00000,ko03036	-	-	-	YccV-like
CMS1_k127_1329843_2	472759.Nhal_0020	1.611e-71	246.0	COG0693@1|root,COG0693@2|Bacteria,1N7T2@1224|Proteobacteria,1RSBI@1236|Gammaproteobacteria,1WY2E@135613|Chromatiales	135613|Chromatiales	S	TIGRFAM DJ-1 family protein	-	-	3.5.1.124	ko:K03152	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
CMS1_k127_1329843_3	1499967.BAYZ01000057_gene4726	6.724e-67	237.0	COG1082@1|root,COG1082@2|Bacteria,2NRTI@2323|unclassified Bacteria	2|Bacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS1_k127_1329843_1	1122917.KB899666_gene3405	4.072e-95	327.0	COG0412@1|root,COG0412@2|Bacteria,1TQQS@1239|Firmicutes,4HGK4@91061|Bacilli,26SWC@186822|Paenibacillaceae	1239|Firmicutes	Q	Abhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_7,BAAT_C
CMS1_k127_1330239_0	1434325.AZQN01000008_gene2951	1.607e-149	489.0	COG1409@1|root,COG1409@2|Bacteria,4NIGR@976|Bacteroidetes,47P2I@768503|Cytophagia	976|Bacteroidetes	S	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
CMS1_k127_1330239_1	313628.LNTAR_07269	2.447e-27	117.0	COG3119@1|root,COG3119@2|Bacteria	313628.LNTAR_07269|-	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1335938_0	161156.JQKW01000006_gene1387	4.099e-11	74.0	COG4974@1|root,COG4974@2|Bacteria,2GI3R@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
CMS1_k127_1341036_6	886293.Sinac_1097	1.326e-19	104.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,2IXM2@203682|Planctomycetes	203682|Planctomycetes	C	heme-binding domain, Pirellula Verrucomicrobium type	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,HEAT_2
CMS1_k127_1341036_3	1267535.KB906767_gene361	1.279e-84	300.0	COG0673@1|root,COG0673@2|Bacteria,3Y6Q3@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_1341036_5	497964.CfE428DRAFT_5116	3.154e-24	106.0	2942H@1|root,2ZRH9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1341036_9	1075090.GOAMR_04_01030	7.334e-10	72.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	ko:K13687	-	-	-	-	ko00000,ko01000,ko01003	-	GT89	-	PMT_2
CMS1_k127_1341036_4	1121939.L861_13660	4.885e-74	270.0	COG1520@1|root,COG1520@2|Bacteria,1NYGT@1224|Proteobacteria,1T1IK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotran_2,Arylsulfotrans
CMS1_k127_1341036_1	886293.Sinac_0098	1.313e-186	611.0	COG3518@1|root,COG3518@2|Bacteria,2IYH2@203682|Planctomycetes	203682|Planctomycetes	S	anti-sigma factor antagonist activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1341036_10	136037.KDR09886	1.469e-08	62.0	COG0666@1|root,KOG4214@2759|Eukaryota,3A0YG@33154|Opisthokonta,3BT29@33208|Metazoa,3D97I@33213|Bilateria,41ZTB@6656|Arthropoda,3SN2N@50557|Insecta	33208|Metazoa	K	Ankyrin repeats (many copies)	-	GO:0001558,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0008150,GO:0030307,GO:0040008,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043565,GO:0044424,GO:0044444,GO:0044464,GO:0045927,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0065007,GO:0097159,GO:1901363	-	-	-	-	-	-	-	-	-	-	Ank,Ank_2,Ank_4
CMS1_k127_1341036_7	247490.KSU1_C1333	8.995e-16	89.0	COG4968@1|root,COG4968@2|Bacteria,2J519@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CMS1_k127_1341036_11	209285.XP_006691417.1	5.583e-08	59.0	COG0666@1|root,KOG4412@2759|Eukaryota,39VDP@33154|Opisthokonta,3NXYE@4751|Fungi,3QQ59@4890|Ascomycota,2173W@147550|Sordariomycetes,3UFAE@5139|Sordariales,3HG94@35718|Chaetomiaceae	4751|Fungi	O	Ankyrin repeat	NAS6	GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0019538,GO:0022607,GO:0032991,GO:0034622,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043248,GO:0043933,GO:0044085,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070682,GO:0071704,GO:0071840,GO:1901564	-	ko:K06694	-	-	-	-	ko00000,ko03051	-	-	-	Ank_2,Ank_3,Ank_4,Ank_5
CMS1_k127_1341036_8	247490.KSU1_C1333	1.225e-15	89.0	COG4968@1|root,COG4968@2|Bacteria,2J519@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CMS1_k127_1341036_0	706587.Desti_3602	2.139e-240	752.0	COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,42Y69@68525|delta/epsilon subdivisions,2WJ5F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KT	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
CMS1_k127_1341036_2	665571.STHERM_c13210	3.315e-85	294.0	COG3604@1|root,COG3604@2|Bacteria,2J5TK@203691|Spirochaetes	203691|Spirochaetes	KT	Fis Family	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
CMS1_k127_1347054_5	742738.HMPREF9460_02951	2.14e-57	215.0	COG1454@1|root,COG1454@2|Bacteria,1UY3E@1239|Firmicutes,25E9A@186801|Clostridia	186801|Clostridia	C	alcohol dehydrogenase	-	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
CMS1_k127_1347054_4	243090.RB7706	1.476e-57	222.0	COG0475@1|root,COG1762@1|root,COG0475@2|Bacteria,COG1762@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	kefB	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770,ko:K02806	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	Na_H_Exchanger,PTS_EIIA_2
CMS1_k127_1347054_6	886293.Sinac_6923	2.711e-49	185.0	COG2159@1|root,COG2159@2|Bacteria,2IZCY@203682|Planctomycetes	203682|Planctomycetes	S	metal-dependent hydrolase of the TIM-barrel fold	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
CMS1_k127_1347054_8	886293.Sinac_0669	2.16e-35	145.0	COG2159@1|root,COG2159@2|Bacteria,2IZB9@203682|Planctomycetes	2|Bacteria	S	metal-dependent hydrolase of the TIM-barrel fold	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
CMS1_k127_1347054_3	247490.KSU1_B0081	1.91e-116	388.0	COG1208@1|root,COG1208@2|Bacteria,2J0MF@203682|Planctomycetes	203682|Planctomycetes	JM	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,NTP_transferase
CMS1_k127_1347054_1	1340493.JNIF01000003_gene1887	1.657e-137	450.0	COG0673@1|root,COG0673@2|Bacteria,3Y6C9@57723|Acidobacteria	57723|Acidobacteria	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_1347054_0	521674.Plim_3456	1.343e-154	532.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS1_k127_1347054_7	1242864.D187_006888	1.015e-48	181.0	COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,42SP5@68525|delta/epsilon subdivisions,2WP39@28221|Deltaproteobacteria,2YUQU@29|Myxococcales	28221|Deltaproteobacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
CMS1_k127_1347054_2	926569.ANT_06990	1.003e-134	440.0	COG2317@1|root,COG2317@2|Bacteria,2G7UQ@200795|Chloroflexi	200795|Chloroflexi	E	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues	-	-	3.4.17.19	ko:K01299	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M32
CMS1_k127_1349542_1	497964.CfE428DRAFT_4366	1.323e-24	104.0	COG1520@1|root,COG1520@2|Bacteria,46TRS@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CMS1_k127_1349542_0	1174528.JH992893_gene5856	0.0	1192.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria	1117|Cyanobacteria	Q	Amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,PilZ,Thioesterase
CMS1_k127_1349542_2	1151126.AQYI01000005_gene2354	2.593e-06	55.0	28Z5Z@1|root,2ZKY9@2|Bacteria,2H8K9@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1349542_3	180281.CPCC7001_1792	1.275e-05	47.0	COG4974@1|root,COG4974@2|Bacteria,1G224@1117|Cyanobacteria,22TC6@167375|Cyanobium	1117|Cyanobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
CMS1_k127_1357544_2	471854.Dfer_3997	2.421e-89	310.0	COG3394@1|root,COG3394@2|Bacteria,4NFY5@976|Bacteroidetes,47MN2@768503|Cytophagia	976|Bacteroidetes	G	YdjC-like protein	-	-	3.5.1.105	ko:K03478	-	-	-	-	ko00000,ko01000	-	-	-	YdjC
CMS1_k127_1357544_3	1434325.AZQN01000005_gene3626	1.481e-84	294.0	COG3394@1|root,COG3394@2|Bacteria,4NFY5@976|Bacteroidetes,47MN2@768503|Cytophagia	976|Bacteroidetes	G	YdjC-like protein	-	-	3.5.1.105	ko:K03478	-	-	-	-	ko00000,ko01000	-	-	-	YdjC
CMS1_k127_1357544_6	641524.ADICYQ_4337	2.7e-21	109.0	COG3356@1|root,COG3356@2|Bacteria,4NJPV@976|Bacteroidetes,47JM2@768503|Cytophagia	976|Bacteroidetes	S	Neutral/alkaline non-lysosomal ceramidase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
CMS1_k127_1357544_1	1444712.BN1013_02040	9.859e-101	345.0	COG3356@1|root,COG3356@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
CMS1_k127_1357544_4	1303518.CCALI_01799	1.487e-49	189.0	COG5285@1|root,COG5285@2|Bacteria	2|Bacteria	Q	dioxygenase activity	-	-	-	ko:K18565	ko00332,ko01130,map00332,map01130	-	R10740,R10741,R10742	RC03267,RC03268,RC03269	ko00000,ko00001,ko01000	-	-	-	PhyH
CMS1_k127_1357544_5	1122927.KB895414_gene4824	2.276e-43	162.0	COG3254@1|root,COG3254@2|Bacteria,1V1XT@1239|Firmicutes	1239|Firmicutes	S	L-rhamnose mutarotase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2,rhaM
CMS1_k127_1357544_0	1492737.FEM08_10420	2.539e-174	563.0	COG4146@1|root,COG4146@2|Bacteria,4NE9S@976|Bacteroidetes,1IJTV@117743|Flavobacteriia,2NVD2@237|Flavobacterium	976|Bacteroidetes	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
CMS1_k127_1357544_7	1121859.KB890756_gene1447	7.29e-17	93.0	COG3408@1|root,COG3408@2|Bacteria,4NE1I@976|Bacteroidetes	976|Bacteroidetes	G	glycogen debranching	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H,DUF4450,DUF608
CMS1_k127_1373376_0	706587.Desti_1422	7.995e-320	998.0	COG0046@1|root,COG1828@1|root,COG0046@2|Bacteria,COG1828@2|Bacteria,1MYN4@1224|Proteobacteria,42M08@68525|delta/epsilon subdivisions,2WITS@28221|Deltaproteobacteria,2MR4G@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,PurS
CMS1_k127_1373376_3	313628.LNTAR_04641	7.144e-92	310.0	COG0047@1|root,COG0047@2|Bacteria	2|Bacteria	F	phosphoribosylformylglycinamidine synthase activity	purL	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016884,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	iECH74115_1262.ECH74115_3792,iECO111_1330.ECO111_3283,iECSP_1301.ECSP_3501,iECs_1301.ECs3423,iG2583_1286.G2583_3088,iJN746.PP_1037,ic_1306.c3080	AIRS_C,GATase_5
CMS1_k127_1373376_1	1123242.JH636435_gene1524	1.033e-127	427.0	COG2936@1|root,COG2936@2|Bacteria,2J2G5@203682|Planctomycetes	203682|Planctomycetes	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
CMS1_k127_1373376_6	1283300.ATXB01000001_gene1311	6.638e-05	55.0	COG0457@1|root,COG0457@2|Bacteria,1MXMD@1224|Proteobacteria,1RSI5@1236|Gammaproteobacteria,1XGD7@135618|Methylococcales	135618|Methylococcales	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19
CMS1_k127_1373376_5	1123278.KB893580_gene897	2.142e-12	68.0	COG2010@1|root,COG2010@2|Bacteria,4NN0I@976|Bacteroidetes,47PFQ@768503|Cytophagia	976|Bacteroidetes	C	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CMS1_k127_1373376_4	1123508.JH636441_gene3102	3.215e-60	218.0	COG4099@1|root,COG4099@2|Bacteria,2IZGJ@203682|Planctomycetes	203682|Planctomycetes	M	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2,DLH,Peptidase_S9
CMS1_k127_1373376_2	314230.DSM3645_24180	1.106e-116	394.0	COG4692@1|root,COG4692@2|Bacteria,2IX4M@203682|Planctomycetes	203682|Planctomycetes	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2,VCBS
CMS1_k127_1378124_3	622637.KE124774_gene3248	3.091e-28	117.0	COG3385@1|root,COG3385@2|Bacteria,1QURV@1224|Proteobacteria,2TW56@28211|Alphaproteobacteria,371IT@31993|Methylocystaceae	28211|Alphaproteobacteria	L	Transposase DDE domain group 1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
CMS1_k127_1378124_5	994573.T472_0209625	8.356e-05	55.0	COG1470@1|root,COG1470@2|Bacteria	2|Bacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	Gram_pos_anchor,Peptidase_M73
CMS1_k127_1378124_2	530564.Psta_1246	6.863e-48	191.0	COG3391@1|root,COG3391@2|Bacteria,2J1IA@203682|Planctomycetes	203682|Planctomycetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1378124_1	1265313.HRUBRA_02724	4.062e-104	356.0	COG1914@1|root,COG1914@2|Bacteria	2|Bacteria	P	metal ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
CMS1_k127_1378124_0	450851.PHZ_c2448	1.37e-124	415.0	COG1331@1|root,COG1331@2|Bacteria,1R570@1224|Proteobacteria,2TUBQ@28211|Alphaproteobacteria,2KFKA@204458|Caulobacterales	204458|Caulobacterales	O	Pectic acid lyase	-	-	-	-	-	-	-	-	-	-	-	-	Pec_lyase
CMS1_k127_1382807_0	483219.LILAB_16500	2.243e-43	175.0	COG1305@1|root,COG1305@2|Bacteria,1RARF@1224|Proteobacteria,42R14@68525|delta/epsilon subdivisions,2WN3R@28221|Deltaproteobacteria,2YWMC@29|Myxococcales	28221|Deltaproteobacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
CMS1_k127_1393268_1	526227.Mesil_0054	1.225e-19	94.0	COG0730@1|root,COG0730@2|Bacteria	2|Bacteria	S	response to heat	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
CMS1_k127_142618_4	1324957.K933_01477	8.782e-15	74.0	COG0673@1|root,arCOG01622@2157|Archaea,2XVGS@28890|Euryarchaeota,23UPE@183963|Halobacteria	183963|Halobacteria	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_142618_0	357808.RoseRS_3453	6.193e-98	323.0	COG3828@1|root,COG3828@2|Bacteria,2G61G@200795|Chloroflexi	200795|Chloroflexi	S	Trehalose utilisation	-	-	-	ko:K09992	-	-	-	-	ko00000	-	-	-	ThuA
CMS1_k127_142618_2	330084.JNYZ01000003_gene2151	7.396e-37	146.0	COG3963@1|root,COG3963@2|Bacteria,2I93P@201174|Actinobacteria,4E3Y8@85010|Pseudonocardiales	201174|Actinobacteria	I	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS1_k127_142618_1	1122138.AQUZ01000054_gene5919	2.971e-82	282.0	COG0395@1|root,COG0395@2|Bacteria,2GMTH@201174|Actinobacteria	201174|Actinobacteria	G	ABC transporter (Permease)	-	-	-	ko:K05815	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.3	-	-	BPD_transp_1
CMS1_k127_142618_3	525904.Tter_2292	5.648e-15	77.0	COG1175@1|root,COG1175@2|Bacteria	2|Bacteria	P	transmembrane transport	ugpA	-	-	ko:K02025,ko:K05814,ko:K10118,ko:K10237,ko:K10241,ko:K15771,ko:K17235,ko:K17316	ko02010,map02010	M00196,M00198,M00204,M00206,M00207,M00491,M00602,M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.17,3.A.1.1.2,3.A.1.1.23,3.A.1.1.24,3.A.1.1.28,3.A.1.1.3,3.A.1.1.30,3.A.1.1.34	-	-	BPD_transp_1
CMS1_k127_1429168_0	349124.Hhal_1975	3.724e-161	516.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RP7E@1236|Gammaproteobacteria,1WWC9@135613|Chromatiales	135613|Chromatiales	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	-	-	3.5.1.4,6.3.5.6,6.3.5.7	ko:K01426,ko:K02433	ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120	-	R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
CMS1_k127_1429168_1	187272.Mlg_0876	6.16e-117	385.0	COG0111@1|root,COG0111@2|Bacteria,1MW1U@1224|Proteobacteria,1RNYC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
CMS1_k127_1434722_1	1449069.JMLO01000013_gene1292	8.337e-35	148.0	COG0638@1|root,COG0638@2|Bacteria,2GMC6@201174|Actinobacteria,4FUSS@85025|Nocardiaceae	201174|Actinobacteria	O	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine	pafA	GO:0000166,GO:0000302,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0016020,GO:0016740,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0030312,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034599,GO:0034614,GO:0035639,GO:0035690,GO:0036094,GO:0036211,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044464,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070490,GO:0070647,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097159,GO:0097366,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170	6.3.1.19	ko:K13571	-	M00342	R11207	RC00090,RC00096	ko00000,ko00002,ko01000,ko03051	-	-	-	Pup_ligase
CMS1_k127_1434722_0	1137268.AZXF01000011_gene3749	6.675e-54	208.0	COG4122@1|root,COG4122@2|Bacteria,2GJGI@201174|Actinobacteria,4EGNP@85012|Streptosporangiales	201174|Actinobacteria	S	Pup-ligase protein	dop	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006464,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0016810,GO:0016811,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070490,GO:0070647,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	3.5.1.119	ko:K20814	-	-	-	-	ko00000,ko01000,ko03051	-	-	-	Pup_ligase
CMS1_k127_1434722_2	1392502.JNIO01000002_gene707	0.0001084	54.0	2CC4J@1|root,2Z7W8@2|Bacteria,1UX5W@1239|Firmicutes,4H2HV@909932|Negativicutes	909932|Negativicutes	S	Domain of unknown function (DUF932)	-	-	-	-	-	-	-	-	-	-	-	-	DUF932
CMS1_k127_1436390_1	883.DvMF_0192	6.226e-38	144.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,42MD4@68525|delta/epsilon subdivisions,2WJ7Z@28221|Deltaproteobacteria,2MAKH@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	ATP-dependent helicase HrpB	hrpB	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
CMS1_k127_1436390_2	1235457.C404_03565	5.565e-23	107.0	28WUQ@1|root,2ZIU4@2|Bacteria,1P7TM@1224|Proteobacteria,2W7CR@28216|Betaproteobacteria,1KEBR@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1436390_0	1089550.ATTH01000001_gene162	1.29e-154	501.0	COG0364@1|root,COG0364@2|Bacteria,4NE59@976|Bacteroidetes,1FIS5@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
CMS1_k127_1438458_7	555500.I215_15275	1.498e-05	54.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,4NE4W@976|Bacteroidetes,1HX2D@117743|Flavobacteriia	976|Bacteroidetes	K	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_21,TPR_6,TPR_8
CMS1_k127_1438458_2	641524.ADICYQ_2988	5.379e-58	220.0	COG0673@1|root,COG0673@2|Bacteria,4NFFJ@976|Bacteroidetes,47MIT@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_1438458_1	794903.OPIT5_07380	4.001e-68	244.0	COG0670@1|root,COG0670@2|Bacteria,46VEY@74201|Verrucomicrobia,3K9GN@414999|Opitutae	414999|Opitutae	S	Belongs to the BI1 family	-	-	-	ko:K06890	-	-	-	-	ko00000	-	-	-	Bax1-I
CMS1_k127_1438458_3	926560.KE387023_gene2058	2.374e-41	162.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
CMS1_k127_1438458_6	1408473.JHXO01000003_gene2584	8.952e-08	63.0	2E676@1|root,330VQ@2|Bacteria,4PA7N@976|Bacteroidetes,2FZJU@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1438458_0	338969.Rfer_4129	9.386e-86	288.0	COG1573@1|root,COG1573@2|Bacteria,1R9XV@1224|Proteobacteria,2VQ52@28216|Betaproteobacteria,4ADVB@80864|Comamonadaceae	28216|Betaproteobacteria	L	Uracil DNA glycosylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DUF488,UDG
CMS1_k127_1438458_4	1340493.JNIF01000004_gene767	7.51e-39	158.0	COG0662@1|root,COG0662@2|Bacteria,3Y4MC@57723|Acidobacteria	57723|Acidobacteria	G	PFAM Cupin 2, conserved barrel	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS1_k127_1438458_5	502025.Hoch_6598	1.08e-08	56.0	COG0493@1|root,COG0493@2|Bacteria,1P58U@1224|Proteobacteria,4392A@68525|delta/epsilon subdivisions,2X47Z@28221|Deltaproteobacteria,2YYG2@29|Myxococcales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	Pyr_redox_2
CMS1_k127_144234_7	452637.Oter_3514	2.091e-08	59.0	2F286@1|root,33V6C@2|Bacteria,46V8R@74201|Verrucomicrobia,3K9H5@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_144234_3	452637.Oter_3514	1.181e-53	197.0	2F286@1|root,33V6C@2|Bacteria,46V8R@74201|Verrucomicrobia,3K9H5@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_144234_8	706587.Desti_5102	0.0003226	51.0	COG5660@1|root,COG5660@2|Bacteria	2|Bacteria	S	Putative zinc-finger	sigC	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	zf-HC2
CMS1_k127_144234_6	1267533.KB906738_gene2213	1.104e-18	94.0	COG1595@1|root,COG1595@2|Bacteria,3Y3BS@57723|Acidobacteria,2JIDF@204432|Acidobacteriia	204432|Acidobacteriia	K	RNA polymerase sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_144234_0	1121403.AUCV01000003_gene1787	1.237e-148	494.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,1MV4K@1224|Proteobacteria,42N93@68525|delta/epsilon subdivisions,2WJ9N@28221|Deltaproteobacteria,2MHX8@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,TrkA_C,Voltage_CLC
CMS1_k127_144234_2	667014.Thein_0946	3.07e-78	269.0	COG1235@1|root,COG1235@2|Bacteria,2GHT4@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
CMS1_k127_144234_4	1121904.ARBP01000033_gene3213	2.178e-34	145.0	28K60@1|root,2Z9UH@2|Bacteria,4NHE6@976|Bacteroidetes,47UNS@768503|Cytophagia	976|Bacteroidetes	S	Methane oxygenase PmoA	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
CMS1_k127_144234_1	649638.Trad_1837	4.954e-97	332.0	COG4948@1|root,COG4948@2|Bacteria,1WMNA@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	Mandelate racemase muconate lactonizing enzyme	ykfB	-	5.1.1.20	ko:K19802	-	-	R10938	RC03309	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
CMS1_k127_144234_5	247490.KSU1_C1333	3.411e-20	102.0	COG4968@1|root,COG4968@2|Bacteria,2J519@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CMS1_k127_145114_4	697281.Mahau_0771	4.097e-20	91.0	COG0395@1|root,COG0395@2|Bacteria,1TSAB@1239|Firmicutes,25C5T@186801|Clostridia,42JEU@68295|Thermoanaerobacterales	186801|Clostridia	P	COGs COG0395 ABC-type sugar transport system permease component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_145114_2	278963.ATWD01000001_gene3347	6.744e-71	265.0	COG5434@1|root,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBM-like,F5_F8_type_C,Pectate_lyase_3
CMS1_k127_145114_3	313595.P700755_003529	1.204e-36	147.0	28JH1@1|root,2Z9AM@2|Bacteria,4NJYJ@976|Bacteroidetes,1I0ZC@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_145114_0	1536769.P40081_18990	8.494e-275	866.0	COG3537@1|root,COG3537@2|Bacteria,1TQAG@1239|Firmicutes,4HBMP@91061|Bacilli,26UBX@186822|Paenibacillaceae	91061|Bacilli	G	Glycosyl hydrolase family 92	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_92
CMS1_k127_145114_1	1214101.BN159_0193	9.251e-113	376.0	COG4030@1|root,COG4030@2|Bacteria,2GJFD@201174|Actinobacteria	201174|Actinobacteria	M	Protein of unknown function (DUF2961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
CMS1_k127_146098_5	675812.VHA_000057	3.774e-38	152.0	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,1S247@1236|Gammaproteobacteria,1XSD0@135623|Vibrionales	135623|Vibrionales	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008463,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
CMS1_k127_146098_4	1121428.DESHY_40090___1	1.758e-64	226.0	COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,2487H@186801|Clostridia,2612W@186807|Peptococcaceae	186801|Clostridia	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
CMS1_k127_146098_3	1122223.KB890688_gene1648	4.115e-80	276.0	COG0288@1|root,COG0288@2|Bacteria,1WKSX@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
CMS1_k127_146098_6	756272.Plabr_2442	1.988e-18	100.0	COG1250@1|root,COG1250@2|Bacteria,2IYHM@203682|Planctomycetes	203682|Planctomycetes	I	3-hydroxyacyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_146098_2	1185876.BN8_01526	8.139e-126	416.0	COG0673@1|root,COG0673@2|Bacteria,4NF3G@976|Bacteroidetes,47MH7@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_146098_0	143224.JQMD01000002_gene1234	1.27e-182	586.0	COG3119@1|root,COG3119@2|Bacteria,4NEBN@976|Bacteroidetes,1HZSK@117743|Flavobacteriia	976|Bacteroidetes	P	sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
CMS1_k127_146098_1	530564.Psta_2900	1.236e-150	496.0	COG3119@1|root,COG3119@2|Bacteria,2IYFZ@203682|Planctomycetes	203682|Planctomycetes	CP	COG3119 Arylsulfatase A	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	HEAT_2,Sulfatase
CMS1_k127_1464583_0	485914.Hmuk_0623	1.316e-80	286.0	COG0673@1|root,arCOG01622@2157|Archaea	2157|Archaea	L	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_1470956_0	251221.35214024	9.295e-137	457.0	COG0591@1|root,COG0591@2|Bacteria,1G1JV@1117|Cyanobacteria	1117|Cyanobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	putP	-	-	-	-	-	-	-	-	-	-	-	SSF
CMS1_k127_1470956_5	443255.SCLAV_p1399	2.534e-35	155.0	28IYT@1|root,2Z8WE@2|Bacteria,2IEQA@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4838)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4838
CMS1_k127_1470956_3	875454.BAEW01000008_gene1211	7.417e-110	373.0	COG3033@1|root,COG3033@2|Bacteria,1TRGV@1239|Firmicutes,248WC@186801|Clostridia,22GQQ@1570339|Peptoniphilaceae	186801|Clostridia	E	Beta-eliminating lyase	tnaA	-	4.1.99.1	ko:K01667	ko00380,map00380	-	R00673	RC00209,RC00355	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
CMS1_k127_1470956_1	251221.35213669	1.863e-120	397.0	COG4948@1|root,COG4948@2|Bacteria,1FZYA@1117|Cyanobacteria	1117|Cyanobacteria	M	Mandelate racemase muconate lactonizing enzyme	-	-	4.2.1.113,5.1.1.20	ko:K02549,ko:K19802	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031,R10938	RC01053,RC03309	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
CMS1_k127_1470956_2	251221.35213670	1.168e-114	381.0	COG3367@1|root,COG3367@2|Bacteria,1G2EW@1117|Cyanobacteria	1117|Cyanobacteria	S	Domain of unknown function (DUF1611_N) Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1611,DUF1611_N
CMS1_k127_1470956_7	247490.KSU1_C1333	9.434e-16	88.0	COG4968@1|root,COG4968@2|Bacteria,2J519@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CMS1_k127_1470956_9	935948.KE386494_gene999	1.125e-06	61.0	COG1609@1|root,COG1609@2|Bacteria,1TT55@1239|Firmicutes,24A7X@186801|Clostridia,42FXB@68295|Thermoanaerobacterales	186801|Clostridia	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
CMS1_k127_1470956_8	649743.HMPREF0972_00646	7.065e-09	68.0	COG2188@1|root,COG2188@2|Bacteria,2GJZ1@201174|Actinobacteria,4D51Y@85005|Actinomycetales	201174|Actinobacteria	K	UbiC transcription regulator-associated domain protein	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
CMS1_k127_1475803_0	330214.NIDE4098	1.082e-13	84.0	COG3217@1|root,COG4726@1|root,COG3217@2|Bacteria,COG4726@2|Bacteria	2|Bacteria	NU	Pilus assembly protein PilX	-	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	DUF3494,MOSC_N
CMS1_k127_147945_2	1237149.C900_04710	3.163e-10	63.0	COG1826@1|root,COG1826@2|Bacteria,4NUNH@976|Bacteroidetes,47S09@768503|Cytophagia	976|Bacteroidetes	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
CMS1_k127_147945_1	1210884.HG799465_gene11558	3.863e-11	76.0	COG1413@1|root,COG1413@2|Bacteria,2J40K@203682|Planctomycetes	203682|Planctomycetes	C	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
CMS1_k127_147945_0	665571.STHERM_c05440	2.31e-123	411.0	COG2204@1|root,COG2204@2|Bacteria,2J5NY@203691|Spirochaetes	203691|Spirochaetes	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	rrp-2	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS1_k127_1502101_14	1379270.AUXF01000002_gene1539	5.444e-14	78.0	2C7E0@1|root,330TX@2|Bacteria,1ZUQG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1502101_19	1165096.ARWF01000001_gene1997	2.868e-05	55.0	COG3637@1|root,COG3637@2|Bacteria,1R64D@1224|Proteobacteria,2W0WB@28216|Betaproteobacteria,2KKXQ@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Alginate export	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp
CMS1_k127_1502101_18	521674.Plim_2317	3.858e-06	59.0	COG3637@1|root,COG3637@2|Bacteria,2IYBM@203682|Planctomycetes	203682|Planctomycetes	M	Alginate export	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp
CMS1_k127_1502101_11	880073.Calab_0696	2.295e-21	107.0	COG1262@1|root,COG2911@1|root,COG3055@1|root,COG3934@1|root,COG5492@1|root,COG1262@2|Bacteria,COG2911@2|Bacteria,COG3055@2|Bacteria,COG3934@2|Bacteria,COG5492@2|Bacteria,2NPU7@2323|unclassified Bacteria	2|Bacteria	G	Sulfatase-modifying factor enzyme 1	-	-	3.2.1.1,3.2.1.51,3.2.1.78,3.2.1.81,3.2.1.89	ko:K01176,ko:K01206,ko:K01218,ko:K01219,ko:K01224	ko00051,ko00500,ko00511,ko01100,ko02024,ko04973,map00051,map00500,map00511,map01100,map02024,map04973	-	R01332,R02108,R02112,R11262	RC00467	ko00000,ko00001,ko01000,ko04147	-	GH13,GH26,GH29	-	Big_2,DctA-YdbH,FGE-sulfatase
CMS1_k127_1502101_17	759362.KVU_1965	1.11e-06	51.0	2ENFV@1|root,33G39@2|Bacteria,1NP5K@1224|Proteobacteria,2UJUH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1502101_2	1267535.KB906767_gene5450	3.061e-141	470.0	COG0673@1|root,COG0673@2|Bacteria,3Y76D@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_1502101_7	313606.M23134_01723	7.342e-66	234.0	COG2454@1|root,COG2454@2|Bacteria,4NN3Y@976|Bacteroidetes,47RKQ@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF434)	-	-	-	-	-	-	-	-	-	-	-	-	DUF434
CMS1_k127_1502101_5	204669.Acid345_3014	1.665e-100	354.0	COG0784@1|root,COG2202@1|root,COG2203@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,3Y64H@57723|Acidobacteria,2JM5F@204432|Acidobacteriia	204432|Acidobacteriia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
CMS1_k127_1502101_12	1123354.AUDR01000013_gene536	2.354e-21	109.0	COG1807@1|root,COG1807@2|Bacteria,1N6KA@1224|Proteobacteria,2VWBM@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS1_k127_1502101_4	761193.Runsl_2560	7.154e-103	343.0	COG3828@1|root,COG3828@2|Bacteria,4PNCT@976|Bacteroidetes,47NTF@768503|Cytophagia	976|Bacteroidetes	S	Methane oxygenase PmoA	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
CMS1_k127_1502101_8	1123242.JH636434_gene4951	2.169e-52	206.0	COG1621@1|root,COG1621@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 32 family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Dockerin_1,HTH_18,RicinB_lectin_2
CMS1_k127_1502101_3	886293.Sinac_0957	1.068e-138	454.0	COG0526@1|root,COG1225@1|root,COG0526@2|Bacteria,COG1225@2|Bacteria,2J1ZV@203682|Planctomycetes	203682|Planctomycetes	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS1_k127_1502101_1	767817.Desgi_4274	2.76e-141	467.0	COG1785@1|root,COG1785@2|Bacteria,1TQCI@1239|Firmicutes,248GG@186801|Clostridia	186801|Clostridia	P	Belongs to the alkaline phosphatase family	-	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase,Cu_amine_oxidN1
CMS1_k127_1502101_10	1173022.Cri9333_0333	5.12e-24	113.0	COG1647@1|root,COG1647@2|Bacteria	2|Bacteria	M	Serine aminopeptidase, S33	-	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_6,Hydrolase_4
CMS1_k127_1502101_0	204669.Acid345_4052	0.0	1048.0	COG0204@1|root,COG0318@1|root,COG0477@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,COG2814@2|Bacteria,3Y4RT@57723|Acidobacteria	57723|Acidobacteria	IQ	Phosphate acyltransferases	-	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase,MFS_1
CMS1_k127_1502101_13	756272.Plabr_1988	4.489e-17	87.0	COG1846@1|root,COG1846@2|Bacteria,2IZDD@203682|Planctomycetes	203682|Planctomycetes	K	COG1846 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
CMS1_k127_1502101_6	1123242.JH636434_gene5529	1.709e-95	321.0	COG1090@1|root,COG1090@2|Bacteria,2IXEW@203682|Planctomycetes	203682|Planctomycetes	S	epimerase	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase,Polyketide_cyc
CMS1_k127_1502101_9	247633.GP2143_04500	1.053e-39	155.0	COG1247@1|root,COG1247@2|Bacteria	2|Bacteria	M	phosphinothricin N-acetyltransferase activity	MA20_16670	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS1_k127_1502101_16	933262.AXAM01000004_gene2370	2.173e-08	61.0	2E3F6@1|root,32YE2@2|Bacteria,1NDBB@1224|Proteobacteria,42WNV@68525|delta/epsilon subdivisions,2WRV2@28221|Deltaproteobacteria,2MKYS@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1510538_3	1123256.KB907933_gene2280	0.0004426	50.0	COG2353@1|root,COG2353@2|Bacteria,1N3P9@1224|Proteobacteria,1SDBE@1236|Gammaproteobacteria,1XAHR@135614|Xanthomonadales	135614|Xanthomonadales	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
CMS1_k127_1510538_1	886293.Sinac_7309	1.305e-67	248.0	COG3828@1|root,COG3828@2|Bacteria	2|Bacteria	N	Trehalose utilisation	-	-	-	ko:K09992	-	-	-	-	ko00000	-	-	-	ThuA
CMS1_k127_1510538_0	583355.Caka_0955	8.386e-107	362.0	COG0673@1|root,COG0673@2|Bacteria,46TMZ@74201|Verrucomicrobia,3K8Y2@414999|Opitutae	414999|Opitutae	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_1510538_2	616991.JPOO01000003_gene2393	2.802e-10	70.0	COG3292@1|root,COG3292@2|Bacteria,4P1XS@976|Bacteroidetes	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1521103_1	1120950.KB892746_gene3435	1.856e-111	388.0	2C33Y@1|root,33VR5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1521103_0	1226325.HMPREF1548_01196	6.185e-125	427.0	28J61@1|root,2Z91S@2|Bacteria,1UYHJ@1239|Firmicutes,24EVG@186801|Clostridia,36HUS@31979|Clostridiaceae	2|Bacteria	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_129
CMS1_k127_1524827_1	1449063.JMLS01000020_gene5317	1.302e-140	454.0	COG1063@1|root,COG1063@2|Bacteria,1TPWP@1239|Firmicutes,4HBN1@91061|Bacilli,26WZN@186822|Paenibacillaceae	91061|Bacilli	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_1524827_4	1173028.ANKO01000153_gene5368	9.341e-36	149.0	COG0667@1|root,COG0667@2|Bacteria,1G2DX@1117|Cyanobacteria,1H8R6@1150|Oscillatoriales	1117|Cyanobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS1_k127_1524827_5	1442598.JABW01000024_gene1549	8.34e-33	130.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,42TPU@68525|delta/epsilon subdivisions,2YPES@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	Belongs to the thioredoxin family	trx	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	iIT341.HP0824	Thioredoxin
CMS1_k127_1524827_7	649831.L083_4472	2.948e-16	85.0	COG3118@1|root,COG3118@2|Bacteria,2IHQV@201174|Actinobacteria	201174|Actinobacteria	O	Thioredoxin	-	-	1.8.1.8	ko:K03672	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Thioredoxin
CMS1_k127_1524827_2	289376.THEYE_A0113	7.01e-133	435.0	COG0136@1|root,COG0136@2|Bacteria,3J0BR@40117|Nitrospirae	40117|Nitrospirae	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
CMS1_k127_1524827_3	1121904.ARBP01000003_gene6571	1.864e-76	271.0	COG1820@1|root,COG1820@2|Bacteria,4NJ35@976|Bacteroidetes,47KJ5@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	-	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
CMS1_k127_1524827_0	926569.ANT_14380	5.593e-156	507.0	COG0624@1|root,COG0624@2|Bacteria,2G5KY@200795|Chloroflexi	200795|Chloroflexi	E	peptidase dimerisation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
CMS1_k127_1524827_6	329726.AM1_2826	3.405e-25	108.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	yprA	-	3.4.11.19	ko:K01266,ko:K07052	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Abi
CMS1_k127_1527129_4	886293.Sinac_5762	1.391e-91	313.0	COG0673@1|root,COG0673@2|Bacteria,2IWRC@203682|Planctomycetes	203682|Planctomycetes	S	COGs COG0673 dehydrogenase and related protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_1527129_8	452637.Oter_0842	1.953e-10	73.0	COG3137@1|root,COG3137@2|Bacteria,46TU0@74201|Verrucomicrobia,3K75A@414999|Opitutae	414999|Opitutae	M	Protein of unknown function, DUF481	-	-	-	-	-	-	-	-	-	-	-	-	DUF481
CMS1_k127_1527129_2	886293.Sinac_5600	1.349e-232	727.0	COG4102@1|root,COG4102@2|Bacteria,2IX5T@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CMS1_k127_1527129_1	886293.Sinac_5601	1.087e-319	1019.0	COG2010@1|root,COG2010@2|Bacteria,2J53S@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
CMS1_k127_1527129_3	1123508.JH636439_gene855	2.07e-154	499.0	COG0823@1|root,COG0823@2|Bacteria,2IZ00@203682|Planctomycetes	203682|Planctomycetes	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
CMS1_k127_1527129_7	1267535.KB906767_gene5001	7.959e-44	184.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,Sulfatase
CMS1_k127_1527129_0	313628.LNTAR_23264	0.0	1313.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria	2|Bacteria	E	methionine synthase	metH	-	2.1.1.13,2.1.1.245,2.1.1.258	ko:K00197,ko:K00548,ko:K15023	ko00270,ko00450,ko00670,ko00680,ko00720,ko01100,ko01110,ko01120,ko01200,ko01230,map00270,map00450,map00670,map00680,map00720,map01100,map01110,map01120,map01200,map01230	M00017,M00357,M00377,M00422	R00946,R02289,R09096,R09365,R10219,R10243	RC00004,RC00035,RC00113,RC01144,RC01241,RC02871,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
CMS1_k127_1527129_9	1254432.SCE1572_02120	1.038e-08	62.0	COG2138@1|root,COG3411@1|root,COG2138@2|Bacteria,COG3411@2|Bacteria,1PRX7@1224|Proteobacteria,42VX1@68525|delta/epsilon subdivisions,2X5BF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	CbiX	-	-	-	-	-	-	-	-	-	-	-	-	CbiX
CMS1_k127_1527129_6	644966.Tmar_1716	7.679e-57	205.0	COG2318@1|root,COG2318@2|Bacteria,1V415@1239|Firmicutes	1239|Firmicutes	S	Protein of unknown function (DUF1572)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1572
CMS1_k127_1528416_1	1206735.BAGG01000011_gene672	3.122e-09	69.0	COG0308@1|root,COG0308@2|Bacteria,2GJWF@201174|Actinobacteria,4FW2B@85025|Nocardiaceae	201174|Actinobacteria	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
CMS1_k127_1528416_0	240016.ABIZ01000001_gene285	1.473e-140	459.0	COG0673@1|root,COG0673@2|Bacteria,46T68@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_1528416_2	1288826.MSNKSG1_12462	6.466e-07	55.0	COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,1RMWU@1236|Gammaproteobacteria,4658B@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	surA	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006457,GO:0006458,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0022607,GO:0030288,GO:0030313,GO:0031647,GO:0031975,GO:0033218,GO:0036211,GO:0042277,GO:0042597,GO:0043163,GO:0043165,GO:0043170,GO:0043412,GO:0044085,GO:0044091,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0044764,GO:0045229,GO:0050821,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0060274,GO:0061024,GO:0061077,GO:0065007,GO:0065008,GO:0071704,GO:0071709,GO:0071840,GO:0140096,GO:1901564	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3,SurA_N
CMS1_k127_1536259_1	1449063.JMLS01000013_gene5979	1.898e-19	100.0	COG1554@1|root,COG1554@2|Bacteria	2|Bacteria	G	hydrolase, family 65, central catalytic	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hyd_65N_2,Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m
CMS1_k127_1536259_0	1207063.P24_06162	6.556e-21	106.0	COG0744@1|root,COG0744@2|Bacteria,1RDAQ@1224|Proteobacteria,2U0NP@28211|Alphaproteobacteria,2JS5A@204441|Rhodospirillales	204441|Rhodospirillales	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
CMS1_k127_1552420_4	1304865.JAGF01000001_gene85	9.554e-80	279.0	COG1960@1|root,COG1960@2|Bacteria,2GKK9@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	fadE10	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,DUF1974
CMS1_k127_1552420_10	66874.JOFS01000001_gene859	5.611e-08	67.0	COG3391@1|root,COG3391@2|Bacteria,2IACT@201174|Actinobacteria	201174|Actinobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	I-set
CMS1_k127_1552420_3	96561.Dole_1791	3.607e-83	314.0	COG1044@1|root,COG1361@1|root,COG1653@1|root,COG1044@2|Bacteria,COG1361@2|Bacteria,COG1653@2|Bacteria,1N4S6@1224|Proteobacteria,43BRE@68525|delta/epsilon subdivisions,2X729@28221|Deltaproteobacteria,2MNRP@213118|Desulfobacterales	1224|Proteobacteria	G	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1552420_9	1198114.AciX9_1126	1.321e-10	76.0	COG3391@1|root,COG5434@1|root,COG3391@2|Bacteria,COG5434@2|Bacteria,3Y2X2@57723|Acidobacteria,2JIFN@204432|Acidobacteriia	204432|Acidobacteriia	M	Glycosyl hydrolases family 28	-	-	3.2.1.15	ko:K01184	ko00040,ko01100,map00040,map01100	M00081	R01982,R02360	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_28,Pectinesterase
CMS1_k127_1552420_8	1313172.YM304_39400	7.292e-27	130.0	COG1357@1|root,COG2834@1|root,COG3210@1|root,COG3391@1|root,COG4932@1|root,COG5184@1|root,COG1357@2|Bacteria,COG2834@2|Bacteria,COG3210@2|Bacteria,COG3391@2|Bacteria,COG4932@2|Bacteria,COG5184@2|Bacteria,2I7X9@201174|Actinobacteria,4CP5M@84992|Acidimicrobiia	2|Bacteria	DMUZ	Domain of unknown function DUF11	espK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03634,ko:K13735,ko:K14166,ko:K18491,ko:K20276	ko02024,ko04550,ko05100,map02024,map04550,map05100	-	-	-	ko00000,ko00001,ko02000,ko03000	-	-	-	CarboxypepD_reg,DUF1566
CMS1_k127_1552420_2	1313172.YM304_39400	5.291e-93	344.0	COG1357@1|root,COG2834@1|root,COG3210@1|root,COG3391@1|root,COG4932@1|root,COG5184@1|root,COG1357@2|Bacteria,COG2834@2|Bacteria,COG3210@2|Bacteria,COG3391@2|Bacteria,COG4932@2|Bacteria,COG5184@2|Bacteria,2I7X9@201174|Actinobacteria,4CP5M@84992|Acidimicrobiia	2|Bacteria	DMUZ	Domain of unknown function DUF11	espK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03634,ko:K13735,ko:K14166,ko:K18491,ko:K20276	ko02024,ko04550,ko05100,map02024,map04550,map05100	-	-	-	ko00000,ko00001,ko02000,ko03000	-	-	-	CarboxypepD_reg,DUF1566
CMS1_k127_1552420_0	1121405.dsmv_0184	5.527e-187	594.0	COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,42NHS@68525|delta/epsilon subdivisions,2WJHI@28221|Deltaproteobacteria,2MIF6@213118|Desulfobacterales	28221|Deltaproteobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	-	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
CMS1_k127_1552420_7	452637.Oter_4579	1.199e-30	123.0	COG3288@1|root,COG3288@2|Bacteria,46T7S@74201|Verrucomicrobia	74201|Verrucomicrobia	C	4TM region of pyridine nucleotide transhydrogenase, mitoch	-	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
CMS1_k127_1552420_1	1121403.AUCV01000007_gene1231	8.945e-155	496.0	COG3288@1|root,COG3288@2|Bacteria,1MVXU@1224|Proteobacteria,42NHC@68525|delta/epsilon subdivisions,2WJQJ@28221|Deltaproteobacteria,2MJKV@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Alanine dehydrogenase/PNT, C-terminal domain	pntA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM
CMS1_k127_1552420_5	1382356.JQMP01000003_gene1359	1.523e-61	238.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2G67H@200795|Chloroflexi,27XI6@189775|Thermomicrobia	189775|Thermomicrobia	T	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
CMS1_k127_1552420_6	886293.Sinac_3224	3.307e-37	160.0	COG0515@1|root,COG0515@2|Bacteria,2IYF2@203682|Planctomycetes	203682|Planctomycetes	KLT	COG0515 Serine threonine protein	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS1_k127_1561835_0	935948.KE386493_gene2375	4.188e-54	212.0	arCOG07336@1|root,2Z8ST@2|Bacteria,1TRXN@1239|Firmicutes,248NM@186801|Clostridia,42HXG@68295|Thermoanaerobacterales	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1563162_2	269799.Gmet_1560	9.802e-20	92.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,42T7G@68525|delta/epsilon subdivisions,2WKC5@28221|Deltaproteobacteria,43TVM@69541|Desulfuromonadales	28221|Deltaproteobacteria	KT	Domain of unknown function (DUF4118)	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GGDEF,HD,HD_5,dCache_2
CMS1_k127_1563162_0	237368.SCABRO_01551	0.0	1846.0	COG3696@1|root,COG3696@2|Bacteria,2IX94@203682|Planctomycetes	203682|Planctomycetes	P	AcrB/AcrD/AcrF family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
CMS1_k127_1563162_1	237368.SCABRO_01550	1.158e-26	116.0	COG0845@1|root,COG0845@2|Bacteria,2IZ22@203682|Planctomycetes	203682|Planctomycetes	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	DUF3347,HlyD_D23
CMS1_k127_156506_0	1303518.CCALI_00669	5.922e-52	203.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Glyco_tranf_2_3,Glycos_transf_2,Sulfatase
CMS1_k127_156506_1	886293.Sinac_2219	7.77e-26	112.0	COG0824@1|root,COG0824@2|Bacteria,2J0QJ@203682|Planctomycetes	203682|Planctomycetes	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT_2
CMS1_k127_156506_2	911008.GLAD_04481	6.527e-05	54.0	COG3210@1|root,COG5492@1|root,COG3210@2|Bacteria,COG5492@2|Bacteria,1R8WN@1224|Proteobacteria,1T0IM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	N	Phage tail tube protein, TTP	-	-	-	-	-	-	-	-	-	-	-	-	Ig_3,Phage_tail_3
CMS1_k127_1566255_0	706587.Desti_0542	2.559e-197	643.0	COG2304@1|root,COG2304@2|Bacteria,1MW8K@1224|Proteobacteria,42NNC@68525|delta/epsilon subdivisions,2WKQW@28221|Deltaproteobacteria,2MQ7A@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
CMS1_k127_1566255_2	111780.Sta7437_3590	1.388e-13	76.0	COG0797@1|root,COG0797@2|Bacteria,1G0XF@1117|Cyanobacteria,3VKBR@52604|Pleurocapsales	1117|Cyanobacteria	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1
CMS1_k127_1566255_1	1499967.BAYZ01000028_gene1316	1.607e-56	209.0	COG1058@1|root,COG1058@2|Bacteria,2NP0G@2323|unclassified Bacteria	2|Bacteria	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
CMS1_k127_1571667_0	641524.ADICYQ_2511	1.818e-102	346.0	2DBQR@1|root,2ZAG2@2|Bacteria,4NK84@976|Bacteroidetes,47NS0@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2
CMS1_k127_1571667_1	1121373.KB903632_gene486	5.14e-31	142.0	COG3291@1|root,COG3405@1|root,COG4447@1|root,COG5520@1|root,COG3291@2|Bacteria,COG3405@2|Bacteria,COG4447@2|Bacteria,COG5520@2|Bacteria	2|Bacteria	M	Belongs to the glycosyl hydrolase 30 family	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CHU_C,Glyco_hydro_9,HYR,PKD
CMS1_k127_1572469_0	1499967.BAYZ01000075_gene2072	8.648e-11	71.0	COG2165@1|root,COG2165@2|Bacteria,2NQ2Y@2323|unclassified Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	pulG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
CMS1_k127_1590232_8	1449126.JQKL01000003_gene1821	2.27e-12	70.0	COG0247@1|root,COG0247@2|Bacteria,1TQJM@1239|Firmicutes,24CFC@186801|Clostridia	186801|Clostridia	C	TIGRFAM glycerol-3-phosphate dehydrogenase, anaerobic, C subunit	glpC	-	1.1.5.3	ko:K00113	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	CCG,Fer4_8
CMS1_k127_1590232_6	1265505.ATUG01000001_gene3022	1.932e-35	141.0	COG0745@1|root,COG0789@1|root,COG0745@2|Bacteria,COG0789@2|Bacteria,1RD9E@1224|Proteobacteria,42PTZ@68525|delta/epsilon subdivisions,2WKZI@28221|Deltaproteobacteria,2MHNV@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17,Response_reg
CMS1_k127_1590232_9	1304875.JAFZ01000004_gene476	1.178e-05	51.0	2DD8T@1|root,2ZH33@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1590232_5	263358.VAB18032_15090	2.1e-37	152.0	COG2199@1|root,COG3706@2|Bacteria,2IABQ@201174|Actinobacteria,4D9W3@85008|Micromonosporales	201174|Actinobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
CMS1_k127_1590232_1	497964.CfE428DRAFT_6043	3.636e-120	400.0	28N13@1|root,2ZB7C@2|Bacteria,46UA3@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
CMS1_k127_1590232_0	1232410.KI421426_gene1341	4.708e-192	630.0	COG1032@1|root,COG5011@1|root,COG1032@2|Bacteria,COG5011@2|Bacteria,1MV5G@1224|Proteobacteria,42MPT@68525|delta/epsilon subdivisions,2WJG9@28221|Deltaproteobacteria,43RXX@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Uncharacterized protein conserved in bacteria (DUF2344)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344,Radical_SAM
CMS1_k127_1590232_3	398525.KB900701_gene2983	1.382e-80	285.0	COG2159@1|root,COG2159@2|Bacteria,1ND2I@1224|Proteobacteria,2UIP1@28211|Alphaproteobacteria,3K498@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CMS1_k127_1590232_4	395493.BegalDRAFT_2588	5.482e-68	241.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,1RPMP@1236|Gammaproteobacteria,460Q6@72273|Thiotrichales	72273|Thiotrichales	O	Peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03773	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
CMS1_k127_1590232_2	756272.Plabr_2335	1.353e-107	354.0	COG2755@1|root,COG2755@2|Bacteria,2IYGD@203682|Planctomycetes	203682|Planctomycetes	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS1_k127_1591476_1	886293.Sinac_3549	1.609e-63	233.0	COG0515@1|root,COG0515@2|Bacteria,2IXXT@203682|Planctomycetes	203682|Planctomycetes	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS1_k127_1591476_0	357808.RoseRS_2336	3.932e-134	431.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS1_k127_1591476_2	273068.TTE1486	5.559e-40	152.0	COG0669@1|root,COG0669@2|Bacteria,1V3MR@1239|Firmicutes,24HC3@186801|Clostridia,42G2R@68295|Thermoanaerobacterales	186801|Clostridia	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
CMS1_k127_1612111_4	394503.Ccel_3233	5.601e-13	75.0	COG2020@1|root,COG2020@2|Bacteria,1V3IZ@1239|Firmicutes,24FW3@186801|Clostridia,36M26@31979|Clostridiaceae	186801|Clostridia	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF218,PEMT
CMS1_k127_1612111_6	1524467.IV04_06045	2.791e-06	60.0	COG0823@1|root,COG0823@2|Bacteria,1MUK9@1224|Proteobacteria,1RNR8@1236|Gammaproteobacteria,402E8@613|Serratia	1236|Gammaproteobacteria	U	Oligogalacturonate lyase	ogl	-	4.2.2.6	ko:K01730	ko00040,map00040	-	R04382	RC02124,RC02427	ko00000,ko00001,ko01000	-	-	-	Pectate_lyase22
CMS1_k127_1612111_5	96561.Dole_0145	6.724e-08	56.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295,PEMT
CMS1_k127_1612111_0	215803.DB30_5051	1.227e-22	101.0	COG2346@1|root,COG2346@2|Bacteria,1Q2G1@1224|Proteobacteria,4382D@68525|delta/epsilon subdivisions,2X3CG@28221|Deltaproteobacteria,2YVEJ@29|Myxococcales	28221|Deltaproteobacteria	C	Bacterial-like globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
CMS1_k127_1612111_2	247490.KSU1_C1333	1.976e-16	91.0	COG4968@1|root,COG4968@2|Bacteria,2J519@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CMS1_k127_1621917_10	469381.Dpep_2382	6.548e-21	105.0	COG1453@1|root,COG1453@2|Bacteria,3T9WQ@508458|Synergistetes	2|Bacteria	C	aldo keto reductase	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17
CMS1_k127_1621917_4	1380600.AUYN01000009_gene1957	1.024e-109	385.0	COG1554@1|root,COG1554@2|Bacteria,4NG60@976|Bacteroidetes,1I057@117743|Flavobacteriia	976|Bacteroidetes	G	hydrolase, family 65, central catalytic	-	-	3.2.1.51	ko:K15923	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	GH95	-	Glyco_hyd_65N_2
CMS1_k127_1621917_1	266117.Rxyl_3138	2.999e-143	462.0	COG1533@1|root,COG1533@2|Bacteria,2GM31@201174|Actinobacteria,4CQAG@84995|Rubrobacteria	84995|Rubrobacteria	L	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
CMS1_k127_1621917_2	305900.GV64_10185	1.989e-133	434.0	COG0491@1|root,COG0491@2|Bacteria,1MWVM@1224|Proteobacteria	1224|Proteobacteria	S	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1621917_7	349106.PsycPRwf_2306	4.213e-54	201.0	COG0300@1|root,COG0300@2|Bacteria,1RG9T@1224|Proteobacteria,1T3RF@1236|Gammaproteobacteria,3NTQP@468|Moraxellaceae	1236|Gammaproteobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS1_k127_1621917_0	443254.Marpi_1332	1.107e-147	479.0	COG2270@1|root,COG2270@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	yxiO	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
CMS1_k127_1621917_5	1303518.CCALI_02179	1.516e-100	335.0	COG1387@1|root,COG1387@2|Bacteria	2|Bacteria	E	zinc ion binding	-	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
CMS1_k127_1621917_6	509190.Cseg_0727	4.763e-60	228.0	COG1680@1|root,COG1680@2|Bacteria,1RHDA@1224|Proteobacteria,2VEYX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS1_k127_1621917_14	1230460.C495_16870	8.584e-11	76.0	arCOG02499@1|root,arCOG02521@1|root,arCOG04500@1|root,arCOG07560@1|root,arCOG02499@2157|Archaea,arCOG02521@2157|Archaea,arCOG04500@2157|Archaea,arCOG07560@2157|Archaea	2157|Archaea	Q	Archaeal Type IV pilin, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CARDB,Glyco_hydro_28,NosD,PKD,Pectate_lyase_3
CMS1_k127_1621917_12	886293.Sinac_6587	4.17e-18	100.0	COG1595@1|root,COG1595@2|Bacteria,2IZMT@203682|Planctomycetes	203682|Planctomycetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS1_k127_1621917_11	497964.CfE428DRAFT_3684	3.935e-20	95.0	COG0071@1|root,COG0071@2|Bacteria,46WRX@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	-	-	-	-	-	-	-	-	-	HSP20
CMS1_k127_1621917_9	671143.DAMO_2768	1.863e-32	132.0	COG0071@1|root,COG0071@2|Bacteria,2NPWF@2323|unclassified Bacteria	2|Bacteria	O	Belongs to the small heat shock protein (HSP20) family	hspA-1	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
CMS1_k127_1621917_16	436229.JOEH01000001_gene1658	0.0006203	52.0	COG1807@1|root,COG1807@2|Bacteria,2GJPU@201174|Actinobacteria,2NF9Y@228398|Streptacidiphilus	201174|Actinobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS1_k127_1621917_8	756272.Plabr_1201	1.985e-50	188.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG3828@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,COG3828@2|Bacteria,2IXKV@203682|Planctomycetes	203682|Planctomycetes	C	Membrane-bound dehydrogenase domain	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DUF1080,GSDH,NPCBM,ThuA
CMS1_k127_1621917_13	1234364.AMSF01000016_gene1577	1.778e-11	72.0	COG1595@1|root,COG1595@2|Bacteria,1N38X@1224|Proteobacteria,1S8HN@1236|Gammaproteobacteria,1X62E@135614|Xanthomonadales	135614|Xanthomonadales	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS1_k127_1621917_3	641524.ADICYQ_3327	2.888e-131	434.0	COG1621@1|root,COG1621@2|Bacteria,4NJ89@976|Bacteroidetes	976|Bacteroidetes	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1621917_15	530564.Psta_4311	2.725e-06	49.0	COG3386@1|root,COG3386@2|Bacteria,2IXWY@203682|Planctomycetes	203682|Planctomycetes	G	gluconolactonase	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
CMS1_k127_1627547_0	373903.Hore_16450	7.494e-255	798.0	COG1304@1|root,COG1304@2|Bacteria,1TPC5@1239|Firmicutes,247PK@186801|Clostridia,3WBI0@53433|Halanaerobiales	186801|Clostridia	C	PFAM Conserved region in glutamate synthase	-	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase
CMS1_k127_1627547_1	479433.Caci_3523	7.987e-44	175.0	COG1080@1|root,COG1080@2|Bacteria,2IBFB@201174|Actinobacteria	201174|Actinobacteria	G	PEP-utilising enzyme, TIM barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	PEP-utilizers,PEP-utilizers_C
CMS1_k127_1628484_14	794903.OPIT5_01535	1.075e-07	65.0	COG1874@1|root,COG1874@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	3.2.1.23	ko:K12308,ko:K21000	ko00052,ko02025,map00052,map02025	-	R01105	RC00452	ko00000,ko00001,ko01000	-	GH39	-	Glyco_hydro_42
CMS1_k127_1628484_16	1283284.AZUK01000001_gene897	9.601e-07	61.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,1RN3Z@1236|Gammaproteobacteria,1Y3NV@135624|Aeromonadales	135624|Aeromonadales	U	type IV pilus secretin PilQ	-	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
CMS1_k127_1628484_11	765912.Thimo_0087	1.568e-22	111.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,1RN3Z@1236|Gammaproteobacteria,1WWYN@135613|Chromatiales	135613|Chromatiales	U	type IV pilus secretin PilQ	-	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
CMS1_k127_1628484_6	338963.Pcar_1236	1.386e-66	246.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,42MPS@68525|delta/epsilon subdivisions,2WIUD@28221|Deltaproteobacteria,43TZX@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Carbon-nitrogen hydrolase	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
CMS1_k127_1628484_4	1131269.AQVV01000003_gene666	3.956e-81	290.0	COG0728@1|root,COG0728@2|Bacteria	2|Bacteria	M	peptidoglycan biosynthetic process	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
CMS1_k127_1628484_15	1205753.A989_09106	1.351e-07	62.0	COG5126@1|root,COG5126@2|Bacteria,1NH5D@1224|Proteobacteria,1SGAQ@1236|Gammaproteobacteria,1XC2D@135614|Xanthomonadales	135614|Xanthomonadales	DTZ	EF-hand domain pair	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_5
CMS1_k127_1628484_5	946362.XP_004991886.1	3.484e-67	247.0	COG0153@1|root,KOG0631@2759|Eukaryota,38ESX@33154|Opisthokonta	33154|Opisthokonta	G	galactokinase activity	GALK2	GO:0000409,GO:0000411,GO:0000429,GO:0000431,GO:0000435,GO:0000436,GO:0003674,GO:0003824,GO:0004335,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005975,GO:0005996,GO:0006012,GO:0006355,GO:0006357,GO:0006793,GO:0006796,GO:0007154,GO:0007584,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009605,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019219,GO:0019222,GO:0019318,GO:0019320,GO:0019388,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0031982,GO:0033036,GO:0033499,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043230,GO:0043231,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044421,GO:0044424,GO:0044464,GO:0045185,GO:0045893,GO:0045935,GO:0045944,GO:0045990,GO:0045991,GO:0046365,GO:0046835,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051179,GO:0051235,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0065008,GO:0070062,GO:0070887,GO:0071496,GO:0071704,GO:0080090,GO:1901575,GO:1902680,GO:1903506,GO:1903508,GO:1903561,GO:2000112,GO:2001141	2.7.1.157,2.7.1.6	ko:K00849,ko:K17781,ko:K18674	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko02000,ko03029,ko04147	3.A.8.1	-	iMM904.YBR020W,iND750.YBR020W	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
CMS1_k127_1628484_13	443143.GM18_2812	1.229e-08	66.0	2DXYI@1|root,34771@2|Bacteria,1P0DZ@1224|Proteobacteria,431TH@68525|delta/epsilon subdivisions,2WX2S@28221|Deltaproteobacteria,43VCH@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1628484_8	349741.Amuc_1856	6.429e-51	190.0	COG0639@1|root,COG0639@2|Bacteria,46TA5@74201|Verrucomicrobia,2ITKJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
CMS1_k127_1628484_1	667014.Thein_1073	1.28e-119	393.0	COG0232@1|root,COG0232@2|Bacteria,2GH8D@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	F	Phosphohydrolase-associated domain	-	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
CMS1_k127_1628484_10	1123508.JH636440_gene2782	4.699e-32	134.0	COG0005@1|root,COG0005@2|Bacteria,2J2XX@203682|Planctomycetes	203682|Planctomycetes	F	Phosphorylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PNP_UDP_1
CMS1_k127_1628484_9	880073.Calab_0900	8.054e-38	151.0	COG2078@1|root,COG2078@2|Bacteria,2NPQ0@2323|unclassified Bacteria	2|Bacteria	S	AMMECR1	-	-	-	ko:K06990,ko:K09141	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,Memo
CMS1_k127_1628484_12	1158165.KB898879_gene2671	1.289e-20	105.0	COG1355@1|root,COG1355@2|Bacteria,1MXK5@1224|Proteobacteria,1RQPK@1236|Gammaproteobacteria,1WX63@135613|Chromatiales	135613|Chromatiales	S	Belongs to the MEMO1 family	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
CMS1_k127_1628484_2	269797.Mbar_A0031	7.555e-100	338.0	arCOG07799@1|root,arCOG07799@2157|Archaea	2157|Archaea	S	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	DUF3880,Glyco_trans_1_2,Glycos_transf_2
CMS1_k127_1628484_0	555088.DealDRAFT_2165	1.31e-198	639.0	COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes,247N4@186801|Clostridia,42JHA@68298|Syntrophomonadaceae	186801|Clostridia	J	elongation factor Tu domain 2 protein	fusA2	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
CMS1_k127_1628484_17	886293.Sinac_6346	0.0001959	47.0	2EUTQ@1|root,33N99@2|Bacteria,2J1AA@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1628484_19	1009370.ALO_05785	0.0006665	53.0	2EDFC@1|root,33KX3@2|Bacteria,1VKNQ@1239|Firmicutes,4H6WB@909932|Negativicutes	909932|Negativicutes	S	Helicase conserved C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C_3
CMS1_k127_1628484_18	414996.IL38_15665	0.0002913	54.0	COG2378@1|root,COG2378@2|Bacteria,2GMAU@201174|Actinobacteria,4088Z@622450|Actinopolysporales	201174|Actinobacteria	K	WYL domain	pafC	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K13573	-	-	-	-	ko00000,ko03051	-	-	-	WYL
CMS1_k127_1628484_3	1123242.JH636435_gene2842	4.384e-84	291.0	COG1940@1|root,COG1940@2|Bacteria,2IY6I@203682|Planctomycetes	203682|Planctomycetes	GK	PFAM ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
CMS1_k127_1628484_7	1499967.BAYZ01000153_gene1551	1.348e-52	190.0	COG2373@1|root,COG2373@2|Bacteria	2|Bacteria	U	Large extracellular alpha-helical protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,A2M_comp,A2M_recep,CarboxypepD_reg,Plug,Thiol-ester_cl
CMS1_k127_164381_2	944481.JAFP01000001_gene1269	2.254e-19	98.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,42U0T@68525|delta/epsilon subdivisions,2WQ7I@28221|Deltaproteobacteria,2M76J@213113|Desulfurellales	28221|Deltaproteobacteria	O	CS domain	hspA-1	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
CMS1_k127_164381_1	243233.MCA1778	7.848e-93	315.0	COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,1RQWB@1236|Gammaproteobacteria,1XDYN@135618|Methylococcales	135618|Methylococcales	O	Cytochrome oxidase assembly	-	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
CMS1_k127_164381_0	765420.OSCT_2823	2.545e-153	497.0	COG0493@1|root,COG0493@2|Bacteria,2G6SR@200795|Chloroflexi,374Z6@32061|Chloroflexia	32061|Chloroflexia	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	Pyr_redox_2
CMS1_k127_1647150_0	1122931.AUAE01000007_gene1342	1.113e-267	861.0	COG0457@1|root,COG0457@2|Bacteria,4NKMF@976|Bacteroidetes,2FXC5@200643|Bacteroidia,231HD@171551|Porphyromonadaceae	1122931.AUAE01000007_gene1342|-	S	Domain of unknown function (DUF5107)	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1647150_1	278957.ABEA03000202_gene4286	3.334e-141	470.0	2A266@1|root,30QGS@2|Bacteria,46Y1D@74201|Verrucomicrobia,3K8SA@414999|Opitutae	414999|Opitutae	S	Heparinase II/III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III
CMS1_k127_1647150_2	1340493.JNIF01000003_gene3494	7.16e-46	186.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	3.1.1.102	ko:K06978,ko:K21105	-	-	R11541	RC00020,RC00041	ko00000,ko01000	-	-	-	AXE1,Big_5,LTD,Peptidase_S9,Tannase
CMS1_k127_1647579_9	523791.Kkor_1953	4.044e-06	51.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,1RPCB@1236|Gammaproteobacteria,1XHZT@135619|Oceanospirillales	135619|Oceanospirillales	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
CMS1_k127_1647579_0	1499967.BAYZ01000157_gene597	1.928e-173	553.0	COG1219@1|root,COG1219@2|Bacteria,2NNN2@2323|unclassified Bacteria	2|Bacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
CMS1_k127_1647579_2	635013.TherJR_2563	2.459e-88	295.0	COG0740@1|root,COG0740@2|Bacteria,1TQ91@1239|Firmicutes,247QY@186801|Clostridia,260UI@186807|Peptococcaceae	186801|Clostridia	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
CMS1_k127_1647579_3	1121324.CLIT_23c00980	1.866e-60	228.0	COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia	186801|Clostridia	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
CMS1_k127_1647579_7	1120963.KB894491_gene1107	1.514e-07	56.0	2DE24@1|root,2ZK69@2|Bacteria,1P9N5@1224|Proteobacteria,1SU0Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1647579_1	1122925.KB895381_gene3822	1.117e-119	402.0	COG1070@1|root,COG1070@2|Bacteria,1UYIG@1239|Firmicutes,4HUWR@91061|Bacilli,26UUE@186822|Paenibacillaceae	91061|Bacilli	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
CMS1_k127_1647579_5	1255043.TVNIR_1227	2.248e-42	164.0	COG1376@1|root,COG1376@2|Bacteria,1MYZT@1224|Proteobacteria,1S8PS@1236|Gammaproteobacteria,1WY8E@135613|Chromatiales	135613|Chromatiales	S	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
CMS1_k127_1647579_4	344747.PM8797T_07909	1.435e-55	208.0	COG4968@1|root,COG4968@2|Bacteria,2J519@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CMS1_k127_1661258_1	1121405.dsmv_2499	3.315e-79	269.0	COG1397@1|root,COG1397@2|Bacteria,1NTUR@1224|Proteobacteria,42NWG@68525|delta/epsilon subdivisions,2WKEU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM ADP-ribosylation Crystallin J1	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
CMS1_k127_1661258_0	298655.KI912266_gene5856	1.172e-142	483.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,2GKFE@201174|Actinobacteria,4ESHW@85013|Frankiales	201174|Actinobacteria	C	PFAM Transketolase central region	bkdA	-	1.2.4.4	ko:K11381,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
CMS1_k127_1665533_2	1121438.JNJA01000006_gene236	8.02e-34	136.0	COG0500@1|root,COG2226@2|Bacteria,1RKJ7@1224|Proteobacteria,42T77@68525|delta/epsilon subdivisions,2WT2E@28221|Deltaproteobacteria,2M8S2@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS1_k127_1665533_4	404589.Anae109_3838	1.583e-20	107.0	COG1409@1|root,COG1409@2|Bacteria,1NS3S@1224|Proteobacteria,43AFC@68525|delta/epsilon subdivisions,2X64J@28221|Deltaproteobacteria,2Z0UN@29|Myxococcales	28221|Deltaproteobacteria	G	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
CMS1_k127_1665533_6	1123508.JH636439_gene1468	5.35e-07	60.0	COG0515@1|root,COG3642@1|root,COG0515@2|Bacteria,COG3642@2|Bacteria,2IZTN@203682|Planctomycetes	203682|Planctomycetes	KLT	Lipopolysaccharide kinase (Kdo/WaaP) family	-	-	-	-	-	-	-	-	-	-	-	-	Kdo
CMS1_k127_1665533_3	1238190.AMQY01000003_gene1645	6.612e-24	113.0	COG3642@1|root,COG3642@2|Bacteria,1RDW7@1224|Proteobacteria,1S46R@1236|Gammaproteobacteria,1XK5R@135619|Oceanospirillales	135619|Oceanospirillales	H	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position	kdkA	-	2.7.1.166	ko:K11211	ko00540,map00540	-	R09767	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	Kdo
CMS1_k127_1665533_5	671143.DAMO_0811	5.391e-20	102.0	COG0721@1|root,COG0721@2|Bacteria,2NPXC@2323|unclassified Bacteria	2|Bacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
CMS1_k127_1665533_0	671143.DAMO_0810	1.429e-188	601.0	COG0154@1|root,COG0154@2|Bacteria,2NNSD@2323|unclassified Bacteria	2|Bacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	GO:0008150,GO:0040007	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
CMS1_k127_1665533_1	1094508.Tsac_2558	3.846e-114	374.0	COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,247MS@186801|Clostridia,42F1D@68295|Thermoanaerobacterales	186801|Clostridia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
CMS1_k127_1674530_0	357808.RoseRS_4085	1.291e-81	279.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS1_k127_1674530_1	641143.HMPREF9331_01992	8.802e-15	83.0	COG2353@1|root,COG2353@2|Bacteria,4NMFT@976|Bacteroidetes,1I1D2@117743|Flavobacteriia,1ER2R@1016|Capnocytophaga	976|Bacteroidetes	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
CMS1_k127_1675073_0	935948.KE386494_gene320	2.155e-169	537.0	COG0407@1|root,COG0407@2|Bacteria,1UZSW@1239|Firmicutes,24E13@186801|Clostridia,42IBM@68295|Thermoanaerobacterales	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
CMS1_k127_1675073_1	794903.OPIT5_10915	2.189e-152	506.0	COG0591@1|root,COG0591@2|Bacteria	2|Bacteria	E	symporter activity	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
CMS1_k127_1675073_2	717606.PaecuDRAFT_2033	3.071e-53	198.0	COG1361@1|root,COG3291@1|root,COG1361@2|Bacteria,COG3291@2|Bacteria,1UKER@1239|Firmicutes,4HFP1@91061|Bacilli	91061|Bacilli	M	TIGRFAM conserved repeat domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
CMS1_k127_168574_0	1379698.RBG1_1C00001G0844	2.062e-165	533.0	COG0215@1|root,COG0215@2|Bacteria,2NNP0@2323|unclassified Bacteria	2|Bacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:2001065	6.1.1.16,6.3.1.13	ko:K01883,ko:K15526	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iECUMN_1333.ECUMN_0566,iJN746.PP_2905,iNJ661.Rv2130c	DALR_2,tRNA-synt_1e,tRNA-synt_1g
CMS1_k127_168574_5	1121422.AUMW01000024_gene240	1.307e-32	136.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,262RV@186807|Peptococcaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	algU	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_168574_10	344747.PM8797T_24726	6.562e-05	55.0	COG1621@1|root,COG1621@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 32 family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,HTH_18
CMS1_k127_168574_6	1142394.PSMK_10630	2.384e-22	106.0	COG2335@1|root,COG2335@2|Bacteria,2IZDI@203682|Planctomycetes	203682|Planctomycetes	M	COG2335 Secreted and surface protein containing fasciclin-like repeats	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
CMS1_k127_168574_2	1123508.JH636443_gene4935	5.114e-58	218.0	COG1408@1|root,COG1408@2|Bacteria,2J015@203682|Planctomycetes	203682|Planctomycetes	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
CMS1_k127_168574_4	521674.Plim_0560	1.428e-37	145.0	COG1832@1|root,COG1832@2|Bacteria,2J066@203682|Planctomycetes	203682|Planctomycetes	S	CoA-binding protein	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
CMS1_k127_168574_7	192952.MM_0936	6.871e-12	74.0	arCOG06818@1|root,arCOG06818@2157|Archaea,2Y20V@28890|Euryarchaeota,2NB84@224756|Methanomicrobia	224756|Methanomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_168574_8	926550.CLDAP_34290	9.718e-08	66.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	ASH,Big_3_2,Cadherin-like,Calx-beta,DUF11,DUF4347,DUF4430,DUF915,FTP,HYR,I-set,PQQ_2,PT-HINT,Peptidase_M36,Pro-kuma_activ,RHS_repeat,VCBS
CMS1_k127_168574_11	29760.VIT_08s0007g01790.t01	0.0001675	55.0	2CMU7@1|root,2QRZ6@2759|Eukaryota,37MS8@33090|Viridiplantae,3GF9D@35493|Streptophyta	35493|Streptophyta	S	Defective in exine formation	-	GO:0003674,GO:0005488,GO:0005509,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0007275,GO:0008150,GO:0009555,GO:0009653,GO:0009987,GO:0010208,GO:0010584,GO:0010927,GO:0012505,GO:0016020,GO:0016043,GO:0022607,GO:0030198,GO:0032501,GO:0032502,GO:0032989,GO:0043062,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0045229,GO:0046872,GO:0048229,GO:0048646,GO:0048856,GO:0048869,GO:0071840,GO:0085029	-	-	-	-	-	-	-	-	-	-	FG-GAP,VCBS
CMS1_k127_168574_1	1123371.ATXH01000019_gene615	1.353e-110	366.0	COG1087@1|root,COG1087@2|Bacteria,2GIQU@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	Male sterility protein	-	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
CMS1_k127_168574_9	1123242.JH636434_gene5474	3.749e-06	59.0	COG1196@1|root,COG1196@2|Bacteria,2IYM0@203682|Planctomycetes	203682|Planctomycetes	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_168574_3	314230.DSM3645_08622	9.873e-55	204.0	COG3391@1|root,COG3391@2|Bacteria,2IYRP@203682|Planctomycetes	203682|Planctomycetes	P	RING finger protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,NHL
CMS1_k127_1686733_2	913865.DOT_4404	1.79e-08	59.0	COG0004@1|root,COG0004@2|Bacteria,1TQYG@1239|Firmicutes,247W1@186801|Clostridia,2615C@186807|Peptococcaceae	186801|Clostridia	P	TIGRFAM Ammonium transporter	amt	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp,P-II
CMS1_k127_1686733_0	644282.Deba_1149	1.404e-44	173.0	2BCS0@1|root,303C3@2|Bacteria,1N7SU@1224|Proteobacteria,42WF2@68525|delta/epsilon subdivisions,2WR6I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Gcw_chp
CMS1_k127_1686733_1	935863.AWZR01000001_gene1706	4.481e-14	75.0	COG1819@1|root,COG1819@2|Bacteria,1MVI7@1224|Proteobacteria,1S57B@1236|Gammaproteobacteria,1X5IY@135614|Xanthomonadales	135614|Xanthomonadales	CG	Glycosyl transferases, related to UDP-glucuronosyltransferase	ugt	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_28,UDPGT
CMS1_k127_1686845_9	926550.CLDAP_28230	8.05e-29	129.0	COG0006@1|root,COG0006@2|Bacteria,2G6N9@200795|Chloroflexi	200795|Chloroflexi	E	Metallopeptidase family M24	-	-	-	ko:K18829	-	-	-	-	ko00000,ko02048	-	-	-	Peptidase_M24
CMS1_k127_1686845_10	243924.LT42_22490	4.126e-12	78.0	COG0438@1|root,COG0438@2|Bacteria,1N9EV@1224|Proteobacteria,1RYRV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	glycosyl transferase group 1	-	-	2.4.1.349	ko:K12994	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glyco_transf_4,Glycos_transf_1
CMS1_k127_1686845_1	886293.Sinac_5883	1.387e-159	515.0	COG3119@1|root,COG3379@1|root,COG3119@2|Bacteria,COG3379@2|Bacteria,2IYF3@203682|Planctomycetes	203682|Planctomycetes	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
CMS1_k127_1686845_6	1167006.UWK_01300	2.186e-82	288.0	COG1639@1|root,COG2204@1|root,COG1639@2|Bacteria,COG2204@2|Bacteria,1R6YN@1224|Proteobacteria,42Q4G@68525|delta/epsilon subdivisions,2WJM9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HDOD,Response_reg
CMS1_k127_1686845_2	237368.SCABRO_02339	1.325e-117	389.0	COG3437@1|root,COG3437@2|Bacteria,2IYS1@203682|Planctomycetes	203682|Planctomycetes	T	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
CMS1_k127_1686845_3	1121459.AQXE01000005_gene1544	3.009e-97	332.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PGC@68525|delta/epsilon subdivisions,2WKHK@28221|Deltaproteobacteria,2MHHP@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	FHA,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg,dCache_3
CMS1_k127_1686845_7	661478.OP10G_0711	9.506e-63	226.0	COG5285@1|root,COG5285@2|Bacteria	2|Bacteria	Q	dioxygenase activity	-	-	1.14.11.18	ko:K00477	ko04146,map04146	-	-	-	ko00000,ko00001,ko01000	-	-	-	PhyH
CMS1_k127_1686845_4	661478.OP10G_3652	1.606e-91	326.0	COG2008@1|root,COG2008@2|Bacteria	2|Bacteria	E	L-allo-threonine aldolase activity	ltaE	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	iLJ478.TM1744	Beta_elim_lyase
CMS1_k127_1686845_0	667014.Thein_0901	8.122e-193	623.0	COG0445@1|root,COG0445@2|Bacteria,2GHNC@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
CMS1_k127_1686845_8	1395587.P364_0116460	1.804e-31	131.0	COG0454@1|root,COG0456@2|Bacteria,1V5BE@1239|Firmicutes,4HHNK@91061|Bacilli,26XNW@186822|Paenibacillaceae	91061|Bacilli	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS1_k127_1686845_11	401053.AciPR4_2567	5.273e-07	61.0	COG0622@1|root,COG0622@2|Bacteria,3Y51P@57723|Acidobacteria,2JJEG@204432|Acidobacteriia	204432|Acidobacteriia	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
CMS1_k127_1686845_5	518766.Rmar_1256	2.657e-89	304.0	COG0053@1|root,COG0053@2|Bacteria,4NEID@976|Bacteroidetes,1FJ56@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	fieF	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
CMS1_k127_1688878_1	641524.ADICYQ_5484	1.068e-84	285.0	COG3386@1|root,COG3386@2|Bacteria,4NH7B@976|Bacteroidetes,47KJ7@768503|Cytophagia	976|Bacteroidetes	G	BNR repeat-containing family member	-	-	-	-	-	-	-	-	-	-	-	-	BNR_4
CMS1_k127_1688878_2	517418.Ctha_0845	1.69e-17	98.0	COG0823@1|root,COG5184@1|root,COG0823@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	ko:K13669	-	-	-	-	ko00000,ko01000,ko01003	-	GT87	-	Cadherin-like,GT87,PD40
CMS1_k127_1688878_0	926569.ANT_27970	2.26e-88	329.0	COG3227@1|root,COG4412@1|root,COG3227@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	3.4.21.50,3.4.24.28	ko:K01337,ko:K01400,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF4968,DUF5110,F5_F8_type_C,FTP,Glyco_hydro_31,PA,Peptidase_M4,Peptidase_M4_C,Peptidase_M6,Peptidase_S8,W_rich_C
CMS1_k127_1688878_3	547559.Nmag_3437	5.703e-10	71.0	COG2244@1|root,arCOG02209@2157|Archaea,2XVSG@28890|Euryarchaeota,23TS7@183963|Halobacteria	183963|Halobacteria	S	Membrane protein involved in the export of O-antigen and teichoic acid	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
CMS1_k127_1723555_1	1380387.JADM01000016_gene3783	7.268e-114	378.0	COG3386@1|root,COG3386@2|Bacteria,1MX7V@1224|Proteobacteria,1RMQK@1236|Gammaproteobacteria,1XJKP@135619|Oceanospirillales	135619|Oceanospirillales	G	Gluconolactonase	-	-	-	-	-	-	-	-	-	-	-	-	Str_synth
CMS1_k127_1723555_7	373903.Hore_13810	1.202e-13	77.0	COG2250@1|root,COG2250@2|Bacteria,1VH7U@1239|Firmicutes,24TC7@186801|Clostridia	186801|Clostridia	S	PFAM HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
CMS1_k127_1723555_0	530564.Psta_4755	2.423e-223	707.0	COG1164@1|root,COG1164@2|Bacteria,2IWWZ@203682|Planctomycetes	203682|Planctomycetes	E	oligoendopeptidase F	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
CMS1_k127_1723555_8	1408473.JHXO01000006_gene1427	8.685e-07	61.0	COG3669@1|root,COG3934@1|root,COG3669@2|Bacteria,COG3934@2|Bacteria,4NZYV@976|Bacteroidetes,2FWVF@200643|Bacteroidia	976|Bacteroidetes	G	Alpha-L-fucosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1723555_3	1304880.JAGB01000002_gene2405	3.191e-72	256.0	COG1082@1|root,COG1082@2|Bacteria,1UNKF@1239|Firmicutes	1239|Firmicutes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS1_k127_1723555_4	1303518.CCALI_01071	1.26e-71	255.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	1.1.1.18,1.1.1.369	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	-	R01183,R09951	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_1723555_2	358681.BBR47_17150	2.968e-101	339.0	COG0673@1|root,COG0673@2|Bacteria,1TP83@1239|Firmicutes,4HBTY@91061|Bacilli,26SY9@186822|Paenibacillaceae	91061|Bacilli	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_1723555_5	1121930.AQXG01000002_gene2294	1.317e-47	182.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
CMS1_k127_1723555_6	1449063.JMLS01000003_gene2092	3.321e-28	121.0	COG1082@1|root,COG1082@2|Bacteria,1UYRD@1239|Firmicutes,4I74C@91061|Bacilli,26VZH@186822|Paenibacillaceae	91061|Bacilli	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS1_k127_1745618_4	880073.Calab_0119	4.075e-06	57.0	2F9BU@1|root,341NU@2|Bacteria,2NR9C@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1745618_3	1461580.CCAS010000054_gene3691	8.931e-07	52.0	29SB3@1|root,30DFK@2|Bacteria,1UB8Q@1239|Firmicutes,4IMMG@91061|Bacilli,1ZKF6@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1745618_5	888439.HMPREF9240_00488	0.0001175	47.0	2E4EA@1|root,3068J@2|Bacteria,2GZWZ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1745618_0	1150469.RSPPHO_03247	1.937e-40	151.0	2DMNG@1|root,32SP1@2|Bacteria,1NAN7@1224|Proteobacteria,2UD5X@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1745618_2	1122971.BAME01000208_gene6775	7.301e-22	96.0	2DMHR@1|root,32RMI@2|Bacteria,4NUR9@976|Bacteroidetes,2FT84@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1745618_1	428125.CLOLEP_01442	1.029e-33	132.0	2AETI@1|root,314QM@2|Bacteria,1U3Z2@1239|Firmicutes,259TM@186801|Clostridia,3WQNX@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1748960_7	765910.MARPU_10745	3.481e-124	403.0	COG2878@1|root,COG2878@2|Bacteria,1NZIR@1224|Proteobacteria,1RPC4@1236|Gammaproteobacteria,1WWC5@135613|Chromatiales	135613|Chromatiales	C	Fe-S cluster	-	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4
CMS1_k127_1748960_0	1239962.C943_00084	0.0	2256.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1141@1|root,COG1145@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1141@2|Bacteria,COG1145@2|Bacteria,COG1146@2|Bacteria,4NF4F@976|Bacteroidetes	976|Bacteroidetes	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
CMS1_k127_1748960_3	768671.ThimaDRAFT_3829	1.37e-183	584.0	COG4656@1|root,COG4656@2|Bacteria,1QTUI@1224|Proteobacteria,1RMIM@1236|Gammaproteobacteria,1WXET@135613|Chromatiales	135613|Chromatiales	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4_8,RnfC_N,SLBB
CMS1_k127_1748960_6	2340.JV46_16920	4.547e-127	417.0	COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,1RMEU@1236|Gammaproteobacteria,1J55P@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Part of a membrane complex involved in electron transport	rnfD	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
CMS1_k127_1748960_12	1049564.TevJSym_br00050	3.257e-55	205.0	COG4659@1|root,COG4659@2|Bacteria,1R6FE@1224|Proteobacteria,1RYZ7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Part of a membrane complex involved in electron transport	-	-	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
CMS1_k127_1748960_11	765911.Thivi_3184	1.46e-74	258.0	COG4660@1|root,COG4660@2|Bacteria,1R342@1224|Proteobacteria,1T62W@1236|Gammaproteobacteria,1WW5Q@135613|Chromatiales	135613|Chromatiales	U	Part of a membrane complex involved in electron transport	-	-	-	ko:K03613	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
CMS1_k127_1748960_10	1250005.PHEL85_1699	9.115e-75	264.0	COG4657@1|root,COG4657@2|Bacteria,4PPXA@976|Bacteroidetes,1I9U6@117743|Flavobacteriia	976|Bacteroidetes	U	Part of a membrane complex involved in electron transport	-	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
CMS1_k127_1748960_15	945713.IALB_1819	4.668e-34	142.0	COG1410@1|root,COG1410@2|Bacteria	2|Bacteria	E	methionine synthase	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Met_synt_B12
CMS1_k127_1748960_9	1235803.C825_01631	2.003e-85	288.0	COG5012@1|root,COG5012@2|Bacteria,4P1N8@976|Bacteroidetes,2G2FS@200643|Bacteroidia	976|Bacteroidetes	S	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
CMS1_k127_1748960_2	1304880.JAGB01000001_gene542	2.671e-189	595.0	COG0407@1|root,COG0407@2|Bacteria,1UZD2@1239|Firmicutes,24C43@186801|Clostridia	186801|Clostridia	H	PFAM Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
CMS1_k127_1748960_8	632518.Calow_2148	3.833e-107	361.0	COG0407@1|root,COG0407@2|Bacteria,1UY51@1239|Firmicutes,24DZF@186801|Clostridia,42FW9@68295|Thermoanaerobacterales	186801|Clostridia	H	PFAM Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
CMS1_k127_1748960_5	697281.Mahau_0028	8.057e-150	480.0	COG0407@1|root,COG0407@2|Bacteria,1V5JE@1239|Firmicutes,24E5A@186801|Clostridia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
CMS1_k127_1748960_14	1173023.KE650771_gene530	3.686e-35	136.0	2CCSR@1|root,32RWC@2|Bacteria,1GA04@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM S23 ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
CMS1_k127_1748960_19	439235.Dalk_3916	5.591e-21	99.0	COG0642@1|root,COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,1NRP8@1224|Proteobacteria,42MW4@68525|delta/epsilon subdivisions,2WKWD@28221|Deltaproteobacteria,2MHPK@213118|Desulfobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,GAF_2,HAMP,HATPase_c,HisKA,Response_reg
CMS1_k127_1748960_16	530564.Psta_2465	5.858e-26	118.0	COG0811@1|root,COG0811@2|Bacteria,2IZ3U@203682|Planctomycetes	203682|Planctomycetes	U	MotA TolQ ExbB proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
CMS1_k127_1748960_20	2340.JV46_08360	1.006e-09	65.0	COG0848@1|root,COG0848@2|Bacteria,1PQKY@1224|Proteobacteria,1SG1V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	biopolymer transport protein	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
CMS1_k127_1748960_18	1223410.KN050846_gene1156	3.115e-22	113.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,4NE4W@976|Bacteroidetes,1HX2D@117743|Flavobacteriia	976|Bacteroidetes	K	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_21,TPR_6,TPR_8
CMS1_k127_1748960_13	1499967.BAYZ01000173_gene5813	1.915e-41	173.0	COG2304@1|root,COG2304@2|Bacteria,2NPZM@2323|unclassified Bacteria	2|Bacteria	S	Vault protein inter-alpha-trypsin domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	FecR,VIT,VWA,VWA_3
CMS1_k127_1748960_17	1499967.BAYZ01000069_gene1854	9.688e-24	117.0	COG0153@1|root,COG0153@2|Bacteria,2NNYM@2323|unclassified Bacteria	2|Bacteria	G	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
CMS1_k127_1748960_1	234267.Acid_0200	2.669e-267	854.0	COG3661@1|root,COG3661@2|Bacteria,3Y3Q5@57723|Acidobacteria	57723|Acidobacteria	G	Belongs to the glycosyl hydrolase 67 family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1748960_22	639282.DEFDS_0849	8.272e-05	52.0	COG0664@1|root,COG0664@2|Bacteria,2GG6E@200930|Deferribacteres	200930|Deferribacteres	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
CMS1_k127_1748960_21	1254432.SCE1572_34875	1.07e-05	54.0	COG3215@1|root,COG3215@2|Bacteria	2|Bacteria	NU	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ,cNMP_binding
CMS1_k127_1748960_4	994573.T472_0200040	1.935e-174	556.0	COG1858@1|root,COG1858@2|Bacteria,1V3UY@1239|Firmicutes,24VJJ@186801|Clostridia	186801|Clostridia	C	Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
CMS1_k127_1749747_0	658086.HMPREF0994_03992	1.05e-96	331.0	COG3525@1|root,COG3525@2|Bacteria	2|Bacteria	G	beta-N-acetylhexosaminidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4838,F5_F8_type_C,Glyco_hydro_67N
CMS1_k127_1749747_1	649638.Trad_0622	1.422e-92	312.0	COG0788@1|root,COG0788@2|Bacteria,1WJ8C@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)	purU	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	ACT,Formyl_trans_N
CMS1_k127_1749747_2	1254432.SCE1572_30745	6.88e-45	182.0	COG1409@1|root,COG1409@2|Bacteria,1MV07@1224|Proteobacteria,42NNK@68525|delta/epsilon subdivisions,2WJE7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
CMS1_k127_1749747_4	1116472.MGMO_8c00830	3.226e-09	62.0	COG3592@1|root,COG3592@2|Bacteria,1QJUH@1224|Proteobacteria,1THW0@1236|Gammaproteobacteria,1XFV0@135618|Methylococcales	135618|Methylococcales	S	Divergent 4Fe-4S mono-cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_19
CMS1_k127_1749747_3	263358.VAB18032_10650	6.02e-15	85.0	COG1216@1|root,COG1216@2|Bacteria,2GP1N@201174|Actinobacteria,4DIIV@85008|Micromonosporales	201174|Actinobacteria	S	COG0463 Glycosyltransferases involved in cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_2,Glyco_transf_7C,Glycos_transf_2
CMS1_k127_1750236_3	575540.Isop_0429	6.845e-14	74.0	COG3119@1|root,COG3119@2|Bacteria,2IX69@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS1_k127_1750236_0	926569.ANT_23840	1.473e-111	364.0	COG4422@1|root,COG4422@2|Bacteria,2G7TP@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF5131)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5131
CMS1_k127_1750236_1	240292.Ava_0171	7.878e-40	159.0	2BWMX@1|root,2ZIUW@2|Bacteria,1G304@1117|Cyanobacteria,1HSNA@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1750236_2	1131462.DCF50_p2422	2.454e-18	89.0	COG0451@1|root,COG0451@2|Bacteria,1V04J@1239|Firmicutes,24CFZ@186801|Clostridia	186801|Clostridia	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1755131_7	177439.DP1193	1.251e-34	136.0	2E3B3@1|root,30S3W@2|Bacteria,1PAT1@1224|Proteobacteria,433J0@68525|delta/epsilon subdivisions,2WYFD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of Unknown function (DUF2784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2784
CMS1_k127_1755131_11	251221.35212745	7.271e-17	88.0	COG0110@1|root,COG1045@1|root,COG2203@1|root,COG0110@2|Bacteria,COG1045@2|Bacteria,COG2203@2|Bacteria,1G2PV@1117|Cyanobacteria	1117|Cyanobacteria	E	PFAM Bacterial transferase hexapeptide (three repeats)	-	-	2.3.1.18	ko:K00633	-	-	-	-	ko00000,ko01000	-	-	-	GAF_2,Hexapep,Hexapep_2
CMS1_k127_1755131_9	869210.Marky_0563	2.922e-26	118.0	COG1011@1|root,COG1011@2|Bacteria,1WI88@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
CMS1_k127_1755131_10	309803.CTN_0812	5.859e-21	101.0	COG0639@1|root,COG0639@2|Bacteria,2GC5Q@200918|Thermotogae	200918|Thermotogae	T	Phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
CMS1_k127_1755131_8	945713.IALB_0305	1.418e-30	125.0	COG0776@1|root,COG0776@2|Bacteria	2|Bacteria	L	regulation of translation	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
CMS1_k127_1755131_4	1499967.BAYZ01000103_gene3758	5.187e-90	322.0	COG0457@1|root,COG0457@2|Bacteria	1499967.BAYZ01000103_gene3758|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1755131_1	909663.KI867150_gene213	9.895e-133	445.0	COG0457@1|root,COG0457@2|Bacteria,1NNJ6@1224|Proteobacteria,42PBD@68525|delta/epsilon subdivisions,2WKWJ@28221|Deltaproteobacteria,2MRCI@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
CMS1_k127_1755131_2	204669.Acid345_4042	3.867e-123	404.0	COG0473@1|root,COG0473@2|Bacteria,3Y2VW@57723|Acidobacteria,2JIUD@204432|Acidobacteriia	204432|Acidobacteriia	CE	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.41	ko:K00030	ko00020,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010	R00709	RC00114	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
CMS1_k127_1755131_6	641524.ADICYQ_3145	6.634e-56	203.0	COG3193@1|root,COG3193@2|Bacteria,4NP80@976|Bacteroidetes,47Q4D@768503|Cytophagia	976|Bacteroidetes	S	Haem-degrading	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
CMS1_k127_1755131_5	930169.B5T_03664	3.215e-79	280.0	COG0385@1|root,COG0385@2|Bacteria,1MXF3@1224|Proteobacteria,1RNZF@1236|Gammaproteobacteria,1XHYJ@135619|Oceanospirillales	135619|Oceanospirillales	S	Bile acid sodium symporter	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
CMS1_k127_1755131_0	33876.JNXY01000025_gene5296	8.71e-192	608.0	COG4225@1|root,COG4225@2|Bacteria,2I2TJ@201174|Actinobacteria,4DGGH@85008|Micromonosporales	201174|Actinobacteria	S	Glycosyl Hydrolase Family 88	-	-	3.2.1.180	ko:K18581	-	-	R10867	RC00049,RC02427	ko00000,ko01000	-	GH88	-	Glyco_hydro_88
CMS1_k127_1755131_3	1499967.BAYZ01000075_gene2075	4.067e-102	336.0	COG0673@1|root,COG0673@2|Bacteria,2NQDC@2323|unclassified Bacteria	2|Bacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	MA20_16885	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_1758938_2	278957.ABEA03000004_gene4536	3.149e-17	91.0	COG2165@1|root,COG2165@2|Bacteria,46YQC@74201|Verrucomicrobia,3K9ZW@414999|Opitutae	414999|Opitutae	U	N-terminal cleavage protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
CMS1_k127_1758938_1	1210884.HG799462_gene7973	5.744e-21	109.0	COG1595@1|root,COG1595@2|Bacteria,2IZ6J@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_1758938_0	326427.Cagg_3623	8.194e-89	310.0	COG0443@1|root,COG0443@2|Bacteria,2GBRB@200795|Chloroflexi,3768Q@32061|Chloroflexia	32061|Chloroflexia	O	Hsp70 protein	-	-	-	ko:K04046	-	-	-	-	ko00000,ko03110	1.A.33	-	-	HSP70
CMS1_k127_1758938_3	1397696.KK211189_gene742	1.661e-12	75.0	COG1476@1|root,COG1476@2|Bacteria,1VEGF@1239|Firmicutes,4IPKE@91061|Bacilli	91061|Bacilli	K	Helix-turn-helix domain	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
CMS1_k127_1764088_7	886293.Sinac_4124	0.0001367	48.0	COG0542@1|root,COG0542@2|Bacteria,2IXHI@203682|Planctomycetes	203682|Planctomycetes	O	with chaperone activity ATP-binding	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
CMS1_k127_1764088_5	886293.Sinac_4123	2.463e-29	131.0	COG1695@1|root,COG1695@2|Bacteria,2J00F@203682|Planctomycetes	203682|Planctomycetes	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
CMS1_k127_1764088_1	344747.PM8797T_03239	3.525e-121	401.0	COG3424@1|root,COG3424@2|Bacteria,2IYDA@203682|Planctomycetes	203682|Planctomycetes	Q	Chalcone and stilbene synthases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Chal_sti_synt_C,Chal_sti_synt_N
CMS1_k127_1764088_3	1210884.HG799463_gene10312	3.247e-91	317.0	COG0644@1|root,COG0644@2|Bacteria,2IZDK@203682|Planctomycetes	203682|Planctomycetes	C	FAD binding domain	-	-	1.3.99.38	ko:K21401	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_3
CMS1_k127_1764088_4	344747.PM8797T_03249	5.853e-67	235.0	COG0500@1|root,COG2226@2|Bacteria,2IZZG@203682|Planctomycetes	203682|Planctomycetes	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS1_k127_1764088_0	1122236.KB905141_gene1001	1.292e-303	940.0	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,2VHS3@28216|Betaproteobacteria,2KKSI@206350|Nitrosomonadales	206350|Nitrosomonadales	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
CMS1_k127_1764088_6	765914.ThisiDRAFT_1799	1.061e-06	60.0	COG1335@1|root,COG1335@2|Bacteria,1MV0W@1224|Proteobacteria,1RQJ7@1236|Gammaproteobacteria,1WXHF@135613|Chromatiales	135613|Chromatiales	Q	PFAM isochorismatase hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
CMS1_k127_1764088_2	1445613.JALM01000094_gene3795	1.953e-96	329.0	COG4030@1|root,COG4030@2|Bacteria,2GJFD@201174|Actinobacteria,4EE98@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF2961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
CMS1_k127_176555_2	1288963.ADIS_0133	3.081e-27	114.0	COG0673@1|root,COG0673@2|Bacteria,4NGHJ@976|Bacteroidetes,47NH0@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_176555_4	234267.Acid_0845	5.02e-19	97.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	cpeZ	-	-	ko:K05384,ko:K05386	ko00196,ko01100,map00196,map01100	-	-	-	ko00000,ko00001,ko00194	-	-	-	HEAT_2
CMS1_k127_176555_1	1217720.ALOX01000004_gene4052	4.302e-48	185.0	COG0596@1|root,COG0596@2|Bacteria,1MW2P@1224|Proteobacteria,2TSS3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Alpha beta hydrolase	MA20_32265	-	1.11.1.10	ko:K00433	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1
CMS1_k127_176555_0	1123242.JH636434_gene5111	1.501e-148	483.0	COG2133@1|root,COG2133@2|Bacteria,2IWVG@203682|Planctomycetes	203682|Planctomycetes	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_176555_3	521045.Kole_0690	1.087e-22	111.0	COG3868@1|root,COG3868@2|Bacteria,2GEB7@200918|Thermotogae	200918|Thermotogae	S	PFAM TM1410 hypothetical-related protein	-	-	-	ko:K21006	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	Glyco_hydro_114
CMS1_k127_1775847_0	1236517.BAKO01000041_gene610	3.68e-22	108.0	COG3209@1|root,COG3209@2|Bacteria,4NFUE@976|Bacteroidetes,2FN4E@200643|Bacteroidia	976|Bacteroidetes	M	RHS repeat-associated core domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS,RHS_repeat
CMS1_k127_1775847_1	102129.Lepto7375DRAFT_2212	4.586e-06	58.0	COG3209@1|root,COG3209@2|Bacteria,1G4PY@1117|Cyanobacteria,1H8YZ@1150|Oscillatoriales	1117|Cyanobacteria	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
CMS1_k127_1789836_2	358220.C380_21535	7.593e-21	96.0	COG3119@1|root,COG3119@2|Bacteria,1MUJH@1224|Proteobacteria,2WEXA@28216|Betaproteobacteria,4A9KB@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
CMS1_k127_1789836_1	404589.Anae109_2993	3.056e-128	419.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,42P3Y@68525|delta/epsilon subdivisions,2WJG5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
CMS1_k127_1789836_0	1382359.JIAL01000001_gene135	7.385e-213	679.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,3Y3NX@57723|Acidobacteria,2JKIA@204432|Acidobacteriia	204432|Acidobacteriia	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR,POR_N
CMS1_k127_1789836_3	314230.DSM3645_18271	6.826e-19	98.0	COG2319@1|root,COG2319@2|Bacteria,2IWR9@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PD40,PSCyt1,WD40
CMS1_k127_1804006_1	313628.LNTAR_17398	1.995e-25	111.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS1_k127_1804006_0	1396141.BATP01000060_gene4665	2.263e-134	454.0	COG3345@1|root,COG3345@2|Bacteria,46XJC@74201|Verrucomicrobia,2IW2A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	alpha-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1805069_1	267747.PPA0219	3.506e-09	68.0	COG0673@1|root,COG0673@2|Bacteria,2GKW0@201174|Actinobacteria,4DPXP@85009|Propionibacteriales	201174|Actinobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_1805069_0	237368.SCABRO_01827	4.997e-25	113.0	COG0655@1|root,COG0655@2|Bacteria	2|Bacteria	S	NAD(P)H dehydrogenase (quinone) activity	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_2647	FMN_red
CMS1_k127_1805069_2	1304874.JAFY01000002_gene222	5.519e-07	57.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_4,Phage_integrase
CMS1_k127_1812286_0	573370.DMR_08620	8.097e-111	375.0	COG1075@1|root,COG1075@2|Bacteria,1NYAK@1224|Proteobacteria,42Q3C@68525|delta/epsilon subdivisions,2WMAK@28221|Deltaproteobacteria,2MA00@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
CMS1_k127_1812286_1	1307759.JOMJ01000003_gene970	5.223e-53	202.0	COG4373@1|root,COG4373@2|Bacteria,1R5BY@1224|Proteobacteria,42QK7@68525|delta/epsilon subdivisions,2WKWP@28221|Deltaproteobacteria,2MA1G@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Terminase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_6
CMS1_k127_1814407_2	309799.DICTH_0489	6.332e-08	63.0	arCOG07336@1|root,2Z8ST@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1814407_1	1403819.BATR01000098_gene3283	2.701e-56	211.0	COG3828@1|root,COG3828@2|Bacteria,46TIK@74201|Verrucomicrobia,2IVGD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
CMS1_k127_1814407_0	243231.GSU2816	3.125e-127	434.0	COG2204@1|root,COG4191@1|root,COG5000@1|root,COG2204@2|Bacteria,COG4191@2|Bacteria,COG5000@2|Bacteria,1RCM9@1224|Proteobacteria,42MFW@68525|delta/epsilon subdivisions,2WJSJ@28221|Deltaproteobacteria,43TMC@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
CMS1_k127_1814523_3	1125701.HMPREF1221_01616	8.823e-20	97.0	COG2407@1|root,COG2407@2|Bacteria	2|Bacteria	G	Converts the aldose L-fucose into the corresponding ketose L-fuculose	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1814523_4	1082933.MEA186_31486	3.558e-07	60.0	COG3779@1|root,COG3779@2|Bacteria	2|Bacteria	S	protein conserved in bacteria	yegJ	-	-	-	-	-	-	-	-	-	-	-	DUF2314
CMS1_k127_1814523_2	382464.ABSI01000005_gene1264	4.205e-43	166.0	COG0645@1|root,COG0645@2|Bacteria	2|Bacteria	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33
CMS1_k127_1814523_0	1121289.JHVL01000013_gene1648	1.171e-172	557.0	COG0591@1|root,COG0591@2|Bacteria,1TPVE@1239|Firmicutes,248NQ@186801|Clostridia,36FNJ@31979|Clostridiaceae	186801|Clostridia	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	putP	-	-	ko:K03307,ko:K11928	-	-	-	-	ko00000,ko02000	2.A.21,2.A.21.2	-	-	SSF
CMS1_k127_1814523_1	1358423.N180_15435	3.757e-45	187.0	COG3525@1|root,COG3525@2|Bacteria,4NEQN@976|Bacteroidetes,1IT5W@117747|Sphingobacteriia	976|Bacteroidetes	G	Domain of unknown function (DUF4838)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4838,F5_F8_type_C,Glyco_hydro_67N
CMS1_k127_1814523_5	553220.CAMGR0001_0607	1.66e-05	49.0	COG5266@1|root,COG5266@2|Bacteria,1PVKN@1224|Proteobacteria,42PYV@68525|delta/epsilon subdivisions,2YN74@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Domain of unknown function (DUF4198)	cbiK	-	-	ko:K02009	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18	-	-	DUF4198
CMS1_k127_1814720_0	1089550.ATTH01000001_gene2218	9.096e-53	196.0	COG0204@1|root,COG0204@2|Bacteria	2|Bacteria	I	Acyl-transferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
CMS1_k127_1818681_7	583355.Caka_0066	9.726e-27	118.0	28JYU@1|root,2Z9NZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Cytochrome_C7,Paired_CXXCH_1
CMS1_k127_1818681_3	448385.sce4705	9.462e-112	370.0	COG0437@1|root,COG0437@2|Bacteria,1NBU3@1224|Proteobacteria,42MNU@68525|delta/epsilon subdivisions,2WJRG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	dsrO	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11,Fer4_4
CMS1_k127_1818681_2	583355.Caka_0068	7.087e-123	407.0	COG5557@1|root,COG5557@2|Bacteria	2|Bacteria	C	Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
CMS1_k127_1818681_6	1191523.MROS_1565	3.695e-27	119.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	Cytochrome_C554,DUF11,SLH
CMS1_k127_1818681_5	1379698.RBG1_1C00001G0858	9.431e-89	307.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	petC	-	-	ko:K00413	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C
CMS1_k127_1818681_0	1379698.RBG1_1C00001G0857	4.667e-171	549.0	COG5557@1|root,COG5557@2|Bacteria,2NNNQ@2323|unclassified Bacteria	1379698.RBG1_1C00001G0857|-	C	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1818681_4	1379698.RBG1_1C00001G0856	2.76e-98	325.0	COG0437@1|root,COG0437@2|Bacteria,2NNV6@2323|unclassified Bacteria	2|Bacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7
CMS1_k127_1818681_1	1379698.RBG1_1C00001G0855	1.429e-158	529.0	COG0243@1|root,COG0243@2|Bacteria,2NPRJ@2323|unclassified Bacteria	2|Bacteria	C	Molydopterin dinucleotide binding domain	qrcB	-	1.8.5.5	ko:K08352	ko00920,ko01120,map00920,map01120	-	R10149	RC02823	ko00000,ko00001,ko01000,ko02000	5.A.3.5	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CMS1_k127_1818681_8	338963.Pcar_2550	1.559e-25	113.0	COG3303@1|root,COG3303@2|Bacteria,1QY22@1224|Proteobacteria,43C9D@68525|delta/epsilon subdivisions,2WQ1C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
CMS1_k127_1819908_1	566466.NOR53_517	5.295e-33	130.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Phenol_MetA_deg,Toluene_X
CMS1_k127_1819908_0	247639.MGP2080_07072	7.454e-243	763.0	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,1RRUM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
CMS1_k127_1820933_0	886293.Sinac_5129	1.035e-232	727.0	COG4948@1|root,COG4948@2|Bacteria,2IXK2@203682|Planctomycetes	203682|Planctomycetes	M	Belongs to the mandelate racemase muconate lactonizing enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C
CMS1_k127_1820933_3	498761.HM1_0414	2.397e-76	269.0	COG4637@1|root,COG4637@2|Bacteria,1V0EX@1239|Firmicutes,24B14@186801|Clostridia	186801|Clostridia	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21,AAA_23
CMS1_k127_1820933_4	1196835.A458_06305	7.971e-17	87.0	2E85D@1|root,332IY@2|Bacteria,1NHD1@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1820933_2	1303518.CCALI_02288	8.937e-101	336.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	5.1.3.22	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R03244	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	AP_endonuc_2
CMS1_k127_1820933_1	886293.Sinac_6959	4.009e-183	590.0	COG2010@1|root,COG2010@2|Bacteria,2IXTE@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
CMS1_k127_1821538_3	497964.CfE428DRAFT_2593	3.278e-38	161.0	COG0457@1|root,COG0457@2|Bacteria	497964.CfE428DRAFT_2593|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1821538_2	273068.TTE1717	8.832e-49	187.0	COG2199@1|root,COG3706@2|Bacteria,1UHZ8@1239|Firmicutes,25E7W@186801|Clostridia,42FF0@68295|Thermoanaerobacterales	186801|Clostridia	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
CMS1_k127_1821538_0	1121405.dsmv_2071	6.331e-110	371.0	COG1696@1|root,COG1696@2|Bacteria,1MUXN@1224|Proteobacteria,42MIR@68525|delta/epsilon subdivisions,2WMEK@28221|Deltaproteobacteria,2MJC8@213118|Desulfobacterales	28221|Deltaproteobacteria	M	MBOAT, membrane-bound O-acyltransferase family	algI	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
CMS1_k127_1821538_1	545694.TREPR_0418	2.855e-66	236.0	COG1262@1|root,COG1262@2|Bacteria,2J5Y8@203691|Spirochaetes	203691|Spirochaetes	C	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Flavodoxin_4
CMS1_k127_1821538_4	1499967.BAYZ01000090_gene4945	1.675e-29	131.0	COG0823@1|root,COG1807@1|root,COG0823@2|Bacteria,COG1807@2|Bacteria,2NPHZ@2323|unclassified Bacteria	2|Bacteria	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641,ko:K08676	-	-	-	-	ko00000,ko01000,ko01002,ko02000	2.C.1.2	-	-	PD40,PMT_2,Peptidase_S41,Tricorn_C1
CMS1_k127_1821538_5	1340493.JNIF01000003_gene2626	2.895e-18	91.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_1827612_9	1218173.BALCAV_0207665	9.095e-17	84.0	COG0781@1|root,COG0781@2|Bacteria,1VA9B@1239|Firmicutes,4HKMU@91061|Bacilli,1ZH3P@1386|Bacillus	91061|Bacilli	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
CMS1_k127_1827612_4	1382315.JPOI01000001_gene1982	4.264e-68	234.0	COG0054@1|root,COG0054@2|Bacteria,1V1DA@1239|Firmicutes,4HFRA@91061|Bacilli,1WEXX@129337|Geobacillus	91061|Bacilli	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS08940	DMRL_synthase
CMS1_k127_1827612_0	644282.Deba_2379	1.398e-160	514.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,42N1C@68525|delta/epsilon subdivisions,2WIP5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
CMS1_k127_1827612_5	1120985.AUMI01000015_gene1459	8.749e-56	201.0	COG0307@1|root,COG0307@2|Bacteria,1V1EP@1239|Firmicutes,4H4M4@909932|Negativicutes	909932|Negativicutes	H	riboflavin synthase, alpha	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
CMS1_k127_1827612_1	1121430.JMLG01000008_gene1519	1.36e-117	389.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,248MM@186801|Clostridia,260PG@186807|Peptococcaceae	186801|Clostridia	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
CMS1_k127_1827612_10	1229172.JQFA01000002_gene3040	2.854e-10	70.0	COG5433@1|root,COG5433@2|Bacteria,1G0VN@1117|Cyanobacteria,1H992@1150|Oscillatoriales	1117|Cyanobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
CMS1_k127_1827612_3	204669.Acid345_3213	3.908e-69	243.0	COG0563@1|root,COG0563@2|Bacteria,3Y421@57723|Acidobacteria,2JI14@204432|Acidobacteriia	57723|Acidobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	-	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
CMS1_k127_1827612_8	1245469.S58_52410	3.327e-20	105.0	COG1070@1|root,COG1070@2|Bacteria,1MW4A@1224|Proteobacteria,2TR7P@28211|Alphaproteobacteria,3JRNR@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	FGGY family of carbohydrate kinases, N-terminal domain	xylB	GO:0003674,GO:0003824,GO:0004856,GO:0005975,GO:0005996,GO:0005997,GO:0005998,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046365,GO:0046835,GO:0071704,GO:1901575	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
CMS1_k127_1827612_2	1499967.BAYZ01000123_gene2488	3.175e-109	370.0	COG2160@1|root,COG2160@2|Bacteria	2|Bacteria	G	L-arabinose isomerase activity	-	-	5.3.1.4	ko:K01804	ko00040,ko01100,map00040,map01100	-	R01761	RC00516	ko00000,ko00001,ko01000	-	-	-	Arabinose_Iso_C,Arabinose_Isome,Fucose_iso_C
CMS1_k127_1827612_7	1122917.KB899666_gene3396	1.315e-39	161.0	COG3618@1|root,COG3618@2|Bacteria,1VYAA@1239|Firmicutes	1239|Firmicutes	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1827612_6	1303518.CCALI_01171	1.524e-42	162.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_1831935_1	926550.CLDAP_19490	5.628e-33	149.0	COG1319@1|root,COG2931@1|root,COG3420@1|root,COG1319@2|Bacteria,COG2931@2|Bacteria,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	FAD_binding_5
CMS1_k127_1831935_0	1123277.KB893244_gene5165	4.112e-186	617.0	COG3518@1|root,COG3518@2|Bacteria,4NHGQ@976|Bacteroidetes,47MW9@768503|Cytophagia	976|Bacteroidetes	S	anti-sigma factor antagonist activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_67N
CMS1_k127_1834270_2	398512.JQKC01000029_gene4347	2.525e-212	669.0	COG0499@1|root,COG0499@2|Bacteria,1TQY0@1239|Firmicutes,248S3@186801|Clostridia,3WHN7@541000|Ruminococcaceae	186801|Clostridia	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
CMS1_k127_1834270_10	909663.KI867150_gene2403	2.024e-59	216.0	COG1476@1|root,COG2114@1|root,COG1476@2|Bacteria,COG2114@2|Bacteria,1PFB4@1224|Proteobacteria,439XG@68525|delta/epsilon subdivisions,2WYP5@28221|Deltaproteobacteria,2MSBM@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
CMS1_k127_1834270_6	886293.Sinac_3667	4.187e-87	293.0	COG3880@1|root,COG3880@2|Bacteria,2IYYJ@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
CMS1_k127_1834270_0	1128421.JAGA01000003_gene2870	0.0	1110.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,2NNV6@2323|unclassified Bacteria	2|Bacteria	C	4Fe-4S dicluster domain	hmeA	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molydop_binding
CMS1_k127_1834270_3	1340493.JNIF01000004_gene151	2.075e-194	617.0	COG5557@1|root,COG5557@2|Bacteria,3Y3NS@57723|Acidobacteria	57723|Acidobacteria	C	PFAM Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
CMS1_k127_1834270_9	1128421.JAGA01000003_gene2872	3.217e-63	223.0	COG2010@1|root,COG2010@2|Bacteria,2NPSE@2323|unclassified Bacteria	2|Bacteria	C	Protein of unknown function (DUF3341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
CMS1_k127_1834270_11	204669.Acid345_3000	1.138e-49	185.0	COG2010@1|root,COG2010@2|Bacteria,3Y2MN@57723|Acidobacteria,2JI6T@204432|Acidobacteriia	204432|Acidobacteriia	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CMS1_k127_1834270_5	1128421.JAGA01000003_gene2874	1.539e-99	339.0	COG4531@1|root,COG4531@2|Bacteria,2NP5Y@2323|unclassified Bacteria	2|Bacteria	P	ABC-type Zn2 transport system, periplasmic component surface adhesin	actF	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1834270_12	1121939.L861_00210	1.761e-17	89.0	2EJZ3@1|root,33DPP@2|Bacteria,1NKIC@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1834270_7	234267.Acid_0496	1.25e-73	259.0	COG1999@1|root,COG1999@2|Bacteria,3Y3XH@57723|Acidobacteria	57723|Acidobacteria	S	signal sequence binding	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
CMS1_k127_1834270_4	204669.Acid345_2996	6.642e-107	355.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,3Y2GR@57723|Acidobacteria,2JHRF@204432|Acidobacteriia	204432|Acidobacteriia	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C
CMS1_k127_1834270_1	1521187.JPIM01000034_gene3583	8.251e-262	815.0	COG0843@1|root,COG0843@2|Bacteria,2G5XS@200795|Chloroflexi,3750X@32061|Chloroflexia	32061|Chloroflexia	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
CMS1_k127_1834270_8	204669.Acid345_2994	1.829e-68	239.0	COG1845@1|root,COG1845@2|Bacteria,3Y414@57723|Acidobacteria,2JI50@204432|Acidobacteriia	204432|Acidobacteriia	C	PFAM cytochrome c oxidase subunit III	-	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
CMS1_k127_1834270_13	1267533.KB906741_gene403	8.766e-17	85.0	2DR0H@1|root,339NS@2|Bacteria,3Y59F@57723|Acidobacteria	57723|Acidobacteria	S	TIGRFAM Caa(3)-type oxidase, subunit IV	-	-	1.9.3.1	ko:K02277	ko00190,ko01100,map00190,map01100	M00155	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.4	-	-	COX4_pro
CMS1_k127_1838236_6	293826.Amet_4573	6.098e-55	202.0	COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,2483Q@186801|Clostridia,36DY4@31979|Clostridiaceae	186801|Clostridia	S	Permease	-	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
CMS1_k127_1838236_1	344747.PM8797T_09059	2.587e-177	567.0	COG1621@1|root,COG1621@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 32 family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,HTH_18
CMS1_k127_1838236_0	661478.OP10G_0366	5.497e-194	609.0	COG4030@1|root,COG4030@2|Bacteria	2|Bacteria	M	Protein of unknown function (DUF2961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
CMS1_k127_1838236_3	1123242.JH636434_gene4006	1.889e-124	414.0	COG3119@1|root,COG3119@2|Bacteria,2IX69@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS1_k127_1838236_5	1082931.KKY_1254	8.104e-113	380.0	COG3119@1|root,COG3119@2|Bacteria,1NTUU@1224|Proteobacteria,2UQWA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS1_k127_1838236_8	247490.KSU1_C1333	4.796e-14	83.0	COG4968@1|root,COG4968@2|Bacteria,2J519@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CMS1_k127_1838236_2	886293.Sinac_5955	7.279e-171	576.0	COG1391@1|root,COG1391@2|Bacteria,2IXPE@203682|Planctomycetes	203682|Planctomycetes	H	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	-	-	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
CMS1_k127_1838236_4	886293.Sinac_5350	2.484e-124	409.0	COG1929@1|root,COG1929@2|Bacteria,2IZSZ@203682|Planctomycetes	203682|Planctomycetes	G	Belongs to the glycerate kinase type-1 family	-	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
CMS1_k127_1838586_1	667014.Thein_0619	5.836e-89	302.0	COG0460@1|root,COG0460@2|Bacteria,2GH5Y@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	Homoserine dehydrogenase	-	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
CMS1_k127_1838586_0	118005.AWNK01000005_gene1608	5.309e-148	477.0	COG0498@1|root,COG0498@2|Bacteria	2|Bacteria	E	threonine synthase activity	thrC	GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	iLJ478.TM0546,iSB619.SA_RS06615,iYO844.BSU32250	PALP
CMS1_k127_1838586_4	545695.TREAZ_2314	4.247e-32	134.0	COG0637@1|root,COG0637@2|Bacteria,2J814@203691|Spirochaetes	203691|Spirochaetes	F	TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED	-	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	HAD_2,dCMP_cyt_deam_1
CMS1_k127_1838586_5	768710.DesyoDRAFT_4733	2.071e-20	92.0	COG1476@1|root,COG1476@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
CMS1_k127_1838586_2	450851.PHZ_c2266	2.622e-65	225.0	COG3631@1|root,COG3631@2|Bacteria,1RFJW@1224|Proteobacteria,2U8J7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
CMS1_k127_1838586_3	1218084.BBJK01000124_gene7016	4.988e-37	144.0	COG1309@1|root,COG1309@2|Bacteria,1RAHE@1224|Proteobacteria,2W325@28216|Betaproteobacteria,1K6BY@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS1_k127_1841000_10	595460.RRSWK_00419	1.983e-10	65.0	2DNKX@1|root,32Y1B@2|Bacteria,2J0P2@203682|Planctomycetes	203682|Planctomycetes	S	Glycine zipper	-	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_Omp
CMS1_k127_1841000_3	886293.Sinac_1412	4.544e-64	236.0	COG1355@1|root,COG1355@2|Bacteria,2IZEZ@203682|Planctomycetes	203682|Planctomycetes	S	Memo-like protein	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
CMS1_k127_1841000_0	1123008.KB905706_gene882	5.034e-266	841.0	COG3408@1|root,COG3408@2|Bacteria,4PE41@976|Bacteroidetes,2FW65@200643|Bacteroidia	976|Bacteroidetes	G	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H
CMS1_k127_1841000_11	392500.Swoo_4255	6.054e-07	62.0	28JTM@1|root,2Z9IU@2|Bacteria,1R4C3@1224|Proteobacteria,1S120@1236|Gammaproteobacteria,2QAYM@267890|Shewanellaceae	1236|Gammaproteobacteria	M	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
CMS1_k127_1841000_8	368407.Memar_1907	3.641e-12	78.0	COG3291@1|root,arCOG02540@1|root,arCOG06836@1|root,arCOG02510@2157|Archaea,arCOG02540@2157|Archaea,arCOG06836@2157|Archaea	2157|Archaea	P	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2,Kelch_4,PKD
CMS1_k127_1841000_7	1220534.B655_0740	6.442e-22	109.0	arCOG02499@1|root,arCOG10865@1|root,arCOG02499@2157|Archaea,arCOG10865@2157|Archaea	2157|Archaea	S	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF11,NosD
CMS1_k127_1841000_6	1382304.JNIL01000001_gene2775	4.105e-22	101.0	COG3118@1|root,COG3118@2|Bacteria,1VEPC@1239|Firmicutes,4HNXE@91061|Bacilli,27ABM@186823|Alicyclobacillaceae	91061|Bacilli	O	Protein of unknown function (DUF2847)	ytxJ	-	-	-	-	-	-	-	-	-	-	-	DUF2847
CMS1_k127_1841000_2	756272.Plabr_0401	4.157e-141	464.0	COG0526@1|root,COG3391@1|root,COG0526@2|Bacteria,COG3391@2|Bacteria,2IXWV@203682|Planctomycetes	203682|Planctomycetes	CO	PFAM NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL,Thioredoxin_8
CMS1_k127_1841000_4	224325.AF_1002	2.402e-33	134.0	COG2062@1|root,arCOG01992@2157|Archaea,2Y26Y@28890|Euryarchaeota,24776@183980|Archaeoglobi	183980|Archaeoglobi	T	Histidine phosphatase superfamily (branch 1)	-	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
CMS1_k127_1841000_1	1282876.BAOK01000001_gene3483	2.106e-234	749.0	COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,2TS4D@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	COG2366 Protein related to penicillin acylase	-	-	3.5.1.11,3.5.1.97	ko:K01434,ko:K07116	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
CMS1_k127_1841000_5	926566.Terro_1883	3.619e-27	125.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	2.4.1.83,6.2.1.30	ko:K00721,ko:K01912,ko:K08301	ko00360,ko00510,ko01100,ko01120,ko05111,map00360,map00510,map01100,map01120,map05111	-	R01009,R02539	RC00004,RC00005,RC00014	ko00000,ko00001,ko01000,ko01003,ko03009,ko03019	-	GT2	-	Glycos_transf_2
CMS1_k127_1841000_9	876044.IMCC3088_2341	4.252e-12	78.0	COG0500@1|root,COG2226@2|Bacteria,1R3QX@1224|Proteobacteria,1RYQ8@1236|Gammaproteobacteria,1J5CI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG0500 SAM-dependent methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
CMS1_k127_1842136_1	1499967.BAYZ01000186_gene3977	2.893e-117	382.0	COG1148@1|root,COG1148@2|Bacteria	2|Bacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	hdrA	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_6,Fer4_7,Pyr_redox_2
CMS1_k127_1842136_0	616991.JPOO01000003_gene807	2.385e-124	424.0	COG3292@1|root,COG3292@2|Bacteria,4NF9I@976|Bacteroidetes,1I7BR@117743|Flavobacteriia,23II5@178469|Arenibacter	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
CMS1_k127_1844210_2	2850.Phatr44694	2.749e-73	269.0	2BP9V@1|root,2S1RF@2759|Eukaryota,2XBPA@2836|Bacillariophyta	2836|Bacillariophyta	O	Immune inhibitor A peptidase M6	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M6,SdrD_B
CMS1_k127_1844210_5	1191523.MROS_2342	3.106e-11	76.0	COG3866@1|root,COG3866@2|Bacteria	2|Bacteria	G	Pectate lyase	pel3	-	4.2.2.2	ko:K01728	ko00040,ko02024,map00040,map02024	-	R02361,R06240	RC00049,RC00705	ko00000,ko00001,ko01000	-	-	-	Pectinesterase
CMS1_k127_1844210_0	1123242.JH636435_gene1524	8.484e-113	390.0	COG2936@1|root,COG2936@2|Bacteria,2J2G5@203682|Planctomycetes	203682|Planctomycetes	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
CMS1_k127_1844210_3	234267.Acid_4431	3.05e-71	277.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
CMS1_k127_1844210_4	1122603.ATVI01000005_gene3502	5.608e-36	160.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1T5SE@1236|Gammaproteobacteria,1XDE6@135614|Xanthomonadales	135614|Xanthomonadales	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19
CMS1_k127_1844210_1	1379698.RBG1_1C00001G0607	3.537e-104	385.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2NQNE@2323|unclassified Bacteria	2|Bacteria	T	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,TPR_2,TPR_8
CMS1_k127_1845663_6	471857.Svir_18400	1.666e-09	68.0	COG1020@1|root,COG1020@2|Bacteria,2GISR@201174|Actinobacteria,4DXHP@85010|Pseudonocardiales	201174|Actinobacteria	Q	non-ribosomal peptide synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
CMS1_k127_1845663_0	616991.JPOO01000003_gene1313	1.077e-157	508.0	COG3356@1|root,COG3356@2|Bacteria,4NHGJ@976|Bacteroidetes,1I88B@117743|Flavobacteriia,23GP6@178469|Arenibacter	976|Bacteroidetes	S	PFAM Neutral alkaline nonlysosomal ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1845663_5	1408224.SAMCCGM7_c5228	5.941e-17	86.0	COG3549@1|root,COG3549@2|Bacteria,1MZKX@1224|Proteobacteria,2UBQF@28211|Alphaproteobacteria,4BGQE@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	RelE-like toxin of type II toxin-antitoxin system HigB	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
CMS1_k127_1845663_3	879212.DespoDRAFT_03311	1.992e-45	168.0	COG3093@1|root,COG3093@2|Bacteria,1N76J@1224|Proteobacteria,42T22@68525|delta/epsilon subdivisions,2WPAE@28221|Deltaproteobacteria,2MKSI@213118|Desulfobacterales	28221|Deltaproteobacteria	K	TIGRFAM addiction module antidote protein, HigA family	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
CMS1_k127_1845663_1	1121335.Clst_0831	2.712e-95	321.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,3WGIW@541000|Ruminococcaceae	186801|Clostridia	IQ	reductase	srlD	-	1.1.1.140,1.1.1.304,1.1.1.76	ko:K00068,ko:K03366	ko00051,ko00650,map00051,map00650	-	R02855,R02946,R03707,R05607,R09078,R10505	RC00085,RC00205,RC00525	ko00000,ko00001,ko01000	-	-	-	adh_short,adh_short_C2
CMS1_k127_1845663_2	316274.Haur_1529	1.01e-73	263.0	COG1063@1|root,COG1063@2|Bacteria,2G894@200795|Chloroflexi	200795|Chloroflexi	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N
CMS1_k127_1848093_9	979556.MTES_3148	2.499e-05	52.0	COG1215@1|root,COG1215@2|Bacteria,2GMWF@201174|Actinobacteria,4FKGG@85023|Microbacteriaceae	201174|Actinobacteria	M	Glycosyltransferase like family 2	exoA	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
CMS1_k127_1848093_3	429009.Adeg_0104	1.127e-40	165.0	COG0438@1|root,COG0438@2|Bacteria,1UHSF@1239|Firmicutes,25EAY@186801|Clostridia,42G5D@68295|Thermoanaerobacterales	186801|Clostridia	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS1_k127_1848093_5	945713.IALB_2072	2.071e-27	131.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,FlgD_ig,ILEI,Peptidase_C25,Propeptide_C25
CMS1_k127_1848093_7	1047013.AQSP01000128_gene444	9.592e-18	95.0	2CK1R@1|root,32V4M@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1848093_8	313628.LNTAR_11366	1.386e-13	82.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red,EcsC
CMS1_k127_1848093_2	502025.Hoch_0560	2.728e-81	286.0	COG1453@1|root,COG1453@2|Bacteria,1QZ5K@1224|Proteobacteria,43CG9@68525|delta/epsilon subdivisions,2X7RA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Aldo/keto reductase family	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17
CMS1_k127_1848093_0	502025.Hoch_0561	2.752e-217	687.0	COG0348@1|root,COG1143@1|root,COG1245@1|root,COG0348@2|Bacteria,COG1143@2|Bacteria,COG1245@2|Bacteria,1MY5M@1224|Proteobacteria,43BPV@68525|delta/epsilon subdivisions,2WJVS@28221|Deltaproteobacteria,2YW51@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5,Fer4_7
CMS1_k127_1848093_1	502025.Hoch_0562	2.45e-101	341.0	COG2006@1|root,COG2006@2|Bacteria,1QMGX@1224|Proteobacteria,42PRJ@68525|delta/epsilon subdivisions,2WMFN@28221|Deltaproteobacteria,2Z073@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
CMS1_k127_1848093_4	1123399.AQVE01000023_gene422	2.049e-36	158.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,1RPJS@1236|Gammaproteobacteria,45ZVF@72273|Thiotrichales	72273|Thiotrichales	NU	Type II and III secretion system protein	-	-	-	-	-	-	-	-	-	-	-	-	Secretin,Secretin_N
CMS1_k127_1849548_2	1396141.BATP01000016_gene2844	1.048e-15	84.0	COG0755@1|root,COG0755@2|Bacteria,46VBM@74201|Verrucomicrobia,2IU24@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Cytochrome C assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
CMS1_k127_1849548_0	240016.ABIZ01000001_gene3954	8.737e-74	262.0	COG1333@1|root,COG1333@2|Bacteria,46SUY@74201|Verrucomicrobia,2IUGM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	ResB-like family	-	-	-	-	-	-	-	-	-	-	-	-	ResB
CMS1_k127_1849548_3	1121920.AUAU01000001_gene2237	1.382e-13	83.0	2E533@1|root,32ZW9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1849548_1	240016.ABIZ01000001_gene3955	1.152e-22	111.0	2E533@1|root,32ZW9@2|Bacteria,46X7Y@74201|Verrucomicrobia,2IUXW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1849565_0	452637.Oter_2586	3.056e-32	140.0	2E533@1|root,32ZW9@2|Bacteria,46SZX@74201|Verrucomicrobia,3K856@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1853863_5	1343739.PAP_06505	1.781e-52	189.0	arCOG01797@1|root,arCOG01797@2157|Archaea	2157|Archaea	M	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS1_k127_1853863_0	580340.Tlie_0727	2.584e-255	801.0	COG0441@1|root,COG0441@2|Bacteria,3T9WZ@508458|Synergistetes	508458|Synergistetes	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
CMS1_k127_1853863_6	1293054.HSACCH_01469	5.93e-52	192.0	COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,247SC@186801|Clostridia,3WAJ8@53433|Halanaerobiales	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	yacO	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
CMS1_k127_1853863_3	1144307.PMI04_04186	5.353e-70	246.0	COG0500@1|root,COG2226@2|Bacteria,1MV7N@1224|Proteobacteria,2TYS2@28211|Alphaproteobacteria,2KEVC@204457|Sphingomonadales	204457|Sphingomonadales	H	RNA cap guanine-N2 methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS1_k127_1853863_9	386456.JQKN01000002_gene2773	1.159e-21	107.0	COG0040@1|root,arCOG02208@2157|Archaea,2Y32G@28890|Euryarchaeota,23PBA@183925|Methanobacteria	183925|Methanobacteria	E	PFAM ATP phosphoribosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	HisG
CMS1_k127_1853863_4	338969.Rfer_4110	9.877e-63	226.0	COG2764@1|root,COG2764@2|Bacteria,1N0S4@1224|Proteobacteria,2VTFT@28216|Betaproteobacteria,4AEJ9@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	3-dmu-9_3-mt
CMS1_k127_1853863_2	575540.Isop_1263	4.303e-71	252.0	28ND0@1|root,2ZBFU@2|Bacteria,2J2X6@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1853863_8	517418.Ctha_0781	2.412e-41	161.0	COG4221@1|root,COG4221@2|Bacteria,1FE5R@1090|Chlorobi	1090|Chlorobi	S	short-chain dehydrogenase reductase SDR	-	-	1.1.1.276	ko:K05886	-	-	-	-	ko00000,ko01000	-	-	-	adh_short
CMS1_k127_1853863_1	1288963.ADIS_1567	2.754e-93	317.0	COG0530@1|root,COG0530@2|Bacteria,4NFBC@976|Bacteroidetes,47K1Z@768503|Cytophagia	976|Bacteroidetes	P	Sodium/calcium exchanger protein	yrbG	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
CMS1_k127_1853863_12	1121936.AUHI01000002_gene2574	9.256e-08	58.0	COG1262@1|root,COG1262@2|Bacteria,1TT4R@1239|Firmicutes,4HA8D@91061|Bacilli	91061|Bacilli	S	Sulfatase-modifying factor enzyme 1	pkn1	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase
CMS1_k127_1853863_13	582744.Msip34_1793	7.675e-07	54.0	COG5660@1|root,COG5660@2|Bacteria,1NH4R@1224|Proteobacteria,2W81G@28216|Betaproteobacteria,2KNB0@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
CMS1_k127_1853863_7	1112274.KI911560_gene1583	8.442e-48	178.0	COG1595@1|root,COG1595@2|Bacteria,1RHKM@1224|Proteobacteria,2VRMP@28216|Betaproteobacteria,2KM2U@206350|Nitrosomonadales	206350|Nitrosomonadales	K	RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_1853863_14	344747.PM8797T_20793	3.267e-05	55.0	28ND0@1|root,2ZBFU@2|Bacteria,2J2X6@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1853863_11	1121859.KB890738_gene3356	4.168e-17	86.0	COG2105@1|root,COG2105@2|Bacteria,4NQXV@976|Bacteroidetes	976|Bacteroidetes	S	PFAM AIG2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1859311_29	96561.Dole_0695	1.897e-15	76.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,42MWZ@68525|delta/epsilon subdivisions,2WJ2B@28221|Deltaproteobacteria,2MHTQ@213118|Desulfobacterales	28221|Deltaproteobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
CMS1_k127_1859311_16	269796.Rru_A2689	2.462e-44	166.0	COG0051@1|root,COG0051@2|Bacteria,1RGWF@1224|Proteobacteria,2U95D@28211|Alphaproteobacteria,2JST1@204441|Rhodospirillales	204441|Rhodospirillales	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
CMS1_k127_1859311_7	574087.Acear_0162	5.428e-68	237.0	COG0087@1|root,COG0087@2|Bacteria,1TPFT@1239|Firmicutes,247NH@186801|Clostridia,3WAJF@53433|Halanaerobiales	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
CMS1_k127_1859311_13	1196324.A374_17404	6.512e-51	189.0	COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,4HB01@91061|Bacilli	91061|Bacilli	J	Forms part of the polypeptide exit tunnel	rplD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
CMS1_k127_1859311_28	42256.RradSPS_1941	2.502e-21	98.0	COG0089@1|root,COG0089@2|Bacteria,2IQ7V@201174|Actinobacteria,4CQIU@84995|Rubrobacteria	84995|Rubrobacteria	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
CMS1_k127_1859311_2	648996.Theam_0260	4.594e-119	388.0	COG0090@1|root,COG0090@2|Bacteria,2G3KP@200783|Aquificae	200783|Aquificae	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
CMS1_k127_1859311_19	1121406.JAEX01000006_gene2298	5.022e-41	152.0	COG0185@1|root,COG0185@2|Bacteria,1RGYX@1224|Proteobacteria,42THY@68525|delta/epsilon subdivisions,2WQ0F@28221|Deltaproteobacteria,2MBZW@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
CMS1_k127_1859311_27	1462526.BN990_03786	1.99e-22	103.0	COG0091@1|root,COG0091@2|Bacteria,1V6PU@1239|Firmicutes,4HIK2@91061|Bacilli,4C5PD@84406|Virgibacillus	91061|Bacilli	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
CMS1_k127_1859311_4	243231.GSU2851	1.149e-82	281.0	COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,42N5W@68525|delta/epsilon subdivisions,2WIU3@28221|Deltaproteobacteria,43T5Z@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
CMS1_k127_1859311_9	1120972.AUMH01000017_gene724	2.08e-63	219.0	COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,4HFPN@91061|Bacilli,278B2@186823|Alicyclobacillaceae	91061|Bacilli	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
CMS1_k127_1859311_31	1172185.KB911531_gene3457	1.258e-11	67.0	COG0255@1|root,COG0255@2|Bacteria,2IQ6V@201174|Actinobacteria,4G2ZP@85025|Nocardiaceae	201174|Actinobacteria	J	Belongs to the universal ribosomal protein uL29 family	rpmC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
CMS1_k127_1859311_25	373903.Hore_01260	8.767e-28	115.0	COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,24MSW@186801|Clostridia,3WAVI@53433|Halanaerobiales	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
CMS1_k127_1859311_12	685035.ADAE01000002_gene2640	2.111e-51	188.0	COG0093@1|root,COG0093@2|Bacteria,1RCWZ@1224|Proteobacteria,2U743@28211|Alphaproteobacteria,2K4G3@204457|Sphingomonadales	204457|Sphingomonadales	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
CMS1_k127_1859311_23	760568.Desku_3046	1.247e-32	129.0	COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,24MY0@186801|Clostridia,26260@186807|Peptococcaceae	186801|Clostridia	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
CMS1_k127_1859311_8	555088.DealDRAFT_1511	1.005e-66	232.0	COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,247X0@186801|Clostridia,42JTF@68298|Syntrophomonadaceae	186801|Clostridia	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
CMS1_k127_1859311_26	246194.CHY_2296	3.804e-25	105.0	COG0199@1|root,COG0199@2|Bacteria,1VEF6@1239|Firmicutes,24QR1@186801|Clostridia,42H2Z@68295|Thermoanaerobacterales	186801|Clostridia	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
CMS1_k127_1859311_17	1267534.KB906757_gene807	1.391e-42	163.0	COG0096@1|root,COG0096@2|Bacteria,3Y4IE@57723|Acidobacteria,2JJ74@204432|Acidobacteriia	204432|Acidobacteriia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
CMS1_k127_1859311_10	446468.Ndas_5139	7.125e-62	218.0	COG0097@1|root,COG0097@2|Bacteria,2GK35@201174|Actinobacteria,4EIFJ@85012|Streptosporangiales	201174|Actinobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
CMS1_k127_1859311_24	1340493.JNIF01000003_gene3223	6.662e-32	128.0	COG0256@1|root,COG0256@2|Bacteria,3Y5CH@57723|Acidobacteria	57723|Acidobacteria	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
CMS1_k127_1859311_11	720554.Clocl_3878	1.119e-54	201.0	COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,3WICZ@541000|Ruminococcaceae	186801|Clostridia	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
CMS1_k127_1859311_21	1267580.AF6_0127	1.288e-38	150.0	COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,4HFPW@91061|Bacilli,21WV2@150247|Anoxybacillus	91061|Bacilli	J	Ribosomal protein L15	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
CMS1_k127_1859311_1	289376.THEYE_A1427	1.197e-141	462.0	COG0201@1|root,COG0201@2|Bacteria,3J0C0@40117|Nitrospirae	40117|Nitrospirae	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
CMS1_k127_1859311_6	667014.Thein_1484	8.323e-69	243.0	COG0563@1|root,COG0563@2|Bacteria,2GGXU@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
CMS1_k127_1859311_5	1009370.ALO_03501	4.958e-81	279.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,4H2VZ@909932|Negativicutes	909932|Negativicutes	E	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
CMS1_k127_1859311_22	457570.Nther_0218	2.241e-34	134.0	COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,24MQE@186801|Clostridia	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
CMS1_k127_1859311_30	309799.DICTH_0860	6.459e-13	68.0	COG0257@1|root,COG0257@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
CMS1_k127_1859311_15	697303.Thewi_2230	2.891e-47	173.0	COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,24HCT@186801|Clostridia,42G97@68295|Thermoanaerobacterales	186801|Clostridia	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
CMS1_k127_1859311_14	883081.HMPREF9698_00858	1.074e-48	177.0	COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,4HH2T@91061|Bacilli,27GBS@186828|Carnobacteriaceae	91061|Bacilli	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
CMS1_k127_1859311_3	1201288.M900_2672	1.459e-85	295.0	COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,42MIX@68525|delta/epsilon subdivisions,2MSPW@213481|Bdellovibrionales,2WJ5K@28221|Deltaproteobacteria	213481|Bdellovibrionales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
CMS1_k127_1859311_20	1515746.HR45_17005	1.653e-39	150.0	COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,1S3QK@1236|Gammaproteobacteria,2QBMK@267890|Shewanellaceae	1236|Gammaproteobacteria	J	PFAM ribosomal protein L17	rplQ	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
CMS1_k127_1859311_18	1283283.ATXA01000008_gene3139	1.85e-42	168.0	COG0673@1|root,COG0673@2|Bacteria,2HF65@201174|Actinobacteria,4EW5F@85013|Frankiales	201174|Actinobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	1.1.1.292	ko:K19181	-	-	-	-	ko00000,ko01000	-	-	-	GFO_IDH_MocA
CMS1_k127_1859311_0	1116472.MGMO_111c00270	4.662e-216	678.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,1RMP2@1236|Gammaproteobacteria,1XESA@135618|Methylococcales	135618|Methylococcales	H	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
CMS1_k127_1871765_0	886293.Sinac_2800	1.406e-123	408.0	COG4409@1|root,COG4409@2|Bacteria,2IX8T@203682|Planctomycetes	203682|Planctomycetes	G	BNR repeat-like domain	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2
CMS1_k127_188331_3	339860.Msp_0261	1.855e-10	73.0	COG5427@1|root,arCOG00563@2157|Archaea,2Y3TV@28890|Euryarchaeota,23PKA@183925|Methanobacteria	183925|Methanobacteria	S	membrane protein, required for N-linked glycosylation	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS1_k127_188331_0	378806.STAUR_0531	1.354e-295	930.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,42Z54@68525|delta/epsilon subdivisions,2WUB9@28221|Deltaproteobacteria,2YYC4@29|Myxococcales	28221|Deltaproteobacteria	J	Anticodon-binding domain of tRNA	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
CMS1_k127_188331_1	204669.Acid345_3859	4.987e-44	169.0	COG1994@1|root,COG1994@2|Bacteria,3Y58P@57723|Acidobacteria,2JJUI@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
CMS1_k127_188331_2	1123242.JH636436_gene259	1.261e-22	102.0	COG0776@1|root,COG0776@2|Bacteria,2J01P@203682|Planctomycetes	203682|Planctomycetes	L	Belongs to the bacterial histone-like protein family	-	-	-	ko:K03530,ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
CMS1_k127_1898339_3	1121438.JNJA01000001_gene2065	9.247e-22	96.0	COG0642@1|root,COG2205@2|Bacteria,1MW8M@1224|Proteobacteria,42R77@68525|delta/epsilon subdivisions,2WMVR@28221|Deltaproteobacteria,2MAKU@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Integral membrane sensor signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
CMS1_k127_1898339_4	1121439.dsat_0014	2.271e-16	83.0	COG4226@1|root,COG4226@2|Bacteria,1MZYR@1224|Proteobacteria,42WDN@68525|delta/epsilon subdivisions,2WRW3@28221|Deltaproteobacteria,2MDF7@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	HicB family	-	-	-	-	-	-	-	-	-	-	-	-	HicB
CMS1_k127_1898339_1	43989.cce_5038	3.228e-25	108.0	2CT64@1|root,32SSN@2|Bacteria,1GEBI@1117|Cyanobacteria,3KK64@43988|Cyanothece	1117|Cyanobacteria	S	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
CMS1_k127_1898339_2	1303518.CCALI_00811	1.077e-24	117.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	3.1.1.53	ko:K05970	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_2_N,SASA
CMS1_k127_1898339_5	312153.Pnuc_0258	2.459e-07	63.0	COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,2VHG1@28216|Betaproteobacteria,1K42M@119060|Burkholderiaceae	28216|Betaproteobacteria	MU	type I secretion outer membrane protein, TolC	tolC	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
CMS1_k127_1898339_0	1254432.SCE1572_22505	1.365e-150	492.0	COG0515@1|root,COG0515@2|Bacteria,1P913@1224|Proteobacteria,4377Q@68525|delta/epsilon subdivisions,2X28Z@28221|Deltaproteobacteria,2YUDY@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS1_k127_190054_0	706587.Desti_4666	2.717e-74	261.0	COG1893@1|root,COG1893@2|Bacteria,1P0AW@1224|Proteobacteria,42PK4@68525|delta/epsilon subdivisions,2WM1G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
CMS1_k127_190054_3	697282.Mettu_0288	8.455e-33	133.0	COG1917@1|root,COG1917@2|Bacteria,1NA8I@1224|Proteobacteria,1SU7V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PFAM Cupin 2 conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_190054_4	1454004.AW11_03632	1.81e-11	67.0	COG2331@1|root,COG2331@2|Bacteria,1PVEY@1224|Proteobacteria,2VYJG@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
CMS1_k127_190054_1	247490.KSU1_B0363	2.575e-58	216.0	COG0859@1|root,COG0859@2|Bacteria,2IXD5@203682|Planctomycetes	203682|Planctomycetes	M	PFAM glycosyl transferase family 9	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
CMS1_k127_190092_0	1366050.N234_09805	6.249e-212	691.0	COG1579@1|root,COG1579@2|Bacteria,1NR14@1224|Proteobacteria,2VZ72@28216|Betaproteobacteria,1KF11@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Zn-ribbon protein possibly nucleic acid-binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_190092_1	1366050.N234_09810	5.987e-36	141.0	28H5N@1|root,2Z7I8@2|Bacteria,1RC6E@1224|Proteobacteria,2W05M@28216|Betaproteobacteria,1KENA@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1907487_10	404589.Anae109_3601	2.035e-45	171.0	COG1028@1|root,COG1028@2|Bacteria,1MW9A@1224|Proteobacteria,42ZSX@68525|delta/epsilon subdivisions,2WV17@28221|Deltaproteobacteria,2YZ2N@29|Myxococcales	28221|Deltaproteobacteria	IQ	reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS1_k127_1907487_8	335543.Sfum_1407	1.783e-51	186.0	COG4113@1|root,COG4113@2|Bacteria,1N96B@1224|Proteobacteria,42TZ7@68525|delta/epsilon subdivisions,2WR0Y@28221|Deltaproteobacteria,2MS1K@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
CMS1_k127_1907487_14	298653.Franean1_3066	3.587e-12	68.0	COG3344@1|root,COG3344@2|Bacteria,2GUJS@201174|Actinobacteria	201174|Actinobacteria	L	RNA-directed DNA polymerase (reverse transcriptase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,Intron_maturas2,RVT_1
CMS1_k127_1907487_16	1037409.BJ6T_88720	7.07e-07	55.0	2BU1C@1|root,32PA1@2|Bacteria,1NW65@1224|Proteobacteria,2USC6@28211|Alphaproteobacteria,3K44Q@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1907487_6	448385.sce5510	7.326e-67	235.0	COG0637@1|root,COG0637@2|Bacteria,1PUMZ@1224|Proteobacteria,42UAU@68525|delta/epsilon subdivisions,2WSMG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
CMS1_k127_1907487_2	1121033.AUCF01000001_gene2074	1.002e-137	443.0	COG0005@1|root,COG0005@2|Bacteria,1MUWW@1224|Proteobacteria,2TSN3@28211|Alphaproteobacteria,2JPTI@204441|Rhodospirillales	204441|Rhodospirillales	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates	mtnP	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
CMS1_k127_1907487_9	558152.IQ37_07155	5.666e-46	169.0	COG0537@1|root,COG0537@2|Bacteria,4NXJE@976|Bacteroidetes	976|Bacteroidetes	FG	Scavenger mRNA decapping enzyme C-term binding	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
CMS1_k127_1907487_3	452637.Oter_1926	1.154e-134	451.0	COG1502@1|root,COG1502@2|Bacteria,46TDH@74201|Verrucomicrobia,3K9QJ@414999|Opitutae	414999|Opitutae	I	PFAM phospholipase D Transphosphatidylase	-	-	-	ko:K06132	ko00564,ko01100,map00564,map01100	-	R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
CMS1_k127_1907487_4	1232410.KI421428_gene1188	3.081e-114	374.0	COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,42MNC@68525|delta/epsilon subdivisions,2WIUI@28221|Deltaproteobacteria,43S5G@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
CMS1_k127_1907487_12	484018.BACPLE_01426	1.768e-23	116.0	COG2407@1|root,COG2407@2|Bacteria,4P1BT@976|Bacteroidetes,2FMIE@200643|Bacteroidia,4AKFB@815|Bacteroidaceae	976|Bacteroidetes	G	COG2407 L-fucose isomerase and related	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1907487_13	1268240.ATFI01000011_gene1463	7.981e-23	115.0	COG4354@1|root,COG4354@2|Bacteria,4NFQW@976|Bacteroidetes,2FQ1M@200643|Bacteroidia,4APXF@815|Bacteroidaceae	976|Bacteroidetes	G	Pfam:GBA2_N	-	-	3.2.1.45	ko:K17108	ko00511,ko00600,ko01100,map00511,map00600,map01100	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH116	-	DUF608,Glyco_hydr_116N
CMS1_k127_1907487_1	1047013.AQSP01000120_gene937	1.167e-155	499.0	COG4030@1|root,COG4030@2|Bacteria	2|Bacteria	M	Protein of unknown function (DUF2961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
CMS1_k127_1907487_7	690850.Desaf_0489	3.468e-53	201.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,42N2V@68525|delta/epsilon subdivisions,2WIPS@28221|Deltaproteobacteria,2M7XX@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	HflC and HflK could regulate a protease	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
CMS1_k127_1907487_5	363253.LI0675	2.271e-67	243.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,42NUT@68525|delta/epsilon subdivisions,2WKQX@28221|Deltaproteobacteria,2M80N@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
CMS1_k127_1907487_0	1121904.ARBP01000021_gene3579	1.461e-162	532.0	COG3119@1|root,COG3119@2|Bacteria,4NHH7@976|Bacteroidetes,47JYR@768503|Cytophagia	976|Bacteroidetes	P	PFAM sulfatase	mdsA	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CMS1_k127_1907487_11	1303518.CCALI_00634	1.577e-30	125.0	28K2K@1|root,2Z9RX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1920890_13	1122612.AUBA01000018_gene2684	8.363e-43	159.0	COG3385@1|root,COG3385@2|Bacteria,1QURV@1224|Proteobacteria,2TW56@28211|Alphaproteobacteria,2KEB3@204457|Sphingomonadales	204457|Sphingomonadales	L	Transposase DDE domain group 1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
CMS1_k127_1920890_3	331869.BAL199_13955	2.377e-146	471.0	COG3385@1|root,COG3385@2|Bacteria,1QURV@1224|Proteobacteria,2TW56@28211|Alphaproteobacteria,4BSI7@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	L	COG2183 Transcriptional accessory protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
CMS1_k127_1920890_9	869213.JCM21142_93471	5.244e-64	232.0	COG1609@1|root,COG1609@2|Bacteria	2|Bacteria	K	purine nucleotide biosynthetic process	-	-	-	ko:K03406,ko:K10439,ko:K10910	ko02010,ko02020,ko02024,ko02030,ko05111,map02010,map02020,map02024,map02030,map05111	M00212	-	-	ko00000,ko00001,ko00002,ko02000,ko02035	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
CMS1_k127_1920890_8	868595.Desca_0350	1.465e-68	244.0	COG3640@1|root,COG3640@2|Bacteria,1TPCY@1239|Firmicutes,247JM@186801|Clostridia,260Q5@186807|Peptococcaceae	186801|Clostridia	D	PFAM CobQ CobB MinD ParA nucleotide binding domain	cooC	-	-	ko:K07321	-	-	-	-	ko00000	-	-	-	CbiA
CMS1_k127_1920890_6	706587.Desti_0312	7.059e-83	287.0	COG0620@1|root,COG0620@2|Bacteria,1R6KI@1224|Proteobacteria,42PCN@68525|delta/epsilon subdivisions,2WKT3@28221|Deltaproteobacteria,2MRRP@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1920890_11	1191523.MROS_2095	3.246e-61	222.0	COG0646@1|root,COG0646@2|Bacteria	2|Bacteria	E	methionine synthase	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	S-methyl_trans
CMS1_k127_1920890_12	555079.Toce_0809	1.583e-54	202.0	COG3640@1|root,COG3640@2|Bacteria,1UZHR@1239|Firmicutes,24BYR@186801|Clostridia,42FDR@68295|Thermoanaerobacterales	186801|Clostridia	D	AAA domain	cooC1	-	-	ko:K07321	-	-	-	-	ko00000	-	-	-	AAA_31,CbiA
CMS1_k127_1920890_1	909663.KI867150_gene97	4.937e-206	662.0	COG0369@1|root,COG1151@2|Bacteria,1NYH2@1224|Proteobacteria,42NE1@68525|delta/epsilon subdivisions,2WIVX@28221|Deltaproteobacteria,2MQ8Q@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit	-	-	1.2.7.4	ko:K00198	ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200	M00377	R07157,R08034	RC00250,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Prismane
CMS1_k127_1920890_0	555779.Dthio_PD3239	1.031e-297	957.0	COG1614@1|root,COG1614@2|Bacteria,1MVI5@1224|Proteobacteria,42N9A@68525|delta/epsilon subdivisions,2WK4H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit	-	-	2.3.1.169	ko:K14138	ko00720,ko01120,ko01200,map00720,map01120,map01200	M00377	R08433,R10243	RC00004,RC00113,RC01144,RC02963,RC02964,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhC
CMS1_k127_1920890_5	1009370.ALO_06353	1.175e-83	315.0	COG2069@1|root,COG2069@2|Bacteria,1TSSY@1239|Firmicutes,4H6FX@909932|Negativicutes	909932|Negativicutes	C	CO dehydrogenase/acetyl-CoA synthase delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	CdhD
CMS1_k127_1920890_4	933262.AXAM01000033_gene1647	2.744e-121	403.0	COG1456@1|root,COG1456@2|Bacteria,1R4RE@1224|Proteobacteria,42M89@68525|delta/epsilon subdivisions,2WJVQ@28221|Deltaproteobacteria,2MI7W@213118|Desulfobacterales	28221|Deltaproteobacteria	C	CO dehydrogenase acetyl-CoA synthase delta subunit	-	-	2.1.1.245	ko:K00197	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00357,M00377,M00422	R09096,R10219,R10243	RC00004,RC00113,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhD,FeS
CMS1_k127_1920890_2	246194.CHY_1224	2.538e-153	506.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,1TP0H@1239|Firmicutes,247S0@186801|Clostridia,42F3G@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
CMS1_k127_1920890_10	439235.Dalk_2340	6.11e-63	224.0	COG1418@1|root,COG1418@2|Bacteria,1R60M@1224|Proteobacteria,42NFJ@68525|delta/epsilon subdivisions,2WIJT@28221|Deltaproteobacteria,2MJ3J@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM metal-dependent phosphohydrolase HD sub	-	-	-	-	-	-	-	-	-	-	-	-	HD
CMS1_k127_1920890_14	1540257.JQMW01000011_gene1818	6.376e-17	89.0	2C5Z2@1|root,32A20@2|Bacteria,1V5CS@1239|Firmicutes,24M7C@186801|Clostridia,36H6C@31979|Clostridiaceae	186801|Clostridia	S	Domain of unknown function (DUF3786)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3786
CMS1_k127_1920890_7	1192034.CAP_3819	8.399e-69	252.0	COG2271@1|root,COG2271@2|Bacteria,1MX4V@1224|Proteobacteria,42QEQ@68525|delta/epsilon subdivisions,2WQEB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Major Facilitator Superfamily	-	-	-	ko:K02445,ko:K07783	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.1.4.3,2.A.1.4.4,2.A.1.4.6	-	-	MFS_1
CMS1_k127_1920890_15	1499967.BAYZ01000171_gene5584	9.551e-13	72.0	COG0407@1|root,COG0407@2|Bacteria,2NRD5@2323|unclassified Bacteria	2|Bacteria	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
CMS1_k127_1922086_6	760192.Halhy_0308	5.238e-05	57.0	COG1452@1|root,COG1452@2|Bacteria,4NFWD@976|Bacteroidetes,1IQE0@117747|Sphingobacteriia	976|Bacteroidetes	M	Organic solvent tolerance protein OstA	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1922086_7	59374.Fisuc_2525	0.000625	53.0	COG1452@1|root,COG1452@2|Bacteria	2|Bacteria	M	lipopolysaccharide transport	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1922086_1	266117.Rxyl_0180	1.669e-91	316.0	COG1473@1|root,COG1473@2|Bacteria,2GK05@201174|Actinobacteria,4CQ6J@84995|Rubrobacteria	84995|Rubrobacteria	S	Peptidase family M20/M25/M40	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
CMS1_k127_1922086_5	1341151.ASZU01000003_gene2555	3.594e-13	73.0	COG3071@1|root,COG3071@2|Bacteria,1UHZ2@1239|Firmicutes,4ITCU@91061|Bacilli,27CA5@186824|Thermoactinomycetaceae	91061|Bacilli	H	Protein of unknown function (DUF2905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2905
CMS1_k127_1922086_4	313590.MED134_05974	3.751e-17	89.0	COG0110@1|root,COG0110@2|Bacteria,4PISF@976|Bacteroidetes,1IG5D@117743|Flavobacteriia,37FTR@326319|Dokdonia	976|Bacteroidetes	H	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
CMS1_k127_1922086_0	344747.PM8797T_20688	3.887e-165	538.0	2EXMI@1|root,33QXD@2|Bacteria,2J1TH@203682|Planctomycetes	203682|Planctomycetes	S	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
CMS1_k127_1922086_3	370438.PTH_1110	1.773e-26	123.0	COG1388@1|root,COG1388@2|Bacteria,1VJ2T@1239|Firmicutes,24YEF@186801|Clostridia,264FH@186807|Peptococcaceae	186801|Clostridia	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1922086_2	309807.SRU_1831	7.059e-52	197.0	COG2267@1|root,COG2267@2|Bacteria,4PJWZ@976|Bacteroidetes,1FK2W@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
CMS1_k127_1923448_4	530564.Psta_3178	2.309e-21	96.0	COG2010@1|root,COG2010@2|Bacteria,2IXTE@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
CMS1_k127_1923448_0	530564.Psta_3179	5.296e-212	667.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CMS1_k127_1923448_3	309807.SRU_0642	1.805e-26	111.0	COG1669@1|root,COG1669@2|Bacteria,4PF8C@976|Bacteroidetes,1FKA7@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	Nucleotidyltransferase domain	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
CMS1_k127_1923448_2	1128427.KB904821_gene860	1.044e-27	117.0	COG2361@1|root,COG2361@2|Bacteria,1G7TP@1117|Cyanobacteria,1HCDT@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
CMS1_k127_1923448_1	1162668.LFE_0472	4.813e-73	265.0	COG0303@1|root,COG0303@2|Bacteria,3J0MX@40117|Nitrospirae	40117|Nitrospirae	H	Probable molybdopterin binding domain	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
CMS1_k127_1927049_3	1125863.JAFN01000001_gene2788	2.052e-64	230.0	COG0348@1|root,COG3350@1|root,COG0348@2|Bacteria,COG3350@2|Bacteria,1R9MN@1224|Proteobacteria,42QKX@68525|delta/epsilon subdivisions,2WMMH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	CT	Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_5,Sigma54_activat,cNMP_binding
CMS1_k127_1927049_5	1125863.JAFN01000001_gene2789	8.398e-39	153.0	COG0348@1|root,COG0348@2|Bacteria,1MWR5@1224|Proteobacteria,42NMJ@68525|delta/epsilon subdivisions,2WR5M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	-	ko:K02574	-	-	-	-	ko00000	-	-	-	Fer4_5
CMS1_k127_1927049_2	1125863.JAFN01000001_gene2789	1.238e-65	240.0	COG0348@1|root,COG0348@2|Bacteria,1MWR5@1224|Proteobacteria,42NMJ@68525|delta/epsilon subdivisions,2WR5M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	-	ko:K02574	-	-	-	-	ko00000	-	-	-	Fer4_5
CMS1_k127_1927049_6	1280706.AUJE01000001_gene1953	3.273e-32	139.0	COG1149@1|root,COG1149@2|Bacteria,1V8S0@1239|Firmicutes,4H4ZV@909932|Negativicutes	909932|Negativicutes	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_4,Fer4_6
CMS1_k127_1927049_4	1125863.JAFN01000001_gene2791	1.625e-60	218.0	COG0437@1|root,COG0437@2|Bacteria,1N9WY@1224|Proteobacteria,42MXM@68525|delta/epsilon subdivisions,2WRYW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	-	ko:K02573	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_4,Fer4_7
CMS1_k127_1927049_0	1125863.JAFN01000001_gene2792	0.0	1346.0	COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,42M9Q@68525|delta/epsilon subdivisions,2WKKT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	napA	-	-	ko:K02567	ko00910,ko01120,map00910,map01120	M00529,M00530	R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
CMS1_k127_1927049_1	1125863.JAFN01000001_gene2793	1.241e-233	752.0	COG2010@1|root,COG3258@1|root,COG2010@2|Bacteria,COG3258@2|Bacteria,1RJJ2@1224|Proteobacteria,42SCM@68525|delta/epsilon subdivisions,2WPS4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Cytochrome c	pcmF	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
CMS1_k127_1928603_0	1183438.GKIL_2286	5.698e-60	216.0	COG3191@1|root,COG3191@2|Bacteria	2|Bacteria	EQ	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_5
CMS1_k127_1928603_1	634500.EbC_08910	6.125e-16	83.0	COG4977@1|root,COG4977@2|Bacteria,1MVS8@1224|Proteobacteria,1RQ3Y@1236|Gammaproteobacteria,3X50X@551|Erwinia	1236|Gammaproteobacteria	K	Arabinose operon regulatory protein	mmsR	-	-	ko:K02099	-	-	-	-	ko00000,ko03000	-	-	-	AraC_binding,HTH_18,HTH_AraC
CMS1_k127_1928603_2	234267.Acid_4150	7.426e-14	77.0	COG0607@1|root,32YCZ@2|Bacteria,3Y5Z1@57723|Acidobacteria	57723|Acidobacteria	P	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
CMS1_k127_1933467_1	649638.Trad_2493	4.231e-38	157.0	COG1215@1|root,COG1215@2|Bacteria,1WIG8@1297|Deinococcus-Thermus	2|Bacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
CMS1_k127_1933467_0	1142394.PSMK_04700	6.29e-55	197.0	COG0464@1|root,COG0464@2|Bacteria	2|Bacteria	O	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA,BCS1_N
CMS1_k127_1934196_2	867845.KI911784_gene3577	7.562e-23	106.0	COG1595@1|root,COG1595@2|Bacteria,2G6UE@200795|Chloroflexi,377BU@32061|Chloroflexia	32061|Chloroflexia	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS1_k127_1934196_0	530564.Psta_2300	2.122e-79	280.0	COG0673@1|root,COG0673@2|Bacteria,2IX0C@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_1934196_3	1191523.MROS_1183	1.775e-21	107.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	msrA	-	1.1.98.6,1.8.1.9,1.8.4.11,1.8.4.12	ko:K00384,ko:K12057,ko:K12267,ko:K21636	ko00230,ko00240,ko00450,ko01100,map00230,map00240,map00450,map01100	M00053	R02016,R03596,R09372,R11633,R11634,R11635,R11636	RC00013,RC00613,RC02518,RC02873	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.7.11.1	-	-	AhpC-TSA,PMSR,Pyr_redox_2,SelR,Thioredoxin,Thioredoxin_3,Thioredoxin_7,TraF
CMS1_k127_1934196_1	880070.Cycma_0385	2.104e-54	199.0	COG2407@1|root,COG2407@2|Bacteria,4NGB6@976|Bacteroidetes,47TSI@768503|Cytophagia	976|Bacteroidetes	G	Pfam L-fucose isomerase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Fucose_iso_C
CMS1_k127_1934617_3	927658.AJUM01000034_gene438	3.882e-40	154.0	COG0673@1|root,COG0673@2|Bacteria,4NF96@976|Bacteroidetes,2FNTD@200643|Bacteroidia,3XJC1@558415|Marinilabiliaceae	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_1934617_1	177437.HRM2_15490	4.046e-122	402.0	COG0588@1|root,COG0588@2|Bacteria,1MUVE@1224|Proteobacteria,42PJM@68525|delta/epsilon subdivisions,2WKJN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily	gpmA	GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
CMS1_k127_1934617_0	1303518.CCALI_00158	3.13e-259	810.0	COG0166@1|root,COG0166@2|Bacteria	2|Bacteria	G	Belongs to the GPI family	pgi	GO:0003674,GO:0003824,GO:0004347,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033554,GO:0034404,GO:0034599,GO:0034641,GO:0034654,GO:0034655,GO:0042221,GO:0042802,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0055086,GO:0070887,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iEcSMS35_1347.EcSMS35_4486	PGI
CMS1_k127_1934617_4	96561.Dole_0403	1.477e-06	56.0	2DN2Z@1|root,32V89@2|Bacteria,1N3VG@1224|Proteobacteria,42TI7@68525|delta/epsilon subdivisions,2WQNX@28221|Deltaproteobacteria,2MKM9@213118|Desulfobacterales	28221|Deltaproteobacteria	S	zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-ribbon_3
CMS1_k127_1934617_2	1123508.JH636445_gene6873	1.378e-111	369.0	COG2017@1|root,COG2017@2|Bacteria,2IWRW@203682|Planctomycetes	203682|Planctomycetes	G	Converts alpha-aldose to the beta-anomer	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
CMS1_k127_1945789_2	1144275.COCOR_06031	8.488e-23	103.0	COG3536@1|root,COG3536@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF971)	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	DUF971
CMS1_k127_1945789_1	1121422.AUMW01000024_gene240	1.45e-38	152.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,262RV@186807|Peptococcaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	algU	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_1945789_0	1487953.JMKF01000028_gene1341	3.196e-109	363.0	COG0598@1|root,COG0598@2|Bacteria,1G1AG@1117|Cyanobacteria,1H99G@1150|Oscillatoriales	1117|Cyanobacteria	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
CMS1_k127_1950181_1	1121011.AUCB01000034_gene918	5.922e-12	70.0	COG0730@1|root,COG0730@2|Bacteria,4NIJ9@976|Bacteroidetes,1I0SR@117743|Flavobacteriia,23HU7@178469|Arenibacter	976|Bacteroidetes	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
CMS1_k127_1950181_0	96561.Dole_2882	7.297e-200	629.0	COG0798@1|root,COG0798@2|Bacteria,1MUXY@1224|Proteobacteria,42M0Z@68525|delta/epsilon subdivisions,2WK36@28221|Deltaproteobacteria,2MJ5F@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM Bile acid sodium symporter	arsB	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
CMS1_k127_1955635_0	234267.Acid_3837	5.366e-33	145.0	COG3485@1|root,COG4932@1|root,COG3485@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K14194	ko05150,map05150	-	-	-	ko00000,ko00001	-	-	-	CarboxypepD_reg,DUF11,Gram_pos_anchor,SdrD_B
CMS1_k127_1955635_2	448385.sce1844	2.586e-08	66.0	COG4932@1|root,COG4932@2|Bacteria,1Q2N2@1224|Proteobacteria,4388V@68525|delta/epsilon subdivisions,2X3IH@28221|Deltaproteobacteria,2YW8A@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,PDZ_2
CMS1_k127_1956502_1	1121920.AUAU01000005_gene1047	0.0001516	48.0	COG2835@1|root,COG2835@2|Bacteria	2|Bacteria	EG	tetraacyldisaccharide 4'-kinase activity	ycaR	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	2.7.1.130	ko:K00912,ko:K09791	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Trm112p
CMS1_k127_1956502_0	1150626.PHAMO_570049	5.693e-105	345.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2TSCY@28211|Alphaproteobacteria,2JQXF@204441|Rhodospirillales	204441|Rhodospirillales	E	COG0367 Asparagine synthase (glutamine-hydrolyzing)	-	-	-	-	-	-	-	-	-	-	-	-	Asn_synthase,GATase_7
CMS1_k127_1965515_3	1120792.JAFV01000001_gene84	1.386e-25	114.0	COG0483@1|root,COG0483@2|Bacteria,1MV4W@1224|Proteobacteria,2TV4R@28211|Alphaproteobacteria,36YDW@31993|Methylocystaceae	28211|Alphaproteobacteria	G	Inositol monophosphatase family	suhB2	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
CMS1_k127_1965515_0	861299.J421_4062	8.5e-42	173.0	COG0515@1|root,COG0515@2|Bacteria,1ZU8W@142182|Gemmatimonadetes	142182|Gemmatimonadetes	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS1_k127_1965515_2	1122182.KB903834_gene5718	9.057e-30	136.0	COG0515@1|root,COG0515@2|Bacteria,2GMPZ@201174|Actinobacteria,4D8PV@85008|Micromonosporales	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS1_k127_1965515_1	396588.Tgr7_3139	3.028e-33	140.0	COG5295@1|root,COG5295@2|Bacteria,1N8QZ@1224|Proteobacteria	1224|Proteobacteria	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1965515_5	1089550.ATTH01000001_gene802	9.45e-13	70.0	COG4974@1|root,COG4974@2|Bacteria,4PJBF@976|Bacteroidetes,1FKA1@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
CMS1_k127_1965515_4	1122931.AUAE01000007_gene1131	7.406e-16	90.0	COG3525@1|root,COG3525@2|Bacteria,4NEQN@976|Bacteroidetes,2FMUE@200643|Bacteroidia,230PE@171551|Porphyromonadaceae	976|Bacteroidetes	G	Domain of unknown function (DUF4838)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4838,F5_F8_type_C,Glyco_hydro_20b,Glyco_hydro_67N
CMS1_k127_1971642_9	1480694.DC28_14985	1.969e-34	140.0	COG1285@1|root,COG1285@2|Bacteria,2J7US@203691|Spirochaetes	203691|Spirochaetes	S	MgtC SapB transporter	mgtC	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
CMS1_k127_1971642_11	404589.Anae109_1840	5.608e-26	126.0	COG0457@1|root,COG0457@2|Bacteria,1NFQW@1224|Proteobacteria,42MT2@68525|delta/epsilon subdivisions,2WKWA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_4,TPR_8
CMS1_k127_1971642_0	1304888.ATWF01000001_gene2370	9.22e-298	948.0	COG0841@1|root,COG0841@2|Bacteria,2GESU@200930|Deferribacteres	200930|Deferribacteres	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
CMS1_k127_1971642_3	1121406.JAEX01000006_gene2184	1.544e-58	216.0	COG0845@1|root,COG0845@2|Bacteria,1MW65@1224|Proteobacteria,42QZT@68525|delta/epsilon subdivisions,2WK41@28221|Deltaproteobacteria,2M9V3@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005,ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
CMS1_k127_1971642_7	530564.Psta_0781	3.02e-35	143.0	COG1309@1|root,COG1309@2|Bacteria,2J1M7@203682|Planctomycetes	203682|Planctomycetes	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS1_k127_1971642_1	1125863.JAFN01000001_gene3028	4.612e-271	859.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,42M70@68525|delta/epsilon subdivisions,2WJA8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
CMS1_k127_1971642_10	748449.Halha_2063	2.969e-32	130.0	COG0816@1|root,COG0816@2|Bacteria,1V6ER@1239|Firmicutes,24JGP@186801|Clostridia,3WASR@53433|Halanaerobiales	186801|Clostridia	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	yrrK	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
CMS1_k127_1971642_5	330214.NIDE1709	8.162e-55	209.0	COG1559@1|root,COG1559@2|Bacteria,3J0IR@40117|Nitrospirae	40117|Nitrospirae	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
CMS1_k127_1971642_8	984262.SGRA_0583	7.478e-35	143.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS1_k127_1971642_12	575540.Isop_0359	2.368e-24	118.0	28MEZ@1|root,2ZASI@2|Bacteria,2IYHZ@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1971642_4	880072.Desac_0503	1.086e-57	210.0	COG0235@1|root,COG0235@2|Bacteria,1MW7B@1224|Proteobacteria,42MF3@68525|delta/epsilon subdivisions,2WJXS@28221|Deltaproteobacteria,2MQR6@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	Class II aldolase adducin family protein	-	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
CMS1_k127_1971642_15	138119.DSY0412	3.057e-08	58.0	COG4576@1|root,COG4576@2|Bacteria,1VEI4@1239|Firmicutes,24QJA@186801|Clostridia,26301@186807|Peptococcaceae	186801|Clostridia	CQ	protein EutN carboxysome	-	-	-	ko:K04028	-	-	-	-	ko00000	-	-	-	EutN_CcmL
CMS1_k127_1971642_6	1121472.AQWN01000001_gene63	2.318e-42	163.0	COG4577@1|root,COG4577@2|Bacteria,1UKDS@1239|Firmicutes,24IS5@186801|Clostridia,261TI@186807|Peptococcaceae	186801|Clostridia	CQ	Carbon dioxide concentrating mechanism carboxysome shell protein	csoS1C	-	-	-	-	-	-	-	-	-	-	-	BMC
CMS1_k127_1971642_2	215803.DB30_1144	6.805e-149	485.0	COG1012@1|root,COG1012@2|Bacteria,1QUBI@1224|Proteobacteria,42P3A@68525|delta/epsilon subdivisions,2WIJU@28221|Deltaproteobacteria,2YYR4@29|Myxococcales	28221|Deltaproteobacteria	C	Aldehyde dehydrogenase family	-	-	-	ko:K04021	ko00620,ko01100,ko01120,map00620,map01100,map01120	-	R00228	RC00004,RC01195	ko00000,ko00001	-	-	-	Aldedh
CMS1_k127_1971642_14	1120948.KB903229_gene5271	1.707e-08	65.0	COG1266@1|root,COG1266@2|Bacteria,2HZR1@201174|Actinobacteria,4EDD8@85010|Pseudonocardiales	2|Bacteria	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
CMS1_k127_1971642_13	1203605.HMPREF1531_00752	1.76e-21	96.0	COG4576@1|root,COG4576@2|Bacteria,2GT97@201174|Actinobacteria,4DVTC@85009|Propionibacteriales	201174|Actinobacteria	CQ	Ethanolamine utilisation protein EutN/carboxysome	-	-	-	ko:K04028	-	-	-	-	ko00000	-	-	-	EutN_CcmL
CMS1_k127_1971922_3	101510.RHA1_ro04553	2.646e-10	67.0	COG1082@1|root,COG1082@2|Bacteria,2H1AC@201174|Actinobacteria,4G5CX@85025|Nocardiaceae	201174|Actinobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS1_k127_1971922_0	1123277.KB893172_gene474	7.448e-104	357.0	COG5434@1|root,COG5434@2|Bacteria,4NFSC@976|Bacteroidetes,47Q1K@768503|Cytophagia	976|Bacteroidetes	M	Pectate lyase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_28,Pectate_lyase_3
CMS1_k127_1971922_2	1122138.AQUZ01000005_gene2748	1.059e-12	76.0	COG0702@1|root,COG0702@2|Bacteria,2HVU1@201174|Actinobacteria,4DTYQ@85009|Propionibacteriales	201174|Actinobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
CMS1_k127_1971922_1	1123242.JH636434_gene5272	6.005e-36	154.0	COG1621@1|root,COG1621@2|Bacteria,2IY26@203682|Planctomycetes	2|Bacteria	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Dockerin_1,HTH_18,RicinB_lectin_2
CMS1_k127_1972838_11	1291050.JAGE01000001_gene150	4.346e-13	71.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS1_k127_1972838_13	981384.AEYW01000014_gene74	2.494e-05	55.0	COG1269@1|root,COG1269@2|Bacteria,1MXZG@1224|Proteobacteria,2TUKE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	transmembrane protein EpsH	-	-	-	-	-	-	-	-	-	-	-	-	DUF3485,Exosortase_EpsH
CMS1_k127_1972838_7	1121918.ARWE01000001_gene1794	1.006e-34	145.0	COG1269@1|root,COG1269@2|Bacteria,1MXZG@1224|Proteobacteria,42R3N@68525|delta/epsilon subdivisions,2WMY8@28221|Deltaproteobacteria,43U07@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Transmembrane exosortase (Exosortase_EpsH)	epsH	-	-	-	-	-	-	-	-	-	-	-	DUF3485,Exosortase_EpsH
CMS1_k127_1972838_12	440512.C211_01827	2.873e-06	61.0	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,1RQIX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
CMS1_k127_1972838_9	43989.cce_2351	4.126e-29	125.0	2BVGP@1|root,32QVG@2|Bacteria,1GGUG@1117|Cyanobacteria,3KI5P@43988|Cyanothece	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1972838_8	1183438.GKIL_1604	7.914e-31	141.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1G0TN@1117|Cyanobacteria	1117|Cyanobacteria	D	CobQ CobB MinD ParA nucleotide binding domain	epsB	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA,GNVR,Wzz
CMS1_k127_1972838_1	583355.Caka_0474	3.242e-114	382.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_1972838_5	497964.CfE428DRAFT_1593	1.277e-76	266.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,LRR_5
CMS1_k127_1972838_10	927677.ALVU02000006_gene464	1.707e-18	87.0	COG3209@1|root,COG3209@2|Bacteria,1GB8C@1117|Cyanobacteria	1117|Cyanobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1972838_6	344747.PM8797T_11551	1.689e-61	241.0	COG1413@1|root,COG1413@2|Bacteria,2IZE1@203682|Planctomycetes	203682|Planctomycetes	C	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
CMS1_k127_1972838_2	344747.PM8797T_11556	5.556e-108	367.0	COG0673@1|root,COG0673@2|Bacteria,2IXA3@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_1972838_0	469383.Cwoe_0480	3.157e-183	601.0	COG3525@1|root,COG3525@2|Bacteria,2GYID@201174|Actinobacteria	201174|Actinobacteria	G	Domain of unknown function (DUF4838)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4838,Glyco_hydro_67N
CMS1_k127_1972838_4	96561.Dole_1249	2.935e-79	274.0	COG0300@1|root,COG0300@2|Bacteria,1RG9T@1224|Proteobacteria,43BR5@68525|delta/epsilon subdivisions,2X722@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS1_k127_1972838_3	926550.CLDAP_19490	9.625e-95	326.0	COG1319@1|root,COG2931@1|root,COG3420@1|root,COG1319@2|Bacteria,COG2931@2|Bacteria,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	FAD_binding_5
CMS1_k127_1995158_2	634956.Geoth_2354	2.12e-105	362.0	COG0146@1|root,COG0146@2|Bacteria,1U1N7@1239|Firmicutes,4HBKB@91061|Bacilli,1WG3U@129337|Geobacillus	91061|Bacilli	EQ	acetone carboxylase, alpha subunit	-	-	6.4.1.6	ko:K10854	-	-	-	-	ko00000,ko01000	-	-	-	Hydantoinase_B
CMS1_k127_1995158_1	635013.TherJR_2510	9.729e-139	460.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,248JC@186801|Clostridia,261CY@186807|Peptococcaceae	186801|Clostridia	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C,AP_endonuc_2
CMS1_k127_1995158_0	634956.Geoth_2352	8.608e-212	681.0	COG0145@1|root,COG0145@2|Bacteria,1TQVB@1239|Firmicutes,4HB8X@91061|Bacilli,1WE3M@129337|Geobacillus	91061|Bacilli	EQ	Hydantoinase/oxoprolinase N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Hydant_A_N,Hydantoinase_A
CMS1_k127_1995158_3	634956.Geoth_2353	2.731e-60	219.0	COG4647@1|root,COG4647@2|Bacteria,1TTB5@1239|Firmicutes,4HCXE@91061|Bacilli,1WFHH@129337|Geobacillus	91061|Bacilli	Q	Acetone carboxylase gamma	-	-	6.4.1.6	ko:K10856	-	-	-	-	ko00000,ko01000	-	-	-	Acetone_carb_G
CMS1_k127_1995158_4	1122604.JONR01000001_gene1715	7.794e-42	170.0	COG2207@1|root,COG2207@2|Bacteria,1MX23@1224|Proteobacteria,1RRXM@1236|Gammaproteobacteria,1X9AC@135614|Xanthomonadales	135614|Xanthomonadales	K	Arabinose-binding domain of AraC transcription regulator, N-term	-	-	-	-	-	-	-	-	-	-	-	-	Arabinose_bd,HTH_18
CMS1_k127_1995158_5	237368.SCABRO_03851	7.816e-20	100.0	COG2165@1|root,COG2165@2|Bacteria,2J0Q6@203682|Planctomycetes	203682|Planctomycetes	U	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CMS1_k127_2002307_0	1125863.JAFN01000001_gene2376	2.662e-24	106.0	COG1186@1|root,COG1186@2|Bacteria,1ND5C@1224|Proteobacteria,430VS@68525|delta/epsilon subdivisions,2WW3U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	PFAM Class I peptide chain release factor	-	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
CMS1_k127_2008373_1	1487921.DP68_03095	2.814e-35	137.0	COG4409@1|root,COG4692@1|root,COG4409@2|Bacteria,COG4692@2|Bacteria,1UZJR@1239|Firmicutes,24CZ3@186801|Clostridia,36GR0@31979|Clostridiaceae	186801|Clostridia	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
CMS1_k127_2008373_0	1123242.JH636438_gene5874	5.343e-128	422.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	3.1.1.11	ko:K01051	ko00040,ko01100,map00040,map01100	M00081	R02362	RC00460,RC00461	ko00000,ko00001,ko00002,ko01000	-	-	-	CBM_6,Cadherin,DUF1929,HemolysinCabind,Malectin,Metallophos,PA14,Pur_ac_phosph_N
CMS1_k127_2021796_3	525904.Tter_1978	4.344e-52	194.0	COG1402@1|root,COG1402@2|Bacteria,2NRPM@2323|unclassified Bacteria	2|Bacteria	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
CMS1_k127_2021796_4	649638.Trad_2636	4.626e-09	68.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	CHU_C,Calx-beta,DUF5011,Glyco_hydro_18,PKD,SprB
CMS1_k127_2021796_2	243090.RB3353	4.369e-90	310.0	COG4409@1|root,COG4409@2|Bacteria,2IX8T@203682|Planctomycetes	203682|Planctomycetes	G	BNR repeat-like domain	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2
CMS1_k127_2021796_1	886293.Sinac_2603	3.394e-108	359.0	COG2120@1|root,COG2120@2|Bacteria,2IY80@203682|Planctomycetes	203682|Planctomycetes	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
CMS1_k127_2021796_0	357808.RoseRS_0437	6.37e-207	656.0	COG0029@1|root,COG0029@2|Bacteria,2G5JM@200795|Chloroflexi,375AE@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	-	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
CMS1_k127_2023349_0	743721.Psesu_2525	1.336e-63	231.0	COG0491@1|root,COG0491@2|Bacteria,1MXKX@1224|Proteobacteria,1RR31@1236|Gammaproteobacteria,1X47R@135614|Xanthomonadales	135614|Xanthomonadales	S	Zn-dependent hydrolases including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS1_k127_2023349_1	1089551.KE386572_gene1348	3.564e-29	127.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CMS1_k127_2023380_6	926556.Echvi_0827	1.355e-06	54.0	COG4974@1|root,COG4974@2|Bacteria,4NGQW@976|Bacteroidetes,47JJY@768503|Cytophagia	976|Bacteroidetes	L	Belongs to the 'phage' integrase family	xerC	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
CMS1_k127_2023380_0	497965.Cyan7822_0107	7.278e-240	771.0	COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,1G092@1117|Cyanobacteria,3KGR1@43988|Cyanothece	1117|Cyanobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
CMS1_k127_2023380_5	574087.Acear_1654	7.311e-07	57.0	COG2922@1|root,COG2922@2|Bacteria	2|Bacteria	S	Belongs to the Smg family	smg	-	-	ko:K03747	-	-	-	-	ko00000	-	-	-	DUF494
CMS1_k127_2023380_3	290397.Adeh_1235	3.824e-23	100.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,42V0K@68525|delta/epsilon subdivisions,2WR92@28221|Deltaproteobacteria,2Z1SJ@29|Myxococcales	28221|Deltaproteobacteria	K	Cold shock protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
CMS1_k127_2023380_7	509191.AEDB02000066_gene758	4.983e-06	60.0	COG5492@1|root,COG5492@2|Bacteria,1UITQ@1239|Firmicutes,25ER8@186801|Clostridia,3WSI6@541000|Ruminococcaceae	186801|Clostridia	N	dockerin type	-	-	4.2.2.23	ko:K18197	-	-	-	-	ko00000,ko01000	-	PL11	-	CBM_6,Dockerin_1
CMS1_k127_2023380_1	388051.AUFE01000056_gene4865	7.14e-177	584.0	COG0421@1|root,COG0421@2|Bacteria,1P220@1224|Proteobacteria,2VNDM@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Spermine/spermidine synthase domain	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
CMS1_k127_2023380_2	381666.H16_A1622	1.347e-76	267.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,2VKBQ@28216|Betaproteobacteria,1K39I@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
CMS1_k127_2023380_4	1348114.OM33_12210	9.4e-21	104.0	COG0657@1|root,COG0657@2|Bacteria	2|Bacteria	I	acetylesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,COesterase,DUF1080,Lipase_GDSL_2,Peptidase_S9
CMS1_k127_2029010_10	1340493.JNIF01000003_gene3874	6.345e-45	172.0	COG0572@1|root,COG0572@2|Bacteria,3Y4EI@57723|Acidobacteria	57723|Acidobacteria	F	Belongs to the uridine kinase family	-	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
CMS1_k127_2029010_0	485913.Krac_9719	1.091e-288	931.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2G7P2@200795|Chloroflexi	200795|Chloroflexi	KLT	SMART serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_16,TPR_2,TPR_8,WD40
CMS1_k127_2029010_8	383372.Rcas_0758	1.482e-92	317.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CMS1_k127_2029010_11	159087.Daro_2742	3.554e-43	167.0	COG4912@1|root,COG4912@2|Bacteria,1QR4Q@1224|Proteobacteria,2VTTV@28216|Betaproteobacteria,2KZ1W@206389|Rhodocyclales	206389|Rhodocyclales	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
CMS1_k127_2029010_2	338963.Pcar_2835	1.062e-184	587.0	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,42MZN@68525|delta/epsilon subdivisions,2WJGK@28221|Deltaproteobacteria,43SZD@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Belongs to the RtcB family	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
CMS1_k127_2029010_9	368407.Memar_1765	2.054e-53	192.0	COG1047@1|root,arCOG00981@2157|Archaea,2XXFW@28890|Euryarchaeota,2NAZY@224756|Methanomicrobia	224756|Methanomicrobia	O	peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C
CMS1_k127_2029010_5	1499967.BAYZ01000093_gene4010	5.573e-141	456.0	COG0673@1|root,COG0673@2|Bacteria,2NR2Z@2323|unclassified Bacteria	2|Bacteria	S	Homoserine dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_2029010_3	1499967.BAYZ01000093_gene4011	1.896e-180	570.0	COG0673@1|root,COG0673@2|Bacteria,2NRE6@2323|unclassified Bacteria	2|Bacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	1.1.99.28	ko:K00118	-	-	-	-	ko00000,ko01000	-	-	-	GFO_IDH_MocA
CMS1_k127_2029010_6	1131814.JAFO01000001_gene3552	2.081e-133	437.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TR7Q@28211|Alphaproteobacteria,3EYS2@335928|Xanthobacteraceae	28211|Alphaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
CMS1_k127_2029010_1	290397.Adeh_1417	8.262e-242	763.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42PMK@68525|delta/epsilon subdivisions,2X5G7@28221|Deltaproteobacteria,2Z35F@29|Myxococcales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS1_k127_2029010_4	886293.Sinac_6998	4.7e-153	501.0	COG3250@1|root,COG3250@2|Bacteria,2J54D@203682|Planctomycetes	203682|Planctomycetes	G	Pfam:DUF303	-	-	3.1.1.53	ko:K05970	-	-	-	-	ko00000,ko01000	-	-	-	SASA
CMS1_k127_2029010_12	489825.LYNGBM3L_01330	2.176e-05	55.0	2E14K@1|root,32WJQ@2|Bacteria,1G825@1117|Cyanobacteria,1HGGM@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2029010_7	1185876.BN8_02790	6.362e-106	355.0	COG2146@1|root,COG2717@1|root,COG2146@2|Bacteria,COG2717@2|Bacteria,4NJUW@976|Bacteroidetes,47TAG@768503|Cytophagia	976|Bacteroidetes	P	Ferric reductase like transmembrane component	-	-	-	-	-	-	-	-	-	-	-	-	Ferric_reduct,Rieske
CMS1_k127_2032909_2	497964.CfE428DRAFT_3173	4.155e-59	213.0	COG0673@1|root,COG0673@2|Bacteria,46TMF@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_2032909_3	1123368.AUIS01000010_gene2379	2.26e-35	143.0	COG2259@1|root,COG2259@2|Bacteria,1MZVP@1224|Proteobacteria,1S8UI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	membrane	yqjF	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
CMS1_k127_2032909_1	756272.Plabr_1989	1.413e-99	329.0	COG1741@1|root,COG1741@2|Bacteria,2IX1N@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
CMS1_k127_2032909_0	96561.Dole_1932	4.197e-130	437.0	COG0204@1|root,COG1647@1|root,COG0204@2|Bacteria,COG1647@2|Bacteria,1MVZP@1224|Proteobacteria,42NBK@68525|delta/epsilon subdivisions,2WIUP@28221|Deltaproteobacteria,2MHMP@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Phosphate acyltransferases	-	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Acyltransferase,Hydrolase_4
CMS1_k127_2037568_4	620914.JH621247_gene2946	1.069e-61	223.0	2EBZG@1|root,335YS@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2037568_5	237368.SCABRO_01890	2.958e-22	98.0	2E4RC@1|root,32ZJW@2|Bacteria,2J1K6@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2037568_0	234267.Acid_2264	3.267e-195	621.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_2,PSCyt2,PSD1
CMS1_k127_2037568_1	234267.Acid_2265	1.087e-182	582.0	COG4102@1|root,COG4102@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CMS1_k127_2037568_2	234267.Acid_2266	9.183e-167	552.0	COG2319@1|root,COG2319@2|Bacteria	2|Bacteria	S	anaphase-promoting complex binding	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,WD40
CMS1_k127_2037568_3	765912.Thimo_0664	3.012e-121	411.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
CMS1_k127_204920_1	515635.Dtur_0951	9.73e-24	108.0	COG0682@1|root,COG0682@2|Bacteria	2|Bacteria	M	lipoprotein biosynthetic process	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
CMS1_k127_204920_3	1345697.M493_05780	4.008e-19	93.0	COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,4HIR4@91061|Bacilli,1WG71@129337|Geobacillus	91061|Bacilli	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
CMS1_k127_204920_2	530564.Psta_0921	2.133e-19	92.0	COG1734@1|root,COG1734@2|Bacteria,2J04D@203682|Planctomycetes	203682|Planctomycetes	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
CMS1_k127_204920_0	439235.Dalk_1770	6.062e-212	677.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,42MKB@68525|delta/epsilon subdivisions,2WJ4W@28221|Deltaproteobacteria,2MI4Z@213118|Desulfobacterales	28221|Deltaproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
CMS1_k127_2052297_0	344747.PM8797T_17397	5.525e-153	489.0	COG1482@1|root,COG1482@2|Bacteria,2IYEB@203682|Planctomycetes	203682|Planctomycetes	G	cell wall glycoprotein biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2052297_1	156889.Mmc1_1104	3.09e-19	91.0	COG3000@1|root,COG3000@2|Bacteria,1MW5G@1224|Proteobacteria,2TU63@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	COG3000 Sterol desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
CMS1_k127_206805_1	314230.DSM3645_26724	3.158e-112	394.0	COG0457@1|root,COG0457@2|Bacteria,2IWTH@203682|Planctomycetes	203682|Planctomycetes	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2,TPR_16,TPR_19
CMS1_k127_206805_2	243090.RB8171	9.466e-76	263.0	2DBN7@1|root,2ZA2Y@2|Bacteria,2IYBW@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
CMS1_k127_206805_0	639030.JHVA01000001_gene1282	2.824e-123	404.0	COG0714@1|root,COG0714@2|Bacteria,3Y3BH@57723|Acidobacteria,2JP47@204432|Acidobacteriia	204432|Acidobacteriia	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS1_k127_206805_3	886293.Sinac_0404	4.983e-66	237.0	COG1721@1|root,COG1721@2|Bacteria,2IY8R@203682|Planctomycetes	203682|Planctomycetes	S	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CMS1_k127_206805_4	1267535.KB906767_gene910	1.269e-15	85.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
CMS1_k127_2071151_7	1303518.CCALI_00896	1.139e-57	215.0	COG3356@1|root,COG3356@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
CMS1_k127_2071151_6	1303518.CCALI_00896	3.544e-73	263.0	COG3356@1|root,COG3356@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
CMS1_k127_2071151_2	697281.Mahau_1202	5.222e-129	421.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,42F38@68295|Thermoanaerobacterales	186801|Clostridia	P	TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
CMS1_k127_2071151_4	1304880.JAGB01000002_gene2307	4.223e-121	398.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia	186801|Clostridia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
CMS1_k127_2071151_1	309799.DICTH_1598	7.536e-134	442.0	COG1173@1|root,COG1173@2|Bacteria	2|Bacteria	P	ABC-type dipeptide oligopeptide nickel transport systems, permease components	oppC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
CMS1_k127_2071151_3	706587.Desti_5628	1.995e-126	413.0	COG0601@1|root,COG0601@2|Bacteria,1NS80@1224|Proteobacteria,42N5D@68525|delta/epsilon subdivisions,2WIRR@28221|Deltaproteobacteria,2MQBC@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_2071151_9	1254432.SCE1572_50340	3.2e-31	139.0	COG5285@1|root,COG5285@2|Bacteria	2|Bacteria	Q	dioxygenase activity	-	-	1.14.11.18,1.14.11.55	ko:K00477,ko:K10674	ko00260,ko01120,ko04146,map00260,map01120,map04146	-	R08050	RC00661	ko00000,ko00001,ko01000	-	-	-	PhyH
CMS1_k127_2071151_5	485914.Hmuk_3414	2.041e-75	265.0	COG0613@1|root,arCOG00302@2157|Archaea	2157|Archaea	E	metal-dependent phosphoesterases (PHP family)	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux,CarboxypepD_reg,DDOST_48kD
CMS1_k127_2071151_10	243090.RB12264	1.709e-24	107.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS1_k127_2071151_8	1282876.BAOK01000001_gene2274	3.228e-45	174.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2U73Z@28211|Alphaproteobacteria,4BQ9M@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	K	Belongs to the P(II) protein family	glnB	GO:0003674,GO:0006808,GO:0008150,GO:0030234,GO:0050789,GO:0050790,GO:0065007,GO:0065009,GO:0098772	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
CMS1_k127_2071151_0	665571.STHERM_c02830	1.291e-218	686.0	COG0174@1|root,COG0174@2|Bacteria,2J6JS@203691|Spirochaetes	203691|Spirochaetes	E	PFAM Glutamine synthetase, catalytic domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
CMS1_k127_2075533_1	240015.ACP_2407	5.189e-18	87.0	COG0542@1|root,COG0542@2|Bacteria,3Y2X9@57723|Acidobacteria,2JIAE@204432|Acidobacteriia	204432|Acidobacteriia	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
CMS1_k127_2075533_0	926554.KI912674_gene2647	4.342e-110	364.0	COG0031@1|root,COG0031@2|Bacteria,1WJ3S@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Belongs to the cysteine synthase cystathionine beta- synthase family	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS1_k127_2075533_2	247490.KSU1_C1333	3.264e-16	90.0	COG4968@1|root,COG4968@2|Bacteria,2J519@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CMS1_k127_2075533_3	247490.KSU1_C1333	1.777e-15	88.0	COG4968@1|root,COG4968@2|Bacteria,2J519@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CMS1_k127_2076902_6	1463857.JOFZ01000001_gene5920	1.786e-16	93.0	COG0151@1|root,COG0151@2|Bacteria,2GKTF@201174|Actinobacteria	201174|Actinobacteria	F	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4
CMS1_k127_2076902_0	273068.TTE2002	4.222e-202	641.0	COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,42FD3@68295|Thermoanaerobacterales	186801|Clostridia	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
CMS1_k127_2076902_2	762968.HMPREF9441_00891	2.63e-54	198.0	COG2755@1|root,COG2755@2|Bacteria,4NPAF@976|Bacteroidetes,2FRRW@200643|Bacteroidia	976|Bacteroidetes	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL,Lipase_GDSL_2
CMS1_k127_2076902_5	446469.Sked_27320	5.01e-28	124.0	COG0451@1|root,COG0451@2|Bacteria,2GN5E@201174|Actinobacteria	201174|Actinobacteria	GM	Epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
CMS1_k127_2076902_1	1121430.JMLG01000002_gene1318	2.785e-117	396.0	COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,248A9@186801|Clostridia,260CJ@186807|Peptococcaceae	186801|Clostridia	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
CMS1_k127_2076902_4	349161.Dred_3325	3.14e-29	131.0	COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,249EA@186801|Clostridia,260UK@186807|Peptococcaceae	186801|Clostridia	S	PFAM Single-stranded nucleic acid binding R3H	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
CMS1_k127_2076902_3	237368.SCABRO_03331	8.951e-37	146.0	COG0706@1|root,COG0706@2|Bacteria,2IYA0@203682|Planctomycetes	203682|Planctomycetes	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,PDZ_2,YidC_periplas
CMS1_k127_2088767_14	1116472.MGMO_39c00130	0.0002915	50.0	COG3637@1|root,COG3637@2|Bacteria,1R64D@1224|Proteobacteria,1S325@1236|Gammaproteobacteria,1XDN4@135618|Methylococcales	135618|Methylococcales	M	Alginate export	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp
CMS1_k127_2088767_8	661367.LLO_1689	2.47e-38	154.0	COG2928@1|root,COG2928@2|Bacteria,1MWT5@1224|Proteobacteria,1S3MU@1236|Gammaproteobacteria,1JCMJ@118969|Legionellales	118969|Legionellales	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
CMS1_k127_2088767_6	195103.CPF_0036	8.164e-66	242.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,36F3D@31979|Clostridiaceae	186801|Clostridia	S	CBS domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
CMS1_k127_2088767_5	574087.Acear_0620	3.229e-75	275.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,3WAE6@53433|Halanaerobiales	186801|Clostridia	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
CMS1_k127_2088767_12	1385510.N781_11210	3.389e-20	98.0	COG0319@1|root,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,4HIIE@91061|Bacilli,2YAB7@289201|Pontibacillus	91061|Bacilli	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
CMS1_k127_2088767_4	1121422.AUMW01000027_gene453	4.217e-78	292.0	COG1480@1|root,COG1480@2|Bacteria,1TR1A@1239|Firmicutes,249W0@186801|Clostridia,2610I@186807|Peptococcaceae	186801|Clostridia	S	7TM receptor with intracellular HD hydrolase	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
CMS1_k127_2088767_3	562970.Btus_0771	1.365e-98	332.0	COG1702@1|root,COG1702@2|Bacteria,1TP35@1239|Firmicutes,4HBD5@91061|Bacilli,2785Z@186823|Alicyclobacillaceae	91061|Bacilli	T	AAA domain	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
CMS1_k127_2088767_0	243231.GSU2286	6.049e-192	607.0	COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,42MS9@68525|delta/epsilon subdivisions,2WJMS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
CMS1_k127_2088767_10	373903.Hore_21140	9.598e-26	119.0	COG0760@1|root,COG0760@2|Bacteria,1TX3R@1239|Firmicutes,25C37@186801|Clostridia,3WAP3@53433|Halanaerobiales	186801|Clostridia	M	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03769,ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Cu_amine_oxidN1,Rotamase_2,Rotamase_3,SurA_N_3
CMS1_k127_2088767_2	909663.KI867150_gene68	1.766e-114	390.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,42N87@68525|delta/epsilon subdivisions,2WK1B@28221|Deltaproteobacteria,2MRH3@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	ABC1 family	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,APH
CMS1_k127_2088767_7	562970.Btus_0064	1.09e-62	232.0	COG1947@1|root,COG1947@2|Bacteria,1TPXV@1239|Firmicutes,4HAV8@91061|Bacilli,277ZR@186823|Alicyclobacillaceae	91061|Bacilli	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096,M00582	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.29	-	iYO844.BSU00460	GHMP_kinases_C,GHMP_kinases_N
CMS1_k127_2088767_13	1125863.JAFN01000001_gene475	1.998e-19	102.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	PFAM Type II secretion system protein E	-	-	-	-	-	-	-	-	-	-	-	-	GAF,T2SSE,T2SSE_N
CMS1_k127_2088767_9	293826.Amet_0771	1.931e-31	140.0	COG1639@1|root,COG1639@2|Bacteria,1TPRT@1239|Firmicutes,249CG@186801|Clostridia,36FX7@31979|Clostridiaceae	186801|Clostridia	T	PFAM metal-dependent phosphohydrolase HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD,Response_reg
CMS1_k127_2088767_11	1343739.PAP_06920	1.029e-23	108.0	COG1896@1|root,arCOG04311@2157|Archaea,2XX7G@28890|Euryarchaeota,2440T@183968|Thermococci	183968|Thermococci	S	HD domain	-	-	-	ko:K07023	-	-	-	-	ko00000	-	-	-	HD_3
CMS1_k127_2088767_1	935948.KE386493_gene2309	4.015e-151	499.0	COG1874@1|root,COG1874@2|Bacteria,1TQN6@1239|Firmicutes,2488V@186801|Clostridia,42FYE@68295|Thermoanaerobacterales	186801|Clostridia	G	PFAM Glycoside hydrolase family 42 domain protein	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
CMS1_k127_2091273_0	1122917.KB899661_gene1195	1.351e-204	649.0	COG1262@1|root,COG4409@1|root,COG1262@2|Bacteria,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2,FGE-sulfatase
CMS1_k127_2099837_1	1122947.FR7_3674	3.081e-05	55.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H2ND@909932|Negativicutes	909932|Negativicutes	V	PFAM ABC transporter transmembrane region, ABC transporter related protein	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS1_k127_2099837_0	1535422.ND16A_2082	1.803e-81	289.0	COG2801@1|root,COG2801@2|Bacteria,1MXKK@1224|Proteobacteria,1RSMZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	PFAM Integrase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2102999_1	1184267.A11Q_2194	1.681e-71	250.0	COG2303@1|root,COG2303@2|Bacteria,1QQ8F@1224|Proteobacteria,42PWF@68525|delta/epsilon subdivisions,2MTM7@213481|Bdellovibrionales,2WKVA@28221|Deltaproteobacteria	213481|Bdellovibrionales	E	GMC oxidoreductase	choD	-	1.1.3.6	ko:K03333	ko00984,ko01120,map00984,map01120	-	R01459	RC00146	ko00000,ko00001,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
CMS1_k127_2102999_0	391615.ABSJ01000005_gene605	2.456e-144	469.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	belongs to the aldehyde dehydrogenase family	-	-	1.2.99.10	ko:K22445	-	-	-	-	ko00000,ko01000	-	-	-	Aldedh
CMS1_k127_2114596_2	1304275.C41B8_16964	3.694e-09	61.0	2EKEB@1|root,33E4I@2|Bacteria,1Q16Q@1224|Proteobacteria,1SGYM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2114596_3	395964.KE386496_gene1657	8.86e-06	48.0	COG3385@1|root,COG3385@2|Bacteria,1QURV@1224|Proteobacteria,2TW56@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG2183 Transcriptional accessory protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
CMS1_k127_2114596_1	1298867.AUES01000045_gene3549	1.092e-43	161.0	COG4274@1|root,COG4274@2|Bacteria,1RJBN@1224|Proteobacteria,2UIN0@28211|Alphaproteobacteria,3K1Q3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
CMS1_k127_2114596_0	867903.ThesuDRAFT_02227	2.02e-69	241.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,3WDK0@538999|Clostridiales incertae sedis	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
CMS1_k127_2126012_1	575540.Isop_2634	2.712e-158	511.0	COG1850@1|root,COG1850@2|Bacteria	2|Bacteria	G	ribulose-bisphosphate carboxylase activity	cbbL	-	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
CMS1_k127_2126012_3	1122132.AQYH01000003_gene3144	1.382e-136	451.0	COG0673@1|root,COG0673@2|Bacteria,1MWNK@1224|Proteobacteria,2UP2F@28211|Alphaproteobacteria,4B745@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_2126012_8	1089551.KE386572_gene2868	2.083e-71	254.0	COG1082@1|root,COG1082@2|Bacteria,1N1AK@1224|Proteobacteria,2U3TU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS1_k127_2126012_7	886293.Sinac_2235	1.412e-81	280.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
CMS1_k127_2126012_10	1267535.KB906767_gene189	5.08e-48	181.0	COG0036@1|root,COG0036@2|Bacteria	2|Bacteria	G	ribulose-phosphate 3-epimerase activity	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
CMS1_k127_2126012_9	573413.Spirs_0493	2.272e-67	245.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	ko:K05820	-	-	-	-	ko00000,ko02000	2.A.1.27	-	-	Nuc_H_symport
CMS1_k127_2126012_12	349521.HCH_00444	7.511e-30	120.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,1SCKA@1236|Gammaproteobacteria,1XKZ1@135619|Oceanospirillales	135619|Oceanospirillales	S	RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
CMS1_k127_2126012_5	583355.Caka_2352	5.552e-93	316.0	COG1611@1|root,COG1611@2|Bacteria,46T2W@74201|Verrucomicrobia,3K8G4@414999|Opitutae	414999|Opitutae	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
CMS1_k127_2126012_6	326427.Cagg_3388	9.811e-88	303.0	COG0012@1|root,COG0012@2|Bacteria,2G5UY@200795|Chloroflexi,376AC@32061|Chloroflexia	32061|Chloroflexia	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
CMS1_k127_2126012_11	706587.Desti_4300	1.618e-36	149.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CMS1_k127_2126012_13	1123288.SOV_5c01010	7.978e-30	127.0	COG2020@1|root,COG2020@2|Bacteria,1V495@1239|Firmicutes	1239|Firmicutes	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
CMS1_k127_2126012_15	643867.Ftrac_2857	5.635e-14	84.0	COG1657@1|root,COG1657@2|Bacteria,4PAEX@976|Bacteroidetes,47TET@768503|Cytophagia	976|Bacteroidetes	I	PFAM Prenyltransferase squalene oxidase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2126012_14	1232410.KI421424_gene1760	2.926e-28	124.0	COG2010@1|root,COG2010@2|Bacteria,1QYFZ@1224|Proteobacteria,43CC3@68525|delta/epsilon subdivisions,2WQTQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2126012_4	448385.sce4705	1.767e-123	403.0	COG0437@1|root,COG0437@2|Bacteria,1NBU3@1224|Proteobacteria,42MNU@68525|delta/epsilon subdivisions,2WJRG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	dsrO	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11,Fer4_4
CMS1_k127_2126012_2	583355.Caka_0068	5.001e-144	468.0	COG5557@1|root,COG5557@2|Bacteria	2|Bacteria	C	Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
CMS1_k127_2126012_0	2340.JV46_09630	8.433e-205	648.0	COG3303@1|root,COG3303@2|Bacteria,1P8CP@1224|Proteobacteria,1RQGG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Seven times multi-haem cytochrome CxxCH	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Multi-haem_cyto
CMS1_k127_2132674_3	1379698.RBG1_1C00001G0393	9.944e-80	282.0	COG0472@1|root,COG0472@2|Bacteria,2NNQW@2323|unclassified Bacteria	2|Bacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	iAF987.Gmet_0409,iEC042_1314.EC042_0088,iECABU_c1320.ECABU_c00920,iECED1_1282.ECED1_0088,iECH74115_1262.ECH74115_0095,iECSP_1301.ECSP_0090,iECs_1301.ECs0091,iG2583_1286.G2583_0091,iSDY_1059.SDY_0117,iZ_1308.Z0097,ic_1306.c0105	Glycos_transf_4,MraY_sig1
CMS1_k127_2132674_1	1121468.AUBR01000006_gene362	7.724e-100	341.0	COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,248GS@186801|Clostridia,42EZQ@68295|Thermoanaerobacterales	186801|Clostridia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
CMS1_k127_2132674_4	338963.Pcar_2203	2.721e-79	278.0	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,42MG2@68525|delta/epsilon subdivisions,2WJ01@28221|Deltaproteobacteria,43TAE@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Peptidoglycan polymerase that is essential for cell division	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
CMS1_k127_2132674_5	696281.Desru_3347	2.182e-73	260.0	COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,248IA@186801|Clostridia,260TT@186807|Peptococcaceae	186801|Clostridia	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
CMS1_k127_2132674_7	744872.Spica_0917	2.913e-63	224.0	COG0274@1|root,COG0274@2|Bacteria,2J7GA@203691|Spirochaetes	203691|Spirochaetes	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
CMS1_k127_2132674_6	876044.IMCC3088_784	1.463e-64	240.0	COG1914@1|root,COG1914@2|Bacteria,1R6Y2@1224|Proteobacteria,1S0IP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	COG1914 Mn2 and Fe2 transporters of the NRAMP family	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
CMS1_k127_2132674_0	1123242.JH636435_gene2066	3.107e-125	427.0	COG2366@1|root,COG2366@2|Bacteria,2J08A@203682|Planctomycetes	203682|Planctomycetes	S	Penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
CMS1_k127_2132674_2	344747.PM8797T_03059	6.127e-85	298.0	COG5434@1|root,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_lyase,Beta_helix,Glyco_hydro_28,Pectate_lyase_3
CMS1_k127_2132702_0	456442.Mboo_0643	3.682e-47	191.0	COG2208@1|root,arCOG02362@1|root,arCOG02362@2157|Archaea,arCOG06893@2157|Archaea	2157|Archaea	KT	stage II sporulation	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HAMP,SpoIIE,dCache_1
CMS1_k127_2132702_1	404589.Anae109_0333	2.366e-05	50.0	2CHM7@1|root,2ZV0T@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2138559_13	290400.Jann_1467	1.373e-07	60.0	COG0673@1|root,COG0673@2|Bacteria,1R4MU@1224|Proteobacteria,2TRCX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_2138559_7	584708.Apau_0860	5.852e-67	243.0	COG1868@1|root,COG1868@2|Bacteria,3TA6T@508458|Synergistetes	508458|Synergistetes	N	TIGRFAM flagellar motor switch protein FliM	-	-	-	ko:K02416	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliM,FliMN_C
CMS1_k127_2138559_10	1184267.A11Q_608	1.57e-25	111.0	COG1886@1|root,COG1886@2|Bacteria,1RGWT@1224|Proteobacteria,42TQB@68525|delta/epsilon subdivisions,2MT4T@213481|Bdellovibrionales,2WQCQ@28221|Deltaproteobacteria	213481|Bdellovibrionales	N	Flagellar motor switch protein FliN	fliN	-	-	ko:K02417	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FliMN_C
CMS1_k127_2138559_3	1499967.BAYZ01000118_gene3242	5.738e-105	353.0	COG2017@1|root,COG2017@2|Bacteria,2NQQX@2323|unclassified Bacteria	2|Bacteria	G	Domain of unknown function (DUF4432)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4432
CMS1_k127_2138559_14	626418.bglu_1g11660	4.975e-07	63.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2VJ3Z@28216|Betaproteobacteria,1KIFW@119060|Burkholderiaceae	28216|Betaproteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,HATPase_c,HisKA,PAS,PAS_10,Response_reg
CMS1_k127_2138559_2	1379698.RBG1_1C00001G1403	1.977e-112	377.0	COG2133@1|root,COG2133@2|Bacteria,2NNSP@2323|unclassified Bacteria	2|Bacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,GSDH
CMS1_k127_2138559_8	1292034.OR37_00695	2.38e-33	147.0	COG3290@1|root,COG3920@1|root,COG3290@2|Bacteria,COG3920@2|Bacteria,1NU8D@1224|Proteobacteria,2U6IX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HWE_HK,PAS_3,PAS_4
CMS1_k127_2138559_5	391625.PPSIR1_23399	1.059e-73	268.0	COG4191@1|root,COG4191@2|Bacteria,1R609@1224|Proteobacteria,42MTJ@68525|delta/epsilon subdivisions,2WJYM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	COG0515 Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Pkinase
CMS1_k127_2138559_0	243231.GSU1039	2.149e-152	500.0	COG2204@1|root,COG3829@1|root,COG2204@2|Bacteria,COG3829@2|Bacteria,1MU0N@1224|Proteobacteria,43BK2@68525|delta/epsilon subdivisions,2X6XX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Sigma-54 factor interaction domain-containing protein	-	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,PAS_4,Response_reg,Sigma54_activat
CMS1_k127_2138559_4	484770.UFO1_4039	2.438e-94	321.0	COG0280@1|root,COG0280@2|Bacteria,1TPQ0@1239|Firmicutes,4H3V6@909932|Negativicutes	909932|Negativicutes	C	phosphate acetyltransferase	pta	-	2.3.1.8	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTA_PTB
CMS1_k127_2138559_1	246194.CHY_1455	3.296e-120	398.0	COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia,42EXA@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
CMS1_k127_2138559_6	1110502.TMO_0988	2.785e-71	245.0	COG0259@1|root,COG0259@2|Bacteria,1NZUU@1224|Proteobacteria,2TT1U@28211|Alphaproteobacteria,2JRUZ@204441|Rhodospirillales	204441|Rhodospirillales	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	pdxH	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
CMS1_k127_2138559_9	1379698.RBG1_1C00001G0797	7.81e-33	134.0	COG4191@1|root,COG4191@2|Bacteria,2NS4C@2323|unclassified Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9,Response_reg
CMS1_k127_2138559_11	573413.Spirs_0310	6.751e-16	89.0	COG0407@1|root,COG0407@2|Bacteria,2JA7B@203691|Spirochaetes	203691|Spirochaetes	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
CMS1_k127_2138559_12	1265505.ATUG01000001_gene4678	1.126e-12	72.0	COG0584@1|root,COG1409@1|root,COG0584@2|Bacteria,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD,GDPD_2,Metallophos,Pur_ac_phosph_N
CMS1_k127_2142085_1	640512.BC1003_4717	6.69e-84	284.0	COG0641@1|root,COG0641@2|Bacteria,1MX3M@1224|Proteobacteria,2VYFJ@28216|Betaproteobacteria,1K4C2@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Radical SAM superfamily	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
CMS1_k127_2142085_0	547163.BN979_04247	0.0	1113.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria,233CA@1762|Mycobacteriaceae	201174|Actinobacteria	P	thought to play an important role in the mineralization of sulfates catalytic activity a phenol sulfate H2O a phenol sulfate	atsB	GO:0000323,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0004065,GO:0004098,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005766,GO:0005773,GO:0005775,GO:0005783,GO:0005788,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006687,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008150,GO:0008152,GO:0008484,GO:0009987,GO:0012505,GO:0016192,GO:0016787,GO:0016788,GO:0030141,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032940,GO:0034774,GO:0035578,GO:0036230,GO:0042119,GO:0042582,GO:0043167,GO:0043169,GO:0043202,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0044237,GO:0044238,GO:0044255,GO:0044422,GO:0044424,GO:0044432,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046872,GO:0046903,GO:0050896,GO:0051179,GO:0051234,GO:0060205,GO:0070013,GO:0071704,GO:0097708,GO:0099503,GO:1901135,GO:1901564,GO:1903509	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	DUF1269,Sulfatase
CMS1_k127_2142896_0	1121904.ARBP01000005_gene4837	3.826e-109	372.0	COG3356@1|root,COG3356@2|Bacteria,4NH6U@976|Bacteroidetes,47NFZ@768503|Cytophagia	976|Bacteroidetes	S	PFAM Neutral alkaline nonlysosomal ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
CMS1_k127_2155629_0	641491.DND132_2866	3.241e-183	619.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2WJ96@28221|Deltaproteobacteria,2M85Y@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	poR	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C
CMS1_k127_2157908_1	316274.Haur_3126	1.186e-132	447.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,2G5ZQ@200795|Chloroflexi,376AA@32061|Chloroflexia	32061|Chloroflexia	C	FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_8
CMS1_k127_2157908_0	1123278.KB893565_gene3529	2.488e-280	889.0	COG3391@1|root,COG3511@1|root,COG3391@2|Bacteria,COG3511@2|Bacteria,4NEFM@976|Bacteroidetes,47NY3@768503|Cytophagia	976|Bacteroidetes	M	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Phosphoesterase
CMS1_k127_2157908_2	1089547.KB913013_gene1013	1.301e-71	252.0	28M5E@1|root,2ZAJ7@2|Bacteria,4NZ10@976|Bacteroidetes,47TH9@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2160945_0	926550.CLDAP_13670	1.427e-77	279.0	COG1070@1|root,COG1070@2|Bacteria,2G7KS@200795|Chloroflexi	200795|Chloroflexi	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
CMS1_k127_2160945_1	497964.CfE428DRAFT_1032	6.117e-29	134.0	COG3170@1|root,COG3170@2|Bacteria,46W02@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2176513_5	344747.PM8797T_23599	4.326e-16	90.0	COG2010@1|root,COG2010@2|Bacteria,2J2MP@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
CMS1_k127_2176513_2	234267.Acid_5864	3.654e-61	224.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS1_k127_2176513_0	1340493.JNIF01000004_gene652	3.799e-238	752.0	COG2274@1|root,COG2274@2|Bacteria	2|Bacteria	V	protein secretion by the type I secretion system	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
CMS1_k127_2176513_6	760011.Spico_0734	2.796e-14	85.0	COG0477@1|root,COG2814@2|Bacteria,2JAP5@203691|Spirochaetes	203691|Spirochaetes	EGP	PFAM Major Facilitator Superfamily	-	-	-	ko:K08153,ko:K19576	-	M00717	-	-	ko00000,ko00002,ko02000	2.A.1.2.10,2.A.1.2.8	-	-	MFS_1
CMS1_k127_2176513_1	1288963.ADIS_4374	2.998e-226	726.0	28MHM@1|root,2ZAUH@2|Bacteria,4NKMG@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2176513_3	658086.HMPREF0994_06084	4.7e-41	172.0	COG3533@1|root,COG3533@2|Bacteria	2|Bacteria	S	Beta-L-arabinofuranosidase, GH127	-	-	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Alginate_lyase,CBM_35,Glyco_hydro_127,Glyco_hydro_25,Laminin_G_3,Methyltransf_11,Prenyltrans,RHS_repeat,RicinB_lectin_2
CMS1_k127_2176513_4	314230.DSM3645_28727	8.463e-32	129.0	COG0613@1|root,COG0613@2|Bacteria,2IZFJ@203682|Planctomycetes	203682|Planctomycetes	S	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2181048_1	1129794.C427_0356	5.523e-34	143.0	COG2207@1|root,COG2207@2|Bacteria,1QEFK@1224|Proteobacteria,1RYVP@1236|Gammaproteobacteria,46730@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	AraC family transcriptional regulator	-	-	-	ko:K18954	-	-	-	-	ko00000,ko03000	-	-	-	AraC_binding,HTH_18,HTH_AraC
CMS1_k127_2181048_0	661478.OP10G_2899	3.265e-51	200.0	COG2730@1|root,COG3291@1|root,COG2730@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_6,Cellulase,PA14
CMS1_k127_2181048_3	247490.KSU1_C1333	3.412e-16	90.0	COG4968@1|root,COG4968@2|Bacteria,2J519@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CMS1_k127_2181048_2	2423.NA23_0209490	4.755e-27	116.0	arCOG03622@1|root,33HZF@2|Bacteria,2GE37@200918|Thermotogae	200918|Thermotogae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2182129_0	653045.Strvi_3974	8.481e-54	206.0	COG2234@1|root,COG2234@2|Bacteria,2GJ67@201174|Actinobacteria	201174|Actinobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
CMS1_k127_2186510_2	479434.Sthe_0323	5.227e-17	96.0	COG4485@1|root,COG4485@2|Bacteria,2G75F@200795|Chloroflexi,27XT2@189775|Thermomicrobia	189775|Thermomicrobia	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
CMS1_k127_2186510_0	1121423.JONT01000002_gene2267	9.351e-119	398.0	COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,249R3@186801|Clostridia,264VH@186807|Peptococcaceae	186801|Clostridia	C	pyridine nucleotide-disulphide oxidoreductase dimerisation	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
CMS1_k127_2186510_1	421531.IX38_20515	1.332e-71	250.0	COG0508@1|root,COG0508@2|Bacteria,4NFB9@976|Bacteroidetes,1HZ6M@117743|Flavobacteriia,3ZPXE@59732|Chryseobacterium	976|Bacteroidetes	C	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex	pdhC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
CMS1_k127_2186797_0	1304872.JAGC01000003_gene2364	2.142e-123	410.0	28I8B@1|root,2Z8B5@2|Bacteria,1MUNM@1224|Proteobacteria,42NZH@68525|delta/epsilon subdivisions,2WKHB@28221|Deltaproteobacteria,2M9ZJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Cytochrome c bacterial	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_cB
CMS1_k127_2186797_1	1210884.HG799462_gene8853	3.045e-78	285.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
CMS1_k127_2186797_2	118173.KB235914_gene1216	1.697e-48	186.0	COG0642@1|root,COG2202@1|root,COG3829@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,1G09B@1117|Cyanobacteria,1H7M6@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GAF,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
CMS1_k127_2188395_0	1382306.JNIM01000001_gene3281	2.031e-124	410.0	COG3616@1|root,COG3616@2|Bacteria	2|Bacteria	E	Alanine racemase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Ala_racemase_N
CMS1_k127_2188395_1	383372.Rcas_3780	2.892e-117	386.0	COG0208@1|root,COG0208@2|Bacteria,2G610@200795|Chloroflexi,3761D@32061|Chloroflexia	32061|Chloroflexia	F	PFAM ribonucleotide reductase	-	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
CMS1_k127_2188395_4	314230.DSM3645_12436	1.451e-08	63.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
CMS1_k127_2188395_2	1246484.D479_00635	4.711e-55	206.0	COG0673@1|root,COG0673@2|Bacteria,1TQ72@1239|Firmicutes,4HCS4@91061|Bacilli,3NEJ6@45667|Halobacillus	91061|Bacilli	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_2188395_3	1463820.JOGW01000008_gene1728	1.152e-31	144.0	COG3345@1|root,COG3345@2|Bacteria,2GJJ1@201174|Actinobacteria	201174|Actinobacteria	G	alpha-galactosidase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_36N,Melibiase
CMS1_k127_2194125_7	697281.Mahau_1339	6.438e-40	154.0	COG0407@1|root,COG0407@2|Bacteria,1V4YU@1239|Firmicutes,24FCZ@186801|Clostridia,42HY1@68295|Thermoanaerobacterales	186801|Clostridia	H	PFAM Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
CMS1_k127_2194125_8	643867.Ftrac_0387	1.573e-24	107.0	COG2852@1|root,COG2852@2|Bacteria,4NQRT@976|Bacteroidetes,47X9B@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
CMS1_k127_2194125_5	1122222.AXWR01000028_gene939	3.444e-73	258.0	COG0407@1|root,COG0407@2|Bacteria,1WIHR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
CMS1_k127_2194125_2	317619.ANKN01000228_gene970	1.747e-111	386.0	COG1215@1|root,COG3222@1|root,COG1215@2|Bacteria,COG3222@2|Bacteria,1GDJY@1117|Cyanobacteria,1MKT4@1212|Prochloraceae	1117|Cyanobacteria	M	Alternative locus ID	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS1_k127_2194125_6	1305737.JAFX01000001_gene596	9.39e-68	256.0	COG1215@1|root,COG1215@2|Bacteria,4NFM1@976|Bacteroidetes,47M1F@768503|Cytophagia	976|Bacteroidetes	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS1_k127_2194125_0	179408.Osc7112_2732	1.372e-211	668.0	COG1249@1|root,COG1249@2|Bacteria,1G198@1117|Cyanobacteria,1H7PH@1150|Oscillatoriales	1117|Cyanobacteria	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase	merA	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim,SNARE_assoc
CMS1_k127_2194125_4	402777.KB235904_gene4448	6.822e-77	265.0	COG0398@1|root,COG0398@2|Bacteria,1G3PG@1117|Cyanobacteria,1H98G@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
CMS1_k127_2194125_3	313612.L8106_21674	3.3e-81	281.0	COG0398@1|root,COG0398@2|Bacteria,1G3R9@1117|Cyanobacteria,1H8VH@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function, DUF547	-	-	-	-	-	-	-	-	-	-	-	-	DUF547
CMS1_k127_2194125_1	324057.Pjdr2_4263	9.044e-119	406.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HTS6@91061|Bacilli,26U3J@186822|Paenibacillaceae	91061|Bacilli	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS1_k127_219955_1	304371.MCP_0999	2.67e-63	222.0	COG0778@1|root,arCOG00288@2157|Archaea,2XXW2@28890|Euryarchaeota,2N9TG@224756|Methanomicrobia	224756|Methanomicrobia	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CMS1_k127_219955_2	1288494.EBAPG3_15610	2.206e-47	173.0	COG1504@1|root,COG1504@2|Bacteria,1RGJ6@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF498/DUF598)	-	-	-	-	-	-	-	-	-	-	-	-	DUF498
CMS1_k127_219955_0	1123508.JH636443_gene4974	1.597e-92	309.0	COG3391@1|root,COG3391@2|Bacteria,2IX7F@203682|Planctomycetes	203682|Planctomycetes	M	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase,Phosphoesterase
CMS1_k127_2200312_4	1198114.AciX9_2973	1.27e-16	85.0	COG3682@1|root,COG3682@2|Bacteria,3Y51U@57723|Acidobacteria,2JJMK@204432|Acidobacteriia	204432|Acidobacteriia	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
CMS1_k127_2200312_2	278957.ABEA03000160_gene9	4.767e-66	251.0	COG0395@1|root,COG0395@2|Bacteria,46YDG@74201|Verrucomicrobia,3K9CV@414999|Opitutae	414999|Opitutae	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_2200312_1	794903.OPIT5_29145	1.919e-75	279.0	COG1175@1|root,COG1175@2|Bacteria,46Y9N@74201|Verrucomicrobia,3K96E@414999|Opitutae	414999|Opitutae	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
CMS1_k127_2200312_3	794903.OPIT5_15540	1.287e-60	232.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K02027,ko:K10117,ko:K17318	ko02010,map02010	M00196,M00207,M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.28,3.A.1.1.29,3.A.1.1.9	-	-	SBP_bac_1,SBP_bac_8
CMS1_k127_2200312_6	349521.HCH_05922	0.0007626	51.0	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,1RSE6@1236|Gammaproteobacteria,1XJHK@135619|Oceanospirillales	135619|Oceanospirillales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
CMS1_k127_2200312_0	658086.HMPREF0994_03992	2.462e-84	310.0	COG3525@1|root,COG3525@2|Bacteria	2|Bacteria	G	beta-N-acetylhexosaminidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4838,F5_F8_type_C,Glyco_hydro_67N
CMS1_k127_2200312_5	1121920.AUAU01000028_gene1383	1.128e-12	70.0	COG3682@1|root,COG3682@2|Bacteria,3Y5AK@57723|Acidobacteria	57723|Acidobacteria	K	PFAM Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
CMS1_k127_2201390_6	1353531.AZNX01000005_gene3327	2.769e-56	206.0	COG4287@1|root,COG4287@2|Bacteria,1NP5V@1224|Proteobacteria	1224|Proteobacteria	O	PhoPQ-activated pathogenicity-related protein	pqaA	-	-	-	-	-	-	-	-	-	-	-	PhoPQ_related
CMS1_k127_2201390_8	1234664.AMRO01000024_gene1765	2.125e-30	130.0	COG0212@1|root,COG0212@2|Bacteria,1VA91@1239|Firmicutes,4HM35@91061|Bacilli,1WFB2@129337|Geobacillus	91061|Bacilli	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	fthC	GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0030272,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
CMS1_k127_2201390_4	56780.SYN_02888	5.025e-78	275.0	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,42M7V@68525|delta/epsilon subdivisions,2WIUB@28221|Deltaproteobacteria,2MQEE@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
CMS1_k127_2201390_0	1120973.AQXL01000134_gene1653	3.015e-113	388.0	COG0323@1|root,COG0323@2|Bacteria,1TPGK@1239|Firmicutes,4HB34@91061|Bacilli,2782V@186823|Alicyclobacillaceae	91061|Bacilli	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
CMS1_k127_2201390_7	1174504.AJTN02000153_gene1027	2.072e-54	209.0	COG2182@1|root,COG2182@2|Bacteria,1UI6V@1239|Firmicutes,4ISFX@91061|Bacilli,1ZCIF@1386|Bacillus	91061|Bacilli	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_1,SBP_bac_8
CMS1_k127_2201390_1	697281.Mahau_2566	2.938e-105	349.0	COG1175@1|root,COG1175@2|Bacteria,1TPTZ@1239|Firmicutes,2492R@186801|Clostridia,42FXR@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_2201390_3	697281.Mahau_0771	5.986e-80	278.0	COG0395@1|root,COG0395@2|Bacteria,1TSAB@1239|Firmicutes,25C5T@186801|Clostridia,42JEU@68295|Thermoanaerobacterales	186801|Clostridia	P	COGs COG0395 ABC-type sugar transport system permease component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_2201390_5	158189.SpiBuddy_0323	5.28e-63	226.0	COG0483@1|root,COG0483@2|Bacteria,2J8G7@203691|Spirochaetes	203691|Spirochaetes	G	Inositol monophosphatase	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
CMS1_k127_2201390_2	411490.ANACAC_02726	1.009e-90	313.0	COG0246@1|root,COG0246@2|Bacteria,1TPZU@1239|Firmicutes,248J5@186801|Clostridia	186801|Clostridia	G	Mannitol dehydrogenase	mtlD	-	1.1.1.17	ko:K00009	ko00051,map00051	-	R02703	RC00085	ko00000,ko00001,ko01000	-	-	-	Mannitol_dh,Mannitol_dh_C
CMS1_k127_2201390_9	1463821.JOGR01000007_gene166	2.958e-21	99.0	COG0508@1|root,COG0508@2|Bacteria,2GMUV@201174|Actinobacteria,4EY1W@85014|Glycomycetales	201174|Actinobacteria	C	e3 binding domain	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
CMS1_k127_2213051_0	204669.Acid345_4052	3.776e-175	574.0	COG0204@1|root,COG0318@1|root,COG0477@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,COG2814@2|Bacteria,3Y4RT@57723|Acidobacteria	57723|Acidobacteria	IQ	Phosphate acyltransferases	-	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase,MFS_1
CMS1_k127_2216929_7	290398.Csal_2842	9.81e-30	129.0	COG0388@1|root,COG0388@2|Bacteria,1MXG5@1224|Proteobacteria,1RP7S@1236|Gammaproteobacteria,1XR8C@135619|Oceanospirillales	135619|Oceanospirillales	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
CMS1_k127_2216929_10	675635.Psed_1487	6.139e-16	87.0	COG3828@1|root,COG3828@2|Bacteria,2IKYF@201174|Actinobacteria,4E7FD@85010|Pseudonocardiales	201174|Actinobacteria	S	Trehalose utilisation	-	-	-	ko:K09992	-	-	-	-	ko00000	-	-	-	ThuA
CMS1_k127_2216929_9	391625.PPSIR1_03993	1.039e-17	98.0	COG0791@1|root,COG0791@2|Bacteria,1MU8A@1224|Proteobacteria,43C67@68525|delta/epsilon subdivisions,2X7GE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	NLP P60 protein	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60
CMS1_k127_2216929_8	402881.Plav_2672	5.598e-19	102.0	COG0674@1|root,COG0674@2|Bacteria,1QVAZ@1224|Proteobacteria,2TYHW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	pyruvate-flavodoxin oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2216929_2	1131269.AQVV01000048_gene2100	6.545e-148	490.0	COG0457@1|root,COG0457@2|Bacteria	1131269.AQVV01000048_gene2100|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2216929_5	439235.Dalk_2978	2.951e-120	390.0	COG1216@1|root,COG1216@2|Bacteria,1R50T@1224|Proteobacteria,42P74@68525|delta/epsilon subdivisions,2WK88@28221|Deltaproteobacteria,2MJIE@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_23
CMS1_k127_2216929_1	105559.Nwat_1144	1.311e-188	599.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RMFF@1236|Gammaproteobacteria,1WWGK@135613|Chromatiales	135613|Chromatiales	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim
CMS1_k127_2216929_4	880073.Calab_1318	8.078e-141	460.0	COG0508@1|root,COG0508@2|Bacteria,2NP69@2323|unclassified Bacteria	2|Bacteria	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	aceF	GO:0003674,GO:0003824,GO:0004742,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016407,GO:0016417,GO:0016418,GO:0016740,GO:0016746,GO:0016747,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030523,GO:0031405,GO:0031406,GO:0032787,GO:0032991,GO:0033293,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045254,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1902494,GO:1990204	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iETEC_1333.ETEC_0111,iSSON_1240.SSON_0123,iYL1228.KPN_00119	2-oxoacid_dh,Biotin_lipoyl,E3_binding
CMS1_k127_2216929_0	945713.IALB_2978	0.0	1373.0	COG2609@1|root,COG2609@2|Bacteria	2|Bacteria	C	pyruvate dehydrogenase (acetyl-transferring) activity	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
CMS1_k127_2216929_3	1090320.KB900606_gene188	5.413e-145	464.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,2TRHS@28211|Alphaproteobacteria,2K0VS@204457|Sphingomonadales	204457|Sphingomonadales	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS1_k127_2217035_0	234267.Acid_6992	2.329e-215	692.0	COG2183@1|root,COG2183@2|Bacteria,3Y2QM@57723|Acidobacteria	57723|Acidobacteria	K	SMART Resolvase, RNase H domain protein fold	-	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
CMS1_k127_2217035_9	96561.Dole_0398	6.627e-28	125.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red,HEAT_2,TetR_C_7,TetR_N
CMS1_k127_2217035_6	1123368.AUIS01000015_gene2636	6.938e-46	177.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,1RP1T@1236|Gammaproteobacteria,2NCI4@225057|Acidithiobacillales	225057|Acidithiobacillales	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
CMS1_k127_2217035_7	234267.Acid_4105	5.972e-45	183.0	COG0367@1|root,COG0367@2|Bacteria,3Y6CC@57723|Acidobacteria	57723|Acidobacteria	E	TIGRFAM asparagine synthase (glutamine-hydrolyzing)	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
CMS1_k127_2217035_4	235909.GK2577	9.583e-55	196.0	COG1490@1|root,COG1490@2|Bacteria,1V6GH@1239|Firmicutes,4HINN@91061|Bacilli,1WGCQ@129337|Geobacillus	91061|Bacilli	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
CMS1_k127_2217035_2	1382356.JQMP01000003_gene2139	1.341e-134	440.0	COG0686@1|root,COG0686@2|Bacteria,2G68X@200795|Chloroflexi,27YU4@189775|Thermomicrobia	189775|Thermomicrobia	C	Alanine dehydrogenase/PNT, N-terminal domain	-	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
CMS1_k127_2217035_10	644966.Tmar_0450	3.083e-21	107.0	COG2234@1|root,COG2234@2|Bacteria,1UZC9@1239|Firmicutes,24FE4@186801|Clostridia	186801|Clostridia	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
CMS1_k127_2217035_3	756272.Plabr_0148	2.016e-86	294.0	COG1082@1|root,COG1082@2|Bacteria,2IXNX@203682|Planctomycetes	203682|Planctomycetes	G	COG1082 Sugar phosphate	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
CMS1_k127_2217035_5	1198452.Jab_2c16710	1.122e-46	185.0	COG2199@1|root,COG2204@1|root,COG2204@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2W8YT@28216|Betaproteobacteria,476D8@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS,PAS_4,Response_reg
CMS1_k127_2217035_8	1499967.BAYZ01000028_gene1277	6.551e-28	117.0	COG1534@1|root,COG1534@2|Bacteria	2|Bacteria	J	preribosome binding	yhbY	GO:0000027,GO:0000028,GO:0000966,GO:0000967,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0034470,GO:0034471,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0042274,GO:0043021,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1990275	-	ko:K07574	-	-	-	-	ko00000,ko03009	-	-	-	CRS1_YhbY
CMS1_k127_2217035_1	344747.PM8797T_31143	2.017e-164	548.0	COG0591@1|root,COG0591@2|Bacteria	2|Bacteria	E	symporter activity	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	Kelch_1,Kelch_5,Kelch_6,SSF
CMS1_k127_222648_0	909663.KI867150_gene1436	1.311e-280	869.0	COG1155@1|root,COG1155@2|Bacteria,1MWRR@1224|Proteobacteria,42NKK@68525|delta/epsilon subdivisions,2WIQQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit	-	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
CMS1_k127_222648_1	909663.KI867150_gene1437	2.376e-207	648.0	COG1156@1|root,COG1156@2|Bacteria,1R4RB@1224|Proteobacteria,42PJC@68525|delta/epsilon subdivisions,2WJB9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	-	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
CMS1_k127_2236820_3	745411.B3C1_15919	4.314e-48	188.0	COG1680@1|root,COG1680@2|Bacteria,1RIU7@1224|Proteobacteria	1224|Proteobacteria	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS1_k127_2236820_0	1340493.JNIF01000003_gene2953	1.28e-112	378.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C,TAT_signal
CMS1_k127_2236820_2	697281.Mahau_1295	4.406e-51	193.0	COG3622@1|root,COG3622@2|Bacteria,1V3V8@1239|Firmicutes,25C7T@186801|Clostridia	186801|Clostridia	G	Belongs to the hyi family	-	-	5.3.1.22	ko:K01816	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
CMS1_k127_2236820_1	338963.Pcar_0608	1.719e-99	337.0	COG0502@1|root,COG0502@2|Bacteria,1MXK0@1224|Proteobacteria,42M3U@68525|delta/epsilon subdivisions,2WJQ6@28221|Deltaproteobacteria,43SKE@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Biotin and Thiamin Synthesis associated domain	thiH	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
CMS1_k127_2242912_1	1499967.BAYZ01000154_gene1524	3.42e-154	498.0	COG2230@1|root,COG2230@2|Bacteria,2NQ94@2323|unclassified Bacteria	2|Bacteria	M	Mycolic acid cyclopropane synthetase	cfa	-	2.1.1.317,2.1.1.79	ko:K00574,ko:K20238	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
CMS1_k127_2242912_0	1121904.ARBP01000042_gene4905	5.806e-174	572.0	COG3292@1|root,COG3292@2|Bacteria,4NF9I@976|Bacteroidetes,47XHD@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
CMS1_k127_2242912_2	1123508.JH636453_gene5800	1.854e-17	95.0	COG3391@1|root,COG3391@2|Bacteria,2J08H@203682|Planctomycetes	203682|Planctomycetes	J	Integrin alpha (beta-propellor repeats).	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
CMS1_k127_2242979_0	314278.NB231_00270	3.75e-06	57.0	COG2982@1|root,COG2982@2|Bacteria,1N0N6@1224|Proteobacteria,1SF4A@1236|Gammaproteobacteria,1X1M1@135613|Chromatiales	135613|Chromatiales	M	Protein involved in outer membrane biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2245196_0	1122931.AUAE01000028_gene155	4.495e-75	285.0	COG0823@1|root,COG0823@2|Bacteria,4NIGD@976|Bacteroidetes,2G2P7@200643|Bacteroidia	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2245399_0	1183438.GKIL_0837	7.754e-49	187.0	COG1525@1|root,COG1525@2|Bacteria,1G6RJ@1117|Cyanobacteria	1117|Cyanobacteria	L	nuclease	-	-	-	-	-	-	-	-	-	-	-	-	SNase
CMS1_k127_2245399_1	926562.Oweho_2402	1.257e-22	111.0	2EG06@1|root,339S8@2|Bacteria,4P1XT@976|Bacteroidetes,1I7TB@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2245450_3	1286171.EAL2_c07360	1.025e-40	163.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia,25UTK@186806|Eubacteriaceae	186801|Clostridia	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
CMS1_k127_2245450_1	1209989.TepiRe1_0530	1.869e-74	260.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,2480H@186801|Clostridia,42EWB@68295|Thermoanaerobacterales	186801|Clostridia	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	ACPS,Carb_kinase,YjeF_N
CMS1_k127_2245450_2	696369.KI912183_gene2680	1.611e-61	224.0	COG0611@1|root,COG0611@2|Bacteria,1V0SM@1239|Firmicutes,24J04@186801|Clostridia,262KV@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
CMS1_k127_2245450_0	886293.Sinac_7025	9.2e-90	299.0	COG1225@1|root,COG1225@2|Bacteria,2IYHT@203682|Planctomycetes	203682|Planctomycetes	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS1_k127_2247566_10	215803.DB30_0729	1.205e-10	75.0	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	ictB	-	-	ko:K02847,ko:K18814	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	9.B.67.1,9.B.67.4,9.B.67.5	-	-	Wzy_C
CMS1_k127_2247566_7	1121403.AUCV01000032_gene2910	3.822e-48	185.0	COG0615@1|root,COG0615@2|Bacteria,1N9T6@1224|Proteobacteria,42XKF@68525|delta/epsilon subdivisions,2WT6J@28221|Deltaproteobacteria,2MNG7@213118|Desulfobacterales	28221|Deltaproteobacteria	IM	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
CMS1_k127_2247566_9	550540.Fbal_0262	2.569e-36	156.0	COG2244@1|root,COG2244@2|Bacteria,1R9I0@1224|Proteobacteria,1RP3V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Membrane protein involved in the export of O-antigen and teichoic acid	wzxC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03328,ko:K16695	-	-	-	-	ko00000,ko02000	2.A.66.2,2.A.66.2.7	-	-	Polysacc_synt_3,Polysacc_synt_C
CMS1_k127_2247566_5	42256.RradSPS_1814	5.81e-58	220.0	COG5305@1|root,COG5305@2|Bacteria,2HPE5@201174|Actinobacteria,4CQS9@84995|Rubrobacteria	84995|Rubrobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS1_k127_2247566_0	589865.DaAHT2_2404	0.0	1836.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,1PKG6@1224|Proteobacteria,42MY4@68525|delta/epsilon subdivisions,2WJFI@28221|Deltaproteobacteria,2MIP0@213118|Desulfobacterales	28221|Deltaproteobacteria	I	BadF BadG BcrA BcrD	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
CMS1_k127_2247566_2	1079460.ATTQ01000016_gene5421	1.767e-102	364.0	COG0421@1|root,COG0421@2|Bacteria,1P220@1224|Proteobacteria,2U4F6@28211|Alphaproteobacteria,4BCVF@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
CMS1_k127_2247566_8	63737.Npun_F0403	2.361e-46	179.0	COG3209@1|root,COG3584@1|root,COG3209@2|Bacteria,COG3584@2|Bacteria,1GB8C@1117|Cyanobacteria	1117|Cyanobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2247566_1	485913.Krac_5709	7.131e-243	767.0	COG3533@1|root,COG3533@2|Bacteria,2G5YC@200795|Chloroflexi	200795|Chloroflexi	S	Beta-L-arabinofuranosidase, GH127	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_127
CMS1_k127_2247566_11	344747.PM8797T_02989	3.522e-09	71.0	COG0515@1|root,COG0515@2|Bacteria,2IX09@203682|Planctomycetes	203682|Planctomycetes	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF1080,FGE-sulfatase,LRR_6,Laminin_G_3,PEGA,Pkinase
CMS1_k127_2247566_4	316067.Geob_1615	1.56e-70	244.0	COG1853@1|root,COG1853@2|Bacteria,1RAIQ@1224|Proteobacteria,42QXX@68525|delta/epsilon subdivisions,2WMUR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
CMS1_k127_2247566_6	999419.HMPREF1077_03295	2.074e-49	192.0	COG0673@1|root,COG0673@2|Bacteria,4NHDS@976|Bacteroidetes,2FWWS@200643|Bacteroidia,22ZPV@171551|Porphyromonadaceae	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_2247566_3	1288963.ADIS_1779	2.443e-76	269.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2
CMS1_k127_2250273_1	760568.Desku_1284	5.724e-112	371.0	COG0044@1|root,COG0044@2|Bacteria,1TPQM@1239|Firmicutes,247V2@186801|Clostridia,260IR@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
CMS1_k127_2250273_0	1122939.ATUD01000001_gene577	2.751e-127	434.0	COG1520@1|root,COG1520@2|Bacteria,2H3K4@201174|Actinobacteria,4CRJK@84995|Rubrobacteria	84995|Rubrobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2250273_3	502025.Hoch_4593	6.795e-86	309.0	COG1716@1|root,COG2204@1|root,COG1716@2|Bacteria,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	frgC	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS1_k127_2250273_6	1123073.KB899241_gene2642	1.076e-46	192.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,1RSKR@1236|Gammaproteobacteria,1XCCR@135614|Xanthomonadales	135614|Xanthomonadales	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS1_k127_2250273_4	1408437.JNJN01000009_gene1186	5.711e-56	206.0	COG1561@1|root,COG1561@2|Bacteria,1TQHJ@1239|Firmicutes,24824@186801|Clostridia,25VXT@186806|Eubacteriaceae	186801|Clostridia	S	TIGR00255 family	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
CMS1_k127_2250273_5	1125863.JAFN01000001_gene1800	1.696e-55	203.0	COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,42R4H@68525|delta/epsilon subdivisions,2WNAD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
CMS1_k127_2250273_8	671143.DAMO_2577	0.0002323	46.0	COG1758@1|root,COG1758@2|Bacteria	2|Bacteria	K	DNA-directed 5'-3' RNA polymerase activity	rpoZ	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
CMS1_k127_2250273_2	1120985.AUMI01000015_gene1477	4.964e-109	366.0	COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,4H27H@909932|Negativicutes	909932|Negativicutes	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
CMS1_k127_2250273_7	1347368.HG964403_gene4830	4.498e-20	89.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,4HAEX@91061|Bacilli,1ZDBF@1386|Bacillus	91061|Bacilli	L	recombinase XerD	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
CMS1_k127_2255368_0	443143.GM18_2437	7.563e-17	93.0	COG4961@1|root,COG4961@2|Bacteria,1PUSH@1224|Proteobacteria,437D5@68525|delta/epsilon subdivisions,2XA18@28221|Deltaproteobacteria,43VQM@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	Tad
CMS1_k127_2258253_18	313628.LNTAR_11841	9.954e-08	62.0	COG1596@1|root,COG1596@2|Bacteria	2|Bacteria	M	polysaccharide export	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
CMS1_k127_2258253_14	204669.Acid345_0835	5.181e-28	132.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,3Y2V7@57723|Acidobacteria,2JIYH@204432|Acidobacteriia	204432|Acidobacteriia	D	G-rich domain on putative tyrosine kinase	-	-	-	ko:K16554	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	8.A.3.1	-	-	AAA_31,CbiA,GNVR,Wzz
CMS1_k127_2258253_20	1461694.ATO9_00355	0.000252	55.0	COG3118@1|root,COG3118@2|Bacteria,1MV0R@1224|Proteobacteria,2TS5X@28211|Alphaproteobacteria,2PCM8@252301|Oceanicola	28211|Alphaproteobacteria	O	Tetratricopeptide repeat	trxA2	-	-	ko:K03671,ko:K05838	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
CMS1_k127_2258253_21	1231392.OCGS_0869	0.000252	55.0	COG0457@1|root,COG0457@2|Bacteria,1MXMD@1224|Proteobacteria	1224|Proteobacteria	A	COG0457 FOG TPR repeat	prsT	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_8
CMS1_k127_2258253_10	1250278.JQNQ01000001_gene519	1.759e-53	205.0	COG1253@1|root,COG1253@2|Bacteria,4NE7C@976|Bacteroidetes,1HYD7@117743|Flavobacteriia	976|Bacteroidetes	S	COGs COG1253 Hemolysins and related protein containing CBS domains	-	-	-	-	-	-	-	-	-	-	-	-	CBS,DUF21
CMS1_k127_2258253_11	1128421.JAGA01000001_gene2144	3.061e-52	191.0	COG3127@1|root,COG3127@2|Bacteria	2|Bacteria	Q	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS1_k127_2258253_13	1128421.JAGA01000001_gene2145	2.592e-39	150.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	MA20_05735	-	-	-	-	-	-	-	-	-	-	-	HTH_34
CMS1_k127_2258253_8	1245469.S58_72670	4.576e-78	268.0	COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,2TU0N@28211|Alphaproteobacteria,3JT02@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	MA20_23565	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
CMS1_k127_2258253_17	1122925.KB895379_gene2173	3.836e-20	97.0	COG1595@1|root,COG1595@2|Bacteria,1V1S3@1239|Firmicutes,4HG2H@91061|Bacilli,26RSQ@186822|Paenibacillaceae	91061|Bacilli	K	Belongs to the sigma-70 factor family. ECF subfamily	ylaC	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_2258253_19	246197.MXAN_4148	3.033e-05	53.0	COG5662@1|root,COG5662@2|Bacteria	2|Bacteria	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
CMS1_k127_2258253_12	1415630.U771_02485	7.77e-49	190.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RQ86@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	general secretion pathway protein	gspF	-	-	ko:K02455	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
CMS1_k127_2258253_15	435908.IDSA_00095	3.136e-21	106.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RQMI@1236|Gammaproteobacteria,2QFCJ@267893|Idiomarinaceae	1236|Gammaproteobacteria	NU	Type II secretory pathway	mshG	-	-	ko:K02505,ko:K12278	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
CMS1_k127_2258253_6	1121468.AUBR01000002_gene701	2.868e-98	336.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,247KA@186801|Clostridia,42FCP@68295|Thermoanaerobacterales	186801|Clostridia	NU	PFAM Type II secretion system protein E	pilB	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
CMS1_k127_2258253_16	247490.KSU1_C1333	2.267e-20	104.0	COG4968@1|root,COG4968@2|Bacteria,2J519@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CMS1_k127_2258253_5	926569.ANT_15830	6.731e-102	340.0	COG1087@1|root,COG1087@2|Bacteria,2GA96@200795|Chloroflexi	200795|Chloroflexi	M	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
CMS1_k127_2258253_2	880072.Desac_1827	2.627e-109	390.0	COG2202@1|root,COG2204@1|root,COG3829@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2204@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MFW@68525|delta/epsilon subdivisions,2WJSJ@28221|Deltaproteobacteria,2MSID@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,dCache_1
CMS1_k127_2258253_3	589865.DaAHT2_0731	1.193e-106	359.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,42M4Y@68525|delta/epsilon subdivisions,2WKKD@28221|Deltaproteobacteria,2MIK0@213118|Desulfobacterales	28221|Deltaproteobacteria	T	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
CMS1_k127_2258253_7	864702.OsccyDRAFT_3642	5.563e-80	275.0	COG0338@1|root,COG0338@2|Bacteria,1G0BF@1117|Cyanobacteria,1H9B8@1150|Oscillatoriales	1117|Cyanobacteria	L	PFAM D12 class N6 adenine-specific DNA methyltransferase	dam	-	2.1.1.72	ko:K06223	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	-	-	-	MethyltransfD12
CMS1_k127_2258253_9	1254432.SCE1572_15255	3.899e-76	274.0	COG2203@1|root,COG2204@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2204@2|Bacteria,COG2206@2|Bacteria,1RAQS@1224|Proteobacteria,42MEJ@68525|delta/epsilon subdivisions,2X71A@28221|Deltaproteobacteria,2YUZY@29|Myxococcales	28221|Deltaproteobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HD,Response_reg
CMS1_k127_2258253_1	667014.Thein_1300	4.642e-170	545.0	COG0165@1|root,COG0165@2|Bacteria,2GGV2@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	Argininosuccinate lyase C-terminal	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
CMS1_k127_2258253_0	56780.SYN_02157	5.227e-175	556.0	COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,42N81@68525|delta/epsilon subdivisions,2WJB0@28221|Deltaproteobacteria,2MQ5Y@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
CMS1_k127_2258253_4	671143.DAMO_0075	1.826e-104	347.0	COG0078@1|root,COG0078@2|Bacteria,2NNWN@2323|unclassified Bacteria	2|Bacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
CMS1_k127_2266014_9	1142394.PSMK_01430	1.744e-49	186.0	COG2208@1|root,COG2208@2|Bacteria,2IYKI@203682|Planctomycetes	203682|Planctomycetes	KT	PFAM Stage II sporulation protein E (SpoIIE)	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	SpoIIE
CMS1_k127_2266014_1	1158338.JNLJ01000005_gene1621	2.15e-164	544.0	COG0542@1|root,COG0542@2|Bacteria,2G3N7@200783|Aquificae	200783|Aquificae	O	Belongs to the ClpA ClpB family	clpB	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
CMS1_k127_2266014_16	497964.CfE428DRAFT_2605	7.11e-08	58.0	2E99J@1|root,333HQ@2|Bacteria,46T77@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4032
CMS1_k127_2266014_17	202698.XP_007378344.1	0.0002841	48.0	2EBRF@1|root,2SHSB@2759|Eukaryota,3AII7@33154|Opisthokonta,3PB8V@4751|Fungi,3V43R@5204|Basidiomycota,224UP@155619|Agaricomycetes,3H3YV@355688|Agaricomycetes incertae sedis	4751|Fungi	S	protein Coprinopsis cinerea okayama7 130	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2266014_15	1365176.N186_06330	7.023e-15	86.0	COG0207@1|root,COG0294@1|root,arCOG05534@1|root,arCOG01978@2157|Archaea,arCOG03214@2157|Archaea,arCOG05534@2157|Archaea,2XS1E@28889|Crenarchaeota	28889|Crenarchaeota	H	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	-	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
CMS1_k127_2266014_7	869213.JCM21142_41474	1.753e-67	242.0	COG0180@1|root,COG0180@2|Bacteria,4NETX@976|Bacteroidetes,47JNM@768503|Cytophagia	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
CMS1_k127_2266014_0	518766.Rmar_1002	1.464e-192	613.0	COG1640@1|root,COG1640@2|Bacteria,4NF7Z@976|Bacteroidetes,1FIU5@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	4-alpha-glucanotransferase	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Alpha-amylase,Glyco_hydro_77
CMS1_k127_2266014_6	583355.Caka_0473	7.743e-68	239.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Calx-beta,DUF1080,F5_F8_type_C,PA14
CMS1_k127_2266014_13	243230.DR_2622	8.739e-22	107.0	COG0500@1|root,COG2226@2|Bacteria,1WKAF@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	Q	PFAM Methyltransferase type	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS1_k127_2266014_14	907348.TresaDRAFT_2627	1.133e-21	104.0	COG1713@1|root,COG1713@2|Bacteria,2J81K@203691|Spirochaetes	203691|Spirochaetes	H	HD superfamily hydrolase involved in NAD metabolism	-	-	-	-	-	-	-	-	-	-	-	-	HD
CMS1_k127_2266014_10	702437.HMPREF9432_00651	5.412e-40	156.0	COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,4H2AC@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
CMS1_k127_2266014_2	1283300.ATXB01000001_gene683	1.061e-149	485.0	COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,1RMAY@1236|Gammaproteobacteria,1XEVP@135618|Methylococcales	135618|Methylococcales	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS1_k127_2266014_4	1009370.ALO_08048	2.105e-103	348.0	COG0263@1|root,COG0263@2|Bacteria,1TPG6@1239|Firmicutes,4H29E@909932|Negativicutes	909932|Negativicutes	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
CMS1_k127_2266014_3	760568.Desku_0428	2.167e-120	400.0	COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,247SP@186801|Clostridia,25ZZB@186807|Peptococcaceae	186801|Clostridia	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
CMS1_k127_2266014_11	251229.Chro_3419	2.269e-33	130.0	COG0211@1|root,COG0211@2|Bacteria,1G7RW@1117|Cyanobacteria,3VK9B@52604|Pleurocapsales	1117|Cyanobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
CMS1_k127_2266014_12	86416.Clopa_2169	6.605e-24	106.0	COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,24MRS@186801|Clostridia,36JGP@31979|Clostridiaceae	186801|Clostridia	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
CMS1_k127_2266014_8	1094980.Mpsy_1281	6.861e-65	231.0	COG1712@1|root,arCOG00254@2157|Archaea,2XUNA@28890|Euryarchaeota,2NBJI@224756|Methanomicrobia	224756|Methanomicrobia	F	Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate	nadX	-	1.4.1.21	ko:K06989	ko00760,ko01100,map00760,map01100	-	R07407,R07410	RC02566	ko00000,ko00001,ko01000	-	-	-	DUF108,NAD_binding_3
CMS1_k127_2266014_5	504728.K649_09360	4.494e-99	329.0	COG2070@1|root,COG2070@2|Bacteria,1WMCT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Nitronate monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
CMS1_k127_2268302_2	500633.CLOHIR_01291	6.692e-221	710.0	COG0493@1|root,COG0543@1|root,COG0493@2|Bacteria,COG0543@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,25QHF@186804|Peptostreptococcaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	gltA	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	DHODB_Fe-S_bind,Fer4_20,NAD_binding_1,Pyr_redox_2
CMS1_k127_2268302_5	1123392.AQWL01000009_gene1115	8.976e-170	542.0	COG2046@1|root,COG2046@2|Bacteria,1MUQB@1224|Proteobacteria,2VR2T@28216|Betaproteobacteria	28216|Betaproteobacteria	H	PUA-like domain	sat	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-sulfurylase,PK,PUA_2
CMS1_k127_2268302_13	1121423.JONT01000001_gene2038	3.65e-67	237.0	COG1146@1|root,COG1146@2|Bacteria,1V59C@1239|Firmicutes,24J64@186801|Clostridia,261U8@186807|Peptococcaceae	186801|Clostridia	C	reductase beta subunit	-	-	1.8.99.2	ko:K00395	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	APS-reductase_C,Fer4_7,Fer4_9
CMS1_k127_2268302_0	706587.Desti_1443	0.0	1014.0	COG1053@1|root,COG1053@2|Bacteria,1NZBR@1224|Proteobacteria,42PSJ@68525|delta/epsilon subdivisions,2WJDD@28221|Deltaproteobacteria,2MQTR@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	FAD binding domain	aprA	-	1.8.99.2	ko:K00394	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2
CMS1_k127_2268302_15	335543.Sfum_1055	1.306e-32	129.0	COG0500@1|root,COG2226@2|Bacteria,1NHMR@1224|Proteobacteria,42XMB@68525|delta/epsilon subdivisions,2WT6Q@28221|Deltaproteobacteria,2MSC2@213462|Syntrophobacterales	28221|Deltaproteobacteria	Q	Ogr/Delta-like zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	Ogr_Delta
CMS1_k127_2268302_12	760568.Desku_1529	2.871e-70	247.0	COG0727@1|root,COG0727@2|Bacteria,1V2T2@1239|Firmicutes,24H4P@186801|Clostridia,262A6@186807|Peptococcaceae	186801|Clostridia	S	PFAM Uncharacterised protein family (UPF0153)	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
CMS1_k127_2268302_9	1121468.AUBR01000049_gene1631	1.644e-138	455.0	COG1148@1|root,COG1148@2|Bacteria,1TS8Y@1239|Firmicutes,24CXD@186801|Clostridia,42EZB@68295|Thermoanaerobacterales	186801|Clostridia	C	FAD dependent oxidoreductase	-	-	-	ko:K16885	-	-	-	-	ko00000	-	-	-	FAD_oxidored,Fer4,Fer4_10,Fer4_7,Fer4_9,NAD_binding_8,Pyr_redox_2
CMS1_k127_2268302_1	1121472.AQWN01000004_gene885	4.469e-256	812.0	COG1148@1|root,COG1908@1|root,COG1148@2|Bacteria,COG1908@2|Bacteria,1UT78@1239|Firmicutes,24A6H@186801|Clostridia,26171@186807|Peptococcaceae	186801|Clostridia	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	ko:K16886	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_9,FlpD,Pyr_redox_2
CMS1_k127_2268302_11	1379281.AVAG01000038_gene755	6.871e-101	342.0	COG1150@1|root,COG1150@2|Bacteria,1QUKA@1224|Proteobacteria,42MNE@68525|delta/epsilon subdivisions,2WIN3@28221|Deltaproteobacteria,2M85U@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	qmoC	-	-	ko:K16887	-	-	-	-	ko00000	-	-	-	Fer4_17,Fer4_8,Fer4_9,Nitrate_red_gam
CMS1_k127_2268302_10	489825.LYNGBM3L_61280	2.127e-128	427.0	COG2855@1|root,COG2855@2|Bacteria,1G0H4@1117|Cyanobacteria,1H7QS@1150|Oscillatoriales	1117|Cyanobacteria	S	Conserved hypothetical protein 698	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth698
CMS1_k127_2268302_7	1121430.JMLG01000003_gene583	1.053e-161	527.0	COG0446@1|root,COG0607@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,1TPWW@1239|Firmicutes,2484C@186801|Clostridia,2606T@186807|Peptococcaceae	186801|Clostridia	P	pyridine nucleotide-disulphide oxidoreductase dimerisation	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim,Rhodanese
CMS1_k127_2268302_4	331678.Cphamn1_1855	3.188e-173	559.0	COG0493@1|root,COG0493@2|Bacteria,1FDFY@1090|Chlorobi	1090|Chlorobi	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_20,Fer4_7,Fer4_9,Pyr_redox_2
CMS1_k127_2268302_3	1121423.JONT01000003_gene1087	1.025e-174	556.0	COG2221@1|root,COG2221@2|Bacteria,1TRP0@1239|Firmicutes,24A5T@186801|Clostridia,260BJ@186807|Peptococcaceae	186801|Clostridia	C	PFAM nitrite and sulphite reductase 4Fe-4S	dsrA	-	1.8.99.5	ko:K11180	ko00633,ko00920,ko01100,ko01120,map00633,map00920,map01100,map01120	M00596	R00295,R00861,R08035	RC00065,RC01760	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
CMS1_k127_2268302_6	1121428.DESHY_30086___1	2.663e-167	534.0	COG2221@1|root,COG2221@2|Bacteria,1TZD2@1239|Firmicutes,24DEF@186801|Clostridia,2610K@186807|Peptococcaceae	186801|Clostridia	C	TIGRFAM sulfite reductase, dissimilatory-type beta subunit	dsrB	-	1.8.99.5	ko:K11181	ko00633,ko00920,ko01100,ko01120,map00633,map00920,map01100,map01120	M00596	R00295,R00861,R08035	RC00065,RC01760	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,NIR_SIR,NIR_SIR_ferr
CMS1_k127_2268302_8	880072.Desac_1620	7.825e-153	496.0	COG1797@1|root,COG1797@2|Bacteria,1MV7Z@1224|Proteobacteria,42M8T@68525|delta/epsilon subdivisions,2WIXE@28221|Deltaproteobacteria,2MQYU@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source	cbiA	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	AAA_26,CbiA,GATase_3
CMS1_k127_2268302_14	706587.Desti_1118	5.899e-47	170.0	COG2920@1|root,COG2920@2|Bacteria,1RGVG@1224|Proteobacteria,42SN5@68525|delta/epsilon subdivisions,2WP28@28221|Deltaproteobacteria,2MS2U@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	DsrC like protein	dsrC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
CMS1_k127_2268302_17	335543.Sfum_1145	0.0005491	44.0	2CDHP@1|root,32RXU@2|Bacteria,1N1BP@1224|Proteobacteria,42TPT@68525|delta/epsilon subdivisions,2WQE6@28221|Deltaproteobacteria,2MRXY@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	RsbT co-antagonist protein rsbRD N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RsbRD_N
CMS1_k127_2291715_5	1122915.AUGY01000052_gene434	1.436e-24	106.0	COG0673@1|root,COG0673@2|Bacteria,1TPT5@1239|Firmicutes,4HAPJ@91061|Bacilli,26TP1@186822|Paenibacillaceae	91061|Bacilli	S	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_2291715_3	313628.LNTAR_21023	5.132e-99	335.0	COG0138@1|root,COG0138@2|Bacteria	2|Bacteria	F	bifunctional purine biosynthesis protein purh	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
CMS1_k127_2291715_2	1396141.BATP01000020_gene22	1.538e-124	429.0	COG1404@1|root,COG3469@1|root,COG1404@2|Bacteria,COG3469@2|Bacteria,46XKP@74201|Verrucomicrobia,2IW57@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
CMS1_k127_2291715_0	1210884.HG799462_gene7874	9.31e-194	619.0	COG2268@1|root,COG2268@2|Bacteria,2IYIX@203682|Planctomycetes	203682|Planctomycetes	S	prohibitin homologues	-	-	-	ko:K07192	ko04910,map04910	-	-	-	ko00000,ko00001,ko03036,ko04131,ko04147	-	-	-	Band_7
CMS1_k127_2291715_4	1210884.HG799462_gene7875	9.535e-25	113.0	29F7N@1|root,3025B@2|Bacteria,2J0ZE@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2291715_1	525897.Dbac_1384	8.936e-186	589.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MQI@68525|delta/epsilon subdivisions,2WN1S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Aminotransferase class I and II	-	-	2.6.1.2	ko:K00814	ko00220,ko00250,ko00710,ko01100,ko01120,ko01200,ko01210,ko01230,map00220,map00250,map00710,map01100,map01120,map01200,map01210,map01230	M00171	R00258	RC00006,RC00008	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS1_k127_229447_2	1161401.ASJA01000014_gene1044	2.858e-47	178.0	COG1629@1|root,COG4771@2|Bacteria,1R0WC@1224|Proteobacteria,2U1A6@28211|Alphaproteobacteria,43WF4@69657|Hyphomonadaceae	28211|Alphaproteobacteria	P	COG1629 Outer membrane receptor proteins, mostly Fe transport	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl_3,Plug,TonB_dep_Rec
CMS1_k127_229447_0	1035191.HMPREF0185_01935	8.875e-188	611.0	COG3540@1|root,COG3540@2|Bacteria,1MWAF@1224|Proteobacteria,2U33A@28211|Alphaproteobacteria,2KI61@204458|Caulobacterales	204458|Caulobacterales	P	PhoD-like phosphatase, N-terminal domain	-	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD,PhoD_N
CMS1_k127_229447_5	1297863.APJF01000022_gene4589	8.369e-08	57.0	COG0684@1|root,COG0684@2|Bacteria	2|Bacteria	H	ribonuclease inhibitor activity	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
CMS1_k127_229447_1	331869.BAL199_00165	3.998e-81	282.0	COG1262@1|root,COG4249@1|root,COG1262@2|Bacteria,COG4249@2|Bacteria,1MXFD@1224|Proteobacteria,2TRW5@28211|Alphaproteobacteria,4BQPK@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	M	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PG_binding_1,Peptidase_C14,SH3_3
CMS1_k127_229447_4	644107.SL1157_0518	8.768e-12	68.0	2DREZ@1|root,33BFB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_229447_3	1150469.RSPPHO_02107	7.392e-12	66.0	COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,2TR6F@28211|Alphaproteobacteria,2JR6A@204441|Rhodospirillales	204441|Rhodospirillales	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
CMS1_k127_2315510_3	1167006.UWK_00861	9.811e-14	77.0	COG3320@1|root,COG3320@2|Bacteria,1QSHC@1224|Proteobacteria,42W94@68525|delta/epsilon subdivisions,2WR9E@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_4
CMS1_k127_2315510_4	1157638.KB892172_gene3348	1.694e-09	61.0	COG0318@1|root,COG0318@2|Bacteria,2I8RE@201174|Actinobacteria	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
CMS1_k127_2315510_1	247490.KSU1_D0373	3.545e-68	241.0	COG0318@1|root,COG0318@2|Bacteria,2J4XH@203682|Planctomycetes	203682|Planctomycetes	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2315510_2	247490.KSU1_D0381	3.889e-30	130.0	COG2945@1|root,COG2945@2|Bacteria,2J37A@203682|Planctomycetes	203682|Planctomycetes	S	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2315510_0	926556.Echvi_4519	1.641e-121	400.0	COG3119@1|root,COG3119@2|Bacteria,4NHH7@976|Bacteroidetes	976|Bacteroidetes	P	Arylsulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CMS1_k127_2334855_1	1521187.JPIM01000038_gene3823	1.477e-15	83.0	COG2317@1|root,COG2317@2|Bacteria,2G7UQ@200795|Chloroflexi,37518@32061|Chloroflexia	32061|Chloroflexia	E	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues	-	-	3.4.17.19	ko:K01299	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M32
CMS1_k127_2334855_0	1122605.KB893625_gene1928	5.771e-91	328.0	2AF40@1|root,3152Q@2|Bacteria,4P1UF@976|Bacteroidetes,1IX0U@117747|Sphingobacteriia	976|Bacteroidetes	S	Heparinase II/III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III
CMS1_k127_2352830_1	886293.Sinac_0726	1.82e-139	457.0	COG0613@1|root,COG0613@2|Bacteria,2J1VB@203682|Planctomycetes	203682|Planctomycetes	S	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2352830_4	1167006.UWK_01361	5.188e-70	258.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,42MU2@68525|delta/epsilon subdivisions,2WMYH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family	-	-	-	-	-	-	-	-	-	-	-	-	OEP
CMS1_k127_2352830_3	502025.Hoch_6347	3.478e-71	256.0	COG0845@1|root,COG0845@2|Bacteria,1PEVY@1224|Proteobacteria,42NTH@68525|delta/epsilon subdivisions,2WJ8N@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3
CMS1_k127_2352830_0	1167006.UWK_01363	7.535e-294	935.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJN5@28221|Deltaproteobacteria,2MIEI@213118|Desulfobacterales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
CMS1_k127_2352830_2	234267.Acid_6247	3.049e-78	277.0	COG0673@1|root,COG0673@2|Bacteria,3Y39X@57723|Acidobacteria	57723|Acidobacteria	S	PFAM oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_2353341_1	518766.Rmar_2102	2.956e-107	369.0	COG0464@1|root,COG0464@2|Bacteria,4P1Y0@976|Bacteroidetes,1FIZT@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
CMS1_k127_2353341_0	472759.Nhal_1703	5.472e-157	500.0	COG1313@1|root,COG1313@2|Bacteria,1NZAK@1224|Proteobacteria	1224|Proteobacteria	C	radical SAM domain protein	-	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
CMS1_k127_2353341_2	545695.TREAZ_1194	7.233e-35	148.0	COG0407@1|root,COG0407@2|Bacteria	2|Bacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
CMS1_k127_2353341_3	472759.Nhal_1889	1.424e-08	59.0	COG0778@1|root,COG0778@2|Bacteria,1RJMP@1224|Proteobacteria,1T0ZH@1236|Gammaproteobacteria,1X0TI@135613|Chromatiales	135613|Chromatiales	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CMS1_k127_2358432_1	204669.Acid345_3229	2.025e-188	598.0	COG1158@1|root,COG1158@2|Bacteria,3Y2V3@57723|Acidobacteria,2JHRC@204432|Acidobacteriia	204432|Acidobacteriia	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
CMS1_k127_2358432_0	518766.Rmar_1349	4.438e-236	760.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,4NDVA@976|Bacteroidetes,1FJ68@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
CMS1_k127_2358432_3	671143.DAMO_1646	6.121e-85	296.0	COG0763@1|root,COG0763@2|Bacteria,2NP10@2323|unclassified Bacteria	2|Bacteria	I	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
CMS1_k127_2358432_2	671143.DAMO_1647	1.154e-88	302.0	COG0673@1|root,COG0673@2|Bacteria,2NNUQ@2323|unclassified Bacteria	2|Bacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	gnnA	-	-	ko:K09949	-	-	-	-	ko00000	-	-	iAF987.Gmet_2352	GFO_IDH_MocA
CMS1_k127_2358432_4	748449.Halha_2425	2.013e-70	252.0	COG1043@1|root,COG1043@2|Bacteria,1TQRI@1239|Firmicutes,24EGS@186801|Clostridia,3WAIK@53433|Halanaerobiales	186801|Clostridia	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
CMS1_k127_2358432_5	1121405.dsmv_0634	6.661e-40	162.0	COG0745@1|root,COG4191@1|root,COG0745@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42M6C@68525|delta/epsilon subdivisions,2WM3G@28221|Deltaproteobacteria,2MIRH@213118|Desulfobacterales	28221|Deltaproteobacteria	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
CMS1_k127_236883_0	1123008.KB905718_gene3614	8.807e-153	504.0	2C2C5@1|root,2ZBHC@2|Bacteria,4NU14@976|Bacteroidetes,2FQDI@200643|Bacteroidia,22YI2@171551|Porphyromonadaceae	976|Bacteroidetes	S	hydrolase activity, acting on glycosyl bonds	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_236883_2	435590.BVU_3866	1.381e-12	80.0	COG2407@1|root,COG2407@2|Bacteria,4P1BT@976|Bacteroidetes,2FMIE@200643|Bacteroidia,4AKFB@815|Bacteroidaceae	976|Bacteroidetes	G	COG2407 L-fucose isomerase and related	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_236883_1	717605.Theco_0773	2.171e-23	109.0	COG1609@1|root,COG1609@2|Bacteria,1TT82@1239|Firmicutes,4HFAP@91061|Bacilli,26RC9@186822|Paenibacillaceae	91061|Bacilli	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	GntR,Peripla_BP_1,Peripla_BP_3
CMS1_k127_2371312_2	1267533.KB906735_gene4670	1.393e-109	372.0	COG0383@1|root,COG0383@2|Bacteria	2|Bacteria	G	mannose metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
CMS1_k127_2371312_0	278957.ABEA03000005_gene4380	1.659e-163	525.0	COG0407@1|root,COG0407@2|Bacteria,46WW7@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
CMS1_k127_2371312_1	452637.Oter_2229	3.343e-154	508.0	COG2273@1|root,COG2273@2|Bacteria	2|Bacteria	G	xyloglucan:xyloglucosyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Glyco_hydro_16,Glyco_transf_25,Malectin,Ricin_B_lectin,Trans_reg_C,Trypsin,VCBS
CMS1_k127_2372029_1	344747.PM8797T_16735	3.128e-49	190.0	COG0501@1|root,COG0501@2|Bacteria,2IXM0@203682|Planctomycetes	203682|Planctomycetes	O	Zn-dependent protease with chaperone function	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
CMS1_k127_2372029_4	1121396.KB893025_gene3758	6.646e-23	102.0	2DTN3@1|root,33M10@2|Bacteria,1NPRB@1224|Proteobacteria	1224|Proteobacteria	S	BrnA antitoxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	BrnA_antitoxin
CMS1_k127_2372029_3	402777.KB235903_gene2201	1.84e-28	116.0	COG2929@1|root,COG2929@2|Bacteria,1G805@1117|Cyanobacteria,1HCPF@1150|Oscillatoriales	1117|Cyanobacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
CMS1_k127_2372029_2	1499967.BAYZ01000096_gene4319	8.46e-31	122.0	COG1724@1|root,COG1724@2|Bacteria	2|Bacteria	N	mRNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
CMS1_k127_2372029_5	631362.Thi970DRAFT_00649	7.847e-21	97.0	COG1598@1|root,COG1598@2|Bacteria	2|Bacteria	N	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
CMS1_k127_2372029_0	10224.XP_002732869.2	9.963e-107	363.0	COG3119@1|root,KOG3731@2759|Eukaryota,KOG3867@2759|Eukaryota,39S62@33154|Opisthokonta,3BDCF@33208|Metazoa,3CWGU@33213|Bilateria	33208|Metazoa	G	sulfuric ester hydrolase activity	ARSK	GO:0003674,GO:0003824,GO:0004065,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005788,GO:0008484,GO:0012505,GO:0016787,GO:0016788,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0070013	-	ko:K12376	-	-	-	-	ko00000,ko01000	-	-	-	DUF4976,Sulfatase
CMS1_k127_2376697_1	1123008.KB905709_gene654	3.708e-28	119.0	COG0226@1|root,COG0226@2|Bacteria,4NJGR@976|Bacteroidetes,2FMW1@200643|Bacteroidia,22YBA@171551|Porphyromonadaceae	976|Bacteroidetes	P	Phosphate ABC transporter substrate-binding protein	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
CMS1_k127_2376697_0	10224.XP_002732869.2	1.647e-120	406.0	COG3119@1|root,KOG3731@2759|Eukaryota,KOG3867@2759|Eukaryota,39S62@33154|Opisthokonta,3BDCF@33208|Metazoa,3CWGU@33213|Bilateria	33208|Metazoa	G	sulfuric ester hydrolase activity	ARSK	GO:0003674,GO:0003824,GO:0004065,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005788,GO:0008484,GO:0012505,GO:0016787,GO:0016788,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0070013	-	ko:K12376	-	-	-	-	ko00000,ko01000	-	-	-	DUF4976,Sulfatase
CMS1_k127_2376697_2	926569.ANT_06610	2.923e-19	92.0	COG0745@1|root,COG0745@2|Bacteria,2G986@200795|Chloroflexi	200795|Chloroflexi	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS1_k127_2377858_1	395493.BegalDRAFT_1405	3.359e-33	130.0	COG0741@1|root,COG0741@2|Bacteria	2|Bacteria	M	lytic transglycosylase activity	-	-	-	ko:K03194	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	-	-	-	CHAP,SLT
CMS1_k127_2377858_0	797210.Halxa_3791	1.414e-102	351.0	COG0673@1|root,arCOG01622@2157|Archaea,2XV4C@28890|Euryarchaeota,23T39@183963|Halobacteria	183963|Halobacteria	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_2377858_2	392500.Swoo_3062	1.605e-28	123.0	2F10C@1|root,33U1V@2|Bacteria,1NUUY@1224|Proteobacteria,1SNP3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2388985_1	1487921.DP68_15225	5.884e-19	100.0	COG1459@1|root,COG1459@2|Bacteria,1TQRZ@1239|Firmicutes,249FV@186801|Clostridia,36EIA@31979|Clostridiaceae	186801|Clostridia	NU	Type II secretion system	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
CMS1_k127_2388985_0	1313304.CALK_0488	2.711e-39	153.0	COG0566@1|root,COG0566@2|Bacteria	2|Bacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	spoU	-	2.1.1.185	ko:K03218,ko:K03437	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	SpoU_methylase
CMS1_k127_240690_4	177437.HRM2_48000	1.154e-16	94.0	COG0305@1|root,COG0305@2|Bacteria,1QWPB@1224|Proteobacteria	1224|Proteobacteria	L	DnaB-like helicase N terminal domain	-	-	3.6.4.12	ko:K02314,ko:K07505	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	AAA_25,DnaB
CMS1_k127_240690_2	396588.Tgr7_3139	5.393e-34	145.0	COG5295@1|root,COG5295@2|Bacteria,1N8QZ@1224|Proteobacteria	1224|Proteobacteria	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_240690_6	768706.Desor_1391	0.0007058	50.0	COG2247@1|root,COG3386@1|root,COG2247@2|Bacteria,COG3386@2|Bacteria,1VMQN@1239|Firmicutes	1239|Firmicutes	M	Putative cell wall binding repeat 2	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2
CMS1_k127_240690_0	1157490.EL26_21520	3.346e-84	290.0	COG4974@1|root,COG4974@2|Bacteria,1TQ3R@1239|Firmicutes,4HD6N@91061|Bacilli,278SR@186823|Alicyclobacillaceae	91061|Bacilli	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
CMS1_k127_240690_1	1408254.T458_06020	5.231e-40	154.0	COG2003@1|root,COG2003@2|Bacteria,1V38E@1239|Firmicutes,4HG4Q@91061|Bacilli,26X33@186822|Paenibacillaceae	91061|Bacilli	L	RadC-like JAB domain	-	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
CMS1_k127_240690_5	329726.AM1_6179	0.000154	50.0	COG4227@1|root,COG4227@2|Bacteria,1G5WT@1117|Cyanobacteria	1117|Cyanobacteria	L	Pfam:DUF955	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M78
CMS1_k127_2408898_0	886293.Sinac_0098	3.991e-169	556.0	COG3518@1|root,COG3518@2|Bacteria,2IYH2@203682|Planctomycetes	203682|Planctomycetes	S	anti-sigma factor antagonist activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2408898_2	530564.Psta_1339	3.056e-16	90.0	COG2165@1|root,COG2165@2|Bacteria,2IXWM@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CMS1_k127_2408898_1	196162.Noca_0471	1.096e-19	102.0	COG1609@1|root,COG1609@2|Bacteria,2GKFC@201174|Actinobacteria,4DPN2@85009|Propionibacteriales	201174|Actinobacteria	K	Periplasmic binding protein-like domain	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
CMS1_k127_2419577_5	272134.KB731324_gene3229	4.754e-107	364.0	COG5002@1|root,COG5002@2|Bacteria,1GQDS@1117|Cyanobacteria	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
CMS1_k127_2419577_4	1340493.JNIF01000003_gene2039	1.967e-125	413.0	2E9F7@1|root,333NI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2419577_11	237368.SCABRO_02775	7.44e-08	61.0	COG1361@1|root,COG3023@1|root,COG3064@1|root,COG3266@1|root,COG4412@1|root,COG1361@2|Bacteria,COG3023@2|Bacteria,COG3064@2|Bacteria,COG3266@2|Bacteria,COG4412@2|Bacteria,2J4CI@203682|Planctomycetes	203682|Planctomycetes	MV	Ami_2	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2
CMS1_k127_2419577_2	1303518.CCALI_02393	1.505e-158	519.0	COG5434@1|root,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBM-like,F5_F8_type_C,Pectate_lyase_3
CMS1_k127_2419577_9	314230.DSM3645_26609	1.295e-45	181.0	COG2010@1|root,COG2133@1|root,COG3828@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,COG3828@2|Bacteria,2IYH1@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,Cytochrom_C,Cytochrome_CBB3,Laminin_G_3,ThuA
CMS1_k127_2419577_7	314230.DSM3645_18581	2.361e-67	243.0	COG4409@1|root,COG4409@2|Bacteria,2J286@203682|Planctomycetes	203682|Planctomycetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
CMS1_k127_2419577_6	314230.DSM3645_29661	9.576e-83	288.0	COG4409@1|root,COG4409@2|Bacteria,2J1RF@203682|Planctomycetes	203682|Planctomycetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
CMS1_k127_2419577_3	107635.AZUO01000001_gene2177	1.378e-150	486.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,2TRTJ@28211|Alphaproteobacteria,36ZH1@31993|Methylocystaceae	28211|Alphaproteobacteria	P	Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
CMS1_k127_2419577_1	697282.Mettu_2032	7.414e-182	575.0	COG1409@1|root,COG1409@2|Bacteria,1MUQJ@1224|Proteobacteria,1S12Q@1236|Gammaproteobacteria,1XEF7@135618|Methylococcales	135618|Methylococcales	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
CMS1_k127_2419577_8	857087.Metme_0970	1.033e-50	183.0	COG3258@1|root,COG3258@2|Bacteria,1N1U2@1224|Proteobacteria,1SD42@1236|Gammaproteobacteria,1XFNF@135618|Methylococcales	135618|Methylococcales	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2419577_10	314230.DSM3645_26609	7.009e-39	169.0	COG2010@1|root,COG2133@1|root,COG3828@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,COG3828@2|Bacteria,2IYH1@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,Cytochrom_C,Cytochrome_CBB3,Laminin_G_3,ThuA
CMS1_k127_2419577_0	1158294.JOMI01000005_gene3164	5.065e-273	876.0	COG3250@1|root,COG3250@2|Bacteria,4NE7H@976|Bacteroidetes,2FQII@200643|Bacteroidia	976|Bacteroidetes	G	Glycosyl hydrolases family 2, TIM barrel domain	-	-	3.2.1.25	ko:K01192	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
CMS1_k127_2426008_3	156889.Mmc1_1916	2.211e-35	151.0	COG0457@1|root,COG1672@1|root,COG3118@1|root,COG0457@2|Bacteria,COG1672@2|Bacteria,COG3118@2|Bacteria	2|Bacteria	O	belongs to the thioredoxin family	bcsC	-	1.8.1.9,2.7.11.1	ko:K00384,ko:K02453,ko:K11912,ko:K14949,ko:K20543	ko00450,ko02025,ko03070,ko05111,ko05152,map00450,map02025,map03070,map05111,map05152	M00331	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko00002,ko01000,ko01001,ko02000,ko02044	1.B.55.3,3.A.15	-	-	BCSC_C,NfrA_C,Pkinase,PknG_TPR,PknG_rubred,TPR_16,TPR_19,TPR_8
CMS1_k127_2426008_1	1125973.JNLC01000018_gene2130	6.83e-83	286.0	COG0265@1|root,COG0265@2|Bacteria,1R6VW@1224|Proteobacteria,2UNAP@28211|Alphaproteobacteria,3K1U9@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2426008_2	1205908.AKXW01000045_gene3578	1.005e-35	150.0	2A45W@1|root,30SQX@2|Bacteria,1PC2Z@1224|Proteobacteria,1TIY1@1236|Gammaproteobacteria,1XZZG@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2426008_0	1303518.CCALI_00676	1.124e-194	622.0	COG3533@1|root,COG3533@2|Bacteria	2|Bacteria	S	Beta-L-arabinofuranosidase, GH127	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
CMS1_k127_2426767_1	344747.PM8797T_18384	1.633e-91	310.0	COG0673@1|root,COG0673@2|Bacteria,2IWRC@203682|Planctomycetes	203682|Planctomycetes	S	COGs COG0673 dehydrogenase and related protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_2426767_0	143224.JQMD01000002_gene250	4.792e-123	411.0	COG0823@1|root,COG0823@2|Bacteria,4NFRP@976|Bacteroidetes,1I626@117743|Flavobacteriia	976|Bacteroidetes	U	Protein of unknown function (DUF3748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3748,PD40
CMS1_k127_2426767_3	1117314.PCIT_05614	3.732e-23	113.0	COG5295@1|root,COG5295@2|Bacteria,1N8QZ@1224|Proteobacteria	1224|Proteobacteria	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2426767_2	396588.Tgr7_3139	1.478e-32	142.0	COG5295@1|root,COG5295@2|Bacteria,1N8QZ@1224|Proteobacteria	1224|Proteobacteria	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2435_3	1265503.KB905160_gene2526	3.507e-06	59.0	COG3595@1|root,COG3595@2|Bacteria,1NG89@1224|Proteobacteria,1SCZV@1236|Gammaproteobacteria,2Q846@267889|Colwelliaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
CMS1_k127_2435_2	861299.J421_0907	4.038e-29	126.0	COG1595@1|root,COG1595@2|Bacteria,1ZT2V@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_2435_0	639282.DEFDS_1110	1.298e-115	383.0	COG2805@1|root,COG2805@2|Bacteria,2GEWK@200930|Deferribacteres	200930|Deferribacteres	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
CMS1_k127_2435_1	1196323.ALKF01000168_gene537	1.88e-37	147.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,4HAD8@91061|Bacilli,26T5F@186822|Paenibacillaceae	91061|Bacilli	M	cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	iYO844.BSU15230	FAD_binding_4,MurB_C
CMS1_k127_2442317_1	1267535.KB906767_gene2913	1.389e-08	62.0	COG4974@1|root,COG4974@2|Bacteria,3Y73V@57723|Acidobacteria	57723|Acidobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
CMS1_k127_2442317_0	290512.Paes_2233	2.492e-55	209.0	COG1262@1|root,COG1262@2|Bacteria,1FEDD@1090|Chlorobi	1090|Chlorobi	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,TIR_2
CMS1_k127_2452795_3	195253.Syn6312_1483	1.017e-05	47.0	COG1598@1|root,COG1598@2|Bacteria,1G9W5@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2452795_1	111781.Lepto7376_2197	2.156e-51	188.0	COG0251@1|root,COG0251@2|Bacteria,1G71N@1117|Cyanobacteria	1117|Cyanobacteria	J	translation initiation inhibitor, yjgF family	-	-	4.2.99.21	ko:K04782	ko01053,ko01110,ko01130,map01053,map01110,map01130	-	R06602	RC01549,RC02148	ko00000,ko00001,ko01000	-	-	-	Ribonuc_L-PSP
CMS1_k127_2452795_0	1453498.LG45_03750	1.868e-147	471.0	COG1209@1|root,COG1209@2|Bacteria,4NE1U@976|Bacteroidetes,1HWWH@117743|Flavobacteriia,2NS8M@237|Flavobacterium	976|Bacteroidetes	M	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
CMS1_k127_2452795_2	1278309.KB907100_gene2058	7.303e-39	149.0	COG0500@1|root,COG2226@2|Bacteria,1MVSY@1224|Proteobacteria,1S24V@1236|Gammaproteobacteria,1XJBT@135619|Oceanospirillales	135619|Oceanospirillales	Q	Methionine biosynthesis protein MetW	metW	-	-	-	-	-	-	-	-	-	-	-	MetW
CMS1_k127_2469193_1	180332.JTGN01000015_gene1139	2.624e-63	229.0	COG3210@1|root,COG4733@1|root,COG5263@1|root,COG5492@1|root,COG3210@2|Bacteria,COG4733@2|Bacteria,COG5263@2|Bacteria,COG5492@2|Bacteria,1V36B@1239|Firmicutes,25B7T@186801|Clostridia	186801|Clostridia	U	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_3,FIVAR,LRR_5
CMS1_k127_2469193_2	1500304.JQKY01000002_gene3865	7.426e-05	52.0	COG0454@1|root,COG0456@2|Bacteria,1R4SN@1224|Proteobacteria,2U0VQ@28211|Alphaproteobacteria,4BBQR@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS1_k127_2469193_0	1408254.T458_00145	1.452e-91	327.0	COG2936@1|root,COG2936@2|Bacteria,1TT0H@1239|Firmicutes,4HC37@91061|Bacilli,26TMF@186822|Paenibacillaceae	91061|Bacilli	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
CMS1_k127_2472484_3	589865.DaAHT2_0649	4.366e-15	76.0	COG2203@1|root,COG2203@2|Bacteria	2|Bacteria	T	Gaf domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
CMS1_k127_2472484_1	290512.Paes_1607	1.18e-75	267.0	COG1283@1|root,COG1283@2|Bacteria,1FEHC@1090|Chlorobi	1090|Chlorobi	P	Na+/Pi-cotransporter	-	-	-	ko:K14683	-	-	-	-	ko00000,ko02000,ko04147	2.A.58.1	-	-	Na_Pi_cotrans
CMS1_k127_2472484_2	187272.Mlg_1738	1.122e-22	106.0	COG0704@1|root,COG0704@2|Bacteria,1NRGK@1224|Proteobacteria,1SMQP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	PhoU domain	-	-	-	-	-	-	-	-	-	-	-	-	PhoU
CMS1_k127_2474815_2	616991.JPOO01000001_gene2850	4.531e-39	150.0	COG3119@1|root,COG3119@2|Bacteria,4NF1X@976|Bacteroidetes,1HYYH@117743|Flavobacteriia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CMS1_k127_2474815_1	1232683.ADIMK_1296	1.58e-58	217.0	COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,1RMMB@1236|Gammaproteobacteria,464F3@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0022613,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0036094,GO:0042254,GO:0042274,GO:0043167,GO:0043168,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	iAF1260.b4161,iBWG_1329.BWG_3876,iECDH10B_1368.ECDH10B_4356,iECDH1ME8569_1439.ECDH1ME8569_4021,iEKO11_1354.EKO11_4148,iEcDH1_1363.EcDH1_3829,iEcolC_1368.EcolC_3849,iJO1366.b4161,iUMNK88_1353.UMNK88_5099,iY75_1357.Y75_RS21675	RsgA_GTPase
CMS1_k127_2474815_3	69014.TK0224	2.27e-11	73.0	COG0500@1|root,arCOG01780@2157|Archaea,2Y67G@28890|Euryarchaeota,2431U@183968|Thermococci	183968|Thermococci	Q	Hypothetical methyltransferase	-	-	-	ko:K17462	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00609	R10404	RC00003	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11
CMS1_k127_2474815_0	1219626.HMPREF1639_00700	1.931e-94	331.0	COG0751@1|root,COG0751@2|Bacteria,1TNZ7@1239|Firmicutes,248RS@186801|Clostridia,25R5C@186804|Peptostreptococcaceae	186801|Clostridia	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
CMS1_k127_2475910_0	1122915.AUGY01000034_gene957	2.27e-58	216.0	COG2971@1|root,COG2971@2|Bacteria,1V0YJ@1239|Firmicutes,4HBBR@91061|Bacilli,26QIG@186822|Paenibacillaceae	91061|Bacilli	G	BadF BadG BcrA BcrD type	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
CMS1_k127_2475910_1	1279009.ADICEAN_01377	0.0002953	53.0	2CG1Y@1|root,2Z9QX@2|Bacteria,4NJI6@976|Bacteroidetes,47PFJ@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
CMS1_k127_2489716_5	338963.Pcar_2628	2.433e-38	144.0	COG2070@1|root,COG2070@2|Bacteria,1QZ4T@1224|Proteobacteria,43CFR@68525|delta/epsilon subdivisions,2X7QT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Conserved region in glutamate synthase	-	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase
CMS1_k127_2489716_6	255470.cbdbA685	1.8e-36	148.0	COG3383@1|root,COG3383@2|Bacteria,2GAS8@200795|Chloroflexi,34D7W@301297|Dehalococcoidia	301297|Dehalococcoidia	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_4,Fer4
CMS1_k127_2489716_0	243164.DET0729	7.223e-236	744.0	COG1894@1|root,COG1894@2|Bacteria,2G5K9@200795|Chloroflexi,34D48@301297|Dehalococcoidia	301297|Dehalococcoidia	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
CMS1_k127_2489716_4	1047013.AQSP01000091_gene641	3.206e-41	157.0	COG1905@1|root,COG1905@2|Bacteria,2NPSB@2323|unclassified Bacteria	2|Bacteria	C	Thioredoxin-like [2Fe-2S] ferredoxin	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
CMS1_k127_2489716_2	56780.SYN_03243	6.506e-122	403.0	COG1693@1|root,COG1693@2|Bacteria,1RAC2@1224|Proteobacteria,42QW9@68525|delta/epsilon subdivisions,2WMZV@28221|Deltaproteobacteria,2MQWZ@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Ribonuclease R winged-helix domain	-	-	-	ko:K09720	-	-	-	-	ko00000,ko03000	-	-	-	DUF128,HTH_12
CMS1_k127_2489716_1	1499967.BAYZ01000016_gene6550	9.899e-163	527.0	COG2326@1|root,COG2326@2|Bacteria	2|Bacteria	S	polyphosphate kinase activity	pap	-	-	-	-	-	-	-	-	-	-	-	PPK2
CMS1_k127_2489716_7	1043493.BBLU01000002_gene1637	2.873e-20	100.0	COG0546@1|root,COG0546@2|Bacteria,2IETC@201174|Actinobacteria	201174|Actinobacteria	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
CMS1_k127_2489716_3	1121438.JNJA01000003_gene3016	8.735e-47	182.0	COG5000@1|root,COG5000@2|Bacteria,1NU7E@1224|Proteobacteria,42YZ2@68525|delta/epsilon subdivisions,2WTQ1@28221|Deltaproteobacteria,2MHCF@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	signal transduction histidine kinase	-	-	2.7.13.3	ko:K02668,ko:K07709	ko02020,map02020	M00499,M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_10,PAS_4,PAS_9,sCache_3_2
CMS1_k127_2489716_8	1123405.AUMM01000031_gene1452	2.157e-07	54.0	COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,4HA4R@91061|Bacilli,26NQQ@186821|Sporolactobacillaceae	91061|Bacilli	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
CMS1_k127_2497340_21	697281.Mahau_2214	3.395e-11	74.0	2DBSS@1|root,2ZATI@2|Bacteria,1V13H@1239|Firmicutes,24D92@186801|Clostridia,42J9A@68295|Thermoanaerobacterales	186801|Clostridia	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
CMS1_k127_2497340_12	880073.Calab_2472	1.793e-37	160.0	COG3225@1|root,COG3225@2|Bacteria,2NNVN@2323|unclassified Bacteria	2|Bacteria	N	ABC-type uncharacterized transport system	gldG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
CMS1_k127_2497340_15	1340493.JNIF01000003_gene2560	1.472e-33	140.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	yxlG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3,ABC_transp_aux
CMS1_k127_2497340_5	449447.MAE_20490	8.384e-90	306.0	COG1131@1|root,COG1131@2|Bacteria,1G11U@1117|Cyanobacteria	1117|Cyanobacteria	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_2497340_26	443144.GM21_0360	9.822e-05	47.0	COG2199@1|root,COG3706@2|Bacteria,1QWNG@1224|Proteobacteria,42SDQ@68525|delta/epsilon subdivisions,2WP1N@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,Response_reg
CMS1_k127_2497340_0	880073.Calab_0537	2.582e-242	758.0	COG0459@1|root,COG0459@2|Bacteria,2NNM6@2323|unclassified Bacteria	2|Bacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016465,GO:0018995,GO:0020003,GO:0023051,GO:0023056,GO:0030430,GO:0032991,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0051082,GO:0061077,GO:0065007,GO:0065010,GO:0101031,GO:1901222,GO:1901224,GO:1902531,GO:1902533,GO:1990220,GO:2000535	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
CMS1_k127_2497340_13	933262.AXAM01000031_gene3018	2.031e-36	142.0	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,42U7E@68525|delta/epsilon subdivisions,2WPZP@28221|Deltaproteobacteria,2MKH2@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
CMS1_k127_2497340_18	111781.Lepto7376_2075	5.411e-24	110.0	COG4446@1|root,COG4446@2|Bacteria	2|Bacteria	P	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1499
CMS1_k127_2497340_1	1173024.KI912148_gene3103	1.191e-143	474.0	COG0531@1|root,COG0531@2|Bacteria,1G2VF@1117|Cyanobacteria,1JHVU@1189|Stigonemataceae	1117|Cyanobacteria	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease,AA_permease_2
CMS1_k127_2497340_2	661478.OP10G_1344	2.179e-142	477.0	COG4030@1|root,COG4733@1|root,COG4030@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
CMS1_k127_2497340_20	655815.ZPR_3499	5.362e-17	87.0	COG1610@1|root,COG1610@2|Bacteria,4NQFI@976|Bacteroidetes,1I1X6@117743|Flavobacteriia	976|Bacteroidetes	S	YqeY-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
CMS1_k127_2497340_8	1131269.AQVV01000065_gene1812	1.927e-50	186.0	COG0431@1|root,COG0431@2|Bacteria	2|Bacteria	S	FMN reductase (NADPH) activity	ssuE	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006790,GO:0006805,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008752,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009111,GO:0009267,GO:0009308,GO:0009310,GO:0009410,GO:0009605,GO:0009970,GO:0009987,GO:0009991,GO:0010181,GO:0016043,GO:0016054,GO:0016491,GO:0016645,GO:0016646,GO:0019439,GO:0019694,GO:0019752,GO:0022607,GO:0031667,GO:0031668,GO:0031669,GO:0032553,GO:0032787,GO:0033554,GO:0034641,GO:0036094,GO:0042178,GO:0042221,GO:0042365,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0042594,GO:0043167,GO:0043168,GO:0043420,GO:0043421,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046218,GO:0046306,GO:0046395,GO:0046483,GO:0046700,GO:0048037,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051716,GO:0052873,GO:0055114,GO:0065003,GO:0070887,GO:0071466,GO:0071496,GO:0071704,GO:0071840,GO:0072329,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.5.1.38,1.5.1.45	ko:K00299,ko:K16902	ko00380,ko00740,ko00920,ko01100,map00380,map00740,map00920,map01100	-	R05706,R07210,R09517,R09520,R09748,R10206	RC00046,RC00126,RC01779,RC02556	ko00000,ko00001,ko01000	-	-	iAF1260.b0937,iB21_1397.B21_00948,iBWG_1329.BWG_0789,iE2348C_1286.E2348C_0930,iECBD_1354.ECBD_2658,iECB_1328.ECB_00941,iECDH10B_1368.ECDH10B_1007,iECDH1ME8569_1439.ECDH1ME8569_0888,iECD_1391.ECD_00941,iECIAI1_1343.ECIAI1_0978,iECO103_1326.ECO103_0982,iECW_1372.ECW_m1047,iEKO11_1354.EKO11_2893,iETEC_1333.ETEC_1005,iEcDH1_1363.EcDH1_2706,iEcE24377_1341.EcE24377A_1052,iEcHS_1320.EcHS_A1046,iEcolC_1368.EcolC_2659,iJO1366.b0937,iSB619.SA_RS01880,iSbBS512_1146.SbBS512_E2381,iUMNK88_1353.UMNK88_1092,iWFL_1372.ECW_m1047,iY75_1357.Y75_RS04870	FMN_red
CMS1_k127_2497340_16	448385.sce7318	6.702e-32	144.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1MVI9@1224|Proteobacteria,42NB4@68525|delta/epsilon subdivisions,2WK9E@28221|Deltaproteobacteria,2YTU8@29|Myxococcales	28221|Deltaproteobacteria	D	protein involved in exopolysaccharide biosynthesis	wzc2	-	-	ko:K16554	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	8.A.3.1	-	-	AAA_31,CbiA,GNVR,ParA,Wzz
CMS1_k127_2497340_17	706587.Desti_2917	2.407e-28	130.0	COG1596@1|root,COG1596@2|Bacteria,1R6M3@1224|Proteobacteria,42SBA@68525|delta/epsilon subdivisions,2WPHA@28221|Deltaproteobacteria,2MS2V@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PFAM Polysaccharide biosynthesis export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
CMS1_k127_2497340_10	1041930.Mtc_2010	5.302e-40	161.0	COG1208@1|root,arCOG00666@2157|Archaea,2XT8U@28890|Euryarchaeota,2N9G1@224756|Methanomicrobia	224756|Methanomicrobia	M	PFAM transferase hexapeptide repeat containing protein	-	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,NTP_transferase
CMS1_k127_2497340_4	357808.RoseRS_4078	1.818e-94	320.0	COG0451@1|root,COG0451@2|Bacteria,2G6ET@200795|Chloroflexi,375HU@32061|Chloroflexia	32061|Chloroflexia	M	short-chain dehydrogenase reductase SDR	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
CMS1_k127_2497340_19	1454004.AW11_02195	1.076e-23	110.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
CMS1_k127_2497340_3	760568.Desku_2097	1.357e-110	368.0	COG0438@1|root,COG0438@2|Bacteria,1TR0Y@1239|Firmicutes,24B5E@186801|Clostridia,265TC@186807|Peptococcaceae	186801|Clostridia	M	Domain of unknown function (DUF1972)	-	-	-	ko:K12996	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glyco_transf_4,Glycos_transf_1
CMS1_k127_2497340_7	479434.Sthe_0904	5.633e-62	227.0	COG0438@1|root,COG0438@2|Bacteria,2G5PS@200795|Chloroflexi,27XVU@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS1_k127_2497340_11	1457250.BBMO01000001_gene1504	8.293e-40	163.0	COG0438@1|root,arCOG01403@2157|Archaea,2XWAX@28890|Euryarchaeota,23TPP@183963|Halobacteria	183963|Halobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS1_k127_2497340_14	1123278.KB893533_gene138	3.313e-35	155.0	COG3693@1|root,COG3693@2|Bacteria,4NE5Z@976|Bacteroidetes,47Q9Y@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolase family 10	xynT	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	CBM_4_9,Glyco_hydro_10
CMS1_k127_2497340_23	1380390.JIAT01000011_gene2709	2.175e-06	60.0	COG3307@1|root,COG3307@2|Bacteria,2HPED@201174|Actinobacteria,4CQSH@84995|Rubrobacteria	84995|Rubrobacteria	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
CMS1_k127_2497340_22	247490.KSU1_C1618	9.483e-10	71.0	COG2244@1|root,COG2244@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
CMS1_k127_2497340_6	1120972.AUMH01000002_gene2768	5.885e-85	299.0	COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,4HCBG@91061|Bacilli,279A0@186823|Alicyclobacillaceae	91061|Bacilli	M	Bacterial sugar transferase	cpsE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K13012,ko:K19428	-	-	-	-	ko00000,ko01000,ko01005	-	-	-	Bac_transf
CMS1_k127_2497340_9	530564.Psta_4559	2.707e-50	192.0	COG0515@1|root,COG0693@1|root,COG3806@1|root,COG0515@2|Bacteria,COG0693@2|Bacteria,COG3806@2|Bacteria,2IYBG@203682|Planctomycetes	203682|Planctomycetes	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DJ-1_PfpI,PD40,Pkinase
CMS1_k127_2497340_24	1382304.JNIL01000001_gene10	6.986e-06	59.0	COG1664@1|root,COG1664@2|Bacteria	2|Bacteria	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
CMS1_k127_2497340_25	1089549.AZUQ01000001_gene519	1.043e-05	49.0	COG1595@1|root,COG1595@2|Bacteria,2HYZS@201174|Actinobacteria,4EYK8@85014|Glycomycetales	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_2497430_4	909663.KI867150_gene1436	2.152e-43	160.0	COG1155@1|root,COG1155@2|Bacteria,1MWRR@1224|Proteobacteria,42NKK@68525|delta/epsilon subdivisions,2WIQQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit	-	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
CMS1_k127_2497430_2	909663.KI867150_gene1434	2.716e-69	247.0	COG1527@1|root,COG1527@2|Bacteria	2|Bacteria	C	subunit (C	ntpC	-	-	ko:K02119	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	DUF2764,vATP-synt_AC39
CMS1_k127_2497430_5	909663.KI867150_gene1433	1.082e-40	157.0	COG1390@1|root,COG1390@2|Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpE	-	-	ko:K02121	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_E
CMS1_k127_2497430_3	909663.KI867150_gene1432	7.32e-54	196.0	COG0636@1|root,COG0636@2|Bacteria	2|Bacteria	C	ATP hydrolysis coupled proton transport	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042802,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110,ko:K02124	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157,M00159	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1,3.A.2.2,3.A.2.3	-	-	ATP-synt_C
CMS1_k127_2497430_0	909663.KI867150_gene1431	4.618e-216	691.0	COG1269@1|root,COG1269@2|Bacteria,1QGFB@1224|Proteobacteria,42UWC@68525|delta/epsilon subdivisions,2X5C3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM V-type ATPase 116 kDa	-	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	-
CMS1_k127_2497430_1	1379698.RBG1_1C00001G1531	3.374e-78	274.0	COG0123@1|root,COG0123@2|Bacteria,2NPB6@2323|unclassified Bacteria	2|Bacteria	BQ	Histone deacetylase domain	acuC	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
CMS1_k127_2497430_6	2423.NA23_0201785	3.614e-09	63.0	COG2252@1|root,COG2252@2|Bacteria,2GBWV@200918|Thermotogae	200918|Thermotogae	S	PFAM Xanthine uracil vitamin C permease	-	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
CMS1_k127_2503273_2	1210884.HG799464_gene10637	9.525e-86	292.0	COG0160@1|root,COG0160@2|Bacteria,2IYM7@203682|Planctomycetes	203682|Planctomycetes	E	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
CMS1_k127_2503273_4	1128421.JAGA01000002_gene1873	8.172e-25	109.0	COG1959@1|root,COG1959@2|Bacteria,2NPZX@2323|unclassified Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
CMS1_k127_2503273_0	314230.DSM3645_25172	0.0	1244.0	COG0209@1|root,COG0209@2|Bacteria,2IWU1@203682|Planctomycetes	203682|Planctomycetes	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
CMS1_k127_2503273_3	756272.Plabr_1727	5.521e-46	176.0	COG1943@1|root,COG1943@2|Bacteria,2J110@203682|Planctomycetes	203682|Planctomycetes	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
CMS1_k127_2503273_1	1156937.MFUM_140029	7.031e-186	586.0	COG0208@1|root,COG0208@2|Bacteria,46SMW@74201|Verrucomicrobia,37FX3@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	-	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
CMS1_k127_2508638_0	1396418.BATQ01000041_gene6263	1.507e-64	236.0	COG0641@1|root,COG0641@2|Bacteria,46TC0@74201|Verrucomicrobia	74201|Verrucomicrobia	C	radical SAM	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	-
CMS1_k127_2508638_5	1396418.BATQ01000041_gene6262	1.883e-08	65.0	2CCWI@1|root,32WTX@2|Bacteria,46TR3@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2508638_1	521011.Mpal_1783	3.353e-46	183.0	COG3291@1|root,arCOG02559@1|root,arCOG02508@2157|Archaea,arCOG02510@2157|Archaea,arCOG02559@2157|Archaea	2157|Archaea	P	by modhmm	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,NosD,PKD,SBBP
CMS1_k127_2508638_3	1123508.JH636449_gene7300	1.227e-32	134.0	COG1595@1|root,COG1595@2|Bacteria,2IZ91@203682|Planctomycetes	203682|Planctomycetes	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_2508638_2	1353531.AZNX01000005_gene3327	4.076e-46	175.0	COG4287@1|root,COG4287@2|Bacteria,1NP5V@1224|Proteobacteria	1224|Proteobacteria	O	PhoPQ-activated pathogenicity-related protein	pqaA	-	-	-	-	-	-	-	-	-	-	-	PhoPQ_related
CMS1_k127_2509373_1	1121920.AUAU01000017_gene1228	1.608e-49	181.0	COG1671@1|root,COG1671@2|Bacteria	2|Bacteria	S	Uncharacterized BCR, YaiI/YqxD family COG1671	yaiI	-	-	ko:K09768	-	-	-	-	ko00000	-	-	-	DUF188
CMS1_k127_2509373_0	1297570.MESS4_380017	5.836e-130	424.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_2509373_2	1123508.JH636443_gene4841	2.469e-32	129.0	COG3324@1|root,COG3324@2|Bacteria,2J4IN@203682|Planctomycetes	203682|Planctomycetes	S	Glyoxalase-like domain	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
CMS1_k127_2513722_4	1403819.BATR01000102_gene3384	9.874e-46	190.0	COG0657@1|root,COG0657@2|Bacteria,46VAH@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
CMS1_k127_2513722_2	313628.LNTAR_00920	4.86e-109	384.0	COG3669@1|root,COG3669@2|Bacteria	2|Bacteria	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,F5_F8_type_C
CMS1_k127_2513722_1	1094980.Mpsy_0865	1.258e-109	360.0	COG2013@1|root,arCOG01908@2157|Archaea,2XUJJ@28890|Euryarchaeota,2N9IN@224756|Methanomicrobia	224756|Methanomicrobia	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
CMS1_k127_2513722_0	270374.MELB17_21141	4.773e-139	454.0	COG1396@1|root,COG2856@1|root,COG1396@2|Bacteria,COG2856@2|Bacteria,1PFUN@1224|Proteobacteria,1RR40@1236|Gammaproteobacteria,46AVB@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M78
CMS1_k127_2513722_3	765912.Thimo_3457	8.446e-53	191.0	COG1487@1|root,COG1487@2|Bacteria,1RCQ1@1224|Proteobacteria,1S2N6@1236|Gammaproteobacteria,1X14B@135613|Chromatiales	135613|Chromatiales	S	Domain of unknown function (DUF4411)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4411
CMS1_k127_2513722_5	338963.Pcar_0446	1.073e-35	144.0	2CAZH@1|root,2Z7RU@2|Bacteria,1RBDC@1224|Proteobacteria,42SC7@68525|delta/epsilon subdivisions,2WP8S@28221|Deltaproteobacteria,43SJW@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family	frdC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
CMS1_k127_2513722_6	1288963.ADIS_3353	4.619e-09	57.0	COG1053@1|root,COG1053@2|Bacteria,4NFDU@976|Bacteroidetes,47JE5@768503|Cytophagia	976|Bacteroidetes	C	TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
CMS1_k127_2520883_0	1121904.ARBP01000042_gene4905	3.177e-132	447.0	COG3292@1|root,COG3292@2|Bacteria,4NF9I@976|Bacteroidetes,47XHD@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
CMS1_k127_2520883_3	698757.Pogu_1068	5.564e-18	95.0	COG0508@1|root,arCOG01706@2157|Archaea,2XQW4@28889|Crenarchaeota	28889|Crenarchaeota	C	2-oxoacid dehydrogenases acyltransferase (catalytic domain)	pdhC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
CMS1_k127_2520883_1	1449063.JMLS01000012_gene5524	7.336e-77	273.0	COG0673@1|root,COG0673@2|Bacteria,1TP83@1239|Firmicutes,4HC0R@91061|Bacilli,26R3U@186822|Paenibacillaceae	91061|Bacilli	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	1.1.1.18,1.1.1.369,1.1.1.371	ko:K00010,ko:K16044	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	-	R01183,R09951,R09954	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_2520883_2	1123252.ATZF01000003_gene3617	2.593e-33	144.0	COG0477@1|root,COG0477@2|Bacteria,1TTC8@1239|Firmicutes,4HAPZ@91061|Bacilli	91061|Bacilli	EGP	Major facilitator superfamily	yqgE	-	-	ko:K08222	-	-	-	-	ko00000,ko02000	2.A.1.33	-	-	MFS_1
CMS1_k127_2521353_0	204669.Acid345_2691	4.16e-40	166.0	COG0457@1|root,COG0741@1|root,COG1729@1|root,COG0457@2|Bacteria,COG0741@2|Bacteria,COG1729@2|Bacteria,3Y2UJ@57723|Acidobacteria,2JIUE@204432|Acidobacteriia	204432|Acidobacteriia	M	Transglycosylase SLT domain	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,TPR_16,YfiO
CMS1_k127_2522956_2	521674.Plim_0259	7.446e-08	61.0	COG1250@1|root,COG1250@2|Bacteria,2IYHM@203682|Planctomycetes	203682|Planctomycetes	I	3-hydroxyacyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2522956_0	596151.DesfrDRAFT_3317	4.23e-84	289.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,43B8B@68525|delta/epsilon subdivisions,2X6MP@28221|Deltaproteobacteria,2MH4M@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	glycyl-radical enzyme activating protein family	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4,Fer4_12,Radical_SAM
CMS1_k127_2522956_1	556261.HMPREF0240_03397	4.484e-48	184.0	COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,36EFE@31979|Clostridiaceae	186801|Clostridia	C	Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde	cutC	-	2.3.1.54,4.3.99.4	ko:K00656,ko:K20038	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
CMS1_k127_2531156_12	871963.Desdi_1828	3.363e-14	83.0	COG0860@1|root,COG2247@1|root,COG3103@1|root,COG0860@2|Bacteria,COG2247@2|Bacteria,COG3103@2|Bacteria,1UYPW@1239|Firmicutes,24BHU@186801|Clostridia,260BF@186807|Peptococcaceae	186801|Clostridia	M	Cell Wall	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3,Big_4,Big_5,CW_binding_2,SH3_3,SPOR
CMS1_k127_2531156_0	1232410.KI421424_gene1632	3.79e-148	487.0	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,42MAP@68525|delta/epsilon subdivisions,2WIYI@28221|Deltaproteobacteria,43SPT@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Sodium:sulfate symporter transmembrane region	sdcS	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
CMS1_k127_2531156_11	1210884.HG799463_gene9376	1.667e-16	93.0	COG0699@1|root,COG0699@2|Bacteria,2J0G9@203682|Planctomycetes	203682|Planctomycetes	S	50S ribosome-binding GTPase	-	-	-	-	-	-	-	-	-	-	-	-	MMR_HSR1
CMS1_k127_2531156_9	756272.Plabr_1763	3.18e-27	128.0	COG1159@1|root,COG1159@2|Bacteria,2J1ZD@203682|Planctomycetes	203682|Planctomycetes	S	50S ribosome-binding GTPase	-	-	-	-	-	-	-	-	-	-	-	-	MMR_HSR1
CMS1_k127_2531156_6	1254432.SCE1572_05510	7.698e-45	173.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_2531156_7	1333507.AUTQ01000170_gene323	8.313e-42	160.0	COG3350@1|root,COG3350@2|Bacteria,1N0GC@1224|Proteobacteria,1S7V6@1236|Gammaproteobacteria,2Q2HT@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	YHS domain protein	-	-	-	-	-	-	-	-	-	-	-	-	YHS
CMS1_k127_2531156_4	525904.Tter_0169	1.122e-67	245.0	COG0382@1|root,COG0382@2|Bacteria,2NNVJ@2323|unclassified Bacteria	2|Bacteria	H	UbiA prenyltransferase family	ubiA	-	-	-	-	-	-	-	-	-	-	-	UbiA
CMS1_k127_2531156_1	247490.KSU1_B0097	4.531e-131	432.0	COG0448@1|root,COG0448@2|Bacteria,2IWRQ@203682|Planctomycetes	203682|Planctomycetes	H	Belongs to the bacterial plant glucose-1-phosphate adenylyltransferase family	-	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
CMS1_k127_2531156_10	1120988.AXWV01000001_gene351	1.18e-16	91.0	COG0730@1|root,COG0730@2|Bacteria,1RIJB@1224|Proteobacteria,1S8IX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	membrane transporter protein	Z012_05305	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
CMS1_k127_2531156_13	1122222.AXWR01000002_gene2184	6.553e-10	71.0	COG0204@1|root,COG0204@2|Bacteria,1WJXG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	PFAM Phospholipid glycerol acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
CMS1_k127_2531156_3	1047013.AQSP01000084_gene768	5.381e-84	287.0	COG1801@1|root,COG1801@2|Bacteria,2NPDU@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
CMS1_k127_2531156_2	497964.CfE428DRAFT_3846	4.786e-95	330.0	COG4948@1|root,COG4948@2|Bacteria,46S7G@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Mandelate Racemase Muconate Lactonizing	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C
CMS1_k127_2531156_5	1174528.JH992898_gene1434	6.298e-46	171.0	COG2954@1|root,COG2954@2|Bacteria,1G5NQ@1117|Cyanobacteria	1117|Cyanobacteria	S	protein conserved in bacteria	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CYTH
CMS1_k127_2531156_8	933262.AXAM01000025_gene3411	1.958e-38	152.0	COG3481@1|root,COG3481@2|Bacteria,1NH0C@1224|Proteobacteria,42Q7X@68525|delta/epsilon subdivisions,2WJW2@28221|Deltaproteobacteria,2MICY@213118|Desulfobacterales	28221|Deltaproteobacteria	S	nucleic acid binding OB-fold tRNA helicase-type	yhaM	-	-	ko:K03698	-	-	-	-	ko00000,ko01000,ko03019	-	-	-	HD,tRNA_anti-codon
CMS1_k127_2532992_17	1303518.CCALI_02545	5.519e-24	109.0	COG5434@1|root,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_28,Pectate_lyase_3
CMS1_k127_2532992_18	1282356.H045_06500	2.352e-22	111.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,1RMKV@1236|Gammaproteobacteria,1YSZK@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease,AA_permease_2
CMS1_k127_2532992_15	1120951.AUBG01000002_gene1073	4.234e-34	141.0	COG0730@1|root,COG0730@2|Bacteria,4NIAF@976|Bacteroidetes,1HZ6Q@117743|Flavobacteriia	976|Bacteroidetes	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
CMS1_k127_2532992_5	697281.Mahau_2725	2.137e-94	320.0	COG0407@1|root,COG0407@2|Bacteria,1TR8Q@1239|Firmicutes,24B2U@186801|Clostridia,42IQ4@68295|Thermoanaerobacterales	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	2.1.1.246,4.1.1.37	ko:K01599,ko:K14080	ko00680,ko00860,ko01100,ko01110,ko01120,ko01200,map00680,map00860,map01100,map01110,map01120,map01200	M00121,M00356	R03197,R04972,R09098,R10000	RC00035,RC00872,RC01144,RC02440	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
CMS1_k127_2532992_3	224325.AF_1815	5.139e-111	374.0	COG4992@1|root,arCOG00914@2157|Archaea,2XTKV@28890|Euryarchaeota,24610@183980|Archaeoglobi	28890|Euryarchaeota	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	lysJ	GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	-	ko:K05830	ko00220,ko00300,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01130,map01210,map01230	M00031,M00763	R09778,R10932	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CMS1_k127_2532992_8	224325.AF_1815	5.713e-80	282.0	COG4992@1|root,arCOG00914@2157|Archaea,2XTKV@28890|Euryarchaeota,24610@183980|Archaeoglobi	28890|Euryarchaeota	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	lysJ	GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	-	ko:K05830	ko00220,ko00300,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01130,map01210,map01230	M00031,M00763	R09778,R10932	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CMS1_k127_2532992_12	926550.CLDAP_27070	4.074e-53	201.0	2BWNB@1|root,32WFI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2532992_14	638301.HMPREF0444_1298	5.839e-39	154.0	COG1216@1|root,COG2246@1|root,COG1216@2|Bacteria,COG2246@2|Bacteria,1UIHV@1239|Firmicutes,4ISID@91061|Bacilli	91061|Bacilli	M	glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,GtrA
CMS1_k127_2532992_11	1118054.CAGW01000062_gene2325	4.504e-65	238.0	COG0498@1|root,COG0498@2|Bacteria,1TP25@1239|Firmicutes,4HA1F@91061|Bacilli,26RAH@186822|Paenibacillaceae	91061|Bacilli	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	-	-	-	-	-	-	-	-	-	-	-	-	PALP
CMS1_k127_2532992_6	997346.HMPREF9374_2154	1.12e-93	325.0	COG1840@1|root,COG1840@2|Bacteria,1TQC3@1239|Firmicutes,4HABY@91061|Bacilli,27CM5@186824|Thermoactinomycetaceae	91061|Bacilli	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6
CMS1_k127_2532992_7	1329516.JPST01000003_gene1163	3.083e-80	274.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,4H9MS@91061|Bacilli,27CNS@186824|Thermoactinomycetaceae	91061|Bacilli	P	TOBE domain	-	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
CMS1_k127_2532992_9	56780.SYN_01003	5.437e-69	238.0	COG2110@1|root,COG2110@2|Bacteria,1RCWP@1224|Proteobacteria,42RVP@68525|delta/epsilon subdivisions,2WNCX@28221|Deltaproteobacteria,2MQI0@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Appr-1'-p processing enzyme	ymdB	-	-	-	-	-	-	-	-	-	-	-	Macro
CMS1_k127_2532992_4	1123277.KB893179_gene3190	1.144e-97	327.0	COG1082@1|root,COG1082@2|Bacteria,4NGKX@976|Bacteroidetes,47JP9@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS1_k127_2532992_19	247490.KSU1_C1333	7.516e-20	100.0	COG4968@1|root,COG4968@2|Bacteria,2J519@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CMS1_k127_2532992_16	118173.KB235914_gene3105	6.721e-33	137.0	COG0666@1|root,COG0666@2|Bacteria,1G0E1@1117|Cyanobacteria,1H7BV@1150|Oscillatoriales	1117|Cyanobacteria	S	COG0666 FOG Ankyrin repeat	ank	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5
CMS1_k127_2532992_20	886293.Sinac_0923	4.346e-07	54.0	COG1413@1|root,COG2010@1|root,COG2133@1|root,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,2IXPU@203682|Planctomycetes	203682|Planctomycetes	C	heme-binding domain, Pirellula Verrucomicrobium type	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
CMS1_k127_2532992_1	1007103.AFHW01000119_gene1258	1.037e-130	431.0	COG0174@1|root,COG0174@2|Bacteria,1UZA1@1239|Firmicutes,4HE5E@91061|Bacilli,272AF@186822|Paenibacillaceae	91061|Bacilli	E	Glutamine synthetase, catalytic domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C
CMS1_k127_2532992_10	1288.SXYLSMQ121_0114	1.372e-68	241.0	COG1028@1|root,COG1028@2|Bacteria,1TSWA@1239|Firmicutes,4HBHR@91061|Bacilli,4H1EG@90964|Staphylococcaceae	91061|Bacilli	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS1_k127_2532992_2	1210884.HG799464_gene10642	1.609e-119	398.0	COG2133@1|root,COG2133@2|Bacteria,2IWVG@203682|Planctomycetes	203682|Planctomycetes	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2532992_13	324602.Caur_1277	2.128e-49	181.0	2E65M@1|root,330UB@2|Bacteria,2G8DC@200795|Chloroflexi	200795|Chloroflexi	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
CMS1_k127_2532992_0	344747.PM8797T_06847	9.56e-140	466.0	COG0657@1|root,COG3458@1|root,COG0657@2|Bacteria,COG3458@2|Bacteria,2J1TC@203682|Planctomycetes	203682|Planctomycetes	Q	acetylesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_254242_0	658086.HMPREF0994_03992	7.593e-88	315.0	COG3525@1|root,COG3525@2|Bacteria	2|Bacteria	G	beta-N-acetylhexosaminidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4838,F5_F8_type_C,Glyco_hydro_67N
CMS1_k127_254242_1	1408445.JHXP01000026_gene2302	6.848e-38	154.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,1S5KR@1236|Gammaproteobacteria,1JGK2@118969|Legionellales	118969|Legionellales	M	Beta-eliminating lyase	-	-	2.6.1.109	ko:K19715	-	-	R11395	RC00160	ko00000,ko01000,ko01005	-	-	-	DegT_DnrJ_EryC1
CMS1_k127_2542544_1	1443665.JACA01000013_gene4207	1.395e-13	80.0	COG0265@1|root,COG0265@2|Bacteria,4PKT1@976|Bacteroidetes,1I89F@117743|Flavobacteriia,2YGTW@290174|Aquimarina	976|Bacteroidetes	O	Trypsin-like peptidase domain	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Trypsin_2,fn3
CMS1_k127_2542544_0	1303518.CCALI_01287	2.204e-286	899.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	pdhA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K00162,ko:K11381	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
CMS1_k127_254618_2	1121406.JAEX01000031_gene2559	2.706e-18	91.0	COG4373@1|root,COG4373@2|Bacteria,1R5BY@1224|Proteobacteria,42QK7@68525|delta/epsilon subdivisions,2WKWP@28221|Deltaproteobacteria,2MA1G@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Terminase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_6
CMS1_k127_254618_0	324057.Pjdr2_5307	1.709e-103	346.0	COG0667@1|root,COG0667@2|Bacteria,1TRS0@1239|Firmicutes,4HBX5@91061|Bacilli,26STF@186822|Paenibacillaceae	91061|Bacilli	C	Voltage-gated potassium channel	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS1_k127_254618_1	1122164.JHWF01000003_gene2083	8.727e-35	136.0	COG0582@1|root,COG0582@2|Bacteria,1MWBN@1224|Proteobacteria,1RPD0@1236|Gammaproteobacteria,1JDMK@118969|Legionellales	118969|Legionellales	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
CMS1_k127_2567045_10	247490.KSU1_C1333	1.197e-17	95.0	COG4968@1|root,COG4968@2|Bacteria,2J519@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CMS1_k127_2567045_2	1430331.EP10_16030	3.978e-126	427.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4HBVV@91061|Bacilli,1WEKC@129337|Geobacillus	91061|Bacilli	S	ABC transporter C-terminal domain	ydiF	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
CMS1_k127_2567045_8	517418.Ctha_1316	1.671e-36	149.0	COG4731@1|root,COG4731@2|Bacteria,1FFHA@1090|Chlorobi	1090|Chlorobi	S	Uncharacterized protein conserved in bacteria (DUF2147)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2147
CMS1_k127_2567045_12	661478.OP10G_1747	3.592e-08	66.0	COG1413@1|root,COG2211@1|root,COG1413@2|Bacteria,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	3.4.11.2	ko:K01256,ko:K16210	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002,ko02000	2.A.2.5	-	-	HEAT_2,MFS_1
CMS1_k127_2567045_9	439235.Dalk_1630	6.972e-24	104.0	COG1146@1|root,COG1146@2|Bacteria,1N0QV@1224|Proteobacteria,42U2Z@68525|delta/epsilon subdivisions,2WR58@28221|Deltaproteobacteria,2MM2N@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	1.2.7.3	ko:K00176	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Fer4_7
CMS1_k127_2567045_1	706587.Desti_0013	9.816e-135	442.0	COG0674@1|root,COG0674@2|Bacteria,1NBSJ@1224|Proteobacteria,42MS1@68525|delta/epsilon subdivisions,2WJ97@28221|Deltaproteobacteria,2MRFE@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	ferredoxin oxidoreductase, alpha subunit	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
CMS1_k127_2567045_5	706587.Desti_0012	2.236e-94	319.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,42MD3@68525|delta/epsilon subdivisions,2WJQ0@28221|Deltaproteobacteria,2MR5W@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	ferredoxin oxidoreductase beta subunit	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
CMS1_k127_2567045_7	204669.Acid345_1808	1.181e-46	175.0	COG1014@1|root,COG1014@2|Bacteria,3Y6SM@57723|Acidobacteria	57723|Acidobacteria	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	1.2.7.3	ko:K00177	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
CMS1_k127_2567045_6	572478.Vdis_2279	4.753e-73	264.0	COG1148@1|root,arCOG02235@2157|Archaea,arCOG02236@2157|Archaea,2XS2Y@28889|Crenarchaeota	28889|Crenarchaeota	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Fer4,FlpD,Pyr_redox_2
CMS1_k127_2567045_11	933262.AXAM01000013_gene1326	5.801e-11	67.0	COG0789@1|root,COG0789@2|Bacteria,1RGYB@1224|Proteobacteria,42V1F@68525|delta/epsilon subdivisions,2WR79@28221|Deltaproteobacteria,2MKW6@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
CMS1_k127_2567045_4	44689.DDB0231414	1.81e-108	359.0	COG0408@1|root,KOG1518@2759|Eukaryota,3XBII@554915|Amoebozoa	554915|Amoebozoa	H	Coproporphyrinogen III oxidase	-	GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983	1.3.3.3	ko:K00228	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03220	RC00884	ko00000,ko00001,ko00002,ko01000	-	-	-	Coprogen_oxidas
CMS1_k127_2567045_3	1177179.A11A3_02637	1.853e-124	421.0	COG0591@1|root,COG0591@2|Bacteria,1QUXM@1224|Proteobacteria,1T251@1236|Gammaproteobacteria,1XJTT@135619|Oceanospirillales	135619|Oceanospirillales	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
CMS1_k127_2567045_13	517418.Ctha_0845	6.405e-06	56.0	COG0823@1|root,COG5184@1|root,COG0823@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	ko:K13669	-	-	-	-	ko00000,ko01000,ko01003	-	GT87	-	Cadherin-like,GT87,PD40
CMS1_k127_2567045_0	700598.Niako_3601	7.956e-264	844.0	COG4409@1|root,COG4692@1|root,COG4409@2|Bacteria,COG4692@2|Bacteria,4PKSV@976|Bacteroidetes,1IQ81@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Bacterial alpha-L-rhamnosidase	-	-	3.2.1.40	ko:K05989	-	-	-	-	ko00000,ko01000	-	-	-	BNR_2,Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
CMS1_k127_25683_1	1379698.RBG1_1C00001G1649	5.39e-131	434.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,2NNYX@2323|unclassified Bacteria	2|Bacteria	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	fabZ	GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0019171	3.5.1.108,4.2.1.59	ko:K02372,ko:K02535,ko:K13599,ko:K16363	ko00061,ko00540,ko00780,ko01100,ko01212,ko02020,map00061,map00540,map00780,map01100,map01212,map02020	M00060,M00083,M00498,M00572	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965,R07764,R10117,R10121	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005,ko02022	-	-	-	FabA,LpxC
CMS1_k127_25683_3	1156937.MFUM_230022	2.996e-85	296.0	COG1044@1|root,COG1044@2|Bacteria,46SAD@74201|Verrucomicrobia,37GE9@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,LpxD
CMS1_k127_25683_7	1499967.BAYZ01000088_gene5092	1.029e-05	56.0	COG2825@1|root,COG2825@2|Bacteria	2|Bacteria	M	unfolded protein binding	ompH	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
CMS1_k127_25683_2	1499967.BAYZ01000088_gene5093	1.22e-105	371.0	COG4775@1|root,COG4775@2|Bacteria,2NNNW@2323|unclassified Bacteria	2|Bacteria	M	Surface antigen	bamA	GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
CMS1_k127_25683_0	370438.PTH_0283	2e-316	988.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,26059@186807|Peptococcaceae	186801|Clostridia	O	Belongs to the ClpA ClpB family	clpC	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
CMS1_k127_25683_4	760568.Desku_3184	1.701e-63	232.0	COG3869@1|root,COG3869@2|Bacteria,1TPBA@1239|Firmicutes,247SS@186801|Clostridia,260ST@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the specific phosphorylation of arginine residues in proteins	mcsB	-	2.7.14.1	ko:K19405	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	ATP-gua_Ptrans
CMS1_k127_25683_5	240302.BN982_04075	5.214e-24	109.0	COG3880@1|root,COG3880@2|Bacteria,1V6YM@1239|Firmicutes,4HH4R@91061|Bacilli,3NE86@45667|Halobacillus	91061|Bacilli	S	UvrB/uvrC motif	mcsA	GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170	-	ko:K19411	-	-	-	-	ko00000	-	-	-	UVR
CMS1_k127_25683_6	926550.CLDAP_34290	3.953e-11	72.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	ASH,Big_3_2,Cadherin-like,Calx-beta,DUF11,DUF4347,DUF4430,DUF915,FTP,HYR,I-set,PQQ_2,PT-HINT,Peptidase_M36,Pro-kuma_activ,RHS_repeat,VCBS
CMS1_k127_256942_0	237368.SCABRO_03851	7.059e-16	88.0	COG2165@1|root,COG2165@2|Bacteria,2J0Q6@203682|Planctomycetes	203682|Planctomycetes	U	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CMS1_k127_2580404_4	886293.Sinac_3948	1.734e-69	249.0	COG5434@1|root,COG5434@2|Bacteria,2IX4E@203682|Planctomycetes	203682|Planctomycetes	M	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,NosD,Pectate_lyase_3
CMS1_k127_2580404_7	1210884.HG799466_gene12802	0.0001032	55.0	COG3661@1|root,COG3661@2|Bacteria	2|Bacteria	G	alpha-glucuronidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_67N
CMS1_k127_2580404_5	324057.Pjdr2_4647	6.641e-30	138.0	COG1595@1|root,COG1595@2|Bacteria,1VRNX@1239|Firmicutes,4HVBW@91061|Bacilli,26TMQ@186822|Paenibacillaceae	91061|Bacilli	K	GxGYxYP putative glycoside hydrolase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	GxGYxYP_C,GxGYxYP_N
CMS1_k127_2580404_3	595460.RRSWK_04701	1.09e-82	280.0	COG3828@1|root,COG3828@2|Bacteria	2|Bacteria	N	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CMS1_k127_2580404_2	886293.Sinac_2800	1.384e-84	293.0	COG4409@1|root,COG4409@2|Bacteria,2IX8T@203682|Planctomycetes	203682|Planctomycetes	G	BNR repeat-like domain	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2
CMS1_k127_2580404_0	595460.RRSWK_04700	6.533e-206	651.0	COG0673@1|root,COG0673@2|Bacteria,2IXRR@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_2580404_6	1089553.Tph_c09110	5.97e-08	65.0	2CJTW@1|root,33NBH@2|Bacteria,1VM99@1239|Firmicutes,24UVS@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2580404_1	1089553.Tph_c09100	2.599e-100	346.0	COG0407@1|root,COG0407@2|Bacteria,1TRJG@1239|Firmicutes,24B34@186801|Clostridia,42G9W@68295|Thermoanaerobacterales	186801|Clostridia	H	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
CMS1_k127_2581662_23	247490.KSU1_C1333	2.102e-17	94.0	COG4968@1|root,COG4968@2|Bacteria,2J519@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CMS1_k127_2581662_10	880073.Calab_2957	1.656e-73	261.0	COG0438@1|root,COG0438@2|Bacteria,2NPA0@2323|unclassified Bacteria	2|Bacteria	M	glycosyl transferase group 1	-	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
CMS1_k127_2581662_18	349521.HCH_01055	7.04e-40	163.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,1S34W@1236|Gammaproteobacteria,1XJ0B@135619|Oceanospirillales	135619|Oceanospirillales	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS1_k127_2581662_20	643648.Slip_1776	6.864e-35	144.0	COG1639@1|root,COG1639@2|Bacteria,1TPRT@1239|Firmicutes,249CG@186801|Clostridia,42KAI@68298|Syntrophomonadaceae	186801|Clostridia	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD,Response_reg
CMS1_k127_2581662_15	247490.KSU1_D0140	3.739e-57	209.0	COG0589@1|root,COG0589@2|Bacteria,2J11D@203682|Planctomycetes	203682|Planctomycetes	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS1_k127_2581662_12	1125971.ASJB01000043_gene3187	9.161e-68	251.0	COG3379@1|root,COG3379@2|Bacteria,2GVVM@201174|Actinobacteria	201174|Actinobacteria	S	PFAM type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
CMS1_k127_2581662_21	1041930.Mtc_0609	8.676e-34	143.0	COG1216@1|root,arCOG01383@2157|Archaea,2XW51@28890|Euryarchaeota,2N9HF@224756|Methanomicrobia	224756|Methanomicrobia	M	Glycosyl transferase family group 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
CMS1_k127_2581662_11	1123060.JONP01000008_gene4511	3.232e-69	240.0	COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,2TTVV@28211|Alphaproteobacteria,2JPDI@204441|Rhodospirillales	204441|Rhodospirillales	E	imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
CMS1_k127_2581662_14	1089553.Tph_c09580	1.024e-58	211.0	COG0639@1|root,COG0639@2|Bacteria,1UYWK@1239|Firmicutes,25DVG@186801|Clostridia,42IP1@68295|Thermoanaerobacterales	186801|Clostridia	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
CMS1_k127_2581662_27	103733.JNYO01000025_gene8900	1.036e-08	67.0	COG0438@1|root,COG0438@2|Bacteria,2GK8D@201174|Actinobacteria,4E570@85010|Pseudonocardiales	201174|Actinobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CMS1_k127_2581662_13	96561.Dole_1367	3.878e-62	240.0	COG0515@1|root,COG4252@1|root,COG0515@2|Bacteria,COG4252@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2MHTH@213118|Desulfobacterales	28221|Deltaproteobacteria	KLT	PFAM Protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	CHASE2,Pkinase
CMS1_k127_2581662_22	338966.Ppro_2261	3.391e-33	134.0	COG0802@1|root,COG0802@2|Bacteria,1RGYU@1224|Proteobacteria,42VU4@68525|delta/epsilon subdivisions,2WQBA@28221|Deltaproteobacteria,43V70@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	yjeE	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
CMS1_k127_2581662_2	1121468.AUBR01000034_gene1373	5.767e-133	439.0	COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,248G1@186801|Clostridia,42F2U@68295|Thermoanaerobacterales	186801|Clostridia	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1,HHH_3
CMS1_k127_2581662_9	264732.Moth_0626	2.465e-86	298.0	COG0327@1|root,COG0327@2|Bacteria,1TQ27@1239|Firmicutes,248Q2@186801|Clostridia,42ESG@68295|Thermoanaerobacterales	186801|Clostridia	C	Belongs to the GTP cyclohydrolase I type 2 NIF3 family	-	-	-	-	-	-	-	-	-	-	-	-	NIF3
CMS1_k127_2581662_17	880073.Calab_0988	1.992e-45	175.0	COG1355@1|root,COG2078@1|root,COG1355@2|Bacteria,COG2078@2|Bacteria,2NPAA@2323|unclassified Bacteria	2|Bacteria	S	AMMECR1	-	-	-	ko:K06990,ko:K09141	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,Memo
CMS1_k127_2581662_16	504472.Slin_5613	4.742e-55	201.0	COG2802@1|root,COG2802@2|Bacteria,4NEJU@976|Bacteroidetes,47NJ0@768503|Cytophagia	976|Bacteroidetes	S	Peptidase S16, lon domain protein	-	-	3.4.21.53	ko:K01338,ko:K07157	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	LON_substr_bdg
CMS1_k127_2581662_25	679190.HMPREF0650_1725	4.535e-14	79.0	COG2096@1|root,COG2096@2|Bacteria,4NFHQ@976|Bacteroidetes,2FQJ0@200643|Bacteroidia	976|Bacteroidetes	S	ATP cob(I)alamin adenosyltransferase	cobO	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
CMS1_k127_2581662_7	596324.TREVI0001_1259	3.444e-95	331.0	COG0708@1|root,COG0708@2|Bacteria,2J62E@203691|Spirochaetes	203691|Spirochaetes	L	exodeoxyribonuclease III	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
CMS1_k127_2581662_19	886293.Sinac_5315	1.014e-37	157.0	COG0682@1|root,COG0682@2|Bacteria,2IZQ2@203682|Planctomycetes	203682|Planctomycetes	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT,PDZ
CMS1_k127_2581662_0	207559.Dde_1059	1.447e-158	512.0	COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,42MK9@68525|delta/epsilon subdivisions,2WJ1C@28221|Deltaproteobacteria,2M8GR@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	SMART Nucleotide binding protein, PINc	phoH1	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
CMS1_k127_2581662_8	404589.Anae109_2774	4.396e-94	320.0	COG0604@1|root,COG0604@2|Bacteria,1MXUX@1224|Proteobacteria,42UGV@68525|delta/epsilon subdivisions,2WR1G@28221|Deltaproteobacteria,2YUDE@29|Myxococcales	28221|Deltaproteobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_2581662_3	1301098.PKB_3068	1.311e-118	410.0	COG1680@1|root,COG3876@1|root,COG1680@2|Bacteria,COG3876@2|Bacteria,1MVPR@1224|Proteobacteria,1RRTD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	estB	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS1_k127_2581662_26	247634.GPB2148_651	4.023e-12	77.0	COG0824@1|root,COG0824@2|Bacteria,1RI3X@1224|Proteobacteria,1SAHQ@1236|Gammaproteobacteria,1J6MR@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	thioesterase	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2,Acyl-ACP_TE
CMS1_k127_2581662_24	519989.ECTPHS_07636	2.003e-14	84.0	COG0824@1|root,COG0824@2|Bacteria,1RI3X@1224|Proteobacteria,1SAHQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Thioesterase	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2,Acyl-ACP_TE
CMS1_k127_2581662_5	913325.N799_00545	1.632e-106	359.0	COG1960@1|root,COG1960@2|Bacteria,1MUK0@1224|Proteobacteria,1RNBX@1236|Gammaproteobacteria,1X45S@135614|Xanthomonadales	135614|Xanthomonadales	I	Acyl-CoA dehydrogenase	gcdH	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS1_k127_2581662_1	335543.Sfum_0296	8.555e-157	511.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,42M1X@68525|delta/epsilon subdivisions,2WJA2@28221|Deltaproteobacteria,2MQ8Y@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Thiamine pyrophosphate enzyme, central	-	-	2.2.1.6,2.3.3.15	ko:K01652,ko:K03852	ko00290,ko00430,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00430,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R05651,R08648	RC00027,RC00106,RC01192,RC02744,RC02893,RC02903,RC02909	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS1_k127_2581662_6	1123242.JH636435_gene2917	3.343e-95	339.0	COG0457@1|root,COG3119@1|root,COG0457@2|Bacteria,COG3119@2|Bacteria,2J3IX@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,TPR_16,TPR_19,TPR_2
CMS1_k127_2581662_4	1227349.C170_23115	5.334e-110	369.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,4HDN8@91061|Bacilli,275I6@186822|Paenibacillaceae	91061|Bacilli	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
CMS1_k127_2586219_0	471854.Dfer_1237	1.58e-48	178.0	COG0673@1|root,COG0673@2|Bacteria,4NDYI@976|Bacteroidetes,47NPG@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_2586219_2	1267535.KB906767_gene3903	8.488e-12	76.0	2E1AY@1|root,32WQW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2586219_1	526225.Gobs_3495	2.83e-24	113.0	2DP71@1|root,330U0@2|Bacteria,2H00A@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF2971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2971
CMS1_k127_2593854_7	1265505.ATUG01000003_gene895	1.452e-114	380.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,42NC3@68525|delta/epsilon subdivisions,2WIJJ@28221|Deltaproteobacteria,2MJ98@213118|Desulfobacterales	28221|Deltaproteobacteria	V	ABC-2 family transporter protein	ybhR	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
CMS1_k127_2593854_3	1265505.ATUG01000003_gene896	3.336e-149	481.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,42P7V@68525|delta/epsilon subdivisions,2WJQA@28221|Deltaproteobacteria,2MJ2Q@213118|Desulfobacterales	28221|Deltaproteobacteria	V	ABC-2 family transporter protein	ybhS	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
CMS1_k127_2593854_0	439235.Dalk_2025	3.467e-258	812.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42MV1@68525|delta/epsilon subdivisions,2WK9W@28221|Deltaproteobacteria,2MIZ9@213118|Desulfobacterales	28221|Deltaproteobacteria	V	PFAM ABC transporter	ybhF-C	-	-	ko:K01990,ko:K09695	ko02010,map02010	M00252,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.102	-	-	ABC_tran,DUF4162
CMS1_k127_2593854_10	1265505.ATUG01000003_gene898	5.972e-96	328.0	COG0845@1|root,COG0845@2|Bacteria,1MUG6@1224|Proteobacteria,42R8A@68525|delta/epsilon subdivisions,2WM6Z@28221|Deltaproteobacteria,2MJGT@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Biotin-lipoyl like	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23
CMS1_k127_2593854_20	880072.Desac_1709	4.369e-52	190.0	COG1309@1|root,COG1309@2|Bacteria,1ND26@1224|Proteobacteria,43EW9@68525|delta/epsilon subdivisions,2X29Y@28221|Deltaproteobacteria,2MSD6@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	YsiA-like protein, C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_4
CMS1_k127_2593854_9	1121445.ATUZ01000011_gene559	8.66e-98	327.0	COG0500@1|root,COG2226@2|Bacteria,1MVXN@1224|Proteobacteria,42PQM@68525|delta/epsilon subdivisions,2WJIF@28221|Deltaproteobacteria,2MGE4@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
CMS1_k127_2593854_26	706587.Desti_5389	3.43e-28	119.0	COG0640@1|root,COG0640@2|Bacteria,1MZT1@1224|Proteobacteria,42V3T@68525|delta/epsilon subdivisions,2WS3M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	regulatory protein, arsR	-	-	-	ko:K03892,ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
CMS1_k127_2593854_17	1303518.CCALI_01110	8.372e-65	241.0	COG0483@1|root,COG0483@2|Bacteria	2|Bacteria	G	inositol monophosphate 1-phosphatase activity	suhB	-	3.1.3.25,3.1.3.7	ko:K01082,ko:K01092	ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070	M00131	R00188,R00508,R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	Inositol_P
CMS1_k127_2593854_15	1122919.KB905551_gene1682	2.052e-67	244.0	COG3828@1|root,COG3828@2|Bacteria	2|Bacteria	N	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
CMS1_k127_2593854_5	1131269.AQVV01000048_gene2100	1.624e-142	474.0	COG0457@1|root,COG0457@2|Bacteria	1131269.AQVV01000048_gene2100|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2593854_11	1267535.KB906767_gene2182	6.965e-93	314.0	COG0657@1|root,COG0657@2|Bacteria,3Y2TC@57723|Acidobacteria,2JIM8@204432|Acidobacteriia	204432|Acidobacteriia	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
CMS1_k127_2593854_29	1173264.KI913949_gene3688	7.914e-21	103.0	COG0457@1|root,COG2909@1|root,COG0457@2|Bacteria,COG2909@2|Bacteria,1G20P@1117|Cyanobacteria,1H8AZ@1150|Oscillatoriales	1117|Cyanobacteria	L	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_2,TPR_8
CMS1_k127_2593854_14	1191523.MROS_1971	4.337e-72	244.0	COG0432@1|root,COG0432@2|Bacteria	2|Bacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
CMS1_k127_2593854_6	398511.BpOF4_18515	1.029e-123	407.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4HASW@91061|Bacilli,1ZB29@1386|Bacillus	91061|Bacilli	I	Belongs to the thiolase family	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
CMS1_k127_2593854_25	1304885.AUEY01000017_gene3759	5.384e-30	120.0	COG1598@1|root,COG1598@2|Bacteria,1NCC0@1224|Proteobacteria,434UG@68525|delta/epsilon subdivisions,2WZ5D@28221|Deltaproteobacteria,2MNZY@213118|Desulfobacterales	28221|Deltaproteobacteria	S	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
CMS1_k127_2593854_16	1303518.CCALI_00287	3.117e-65	233.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
CMS1_k127_2593854_13	1550091.JROE01000004_gene1604	4.378e-76	282.0	COG1554@1|root,COG1554@2|Bacteria,4NG60@976|Bacteroidetes,1IQ6B@117747|Sphingobacteriia	976|Bacteroidetes	G	Glycosyl hydrolase family 65, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hyd_65N_2
CMS1_k127_2593854_2	314230.DSM3645_23496	3.707e-170	546.0	COG3119@1|root,COG3119@2|Bacteria,2IXP1@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
CMS1_k127_2593854_30	1303518.CCALI_01416	6.407e-10	67.0	28UXW@1|root,2ZH1P@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2593854_12	880073.Calab_0190	1.688e-81	278.0	COG0221@1|root,COG0221@2|Bacteria,2NPVX@2323|unclassified Bacteria	2|Bacteria	C	Inorganic pyrophosphatase	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
CMS1_k127_2593854_22	290318.Cvib_0740	8.228e-35	146.0	COG1342@1|root,COG1342@2|Bacteria,1FF1T@1090|Chlorobi	1090|Chlorobi	S	Belongs to the UPF0251 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF134
CMS1_k127_2593854_1	1283300.ATXB01000001_gene2143	3.348e-200	637.0	COG0457@1|root,COG0457@2|Bacteria,1N0A9@1224|Proteobacteria,1RZSZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_7
CMS1_k127_2593854_19	518766.Rmar_1212	2.926e-60	217.0	COG1801@1|root,COG1801@2|Bacteria,4NHAD@976|Bacteroidetes,1FK58@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
CMS1_k127_2593854_21	1499967.BAYZ01000050_gene2839	4.796e-39	147.0	COG0640@1|root,COG0640@2|Bacteria,2NQ13@2323|unclassified Bacteria	2|Bacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	arsR	-	3.6.4.12	ko:K03655,ko:K03892	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	HTH_20,HTH_5
CMS1_k127_2593854_4	595460.RRSWK_03127	4.717e-146	480.0	COG0701@1|root,COG0701@2|Bacteria,2J0GE@203682|Planctomycetes	203682|Planctomycetes	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
CMS1_k127_2593854_27	1499967.BAYZ01000050_gene2842	1.59e-24	106.0	COG0526@1|root,COG0526@2|Bacteria,2NQ71@2323|unclassified Bacteria	2|Bacteria	CO	Thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4369,Thioredoxin_3
CMS1_k127_2593854_23	404589.Anae109_3645	7.506e-33	144.0	COG0526@1|root,COG0526@2|Bacteria,1N0R9@1224|Proteobacteria,42UD9@68525|delta/epsilon subdivisions,2WQ0H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	CO	PFAM Thioredoxin	trx-2	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
CMS1_k127_2593854_8	909663.KI867150_gene1425	3.29e-104	343.0	COG4232@1|root,COG4232@2|Bacteria,1PK9S@1224|Proteobacteria,42PV0@68525|delta/epsilon subdivisions,2WJPK@28221|Deltaproteobacteria,2MS43@213462|Syntrophobacterales	28221|Deltaproteobacteria	CO	PFAM cytochrome c biogenesis protein, transmembrane region	dsbD	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
CMS1_k127_2593854_24	1280941.HY2_02705	2.447e-31	126.0	COG0640@1|root,COG0640@2|Bacteria,1MZAU@1224|Proteobacteria,2U9NV@28211|Alphaproteobacteria,4408Z@69657|Hyphomonadaceae	28211|Alphaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20
CMS1_k127_2593854_18	338963.Pcar_1772	2.164e-63	225.0	COG0394@1|root,COG0394@2|Bacteria,1MWYQ@1224|Proteobacteria,42RQI@68525|delta/epsilon subdivisions,2WNEC@28221|Deltaproteobacteria,43V3P@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Low molecular weight phosphatase family	arsC	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
CMS1_k127_2593854_28	1347342.BN863_6590	2.538e-23	106.0	COG0730@1|root,COG0730@2|Bacteria,4NIJ9@976|Bacteroidetes,1I0SR@117743|Flavobacteriia	976|Bacteroidetes	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
CMS1_k127_2595952_3	945713.IALB_2899	1.917e-49	183.0	28NYH@1|root,2ZBVN@2|Bacteria	2|Bacteria	S	Belongs to the UPF0403 family	yqiW	-	-	-	-	-	-	-	-	-	-	-	Disulph_isomer
CMS1_k127_2595952_2	234267.Acid_0753	7.573e-110	369.0	COG0673@1|root,COG0673@2|Bacteria,3Y4KS@57723|Acidobacteria	57723|Acidobacteria	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_2595952_0	1321778.HMPREF1982_01682	8.284e-192	607.0	COG1486@1|root,COG1486@2|Bacteria,1TQ9I@1239|Firmicutes,24995@186801|Clostridia,26AI4@186813|unclassified Clostridiales	186801|Clostridia	G	Family 4 glycosyl hydrolase	-	-	3.2.1.22	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_4,Glyco_hydro_4C
CMS1_k127_2595952_1	207954.MED92_06991	1.356e-116	383.0	COG0535@1|root,COG0535@2|Bacteria,1MU07@1224|Proteobacteria,1RZ9D@1236|Gammaproteobacteria,1XHTK@135619|Oceanospirillales	135619|Oceanospirillales	S	Radical SAM superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
CMS1_k127_2595952_4	56107.Cylst_5647	2.768e-16	83.0	COG1724@1|root,COG1724@2|Bacteria,1GHIC@1117|Cyanobacteria,1HT6U@1161|Nostocales	1117|Cyanobacteria	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
CMS1_k127_2595952_5	1173022.Cri9333_4093	4.749e-11	64.0	COG1598@1|root,COG1598@2|Bacteria,1G9W5@1117|Cyanobacteria,1HGUF@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2610582_0	886293.Sinac_0401	4.527e-57	220.0	COG5426@1|root,COG5426@2|Bacteria,2IWWQ@203682|Planctomycetes	203682|Planctomycetes	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	GATase1_like
CMS1_k127_2610582_1	497964.CfE428DRAFT_0780	2.109e-12	80.0	COG1196@1|root,COG1196@2|Bacteria,46TD8@74201|Verrucomicrobia	74201|Verrucomicrobia	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_261538_1	335543.Sfum_1413	1.023e-17	84.0	COG0601@1|root,COG0601@2|Bacteria,1NS80@1224|Proteobacteria,42N5D@68525|delta/epsilon subdivisions,2WIRR@28221|Deltaproteobacteria,2MQBC@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_261538_0	335543.Sfum_1411	6.334e-162	528.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,42MFK@68525|delta/epsilon subdivisions,2WKBU@28221|Deltaproteobacteria,2MQ6I@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	PFAM Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035,ko:K13893	ko02010,ko02024,map02010,map02024	M00239,M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
CMS1_k127_261538_2	697281.Mahau_2672	1.048e-08	67.0	COG0407@1|root,COG0407@2|Bacteria,1VJHK@1239|Firmicutes,24TV3@186801|Clostridia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
CMS1_k127_2617113_1	1121033.AUCF01000008_gene5732	2.059e-21	108.0	COG0744@1|root,COG0744@2|Bacteria,1RDAQ@1224|Proteobacteria,2U0NP@28211|Alphaproteobacteria,2JS5A@204441|Rhodospirillales	204441|Rhodospirillales	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
CMS1_k127_2617113_0	1449063.JMLS01000013_gene5979	3.9e-81	300.0	COG1554@1|root,COG1554@2|Bacteria	2|Bacteria	G	hydrolase, family 65, central catalytic	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hyd_65N_2,Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m
CMS1_k127_2638842_0	1366050.N234_09795	2.542e-196	627.0	COG0419@1|root,COG0419@2|Bacteria,1REER@1224|Proteobacteria,2VY5A@28216|Betaproteobacteria,1KDNG@119060|Burkholderiaceae	28216|Betaproteobacteria	L	ATPase involved in DNA repair	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2638842_1	1366050.N234_09800	0.0006911	42.0	COG0222@1|root,COG0222@2|Bacteria,1RAQC@1224|Proteobacteria,2VZH9@28216|Betaproteobacteria,1KE2Z@119060|Burkholderiaceae	28216|Betaproteobacteria	J	ribosome binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2655515_0	1121430.JMLG01000006_gene1775	4.766e-73	261.0	COG1092@1|root,COG1092@2|Bacteria,1TRAJ@1239|Firmicutes,247TI@186801|Clostridia,261AH@186807|Peptococcaceae	186801|Clostridia	J	SAM-dependent methyltransferase	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,PUA
CMS1_k127_2692153_3	1168034.FH5T_19015	2.5e-55	200.0	COG0644@1|root,COG0644@2|Bacteria,4P040@976|Bacteroidetes	976|Bacteroidetes	C	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2692153_6	237368.SCABRO_04028	2.976e-27	117.0	COG0644@1|root,COG0664@1|root,COG0644@2|Bacteria,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	prnA	-	1.14.19.9	ko:K07058,ko:K14266	ko00404,ko01130,map00404,map01130	M00789,M00790	R09570	RC00949	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_5,Trp_halogenase,cNMP_binding
CMS1_k127_2692153_0	331678.Cphamn1_1855	3.057e-140	464.0	COG0493@1|root,COG0493@2|Bacteria,1FDFY@1090|Chlorobi	1090|Chlorobi	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_20,Fer4_7,Fer4_9,Pyr_redox_2
CMS1_k127_2692153_2	1304874.JAFY01000002_gene966	2.535e-129	418.0	COG1878@1|root,COG1878@2|Bacteria,3TC4G@508458|Synergistetes	508458|Synergistetes	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
CMS1_k127_2692153_4	234267.Acid_3334	4.433e-51	197.0	COG3391@1|root,COG3391@2|Bacteria,3Y3R3@57723|Acidobacteria	57723|Acidobacteria	S	TIGRFAM 40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
CMS1_k127_2692153_1	1123278.KB893623_gene3429	3.15e-131	436.0	COG1680@1|root,COG1680@2|Bacteria,4NEVS@976|Bacteroidetes,47NMR@768503|Cytophagia	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS1_k127_2692153_5	1219084.AP014508_gene348	7.177e-37	144.0	COG0329@1|root,COG0329@2|Bacteria,2GDWI@200918|Thermotogae	200918|Thermotogae	E	Dihydrodipicolinate synthetase family	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
CMS1_k127_2696278_5	1139996.OMQ_01508	1.973e-38	154.0	COG1011@1|root,COG1011@2|Bacteria,1TS3W@1239|Firmicutes,4HADE@91061|Bacilli	91061|Bacilli	S	hydrolase (HAD superfamily)	ysaA	-	3.1.3.5,3.8.1.2	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346,R05287	RC00017,RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
CMS1_k127_2696278_6	65071.PYU1_T000032	4.35e-10	66.0	COG0666@1|root,KOG4177@2759|Eukaryota,1MGRY@121069|Pythiales	121069|Pythiales	M	Ankyrin repeats (3 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_4,Ank_5
CMS1_k127_2696278_1	439235.Dalk_4026	1.944e-120	401.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42YUK@68525|delta/epsilon subdivisions,2WTYA@28221|Deltaproteobacteria,2MMJC@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
CMS1_k127_2696278_4	1283300.ATXB01000002_gene3206	2.451e-47	178.0	COG0454@1|root,COG0456@2|Bacteria,1RHB7@1224|Proteobacteria,1S3TD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	L-2,4-diaminobutyric acid acetyltransferase	ectA	-	2.3.1.178	ko:K06718	ko00260,ko01100,ko01120,map00260,map01100,map01120	M00033	R06978	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
CMS1_k127_2696278_0	1247726.MIM_c17770	1.356e-173	557.0	COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,2VI11@28216|Betaproteobacteria,3T2Y8@506|Alcaligenaceae	28216|Betaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	ectB	-	2.6.1.76	ko:K00836	ko00260,ko01100,ko01120,ko01210,ko01230,map00260,map01100,map01120,map01210,map01230	M00033	R06977	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CMS1_k127_2696278_3	717231.Flexsi_0826	6.926e-55	197.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	ectC	-	4.2.1.108	ko:K06720	ko00260,ko01100,ko01120,map00260,map01100,map01120	M00033	R06979	RC01729	ko00000,ko00001,ko00002,ko01000	-	-	-	Ectoine_synth
CMS1_k127_2696278_2	472759.Nhal_2706	2.904e-79	269.0	COG5285@1|root,COG5285@2|Bacteria,1MWD5@1224|Proteobacteria,1RSBY@1236|Gammaproteobacteria,1WZJ3@135613|Chromatiales	135613|Chromatiales	Q	PFAM Phytanoyl-CoA dioxygenase	-	-	1.14.11.55	ko:K10674	ko00260,ko01120,map00260,map01120	-	R08050	RC00661	ko00000,ko00001,ko01000	-	-	-	PhyH
CMS1_k127_2699400_1	1121935.AQXX01000072_gene3	7.138e-15	88.0	COG1572@1|root,COG2304@1|root,COG3209@1|root,COG1572@2|Bacteria,COG2304@2|Bacteria,COG3209@2|Bacteria,1QU09@1224|Proteobacteria,1T39R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	N	Protein involved in outer membrane biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,RHS_repeat
CMS1_k127_2699400_0	313603.FB2170_05940	9.094e-77	276.0	COG3119@1|root,COG3119@2|Bacteria,4NGX1@976|Bacteroidetes,1I0ER@117743|Flavobacteriia	976|Bacteroidetes	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CMS1_k127_2701532_2	706587.Desti_5231	1.289e-14	79.0	COG1807@1|root,COG1807@2|Bacteria,1P7ER@1224|Proteobacteria	1224|Proteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2701532_0	1218074.BAXZ01000013_gene2969	4.515e-99	340.0	COG0382@1|root,COG0382@2|Bacteria,1MXCM@1224|Proteobacteria,2VKY4@28216|Betaproteobacteria,1K0JV@119060|Burkholderiaceae	28216|Betaproteobacteria	H	PFAM UbiA prenyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	HAD,UbiA
CMS1_k127_2701532_1	1458357.BG58_25845	3.119e-37	150.0	COG0500@1|root,COG0500@2|Bacteria,1PIRJ@1224|Proteobacteria,2W7AU@28216|Betaproteobacteria,1KE80@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2712221_1	1379281.AVAG01000102_gene1722	1.395e-15	78.0	COG0394@1|root,COG0394@2|Bacteria,1MWYQ@1224|Proteobacteria,42RQI@68525|delta/epsilon subdivisions,2WNEC@28221|Deltaproteobacteria,2MBFG@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM Protein-tyrosine phosphatase, low molecular weight	arsC	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
CMS1_k127_2712221_0	244581.IM40_01805	9.96e-91	306.0	COG0623@1|root,COG0623@2|Bacteria,1MV05@1224|Proteobacteria,2TSU4@28211|Alphaproteobacteria,47EXU@766|Rickettsiales	766|Rickettsiales	I	Enoyl- acyl-carrier-protein reductase NADH	fabI	GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901576	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS1_k127_2712221_2	994573.T472_0205610	2.635e-08	61.0	COG1024@1|root,COG1024@2|Bacteria,1V2IE@1239|Firmicutes,25CCB@186801|Clostridia,36R7Z@31979|Clostridiaceae	186801|Clostridia	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS1_k127_2735766_0	443598.AUFA01000007_gene4401	5.425e-07	63.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,2U5A1@28211|Alphaproteobacteria,3JSQ9@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	Sigma-70, region 4	sigW	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_2737448_3	314278.NB231_06900	4.565e-73	248.0	COG0500@1|root,COG0500@2|Bacteria,1N3PV@1224|Proteobacteria,1S1BV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
CMS1_k127_2737448_0	1304880.JAGB01000001_gene461	7.972e-170	542.0	COG4952@1|root,COG4952@2|Bacteria,1UD8H@1239|Firmicutes,24HDU@186801|Clostridia	186801|Clostridia	G	isomerase	-	-	5.3.1.14	ko:K01820	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01906,R02437,R06589	RC00376,RC00434,RC00516	ko00000,ko00001,ko01000	-	-	-	-
CMS1_k127_2737448_8	500637.PROVRUST_06702	3.341e-06	55.0	COG0666@1|root,COG0666@2|Bacteria,1N952@1224|Proteobacteria,1RPZA@1236|Gammaproteobacteria,3Z8DG@586|Providencia	1236|Gammaproteobacteria	S	ankyrin repeat	-	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank,Ank_2,Ank_4
CMS1_k127_2737448_1	1380387.JADM01000003_gene2595	1.044e-144	479.0	COG1409@1|root,COG1409@2|Bacteria,1NS3S@1224|Proteobacteria,1RR8K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
CMS1_k127_2737448_7	247490.KSU1_C1333	1.506e-15	88.0	COG4968@1|root,COG4968@2|Bacteria,2J519@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CMS1_k127_2737448_6	428125.CLOLEP_01116	3.503e-19	97.0	COG2207@1|root,COG2207@2|Bacteria,1TQ2W@1239|Firmicutes,24A5W@186801|Clostridia,3WIGP@541000|Ruminococcaceae	186801|Clostridia	K	transcriptional regulator AraC family	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18,HTH_AraC
CMS1_k127_2737448_5	269799.Gmet_3333	6.706e-37	149.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,42SV9@68525|delta/epsilon subdivisions,2WPXX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Phosphoribosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
CMS1_k127_2737448_4	1121440.AUMA01000005_gene2690	3.892e-60	226.0	COG0534@1|root,COG0534@2|Bacteria,1MUAM@1224|Proteobacteria,42MX0@68525|delta/epsilon subdivisions,2WM16@28221|Deltaproteobacteria,2M98N@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	PFAM Multi antimicrobial extrusion protein MatE	norM-2	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
CMS1_k127_2737448_2	234267.Acid_7164	3.354e-95	336.0	COG5434@1|root,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_lyase,Beta_helix,CBM_6,F5_F8_type_C,Hepar_II_III,Hepar_II_III_N
CMS1_k127_2742686_2	392500.Swoo_3062	2.82e-21	98.0	2F10C@1|root,33U1V@2|Bacteria,1NUUY@1224|Proteobacteria,1SNP3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2742686_0	1304885.AUEY01000104_gene2548	1.242e-125	410.0	COG0702@1|root,COG0702@2|Bacteria,1Q438@1224|Proteobacteria,439WM@68525|delta/epsilon subdivisions,2X29K@28221|Deltaproteobacteria,2MPBK@213118|Desulfobacterales	28221|Deltaproteobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
CMS1_k127_2742686_1	426117.M446_5908	4.01e-59	219.0	COG3391@1|root,COG3391@2|Bacteria,1R3YF@1224|Proteobacteria,2TUFI@28211|Alphaproteobacteria,1JU0K@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
CMS1_k127_2742686_3	1123075.AUDP01000017_gene3200	8.866e-06	56.0	COG0705@1|root,COG0705@2|Bacteria,1VXV8@1239|Firmicutes,25EQ2@186801|Clostridia	186801|Clostridia	P	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2744355_0	314278.NB231_17398	3.102e-102	336.0	COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,1RMP0@1236|Gammaproteobacteria,1WY4V@135613|Chromatiales	135613|Chromatiales	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CMS1_k127_2744355_1	349521.HCH_06289	3.338e-32	129.0	COG0006@1|root,COG0006@2|Bacteria,1MWUT@1224|Proteobacteria,1RZSD@1236|Gammaproteobacteria,1XNGP@135619|Oceanospirillales	135619|Oceanospirillales	E	Creatinase/Prolidase N-terminal domain	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016812,GO:0019752,GO:0032787,GO:0042399,GO:0042400,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046700,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	3.4.13.9,3.5.4.44	ko:K01271,ko:K15783	ko00260,ko01100,map00260,map01100	-	R09800	RC02661	ko00000,ko00001,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
CMS1_k127_2750445_0	1229172.JQFA01000002_gene3206	9.911e-252	791.0	COG3408@1|root,COG3408@2|Bacteria,1GQ41@1117|Cyanobacteria,1HI32@1150|Oscillatoriales	1117|Cyanobacteria	G	Glycosyl hydrolase family 63 C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_63
CMS1_k127_2751761_18	351160.RCIX614	1.261e-09	70.0	arCOG12598@1|root,arCOG12598@2157|Archaea,2Y5ZC@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2751761_10	313628.LNTAR_01367	6.518e-78	269.0	COG1606@1|root,COG1606@2|Bacteria	2|Bacteria	L	tRNA processing	larE	-	4.99.1.12	ko:K06864,ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	ATP_bind_3,Asn_synthase,NAD_synthase,QueC
CMS1_k127_2751761_0	313628.LNTAR_01372	5.138e-154	501.0	COG0621@1|root,COG0621@2|Bacteria	2|Bacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	yqeV	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
CMS1_k127_2751761_4	313628.LNTAR_01377	1.237e-117	398.0	COG0260@1|root,COG0260@2|Bacteria	2|Bacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	GO:0001073,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006351,GO:0006355,GO:0006508,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009056,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016787,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019538,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042150,GO:0043170,GO:0043171,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043244,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0097718,GO:0140096,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1903506,GO:2000112,GO:2001141	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
CMS1_k127_2751761_7	68199.JNZO01000008_gene7457	1.035e-112	376.0	COG0190@1|root,COG0190@2|Bacteria,2GJZS@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD1	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
CMS1_k127_2751761_20	344747.PM8797T_15451	2.669e-06	56.0	2EGPA@1|root,33AFD@2|Bacteria,2J1H0@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_2
CMS1_k127_2751761_15	102125.Xen7305DRAFT_00051080	5.132e-44	170.0	COG2755@1|root,COG2755@2|Bacteria,1G8DF@1117|Cyanobacteria,3VMR7@52604|Pleurocapsales	1117|Cyanobacteria	E	PFAM GDSL-like Lipase Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS1_k127_2751761_16	1499967.BAYZ01000065_gene6104	4.765e-43	164.0	COG1544@1|root,COG1544@2|Bacteria,2NPYS@2323|unclassified Bacteria	2|Bacteria	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	raiA	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
CMS1_k127_2751761_8	1385514.N782_10030	4.035e-85	293.0	COG1493@1|root,COG1493@2|Bacteria,1TP5Z@1239|Firmicutes,4HAXR@91061|Bacilli,2Y96K@289201|Pontibacillus	91061|Bacilli	F	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	hprK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
CMS1_k127_2751761_9	756499.Desde_4037	9.114e-85	289.0	COG1660@1|root,COG1660@2|Bacteria,1TPS4@1239|Firmicutes,248KQ@186801|Clostridia,2616Z@186807|Peptococcaceae	186801|Clostridia	S	Displays ATPase and GTPase activities	yvcJ	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
CMS1_k127_2751761_17	290397.Adeh_0152	2.551e-24	106.0	COG1925@1|root,COG1925@2|Bacteria,1N6RM@1224|Proteobacteria,42V5C@68525|delta/epsilon subdivisions,2WRC4@28221|Deltaproteobacteria,2Z1YQ@29|Myxococcales	28221|Deltaproteobacteria	G	PTS HPr component phosphorylation site	ptsH	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
CMS1_k127_2751761_1	273068.TTE2334	1.492e-149	493.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia,42FHW@68295|Thermoanaerobacterales	186801|Clostridia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsP	-	2.7.3.9,2.7.9.2	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
CMS1_k127_2751761_5	194439.CT0125	3.787e-117	388.0	COG0743@1|root,COG0743@2|Bacteria,1FD70@1090|Chlorobi	1090|Chlorobi	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
CMS1_k127_2751761_13	1297742.A176_06757	1.349e-55	217.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,42NJ0@68525|delta/epsilon subdivisions,2WJ7A@28221|Deltaproteobacteria,2YTYT@29|Myxococcales	28221|Deltaproteobacteria	M	Peptidase family M50	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
CMS1_k127_2751761_3	1410653.JHVC01000005_gene2451	3.664e-135	445.0	COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,24811@186801|Clostridia,36EUA@31979|Clostridiaceae	186801|Clostridia	E	Belongs to the aspartokinase family	thrA	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
CMS1_k127_2751761_19	1906.SFRA_10880	1.34e-07	56.0	COG1724@1|root,COG1724@2|Bacteria	2|Bacteria	N	mRNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
CMS1_k127_2751761_2	357808.RoseRS_1428	9.033e-142	466.0	COG0469@1|root,COG0469@2|Bacteria,2G5YE@200795|Chloroflexi,375C1@32061|Chloroflexia	32061|Chloroflexia	G	Belongs to the pyruvate kinase family	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
CMS1_k127_2751761_14	1329516.JPST01000005_gene1396	1.149e-47	180.0	COG0500@1|root,COG2226@2|Bacteria,1V45D@1239|Firmicutes,4HG4Y@91061|Bacilli,27BS9@186824|Thermoactinomycetaceae	91061|Bacilli	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS1_k127_2751761_11	574087.Acear_0300	6.832e-69	253.0	COG4365@1|root,COG4365@2|Bacteria,1TQ2P@1239|Firmicutes,24DMW@186801|Clostridia	186801|Clostridia	S	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH	bshC	-	-	ko:K22136	-	-	-	-	ko00000	-	-	-	BshC
CMS1_k127_2751761_12	880073.Calab_0107	8.787e-59	212.0	COG2120@1|root,COG2120@2|Bacteria,2NPAV@2323|unclassified Bacteria	2|Bacteria	S	GlcNAc-PI de-N-acetylase	bshB1	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
CMS1_k127_2751761_6	1047013.AQSP01000125_gene2631	7.314e-115	383.0	COG0438@1|root,COG0438@2|Bacteria,2NNTN@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferases group 1	bshA	GO:0003674,GO:0003824,GO:0016740,GO:0016757	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_transf_4,Glycos_transf_1
CMS1_k127_2765479_1	269799.Gmet_2608	1.017e-24	114.0	COG3712@1|root,COG3712@2|Bacteria	2|Bacteria	PT	iron ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	DUF4974,FecR,VPEP
CMS1_k127_2765479_0	756272.Plabr_3539	1.799e-86	303.0	COG0673@1|root,COG0673@2|Bacteria,2IX6I@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_2773942_2	1232410.KI421425_gene1554	8.257e-83	288.0	COG1361@1|root,COG1361@2|Bacteria,1R5G4@1224|Proteobacteria,42T0V@68525|delta/epsilon subdivisions,2WPRT@28221|Deltaproteobacteria,43TPS@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,SdrD_B
CMS1_k127_2773942_3	1278073.MYSTI_04402	1.577e-59	218.0	COG0500@1|root,COG2226@2|Bacteria,1MW7J@1224|Proteobacteria,43C6X@68525|delta/epsilon subdivisions	1224|Proteobacteria	Q	O-methyltransferase	crtF	-	2.1.1.210	ko:K09846	ko00906,ko01100,map00906,map01100	-	R07521,R07524,R07527,R07529,R07533,R07535	RC00003,RC02082	ko00000,ko00001,ko01000	-	-	-	Dimerisation2,Methyltransf_2
CMS1_k127_2773942_4	1031711.RSPO_c00521	2.747e-33	130.0	COG3676@1|root,COG3676@2|Bacteria,1QTF7@1224|Proteobacteria,2VQDW@28216|Betaproteobacteria	28216|Betaproteobacteria	L	ISXO2-like transposase domain	-	-	-	ko:K07488	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS1595
CMS1_k127_2773942_0	42256.RradSPS_2616	1.459e-226	716.0	COG0028@1|root,COG0028@2|Bacteria,2GM6Y@201174|Actinobacteria,4CRM8@84995|Rubrobacteria	84995|Rubrobacteria	EH	COG COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase pyruvate dehydrogenase (cytochrome) glyoxylate carboligase phosphonopyruvate decarboxylase Amino acid transport and metabolism Coenzyme metabolism	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS1_k127_2773942_1	420662.Mpe_B0539	2.264e-216	679.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,2VI46@28216|Betaproteobacteria,1KJ6S@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
CMS1_k127_2773942_5	388051.AUFE01000070_gene3819	3.429e-22	111.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2VKH1@28216|Betaproteobacteria,1JZT2@119060|Burkholderiaceae	28216|Betaproteobacteria	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
CMS1_k127_2784915_1	1047171.Mycgr3P10419	8.022e-09	69.0	COG0666@1|root,KOG4177@2759|Eukaryota,39TJ8@33154|Opisthokonta,3P14I@4751|Fungi,3QRFF@4890|Ascomycota,203YU@147541|Dothideomycetes,3MNED@451867|Dothideomycetidae	4751|Fungi	M	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank,Ank_2,Ank_4
CMS1_k127_2784915_0	497964.CfE428DRAFT_6196	1.216e-24	121.0	COG2319@1|root,COG2319@2|Bacteria,46THG@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF4034)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4034
CMS1_k127_2784915_2	1254432.SCE1572_09930	3.204e-08	67.0	COG4677@1|root,COG4677@2|Bacteria,1PXT2@1224|Proteobacteria,434TW@68525|delta/epsilon subdivisions,2WZ4T@28221|Deltaproteobacteria,2Z1BV@29|Myxococcales	28221|Deltaproteobacteria	G	pectinesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	NosD
CMS1_k127_2784915_3	198094.BA_0564	2.496e-05	49.0	COG0666@1|root,COG0666@2|Bacteria,1V2DE@1239|Firmicutes,4HGU4@91061|Bacilli,1ZFPZ@1386|Bacillus	91061|Bacilli	S	Ankyrin repeat	-	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank,Ank_2,Ank_4
CMS1_k127_2804379_3	1121904.ARBP01000040_gene530	4.417e-119	400.0	COG3119@1|root,COG3119@2|Bacteria,4NGX1@976|Bacteroidetes,47K2H@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS1_k127_2804379_10	159450.NH14_14635	1.368e-51	199.0	COG1653@1|root,COG1653@2|Bacteria,1QKXW@1224|Proteobacteria,2VX8Q@28216|Betaproteobacteria,1K3W3@119060|Burkholderiaceae	28216|Betaproteobacteria	G	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K02027,ko:K17244	ko02010,map02010	M00207,M00601	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.40	-	-	SBP_bac_1,SBP_bac_8
CMS1_k127_2804379_5	756272.Plabr_3022	3.327e-84	295.0	COG5434@1|root,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Pectate_lyase_3
CMS1_k127_2804379_4	497964.CfE428DRAFT_2358	6.698e-108	364.0	COG0513@1|root,COG0513@2|Bacteria,46S5M@74201|Verrucomicrobia	74201|Verrucomicrobia	L	helicase superfamily c-terminal domain	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
CMS1_k127_2804379_1	545695.TREAZ_2888	6.007e-150	482.0	COG1063@1|root,COG1063@2|Bacteria,2J6S3@203691|Spirochaetes	203691|Spirochaetes	E	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_2804379_7	1121904.ARBP01000022_gene3520	5.15e-78	273.0	COG1621@1|root,COG1621@2|Bacteria,4PNCP@976|Bacteroidetes	976|Bacteroidetes	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2804379_19	1121930.AQXG01000003_gene2523	0.0001883	52.0	2DR43@1|root,33A2W@2|Bacteria,4P6ZC@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2804379_9	313628.LNTAR_20258	4.09e-67	244.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
CMS1_k127_2804379_0	1297742.A176_06834	1.145e-169	556.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,42MB1@68525|delta/epsilon subdivisions,2WJ76@28221|Deltaproteobacteria,2YUHH@29|Myxococcales	28221|Deltaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
CMS1_k127_2804379_14	1242864.D187_010172	4.526e-32	141.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	estX	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
CMS1_k127_2804379_2	1288963.ADIS_1386	5.037e-148	485.0	28HHT@1|root,2Z7TE@2|Bacteria,4NIHS@976|Bacteroidetes,47MAA@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2804379_13	289377.HL41_03860	3.686e-34	140.0	COG2045@1|root,COG2045@2|Bacteria,2GGYU@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	H	2-phosphosulpholactate phosphatase	-	-	3.1.3.71	ko:K05979	ko00680,ko01120,map00680,map01120	M00358	R05789	RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	2-ph_phosp
CMS1_k127_2804379_6	1122179.KB890424_gene3635	1.521e-80	279.0	COG0492@1|root,COG0492@2|Bacteria,4NDVS@976|Bacteroidetes,1INU1@117747|Sphingobacteriia	976|Bacteroidetes	O	Pyridine nucleotide-disulphide oxidoreductase	ypdA	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_3
CMS1_k127_2804379_8	484770.UFO1_0994	1.043e-76	266.0	COG0647@1|root,COG0647@2|Bacteria,1TQGM@1239|Firmicutes,4H1Z6@909932|Negativicutes	909932|Negativicutes	G	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro	-	-	-	ko:K02566	-	-	-	-	ko00000	-	-	-	Hydrolase_6,Hydrolase_like
CMS1_k127_2804379_17	1313265.JNIE01000002_gene806	1.42e-07	65.0	COG0593@1|root,COG0593@2|Bacteria,2G3RG@200783|Aquificae	200783|Aquificae	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
CMS1_k127_2804379_11	1178537.BA1_00510	3.784e-47	181.0	COG0631@1|root,COG0631@2|Bacteria,1V6K5@1239|Firmicutes,4HCDR@91061|Bacilli,1ZCYC@1386|Bacillus	91061|Bacilli	T	phosphatase	stp	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
CMS1_k127_2804379_12	760192.Halhy_2685	2.63e-46	177.0	COG2908@1|root,COG2908@2|Bacteria,4NEF1@976|Bacteroidetes,1IQ9A@117747|Sphingobacteriia	976|Bacteroidetes	S	Calcineurin-like phosphoesterase	lpxH	-	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Metallophos,Metallophos_2
CMS1_k127_2804379_15	1460640.JCM19046_3764	7.277e-27	118.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,4HIQ4@91061|Bacilli,1ZRQU@1386|Bacillus	91061|Bacilli	U	Signal peptidase, peptidase S26	sipT	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
CMS1_k127_2804379_16	243231.GSU0801	2.859e-09	67.0	COG3637@1|root,COG3637@2|Bacteria,1QUUK@1224|Proteobacteria	1224|Proteobacteria	M	Alginate export	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp
CMS1_k127_2818325_2	762376.AXYL_04411	5.712e-78	273.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VPJ4@28216|Betaproteobacteria,3T36P@506|Alcaligenaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
CMS1_k127_2818325_0	1125973.JNLC01000010_gene1417	5.43e-214	681.0	COG2936@1|root,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,2TU0R@28211|Alphaproteobacteria,3JZ96@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
CMS1_k127_2818325_1	1125973.JNLC01000010_gene1411	2.609e-118	392.0	COG1073@1|root,COG1073@2|Bacteria,1MXJ3@1224|Proteobacteria,2TVHP@28211|Alphaproteobacteria,3JQQG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	hydrolases or acyltransferases, alpha beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,DUF1100,Peptidase_S9
CMS1_k127_2818325_3	314285.KT71_08625	5.998e-48	178.0	COG1525@1|root,COG1525@2|Bacteria,1N145@1224|Proteobacteria,1S9I3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	nuclease	Z012_04225	GO:0003674,GO:0003824,GO:0004518,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575	3.1.31.1	ko:K01174	-	-	-	-	ko00000,ko01000	-	-	-	Excalibur,SNase
CMS1_k127_2820889_1	998674.ATTE01000001_gene927	4.646e-06	59.0	COG1028@1|root,COG3405@1|root,COG1028@2|Bacteria,COG3405@2|Bacteria,1MWC8@1224|Proteobacteria,1S1X8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
CMS1_k127_2820889_0	479433.Caci_5655	3.208e-07	58.0	COG0454@1|root,COG0454@2|Bacteria,2I32C@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
CMS1_k127_2820889_2	941824.TCEL_00788	4.626e-05	46.0	COG0393@1|root,COG0393@2|Bacteria,1VADM@1239|Firmicutes,24NFX@186801|Clostridia,36K0Z@31979|Clostridiaceae	186801|Clostridia	S	Belongs to the UPF0145 family	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
CMS1_k127_2825953_4	331678.Cphamn1_0337	4.444e-74	256.0	COG0610@1|root,COG1943@1|root,COG0610@2|Bacteria,COG1943@2|Bacteria,1FEZT@1090|Chlorobi	1090|Chlorobi	LV	Subunit R is required for both nuclease and ATPase activities, but not for modification	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HSDR_N,ResIII,Y1_Tnp
CMS1_k127_2825953_12	631362.Thi970DRAFT_00076	1.449e-23	102.0	COG1724@1|root,COG1724@2|Bacteria,1N5JA@1224|Proteobacteria	1224|Proteobacteria	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
CMS1_k127_2825953_0	869213.JCM21142_93371	1.857e-180	574.0	COG3669@1|root,COG3669@2|Bacteria,4NE74@976|Bacteroidetes,47KQM@768503|Cytophagia	976|Bacteroidetes	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos
CMS1_k127_2825953_11	204669.Acid345_1569	8.397e-26	112.0	COG4968@1|root,COG4968@2|Bacteria,3Y98E@57723|Acidobacteria,2JP4Y@204432|Acidobacteriia	57723|Acidobacteria	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
CMS1_k127_2825953_8	1396418.BATQ01000186_gene2187	4.482e-42	162.0	COG1595@1|root,COG1595@2|Bacteria,46V3R@74201|Verrucomicrobia,2IVSK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_2825953_7	240015.ACP_0132	2.713e-42	162.0	COG2318@1|root,COG2318@2|Bacteria,3Y579@57723|Acidobacteria,2JJPN@204432|Acidobacteriia	204432|Acidobacteriia	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
CMS1_k127_2825953_6	1123242.JH636436_gene499	7.3e-57	203.0	COG1225@1|root,COG1225@2|Bacteria,2IZIQ@203682|Planctomycetes	203682|Planctomycetes	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
CMS1_k127_2825953_5	1121904.ARBP01000013_gene440	2.088e-68	239.0	COG1082@1|root,COG2152@1|root,COG1082@2|Bacteria,COG2152@2|Bacteria,4NGDZ@976|Bacteroidetes,47KUI@768503|Cytophagia	976|Bacteroidetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CMS1_k127_2825953_10	1118054.CAGW01000117_gene3377	6.011e-28	130.0	COG2267@1|root,COG2267@2|Bacteria,1TRMT@1239|Firmicutes,4HE23@91061|Bacilli,277PG@186822|Paenibacillaceae	91061|Bacilli	I	Serine aminopeptidase, S33	pepI	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
CMS1_k127_2825953_9	234267.Acid_1122	4.898e-33	148.0	COG1506@1|root,COG1506@2|Bacteria,3Y3MA@57723|Acidobacteria	57723|Acidobacteria	E	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	AXE1
CMS1_k127_2825953_13	1226325.HMPREF1548_00223	5.928e-20	106.0	COG4409@1|root,COG4409@2|Bacteria,1V5Q1@1239|Firmicutes,24FGZ@186801|Clostridia,36W5Z@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_130,Glyco_hydro_32N,Glyco_hydro_43
CMS1_k127_2825953_14	1042376.AFPK01000074_gene2390	0.0001459	55.0	COG2152@1|root,COG2152@2|Bacteria,4NG7B@976|Bacteroidetes,1IIR4@117743|Flavobacteriia	976|Bacteroidetes	G	beta-1,4-mannooligosaccharide phosphorylase	-	-	2.4.1.339,2.4.1.340	ko:K20885	-	-	R11397,R11398	RC00049,RC02748	ko00000,ko01000	-	GH130	-	Glyco_hydro_130
CMS1_k127_2825953_3	497964.CfE428DRAFT_2312	1.047e-75	270.0	COG1082@1|root,COG1082@2|Bacteria,46UG0@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS1_k127_2825953_2	886293.Sinac_6944	1.563e-130	426.0	COG2755@1|root,COG2755@2|Bacteria,2IWSK@203682|Planctomycetes	203682|Planctomycetes	E	N-terminus of Esterase_SGNH_hydro-type	-	-	-	-	-	-	-	-	-	-	-	-	GxDLY,Lipase_GDSL_3
CMS1_k127_2825953_1	344747.PM8797T_23661	1.222e-132	432.0	COG1621@1|root,COG1621@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 32 family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,HTH_18
CMS1_k127_2828812_4	883126.HMPREF9710_00704	3.723e-07	62.0	COG5563@1|root,COG5563@2|Bacteria,1R9G5@1224|Proteobacteria,2VWW5@28216|Betaproteobacteria,477YT@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	HAF family	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
CMS1_k127_2828812_0	1210884.HG799463_gene9590	1.252e-14	87.0	COG3209@1|root,COG3209@2|Bacteria,2IY61@203682|Planctomycetes	203682|Planctomycetes	M	TIGRFAM RHS repeat-associated core domain	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,RHS_repeat
CMS1_k127_2828812_2	717606.PaecuDRAFT_1752	2.822e-10	73.0	COG3209@1|root,COG3209@2|Bacteria,1TR8F@1239|Firmicutes,4HBZE@91061|Bacilli,26RI4@186822|Paenibacillaceae	91061|Bacilli	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	PT-HINT,RHS_repeat,Thioesterase
CMS1_k127_2828812_3	1114964.L485_12650	5.73e-10	63.0	COG3039@1|root,COG3039@2|Bacteria,1MUVI@1224|Proteobacteria,2TSA7@28211|Alphaproteobacteria,2K0BK@204457|Sphingomonadales	204457|Sphingomonadales	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
CMS1_k127_2828812_1	439235.Dalk_2288	2.992e-11	75.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,42R71@68525|delta/epsilon subdivisions,2WMW5@28221|Deltaproteobacteria,2MPW6@213118|Desulfobacterales	28221|Deltaproteobacteria	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF4150,RHS,RHS_repeat,Transglut_core
CMS1_k127_283831_1	234267.Acid_2079	8.687e-54	200.0	COG1621@1|root,COG1621@2|Bacteria,3Y45X@57723|Acidobacteria	57723|Acidobacteria	G	Glycosyl hydrolase family 32	-	-	3.2.1.26,3.2.1.80	ko:K01193,ko:K03332	ko00051,ko00052,ko00500,ko01100,map00051,map00052,map00500,map01100	-	R00801,R00802,R00879,R02410,R03635,R03921,R06088	RC00028,RC00077	ko00000,ko00001,ko01000	-	GH32	-	Glyco_hydro_32C,Glyco_hydro_32N
CMS1_k127_283831_3	926561.KB900623_gene714	4.493e-15	79.0	COG0227@1|root,COG0227@2|Bacteria,1UH8Z@1239|Firmicutes,25PYQ@186801|Clostridia,3WC13@53433|Halanaerobiales	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
CMS1_k127_283831_0	891968.Anamo_1320	4.711e-90	308.0	COG0820@1|root,COG0820@2|Bacteria,3TAGW@508458|Synergistetes	508458|Synergistetes	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
CMS1_k127_283831_2	1114964.L485_12650	4.096e-18	89.0	COG3039@1|root,COG3039@2|Bacteria,1MUVI@1224|Proteobacteria,2TSA7@28211|Alphaproteobacteria,2K0BK@204457|Sphingomonadales	204457|Sphingomonadales	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
CMS1_k127_2854013_7	344747.PM8797T_11464	8.631e-14	80.0	COG1506@1|root,COG1506@2|Bacteria,2IYE5@203682|Planctomycetes	203682|Planctomycetes	E	COG1073 Hydrolases of the alpha beta superfamily	-	-	-	-	-	-	-	-	-	-	-	-	AXE1
CMS1_k127_2854013_0	1123242.JH636435_gene770	6.767e-104	350.0	COG0329@1|root,COG0329@2|Bacteria	2|Bacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
CMS1_k127_2854013_1	479434.Sthe_2712	1.781e-102	344.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	-	-	4.1.1.45	ko:K03392,ko:K07045	ko00380,ko01100,map00380,map01100	M00038	R04323	RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
CMS1_k127_2854013_2	1492738.FEM21_26700	7.85e-100	344.0	COG0591@1|root,COG0591@2|Bacteria,4NEN8@976|Bacteroidetes,1HYVB@117743|Flavobacteriia,2NYPU@237|Flavobacterium	976|Bacteroidetes	E	Sodium:solute symporter family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
CMS1_k127_2854013_4	1123242.JH636435_gene769	6.373e-80	280.0	2DBNR@1|root,2ZA54@2|Bacteria,2IYX9@203682|Planctomycetes	203682|Planctomycetes	S	Methane oxygenase PmoA	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
CMS1_k127_2854013_6	234267.Acid_7405	9.934e-39	155.0	COG2084@1|root,COG2084@2|Bacteria	2|Bacteria	I	phosphogluconate dehydrogenase (decarboxylating) activity	mmsB	-	1.1.1.31,1.1.1.60	ko:K00020,ko:K00042	ko00280,ko00630,ko01100,map00280,map00630,map01100	-	R01745,R01747,R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
CMS1_k127_2854013_5	1210884.HG799474_gene15081	3.635e-63	222.0	COG0693@1|root,COG0693@2|Bacteria,2IY0P@203682|Planctomycetes	203682|Planctomycetes	S	intracellular protease amidase	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
CMS1_k127_2854013_3	530564.Psta_1125	1.895e-94	316.0	COG2706@1|root,COG2706@2|Bacteria,2IY02@203682|Planctomycetes	203682|Planctomycetes	G	COG2706 3-carboxymuconate cyclase	-	-	3.1.1.31	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Lactonase
CMS1_k127_2860435_0	1173021.ALWA01000039_gene1858	2.157e-70	247.0	COG2843@1|root,COG2843@2|Bacteria,1G20Q@1117|Cyanobacteria	1117|Cyanobacteria	M	PFAM Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
CMS1_k127_2860435_1	1121481.AUAS01000025_gene2732	7.692e-07	59.0	COG3291@1|root,COG3386@1|root,COG5184@1|root,COG3291@2|Bacteria,COG3386@2|Bacteria,COG5184@2|Bacteria,4NDZC@976|Bacteroidetes,47RJR@768503|Cytophagia	976|Bacteroidetes	DZ	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,HYR,Laminin_G_3,PKD,SprB
CMS1_k127_2860435_2	1185876.BN8_05096	2.276e-06	59.0	28KQZ@1|root,2ZA8N@2|Bacteria,4NE6H@976|Bacteroidetes,47M1N@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2861094_4	309807.SRU_1362	4.882e-84	287.0	COG1137@1|root,COG1137@2|Bacteria,4NDUG@976|Bacteroidetes,1FIUP@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	ABC transporter	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
CMS1_k127_2861094_5	1303518.CCALI_00993	3.237e-62	230.0	COG0455@1|root,COG0455@2|Bacteria	2|Bacteria	D	bacterial-type flagellum organization	flhG	-	-	ko:K02282,ko:K04562	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,CbiA,ParA
CMS1_k127_2861094_7	1009370.ALO_14172	1.619e-54	210.0	COG1419@1|root,COG1419@2|Bacteria,1TSP7@1239|Firmicutes,4H2XV@909932|Negativicutes	909932|Negativicutes	N	Flagellar biosynthesis	flhF	-	-	ko:K02404	-	-	-	-	ko00000,ko02035	-	-	-	SRP54
CMS1_k127_2861094_13	1499967.BAYZ01000068_gene1935	0.0007233	52.0	COG3266@1|root,COG3420@1|root,COG4733@1|root,COG3266@2|Bacteria,COG3420@2|Bacteria,COG4733@2|Bacteria,2NS5M@2323|unclassified Bacteria	2|Bacteria	P	Fibronectin type 3 domain	-	-	-	ko:K12685,ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000,ko02044	1.B.12.5.1,1.B.12.5.3,3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CHB_HEX_C_1,CHU_C,DUF1573,DUF285,F5_F8_type_C,Laminin_G_3,Lectin_legB,fn3
CMS1_k127_2861094_8	330214.NIDE2388	5.529e-36	159.0	29R89@1|root,30C9N@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2861094_10	1242864.D187_006671	2.746e-14	88.0	COG1572@1|root,COG1572@2|Bacteria,1QX45@1224|Proteobacteria,42YA1@68525|delta/epsilon subdivisions,2WTP9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	HYR,Kelch_4,PQQ_2,VCBS
CMS1_k127_2861094_9	1121405.dsmv_2480	1.865e-19	94.0	COG1321@1|root,COG1321@2|Bacteria,1RH2Z@1224|Proteobacteria,42U02@68525|delta/epsilon subdivisions,2X6HI@28221|Deltaproteobacteria,2MQ1G@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Helix-turn-helix diphteria tox regulatory element	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress
CMS1_k127_2861094_11	439235.Dalk_3438	7.643e-14	82.0	COG0755@1|root,COG0755@2|Bacteria,1RCCI@1224|Proteobacteria,42PVM@68525|delta/epsilon subdivisions,2WJ7I@28221|Deltaproteobacteria,2MHT7@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Cytochrome c assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
CMS1_k127_2861094_2	1125863.JAFN01000001_gene1123	1.058e-99	342.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,42MUG@68525|delta/epsilon subdivisions,2WISB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
CMS1_k127_2861094_3	1262915.BN574_00038	1.732e-88	303.0	COG0181@1|root,COG0181@2|Bacteria,1TPFQ@1239|Firmicutes,4H1XA@909932|Negativicutes	909932|Negativicutes	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
CMS1_k127_2861094_0	335543.Sfum_3201	1.333e-145	488.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,1MUI0@1224|Proteobacteria,42MCB@68525|delta/epsilon subdivisions,2WIRJ@28221|Deltaproteobacteria,2MQX4@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Belongs to the precorrin methyltransferase family	hemD	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
CMS1_k127_2861094_1	1210884.HG799468_gene13649	5.996e-126	411.0	COG0113@1|root,COG0113@2|Bacteria,2IWU8@203682|Planctomycetes	203682|Planctomycetes	H	Belongs to the ALAD family	-	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
CMS1_k127_2861094_12	452637.Oter_1870	3.98e-08	62.0	29AYY@1|root,2ZXXY@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2861094_6	1078083.HMPREF1208_01884	6.562e-59	214.0	COG0717@1|root,COG0717@2|Bacteria,1V1BE@1239|Firmicutes,4HGR4@91061|Bacilli,4GYTC@90964|Staphylococcaceae	91061|Bacilli	F	Belongs to the dCTP deaminase family	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
CMS1_k127_2863582_0	118168.MC7420_5234	1.817e-67	246.0	COG5563@1|root,COG5563@2|Bacteria,1GIA8@1117|Cyanobacteria,1HFHC@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2863582_2	497964.CfE428DRAFT_4864	8.17e-49	184.0	COG1595@1|root,COG1595@2|Bacteria,46VE8@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2863582_1	631362.Thi970DRAFT_04309	1.158e-54	203.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,1RR36@1236|Gammaproteobacteria,1WYS8@135613|Chromatiales	135613|Chromatiales	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	CHASE2,HAMP,HEAT_2,Pkinase,sCache_3_2
CMS1_k127_2865110_20	1304284.L21TH_0927	8.283e-52	186.0	COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,24HD9@186801|Clostridia,36HZ3@31979|Clostridiaceae	186801|Clostridia	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
CMS1_k127_2865110_22	290397.Adeh_3371	3.925e-43	161.0	COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,42SVI@68525|delta/epsilon subdivisions,2WP7T@28221|Deltaproteobacteria,2YV9P@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
CMS1_k127_2865110_5	215803.DB30_8120	9.323e-162	521.0	COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,42MET@68525|delta/epsilon subdivisions,2WITH@28221|Deltaproteobacteria,2YUC2@29|Myxococcales	28221|Deltaproteobacteria	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	algC	-	5.4.2.2,5.4.2.8	ko:K01840,ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
CMS1_k127_2865110_1	655815.ZPR_1376	6.728e-198	644.0	COG3534@1|root,COG3534@2|Bacteria,4NHR5@976|Bacteroidetes	976|Bacteroidetes	G	Alpha-L-arabinofuranosidase C-terminal domain	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
CMS1_k127_2865110_2	1303518.CCALI_00042	5.513e-181	576.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2,Sulfatase
CMS1_k127_2865110_12	697281.Mahau_1213	1.037e-108	358.0	COG1082@1|root,COG1082@2|Bacteria,1TRUN@1239|Firmicutes	1239|Firmicutes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS1_k127_2865110_8	697281.Mahau_1212	3.322e-141	456.0	COG0673@1|root,COG0673@2|Bacteria,1VRY8@1239|Firmicutes,24PM0@186801|Clostridia	186801|Clostridia	S	COGs COG0673 dehydrogenase and related protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_2865110_30	1439940.BAY1663_03730	8.356e-05	55.0	COG0642@1|root,COG0642@2|Bacteria,1MURQ@1224|Proteobacteria,1RP9C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	fleS	-	2.7.13.3	ko:K10942	ko02020,ko05111,map02020,map05111	M00515	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS_8
CMS1_k127_2865110_16	370438.PTH_0393	4.119e-83	291.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,24862@186801|Clostridia,261AB@186807|Peptococcaceae	186801|Clostridia	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
CMS1_k127_2865110_24	1519464.HY22_10980	2.63e-38	155.0	COG1091@1|root,COG1091@2|Bacteria,1FEDX@1090|Chlorobi	1090|Chlorobi	M	Polysaccharide biosynthesis protein	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
CMS1_k127_2865110_26	215803.DB30_5213	7.706e-10	70.0	COG1409@1|root,COG3291@1|root,COG1409@2|Bacteria,COG3291@2|Bacteria,1N85S@1224|Proteobacteria,42WZ6@68525|delta/epsilon subdivisions,2XA07@28221|Deltaproteobacteria,2YZHM@29|Myxococcales	28221|Deltaproteobacteria	S	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,PKD
CMS1_k127_2865110_21	247490.KSU1_D0243	8.788e-52	201.0	28HQ3@1|root,2Z7XW@2|Bacteria,2J224@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF2851)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2851
CMS1_k127_2865110_13	661478.OP10G_4641	3.67e-108	370.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	ydgJ	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0070401,GO:0070402,GO:0097159,GO:0102497,GO:1901265,GO:1901363	1.1.1.371	ko:K16044	ko00562,ko01120,map00562,map01120	-	R09954	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_2865110_19	435591.BDI_1325	6.385e-56	217.0	COG3533@1|root,COG3533@2|Bacteria,4NFW3@976|Bacteroidetes,2FRKH@200643|Bacteroidia,22Z9V@171551|Porphyromonadaceae	976|Bacteroidetes	S	Beta-L-arabinofuranosidase, GH127	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
CMS1_k127_2865110_14	1121012.AUKX01000029_gene941	8.953e-108	361.0	COG4409@1|root,COG4409@2|Bacteria,4PKIP@976|Bacteroidetes,1IJA8@117743|Flavobacteriia,23HZ9@178469|Arenibacter	976|Bacteroidetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
CMS1_k127_2865110_18	237368.SCABRO_02780	5.984e-60	214.0	COG0138@1|root,COG0138@2|Bacteria,2IXB5@203682|Planctomycetes	203682|Planctomycetes	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
CMS1_k127_2865110_4	1125863.JAFN01000001_gene568	1.811e-163	524.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,42MCI@68525|delta/epsilon subdivisions,2WJ7H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC,GARS_A,GARS_C,GARS_N
CMS1_k127_2865110_23	717231.Flexsi_2012	1.726e-40	163.0	COG2199@1|root,COG3706@2|Bacteria,2GGAA@200930|Deferribacteres	200930|Deferribacteres	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
CMS1_k127_2865110_25	670487.Ocepr_1304	1.35e-18	91.0	COG0848@1|root,COG0848@2|Bacteria,1WKN6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	U	PFAM Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
CMS1_k127_2865110_10	273068.TTE0337	7.112e-119	396.0	COG1486@1|root,COG1486@2|Bacteria,1TQ9I@1239|Firmicutes,24995@186801|Clostridia,42FX4@68295|Thermoanaerobacterales	186801|Clostridia	G	PFAM glycoside hydrolase, family 4	-	-	3.2.1.86	ko:K01222	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT4	-	Glyco_hydro_4,Glyco_hydro_4C
CMS1_k127_2865110_11	1123242.JH636434_gene4773	1.577e-111	368.0	COG0152@1|root,COG0152@2|Bacteria,2IY7D@203682|Planctomycetes	203682|Planctomycetes	F	SAICAR synthetase	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
CMS1_k127_2865110_3	243231.GSU1636	5.162e-171	550.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,42MDB@68525|delta/epsilon subdivisions,2WITV@28221|Deltaproteobacteria,43UES@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
CMS1_k127_2865110_15	1121946.AUAX01000022_gene3840	3.661e-83	284.0	2DBF0@1|root,2Z8VT@2|Bacteria,2I88D@201174|Actinobacteria,4DIBF@85008|Micromonosporales	201174|Actinobacteria	S	3-oxo-5-alpha-steroid 4-dehydrogenase	-	-	1.3.1.22	ko:K12343	ko00140,map00140	-	R02208,R02497,R08954,R10242	RC00145	ko00000,ko00001,ko01000	-	-	-	Steroid_dh
CMS1_k127_2865110_17	391625.PPSIR1_16360	3.116e-74	262.0	COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,42NJT@68525|delta/epsilon subdivisions,2WM7E@28221|Deltaproteobacteria,2YXN2@29|Myxococcales	28221|Deltaproteobacteria	GM	epimerase dehydratase	hpnA	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
CMS1_k127_2865110_0	401526.TcarDRAFT_1596	6.145e-207	664.0	COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,4H236@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
CMS1_k127_2865110_6	457429.ABJI02000040_gene3859	4.342e-153	500.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
CMS1_k127_2865110_7	1167006.UWK_00552	3.128e-143	471.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,42MA7@68525|delta/epsilon subdivisions,2WMKZ@28221|Deltaproteobacteria,2MJ0R@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Acts as a magnesium transporter	-	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
CMS1_k127_2865110_28	356851.JOAN01000010_gene4709	5.607e-07	57.0	COG0139@1|root,COG0139@2|Bacteria,2IKKU@201174|Actinobacteria,4DDD9@85008|Micromonosporales	201174|Actinobacteria	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	GO:0008150,GO:0040007	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1606	PRA-CH
CMS1_k127_2865110_29	525904.Tter_0988	4.427e-06	54.0	COG1708@1|root,COG1708@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	linF	-	-	ko:K18236	-	-	-	-	ko00000,ko01504	-	-	-	Adenyl_transf,DUF4037,NTP_transf_2
CMS1_k127_2865110_9	1303518.CCALI_00762	1.197e-132	437.0	28I74@1|root,2Z8A0@2|Bacteria	2|Bacteria	S	COG NOG26804 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2867763_1	1235803.C825_02381	7.978e-79	293.0	COG0823@1|root,COG0823@2|Bacteria,4NIGD@976|Bacteroidetes,2G2P7@200643|Bacteroidia	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2867763_0	1288963.ADIS_1774	4.714e-94	327.0	COG3356@1|root,COG3356@2|Bacteria,4NHP6@976|Bacteroidetes	976|Bacteroidetes	S	PFAM Neutral alkaline nonlysosomal ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2867763_2	1235803.C825_04045	2.011e-14	86.0	2DZRA@1|root,32VGT@2|Bacteria,4NW08@976|Bacteroidetes,2FWST@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2870966_0	926569.ANT_08110	1.804e-114	378.0	COG1940@1|root,COG1940@2|Bacteria	2|Bacteria	GK	ROK family	-	-	2.7.1.188,2.7.1.2,2.7.1.214,2.7.1.60,5.1.3.9	ko:K00845,ko:K13967,ko:K19979,ko:K20433	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko00525,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map00525,map01100,map01110,map01120,map01130,map01200	M00001,M00549,M00814,M00815	R00299,R01600,R01786,R02087,R02705,R11185,R11234	RC00002,RC00017,RC00290	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
CMS1_k127_2870966_2	635013.TherJR_1892	9.219e-60	226.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS1_k127_2870966_1	1122173.AXVL01000011_gene1628	5.747e-79	271.0	COG1968@1|root,COG1968@2|Bacteria,378JX@32066|Fusobacteria	32066|Fusobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
CMS1_k127_2871273_0	1227739.Hsw_4145	2.997e-135	469.0	COG2304@1|root,COG2304@2|Bacteria,4NFX3@976|Bacteroidetes,47KQ9@768503|Cytophagia	976|Bacteroidetes	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	CarbopepD_reg_2,DUF3520,VWA,vWF_A
CMS1_k127_2871273_1	595460.RRSWK_06391	1.502e-08	58.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_2874057_1	595460.RRSWK_02262	6.463e-09	58.0	COG5492@1|root,COG5492@2|Bacteria,2IXP9@203682|Planctomycetes	203682|Planctomycetes	N	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt2,PSD1
CMS1_k127_2874057_0	886293.Sinac_1517	3.803e-114	401.0	COG2010@1|root,COG2319@1|root,COG2010@2|Bacteria,COG2319@2|Bacteria,2IXWG@203682|Planctomycetes	203682|Planctomycetes	C	WD-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,WD40
CMS1_k127_2881406_3	883080.HMPREF9697_00191	1.782e-17	84.0	COG2128@1|root,COG2128@2|Bacteria,1RAJ4@1224|Proteobacteria,2U65F@28211|Alphaproteobacteria,3K0HV@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS1_k127_2881406_5	886293.Sinac_4705	3.314e-06	59.0	COG2834@1|root,COG2834@2|Bacteria,2J4MG@203682|Planctomycetes	203682|Planctomycetes	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2881406_1	1047013.AQSP01000076_gene1467	1.829e-30	127.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_2881406_2	886293.Sinac_2787	7.944e-18	99.0	COG1595@1|root,COG1595@2|Bacteria,2IYTY@203682|Planctomycetes	203682|Planctomycetes	K	Protein of unknown function (DUF1559)	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_10,Sigma70_r2,Sigma70_r4_2
CMS1_k127_2881406_4	1200792.AKYF01000026_gene163	5.974e-15	90.0	COG4932@1|root,COG4932@2|Bacteria,1UJQY@1239|Firmicutes,4ITDJ@91061|Bacilli,270X3@186822|Paenibacillaceae	91061|Bacilli	M	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS1_k127_2881406_0	1122931.AUAE01000001_gene619	2.173e-135	438.0	COG3669@1|root,COG3669@2|Bacteria	2|Bacteria	G	Alpha-L-fucosidase	-	-	-	-	-	-	-	-	-	-	-	-	Alpha_L_fucos
CMS1_k127_2881406_6	1122931.AUAE01000014_gene2000	0.000213	46.0	COG1621@1|root,COG1621@2|Bacteria,4NJ89@976|Bacteroidetes,2FRQN@200643|Bacteroidia	976|Bacteroidetes	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_288862_0	935948.KE386495_gene1292	3.111e-76	281.0	COG1175@1|root,COG1175@2|Bacteria,1TPTZ@1239|Firmicutes,2492R@186801|Clostridia,42JBI@68295|Thermoanaerobacterales	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_2900299_2	1242864.D187_007073	7.087e-08	61.0	COG3385@1|root,COG3385@2|Bacteria,1RK5C@1224|Proteobacteria,43CJU@68525|delta/epsilon subdivisions,2X7U7@28221|Deltaproteobacteria,2Z16K@29|Myxococcales	28221|Deltaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
CMS1_k127_2900299_0	517417.Cpar_1613	4.367e-45	169.0	COG0634@1|root,COG0634@2|Bacteria,1FE2X@1090|Chlorobi	1090|Chlorobi	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
CMS1_k127_2900299_1	1304880.JAGB01000002_gene2320	1.014e-21	100.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,248TY@186801|Clostridia	186801|Clostridia	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
CMS1_k127_2900860_3	247490.KSU1_C1333	1.272e-18	96.0	COG4968@1|root,COG4968@2|Bacteria,2J519@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CMS1_k127_2900860_2	1121440.AUMA01000016_gene174	1.923e-19	99.0	COG2159@1|root,COG2159@2|Bacteria,1R8EW@1224|Proteobacteria,42Z71@68525|delta/epsilon subdivisions,2X085@28221|Deltaproteobacteria,2MB5X@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CMS1_k127_2900860_0	211165.AJLN01000104_gene6535	4.398e-89	305.0	COG0531@1|root,COG0531@2|Bacteria,1G2GM@1117|Cyanobacteria,1JHRW@1189|Stigonemataceae	1117|Cyanobacteria	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
CMS1_k127_2908884_3	797209.ZOD2009_16563	2.821e-21	97.0	arCOG00516@1|root,arCOG00516@2157|Archaea,2XXT7@28890|Euryarchaeota,23WEB@183963|Halobacteria	183963|Halobacteria	S	flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
CMS1_k127_2908884_1	240015.ACP_0916	4.958e-139	465.0	COG3292@1|root,COG4447@1|root,COG3292@2|Bacteria,COG4447@2|Bacteria,3Y3Y6@57723|Acidobacteria,2JI5Y@204432|Acidobacteriia	204432|Acidobacteriia	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	BNR,Sortilin-Vps10
CMS1_k127_2908884_2	644282.Deba_1149	3.31e-22	108.0	2BCS0@1|root,303C3@2|Bacteria,1N7SU@1224|Proteobacteria,42WF2@68525|delta/epsilon subdivisions,2WR6I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Gcw_chp
CMS1_k127_2908884_0	589865.DaAHT2_0128	1.147e-174	560.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,42M8M@68525|delta/epsilon subdivisions,2WJE2@28221|Deltaproteobacteria,2MISS@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Ammonium Transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
CMS1_k127_2910145_3	627192.SLG_32260	5.76e-18	92.0	2DXIC@1|root,34552@2|Bacteria,1P1XF@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2910145_1	1121104.AQXH01000001_gene1395	1.644e-47	184.0	COG0739@1|root,COG0739@2|Bacteria,4NPNT@976|Bacteroidetes	976|Bacteroidetes	M	peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CMS1_k127_2910145_0	234267.Acid_2605	5.864e-75	260.0	COG2133@1|root,COG2133@2|Bacteria,3Y3FI@57723|Acidobacteria	57723|Acidobacteria	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CMS1_k127_2910145_2	240016.ABIZ01000001_gene4411	2.2e-21	99.0	COG2755@1|root,COG2755@2|Bacteria,46S6X@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Acyl-CoA thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS1_k127_2912015_0	926561.KB900619_gene2441	1.06e-69	243.0	COG2206@1|root,COG2206@2|Bacteria,1TS2E@1239|Firmicutes,249S8@186801|Clostridia,3WB2V@53433|Halanaerobiales	186801|Clostridia	T	PFAM HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
CMS1_k127_2912015_1	247490.KSU1_C1333	5.891e-16	89.0	COG4968@1|root,COG4968@2|Bacteria,2J519@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CMS1_k127_2912015_3	68570.DC74_3577	0.0006879	45.0	COG1874@1|root,COG1874@2|Bacteria,2GMDT@201174|Actinobacteria	201174|Actinobacteria	G	Beta-galactosidase	bga2	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
CMS1_k127_291310_0	1380600.AUYN01000001_gene2799	1.598e-200	653.0	COG3540@1|root,COG3540@2|Bacteria,4NFXQ@976|Bacteroidetes,1HY2S@117743|Flavobacteriia	976|Bacteroidetes	P	PhoD-like phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	PhoD
CMS1_k127_291310_1	1128421.JAGA01000004_gene2618	1.265e-133	436.0	COG0183@1|root,COG0183@2|Bacteria,2NNU9@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the thiolase family	fadA	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
CMS1_k127_291310_2	644282.Deba_1863	9.552e-127	419.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42MI5@68525|delta/epsilon subdivisions,2WITQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	3-hydroxyacyl-CoA dehydrogenase	-	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1,ECH_2
CMS1_k127_2914349_2	305900.GV64_20360	1.438e-111	370.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,1RMVY@1236|Gammaproteobacteria,1XIU3@135619|Oceanospirillales	135619|Oceanospirillales	G	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	-	-	-	-	-	-	-	-	-	-	PFK
CMS1_k127_2914349_8	452637.Oter_2229	4.698e-20	106.0	COG2273@1|root,COG2273@2|Bacteria	2|Bacteria	G	xyloglucan:xyloglucosyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Glyco_hydro_16,Glyco_transf_25,Malectin,Ricin_B_lectin,Trans_reg_C,Trypsin,VCBS
CMS1_k127_2914349_3	1303518.CCALI_01617	1.27e-88	319.0	COG3934@1|root,COG3934@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.4	ko:K01179,ko:K13276	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	GH5,GH9	-	Cellulase,Glyco_hydro_42
CMS1_k127_2914349_4	439235.Dalk_3414	1.487e-87	310.0	COG1538@1|root,COG1538@2|Bacteria,1QFYM@1224|Proteobacteria,42RBK@68525|delta/epsilon subdivisions,2WMSG@28221|Deltaproteobacteria,2MJM2@213118|Desulfobacterales	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
CMS1_k127_2914349_0	439235.Dalk_3415	0.0	1166.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJN5@28221|Deltaproteobacteria,2MMWB@213118|Desulfobacterales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
CMS1_k127_2914349_1	439235.Dalk_3416	2.273e-114	385.0	COG0845@1|root,COG0845@2|Bacteria,1PEVY@1224|Proteobacteria,42ZAR@68525|delta/epsilon subdivisions,2WU8I@28221|Deltaproteobacteria,2MN1D@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3
CMS1_k127_2914349_6	1167006.UWK_00819	6.841e-25	110.0	COG1846@1|root,COG1846@2|Bacteria,1Q2ZA@1224|Proteobacteria,43DY3@68525|delta/epsilon subdivisions,2X9D2@28221|Deltaproteobacteria,2MNY4@213118|Desulfobacterales	28221|Deltaproteobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
CMS1_k127_2914349_12	994479.GL877878_gene1203	6.955e-06	58.0	COG0454@1|root,COG0456@2|Bacteria,2I9J6@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,FR47
CMS1_k127_2914349_13	338966.Ppro_3337	4.114e-05	55.0	COG0457@1|root,COG0457@2|Bacteria	338966.Ppro_3337|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2914349_7	1121428.DESHY_40024___1	5.696e-22	104.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,24HHW@186801|Clostridia,261SF@186807|Peptococcaceae	186801|Clostridia	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
CMS1_k127_2914349_5	517418.Ctha_0783	2.592e-28	126.0	COG0705@1|root,COG0705@2|Bacteria,1FDF1@1090|Chlorobi	1090|Chlorobi	S	PFAM Rhomboid family protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
CMS1_k127_2914349_11	1501269.EW15_0209	8.6e-09	61.0	COG0484@1|root,COG0484@2|Bacteria,1G2FB@1117|Cyanobacteria,1MMFK@1212|Prochloraceae	1117|Cyanobacteria	O	heat shock protein DnaJ	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ
CMS1_k127_2914349_10	521674.Plim_2057	8.754e-13	74.0	COG1366@1|root,COG1366@2|Bacteria,2J02R@203682|Planctomycetes	203682|Planctomycetes	T	Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor)	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
CMS1_k127_2914349_9	1121104.AQXH01000001_gene1657	3.975e-13	76.0	COG2172@1|root,COG2172@2|Bacteria,4NRAA@976|Bacteroidetes	976|Bacteroidetes	T	Pfam Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	rsbW	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
CMS1_k127_292498_4	1510531.JQJJ01000010_gene1865	0.0006046	45.0	COG1309@1|root,COG1309@2|Bacteria,1RARJ@1224|Proteobacteria,2UAVR@28211|Alphaproteobacteria,3K5ZY@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	BetI-type transcriptional repressor, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
CMS1_k127_292498_1	1174528.JH992898_gene3360	1.366e-50	193.0	COG0515@1|root,COG5263@1|root,COG0515@2|Bacteria,COG5263@2|Bacteria,1FZWQ@1117|Cyanobacteria,1JI7C@1189|Stigonemataceae	1117|Cyanobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	MORN,Pkinase,WG_beta_rep
CMS1_k127_292498_3	977880.pRALTA_0086	0.0004827	44.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,2VNU5@28216|Betaproteobacteria,1K1AA@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
CMS1_k127_292498_0	378806.STAUR_3925	1.225e-190	608.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,42Y93@68525|delta/epsilon subdivisions,2WU1Y@28221|Deltaproteobacteria,2YWK2@29|Myxococcales	28221|Deltaproteobacteria	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
CMS1_k127_292498_2	1123252.ATZF01000027_gene1612	3.788e-11	67.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	SBBP
CMS1_k127_2928558_0	756272.Plabr_3820	1.749e-161	527.0	COG2931@1|root,COG2931@2|Bacteria,2J53M@203682|Planctomycetes	203682|Planctomycetes	C	Animal haem peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	An_peroxidase
CMS1_k127_2931483_7	1210884.HG799464_gene10455	1.131e-54	198.0	COG1051@1|root,COG1051@2|Bacteria,2J1PQ@203682|Planctomycetes	203682|Planctomycetes	F	NUDIX domain	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
CMS1_k127_2931483_5	484770.UFO1_0427	2.241e-75	258.0	COG1272@1|root,COG1272@2|Bacteria,1TSFK@1239|Firmicutes,4H41C@909932|Negativicutes	909932|Negativicutes	S	channel protein, hemolysin III family	yqfA	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
CMS1_k127_2931483_0	926561.KB900619_gene2526	9.625e-251	800.0	COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,248GI@186801|Clostridia,3WA7U@53433|Halanaerobiales	186801|Clostridia	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
CMS1_k127_2931483_4	1123368.AUIS01000028_gene1327	1.112e-87	295.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RR3R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	(ABC) transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_2931483_2	102125.Xen7305DRAFT_00025570	9.185e-170	561.0	COG0577@1|root,COG0577@2|Bacteria,1G0Z7@1117|Cyanobacteria,3VM1W@52604|Pleurocapsales	1117|Cyanobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS1_k127_2931483_6	32049.SYNPCC7002_A1483	1.727e-56	214.0	COG0845@1|root,COG0845@2|Bacteria,1G29R@1117|Cyanobacteria,1H05T@1129|Synechococcus	1117|Cyanobacteria	M	Efflux transporter, RND family, MFP subunit	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3
CMS1_k127_2931483_1	1173028.ANKO01000115_gene5817	1.232e-185	606.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,1GBVH@1117|Cyanobacteria,1HEBG@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
CMS1_k127_2931483_13	743719.PaelaDRAFT_4656	1.444e-21	99.0	COG3682@1|root,COG3682@2|Bacteria,1V7EY@1239|Firmicutes,4HP8S@91061|Bacilli,276QV@186822|Paenibacillaceae	91061|Bacilli	K	Penicillinase repressor	copY	-	-	ko:K02171	ko01501,map01501	M00627	-	-	ko00000,ko00001,ko00002,ko01504,ko03000	-	-	-	Penicillinase_R
CMS1_k127_2931483_10	794903.OPIT5_29480	1.019e-25	124.0	COG0526@1|root,COG2373@1|root,COG4219@1|root,COG0526@2|Bacteria,COG2373@2|Bacteria,COG4219@2|Bacteria,46XN8@74201|Verrucomicrobia,3K9XB@414999|Opitutae	414999|Opitutae	KT	BlaR1 peptidase M56	-	-	-	ko:K02172	ko01501,map01501	M00627	-	-	ko00000,ko00001,ko00002,ko01002,ko01504	-	-	-	Peptidase_M56
CMS1_k127_2931483_14	886293.Sinac_4894	1.26e-11	78.0	COG1595@1|root,COG1595@2|Bacteria,2J3UT@203682|Planctomycetes	203682|Planctomycetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_2931483_15	886293.Sinac_4894	2.404e-11	70.0	COG1595@1|root,COG1595@2|Bacteria,2J3UT@203682|Planctomycetes	203682|Planctomycetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_2931483_12	498761.HM1_1863	1.289e-21	103.0	COG1959@1|root,COG1959@2|Bacteria,1V3QB@1239|Firmicutes,24JIV@186801|Clostridia	186801|Clostridia	K	transcriptional regulator	iscR	-	-	-	-	-	-	-	-	-	-	-	Rrf2
CMS1_k127_2931483_11	706587.Desti_0283	9.877e-25	108.0	COG0745@1|root,COG0745@2|Bacteria,1NBQZ@1224|Proteobacteria,42V8P@68525|delta/epsilon subdivisions,2WS87@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS1_k127_2931483_9	1089553.Tph_c13460	7.101e-29	123.0	COG2110@1|root,COG2110@2|Bacteria,1TPCU@1239|Firmicutes,24ARG@186801|Clostridia,42GU1@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM Appr-1-p processing domain protein	ymdB	-	-	-	-	-	-	-	-	-	-	-	Macro
CMS1_k127_2931483_8	706587.Desti_0285	7.131e-43	166.0	COG2181@1|root,COG2181@2|Bacteria	2|Bacteria	C	nitrate reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	SLAC1
CMS1_k127_2931483_3	246194.CHY_2406	1.067e-105	355.0	COG0247@1|root,COG0247@2|Bacteria,1UZQ0@1239|Firmicutes,24E5H@186801|Clostridia,42F8Q@68295|Thermoanaerobacterales	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_17
CMS1_k127_2953986_2	401526.TcarDRAFT_0127	6.019e-35	139.0	COG0245@1|root,COG1211@1|root,COG0245@2|Bacteria,COG1211@2|Bacteria,1V3P0@1239|Firmicutes,4H2VG@909932|Negativicutes	909932|Negativicutes	H	Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
CMS1_k127_2953986_1	1122927.KB895433_gene209	1.046e-76	271.0	COG4956@1|root,COG4956@2|Bacteria,1TP0P@1239|Firmicutes,4H9NQ@91061|Bacilli,26R3P@186822|Paenibacillaceae	91061|Bacilli	S	Twitching motility protein PilT	yacL	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	TRAM
CMS1_k127_2953986_4	1123284.KB899044_gene715	1.526e-17	93.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,4HABP@91061|Bacilli,26P9M@186821|Sporolactobacillaceae	91061|Bacilli	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1,2.4.2.28	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	M00034	R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
CMS1_k127_2953986_5	485916.Dtox_1088	3.59e-15	81.0	COG1872@1|root,COG1872@2|Bacteria,1VFSH@1239|Firmicutes,24T87@186801|Clostridia,262RJ@186807|Peptococcaceae	186801|Clostridia	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
CMS1_k127_2953986_0	653733.Selin_2042	3.912e-87	298.0	COG0825@1|root,COG0825@2|Bacteria	2|Bacteria	I	malonyl-CoA biosynthetic process	accA	-	2.1.3.15,6.4.1.2	ko:K01962,ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.accA	ACCA
CMS1_k127_2953986_3	234267.Acid_0845	2.606e-20	106.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	cpeZ	-	-	ko:K05384,ko:K05386	ko00196,ko01100,map00196,map01100	-	-	-	ko00000,ko00001,ko00194	-	-	-	HEAT_2
CMS1_k127_2974424_0	1463926.JOCA01000001_gene4380	6.038e-77	282.0	COG0515@1|root,COG0515@2|Bacteria	1463926.JOCA01000001_gene4380|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2974424_1	794903.OPIT5_16845	3.93e-68	266.0	2DZRA@1|root,32VGT@2|Bacteria,46WB0@74201|Verrucomicrobia,3K8WK@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2974424_8	1120949.KB903302_gene6610	2.731e-12	82.0	COG4409@1|root,COG4409@2|Bacteria,2IHE6@201174|Actinobacteria,4DFME@85008|Micromonosporales	201174|Actinobacteria	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
CMS1_k127_2974424_7	452637.Oter_2229	7.672e-14	87.0	COG2273@1|root,COG2273@2|Bacteria	2|Bacteria	G	xyloglucan:xyloglucosyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Glyco_hydro_16,Glyco_transf_25,Malectin,Ricin_B_lectin,Trans_reg_C,Trypsin,VCBS
CMS1_k127_2974424_4	935948.KE386495_gene1438	6.929e-42	173.0	COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,24A0P@186801|Clostridia,42G4U@68295|Thermoanaerobacterales	186801|Clostridia	O	PFAM Peptidase M22, glycoprotease	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Acetyltransf_1,Peptidase_M22
CMS1_k127_2974424_6	935948.KE386495_gene1437	4.967e-37	147.0	COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,24J9Z@186801|Clostridia,42G5T@68295|Thermoanaerobacterales	186801|Clostridia	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
CMS1_k127_2974424_2	858215.Thexy_2211	4.075e-60	236.0	COG4354@1|root,COG4354@2|Bacteria,1TR78@1239|Firmicutes,25K1B@186801|Clostridia,42ITY@68295|Thermoanaerobacterales	186801|Clostridia	G	beta-glucosidase 2, glycosyl-hydrolase family 116 N-term	-	-	3.2.1.45	ko:K17108	ko00511,ko00600,ko01100,map00511,map00600,map01100	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH116	-	DUF608,Glyco_hydr_116N
CMS1_k127_2974424_5	1123507.ATVQ01000002_gene348	1.204e-38	151.0	COG0237@1|root,COG0237@2|Bacteria,2GN96@201174|Actinobacteria,1W8VX@1268|Micrococcaceae	201174|Actinobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE,GrpB
CMS1_k127_2974424_3	1340493.JNIF01000004_gene245	8.049e-53	194.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Calx-beta,CarboxypepD_reg,DUF1080,F5_F8_type_C,G5,G8,Glyco_hyd_101C,Glyco_hydro_101,Trypsin_2,YSIRK_signal,fn3
CMS1_k127_2984078_1	370438.PTH_1249	3.747e-49	177.0	COG5405@1|root,COG5405@2|Bacteria,1TPXK@1239|Firmicutes,24FS4@186801|Clostridia,261JH@186807|Peptococcaceae	186801|Clostridia	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
CMS1_k127_2984078_0	243231.GSU2085	1.427e-69	248.0	COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,42MBC@68525|delta/epsilon subdivisions,2WIKU@28221|Deltaproteobacteria,43TN4@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the phosphorylation of D-glycero-D-manno- heptose 7-phosphate at the C-1 position to selectively form D- glycero-beta-D-manno-heptose-1,7-bisphosphate	hldE	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iAF987.Gmet_0922	CTP_transf_like,PfkB
CMS1_k127_2990131_1	1303518.CCALI_00913	2.483e-16	91.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02679	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
CMS1_k127_2990131_2	9713.XP_006738384.1	1.07e-06	57.0	COG0666@1|root,KOG0504@2759|Eukaryota,38CSH@33154|Opisthokonta,3BBUK@33208|Metazoa,3CWPM@33213|Bilateria,4824P@7711|Chordata,497A7@7742|Vertebrata,3J8RI@40674|Mammalia,3EGCZ@33554|Carnivora	33208|Metazoa	S	ankyrin repeat and	ANKS4B	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0005886,GO:0005902,GO:0005903,GO:0006950,GO:0008104,GO:0008150,GO:0009987,GO:0012505,GO:0016020,GO:0016043,GO:0022607,GO:0031984,GO:0033036,GO:0033554,GO:0034622,GO:0034976,GO:0042175,GO:0042995,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0050896,GO:0051179,GO:0051716,GO:0065003,GO:0071840,GO:0071944,GO:0098827,GO:0098858,GO:0098862,GO:0120025,GO:1904106,GO:1904970	-	ko:K21414,ko:K21878	-	-	-	-	ko00000,ko03036,ko04131	-	-	-	Ank_2,Ank_4,SAM_1
CMS1_k127_2990131_0	886293.Sinac_3826	7.131e-255	811.0	COG3518@1|root,COG3518@2|Bacteria,2J26H@203682|Planctomycetes	203682|Planctomycetes	S	anti-sigma factor antagonist activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2993858_0	880073.Calab_1754	4.402e-134	445.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,2NQ6Y@2323|unclassified Bacteria	2|Bacteria	M	PKD domain	-	-	3.2.1.4,3.4.21.66	ko:K01179,ko:K08651	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	GH5,GH9	-	Autotransporter,PKD,Peptidase_S8,Peptidase_S8_N,fn3
CMS1_k127_2996487_4	903818.KI912268_gene1464	5.238e-06	51.0	COG0642@1|root,COG2205@2|Bacteria	903818.KI912268_gene1464|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2996487_0	903818.KI912268_gene1463	0.0	1009.0	COG1034@1|root,COG4624@1|root,COG1034@2|Bacteria,COG4624@2|Bacteria	2|Bacteria	C	iron-sulfur cluster assembly	nuoG	-	1.12.1.2,1.12.1.3,1.17.1.9,1.6.5.3	ko:K00123,ko:K00184,ko:K00335,ko:K00336,ko:K18006,ko:K18332	ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200	M00144	R00519,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1,5.A.3	-	-	Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,NADH-G_4Fe-4S_3
CMS1_k127_2996487_1	903818.KI912268_gene1462	3.832e-174	555.0	COG1894@1|root,COG1894@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	hoxF	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.12.1.2	ko:K18005	-	-	-	-	ko00000,ko01000	-	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
CMS1_k127_2996487_2	903818.KI912268_gene1461	9.921e-73	248.0	COG1905@1|root,COG1905@2|Bacteria	2|Bacteria	C	2 iron, 2 sulfur cluster binding	hoxF	-	1.12.1.2	ko:K18005	-	-	-	-	ko00000,ko01000	-	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
CMS1_k127_2996487_3	903818.KI912268_gene1460	3.443e-41	158.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	2.7.13.3	ko:K02282,ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035,ko02044	-	-	-	AAA_31,CheW,GGDEF,H-kinase_dim,HATPase_c,Hpt,Response_reg
CMS1_k127_3039229_0	1168034.FH5T_10945	5.359e-146	484.0	COG0855@1|root,COG0855@2|Bacteria,4NE3P@976|Bacteroidetes,2FM68@200643|Bacteroidia	976|Bacteroidetes	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
CMS1_k127_3039229_4	278963.ATWD01000001_gene2794	2.962e-50	188.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
CMS1_k127_3039229_1	395493.BegalDRAFT_3240	3.529e-123	411.0	COG2304@1|root,COG2304@2|Bacteria,1MUTS@1224|Proteobacteria,1RQPC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	von willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
CMS1_k127_3039229_2	1042375.AFPL01000006_gene2936	9.549e-99	342.0	COG0642@1|root,COG2205@2|Bacteria,1P4WV@1224|Proteobacteria,1T5IA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
CMS1_k127_3039229_3	207954.MED92_09151	4.012e-88	301.0	COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,1SYY4@1236|Gammaproteobacteria,1XHHH@135619|Oceanospirillales	135619|Oceanospirillales	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_304992_7	485917.Phep_3650	0.0009726	42.0	COG2133@1|root,COG2133@2|Bacteria,4PKJE@976|Bacteroidetes,1IP0E@117747|Sphingobacteriia	976|Bacteroidetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CMS1_k127_304992_2	1379270.AUXF01000002_gene1297	1.515e-106	356.0	COG0596@1|root,COG0596@2|Bacteria,1ZUZY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_304992_5	718252.FP2_18720	1.702e-67	239.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia,3WGMV@541000|Ruminococcaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
CMS1_k127_304992_6	1121396.KB893056_gene2647	4.73e-59	209.0	COG0503@1|root,COG0503@2|Bacteria,1MVZ6@1224|Proteobacteria,42QSH@68525|delta/epsilon subdivisions,2WP5X@28221|Deltaproteobacteria,2MJM5@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
CMS1_k127_304992_4	471854.Dfer_4313	1.578e-67	239.0	COG0546@1|root,COG2870@1|root,COG0546@2|Bacteria,COG2870@2|Bacteria,4NJ8F@976|Bacteroidetes,47MRA@768503|Cytophagia	976|Bacteroidetes	M	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase,PfkB
CMS1_k127_304992_3	886293.Sinac_2842	2.061e-69	243.0	COG2091@1|root,COG2091@2|Bacteria,2J06Q@203682|Planctomycetes	203682|Planctomycetes	H	Belongs to the P-Pant transferase superfamily	-	-	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
CMS1_k127_304992_0	497965.Cyan7822_1847	0.0	1609.0	COG0300@1|root,COG0318@1|root,COG1020@1|root,COG2267@1|root,COG3321@1|root,COG0300@2|Bacteria,COG0318@2|Bacteria,COG1020@2|Bacteria,COG2267@2|Bacteria,COG3321@2|Bacteria,1FZXE@1117|Cyanobacteria,3KG6F@43988|Cyanothece	1117|Cyanobacteria	Q	Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2,AMP-binding,Abhydrolase_1,Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,Sulfotransfer_3,ketoacyl-synt
CMS1_k127_304992_1	63737.Npun_R2083	1.824e-113	374.0	COG0236@1|root,COG0318@1|root,COG1960@1|root,COG0236@2|Bacteria,COG0318@2|Bacteria,COG1960@2|Bacteria,1G4CE@1117|Cyanobacteria,1HJ2S@1161|Nostocales	1117|Cyanobacteria	IQ	AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,PP-binding
CMS1_k127_3056181_0	158189.SpiBuddy_0853	1.109e-103	344.0	COG3842@1|root,COG3842@2|Bacteria,2J5T3@203691|Spirochaetes	203691|Spirochaetes	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
CMS1_k127_3056181_1	1144275.COCOR_02904	2.751e-88	310.0	COG0153@1|root,COG0153@2|Bacteria,1MVQD@1224|Proteobacteria,42Y39@68525|delta/epsilon subdivisions,2WSYZ@28221|Deltaproteobacteria,2YV2T@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the GHMP kinase family. GalK subfamily	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
CMS1_k127_3056181_6	1121403.AUCV01000042_gene138	0.0007598	50.0	COG4966@1|root,COG4966@2|Bacteria,1N2NR@1224|Proteobacteria,42TRJ@68525|delta/epsilon subdivisions,2WQQ2@28221|Deltaproteobacteria,2MKHU@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	pilus assembly protein PilW	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,PilW
CMS1_k127_3056181_4	1379698.RBG1_1C00001G1260	1.648e-64	242.0	2DRGI@1|root,33BMN@2|Bacteria	2|Bacteria	S	PilX N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PilX_N
CMS1_k127_3056181_2	76114.ebA4758	5.453e-86	287.0	COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,2VIJC@28216|Betaproteobacteria,2KUET@206389|Rhodocyclales	206389|Rhodocyclales	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
CMS1_k127_3056181_5	1173028.ANKO01000124_gene2827	7.934e-55	205.0	COG3021@1|root,COG3021@2|Bacteria,1G1V5@1117|Cyanobacteria,1HAVR@1150|Oscillatoriales	1117|Cyanobacteria	S	Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CMS1_k127_3056181_3	582744.Msip34_1554	1.291e-70	242.0	COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,2VHSH@28216|Betaproteobacteria,2KMDA@206350|Nitrosomonadales	206350|Nitrosomonadales	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
CMS1_k127_3068766_10	1232453.BAIF02000048_gene793	5.961e-79	292.0	COG3250@1|root,COG3250@2|Bacteria,1UZKP@1239|Firmicutes,24CWJ@186801|Clostridia	186801|Clostridia	G	alpha-L-rhamnosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106
CMS1_k127_3068766_16	926549.KI421517_gene359	4.007e-48	181.0	COG0170@1|root,COG0170@2|Bacteria,4P0IJ@976|Bacteroidetes,47TKF@768503|Cytophagia	976|Bacteroidetes	I	dolichyl monophosphate biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3068766_15	1131730.BAVI_15662	3.351e-48	190.0	COG0620@1|root,COG0620@2|Bacteria,1TP2H@1239|Firmicutes,4H9QC@91061|Bacilli,1ZBI7@1386|Bacillus	91061|Bacilli	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
CMS1_k127_3068766_11	1254432.SCE1572_36105	4.701e-73	254.0	COG1213@1|root,COG1213@2|Bacteria,1RB54@1224|Proteobacteria,42PKE@68525|delta/epsilon subdivisions,2X99A@28221|Deltaproteobacteria,2Z2QS@29|Myxococcales	28221|Deltaproteobacteria	M	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3
CMS1_k127_3068766_7	497964.CfE428DRAFT_2876	2.099e-85	286.0	COG2818@1|root,COG2818@2|Bacteria,46SS9@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Methyladenine glycosylase	-	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
CMS1_k127_3068766_5	945713.IALB_2925	2.889e-119	400.0	COG3004@1|root,COG3004@2|Bacteria	2|Bacteria	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
CMS1_k127_3068766_0	518766.Rmar_2224	3.594e-184	584.0	COG0372@1|root,COG0372@2|Bacteria,4NFXK@976|Bacteroidetes,1FIQ8@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
CMS1_k127_3068766_4	767817.Desgi_0684	1.545e-132	444.0	COG2871@1|root,COG3894@1|root,COG2871@2|Bacteria,COG3894@2|Bacteria,1TP0H@1239|Firmicutes,247S0@186801|Clostridia,261A2@186807|Peptococcaceae	186801|Clostridia	C	PFAM 2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
CMS1_k127_3068766_17	498761.HM1_2733	4.332e-39	153.0	COG0424@1|root,COG0424@2|Bacteria,1V6FH@1239|Firmicutes,24JRN@186801|Clostridia	186801|Clostridia	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
CMS1_k127_3068766_21	941449.dsx2_0103	2.786e-10	70.0	COG3599@1|root,COG3599@2|Bacteria,1NCAV@1224|Proteobacteria,42VH6@68525|delta/epsilon subdivisions,2WPC4@28221|Deltaproteobacteria,2MBBV@213115|Desulfovibrionales	28221|Deltaproteobacteria	D	PFAM DivIVA family protein	-	-	-	ko:K04074	-	-	-	-	ko00000,ko03036	-	-	-	DivIVA
CMS1_k127_3068766_14	1232410.KI421412_gene213	5.599e-52	193.0	COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,42P7F@68525|delta/epsilon subdivisions,2WJW9@28221|Deltaproteobacteria,43SDD@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Pyrroline-5-carboxylate reductase dimerisation	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0899	F420_oxidored,P5CR_dimer
CMS1_k127_3068766_19	795359.TOPB45_1526	6.465e-30	127.0	COG1246@1|root,COG1246@2|Bacteria,2GHN0@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	Acetyltransferase (GNAT) domain	-	-	2.3.1.1	ko:K00619	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
CMS1_k127_3068766_22	1235457.C404_02920	0.0005504	49.0	2E1T8@1|root,32X34@2|Bacteria,1N3BQ@1224|Proteobacteria,2VTYN@28216|Betaproteobacteria,1K6Z3@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3068766_20	1238182.C882_1918	2.269e-20	95.0	COG1553@1|root,COG1553@2|Bacteria,1RIKD@1224|Proteobacteria,2UBAT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Sulfur reduction protein DsrE	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
CMS1_k127_3068766_12	1146883.BLASA_3825	9.358e-61	218.0	COG1183@1|root,COG1183@2|Bacteria,2IC3M@201174|Actinobacteria	201174|Actinobacteria	I	phosphatidylcholine synthase	pcs	-	2.7.8.24	ko:K01004	ko00564,ko01110,map00564,map01110	-	R05794	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
CMS1_k127_3068766_18	279714.FuraDRAFT_2658	6.278e-39	147.0	COG3526@1|root,COG3526@2|Bacteria,1MZ5V@1224|Proteobacteria,2VUXZ@28216|Betaproteobacteria,2KT9Y@206351|Neisseriales	206351|Neisseriales	O	Rdx family	-	-	-	ko:K07401	-	-	-	-	ko00000	-	-	-	Rdx
CMS1_k127_3068766_13	886293.Sinac_3768	2.683e-54	213.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,DUF4241
CMS1_k127_3068766_3	929703.KE386491_gene3837	6.923e-135	445.0	COG0531@1|root,COG0531@2|Bacteria,4NJPZ@976|Bacteroidetes,47MX2@768503|Cytophagia	976|Bacteroidetes	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
CMS1_k127_3068766_6	1267535.KB906767_gene193	6.883e-101	338.0	COG3386@1|root,COG3386@2|Bacteria,3Y6WN@57723|Acidobacteria	57723|Acidobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3068766_8	335543.Sfum_2656	7.473e-84	284.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42MP1@68525|delta/epsilon subdivisions,2WJPD@28221|Deltaproteobacteria,2MRKV@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	PFAM response regulator receiver	-	-	-	ko:K07663,ko:K07664	ko02020,map02020	M00449,M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_3068766_2	316067.Geob_3646	3.489e-135	449.0	COG0642@1|root,COG2205@2|Bacteria,1N17V@1224|Proteobacteria,42PMH@68525|delta/epsilon subdivisions,2WKZU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07641,ko:K14980	ko02020,map02020	M00449,M00520	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,dCache_3
CMS1_k127_3068766_9	1396418.BATQ01000007_gene1447	6.205e-83	290.0	2DR4U@1|root,33A62@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CreD
CMS1_k127_3068766_1	485917.Phep_0351	1.781e-181	582.0	COG4257@1|root,COG4257@2|Bacteria,4P0GZ@976|Bacteroidetes,1IW5R@117747|Sphingobacteriia	976|Bacteroidetes	V	antibiotic catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3071335_13	1216007.AOPM01000105_gene20	6.137e-33	132.0	COG3431@1|root,COG3431@2|Bacteria,1N6PE@1224|Proteobacteria,1S9EB@1236|Gammaproteobacteria,2Q310@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	Sensors of blue-light using FAD	-	-	-	-	-	-	-	-	-	-	-	-	BLUF
CMS1_k127_3071335_11	1123401.JHYQ01000046_gene2211	2.38e-56	206.0	COG3040@1|root,COG3040@2|Bacteria,1RDAI@1224|Proteobacteria,1S3PW@1236|Gammaproteobacteria,460TT@72273|Thiotrichales	72273|Thiotrichales	M	Lipocalin-like domain	-	-	-	ko:K03098	-	-	-	-	ko00000,ko04147	-	-	-	Lipocalin_2
CMS1_k127_3071335_12	194439.CT2083	3.786e-47	177.0	COG0702@1|root,COG0702@2|Bacteria,1FE8P@1090|Chlorobi	1090|Chlorobi	C	PFAM NADH ubiquinone oxidoreductase complex I intermediate-associated protein 30	-	-	-	-	-	-	-	-	-	-	-	-	CIA30
CMS1_k127_3071335_8	1328313.DS2_08565	2.091e-79	273.0	COG2834@1|root,COG2834@2|Bacteria,1MXW0@1224|Proteobacteria,1RS0K@1236|Gammaproteobacteria,4664W@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Outer membrane lipoprotein-sorting protein	VP1287	-	-	-	-	-	-	-	-	-	-	-	LolA_like
CMS1_k127_3071335_2	203122.Sde_1321	1.068e-207	671.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RPIP@1236|Gammaproteobacteria,465BT@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	exporters of the RND superfamily	VP1286	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
CMS1_k127_3071335_4	1049564.TevJSym_al00220	7.311e-128	421.0	28I6N@1|root,2Z89J@2|Bacteria,1MUVT@1224|Proteobacteria,1RQUY@1236|Gammaproteobacteria,1J7IW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3071335_1	118161.KB235922_gene570	3.707e-249	817.0	COG3321@1|root,COG3321@2|Bacteria,1FZXE@1117|Cyanobacteria	1117|Cyanobacteria	Q	Beta-ketoacyl synthase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N_2,Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,Sulfotransfer_3,Thioesterase,ketoacyl-synt
CMS1_k127_3071335_3	1206735.BAGG01000050_gene2077	5.241e-135	445.0	COG0635@1|root,COG0635@2|Bacteria,2I16T@201174|Actinobacteria	201174|Actinobacteria	H	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
CMS1_k127_3071335_0	211165.AJLN01000051_gene5004	0.0	1054.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria	1117|Cyanobacteria	Q	Amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
CMS1_k127_3071335_6	1242864.D187_005409	5.102e-94	324.0	COG2124@1|root,COG2124@2|Bacteria,1MV75@1224|Proteobacteria,42NH2@68525|delta/epsilon subdivisions,2X33V@28221|Deltaproteobacteria,2YU3J@29|Myxococcales	28221|Deltaproteobacteria	C	cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
CMS1_k127_3071335_7	1242864.D187_005409	8.837e-86	301.0	COG2124@1|root,COG2124@2|Bacteria,1MV75@1224|Proteobacteria,42NH2@68525|delta/epsilon subdivisions,2X33V@28221|Deltaproteobacteria,2YU3J@29|Myxococcales	28221|Deltaproteobacteria	C	cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
CMS1_k127_3071335_9	307480.IW16_03515	1.417e-66	236.0	COG1028@1|root,COG1028@2|Bacteria,4NEAI@976|Bacteroidetes,1HXDZ@117743|Flavobacteriia,3ZPBB@59732|Chryseobacterium	976|Bacteroidetes	IQ	3-ketoacyl-ACP reductase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS1_k127_3071335_14	977880.pRALTA_0086	7.066e-05	46.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,2VNU5@28216|Betaproteobacteria,1K1AA@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
CMS1_k127_3071335_16	216591.BCAL0087	0.0008789	47.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,2VNU5@28216|Betaproteobacteria,1K1AA@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
CMS1_k127_3071335_15	160488.PP_4445	0.0004362	43.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,1RR4F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG2801 Transposase and inactivated derivatives	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
CMS1_k127_3071335_5	329726.AM1_1239	7.245e-125	421.0	COG2931@1|root,COG3391@1|root,COG2931@2|Bacteria,COG3391@2|Bacteria,1G0EB@1117|Cyanobacteria	1117|Cyanobacteria	DZ	PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Calx-beta,DUF4347,He_PIG,HemolysinCabind,PPC,TIG,VCBS
CMS1_k127_3073583_7	1121355.KB903379_gene745	1.669e-06	53.0	COG0544@1|root,COG0544@2|Bacteria,2GJIG@201174|Actinobacteria,22JV9@1653|Corynebacteriaceae	201174|Actinobacteria	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
CMS1_k127_3073583_2	1122919.KB905565_gene2639	2.383e-81	284.0	COG0673@1|root,COG0673@2|Bacteria,1TQ72@1239|Firmicutes,4HCS4@91061|Bacilli,26RZ0@186822|Paenibacillaceae	91061|Bacilli	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_3073583_1	977880.RALTA_A2893	1.466e-96	331.0	COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,2VHXR@28216|Betaproteobacteria,1K17C@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
CMS1_k127_3073583_8	189753.AXAS01000004_gene956	5.767e-06	57.0	COG0457@1|root,COG0457@2|Bacteria,1NG0U@1224|Proteobacteria,2U0YA@28211|Alphaproteobacteria,3K0QN@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_2,TPR_8
CMS1_k127_3073583_4	452637.Oter_4555	2.356e-20	98.0	2C0ZJ@1|root,33VV4@2|Bacteria,46VGY@74201|Verrucomicrobia,3K7JZ@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3073583_3	1144275.COCOR_06436	1.406e-77	263.0	COG4894@1|root,COG4894@2|Bacteria,1RKPJ@1224|Proteobacteria,434XW@68525|delta/epsilon subdivisions,2WZ8Q@28221|Deltaproteobacteria,2Z1KE@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3073583_0	1123242.JH636435_gene1524	5.976e-109	378.0	COG2936@1|root,COG2936@2|Bacteria,2J2G5@203682|Planctomycetes	203682|Planctomycetes	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
CMS1_k127_3073583_5	888743.HMPREF9141_1170	6.809e-12	69.0	COG1397@1|root,COG5579@1|root,COG1397@2|Bacteria,COG5579@2|Bacteria,4NTDS@976|Bacteroidetes,2G0U6@200643|Bacteroidia	976|Bacteroidetes	O	Protein of unknown function (DUF1810)	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH,DUF1810
CMS1_k127_3077673_0	661478.OP10G_2040	4.616e-166	547.0	COG1874@1|root,COG1874@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	3.2.1.23,3.2.1.81	ko:K01190,ko:K01219,ko:K12308	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Cellulase,Glyco_hydro_42,Glyco_hydro_42M
CMS1_k127_3077673_4	1111479.AXAR01000001_gene311	6.599e-73	252.0	COG5482@1|root,COG5482@2|Bacteria,1V3FI@1239|Firmicutes,4HI6C@91061|Bacilli	91061|Bacilli	S	Putative PD-(D/E)XK phosphodiesterase (DUF2161)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2161
CMS1_k127_3077673_8	1336803.PHEL49_2055	1.874e-16	89.0	2F15V@1|root,33U6Z@2|Bacteria,4P2EZ@976|Bacteroidetes,1I8VB@117743|Flavobacteriia,3VX0P@52959|Polaribacter	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3077673_5	1122919.KB905551_gene1682	3.119e-56	213.0	COG3828@1|root,COG3828@2|Bacteria	2|Bacteria	N	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
CMS1_k127_3077673_2	1122604.JONR01000001_gene2026	1.548e-115	383.0	COG0451@1|root,COG0451@2|Bacteria,1P603@1224|Proteobacteria,1RQ2R@1236|Gammaproteobacteria,1X41X@135614|Xanthomonadales	135614|Xanthomonadales	M	3-beta hydroxysteroid dehydrogenase	cdh1	-	1.1.1.412	ko:K22320	-	-	-	-	ko00000,ko01000	-	-	-	3Beta_HSD
CMS1_k127_3077673_10	521000.PROVRETT_08841	0.0002777	55.0	COG5373@1|root,COG5373@2|Bacteria,1N08V@1224|Proteobacteria,1RNGS@1236|Gammaproteobacteria,3Z8AB@586|Providencia	1236|Gammaproteobacteria	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
CMS1_k127_3077673_9	688269.Theth_0183	4.251e-07	58.0	COG1366@1|root,COG1366@2|Bacteria,2GDAN@200918|Thermotogae	200918|Thermotogae	T	PFAM Sulfate transporter antisigma-factor antagonist STAS	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
CMS1_k127_3077673_3	697281.Mahau_1101	1.306e-107	353.0	COG4813@1|root,COG4813@2|Bacteria,1TPZ1@1239|Firmicutes,24EF0@186801|Clostridia,42HMI@68295|Thermoanaerobacterales	186801|Clostridia	G	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
CMS1_k127_3077673_1	1121011.AUCB01000006_gene1017	1.368e-150	493.0	COG0591@1|root,COG0591@2|Bacteria,4PKHI@976|Bacteroidetes,1I0X7@117743|Flavobacteriia,23FWQ@178469|Arenibacter	976|Bacteroidetes	E	Sodium:solute symporter family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
CMS1_k127_3084136_1	290397.Adeh_1534	6.992e-44	162.0	COG1146@1|root,COG1146@2|Bacteria,1RH5I@1224|Proteobacteria,43C2Q@68525|delta/epsilon subdivisions,2WSJ0@28221|Deltaproteobacteria,2YVH1@29|Myxococcales	28221|Deltaproteobacteria	C	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions	-	-	-	ko:K05524	-	-	-	-	ko00000	-	-	-	DUF3470,Fer4
CMS1_k127_3084136_0	671143.DAMO_2498	9.517e-127	411.0	COG1180@1|root,COG1180@2|Bacteria,2NP82@2323|unclassified Bacteria	2|Bacteria	O	Radical SAM superfamily	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
CMS1_k127_309493_1	497964.CfE428DRAFT_4954	5.546e-16	86.0	COG1621@1|root,COG1621@2|Bacteria,46VBA@74201|Verrucomicrobia	74201|Verrucomicrobia	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3095329_2	1220589.CD32_20305	1.544e-72	260.0	COG1914@1|root,COG1914@2|Bacteria,1U5FJ@1239|Firmicutes,4IDYK@91061|Bacilli,3IZYG@400634|Lysinibacillus	91061|Bacilli	P	Natural resistance-associated macrophage protein	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
CMS1_k127_3095329_1	765913.ThidrDRAFT_0206	8.519e-120	391.0	COG0583@1|root,COG0583@2|Bacteria,1MU8N@1224|Proteobacteria,1RXZ5@1236|Gammaproteobacteria,1WXP8@135613|Chromatiales	135613|Chromatiales	K	Transcriptional regulator, LysR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS1_k127_3095329_0	870187.Thini_0399	1.496e-190	602.0	COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,1RMNR@1236|Gammaproteobacteria,4609K@72273|Thiotrichales	72273|Thiotrichales	E	Aminotransferase class-V	-	-	2.6.1.44,2.6.1.45,2.6.1.51	ko:K00830	ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	M00346,M00532	R00369,R00372,R00585,R00588	RC00006,RC00008,RC00018	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
CMS1_k127_3098065_4	1120956.JHZK01000032_gene122	9.962e-74	259.0	COG0475@1|root,COG0475@2|Bacteria,1R5QJ@1224|Proteobacteria	1224|Proteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
CMS1_k127_3098065_0	472759.Nhal_1374	3.14e-211	674.0	COG4805@1|root,COG4805@2|Bacteria,1R5EP@1224|Proteobacteria,1RRS6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
CMS1_k127_3098065_9	1232437.KL662016_gene1217	3.206e-16	80.0	COG3440@1|root,COG3440@2|Bacteria,1NE0N@1224|Proteobacteria,43EWK@68525|delta/epsilon subdivisions,2WM8A@28221|Deltaproteobacteria,2MP6G@213118|Desulfobacterales	28221|Deltaproteobacteria	V	HNH endonuclease	-	-	-	ko:K07454	-	-	-	-	ko00000	-	-	-	HNH_2
CMS1_k127_3098065_5	1340493.JNIF01000004_gene359	1.651e-59	223.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	Z012_03425	-	3.1.6.14	ko:K01137,ko:K01138	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00078,M00079	R07808,R07819	-	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4976,Sulfatase
CMS1_k127_3098065_1	497964.CfE428DRAFT_5300	1.248e-169	546.0	COG0673@1|root,COG0673@2|Bacteria,46S8U@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_3098065_2	1210884.HG799464_gene10355	1.027e-92	318.0	COG0582@1|root,COG0582@2|Bacteria,2IYXX@203682|Planctomycetes	203682|Planctomycetes	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
CMS1_k127_3098065_3	760192.Halhy_1763	5.719e-91	314.0	COG0457@1|root,COG2319@1|root,COG0457@2|Bacteria,COG2319@2|Bacteria,4NH20@976|Bacteroidetes,1IQXJ@117747|Sphingobacteriia	976|Bacteroidetes	B	PFAM WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	WD40
CMS1_k127_3098065_8	156889.Mmc1_2627	9.324e-19	87.0	COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria,2U24Y@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Integrase	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	rve_3
CMS1_k127_3098065_7	497964.CfE428DRAFT_4476	4.888e-19	101.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	I-set,Ig_3,PQQ_2
CMS1_k127_3098065_6	1123276.KB893250_gene317	5.535e-26	123.0	COG2755@1|root,COG3391@1|root,COG2755@2|Bacteria,COG3391@2|Bacteria,4PI0M@976|Bacteroidetes,47R8B@768503|Cytophagia	976|Bacteroidetes	E	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
CMS1_k127_3106131_0	1056820.KB900630_gene1537	4.829e-149	486.0	COG4166@1|root,COG4166@2|Bacteria,1P91R@1224|Proteobacteria,1RN57@1236|Gammaproteobacteria,2PP7B@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	oppA	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
CMS1_k127_3108774_0	378806.STAUR_2130	1.34e-93	341.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,1MWJA@1224|Proteobacteria,42P8D@68525|delta/epsilon subdivisions,2WMH1@28221|Deltaproteobacteria,2YY1Q@29|Myxococcales	28221|Deltaproteobacteria	KLT	Phosphotransferase enzyme family	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,Pkinase_Tyr,WD40
CMS1_k127_3108774_1	497964.CfE428DRAFT_0545	2.576e-57	208.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_3108860_11	167539.Pro_0859	6.02e-09	57.0	COG0777@1|root,COG0777@2|Bacteria,1G1ZY@1117|Cyanobacteria,1MKJD@1212|Prochloraceae	1117|Cyanobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.accD	Carboxyl_trans
CMS1_k127_3108860_4	378806.STAUR_3457	2.576e-78	279.0	COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,42N08@68525|delta/epsilon subdivisions,2WIW9@28221|Deltaproteobacteria,2YUTG@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2475	Mur_ligase_C,Mur_ligase_M
CMS1_k127_3108860_1	452637.Oter_3478	2.595e-190	600.0	COG0059@1|root,COG0059@2|Bacteria,46SI2@74201|Verrucomicrobia,3K7PK@414999|Opitutae	74201|Verrucomicrobia	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
CMS1_k127_3108860_0	373903.Hore_15760	1.034e-205	661.0	COG3808@1|root,COG3808@2|Bacteria,1TNZI@1239|Firmicutes,248KS@186801|Clostridia,3WA8T@53433|Halanaerobiales	186801|Clostridia	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
CMS1_k127_3108860_5	585503.HMPREF7545_1130	3.954e-50	186.0	COG0571@1|root,COG0571@2|Bacteria,1TPGC@1239|Firmicutes,4H2IB@909932|Negativicutes	909932|Negativicutes	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
CMS1_k127_3108860_2	1444309.JAQG01000008_gene1702	5.051e-139	456.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli,26QJA@186822|Paenibacillaceae	91061|Bacilli	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF3	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
CMS1_k127_3108860_9	909663.KI867150_gene825	1.621e-18	87.0	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,42V9M@68525|delta/epsilon subdivisions,2WRDW@28221|Deltaproteobacteria,2MQPR@213462|Syntrophobacterales	28221|Deltaproteobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
CMS1_k127_3108860_10	519442.Huta_2907	2.488e-11	73.0	COG0727@1|root,arCOG02579@2157|Archaea,2XTK2@28890|Euryarchaeota,23RYP@183963|Halobacteria	183963|Halobacteria	S	Fe-S-cluster oxidoreductase	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
CMS1_k127_3108860_6	1089548.KI783301_gene3147	3.14e-41	166.0	COG0739@1|root,COG0739@2|Bacteria,1V3ZU@1239|Firmicutes,4HGM6@91061|Bacilli	91061|Bacilli	M	Membrane proteins related to metalloendopeptidases	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
CMS1_k127_3108860_8	1499967.BAYZ01000158_gene436	1.125e-18	91.0	COG1664@1|root,COG1664@2|Bacteria,2NQ1N@2323|unclassified Bacteria	2|Bacteria	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
CMS1_k127_3108860_3	1121472.AQWN01000005_gene2506	1.635e-103	347.0	COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,247YV@186801|Clostridia,2608Q@186807|Peptococcaceae	186801|Clostridia	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
CMS1_k127_3108860_7	1382359.JIAL01000001_gene1944	6.028e-25	114.0	COG3250@1|root,COG3250@2|Bacteria,3Y6RC@57723|Acidobacteria,2JKAB@204432|Acidobacteriia	204432|Acidobacteriia	G	alpha-L-rhamnosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106
CMS1_k127_3113825_5	1366050.N234_10795	2.65e-20	95.0	COG0421@1|root,COG0421@2|Bacteria,1P220@1224|Proteobacteria,2VNDM@28216|Betaproteobacteria,1KBX2@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Spermine/spermidine synthase domain	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
CMS1_k127_3113825_1	1173026.Glo7428_2548	5.223e-195	642.0	COG2202@1|root,COG5001@1|root,COG5002@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,COG5002@2|Bacteria,1G0SY@1117|Cyanobacteria	1117|Cyanobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,PAS_3,PAS_9
CMS1_k127_3113825_2	448385.sce5487	2.607e-73	268.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,1MV1P@1224|Proteobacteria,430N6@68525|delta/epsilon subdivisions,2WVRE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Pkinase
CMS1_k127_3113825_4	1123508.JH636447_gene7942	2.419e-56	208.0	COG0800@1|root,COG0800@2|Bacteria,2IXBP@203682|Planctomycetes	203682|Planctomycetes	G	PFAM KDPG and KHG aldolase	-	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
CMS1_k127_3113825_3	344747.PM8797T_13438	5.59e-66	244.0	COG1506@1|root,COG1506@2|Bacteria,2J2Q6@203682|Planctomycetes	203682|Planctomycetes	E	Esterase PHB depolymerase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
CMS1_k127_3113825_0	521674.Plim_1366	1.643e-292	915.0	COG0243@1|root,COG0243@2|Bacteria,2IXVV@203682|Planctomycetes	203682|Planctomycetes	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdopterin,Molydop_binding
CMS1_k127_3113825_6	240015.ACP_2495	9.543e-18	84.0	COG1158@1|root,COG1158@2|Bacteria,3Y2V3@57723|Acidobacteria,2JHRC@204432|Acidobacteriia	204432|Acidobacteriia	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
CMS1_k127_3120113_4	335543.Sfum_1614	8.884e-29	120.0	COG3825@1|root,COG3825@2|Bacteria,1MUAJ@1224|Proteobacteria,42N7R@68525|delta/epsilon subdivisions,2WJBI@28221|Deltaproteobacteria,2MR3A@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	VWA containing CoxE family protein	-	-	-	ko:K09989	-	-	-	-	ko00000	-	-	-	VWA_CoxE
CMS1_k127_3120113_5	1321778.HMPREF1982_02132	1.215e-06	53.0	2AFI1@1|root,315IM@2|Bacteria,1UUJJ@1239|Firmicutes,256YF@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3120113_3	1123368.AUIS01000032_gene1401	5.128e-35	139.0	2D5Q1@1|root,32TJK@2|Bacteria,1N688@1224|Proteobacteria,1SS8Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3120113_1	335543.Sfum_1615	2.434e-98	332.0	COG0714@1|root,COG0714@2|Bacteria,1MV5I@1224|Proteobacteria,42MTW@68525|delta/epsilon subdivisions,2WJ0J@28221|Deltaproteobacteria,2MRC6@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	AAA domain (Cdc48 subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
CMS1_k127_3120113_2	234267.Acid_1540	6.764e-50	190.0	COG4798@1|root,COG4798@2|Bacteria,3Y5JR@57723|Acidobacteria	57723|Acidobacteria	S	Met-10+ like-protein	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
CMS1_k127_3120113_0	382464.ABSI01000011_gene2820	3.807e-304	961.0	COG0612@1|root,COG0612@2|Bacteria,46VKF@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
CMS1_k127_3123292_3	1267535.KB906767_gene2950	4.928e-107	364.0	COG2319@1|root,COG2319@2|Bacteria,3Y69Q@57723|Acidobacteria	57723|Acidobacteria	S	Wd-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3123292_9	644801.Psest_0250	2.933e-05	56.0	COG1215@1|root,COG1215@2|Bacteria,1P7GR@1224|Proteobacteria,1RNP2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Bacteriophage N4 adsorption protein B	nfrB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K11740	-	-	-	-	ko00000	-	-	-	Glyco_trans_2_3,T2SSE_N
CMS1_k127_3123292_8	8081.XP_008394857.1	1.99e-07	65.0	KOG1947@1|root,KOG1947@2759|Eukaryota,39R58@33154|Opisthokonta,3BB4U@33208|Metazoa,3D43V@33213|Bilateria,48C0H@7711|Chordata,495N5@7742|Vertebrata,49SRA@7898|Actinopterygii	33208|Metazoa	A	Leucine-rich repeats, outliers	-	-	-	-	-	-	-	-	-	-	-	-	LRR_6,UBX
CMS1_k127_3123292_6	429009.Adeg_1725	1.377e-14	87.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,247KA@186801|Clostridia,42FCP@68295|Thermoanaerobacterales	186801|Clostridia	NU	PFAM Type II secretion system protein E	pilB	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
CMS1_k127_3123292_7	1121439.dsat_1839	8.595e-12	78.0	COG1639@1|root,COG1639@2|Bacteria,1RAH3@1224|Proteobacteria,42PRF@68525|delta/epsilon subdivisions,2WMIN@28221|Deltaproteobacteria,2M912@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM Metal-dependent hydrolase HDOD	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
CMS1_k127_3123292_5	580332.Slit_2374	1.597e-21	98.0	COG2346@1|root,COG2346@2|Bacteria	2|Bacteria	O	COG2346, Truncated hemoglobins	glbN	GO:0001505,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008941,GO:0009056,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0016491,GO:0016705,GO:0016708,GO:0017144,GO:0019825,GO:0020012,GO:0020037,GO:0030682,GO:0034641,GO:0036094,GO:0042133,GO:0042135,GO:0042221,GO:0042737,GO:0043207,GO:0044237,GO:0044248,GO:0044270,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046209,GO:0046210,GO:0046906,GO:0048037,GO:0050896,GO:0051213,GO:0051410,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0065007,GO:0065008,GO:0072593,GO:0075136,GO:0097159,GO:0098754,GO:1901363,GO:1901698,GO:2001057	-	ko:K03406,ko:K06886	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	Bac_globin
CMS1_k127_3123292_0	1121413.JMKT01000008_gene1381	2.307e-134	451.0	COG0729@1|root,COG0729@2|Bacteria,1MUKM@1224|Proteobacteria,42MB2@68525|delta/epsilon subdivisions,2WJAF@28221|Deltaproteobacteria,2M7RN@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM surface antigen (D15)	-	-	-	ko:K07277,ko:K07278	-	-	-	-	ko00000,ko02000,ko03029	1.B.33,1.B.33.2.4	-	-	Bac_surface_Ag,POTRA,POTRA_TamA_1
CMS1_k127_3123292_2	1089551.KE386572_gene1456	2.741e-118	428.0	COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,2TR45@28211|Alphaproteobacteria,4BQ67@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	TamB, inner membrane protein subunit of TAM complex	tamB	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
CMS1_k127_3123292_4	886293.Sinac_3363	2.321e-45	177.0	COG4299@1|root,COG4299@2|Bacteria,2IYKU@203682|Planctomycetes	203682|Planctomycetes	S	COGs COG4299 conserved	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
CMS1_k127_3123292_1	616991.JPOO01000003_gene2393	1.045e-127	420.0	COG3292@1|root,COG3292@2|Bacteria,4P1XS@976|Bacteroidetes	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3133592_0	639030.JHVA01000001_gene604	2.698e-106	353.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.4.21.96	ko:K01361,ko:K13277,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Amidase_2,Big_2,CBM_X2,DUF1983,DUF2961,Glucosaminidase,LRR_5,Laminin_G_3,PA,Peptidase_S8,Phage-tail_3,SLH,fn3_5
CMS1_k127_3133592_1	177437.HRM2_40530	7.014e-74	260.0	2CFUQ@1|root,2ZC1I@2|Bacteria,1RBHI@1224|Proteobacteria,42QR4@68525|delta/epsilon subdivisions,2WMXI@28221|Deltaproteobacteria,2MJQJ@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3145420_3	1521187.JPIM01000055_gene3654	1.341e-16	90.0	COG2334@1|root,COG2334@2|Bacteria,2G9QM@200795|Chloroflexi,3762I@32061|Chloroflexia	32061|Chloroflexia	S	PFAM aminoglycoside phosphotransferase	-	-	2.7.1.39	ko:K02204	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	APH
CMS1_k127_3145420_1	1499968.TCA2_3913	2.081e-65	236.0	COG1175@1|root,COG1175@2|Bacteria,1TT6K@1239|Firmicutes,4HBZJ@91061|Bacilli,26S0J@186822|Paenibacillaceae	91061|Bacilli	G	spermidine putrescine ABC transporter, permease	-	-	-	ko:K02025,ko:K17238	ko02010,map02010	M00207,M00599	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.38	-	-	BPD_transp_1
CMS1_k127_3145420_2	1128421.JAGA01000001_gene2310	2.46e-61	221.0	COG0395@1|root,COG0395@2|Bacteria,2NQVR@2323|unclassified Bacteria	2|Bacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026,ko:K17236	ko02010,map02010	M00207,M00602	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.34	-	-	BPD_transp_1
CMS1_k127_3145420_4	1408303.JNJJ01000086_gene2936	2.585e-14	86.0	COG1653@1|root,COG1653@2|Bacteria,1TQE5@1239|Firmicutes,4ISFU@91061|Bacilli,1ZESW@1386|Bacillus	91061|Bacilli	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1
CMS1_k127_3145420_0	351160.RCIX1702	3.426e-66	237.0	COG1266@1|root,arCOG02768@2157|Archaea,2Y1H1@28890|Euryarchaeota	28890|Euryarchaeota	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
CMS1_k127_3145420_5	1123277.KB893228_gene2107	1.425e-05	47.0	COG3119@1|root,COG3119@2|Bacteria,4NHFD@976|Bacteroidetes,47TGB@768503|Cytophagia	976|Bacteroidetes	P	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CMS1_k127_3151020_9	497964.CfE428DRAFT_5098	3.892e-31	143.0	COG1075@1|root,COG1404@1|root,COG3055@1|root,COG3391@1|root,COG1075@2|Bacteria,COG1404@2|Bacteria,COG3055@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	1.1.3.6,3.2.1.4	ko:K01179,ko:K03333,ko:K12287	ko00500,ko00984,ko01100,ko01120,map00500,map00984,map01100,map01120	-	R01459,R06200,R11307,R11308	RC00146	ko00000,ko00001,ko01000,ko02044	-	GH5,GH9	-	Kelch_1,Laminin_G_3,Malectin
CMS1_k127_3151020_3	177437.HRM2_05730	2.831e-71	273.0	COG4412@1|root,COG4412@2|Bacteria,1MWWV@1224|Proteobacteria,42S3D@68525|delta/epsilon subdivisions,2WNYK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Large extracellular alpha-helical protein	-	-	-	ko:K09607	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C13
CMS1_k127_3151020_13	1123501.KB902288_gene1780	2.865e-15	86.0	29681@1|root,2ZTI1@2|Bacteria,1RA8W@1224|Proteobacteria,2U6CU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Peptidase M50B-like	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50B
CMS1_k127_3151020_7	572479.Hprae_2075	2.415e-40	163.0	2DFXS@1|root,2ZTMH@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2330,Kunitz_BPTI
CMS1_k127_3151020_14	1123269.NX02_14280	1.001e-07	65.0	COG5434@1|root,COG5434@2|Bacteria,1QH2X@1224|Proteobacteria,2U1H2@28211|Alphaproteobacteria,2K23J@204457|Sphingomonadales	204457|Sphingomonadales	M	Glycosyl hydrolases family 28	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Pectate_lyase_3
CMS1_k127_3151020_12	247490.KSU1_C1333	5.194e-17	92.0	COG4968@1|root,COG4968@2|Bacteria,2J519@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CMS1_k127_3151020_6	644966.Tmar_1404	7.37e-49	187.0	COG0584@1|root,COG0671@1|root,COG0584@2|Bacteria,COG0671@2|Bacteria,1V3W4@1239|Firmicutes,24AVJ@186801|Clostridia,3WD9W@538999|Clostridiales incertae sedis	186801|Clostridia	C	PFAM Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD,PAP2
CMS1_k127_3151020_4	56780.SYN_00659	2.927e-60	228.0	COG0834@1|root,COG1073@1|root,COG0834@2|Bacteria,COG1073@2|Bacteria,1N3ZN@1224|Proteobacteria,42VWV@68525|delta/epsilon subdivisions	1224|Proteobacteria	ET	Cache domain	-	-	-	-	-	-	-	-	-	-	-	-	dCache_1
CMS1_k127_3151020_5	794903.OPIT5_13310	2.053e-54	208.0	COG3858@1|root,COG3858@2|Bacteria,46VGZ@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF3142)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3142
CMS1_k127_3151020_2	794903.OPIT5_13315	3.338e-87	317.0	COG3063@1|root,COG3063@2|Bacteria,46UEF@74201|Verrucomicrobia	74201|Verrucomicrobia	NU	Type IV pilus biogenesis stability protein PilW	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3151020_8	886293.Sinac_4562	1.413e-36	155.0	COG1904@1|root,COG1904@2|Bacteria,2J28E@203682|Planctomycetes	203682|Planctomycetes	G	glucuronate isomerase	-	-	5.3.1.12	ko:K01812	ko00040,ko01100,map00040,map01100	M00061,M00631	R01482,R01983	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	-
CMS1_k127_3151020_0	517418.Ctha_2453	0.0	1229.0	COG1048@1|root,COG1048@2|Bacteria,1FF0B@1090|Chlorobi	1090|Chlorobi	C	Aconitase C-terminal domain	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
CMS1_k127_3151020_10	1280686.AUKE01000015_gene502	2.851e-28	123.0	COG2199@1|root,COG2199@2|Bacteria,1UJA2@1239|Firmicutes,25EZ1@186801|Clostridia,4BYM3@830|Butyrivibrio	186801|Clostridia	T	Ribbon-helix-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,RHH_3
CMS1_k127_3151020_1	1120973.AQXL01000133_gene1795	1.856e-142	458.0	COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,4HAWA@91061|Bacilli,278ZJ@186823|Alicyclobacillaceae	91061|Bacilli	E	Aconitase family (aconitate hydratase)	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS10700	Aconitase
CMS1_k127_3153910_1	28258.KP05_02505	2.461e-08	63.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1XHRM@135619|Oceanospirillales	135619|Oceanospirillales	M	Belongs to the peptidase S1C family	mucD	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
CMS1_k127_3153910_0	1125863.JAFN01000001_gene2915	8.308e-175	557.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,42MBF@68525|delta/epsilon subdivisions,2WJQ2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	PFAM Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CMS1_k127_3154366_0	314265.R2601_10304	3.066e-84	291.0	COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,1PBHA@1224|Proteobacteria,2TRQF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG2801 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve,rve_3
CMS1_k127_3154366_1	1123360.thalar_02507	4.511e-32	129.0	COG2963@1|root,COG2963@2|Bacteria,1RHKX@1224|Proteobacteria,2U9TV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG2963 Transposase and inactivated derivatives	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
CMS1_k127_3155874_1	1464048.JNZS01000009_gene5888	2.871e-05	54.0	COG0346@1|root,COG0346@2|Bacteria,2GS59@201174|Actinobacteria,4DGI8@85008|Micromonosporales	201174|Actinobacteria	E	Glyoxalase bleomycin resistance protein dioxygenase	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase,Glyoxalase_2
CMS1_k127_3155874_0	483219.LILAB_19265	1.295e-125	411.0	COG0604@1|root,COG0604@2|Bacteria,1MXUX@1224|Proteobacteria,43C6E@68525|delta/epsilon subdivisions,2WTIV@28221|Deltaproteobacteria,2YZ25@29|Myxococcales	28221|Deltaproteobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_3168300_0	661478.OP10G_2798	1.625e-90	316.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
CMS1_k127_3168300_2	1121459.AQXE01000004_gene1665	2.799e-15	84.0	COG1807@1|root,COG1807@2|Bacteria,1P6JE@1224|Proteobacteria,42QEZ@68525|delta/epsilon subdivisions,2WKYB@28221|Deltaproteobacteria,2M7X0@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS1_k127_3169311_5	1382356.JQMP01000003_gene1430	1.95e-25	115.0	COG2197@1|root,COG2197@2|Bacteria,2G6PA@200795|Chloroflexi,27YVM@189775|Thermomicrobia	189775|Thermomicrobia	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS1_k127_3169311_4	401526.TcarDRAFT_0238	4.31e-51	190.0	COG2197@1|root,COG2197@2|Bacteria,1TSBV@1239|Firmicutes,4H2KJ@909932|Negativicutes	909932|Negativicutes	T	PFAM response regulator receiver, regulatory protein LuxR	-	-	-	ko:K07696	ko02020,map02020	M00483	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
CMS1_k127_3169311_2	926550.CLDAP_03360	1.347e-64	240.0	COG4585@1|root,COG5000@1|root,COG4585@2|Bacteria,COG5000@2|Bacteria,2G6F0@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA_3,sCache_3_2
CMS1_k127_3169311_3	1123355.JHYO01000017_gene3613	4.648e-57	219.0	COG2010@1|root,COG2010@2|Bacteria,1REKI@1224|Proteobacteria,2UA53@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CMS1_k127_3169311_1	1380387.JADM01000003_gene2595	4.268e-129	434.0	COG1409@1|root,COG1409@2|Bacteria,1NS3S@1224|Proteobacteria,1RR8K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
CMS1_k127_3169311_0	700598.Niako_3627	4.002e-134	438.0	COG0697@1|root,2Z7ID@2|Bacteria,4NEHB@976|Bacteroidetes,1IVNN@117747|Sphingobacteriia	976|Bacteroidetes	EG	L-rhamnose-proton symport protein (RhaT)	rhaT	-	-	ko:K02856	-	-	-	-	ko00000,ko02000	2.A.7.6	-	-	RhaT
CMS1_k127_3169311_6	880073.Calab_1754	3.554e-05	49.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,2NQ6Y@2323|unclassified Bacteria	2|Bacteria	M	PKD domain	-	-	3.2.1.4,3.4.21.66	ko:K01179,ko:K08651	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	GH5,GH9	-	Autotransporter,PKD,Peptidase_S8,Peptidase_S8_N,fn3
CMS1_k127_3200829_0	156889.Mmc1_2548	9.969e-131	426.0	COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria,2U24Y@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Integrase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve,rve_3
CMS1_k127_3200829_2	234267.Acid_3372	3.039e-29	121.0	COG1547@1|root,COG1547@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF309)	ypuF	-	-	ko:K09763	-	-	-	-	ko00000	-	-	-	DUF309
CMS1_k127_3200829_1	1121106.JQKB01000066_gene5190	2.1e-38	148.0	COG2259@1|root,COG2259@2|Bacteria,1N072@1224|Proteobacteria,2UCXT@28211|Alphaproteobacteria,2JTGQ@204441|Rhodospirillales	204441|Rhodospirillales	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
CMS1_k127_3200829_3	909663.KI867149_gene3232	1.194e-16	85.0	29X4W@1|root,30ITV@2|Bacteria,1PD23@1224|Proteobacteria,437WM@68525|delta/epsilon subdivisions,2X36A@28221|Deltaproteobacteria,2MS4K@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF2924)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2924
CMS1_k127_3200829_4	983544.Lacal_2171	1.376e-06	57.0	COG3797@1|root,COG3797@2|Bacteria,4NSKS@976|Bacteroidetes,1I70K@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
CMS1_k127_3209695_7	1547437.LL06_03500	5.467e-22	99.0	COG1024@1|root,COG1024@2|Bacteria,1R3Q4@1224|Proteobacteria,2TRE2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS1_k127_3209695_3	1121441.AUCX01000010_gene274	1.919e-63	227.0	COG1262@1|root,COG4249@1|root,COG1262@2|Bacteria,COG4249@2|Bacteria,1NQ5K@1224|Proteobacteria,42MAT@68525|delta/epsilon subdivisions,2WKY9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Peptidase_C14
CMS1_k127_3209695_0	313612.L8106_17742	3.633e-183	594.0	COG5360@1|root,COG5360@2|Bacteria,1G4V0@1117|Cyanobacteria	1117|Cyanobacteria	S	Heparinase II/III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III,Hepar_II_III_N
CMS1_k127_3209695_6	450851.PHZ_c0812	1.021e-29	123.0	COG3794@1|root,COG3794@2|Bacteria,1QWIK@1224|Proteobacteria,2TWY9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	CHRD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
CMS1_k127_3209695_4	234267.Acid_0388	3.666e-63	230.0	COG2006@1|root,COG2006@2|Bacteria	2|Bacteria	U	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
CMS1_k127_3209695_5	595460.RRSWK_00912	1.644e-33	146.0	COG0526@1|root,COG2834@1|root,COG0526@2|Bacteria,COG2834@2|Bacteria	2|Bacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	VPA0557	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,LolA_like
CMS1_k127_3209695_2	521011.Mpal_1878	8.376e-75	256.0	COG1945@1|root,arCOG04490@2157|Archaea,2XX0H@28890|Euryarchaeota,2N9J2@224756|Methanomicrobia	224756|Methanomicrobia	E	Belongs to the PdaD family	pdaD	-	4.1.1.19	ko:K02626	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PvlArgDC
CMS1_k127_3209695_1	292459.STH2651	3.813e-77	272.0	COG0665@1|root,COG0665@2|Bacteria,1TR1R@1239|Firmicutes	1239|Firmicutes	CE	FAD dependent oxidoreductase	puuB	-	-	ko:K09471	ko00330,ko01100,map00330,map01100	M00136	R07415	RC00062	ko00000,ko00001,ko00002,ko01000	-	-	-	DAO
CMS1_k127_3212211_1	425104.Ssed_1775	1.58e-58	205.0	COG3631@1|root,COG3631@2|Bacteria,1RJ29@1224|Proteobacteria,1S6S3@1236|Gammaproteobacteria,2QC9V@267890|Shewanellaceae	1236|Gammaproteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
CMS1_k127_3212211_0	338969.Rfer_2335	1.853e-232	726.0	COG0277@1|root,COG0277@2|Bacteria,1MUPW@1224|Proteobacteria,2VI8J@28216|Betaproteobacteria,4AD4J@80864|Comamonadaceae	28216|Betaproteobacteria	C	Berberine and berberine like	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
CMS1_k127_3212211_3	1244869.H261_19019	0.0001461	47.0	COG2963@1|root,COG2963@2|Bacteria,1RGZ5@1224|Proteobacteria,2UAIS@28211|Alphaproteobacteria,2JT7W@204441|Rhodospirillales	204441|Rhodospirillales	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
CMS1_k127_3212211_2	1047013.AQSP01000114_gene713	1.45e-07	54.0	2DQN1@1|root,337Q5@2|Bacteria	2|Bacteria	S	Transposase zinc-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Zn_Tnp_IS91
CMS1_k127_3216469_0	56780.SYN_01854	7.434e-69	243.0	COG1204@1|root,COG1204@2|Bacteria,1MW4Z@1224|Proteobacteria,42TK8@68525|delta/epsilon subdivisions,2WQUX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	helicase superfamily c-terminal domain	-	-	-	ko:K03726	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,Helicase_C
CMS1_k127_3216469_1	1068980.ARVW01000001_gene254	7.497e-22	99.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	2.3.1.57	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	M00135	R01154	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7,FR47
CMS1_k127_321673_5	697282.Mettu_0128	1.681e-05	48.0	COG1943@1|root,COG1943@2|Bacteria,1MYD2@1224|Proteobacteria,1S6QY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
CMS1_k127_321673_4	240016.ABIZ01000001_gene279	2.807e-06	51.0	COG4102@1|root,COG4102@2|Bacteria,46UJZ@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CMS1_k127_321673_2	1265503.KB905161_gene2992	4.598e-49	194.0	COG2199@1|root,COG3829@1|root,COG3706@2|Bacteria,COG3829@2|Bacteria,1R7HC@1224|Proteobacteria,1S0C5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Hemerythrin,PAS_3
CMS1_k127_321673_0	477974.Daud_1393	8.422e-216	692.0	COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,247R7@186801|Clostridia,26133@186807|Peptococcaceae	186801|Clostridia	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
CMS1_k127_321673_3	1229172.JQFA01000002_gene3051	1.487e-25	109.0	COG3296@1|root,COG3296@2|Bacteria,1G8MY@1117|Cyanobacteria,1HCFC@1150|Oscillatoriales	1117|Cyanobacteria	S	Domain of unknown function (DUF4870)	-	-	-	ko:K09940	-	-	-	-	ko00000	-	-	-	DUF4870
CMS1_k127_321673_1	243090.RB8745	1.322e-89	319.0	COG1716@1|root,COG2203@1|root,COG2204@1|root,COG1716@2|Bacteria,COG2203@2|Bacteria,COG2204@2|Bacteria,2IYSJ@203682|Planctomycetes	203682|Planctomycetes	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HTH_8,Sigma54_activat,Yop-YscD_cpl
CMS1_k127_321673_6	583355.Caka_0480	1.727e-05	54.0	COG3669@1|root,COG3669@2|Bacteria	2|Bacteria	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos
CMS1_k127_3218191_5	926692.AZYG01000061_gene1394	3.875e-30	139.0	COG3210@1|root,COG3210@2|Bacteria,1UJPN@1239|Firmicutes,25FF8@186801|Clostridia	186801|Clostridia	U	endoglucanase-related protein, glucosyl hydrolase family 9 protein K01238	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Flg_new
CMS1_k127_3218191_6	1047013.AQSP01000076_gene1470	5.04e-21	98.0	COG3385@1|root,COG3385@2|Bacteria,2NRDU@2323|unclassified Bacteria	2|Bacteria	L	Transposase DDE domain group 1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
CMS1_k127_3218191_4	572546.Arcpr_0321	5.408e-31	136.0	COG0392@1|root,arCOG00897@2157|Archaea,2XT65@28890|Euryarchaeota,246JX@183980|Archaeoglobi	183980|Archaeoglobi	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	Glycos_transf_2,LPG_synthase_TM
CMS1_k127_3218191_3	247156.NFA_19810	2.3e-34	139.0	COG0500@1|root,COG2226@2|Bacteria,2HHMP@201174|Actinobacteria,4FZ7I@85025|Nocardiaceae	201174|Actinobacteria	Q	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	MetW
CMS1_k127_3218191_2	321327.CYA_0238	1.055e-41	168.0	COG0500@1|root,COG0500@2|Bacteria,1G9T2@1117|Cyanobacteria,1H1AQ@1129|Synechococcus	1117|Cyanobacteria	Q	similarity to GB CAH39666.1	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
CMS1_k127_3218191_0	489825.LYNGBM3L_45070	8.473e-172	546.0	COG0399@1|root,COG0399@2|Bacteria,1G47X@1117|Cyanobacteria,1H9EC@1150|Oscillatoriales	1117|Cyanobacteria	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
CMS1_k127_3218191_7	1121448.DGI_3433	3.303e-10	64.0	COG1216@1|root,COG1216@2|Bacteria,1R50T@1224|Proteobacteria,42P74@68525|delta/epsilon subdivisions,2WK88@28221|Deltaproteobacteria,2MANJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_23
CMS1_k127_3218191_1	313628.LNTAR_11846	7.191e-76	270.0	COG2327@1|root,COG2327@2|Bacteria	2|Bacteria	S	slime layer polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PS_pyruv_trans
CMS1_k127_3218191_8	861360.AARI_27410	0.0004832	49.0	COG0673@1|root,COG0673@2|Bacteria,2GK0F@201174|Actinobacteria,1WAID@1268|Micrococcaceae	201174|Actinobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_3222184_6	1396141.BATP01000042_gene1908	2.411e-69	239.0	COG1765@1|root,COG1765@2|Bacteria	2|Bacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
CMS1_k127_3222184_1	443143.GM18_0341	6.044e-291	913.0	COG2133@1|root,COG2133@2|Bacteria,1NRFC@1224|Proteobacteria,42YAV@68525|delta/epsilon subdivisions,2WTUF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3222184_0	382464.ABSI01000011_gene2334	0.0	1263.0	COG3696@1|root,COG3696@2|Bacteria,46USJ@74201|Verrucomicrobia,2IVD5@203494|Verrucomicrobiae	74201|Verrucomicrobia	P	AcrB/AcrD/AcrF family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
CMS1_k127_3222184_4	237368.SCABRO_03591	8.905e-103	354.0	COG0845@1|root,COG0845@2|Bacteria,2IYDV@203682|Planctomycetes	203682|Planctomycetes	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
CMS1_k127_3222184_5	472759.Nhal_1652	1.098e-78	282.0	COG1538@1|root,COG1538@2|Bacteria,1NEZC@1224|Proteobacteria,1S1F9@1236|Gammaproteobacteria,1X1BJ@135613|Chromatiales	135613|Chromatiales	MU	PFAM Outer membrane efflux protein	-	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
CMS1_k127_3222184_2	1121403.AUCV01000014_gene4604	8.123e-176	574.0	COG3420@1|root,COG3420@2|Bacteria,1NIRV@1224|Proteobacteria	1224|Proteobacteria	P	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
CMS1_k127_3222184_3	616991.JPOO01000003_gene62	4.988e-114	381.0	COG2133@1|root,COG2133@2|Bacteria,4NG3Q@976|Bacteroidetes,1I7ZP@117743|Flavobacteriia	976|Bacteroidetes	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CMS1_k127_3232399_0	1521187.JPIM01000026_gene1151	1.436e-07	64.0	COG1277@1|root,COG1277@2|Bacteria,2G9YA@200795|Chloroflexi,37791@32061|Chloroflexia	32061|Chloroflexia	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
CMS1_k127_3232399_1	595460.RRSWK_00292	2.337e-07	63.0	COG1277@1|root,COG1277@2|Bacteria,2IY6H@203682|Planctomycetes	203682|Planctomycetes	CP	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
CMS1_k127_3249373_0	530564.Psta_4021	6.394e-11	76.0	COG1277@1|root,COG1277@2|Bacteria,2IY6H@203682|Planctomycetes	203682|Planctomycetes	CP	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
CMS1_k127_3252990_0	484770.UFO1_2838	1.836e-179	580.0	COG0243@1|root,COG0243@2|Bacteria,1TPZG@1239|Firmicutes,4H4MY@909932|Negativicutes	909932|Negativicutes	C	Anaerobic dimethyl sulfoxide reductase, A subunit, DmsA YnfE	-	-	1.8.5.3	ko:K07306	ko00920,map00920	-	R09501	RC02555	ko00000,ko00001,ko01000,ko02000	5.A.3.3	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CMS1_k127_3252990_1	1123251.ATWM01000001_gene707	2.905e-15	77.0	COG0437@1|root,COG0437@2|Bacteria,2I2DV@201174|Actinobacteria,4FF0K@85021|Intrasporangiaceae	201174|Actinobacteria	C	4Fe-4S dicluster domain	dmsB	-	-	ko:K07307	ko00920,map00920	-	R09501	RC02555	ko00000,ko00001,ko02000	5.A.3.3	-	-	Fer4_11,Fer4_3,Fer4_4
CMS1_k127_3258355_1	756272.Plabr_2561	1.065e-171	584.0	COG0492@1|root,COG0492@2|Bacteria,2J52X@203682|Planctomycetes	203682|Planctomycetes	O	secreted protein-putative xanthan lyase related	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
CMS1_k127_3258355_0	886293.Sinac_0921	7.785e-203	676.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	3.2.1.18,3.2.1.4	ko:K01179,ko:K01186	ko00500,ko00511,ko00600,ko01100,ko04142,map00500,map00511,map00600,map01100,map04142	-	R04018,R06200,R11307,R11308	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33,GH5,GH9	-	BNR,BNR_2,CBM_2,RicinB_lectin_2
CMS1_k127_3258355_2	383372.Rcas_2023	1.284e-98	326.0	COG0693@1|root,COG0693@2|Bacteria,2G8B6@200795|Chloroflexi,3770W@32061|Chloroflexia	32061|Chloroflexia	S	TIGRFAM intracellular protease, PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
CMS1_k127_3258355_8	794903.OPIT5_08040	0.0004474	52.0	COG4968@1|root,COG4968@2|Bacteria	794903.OPIT5_08040|-	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3258355_6	1089548.KI783301_gene1885	2.981e-18	92.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,4HB0C@91061|Bacilli,3WE5H@539002|Bacillales incertae sedis	91061|Bacilli	NU	type II secretion system protein E	pilB	-	-	ko:K02243,ko:K02652	-	M00429	-	-	ko00000,ko00002,ko02035,ko02044	3.A.14.1,3.A.15.2	-	-	T2SSE,T2SSE_N
CMS1_k127_3258355_7	246197.MXAN_2924	2.7e-10	70.0	COG0508@1|root,COG0508@2|Bacteria	2|Bacteria	C	S-acyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,E3_binding,T2SSE_N
CMS1_k127_3258355_3	765912.Thimo_2707	1.806e-85	289.0	COG0500@1|root,COG2226@2|Bacteria,1RF5Y@1224|Proteobacteria,1S57V@1236|Gammaproteobacteria,1X0H8@135613|Chromatiales	135613|Chromatiales	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3258355_4	504472.Slin_0115	1.762e-70	247.0	COG1082@1|root,COG1082@2|Bacteria,4NI4H@976|Bacteroidetes,47MMY@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS1_k127_3258355_5	329726.AM1_2826	5.296e-36	147.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	yprA	-	3.4.11.19	ko:K01266,ko:K07052	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Abi
CMS1_k127_3258766_1	756272.Plabr_2643	9.591e-103	339.0	COG0189@1|root,COG0490@1|root,COG0189@2|Bacteria,COG0490@2|Bacteria,2IYT1@203682|Planctomycetes	203682|Planctomycetes	HJ	COG0189 Glutathione synthase Ribosomal protein S6 modification	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016874,GO:0016879,GO:0016881,GO:0018169,GO:0018410,GO:0019538,GO:0031668,GO:0033554,GO:0036211,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0070739,GO:0071496,GO:0071704,GO:0140096,GO:1901564	-	ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RimK,TrkA_C
CMS1_k127_3258766_8	290397.Adeh_2132	2.992e-11	70.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,439EA@68525|delta/epsilon subdivisions,2X4PC@28221|Deltaproteobacteria,2YZCI@29|Myxococcales	28221|Deltaproteobacteria	K	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
CMS1_k127_3258766_4	395493.BegalDRAFT_0060	4.159e-46	172.0	COG0864@1|root,COG0864@2|Bacteria,1RK4R@1224|Proteobacteria,1S44Q@1236|Gammaproteobacteria,463JT@72273|Thiotrichales	72273|Thiotrichales	K	NikR C terminal nickel binding domain	-	-	-	-	-	-	-	-	-	-	-	-	NikR_C,RHH_1
CMS1_k127_3258766_0	1429851.X548_03040	1.167e-103	347.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,1RNIR@1236|Gammaproteobacteria,1X3CE@135614|Xanthomonadales	135614|Xanthomonadales	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
CMS1_k127_3258766_5	278963.ATWD01000001_gene2970	3.969e-31	138.0	COG0463@1|root,COG0463@2|Bacteria,3Y7A4@57723|Acidobacteria,2JKZK@204432|Acidobacteriia	204432|Acidobacteriia	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS1_k127_3258766_3	880070.Cycma_0098	7.994e-69	252.0	COG1387@1|root,COG1387@2|Bacteria	2|Bacteria	E	zinc ion binding	-	-	3.1.3.15	ko:K02347,ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	PHP
CMS1_k127_3258766_6	56110.Oscil6304_0162	5.308e-29	116.0	COG5428@1|root,COG5428@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2283)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2283
CMS1_k127_3258766_2	880072.Desac_1569	1.395e-70	255.0	COG1893@1|root,COG1893@2|Bacteria,1MX5M@1224|Proteobacteria,43DN9@68525|delta/epsilon subdivisions,2X25J@28221|Deltaproteobacteria,2MS0P@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
CMS1_k127_3262385_1	1142394.PSMK_17230	2.191e-88	311.0	COG1716@1|root,COG2203@1|root,COG4191@1|root,COG1716@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,2IWYR@203682|Planctomycetes	203682|Planctomycetes	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GAF,GAF_2,HATPase_c,Yop-YscD_cpl
CMS1_k127_3262385_0	1209989.TepiRe1_1074	1.34e-296	926.0	COG1111@1|root,COG1205@1|root,COG1111@2|Bacteria,COG1205@2|Bacteria,1TSPA@1239|Firmicutes,248CT@186801|Clostridia,42ERR@68295|Thermoanaerobacterales	186801|Clostridia	L	Domain of unknown function (DUF1998)	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
CMS1_k127_327359_4	314230.DSM3645_21427	8.151e-72	254.0	COG1387@1|root,COG2755@1|root,COG1387@2|Bacteria,COG2755@2|Bacteria,2IXFZ@203682|Planctomycetes	203682|Planctomycetes	E	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CMS1_k127_327359_9	1382359.JIAL01000001_gene2428	1.858e-11	68.0	COG0695@1|root,COG0695@2|Bacteria,3Y58D@57723|Acidobacteria,2JJSP@204432|Acidobacteriia	204432|Acidobacteriia	O	Glutaredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
CMS1_k127_327359_8	338963.Pcar_1073	4.678e-31	134.0	COG0705@1|root,COG0705@2|Bacteria,1PZR3@1224|Proteobacteria,42S2I@68525|delta/epsilon subdivisions,2WNE6@28221|Deltaproteobacteria,43SHU@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
CMS1_k127_327359_3	357808.RoseRS_0062	4.255e-72	255.0	COG0491@1|root,COG0491@2|Bacteria,2GAIA@200795|Chloroflexi,376BC@32061|Chloroflexia	32061|Chloroflexia	S	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS1_k127_327359_5	344747.PM8797T_09709	4.674e-71	247.0	COG3119@1|root,COG3119@2|Bacteria,2IZHX@203682|Planctomycetes	203682|Planctomycetes	P	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_327359_2	1173028.ANKO01000017_gene255	1.538e-77	263.0	COG0431@1|root,COG0431@2|Bacteria,1G0HA@1117|Cyanobacteria,1HAB8@1150|Oscillatoriales	1117|Cyanobacteria	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
CMS1_k127_327359_6	365046.Rta_01620	6.098e-55	196.0	COG0346@1|root,COG0454@1|root,COG0346@2|Bacteria,COG0456@2|Bacteria,1RA6D@1224|Proteobacteria,2VSN2@28216|Betaproteobacteria,4AF8A@80864|Comamonadaceae	28216|Betaproteobacteria	K	FR47-like protein	ypeA	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS1_k127_327359_1	1242864.D187_006315	2.034e-140	456.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,42M67@68525|delta/epsilon subdivisions,2WJQX@28221|Deltaproteobacteria,2YTX6@29|Myxococcales	28221|Deltaproteobacteria	E	Cys Met metabolism	metC	-	2.5.1.48,4.4.1.1	ko:K01739,ko:K01758	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00782,R00999,R01001,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
CMS1_k127_327359_0	1125863.JAFN01000001_gene1462	0.0	1096.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2WJ4J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copF	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase,YHS
CMS1_k127_327359_7	879212.DespoDRAFT_02170	7.529e-42	159.0	COG3431@1|root,COG3431@2|Bacteria,1RJWK@1224|Proteobacteria,42T41@68525|delta/epsilon subdivisions,2WQVM@28221|Deltaproteobacteria,2MKW2@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM Phosphate-starvation-inducible	-	-	-	-	-	-	-	-	-	-	-	-	PsiE
CMS1_k127_327359_10	414684.RC1_2843	6.353e-06	50.0	COG0477@1|root,COG0477@2|Bacteria,1QVYS@1224|Proteobacteria,2TYEU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_3279857_1	857293.CAAU_1802	2.171e-58	209.0	COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,24836@186801|Clostridia,36EDR@31979|Clostridiaceae	186801|Clostridia	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
CMS1_k127_3279857_0	401526.TcarDRAFT_1720	8.906e-250	791.0	COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,4H315@909932|Negativicutes	909932|Negativicutes	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
CMS1_k127_3308384_3	1120931.KB893941_gene1752	1.417e-21	95.0	COG1866@1|root,COG1866@2|Bacteria,1MWXN@1224|Proteobacteria,1RPM0@1236|Gammaproteobacteria,1Y742@135625|Pasteurellales	135625|Pasteurellales	F	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
CMS1_k127_3308384_5	1079460.ATTQ01000006_gene3510	0.0001502	52.0	2DXVU@1|root,32V47@2|Bacteria,1R05I@1224|Proteobacteria,2TYJS@28211|Alphaproteobacteria,4BP2G@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Lipid A 3-O-deacylase (PagL)	-	-	-	-	-	-	-	-	-	-	-	-	PagL
CMS1_k127_3308384_0	382464.ABSI01000010_gene3488	5.788e-163	530.0	COG0591@1|root,COG0591@2|Bacteria	2|Bacteria	E	symporter activity	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
CMS1_k127_3308384_2	880070.Cycma_0099	9.949e-65	236.0	COG0657@1|root,COG0657@2|Bacteria	2|Bacteria	I	acetylesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,COesterase
CMS1_k127_3308384_1	1288963.ADIS_1879	2.988e-77	277.0	COG0657@1|root,COG0657@2|Bacteria,4PKDQ@976|Bacteroidetes,47Y9R@768503|Cytophagia	976|Bacteroidetes	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
CMS1_k127_3308384_4	1197130.BAFM01000005_gene1078	1.966e-08	68.0	COG1520@1|root,arCOG02556@2157|Archaea,2XW47@28890|Euryarchaeota,23U0N@183963|Halobacteria	183963|Halobacteria	S	COG1520 FOG WD40-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CMS1_k127_3326453_0	479432.Sros_5685	3.637e-69	243.0	COG2070@1|root,COG2070@2|Bacteria,2I93H@201174|Actinobacteria,4EIEF@85012|Streptosporangiales	201174|Actinobacteria	S	2-Nitropropane dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
CMS1_k127_3326453_1	357808.RoseRS_4112	3.21e-12	74.0	COG0371@1|root,COG0371@2|Bacteria,2G95F@200795|Chloroflexi	200795|Chloroflexi	C	Iron-containing alcohol dehydrogenase	-	-	1.1.1.261	ko:K00096	ko00564,map00564	-	R05679,R05680	RC00029	ko00000,ko00001,ko01000	-	-	-	Fe-ADH_2
CMS1_k127_3327166_8	1499967.BAYZ01000049_gene2752	2.654e-53	214.0	COG3119@1|root,COG3119@2|Bacteria,2NR0Q@2323|unclassified Bacteria	2|Bacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,DUF4976,Sulfatase
CMS1_k127_3327166_2	1123242.JH636434_gene5127	3.565e-93	316.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclease_NS,NHL
CMS1_k127_3327166_1	1121011.AUCB01000042_gene786	9.312e-149	484.0	COG3669@1|root,COG3669@2|Bacteria,4NE74@976|Bacteroidetes,1IG0A@117743|Flavobacteriia,23IC9@178469|Arenibacter	976|Bacteroidetes	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,F5_F8_type_C
CMS1_k127_3327166_6	344747.PM8797T_06275	1.003e-78	276.0	COG0657@1|root,COG0657@2|Bacteria	2|Bacteria	I	acetylesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
CMS1_k127_3327166_7	1158182.KB905020_gene1752	1.096e-54	195.0	2D5VR@1|root,32TJX@2|Bacteria,1RJJR@1224|Proteobacteria,1SA2M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3327166_3	926560.KE387023_gene3131	9.628e-90	304.0	COG1108@1|root,COG1108@2|Bacteria,1WJ32@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	ABC-type Mn2 Zn2 transport systems permease components	-	-	-	ko:K09816	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
CMS1_k127_3327166_5	526227.Mesil_1589	5.322e-84	289.0	COG1121@1|root,COG1121@2|Bacteria,1WIBF@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	COG1121 ABC-type Mn Zn transport systems ATPase component	-	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
CMS1_k127_3327166_4	869210.Marky_0790	2.006e-84	290.0	COG0803@1|root,COG0803@2|Bacteria,1WI8I@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Belongs to the bacterial solute-binding protein 9 family	-	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
CMS1_k127_3327166_9	604331.AUHY01000043_gene2765	1.674e-45	168.0	COG0735@1|root,COG0735@2|Bacteria,1WJYT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
CMS1_k127_3327166_0	335543.Sfum_3773	4.13e-238	759.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42MQJ@68525|delta/epsilon subdivisions,2WJIX@28221|Deltaproteobacteria,2MR3H@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,HMA,Hydrolase
CMS1_k127_3327166_10	1033743.CAES01000002_gene1772	7.898e-26	124.0	COG1520@1|root,COG1520@2|Bacteria,1VQU9@1239|Firmicutes,4HUQ2@91061|Bacilli,26TR7@186822|Paenibacillaceae	2|Bacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	DUF1863,PQQ_2
CMS1_k127_3327314_2	247490.KSU1_C1333	1.426e-17	94.0	COG4968@1|root,COG4968@2|Bacteria,2J519@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CMS1_k127_3327314_0	886293.Sinac_1268	4.837e-247	787.0	COG1554@1|root,COG1554@2|Bacteria	2|Bacteria	G	hydrolase, family 65, central catalytic	-	-	3.2.1.51	ko:K15923	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	GH95	-	Glyco_hyd_65N_2
CMS1_k127_3328423_0	351746.Pput_5142	1.621e-80	273.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RNKF@1236|Gammaproteobacteria,1YV5K@136845|Pseudomonas putida group	1236|Gammaproteobacteria	P	Ammonium transporter	amtB	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
CMS1_k127_3328423_1	1121035.AUCH01000001_gene2049	2.974e-48	175.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2VSEZ@28216|Betaproteobacteria,2KWKR@206389|Rhodocyclales	206389|Rhodocyclales	K	Belongs to the P(II) protein family	glnB	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
CMS1_k127_3328423_2	631362.Thi970DRAFT_01507	1.459e-06	57.0	COG0640@1|root,COG0640@2|Bacteria,1R18C@1224|Proteobacteria,1T4WH@1236|Gammaproteobacteria,1WZNX@135613|Chromatiales	135613|Chromatiales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3330617_0	1396141.BATP01000034_gene4232	2.972e-96	336.0	COG0591@1|root,COG0591@2|Bacteria,46XE4@74201|Verrucomicrobia,2IVMU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
CMS1_k127_3330617_1	883126.HMPREF9710_02348	3.44e-05	48.0	COG3119@1|root,COG3119@2|Bacteria,1MV92@1224|Proteobacteria,2VIFW@28216|Betaproteobacteria,476YT@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	Sulfatase	atsA	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
CMS1_k127_3334275_1	886293.Sinac_5681	6.329e-86	294.0	COG2010@1|root,COG2319@1|root,COG2010@2|Bacteria,COG2319@2|Bacteria,2IXJX@203682|Planctomycetes	203682|Planctomycetes	C	WD-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,WD40
CMS1_k127_3334275_0	1303518.CCALI_01506	2.201e-95	337.0	COG3934@1|root,COG3934@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.4	ko:K01179,ko:K13276	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	GH5,GH9	-	Cellulase,DUF5060,F5_F8_type_C,FIVAR
CMS1_k127_334711_7	1265505.ATUG01000001_gene4678	9.631e-28	123.0	COG0584@1|root,COG1409@1|root,COG0584@2|Bacteria,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD,GDPD_2,Metallophos,Pur_ac_phosph_N
CMS1_k127_334711_10	1267535.KB906767_gene4121	0.0006472	53.0	COG1501@1|root,COG1501@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Melibiase
CMS1_k127_334711_6	344747.PM8797T_03609	6.598e-46	173.0	COG0558@1|root,COG0558@2|Bacteria	2|Bacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.39	ko:K17884	-	-	R10464	RC00002,RC00078	ko00000,ko01000	-	-	-	CDP-OH_P_transf
CMS1_k127_334711_2	717231.Flexsi_1202	1.234e-118	413.0	COG1283@1|root,COG1283@2|Bacteria,2GEY7@200930|Deferribacteres	200930|Deferribacteres	P	Na+/Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
CMS1_k127_334711_11	1957.JODX01000003_gene4812	0.0009364	51.0	COG1053@1|root,COG1413@1|root,COG1053@2|Bacteria,COG1413@2|Bacteria,2GPN8@201174|Actinobacteria	201174|Actinobacteria	C	fumarate reductase	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Cohesin_HEAT,FAD_binding_2,HEAT_2,Succ_DH_flav_C
CMS1_k127_334711_4	1487921.DP68_14120	1.215e-56	209.0	COG1082@1|root,COG1082@2|Bacteria,1UITG@1239|Firmicutes,25FCS@186801|Clostridia	186801|Clostridia	G	Xylose isomerase-like TIM barrel	-	-	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
CMS1_k127_334711_1	880072.Desac_0015	2.503e-179	578.0	COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,42NA6@68525|delta/epsilon subdivisions,2WIMU@28221|Deltaproteobacteria,2MQ6V@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
CMS1_k127_334711_9	316067.Geob_3428	0.0001119	55.0	COG0457@1|root,COG0457@2|Bacteria	316067.Geob_3428|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_334711_0	314230.DSM3645_11851	6.417e-192	616.0	COG0471@1|root,COG0471@2|Bacteria,2IWY9@203682|Planctomycetes	203682|Planctomycetes	P	COG0471 Di- and tricarboxylate	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
CMS1_k127_334711_3	1123277.KB893172_gene474	6.826e-115	389.0	COG5434@1|root,COG5434@2|Bacteria,4NFSC@976|Bacteroidetes,47Q1K@768503|Cytophagia	976|Bacteroidetes	M	Pectate lyase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_28,Pectate_lyase_3
CMS1_k127_334711_5	1157490.EL26_15670	3.416e-49	184.0	COG0321@1|root,COG0321@2|Bacteria,1V44P@1239|Firmicutes,4HH4H@91061|Bacilli,279KG@186823|Alicyclobacillaceae	91061|Bacilli	H	Biotin/lipoate A/B protein ligase family	lipB	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
CMS1_k127_334711_8	1288963.ADIS_0490	4.353e-10	73.0	COG3934@1|root,COG3934@2|Bacteria,4NF13@976|Bacteroidetes,47NYJ@768503|Cytophagia	976|Bacteroidetes	G	Domain of unknown function (DUF4091)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4091
CMS1_k127_3357217_7	756272.Plabr_2335	6.001e-12	74.0	COG2755@1|root,COG2755@2|Bacteria,2IYGD@203682|Planctomycetes	203682|Planctomycetes	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS1_k127_3357217_3	1499967.BAYZ01000095_gene4190	5.846e-78	266.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	CBM9_2,HATPase_c,HisKA,Response_reg
CMS1_k127_3357217_5	765420.OSCT_1252	2.986e-26	120.0	COG5662@1|root,COG5662@2|Bacteria,2GBKH@200795|Chloroflexi,3781H@32061|Chloroflexia	32061|Chloroflexia	K	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
CMS1_k127_3357217_6	545695.TREAZ_3613	9.435e-26	120.0	COG0407@1|root,COG0407@2|Bacteria	2|Bacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
CMS1_k127_3357217_4	742725.HMPREF9450_00995	1.383e-52	193.0	COG3254@1|root,COG3254@2|Bacteria,4NQQ9@976|Bacteroidetes,2FTDQ@200643|Bacteroidia	976|Bacteroidetes	G	L-rhamnose mutarotase	-	-	5.1.3.32	ko:K03534	-	-	R10819	RC00563	ko00000,ko01000	-	-	-	rhaM
CMS1_k127_3357217_1	1232453.BAIF02000051_gene984	7.215e-105	352.0	COG0407@1|root,COG0407@2|Bacteria,1V2TK@1239|Firmicutes,24FVW@186801|Clostridia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
CMS1_k127_3357217_0	706587.Desti_1275	4.575e-190	606.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42M5F@68525|delta/epsilon subdivisions,2WJ1T@28221|Deltaproteobacteria,2MRHS@213462|Syntrophobacterales	1224|Proteobacteria	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	2.7.7.58,6.2.1.3,6.2.1.34,6.3.2.14	ko:K00666,ko:K01897,ko:K02363,ko:K12508	ko00061,ko00071,ko01053,ko01100,ko01110,ko01130,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01053,map01100,map01110,map01130,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280,R07644	RC00004,RC00014,RC00162,RC03046	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
CMS1_k127_3357217_2	706587.Desti_1274	6.127e-90	306.0	COG2030@1|root,COG2030@2|Bacteria,1RC8D@1224|Proteobacteria,42R40@68525|delta/epsilon subdivisions,2WMNV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N,MaoC_dehydratas
CMS1_k127_3357217_8	1173026.Glo7428_2690	8.79e-05	45.0	COG1028@1|root,COG1028@2|Bacteria,1G67A@1117|Cyanobacteria	1117|Cyanobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS1_k127_3362869_0	452637.Oter_3509	5.494e-82	291.0	COG0673@1|root,COG0673@2|Bacteria,46TMZ@74201|Verrucomicrobia,3K8Y2@414999|Opitutae	414999|Opitutae	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_3362869_1	1288963.ADIS_0530	1.04e-37	147.0	COG1082@1|root,COG1082@2|Bacteria,4NJJZ@976|Bacteroidetes,47PI6@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS1_k127_3364388_1	351016.RAZWK3B_14554	3.768e-17	92.0	COG4227@1|root,COG4227@2|Bacteria,1RDMV@1224|Proteobacteria,2URIY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Pfam:DUF955	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M78
CMS1_k127_3364388_0	886293.Sinac_5899	1.588e-44	169.0	COG4584@1|root,COG4584@2|Bacteria,2J4C3@203682|Planctomycetes	203682|Planctomycetes	L	PFAM Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
CMS1_k127_3366236_0	316067.Geob_0618	1.704e-196	643.0	COG1199@1|root,COG2003@1|root,COG1199@2|Bacteria,COG2003@2|Bacteria,1MVCU@1224|Proteobacteria,42N57@68525|delta/epsilon subdivisions,2WJ82@28221|Deltaproteobacteria,43U02@69541|Desulfuromonadales	28221|Deltaproteobacteria	KL	HELICc2	dinG	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,RadC,ResIII
CMS1_k127_3366236_8	1219080.VEZ01S_02_00610	8.544e-22	102.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1T1Y4@1236|Gammaproteobacteria,1XTDR@135623|Vibrionales	135623|Vibrionales	T	Histidine kinase	chiS	-	-	ko:K19694	-	-	-	-	ko00000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_8,Response_reg
CMS1_k127_3366236_6	1121422.AUMW01000024_gene286	4.095e-69	268.0	COG0642@1|root,COG3829@1|root,COG4191@1|root,COG5002@1|root,COG2205@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,COG5002@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,264H3@186807|Peptococcaceae	186801|Clostridia	T	Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Fe_hyd_lg_C,GAF_2,HATPase_c,HisKA,PAS_9,Response_reg,dCache_3,sCache_3_3
CMS1_k127_3366236_5	935948.KE386494_gene751	6.639e-91	322.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,42FVZ@68295|Thermoanaerobacterales	186801|Clostridia	P	ABC transporter, transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS1_k127_3366236_2	309807.SRU_2163	1.68e-149	497.0	COG1132@1|root,COG1132@2|Bacteria,4NEAG@976|Bacteroidetes,1FIQC@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	V	ABC transporter transmembrane region	-	-	-	ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
CMS1_k127_3366236_1	1123508.JH636443_gene5031	1.317e-168	541.0	COG5434@1|root,COG5434@2|Bacteria,2IX4K@203682|Planctomycetes	203682|Planctomycetes	M	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
CMS1_k127_3366236_7	526227.Mesil_0179	6.122e-56	203.0	COG0637@1|root,COG0637@2|Bacteria,1WJ5Z@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
CMS1_k127_3366236_4	382464.ABSI01000022_gene488	4.584e-97	328.0	COG0560@1|root,COG0560@2|Bacteria,46UCT@74201|Verrucomicrobia,2ITII@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Phosphoserine phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
CMS1_k127_3366236_3	755178.Cyan10605_0314	9.076e-106	350.0	COG1453@1|root,COG1453@2|Bacteria,1G1CE@1117|Cyanobacteria	1117|Cyanobacteria	S	aldo keto reductase family	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red
CMS1_k127_3376445_0	443143.GM18_3669	2.582e-304	962.0	COG0366@1|root,COG0366@2|Bacteria,1PDXT@1224|Proteobacteria,42MZ1@68525|delta/epsilon subdivisions,2WMHA@28221|Deltaproteobacteria,43U2K@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	PFAM alpha amylase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase
CMS1_k127_3376445_4	518766.Rmar_1270	2.092e-88	302.0	COG0240@1|root,COG0240@2|Bacteria,4NF4R@976|Bacteroidetes,1FIU2@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	I	glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
CMS1_k127_3376445_6	530564.Psta_1462	7.291e-17	95.0	COG0699@1|root,COG0699@2|Bacteria,2J426@203682|Planctomycetes	203682|Planctomycetes	S	Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
CMS1_k127_3376445_1	1123073.KB899242_gene926	1.735e-262	824.0	COG3320@1|root,COG4221@1|root,COG3320@2|Bacteria,COG4221@2|Bacteria,1QSHC@1224|Proteobacteria,1RQP8@1236|Gammaproteobacteria,1X3FH@135614|Xanthomonadales	135614|Xanthomonadales	Q	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_4,adh_short
CMS1_k127_3376445_3	502025.Hoch_4295	3.798e-98	331.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,42MDR@68525|delta/epsilon subdivisions,2WKUR@28221|Deltaproteobacteria,2YYA3@29|Myxococcales	28221|Deltaproteobacteria	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS1_k127_3376445_5	1121012.AUKX01000029_gene942	4.141e-61	226.0	COG1409@1|root,COG1409@2|Bacteria,4PIW2@976|Bacteroidetes,1IE6V@117743|Flavobacteriia,23HX3@178469|Arenibacter	976|Bacteroidetes	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
CMS1_k127_3376445_2	1232410.KI421428_gene1190	2.569e-98	329.0	COG0476@1|root,COG0476@2|Bacteria,1R87S@1224|Proteobacteria,42R16@68525|delta/epsilon subdivisions,2WNMW@28221|Deltaproteobacteria,43RZK@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	ThiS-like ubiquitin	-	-	2.7.7.73	ko:K03148	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	Prok-JAB,ThiF,ThiS-like
CMS1_k127_3379586_6	1379698.RBG1_1C00001G0517	2.498e-103	351.0	COG0489@1|root,COG0489@2|Bacteria,2NNX1@2323|unclassified Bacteria	2|Bacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
CMS1_k127_3379586_26	1056512.D515_04336	5.922e-15	79.0	2CBRY@1|root,33DAH@2|Bacteria,1ND9T@1224|Proteobacteria,1SG4C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3379586_27	1123242.JH636437_gene5987	8.709e-13	82.0	COG4219@1|root,COG4219@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Peptidase_M56,TonB_C
CMS1_k127_3379586_9	861299.J421_1183	1.773e-82	287.0	COG0429@1|root,COG0429@2|Bacteria,1ZSTN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	alpha/beta hydrolase fold	-	-	-	ko:K07019	-	-	-	-	ko00000	-	-	-	Abhydrolase_1
CMS1_k127_3379586_12	234267.Acid_5521	2.837e-61	222.0	COG0500@1|root,COG2226@2|Bacteria,3Y8V7@57723|Acidobacteria	57723|Acidobacteria	Q	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3379586_1	1120973.AQXL01000135_gene1394	1.98e-156	505.0	COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,4HAIS@91061|Bacilli,27884@186823|Alicyclobacillaceae	91061|Bacilli	L	MgsA AAA+ ATPase C terminal	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
CMS1_k127_3379586_23	1232437.KL661988_gene214	1.29e-33	136.0	COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,42V4I@68525|delta/epsilon subdivisions,2WRJJ@28221|Deltaproteobacteria,2MKW0@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
CMS1_k127_3379586_20	880073.Calab_0541	1.409e-35	145.0	COG1993@1|root,COG1993@2|Bacteria,2NPXF@2323|unclassified Bacteria	2|Bacteria	T	Uncharacterized ACR, COG1993	-	-	-	ko:K06199,ko:K09137	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CBS,DUF190
CMS1_k127_3379586_7	1403819.BATR01000094_gene2971	2.111e-85	290.0	COG2120@1|root,COG2120@2|Bacteria,46SP2@74201|Verrucomicrobia	74201|Verrucomicrobia	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
CMS1_k127_3379586_24	953739.SVEN_4324	2.745e-32	131.0	COG0350@1|root,COG0350@2|Bacteria,2IFID@201174|Actinobacteria	201174|Actinobacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
CMS1_k127_3379586_14	324602.Caur_0790	1.83e-58	217.0	COG1502@1|root,COG1502@2|Bacteria,2G8RC@200795|Chloroflexi,37519@32061|Chloroflexia	32061|Chloroflexia	I	PFAM phospholipase D Transphosphatidylase	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
CMS1_k127_3379586_21	401526.TcarDRAFT_0419	8.893e-35	141.0	COG0632@1|root,COG0632@2|Bacteria,1V3KF@1239|Firmicutes,4H41W@909932|Negativicutes	909932|Negativicutes	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
CMS1_k127_3379586_3	398767.Glov_2173	1.833e-128	418.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,42M99@68525|delta/epsilon subdivisions,2WJ2Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
CMS1_k127_3379586_28	204669.Acid345_2859	3.201e-05	52.0	COG0745@1|root,COG0745@2|Bacteria	204669.Acid345_2859|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3379586_5	1303518.CCALI_00669	1.207e-121	404.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Glyco_tranf_2_3,Glycos_transf_2,Sulfatase
CMS1_k127_3379586_16	742727.HMPREF9447_03119	8.414e-53	202.0	COG0823@1|root,COG0823@2|Bacteria,4NFQ0@976|Bacteroidetes,2FQKA@200643|Bacteroidia,4ANUE@815|Bacteroidaceae	976|Bacteroidetes	U	Oligogalacturonate lyase	-	-	4.2.2.6	ko:K01730	ko00040,map00040	-	R04382	RC02124,RC02427	ko00000,ko00001,ko01000	-	-	-	PD40,Pectate_lyase22
CMS1_k127_3379586_4	926550.CLDAP_32170	2.043e-123	420.0	COG0613@1|root,COG0613@2|Bacteria	2|Bacteria	Q	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604,DUF5011,SLH
CMS1_k127_3379586_22	179408.Osc7112_5529	2.381e-34	150.0	COG2931@1|root,COG2931@2|Bacteria,1G2XZ@1117|Cyanobacteria,1HEEK@1150|Oscillatoriales	1117|Cyanobacteria	Q	Integrin alpha (beta-propellor repeats).	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_3,DUF4347,FG-GAP_2,VCBS
CMS1_k127_3379586_15	1121468.AUBR01000006_gene387	1.515e-56	222.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,42F3M@68295|Thermoanaerobacterales	186801|Clostridia	T	PFAM ATP-binding region, ATPase domain protein	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
CMS1_k127_3379586_17	1449063.JMLS01000023_gene2827	8.05e-50	194.0	COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,1TSW8@1239|Firmicutes,4HBT1@91061|Bacilli,26U8D@186822|Paenibacillaceae	91061|Bacilli	T	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Hpt,Response_reg
CMS1_k127_3379586_13	933262.AXAM01000058_gene3198	2.606e-60	220.0	COG0575@1|root,COG1408@1|root,COG0575@2|Bacteria,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,42Q51@68525|delta/epsilon subdivisions,2WIMQ@28221|Deltaproteobacteria,2MHZJ@213118|Desulfobacterales	28221|Deltaproteobacteria	I	CDP-archaeol synthase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	CarS-like,Metallophos
CMS1_k127_3379586_10	1120973.AQXL01000121_gene95	4.587e-70	246.0	COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,4H9MU@91061|Bacilli,278I2@186823|Alicyclobacillaceae	91061|Bacilli	J	RNA pseudouridylate synthase	rluB	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
CMS1_k127_3379586_19	292459.STH1802	6.161e-39	153.0	COG1386@1|root,COG1386@2|Bacteria,1V6HI@1239|Firmicutes,24JW7@186801|Clostridia	186801|Clostridia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
CMS1_k127_3379586_2	398767.Glov_2678	8.845e-136	441.0	COG2876@1|root,COG2876@2|Bacteria,1QVAD@1224|Proteobacteria,42MU4@68525|delta/epsilon subdivisions,2WJ8Y@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM DAHP synthetase I KDSA	aroG-2	-	2.5.1.54,5.4.99.5	ko:K03856,ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022,M00024,M00025	R01715,R01826	RC00435,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,DAHP_synth_1
CMS1_k127_3379586_0	316067.Geob_0532	2.745e-296	931.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,42MEQ@68525|delta/epsilon subdivisions,2WIPF@28221|Deltaproteobacteria,43T5A@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Protein of unknown function (DUF3417)	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
CMS1_k127_3379586_18	1123518.ARWI01000001_gene2117	6.439e-42	170.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,1RMXY@1236|Gammaproteobacteria,46048@72273|Thiotrichales	72273|Thiotrichales	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
CMS1_k127_3379586_8	880073.Calab_1352	6.816e-85	285.0	COG0529@1|root,COG0529@2|Bacteria,2NPBJ@2323|unclassified Bacteria	2|Bacteria	P	Catalyzes the synthesis of activated sulfate	cysC	GO:0000096,GO:0000103,GO:0003674,GO:0003824,GO:0004779,GO:0004781,GO:0006082,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010134,GO:0016740,GO:0016772,GO:0016779,GO:0019379,GO:0019419,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0070566,GO:0071704,GO:1901564	2.7.1.25,2.7.7.4	ko:K00860,ko:K00955	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU
CMS1_k127_3379586_11	1267535.KB906767_gene4805	1.18e-63	224.0	COG2258@1|root,COG2258@2|Bacteria,3Y8MZ@57723|Acidobacteria,2JNIF@204432|Acidobacteriia	204432|Acidobacteriia	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
CMS1_k127_3379586_25	1158292.JPOE01000002_gene3598	1.787e-26	110.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,2VH1Q@28216|Betaproteobacteria,1KKA7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS1_k127_3396105_7	237368.SCABRO_03851	1.472e-20	96.0	COG2165@1|root,COG2165@2|Bacteria,2J0Q6@203682|Planctomycetes	203682|Planctomycetes	U	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CMS1_k127_3396105_1	1128421.JAGA01000002_gene1392	4.561e-86	301.0	COG4552@1|root,COG4552@2|Bacteria	2|Bacteria	S	transferase activity, transferring acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_9
CMS1_k127_3396105_5	56110.Oscil6304_5747	5.258e-28	118.0	COG2402@1|root,COG2402@2|Bacteria,1G8Q4@1117|Cyanobacteria,1HDF7@1150|Oscillatoriales	1117|Cyanobacteria	S	contains PIN domain	-	-	-	ko:K07065	-	-	-	-	ko00000	-	-	-	PIN
CMS1_k127_3396105_9	595460.RRSWK_05813	1.975e-17	89.0	COG3809@1|root,COG3809@2|Bacteria	2|Bacteria	S	Transcription factor zinc-finger	-	-	-	ko:K09981	-	-	-	-	ko00000	-	-	-	zf-TFIIB
CMS1_k127_3396105_10	589873.EP13_15725	5.221e-17	90.0	COG0070@1|root,COG0070@2|Bacteria,1NAKQ@1224|Proteobacteria,1SEQ8@1236|Gammaproteobacteria,46AJJ@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	glutamate synthase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3396105_0	765420.OSCT_2094	2.947e-151	492.0	COG0370@1|root,COG0370@2|Bacteria,2GBTA@200795|Chloroflexi,37667@32061|Chloroflexia	32061|Chloroflexia	P	Ferrous iron transport protein B C terminus	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,Gate
CMS1_k127_3396105_2	357808.RoseRS_4511	1.387e-77	274.0	COG0370@1|root,COG0370@2|Bacteria,2GAJB@200795|Chloroflexi,376HM@32061|Chloroflexia	32061|Chloroflexia	P	Ferrous iron transport protein B	-	-	-	-	-	-	-	-	-	-	-	-	FeoB_N
CMS1_k127_3396105_3	765420.OSCT_2424	7.966e-60	214.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,2G6N4@200795|Chloroflexi,375K6@32061|Chloroflexia	32061|Chloroflexia	K	iron dependent repressor	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
CMS1_k127_3396105_4	1317118.ATO8_04206	2.395e-33	141.0	COG0673@1|root,COG0673@2|Bacteria,1MY5N@1224|Proteobacteria,2U0U7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	1.1.1.18,1.1.1.369	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	-	R01183,R09951	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA
CMS1_k127_3396105_6	1322246.BN4_10216	2.057e-23	105.0	COG1259@1|root,COG1259@2|Bacteria,1RFFV@1224|Proteobacteria,42SCI@68525|delta/epsilon subdivisions,2WPWT@28221|Deltaproteobacteria,2M8KC@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
CMS1_k127_3396105_8	661478.OP10G_3516	1.751e-17	87.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961,VCBS
CMS1_k127_3438256_0	1304880.JAGB01000002_gene2262	2.712e-154	493.0	COG0673@1|root,COG0673@2|Bacteria,1U4A4@1239|Firmicutes,249UF@186801|Clostridia	186801|Clostridia	E	PFAM oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_3438256_1	180332.JTGN01000003_gene1997	3.507e-25	118.0	COG0407@1|root,COG0407@2|Bacteria,1VEQ3@1239|Firmicutes,24RQ2@186801|Clostridia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
CMS1_k127_3439017_0	1128421.JAGA01000003_gene2905	2.735e-141	467.0	COG3011@1|root,COG3011@2|Bacteria	2|Bacteria	CH	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	LMF1
CMS1_k127_3439017_2	391625.PPSIR1_19754	1.03e-40	156.0	COG2967@1|root,COG2967@2|Bacteria,1MZ2Z@1224|Proteobacteria,431ED@68525|delta/epsilon subdivisions,2WWZ0@28221|Deltaproteobacteria,2YVD5@29|Myxococcales	28221|Deltaproteobacteria	P	ApaG domain	apaG	-	-	ko:K06195	-	-	-	-	ko00000	-	-	-	DUF525
CMS1_k127_3439017_1	867845.KI911784_gene2158	9.958e-48	183.0	COG1597@1|root,COG1597@2|Bacteria,2G70R@200795|Chloroflexi,375F4@32061|Chloroflexia	32061|Chloroflexia	I	diacylglycerol kinase, catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
CMS1_k127_3442077_0	1209989.TepiRe1_0710	1.181e-165	529.0	COG1402@1|root,COG1402@2|Bacteria,1V0N8@1239|Firmicutes,24BWG@186801|Clostridia	186801|Clostridia	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470,ko:K22232	ko00330,ko00562,map00330,map00562	-	R01884,R11771	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
CMS1_k127_3442077_1	1410624.JNKK01000016_gene2095	1.038e-18	88.0	COG0673@1|root,COG0673@2|Bacteria,1TP83@1239|Firmicutes,248XQ@186801|Clostridia,27TX9@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_3450360_2	1267533.KB906735_gene4473	7.657e-114	380.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3450360_1	686340.Metal_0326	1.134e-195	618.0	COG0677@1|root,COG0677@2|Bacteria,1MUC6@1224|Proteobacteria,1RMX0@1236|Gammaproteobacteria,1XEJF@135618|Methylococcales	135618|Methylococcales	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	-	ko:K02474	ko00520,map00520	-	R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
CMS1_k127_3450360_0	251229.Chro_4813	2.601e-315	980.0	COG1749@1|root,COG1749@2|Bacteria,1GBDW@1117|Cyanobacteria	1117|Cyanobacteria	N	Domain of unknown function (DUF4082)	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF4082
CMS1_k127_3450380_2	243090.RB5969	1.287e-141	466.0	COG0514@1|root,COG0514@2|Bacteria,2IX4R@203682|Planctomycetes	203682|Planctomycetes	L	DEAD DEAH box helicase	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
CMS1_k127_3450380_0	1158294.JOMI01000005_gene3231	9.632e-227	725.0	28JDZ@1|root,2Z988@2|Bacteria,4NHND@976|Bacteroidetes,2FQDQ@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3450380_5	661478.OP10G_1558	4.981e-98	332.0	COG0395@1|root,COG0395@2|Bacteria	2|Bacteria	P	glycerophosphodiester transmembrane transport	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_3450380_4	661478.OP10G_1557	2.985e-106	352.0	COG1175@1|root,COG1175@2|Bacteria	2|Bacteria	P	transmembrane transport	-	-	-	ko:K02025,ko:K10118,ko:K10201,ko:K15771	ko02010,map02010	M00196,M00205,M00207,M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.18,3.A.1.1.2,3.A.1.1.28	-	-	BPD_transp_1,PQQ_2,SBP_bac_1
CMS1_k127_3450380_1	661478.OP10G_1556	5.126e-151	494.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K02027,ko:K10117	ko02010,map02010	M00196,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
CMS1_k127_3450380_3	278957.ABEA03000166_gene4032	1.02e-111	374.0	COG0407@1|root,COG0407@2|Bacteria,46UQR@74201|Verrucomicrobia,3K9WM@414999|Opitutae	414999|Opitutae	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
CMS1_k127_345151_4	391612.CY0110_27535	6.063e-37	143.0	COG0475@1|root,COG0475@2|Bacteria,1GCKS@1117|Cyanobacteria,3KJCE@43988|Cyanothece	1117|Cyanobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
CMS1_k127_345151_0	1056820.KB900663_gene3775	3.061e-185	601.0	COG1297@1|root,COG1297@2|Bacteria,1N7SK@1224|Proteobacteria,1RNC8@1236|Gammaproteobacteria,2PPKQ@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	S	OPT oligopeptide transporter protein	oliA	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0051179,GO:0051234,GO:0055085	-	-	-	-	-	-	-	-	-	-	OPT
CMS1_k127_345151_1	1395571.TMS3_0113945	4.635e-130	430.0	COG2610@1|root,COG2610@2|Bacteria,1N2VU@1224|Proteobacteria,1RNCQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EG	COG2610 H gluconate symporter and related permeases	-	-	-	-	-	-	-	-	-	-	-	-	GntP_permease
CMS1_k127_345151_2	880070.Cycma_2743	2.052e-88	299.0	COG1409@1|root,COG1409@2|Bacteria,4NRDF@976|Bacteroidetes,47VTX@768503|Cytophagia	976|Bacteroidetes	S	Calcineurin-like phosphoesterase superfamily domain	-	-	3.1.3.16	ko:K21814	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	Metallophos
CMS1_k127_345151_5	1223410.KN050846_gene405	4.967e-13	83.0	COG2931@1|root,COG3210@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,4NGEX@976|Bacteroidetes,1HZV9@117743|Flavobacteriia	976|Bacteroidetes	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_345151_3	479434.Sthe_0138	5.642e-54	195.0	COG1404@1|root,COG1404@2|Bacteria,2G7HM@200795|Chloroflexi	200795|Chloroflexi	O	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	ko:K14645,ko:K17734	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
CMS1_k127_3455649_0	1089551.KE386572_gene1301	1.14e-35	147.0	COG0730@1|root,COG0730@2|Bacteria,1MVY3@1224|Proteobacteria,2TU6M@28211|Alphaproteobacteria,4BQEX@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
CMS1_k127_3465264_7	926550.CLDAP_39470	2.079e-33	137.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS1_k127_3465264_10	1506583.JQJY01000008_gene3950	1.018e-21	108.0	COG0823@1|root,COG0823@2|Bacteria,4NFQ0@976|Bacteroidetes,1I7I9@117743|Flavobacteriia,2NSYV@237|Flavobacterium	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	4.2.2.6	ko:K01730	ko00040,map00040	-	R04382	RC02124,RC02427	ko00000,ko00001,ko01000	-	-	-	PD40,Pectate_lyase22
CMS1_k127_3465264_9	1381751.JAJB01000069_gene383	3.532e-28	124.0	COG1555@1|root,COG1555@2|Bacteria,2IQDC@201174|Actinobacteria,4F9TR@85019|Brevibacteriaceae	201174|Actinobacteria	L	Helix-hairpin-helix motif	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
CMS1_k127_3465264_1	502025.Hoch_6505	2.382e-166	532.0	COG0019@1|root,COG0019@2|Bacteria,1MW3T@1224|Proteobacteria,42MVP@68525|delta/epsilon subdivisions,2WITG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Belongs to the Orn Lys Arg decarboxylase class-II family. NspC subfamily	nspC	-	4.1.1.96	ko:K13747	ko00330,ko01100,map00330,map01100	-	R09081,R09082	RC00299	ko00000,ko00001,ko01000	-	-	-	Ala_racemase_N,Orn_DAP_Arg_deC
CMS1_k127_3465264_0	439235.Dalk_4658	1.875e-215	672.0	COG1748@1|root,COG1748@2|Bacteria,1NIU2@1224|Proteobacteria,42MHS@68525|delta/epsilon subdivisions,2WJQW@28221|Deltaproteobacteria,2MHRC@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Saccharopine dehydrogenase	-	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0902	Sacchrp_dh_C,Sacchrp_dh_NADP
CMS1_k127_3465264_5	517417.Cpar_1060	4.747e-70	246.0	COG0846@1|root,COG0846@2|Bacteria,1FEUB@1090|Chlorobi	1090|Chlorobi	K	Silent information regulator protein Sir2	-	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
CMS1_k127_3465264_6	760192.Halhy_4503	6.193e-50	182.0	COG2318@1|root,COG2318@2|Bacteria,4NQEI@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF1572)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1572
CMS1_k127_3465264_4	671143.DAMO_2352	1.457e-88	302.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	yeeZ	-	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase,NAD_binding_10,RmlD_sub_bind
CMS1_k127_3465264_2	1283300.ATXB01000001_gene517	2.431e-132	434.0	COG0438@1|root,COG0438@2|Bacteria,1MUB7@1224|Proteobacteria,1RQYE@1236|Gammaproteobacteria,1XEG4@135618|Methylococcales	135618|Methylococcales	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
CMS1_k127_3465264_11	1121403.AUCV01000017_gene4462	3.658e-18	93.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,42R5H@68525|delta/epsilon subdivisions,2WNZS@28221|Deltaproteobacteria,2MJUT@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Belongs to the ompA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
CMS1_k127_3465264_8	1128427.KB904821_gene190	4.508e-33	140.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G1QI@1117|Cyanobacteria,1H7BP@1150|Oscillatoriales	1117|Cyanobacteria	NU	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_7,TPR_8
CMS1_k127_3465264_3	483216.BACEGG_03642	2.533e-110	370.0	2F0E2@1|root,33TH6@2|Bacteria,4P16Q@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3483975_5	1444309.JAQG01000044_gene3331	0.0005698	51.0	COG0318@1|root,COG0318@2|Bacteria,1V2NE@1239|Firmicutes,4HBPA@91061|Bacilli,26T64@186822|Paenibacillaceae	91061|Bacilli	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3483975_3	1128421.JAGA01000003_gene3247	1.584e-78	287.0	COG2304@1|root,COG2304@2|Bacteria,2NQHG@2323|unclassified Bacteria	2|Bacteria	S	Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
CMS1_k127_3483975_2	886293.Sinac_2614	9.767e-81	278.0	COG1721@1|root,COG1721@2|Bacteria,2IY59@203682|Planctomycetes	203682|Planctomycetes	S	protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CMS1_k127_3483975_1	1192034.CAP_0061	8.676e-125	408.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,42NCX@68525|delta/epsilon subdivisions,2WJUZ@28221|Deltaproteobacteria,2YYCD@29|Myxococcales	28221|Deltaproteobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS1_k127_3483975_0	497964.CfE428DRAFT_5154	4.856e-154	522.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,46U3B@74201|Verrucomicrobia	2|Bacteria	S	Putative glutamine amidotransferase	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,GATase1_like,VWA,VWA_2,VWA_3
CMS1_k127_3483975_4	357808.RoseRS_2986	1.36e-06	50.0	COG3391@1|root,COG3391@2|Bacteria,2GBRT@200795|Chloroflexi,376BG@32061|Chloroflexia	32061|Chloroflexia	S	PA14	-	-	-	-	-	-	-	-	-	-	-	-	NHL,PA14
CMS1_k127_3490304_1	1403819.BATR01000020_gene657	3.058e-17	89.0	COG1595@1|root,COG1595@2|Bacteria,46VNT@74201|Verrucomicrobia,2IVV9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4
CMS1_k127_3490304_0	485917.Phep_0351	4.664e-147	478.0	COG4257@1|root,COG4257@2|Bacteria,4P0GZ@976|Bacteroidetes,1IW5R@117747|Sphingobacteriia	976|Bacteroidetes	V	antibiotic catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3507333_1	314230.DSM3645_21277	9.864e-257	815.0	COG5492@1|root,COG5492@2|Bacteria,2IXP9@203682|Planctomycetes	203682|Planctomycetes	N	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt2,PSD1
CMS1_k127_3507333_4	886293.Sinac_5683	2.734e-164	545.0	COG3064@1|root,COG3064@2|Bacteria,2IWVN@203682|Planctomycetes	203682|Planctomycetes	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	PPC
CMS1_k127_3507333_5	575540.Isop_3526	1.031e-163	526.0	COG4102@1|root,COG4102@2|Bacteria,2IWYX@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CMS1_k127_3507333_3	1157490.EL26_05420	2.528e-174	561.0	COG1418@1|root,COG1418@2|Bacteria,1TP48@1239|Firmicutes,4HC9J@91061|Bacilli,277VR@186823|Alicyclobacillaceae	91061|Bacilli	S	Endoribonuclease that initiates mRNA decay	rny	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
CMS1_k127_3507333_6	338966.Ppro_3311	4.1e-85	289.0	COG1692@1|root,COG1692@2|Bacteria,1MW12@1224|Proteobacteria,42PCG@68525|delta/epsilon subdivisions,2WM8X@28221|Deltaproteobacteria,43TFA@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	YmdB-like protein	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
CMS1_k127_3507333_2	1444309.JAQG01000008_gene1704	5.964e-197	657.0	COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,4HB89@91061|Bacilli,26R07@186822|Paenibacillaceae	91061|Bacilli	D	Required for chromosome condensation and partitioning	smc	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
CMS1_k127_3507333_7	237368.SCABRO_03057	3.793e-69	253.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1
CMS1_k127_3507333_0	1173023.KE650771_gene5224	1.145e-291	944.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1JJIX@1189|Stigonemataceae	1117|Cyanobacteria	Q	Thioesterase domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_12,Methyltransf_25,PP-binding,Thioesterase
CMS1_k127_3510717_20	1304880.JAGB01000002_gene1701	3.897e-39	149.0	COG1397@1|root,COG1397@2|Bacteria,1TSKF@1239|Firmicutes,25DA4@186801|Clostridia	186801|Clostridia	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
CMS1_k127_3510717_27	1347392.CCEZ01000018_gene1095	4.833e-08	63.0	COG0061@1|root,COG0061@2|Bacteria,1TRB3@1239|Firmicutes,24BG6@186801|Clostridia,36EBN@31979|Clostridiaceae	186801|Clostridia	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS05480	NAD_kinase
CMS1_k127_3510717_7	1174504.AJTN02000153_gene1008	2.547e-100	347.0	COG1178@1|root,COG1178@2|Bacteria,1UMPK@1239|Firmicutes,4ITY3@91061|Bacilli,1ZSE6@1386|Bacillus	91061|Bacilli	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
CMS1_k127_3510717_18	335541.Swol_1403	4.273e-43	169.0	COG1639@1|root,COG1639@2|Bacteria,1TPRT@1239|Firmicutes,249CG@186801|Clostridia,42KAI@68298|Syntrophomonadaceae	186801|Clostridia	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD,Response_reg
CMS1_k127_3510717_28	935567.JAES01000025_gene1212	4.476e-05	52.0	COG1826@1|root,COG1826@2|Bacteria,1N73F@1224|Proteobacteria,1SD9K@1236|Gammaproteobacteria,1X84C@135614|Xanthomonadales	135614|Xanthomonadales	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation	tatB	-	-	ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
CMS1_k127_3510717_19	563192.HMPREF0179_03490	3.312e-40	160.0	COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,42MM7@68525|delta/epsilon subdivisions,2WKJW@28221|Deltaproteobacteria,2M9RT@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
CMS1_k127_3510717_24	530564.Psta_3114	1.728e-22	102.0	COG0776@1|root,COG0776@2|Bacteria,2J01P@203682|Planctomycetes	203682|Planctomycetes	L	Belongs to the bacterial histone-like protein family	-	-	-	ko:K03530,ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
CMS1_k127_3510717_9	1007103.AFHW01000156_gene999	1.095e-81	275.0	COG0512@1|root,COG0512@2|Bacteria,1TT9R@1239|Firmicutes,4H9XP@91061|Bacilli,26SGI@186822|Paenibacillaceae	91061|Bacilli	EH	with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine	pabA	-	2.6.1.85,4.1.3.27	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
CMS1_k127_3510717_5	316067.Geob_3440	1.566e-164	532.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,42MXN@68525|delta/epsilon subdivisions,2WJN0@28221|Deltaproteobacteria,43TZF@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657,ko:K13503	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
CMS1_k127_3510717_21	357808.RoseRS_0207	4.828e-37	143.0	COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,2G6YA@200795|Chloroflexi,375HD@32061|Chloroflexia	32061|Chloroflexia	E	Histidine biosynthesis bifunctional protein HisIE	hisI	-	3.5.4.19,3.6.1.31	ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH,PRA-PH
CMS1_k127_3510717_4	643648.Slip_0423	3.172e-165	530.0	COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,25E48@186801|Clostridia,42KID@68298|Syntrophomonadaceae	186801|Clostridia	F	Biotin carboxylase C-terminal domain	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
CMS1_k127_3510717_23	316278.SynRCC307_0032	8.18e-29	122.0	COG0511@1|root,COG0511@2|Bacteria,1G6MY@1117|Cyanobacteria,1GZ7K@1129|Synechococcus	1117|Cyanobacteria	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
CMS1_k127_3510717_13	1232452.BAIB02000006_gene1453	1.436e-66	233.0	COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,249DV@186801|Clostridia,268CB@186813|unclassified Clostridiales	186801|Clostridia	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
CMS1_k127_3510717_8	1487921.DP68_15265	1.26e-91	321.0	COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,247SG@186801|Clostridia,36E1G@31979|Clostridiaceae	186801|Clostridia	E	Belongs to the peptidase M24B family	-	-	3.4.11.9,3.4.13.9	ko:K01262,ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
CMS1_k127_3510717_26	485916.Dtox_4116	6.871e-12	79.0	COG3307@1|root,COG3307@2|Bacteria,1TQGY@1239|Firmicutes,24AB7@186801|Clostridia,261YW@186807|Peptococcaceae	186801|Clostridia	M	PFAM O-Antigen	-	-	-	ko:K18814	-	-	-	-	ko00000,ko02000	9.B.67.1	-	-	Wzy_C
CMS1_k127_3510717_15	1499967.BAYZ01000186_gene3967	8.707e-62	229.0	COG0472@1|root,COG0472@2|Bacteria	1499967.BAYZ01000186_gene3967|-	M	phospho-N-acetylmuramoyl-pentapeptide-transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3510717_10	316274.Haur_0234	4.617e-73	264.0	COG0438@1|root,COG0438@2|Bacteria,2G7TE@200795|Chloroflexi,3750Z@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	2.4.1.348	ko:K12995	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glyco_transf_4,Glycos_transf_1
CMS1_k127_3510717_12	479434.Sthe_0904	3.603e-67	246.0	COG0438@1|root,COG0438@2|Bacteria,2G5PS@200795|Chloroflexi,27XVU@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS1_k127_3510717_14	1521187.JPIM01000017_gene347	1.486e-63	232.0	COG0438@1|root,COG0438@2|Bacteria,2G61I@200795|Chloroflexi,3753V@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS1_k127_3510717_11	243231.GSU0031	1.852e-70	251.0	COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,42MTI@68525|delta/epsilon subdivisions,2WIXW@28221|Deltaproteobacteria,43TH8@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
CMS1_k127_3510717_22	867903.ThesuDRAFT_00680	3.709e-32	134.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,24MQK@186801|Clostridia,3WCM6@538999|Clostridiales incertae sedis	186801|Clostridia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
CMS1_k127_3510717_2	1379698.RBG1_1C00001G1489	6.343e-281	876.0	COG0443@1|root,COG0443@2|Bacteria,2NNU1@2323|unclassified Bacteria	2|Bacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
CMS1_k127_3510717_6	1121918.ARWE01000001_gene3463	1.741e-113	377.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,42KZM@68525|delta/epsilon subdivisions,2WJGP@28221|Deltaproteobacteria,43SEG@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	DnaJ central domain	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
CMS1_k127_3510717_1	289376.THEYE_A1347	0.0	1390.0	COG0085@1|root,COG0085@2|Bacteria,3J0CW@40117|Nitrospirae	40117|Nitrospirae	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
CMS1_k127_3510717_0	671143.DAMO_0533	0.0	1647.0	COG0086@1|root,COG0086@2|Bacteria,2NNPR@2323|unclassified Bacteria	2|Bacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03046,ko:K13797	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
CMS1_k127_3510717_17	82654.Pse7367_1189	3.588e-50	184.0	COG0048@1|root,COG0048@2|Bacteria,1G4ZZ@1117|Cyanobacteria,1HAP5@1150|Oscillatoriales	1117|Cyanobacteria	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
CMS1_k127_3510717_16	546274.EIKCOROL_02426	4.966e-60	211.0	COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,2VQ63@28216|Betaproteobacteria,2KQI9@206351|Neisseriales	206351|Neisseriales	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
CMS1_k127_3510717_3	765910.MARPU_03705	4.395e-271	850.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,1RNSZ@1236|Gammaproteobacteria,1WW0N@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
CMS1_k127_3510717_25	1304880.JAGB01000003_gene1226	1.861e-14	78.0	COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia	186801|Clostridia	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
CMS1_k127_3510741_1	1121904.ARBP01000022_gene3510	1.036e-46	173.0	COG1524@1|root,COG1524@2|Bacteria,4NIUS@976|Bacteroidetes,47NWF@768503|Cytophagia	976|Bacteroidetes	S	type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,PA14,Phosphodiest
CMS1_k127_3510741_0	926569.ANT_07690	6.708e-145	471.0	COG0162@1|root,COG0162@2|Bacteria,2G64J@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
CMS1_k127_3510741_4	1121447.JONL01000001_gene735	6.046e-05	46.0	2EG8N@1|root,33A0G@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3510741_2	1304880.JAGB01000003_gene1212	5.317e-16	78.0	COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia	186801|Clostridia	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
CMS1_k127_3511593_1	234267.Acid_5423	2.24e-44	162.0	COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,3Y4NM@57723|Acidobacteria	57723|Acidobacteria	C	Fumarate hydratase (Fumerase)	-	-	4.2.1.2	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
CMS1_k127_3511593_0	663610.JQKO01000016_gene1606	4.63e-87	302.0	COG2706@1|root,COG2706@2|Bacteria,1NG69@1224|Proteobacteria,2UZGA@28211|Alphaproteobacteria,3NCBV@45404|Beijerinckiaceae	28211|Alphaproteobacteria	G	Lactonase, 7-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
CMS1_k127_3511593_2	1227352.C173_22317	6.41e-13	69.0	COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,4HB4P@91061|Bacilli,26SCI@186822|Paenibacillaceae	91061|Bacilli	T	Histidine kinase	hssS	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
CMS1_k127_3515299_6	886293.Sinac_3371	1.103e-22	111.0	COG2010@1|root,COG2010@2|Bacteria,2IYIY@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
CMS1_k127_3515299_3	880526.KE386488_gene1576	7.487e-92	336.0	COG0823@1|root,COG0823@2|Bacteria,4NIGD@976|Bacteroidetes,2G2P7@200643|Bacteroidia	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3515299_1	583355.Caka_3039	4.737e-164	535.0	COG1858@1|root,COG3391@1|root,COG1858@2|Bacteria,COG3391@2|Bacteria,46UC1@74201|Verrucomicrobia,3K9FB@414999|Opitutae	414999|Opitutae	C	TIGRFAM 40-residue YVTN family beta-propeller repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3515299_5	349741.Amuc_1932	1.14e-64	231.0	COG0251@1|root,COG0251@2|Bacteria,46V5Y@74201|Verrucomicrobia,2IW47@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
CMS1_k127_3515299_0	1291050.JAGE01000001_gene867	4.353e-181	597.0	COG0823@1|root,COG0823@2|Bacteria,1VP24@1239|Firmicutes,24WTQ@186801|Clostridia,3WN5Z@541000|Ruminococcaceae	186801|Clostridia	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
CMS1_k127_3515299_2	536019.Mesop_2083	6.604e-143	476.0	2F5ED@1|root,33Y06@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4838)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4838
CMS1_k127_3515299_4	97139.C824_01928	1.659e-79	276.0	COG0673@1|root,COG0673@2|Bacteria,1TP83@1239|Firmicutes,248XQ@186801|Clostridia,36F4R@31979|Clostridiaceae	186801|Clostridia	S	Oxidoreductase family, C-terminal alpha beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_3535651_2	1267534.KB906759_gene1972	1.576e-09	69.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	hao	-	1.7.2.6	ko:K10535	ko00910,ko01120,map00910,map01120	M00528,M00804	R10164	RC00383	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrome_C554,Cytochrome_CBB3,Multi-haem_cyto,Paired_CXXCH_1
CMS1_k127_3535651_0	1121920.AUAU01000018_gene1826	5.762e-142	465.0	COG3005@1|root,COG3005@2|Bacteria,3Y3MU@57723|Acidobacteria	57723|Acidobacteria	C	NapC/NirT cytochrome c family, N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_NNT
CMS1_k127_3553286_0	504472.Slin_5658	4.374e-55	209.0	COG2366@1|root,COG2366@2|Bacteria,4NEIX@976|Bacteroidetes,47JRC@768503|Cytophagia	976|Bacteroidetes	S	PFAM peptidase S45 penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
CMS1_k127_3553286_1	344747.PM8797T_16018	1.748e-43	172.0	COG1621@1|root,COG1621@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 32 family	-	-	3.2.1.26,3.2.1.65	ko:K01193,ko:K01212	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R00802,R02410,R03635,R03921,R05624,R06088,R11311	RC00028,RC00077,RC03278	ko00000,ko00001,ko01000	-	GH32	-	Glyco_hydro_32N,Glyco_hydro_43
CMS1_k127_3553286_2	996637.SGM_0156	1.388e-17	96.0	COG1082@1|root,COG1470@1|root,COG1082@2|Bacteria,COG1470@2|Bacteria,2GKFD@201174|Actinobacteria	201174|Actinobacteria	G	Glycoside hydrolase 97	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	GH97_C,GH97_N,Glyco_hydro_97,NPCBM,NPCBM_assoc,RicinB_lectin_2
CMS1_k127_3558494_0	886293.Sinac_2223	1.457e-319	1014.0	COG2010@1|root,COG2010@2|Bacteria,2IYC4@203682|Planctomycetes	203682|Planctomycetes	C	Protein of unknown function (DUF1549)	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
CMS1_k127_3558494_1	886293.Sinac_2222	4.946e-223	700.0	COG4102@1|root,COG4102@2|Bacteria,2J4YY@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CMS1_k127_3558494_3	760568.Desku_3214	1.189e-39	154.0	COG5483@1|root,COG5483@2|Bacteria,1V4SJ@1239|Firmicutes,24A6M@186801|Clostridia	186801|Clostridia	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
CMS1_k127_3558494_2	886293.Sinac_2222	4.449e-65	226.0	COG4102@1|root,COG4102@2|Bacteria,2J4YY@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CMS1_k127_359738_5	1380600.AUYN01000009_gene1523	5.169e-27	117.0	COG3540@1|root,COG3540@2|Bacteria,4NFXQ@976|Bacteroidetes,1HY2S@117743|Flavobacteriia	976|Bacteroidetes	P	PhoD-like phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	PhoD
CMS1_k127_359738_6	1380356.JNIK01000014_gene3330	1.754e-23	111.0	COG1621@1|root,COG1621@2|Bacteria,2GKT1@201174|Actinobacteria,4ESGV@85013|Frankiales	201174|Actinobacteria	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_359738_0	489825.LYNGBM3L_30390	2.875e-264	825.0	COG4147@1|root,COG4147@2|Bacteria,1G197@1117|Cyanobacteria,1H6X7@1150|Oscillatoriales	1117|Cyanobacteria	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
CMS1_k127_359738_4	686578.AFFX01000003_gene307	7.618e-30	122.0	COG4327@1|root,COG4327@2|Bacteria,1N0TK@1224|Proteobacteria,1S8V9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF4212
CMS1_k127_359738_7	1249634.D781_2674	0.0001197	55.0	COG3934@1|root,COG3934@2|Bacteria,1QVN8@1224|Proteobacteria,1RUKS@1236|Gammaproteobacteria,402VC@613|Serratia	1236|Gammaproteobacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_359738_8	314285.KT71_09307	0.0002242	50.0	2E2JB@1|root,32XNT@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_359738_2	748449.Halha_2398	2.104e-50	189.0	COG1216@1|root,COG1216@2|Bacteria,1UIHC@1239|Firmicutes,25F9A@186801|Clostridia,3WADS@53433|Halanaerobiales	186801|Clostridia	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS1_k127_359738_1	1340493.JNIF01000003_gene1832	7.97e-130	422.0	COG0620@1|root,COG0620@2|Bacteria	2|Bacteria	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
CMS1_k127_359738_3	1267535.KB906767_gene1026	4.141e-42	166.0	COG0673@1|root,COG0673@2|Bacteria,3Y6VS@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_3601168_1	665571.STHERM_c07830	6.317e-156	507.0	COG2021@1|root,COG2021@2|Bacteria,2JA6P@203691|Spirochaetes	203691|Spirochaetes	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metXA	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
CMS1_k127_3601168_0	1232410.KI421413_gene795	1.106e-198	627.0	COG2873@1|root,COG2873@2|Bacteria,1NQME@1224|Proteobacteria,43DRR@68525|delta/epsilon subdivisions,2X70U@28221|Deltaproteobacteria,43S7X@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Cys/Met metabolism PLP-dependent enzyme	metY-1	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
CMS1_k127_3601168_2	1313304.CALK_0073	8.753e-139	447.0	COG0031@1|root,COG0031@2|Bacteria	2|Bacteria	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009333,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b2414,iAPECO1_1312.APECO1_4131,iB21_1397.B21_02275,iBWG_1329.BWG_2176,iE2348C_1286.E2348C_2600,iEC042_1314.EC042_2623,iEC55989_1330.EC55989_2704,iECABU_c1320.ECABU_c27350,iECBD_1354.ECBD_1267,iECB_1328.ECB_02314,iECDH10B_1368.ECDH10B_2579,iECDH1ME8569_1439.ECDH1ME8569_2348,iECD_1391.ECD_02314,iECED1_1282.ECED1_2858,iECH74115_1262.ECH74115_3645,iECIAI1_1343.ECIAI1_2472,iECNA114_1301.ECNA114_2491,iECO103_1326.ECO103_2933,iECO111_1330.ECO111_3144,iECO26_1355.ECO26_3467,iECOK1_1307.ECOK1_2731,iECP_1309.ECP_2438,iECS88_1305.ECS88_2604,iECSE_1348.ECSE_2705,iECSF_1327.ECSF_2278,iECSP_1301.ECSP_3362,iECUMN_1333.ECUMN_2736,iECW_1372.ECW_m2643,iECs_1301.ECs3286,iEKO11_1354.EKO11_1314,iETEC_1333.ETEC_2527,iEcDH1_1363.EcDH1_1247,iEcHS_1320.EcHS_A2549,iEcSMS35_1347.EcSMS35_2569,iEcolC_1368.EcolC_1264,iG2583_1286.G2583_2946,iJO1366.b2414,iJR904.b2414,iLF82_1304.LF82_0418,iNRG857_1313.NRG857_12105,iSSON_1240.SSON_2503,iSbBS512_1146.SbBS512_E2766,iUMN146_1321.UM146_04550,iUMNK88_1353.UMNK88_3016,iUTI89_1310.UTI89_C2747,iWFL_1372.ECW_m2643,iY75_1357.Y75_RS12650,iZ_1308.Z3680	PALP
CMS1_k127_3601168_7	933262.AXAM01000014_gene284	1.979e-23	105.0	COG3584@1|root,COG3584@2|Bacteria,1NUBZ@1224|Proteobacteria,42ZKS@68525|delta/epsilon subdivisions,2WUSM@28221|Deltaproteobacteria,2MNAS@213118|Desulfobacterales	28221|Deltaproteobacteria	S	3D domain	-	-	-	-	-	-	-	-	-	-	-	-	3D
CMS1_k127_3601168_4	379066.GAU_0826	1.129e-76	264.0	COG1131@1|root,COG1131@2|Bacteria,1ZUPB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_3601168_3	886293.Sinac_6081	4.523e-89	315.0	28M0D@1|root,2ZAFE@2|Bacteria,2IX4T@203682|Planctomycetes	203682|Planctomycetes	S	Putative ATP-binding cassette	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran_2
CMS1_k127_3601168_6	635013.TherJR_1960	1.021e-46	171.0	COG0432@1|root,COG0432@2|Bacteria,1V6J7@1239|Firmicutes,24J8G@186801|Clostridia,2623P@186807|Peptococcaceae	186801|Clostridia	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
CMS1_k127_3601168_5	1288963.ADIS_4730	6.526e-68	239.0	COG0673@1|root,COG3733@1|root,COG0673@2|Bacteria,COG3733@2|Bacteria,4NN43@976|Bacteroidetes,47UBC@768503|Cytophagia	976|Bacteroidetes	Q	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_3609371_1	1288963.ADIS_1386	1.026e-96	342.0	28HHT@1|root,2Z7TE@2|Bacteria,4NIHS@976|Bacteroidetes,47MAA@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3609371_3	1267535.KB906767_gene4399	1.182e-74	284.0	COG2366@1|root,COG2366@2|Bacteria,3Y38M@57723|Acidobacteria	57723|Acidobacteria	S	Penicillin amidase	-	-	3.5.1.11,3.5.1.97	ko:K01434,ko:K07116	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
CMS1_k127_3609371_5	1298920.KI911353_gene2372	8.507e-06	58.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,21XPW@1506553|Lachnoclostridium	186801|Clostridia	KLT	PASTA	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
CMS1_k127_3609371_2	1125863.JAFN01000001_gene441	2.59e-86	293.0	COG1691@1|root,COG1691@2|Bacteria,1REQ7@1224|Proteobacteria,42MJG@68525|delta/epsilon subdivisions,2WN0G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
CMS1_k127_3609371_0	697281.Mahau_1643	6.396e-106	356.0	COG1641@1|root,COG1641@2|Bacteria,1TPAV@1239|Firmicutes,247ZH@186801|Clostridia,42FR9@68295|Thermoanaerobacterales	186801|Clostridia	S	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes	larC	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
CMS1_k127_3609371_4	404380.Gbem_1891	2.139e-21	94.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,42RJQ@68525|delta/epsilon subdivisions,2WNDS@28221|Deltaproteobacteria,43UMR@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
CMS1_k127_3609929_2	289376.THEYE_A0589	6.266e-48	189.0	COG0671@1|root,COG1807@1|root,COG0671@2|Bacteria,COG1807@2|Bacteria,3J155@40117|Nitrospirae	40117|Nitrospirae	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2,PMT_2
CMS1_k127_3609929_0	1236973.JCM9157_3548	1.69e-130	428.0	COG0673@1|root,COG0673@2|Bacteria,1TSWE@1239|Firmicutes,4HCQA@91061|Bacilli,1ZCI7@1386|Bacillus	91061|Bacilli	S	Oxidoreductase family, C-terminal alpha/beta domain	yrbE	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_3609929_1	351627.Csac_0390	6.908e-70	243.0	COG1082@1|root,COG1082@2|Bacteria,1TPJT@1239|Firmicutes,24A6G@186801|Clostridia,42FZ0@68295|Thermoanaerobacterales	186801|Clostridia	G	protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
CMS1_k127_3611281_0	1123242.JH636435_gene1524	1.08e-109	378.0	COG2936@1|root,COG2936@2|Bacteria,2J2G5@203682|Planctomycetes	203682|Planctomycetes	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
CMS1_k127_3615_2	880073.Calab_1896	2.141e-52	188.0	COG2173@1|root,COG2173@2|Bacteria,2NQ59@2323|unclassified Bacteria	2|Bacteria	M	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide	ddpX	-	3.2.1.52,3.4.13.22	ko:K01207,ko:K08641	ko00520,ko00531,ko01100,ko01501,ko01502,ko02020,map00520,map00531,map01100,map01501,map01502,map02020	M00628,M00651	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	Peptidase_M15
CMS1_k127_3615_3	575540.Isop_1414	1.555e-30	127.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	dsbE	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin,Thioredoxin_8
CMS1_k127_3615_0	338963.Pcar_1732	1.243e-152	487.0	COG0685@1|root,COG0685@2|Bacteria,1MUC9@1224|Proteobacteria,42P5X@68525|delta/epsilon subdivisions,2WIQW@28221|Deltaproteobacteria,43V2E@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
CMS1_k127_3615_1	1499967.BAYZ01000029_gene1223	3.544e-98	331.0	COG1530@1|root,COG1530@2|Bacteria,2NNQR@2323|unclassified Bacteria	2|Bacteria	J	Ribonuclease E/G family	rng	GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005856,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008996,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
CMS1_k127_3617195_0	1033743.CAES01000002_gene1850	3.339e-140	484.0	2DSG2@1|root,33G0F@2|Bacteria,1UMIX@1239|Firmicutes,4HW11@91061|Bacilli,26UN0@186822|Paenibacillaceae	91061|Bacilli	S	Heparinase II/III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III
CMS1_k127_3617195_1	344747.PM8797T_13695	1.717e-104	349.0	COG0179@1|root,COG0179@2|Bacteria,2IY8I@203682|Planctomycetes	203682|Planctomycetes	Q	2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
CMS1_k127_3617195_2	1120950.KB892816_gene7171	2.377e-05	55.0	29XIB@1|root,30J98@2|Bacteria,2H3UJ@201174|Actinobacteria	201174|Actinobacteria	S	Heparinase II/III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III
CMS1_k127_3619600_2	1173026.Glo7428_2690	1.649e-76	264.0	COG1028@1|root,COG1028@2|Bacteria,1G67A@1117|Cyanobacteria	1117|Cyanobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS1_k127_3619600_1	706587.Desti_2516	2.377e-87	296.0	COG0177@1|root,COG0177@2|Bacteria,1RAK3@1224|Proteobacteria,42M4V@68525|delta/epsilon subdivisions,2WPRX@28221|Deltaproteobacteria,2MQMZ@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	Protein of unknown function (DUF2400)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2400
CMS1_k127_3619600_0	269799.Gmet_3186	1.214e-90	302.0	COG0450@1|root,COG0450@2|Bacteria,1MWPY@1224|Proteobacteria,42MAJ@68525|delta/epsilon subdivisions,2WNT4@28221|Deltaproteobacteria,43T04@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	prx-2	-	1.11.1.15	ko:K03386,ko:K20011	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
CMS1_k127_3619600_3	237368.SCABRO_03961	3.915e-07	55.0	COG0392@1|root,COG0392@2|Bacteria,2J055@203682|Planctomycetes	203682|Planctomycetes	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
CMS1_k127_3620732_0	1089547.KB913013_gene980	2.67e-170	545.0	COG0673@1|root,COG0673@2|Bacteria,4NH96@976|Bacteroidetes,47M0H@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_3620732_1	471854.Dfer_4144	4.378e-67	234.0	COG0673@1|root,COG0673@2|Bacteria,4NH96@976|Bacteroidetes,47M0H@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_3633465_1	1423321.AS29_05870	0.0002986	51.0	COG0451@1|root,COG0451@2|Bacteria,1V04J@1239|Firmicutes	1239|Firmicutes	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3633465_0	686340.Metal_2868	1.013e-98	328.0	COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,1MU2Y@1224|Proteobacteria,1RN6C@1236|Gammaproteobacteria,1XEBW@135618|Methylococcales	135618|Methylococcales	EQ	Hydantoinase B/oxoprolinase	-	-	3.5.2.9	ko:K01469	ko00480,map00480	-	R00251	RC00553	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
CMS1_k127_3633626_10	941449.dsx2_0462	1.187e-08	57.0	COG1215@1|root,COG1215@2|Bacteria,1R988@1224|Proteobacteria,42QKI@68525|delta/epsilon subdivisions,2WM6J@28221|Deltaproteobacteria,2MG4E@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS1_k127_3633626_5	1267533.KB906741_gene530	4.672e-29	124.0	COG1595@1|root,COG1595@2|Bacteria,3Y4CH@57723|Acidobacteria,2JJ6R@204432|Acidobacteriia	204432|Acidobacteriia	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS1_k127_3633626_7	595536.ADVE02000001_gene3350	1.973e-24	104.0	2CT64@1|root,32SSN@2|Bacteria,1N7H4@1224|Proteobacteria,2UIPA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
CMS1_k127_3633626_6	562970.Btus_2694	7.667e-27	117.0	COG4226@1|root,COG4226@2|Bacteria,1VD64@1239|Firmicutes	1239|Firmicutes	S	HicB family	-	-	-	-	-	-	-	-	-	-	-	-	HicB
CMS1_k127_3633626_15	42565.FP66_03700	0.0003978	48.0	COG2801@1|root,COG2801@2|Bacteria,1MZ45@1224|Proteobacteria,1RSNX@1236|Gammaproteobacteria,1XPZB@135619|Oceanospirillales	135619|Oceanospirillales	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3633626_0	530564.Psta_3673	5.104e-148	488.0	COG2804@1|root,COG2804@2|Bacteria,2IYEE@203682|Planctomycetes	203682|Planctomycetes	NU	COG2804 Type II secretory pathway ATPase PulE Tfp pilus assembly pathway ATPase PilB	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
CMS1_k127_3633626_1	1304885.AUEY01000014_gene3352	5.567e-79	278.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42MH9@68525|delta/epsilon subdivisions,2WJE0@28221|Deltaproteobacteria,2MIYV@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	Type II secretion system (T2SS), protein F	-	-	-	ko:K02455	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
CMS1_k127_3633626_9	326297.Sama_0172	1.043e-17	92.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,1S3VS@1236|Gammaproteobacteria,2QBMZ@267890|Shewanellaceae	1236|Gammaproteobacteria	U	TIGRFAM general secretion pathway protein G	gspG	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
CMS1_k127_3633626_12	933262.AXAM01000042_gene1814	2.203e-07	60.0	COG4970@1|root,COG4970@2|Bacteria,1Q2B2@1224|Proteobacteria,43EWD@68525|delta/epsilon subdivisions,2X2AP@28221|Deltaproteobacteria,2MMAG@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
CMS1_k127_3633626_14	42256.RradSPS_0857	0.0001393	52.0	COG4966@1|root,COG4966@2|Bacteria	2|Bacteria	NU	pilus assembly protein PilW	-	-	-	ko:K02672	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	N_methyl,PilW
CMS1_k127_3633626_11	1123325.JHUV01000014_gene12	1.445e-07	63.0	COG3156@1|root,COG3156@2|Bacteria,2G4VW@200783|Aquificae	200783|Aquificae	U	Type II secretion system (T2SS), protein K	-	-	-	ko:K02460	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSK
CMS1_k127_3633626_13	1230338.MOMA_03515	8.348e-06	58.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,1RN8S@1236|Gammaproteobacteria,3NKVX@468|Moraxellaceae	1236|Gammaproteobacteria	NU	Type IV pilus assembly protein PilM;	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
CMS1_k127_3633626_4	247633.GP2143_02030	1.34e-33	151.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,1RPJS@1236|Gammaproteobacteria,1J4UY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	NU	general secretion pathway protein D	gspD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
CMS1_k127_3633626_2	251221.35213298	2.458e-49	181.0	COG0758@1|root,COG0758@2|Bacteria,1GACU@1117|Cyanobacteria	1117|Cyanobacteria	LU	Putative molybdenum carrier	-	-	-	-	-	-	-	-	-	-	-	-	MoCo_carrier
CMS1_k127_3633626_3	1128421.JAGA01000001_gene2006	1.629e-34	136.0	COG2363@1|root,COG2363@2|Bacteria,2NRMS@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function (DUF423)	ywdK	-	-	-	-	-	-	-	-	-	-	-	DUF423
CMS1_k127_3636912_22	1041146.ATZB01000010_gene4014	3.572e-07	63.0	COG1649@1|root,COG1649@2|Bacteria,1NP4V@1224|Proteobacteria,2UDGK@28211|Alphaproteobacteria,4B7UU@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Glycosyl hydrolase-like 10	-	-	-	-	-	-	-	-	-	-	-	-	GHL6,Glyco_hydro_42M
CMS1_k127_3636912_21	1267533.KB906734_gene3938	2.855e-07	60.0	COG2331@1|root,COG2331@2|Bacteria	2|Bacteria	P	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
CMS1_k127_3636912_6	63737.Npun_F4523	1.99e-98	332.0	COG1063@1|root,COG1063@2|Bacteria,1FZZE@1117|Cyanobacteria,1HJXK@1161|Nostocales	1117|Cyanobacteria	E	PFAM Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N,Shikimate_DH
CMS1_k127_3636912_9	1303518.CCALI_00279	9.399e-77	267.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
CMS1_k127_3636912_15	240016.ABIZ01000001_gene272	8.663e-34	141.0	COG0859@1|root,COG0859@2|Bacteria,46SZK@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
CMS1_k127_3636912_8	1232453.BAIF02000055_gene1218	8.354e-87	298.0	COG1082@1|root,COG1082@2|Bacteria,1V81Y@1239|Firmicutes,24NI1@186801|Clostridia	186801|Clostridia	G	Xylose isomerase-like TIM barrel	-	-	5.1.3.38	ko:K21909	-	-	-	-	ko00000,ko01000	-	-	-	AP_endonuc_2
CMS1_k127_3636912_14	1501230.ET33_10715	5.549e-50	189.0	COG1136@1|root,COG1136@2|Bacteria,1TR90@1239|Firmicutes,4HDK0@91061|Bacilli,26UI1@186822|Paenibacillaceae	91061|Bacilli	V	ATP-binding protein	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_3636912_10	517418.Ctha_2415	2.561e-73	263.0	COG0577@1|root,COG0577@2|Bacteria,1FEN8@1090|Chlorobi	1090|Chlorobi	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS1_k127_3636912_19	1123508.JH636443_gene5124	2.074e-11	73.0	COG3495@1|root,COG3495@2|Bacteria,2J2P9@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF3299)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3299
CMS1_k127_3636912_16	278957.ABEA03000099_gene817	3.56e-32	134.0	COG1385@1|root,COG1385@2|Bacteria,46SZQ@74201|Verrucomicrobia,3K7Y0@414999|Opitutae	414999|Opitutae	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	-	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
CMS1_k127_3636912_7	324602.Caur_2858	2.354e-93	332.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PKD,SBBP
CMS1_k127_3636912_23	1159870.KB907784_gene741	9.855e-06	57.0	COG0697@1|root,COG0697@2|Bacteria,1MZQM@1224|Proteobacteria,2VI5H@28216|Betaproteobacteria	28216|Betaproteobacteria	EG	Drug metabolite transporter (DMT) superfamily	yijE_1	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS1_k127_3636912_3	314230.DSM3645_14945	4.875e-160	516.0	COG0673@1|root,COG0673@2|Bacteria,2IXUF@203682|Planctomycetes	2|Bacteria	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_3636912_20	383372.Rcas_4129	3.473e-08	65.0	COG0823@1|root,COG0823@2|Bacteria,2G8PZ@200795|Chloroflexi,377MH@32061|Chloroflexia	32061|Chloroflexia	U	WD40 domain protein beta Propeller	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
CMS1_k127_3636912_17	1254432.SCE1572_06790	1.968e-17	91.0	290ZT@1|root,2ZNMH@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3636912_4	59374.Fisuc_2717	3.037e-145	473.0	COG1696@1|root,COG1696@2|Bacteria	2|Bacteria	M	negative regulation of protein lipidation	algI	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
CMS1_k127_3636912_12	59374.Fisuc_2588	1.715e-58	217.0	2C7PP@1|root,33K9Q@2|Bacteria	2|Bacteria	S	SGNH hydrolase-like domain, acetyltransferase AlgX	-	-	-	ko:K19295	-	-	-	-	ko00000	-	-	-	ALGX
CMS1_k127_3636912_0	700598.Niako_0565	1.095e-217	703.0	COG0591@1|root,COG3055@1|root,COG0591@2|Bacteria,COG3055@2|Bacteria,4NEN8@976|Bacteroidetes,1J18W@117747|Sphingobacteriia	976|Bacteroidetes	E	COGs COG0591 Na proline symporter	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	Kelch_1,Kelch_5,Kelch_6,SSF
CMS1_k127_3636912_13	1449063.JMLS01000024_gene3690	1.981e-58	216.0	COG0329@1|root,COG0329@2|Bacteria,1V10S@1239|Firmicutes,4HGKS@91061|Bacilli,26R9X@186822|Paenibacillaceae	91061|Bacilli	EM	Dihydrodipicolinate synthetase family	-	-	4.1.2.28,4.3.3.7	ko:K01714,ko:K22397	ko00040,ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00040,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R01782,R10147	RC00307,RC00572,RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
CMS1_k127_3636912_11	1403819.BATR01000018_gene572	1.414e-68	241.0	COG1028@1|root,COG1028@2|Bacteria,46UUI@74201|Verrucomicrobia	74201|Verrucomicrobia	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS1_k127_3636912_24	344747.PM8797T_19385	0.0002346	54.0	COG3291@1|root,COG3291@2|Bacteria,2J3CN@203682|Planctomycetes	203682|Planctomycetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3636912_1	344747.PM8797T_04335	2.339e-179	575.0	COG3119@1|root,COG3119@2|Bacteria,2J2Z5@203682|Planctomycetes	203682|Planctomycetes	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
CMS1_k127_3636912_5	452637.Oter_0961	3.828e-138	453.0	COG1171@1|root,COG1171@2|Bacteria,46TW9@74201|Verrucomicrobia,3K73X@414999|Opitutae	414999|Opitutae	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
CMS1_k127_3636912_2	641524.ADICYQ_5476	5.338e-172	561.0	COG1053@1|root,COG1053@2|Bacteria,4NG56@976|Bacteroidetes,47YCZ@768503|Cytophagia	976|Bacteroidetes	C	HI0933-like protein	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
CMS1_k127_3636912_18	926569.ANT_06890	9.939e-13	70.0	2ECEX@1|root,336D4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3642906_0	935866.JAER01000035_gene3227	1.414e-08	63.0	2BMJ0@1|root,32G3X@2|Bacteria,2I09M@201174|Actinobacteria,4DWDV@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3642906_1	44056.XP_009040687.1	1.463e-05	57.0	2E7AH@1|root,2SDXA@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Chlam_PMP
CMS1_k127_3645923_3	926550.CLDAP_17270	6.672e-81	276.0	COG0673@1|root,COG0673@2|Bacteria,2G7X7@200795|Chloroflexi	200795|Chloroflexi	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_3645923_5	395961.Cyan7425_2119	2.021e-44	167.0	COG1051@1|root,COG1051@2|Bacteria,1FZVE@1117|Cyanobacteria,3KGUD@43988|Cyanothece	1117|Cyanobacteria	F	PFAM NUDIX hydrolase	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
CMS1_k127_3645923_4	1304875.JAFZ01000001_gene1554	6.725e-53	193.0	COG1335@1|root,COG1335@2|Bacteria,3TAXX@508458|Synergistetes	508458|Synergistetes	Q	Isochorismatase family	-	-	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
CMS1_k127_3645923_0	642492.Clole_3641	2.674e-143	471.0	COG1488@1|root,COG1488@2|Bacteria,1TPDW@1239|Firmicutes,247NY@186801|Clostridia	186801|Clostridia	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase,QRPTase_C,QRPTase_N
CMS1_k127_3645923_1	1278073.MYSTI_07441	1.177e-123	420.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,42N86@68525|delta/epsilon subdivisions,2WIV4@28221|Deltaproteobacteria,2YTUK@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
CMS1_k127_3645923_2	880073.Calab_0773	5.782e-91	306.0	COG0449@1|root,COG0449@2|Bacteria,2NNWC@2323|unclassified Bacteria	2|Bacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iAF987.Gmet_1487	GATase_6,SIS
CMS1_k127_3649281_0	192952.MM_2478	3.983e-47	193.0	COG2304@1|root,arCOG04500@1|root,arCOG02902@2157|Archaea,arCOG04500@2157|Archaea,2XVVH@28890|Euryarchaeota	28890|Euryarchaeota	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
CMS1_k127_3649281_1	1121403.AUCV01000020_gene3093	2.138e-09	71.0	COG2755@1|root,COG4886@1|root,COG2755@2|Bacteria,COG4886@2|Bacteria,1RHDZ@1224|Proteobacteria,42SMX@68525|delta/epsilon subdivisions,2WPRJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS1_k127_3655985_9	639030.JHVA01000001_gene3028	1.383e-23	102.0	COG1592@1|root,COG1592@2|Bacteria,3Y5YA@57723|Acidobacteria,2JK5H@204432|Acidobacteriia	204432|Acidobacteriia	C	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
CMS1_k127_3655985_5	1123508.JH636449_gene7420	9.973e-70	250.0	COG2202@1|root,COG4191@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,COG4251@2|Bacteria,2IZ70@203682|Planctomycetes	203682|Planctomycetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9
CMS1_k127_3655985_6	1120971.AUCA01000006_gene2062	2.484e-53	196.0	COG0745@1|root,COG0745@2|Bacteria,1UZB6@1239|Firmicutes,4HBUW@91061|Bacilli,279DX@186823|Alicyclobacillaceae	91061|Bacilli	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_3655985_0	671143.DAMO_2996	2.574e-142	477.0	COG1032@1|root,COG1032@2|Bacteria,2NQU0@2323|unclassified Bacteria	2|Bacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
CMS1_k127_3655985_8	1144319.PMI16_05022	6.951e-30	124.0	COG0745@1|root,COG0745@2|Bacteria,1RD6H@1224|Proteobacteria,2VRA0@28216|Betaproteobacteria,474YR@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS1_k127_3655985_18	1131451.O1K_11870	0.0001109	46.0	COG5510@1|root,COG5510@2|Bacteria	2|Bacteria	S	response to toxic substance	ecnA	-	-	ko:K16348	-	-	-	-	ko00000,ko02000	9.B.13.1.1	-	-	Entericidin
CMS1_k127_3655985_1	886293.Sinac_1118	3.298e-123	413.0	COG3064@1|root,COG3064@2|Bacteria,2IXYB@203682|Planctomycetes	203682|Planctomycetes	M	YXWGXW repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	YXWGXW
CMS1_k127_3655985_12	909663.KI867150_gene2309	8.506e-14	77.0	COG4447@1|root,COG4447@2|Bacteria,1PFB5@1224|Proteobacteria,437G8@68525|delta/epsilon subdivisions,2X2NT@28221|Deltaproteobacteria,2MRPS@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3655985_13	443143.GM18_2737	4.358e-13	72.0	2EFZF@1|root,339RM@2|Bacteria,1NH6S@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3655985_10	1123228.AUIH01000039_gene2893	2.626e-20	92.0	2DNSI@1|root,32YXC@2|Bacteria,1N7K2@1224|Proteobacteria,1SD17@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3655985_11	316057.RPD_1374	1.437e-15	80.0	COG3237@1|root,COG3237@2|Bacteria,1N6X4@1224|Proteobacteria,2UF5Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Belongs to the UPF0337 (CsbD) family	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
CMS1_k127_3655985_14	1116369.KB890024_gene2402	5.561e-13	73.0	COG3360@1|root,COG3360@2|Bacteria,1N6YT@1224|Proteobacteria,2UKPX@28211|Alphaproteobacteria,43QUB@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
CMS1_k127_3655985_16	452637.Oter_0299	4.089e-05	51.0	COG1595@1|root,COG1595@2|Bacteria,46VX9@74201|Verrucomicrobia	74201|Verrucomicrobia	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_3655985_4	941824.TCEL_00588	9.226e-89	314.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia,36DCW@31979|Clostridiaceae	186801|Clostridia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsP	-	2.7.3.9,2.7.9.2	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
CMS1_k127_3655985_2	373903.Hore_13580	5.547e-101	346.0	COG1032@1|root,COG1032@2|Bacteria,1TPGT@1239|Firmicutes,247JS@186801|Clostridia,3WC51@53433|Halanaerobiales	186801|Clostridia	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4080,Radical_SAM
CMS1_k127_3655985_7	317936.Nos7107_1078	1.698e-44	171.0	COG1357@1|root,COG1357@2|Bacteria,1G1UU@1117|Cyanobacteria,1HJXN@1161|Nostocales	1117|Cyanobacteria	S	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
CMS1_k127_3655985_3	338966.Ppro_1017	9.585e-95	325.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	Phage_int_SAM_3,Phage_integrase
CMS1_k127_365791_2	595460.RRSWK_04461	1.726e-105	357.0	COG0673@1|root,COG0673@2|Bacteria,2IXRR@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_365791_0	945713.IALB_2034	7.764e-154	503.0	COG0733@1|root,COG0733@2|Bacteria	2|Bacteria	S	neurotransmitter:sodium symporter activity	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
CMS1_k127_365791_1	1403819.BATR01000168_gene5776	7.048e-127	418.0	COG0823@1|root,COG0823@2|Bacteria,46SJJ@74201|Verrucomicrobia	74201|Verrucomicrobia	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_365791_3	68570.DC74_6120	2.714e-08	61.0	COG0584@1|root,COG3534@1|root,COG0584@2|Bacteria,COG3534@2|Bacteria,2GNM5@201174|Actinobacteria	201174|Actinobacteria	C	glycerophosphoryl diester phosphodiesterase	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD,Laminin_G_3
CMS1_k127_3661812_0	477974.Daud_0865	1.911e-219	697.0	COG0438@1|root,COG1331@1|root,COG0438@2|Bacteria,COG1331@2|Bacteria,1TQRQ@1239|Firmicutes,249H2@186801|Clostridia,2607T@186807|Peptococcaceae	186801|Clostridia	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS1_k127_3663453_1	1297742.A176_07216	4.037e-27	119.0	COG1225@1|root,COG1225@2|Bacteria,1RD2X@1224|Proteobacteria,430VE@68525|delta/epsilon subdivisions,2WVX8@28221|Deltaproteobacteria,2YVEC@29|Myxococcales	28221|Deltaproteobacteria	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
CMS1_k127_3663453_3	1336803.PHEL49_1670	1.489e-15	86.0	COG0526@1|root,COG0526@2|Bacteria,4NQ9U@976|Bacteroidetes,1I2Z8@117743|Flavobacteriia,3VWHG@52959|Polaribacter	976|Bacteroidetes	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Thioredoxin
CMS1_k127_3663453_2	1304885.AUEY01000032_gene2018	2.335e-17	88.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2MIB8@213118|Desulfobacterales	28221|Deltaproteobacteria	T	response regulator receiver	-	-	-	ko:K02481,ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS1_k127_3663453_0	290512.Paes_1002	4.453e-68	250.0	COG1301@1|root,COG1301@2|Bacteria,1FD7Z@1090|Chlorobi	1090|Chlorobi	U	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
CMS1_k127_3663453_4	1449063.JMLS01000014_gene1559	0.0001353	49.0	COG3595@1|root,COG3595@2|Bacteria,1V5K9@1239|Firmicutes,4HEU4@91061|Bacilli,26URZ@186822|Paenibacillaceae	91061|Bacilli	S	Putative adhesin	liaG1	-	-	-	-	-	-	-	-	-	-	-	DUF4097
CMS1_k127_3663806_5	575540.Isop_2516	1.855e-13	72.0	COG4102@1|root,COG4102@2|Bacteria,2IXN7@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CMS1_k127_3663806_3	1303518.CCALI_01048	4.319e-75	264.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
CMS1_k127_3663806_4	1405498.SSIM_05750	1.627e-23	106.0	COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,4H9KR@91061|Bacilli,4GXVJ@90964|Staphylococcaceae	91061|Bacilli	G	PTS system, fructose-specific	fruA	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
CMS1_k127_3663806_0	344747.PM8797T_20763	4.278e-149	488.0	COG1331@1|root,COG1331@2|Bacteria,2IXCB@203682|Planctomycetes	203682|Planctomycetes	O	Pectic acid lyase	-	-	-	-	-	-	-	-	-	-	-	-	Pec_lyase
CMS1_k127_3663806_1	521674.Plim_3510	1.198e-96	331.0	COG0673@1|root,COG0673@2|Bacteria,2IXRR@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_3663806_2	324057.Pjdr2_3567	6.807e-83	286.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,VCBS
CMS1_k127_3664789_0	926569.ANT_15490	1.065e-97	323.0	COG1217@1|root,COG1217@2|Bacteria,2G5NQ@200795|Chloroflexi	200795|Chloroflexi	T	elongation factor Tu domain 2 protein	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
CMS1_k127_3664789_2	1521187.JPIM01000010_gene2121	0.0002915	49.0	COG1716@1|root,COG3391@1|root,COG4733@1|root,COG1716@2|Bacteria,COG3391@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	2.7.11.1,3.2.1.78	ko:K01218,ko:K12132	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000,ko01001	-	GH26	-	FHA,NHL,fn3
CMS1_k127_3664789_1	1157490.EL26_09010	5.613e-67	235.0	COG1853@1|root,COG1853@2|Bacteria,1V52S@1239|Firmicutes,4HGD9@91061|Bacilli,279PY@186823|Alicyclobacillaceae	91061|Bacilli	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
CMS1_k127_3677997_5	1121441.AUCX01000004_gene3071	5.819e-11	76.0	COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,42MJ8@68525|delta/epsilon subdivisions,2WJF3@28221|Deltaproteobacteria,2M98U@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM alpha-2-macroglobulin domain protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,MG1,Thiol-ester_cl
CMS1_k127_3677997_6	1499967.BAYZ01000105_gene3516	1.709e-10	68.0	COG2260@1|root,COG2260@2|Bacteria	2|Bacteria	J	snoRNA binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF2007
CMS1_k127_3677997_0	368408.Tpen_1559	7.694e-149	487.0	COG2407@1|root,arCOG01772@2157|Archaea	2157|Archaea	G	L-fucose isomerase and related	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3677997_8	756272.Plabr_1230	2.731e-06	59.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CMS1_k127_3677997_3	1396141.BATP01000020_gene90	3.093e-31	126.0	COG1695@1|root,COG1695@2|Bacteria,46WGD@74201|Verrucomicrobia,2IW9N@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
CMS1_k127_3677997_4	1408224.SAMCCGM7_c0266	1.041e-18	94.0	COG3932@1|root,COG3932@2|Bacteria,1REE4@1224|Proteobacteria,2U7Z2@28211|Alphaproteobacteria,4BBJD@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	ABC-type transport system, permease components	exoD	-	-	-	-	-	-	-	-	-	-	-	ExoD
CMS1_k127_3677997_2	1254432.SCE1572_39205	1.763e-88	299.0	COG3228@1|root,COG3228@2|Bacteria,1RAHF@1224|Proteobacteria,42QKQ@68525|delta/epsilon subdivisions,2WUIA@28221|Deltaproteobacteria,2YV7F@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the MtfA family	-	-	-	ko:K09933	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_M90
CMS1_k127_3677997_1	383372.Rcas_3216	3.344e-100	331.0	COG0667@1|root,COG0667@2|Bacteria,2G6AM@200795|Chloroflexi	200795|Chloroflexi	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS1_k127_3686930_0	1122917.KB899679_gene454	2.255e-58	212.0	COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,4HA4R@91061|Bacilli,26QVV@186822|Paenibacillaceae	91061|Bacilli	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
CMS1_k127_3686930_1	118168.MC7420_7199	2.121e-29	130.0	COG1716@1|root,COG2114@1|root,COG2203@1|root,COG1716@2|Bacteria,COG2114@2|Bacteria,COG2203@2|Bacteria,1G1FY@1117|Cyanobacteria,1H99S@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,GAF,Guanylate_cyc,Yop-YscD_cpl
CMS1_k127_3687245_4	330214.NIDE1358	5.235e-46	168.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,3J0EB@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
CMS1_k127_3687245_5	204669.Acid345_4447	7.249e-38	159.0	COG2067@1|root,COG2067@2|Bacteria,3Y3JJ@57723|Acidobacteria,2JJB9@204432|Acidobacteriia	204432|Acidobacteriia	I	Putative beta-barrel porin-2, OmpL-like. bbp2	-	-	-	-	-	-	-	-	-	-	-	-	BBP2
CMS1_k127_3687245_1	671143.DAMO_1683	2.783e-194	616.0	COG0004@1|root,COG0004@2|Bacteria,2NQS8@2323|unclassified Bacteria	2|Bacteria	P	Ammonium Transporter Family	amt	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	iHN637.CLJU_c42670,iYO844.BSU36510	Ammonium_transp
CMS1_k127_3687245_0	330214.NIDE1360	4.248e-198	626.0	COG0004@1|root,COG0004@2|Bacteria,3J0IS@40117|Nitrospirae	40117|Nitrospirae	P	Ammonium Transporter Family	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
CMS1_k127_3687245_3	330214.NIDE1361	3.514e-57	200.0	COG0347@1|root,COG0347@2|Bacteria,3J0P1@40117|Nitrospirae	40117|Nitrospirae	K	Nitrogen regulatory protein P-II	-	-	-	ko:K04751,ko:K04752	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
CMS1_k127_3687245_2	330214.NIDE1362	2.098e-178	568.0	COG2844@1|root,COG2844@2|Bacteria	2|Bacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.42,2.7.7.59,2.7.7.89	ko:K00982,ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,GlnD_UR_UTase,HD,NTP_transf_2
CMS1_k127_3694884_0	556261.HMPREF0240_03412	1.861e-07	65.0	COG0612@1|root,COG0612@2|Bacteria	2|Bacteria	L	Peptidase, M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	CBM_35,Glyco_hydro_98C,Glyco_hydro_98M,Peptidase_M16_C,Relaxase
CMS1_k127_3694884_1	765913.ThidrDRAFT_2198	3.246e-06	57.0	COG3292@1|root,COG3292@2|Bacteria,1NBC9@1224|Proteobacteria,1T5A4@1236|Gammaproteobacteria,1X05H@135613|Chromatiales	135613|Chromatiales	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3714506_0	1278307.KB906968_gene2130	1.462e-51	192.0	2EMTG@1|root,33FFU@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
CMS1_k127_3714506_3	1382305.AZUC01000047_gene774	1.154e-05	57.0	COG0457@1|root,COG0457@2|Bacteria,1V1HX@1239|Firmicutes,4HG5V@91061|Bacilli,26DTC@186818|Planococcaceae	91061|Bacilli	S	Tetratricopeptide repeat	yrrB	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_6,TPR_8
CMS1_k127_3714506_2	1304275.C41B8_10128	3.855e-23	104.0	COG4103@1|root,COG4103@2|Bacteria,1N6YZ@1224|Proteobacteria,1SD1K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TerB
CMS1_k127_3714506_1	335543.Sfum_2529	2.002e-32	133.0	COG1514@1|root,COG1514@2|Bacteria,1RDB2@1224|Proteobacteria,42TMM@68525|delta/epsilon subdivisions,2WQ6S@28221|Deltaproteobacteria,2MRXS@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
CMS1_k127_3724346_6	1278073.MYSTI_03970	4.468e-38	143.0	COG1051@1|root,COG1051@2|Bacteria,1NGJE@1224|Proteobacteria,42ZGV@68525|delta/epsilon subdivisions,2WUZ3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	NUDIX domain	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
CMS1_k127_3724346_3	1340493.JNIF01000003_gene2335	7.221e-63	226.0	COG1082@1|root,COG1082@2|Bacteria,3Y7IK@57723|Acidobacteria	57723|Acidobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS1_k127_3724346_2	886293.Sinac_2964	9.847e-66	237.0	COG3622@1|root,COG3622@2|Bacteria,2J4Z5@203682|Planctomycetes	203682|Planctomycetes	G	PFAM Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS1_k127_3724346_0	1123242.JH636434_gene4078	1.62e-115	381.0	COG0500@1|root,COG2226@2|Bacteria,2IXEP@203682|Planctomycetes	203682|Planctomycetes	Q	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
CMS1_k127_3724346_5	1460634.JCM19037_968	1.411e-40	159.0	COG0300@1|root,COG0300@2|Bacteria,1UG37@1239|Firmicutes,4HC7Y@91061|Bacilli	91061|Bacilli	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
CMS1_k127_3724346_1	452637.Oter_2892	2.176e-81	284.0	COG1335@1|root,COG1335@2|Bacteria	2|Bacteria	Q	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	-	-	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase,MDMPI_N
CMS1_k127_3724346_7	1385510.N781_09540	2.624e-35	157.0	COG2373@1|root,COG4932@1|root,COG2373@2|Bacteria,COG4932@2|Bacteria,1UXD9@1239|Firmicutes,4I2J1@91061|Bacilli,2YBSI@289201|Pontibacillus	91061|Bacilli	M	SdrD B-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3724346_4	867903.ThesuDRAFT_01483	2.92e-61	217.0	COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,248Y5@186801|Clostridia,3WD5B@538999|Clostridiales incertae sedis	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
CMS1_k127_3724346_8	1444712.BN1013_00179	4.854e-32	135.0	COG1197@1|root,COG1197@2|Bacteria,2JFGI@204428|Chlamydiae	204428|Chlamydiae	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
CMS1_k127_3725391_1	926692.AZYG01000085_gene833	2.051e-63	219.0	COG0415@1|root,COG0415@2|Bacteria,1UDZT@1239|Firmicutes,249FJ@186801|Clostridia,3WAHJ@53433|Halanaerobiales	186801|Clostridia	L	PFAM DNA photolyase	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase
CMS1_k127_3725391_0	1304872.JAGC01000009_gene1138	2.2e-85	292.0	COG1090@1|root,COG1090@2|Bacteria,1MUB4@1224|Proteobacteria,42QUU@68525|delta/epsilon subdivisions,2WKRY@28221|Deltaproteobacteria,2M9EG@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	NAD-dependent epimerase dehydratase	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
CMS1_k127_3725391_3	335543.Sfum_1116	3.039e-29	121.0	COG0748@1|root,COG0748@2|Bacteria,1N2JV@1224|Proteobacteria,42TYW@68525|delta/epsilon subdivisions,2WQEM@28221|Deltaproteobacteria,2MQHZ@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
CMS1_k127_3725391_2	1125863.JAFN01000001_gene2299	5.196e-49	182.0	COG2344@1|root,COG2344@2|Bacteria,1R55V@1224|Proteobacteria,42M2S@68525|delta/epsilon subdivisions,2WM6N@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
CMS1_k127_3727940_1	502025.Hoch_2148	2.565e-62	225.0	COG1597@1|root,COG1597@2|Bacteria,1RCJT@1224|Proteobacteria,42W6W@68525|delta/epsilon subdivisions,2X6V3@28221|Deltaproteobacteria,2YUYD@29|Myxococcales	28221|Deltaproteobacteria	I	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
CMS1_k127_3727940_0	880073.Calab_2578	1.332e-104	357.0	COG4284@1|root,COG4284@2|Bacteria	2|Bacteria	G	Utp--glucose-1-phosphate uridylyltransferase	CP_1013	-	2.7.7.23,2.7.7.83	ko:K00972,ko:K11442	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00361,M00362	R00416	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPGP
CMS1_k127_3732309_5	313628.LNTAR_15902	2.685e-71	247.0	COG0118@1|root,COG0118@2|Bacteria	2|Bacteria	E	glutamine metabolic process	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
CMS1_k127_3732309_6	357808.RoseRS_0238	9.183e-43	160.0	COG0614@1|root,COG0614@2|Bacteria,2G9KR@200795|Chloroflexi,377CA@32061|Chloroflexia	32061|Chloroflexia	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
CMS1_k127_3732309_4	247490.KSU1_D0951	3.809e-74	261.0	COG1940@1|root,COG1940@2|Bacteria,2IYBR@203682|Planctomycetes	203682|Planctomycetes	GK	transcriptional regulator sugar kinase	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
CMS1_k127_3732309_1	562970.Btus_0613	2.094e-120	404.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,4HBS0@91061|Bacilli,279F0@186823|Alicyclobacillaceae	91061|Bacilli	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	-	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
CMS1_k127_3732309_0	1125863.JAFN01000001_gene1578	2.406e-270	841.0	COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,42MAX@68525|delta/epsilon subdivisions,2WJ5B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	PFAM Glutamyl glutaminyl-tRNA synthetase, class Ic, catalytic	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	GatB_Yqey,tRNA-synt_1c,tRNA-synt_1c_C
CMS1_k127_3732309_7	1089553.Tph_c26700	8.806e-41	154.0	COG0853@1|root,COG0853@2|Bacteria,1V6NQ@1239|Firmicutes,24JVN@186801|Clostridia,42GKF@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
CMS1_k127_3732309_3	1219084.AP014508_gene201	1.198e-87	302.0	COG0414@1|root,COG0414@2|Bacteria,2GC24@200918|Thermotogae	200918|Thermotogae	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
CMS1_k127_3732309_2	580327.Tthe_2222	5.566e-92	310.0	COG0413@1|root,COG0413@2|Bacteria,1TPZA@1239|Firmicutes,248RR@186801|Clostridia,42FEE@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
CMS1_k127_3732309_8	1235755.ANAM01000010_gene2022	2.672e-40	154.0	COG0801@1|root,COG0801@2|Bacteria,1V6PR@1239|Firmicutes,4HIMG@91061|Bacilli,4GYZA@90964|Staphylococcaceae	91061|Bacilli	H	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
CMS1_k127_3734828_3	344747.PM8797T_08374	8.497e-15	88.0	COG1621@1|root,COG1621@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 32 family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,HTH_18
CMS1_k127_3734828_1	1121423.JONT01000009_gene1429	1.309e-170	559.0	COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,247T0@186801|Clostridia,260I6@186807|Peptococcaceae	186801|Clostridia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
CMS1_k127_3734828_2	880073.Calab_1196	2.568e-163	552.0	COG0841@1|root,COG0841@2|Bacteria,2NNUH@2323|unclassified Bacteria	2|Bacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
CMS1_k127_3734828_0	945713.IALB_2739	1.629e-214	674.0	COG0114@1|root,COG0114@2|Bacteria	2|Bacteria	C	fumarate hydratase activity	fumC	GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
CMS1_k127_3737733_0	313628.LNTAR_23674	4.034e-122	406.0	COG3344@1|root,COG3344@2|Bacteria	2|Bacteria	L	reverse transcriptase	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,RVT_1
CMS1_k127_3737733_1	497964.CfE428DRAFT_6245	1.058e-07	56.0	COG0515@1|root,COG0515@2|Bacteria,46U28@74201|Verrucomicrobia	74201|Verrucomicrobia	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS1_k127_3738420_1	1173028.ANKO01000112_gene4787	3.045e-117	389.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1GBMT@1117|Cyanobacteria,1HE9H@1150|Oscillatoriales	1117|Cyanobacteria	GT	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
CMS1_k127_3738420_2	1173028.ANKO01000112_gene4788	1.409e-98	331.0	COG0382@1|root,COG0382@2|Bacteria,1GBH5@1117|Cyanobacteria,1HE6Y@1150|Oscillatoriales	1117|Cyanobacteria	H	UbiA prenyltransferase family	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
CMS1_k127_3738420_0	756272.Plabr_2744	8.384e-123	400.0	COG3119@1|root,COG3119@2|Bacteria,2IYNZ@203682|Planctomycetes	203682|Planctomycetes	P	arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS1_k127_376609_1	926550.CLDAP_07110	1.927e-104	349.0	COG0457@1|root,COG0457@2|Bacteria,2G76G@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF4037)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4037
CMS1_k127_376609_2	382464.ABSI01000010_gene3515	7.052e-40	168.0	2F006@1|root,33T46@2|Bacteria,46U4Y@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_376609_0	1047013.AQSP01000126_gene2738	1.375e-185	592.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,HEAT_2
CMS1_k127_3766625_28	883126.HMPREF9710_04265	0.0009359	48.0	COG2885@1|root,COG2885@2|Bacteria,1MWHF@1224|Proteobacteria,2VIJS@28216|Betaproteobacteria,473QS@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Belongs to the ompA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	BON,OmpA
CMS1_k127_3766625_17	748280.NH8B_2378	3.089e-42	166.0	COG2064@1|root,COG2064@2|Bacteria,1MWAZ@1224|Proteobacteria,2VIA4@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	Type II secretion system	tadC	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
CMS1_k127_3766625_19	290340.AAur_2913	1.793e-23	111.0	COG4965@1|root,COG4965@2|Bacteria,2H577@201174|Actinobacteria	201174|Actinobacteria	U	Type ii secretion system	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF,VWA_2
CMS1_k127_3766625_1	1210884.HG799465_gene12229	2.463e-152	495.0	COG4962@1|root,COG4962@2|Bacteria,2IXAQ@203682|Planctomycetes	203682|Planctomycetes	U	Secretion system protein	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
CMS1_k127_3766625_20	314270.RB2083_4100	2.518e-23	113.0	COG4963@1|root,COG4963@2|Bacteria,1MWNY@1224|Proteobacteria,2TUDS@28211|Alphaproteobacteria,3ZH3X@58840|unclassified Rhodobacteraceae	28211|Alphaproteobacteria	U	AAA domain	minD	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31
CMS1_k127_3766625_12	330214.NIDE2116	1.099e-80	290.0	COG4964@1|root,COG4964@2|Bacteria	2|Bacteria	U	Pilus formation protein N terminal region	cpaC	-	-	ko:K02280	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	BON,Secretin,T2SS-T3SS_pil_N
CMS1_k127_3766625_22	744980.TRICHSKD4_1781	9.911e-15	85.0	COG3745@1|root,COG3745@2|Bacteria,1MW75@1224|Proteobacteria,2TTPE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	Pilus assembly protein CpaB	cpaB	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	RcpC,SAF
CMS1_k127_3766625_23	314230.DSM3645_06434	1.113e-13	78.0	COG4961@1|root,COG4961@2|Bacteria,2J0PV@203682|Planctomycetes	203682|Planctomycetes	U	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
CMS1_k127_3766625_26	1121459.AQXE01000020_gene770	1.727e-10	71.0	COG1989@1|root,COG1989@2|Bacteria,1R34X@1224|Proteobacteria,42V6M@68525|delta/epsilon subdivisions,2WRP6@28221|Deltaproteobacteria,2MCVZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	NOU	PFAM Peptidase A24A, prepilin type IV	-	-	3.4.23.43	ko:K02278	-	-	-	-	ko00000,ko01000,ko02035,ko02044	-	-	-	Peptidase_A24
CMS1_k127_3766625_29	404589.Anae109_3972	0.0009684	46.0	COG3847@1|root,COG3847@2|Bacteria,1NGVU@1224|Proteobacteria,42X6U@68525|delta/epsilon subdivisions,2WSP7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	PFAM Flp Fap pilin component	-	-	-	ko:K02651	ko04112,map04112	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	Flp_Fap
CMS1_k127_3766625_5	886293.Sinac_2421	2.602e-106	354.0	COG0673@1|root,COG0673@2|Bacteria,2IWZY@203682|Planctomycetes	203682|Planctomycetes	G	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_3766625_13	234267.Acid_6247	1.734e-75	271.0	COG0673@1|root,COG0673@2|Bacteria,3Y39X@57723|Acidobacteria	57723|Acidobacteria	S	PFAM oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_3766625_2	509635.N824_15295	3.81e-147	487.0	2DBGI@1|root,2Z94U@2|Bacteria,4NI4P@976|Bacteroidetes,1IVFE@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3766625_8	234267.Acid_7682	1.328e-90	311.0	COG2133@1|root,COG2133@2|Bacteria,3Y6W0@57723|Acidobacteria	57723|Acidobacteria	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,VCBS
CMS1_k127_3766625_4	1122939.ATUD01000001_gene577	7.694e-137	469.0	COG1520@1|root,COG1520@2|Bacteria,2H3K4@201174|Actinobacteria,4CRJK@84995|Rubrobacteria	84995|Rubrobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3766625_16	266117.Rxyl_2282	1.615e-47	195.0	COG0515@1|root,COG0515@2|Bacteria,2GMPZ@201174|Actinobacteria,4CU1S@84995|Rubrobacteria	201174|Actinobacteria	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS1_k127_3766625_7	595460.RRSWK_05578	2.154e-93	330.0	COG2204@1|root,COG2204@2|Bacteria,2IYSJ@203682|Planctomycetes	203682|Planctomycetes	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HTH_8,Sigma54_activat,Yop-YscD_cpl
CMS1_k127_3766625_10	331113.SNE_A09210	1.916e-86	304.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,2JHEU@204428|Chlamydiae	204428|Chlamydiae	H	ThiF family	-	-	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
CMS1_k127_3766625_6	1122915.AUGY01000014_gene2769	7.308e-105	351.0	COG4447@1|root,COG4447@2|Bacteria,1UU3Y@1239|Firmicutes,4HCEG@91061|Bacilli	91061|Bacilli	S	cellulose binding	hcf136	-	-	-	-	-	-	-	-	-	-	-	BNR
CMS1_k127_3766625_18	1122138.AQUZ01000046_gene349	5.388e-25	108.0	COG0662@1|root,COG0662@2|Bacteria,2I031@201174|Actinobacteria,4DV9N@85009|Propionibacteriales	201174|Actinobacteria	G	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS1_k127_3766625_24	1328313.DS2_01903	1.605e-13	83.0	COG1621@1|root,COG5492@1|root,COG1621@2|Bacteria,COG5492@2|Bacteria,1MWTX@1224|Proteobacteria,1RRZ2@1236|Gammaproteobacteria,465YR@72275|Alteromonadaceae	1224|Proteobacteria	G	Glycosyl hydrolases family 32	scrB	GO:0003674,GO:0003824,GO:0004553,GO:0004564,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005984,GO:0005985,GO:0005987,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016052,GO:0016787,GO:0016798,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044424,GO:0044464,GO:0046352,GO:0071704,GO:1901575	3.2.1.26	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R00802,R02410,R03635,R03921,R06088	RC00028,RC00077	ko00000,ko00001,ko01000	-	GH32	iE2348C_1286.E2348C_2556,iEC55989_1330.EC55989_2656,iECIAI1_1343.ECIAI1_2428,iECSF_1327.ECSF_2568	Glyco_hydro_32C,Glyco_hydro_32N
CMS1_k127_3766625_15	1121904.ARBP01000022_gene3520	8.037e-69	251.0	COG1621@1|root,COG1621@2|Bacteria,4PNCP@976|Bacteroidetes	976|Bacteroidetes	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3766625_0	1304880.JAGB01000001_gene888	6.99e-214	692.0	COG4354@1|root,COG4354@2|Bacteria,1TR78@1239|Firmicutes,247UY@186801|Clostridia	186801|Clostridia	G	beta-glucosidase 2, glycosyl-hydrolase family 116 N-term	-	-	-	-	-	-	-	-	-	-	-	-	DUF608,Glyco_hydr_116N
CMS1_k127_3766625_14	1304880.JAGB01000002_gene2144	2.428e-72	257.0	COG0673@1|root,COG0673@2|Bacteria,1TQ72@1239|Firmicutes,24XW6@186801|Clostridia	186801|Clostridia	S	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_3766625_9	1120950.KB892797_gene2232	2.017e-87	301.0	COG0673@1|root,COG0673@2|Bacteria,2IBFN@201174|Actinobacteria,4DT7Z@85009|Propionibacteriales	201174|Actinobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_3766625_11	313628.LNTAR_12431	2.07e-82	299.0	COG0395@1|root,COG0395@2|Bacteria	2|Bacteria	P	glycerophosphodiester transmembrane transport	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_3766625_3	661478.OP10G_1752	3.236e-139	474.0	COG1175@1|root,COG1653@1|root,COG1175@2|Bacteria,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K02025,ko:K02027,ko:K10201,ko:K15771	ko02010,map02010	M00205,M00207,M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.18,3.A.1.1.2	-	-	BPD_transp_1,SBP_bac_1,SBP_bac_8
CMS1_k127_3766625_27	1242864.D187_000841	0.0007327	51.0	29X33@1|root,30IRP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3766625_25	1397278.AYMV01000001_gene465	7.309e-11	74.0	COG2133@1|root,COG2133@2|Bacteria,2IASI@201174|Actinobacteria,4FMWN@85023|Microbacteriaceae	201174|Actinobacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3785595_0	404589.Anae109_4059	1.266e-98	334.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
CMS1_k127_3785595_1	933262.AXAM01000062_gene944	1.171e-63	230.0	COG1262@1|root,COG4249@1|root,COG1262@2|Bacteria,COG4249@2|Bacteria,1NQ5K@1224|Proteobacteria,42MAT@68525|delta/epsilon subdivisions,2WKY9@28221|Deltaproteobacteria,2MIBZ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PEGA,Peptidase_C14
CMS1_k127_3785595_2	391625.PPSIR1_12803	1.234e-23	118.0	COG4932@1|root,COG4932@2|Bacteria,1PEGG@1224|Proteobacteria,43854@68525|delta/epsilon subdivisions,2X3F3@28221|Deltaproteobacteria,2YVTB@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS1_k127_3787691_1	706587.Desti_2669	4.729e-152	495.0	COG5557@1|root,COG5557@2|Bacteria,1PFX4@1224|Proteobacteria,42NUN@68525|delta/epsilon subdivisions,2WJHN@28221|Deltaproteobacteria,2MQS4@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM Polysulphide reductase, NrfD	dsrP	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
CMS1_k127_3787691_3	706587.Desti_2670	8.922e-99	329.0	COG0437@1|root,COG0437@2|Bacteria,1NBU3@1224|Proteobacteria,42MNU@68525|delta/epsilon subdivisions,2WJRG@28221|Deltaproteobacteria,2MQSD@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	dsrO	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11,Fer4_4
CMS1_k127_3787691_4	485915.Dret_0237	2.232e-37	145.0	arCOG10385@1|root,32SEM@2|Bacteria,1N1IG@1224|Proteobacteria,42TMW@68525|delta/epsilon subdivisions,2WQBW@28221|Deltaproteobacteria,2MC03@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	dsrJ	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3787691_0	264732.Moth_1606	3.697e-304	937.0	COG0247@1|root,COG0247@2|Bacteria,1TSC1@1239|Firmicutes,24B10@186801|Clostridia,42FPP@68295|Thermoanaerobacterales	186801|Clostridia	C	4Fe-4S dicluster domain	hmeD	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
CMS1_k127_3787691_2	335543.Sfum_1146	3.234e-134	434.0	COG2181@1|root,COG2181@2|Bacteria,1R48S@1224|Proteobacteria,42MZU@68525|delta/epsilon subdivisions,2WKKU@28221|Deltaproteobacteria,2MREY@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM Nitrate reductase gamma subunit	dsrM	-	1.7.5.1	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000	5.A.3.1	-	-	Nitrate_red_gam
CMS1_k127_3787691_5	768706.Desor_1697	1.732e-23	104.0	2CDHP@1|root,32RXU@2|Bacteria,1VQ7W@1239|Firmicutes,251NF@186801|Clostridia,265N8@186807|Peptococcaceae	186801|Clostridia	S	RsbT co-antagonist protein rsbRD N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RsbRD_N
CMS1_k127_3792693_4	234267.Acid_7527	1.446e-39	154.0	COG3250@1|root,COG3250@2|Bacteria,3Y2PR@57723|Acidobacteria	57723|Acidobacteria	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.2.1.165	ko:K15855	ko00520,ko01100,map00520,map01100	-	R01966	RC00049	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2
CMS1_k127_3792693_2	671143.DAMO_1462	1.21e-62	225.0	COG4821@1|root,COG4821@2|Bacteria,2NR6C@2323|unclassified Bacteria	2|Bacteria	S	SIS domain	-	-	-	-	-	-	-	-	-	-	-	-	SIS_2
CMS1_k127_3792693_1	360094.PXO_04291	6.689e-63	226.0	COG3568@1|root,COG3568@2|Bacteria,1PPNP@1224|Proteobacteria,1S9D7@1236|Gammaproteobacteria,1X46I@135614|Xanthomonadales	135614|Xanthomonadales	S	Metal-dependent hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CMS1_k127_3792693_8	1179773.BN6_12950	9.922e-11	72.0	COG3025@1|root,COG5607@1|root,COG3025@2|Bacteria,COG5607@2|Bacteria,2GJZH@201174|Actinobacteria,4DY83@85010|Pseudonocardiales	201174|Actinobacteria	S	CHAD	-	-	-	-	-	-	-	-	-	-	-	-	CHAD,CYTH
CMS1_k127_3792693_3	1347342.BN863_6710	5.487e-56	204.0	COG0791@1|root,COG0791@2|Bacteria,4PM8G@976|Bacteroidetes,1IKC6@117743|Flavobacteriia	976|Bacteroidetes	M	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C92
CMS1_k127_3792693_5	404589.Anae109_0574	2.962e-38	157.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,42NIH@68525|delta/epsilon subdivisions,2WN60@28221|Deltaproteobacteria,2YUZ0@29|Myxococcales	28221|Deltaproteobacteria	FP	Ppx/GppA phosphatase family	gppA-2	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
CMS1_k127_3792693_0	1380763.BG53_13575	3.288e-174	586.0	COG3250@1|root,COG3250@2|Bacteria,1TQAM@1239|Firmicutes,4HB7S@91061|Bacilli,26SR5@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
CMS1_k127_3792693_7	439235.Dalk_1339	1.447e-14	87.0	COG3307@1|root,COG3307@2|Bacteria,1N225@1224|Proteobacteria,42QDQ@68525|delta/epsilon subdivisions,2WM6B@28221|Deltaproteobacteria,2MJQS@213118|Desulfobacterales	28221|Deltaproteobacteria	M	O-Antigen ligase	-	-	-	ko:K18814	-	-	-	-	ko00000,ko02000	9.B.67.1	-	-	TPR_14,TPR_16,TPR_8,Wzy_C
CMS1_k127_3792693_9	1121459.AQXE01000005_gene1500	3.31e-05	56.0	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,42P5H@68525|delta/epsilon subdivisions,2WKAU@28221|Deltaproteobacteria,2M8Q5@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_7,TPR_8
CMS1_k127_3792693_6	690850.Desaf_1493	4.109e-26	112.0	COG5000@1|root,COG5000@2|Bacteria,1NU7E@1224|Proteobacteria,42YZ2@68525|delta/epsilon subdivisions,2WTQ1@28221|Deltaproteobacteria,2MHCF@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	signal transduction histidine kinase	-	-	2.7.13.3	ko:K02668,ko:K07709	ko02020,map02020	M00499,M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_10,PAS_4,PAS_9,sCache_3_2
CMS1_k127_3793977_3	1161401.ASJA01000032_gene3019	2.615e-106	360.0	COG1680@1|root,COG1680@2|Bacteria,1MY4Y@1224|Proteobacteria,2TTG4@28211|Alphaproteobacteria,43WAN@69657|Hyphomonadaceae	28211|Alphaproteobacteria	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS1_k127_3793977_7	1117379.BABA_15302	1.311e-84	299.0	COG1621@1|root,COG1621@2|Bacteria,1VSII@1239|Firmicutes,4HUS8@91061|Bacilli	91061|Bacilli	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3793977_10	525904.Tter_2777	1.337e-16	91.0	COG2133@1|root,COG3055@1|root,COG2133@2|Bacteria,COG3055@2|Bacteria,2NPM4@2323|unclassified Bacteria	2|Bacteria	G	Galactose oxidase, central domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,CBM_35,CBM_6,GSDH,Kelch_1,Kelch_6
CMS1_k127_3793977_5	999141.GME_14315	9.365e-102	345.0	COG1819@1|root,COG1819@2|Bacteria,1MW1K@1224|Proteobacteria,1SD4P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	CG	UDP-glucoronosyl and UDP-glucosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	UDPGT
CMS1_k127_3793977_8	1173026.Glo7428_2690	1.954e-79	274.0	COG1028@1|root,COG1028@2|Bacteria,1G67A@1117|Cyanobacteria	1117|Cyanobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS1_k127_3793977_1	682795.AciX8_4785	2.713e-111	370.0	COG0332@1|root,COG0332@2|Bacteria,3Y83G@57723|Acidobacteria	57723|Acidobacteria	H	PFAM 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III	-	-	-	-	-	-	-	-	-	-	-	-	ACP_syn_III_C
CMS1_k127_3793977_6	1242864.D187_000444	1.285e-101	344.0	2CCWM@1|root,338WR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3793977_4	1242864.D187_000445	7.613e-102	340.0	COG1216@1|root,COG1216@2|Bacteria,1N1TF@1224|Proteobacteria,42VI6@68525|delta/epsilon subdivisions,2WRG7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Glycosyl transferase family 2	-	-	-	ko:K12992	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01005	-	GT2	-	Glycos_transf_2
CMS1_k127_3793977_0	158190.SpiGrapes_2262	3.698e-112	376.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	gumH	-	2.4.1.252	ko:K13657	-	-	R09733	RC00005,RC00049	ko00000,ko01000,ko01003	-	GT4	-	Glyco_tran_WecB,Glyco_transf_4,Glycos_transf_1
CMS1_k127_3793977_9	1121406.JAEX01000018_gene2811	2.043e-38	157.0	COG0438@1|root,COG0438@2|Bacteria,1NB81@1224|Proteobacteria,42WA6@68525|delta/epsilon subdivisions,2WRYV@28221|Deltaproteobacteria,2MD0F@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1,SPASM
CMS1_k127_3800617_2	313612.L8106_13405	1.567e-45	173.0	COG1878@1|root,COG1878@2|Bacteria,1G60Q@1117|Cyanobacteria,1HHEV@1150|Oscillatoriales	1117|Cyanobacteria	S	Putative cyclase	-	-	3.5.1.9	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Cyclase
CMS1_k127_3800617_0	247490.KSU1_B0462	1.067e-157	507.0	COG0448@1|root,COG0448@2|Bacteria,2IXP5@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
CMS1_k127_3800617_6	1303518.CCALI_01179	9.573e-14	83.0	COG3408@1|root,COG3408@2|Bacteria	2|Bacteria	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H,GDE_C,SLH
CMS1_k127_3800617_1	269797.Mbar_A1008	1.177e-88	314.0	COG0018@1|root,arCOG00487@2157|Archaea,2XTWP@28890|Euryarchaeota,2N9C5@224756|Methanomicrobia	224756|Methanomicrobia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
CMS1_k127_3800617_5	1125863.JAFN01000001_gene2568	4.265e-19	94.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,42MPK@68525|delta/epsilon subdivisions,2WJM1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	peptidyl-prolyl isomerase	nifM	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
CMS1_k127_3800617_3	1304880.JAGB01000001_gene69	2.599e-31	137.0	COG1459@1|root,COG1459@2|Bacteria,1TQRZ@1239|Firmicutes,249FV@186801|Clostridia	186801|Clostridia	NU	type II secretion system	tapC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
CMS1_k127_3800617_4	289377.HL41_06660	1.299e-21	106.0	COG1459@1|root,COG1459@2|Bacteria,2GGZ5@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	NU	Type II secretion system (T2SS), protein F	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
CMS1_k127_3806707_1	240015.ACP_1727	4.751e-14	74.0	COG1028@1|root,COG1028@2|Bacteria	240015.ACP_1727|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3806707_2	756272.Plabr_2376	1.393e-10	64.0	COG1028@1|root,COG1028@2|Bacteria,2IZC3@203682|Planctomycetes	203682|Planctomycetes	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS1_k127_3806707_0	98439.AJLL01000098_gene2002	1.284e-41	167.0	COG0451@1|root,COG0451@2|Bacteria,1GBXB@1117|Cyanobacteria	1117|Cyanobacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3808725_0	357808.RoseRS_0010	3.893e-66	248.0	COG0823@1|root,COG0823@2|Bacteria,2G8T5@200795|Chloroflexi,376FH@32061|Chloroflexia	32061|Chloroflexia	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
CMS1_k127_3811267_0	1499967.BAYZ01000076_gene823	9.458e-184	581.0	COG2942@1|root,COG2942@2|Bacteria	2|Bacteria	G	2-epimerase	nanE	-	5.1.3.11,5.1.3.8	ko:K01787,ko:K16213	ko00520,map00520	-	R01207,R01445,R10810	RC00289,RC00290	ko00000,ko00001,ko01000	-	-	-	GlcNAc_2-epim
CMS1_k127_3811267_2	143224.JQMD01000002_gene253	1.529e-129	439.0	COG3292@1|root,COG3292@2|Bacteria,4NF9I@976|Bacteroidetes	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
CMS1_k127_3811267_4	1128427.KB904821_gene1999	7.858e-23	111.0	COG0667@1|root,COG0667@2|Bacteria,1G2DX@1117|Cyanobacteria,1H8R6@1150|Oscillatoriales	1117|Cyanobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS1_k127_3811267_3	742725.HMPREF9450_00619	9.666e-55	206.0	COG0407@1|root,COG0407@2|Bacteria,4NTJT@976|Bacteroidetes	976|Bacteroidetes	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
CMS1_k127_3811267_6	234267.Acid_5940	6.735e-06	53.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS1_k127_3811267_1	234267.Acid_3938	1.455e-176	587.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
CMS1_k127_3811267_5	761193.Runsl_2833	2.177e-12	70.0	28KPG@1|root,33QTI@2|Bacteria,4P1AH@976|Bacteroidetes,47U4X@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3814134_4	1379270.AUXF01000001_gene2303	2.138e-24	113.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,1ZUB1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Putative glutamine amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	GATase1_like
CMS1_k127_3814134_3	595460.RRSWK_02337	1.114e-33	144.0	COG4249@1|root,COG4249@2|Bacteria,2IZ2A@203682|Planctomycetes	203682|Planctomycetes	S	Peptidase C14 caspase catalytic subunit p20	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3814134_2	335543.Sfum_3269	3.151e-50	200.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42QJS@68525|delta/epsilon subdivisions,2WKMI@28221|Deltaproteobacteria,2MQZR@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Cache sensor signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,dCache_1
CMS1_k127_3814134_1	589865.DaAHT2_0762	2.12e-122	409.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42PH1@68525|delta/epsilon subdivisions,2WKMX@28221|Deltaproteobacteria,2MJE1@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS1_k127_3814134_0	595460.RRSWK_02559	7.252e-186	601.0	COG0845@1|root,COG0845@2|Bacteria,2IZ22@203682|Planctomycetes	203682|Planctomycetes	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	DUF3347,HlyD_D23
CMS1_k127_3826957_1	1123508.JH636441_gene3779	4.076e-27	116.0	COG0627@1|root,COG0627@2|Bacteria	2|Bacteria	J	Serine hydrolase involved in the detoxification of formaldehyde	-	-	-	-	-	-	-	-	-	-	-	-	Esterase,Hepar_II_III
CMS1_k127_3826957_0	1203611.KB894541_gene1523	6.599e-181	585.0	COG3250@1|root,COG3250@2|Bacteria,4NIBS@976|Bacteroidetes,2FPZ2@200643|Bacteroidia	976|Bacteroidetes	G	alpha-L-rhamnosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106
CMS1_k127_3832352_0	1382306.JNIM01000001_gene2968	2.192e-79	273.0	COG1070@1|root,COG1070@2|Bacteria,2G7ND@200795|Chloroflexi	200795|Chloroflexi	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
CMS1_k127_3832352_1	1304880.JAGB01000002_gene1635	1.728e-47	178.0	COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,247NR@186801|Clostridia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
CMS1_k127_3832352_2	1267534.KB906756_gene625	8.024e-36	150.0	COG1063@1|root,COG1063@2|Bacteria,3Y6II@57723|Acidobacteria,2JKQW@204432|Acidobacteriia	204432|Acidobacteriia	E	Zinc-binding dehydrogenase	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_3841650_2	1379698.RBG1_1C00001G0777	2.152e-43	160.0	COG2864@1|root,COG2864@2|Bacteria,2NQFM@2323|unclassified Bacteria	2|Bacteria	P	Prokaryotic cytochrome b561	cbcY	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Cytochrome_C7,Ni_hydr_CYTB,Paired_CXXCH_1,Rhodanese
CMS1_k127_3841650_1	1254432.SCE1572_01775	1.08e-68	255.0	COG1719@1|root,COG3829@1|root,COG1719@2|Bacteria,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42M2E@68525|delta/epsilon subdivisions,2WKAB@28221|Deltaproteobacteria,2YWDZ@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat,V4R,XylR_N
CMS1_k127_3841650_0	595460.RRSWK_02091	1.518e-73	261.0	COG1609@1|root,COG4977@1|root,COG1609@2|Bacteria,COG4977@2|Bacteria,2IXTX@203682|Planctomycetes	203682|Planctomycetes	K	Xylose operon regulatory protein	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18,Peripla_BP_3
CMS1_k127_3841650_3	756272.Plabr_3099	0.0009222	42.0	COG2165@1|root,COG2165@2|Bacteria,2J50F@203682|Planctomycetes	203682|Planctomycetes	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CMS1_k127_3843633_1	331113.SNE_A12260	1.296e-11	69.0	COG0501@1|root,COG0501@2|Bacteria	2|Bacteria	O	metalloendopeptidase activity	yhfN	GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0070011,GO:0071586,GO:0071704,GO:0080120,GO:0140096,GO:1901564	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
CMS1_k127_3843633_0	1396418.BATQ01000044_gene6477	3.581e-41	163.0	COG2912@1|root,COG2912@2|Bacteria,46X6V@74201|Verrucomicrobia,2IUSE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core2
CMS1_k127_3849956_3	641524.ADICYQ_5911	2.358e-60	231.0	COG1874@1|root,COG1874@2|Bacteria,4P500@976|Bacteroidetes	976|Bacteroidetes	G	Beta-galactosidase	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42
CMS1_k127_3849956_0	344747.PM8797T_07674	5.405e-127	413.0	COG0714@1|root,COG0714@2|Bacteria,2IX1F@203682|Planctomycetes	203682|Planctomycetes	S	ATPase associated with	-	-	-	-	-	-	-	-	-	-	-	-	AAA_3
CMS1_k127_3849956_1	595460.RRSWK_03714	5.871e-122	404.0	COG1721@1|root,COG1721@2|Bacteria,2J13Q@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CMS1_k127_3849956_2	595460.RRSWK_03713	8.617e-87	313.0	COG1305@1|root,COG1305@2|Bacteria,2IZUN@203682|Planctomycetes	203682|Planctomycetes	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
CMS1_k127_3863305_0	575540.Isop_0569	2.548e-199	625.0	COG0673@1|root,COG0673@2|Bacteria,2IWTD@203682|Planctomycetes	203682|Planctomycetes	S	PFAM oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_3863305_1	756272.Plabr_0077	1.515e-83	286.0	COG1082@1|root,COG1082@2|Bacteria,2IWW9@203682|Planctomycetes	203682|Planctomycetes	G	Xylose isomerase domain protein TIM barrel	-	-	5.1.3.30,5.1.3.31	ko:K18910	-	-	R10817,R10818	RC03111,RC03283	ko00000,ko01000	-	-	-	AP_endonuc_2
CMS1_k127_3870142_1	880070.Cycma_2350	6.69e-61	229.0	COG3119@1|root,COG3119@2|Bacteria,4NE7S@976|Bacteroidetes	976|Bacteroidetes	P	COG COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CMS1_k127_3870142_4	1380355.JNIJ01000011_gene989	9.703e-07	62.0	COG2271@1|root,COG2271@2|Bacteria,1MX4V@1224|Proteobacteria,2U6FF@28211|Alphaproteobacteria,3JWSX@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	Major Facilitator Superfamily	uhpC	-	-	ko:K02445	-	-	-	-	ko00000,ko02000	2.A.1.4.3	-	-	MFS_1
CMS1_k127_3870142_3	1122138.AQUZ01000034_gene6381	2.966e-28	132.0	COG2271@1|root,COG2271@2|Bacteria,2GK9E@201174|Actinobacteria	201174|Actinobacteria	G	Sugar phosphate permease	glpT	-	-	ko:K02445	-	-	-	-	ko00000,ko02000	2.A.1.4.3	-	-	MFS_1
CMS1_k127_3870142_0	926550.CLDAP_13850	3.002e-139	452.0	COG0075@1|root,COG0075@2|Bacteria,2G5P3@200795|Chloroflexi	2|Bacteria	E	PFAM aminotransferase class V	phnW	GO:0003674,GO:0003824	2.5.1.49,2.6.1.37,3.11.1.1	ko:K01740,ko:K03430,ko:K05306	ko00270,ko00440,ko01100,ko01120,map00270,map00440,map01100,map01120	-	R00747,R01287,R04152,R04859	RC00008,RC00020,RC00062,RC00368,RC02821,RC02848	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_5
CMS1_k127_3870142_2	1089552.KI911559_gene3164	1.893e-50	184.0	COG0637@1|root,COG0637@2|Bacteria,1MX6B@1224|Proteobacteria,2TTVS@28211|Alphaproteobacteria,2JSAF@204441|Rhodospirillales	204441|Rhodospirillales	S	Belongs to the HAD-like hydrolase superfamily. PhnX family	phnX	-	3.11.1.1	ko:K05306	ko00440,ko01100,ko01120,map00440,map01100,map01120	-	R00747	RC00368	ko00000,ko00001,ko01000	-	-	-	HAD_2
CMS1_k127_3870487_0	382464.ABSI01000010_gene3321	1.373e-23	118.0	COG2706@1|root,COG3210@1|root,COG4733@1|root,COG2706@2|Bacteria,COG3210@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
CMS1_k127_3870955_3	404380.Gbem_0402	7.062e-179	563.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,42MDR@68525|delta/epsilon subdivisions,2WKUR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS1_k127_3870955_2	1382359.JIAL01000001_gene2052	3.345e-190	608.0	COG1064@1|root,COG1064@2|Bacteria,3Y33B@57723|Acidobacteria,2JI1P@204432|Acidobacteriia	204432|Acidobacteriia	S	Zinc-binding dehydrogenase	-	-	-	ko:K13979	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_3870955_6	1380391.JIAS01000003_gene1902	2.545e-48	174.0	COG0599@1|root,COG0599@2|Bacteria,1NN7W@1224|Proteobacteria,2TVCR@28211|Alphaproteobacteria,2JWZS@204441|Rhodospirillales	204441|Rhodospirillales	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS1_k127_3870955_1	1173024.KI912148_gene4415	3.341e-215	688.0	COG2366@1|root,COG2366@2|Bacteria,1G0QT@1117|Cyanobacteria,1JK3D@1189|Stigonemataceae	1117|Cyanobacteria	S	Penicillin amidase	-	-	3.5.1.11,3.5.1.97	ko:K01434,ko:K07116	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
CMS1_k127_3870955_5	1396418.BATQ01000078_gene616	1.469e-52	205.0	COG1621@1|root,COG1621@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 32 family	-	-	3.1.3.6,3.1.4.16	ko:K01119	ko00230,ko00240,map00230,map00240	-	R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135	RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	SLH
CMS1_k127_3870955_7	760192.Halhy_4677	4.955e-05	49.0	COG4278@1|root,COG4278@2|Bacteria,4NR5D@976|Bacteroidetes,1ITC3@117747|Sphingobacteriia	976|Bacteroidetes	H	phenylacetate-CoA ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3870955_4	1297742.A176_06080	6.639e-177	566.0	COG2227@1|root,COG2227@2|Bacteria,1R6E0@1224|Proteobacteria,42ZTU@68525|delta/epsilon subdivisions,2WVFC@28221|Deltaproteobacteria,2YZN2@29|Myxococcales	28221|Deltaproteobacteria	H	RNA repair, ligase-Pnkp-associating, region of Hen1	ubiE2	-	-	-	-	-	-	-	-	-	-	-	Hen1_L,Methyltransf_23
CMS1_k127_3870955_0	1242864.D187_008760	0.0	1145.0	COG0639@1|root,COG4639@1|root,COG0639@2|Bacteria,COG4639@2|Bacteria,1Q3Q7@1224|Proteobacteria,4342C@68525|delta/epsilon subdivisions,2X4TK@28221|Deltaproteobacteria,2YZJY@29|Myxococcales	28221|Deltaproteobacteria	T	PNKP adenylyltransferase domain, ligase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33,Metallophos,PNKP-ligase_C,PNKP_ligase
CMS1_k127_387566_2	338966.Ppro_1017	9.583e-09	61.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	Phage_int_SAM_3,Phage_integrase
CMS1_k127_387566_0	1089553.Tph_c03590	6.453e-112	377.0	arCOG03330@1|root,2Z82Q@2|Bacteria,1U584@1239|Firmicutes,24B07@186801|Clostridia,42FIS@68295|Thermoanaerobacterales	186801|Clostridia	H	Methanol-cobalamin methyltransferase B subunit	-	-	2.1.1.90	ko:K04480	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00356	R04384,R09098	RC00035,RC01144,RC01145,RC02440	ko00000,ko00001,ko00002,ko01000	-	-	-	MtaB
CMS1_k127_387566_3	869213.JCM21142_93472	3.43e-07	53.0	COG5012@1|root,COG5012@2|Bacteria,4P0JY@976|Bacteroidetes	976|Bacteroidetes	S	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
CMS1_k127_387566_1	1499967.BAYZ01000171_gene5584	6.894e-109	364.0	COG0407@1|root,COG0407@2|Bacteria,2NRD5@2323|unclassified Bacteria	2|Bacteria	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
CMS1_k127_3877478_1	180332.JTGN01000003_gene1997	9.505e-103	349.0	COG0407@1|root,COG0407@2|Bacteria,1VEQ3@1239|Firmicutes,24RQ2@186801|Clostridia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
CMS1_k127_3877478_2	1121011.AUCB01000028_gene3088	0.0002372	48.0	COG3250@1|root,COG3345@1|root,COG3250@2|Bacteria,COG3345@2|Bacteria,4NMDV@976|Bacteroidetes	976|Bacteroidetes	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3877478_0	530564.Psta_1668	7.269e-116	387.0	COG1520@1|root,COG1520@2|Bacteria,2IY7A@203682|Planctomycetes	203682|Planctomycetes	S	COG1520 FOG WD40-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
CMS1_k127_3879184_1	1168034.FH5T_18125	1.018e-71	253.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CMS1_k127_3879184_0	1168034.FH5T_01525	1.908e-117	392.0	COG0438@1|root,COG0438@2|Bacteria,4P10Z@976|Bacteroidetes	976|Bacteroidetes	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
CMS1_k127_3879184_4	485914.Hmuk_3300	1.267e-25	121.0	COG0515@1|root,COG1520@1|root,arCOG02482@2157|Archaea,arCOG03682@2157|Archaea,2XUI1@28890|Euryarchaeota,240TC@183963|Halobacteria	183963|Halobacteria	C	COG1520 FOG WD40-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ,PQQ_2,PQQ_3
CMS1_k127_3879184_3	1123242.JH636434_gene3519	4.274e-67	235.0	COG1136@1|root,COG1136@2|Bacteria,2IZ2X@203682|Planctomycetes	203682|Planctomycetes	V	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	-	-	-	ko:K02003,ko:K09810	ko02010,map02010	M00255,M00258	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.125	-	-	ABC_tran
CMS1_k127_3879184_2	497964.CfE428DRAFT_4943	2.939e-70	253.0	COG0577@1|root,COG0577@2|Bacteria,46U6N@74201|Verrucomicrobia	74201|Verrucomicrobia	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
CMS1_k127_3894188_1	679199.HMPREF9332_01395	3.359e-82	302.0	COG3525@1|root,COG3525@2|Bacteria,4NEQN@976|Bacteroidetes,2FMUE@200643|Bacteroidia	976|Bacteroidetes	G	F5 8 type C domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4838,F5_F8_type_C,Glyco_hydro_67N
CMS1_k127_3894188_2	391615.ABSJ01000030_gene823	7.906e-50	187.0	COG1309@1|root,COG1309@2|Bacteria,1RA5Z@1224|Proteobacteria,1S3A4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	COG1309 Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS1_k127_3894188_3	314230.DSM3645_14015	3.25e-14	83.0	COG2165@1|root,COG2165@2|Bacteria,2IXWM@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CMS1_k127_3894188_0	344747.PM8797T_29758	6.771e-182	573.0	COG4102@1|root,COG4102@2|Bacteria,2J4YY@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CMS1_k127_389559_0	225937.HP15_406	5.002e-273	854.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,1RMS9@1236|Gammaproteobacteria,464B1@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
CMS1_k127_3900918_2	269799.Gmet_1500	1.854e-18	99.0	29R89@1|root,30C9N@2|Bacteria,1NTEP@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3900918_1	390989.JOEG01000030_gene1702	2.738e-32	145.0	COG1595@1|root,COG1595@2|Bacteria,2GK6V@201174|Actinobacteria	201174|Actinobacteria	K	GxGYxYP putative glycoside hydrolase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	GxGYxYP_C,GxGYxYP_N
CMS1_k127_3900918_0	160799.PBOR_18590	1.146e-92	338.0	COG1470@1|root,COG1874@1|root,COG1470@2|Bacteria,COG1874@2|Bacteria,1TZWH@1239|Firmicutes,4I95Z@91061|Bacilli,2712A@186822|Paenibacillaceae	91061|Bacilli	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,Glyco_hydro_42
CMS1_k127_3900918_3	1227488.C477_17500	3.169e-06	61.0	COG3250@1|root,arCOG07813@1|root,arCOG07337@2157|Archaea,arCOG07813@2157|Archaea,2XT0P@28890|Euryarchaeota,23SAY@183963|Halobacteria	183963|Halobacteria	G	COG3250 Beta-galactosidase beta-glucuronidase	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Laminin_G_3
CMS1_k127_3900918_4	243090.RB7229	5.585e-05	53.0	COG2010@1|root,COG2010@2|Bacteria,2IYDW@203682|Planctomycetes	203682|Planctomycetes	C	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PSCyt1,PSCyt2,PSD1
CMS1_k127_3905314_0	358681.BBR47_48990	1.603e-117	389.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1TR8J@1239|Firmicutes,4H9XN@91061|Bacilli,26TYA@186822|Paenibacillaceae	91061|Bacilli	I	3-hydroxyacyl-CoA dehydrogenase	fadN	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU32840	3HCDH,3HCDH_N,ECH_1
CMS1_k127_3923581_1	234267.Acid_4005	1.032e-232	737.0	COG1053@1|root,COG1053@2|Bacteria,3Y6S5@57723|Acidobacteria	57723|Acidobacteria	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
CMS1_k127_3923581_8	1121085.AUCI01000007_gene1228	7.384e-11	72.0	COG0388@1|root,COG0388@2|Bacteria,1V4HM@1239|Firmicutes,4IQ6E@91061|Bacilli,1ZRHK@1386|Bacillus	91061|Bacilli	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
CMS1_k127_3923581_2	1267535.KB906767_gene2459	7.632e-191	624.0	COG1874@1|root,COG1874@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	3.2.1.23,3.2.1.4	ko:K01179,ko:K01190,ko:K12308	ko00052,ko00500,ko00511,ko00600,ko01100,map00052,map00500,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114,R06200,R11307,R11308	RC00049,RC00452	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_6,DUF4832,DUF4978,FIVAR,Glyco_hydro_42,Glyco_hydro_42M
CMS1_k127_3923581_3	1201290.M902_3233	2.562e-131	434.0	COG0276@1|root,COG0477@1|root,COG0276@2|Bacteria,COG2814@2|Bacteria,1MVR1@1224|Proteobacteria,42M0C@68525|delta/epsilon subdivisions,2MURR@213481|Bdellovibrionales,2X5EE@28221|Deltaproteobacteria	213481|Bdellovibrionales	EGHP	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	-	-	-	-	-	-	-	-	-	-	Ferrochelatase,MFS_1
CMS1_k127_3923581_0	1499967.BAYZ01000095_gene4126	5.156e-273	851.0	COG2192@1|root,COG2192@2|Bacteria,2NNRR@2323|unclassified Bacteria	2|Bacteria	O	Carbamoyltransferase C-terminus	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
CMS1_k127_3923581_10	402777.KB235903_gene661	1.47e-07	58.0	2DP8V@1|root,33122@2|Bacteria,1G83J@1117|Cyanobacteria,1HB8R@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3923581_9	1121456.ATVA01000014_gene680	5.776e-10	61.0	2EGPU@1|root,33AFZ@2|Bacteria,1NH69@1224|Proteobacteria,42X36@68525|delta/epsilon subdivisions,2WSNU@28221|Deltaproteobacteria,2MDMZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3923581_6	888055.HMPREF9015_01338	2.244e-21	104.0	COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,379DH@32066|Fusobacteria	32066|Fusobacteria	G	PTS system, fructose-specific IIB	fruA	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
CMS1_k127_3923581_11	694431.DESACE_05150	0.0004837	51.0	COG1579@1|root,COG1579@2|Bacteria,1R7GT@1224|Proteobacteria,42P3S@68525|delta/epsilon subdivisions,2WSCV@28221|Deltaproteobacteria,2M6CB@213113|Desulfurellales	28221|Deltaproteobacteria	S	C4-type zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
CMS1_k127_3923581_7	502025.Hoch_4460	2.874e-17	87.0	COG0664@1|root,COG0664@2|Bacteria,1NBX3@1224|Proteobacteria,42UGQ@68525|delta/epsilon subdivisions,2WQY8@28221|Deltaproteobacteria,2YVI9@29|Myxococcales	28221|Deltaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
CMS1_k127_3923581_4	1173028.ANKO01000094_gene2611	5.362e-88	306.0	COG1680@1|root,COG1680@2|Bacteria,1G6GD@1117|Cyanobacteria,1HBFP@1150|Oscillatoriales	1117|Cyanobacteria	V	Beta-lactamase	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase
CMS1_k127_3923581_5	1121124.JNIX01000008_gene2550	4.069e-43	163.0	COG4262@1|root,COG4262@2|Bacteria,1QUPY@1224|Proteobacteria,2TYBU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3931720_3	497964.CfE428DRAFT_3131	3.106e-58	211.0	COG1335@1|root,COG1335@2|Bacteria	2|Bacteria	Q	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	-	-	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase,ThuA
CMS1_k127_3931720_1	243090.RB9026	1.474e-164	529.0	COG0673@1|root,COG0673@2|Bacteria,2IX39@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_3931720_0	240016.ABIZ01000001_gene1332	9.719e-189	602.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS1_k127_3931720_2	468059.AUHA01000003_gene1874	8.27e-114	381.0	COG3000@1|root,COG3000@2|Bacteria,4NFWX@976|Bacteroidetes,1IPCD@117747|Sphingobacteriia	976|Bacteroidetes	I	PFAM Fatty acid hydroxylase	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
CMS1_k127_3931720_5	518766.Rmar_1256	7.281e-51	186.0	COG0053@1|root,COG0053@2|Bacteria,4NEID@976|Bacteroidetes,1FJ56@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	fieF	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
CMS1_k127_3934340_5	391625.PPSIR1_32457	8.388e-24	107.0	COG1597@1|root,COG1597@2|Bacteria,1RCJT@1224|Proteobacteria,42W6W@68525|delta/epsilon subdivisions,2X6V3@28221|Deltaproteobacteria,2YUYD@29|Myxococcales	28221|Deltaproteobacteria	I	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
CMS1_k127_3934340_2	1267535.KB906767_gene1663	6.156e-71	264.0	COG4257@1|root,COG4257@2|Bacteria	2|Bacteria	V	antibiotic catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF5011,SLH
CMS1_k127_3934340_4	338963.Pcar_2289	2.089e-31	128.0	2EHW5@1|root,33BMQ@2|Bacteria,1P29Q@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3934340_3	756067.MicvaDRAFT_3584	1.896e-52	196.0	COG5285@1|root,COG5285@2|Bacteria,1GGV9@1117|Cyanobacteria	1117|Cyanobacteria	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
CMS1_k127_3934340_7	593750.Metfor_0015	0.0005654	52.0	arCOG02527@1|root,arCOG04987@1|root,arCOG02527@2157|Archaea,arCOG04987@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
CMS1_k127_3934340_0	1122927.KB895414_gene5140	5.247e-134	444.0	COG3669@1|root,COG3669@2|Bacteria,1TSG7@1239|Firmicutes,4HEKS@91061|Bacilli,26UH5@186822|Paenibacillaceae	91061|Bacilli	G	alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,F5_F8_type_C
CMS1_k127_3934340_1	935948.KE386494_gene310	7.424e-94	318.0	COG1554@1|root,COG1554@2|Bacteria,1TPKN@1239|Firmicutes,248K8@186801|Clostridia,42HTX@68295|Thermoanaerobacterales	186801|Clostridia	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K15923	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	GH95	-	Glyco_hyd_65N_2
CMS1_k127_3935639_0	522306.CAP2UW1_2609	5.382e-53	199.0	COG1192@1|root,COG1357@1|root,COG1787@1|root,COG2319@1|root,COG5635@1|root,COG1192@2|Bacteria,COG1357@2|Bacteria,COG1787@2|Bacteria,COG2319@2|Bacteria,COG5635@2|Bacteria,1MWJA@1224|Proteobacteria,2VI8Q@28216|Betaproteobacteria	28216|Betaproteobacteria	V	WD40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	NACHT,Pentapeptide,WD40
CMS1_k127_3935639_2	1278073.MYSTI_06103	6.445e-07	62.0	2CG09@1|root,2ZDCX@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1579)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1579
CMS1_k127_3935639_1	443143.GM18_1106	1.058e-15	87.0	COG2373@1|root,COG2931@1|root,COG4932@1|root,COG2373@2|Bacteria,COG2931@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	A2M,An_peroxidase,CHRD,CarboxypepD_reg
CMS1_k127_394084_8	439235.Dalk_2376	1.866e-35	143.0	COG1413@1|root,COG1413@2|Bacteria,1R6G4@1224|Proteobacteria,42T2X@68525|delta/epsilon subdivisions,2WPNC@28221|Deltaproteobacteria,2MKIT@213118|Desulfobacterales	28221|Deltaproteobacteria	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_EZ
CMS1_k127_394084_1	760568.Desku_2155	1.984e-152	497.0	COG3829@1|root,COG3829@2|Bacteria,1V0EF@1239|Firmicutes,24DXA@186801|Clostridia	186801|Clostridia	KT	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,PAS_9,Sigma54_activat
CMS1_k127_394084_5	706587.Desti_5326	2.538e-63	232.0	COG3852@1|root,COG3852@2|Bacteria,1R1JU@1224|Proteobacteria,43DA4@68525|delta/epsilon subdivisions,2X8GR@28221|Deltaproteobacteria	2|Bacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	regM	-	2.7.13.3	ko:K02668,ko:K07709	ko02020,map02020	M00499,M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS,PAS_9,Response_reg
CMS1_k127_394084_10	706587.Desti_0283	1.378e-24	109.0	COG0745@1|root,COG0745@2|Bacteria,1NBQZ@1224|Proteobacteria,42V8P@68525|delta/epsilon subdivisions,2WS87@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS1_k127_394084_9	706587.Desti_0283	1.222e-30	125.0	COG0745@1|root,COG0745@2|Bacteria,1NBQZ@1224|Proteobacteria,42V8P@68525|delta/epsilon subdivisions,2WS87@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS1_k127_394084_0	411464.DESPIG_00086	6.889e-230	722.0	COG0247@1|root,COG0247@2|Bacteria,1R7N6@1224|Proteobacteria,42QFE@68525|delta/epsilon subdivisions,2WKFM@28221|Deltaproteobacteria,2MAAJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
CMS1_k127_394084_6	693661.Arcve_1696	3.094e-58	214.0	COG2181@1|root,arCOG02196@2157|Archaea	2157|Archaea	C	PFAM Nitrate reductase gamma subunit	-	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_gam
CMS1_k127_394084_12	760568.Desku_2154	1.839e-08	62.0	COG1433@1|root,COG1433@2|Bacteria,1VM57@1239|Firmicutes,24WD4@186801|Clostridia	186801|Clostridia	S	Dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	Nitro_FeMo-Co
CMS1_k127_394084_2	1121468.AUBR01000069_gene1118	7.151e-86	301.0	COG0247@1|root,COG0479@1|root,COG0247@2|Bacteria,COG0479@2|Bacteria,1UXXR@1239|Firmicutes,24BGG@186801|Clostridia,42F4S@68295|Thermoanaerobacterales	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
CMS1_k127_394084_11	289376.THEYE_A1285	1.077e-23	110.0	COG2181@1|root,COG2181@2|Bacteria	2|Bacteria	C	nitrate reductase activity	tmcC	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_gam
CMS1_k127_394084_4	945713.IALB_2426	5.063e-72	252.0	COG0437@1|root,COG0437@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	fdnH	-	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Fer4_11,Fer4_3,Fer4_4
CMS1_k127_394084_3	234267.Acid_4205	4.233e-79	288.0	COG5557@1|root,COG5557@2|Bacteria,3Y3RF@57723|Acidobacteria	57723|Acidobacteria	C	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
CMS1_k127_394084_7	1121904.ARBP01000060_gene1913	3.633e-36	147.0	COG3292@1|root,COG3292@2|Bacteria,4P1XS@976|Bacteroidetes,47U9C@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3955320_0	926550.CLDAP_02260	1.994e-151	494.0	COG0613@1|root,COG2865@1|root,COG0613@2|Bacteria,COG2865@2|Bacteria,2G5UU@200795|Chloroflexi	200795|Chloroflexi	K	SMART phosphoesterase PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2,PHP
CMS1_k127_3964264_1	66875.JODY01000002_gene5008	0.0003768	50.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3964264_0	555079.Toce_1876	8.665e-50	185.0	COG0524@1|root,COG0524@2|Bacteria,1UVW9@1239|Firmicutes,25MKQ@186801|Clostridia,42IEM@68295|Thermoanaerobacterales	186801|Clostridia	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
CMS1_k127_3975268_2	397278.JOJN01000016_gene2393	1.424e-12	76.0	COG0640@1|root,COG0640@2|Bacteria,2IKUI@201174|Actinobacteria,4DRSJ@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
CMS1_k127_3975268_1	1286632.P278_23830	3.684e-19	94.0	COG3577@1|root,COG3577@2|Bacteria,4NNI0@976|Bacteroidetes,1I1Z6@117743|Flavobacteriia	976|Bacteroidetes	S	protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2
CMS1_k127_3975268_0	913325.N799_11695	2.305e-90	312.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RQTU@1236|Gammaproteobacteria,1X57C@135614|Xanthomonadales	135614|Xanthomonadales	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
CMS1_k127_3975268_3	1535287.JP74_03080	4.035e-07	52.0	COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,2TQS7@28211|Alphaproteobacteria,3N6AJ@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	gor	GO:0000166,GO:0000302,GO:0000305,GO:0003674,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0010035,GO:0017076,GO:0019725,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0045454,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0065007,GO:0065008,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901700	1.8.1.7	ko:K00383	ko00480,ko04918,map00480,map04918	-	R00094,R00115	RC00011	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
CMS1_k127_3976924_1	945713.IALB_1007	6.539e-104	362.0	COG0383@1|root,COG0383@2|Bacteria	2|Bacteria	G	mannose metabolic process	mngB	GO:0003674,GO:0003824,GO:0004553,GO:0004559,GO:0005975,GO:0005996,GO:0006013,GO:0006464,GO:0006517,GO:0006807,GO:0008150,GO:0008152,GO:0009100,GO:0009987,GO:0015923,GO:0016787,GO:0016798,GO:0019318,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0071704,GO:1901135,GO:1901564	3.2.1.170,3.2.1.24	ko:K01191,ko:K15524	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	iEcolC_1368.EcolC_2924,iSF_1195.SF0565,iSFxv_1172.SFxv_0623,iS_1188.S0578	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
CMS1_k127_3976924_0	697281.Mahau_0033	5.413e-266	852.0	COG0383@1|root,COG0383@2|Bacteria,1TQEH@1239|Firmicutes,248VH@186801|Clostridia,42FU3@68295|Thermoanaerobacterales	186801|Clostridia	G	glycosyl hydrolase 38 domain protein	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
CMS1_k127_3978462_0	641524.ADICYQ_2788	7.041e-18	97.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	3.2.1.18,3.2.1.4	ko:K01179,ko:K01186	ko00500,ko00511,ko00600,ko01100,ko04142,map00500,map00511,map00600,map01100,map04142	-	R04018,R06200,R11307,R11308	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33,GH5,GH9	-	BNR_2,BNR_3,CelD_N,Dockerin_1,Glyco_hydro_9
CMS1_k127_3978462_1	1249634.D781_2674	4.886e-09	68.0	COG3934@1|root,COG3934@2|Bacteria,1QVN8@1224|Proteobacteria,1RUKS@1236|Gammaproteobacteria,402VC@613|Serratia	1236|Gammaproteobacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3982766_14	323261.Noc_2891	0.0009022	49.0	COG4967@1|root,COG4967@2|Bacteria,1N992@1224|Proteobacteria,1T2RT@1236|Gammaproteobacteria,1WZB5@135613|Chromatiales	135613|Chromatiales	U	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02458	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
CMS1_k127_3982766_11	243164.DET0134	1.201e-05	56.0	COG2165@1|root,COG2165@2|Bacteria,2GAUM@200795|Chloroflexi,34DDU@301297|Dehalococcoidia	301297|Dehalococcoidia	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
CMS1_k127_3982766_4	886293.Sinac_6457	1.156e-110	370.0	COG1459@1|root,COG1459@2|Bacteria,2IX2A@203682|Planctomycetes	203682|Planctomycetes	NU	Type II secretory pathway component PulF	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
CMS1_k127_3982766_1	1123242.JH636437_gene5940	3.831e-161	526.0	COG2804@1|root,COG2804@2|Bacteria,2IXGK@203682|Planctomycetes	203682|Planctomycetes	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
CMS1_k127_3982766_3	313628.LNTAR_05914	3.322e-131	429.0	COG2805@1|root,COG2805@2|Bacteria	2|Bacteria	NU	Type II/IV secretion system protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
CMS1_k127_3982766_2	794903.OPIT5_27205	5.364e-157	516.0	COG2804@1|root,COG2804@2|Bacteria,46SDR@74201|Verrucomicrobia,3K77E@414999|Opitutae	414999|Opitutae	NU	General secretory system II protein E domain protein	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
CMS1_k127_3982766_9	1121405.dsmv_0462	1.295e-12	81.0	COG4972@1|root,COG4972@2|Bacteria,1MYIB@1224|Proteobacteria,42SIX@68525|delta/epsilon subdivisions,2WP1G@28221|Deltaproteobacteria,2MKAU@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	Fimbrial assembly family protein	gspL	-	-	ko:K02461	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	GspL_C,PilM_2,PilN,T2SSL
CMS1_k127_3982766_8	243231.GSU0322	1.478e-26	122.0	COG3156@1|root,COG3156@2|Bacteria,1N9I4@1224|Proteobacteria,42V0N@68525|delta/epsilon subdivisions,2WRR8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	PFAM General secretion pathway protein K	gspK	-	-	ko:K02460	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSK
CMS1_k127_3982766_13	344747.PM8797T_14299	0.0003327	52.0	COG4795@1|root,COG4795@2|Bacteria,2J03I@203682|Planctomycetes	203682|Planctomycetes	U	General secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
CMS1_k127_3982766_7	443143.GM18_3762	1.219e-34	141.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,42SFB@68525|delta/epsilon subdivisions,2WP3B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	general secretion pathway protein G	gspG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
CMS1_k127_3982766_5	404589.Anae109_0728	2.324e-100	340.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42MH9@68525|delta/epsilon subdivisions,2WJE0@28221|Deltaproteobacteria,2YTZT@29|Myxococcales	28221|Deltaproteobacteria	U	General secretion pathway protein F	gspF	-	-	ko:K02455,ko:K02653	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
CMS1_k127_3982766_0	1232410.KI421418_gene2157	2.642e-171	557.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,43UCA@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	Type II secretion system (T2SS), protein E, N-terminal domain	gspE	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
CMS1_k127_3982766_6	1232410.KI421418_gene2158	2.285e-79	295.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,42M9I@68525|delta/epsilon subdivisions,2WK1H@28221|Deltaproteobacteria,43UC5@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	Bacterial type II/III secretion system short domain	gspD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
CMS1_k127_3982766_12	215803.DB30_5332	0.0001064	53.0	COG3031@1|root,COG3031@2|Bacteria,1NB50@1224|Proteobacteria,42WPG@68525|delta/epsilon subdivisions,2WREX@28221|Deltaproteobacteria,2YVJ9@29|Myxococcales	28221|Deltaproteobacteria	U	General secretion pathway protein C	gspC	-	-	ko:K02452	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	PDZ_2,T2SSC
CMS1_k127_3982766_10	246197.MXAN_2676	5.51e-10	73.0	2EHJS@1|root,33BBN@2|Bacteria,1NP80@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3983556_3	869213.JCM21142_2770	3.375e-39	157.0	COG3317@1|root,COG3317@2|Bacteria,4NVVX@976|Bacteroidetes	976|Bacteroidetes	M	Carbohydrate esterase, sialic acid-specific acetylesterase	-	-	-	-	-	-	-	-	-	-	-	-	SASA
CMS1_k127_3983556_1	439235.Dalk_5200	1.416e-113	417.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria	1224|Proteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	FecR,HCBP_related,HemolysinCabind
CMS1_k127_3983556_2	1121272.KB903261_gene5952	4.519e-42	181.0	COG0584@1|root,COG5184@1|root,COG0584@2|Bacteria,COG5184@2|Bacteria,2GTZZ@201174|Actinobacteria	201174|Actinobacteria	CDZ	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3983556_6	378806.STAUR_2350	4.811e-09	72.0	COG3568@1|root,COG3568@2|Bacteria,1N2ZJ@1224|Proteobacteria,42WUR@68525|delta/epsilon subdivisions,2WSUA@28221|Deltaproteobacteria,2YUA6@29|Myxococcales	28221|Deltaproteobacteria	PQ	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos,LTD
CMS1_k127_3983556_0	1122939.ATUD01000001_gene577	1.486e-193	674.0	COG1520@1|root,COG1520@2|Bacteria,2H3K4@201174|Actinobacteria,4CRJK@84995|Rubrobacteria	84995|Rubrobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3983556_4	177439.DP1549	5.992e-20	98.0	COG1309@1|root,COG1309@2|Bacteria,1RG05@1224|Proteobacteria,42RA4@68525|delta/epsilon subdivisions,2WSC5@28221|Deltaproteobacteria,2MPRE@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS1_k127_3983556_5	247490.KSU1_C1333	1.88e-17	92.0	COG4968@1|root,COG4968@2|Bacteria,2J519@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CMS1_k127_3985477_1	118161.KB235922_gene1235	1.24e-32	130.0	COG2304@1|root,COG2931@1|root,COG2304@2|Bacteria,COG2931@2|Bacteria,1G2XZ@1117|Cyanobacteria	1117|Cyanobacteria	Q	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_3,DUF4347,FG-GAP_2,VCBS
CMS1_k127_3985477_0	1303518.CCALI_00612	2.394e-239	777.0	COG0383@1|root,COG0383@2|Bacteria	2|Bacteria	G	mannose metabolic process	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
CMS1_k127_3988799_2	1054213.HMPREF9946_00675	1.212e-73	257.0	COG4589@1|root,COG4589@2|Bacteria,1MX58@1224|Proteobacteria,2TT9I@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Phosphatidate cytidylyltransferase	cdsA2	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
CMS1_k127_3988799_1	886293.Sinac_7153	5.137e-75	263.0	COG0204@1|root,COG0204@2|Bacteria,2IWS6@203682|Planctomycetes	203682|Planctomycetes	I	Acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
CMS1_k127_3988799_0	204669.Acid345_4052	3.808e-162	526.0	COG0204@1|root,COG0318@1|root,COG0477@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,COG2814@2|Bacteria,3Y4RT@57723|Acidobacteria	57723|Acidobacteria	IQ	Phosphate acyltransferases	-	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase,MFS_1
CMS1_k127_3990836_4	880072.Desac_0186	3.087e-05	48.0	COG1943@1|root,COG1943@2|Bacteria,1P19I@1224|Proteobacteria,42PP3@68525|delta/epsilon subdivisions,2X227@28221|Deltaproteobacteria,2MQQ2@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
CMS1_k127_3990836_3	449447.MAE_09140	3.768e-25	109.0	COG1724@1|root,COG1724@2|Bacteria,1G8K9@1117|Cyanobacteria	1117|Cyanobacteria	N	PFAM YcfA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
CMS1_k127_3990836_2	880073.Calab_3411	1.369e-25	107.0	COG1598@1|root,COG1598@2|Bacteria,2NQ8D@2323|unclassified Bacteria	2|Bacteria	S	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
CMS1_k127_3990836_1	1303518.CCALI_01947	7.3e-45	174.0	COG1560@1|root,COG1560@2|Bacteria	2|Bacteria	M	Kdo2-lipid A biosynthetic process	htrB	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
CMS1_k127_3990836_0	945713.IALB_2671	3.168e-82	290.0	COG1236@1|root,COG1236@2|Bacteria	2|Bacteria	J	nucleic acid phosphodiester bond hydrolysis	-	-	-	ko:K07576,ko:K07577	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_2,Lactamase_B_6,RMMBL
CMS1_k127_3993262_4	1121447.JONL01000001_gene808	1.49e-57	209.0	COG0845@1|root,COG0845@2|Bacteria,1RI9S@1224|Proteobacteria,42PDM@68525|delta/epsilon subdivisions,2WMKT@28221|Deltaproteobacteria,2M99P@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
CMS1_k127_3993262_0	690850.Desaf_0355	0.0	1218.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2M9AP@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
CMS1_k127_3993262_2	655815.ZPR_2511	1.239e-71	251.0	COG0584@1|root,COG0584@2|Bacteria,4NMWE@976|Bacteroidetes	976|Bacteroidetes	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
CMS1_k127_3993262_1	1303518.CCALI_00565	5.554e-95	340.0	COG3292@1|root,COG3292@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
CMS1_k127_3993262_6	945713.IALB_1355	0.0003834	51.0	COG1729@1|root,COG1729@2|Bacteria	2|Bacteria	S	protein trimerization	-	-	-	-	-	-	-	-	-	-	-	-	PEGA,TPR_16,TPR_2,TPR_6,TPR_8
CMS1_k127_3993262_7	648996.Theam_1645	0.0008163	48.0	2EIXF@1|root,33CNP@2|Bacteria,2G4DD@200783|Aquificae	200783|Aquificae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3993262_3	1267534.KB906758_gene2338	2.2e-59	211.0	COG0667@1|root,COG0667@2|Bacteria,3Y6M9@57723|Acidobacteria,2JM6A@204432|Acidobacteriia	204432|Acidobacteriia	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS1_k127_3997761_9	880070.Cycma_2352	2.019e-33	136.0	COG3669@1|root,COG3669@2|Bacteria,4NHRG@976|Bacteroidetes,47TRP@768503|Cytophagia	976|Bacteroidetes	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos
CMS1_k127_3997761_6	396588.Tgr7_2436	6.492e-46	169.0	COG1487@1|root,COG1487@2|Bacteria,1QU3C@1224|Proteobacteria	1224|Proteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	vapC	-	-	-	-	-	-	-	-	-	-	-	PIN
CMS1_k127_3997761_12	396588.Tgr7_2437	5.9e-20	91.0	COG2002@1|root,COG2002@2|Bacteria,1NBUR@1224|Proteobacteria,1SSDG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	SpoVT / AbrB like domain	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
CMS1_k127_3997761_3	1288963.ADIS_1946	2.954e-80	278.0	COG5285@1|root,COG5285@2|Bacteria,4NHQ6@976|Bacteroidetes,47NC5@768503|Cytophagia	976|Bacteroidetes	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
CMS1_k127_3997761_11	379066.GAU_1901	3.016e-25	117.0	COG0758@1|root,COG0758@2|Bacteria,1ZTW4@142182|Gemmatimonadetes	142182|Gemmatimonadetes	LU	DNA recombination-mediator protein A	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
CMS1_k127_3997761_1	926550.CLDAP_02840	2.362e-96	331.0	COG2723@1|root,COG2723@2|Bacteria,2G5QE@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycoside hydrolase, family 1	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
CMS1_k127_3997761_4	205914.HS_0335	4.531e-65	246.0	COG2103@1|root,COG2103@2|Bacteria,1MVDR@1224|Proteobacteria,1RN3P@1236|Gammaproteobacteria,1Y8A3@135625|Pasteurellales	135625|Pasteurellales	S	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS,SIS_2
CMS1_k127_3997761_5	246197.MXAN_3045	4.716e-60	228.0	COG2385@1|root,COG2385@2|Bacteria,1RGJS@1224|Proteobacteria,42RZE@68525|delta/epsilon subdivisions,2WNH8@28221|Deltaproteobacteria,2YTWF@29|Myxococcales	28221|Deltaproteobacteria	D	Stage II sporulation protein	-	-	-	-	-	-	-	-	-	-	-	-	SpoIID
CMS1_k127_3997761_2	273068.TTE0217	1.517e-82	288.0	COG2377@1|root,COG2377@2|Bacteria,1TSBU@1239|Firmicutes,247S1@186801|Clostridia,42HVC@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
CMS1_k127_3997761_8	1267535.KB906767_gene1935	7.199e-38	165.0	COG1572@1|root,COG1572@2|Bacteria,3Y8B5@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4091)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4091
CMS1_k127_3997761_10	1177594.MIC448_2190018	9.997e-32	135.0	COG1266@1|root,COG1266@2|Bacteria,2I8AH@201174|Actinobacteria,4FREE@85023|Microbacteriaceae	201174|Actinobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
CMS1_k127_3997761_0	945713.IALB_1905	2.326e-128	433.0	COG0591@1|root,COG0591@2|Bacteria	2|Bacteria	E	symporter activity	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
CMS1_k127_3997761_7	1121920.AUAU01000001_gene2240	2.59e-40	153.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,Thioredoxin,Thioredoxin_9
CMS1_k127_4001533_0	756272.Plabr_2856	1.856e-139	451.0	COG3119@1|root,COG3119@2|Bacteria,2IXIB@203682|Planctomycetes	203682|Planctomycetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS1_k127_4008305_2	794903.OPIT5_12400	0.0003866	54.0	COG5434@1|root,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_49N,Hepar_II_III,Hepar_II_III_N
CMS1_k127_4008305_0	1122605.KB893649_gene3749	5.838e-173	558.0	COG3119@1|root,COG3119@2|Bacteria,4NEQ5@976|Bacteroidetes,1IRRQ@117747|Sphingobacteriia	2|Bacteria	P	PFAM sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CMS1_k127_4008305_1	234267.Acid_7897	8.301e-98	345.0	COG3303@1|root,COG3303@2|Bacteria,3Y84F@57723|Acidobacteria	57723|Acidobacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4021086_2	452637.Oter_2196	7.187e-31	125.0	COG0673@1|root,COG0673@2|Bacteria,46U95@74201|Verrucomicrobia,3K969@414999|Opitutae	414999|Opitutae	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_4021086_0	1123277.KB893217_gene4619	8.068e-153	494.0	COG2942@1|root,COG2942@2|Bacteria,4NHTQ@976|Bacteroidetes,47KVQ@768503|Cytophagia	976|Bacteroidetes	G	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)	-	-	5.1.3.11	ko:K16213	-	-	R01445,R10810	RC00289	ko00000,ko01000	-	-	-	GlcNAc_2-epim
CMS1_k127_4021086_3	583355.Caka_2889	1.129e-18	89.0	2AA1Q@1|root,337NJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4021086_4	1122604.JONR01000003_gene1555	1.305e-16	86.0	2AA1Q@1|root,30ZAD@2|Bacteria,1R38Z@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4021086_1	240016.ABIZ01000001_gene1135	3.157e-48	177.0	COG1943@1|root,COG1943@2|Bacteria,46W84@74201|Verrucomicrobia,2IVXZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
CMS1_k127_4022488_9	886293.Sinac_7396	2.581e-44	172.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
CMS1_k127_4022488_2	1192034.CAP_5764	2.553e-157	506.0	COG4690@1|root,COG4690@2|Bacteria,1RBRZ@1224|Proteobacteria	1224|Proteobacteria	E	dipeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C69
CMS1_k127_4022488_12	1125863.JAFN01000001_gene2904	1.271e-22	104.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	PFAM Type II secretion system protein E	pilB	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N,cNMP_binding
CMS1_k127_4022488_3	1150469.RSPPHO_02023	4.056e-151	494.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,2TR0F@28211|Alphaproteobacteria,2JPYH@204441|Rhodospirillales	204441|Rhodospirillales	EH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
CMS1_k127_4022488_1	665571.STHERM_c18430	1.928e-173	553.0	COG0538@1|root,COG0538@2|Bacteria,2J5RP@203691|Spirochaetes	203691|Spirochaetes	C	PFAM isocitrate isopropylmalate dehydrogenase	-	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
CMS1_k127_4022488_11	596151.DesfrDRAFT_3630	5.411e-25	115.0	COG4191@1|root,COG4191@2|Bacteria,1P0U1@1224|Proteobacteria,42PTP@68525|delta/epsilon subdivisions,2WJ8U@28221|Deltaproteobacteria,2M8NY@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
CMS1_k127_4022488_13	545695.TREAZ_0858	7.391e-13	79.0	COG2227@1|root,COG2227@2|Bacteria,2J6CB@203691|Spirochaetes	203691|Spirochaetes	H	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
CMS1_k127_4022488_4	880072.Desac_2864	6.41e-76	266.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,42NYX@68525|delta/epsilon subdivisions,2WJV8@28221|Deltaproteobacteria,2MQEX@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	arnC	-	2.4.2.53	ko:K10012,ko:K20534	ko00520,ko01503,map00520,map01503	M00721,M00761	R07661	RC00005,RC02954	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	4.D.2.1.8,4.D.2.1.9	GT2	-	Glycos_transf_2
CMS1_k127_4022488_5	452662.SJA_C1-34700	2.76e-61	225.0	COG0458@1|root,COG0458@2|Bacteria,1RJ88@1224|Proteobacteria,2UB8A@28211|Alphaproteobacteria,2KDET@204457|Sphingomonadales	204457|Sphingomonadales	EF	carbamoylphosphate synthase large subunit (split gene in MJ)	-	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_3
CMS1_k127_4022488_6	483218.BACPEC_03197	1.237e-55	205.0	COG0451@1|root,COG0451@2|Bacteria,1UKPS@1239|Firmicutes,24T4N@186801|Clostridia	186801|Clostridia	M	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
CMS1_k127_4022488_0	96561.Dole_2465	8.847e-181	593.0	COG0399@1|root,COG0451@1|root,COG0399@2|Bacteria,COG0451@2|Bacteria,1MUPN@1224|Proteobacteria,42MTX@68525|delta/epsilon subdivisions,2WITE@28221|Deltaproteobacteria,2MIIQ@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	arnB	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
CMS1_k127_4022488_10	1210884.HG799464_gene10614	6.06e-42	162.0	COG0745@1|root,COG0745@2|Bacteria,2IY82@203682|Planctomycetes	203682|Planctomycetes	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17,Response_reg
CMS1_k127_4022488_8	459495.SPLC1_S101730	2.213e-49	184.0	COG0317@1|root,COG0317@2|Bacteria,1G0F8@1117|Cyanobacteria,1HA1X@1150|Oscillatoriales	1117|Cyanobacteria	KT	PFAM Metal-dependent phosphohydrolase, HD	-	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	HD_4
CMS1_k127_4022488_7	935948.KE386494_gene413	1.493e-53	192.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,42F3H@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM ABC transporter related	msmX	-	3.6.3.20	ko:K05816,ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00198,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.1,3.A.1.1.3	-	-	ABC_tran,TOBE,TOBE_2
CMS1_k127_4025130_2	1340493.JNIF01000003_gene4296	9.537e-07	55.0	2DZRA@1|root,32VGT@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
CMS1_k127_4025130_0	180332.JTGN01000009_gene4222	5.99e-115	378.0	COG0407@1|root,COG0407@2|Bacteria,1V3M9@1239|Firmicutes,25AY7@186801|Clostridia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
CMS1_k127_4025130_1	234267.Acid_5505	3.089e-35	141.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS1_k127_4039112_2	357808.RoseRS_3136	3.108e-85	302.0	COG0419@1|root,COG0419@2|Bacteria	2|Bacteria	L	ATPase involved in DNA repair	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	AAA_13,AAA_23,Kelch_1,Kelch_4,Peptidase_C14,Tubulin_2,WD40
CMS1_k127_4039112_0	357808.RoseRS_3135	6.098e-158	527.0	COG3540@1|root,COG3540@2|Bacteria,2G9SZ@200795|Chloroflexi	200795|Chloroflexi	P	Alkaline phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4039112_1	1366050.N234_09810	7.197e-137	449.0	28H5N@1|root,2Z7I8@2|Bacteria,1RC6E@1224|Proteobacteria,2W05M@28216|Betaproteobacteria,1KENA@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4046050_0	1382306.JNIM01000001_gene3484	1.174e-204	648.0	COG0365@1|root,COG0365@2|Bacteria	2|Bacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	badA	-	6.2.1.25,6.2.1.27	ko:K04105,ko:K04110	ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220	-	R01300,R01422	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
CMS1_k127_4046050_3	1123322.KB904680_gene3404	3.756e-51	200.0	COG1232@1|root,COG1232@2|Bacteria,2IEDS@201174|Actinobacteria	201174|Actinobacteria	H	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
CMS1_k127_4046050_1	1049564.TevJSym_ah00010	5.835e-112	368.0	COG3291@1|root,COG3868@1|root,COG4257@1|root,COG4409@1|root,COG3291@2|Bacteria,COG3868@2|Bacteria,COG4257@2|Bacteria,COG4409@2|Bacteria,1QWZ9@1224|Proteobacteria,1T30T@1236|Gammaproteobacteria,1JAP8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Cellulase N-terminal ig-like domain	cel9A	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_10,CBM_2,CelD_N,Glyco_hydro_9,PKD
CMS1_k127_4046050_4	675635.Psed_3881	6.974e-30	138.0	COG3420@1|root,COG3420@2|Bacteria,2I0IB@201174|Actinobacteria,4E1TX@85010|Pseudonocardiales	2|Bacteria	P	Periplasmic copper-binding protein (NosD)	-	-	-	ko:K07218	-	-	-	-	ko00000	-	-	-	Beta_helix,NosD
CMS1_k127_4046050_2	1223523.H340_12652	1.172e-69	263.0	COG0823@1|root,COG0823@2|Bacteria,2GMNT@201174|Actinobacteria	201174|Actinobacteria	U	Periplasmic component of the Tol biopolymer transport system	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
CMS1_k127_4048114_3	251221.35213742	1.134e-102	349.0	COG1228@1|root,COG1228@2|Bacteria	2|Bacteria	Q	imidazolonepropionase activity	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
CMS1_k127_4048114_15	321327.CYA_0238	2.268e-32	137.0	COG0500@1|root,COG0500@2|Bacteria,1G9T2@1117|Cyanobacteria,1H1AQ@1129|Synechococcus	1117|Cyanobacteria	Q	similarity to GB CAH39666.1	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
CMS1_k127_4048114_9	1121481.AUAS01000005_gene2089	3.21e-56	212.0	COG2942@1|root,COG2942@2|Bacteria,4NHTQ@976|Bacteroidetes,47KVQ@768503|Cytophagia	976|Bacteroidetes	G	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)	-	-	5.1.3.11	ko:K16213	-	-	R01445,R10810	RC00289	ko00000,ko01000	-	-	-	GlcNAc_2-epim
CMS1_k127_4048114_10	760568.Desku_0639	1.707e-55	199.0	COG0290@1|root,COG0290@2|Bacteria,1V1RC@1239|Firmicutes,24FUS@186801|Clostridia,260V8@186807|Peptococcaceae	186801|Clostridia	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
CMS1_k127_4048114_17	743299.Acife_2537	9.902e-12	69.0	COG0291@1|root,COG0291@2|Bacteria,1N6V4@1224|Proteobacteria,1SCHI@1236|Gammaproteobacteria,2ND98@225057|Acidithiobacillales	225057|Acidithiobacillales	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
CMS1_k127_4048114_14	1033739.CAEU01000018_gene2311	1.875e-36	143.0	COG0292@1|root,COG0292@2|Bacteria,1V6DB@1239|Firmicutes,4HH2W@91061|Bacilli,26F6B@186818|Planococcaceae	91061|Bacilli	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
CMS1_k127_4048114_4	398767.Glov_1019	2.073e-68	240.0	COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,42NRX@68525|delta/epsilon subdivisions,2WK1K@28221|Deltaproteobacteria,43SU7@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	TIGRFAM phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0388	His_biosynth
CMS1_k127_4048114_11	530564.Psta_1058	6.47e-55	203.0	COG0287@1|root,COG0287@2|Bacteria,2IZ5K@203682|Planctomycetes	203682|Planctomycetes	E	Prephenate dehydrogenase	-	-	1.3.1.12,1.3.1.43	ko:K00210,ko:K00220,ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025,M00040	R00732,R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
CMS1_k127_4048114_7	1157490.EL26_20400	1.249e-60	216.0	COG0125@1|root,COG0125@2|Bacteria,1V1HE@1239|Firmicutes,4HGWR@91061|Bacilli,278BR@186823|Alicyclobacillaceae	91061|Bacilli	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS02535	Thymidylate_kin
CMS1_k127_4048114_13	574087.Acear_0044	1.687e-46	182.0	COG2812@1|root,COG2812@2|Bacteria,1VCQC@1239|Firmicutes,248U4@186801|Clostridia,3WAJV@53433|Halanaerobiales	186801|Clostridia	L	TIGRFAM DNA polymerase III, delta	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
CMS1_k127_4048114_6	477974.Daud_0038	1.676e-64	233.0	COG1774@1|root,COG1774@2|Bacteria,1TP1V@1239|Firmicutes,247Q6@186801|Clostridia,260CA@186807|Peptococcaceae	186801|Clostridia	S	pfam psp1	yaaT	-	-	-	-	-	-	-	-	-	-	-	PSP1
CMS1_k127_4048114_5	338963.Pcar_1695	3.995e-68	242.0	COG0084@1|root,COG0535@1|root,COG0084@2|Bacteria,COG0535@2|Bacteria,1MUC0@1224|Proteobacteria,42MMS@68525|delta/epsilon subdivisions,2WMUI@28221|Deltaproteobacteria,43S50@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	TatD related DNase	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_14,Radical_SAM,TatD_DNase
CMS1_k127_4048114_1	1128421.JAGA01000002_gene1587	1.828e-153	509.0	COG0115@1|root,COG0147@1|root,COG0115@2|Bacteria,COG0147@2|Bacteria,2NP4C@2323|unclassified Bacteria	2|Bacteria	EH	chorismate binding enzyme	pabB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.6.1.85,4.1.3.27,4.1.3.38	ko:K01665,ko:K02619,ko:K03342,ko:K13503,ko:K13950	ko00400,ko00790,ko01100,ko01110,ko01130,ko01230,map00400,map00790,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01716,R05553	RC00010,RC01418,RC01843,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4,Anth_synt_I_N,Chorismate_bind
CMS1_k127_4048114_0	886293.Sinac_6095	4.853e-236	752.0	COG1073@1|root,COG1073@2|Bacteria,2IYEI@203682|Planctomycetes	203682|Planctomycetes	Q	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	DLH
CMS1_k127_4048114_2	1379270.AUXF01000002_gene1518	2.214e-141	459.0	COG2355@1|root,COG2355@2|Bacteria,1ZUCR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	Membrane dipeptidase (Peptidase family M19)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M19
CMS1_k127_4048114_12	765420.OSCT_1823	7.397e-54	209.0	2E0CW@1|root,32VZR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4048114_8	316067.Geob_0827	8.254e-60	227.0	COG1295@1|root,COG1959@1|root,COG1295@2|Bacteria,COG1959@2|Bacteria,1QICW@1224|Proteobacteria,42MBW@68525|delta/epsilon subdivisions,2WK2Z@28221|Deltaproteobacteria,43SWT@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	PFAM ribonuclease BN	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Rrf2,Virul_fac_BrkB
CMS1_k127_4048130_11	1121481.AUAS01000004_gene1480	1.434e-19	100.0	COG3291@1|root,COG4733@1|root,COG3291@2|Bacteria,COG4733@2|Bacteria,4PKMJ@976|Bacteroidetes	2|Bacteria	G	Cellulase N-terminal ig-like domain	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	Big_2,CHU_C,GSDH,Laminin_G_3,PKD,fn3
CMS1_k127_4048130_7	472759.Nhal_1223	2.287e-58	224.0	COG1716@1|root,COG2203@1|root,COG2208@1|root,COG1716@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,1MXJQ@1224|Proteobacteria,1RQIY@1236|Gammaproteobacteria,1WXGP@135613|Chromatiales	135613|Chromatiales	KT	PFAM Stage II sporulation E family protein	-	-	3.1.3.3	ko:K01079,ko:K07315	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03021	-	-	-	GAF,HAMP,SpoIIE,dCache_1
CMS1_k127_4048130_16	1265505.ATUG01000001_gene3110	2.901e-14	86.0	COG2172@1|root,COG2172@2|Bacteria,1Q2UT@1224|Proteobacteria,42V6B@68525|delta/epsilon subdivisions,2WRJ9@28221|Deltaproteobacteria,2MKWV@213118|Desulfobacterales	28221|Deltaproteobacteria	T	anti-sigma regulatory factor	-	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
CMS1_k127_4048130_14	314345.SPV1_11916	4.36e-15	79.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
CMS1_k127_4048130_4	1499967.BAYZ01000135_gene84	1.343e-71	251.0	COG0767@1|root,COG0767@2|Bacteria,2NPFZ@2323|unclassified Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents permease component	mlaE_1	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE,STAS_2
CMS1_k127_4048130_1	1499967.BAYZ01000135_gene85	1.927e-97	325.0	COG1127@1|root,COG1127@2|Bacteria,2NP3U@2323|unclassified Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, ATPase component	ttg2A	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
CMS1_k127_4048130_15	1313265.JNIE01000003_gene1212	1.151e-14	85.0	COG1463@1|root,COG1463@2|Bacteria,2G3I1@200783|Aquificae	200783|Aquificae	Q	Mammalian cell entry related domain protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
CMS1_k127_4048130_18	1120973.AQXL01000098_gene888	0.0001718	51.0	COG5581@1|root,COG5581@2|Bacteria,1U2DE@1239|Firmicutes,4IBZ4@91061|Bacilli,27A8E@186823|Alicyclobacillaceae	91061|Bacilli	M	Flagellar protein YcgR	-	-	-	-	-	-	-	-	-	-	-	-	PilZ,YcgR_2
CMS1_k127_4048130_6	1121920.AUAU01000004_gene773	4.751e-64	242.0	COG0860@1|root,COG0860@2|Bacteria	2|Bacteria	M	N-Acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01448,ko:K02172	ko01501,ko01503,map01501,map01503	M00627,M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko03036	-	-	-	Amidase_3,Cu_amine_oxidN1
CMS1_k127_4048130_5	344747.PM8797T_26195	4.982e-65	229.0	COG3762@1|root,COG3762@2|Bacteria	2|Bacteria	S	Membrane	Z012_08985	-	-	ko:K08988	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
CMS1_k127_4048130_2	344747.PM8797T_26200	2.003e-88	299.0	COG1512@1|root,COG1512@2|Bacteria,2J44M@203682|Planctomycetes	203682|Planctomycetes	S	TPM domain	-	-	-	-	-	-	-	-	-	-	-	-	TPM_phosphatase
CMS1_k127_4048130_0	1303518.CCALI_00708	3.489e-141	482.0	COG3408@1|root,COG3408@2|Bacteria	2|Bacteria	G	Glycogen debranching enzyme	-	-	3.2.1.187	ko:K18206	-	-	-	-	ko00000,ko01000	-	GH121	-	Big_4,F5_F8_type_C,FIVAR,Laminin_G_3,SLH
CMS1_k127_4048130_8	926560.KE387023_gene3415	6.492e-46	169.0	COG0454@1|root,COG0454@2|Bacteria,1WMP9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
CMS1_k127_4048130_10	574087.Acear_1438	4.256e-31	132.0	28NSZ@1|root,2ZBRT@2|Bacteria,1V8T4@1239|Firmicutes,24JQ5@186801|Clostridia,3WBT7@53433|Halanaerobiales	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4048130_9	858215.Thexy_2211	3.521e-44	185.0	COG4354@1|root,COG4354@2|Bacteria,1TR78@1239|Firmicutes,25K1B@186801|Clostridia,42ITY@68295|Thermoanaerobacterales	186801|Clostridia	G	beta-glucosidase 2, glycosyl-hydrolase family 116 N-term	-	-	3.2.1.45	ko:K17108	ko00511,ko00600,ko01100,map00511,map00600,map01100	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH116	-	DUF608,Glyco_hydr_116N
CMS1_k127_4048130_12	1121346.KB899826_gene406	3.197e-17	92.0	COG0596@1|root,COG0596@2|Bacteria,1UI50@1239|Firmicutes,4ISDP@91061|Bacilli,2772B@186822|Paenibacillaceae	91061|Bacilli	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CMS1_k127_4048130_13	247490.KSU1_C1333	5.876e-16	89.0	COG4968@1|root,COG4968@2|Bacteria,2J519@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CMS1_k127_4048130_3	509635.N824_05290	1.711e-80	279.0	COG1082@1|root,COG1082@2|Bacteria,4NEUS@976|Bacteroidetes,1ITFA@117747|Sphingobacteriia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS1_k127_4048130_17	1123284.KB899043_gene130	2.542e-12	79.0	COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,4HB0C@91061|Bacilli,26NHY@186821|Sporolactobacillaceae	91061|Bacilli	NU	Type II secretion system (T2SS), protein E, N-terminal domain	pilB	-	-	ko:K02243,ko:K02652	-	M00429	-	-	ko00000,ko00002,ko02035,ko02044	3.A.14.1,3.A.15.2	-	-	T2SSE,T2SSE_N
CMS1_k127_4061117_1	1189612.A33Q_4676	8.418e-99	333.0	COG4409@1|root,COG4692@1|root,COG4409@2|Bacteria,COG4692@2|Bacteria,4NE1P@976|Bacteroidetes,47TDC@768503|Cytophagia	976|Bacteroidetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
CMS1_k127_4061117_0	477974.Daud_1110	2.041e-118	396.0	COG2262@1|root,COG2262@2|Bacteria,1TNZB@1239|Firmicutes,248IU@186801|Clostridia,2606G@186807|Peptococcaceae	186801|Clostridia	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
CMS1_k127_4061117_2	572544.Ilyop_0684	6.431e-32	132.0	COG1051@1|root,COG1051@2|Bacteria,37ASE@32066|Fusobacteria	32066|Fusobacteria	F	Hydrolase, NUDIX family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS1_k127_4061117_3	1304885.AUEY01000003_gene458	2.731e-09	64.0	2971T@1|root,2ZUA7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4062411_4	344747.PM8797T_10954	2.394e-76	260.0	COG0673@1|root,COG0673@2|Bacteria,2IWX9@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_4062411_2	1120950.KB892746_gene3438	1.88e-105	378.0	29XIB@1|root,30J98@2|Bacteria,2H3UJ@201174|Actinobacteria	201174|Actinobacteria	S	Heparinase II/III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III
CMS1_k127_4062411_1	234267.Acid_4736	7.499e-130	436.0	COG0457@1|root,COG0457@2|Bacteria,3Y3RA@57723|Acidobacteria	57723|Acidobacteria	M	SMART Tetratricopeptide	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
CMS1_k127_4062411_3	616991.JPOO01000003_gene2394	1.152e-85	309.0	COG1262@1|root,COG1262@2|Bacteria,4NGBN@976|Bacteroidetes	976|Bacteroidetes	S	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
CMS1_k127_4062411_0	616991.JPOO01000003_gene2393	4.777e-140	469.0	COG3292@1|root,COG3292@2|Bacteria,4P1XS@976|Bacteroidetes	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4063245_5	69319.XP_008556961.1	1.734e-21	105.0	COG0666@1|root,KOG0504@2759|Eukaryota,39YNX@33154|Opisthokonta,3BFJC@33208|Metazoa,3CU3G@33213|Bilateria,41W8R@6656|Arthropoda,3SG48@50557|Insecta,46EVN@7399|Hymenoptera	33208|Metazoa	S	Ankyrin repeat	ANKRD50	GO:0006810,GO:0008150,GO:0016192,GO:0016197,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0098876,GO:1990126	-	ko:K21440	-	-	-	-	ko00000,ko04131	-	-	-	Ank,Ank_2,Ank_4
CMS1_k127_4063245_4	1123508.JH636439_gene737	1.584e-34	143.0	COG1409@1|root,COG1409@2|Bacteria	1123508.JH636439_gene737|-	S	acid phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4063245_0	1089550.ATTH01000001_gene1363	7.192e-218	689.0	COG4146@1|root,COG4146@2|Bacteria,4NE9S@976|Bacteroidetes,1FJZQ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
CMS1_k127_4063245_1	518766.Rmar_0424	4.892e-166	541.0	COG0025@1|root,COG0569@1|root,COG1762@1|root,COG0025@2|Bacteria,COG0569@2|Bacteria,COG1762@2|Bacteria,4PKJ5@976|Bacteroidetes,1FIVS@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,TrkA_N
CMS1_k127_4063245_3	243231.GSU1748	1.179e-62	230.0	COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,42ME9@68525|delta/epsilon subdivisions,2WKF0@28221|Deltaproteobacteria,43U10@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
CMS1_k127_4063245_2	1499967.BAYZ01000026_gene1631	1.594e-87	304.0	COG0367@1|root,COG0367@2|Bacteria,2NNKE@2323|unclassified Bacteria	2|Bacteria	E	PFAM asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
CMS1_k127_4063273_0	370438.PTH_1367	2.039e-114	377.0	COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,248DH@186801|Clostridia,260EM@186807|Peptococcaceae	186801|Clostridia	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.27,1.1.1.37	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R00703,R01000,R03104,R07136	RC00031,RC00044	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
CMS1_k127_4063273_2	743720.Psefu_0203	1.11e-33	145.0	COG2823@1|root,COG2823@2|Bacteria,1PY9S@1224|Proteobacteria,1SWT7@1236|Gammaproteobacteria,1YX4H@136845|Pseudomonas putida group	1236|Gammaproteobacteria	S	SMART Transport-associated and nodulation	-	-	-	-	-	-	-	-	-	-	-	-	BON
CMS1_k127_4063273_1	504472.Slin_6606	4.033e-86	293.0	COG3836@1|root,COG3836@2|Bacteria,4NJ5Y@976|Bacteroidetes,47NC8@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the HpcH HpaI aldolase family	-	-	4.1.2.52	ko:K02510	ko00350,ko01120,map00350,map01120	-	R01645,R01647	RC00307,RC00572,RC00574,RC03057	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
CMS1_k127_4064573_4	1121472.AQWN01000006_gene1668	3.652e-111	383.0	COG0247@1|root,COG1139@1|root,COG0247@2|Bacteria,COG1139@2|Bacteria,1TREQ@1239|Firmicutes,24BXS@186801|Clostridia,260MC@186807|Peptococcaceae	186801|Clostridia	C	Uncharacterised ACR, YkgG family COG1556	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8,LUD_dom
CMS1_k127_4064573_11	1128421.JAGA01000003_gene3368	1.815e-17	92.0	COG1556@1|root,COG1556@2|Bacteria,2NRWC@2323|unclassified Bacteria	2|Bacteria	S	LUD domain	-	-	-	ko:K00782,ko:K18929	-	-	-	-	ko00000	-	-	-	LUD_dom
CMS1_k127_4064573_9	478741.JAFS01000002_gene956	3.81e-54	197.0	COG1403@1|root,COG1403@2|Bacteria,46SMP@74201|Verrucomicrobia,37GDF@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	L	HNH endonuclease	mcrA	-	-	-	-	-	-	-	-	-	-	-	HNH_5
CMS1_k127_4064573_1	1340493.JNIF01000004_gene1012	1.144e-183	602.0	COG1198@1|root,COG1198@2|Bacteria,3Y2NY@57723|Acidobacteria	57723|Acidobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
CMS1_k127_4064573_14	1353531.AZNX01000006_gene5467	6.818e-11	74.0	COG0745@1|root,COG0784@1|root,COG5002@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,2TW1J@28211|Alphaproteobacteria,4B7HQ@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HAMP,HATPase_c,HisKA,PAS_7,Response_reg
CMS1_k127_4064573_7	316067.Geob_1497	3.784e-70	247.0	COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,42P3I@68525|delta/epsilon subdivisions,2WM37@28221|Deltaproteobacteria,43TDJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
CMS1_k127_4064573_0	1125863.JAFN01000001_gene353	0.0	1413.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,42MGK@68525|delta/epsilon subdivisions,2WJQH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
CMS1_k127_4064573_10	880073.Calab_0004	2.217e-30	128.0	COG0782@1|root,COG0782@2|Bacteria,2NPT2@2323|unclassified Bacteria	2|Bacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
CMS1_k127_4064573_13	762966.HMPREF9439_00091	4.766e-15	86.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,2VIQ4@28216|Betaproteobacteria,4PQGA@995019|Sutterellaceae	28216|Betaproteobacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
CMS1_k127_4064573_3	1089551.KE386572_gene521	6.368e-125	430.0	COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,2TQJV@28211|Alphaproteobacteria,4BR8I@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	G	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K10562	ko02010,map02010	M00220	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.9	-	-	ABC_tran
CMS1_k127_4064573_8	314231.FP2506_11957	4.414e-57	224.0	COG1172@1|root,COG1172@2|Bacteria,1MV4F@1224|Proteobacteria,2TT2T@28211|Alphaproteobacteria,2PKCZ@255475|Aurantimonadaceae	28211|Alphaproteobacteria	P	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10561	ko02010,map02010	M00220	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.9	-	-	BPD_transp_2
CMS1_k127_4064573_5	266117.Rxyl_1681	4.329e-96	327.0	COG1879@1|root,COG1879@2|Bacteria,2I43Z@201174|Actinobacteria,4CPWY@84995|Rubrobacteria	84995|Rubrobacteria	G	Periplasmic binding protein domain	-	-	-	ko:K10559	ko02010,map02010	M00220	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.9	-	-	Peripla_BP_4
CMS1_k127_4064573_12	316067.Geob_3734	1.861e-16	88.0	COG0613@1|root,COG0613@2|Bacteria,1NFVB@1224|Proteobacteria,43BBY@68525|delta/epsilon subdivisions,2X6R1@28221|Deltaproteobacteria,43VUU@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PHP domain protein	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	APH,DUF2889,PHP_C
CMS1_k127_4064573_6	1120950.KB892747_gene3702	2.921e-77	282.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	GxGYxYP_C,GxGYxYP_N
CMS1_k127_4064573_2	1511.CLOST_0922	3.522e-170	541.0	COG0205@1|root,COG0205@2|Bacteria,1TRJQ@1239|Firmicutes,247IV@186801|Clostridia	186801|Clostridia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
CMS1_k127_4070154_2	1541959.KQ51_00391	1.313e-08	57.0	COG0230@1|root,COG0230@2|Bacteria	2|Bacteria	J	Ribosomal protein L34	rpmH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
CMS1_k127_4070154_0	452637.Oter_3517	9.242e-63	235.0	COG0793@1|root,COG0793@2|Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
CMS1_k127_4070154_1	215803.DB30_7179	6.586e-12	66.0	COG1770@1|root,COG1770@2|Bacteria,1MUED@1224|Proteobacteria,42YQP@68525|delta/epsilon subdivisions,2WTJM@28221|Deltaproteobacteria,2YY5X@29|Myxococcales	28221|Deltaproteobacteria	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
CMS1_k127_4077881_5	1128421.JAGA01000003_gene3369	4.76e-38	149.0	COG0673@1|root,COG0673@2|Bacteria,2NP86@2323|unclassified Bacteria	2|Bacteria	C	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_4077881_8	261292.Nit79A3_0706	0.000633	51.0	COG2199@1|root,COG3706@2|Bacteria,1PWAZ@1224|Proteobacteria,2WBVM@28216|Betaproteobacteria,373VZ@32003|Nitrosomonadales	28216|Betaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
CMS1_k127_4077881_6	1121396.KB892913_gene149	3.801e-34	145.0	COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42RC2@68525|delta/epsilon subdivisions,2X8JD@28221|Deltaproteobacteria,2MJQ0@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	PAS_9
CMS1_k127_4077881_1	1403819.BATR01000118_gene4166	3.278e-106	354.0	COG0332@1|root,COG0332@2|Bacteria,46SE2@74201|Verrucomicrobia,2ITMR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
CMS1_k127_4077881_4	929556.Solca_1355	2.545e-47	175.0	COG0662@1|root,COG0662@2|Bacteria,4NQIP@976|Bacteroidetes,1IZZH@117747|Sphingobacteriia	976|Bacteroidetes	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS1_k127_4077881_3	886293.Sinac_4789	6.858e-59	211.0	COG0386@1|root,COG0386@2|Bacteria,2IZ7Z@203682|Planctomycetes	203682|Planctomycetes	O	Belongs to the glutathione peroxidase family	-	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
CMS1_k127_4077881_0	1123242.JH636435_gene2066	9.875e-244	776.0	COG2366@1|root,COG2366@2|Bacteria,2J08A@203682|Planctomycetes	203682|Planctomycetes	S	Penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
CMS1_k127_4077881_7	326427.Cagg_0714	6.144e-14	84.0	COG2334@1|root,COG2334@2|Bacteria,2G9QM@200795|Chloroflexi,3762I@32061|Chloroflexia	32061|Chloroflexia	S	PFAM aminoglycoside phosphotransferase	-	-	2.7.1.39	ko:K02204	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	APH
CMS1_k127_4077881_2	880070.Cycma_3753	8.958e-91	309.0	COG0667@1|root,COG0667@2|Bacteria,4NEB0@976|Bacteroidetes,47XEA@768503|Cytophagia	976|Bacteroidetes	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS1_k127_4083631_2	234267.Acid_2426	0.0006291	42.0	COG5588@1|root,COG5588@2|Bacteria,3Y7RN@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF1326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1326
CMS1_k127_4083631_1	204669.Acid345_0766	1.226e-09	70.0	2E6AH@1|root,330YD@2|Bacteria,3Y8MQ@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4083631_0	1123242.JH636436_gene156	8.003e-48	183.0	2AU2S@1|root,31JP5@2|Bacteria,2IZEE@203682|Planctomycetes	203682|Planctomycetes	S	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CMS1_k127_4102697_4	313628.LNTAR_21235	1.199e-18	93.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CMS1_k127_4102697_3	545696.HOLDEFILI_00247	7.976e-25	114.0	COG0327@1|root,COG0327@2|Bacteria,1V7R4@1239|Firmicutes,3VQSZ@526524|Erysipelotrichia	526524|Erysipelotrichia	S	NIF3 (NGG1p interacting factor 3)	-	-	-	-	-	-	-	-	-	-	-	-	NIF3
CMS1_k127_4102697_2	1128421.JAGA01000001_gene2102	2.66e-36	149.0	COG3828@1|root,COG3828@2|Bacteria	2|Bacteria	N	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
CMS1_k127_4102697_1	180332.JTGN01000025_gene1535	2.371e-76	274.0	COG3119@1|root,COG3119@2|Bacteria,1TQEP@1239|Firmicutes,2482B@186801|Clostridia	186801|Clostridia	P	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS1_k127_4102697_0	525904.Tter_0528	2.147e-183	586.0	COG3119@1|root,COG3119@2|Bacteria,2NR0Q@2323|unclassified Bacteria	2|Bacteria	P	Sulfatase	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_tranf_2_3,Glycos_transf_2,Sulfatase
CMS1_k127_4114915_1	1121271.AUCM01000002_gene4126	3.832e-18	87.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2TR6Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Belongs to the DEAD box helicase family	rhlE	-	3.6.4.13	ko:K03732,ko:K11927	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03019	-	-	-	DEAD,Helicase_C
CMS1_k127_4114915_0	1267535.KB906767_gene2380	1.16e-99	331.0	COG5285@1|root,COG5285@2|Bacteria	2|Bacteria	Q	dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
CMS1_k127_4114915_2	247490.KSU1_D0372	1.673e-14	82.0	COG1033@1|root,COG1033@2|Bacteria,2IYET@203682|Planctomycetes	203682|Planctomycetes	S	of the RND superfamily	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
CMS1_k127_4120179_4	742159.HMPREF0004_4148	2.405e-80	273.0	COG0765@1|root,COG0765@2|Bacteria,1R3X2@1224|Proteobacteria,2W1TR@28216|Betaproteobacteria,3T27W@506|Alcaligenaceae	28216|Betaproteobacteria	E	ABC transporter permease	ehuC	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
CMS1_k127_4120179_3	1392838.AWNM01000071_gene665	2.891e-83	289.0	COG0765@1|root,COG0765@2|Bacteria,1MWF0@1224|Proteobacteria,2VM04@28216|Betaproteobacteria,3T1CU@506|Alcaligenaceae	28216|Betaproteobacteria	E	ABC-type amino acid transport system permease component	ehuD	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
CMS1_k127_4120179_0	1134413.ANNK01000046_gene1060	4.103e-101	340.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli,1ZB2E@1386|Bacillus	91061|Bacilli	E	COG1126 ABC-type polar amino acid transport system, ATPase component	-	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
CMS1_k127_4120179_5	234267.Acid_2488	3.788e-70	245.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS1_k127_4120179_1	1156937.MFUM_170030	4.157e-93	321.0	COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,46TM8@74201|Verrucomicrobia,37G70@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	C	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K07305,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
CMS1_k127_4120179_2	530564.Psta_3957	4.245e-85	291.0	COG1793@1|root,COG1793@2|Bacteria,2IYJZ@203682|Planctomycetes	203682|Planctomycetes	L	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CMS1_k127_4120179_6	313603.FB2170_10661	2.135e-41	163.0	COG0673@1|root,COG0673@2|Bacteria,4NGHJ@976|Bacteroidetes,1HZS8@117743|Flavobacteriia	976|Bacteroidetes	S	Pfam Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_4120221_0	909663.KI867150_gene1437	3.515e-257	797.0	COG1156@1|root,COG1156@2|Bacteria,1R4RB@1224|Proteobacteria,42PJC@68525|delta/epsilon subdivisions,2WJB9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	-	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
CMS1_k127_4120221_3	909663.KI867150_gene1438	6.323e-81	279.0	COG1394@1|root,COG1394@2|Bacteria,1PA1A@1224|Proteobacteria,42VQ3@68525|delta/epsilon subdivisions,2WT1Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	-	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
CMS1_k127_4120221_7	517418.Ctha_2358	6.542e-21	98.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,GGDEF,Response_reg
CMS1_k127_4120221_2	1283300.ATXB01000001_gene2344	2.637e-87	298.0	COG1215@1|root,COG1215@2|Bacteria,1QVG6@1224|Proteobacteria	1224|Proteobacteria	M	COG0463 Glycosyltransferases involved in cell wall biogenesis	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
CMS1_k127_4120221_6	290397.Adeh_1534	2.619e-44	164.0	COG1146@1|root,COG1146@2|Bacteria,1RH5I@1224|Proteobacteria,43C2Q@68525|delta/epsilon subdivisions,2WSJ0@28221|Deltaproteobacteria,2YVH1@29|Myxococcales	28221|Deltaproteobacteria	C	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions	-	-	-	ko:K05524	-	-	-	-	ko00000	-	-	-	DUF3470,Fer4
CMS1_k127_4120221_4	1293047.CBMA010000014_gene829	2.779e-63	229.0	COG0189@1|root,arCOG01589@2157|Archaea,2Y425@28890|Euryarchaeota,23ZSF@183963|Halobacteria	183963|Halobacteria	H	Prokaryotic glutathione synthetase, ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	RimK
CMS1_k127_4120221_8	583355.Caka_1926	6.675e-18	91.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB,DinB_2
CMS1_k127_4120221_9	1408433.JHXV01000008_gene61	1.657e-06	59.0	COG3332@1|root,COG3332@2|Bacteria,4NMN7@976|Bacteroidetes,1I1KH@117743|Flavobacteriia,2PBZ0@246874|Cryomorphaceae	976|Bacteroidetes	S	Transport and Golgi organisation 2	-	-	-	-	-	-	-	-	-	-	-	-	TANGO2
CMS1_k127_4120221_1	1210884.HG799463_gene9621	3.536e-92	323.0	COG0189@1|root,COG0586@1|root,COG3332@1|root,COG0189@2|Bacteria,COG0586@2|Bacteria,COG3332@2|Bacteria	2|Bacteria	S	Transport and Golgi organisation 2	-	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	RimK,SNARE_assoc,TANGO2
CMS1_k127_4120221_5	1089550.ATTH01000001_gene2217	1.46e-47	181.0	COG3176@1|root,COG3176@2|Bacteria,4PKEK@976|Bacteroidetes	976|Bacteroidetes	S	hemolysin	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5
CMS1_k127_4132203_0	1123508.JH636439_gene1210	3.435e-150	488.0	COG3119@1|root,COG3119@2|Bacteria,2IX69@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS1_k127_4132203_1	1122994.AUFR01000001_gene1431	2.799e-27	119.0	COG1595@1|root,COG1595@2|Bacteria,2GJ02@201174|Actinobacteria,4DMYC@85009|Propionibacteriales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigH	GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_4132203_2	1304885.AUEY01000078_gene1052	5.551e-26	120.0	COG0500@1|root,COG2226@2|Bacteria,1R2WX@1224|Proteobacteria,42QTU@68525|delta/epsilon subdivisions,2X8NZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4136615_3	113355.CM001775_gene1259	3.464e-05	53.0	COG1216@1|root,COG1216@2|Bacteria,1G1PB@1117|Cyanobacteria	1117|Cyanobacteria	S	Glycosyl transferase, family 2	wcaA	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS1_k127_4136615_0	411467.BACCAP_00497	8.543e-52	199.0	COG0420@1|root,COG0420@2|Bacteria,1TWMI@1239|Firmicutes,24BN3@186801|Clostridia,268PV@186813|unclassified Clostridiales	186801|Clostridia	L	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,Metallophos_2
CMS1_k127_4136615_1	997346.HMPREF9374_1655	6.217e-36	159.0	COG0419@1|root,COG0419@2|Bacteria,1UI2P@1239|Firmicutes,4IC74@91061|Bacilli,27CUD@186824|Thermoactinomycetaceae	91061|Bacilli	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_23
CMS1_k127_4136615_2	1123248.KB893317_gene4292	3.018e-09	58.0	COG0613@1|root,COG0613@2|Bacteria,4PN3D@976|Bacteroidetes	976|Bacteroidetes	S	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4153511_2	1444309.JAQG01000087_gene2658	1.826e-19	93.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,4HA6M@91061|Bacilli,26T10@186822|Paenibacillaceae	91061|Bacilli	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA_1	-	2.1.1.190,2.1.1.35	ko:K00557,ko:K03215	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	TRAM,tRNA_U5-meth_tr
CMS1_k127_4153511_4	1187851.A33M_4395	2.994e-15	78.0	2BUZT@1|root,32QCC@2|Bacteria,1Q8TE@1224|Proteobacteria,2UYDE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4153511_0	1187851.A33M_4394	5.97e-53	191.0	COG1848@1|root,COG1848@2|Bacteria,1RK9K@1224|Proteobacteria	1224|Proteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
CMS1_k127_4153511_1	1297570.MESS4_310098	9.992e-25	105.0	COG2189@1|root,COG2189@2|Bacteria,1MX9M@1224|Proteobacteria,2TRE4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	dna methylase	-	-	2.1.1.72	ko:K00571,ko:K07316	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Mrr_cat,N6_N4_Mtase
CMS1_k127_4153511_3	562970.Btus_2240	5.656e-17	91.0	COG1396@1|root,COG2856@1|root,COG1396@2|Bacteria,COG2856@2|Bacteria,1TQAC@1239|Firmicutes,4HJ3C@91061|Bacilli	91061|Bacilli	E	IrrE N-terminal-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M78
CMS1_k127_4153511_5	397945.Aave_4282	3.132e-10	71.0	COG4083@1|root,COG4083@2|Bacteria,1RI8D@1224|Proteobacteria,2VY0W@28216|Betaproteobacteria,4AHAS@80864|Comamonadaceae	28216|Betaproteobacteria	S	Transmembrane exosortase (Exosortase_EpsH)	-	-	-	-	-	-	-	-	-	-	-	-	Exosortase_EpsH
CMS1_k127_4159418_2	204669.Acid345_1052	2.481e-85	324.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,Trans_reg_C
CMS1_k127_4159418_5	234267.Acid_3225	5.483e-53	217.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19,TPR_8,Trans_reg_C
CMS1_k127_4159418_6	1267535.KB906767_gene4240	2.564e-51	212.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,Trans_reg_C
CMS1_k127_4159418_7	1183438.GKIL_1091	2.292e-37	166.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	-	-	2.7.1.37,2.7.11.1	ko:K00870,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Guanylate_cyc,Pkinase,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
CMS1_k127_4159418_1	204669.Acid345_1052	9.736e-111	407.0	COG0457@1|root,COG0515@1|root,COG5616@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG5616@2|Bacteria,3Y2HR@57723|Acidobacteria,2JI02@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Tetratricopeptide repeats	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,Trans_reg_C
CMS1_k127_4159418_4	1267533.KB906738_gene2351	1.666e-64	255.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,3Y7E7@57723|Acidobacteria,2JKGS@204432|Acidobacteriia	204432|Acidobacteriia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
CMS1_k127_4159418_3	234267.Acid_7393	4.3e-68	267.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y2PK@57723|Acidobacteria	57723|Acidobacteria	KLTU	WD40 domain protein beta Propeller	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase
CMS1_k127_4159418_0	234267.Acid_7572	4.16e-151	511.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
CMS1_k127_4159418_10	1265310.CCBD010000010_gene3365	7.61e-06	59.0	COG0842@1|root,COG1131@1|root,COG1716@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,COG1716@2|Bacteria,2GKEU@201174|Actinobacteria,2342I@1762|Mycobacteriaceae	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990,ko:K21397	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC_tran,FHA
CMS1_k127_4159418_11	391625.PPSIR1_23399	9.28e-05	55.0	COG4191@1|root,COG4191@2|Bacteria,1R609@1224|Proteobacteria,42MTJ@68525|delta/epsilon subdivisions,2WJYM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	COG0515 Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Pkinase
CMS1_k127_4159418_9	314287.GB2207_09596	1.139e-17	87.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,1RN41@1236|Gammaproteobacteria,1J5E0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	KT	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoB	GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042802,GO:0043254,GO:0044087,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_4159418_8	234267.Acid_4535	1.152e-20	93.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y6A7@57723|Acidobacteria	57723|Acidobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
CMS1_k127_4170697_4	1210884.HG799463_gene9717	1.861e-11	68.0	COG1262@1|root,COG1262@2|Bacteria,2IZNJ@203682|Planctomycetes	203682|Planctomycetes	CO	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
CMS1_k127_4170697_3	756272.Plabr_2156	1.505e-22	104.0	COG3399@1|root,COG3399@2|Bacteria,2IZMN@203682|Planctomycetes	203682|Planctomycetes	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4170697_2	868595.Desca_1679	1.608e-34	141.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,24IW2@186801|Clostridia,262RV@186807|Peptococcaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	algU	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_4170697_5	570268.ANBB01000016_gene3607	1.123e-06	60.0	COG3595@1|root,COG3595@2|Bacteria,2I1WD@201174|Actinobacteria,4EPZD@85012|Streptosporangiales	201174|Actinobacteria	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
CMS1_k127_4170697_0	1307759.JOMJ01000004_gene2521	2.55e-62	243.0	COG1639@1|root,COG4191@1|root,COG1639@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42Q3F@68525|delta/epsilon subdivisions,2WM2F@28221|Deltaproteobacteria,2MAB3@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	ATP-binding region ATPase domain protein, response regulator receiver, histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HDOD,HisKA,Response_reg
CMS1_k127_4170697_1	357808.RoseRS_4060	9.526e-42	177.0	COG4485@1|root,COG4485@2|Bacteria,2G75F@200795|Chloroflexi,3771H@32061|Chloroflexia	32061|Chloroflexia	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
CMS1_k127_4170697_6	1131814.JAFO01000001_gene3111	4.456e-05	48.0	COG0483@1|root,COG0483@2|Bacteria,1MV4W@1224|Proteobacteria,2TV4R@28211|Alphaproteobacteria,3EYAR@335928|Xanthobacteraceae	28211|Alphaproteobacteria	G	Inositol monophosphatase family	suhB2	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
CMS1_k127_4181107_3	525904.Tter_2452	2.262e-82	282.0	COG0395@1|root,COG0395@2|Bacteria	2|Bacteria	P	glycerophosphodiester transmembrane transport	-	-	-	ko:K02026,ko:K05815	ko02010,map02010	M00198,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.3	-	-	BPD_transp_1
CMS1_k127_4181107_2	926550.CLDAP_10190	1.434e-82	303.0	COG1175@1|root,COG1175@2|Bacteria,2G80Q@200795|Chloroflexi	200795|Chloroflexi	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_4181107_4	521045.Kole_0693	2.904e-46	191.0	COG1653@1|root,COG1653@2|Bacteria,2GCPM@200918|Thermotogae	200918|Thermotogae	G	Extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1
CMS1_k127_4181107_1	765912.Thimo_1862	2.012e-98	326.0	COG1573@1|root,COG1573@2|Bacteria,1PIX8@1224|Proteobacteria,1S0RN@1236|Gammaproteobacteria,1X0GG@135613|Chromatiales	135613|Chromatiales	L	PFAM Uracil-DNA glycosylase superfamily	-	-	-	ko:K10800	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	-
CMS1_k127_4181107_0	1267535.KB906767_gene1674	1.668e-130	451.0	COG1331@1|root,COG1331@2|Bacteria	2|Bacteria	O	Highly conserved protein containing a thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4861,Glyco_hydro_76
CMS1_k127_4190865_3	211165.AJLN01000037_gene1999	1.116e-29	119.0	COG0598@1|root,COG0598@2|Bacteria,1G1AG@1117|Cyanobacteria,1JJMP@1189|Stigonemataceae	1117|Cyanobacteria	P	CorA-like Mg2+ transporter protein	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
CMS1_k127_4190865_1	530564.Psta_2338	9.594e-115	386.0	COG3356@1|root,COG3356@2|Bacteria,2IXKA@203682|Planctomycetes	203682|Planctomycetes	S	Neutral/alkaline non-lysosomal ceramidase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
CMS1_k127_4190865_4	521045.Kole_0734	2.129e-23	113.0	COG4552@1|root,COG4552@2|Bacteria,2GE2S@200918|Thermotogae	200918|Thermotogae	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9
CMS1_k127_4190865_0	1121904.ARBP01000017_gene5093	6.208e-117	399.0	COG1409@1|root,COG1409@2|Bacteria,4NFAP@976|Bacteroidetes,47V4E@768503|Cytophagia	976|Bacteroidetes	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Fn3_assoc,Metallophos,PA14
CMS1_k127_4190865_8	929713.NIASO_01265	0.0002968	52.0	COG1525@1|root,COG1525@2|Bacteria,4NT0S@976|Bacteroidetes	976|Bacteroidetes	L	nuclease	lpxP	-	3.1.31.1	ko:K01174	-	-	-	-	ko00000,ko01000	-	-	-	SNase
CMS1_k127_4190865_2	1499967.BAYZ01000102_gene3573	5.107e-45	180.0	COG3979@1|root,COG3979@2|Bacteria	2|Bacteria	S	chitin catabolic process	chiA	GO:0003674,GO:0003824,GO:0004553,GO:0004568,GO:0005575,GO:0005623,GO:0008843,GO:0016787,GO:0016798,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	3.2.1.14,3.2.1.17	ko:K01183,ko:K03933,ko:K13381	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	AA10,CBM15,CBM73,GH18	-	CBM_5_12,DUF5011,LPMO_10,Peptidase_M60
CMS1_k127_4190865_5	1148.1001482	1.63e-21	110.0	COG2755@1|root,COG2755@2|Bacteria,1G060@1117|Cyanobacteria,1H6CY@1142|Synechocystis	1117|Cyanobacteria	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL
CMS1_k127_4190865_6	497964.CfE428DRAFT_4921	2.417e-18	99.0	COG3203@1|root,COG3203@2|Bacteria,46SY8@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Alginate export	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp
CMS1_k127_4190865_7	502025.Hoch_3311	5.402e-08	65.0	COG0793@1|root,COG0793@2|Bacteria,1QT96@1224|Proteobacteria,437TZ@68525|delta/epsilon subdivisions,2X33H@28221|Deltaproteobacteria,2YU2B@29|Myxococcales	28221|Deltaproteobacteria	MQ	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,PDZ_2
CMS1_k127_4196474_0	1047013.AQSP01000075_gene1425	1.783e-55	201.0	COG0778@1|root,COG0778@2|Bacteria,2NPKE@2323|unclassified Bacteria	2|Bacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CMS1_k127_4196474_10	1131553.JIBI01000020_gene219	3.82e-07	52.0	2DDM5@1|root,2ZII8@2|Bacteria,1P40F@1224|Proteobacteria,2W552@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4196474_2	1430440.MGMSRv2_1983	2.117e-24	109.0	2DNPH@1|root,32YF1@2|Bacteria,1NARM@1224|Proteobacteria,2UJNP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4196474_9	253839.SSNG_03734	7.071e-09	57.0	2B7FZ@1|root,320JU@2|Bacteria,2IQBZ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4196474_5	1408823.AXUS01000040_gene1668	4.634e-15	74.0	2C8B1@1|root,2ZGXF@2|Bacteria,1W39A@1239|Firmicutes,24W8J@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4196474_8	411490.ANACAC_03280	1.922e-11	65.0	2B9ZZ@1|root,323DM@2|Bacteria,1V6N4@1239|Firmicutes,24K1H@186801|Clostridia	186801|Clostridia	S	COG NOG15344 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4196474_7	363253.LI1148	4.961e-12	69.0	2B9ZZ@1|root,323DM@2|Bacteria,1MZ6J@1224|Proteobacteria,42WB2@68525|delta/epsilon subdivisions,2WWEJ@28221|Deltaproteobacteria,2MFC3@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	COG NOG15344 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4196474_3	471874.PROSTU_00109	1.867e-22	98.0	29XIP@1|root,30J9M@2|Bacteria,1QGXJ@1224|Proteobacteria,1TEDR@1236|Gammaproteobacteria,3ZADK@586|Providencia	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4196474_1	1397666.RS24_01960	1.895e-33	129.0	2AU0F@1|root,31JKB@2|Bacteria,1RGGF@1224|Proteobacteria,2U8PC@28211|Alphaproteobacteria,4BRYT@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	COG NOG14600 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4200175_1	404589.Anae109_4242	5.67e-35	141.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,43BKG@68525|delta/epsilon subdivisions,2X6YU@28221|Deltaproteobacteria,2YYW6@29|Myxococcales	28221|Deltaproteobacteria	K	ATPase associated with various cellular activities, AAA_5	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,PAS_9,Sigma54_activat
CMS1_k127_4200175_3	998674.ATTE01000001_gene1707	5.6e-14	82.0	COG1266@1|root,COG1266@2|Bacteria,1QPQ0@1224|Proteobacteria,1S8GA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
CMS1_k127_4200175_0	1123242.JH636434_gene3333	8.09e-107	357.0	COG4692@1|root,COG4692@2|Bacteria,2J06F@203682|Planctomycetes	203682|Planctomycetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
CMS1_k127_4200175_2	1210884.HG799475_gene15229	1.787e-27	117.0	COG3119@1|root,COG3119@2|Bacteria,2IYGF@203682|Planctomycetes	203682|Planctomycetes	P	Domain of unknown function (DUF4976)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CMS1_k127_420075_4	471854.Dfer_4410	3.738e-15	83.0	COG3356@1|root,COG3356@2|Bacteria,4NGDG@976|Bacteroidetes,47JVE@768503|Cytophagia	976|Bacteroidetes	S	Neutral/alkaline non-lysosomal ceramidase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
CMS1_k127_420075_0	240015.ACP_2330	2.79e-60	219.0	COG1024@1|root,COG1024@2|Bacteria,3Y47B@57723|Acidobacteria,2JIRS@204432|Acidobacteriia	204432|Acidobacteriia	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
CMS1_k127_420075_1	266117.Rxyl_0831	3.358e-23	112.0	COG1609@1|root,COG1609@2|Bacteria,2GNVD@201174|Actinobacteria,4CRZ8@84995|Rubrobacteria	84995|Rubrobacteria	K	periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
CMS1_k127_420075_3	247490.KSU1_C1333	9.104e-17	91.0	COG4968@1|root,COG4968@2|Bacteria,2J519@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CMS1_k127_420075_5	7234.FBpp0186412	1.779e-07	59.0	COG0666@1|root,KOG4177@2759|Eukaryota,38EUY@33154|Opisthokonta,3BAA9@33208|Metazoa,3CRYK@33213|Bilateria,41TKM@6656|Arthropoda,3SI1R@50557|Insecta,450P3@7147|Diptera,45QRB@7214|Drosophilidae	33208|Metazoa	M	NAD ADP-ribosyltransferase activity	TNKS2	GO:0000209,GO:0000226,GO:0000228,GO:0000242,GO:0000278,GO:0000723,GO:0000781,GO:0000784,GO:0000922,GO:0003674,GO:0003824,GO:0003950,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005643,GO:0005654,GO:0005694,GO:0005737,GO:0005794,GO:0005813,GO:0005815,GO:0005819,GO:0005829,GO:0005856,GO:0006139,GO:0006259,GO:0006355,GO:0006357,GO:0006464,GO:0006468,GO:0006471,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007010,GO:0007017,GO:0007049,GO:0007051,GO:0007052,GO:0007063,GO:0007088,GO:0007346,GO:0008104,GO:0008150,GO:0008152,GO:0008270,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009896,GO:0009966,GO:0009967,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010564,GO:0010604,GO:0010605,GO:0010628,GO:0010638,GO:0010639,GO:0010646,GO:0010647,GO:0010948,GO:0012505,GO:0015630,GO:0016020,GO:0016043,GO:0016310,GO:0016567,GO:0016604,GO:0016740,GO:0016757,GO:0016763,GO:0018105,GO:0018107,GO:0018193,GO:0018209,GO:0018210,GO:0019219,GO:0019222,GO:0019538,GO:0019899,GO:0022402,GO:0022607,GO:0023051,GO:0023056,GO:0030111,GO:0030162,GO:0030177,GO:0031090,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031331,GO:0031965,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0032200,GO:0032204,GO:0032205,GO:0032206,GO:0032210,GO:0032212,GO:0032268,GO:0032270,GO:0032446,GO:0032501,GO:0032502,GO:0032991,GO:0033036,GO:0033043,GO:0033044,GO:0033045,GO:0033046,GO:0033047,GO:0033048,GO:0033365,GO:0034091,GO:0034092,GO:0034182,GO:0034183,GO:0034502,GO:0034613,GO:0034641,GO:0035264,GO:0036211,GO:0040007,GO:0040008,GO:0040014,GO:0042176,GO:0042393,GO:0042592,GO:0043085,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043254,GO:0043392,GO:0043412,GO:0044085,GO:0044087,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044450,GO:0044451,GO:0044454,GO:0044464,GO:0045732,GO:0045786,GO:0045839,GO:0045862,GO:0045875,GO:0045893,GO:0045930,GO:0045934,GO:0045935,GO:0045944,GO:0046483,GO:0046872,GO:0046914,GO:0048471,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048589,GO:0048638,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0051052,GO:0051053,GO:0051054,GO:0051098,GO:0051100,GO:0051101,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051179,GO:0051225,GO:0051239,GO:0051246,GO:0051247,GO:0051252,GO:0051254,GO:0051276,GO:0051338,GO:0051347,GO:0051641,GO:0051726,GO:0051783,GO:0051784,GO:0051972,GO:0051973,GO:0051983,GO:0051985,GO:0060249,GO:0060255,GO:0060828,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070198,GO:0070212,GO:0070213,GO:0070647,GO:0070727,GO:0070925,GO:0071704,GO:0071840,GO:0072686,GO:0080090,GO:0090263,GO:0090304,GO:0090364,GO:0097110,GO:0097431,GO:0098687,GO:1901360,GO:1901564,GO:1902680,GO:1902850,GO:1903047,GO:1903050,GO:1903052,GO:1903362,GO:1903364,GO:1903506,GO:1903508,GO:1904353,GO:1904355,GO:1904356,GO:1904357,GO:1904358,GO:1904742,GO:1904743,GO:1904907,GO:1904908,GO:2000058,GO:2000060,GO:2000112,GO:2000278,GO:2000573,GO:2001141,GO:2001251,GO:2001252	2.4.2.30	ko:K10799	-	-	-	-	ko00000,ko01000,ko03032,ko03036	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5,PARP,SAM_2
CMS1_k127_420075_2	247490.KSU1_C1333	2.709e-19	92.0	COG4968@1|root,COG4968@2|Bacteria,2J519@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CMS1_k127_4216425_0	1499967.BAYZ01000095_gene4190	3.39e-65	232.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	CBM9_2,HATPase_c,HisKA,Response_reg
CMS1_k127_4216425_2	468059.AUHA01000002_gene1001	2.944e-11	77.0	28KZC@1|root,2ZAEP@2|Bacteria,4NITB@976|Bacteroidetes,1IVQJ@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4216425_1	1121405.dsmv_3256	5.642e-62	226.0	COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,42NF0@68525|delta/epsilon subdivisions,2WIJK@28221|Deltaproteobacteria,2MHPA@213118|Desulfobacterales	28221|Deltaproteobacteria	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
CMS1_k127_4225262_2	1500890.JQNL01000001_gene3430	2.824e-15	77.0	2AEBC@1|root,3145T@2|Bacteria,1PTKE@1224|Proteobacteria,1T6WX@1236|Gammaproteobacteria,1X8BU@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4225262_1	443598.AUFA01000009_gene5715	2.038e-32	127.0	COG1943@1|root,COG1943@2|Bacteria,1MX19@1224|Proteobacteria,2UDW5@28211|Alphaproteobacteria,3K4D3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
CMS1_k127_4225262_0	316056.RPC_4507	9.395e-34	134.0	COG1943@1|root,COG1943@2|Bacteria,1MX19@1224|Proteobacteria,2UDW5@28211|Alphaproteobacteria,3K4D3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
CMS1_k127_4225262_3	671143.DAMO_0720	4.797e-09	58.0	COG1669@1|root,COG1669@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
CMS1_k127_422958_5	1173023.KE650771_gene5224	0.0002075	48.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1JJIX@1189|Stigonemataceae	1117|Cyanobacteria	Q	Thioesterase domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_12,Methyltransf_25,PP-binding,Thioesterase
CMS1_k127_422958_0	232346.JHQL01000006_gene3004	4.543e-115	383.0	COG1819@1|root,COG1819@2|Bacteria,1MW1K@1224|Proteobacteria,1SD4P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	CG	UDP-glucoronosyl and UDP-glucosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	UDPGT
CMS1_k127_422958_2	742726.HMPREF9448_02737	6.277e-109	372.0	COG1397@1|root,COG1397@2|Bacteria,4NG36@976|Bacteroidetes,2FNB7@200643|Bacteroidia,22X71@171551|Porphyromonadaceae	976|Bacteroidetes	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
CMS1_k127_422958_4	497964.CfE428DRAFT_2751	5.131e-21	94.0	COG0551@1|root,COG0551@2|Bacteria,46V7C@74201|Verrucomicrobia	74201|Verrucomicrobia	L	DNA topoisomerase type I activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_422958_1	1283300.ATXB01000001_gene1168	3.185e-112	372.0	COG0369@1|root,COG0369@2|Bacteria,1NCKQ@1224|Proteobacteria,1RR4U@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	PFAM Oxidoreductase FAD NAD(P)-binding	-	-	1.14.13.208,1.18.1.2,1.8.1.2	ko:K00380,ko:K02641,ko:K15511	ko00195,ko00362,ko00920,ko01100,ko01120,map00195,map00362,map00920,map01100,map01120	M00176	R00858,R09555	RC00065,RC01739	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	FAD_binding_6,Fer4,NAD_binding_1
CMS1_k127_422958_3	945713.IALB_1007	1.24e-72	255.0	COG0383@1|root,COG0383@2|Bacteria	2|Bacteria	G	mannose metabolic process	mngB	GO:0003674,GO:0003824,GO:0004553,GO:0004559,GO:0005975,GO:0005996,GO:0006013,GO:0006464,GO:0006517,GO:0006807,GO:0008150,GO:0008152,GO:0009100,GO:0009987,GO:0015923,GO:0016787,GO:0016798,GO:0019318,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0071704,GO:1901135,GO:1901564	3.2.1.170,3.2.1.24	ko:K01191,ko:K15524	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	iEcolC_1368.EcolC_2924,iSF_1195.SF0565,iSFxv_1172.SFxv_0623,iS_1188.S0578	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
CMS1_k127_4231926_11	1123508.JH636444_gene5649	4.11e-13	72.0	COG1595@1|root,COG1595@2|Bacteria,2J090@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_4231926_10	1038860.AXAP01000033_gene4449	2.631e-13	74.0	COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria,2U24Y@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Integrase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve,rve_3
CMS1_k127_4231926_6	338966.Ppro_0472	6.93e-49	183.0	COG1014@1|root,COG1014@2|Bacteria,1N0EJ@1224|Proteobacteria,42UN6@68525|delta/epsilon subdivisions,2WQCE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM pyruvate ferredoxin flavodoxin oxidoreductase	-	-	1.2.7.1	ko:K00172	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
CMS1_k127_4231926_7	338966.Ppro_0471	1.031e-29	120.0	COG1144@1|root,COG1144@2|Bacteria,1NE6F@1224|Proteobacteria,42W4G@68525|delta/epsilon subdivisions,2WS1A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	oxidoreductase, delta subunit	-	-	1.2.7.1	ko:K00171	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4
CMS1_k127_4231926_1	338966.Ppro_0470	5.844e-152	495.0	COG0674@1|root,COG0674@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2WJG3@28221|Deltaproteobacteria,43TT3@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Pyruvate:ferredoxin oxidoreductase core domain II	-	-	1.2.7.1	ko:K00169	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
CMS1_k127_4231926_2	338966.Ppro_0469	2.056e-105	350.0	COG1013@1|root,COG1013@2|Bacteria,1MUY9@1224|Proteobacteria,42MQY@68525|delta/epsilon subdivisions,2WJGJ@28221|Deltaproteobacteria,43UKU@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.1	ko:K00170	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
CMS1_k127_4231926_0	661478.OP10G_0590	6.354e-281	903.0	COG3940@1|root,COG3940@2|Bacteria	2|Bacteria	G	arabinan catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106,Glyco_hydro_2_N,Glyco_hydro_43,Laminin_G_3
CMS1_k127_4231926_3	1123248.KB893381_gene955	9.653e-88	325.0	COG3408@1|root,COG3408@2|Bacteria,4P4HZ@976|Bacteroidetes	976|Bacteroidetes	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4231926_8	1267535.KB906767_gene1828	6.967e-26	109.0	COG3518@1|root,COG3518@2|Bacteria	2|Bacteria	S	anti-sigma factor antagonist activity	iraD	GO:0000988,GO:0000989,GO:0003674,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010605,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033554,GO:0042176,GO:0042177,GO:0043856,GO:0045893,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051248,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K11897,ko:K21637	-	M00334	-	-	ko00000,ko00002,ko02044	-	-	-	GPW_gp25
CMS1_k127_4231926_4	452637.Oter_3509	4.811e-81	288.0	COG0673@1|root,COG0673@2|Bacteria,46TMZ@74201|Verrucomicrobia,3K8Y2@414999|Opitutae	414999|Opitutae	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_4231926_9	1123242.JH636434_gene5340	2.226e-16	86.0	COG1413@1|root,COG1413@2|Bacteria,2IZE1@203682|Planctomycetes	203682|Planctomycetes	C	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
CMS1_k127_4231926_5	485918.Cpin_4669	2.026e-51	196.0	COG1082@1|root,COG1082@2|Bacteria,4NJJZ@976|Bacteroidetes,1IQTR@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Xylose	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS1_k127_4232653_0	525897.Dbac_2556	4.375e-44	173.0	COG1874@1|root,COG1874@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	3.2.1.23,3.2.1.4	ko:K01179,ko:K01190,ko:K12308	ko00052,ko00500,ko00511,ko00600,ko01100,map00052,map00500,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114,R06200,R11307,R11308	RC00049,RC00452	ko00000,ko00001,ko01000	-	GH5,GH9	-	Bac_rhamnosid_C,CBM_6,DUF4832,DUF4978,F5_F8_type_C,FIVAR,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_42,NPCBM,PA,TSP_3
CMS1_k127_4232653_1	1122129.AUEF01000007_gene1920	1.929e-08	56.0	COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,4HADJ@91061|Bacilli,4GXND@90964|Staphylococcaceae	91061|Bacilli	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
CMS1_k127_4232969_0	1267535.KB906767_gene4930	1.556e-126	416.0	COG2006@1|root,COG2006@2|Bacteria	2|Bacteria	U	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
CMS1_k127_4235910_8	1123366.TH3_10276	1.643e-13	72.0	COG2022@1|root,COG2104@1|root,COG2022@2|Bacteria,COG2104@2|Bacteria,1N0N5@1224|Proteobacteria,2TSXS@28211|Alphaproteobacteria,2JPMG@204441|Rhodospirillales	204441|Rhodospirillales	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG,ThiS
CMS1_k127_4235910_0	933262.AXAM01000002_gene533	3.186e-62	222.0	COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,42R5Z@68525|delta/epsilon subdivisions,2WMPN@28221|Deltaproteobacteria,2MJH1@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Thiamine monophosphate synthase	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
CMS1_k127_4235910_3	321327.CYA_1312	1.049e-41	159.0	COG1708@1|root,COG1708@2|Bacteria,1GB1D@1117|Cyanobacteria	1117|Cyanobacteria	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
CMS1_k127_4235910_7	1163617.SCD_n01378	2.07e-23	106.0	COG2250@1|root,COG2250@2|Bacteria,1NGJT@1224|Proteobacteria,2W5VI@28216|Betaproteobacteria	28216|Betaproteobacteria	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
CMS1_k127_4235910_4	485913.Krac_4464	1.071e-38	151.0	COG0735@1|root,COG0735@2|Bacteria,2G9HJ@200795|Chloroflexi	200795|Chloroflexi	P	Ferric uptake regulator family	-	-	-	ko:K22297	-	-	-	-	ko00000,ko03000	-	-	-	FUR
CMS1_k127_4235910_6	243090.RB4433	2.935e-35	140.0	COG0783@1|root,COG0783@2|Bacteria,2IZJP@203682|Planctomycetes	203682|Planctomycetes	P	Belongs to the Dps family	-	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
CMS1_k127_4235910_9	3055.EDO98576	1.367e-10	71.0	2CR7F@1|root,2S46S@2759|Eukaryota,37WJT@33090|Viridiplantae,34IB7@3041|Chlorophyta	3041|Chlorophyta	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS1_k127_4235910_2	575540.Isop_0606	5.497e-47	178.0	COG1413@1|root,COG1413@2|Bacteria,2J0ZX@203682|Planctomycetes	203682|Planctomycetes	C	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CMS1_k127_4235910_1	1123242.JH636434_gene4911	1.279e-50	196.0	COG3356@1|root,COG3356@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
CMS1_k127_4235910_5	439235.Dalk_4663	3.478e-38	150.0	COG2866@1|root,COG2866@2|Bacteria,1MZYN@1224|Proteobacteria,42PTT@68525|delta/epsilon subdivisions,2WS13@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Zn_pept	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
CMS1_k127_4242959_3	1195236.CTER_4163	4.299e-47	173.0	COG0637@1|root,COG0637@2|Bacteria,1VSTY@1239|Firmicutes,24Z1J@186801|Clostridia	186801|Clostridia	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
CMS1_k127_4242959_1	697281.Mahau_0030	1.406e-183	581.0	28MXM@1|root,2ZB4M@2|Bacteria,1V0PQ@1239|Firmicutes,24ENW@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4242959_0	243090.RB8440	1.361e-215	677.0	COG4102@1|root,COG4102@2|Bacteria,2IX70@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CMS1_k127_4242959_2	595460.RRSWK_05211	1.877e-53	191.0	COG2010@1|root,COG2010@2|Bacteria,2IX5D@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
CMS1_k127_4253786_6	118168.MC7420_6863	0.0004132	43.0	COG4576@1|root,COG4576@2|Bacteria,1G7WP@1117|Cyanobacteria,1HCHB@1150|Oscillatoriales	1117|Cyanobacteria	CQ	Carbon dioxide concentrating mechanism carboxysome shell protein	ccmL	-	-	ko:K08697	-	-	-	-	ko00000	-	-	-	EutN_CcmL
CMS1_k127_4253786_4	215803.DB30_1141	2.431e-39	148.0	COG4577@1|root,COG4577@2|Bacteria,1RH1U@1224|Proteobacteria,42UCN@68525|delta/epsilon subdivisions,2WQ3V@28221|Deltaproteobacteria,2Z195@29|Myxococcales	28221|Deltaproteobacteria	CQ	BMC	-	-	-	ko:K04027	-	-	-	-	ko00000	-	-	-	BMC
CMS1_k127_4253786_2	56110.Oscil6304_5272	1.63e-68	238.0	COG4577@1|root,COG4577@2|Bacteria,1G0GA@1117|Cyanobacteria,1H73J@1150|Oscillatoriales	1117|Cyanobacteria	CQ	PFAM BMC domain	-	-	-	-	-	-	-	-	-	-	-	-	BMC
CMS1_k127_4253786_3	493475.GARC_1198	3.084e-41	156.0	COG3428@1|root,COG3428@2|Bacteria,1NHMM@1224|Proteobacteria	1224|Proteobacteria	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
CMS1_k127_4253786_1	765420.OSCT_2959	1.834e-99	334.0	COG0115@1|root,COG0115@2|Bacteria,2G6AX@200795|Chloroflexi,37550@32061|Chloroflexia	32061|Chloroflexia	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
CMS1_k127_4253786_0	1303518.CCALI_00632	4.309e-107	361.0	COG0399@1|root,COG0399@2|Bacteria	2|Bacteria	E	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
CMS1_k127_4253786_5	1122917.KB899661_gene1195	1.359e-16	84.0	COG1262@1|root,COG4409@1|root,COG1262@2|Bacteria,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2,FGE-sulfatase
CMS1_k127_4257524_17	97139.C824_01928	1.145e-06	51.0	COG0673@1|root,COG0673@2|Bacteria,1TP83@1239|Firmicutes,248XQ@186801|Clostridia,36F4R@31979|Clostridiaceae	186801|Clostridia	S	Oxidoreductase family, C-terminal alpha beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_4257524_14	643648.Slip_0318	3.895e-22	109.0	COG0407@1|root,COG0407@2|Bacteria,1USM0@1239|Firmicutes,248G3@186801|Clostridia,42K8G@68298|Syntrophomonadaceae	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
CMS1_k127_4257524_7	1123508.JH636444_gene5664	8.725e-53	194.0	COG0500@1|root,COG2226@2|Bacteria,2IZR2@203682|Planctomycetes	203682|Planctomycetes	Q	COG2226 Methylase involved in ubiquinone menaquinone biosynthesis	-	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_25
CMS1_k127_4257524_1	1168034.FH5T_01575	6.131e-148	485.0	COG1520@1|root,COG1520@2|Bacteria,4P15Y@976|Bacteroidetes,2FWBU@200643|Bacteroidia	976|Bacteroidetes	S	PQQ-like domain	-	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2
CMS1_k127_4257524_9	595460.RRSWK_06184	1.681e-44	174.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	NHL
CMS1_k127_4257524_6	1168034.FH5T_01560	1.009e-66	231.0	2DVMZ@1|root,33WFQ@2|Bacteria,4P3VR@976|Bacteroidetes,2FXVM@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	-
CMS1_k127_4257524_2	1168034.FH5T_01555	1.76e-110	372.0	COG0348@1|root,COG0348@2|Bacteria,4NPVD@976|Bacteroidetes,2FTEY@200643|Bacteroidia	976|Bacteroidetes	C	FMN-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_5
CMS1_k127_4257524_3	1168034.FH5T_01550	3.931e-108	372.0	COG1520@1|root,COG1520@2|Bacteria,4P1VG@976|Bacteroidetes,2FW8D@200643|Bacteroidia	976|Bacteroidetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CMS1_k127_4257524_0	555079.Toce_0242	4.612e-191	625.0	COG1894@1|root,COG1894@2|Bacteria,1TQB0@1239|Firmicutes,2483E@186801|Clostridia,42I0X@68295|Thermoanaerobacterales	186801|Clostridia	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	nuoF2	-	1.12.1.3,1.6.5.3	ko:K00335,ko:K18331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,Fer4_20,NADH_4Fe-4S,Pyr_redox_2,SLBB
CMS1_k127_4257524_4	595460.RRSWK_05849	2.072e-103	354.0	COG0493@1|root,COG3383@1|root,COG0493@2|Bacteria,COG3383@2|Bacteria,2J2W6@203682|Planctomycetes	203682|Planctomycetes	E	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_4,Fer4_20,Pyr_redox_2
CMS1_k127_4257524_16	247490.KSU1_C1333	3.959e-15	87.0	COG4968@1|root,COG4968@2|Bacteria,2J519@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CMS1_k127_4257524_5	1168034.FH5T_01595	1.549e-96	331.0	COG1520@1|root,COG1520@2|Bacteria,4P28I@976|Bacteroidetes,2FX0J@200643|Bacteroidia	976|Bacteroidetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CMS1_k127_4257524_8	319224.Sputcn32_3833	6.093e-50	186.0	COG4232@1|root,COG4232@2|Bacteria,1QJ3E@1224|Proteobacteria,1TH0Z@1236|Gammaproteobacteria,2QDT4@267890|Shewanellaceae	1236|Gammaproteobacteria	CO	PFAM cytochrome c biogenesis protein, transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	DsbD_2
CMS1_k127_4257524_13	1499967.BAYZ01000050_gene2875	5.491e-23	105.0	2DPAK@1|root,33193@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4257524_11	641491.DND132_2314	1.536e-24	109.0	COG4273@1|root,COG4273@2|Bacteria,1MZED@1224|Proteobacteria,42UH2@68525|delta/epsilon subdivisions,2WQNQ@28221|Deltaproteobacteria,2MBB6@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	DGC domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DGC
CMS1_k127_4257524_12	1499967.BAYZ01000050_gene2842	4.708e-24	104.0	COG0526@1|root,COG0526@2|Bacteria,2NQ71@2323|unclassified Bacteria	2|Bacteria	CO	Thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4369,Thioredoxin_3
CMS1_k127_4257524_18	1196322.A370_03179	5.876e-05	49.0	2EDZU@1|root,337UN@2|Bacteria,1VJC0@1239|Firmicutes,24TRR@186801|Clostridia,36MDR@31979|Clostridiaceae	186801|Clostridia	L	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
CMS1_k127_4257524_10	1168034.FH5T_18125	5.559e-40	152.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CMS1_k127_4268025_1	1382306.JNIM01000001_gene897	3.338e-54	199.0	COG0631@1|root,COG0631@2|Bacteria,2G6R4@200795|Chloroflexi	200795|Chloroflexi	T	SMART protein phosphatase 2C domain protein	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
CMS1_k127_4268025_2	1042156.CXIVA_21600	1.525e-26	123.0	COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,24ASN@186801|Clostridia,36FMH@31979|Clostridiaceae	186801|Clostridia	L	DNA polymerase III delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
CMS1_k127_4268025_5	1131269.AQVV01000012_gene2603	3.365e-09	65.0	COG2980@1|root,COG2980@2|Bacteria	2|Bacteria	M	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane	lptE	GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264	-	ko:K03643	-	-	-	-	ko00000,ko02000	1.B.42.1	-	iECH74115_1262.ECH74115_0730,iECSP_1301.ECSP_0694,iECs_1301.ECs0679,iG2583_1286.G2583_0804,iZ_1308.Z0788	LptE
CMS1_k127_4268025_4	497964.CfE428DRAFT_3832	3.16e-17	93.0	COG1729@1|root,COG4105@1|root,COG1729@2|Bacteria,COG4105@2|Bacteria,46SYU@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Tetratricopeptide TPR_2 repeat protein	-	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	TPR_16,TPR_6,YfiO
CMS1_k127_4268025_0	153721.MYP_1903	6.29e-83	292.0	COG0738@1|root,COG0738@2|Bacteria,4NFTC@976|Bacteroidetes,47K9V@768503|Cytophagia	976|Bacteroidetes	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_4268025_3	580332.Slit_0824	5.235e-18	84.0	COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,2VNWB@28216|Betaproteobacteria	28216|Betaproteobacteria	E	PFAM aminotransferase class V	-	-	2.6.1.44,2.6.1.45,2.6.1.51	ko:K00830	ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	M00346,M00532	R00369,R00372,R00585,R00588	RC00006,RC00008,RC00018	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
CMS1_k127_4270666_0	1168034.FH5T_08475	3.654e-40	171.0	COG2133@1|root,COG2911@1|root,COG3227@1|root,COG2133@2|Bacteria,COG2911@2|Bacteria,COG3227@2|Bacteria	2|Bacteria	E	Zinc metalloprotease (Elastase)	-	-	-	-	-	-	-	-	-	-	-	-	MAM,PATR,Peptidase_M43,fn3
CMS1_k127_4270666_1	110663.KI911558_gene1854	5.21e-09	70.0	COG0265@1|root,COG3420@1|root,COG5276@1|root,COG0265@2|Bacteria,COG3420@2|Bacteria,COG5276@2|Bacteria,1GQQP@1117|Cyanobacteria,1H4EF@1129|Synechococcus	1117|Cyanobacteria	O	alginic acid biosynthetic process	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	-
CMS1_k127_4271040_2	1183438.GKIL_3078	1.105e-30	136.0	COG1807@1|root,COG1807@2|Bacteria,1GCPV@1117|Cyanobacteria	1117|Cyanobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS1_k127_4271040_0	1173021.ALWA01000017_gene2186	2.292e-254	799.0	COG0021@1|root,COG0021@2|Bacteria,1G0B5@1117|Cyanobacteria	1117|Cyanobacteria	G	Belongs to the transketolase family	-	-	-	-	-	-	-	-	-	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
CMS1_k127_4271040_6	575540.Isop_1073	4.767e-14	79.0	COG1404@1|root,COG4935@1|root,COG1404@2|Bacteria,COG4935@2|Bacteria,2J3AX@203682|Planctomycetes	2|Bacteria	O	COGs COG4935 Regulatory P domain of the subtilisin-like proprotein convertase and other protease	prcA	-	3.4.21.121	ko:K13735,ko:K20276,ko:K20755,ko:K21449	ko02024,ko05100,map02024,map05100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko02000	1.B.40.2	-	-	B_lectin,Calx-beta,P_proprotein,Peptidase_S8
CMS1_k127_4271040_1	1396418.BATQ01000186_gene2161	1.807e-165	545.0	COG3401@1|root,COG3401@2|Bacteria	2|Bacteria	Q	FG-GAP repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
CMS1_k127_4271040_5	992406.RIA_0409	1.265e-16	91.0	28MB1@1|root,2ZAPK@2|Bacteria,4NHMB@976|Bacteroidetes,1I0EB@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4271040_4	1968.JOEV01000028_gene4827	1.35e-17	98.0	COG3250@1|root,COG3250@2|Bacteria,2GMAT@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.2.1.31	ko:K01195	ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142	M00014,M00076,M00077,M00078,M00129	R01478,R04979,R07818,R08127,R08260,R10830	RC00055,RC00171,RC00529,RC00530,RC00714,RC01251	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
CMS1_k127_4271040_3	1121920.AUAU01000001_gene2240	1.201e-30	124.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,Thioredoxin,Thioredoxin_9
CMS1_k127_4280925_0	886293.Sinac_5779	7.156e-102	344.0	COG0673@1|root,COG0673@2|Bacteria,2IYB5@203682|Planctomycetes	203682|Planctomycetes	S	PFAM oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_4280925_1	470.IX87_02390	3.08e-14	85.0	COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,1RMWU@1236|Gammaproteobacteria,3NIEI@468|Moraxellaceae	1236|Gammaproteobacteria	M	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	surA	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006457,GO:0006458,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0022607,GO:0030288,GO:0030313,GO:0031647,GO:0031975,GO:0033218,GO:0036211,GO:0042277,GO:0042597,GO:0043163,GO:0043165,GO:0043170,GO:0043412,GO:0044085,GO:0044091,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0044764,GO:0045229,GO:0050821,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0060274,GO:0061024,GO:0061077,GO:0065007,GO:0065008,GO:0071704,GO:0071709,GO:0071840,GO:0140096,GO:1901564	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3,SurA_N
CMS1_k127_4285880_1	1283300.ATXB01000002_gene3078	1.069e-69	251.0	COG2202@1|root,COG2208@1|root,COG3290@1|root,COG3829@1|root,COG2202@2|Bacteria,COG2208@2|Bacteria,COG3290@2|Bacteria,COG3829@2|Bacteria,1RGZF@1224|Proteobacteria,1S6GG@1236|Gammaproteobacteria,1XDM4@135618|Methylococcales	135618|Methylococcales	KT	PFAM Stage II sporulation protein E (SpoIIE)	-	-	-	-	-	-	-	-	-	-	-	-	PAS_9,SpoIIE
CMS1_k127_4285880_0	1123248.KB893348_gene329	8.824e-83	282.0	COG3394@1|root,COG3394@2|Bacteria,4NFY5@976|Bacteroidetes,1IVCK@117747|Sphingobacteriia	976|Bacteroidetes	G	YdjC-like protein	-	-	3.5.1.105	ko:K03478	-	-	-	-	ko00000,ko01000	-	-	-	YdjC
CMS1_k127_4289400_5	377629.TERTU_2532	9.528e-06	58.0	2C6D0@1|root,31F07@2|Bacteria,1RHBN@1224|Proteobacteria,1S7HH@1236|Gammaproteobacteria,2PQB7@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
CMS1_k127_4289400_0	1123371.ATXH01000011_gene109	9.828e-128	439.0	COG1277@1|root,COG3225@1|root,COG1277@2|Bacteria,COG3225@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
CMS1_k127_4289400_1	1125863.JAFN01000001_gene2142	6.205e-84	288.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42NF6@68525|delta/epsilon subdivisions,2WKVH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_4289400_2	138119.DSY3501	2.371e-83	291.0	COG0523@1|root,COG0523@2|Bacteria,1UKHE@1239|Firmicutes,24DT4@186801|Clostridia	186801|Clostridia	S	CobW/HypB/UreG, nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cobW
CMS1_k127_4289400_3	195253.Syn6312_1329	9.95e-83	282.0	COG0500@1|root,COG2226@2|Bacteria,1G24H@1117|Cyanobacteria,1H0C4@1129|Synechococcus	1117|Cyanobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS1_k127_4289400_4	46234.ANA_C20394	2.073e-20	102.0	COG0515@1|root,COG5263@1|root,COG0515@2|Bacteria,COG5263@2|Bacteria,1G1AI@1117|Cyanobacteria,1HKZW@1161|Nostocales	1117|Cyanobacteria	KLT	PFAM KWG Leptospira	-	-	-	-	-	-	-	-	-	-	-	-	WG_beta_rep
CMS1_k127_4305_3	56780.SYN_02192	1.523e-51	190.0	COG3481@1|root,COG3481@2|Bacteria,1NH0C@1224|Proteobacteria,42Q7X@68525|delta/epsilon subdivisions,2WJW2@28221|Deltaproteobacteria,2MQGJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	nucleic acid binding	yhaM	-	-	ko:K03698	-	-	-	-	ko00000,ko01000,ko03019	-	-	-	HD,tRNA_anti-codon
CMS1_k127_4305_1	530564.Psta_3779	9.03e-113	378.0	COG1914@1|root,COG1914@2|Bacteria,2IWTS@203682|Planctomycetes	203682|Planctomycetes	P	COG1914 Mn2 and Fe2 transporters of the NRAMP family	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
CMS1_k127_4305_0	1265756.AWZW01000008_gene1121	3.862e-146	479.0	COG1232@1|root,COG1232@2|Bacteria,1MX35@1224|Proteobacteria,2TU7I@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	amine oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
CMS1_k127_4305_5	1128421.JAGA01000002_gene749	7.595e-27	126.0	COG1287@1|root,COG1287@2|Bacteria	2|Bacteria	S	oligosaccharyl transferase activity	-	-	2.4.99.18	ko:K07151	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00072	R04216,R05976	RC00005,RC00482	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT66	-	PMT_2
CMS1_k127_4305_2	1267535.KB906767_gene5001	1.433e-52	212.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,Sulfatase
CMS1_k127_4305_4	1499967.BAYZ01000125_gene2598	2.385e-46	186.0	COG3119@1|root,COG3119@2|Bacteria,2NR0Q@2323|unclassified Bacteria	2|Bacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	CBM60,Sulfatase
CMS1_k127_4306338_2	485917.Phep_4108	7.075e-40	156.0	COG3420@1|root,COG3420@2|Bacteria,4PMG9@976|Bacteroidetes,1IW7F@117747|Sphingobacteriia	976|Bacteroidetes	P	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
CMS1_k127_4306338_0	1499967.BAYZ01000103_gene3772	4.556e-193	609.0	COG5441@1|root,COG5441@2|Bacteria	2|Bacteria	S	Uncharacterised protein family (UPF0261)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0261
CMS1_k127_4306338_1	1499967.BAYZ01000103_gene3771	1.347e-92	308.0	COG5564@1|root,COG5564@2|Bacteria	2|Bacteria	S	Phosphoenolpyruvate hydrolase-like	MA20_13935	-	-	-	-	-	-	-	-	-	-	-	PEP_hydrolase
CMS1_k127_4315687_4	1510531.JQJJ01000010_gene2355	0.000134	44.0	COG1262@1|root,COG4249@1|root,COG1262@2|Bacteria,COG4249@2|Bacteria,1NQ5K@1224|Proteobacteria,2U2VJ@28211|Alphaproteobacteria,3JTPW@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Peptidase_C14
CMS1_k127_4315687_2	5147.XP_003343202.1	7.375e-10	65.0	COG0740@1|root,KOG0840@2759|Eukaryota,38PE0@33154|Opisthokonta,3P040@4751|Fungi	4751|Fungi	O	Atp-dependent clp protease proteolytic subunit	-	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
CMS1_k127_4315687_3	319225.Plut_0367	2.114e-05	56.0	COG1572@1|root,COG2304@1|root,COG2911@1|root,COG2931@1|root,COG2982@1|root,COG3210@1|root,COG3391@1|root,COG3898@1|root,COG4932@1|root,COG5276@1|root,COG1572@2|Bacteria,COG2304@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG2982@2|Bacteria,COG3210@2|Bacteria,COG3391@2|Bacteria,COG3898@2|Bacteria,COG4932@2|Bacteria,COG5276@2|Bacteria	2|Bacteria	M	domain protein	-	-	3.2.1.65,3.4.21.10	ko:K01212,ko:K01317,ko:K12287,ko:K20276	ko00500,ko02024,map00500,map02024	-	R05624,R11311	RC03278	ko00000,ko00001,ko01000,ko01002,ko02044,ko04131	-	GH32	-	DUF4347,VCBS,VWA_2
CMS1_k127_4315687_1	935948.KE386495_gene1239	1.897e-79	280.0	COG0407@1|root,COG0407@2|Bacteria,1UY51@1239|Firmicutes,24DZF@186801|Clostridia,42FW9@68295|Thermoanaerobacterales	186801|Clostridia	H	PFAM Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
CMS1_k127_4315687_0	204669.Acid345_0497	3.742e-142	469.0	COG0617@1|root,COG0617@2|Bacteria,3Y3B8@57723|Acidobacteria,2JIIS@204432|Acidobacteriia	204432|Acidobacteriia	J	Probable RNA and SrmB- binding site of polymerase A	-	-	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
CMS1_k127_4325353_0	595460.RRSWK_06361	7.048e-78	270.0	COG2335@1|root,COG2335@2|Bacteria,2IZDI@203682|Planctomycetes	203682|Planctomycetes	M	COG2335 Secreted and surface protein containing fasciclin-like repeats	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
CMS1_k127_4325353_1	502025.Hoch_2213	2.812e-50	191.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,1R2NF@1224|Proteobacteria,43AJU@68525|delta/epsilon subdivisions,2X600@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	helix_turn_helix, mercury resistance	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,MerR_1
CMS1_k127_4325353_2	765913.ThidrDRAFT_2591	2.025e-44	170.0	COG3449@1|root,COG3449@2|Bacteria,1RF2U@1224|Proteobacteria,1S2JU@1236|Gammaproteobacteria,1WY8T@135613|Chromatiales	135613|Chromatiales	L	PFAM SOUL heme-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SOUL
CMS1_k127_4325353_3	2423.NA23_0209490	2.339e-27	120.0	arCOG03622@1|root,33HZF@2|Bacteria,2GE37@200918|Thermotogae	200918|Thermotogae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4340085_3	1449050.JNLE01000003_gene3778	5.988e-05	53.0	COG5662@1|root,COG5662@2|Bacteria,1UHWV@1239|Firmicutes,24JF8@186801|Clostridia,36INK@31979|Clostridiaceae	186801|Clostridia	K	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349,zf-HC2
CMS1_k127_4340085_0	1121439.dsat_1460	1.107e-134	445.0	COG2204@1|root,COG4191@1|root,COG2204@2|Bacteria,COG4191@2|Bacteria,1QZPK@1224|Proteobacteria,42NQE@68525|delta/epsilon subdivisions,2WJPH@28221|Deltaproteobacteria,2M8MZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_4,PAS_9,Response_reg
CMS1_k127_4340085_1	706587.Desti_0283	1.815e-26	117.0	COG0745@1|root,COG0745@2|Bacteria,1NBQZ@1224|Proteobacteria,42V8P@68525|delta/epsilon subdivisions,2WS87@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS1_k127_4340085_2	1121468.AUBR01000050_gene2005	1.664e-16	87.0	COG0247@1|root,COG0247@2|Bacteria,1UZQ0@1239|Firmicutes,24E5H@186801|Clostridia,42F8Q@68295|Thermoanaerobacterales	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_17
CMS1_k127_434833_0	290397.Adeh_2253	2.978e-218	693.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,43BKG@68525|delta/epsilon subdivisions,2X6YU@28221|Deltaproteobacteria,2YYW6@29|Myxococcales	28221|Deltaproteobacteria	K	ATPase associated with various cellular activities, AAA_5	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,PAS_9,Sigma54_activat
CMS1_k127_4348588_0	756272.Plabr_1020	3.825e-232	732.0	COG1966@1|root,COG1966@2|Bacteria,2IWZE@203682|Planctomycetes	203682|Planctomycetes	T	Carbon starvation protein	cstA	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
CMS1_k127_4348588_3	794903.OPIT5_23780	1.637e-42	160.0	2ETC2@1|root,33KVZ@2|Bacteria,46VQR@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4348588_2	1396418.BATQ01000012_gene4401	2.132e-71	245.0	2E9QR@1|root,333X2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4348588_1	886882.PPSC2_c3904	3.824e-118	402.0	COG3291@1|root,COG3420@1|root,COG3291@2|Bacteria,COG3420@2|Bacteria,1UY76@1239|Firmicutes,4ISNW@91061|Bacilli,2775C@186822|Paenibacillaceae	91061|Bacilli	P	Right handed beta helix region	galA	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
CMS1_k127_4387171_1	1121875.KB907548_gene1638	1.469e-75	264.0	COG0644@1|root,COG0644@2|Bacteria,4P040@976|Bacteroidetes	976|Bacteroidetes	C	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4387171_0	1125863.JAFN01000001_gene2788	9.059e-136	440.0	COG0348@1|root,COG3350@1|root,COG0348@2|Bacteria,COG3350@2|Bacteria,1R9MN@1224|Proteobacteria,42QKX@68525|delta/epsilon subdivisions,2WMMH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	CT	Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_5,Sigma54_activat,cNMP_binding
CMS1_k127_4393172_1	234267.Acid_5708	9.694e-202	635.0	COG4102@1|root,COG4102@2|Bacteria,3Y793@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CMS1_k127_4393172_0	886293.Sinac_1516	5.183e-254	807.0	COG5492@1|root,COG5492@2|Bacteria,2IXIZ@203682|Planctomycetes	203682|Planctomycetes	N	Bacterial Ig-like domain (group 2)	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,PSCyt2,PSD1
CMS1_k127_440099_2	485913.Krac_1156	1.105e-07	59.0	COG0582@1|root,COG0582@2|Bacteria,2G7XX@200795|Chloroflexi	200795|Chloroflexi	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
CMS1_k127_440099_3	269800.Tfu_3066	5.996e-06	56.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4EFPA@85012|Streptosporangiales	201174|Actinobacteria	KLT	PASTA	pknB	GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
CMS1_k127_440099_0	1128421.JAGA01000002_gene1312	2.345e-83	294.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4,Peptidase_S9
CMS1_k127_4404083_7	1460635.JCM19038_139	1.227e-17	93.0	COG1381@1|root,COG1381@2|Bacteria,1UZ19@1239|Firmicutes,4HAHI@91061|Bacilli	91061|Bacilli	L	Involved in DNA repair and RecF pathway recombination	recO	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
CMS1_k127_4404083_0	246194.CHY_0410	1.361e-251	790.0	COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,247V8@186801|Clostridia,42F8U@68295|Thermoanaerobacterales	186801|Clostridia	J	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
CMS1_k127_4404083_5	76114.ebA5536	9.971e-35	150.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,2VJ9D@28216|Betaproteobacteria,2KUHJ@206389|Rhodocyclales	206389|Rhodocyclales	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
CMS1_k127_4404083_6	694431.DESACE_00745	1.129e-29	132.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,42NJE@68525|delta/epsilon subdivisions,2WKMA@28221|Deltaproteobacteria,2M69Y@213113|Desulfurellales	28221|Deltaproteobacteria	U	Signal peptidase, peptidase S26	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
CMS1_k127_4404083_3	344747.PM8797T_21438	9.705e-65	237.0	COG0635@1|root,COG0635@2|Bacteria,2IWR5@203682|Planctomycetes	203682|Planctomycetes	H	Involved in the biosynthesis of porphyrin-containing compound	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
CMS1_k127_4404083_4	518766.Rmar_1468	2.552e-52	189.0	COG2050@1|root,COG2050@2|Bacteria,4NX1Y@976|Bacteroidetes,1FJMP@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	Q	Thioesterase superfamily	-	-	3.1.2.28	ko:K19222	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07262	RC00004,RC00174	ko00000,ko00001,ko00002,ko01000	-	-	-	4HBT
CMS1_k127_4404083_1	1232410.KI421413_gene654	3.207e-107	378.0	COG3267@1|root,COG3409@1|root,COG3267@2|Bacteria,COG3409@2|Bacteria,1MU3G@1224|Proteobacteria,42N7S@68525|delta/epsilon subdivisions,2WMBC@28221|Deltaproteobacteria,43SAE@69541|Desulfuromonadales	28221|Deltaproteobacteria	MU	SMART AAA ATPase	exeA	-	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22,PG_binding_1
CMS1_k127_4404083_2	368408.Tpen_1559	2.904e-83	282.0	COG2407@1|root,arCOG01772@2157|Archaea	2157|Archaea	G	L-fucose isomerase and related	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4407974_1	867845.KI911784_gene899	4.225e-110	373.0	COG1233@1|root,COG1233@2|Bacteria,2G68M@200795|Chloroflexi,376AV@32061|Chloroflexia	32061|Chloroflexia	Q	PFAM amine oxidase	-	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
CMS1_k127_4407974_4	194439.CT1987	2.618e-56	211.0	COG1215@1|root,COG1215@2|Bacteria,1FDR6@1090|Chlorobi	1090|Chlorobi	M	PFAM glycosyl transferase family 2	-	-	-	ko:K14597	ko00906,map00906	-	R07544,R07546	RC00262	ko00000,ko00001	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
CMS1_k127_4407974_6	246197.MXAN_3529	3.33e-12	76.0	COG0596@1|root,COG0596@2|Bacteria,1R3WK@1224|Proteobacteria,42UP3@68525|delta/epsilon subdivisions,2WQ5A@28221|Deltaproteobacteria,2YVG5@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)	menH	-	4.2.99.20	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08166	RC02148,RC02475	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_6
CMS1_k127_4407974_2	1242864.D187_009307	5.629e-110	374.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,43BX1@68525|delta/epsilon subdivisions,2X77U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Phytoene dehydrogenase	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
CMS1_k127_4407974_5	1122611.KB903985_gene3763	5.174e-35	149.0	COG1562@1|root,COG1562@2|Bacteria,2GJN2@201174|Actinobacteria,4EGJY@85012|Streptosporangiales	201174|Actinobacteria	I	Squalene/phytoene synthase	crtB	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
CMS1_k127_4407974_3	1403819.BATR01000159_gene5252	9.706e-67	241.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,46V45@74201|Verrucomicrobia,2IVR0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2,MerR_1
CMS1_k127_4407974_0	756272.Plabr_3518	1.12e-178	582.0	COG0265@1|root,COG0823@1|root,COG2234@1|root,COG0265@2|Bacteria,COG0823@2|Bacteria,COG2234@2|Bacteria,2IX8E@203682|Planctomycetes	203682|Planctomycetes	O	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,PD40,PDZ_2,Peptidase_M28
CMS1_k127_4424453_11	930169.B5T_01123	2.729e-68	238.0	COG0591@1|root,COG0591@2|Bacteria,1QUXM@1224|Proteobacteria,1T251@1236|Gammaproteobacteria,1XJTT@135619|Oceanospirillales	135619|Oceanospirillales	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
CMS1_k127_4424453_21	247490.KSU1_C1333	1.174e-17	95.0	COG4968@1|root,COG4968@2|Bacteria,2J519@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CMS1_k127_4424453_5	1235279.C772_02675	3.426e-108	370.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HA2G@91061|Bacilli,26DFP@186818|Planococcaceae	91061|Bacilli	IQ	AMP-binding enzyme C-terminal domain	lcfB_2	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
CMS1_k127_4424453_15	378806.STAUR_3193	6.838e-50	194.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42MH9@68525|delta/epsilon subdivisions,2WJE0@28221|Deltaproteobacteria,2YTZT@29|Myxococcales	28221|Deltaproteobacteria	U	General secretion pathway protein F	gspF	-	-	ko:K02455,ko:K02653	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
CMS1_k127_4424453_23	443144.GM21_0601	1.067e-09	70.0	COG3156@1|root,COG3156@2|Bacteria,1N9I4@1224|Proteobacteria,42V0N@68525|delta/epsilon subdivisions,2WRR8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	PFAM General secretion pathway protein K	gspK	-	-	ko:K02460	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSK
CMS1_k127_4424453_27	1279015.KB908467_gene484	0.0009356	49.0	COG4967@1|root,COG4967@2|Bacteria,1N992@1224|Proteobacteria,1T2RT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02458	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
CMS1_k127_4424453_0	756272.Plabr_3458	2.952e-207	667.0	COG0370@1|root,COG0370@2|Bacteria,2IYCI@203682|Planctomycetes	203682|Planctomycetes	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
CMS1_k127_4424453_20	1158601.I585_03623	6.558e-19	88.0	COG1918@1|root,COG1918@2|Bacteria,1VEHC@1239|Firmicutes,4HPFS@91061|Bacilli,4B083@81852|Enterococcaceae	91061|Bacilli	P	FeoA	feoA	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
CMS1_k127_4424453_26	633149.Bresu_1488	3.488e-05	50.0	COG1918@1|root,COG1918@2|Bacteria	2|Bacteria	P	iron ion homeostasis	feoA	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
CMS1_k127_4424453_19	880073.Calab_1710	5.226e-27	117.0	COG1321@1|root,COG1321@2|Bacteria,2NRWG@2323|unclassified Bacteria	2|Bacteria	K	Helix-turn-helix diphteria tox regulatory element	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
CMS1_k127_4424453_22	234267.Acid_6615	8.44e-17	91.0	28KX8@1|root,2ZAD8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4424453_10	420324.KI912007_gene8802	3.982e-73	256.0	COG2230@1|root,COG2230@2|Bacteria,1QUR4@1224|Proteobacteria,2TW4A@28211|Alphaproteobacteria,1JZCY@119045|Methylobacteriaceae	28211|Alphaproteobacteria	M	Mycolic acid cyclopropane synthetase	-	-	2.1.1.95	ko:K05928	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00112	R07236,R07504,R10491,R10492	RC00003,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	CMAS
CMS1_k127_4424453_24	247490.KSU1_B0661	1.182e-07	58.0	2EQMR@1|root,33I7Q@2|Bacteria,2J1A3@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4424453_9	926569.ANT_30710	1.64e-75	265.0	COG1957@1|root,COG1957@2|Bacteria,2G7IF@200795|Chloroflexi	200795|Chloroflexi	F	PFAM Inosine uridine-preferring nucleoside hydrolase	-	-	3.2.2.1	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
CMS1_k127_4424453_2	1267535.KB906767_gene4252	1.747e-201	640.0	COG3119@1|root,COG3119@2|Bacteria,3Y7FV@57723|Acidobacteria	57723|Acidobacteria	P	Protein of unknown function (DUF229)	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS1_k127_4424453_7	373903.Hore_09540	6.598e-91	310.0	COG1879@1|root,COG1879@2|Bacteria,1TQ1B@1239|Firmicutes,247K8@186801|Clostridia,3WB4J@53433|Halanaerobiales	186801|Clostridia	G	Periplasmic binding protein LacI transcriptional regulator	alsB	-	-	ko:K10439,ko:K10549	ko02010,ko02030,map02010,map02030	M00212,M00217	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.6	-	-	Peripla_BP_4
CMS1_k127_4424453_12	935948.KE386495_gene1853	6.402e-65	233.0	COG1172@1|root,COG1172@2|Bacteria,1TP72@1239|Firmicutes,249FA@186801|Clostridia,42G0Z@68295|Thermoanaerobacterales	186801|Clostridia	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
CMS1_k127_4424453_6	97139.C824_01928	1.124e-95	323.0	COG0673@1|root,COG0673@2|Bacteria,1TP83@1239|Firmicutes,248XQ@186801|Clostridia,36F4R@31979|Clostridiaceae	186801|Clostridia	S	Oxidoreductase family, C-terminal alpha beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_4424453_1	1267535.KB906767_gene2163	5.942e-202	640.0	COG2407@1|root,COG2407@2|Bacteria,3Y2FH@57723|Acidobacteria,2JI15@204432|Acidobacteriia	204432|Acidobacteriia	G	L-fucose isomerase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Fucose_iso_C
CMS1_k127_4424453_8	706587.Desti_3021	2.61e-86	314.0	COG2202@1|root,COG2204@1|root,COG3850@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2204@2|Bacteria,COG3850@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIU5@28221|Deltaproteobacteria,2MQZQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
CMS1_k127_4424453_4	479432.Sros_2360	6.349e-112	371.0	COG0451@1|root,COG0451@2|Bacteria,2GJBB@201174|Actinobacteria	201174|Actinobacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
CMS1_k127_4424453_3	886293.Sinac_0671	8.582e-143	462.0	COG0329@1|root,COG0329@2|Bacteria,2IXEF@203682|Planctomycetes	203682|Planctomycetes	EM	Belongs to the DapA family	-	-	-	-	-	-	-	-	-	-	-	-	DHDPS
CMS1_k127_4424453_18	759362.KVU_1356	1.864e-29	127.0	COG1082@1|root,COG1082@2|Bacteria,1Q7T1@1224|Proteobacteria,2UMAR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS1_k127_4424453_17	1121324.CLIT_23c03160	2.811e-37	149.0	COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,24JHR@186801|Clostridia,25RB7@186804|Peptostreptococcaceae	186801|Clostridia	L	RNA methyltransferase, RsmD family	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
CMS1_k127_4424453_13	1009370.ALO_14407	3.117e-56	199.0	COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,4H4DR@909932|Negativicutes	909932|Negativicutes	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
CMS1_k127_4424453_16	1123248.KB893385_gene4825	5.348e-48	186.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GSDH,Phage-tail_3,TIG
CMS1_k127_4424453_14	63737.Npun_DR029	7.518e-52	197.0	COG4257@1|root,COG4257@2|Bacteria	2|Bacteria	V	antibiotic catabolic process	-	-	-	ko:K13277	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	DUF5011,FG-GAP_2,NHL
CMS1_k127_4424453_25	266264.Rmet_2802	1.79e-06	59.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,2VHEW@28216|Betaproteobacteria,1K2AG@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
CMS1_k127_4447350_4	1408433.JHXV01000043_gene3000	5.784e-21	102.0	COG2849@1|root,COG2849@2|Bacteria,4NMDX@976|Bacteroidetes,1I51X@117743|Flavobacteriia	976|Bacteroidetes	M	PFAM MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2,TPR_1,TPR_8
CMS1_k127_4447350_5	880070.Cycma_0178	3.737e-05	50.0	COG1621@1|root,COG1621@2|Bacteria,4P0AM@976|Bacteroidetes	976|Bacteroidetes	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4447350_0	344747.PM8797T_13048	3.596e-158	513.0	COG3119@1|root,COG3119@2|Bacteria,2IX0S@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
CMS1_k127_4447350_2	1120950.KB892761_gene5848	2.282e-98	338.0	COG4225@1|root,COG4225@2|Bacteria,2GJB5@201174|Actinobacteria	201174|Actinobacteria	S	BNR repeat-containing family member	-	-	-	-	-	-	-	-	-	-	-	-	BNR_4
CMS1_k127_4447350_3	1123242.JH636434_gene4911	9.09e-79	278.0	COG3356@1|root,COG3356@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
CMS1_k127_4447350_1	1123242.JH636436_gene642	2.202e-135	452.0	COG3119@1|root,COG3119@2|Bacteria,2IXG7@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS1_k127_4452334_5	903818.KI912268_gene1464	1.363e-106	361.0	COG0642@1|root,COG2205@2|Bacteria	903818.KI912268_gene1464|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4452334_3	1168034.FH5T_04505	1.469e-194	619.0	COG0502@1|root,COG0502@2|Bacteria,4NEI7@976|Bacteroidetes,2FM8N@200643|Bacteroidia	976|Bacteroidetes	C	In Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and IscS	hydG	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
CMS1_k127_4452334_7	338963.Pcar_2756	7.513e-27	113.0	2E5UQ@1|root,330IY@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4452334_1	335543.Sfum_1842	6.396e-213	670.0	COG1027@1|root,COG1027@2|Bacteria,1R9JY@1224|Proteobacteria,42MFS@68525|delta/epsilon subdivisions,2WJPR@28221|Deltaproteobacteria,2MRBH@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Fumarase C C-terminus	-	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	-	FumaraseC_C,Lyase_1
CMS1_k127_4452334_2	335543.Sfum_1843	1.643e-202	639.0	COG0486@1|root,COG0486@2|Bacteria,1PM94@1224|Proteobacteria,42MYX@68525|delta/epsilon subdivisions,2WJE4@28221|Deltaproteobacteria,2MR3V@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	50S ribosome-binding GTPase	hydF	-	-	-	-	-	-	-	-	-	-	-	MMR_HSR1
CMS1_k127_4452334_4	443143.GM18_1847	5.176e-148	476.0	COG0502@1|root,COG0502@2|Bacteria,1R8GT@1224|Proteobacteria,42QNT@68525|delta/epsilon subdivisions,2WN06@28221|Deltaproteobacteria,43T1U@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
CMS1_k127_4452334_6	203119.Cthe_0422	7.235e-42	166.0	COG2344@1|root,COG2344@2|Bacteria,1TSMR@1239|Firmicutes,247RQ@186801|Clostridia,3WJ49@541000|Ruminococcaceae	186801|Clostridia	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
CMS1_k127_4452334_8	243231.GSU0546	1.313e-24	108.0	COG1186@1|root,COG1186@2|Bacteria,1NBAD@1224|Proteobacteria,42UTT@68525|delta/epsilon subdivisions,2WQZK@28221|Deltaproteobacteria,43VGU@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	PFAM Class I peptide chain release factor	-	-	-	-	-	-	-	-	-	-	-	-	RF-1
CMS1_k127_4452334_0	240292.Ava_4099	2.504e-283	926.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1HIUT@1161|Nostocales	1117|Cyanobacteria	Q	TIGRFAM amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,NAD_binding_4,PP-binding,TPR_1,TPR_8,Thioesterase
CMS1_k127_4476471_8	443143.GM18_1115	4.463e-14	76.0	COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,42NPN@68525|delta/epsilon subdivisions,2WIY4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Belongs to the FPP GGPP synthase family	ispA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K00795,ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
CMS1_k127_4476471_6	1382306.JNIM01000001_gene2679	2.727e-25	108.0	COG3255@1|root,COG3255@2|Bacteria,2G7E8@200795|Chloroflexi	200795|Chloroflexi	I	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
CMS1_k127_4476471_9	1463881.KL591003_gene5663	1.486e-06	59.0	COG2936@1|root,COG2936@2|Bacteria,2I1ZG@201174|Actinobacteria	201174|Actinobacteria	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	PepX_C,Peptidase_S15
CMS1_k127_4476471_3	926550.CLDAP_35600	1.349e-52	203.0	COG1653@1|root,COG1653@2|Bacteria,2G8XC@200795|Chloroflexi	200795|Chloroflexi	G	COGs COG1653 ABC-type sugar transport system periplasmic component	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_8
CMS1_k127_4476471_1	411902.CLOBOL_06700	7.629e-70	249.0	COG0395@1|root,COG0395@2|Bacteria,1TRCP@1239|Firmicutes,249NY@186801|Clostridia,21Z67@1506553|Lachnoclostridium	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_4476471_2	1123389.ATXJ01000025_gene1113	3.912e-54	204.0	COG1175@1|root,COG1175@2|Bacteria,1WJ6F@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_4476471_0	351746.Pput_4800	7.217e-70	254.0	COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,1RNBR@1236|Gammaproteobacteria,1YWN9@136845|Pseudomonas putida group	1236|Gammaproteobacteria	M	glycosyl transferase group 1	waaA	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	iECNA114_1301.ECNA114_3778,iUMNK88_1353.UMNK88_4417	Glycos_transf_1,Glycos_transf_N
CMS1_k127_4476471_7	595494.Tola_2627	1.297e-22	115.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,1RN3Z@1236|Gammaproteobacteria,1Y3NV@135624|Aeromonadales	135624|Aeromonadales	U	type IV pilus secretin PilQ	-	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
CMS1_k127_4476471_5	349741.Amuc_1101	3.164e-32	145.0	COG4972@1|root,COG4972@2|Bacteria,46UI7@74201|Verrucomicrobia,2ITTF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	NU	Type IV pilus assembly protein PilM;	-	-	-	-	-	-	-	-	-	-	-	-	PilM_2
CMS1_k127_4476471_4	616991.JPOO01000003_gene2394	2.069e-47	188.0	COG1262@1|root,COG1262@2|Bacteria,4NGBN@976|Bacteroidetes	976|Bacteroidetes	S	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
CMS1_k127_4477667_0	1142394.PSMK_27520	1.277e-45	168.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	FGE-sulfatase
CMS1_k127_4477667_1	768671.ThimaDRAFT_4451	4.02e-05	49.0	COG1100@1|root,COG1262@1|root,COG1100@2|Bacteria,COG1262@2|Bacteria,1QH0S@1224|Proteobacteria,1SEPT@1236|Gammaproteobacteria,1X2W3@135613|Chromatiales	135613|Chromatiales	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
CMS1_k127_4481092_1	344747.PM8797T_18811	4.827e-52	196.0	2CEKM@1|root,2ZM0S@2|Bacteria,2J4EH@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4481092_0	502025.Hoch_4658	4.576e-93	318.0	COG1858@1|root,COG3420@1|root,COG1858@2|Bacteria,COG3420@2|Bacteria,1MV70@1224|Proteobacteria,42ZVA@68525|delta/epsilon subdivisions,2WVEX@28221|Deltaproteobacteria,2YU4Z@29|Myxococcales	28221|Deltaproteobacteria	C	cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG
CMS1_k127_4494557_3	1089550.ATTH01000001_gene1127	1.957e-32	130.0	2DBQR@1|root,2ZAG2@2|Bacteria,4NK84@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2
CMS1_k127_4494557_5	243090.RB1862	1.357e-20	96.0	COG1725@1|root,COG1725@2|Bacteria,2J0ST@203682|Planctomycetes	203682|Planctomycetes	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
CMS1_k127_4494557_0	497964.CfE428DRAFT_3698	2.696e-148	486.0	COG1621@1|root,COG1621@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 32 family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,HTH_18
CMS1_k127_4494557_7	694431.DESACE_05140	0.0007327	51.0	COG0810@1|root,COG0810@2|Bacteria,1R330@1224|Proteobacteria,437DK@68525|delta/epsilon subdivisions,2WSN1@28221|Deltaproteobacteria,2M76S@213113|Desulfurellales	28221|Deltaproteobacteria	M	TonB C terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
CMS1_k127_4494557_1	1499967.BAYZ01000028_gene1348	7.687e-79	281.0	COG0823@1|root,COG0823@2|Bacteria,2NNZC@2323|unclassified Bacteria	2|Bacteria	U	TolB amino-terminal domain	tolB	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019534,GO:0019904,GO:0022857,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901998	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
CMS1_k127_4494557_2	1121468.AUBR01000008_gene2068	1.181e-51	187.0	COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,24HD6@186801|Clostridia,42GC6@68295|Thermoanaerobacterales	186801|Clostridia	J	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
CMS1_k127_4494557_4	1396141.BATP01000020_gene90	4.576e-32	129.0	COG1695@1|root,COG1695@2|Bacteria,46WGD@74201|Verrucomicrobia,2IW9N@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
CMS1_k127_4494557_6	1345695.CLSA_c37610	7.516e-11	71.0	COG4219@1|root,COG4219@2|Bacteria,1TP3Z@1239|Firmicutes,249NV@186801|Clostridia,36HDP@31979|Clostridiaceae	186801|Clostridia	KT	Peptidase, M56	blaR	-	-	ko:K02172	ko01501,map01501	M00627	-	-	ko00000,ko00001,ko00002,ko01002,ko01504	-	-	-	NAGPA,Peptidase_M56
CMS1_k127_4497493_2	1219084.AP014508_gene426	2.78e-15	81.0	arCOG03622@1|root,33HZF@2|Bacteria,2GE37@200918|Thermotogae	200918|Thermotogae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4497493_0	697281.Mahau_1208	1.281e-135	441.0	COG0407@1|root,COG0407@2|Bacteria,1UY51@1239|Firmicutes,24DZF@186801|Clostridia,42FW9@68295|Thermoanaerobacterales	186801|Clostridia	H	PFAM Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
CMS1_k127_4497493_3	933262.AXAM01000031_gene3004	4.869e-06	49.0	COG1943@1|root,COG1943@2|Bacteria,1P19I@1224|Proteobacteria,42PP3@68525|delta/epsilon subdivisions,2WK0G@28221|Deltaproteobacteria,2MJPT@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
CMS1_k127_4497493_1	1444712.BN1013_02040	2.618e-85	304.0	COG3356@1|root,COG3356@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
CMS1_k127_4502928_9	1226325.HMPREF1548_02230	1.365e-129	436.0	COG3525@1|root,COG3525@2|Bacteria	2|Bacteria	G	beta-N-acetylhexosaminidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4838,F5_F8_type_C,Glyco_hydro_67N
CMS1_k127_4502928_4	44056.XP_009033642.1	6.944e-175	561.0	COG0160@1|root,KOG1403@2759|Eukaryota	2759|Eukaryota	E	ethanolamine-phosphate phospho-lyase activity	-	-	4.2.3.2	ko:K14286	ko00564,ko01100,map00564,map01100	-	R00748	RC00369	ko00000,ko00001,ko01000	-	-	-	Aminotran_3,Peptidase_M23
CMS1_k127_4502928_19	1054213.HMPREF9946_02541	2.593e-82	289.0	COG0657@1|root,COG0657@2|Bacteria,1RD8A@1224|Proteobacteria,2U1B8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Alpha beta hydrolase	-	-	3.1.1.83	ko:K14731	ko00903,ko00930,ko01220,map00903,map00930,map01220	-	R03751,R06390,R06391,R06392,R06393	RC00713,RC00983,RC01505	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_3
CMS1_k127_4502928_3	112098.XP_008607965.1	1.671e-189	613.0	COG1372@1|root,2QRRC@2759|Eukaryota	2759|Eukaryota	L	reductase	-	GO:0003674,GO:0003824,GO:0004748,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009141,GO:0009142,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	-	-	-	-	-	-	-	-	-	-	Ribonuc_red_lgC
CMS1_k127_4502928_21	671143.DAMO_1621	4.496e-77	265.0	COG1351@1|root,COG1351@2|Bacteria	2|Bacteria	F	thymidylate synthase (FAD) activity	thyX	GO:0000166,GO:0003674,GO:0003824,GO:0004799,GO:0005488,GO:0008150,GO:0008152,GO:0008168,GO:0016740,GO:0016741,GO:0032259,GO:0036094,GO:0040007,GO:0042083,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050797,GO:0070402,GO:0097159,GO:1901265,GO:1901363	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	iNJ661.Rv2754c	Thy1
CMS1_k127_4502928_30	661478.OP10G_0619	2.491e-32	144.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H,Bac_rhamnosid_C,DUF1501,Sulfatase
CMS1_k127_4502928_22	593750.Metfor_0263	1.956e-76	282.0	COG1269@1|root,arCOG04138@2157|Archaea,2XTQP@28890|Euryarchaeota,2NAKS@224756|Methanomicrobia	224756|Methanomicrobia	C	V-type ATPase 116kDa subunit family	atpI-2	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
CMS1_k127_4502928_38	593750.Metfor_0254	2.051e-07	57.0	COG0636@1|root,arCOG02455@2157|Archaea,2Y4F6@28890|Euryarchaeota,2NB8I@224756|Methanomicrobia	224756|Methanomicrobia	C	ATP synthase subunit C	atpK-2	-	-	ko:K02124	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_C
CMS1_k127_4502928_39	604331.AUHY01000012_gene2732	0.0002104	51.0	COG1390@1|root,COG1390@2|Bacteria,1WK58@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpE	-	-	ko:K02121	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_E
CMS1_k127_4502928_31	1041930.Mtc_2336	3.53e-32	141.0	COG1527@1|root,arCOG02459@2157|Archaea,2XTK5@28890|Euryarchaeota,2NAIS@224756|Methanomicrobia	224756|Methanomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC-2	-	-	ko:K02119	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_AC39
CMS1_k127_4502928_1	1041930.Mtc_2334	6.027e-207	659.0	COG1155@1|root,arCOG00868@2157|Archaea,2XT8I@28890|Euryarchaeota,2NANC@224756|Methanomicrobia	224756|Methanomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit	atpA-2	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
CMS1_k127_4502928_2	869210.Marky_1599	7.798e-192	609.0	COG1156@1|root,COG1156@2|Bacteria,1WIDT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	atpB	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
CMS1_k127_4502928_32	1123389.ATXJ01000002_gene1610	6.634e-29	124.0	COG1394@1|root,COG1394@2|Bacteria,1WJXJ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpD	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
CMS1_k127_4502928_33	1396141.BATP01000005_gene6062	5.206e-21	99.0	COG1762@1|root,COG1762@2|Bacteria,46VMP@74201|Verrucomicrobia,2IUWS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	GT	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	-	-	-	-	-	-	-	-	-	-	-	-	PTS_EIIA_2
CMS1_k127_4502928_36	525909.Afer_1452	4.507e-15	82.0	COG1959@1|root,COG1959@2|Bacteria,2GS0E@201174|Actinobacteria,4CNRF@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
CMS1_k127_4502928_34	583355.Caka_0066	1.188e-20	100.0	28JYU@1|root,2Z9NZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Cytochrome_C7,Paired_CXXCH_1
CMS1_k127_4502928_13	1403819.BATR01000094_gene3012	9.348e-106	352.0	COG0437@1|root,COG0437@2|Bacteria,46UV0@74201|Verrucomicrobia,2IU11@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_11
CMS1_k127_4502928_8	583355.Caka_0068	4.864e-142	463.0	COG5557@1|root,COG5557@2|Bacteria	2|Bacteria	C	Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
CMS1_k127_4502928_24	1232410.KI421424_gene1761	5.156e-68	254.0	2EXQK@1|root,33R03@2|Bacteria,1NQU4@1224|Proteobacteria,42Y7S@68525|delta/epsilon subdivisions,2WTT3@28221|Deltaproteobacteria,43UGY@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4502928_15	445335.CBN_0643	7.937e-96	329.0	COG1972@1|root,COG1972@2|Bacteria,1TRSK@1239|Firmicutes,249IZ@186801|Clostridia,36FNG@31979|Clostridiaceae	186801|Clostridia	F	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family	-	-	-	ko:K03317	-	-	-	-	ko00000	2.A.41	-	-	Gate,Nucleos_tra2_C,Nucleos_tra2_N
CMS1_k127_4502928_16	608538.HTH_1167	2.319e-93	313.0	COG0351@1|root,COG0351@2|Bacteria,2G4ME@200783|Aquificae	200783|Aquificae	H	Phosphomethylpyrimidine kinase	-	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
CMS1_k127_4502928_25	452637.Oter_0043	6.404e-68	241.0	COG2197@1|root,COG2197@2|Bacteria,46V5Z@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS1_k127_4502928_27	1267533.KB906737_gene1727	2.249e-66	252.0	COG2202@1|root,COG4585@1|root,COG2202@2|Bacteria,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07675	ko02020,map02020	M00473	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA_3,MASE1,PAS,PAS_3,PAS_4,PAS_9,Peripla_BP_3,Response_reg,dCache_2
CMS1_k127_4502928_35	517417.Cpar_1325	3.743e-20	106.0	COG0784@1|root,COG2202@1|root,COG2203@1|root,COG3829@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1FEG0@1090|Chlorobi	1090|Chlorobi	T	SMART PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_9,Response_reg
CMS1_k127_4502928_10	483219.LILAB_01095	1.368e-115	381.0	COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,42M0C@68525|delta/epsilon subdivisions,2WMJ2@28221|Deltaproteobacteria,2YY0V@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
CMS1_k127_4502928_11	1209989.TepiRe1_0363	4.346e-114	385.0	COG0168@1|root,COG0168@2|Bacteria,1TPAF@1239|Firmicutes,248K4@186801|Clostridia,42GHF@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM cation transporter	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
CMS1_k127_4502928_12	1304874.JAFY01000005_gene1299	2.227e-110	380.0	COG0168@1|root,COG0168@2|Bacteria,3T9WI@508458|Synergistetes	508458|Synergistetes	P	Potassium uptake protein, TrkH family	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
CMS1_k127_4502928_18	1293047.CBMA010000028_gene1905	5.398e-91	310.0	COG0604@1|root,arCOG01458@2157|Archaea,2XU74@28890|Euryarchaeota,23T36@183963|Halobacteria	183963|Halobacteria	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	qor2	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_4502928_26	644282.Deba_2660	4.072e-67	236.0	COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,42R4A@68525|delta/epsilon subdivisions,2WM9Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM Silent information regulator protein Sir2	-	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
CMS1_k127_4502928_5	269799.Gmet_3528	1.936e-163	527.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,42M7H@68525|delta/epsilon subdivisions,2WIT7@28221|Deltaproteobacteria,43SZ2@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF987.Gmet_3528	Seryl_tRNA_N,tRNA-synt_2b
CMS1_k127_4502928_28	1408436.JHXY01000019_gene1422	8.569e-66	235.0	COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,249VV@186801|Clostridia,25UXZ@186806|Eubacteriaceae	186801|Clostridia	K	Belongs to the ParB family	spo0J	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
CMS1_k127_4502928_17	562970.Btus_3315	3.877e-91	307.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,4HAYM@91061|Bacilli,278T5@186823|Alicyclobacillaceae	91061|Bacilli	D	Cellulose biosynthesis protein BcsQ	soj	GO:0008150,GO:0022603,GO:0042173,GO:0042174,GO:0043937,GO:0043939,GO:0045595,GO:0045596,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0065007	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
CMS1_k127_4502928_37	313596.RB2501_09775	4.639e-11	70.0	294EW@1|root,2ZRUR@2|Bacteria,4NPA3@976|Bacteroidetes,1I38U@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1569)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1569
CMS1_k127_4502928_20	871968.DESME_13845	5.008e-81	284.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,2483J@186801|Clostridia,260DV@186807|Peptococcaceae	186801|Clostridia	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS1_k127_4502928_29	795797.C497_00325	2.172e-42	165.0	COG0569@1|root,arCOG01957@2157|Archaea,2Y86Y@28890|Euryarchaeota,23TKA@183963|Halobacteria	183963|Halobacteria	P	COG0569 K transport systems, NAD-binding component	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
CMS1_k127_4502928_6	32057.KB217478_gene6750	3.029e-162	525.0	COG0168@1|root,COG0168@2|Bacteria,1G2VM@1117|Cyanobacteria,1HP3H@1161|Nostocales	1117|Cyanobacteria	P	Cation transport protein	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
CMS1_k127_4502928_7	290397.Adeh_1499	1.316e-153	500.0	COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,42M6I@68525|delta/epsilon subdivisions,2WJTV@28221|Deltaproteobacteria,2YU3G@29|Myxococcales	28221|Deltaproteobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_1886	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
CMS1_k127_4502928_23	574087.Acear_1783	2.868e-76	264.0	COG0294@1|root,COG0294@2|Bacteria,1TPKT@1239|Firmicutes,248BE@186801|Clostridia,3WBAE@53433|Halanaerobiales	186801|Clostridia	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS03115	Pterin_bind
CMS1_k127_4502928_0	269799.Gmet_1890	5.308e-215	685.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2WJ0D@28221|Deltaproteobacteria,43U9K@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
CMS1_k127_4502928_14	661478.OP10G_0957	3.075e-99	335.0	COG0836@1|root,COG0836@2|Bacteria	2|Bacteria	M	mannose-1-phosphate guanylyltransferase activity	manC	-	2.7.7.13,5.3.1.8,5.4.2.8	ko:K00971,ko:K01840,ko:K16011	ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025	M00114,M00361,M00362	R00885,R01818,R01819	RC00002,RC00376,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS00940	MannoseP_isomer,NTP_transferase
CMS1_k127_4504192_21	1121904.ARBP01000052_gene3651	1.112e-10	64.0	COG1501@1|root,COG1501@2|Bacteria,4NH0T@976|Bacteroidetes,47TMI@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolases family 31	-	-	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	Glyco_hydro_31
CMS1_k127_4504192_11	1379698.RBG1_1C00001G0503	2.083e-43	180.0	COG1807@1|root,COG1807@2|Bacteria,2NP0P@2323|unclassified Bacteria	2|Bacteria	M	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT_2
CMS1_k127_4504192_17	714943.Mucpa_0627	1.953e-24	108.0	COG0346@1|root,COG0346@2|Bacteria,4P38T@976|Bacteroidetes	976|Bacteroidetes	C	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS1_k127_4504192_10	1499967.BAYZ01000118_gene3301	5.372e-45	169.0	COG1359@1|root,COG1359@2|Bacteria	2|Bacteria	S	Antibiotic biosynthesis monooxygenase	lsrG	-	5.3.1.32	ko:K11530	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000	-	-	-	ABM
CMS1_k127_4504192_13	1304885.AUEY01000003_gene509	2.084e-31	132.0	COG0780@1|root,COG0780@2|Bacteria,1MW0M@1224|Proteobacteria,42RDZ@68525|delta/epsilon subdivisions,2WQ4Z@28221|Deltaproteobacteria,2MK4R@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K06879,ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
CMS1_k127_4504192_16	1214065.BAGV01000038_gene486	4.451e-27	119.0	COG0720@1|root,COG0720@2|Bacteria,1RI4P@1224|Proteobacteria,1S3T6@1236|Gammaproteobacteria,283EQ@191675|unclassified Enterobacteriaceae	1236|Gammaproteobacteria	H	6-pyruvoyl tetrahydropterin synthase	queD	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0070497,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	iECIAI39_1322.ECIAI39_2947,iUTI89_1310.UTI89_C3129,ic_1306.c3324	PTPS
CMS1_k127_4504192_18	1278073.MYSTI_05528	1.744e-20	100.0	COG0720@1|root,COG0720@2|Bacteria,1RI4P@1224|Proteobacteria,437K2@68525|delta/epsilon subdivisions,2WW0X@28221|Deltaproteobacteria,2YVI7@29|Myxococcales	28221|Deltaproteobacteria	H	6-pyruvoyl tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
CMS1_k127_4504192_6	330214.NIDE0244	9.284e-77	263.0	COG0602@1|root,COG0602@2|Bacteria,3J0M2@40117|Nitrospirae	40117|Nitrospirae	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
CMS1_k127_4504192_1	595460.RRSWK_05487	5.009e-118	389.0	COG1621@1|root,COG1621@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 32 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43,Sulfatase
CMS1_k127_4504192_0	1286632.P278_29940	1.584e-177	571.0	COG3119@1|root,COG3119@2|Bacteria,4NEFN@976|Bacteroidetes,1HYF8@117743|Flavobacteriia	976|Bacteroidetes	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	DUF4994,Sulfatase
CMS1_k127_4504192_4	1396141.BATP01000040_gene2101	4.395e-90	320.0	COG5267@1|root,COG5267@2|Bacteria,46SWV@74201|Verrucomicrobia,2IVM0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
CMS1_k127_4504192_3	1210884.HG799465_gene11413	1.064e-96	331.0	COG4102@1|root,COG4102@2|Bacteria,2IYGM@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CMS1_k127_4504192_5	234267.Acid_4616	1.428e-81	284.0	COG2199@1|root,COG3706@2|Bacteria,3Y4ZC@57723|Acidobacteria	57723|Acidobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
CMS1_k127_4504192_7	1303518.CCALI_02640	5.198e-65	235.0	COG5285@1|root,COG5285@2|Bacteria	2|Bacteria	Q	dioxygenase activity	-	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016705,GO:0016706,GO:0016999,GO:0017000,GO:0017144,GO:0018130,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0046483,GO:0046872,GO:0046914,GO:0051213,GO:0055114,GO:0071704,GO:1901334,GO:1901336,GO:1901360,GO:1901362,GO:1901576	1.14.11.35	ko:K18056	ko01130,map01130	M00819	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	PhyH
CMS1_k127_4504192_9	450851.PHZ_c3138	1.834e-57	207.0	COG0740@1|root,COG0740@2|Bacteria,1RBNX@1224|Proteobacteria,2U5ZH@28211|Alphaproteobacteria,2KIMN@204458|Caulobacterales	204458|Caulobacterales	OU	Clp protease	-	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
CMS1_k127_4504192_8	344747.PM8797T_17237	1.202e-59	219.0	COG0657@1|root,COG0657@2|Bacteria,2IYY7@203682|Planctomycetes	203682|Planctomycetes	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
CMS1_k127_4504192_15	1906.SFRA_06835	1.062e-27	120.0	COG1595@1|root,COG1595@2|Bacteria,2IHWH@201174|Actinobacteria	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS1_k127_4504192_14	203122.Sde_0095	7.701e-31	128.0	COG1595@1|root,COG1595@2|Bacteria,1RIU9@1224|Proteobacteria,1SAMD@1236|Gammaproteobacteria,469AD@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_4504192_2	1210884.HG799462_gene8853	8.559e-104	351.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
CMS1_k127_4504192_19	518766.Rmar_2641	6.612e-17	86.0	COG3682@1|root,COG3682@2|Bacteria,4P9FT@976|Bacteroidetes,1FJNX@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
CMS1_k127_4504192_12	886293.Sinac_0185	3.051e-33	137.0	COG1595@1|root,COG1595@2|Bacteria,2IZH8@203682|Planctomycetes	203682|Planctomycetes	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Abhydrolase_2
CMS1_k127_4504192_20	234267.Acid_5553	6.337e-12	75.0	COG4219@1|root,COG4219@2|Bacteria,3Y4QS@57723|Acidobacteria	57723|Acidobacteria	KT	Peptidase M56, BlaR1	-	-	-	-	-	-	-	-	-	-	-	-	DUF3738,Peptidase_M56
CMS1_k127_450940_7	608506.COB47_1856	7.672e-05	54.0	COG2755@1|root,COG2755@2|Bacteria,1VJFT@1239|Firmicutes	1239|Firmicutes	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS1_k127_450940_5	1120949.KB903324_gene3346	5.23e-30	134.0	COG4030@1|root,COG4030@2|Bacteria,2GJFD@201174|Actinobacteria,4DCCD@85008|Micromonosporales	201174|Actinobacteria	S	Protein of unknown function (DUF2961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
CMS1_k127_450940_1	742738.HMPREF9460_00523	7.604e-89	304.0	COG0673@1|root,COG0673@2|Bacteria,1TQ72@1239|Firmicutes,24NIH@186801|Clostridia,269X0@186813|unclassified Clostridiales	186801|Clostridia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_450940_6	525904.Tter_2163	1.206e-13	78.0	arCOG07473@1|root,33M4W@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_450940_2	861299.J421_2232	2.848e-49	192.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_450940_4	667014.Thein_1316	6.063e-31	137.0	COG2199@1|root,COG3706@2|Bacteria,2GGYZ@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
CMS1_k127_450940_3	1321786.HMPREF1992_01465	1.095e-45	173.0	COG0279@1|root,COG0279@2|Bacteria,1V5W5@1239|Firmicutes	1239|Firmicutes	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
CMS1_k127_450940_0	313628.LNTAR_18720	1.508e-132	428.0	COG1915@1|root,COG1915@2|Bacteria	2|Bacteria	E	PFAM LOR SDH bifunctional enzyme conserved region	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4512814_2	237368.SCABRO_03982	2.488e-11	70.0	COG1943@1|root,COG1943@2|Bacteria,2IYXS@203682|Planctomycetes	203682|Planctomycetes	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
CMS1_k127_4512814_1	86416.Clopa_3045	3.269e-44	172.0	COG1682@1|root,COG1682@2|Bacteria,1TY8I@1239|Firmicutes,25B42@186801|Clostridia,36W8R@31979|Clostridiaceae	186801|Clostridia	U	Transport permease protein	-	-	-	ko:K01992,ko:K09690	ko02010,map02010	M00250,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.103	-	-	ABC2_membrane
CMS1_k127_4512814_0	1047013.AQSP01000144_gene865	1.912e-68	250.0	COG1134@1|root,COG1134@2|Bacteria,2NP4S@2323|unclassified Bacteria	2|Bacteria	GM	ATPases associated with a variety of cellular activities	-	-	3.6.3.38	ko:K01990,ko:K09689,ko:K09691	ko02010,map02010	M00249,M00250,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.101,3.A.1.103	-	-	ABC_tran,Wzt_C
CMS1_k127_4519655_2	344747.PM8797T_26350	2.087e-63	230.0	COG2010@1|root,COG2010@2|Bacteria,2IYZK@203682|Planctomycetes	203682|Planctomycetes	C	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CMS1_k127_4519655_1	1499967.BAYZ01000017_gene6259	3.434e-73	255.0	COG1215@1|root,COG1215@2|Bacteria,2NPW4@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS1_k127_4519655_0	452637.Oter_3515	1.757e-86	306.0	COG4745@1|root,COG4745@2|Bacteria,46T45@74201|Verrucomicrobia,3K9I6@414999|Opitutae	414999|Opitutae	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS1_k127_4519655_3	452637.Oter_3514	1.845e-50	182.0	2F286@1|root,33V6C@2|Bacteria,46V8R@74201|Verrucomicrobia,3K9H5@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4527581_0	518766.Rmar_1568	6.8e-163	530.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,4NECB@976|Bacteroidetes,1FISZ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
CMS1_k127_4527581_1	398767.Glov_1382	6.134e-44	162.0	COG1996@1|root,COG1996@2|Bacteria,1QV33@1224|Proteobacteria,43CNA@68525|delta/epsilon subdivisions,2X7VK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4529070_2	452637.Oter_2238	4.157e-70	242.0	COG0441@1|root,COG0572@1|root,COG0441@2|Bacteria,COG0572@2|Bacteria	2|Bacteria	F	uridine kinase	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
CMS1_k127_4529070_0	926569.ANT_22140	2.314e-99	329.0	COG0479@1|root,COG0479@2|Bacteria,2G659@200795|Chloroflexi	200795|Chloroflexi	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_10,Fer4_8
CMS1_k127_4529070_1	68219.JNXI01000016_gene6871	2.098e-92	310.0	COG1053@1|root,COG1053@2|Bacteria,2GJ45@201174|Actinobacteria	201174|Actinobacteria	C	succinate dehydrogenase	sdhA	GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363	1.3.5.1,1.3.5.4,1.4.3.16	ko:K00239,ko:K00278	ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00115,M00149,M00173,M00374,M00376	R00357,R00481,R02164	RC00006,RC00045,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
CMS1_k127_4539811_0	1408254.T458_02875	1.447e-60	221.0	COG2267@1|root,COG2267@2|Bacteria,1V0IY@1239|Firmicutes,4HBP3@91061|Bacilli,26T7K@186822|Paenibacillaceae	91061|Bacilli	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
CMS1_k127_4539811_2	543632.JOJL01000012_gene6673	7.824e-20	95.0	COG1917@1|root,COG1917@2|Bacteria,2IRRU@201174|Actinobacteria,4DJUR@85008|Micromonosporales	201174|Actinobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4539811_1	1499967.BAYZ01000116_gene3146	9.359e-25	110.0	2EEHS@1|root,338BM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4542346_0	502025.Hoch_1047	6.304e-131	432.0	COG3547@1|root,COG3547@2|Bacteria,1MUKH@1224|Proteobacteria,42NNJ@68525|delta/epsilon subdivisions,2WKP9@28221|Deltaproteobacteria,2YXSD@29|Myxococcales	28221|Deltaproteobacteria	L	PFAM transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,DUF2924,Transposase_20
CMS1_k127_454483_1	344747.PM8797T_20583	1.254e-209	657.0	COG3119@1|root,COG3119@2|Bacteria,2IX0S@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS1_k127_454483_19	530564.Psta_3759	7.65e-62	228.0	COG2010@1|root,COG2010@2|Bacteria,2IZQX@203682|Planctomycetes	203682|Planctomycetes	C	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CMS1_k127_454483_30	1224163.B841_01610	1.616e-19	89.0	COG1278@1|root,COG1278@2|Bacteria,2GQRU@201174|Actinobacteria,22NT6@1653|Corynebacteriaceae	201174|Actinobacteria	K	Cold shock proteins	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
CMS1_k127_454483_4	1123242.JH636435_gene2295	7.617e-178	568.0	COG3119@1|root,COG3119@2|Bacteria,2J1XV@203682|Planctomycetes	203682|Planctomycetes	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS1_k127_454483_16	720554.Clocl_2251	7.811e-74	255.0	COG0177@1|root,COG0177@2|Bacteria,1TRAK@1239|Firmicutes,24899@186801|Clostridia,3WGWR@541000|Ruminococcaceae	186801|Clostridia	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
CMS1_k127_454483_2	403833.Pmob_0486	9.986e-209	663.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,2GE9T@200918|Thermotogae	200918|Thermotogae	L	DNA polymerase alpha chain like domain	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	PHP
CMS1_k127_454483_0	237368.SCABRO_03786	2.24e-273	863.0	COG0466@1|root,COG0466@2|Bacteria,2IYNA@203682|Planctomycetes	203682|Planctomycetes	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
CMS1_k127_454483_31	1396418.BATQ01000181_gene825	1.385e-15	83.0	COG0071@1|root,COG0071@2|Bacteria	2|Bacteria	O	Belongs to the small heat shock protein (HSP20) family	hspA	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
CMS1_k127_454483_25	1392502.JNIO01000008_gene2295	3.568e-34	140.0	COG1496@1|root,COG1496@2|Bacteria,1TS34@1239|Firmicutes,4H26Q@909932|Negativicutes	909932|Negativicutes	S	Belongs to the multicopper oxidase YfiH RL5 family	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
CMS1_k127_454483_5	880073.Calab_0163	6.804e-167	537.0	COG1220@1|root,COG1220@2|Bacteria,2NP00@2323|unclassified Bacteria	2|Bacteria	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019904,GO:0022607,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043335,GO:0043933,GO:0044085,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1904949,GO:1905368,GO:1905369	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
CMS1_k127_454483_22	203119.Cthe_2597	4.059e-44	165.0	COG0698@1|root,COG0698@2|Bacteria,1V3HE@1239|Firmicutes,24JWT@186801|Clostridia,3WJA1@541000|Ruminococcaceae	186801|Clostridia	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
CMS1_k127_454483_27	477974.Daud_2151	5.166e-31	130.0	COG0009@1|root,COG0009@2|Bacteria,1TP1I@1239|Firmicutes,248HS@186801|Clostridia,26028@186807|Peptococcaceae	186801|Clostridia	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	sua	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
CMS1_k127_454483_21	643648.Slip_2049	9.786e-52	190.0	COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,249GK@186801|Clostridia,42JZF@68298|Syntrophomonadaceae	186801|Clostridia	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
CMS1_k127_454483_14	391615.ABSJ01000023_gene357	8.345e-85	287.0	COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,1RNTB@1236|Gammaproteobacteria,1J4ME@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
CMS1_k127_454483_15	1123371.ATXH01000002_gene333	5.448e-74	268.0	COG0793@1|root,COG0793@2|Bacteria,2GH5D@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
CMS1_k127_454483_32	237368.SCABRO_03851	3.704e-15	87.0	COG2165@1|root,COG2165@2|Bacteria,2J0Q6@203682|Planctomycetes	203682|Planctomycetes	U	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CMS1_k127_454483_9	1395571.TMS3_0103995	8.392e-125	410.0	COG0596@1|root,COG0596@2|Bacteria,1MUSF@1224|Proteobacteria,1RP4C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons	dhmA	-	3.8.1.5	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS1_k127_454483_23	404589.Anae109_1138	2.405e-37	146.0	COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,42THF@68525|delta/epsilon subdivisions,2WQ0W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
CMS1_k127_454483_11	264732.Moth_1047	6.966e-110	368.0	COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,247W8@186801|Clostridia,42EQU@68295|Thermoanaerobacterales	186801|Clostridia	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
CMS1_k127_454483_3	717605.Theco_2057	4.143e-190	627.0	COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,4HA8S@91061|Bacilli,26RD4@186822|Paenibacillaceae	91061|Bacilli	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
CMS1_k127_454483_35	639030.JHVA01000001_gene1510	7.75e-14	76.0	COG1550@1|root,COG1550@2|Bacteria,3Y5B8@57723|Acidobacteria,2JJUV@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF503)	-	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
CMS1_k127_454483_28	1120973.AQXL01000128_gene2810	1.565e-29	121.0	COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,4HII1@91061|Bacilli,278JM@186823|Alicyclobacillaceae	91061|Bacilli	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
CMS1_k127_454483_20	555088.DealDRAFT_2420	1.387e-61	225.0	COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,248R3@186801|Clostridia,42JWN@68298|Syntrophomonadaceae	186801|Clostridia	S	DHH family	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
CMS1_k127_454483_17	671143.DAMO_0578	3.623e-70	248.0	COG0130@1|root,COG0130@2|Bacteria,2NP9J@2323|unclassified Bacteria	2|Bacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0000049,GO:0001522,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0031119,GO:0034337,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C_2,TruB_N
CMS1_k127_454483_18	335543.Sfum_3182	3.067e-69	246.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,42MV7@68525|delta/epsilon subdivisions,2WJTU@28221|Deltaproteobacteria,2MQCP@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
CMS1_k127_454483_10	240016.ABIZ01000001_gene5154	3.684e-123	418.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	OEP
CMS1_k127_454483_12	240016.ABIZ01000001_gene5155	6.202e-108	375.0	COG0845@1|root,COG0845@2|Bacteria,46WF0@74201|Verrucomicrobia	74201|Verrucomicrobia	M	HlyD family secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3,HlyD_D23
CMS1_k127_454483_13	1403819.BATR01000070_gene2105	1.762e-92	308.0	COG1136@1|root,COG1136@2|Bacteria,46SI5@74201|Verrucomicrobia,2IUA4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_454483_6	1396418.BATQ01000030_gene5614	2.653e-144	471.0	COG0577@1|root,COG0577@2|Bacteria,46TQS@74201|Verrucomicrobia,2IWMB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
CMS1_k127_454483_29	448385.sce4162	7.802e-22	109.0	COG4552@1|root,COG4552@2|Bacteria	2|Bacteria	S	transferase activity, transferring acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_9,SCP2_2
CMS1_k127_454483_8	382464.ABSI01000010_gene3519	1.022e-128	420.0	COG1621@1|root,COG1621@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 32 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_32N,Glyco_hydro_43
CMS1_k127_454483_34	10224.XP_002739137.1	5.308e-14	83.0	2CMYA@1|root,2QSQ7@2759|Eukaryota,39NEH@33154|Opisthokonta,3BZE1@33208|Metazoa,3DDH7@33213|Bilateria	2759|Eukaryota	S	Endonuclease/Exonuclease/phosphatase family	-	-	3.1.4.12	ko:K01117	ko00600,ko01100,map00600,map01100	-	R02541	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	Exo_endo_phos
CMS1_k127_454483_26	1068978.AMETH_6139	6.731e-32	142.0	COG2159@1|root,COG2159@2|Bacteria,2I967@201174|Actinobacteria	201174|Actinobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
CMS1_k127_454483_36	1121441.AUCX01000006_gene877	0.0009976	49.0	2AHQC@1|root,3182J@2|Bacteria,1PZQ0@1224|Proteobacteria,43634@68525|delta/epsilon subdivisions,2X0M0@28221|Deltaproteobacteria,2MCS5@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_454483_24	1307759.JOMJ01000003_gene48	2.117e-35	146.0	COG1639@1|root,COG1639@2|Bacteria,1R8H3@1224|Proteobacteria,42PER@68525|delta/epsilon subdivisions,2WKZ5@28221|Deltaproteobacteria,2M7T7@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM Metal-dependent hydrolase HDOD	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
CMS1_k127_454483_7	1121904.ARBP01000015_gene173	2.589e-132	435.0	COG0673@1|root,COG0673@2|Bacteria,4NGHJ@976|Bacteroidetes,47K7H@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_454483_33	1396141.BATP01000002_gene4837	1.449e-14	79.0	COG3828@1|root,COG3828@2|Bacteria,46V1D@74201|Verrucomicrobia,2IUS0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
CMS1_k127_4548587_1	211114.JOEF01000003_gene2782	4.352e-13	82.0	COG3250@1|root,COG3250@2|Bacteria,2GMAT@201174|Actinobacteria,4DZUE@85010|Pseudonocardiales	201174|Actinobacteria	G	Beta galactosidase small chain	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Laminin_G_3,NPCBM,NPCBM_assoc
CMS1_k127_4548587_0	1229909.NSED_01725	9.719e-29	126.0	COG3979@1|root,COG5549@1|root,arCOG04994@2157|Archaea,arCOG07581@2157|Archaea	2157|Archaea	C	PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	AstE_AspA,PKD,PQQ_2
CMS1_k127_4550902_14	1120956.JHZK01000009_gene1708	8.157e-17	86.0	COG0500@1|root,COG2226@2|Bacteria,1QYDX@1224|Proteobacteria,2TXQ0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
CMS1_k127_4550902_10	521011.Mpal_1783	3.222e-44	179.0	COG3291@1|root,arCOG02559@1|root,arCOG02508@2157|Archaea,arCOG02510@2157|Archaea,arCOG02559@2157|Archaea	2157|Archaea	P	by modhmm	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,NosD,PKD,SBBP
CMS1_k127_4550902_6	1131269.AQVV01000001_gene1406	4.234e-105	363.0	COG0404@1|root,COG0457@1|root,COG3071@1|root,COG0404@2|Bacteria,COG0457@2|Bacteria,COG3071@2|Bacteria	2|Bacteria	H	HemY protein	ygfZ	-	1.5.3.1,2.1.2.10,3.1.21.3	ko:K00305,ko:K00605,ko:K01153,ko:K02498,ko:K06980	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R00610,R01221,R02300,R04125	RC00022,RC00060,RC00069,RC00183,RC00557,RC02834	ko00000,ko00001,ko00002,ko01000,ko02048,ko03016	-	-	-	DUF2905,GCV_T,GCV_T_C
CMS1_k127_4550902_11	1201290.M902_1586	1.076e-32	131.0	COG0316@1|root,COG0316@2|Bacteria,1RH6T@1224|Proteobacteria,43ADA@68525|delta/epsilon subdivisions,2MUSB@213481|Bdellovibrionales,2X5SP@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	Iron-sulphur cluster biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Fe-S_biosyn
CMS1_k127_4550902_4	1303518.CCALI_01094	7.261e-120	390.0	COG5285@1|root,COG5285@2|Bacteria	2|Bacteria	Q	dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
CMS1_k127_4550902_3	1121124.JNIX01000013_gene1445	3.763e-127	444.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2TRFB@28211|Alphaproteobacteria,2KFVI@204458|Caulobacterales	204458|Caulobacterales	S	PFAM peptidase M16 domain protein	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
CMS1_k127_4550902_12	1123242.JH636434_gene3351	6.008e-29	136.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS1_k127_4550902_13	1144275.COCOR_07912	3.115e-19	104.0	COG4932@1|root,COG4932@2|Bacteria,1R5S8@1224|Proteobacteria	1224|Proteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS1_k127_4550902_2	889378.Spiaf_2832	3.334e-127	417.0	COG0379@1|root,COG0379@2|Bacteria,2JAE2@203691|Spirochaetes	203691|Spirochaetes	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
CMS1_k127_4550902_9	472759.Nhal_0692	2.666e-50	182.0	COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,1S3P1@1236|Gammaproteobacteria,1WW3I@135613|Chromatiales	135613|Chromatiales	C	A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters	-	-	-	ko:K04488,ko:K13819	-	-	-	-	ko00000	-	-	-	Fer2_BFD,NifU,NifU_N
CMS1_k127_4550902_1	671143.DAMO_2380	1.166e-172	551.0	COG0520@1|root,COG0520@2|Bacteria,2NNS0@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	sufS	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
CMS1_k127_4550902_7	861299.J421_2088	2.619e-102	347.0	COG0719@1|root,COG0719@2|Bacteria,1ZSTG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
CMS1_k127_4550902_5	945713.IALB_2894	7.712e-116	377.0	COG0396@1|root,COG0396@2|Bacteria	2|Bacteria	O	ATPase activity	sufC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	iECH74115_1262.ECH74115_2396,iECIAI1_1343.ECIAI1_1734,iECIAI39_1322.ECIAI39_1376,iECSP_1301.ECSP_2249,iECs_1301.ECs2389,iEcSMS35_1347.EcSMS35_1514,iG2583_1286.G2583_2077,iSFV_1184.SFV_1705,iSFxv_1172.SFxv_1919,iSSON_1240.SSON_1474,iS_1188.S1844,iZ_1308.Z2710	ABC_tran
CMS1_k127_4550902_0	234267.Acid_7699	1.656e-246	770.0	COG0719@1|root,COG0719@2|Bacteria,3Y2IX@57723|Acidobacteria	57723|Acidobacteria	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
CMS1_k127_4550902_8	660470.Theba_0067	1.128e-71	258.0	COG0407@1|root,COG0407@2|Bacteria	2|Bacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
CMS1_k127_4551493_1	1267535.KB906767_gene3249	8.052e-75	267.0	COG5434@1|root,COG5434@2|Bacteria,3Y2SR@57723|Acidobacteria,2JIUJ@204432|Acidobacteriia	204432|Acidobacteriia	M	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Pectate_lyase_3
CMS1_k127_4551493_0	1303518.CCALI_01741	6.46e-135	436.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS1_k127_4551493_2	530564.Psta_4263	2.594e-70	252.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	psrP1	-	-	-	-	-	-	-	-	-	-	-	CBM_6,CHU_C,GSDH,Malectin
CMS1_k127_4556655_0	1267535.KB906767_gene230	4.057e-108	355.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	AXE1,Peptidase_S9
CMS1_k127_4556655_1	227086.JGI_V11_33711	4.079e-67	235.0	2BBKE@1|root,2S0Y6@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_456074_2	760192.Halhy_1128	9.46e-39	161.0	COG3209@1|root,COG3209@2|Bacteria,4NFUE@976|Bacteroidetes,1INSI@117747|Sphingobacteriia	976|Bacteroidetes	M	COG3209 Rhs family protein	rhsA	-	-	-	-	-	-	-	-	-	-	-	RHS,RHS_repeat
CMS1_k127_456074_5	760192.Halhy_1128	1.175e-09	63.0	COG3209@1|root,COG3209@2|Bacteria,4NFUE@976|Bacteroidetes,1INSI@117747|Sphingobacteriia	976|Bacteroidetes	M	COG3209 Rhs family protein	rhsA	-	-	-	-	-	-	-	-	-	-	-	RHS,RHS_repeat
CMS1_k127_456074_4	760192.Halhy_1128	1.775e-24	117.0	COG3209@1|root,COG3209@2|Bacteria,4NFUE@976|Bacteroidetes,1INSI@117747|Sphingobacteriia	976|Bacteroidetes	M	COG3209 Rhs family protein	rhsA	-	-	-	-	-	-	-	-	-	-	-	RHS,RHS_repeat
CMS1_k127_456074_6	457429.ABJI02000051_gene2044	0.0003189	51.0	COG0457@1|root,COG0457@2|Bacteria,2GMGN@201174|Actinobacteria	201174|Actinobacteria	KLT	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
CMS1_k127_456074_1	1121939.L861_13660	8.823e-73	263.0	COG1520@1|root,COG1520@2|Bacteria,1NYGT@1224|Proteobacteria,1T1IK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotran_2,Arylsulfotrans
CMS1_k127_456074_0	382464.ABSI01000016_gene740	7.543e-121	418.0	COG2982@1|root,COG4932@1|root,COG2982@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K13735	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	AsmA_2,CHU_C,Cna_B,DUF11,Invasin_D3,PPC,Peptidase_M10_C,Reprolysin_4,SprB,VCBS
CMS1_k127_456074_3	548477.HMPREF0294_0332	7.674e-25	122.0	COG2885@1|root,COG3266@1|root,COG2885@2|Bacteria,COG3266@2|Bacteria,2I6XH@201174|Actinobacteria,22MTB@1653|Corynebacteriaceae	2|Bacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	Collagen,G5,TSP_3,YSIRK_signal
CMS1_k127_4561159_1	357809.Cphy_0388	7.884e-47	181.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_4561159_2	7460.GB44163-PA	9.528e-06	58.0	COG0457@1|root,KOG1124@2759|Eukaryota,38CY4@33154|Opisthokonta,3BDZ9@33208|Metazoa,3CW1H@33213|Bilateria,41VA9@6656|Arthropoda,3SKNK@50557|Insecta,46GGS@7399|Hymenoptera	33208|Metazoa	S	Transmembrane and TPR repeat-containing protein	TMTC2	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0008150,GO:0012505,GO:0016020,GO:0031984,GO:0042175,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0048878,GO:0050801,GO:0055065,GO:0055074,GO:0055080,GO:0065007,GO:0065008,GO:0072507,GO:0098771,GO:0098827	-	-	-	-	-	-	-	-	-	-	DUF1736,TPR_1,TPR_16,TPR_2,TPR_8
CMS1_k127_4561159_0	247639.MGP2080_02106	3.466e-152	506.0	COG2010@1|root,COG2010@2|Bacteria,1QX4J@1224|Proteobacteria	1224|Proteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Cu2_monoox_C,Cu2_monooxygen,Redoxin
CMS1_k127_4564142_5	243090.RB10999	4.094e-112	374.0	COG4409@1|root,COG4409@2|Bacteria,2J1WK@203682|Planctomycetes	203682|Planctomycetes	M	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2,Laminin_G_3
CMS1_k127_4564142_4	313603.FB2170_05575	2.225e-114	375.0	COG0656@1|root,COG0656@2|Bacteria,4NFTA@976|Bacteroidetes,1HXQP@117743|Flavobacteriia,2PGAM@252356|Maribacter	976|Bacteroidetes	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS1_k127_4564142_2	344747.PM8797T_13053	2.242e-118	392.0	COG2755@1|root,COG2755@2|Bacteria,2J28X@203682|Planctomycetes	203682|Planctomycetes	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4564142_3	1304888.ATWF01000001_gene1301	7.148e-115	377.0	COG0428@1|root,COG0428@2|Bacteria,2GFCI@200930|Deferribacteres	200930|Deferribacteres	P	ZIP Zinc transporter	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
CMS1_k127_4564142_1	886293.Sinac_0668	2.058e-147	479.0	COG0399@1|root,COG0399@2|Bacteria	2|Bacteria	E	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
CMS1_k127_4564142_8	1038860.AXAP01000033_gene4449	2.196e-05	47.0	COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria,2U24Y@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Integrase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve,rve_3
CMS1_k127_4564142_9	1121396.KB893120_gene3067	0.000838	46.0	COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria,42YNG@68525|delta/epsilon subdivisions,2WU6B@28221|Deltaproteobacteria,2MN61@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Integrase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4564142_6	1267535.KB906767_gene361	4.15e-95	328.0	COG0673@1|root,COG0673@2|Bacteria,3Y6Q3@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_4564142_7	1123242.JH636434_gene5272	1.055e-39	166.0	COG1621@1|root,COG1621@2|Bacteria,2IY26@203682|Planctomycetes	2|Bacteria	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Dockerin_1,HTH_18,RicinB_lectin_2
CMS1_k127_4564142_0	1288963.ADIS_1157	2.305e-290	911.0	COG3292@1|root,COG3292@2|Bacteria,4P1XS@976|Bacteroidetes,47U9C@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4565953_1	926569.ANT_18970	1.799e-91	303.0	COG0081@1|root,COG0081@2|Bacteria,2G6AW@200795|Chloroflexi	200795|Chloroflexi	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
CMS1_k127_4565953_2	926569.ANT_18980	2.639e-69	238.0	COG0080@1|root,COG0080@2|Bacteria,2G6FF@200795|Chloroflexi	200795|Chloroflexi	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
CMS1_k127_4565953_0	926569.ANT_18990	6.193e-98	323.0	COG0250@1|root,COG0250@2|Bacteria,2G6A3@200795|Chloroflexi	200795|Chloroflexi	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
CMS1_k127_4570721_3	287986.DV20_09855	7.983e-43	159.0	COG0326@1|root,COG0326@2|Bacteria,2GNPQ@201174|Actinobacteria,4DZ66@85010|Pseudonocardiales	201174|Actinobacteria	O	Molecular chaperone. Has ATPase activity	htpG	GO:0000302,GO:0000303,GO:0000305,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0010035,GO:0016020,GO:0030312,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044464,GO:0050896,GO:0051716,GO:0070887,GO:0071450,GO:0071451,GO:0071944,GO:1901700,GO:1901701	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
CMS1_k127_4570721_2	1499967.BAYZ01000195_gene3106	2.957e-123	412.0	COG1807@1|root,COG1807@2|Bacteria,2NPZC@2323|unclassified Bacteria	2|Bacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	MA20_19960	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS1_k127_4570721_5	1242864.D187_007073	3.871e-07	61.0	COG3385@1|root,COG3385@2|Bacteria,1RK5C@1224|Proteobacteria,43CJU@68525|delta/epsilon subdivisions,2X7U7@28221|Deltaproteobacteria,2Z16K@29|Myxococcales	28221|Deltaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
CMS1_k127_4570721_4	1242864.D187_007073	2.079e-10	64.0	COG3385@1|root,COG3385@2|Bacteria,1RK5C@1224|Proteobacteria,43CJU@68525|delta/epsilon subdivisions,2X7U7@28221|Deltaproteobacteria,2Z16K@29|Myxococcales	28221|Deltaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
CMS1_k127_4570721_1	1419583.V466_08800	6.562e-189	609.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,1RQ7D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	asparagine synthase, glutamine-hydrolyzing	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
CMS1_k127_4570721_0	1120968.AUBX01000010_gene1207	1.053e-197	633.0	COG3119@1|root,COG3119@2|Bacteria,4NF1X@976|Bacteroidetes,47KZP@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CMS1_k127_4570721_6	1403819.BATR01000102_gene3422	4.626e-05	46.0	COG0673@1|root,COG0673@2|Bacteria,46SJ7@74201|Verrucomicrobia	74201|Verrucomicrobia	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_4573676_4	1288963.ADIS_1775	2.457e-58	229.0	COG1621@1|root,COG1621@2|Bacteria,4P0AM@976|Bacteroidetes	976|Bacteroidetes	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4573676_0	234267.Acid_4558	0.0	1045.0	COG3391@1|root,COG3391@2|Bacteria,3Y2IM@57723|Acidobacteria	57723|Acidobacteria	S	Beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase,Phosphoesterase
CMS1_k127_4573676_6	459495.SPLC1_S360650	1.186e-09	68.0	COG2982@1|root,COG2982@2|Bacteria,1GA4Q@1117|Cyanobacteria,1HG5E@1150|Oscillatoriales	1117|Cyanobacteria	M	AsmA family	-	-	-	-	-	-	-	-	-	-	-	-	AsmA
CMS1_k127_4573676_3	1120972.AUMH01000001_gene1051	3.179e-67	236.0	COG2077@1|root,COG2077@2|Bacteria,1V474@1239|Firmicutes,4HFMW@91061|Bacilli,279T1@186823|Alicyclobacillaceae	91061|Bacilli	O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides	tpx	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA,Redoxin
CMS1_k127_4573676_7	926550.CLDAP_01400	2.545e-05	50.0	COG2345@1|root,COG2345@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	ATC_hydrolase,SWIM
CMS1_k127_4573676_1	243090.RB9026	2.031e-148	481.0	COG0673@1|root,COG0673@2|Bacteria,2IX39@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_4573676_2	1304876.AZVC01000008_gene1905	1.108e-119	404.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria	201174|Actinobacteria	P	Pfam Sulfatase	atsG	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS1_k127_4573676_5	880073.Calab_2819	1.435e-42	180.0	COG3345@1|root,COG3345@2|Bacteria,2NRYT@2323|unclassified Bacteria	2|Bacteria	G	Melibiase	rafA	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	F5_F8_type_C,FIVAR,Glyco_hydro_36C,Glyco_hydro_36N,Melibiase
CMS1_k127_4577583_2	1279009.ADICEAN_00691	5.811e-22	111.0	COG3210@1|root,COG3291@1|root,COG4733@1|root,COG3210@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria,4NDZC@976|Bacteroidetes,47SFQ@768503|Cytophagia	976|Bacteroidetes	O	HYR domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,PKD,SASA,SprB
CMS1_k127_4577583_1	1449063.JMLS01000011_gene312	1.844e-101	341.0	COG3669@1|root,COG3669@2|Bacteria	2|Bacteria	G	Alpha-L-fucosidase	-	-	-	-	-	-	-	-	-	-	-	-	Alpha_L_fucos,Big_2,CBM_X2,CHB_HEX_C_1,F5_F8_type_C,FIVAR,Glyco_hyd_65N_2,Melibiase_2
CMS1_k127_4577583_0	1160707.AJIK01000002_gene459	6.383e-176	558.0	COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,4HAG1@91061|Bacilli,26DYZ@186818|Planococcaceae	91061|Bacilli	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
CMS1_k127_4580123_1	398767.Glov_1382	7.448e-28	117.0	COG1996@1|root,COG1996@2|Bacteria,1QV33@1224|Proteobacteria,43CNA@68525|delta/epsilon subdivisions,2X7VK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4580123_0	1116472.MGMO_37c00330	2.209e-149	480.0	COG4260@1|root,COG4260@2|Bacteria,1MXTD@1224|Proteobacteria,1S1VG@1236|Gammaproteobacteria,1XG0E@135618|Methylococcales	135618|Methylococcales	S	Domain of unknown function (DUF4339)	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DUF4339
CMS1_k127_4580123_2	573370.DMR_08620	2.478e-07	62.0	COG1075@1|root,COG1075@2|Bacteria,1NYAK@1224|Proteobacteria,42Q3C@68525|delta/epsilon subdivisions,2WMAK@28221|Deltaproteobacteria,2MA00@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
CMS1_k127_4580880_16	1183438.GKIL_3198	6.072e-74	259.0	COG1879@1|root,COG1879@2|Bacteria,1G06J@1117|Cyanobacteria	1117|Cyanobacteria	G	PFAM periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
CMS1_k127_4580880_2	1303518.CCALI_01101	1.355e-192	614.0	COG1129@1|root,COG1129@2|Bacteria	2|Bacteria	G	ABC transporter	rbsA	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
CMS1_k127_4580880_18	1232666.JANE01000081_gene276	1.538e-60	224.0	COG1172@1|root,COG1172@2|Bacteria,1TP72@1239|Firmicutes,4H9Y3@91061|Bacilli,4GY3M@90964|Staphylococcaceae	91061|Bacilli	G	Belongs to the binding-protein-dependent transport system permease family	rbsC	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015749,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0034219,GO:0044425,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
CMS1_k127_4580880_33	1123400.KB904766_gene2962	6.208e-08	62.0	290RU@1|root,2ZNDZ@2|Bacteria,1P98B@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4580880_32	1242864.D187_001827	7.798e-13	83.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Cadherin_3,DUF285,TSP_3
CMS1_k127_4580880_28	575540.Isop_2194	2.048e-20	107.0	COG0388@1|root,COG0388@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	-	-	3.4.13.22	ko:K08641,ko:K11206	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	CN_hydrolase,Peptidase_M15
CMS1_k127_4580880_30	926564.KI911742_gene3303	4.334e-19	103.0	COG1874@1|root,COG1874@2|Bacteria,2GMDT@201174|Actinobacteria,4F42Q@85017|Promicromonosporaceae	201174|Actinobacteria	G	Beta-galactosidase C-terminal domain	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
CMS1_k127_4580880_34	339860.Msp_0261	4.591e-07	63.0	COG5427@1|root,arCOG00563@2157|Archaea,2Y3TV@28890|Euryarchaeota,23PKA@183925|Methanobacteria	183925|Methanobacteria	S	membrane protein, required for N-linked glycosylation	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS1_k127_4580880_10	452637.Oter_1003	7.655e-88	304.0	COG4299@1|root,COG4299@2|Bacteria,46S60@74201|Verrucomicrobia	74201|Verrucomicrobia	S	COGs COG4299 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624,DUF5009
CMS1_k127_4580880_23	1329516.JPST01000006_gene1669	1.199e-49	194.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,4HDN8@91061|Bacilli,27C0D@186824|Thermoactinomycetaceae	91061|Bacilli	M	DegT/DnrJ/EryC1/StrS aminotransferase family	pseC	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
CMS1_k127_4580880_13	264732.Moth_0701	2.446e-79	276.0	COG1172@1|root,COG1172@2|Bacteria,1TP72@1239|Firmicutes,249FA@186801|Clostridia,42G0Z@68295|Thermoanaerobacterales	186801|Clostridia	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
CMS1_k127_4580880_17	1304888.ATWF01000001_gene2118	1.039e-66	256.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,2GF2A@200930|Deferribacteres	200930|Deferribacteres	M	Lysin motif	-	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
CMS1_k127_4580880_15	751945.Theos_0263	5.73e-75	271.0	COG2805@1|root,COG2805@2|Bacteria,1WI5S@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	NU	Tfp pilus assembly protein pilus retraction ATPase PilT	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
CMS1_k127_4580880_5	1121438.JNJA01000006_gene167	1.159e-139	460.0	COG4773@1|root,COG4773@2|Bacteria,1QCTH@1224|Proteobacteria,42PPC@68525|delta/epsilon subdivisions,2WIS8@28221|Deltaproteobacteria,2MAAG@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Receptor	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4580880_12	1125863.JAFN01000001_gene70	9.032e-87	299.0	COG2834@1|root,COG2834@2|Bacteria,1MXW0@1224|Proteobacteria,42MX6@68525|delta/epsilon subdivisions,2WMMJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
CMS1_k127_4580880_0	349521.HCH_05429	2.444e-292	926.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RPIP@1236|Gammaproteobacteria,1XISF@135619|Oceanospirillales	135619|Oceanospirillales	M	Sterol-sensing domain of SREBP cleavage-activation	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
CMS1_k127_4580880_31	207559.Dde_4012	7.023e-19	90.0	COG0607@1|root,32YCZ@2|Bacteria,1N6NN@1224|Proteobacteria,42VWR@68525|delta/epsilon subdivisions,2WS4U@28221|Deltaproteobacteria,2MDYF@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
CMS1_k127_4580880_29	1417296.U879_12375	2.666e-19	90.0	COG0438@1|root,COG0438@2|Bacteria,1MVKK@1224|Proteobacteria,2TUFG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
CMS1_k127_4580880_19	742735.HMPREF9467_02955	1.5e-56	213.0	COG0438@1|root,COG0438@2|Bacteria,1UASH@1239|Firmicutes,248VW@186801|Clostridia,221DV@1506553|Lachnoclostridium	186801|Clostridia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS1_k127_4580880_1	926569.ANT_00890	1.448e-287	897.0	28I0T@1|root,2Z85H@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4914)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4914
CMS1_k127_4580880_26	1128427.KB904821_gene1406	1.774e-32	138.0	COG0457@1|root,COG0457@2|Bacteria,1G36K@1117|Cyanobacteria,1H9PH@1150|Oscillatoriales	1117|Cyanobacteria	O	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,TPR_1,TPR_11,TPR_2,TPR_4,TPR_8,Trypsin_2
CMS1_k127_4580880_14	1254432.SCE1572_38245	2.269e-77	291.0	COG1948@1|root,COG5276@1|root,COG4880@2|Bacteria,COG5276@2|Bacteria,1P2CI@1224|Proteobacteria	1224|Proteobacteria	L	Beta propeller domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta_propel
CMS1_k127_4580880_22	1408473.JHXO01000004_gene191	4.594e-51	184.0	COG2606@1|root,COG2606@2|Bacteria,4P3TW@976|Bacteroidetes,2FXVH@200643|Bacteroidia	976|Bacteroidetes	S	Aminoacyl-tRNA editing domain	-	-	-	ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
CMS1_k127_4580880_36	1121931.AUHG01000011_gene2208	9.117e-06	57.0	COG0793@1|root,COG0793@2|Bacteria,4NEK8@976|Bacteroidetes,1HYIK@117743|Flavobacteriia	976|Bacteroidetes	M	peptidase S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
CMS1_k127_4580880_6	204669.Acid345_0704	3.749e-110	369.0	COG2805@1|root,COG2805@2|Bacteria,3Y316@57723|Acidobacteria,2JIT4@204432|Acidobacteriia	204432|Acidobacteriia	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
CMS1_k127_4580880_8	765912.Thimo_0557	1.834e-94	320.0	COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,1RN8M@1236|Gammaproteobacteria,1WWRX@135613|Chromatiales	135613|Chromatiales	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
CMS1_k127_4580880_24	429009.Adeg_0864	2.772e-39	165.0	COG0860@1|root,COG2861@1|root,COG0860@2|Bacteria,COG2861@2|Bacteria,1V413@1239|Firmicutes,24HY1@186801|Clostridia,42GR2@68295|Thermoanaerobacterales	186801|Clostridia	M	Divergent polysaccharide deacetylase	-	-	-	ko:K09798	-	-	-	-	ko00000	-	-	-	Amidase_3,Polysacc_deac_2
CMS1_k127_4580880_11	1297742.A176_05295	1.85e-87	299.0	COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,42P58@68525|delta/epsilon subdivisions,2WKYK@28221|Deltaproteobacteria,2YY1K@29|Myxococcales	28221|Deltaproteobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_0547	Asp_Glu_race
CMS1_k127_4580880_37	697281.Mahau_0907	0.0005731	50.0	COG5401@1|root,COG5401@2|Bacteria,1U1ZK@1239|Firmicutes,24AQU@186801|Clostridia,42F70@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM Spore germination protein-like Gmad2, bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Germane,Gmad2
CMS1_k127_4580880_27	1229172.JQFA01000004_gene1486	9.719e-27	122.0	COG0860@1|root,COG0860@2|Bacteria,1G008@1117|Cyanobacteria,1H876@1150|Oscillatoriales	1117|Cyanobacteria	M	N-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
CMS1_k127_4580880_21	1210884.HG799462_gene7872	1.082e-53	198.0	COG0095@1|root,COG0095@2|Bacteria,2J0D8@203682|Planctomycetes	203682|Planctomycetes	H	PFAM Biotin lipoate A B protein ligase	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
CMS1_k127_4580880_3	316067.Geob_1260	3.057e-180	578.0	COG1003@1|root,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,42MR9@68525|delta/epsilon subdivisions,2WIP3@28221|Deltaproteobacteria,43TFR@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	PFAM glycine cleavage system P-protein	gcvP	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5,GDC-P
CMS1_k127_4580880_4	1121440.AUMA01000010_gene488	1.591e-142	465.0	COG0403@1|root,COG0403@2|Bacteria,1MVC1@1224|Proteobacteria,42MQ1@68525|delta/epsilon subdivisions,2WJII@28221|Deltaproteobacteria,2M9HZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
CMS1_k127_4580880_25	2342.SOPEG_3902	2.309e-37	149.0	COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,1S656@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	GO:0001505,GO:0003674,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0017144,GO:0019464,GO:0019752,GO:0031405,GO:0031406,GO:0033293,GO:0036094,GO:0042133,GO:0042135,GO:0042737,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901681	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	iE2348C_1286.E2348C_3156,iPC815.YPO0906	GCV_H
CMS1_k127_4580880_9	269799.Gmet_3155	1.008e-88	306.0	COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,42QM6@68525|delta/epsilon subdivisions,2WJ8G@28221|Deltaproteobacteria,43TN6@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	PFAM glycine cleavage T protein (aminomethyl transferase)	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
CMS1_k127_4580880_7	261292.Nit79A3_1329	7.467e-106	357.0	COG1073@1|root,COG1073@2|Bacteria,1QY08@1224|Proteobacteria,2VMYE@28216|Betaproteobacteria	28216|Betaproteobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4580880_35	648757.Rvan_0746	6.32e-07	62.0	COG1752@1|root,COG1752@2|Bacteria,1PI8V@1224|Proteobacteria,2VD78@28211|Alphaproteobacteria,3N96B@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
CMS1_k127_4580880_20	1174528.JH992898_gene5340	8.625e-56	208.0	COG4188@1|root,COG4188@2|Bacteria,1GD7B@1117|Cyanobacteria	1117|Cyanobacteria	S	Platelet-activating factor acetylhydrolase, isoform II	-	-	-	-	-	-	-	-	-	-	-	-	PAF-AH_p_II
CMS1_k127_4589433_0	926550.CLDAP_31570	8.633e-110	363.0	COG0673@1|root,COG0673@2|Bacteria,2G6KB@200795|Chloroflexi	200795|Chloroflexi	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_4589433_9	1288963.ADIS_4867	9.487e-05	54.0	COG0236@1|root,COG0236@2|Bacteria,4PNV3@976|Bacteroidetes	976|Bacteroidetes	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4589433_2	1123508.JH636450_gene7227	2.354e-49	183.0	2DBSY@1|root,32TY1@2|Bacteria,2J0DA@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4589433_4	1047013.AQSP01000106_gene1780	1.455e-34	138.0	COG3296@1|root,COG3296@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4870)	-	-	-	ko:K09940	-	-	-	-	ko00000	-	-	-	DUF4870
CMS1_k127_4589433_6	1123508.JH636443_gene4841	8.112e-30	123.0	COG3324@1|root,COG3324@2|Bacteria,2J4IN@203682|Planctomycetes	203682|Planctomycetes	S	Glyoxalase-like domain	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
CMS1_k127_4589433_5	1005048.CFU_3298	1.183e-33	138.0	COG5580@1|root,COG5580@2|Bacteria,1NMBI@1224|Proteobacteria,2W5GZ@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
CMS1_k127_4589433_3	720554.Clocl_0784	1.233e-37	151.0	COG0145@1|root,COG0145@2|Bacteria,1V3GN@1239|Firmicutes,25DNJ@186801|Clostridia,3WPEF@541000|Ruminococcaceae	186801|Clostridia	EQ	Protein of unknown function (DUF1638)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1638
CMS1_k127_4589433_1	1123242.JH636434_gene3217	5.195e-51	185.0	2CDSB@1|root,347TN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4589433_7	880071.Fleli_1611	3.082e-28	128.0	COG5316@1|root,COG5316@2|Bacteria,4NNBK@976|Bacteroidetes,47TJH@768503|Cytophagia	976|Bacteroidetes	S	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4591372_1	1382304.JNIL01000001_gene3015	5.686e-82	278.0	COG2896@1|root,COG2896@2|Bacteria,1TP89@1239|Firmicutes,4HAKQ@91061|Bacilli,279ER@186823|Alicyclobacillaceae	91061|Bacilli	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
CMS1_k127_4591372_0	118173.KB235914_gene505	6.106e-87	298.0	COG2041@1|root,COG2041@2|Bacteria,1G169@1117|Cyanobacteria,1H9HS@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Oxidoreductase molybdopterin binding domain	-	-	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_molyb
CMS1_k127_4591372_2	391612.CY0110_03089	3.888e-58	207.0	28NY3@1|root,2ZBVC@2|Bacteria,1G5MR@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_459652_6	1007103.AFHW01000035_gene1925	0.0003809	48.0	COG2318@1|root,COG2318@2|Bacteria,1V51W@1239|Firmicutes,4HIYI@91061|Bacilli,26WFX@186822|Paenibacillaceae	91061|Bacilli	S	Damage-inducible protein DinB	dinB	-	-	-	-	-	-	-	-	-	-	-	DinB
CMS1_k127_459652_5	1282362.AEAC466_13000	9.17e-05	51.0	COG1051@1|root,COG1051@2|Bacteria,1N0YW@1224|Proteobacteria,2UC2E@28211|Alphaproteobacteria,2KGP2@204458|Caulobacterales	204458|Caulobacterales	F	Belongs to the Nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS1_k127_459652_1	926560.KE387027_gene519	7.269e-82	279.0	COG2045@1|root,COG2045@2|Bacteria,1WMIA@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	2-phosphosulpholactate phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	2-ph_phosp
CMS1_k127_459652_0	344747.PM8797T_06240	2.49e-149	477.0	COG1090@1|root,COG1090@2|Bacteria,2IYWK@203682|Planctomycetes	203682|Planctomycetes	S	nucleoside-diphosphate sugar epimerase	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
CMS1_k127_459652_2	316067.Geob_0328	4.149e-57	204.0	COG0346@1|root,COG0346@2|Bacteria,1N116@1224|Proteobacteria,42SZW@68525|delta/epsilon subdivisions,2WPFI@28221|Deltaproteobacteria,43VJR@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Glyoxalase-like domain	-	-	-	ko:K07032	-	-	-	-	ko00000	-	-	-	Glyoxalase
CMS1_k127_459652_4	1392838.AWNM01000075_gene424	8.068e-17	89.0	COG0655@1|root,COG0655@2|Bacteria,1RCJ8@1224|Proteobacteria,2WAYB@28216|Betaproteobacteria,3T754@506|Alcaligenaceae	28216|Betaproteobacteria	S	Flavodoxin-like fold	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_2
CMS1_k127_4613153_4	1210908.HSB1_11320	4.494e-33	139.0	arCOG13016@1|root,arCOG13016@2157|Archaea,2XXG4@28890|Euryarchaeota,23VQE@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4613153_3	296591.Bpro_3359	1.337e-34	137.0	COG0527@1|root,COG0527@2|Bacteria,1REUY@1224|Proteobacteria,2VS69@28216|Betaproteobacteria	28216|Betaproteobacteria	E	ACT domain	-	-	-	-	-	-	-	-	-	-	-	-	ACT,ACT_6
CMS1_k127_4613153_1	1303518.CCALI_02380	3.314e-88	300.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red
CMS1_k127_4613153_5	521045.Kole_1248	2.508e-10	74.0	COG1305@1|root,COG1305@2|Bacteria	2|Bacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
CMS1_k127_4613153_0	1282360.ABAC460_06910	5.897e-100	346.0	COG1331@1|root,COG1331@2|Bacteria,1R570@1224|Proteobacteria,2TUBQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Pectic acid lyase	-	-	-	-	-	-	-	-	-	-	-	-	Pec_lyase
CMS1_k127_4613153_2	391735.Veis_1396	5.715e-80	280.0	COG0673@1|root,COG0673@2|Bacteria,1MUP0@1224|Proteobacteria,2VMEP@28216|Betaproteobacteria,4AAKK@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM oxidoreductase domain protein	bplA	-	1.1.1.335	ko:K13020	ko00520,map00520	-	R10140	RC00182	ko00000,ko00001,ko01000,ko01005	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_4613153_6	471875.RUMLAC_01520	8.325e-05	57.0	COG3534@1|root,COG4733@1|root,COG3534@2|Bacteria,COG4733@2|Bacteria,1TR7B@1239|Firmicutes,248ZA@186801|Clostridia,3WGAE@541000|Ruminococcaceae	186801|Clostridia	G	Alpha-L-arabinofuranosidase	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
CMS1_k127_4633719_9	1227360.C176_01205	0.0004635	51.0	COG1277@1|root,COG1277@2|Bacteria,1TT9E@1239|Firmicutes,4HE5W@91061|Bacilli,26D1G@186818|Planococcaceae	91061|Bacilli	S	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_4
CMS1_k127_4633719_5	765420.OSCT_1892	3.473e-56	207.0	COG1131@1|root,COG1131@2|Bacteria,2G6B8@200795|Chloroflexi,375EE@32061|Chloroflexia	32061|Chloroflexia	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_4633719_3	696281.Desru_3272	2.621e-120	406.0	COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,247NU@186801|Clostridia,25ZYA@186807|Peptococcaceae	186801|Clostridia	L	TIGRFAM single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1,Helicase_C
CMS1_k127_4633719_7	439292.Bsel_2148	5.776e-51	189.0	COG0283@1|root,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,4HFZE@91061|Bacilli,26NTN@186821|Sporolactobacillaceae	91061|Bacilli	F	Cytidylate kinase-like family	cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
CMS1_k127_4633719_2	886293.Sinac_5114	9.448e-125	408.0	COG0182@1|root,COG0182@2|Bacteria,2IWRJ@203682|Planctomycetes	203682|Planctomycetes	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
CMS1_k127_4633719_4	391625.PPSIR1_08496	8.148e-88	300.0	COG2234@1|root,COG2234@2|Bacteria,1PY1F@1224|Proteobacteria,4350U@68525|delta/epsilon subdivisions,2WZBN@28221|Deltaproteobacteria,2Z1SK@29|Myxococcales	28221|Deltaproteobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
CMS1_k127_4633719_0	163908.KB235896_gene4635	6.268e-238	746.0	COG0318@1|root,COG0318@2|Bacteria,1G2H0@1117|Cyanobacteria,1HIDR@1161|Nostocales	1117|Cyanobacteria	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	6.2.1.3	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
CMS1_k127_4633719_1	1026882.MAMP_02634	2.293e-130	444.0	COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria,1RNUB@1236|Gammaproteobacteria,460Y9@72273|Thiotrichales	72273|Thiotrichales	M	Mechanosensitive ion channel	-	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
CMS1_k127_4633719_8	1125863.JAFN01000001_gene2910	2.016e-44	175.0	COG1011@1|root,COG1011@2|Bacteria,1NIPN@1224|Proteobacteria	1224|Proteobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
CMS1_k127_4633719_6	483219.LILAB_27880	5.613e-53	194.0	COG1716@1|root,COG2114@1|root,COG2203@1|root,COG1716@2|Bacteria,COG2114@2|Bacteria,COG2203@2|Bacteria,1RAHZ@1224|Proteobacteria,42UGY@68525|delta/epsilon subdivisions,2WQPI@28221|Deltaproteobacteria,2YUG9@29|Myxococcales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,GAF,GAF_2,Guanylate_cyc
CMS1_k127_4655248_1	589865.DaAHT2_1873	4.564e-60	218.0	COG1235@1|root,COG1235@2|Bacteria,1R5N4@1224|Proteobacteria,42NE6@68525|delta/epsilon subdivisions,2WJ92@28221|Deltaproteobacteria,2MJ1B@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Lactamase_B_2
CMS1_k127_4655248_0	644282.Deba_1961	7.045e-99	340.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,42M3C@68525|delta/epsilon subdivisions,2WJ21@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
CMS1_k127_4657516_1	679199.HMPREF9332_01395	2.219e-144	490.0	COG3525@1|root,COG3525@2|Bacteria,4NEQN@976|Bacteroidetes,2FMUE@200643|Bacteroidia	976|Bacteroidetes	G	F5 8 type C domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4838,F5_F8_type_C,Glyco_hydro_67N
CMS1_k127_4657516_6	661478.OP10G_2205	8.598e-12	79.0	COG3934@1|root,COG3934@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.4	ko:K01179,ko:K13276	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	GH5,GH9	-	Cellulase,F5_F8_type_C,FIVAR
CMS1_k127_4657516_2	1499967.BAYZ01000104_gene3654	9.193e-75	259.0	COG1723@1|root,COG1723@2|Bacteria	2|Bacteria	S	PFAM Uncharacterised ACR, YagE family COG1723	yagE	-	-	-	-	-	-	-	-	-	-	-	DUF155
CMS1_k127_4657516_0	1110502.TMO_0632	3.009e-272	854.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2TS8E@28211|Alphaproteobacteria,2JPNR@204441|Rhodospirillales	204441|Rhodospirillales	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
CMS1_k127_4657516_5	313612.L8106_20498	4.603e-30	124.0	COG1842@1|root,COG1842@2|Bacteria,1G2PP@1117|Cyanobacteria,1H9Y4@1150|Oscillatoriales	1117|Cyanobacteria	KT	Phage shock protein A (IM30), suppresses sigma54-dependent transcription	-	-	-	-	-	-	-	-	-	-	-	-	LRAT,PspA_IM30
CMS1_k127_4657516_3	204669.Acid345_0349	2.252e-71	251.0	COG1075@1|root,COG1075@2|Bacteria,3Y77G@57723|Acidobacteria	57723|Acidobacteria	S	PGAP1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4657516_4	234267.Acid_1785	1.31e-50	188.0	COG1020@1|root,COG1020@2|Bacteria,3Y61Y@57723|Acidobacteria	57723|Acidobacteria	H	Protein of unknown function (DUF1298)	-	-	2.3.1.20	ko:K00635	ko00561,ko01100,map00561,map01100	M00089	R02251	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1298,WES_acyltransf
CMS1_k127_4664751_0	880074.BARVI_08535	3.277e-46	169.0	COG2081@1|root,COG2081@2|Bacteria,4PMNY@976|Bacteroidetes,2FQ67@200643|Bacteroidia,22W1E@171551|Porphyromonadaceae	976|Bacteroidetes	S	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
CMS1_k127_4664751_1	46681.XP_001733779.1	2.068e-07	63.0	2CSYB@1|root,2RDTF@2759|Eukaryota,3XCPR@554915|Amoebozoa	554915|Amoebozoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4667925_0	278963.ATWD01000001_gene3347	6.647e-114	383.0	COG5434@1|root,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBM-like,F5_F8_type_C,Pectate_lyase_3
CMS1_k127_4679462_2	1479235.KK366039_gene329	8.068e-05	48.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,1RMW6@1236|Gammaproteobacteria,1XHZN@135619|Oceanospirillales	135619|Oceanospirillales	S	DNA internalization-related competence protein ComEC Rec2	rec2	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
CMS1_k127_4679462_0	485913.Krac_11000	3.138e-91	313.0	COG1609@1|root,COG1609@2|Bacteria	2|Bacteria	K	purine nucleotide biosynthetic process	-	-	5.3.1.12	ko:K01812,ko:K02529,ko:K16210	ko00040,ko01100,map00040,map01100	M00061,M00631	R01482,R01983	RC00376	ko00000,ko00001,ko00002,ko01000,ko02000,ko03000	2.A.2.5	-	-	DDE_Tnp_ISAZ013,Peripla_BP_3
CMS1_k127_4679462_1	864069.MicloDRAFT_00004300	5.511e-09	66.0	COG3415@1|root,COG3415@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISAZ013,DUF3105,HTH_23,HTH_Tnp_4,rve
CMS1_k127_46850_1	314230.DSM3645_27186	3.483e-32	126.0	COG3622@1|root,COG3622@2|Bacteria,2IY93@203682|Planctomycetes	203682|Planctomycetes	G	Belongs to the hyi family	-	-	5.3.1.22	ko:K01816	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
CMS1_k127_46850_0	1434325.AZQN01000015_gene1376	1.767e-213	667.0	COG1482@1|root,COG1482@2|Bacteria,4NGGP@976|Bacteroidetes,47NZ6@768503|Cytophagia	976|Bacteroidetes	G	cell wall glycoprotein biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4686996_0	1476583.DEIPH_ctg066orf0013	2.823e-15	90.0	COG2340@1|root,COG5492@1|root,COG2340@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	ligA1	-	-	-	-	-	-	-	-	-	-	-	Big_2,CAP
CMS1_k127_4686996_1	357808.RoseRS_2323	8.054e-06	52.0	COG3209@1|root,COG3209@2|Bacteria,2G6KZ@200795|Chloroflexi,376AQ@32061|Chloroflexia	32061|Chloroflexia	M	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat
CMS1_k127_4698586_0	1123242.JH636434_gene3495	4.654e-127	442.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
CMS1_k127_4698586_1	44056.XP_009035520.1	2.893e-86	303.0	2E3BA@1|root,2SAF2@2759|Eukaryota	2759|Eukaryota	S	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP_2
CMS1_k127_4708843_3	234267.Acid_0683	1.545e-31	130.0	COG0673@1|root,COG0673@2|Bacteria,3Y6VS@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_4708843_4	1122919.KB905588_gene4044	4.364e-14	83.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
CMS1_k127_4708843_0	595460.RRSWK_04460	2.27e-112	369.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
CMS1_k127_4708843_1	1178825.ALIH01000014_gene1970	6.518e-58	220.0	COG0673@1|root,COG0673@2|Bacteria,4NFFJ@976|Bacteroidetes,1HXQ4@117743|Flavobacteriia	976|Bacteroidetes	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_4708843_2	314230.DSM3645_05889	4.937e-55	208.0	COG1477@1|root,COG1477@2|Bacteria,2IYYX@203682|Planctomycetes	203682|Planctomycetes	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
CMS1_k127_4708843_5	1123257.AUFV01000015_gene3589	4.646e-14	80.0	COG2353@1|root,COG2353@2|Bacteria,1N3P9@1224|Proteobacteria,1SDBE@1236|Gammaproteobacteria,1XAHR@135614|Xanthomonadales	135614|Xanthomonadales	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
CMS1_k127_4723852_0	485916.Dtox_0809	6.502e-275	874.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,2605R@186807|Peptococcaceae	186801|Clostridia	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
CMS1_k127_4723852_6	929713.NIASO_07085	3.308e-47	173.0	COG3011@1|root,COG3011@2|Bacteria,4NQ93@976|Bacteroidetes,1ITBQ@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function, DUF393	yuxK	-	-	-	-	-	-	-	-	-	-	-	DUF393
CMS1_k127_4723852_2	1341151.ASZU01000009_gene922	5.295e-132	435.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,4HDN8@91061|Bacilli,27C0D@186824|Thermoactinomycetaceae	91061|Bacilli	M	DegT/DnrJ/EryC1/StrS aminotransferase family	pseC	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
CMS1_k127_4723852_8	1321815.HMPREF9193_01423	0.0004452	51.0	2EI2Q@1|root,33BU4@2|Bacteria,2J65X@203691|Spirochaetes	203691|Spirochaetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4723852_3	497964.CfE428DRAFT_4945	1.383e-129	430.0	COG1541@1|root,COG1541@2|Bacteria,46SVW@74201|Verrucomicrobia	74201|Verrucomicrobia	H	AMP-binding enzyme C-terminal domain	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
CMS1_k127_4723852_7	573370.DMR_29190	2.89e-06	57.0	COG3161@1|root,COG3161@2|Bacteria,1Q8QT@1224|Proteobacteria,436TZ@68525|delta/epsilon subdivisions,2X1HP@28221|Deltaproteobacteria,2MF2Z@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	chorismate lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4723852_1	880073.Calab_2708	1.964e-147	482.0	COG1236@1|root,COG1236@2|Bacteria,2NNVC@2323|unclassified Bacteria	2|Bacteria	J	Beta-Casp domain	-	-	-	ko:K07576,ko:K07577	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_2,Lactamase_B_6,RMMBL
CMS1_k127_4723852_4	525904.Tter_1666	6.52e-117	396.0	COG0497@1|root,COG0497@2|Bacteria,2NNUS@2323|unclassified Bacteria	2|Bacteria	L	May be involved in recombinational repair of damaged DNA	recN	GO:0000724,GO:0000725,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009295,GO:0009314,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0030312,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071944,GO:0090304,GO:1901360	-	ko:K03631,ko:K13582	ko04112,map04112	-	-	-	ko00000,ko00001,ko03400	-	-	-	AAA_23,SMC_N
CMS1_k127_4723852_5	589865.DaAHT2_0442	2.908e-75	259.0	COG1189@1|root,COG1189@2|Bacteria,1MWP5@1224|Proteobacteria,42R2J@68525|delta/epsilon subdivisions,2WIJ6@28221|Deltaproteobacteria,2MIMF@213118|Desulfobacterales	28221|Deltaproteobacteria	J	PFAM ribosomal RNA methyltransferase RrmJ FtsJ	tlyA	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
CMS1_k127_473593_0	452637.Oter_1491	1.687e-07	64.0	COG3014@1|root,COG3014@2|Bacteria	2|Bacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS1_k127_4760666_5	240016.ABIZ01000001_gene2053	0.0001746	44.0	COG0492@1|root,COG0492@2|Bacteria	2|Bacteria	C	ferredoxin-NADP+ reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
CMS1_k127_4760666_3	1342301.JASD01000008_gene1025	5.18e-46	182.0	COG0738@1|root,COG0738@2|Bacteria,1QVNU@1224|Proteobacteria,2UMIH@28211|Alphaproteobacteria,3ZVC6@60136|Sulfitobacter	28211|Alphaproteobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_4760666_4	1163408.UU9_06094	3.18e-25	109.0	COG1937@1|root,COG1937@2|Bacteria,1N6ZN@1224|Proteobacteria,1S6I2@1236|Gammaproteobacteria,1X7IP@135614|Xanthomonadales	135614|Xanthomonadales	S	Metal-sensitive transcriptional repressor	frmR	-	-	-	-	-	-	-	-	-	-	-	Trns_repr_metal
CMS1_k127_4760666_1	530564.Psta_3159	3.246e-89	302.0	COG2513@1|root,COG2513@2|Bacteria,2IXH7@203682|Planctomycetes	203682|Planctomycetes	G	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate	prpB	-	4.1.3.30	ko:K03417	ko00640,map00640	-	R00409	RC00286,RC00287	ko00000,ko00001,ko01000	-	-	-	PEP_mutase
CMS1_k127_4760666_0	518766.Rmar_0100	1.357e-110	368.0	COG0372@1|root,COG0372@2|Bacteria,4NFXK@976|Bacteroidetes,1FIQ8@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Belongs to the citrate synthase family	prpC	-	2.3.3.1,2.3.3.5	ko:K01647,ko:K01659	ko00020,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351,R00931	RC00004,RC00067,RC00406,RC02827	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
CMS1_k127_4760666_2	575540.Isop_3370	2.702e-86	293.0	COG3386@1|root,COG3386@2|Bacteria,2J2MK@203682|Planctomycetes	203682|Planctomycetes	G	BNR repeat-containing family member	-	-	-	-	-	-	-	-	-	-	-	-	BNR_4
CMS1_k127_4766108_0	1047013.AQSP01000106_gene1773	2.561e-52	210.0	COG3119@1|root,COG3119@2|Bacteria,2NR0Q@2323|unclassified Bacteria	2|Bacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,DUF4976,Sulfatase
CMS1_k127_477628_0	1347369.CCAD010000008_gene2338	7.76e-84	286.0	COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,4H9QA@91061|Bacilli,1ZBQ0@1386|Bacillus	91061|Bacilli	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
CMS1_k127_477628_2	509191.AEDB02000048_gene4645	5.18e-36	146.0	COG0340@1|root,COG0340@2|Bacteria,1TQCU@1239|Firmicutes,248CK@186801|Clostridia,3WHDB@541000|Ruminococcaceae	186801|Clostridia	HK	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
CMS1_k127_477628_1	767817.Desgi_0291	5.496e-77	266.0	COG0157@1|root,COG0157@2|Bacteria,1TPQC@1239|Firmicutes,248P2@186801|Clostridia,26046@186807|Peptococcaceae	186801|Clostridia	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12010	QRPTase_C,QRPTase_N
CMS1_k127_477628_3	1121949.AQXT01000002_gene1144	1.675e-20	94.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,2TSTH@28211|Alphaproteobacteria,43WB8@69657|Hyphomonadaceae	28211|Alphaproteobacteria	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
CMS1_k127_4779494_0	1120950.KB892765_gene5704	5.811e-140	458.0	COG3119@1|root,COG3119@2|Bacteria,2IK10@201174|Actinobacteria	201174|Actinobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS1_k127_4779494_4	886293.Sinac_1477	2.938e-49	201.0	COG1073@1|root,COG1073@2|Bacteria,2IYBP@203682|Planctomycetes	203682|Planctomycetes	S	BAAT / Acyl-CoA thioester hydrolase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4779494_1	1267535.KB906767_gene1671	3.243e-115	394.0	COG0591@1|root,COG0591@2|Bacteria	2|Bacteria	E	symporter activity	-	-	-	-	-	-	-	-	-	-	-	-	SSF
CMS1_k127_4779494_3	1267535.KB906767_gene1667	3.485e-78	276.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	ophB	-	1.3.1.64	ko:K18067	ko00624,ko01100,ko01120,ko01220,map00624,map01100,map01120,map01220	M00623	R05275	RC00386	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_4779494_2	383372.Rcas_2628	1.173e-111	376.0	COG0001@1|root,COG0001@2|Bacteria,2G7SS@200795|Chloroflexi,377Z8@32061|Chloroflexia	2|Bacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CMS1_k127_4798989_0	1307759.JOMJ01000004_gene2678	6.124e-08	66.0	COG2982@1|root,COG2982@2|Bacteria,1QA6E@1224|Proteobacteria,42PKZ@68525|delta/epsilon subdivisions,2WIQZ@28221|Deltaproteobacteria,2MACK@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	AsmA-like C-terminal region	-	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA,AsmA_2
CMS1_k127_4801996_2	880070.Cycma_2445	9.082e-94	326.0	COG0591@1|root,COG3055@1|root,COG0591@2|Bacteria,COG3055@2|Bacteria,4NEN8@976|Bacteroidetes,47UXG@768503|Cytophagia	976|Bacteroidetes	E	Sodium:solute symporter family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	Kelch_1,Kelch_5,Kelch_6,SSF
CMS1_k127_4801996_1	344747.PM8797T_02314	6.069e-155	496.0	COG3055@1|root,COG3055@2|Bacteria,2IY7R@203682|Planctomycetes	203682|Planctomycetes	E	Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1
CMS1_k127_4803254_4	743719.PaelaDRAFT_3532	8.372e-25	108.0	COG1695@1|root,COG1695@2|Bacteria,1VAKA@1239|Firmicutes,4IR4T@91061|Bacilli,276N1@186822|Paenibacillaceae	91061|Bacilli	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
CMS1_k127_4803254_5	1219084.AP014508_gene1418	5.429e-09	65.0	COG0454@1|root,COG0456@2|Bacteria,2GEC7@200918|Thermotogae	200918|Thermotogae	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS1_k127_4803254_3	1449063.JMLS01000037_gene1752	1.228e-73	258.0	COG5285@1|root,COG5285@2|Bacteria,1TXK2@1239|Firmicutes,4I6JK@91061|Bacilli,26TBN@186822|Paenibacillaceae	91061|Bacilli	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
CMS1_k127_4803254_1	1303518.CCALI_02835	4.171e-98	328.0	COG5285@1|root,COG5285@2|Bacteria	2|Bacteria	Q	dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
CMS1_k127_4803254_2	880073.Calab_1488	7.843e-89	303.0	COG1600@1|root,COG1600@2|Bacteria,2NNWV@2323|unclassified Bacteria	2|Bacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
CMS1_k127_4803254_0	1303518.CCALI_01171	2.115e-101	340.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_4811340_0	56780.SYN_02742	6.18e-81	280.0	arCOG09742@1|root,2ZBGR@2|Bacteria,1R9H3@1224|Proteobacteria,42XHN@68525|delta/epsilon subdivisions,2WT8H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4811340_1	44056.XP_009039678.1	1.647e-51	198.0	2EAN3@1|root,2SGVC@2759|Eukaryota	2759|Eukaryota	S	Platelet-activating factor acetylhydrolase, isoform II	-	-	-	-	-	-	-	-	-	-	-	-	PAF-AH_p_II
CMS1_k127_4825871_0	1121904.ARBP01000052_gene3651	5.135e-220	697.0	COG1501@1|root,COG1501@2|Bacteria,4NH0T@976|Bacteroidetes,47TMI@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolases family 31	-	-	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	Glyco_hydro_31
CMS1_k127_4825871_1	1122915.AUGY01000059_gene245	9.025e-147	486.0	COG3250@1|root,COG3250@2|Bacteria,1TTVZ@1239|Firmicutes,4IQXR@91061|Bacilli,276JQ@186822|Paenibacillaceae	91061|Bacilli	G	alpha-L-rhamnosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106
CMS1_k127_4825871_2	42256.RradSPS_3030	3.396e-50	190.0	COG0371@1|root,COG0371@2|Bacteria,2HRTP@201174|Actinobacteria,4CTX5@84995|Rubrobacteria	84995|Rubrobacteria	C	COG COG0371 Glycerol dehydrogenase and related enzymes Energy production and conversion	-	-	1.1.1.261	ko:K00096	ko00564,map00564	-	R05679,R05680	RC00029	ko00000,ko00001,ko01000	-	-	-	Fe-ADH_2
CMS1_k127_4827889_2	344747.PM8797T_10954	7.725e-75	253.0	COG0673@1|root,COG0673@2|Bacteria,2IWX9@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_4827889_4	1121904.ARBP01000026_gene695	1.01e-55	205.0	COG1082@1|root,COG1082@2|Bacteria,4PP2T@976|Bacteroidetes,47VBM@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS1_k127_4827889_0	583355.Caka_0551	1.152e-116	390.0	COG0673@1|root,COG0673@2|Bacteria,46TMZ@74201|Verrucomicrobia,3K8Y2@414999|Opitutae	414999|Opitutae	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_4827889_6	935845.JADQ01000043_gene3097	1.324e-21	106.0	COG4977@1|root,COG4977@2|Bacteria,1VBP7@1239|Firmicutes,4HKCT@91061|Bacilli,277J8@186822|Paenibacillaceae	91061|Bacilli	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
CMS1_k127_4827889_1	1121438.JNJA01000011_gene1820	5.179e-82	289.0	COG0001@1|root,COG1861@1|root,COG0001@2|Bacteria,COG1861@2|Bacteria,1MUY5@1224|Proteobacteria,42NVU@68525|delta/epsilon subdivisions,2WMH6@28221|Deltaproteobacteria,2MARK@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.111,5.4.3.8	ko:K01845,ko:K07257,ko:K21585	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272,R11607	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3,CTP_transf_3
CMS1_k127_4827889_8	247490.KSU1_C1333	1.842e-16	91.0	COG4968@1|root,COG4968@2|Bacteria,2J519@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CMS1_k127_4827889_3	1267535.KB906767_gene1671	9.139e-64	241.0	COG0591@1|root,COG0591@2|Bacteria	2|Bacteria	E	symporter activity	-	-	-	-	-	-	-	-	-	-	-	-	SSF
CMS1_k127_4828628_3	118163.Ple7327_3142	3.199e-56	202.0	COG1881@1|root,COG1881@2|Bacteria,1G5SZ@1117|Cyanobacteria,3VN4P@52604|Pleurocapsales	1117|Cyanobacteria	G	Raf kinase inhibitor-like protein, YbhB YbcL family	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
CMS1_k127_4828628_1	335543.Sfum_0829	3.986e-138	453.0	COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,42MY6@68525|delta/epsilon subdivisions,2WMDC@28221|Deltaproteobacteria,2MREJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM Alcohol dehydrogenase	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_4828628_6	243164.DET1552	0.0001312	47.0	COG1961@1|root,COG1961@2|Bacteria,2G7BH@200795|Chloroflexi,34DMJ@301297|Dehalococcoidia	301297|Dehalococcoidia	L	Recombinase zinc beta ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
CMS1_k127_4828628_0	1150600.ADIARSV_0055	5.325e-236	753.0	28MHM@1|root,2ZAUH@2|Bacteria,4NKMG@976|Bacteroidetes,1IWWX@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4828628_2	247490.KSU1_C1104	1.045e-92	334.0	COG0823@1|root,COG3291@1|root,COG3828@1|root,COG0823@2|Bacteria,COG3291@2|Bacteria,COG3828@2|Bacteria,2J1GZ@203682|Planctomycetes	203682|Planctomycetes	U	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD
CMS1_k127_4828628_5	673860.AciM339_0522	1.573e-07	65.0	arCOG02499@1|root,arCOG02550@1|root,arCOG02499@2157|Archaea,arCOG02550@2157|Archaea	2157|Archaea	S	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,NosD,PKD,Pkinase
CMS1_k127_4828628_4	153721.MYP_1769	9.662e-11	70.0	COG3356@1|root,COG3356@2|Bacteria,4NGDG@976|Bacteroidetes,47JVE@768503|Cytophagia	976|Bacteroidetes	S	Neutral/alkaline non-lysosomal ceramidase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
CMS1_k127_4856740_0	1031288.AXAA01000001_gene2272	8.585e-156	503.0	COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,248EU@186801|Clostridia,36E8W@31979|Clostridiaceae	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
CMS1_k127_4856740_10	1484479.DI14_03550	1.546e-22	101.0	COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,4HKNN@91061|Bacilli,3WF05@539002|Bacillales incertae sedis	91061|Bacilli	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
CMS1_k127_4856740_11	1158345.JNLL01000001_gene65	2.505e-20	92.0	COG1837@1|root,COG1837@2|Bacteria,2G4BD@200783|Aquificae	200783|Aquificae	S	Belongs to the UPF0109 family	-	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
CMS1_k127_4856740_12	1128421.JAGA01000003_gene3608	3.004e-13	76.0	COG0806@1|root,COG0806@2|Bacteria,2NPUX@2323|unclassified Bacteria	2|Bacteria	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
CMS1_k127_4856740_3	1121423.JONT01000009_gene1470	1.096e-79	273.0	COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,247JF@186801|Clostridia,260JP@186807|Peptococcaceae	186801|Clostridia	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
CMS1_k127_4856740_9	289377.HL41_01440	2.031e-36	142.0	COG0335@1|root,COG0335@2|Bacteria,2GHWV@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
CMS1_k127_4856740_4	1120973.AQXL01000128_gene2883	3.681e-57	210.0	COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,4HB7M@91061|Bacilli,278C3@186823|Alicyclobacillaceae	91061|Bacilli	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
CMS1_k127_4856740_5	56780.SYN_00192	1.037e-45	185.0	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,42P5H@68525|delta/epsilon subdivisions,2WKAU@28221|Deltaproteobacteria,2MR1G@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Anaphase-promoting complex, cyclosome, subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_7,TPR_8
CMS1_k127_4856740_7	574087.Acear_1714	3.173e-40	157.0	COG0494@1|root,COG0494@2|Bacteria,1V6F5@1239|Firmicutes,24JFS@186801|Clostridia,3WATJ@53433|Halanaerobiales	186801|Clostridia	L	pfam nudix	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS05505	NUDIX
CMS1_k127_4856740_8	754476.Q7A_1437	1.215e-36	151.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_12,Methyltransf_25
CMS1_k127_4856740_1	1123242.JH636434_gene5500	1.507e-143	485.0	COG1621@1|root,COG1621@2|Bacteria,2J36G@203682|Planctomycetes	203682|Planctomycetes	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4856740_6	344747.PM8797T_22923	1.271e-41	176.0	COG1506@1|root,COG1506@2|Bacteria,2J3C9@203682|Planctomycetes	203682|Planctomycetes	E	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
CMS1_k127_4856740_2	1463854.JOHT01000033_gene2625	1.864e-91	315.0	COG0399@1|root,COG0399@2|Bacteria,2GKD7@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
CMS1_k127_4856740_14	756272.Plabr_0349	4.162e-06	58.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CMS1_k127_4857738_5	765911.Thivi_2192	4.712e-67	244.0	COG0446@1|root,COG0446@2|Bacteria,1QXK6@1224|Proteobacteria,1T3DN@1236|Gammaproteobacteria,1WXJD@135613|Chromatiales	135613|Chromatiales	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
CMS1_k127_4857738_7	1396418.BATQ01000134_gene4108	1.217e-43	171.0	COG0657@1|root,COG0657@2|Bacteria,46VAH@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
CMS1_k127_4857738_0	903818.KI912268_gene1318	9.489e-172	552.0	COG0702@1|root,COG0702@2|Bacteria,3Y7DF@57723|Acidobacteria	57723|Acidobacteria	GM	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10
CMS1_k127_4857738_1	1177928.TH2_17659	3.201e-133	441.0	COG3046@1|root,COG3046@2|Bacteria,1MUHX@1224|Proteobacteria,2TQP6@28211|Alphaproteobacteria,2JP9G@204441|Rhodospirillales	204441|Rhodospirillales	S	Deoxyribodipyrimidine photo-lyase-related protein	-	-	-	ko:K06876	-	-	-	-	ko00000	-	-	-	DPRP
CMS1_k127_4857738_2	886293.Sinac_6975	6.401e-130	434.0	28KPG@1|root,2ZA7K@2|Bacteria,2J1E2@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4857738_6	218284.CCDN010000002_gene2887	2.434e-60	222.0	COG0385@1|root,COG0385@2|Bacteria,1TP85@1239|Firmicutes,4HBG6@91061|Bacilli,1ZB6V@1386|Bacillus	91061|Bacilli	S	-transporter	yocS	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	iYO844.BSU19350	SBF
CMS1_k127_4857738_4	240016.ABIZ01000001_gene253	8.659e-68	252.0	COG0591@1|root,COG0591@2|Bacteria,46UFJ@74201|Verrucomicrobia,2IVV1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
CMS1_k127_4857738_3	497964.CfE428DRAFT_3508	3.18e-73	278.0	COG1621@1|root,COG1621@2|Bacteria,46T0U@74201|Verrucomicrobia	74201|Verrucomicrobia	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4857738_8	344747.PM8797T_22903	6.204e-31	142.0	COG1621@1|root,COG1621@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 32 family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,HTH_18
CMS1_k127_4857738_9	429009.Adeg_1380	2.42e-25	109.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,42EKB@68295|Thermoanaerobacterales	186801|Clostridia	E	PFAM aminotransferase, class I	aspB	-	2.6.1.1	ko:K00812,ko:K10907	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	iHN637.CLJU_RS06550	Aminotran_1_2
CMS1_k127_48709_1	768670.Calni_1182	4.462e-56	201.0	COG1898@1|root,COG1898@2|Bacteria,2GGET@200930|Deferribacteres	200930|Deferribacteres	G	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
CMS1_k127_48709_2	439235.Dalk_1695	8.178e-55	200.0	COG0279@1|root,COG0279@2|Bacteria,1NVIE@1224|Proteobacteria,43AR0@68525|delta/epsilon subdivisions,2X64X@28221|Deltaproteobacteria,2MKET@213118|Desulfobacterales	28221|Deltaproteobacteria	G	SIS domain	-	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
CMS1_k127_48709_0	639030.JHVA01000001_gene356	7.63e-115	377.0	COG0451@1|root,COG0451@2|Bacteria,3Y3T4@57723|Acidobacteria,2JIDC@204432|Acidobacteriia	204432|Acidobacteriia	M	GDP-mannose 4,6 dehydratase	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
CMS1_k127_4887554_6	522306.CAP2UW1_4251	5.005e-37	146.0	2EBIG@1|root,335IZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4887554_0	1121904.ARBP01000010_gene2227	4.675e-158	511.0	2DBQR@1|root,2ZAG2@2|Bacteria,4NK84@976|Bacteroidetes,47NS0@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2
CMS1_k127_4887554_1	411902.CLOBOL_07057	4.955e-158	543.0	COG3250@1|root,COG3250@2|Bacteria,1W77V@1239|Firmicutes,25J0P@186801|Clostridia,222YU@1506553|Lachnoclostridium	186801|Clostridia	G	alpha-L-rhamnosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106
CMS1_k127_4887554_7	1121481.AUAS01000005_gene1948	2.999e-20	98.0	COG2905@1|root,COG2905@2|Bacteria,4NP1Y@976|Bacteroidetes,47PPN@768503|Cytophagia	976|Bacteroidetes	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
CMS1_k127_4887554_4	886293.Sinac_6279	2.266e-41	156.0	COG3682@1|root,COG3682@2|Bacteria,2J0QT@203682|Planctomycetes	203682|Planctomycetes	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
CMS1_k127_4887554_3	861299.J421_1461	7.734e-43	179.0	COG4219@1|root,COG4219@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,HEAT_2,Peptidase_M56,Secretin,TonB_C
CMS1_k127_4887554_2	1303518.CCALI_00294	5.561e-134	468.0	COG4354@1|root,COG4354@2|Bacteria	2|Bacteria	G	intracellular protein transport	-	-	-	-	-	-	-	-	-	-	-	-	DUF608,Glyco_hydr_116N
CMS1_k127_4887554_5	358823.DF19_34980	1.226e-37	165.0	COG1621@1|root,COG1621@2|Bacteria,2GJ9T@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 32 family	-	-	3.2.1.65,3.2.1.80	ko:K01212,ko:K03332	ko00051,ko00500,map00051,map00500	-	R00879,R05624,R11311	RC03278	ko00000,ko00001,ko01000	-	GH32	-	Glyco_hydro_32C,Glyco_hydro_32N
CMS1_k127_4887554_9	55529.EKX37385	6.08e-05	57.0	28U2G@1|root,2R0T2@2759|Eukaryota	2759|Eukaryota	-	-	-	-	3.2.1.45	ko:K17108	ko00511,ko00600,ko01100,map00511,map00600,map01100	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH116	-	DUF608,Glyco_hydr_116N
CMS1_k127_4891067_0	344747.PM8797T_26585	5.519e-245	781.0	COG2010@1|root,COG2010@2|Bacteria,2J53S@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
CMS1_k127_4891067_1	240016.ABIZ01000001_gene1559	2.34e-221	695.0	COG4102@1|root,COG4102@2|Bacteria,46UQM@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
CMS1_k127_4891067_4	105559.Nwat_2072	3.53e-51	194.0	COG2208@1|root,COG2208@2|Bacteria,1NZTV@1224|Proteobacteria	1224|Proteobacteria	KT	PFAM Stage II sporulation E family protein	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
CMS1_k127_4891067_2	761193.Runsl_0841	1.892e-77	269.0	COG0726@1|root,COG0726@2|Bacteria,4NJK7@976|Bacteroidetes,47MUF@768503|Cytophagia	976|Bacteroidetes	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
CMS1_k127_4891067_3	344747.PM8797T_10254	2.206e-56	206.0	COG2755@1|root,COG2755@2|Bacteria,2IZAF@203682|Planctomycetes	203682|Planctomycetes	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS1_k127_4894496_0	1444712.BN1013_00448	1.01e-67	247.0	COG2801@1|root,COG2801@2|Bacteria,2JGKD@204428|Chlamydiae	2|Bacteria	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_23,HTH_28,HTH_32,HTH_8,rve,rve_3
CMS1_k127_4894667_9	330214.NIDE1579	6.64e-68	240.0	COG0285@1|root,COG0285@2|Bacteria,3J0I6@40117|Nitrospirae	40117|Nitrospirae	H	Mur ligase middle domain	-	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
CMS1_k127_4894667_8	221360.RS9917_12085	1.018e-81	280.0	COG0777@1|root,COG0777@2|Bacteria,1G1ZY@1117|Cyanobacteria,1GZU0@1129|Synechococcus	1117|Cyanobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	iJN678.accD	Carboxyl_trans
CMS1_k127_4894667_16	1123371.ATXH01000020_gene478	6.851e-24	110.0	COG1579@1|root,COG1579@2|Bacteria,2GH3N@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	C4-type zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
CMS1_k127_4894667_19	880073.Calab_0396	6.356e-09	57.0	COG0059@1|root,COG0059@2|Bacteria,2NNKS@2323|unclassified Bacteria	2|Bacteria	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10005,iHN637.CLJU_RS10010,iJN746.PP_4678,iLJ478.TM0550	IlvC,IlvN
CMS1_k127_4894667_11	1499967.BAYZ01000122_gene3365	1.152e-60	214.0	COG0440@1|root,COG0440@2|Bacteria,2NPPK@2323|unclassified Bacteria	2|Bacteria	E	ACT domain	ilvH	GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_1906,iECNA114_1301.ECNA114_0072,iEcSMS35_1347.EcSMS35_0084,iG2583_1286.G2583_0082,iSFxv_1172.SFxv_0077,iUTI89_1310.UTI89_C0086	ACT,ACT_5,ALS_ss_C
CMS1_k127_4894667_12	861454.HMPREF9099_02961	5.458e-54	196.0	COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,24HMC@186801|Clostridia,27MET@186928|unclassified Lachnospiraceae	186801|Clostridia	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
CMS1_k127_4894667_14	926561.KB900617_gene2256	6.971e-41	159.0	COG1825@1|root,COG1825@2|Bacteria,1VA38@1239|Firmicutes,24N24@186801|Clostridia,3WBPT@53433|Halanaerobiales	186801|Clostridia	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
CMS1_k127_4894667_2	1340493.JNIF01000004_gene1001	1.697e-113	374.0	COG0462@1|root,COG0462@2|Bacteria,3Y3KV@57723|Acidobacteria	57723|Acidobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
CMS1_k127_4894667_22	981223.AIED01000164_gene463	0.0007961	44.0	2AZTC@1|root,31S2K@2|Bacteria,1QPJP@1224|Proteobacteria,1TNA5@1236|Gammaproteobacteria,3NQ8M@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4894667_6	1403819.BATR01000118_gene4191	2.684e-87	299.0	COG1172@1|root,COG1172@2|Bacteria,46V1Z@74201|Verrucomicrobia,2IVHK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
CMS1_k127_4894667_5	661478.OP10G_1297	4.579e-99	333.0	COG1879@1|root,COG1879@2|Bacteria	2|Bacteria	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
CMS1_k127_4894667_7	1267535.KB906767_gene1026	6.502e-86	303.0	COG0673@1|root,COG0673@2|Bacteria,3Y6VS@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_4894667_21	641524.ADICYQ_4319	0.0001297	53.0	COG2885@1|root,COG2885@2|Bacteria,4NRQ3@976|Bacteroidetes,47QE9@768503|Cytophagia	976|Bacteroidetes	M	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
CMS1_k127_4894667_0	717605.Theco_0989	7.155e-230	724.0	COG1069@1|root,COG1069@2|Bacteria,1TP8T@1239|Firmicutes,4HC3A@91061|Bacilli,26TUS@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the ribulokinase family	araB	-	2.7.1.16	ko:K00853	ko00040,ko01100,map00040,map01100	-	R01526,R02439	RC00002,RC00538	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
CMS1_k127_4894667_4	1210884.HG799467_gene13285	4.423e-108	361.0	COG1363@1|root,COG1363@2|Bacteria,2IXMY@203682|Planctomycetes	203682|Planctomycetes	G	COG1363 Cellulase M and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
CMS1_k127_4894667_10	435591.BDI_2877	9.296e-61	218.0	COG0363@1|root,COG0363@2|Bacteria,4NPBJ@976|Bacteroidetes,2FNEN@200643|Bacteroidia	976|Bacteroidetes	G	COG0363 6-phosphogluconolactonase Glucosamine-6-phosphate isomerase deaminase	-	-	3.5.99.6	ko:K02080,ko:K02564	ko00052,ko00520,ko01100,map00052,map00520,map01100	-	R00765,R08365	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso
CMS1_k127_4894667_15	926560.KE387027_gene844	1.232e-35	145.0	COG3714@1|root,COG3714@2|Bacteria,1WNCT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	YhhN family	-	-	-	-	-	-	-	-	-	-	-	-	YhhN
CMS1_k127_4894667_13	1403819.BATR01000149_gene5058	1.152e-53	208.0	COG1621@1|root,COG1621@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 32 family	-	-	3.1.3.6,3.1.4.16	ko:K01119	ko00230,ko00240,map00230,map00240	-	R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135	RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	SLH
CMS1_k127_4894667_20	1121439.dsat_0476	1.189e-05	59.0	COG0457@1|root,COG0457@2|Bacteria,1QQUW@1224|Proteobacteria,43E95@68525|delta/epsilon subdivisions,2X01P@28221|Deltaproteobacteria,2M9TS@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Bacteriophage N adsorption protein A C-term	-	-	-	-	-	-	-	-	-	-	-	-	NfrA_C,TPR_16,TPR_19,TPR_2,TPR_8
CMS1_k127_4894667_3	616991.JPOO01000003_gene2396	1.294e-112	373.0	COG0329@1|root,COG0329@2|Bacteria,4NI1I@976|Bacteroidetes,1I799@117743|Flavobacteriia	976|Bacteroidetes	EM	Dihydrodipicolinate synthetase family	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
CMS1_k127_4894667_17	1150600.ADIARSV_2768	6.145e-21	101.0	COG1309@1|root,COG1309@2|Bacteria,4NUB3@976|Bacteroidetes,1ITPE@117747|Sphingobacteriia	976|Bacteroidetes	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_4,TetR_N
CMS1_k127_4894667_1	1304874.JAFY01000002_gene661	2.348e-172	556.0	COG0477@1|root,COG2814@2|Bacteria,3TACG@508458|Synergistetes	508458|Synergistetes	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_4894667_18	867845.KI911784_gene3737	4.642e-17	87.0	COG1595@1|root,COG1595@2|Bacteria,2G6T5@200795|Chloroflexi,375JF@32061|Chloroflexia	32061|Chloroflexia	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_4894823_0	756272.Plabr_4659	8.209e-30	124.0	COG1131@1|root,COG1131@2|Bacteria,2IXFI@203682|Planctomycetes	203682|Planctomycetes	V	ABC-type multidrug transport system ATPase	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_4894823_1	344747.PM8797T_28989	5.523e-06	59.0	2DUSB@1|root,33S06@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4897717_1	760192.Halhy_3867	5.534e-20	96.0	COG0792@1|root,COG0792@2|Bacteria,4NS7E@976|Bacteroidetes,1ITMT@117747|Sphingobacteriia	976|Bacteroidetes	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
CMS1_k127_4897717_0	404380.Gbem_2297	8.476e-43	168.0	COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,42RG5@68525|delta/epsilon subdivisions,2WNRE@28221|Deltaproteobacteria,43SVJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
CMS1_k127_4897717_3	1347393.HG726029_gene2070	5.558e-10	72.0	COG3049@1|root,COG3049@2|Bacteria,4PKMY@976|Bacteroidetes,2FPKS@200643|Bacteroidia,4AP75@815|Bacteroidaceae	976|Bacteroidetes	M	Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	AAT
CMS1_k127_4897717_2	742766.HMPREF9455_02079	2.142e-12	80.0	COG3356@1|root,COG3356@2|Bacteria,4NU9C@976|Bacteroidetes,2FRG0@200643|Bacteroidia,2315T@171551|Porphyromonadaceae	976|Bacteroidetes	S	PFAM Neutral alkaline nonlysosomal ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
CMS1_k127_4900234_0	278963.ATWD01000001_gene2651	5.63e-30	132.0	299CW@1|root,2ZWFT@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4900234_1	670307.HYPDE_37458	7.566e-29	117.0	COG3677@1|root,COG3677@2|Bacteria,1MXYX@1224|Proteobacteria,2TQR3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
CMS1_k127_4900234_2	460265.Mnod_8816	3.757e-28	121.0	COG1675@1|root,COG1675@2|Bacteria,1MZ5R@1224|Proteobacteria,2UMKV@28211|Alphaproteobacteria,1JWSH@119045|Methylobacteriaceae	28211|Alphaproteobacteria	K	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4904296_1	1300150.EMQU_0667	4.211e-52	187.0	COG0590@1|root,COG0590@2|Bacteria,1V3HZ@1239|Firmicutes,4HH7S@91061|Bacilli,4B2BB@81852|Enterococcaceae	91061|Bacilli	F	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	GO:0002097,GO:0002100,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
CMS1_k127_4904296_3	497964.CfE428DRAFT_0414	1.114e-31	136.0	COG0589@1|root,COG0589@2|Bacteria,46T47@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS1_k127_4904296_0	321327.CYA_1027	2.19e-52	194.0	COG0229@1|root,COG0229@2|Bacteria,1G5S6@1117|Cyanobacteria,1H490@1129|Synechococcus	1117|Cyanobacteria	C	SelR domain	-	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
CMS1_k127_4904296_2	552811.Dehly_0510	2.082e-34	133.0	COG1193@1|root,COG1193@2|Bacteria,2G9VU@200795|Chloroflexi,34DGU@301297|Dehalococcoidia	301297|Dehalococcoidia	L	Smr domain	-	-	-	-	-	-	-	-	-	-	-	-	Smr
CMS1_k127_4904296_4	715226.ABI_30530	1.261e-24	112.0	COG2133@1|root,COG2133@2|Bacteria,1RHI4@1224|Proteobacteria,2UF03@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CMS1_k127_490579_1	530564.Psta_4238	1.856e-23	111.0	COG2755@1|root,COG3507@1|root,COG2755@2|Bacteria,COG3507@2|Bacteria,2IXFZ@203682|Planctomycetes	203682|Planctomycetes	E	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CMS1_k127_490579_0	204669.Acid345_2620	1.316e-93	319.0	COG0773@1|root,COG0773@2|Bacteria,3Y2M2@57723|Acidobacteria,2JIE2@204432|Acidobacteriia	204432|Acidobacteriia	M	Mur ligase middle domain	-	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS1_k127_490755_4	591158.SSMG_05501	1.871e-09	59.0	2DSQW@1|root,33H3S@2|Bacteria,2GTIV@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_490755_2	948565.AFFP02000054_gene23	4.241e-21	94.0	2DPM9@1|root,332MQ@2|Bacteria,1NAPW@1224|Proteobacteria,1SDC6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_490755_3	1125701.HMPREF1221_00764	2.447e-17	83.0	2DPM9@1|root,332MQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_490755_5	411467.BACCAP_03832	4.946e-08	55.0	2DN97@1|root,32W7A@2|Bacteria,1VANB@1239|Firmicutes,24Q9J@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_490755_0	1131269.AQVV01000018_gene1940	3.321e-34	132.0	2DPX5@1|root,333S8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_490755_1	566461.SSFG_05974	1.622e-25	106.0	2DMHR@1|root,32RMI@2|Bacteria,2HC0U@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4923854_4	575540.Isop_1746	1.201e-17	93.0	COG0667@1|root,COG0667@2|Bacteria,2J2CM@203682|Planctomycetes	203682|Planctomycetes	C	PFAM Aldo keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS1_k127_4923854_0	1238450.VIBNISOn1_450065	8.873e-99	334.0	COG2128@1|root,COG2128@2|Bacteria	2|Bacteria	S	hydroperoxide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD,DUF3179
CMS1_k127_4923854_3	1123242.JH636434_gene5272	2.241e-33	146.0	COG1621@1|root,COG1621@2|Bacteria,2IY26@203682|Planctomycetes	2|Bacteria	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Dockerin_1,HTH_18,RicinB_lectin_2
CMS1_k127_4923854_1	880070.Cycma_4737	4.293e-97	342.0	COG5434@1|root,COG5434@2|Bacteria,4NG62@976|Bacteroidetes,47TF7@768503|Cytophagia	976|Bacteroidetes	M	Heparinase II/III N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_lyase,Beta_helix,Hepar_II_III,Hepar_II_III_N
CMS1_k127_4923854_2	1267535.KB906767_gene1240	5.839e-35	154.0	COG1572@1|root,COG1572@2|Bacteria,3Y8B5@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4091)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4091
CMS1_k127_4923854_5	448385.sce5810	0.0003421	54.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Big_2,CBM_25,Calx-beta,DUF4114,P_proprotein,Peptidase_S8,SBBP,SLH,VCBS
CMS1_k127_4926079_2	56110.Oscil6304_5747	5.266e-27	117.0	COG2402@1|root,COG2402@2|Bacteria,1G8Q4@1117|Cyanobacteria,1HDF7@1150|Oscillatoriales	1117|Cyanobacteria	S	contains PIN domain	-	-	-	ko:K07065	-	-	-	-	ko00000	-	-	-	PIN
CMS1_k127_4926079_4	1396141.BATP01000057_gene2994	2.767e-10	73.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	-	ko:K12678	-	-	-	-	ko00000,ko02000,ko02044	1.B.12.1.1,1.B.12.1.3	-	-	-
CMS1_k127_4926079_0	595460.RRSWK_00504	1.216e-55	208.0	COG0628@1|root,COG0628@2|Bacteria,2J103@203682|Planctomycetes	203682|Planctomycetes	S	membrane protein-putative a permease	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
CMS1_k127_4926079_1	886293.Sinac_5740	8.039e-50	182.0	COG2755@1|root,COG2755@2|Bacteria,2IYFC@203682|Planctomycetes	203682|Planctomycetes	E	Domain of unknown function (DUF3472)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3472,DUF5077
CMS1_k127_4926139_2	661478.OP10G_1192	1.959e-12	80.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
CMS1_k127_4926139_1	1033737.CAEV01000056_gene3697	3.784e-60	230.0	COG0535@1|root,COG0535@2|Bacteria,1TR52@1239|Firmicutes,247SB@186801|Clostridia,36E8H@31979|Clostridiaceae	186801|Clostridia	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
CMS1_k127_4926139_0	886293.Sinac_3781	1.281e-153	501.0	COG3356@1|root,COG3356@2|Bacteria,2IYM3@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Neutral alkaline nonlysosomal ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4931666_4	1116375.VEJY3_08760	3.134e-28	122.0	COG0438@1|root,COG0438@2|Bacteria,1QU2N@1224|Proteobacteria,1RYA1@1236|Gammaproteobacteria,1XSMY@135623|Vibrionales	135623|Vibrionales	M	COG0438 Glycosyltransferase	VP1463	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
CMS1_k127_4931666_0	1313304.CALK_1748	1.867e-153	493.0	COG0381@1|root,COG0381@2|Bacteria	2|Bacteria	M	UDP-N-acetylglucosamine 2-epimerase activity	-	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
CMS1_k127_4931666_1	1254432.SCE1572_48695	2.452e-111	376.0	COG1696@1|root,COG1696@2|Bacteria,1MUXN@1224|Proteobacteria,42MIR@68525|delta/epsilon subdivisions,2WMEK@28221|Deltaproteobacteria,2YU2I@29|Myxococcales	28221|Deltaproteobacteria	M	MBOAT, membrane-bound O-acyltransferase family	algI	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
CMS1_k127_4931666_2	1267533.KB906737_gene1525	3.685e-65	236.0	2ACTX@1|root,312EV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4931666_3	1869.MB27_07295	6.192e-44	176.0	COG5653@1|root,COG5653@2|Bacteria	2|Bacteria	M	Protein involved in cellulose biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6,FemAB
CMS1_k127_4967278_1	1205680.CAKO01000002_gene2295	3.093e-07	52.0	COG2128@1|root,COG2128@2|Bacteria,1RD1K@1224|Proteobacteria,2U6ZZ@28211|Alphaproteobacteria,2JU9D@204441|Rhodospirillales	204441|Rhodospirillales	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS1_k127_4967278_0	1121957.ATVL01000009_gene1369	5.079e-181	582.0	COG4805@1|root,COG4805@2|Bacteria,4NFAK@976|Bacteroidetes,47MIN@768503|Cytophagia	976|Bacteroidetes	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
CMS1_k127_4969317_0	867903.ThesuDRAFT_02165	3.707e-93	312.0	COG1028@1|root,COG1028@2|Bacteria,1TQZW@1239|Firmicutes,249T4@186801|Clostridia	186801|Clostridia	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS1_k127_4969317_1	1123242.JH636434_gene3281	2.344e-52	188.0	COG1024@1|root,COG1024@2|Bacteria,2IZFF@203682|Planctomycetes	203682|Planctomycetes	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS1_k127_497050_0	706587.Desti_2509	9.65e-111	366.0	COG0457@1|root,COG1413@1|root,COG0457@2|Bacteria,COG1413@2|Bacteria,1MX2U@1224|Proteobacteria,42QJC@68525|delta/epsilon subdivisions,2WPI2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,HEAT_2,Paired_CXXCH_1,TPR_10,TPR_16,TPR_19,TPR_4,TPR_8
CMS1_k127_497050_1	497964.CfE428DRAFT_5894	1.677e-98	325.0	COG3119@1|root,COG3119@2|Bacteria,46U45@74201|Verrucomicrobia	2|Bacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CMS1_k127_4983604_1	1236959.BAMT01000001_gene1153	3.489e-13	76.0	2DQZQ@1|root,339JR@2|Bacteria,1NNI2@1224|Proteobacteria,2W5R6@28216|Betaproteobacteria,2KN9M@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4983604_0	298654.FraEuI1c_0484	6.491e-57	211.0	COG3509@1|root,COG3509@2|Bacteria,2GNV6@201174|Actinobacteria,4EU0N@85013|Frankiales	201174|Actinobacteria	Q	Esterase PHB depolymerase	lpqC	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Esterase_phd
CMS1_k127_4983833_4	497964.CfE428DRAFT_1757	9.689e-05	53.0	COG1520@1|root,COG3055@1|root,COG1520@2|Bacteria,COG3055@2|Bacteria,46TNK@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CMS1_k127_4983833_3	1131730.BAVI_10999	5.116e-30	138.0	COG1472@1|root,COG1472@2|Bacteria,1TP63@1239|Firmicutes,4HBDB@91061|Bacilli,1ZCGR@1386|Bacillus	91061|Bacilli	G	Belongs to the glycosyl hydrolase 3 family	nagZ	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4309,Glyco_hydro_3
CMS1_k127_4983833_0	1125863.JAFN01000001_gene674	3.373e-283	884.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,42MFA@68525|delta/epsilon subdivisions,2WJ20@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
CMS1_k127_4983833_1	555079.Toce_1364	5.596e-183	593.0	COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,2489A@186801|Clostridia,42F3U@68295|Thermoanaerobacterales	186801|Clostridia	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS16615	ACT_4,HD_4,RelA_SpoT,TGS
CMS1_k127_4983833_2	1304880.JAGB01000002_gene1701	7.031e-88	299.0	COG1397@1|root,COG1397@2|Bacteria,1TSKF@1239|Firmicutes,25DA4@186801|Clostridia	186801|Clostridia	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
CMS1_k127_4989634_21	71139.XP_010044075.1	5.359e-07	63.0	2CMU7@1|root,2QRZ6@2759|Eukaryota,37MS8@33090|Viridiplantae,3GF9D@35493|Streptophyta	35493|Streptophyta	S	Defective in exine formation	-	GO:0003674,GO:0005488,GO:0005509,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0007275,GO:0008150,GO:0009555,GO:0009653,GO:0009987,GO:0010208,GO:0010584,GO:0010927,GO:0012505,GO:0016020,GO:0016043,GO:0022607,GO:0030198,GO:0032501,GO:0032502,GO:0032989,GO:0043062,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0045229,GO:0046872,GO:0048229,GO:0048646,GO:0048856,GO:0048869,GO:0071840,GO:0085029	-	-	-	-	-	-	-	-	-	-	FG-GAP,VCBS
CMS1_k127_4989634_18	1408813.AYMG01000021_gene1107	8.89e-28	132.0	COG0726@1|root,COG0726@2|Bacteria,4NE92@976|Bacteroidetes,1IUV7@117747|Sphingobacteriia	976|Bacteroidetes	G	Cellulase N-terminal ig-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CelD_N,Glyco_hydro_9
CMS1_k127_4989634_16	189425.PGRAT_16360	2.236e-29	130.0	COG1409@1|root,COG1409@2|Bacteria,1U2MN@1239|Firmicutes,4HB87@91061|Bacilli,27512@186822|Paenibacillaceae	91061|Bacilli	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
CMS1_k127_4989634_19	382464.ABSI01000005_gene950	1.555e-24	119.0	COG1538@1|root,COG1538@2|Bacteria,46T0P@74201|Verrucomicrobia	74201|Verrucomicrobia	MU	PFAM outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
CMS1_k127_4989634_15	234267.Acid_0701	2.628e-30	136.0	COG1413@1|root,COG1413@2|Bacteria,3Y7N7@57723|Acidobacteria	57723|Acidobacteria	C	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CMS1_k127_4989634_12	344747.PM8797T_30449	7.293e-43	169.0	294P7@1|root,2ZS2I@2|Bacteria,2J4KK@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4989634_5	518766.Rmar_1923	2.971e-116	386.0	COG0494@1|root,COG1194@1|root,COG0494@2|Bacteria,COG1194@2|Bacteria,4NDZY@976|Bacteroidetes,1FISB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	NUDIX domain	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
CMS1_k127_4989634_3	382464.ABSI01000011_gene2609	3.829e-140	458.0	COG3119@1|root,COG3119@2|Bacteria,46UET@74201|Verrucomicrobia,2IU4V@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	C-terminal region of aryl-sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,Sulfatase_C
CMS1_k127_4989634_4	1449063.JMLS01000004_gene2781	3.46e-123	407.0	COG3669@1|root,COG3669@2|Bacteria,1TQH2@1239|Firmicutes,4HDR0@91061|Bacilli,26V9U@186822|Paenibacillaceae	91061|Bacilli	G	Alpha-L-fucosidase	-	-	-	-	-	-	-	-	-	-	-	-	Alpha_L_fucos
CMS1_k127_4989634_0	1128421.JAGA01000002_gene1199	3.349e-198	632.0	COG0318@1|root,COG0318@2|Bacteria,2NPH9@2323|unclassified Bacteria	2|Bacteria	IQ	COGs COG0318 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
CMS1_k127_4989634_1	1128421.JAGA01000002_gene1199	1.89e-195	629.0	COG0318@1|root,COG0318@2|Bacteria,2NPH9@2323|unclassified Bacteria	2|Bacteria	IQ	COGs COG0318 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
CMS1_k127_4989634_7	1304880.JAGB01000002_gene1638	1.791e-85	297.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,2483J@186801|Clostridia	186801|Clostridia	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS1_k127_4989634_14	870187.Thini_3076	5.129e-35	149.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,1RN0E@1236|Gammaproteobacteria,4626C@72273|Thiotrichales	72273|Thiotrichales	M	HlyD family secretion protein	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
CMS1_k127_4989634_6	1120971.AUCA01000023_gene535	3.453e-87	295.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,4HBMF@91061|Bacilli	91061|Bacilli	V	ABC transporter, ATP-binding protein	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_4989634_11	247490.KSU1_C1018	4.411e-52	209.0	COG1538@1|root,COG1538@2|Bacteria,2IZ8Q@203682|Planctomycetes	203682|Planctomycetes	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
CMS1_k127_4989634_2	439235.Dalk_2837	1.169e-154	499.0	COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,42M9E@68525|delta/epsilon subdivisions,2WJ3F@28221|Deltaproteobacteria,2MI7I@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
CMS1_k127_4989634_20	314230.DSM3645_07246	1.172e-11	72.0	2EAFJ@1|root,334IY@2|Bacteria,2J12W@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF1844)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1844
CMS1_k127_4989634_10	984892.SPSE_1326	1.042e-52	189.0	COG0105@1|root,COG0105@2|Bacteria,1V44G@1239|Firmicutes,4HH8C@91061|Bacilli,4GYXP@90964|Staphylococcaceae	91061|Bacilli	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
CMS1_k127_4989634_17	1158762.KB898040_gene1408	3.225e-28	123.0	COG1714@1|root,COG1714@2|Bacteria,1N1XF@1224|Proteobacteria,1SDY3@1236|Gammaproteobacteria,1WZR8@135613|Chromatiales	135613|Chromatiales	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD,zinc_ribbon_2
CMS1_k127_4989634_13	1123242.JH636434_gene4245	1.044e-36	142.0	COG3795@1|root,COG3795@2|Bacteria,2J10A@203682|Planctomycetes	203682|Planctomycetes	S	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
CMS1_k127_4989634_9	391038.Bphy_4102	1.221e-58	207.0	COG3832@1|root,COG3832@2|Bacteria,1RD0P@1224|Proteobacteria,2VS78@28216|Betaproteobacteria,1K76G@119060|Burkholderiaceae	28216|Betaproteobacteria	S	PFAM Activator of Hsp90 ATPase 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
CMS1_k127_4989634_8	593750.Metfor_2797	1.032e-61	220.0	COG3832@1|root,arCOG09481@1|root,arCOG05261@2157|Archaea,arCOG09481@2157|Archaea,2XYEH@28890|Euryarchaeota,2NAYB@224756|Methanomicrobia	224756|Methanomicrobia	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
CMS1_k127_4989634_22	1123508.JH636443_gene4834	8.834e-07	50.0	COG3832@1|root,COG3832@2|Bacteria,2J11K@203682|Planctomycetes	203682|Planctomycetes	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
CMS1_k127_499799_2	1064535.MELS_0088	2.833e-49	195.0	COG1663@1|root,COG1663@2|Bacteria,1TWGA@1239|Firmicutes,4H97G@909932|Negativicutes	909932|Negativicutes	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Glycos_transf_N,LpxK
CMS1_k127_499799_1	316067.Geob_1557	1.429e-80	284.0	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,42N10@68525|delta/epsilon subdivisions,2WJI9@28221|Deltaproteobacteria,43U42@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	TIGRFAM DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
CMS1_k127_499799_0	1121904.ARBP01000003_gene6415	1.252e-179	578.0	COG3119@1|root,COG3119@2|Bacteria,4NHH7@976|Bacteroidetes,47JYR@768503|Cytophagia	976|Bacteroidetes	P	PFAM sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CMS1_k127_499799_3	886293.Sinac_2627	4.102e-15	78.0	COG4485@1|root,COG5617@1|root,COG4485@2|Bacteria,COG5617@2|Bacteria,2J236@203682|Planctomycetes	203682|Planctomycetes	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5013626_6	398767.Glov_0435	6.801e-55	216.0	COG0739@1|root,COG0739@2|Bacteria,1R9V0@1224|Proteobacteria	1224|Proteobacteria	M	COG0739 Membrane proteins related to metalloendopeptidases	-	-	-	ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
CMS1_k127_5013626_0	1121930.AQXG01000001_gene1206	1.253e-133	441.0	COG4452@1|root,COG4452@2|Bacteria,4NGKY@976|Bacteroidetes,1IPKH@117747|Sphingobacteriia	976|Bacteroidetes	V	Inner membrane protein CreD	creD	-	-	ko:K06143	-	-	-	-	ko00000	-	-	-	CreD
CMS1_k127_5013626_2	452637.Oter_1316	8.283e-121	413.0	COG0642@1|root,COG2205@2|Bacteria,46UQ3@74201|Verrucomicrobia,3K7IN@414999|Opitutae	414999|Opitutae	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K07641	ko02020,map02020	M00449	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
CMS1_k127_5013626_4	794903.OPIT5_02955	6.323e-73	252.0	COG0745@1|root,COG0745@2|Bacteria,46UGY@74201|Verrucomicrobia,3K7XC@414999|Opitutae	414999|Opitutae	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07663	ko02020,map02020	M00449	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_5013626_21	713586.KB900536_gene630	5.98e-06	52.0	COG2801@1|root,COG2801@2|Bacteria,1MZ45@1224|Proteobacteria,1RSNX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG2801 Transposase and inactivated derivatives	ylbG	-	-	-	-	-	-	-	-	-	-	-	HTH_29,rve,rve_2,rve_3
CMS1_k127_5013626_3	243231.GSU2788	1.029e-78	267.0	COG1765@1|root,COG1765@2|Bacteria,1MWPR@1224|Proteobacteria,42S3G@68525|delta/epsilon subdivisions,2WNET@28221|Deltaproteobacteria,43UXB@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
CMS1_k127_5013626_7	330214.NIDE3842	7.56e-47	173.0	COG3093@1|root,COG3093@2|Bacteria	2|Bacteria	K	addiction module antidote protein HigA	higA	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3,HTH_31
CMS1_k127_5013626_14	330214.NIDE3841	2.675e-19	88.0	COG3549@1|root,COG3549@2|Bacteria	2|Bacteria	S	RelE-like toxin of type II toxin-antitoxin system HigB	higB	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
CMS1_k127_5013626_12	706587.Desti_1731	1.089e-21	100.0	2C7QB@1|root,341QI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5013626_9	1173024.KI912149_gene6039	1.963e-31	124.0	COG3514@1|root,COG3514@2|Bacteria,1G7ND@1117|Cyanobacteria	1117|Cyanobacteria	S	SPTR CopG domain protein DNA-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BrnA_antitoxin
CMS1_k127_5013626_18	933262.AXAM01000005_gene2503	4.378e-09	57.0	COG2929@1|root,COG2929@2|Bacteria,1MZKJ@1224|Proteobacteria,42VVB@68525|delta/epsilon subdivisions,2WRMJ@28221|Deltaproteobacteria,2MP0A@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	BrnT_toxin
CMS1_k127_5013626_16	1173024.KI912149_gene6038	1.592e-10	63.0	COG2929@1|root,COG2929@2|Bacteria,1G8FA@1117|Cyanobacteria	1117|Cyanobacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
CMS1_k127_5013626_10	177437.HRM2_39830	5.2e-28	118.0	29BXV@1|root,2ZYW9@2|Bacteria,1Q57X@1224|Proteobacteria,430RM@68525|delta/epsilon subdivisions,2WVRN@28221|Deltaproteobacteria,2MNNU@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5013626_15	1125973.JNLC01000002_gene2048	1.483e-17	85.0	COG3514@1|root,COG3514@2|Bacteria,1NGCR@1224|Proteobacteria,2UFX3@28211|Alphaproteobacteria,3K0JV@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	BrnA antitoxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	BrnA_antitoxin
CMS1_k127_5013626_19	1159870.KB907784_gene744	7.796e-09	57.0	COG2929@1|root,COG2929@2|Bacteria,1N83Z@1224|Proteobacteria,2VVVC@28216|Betaproteobacteria,3T4U0@506|Alcaligenaceae	28216|Betaproteobacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
CMS1_k127_5013626_20	383407.XOC_2639	3.583e-06	49.0	COG2929@1|root,COG2929@2|Bacteria,1N83Z@1224|Proteobacteria,1SEV2@1236|Gammaproteobacteria,1XC5H@135614|Xanthomonadales	135614|Xanthomonadales	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
CMS1_k127_5013626_22	517418.Ctha_1813	1.152e-05	56.0	COG0457@1|root,COG0457@2|Bacteria	517418.Ctha_1813|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5013626_1	1304885.AUEY01000104_gene2548	1.114e-121	398.0	COG0702@1|root,COG0702@2|Bacteria,1Q438@1224|Proteobacteria,439WM@68525|delta/epsilon subdivisions,2X29K@28221|Deltaproteobacteria,2MPBK@213118|Desulfobacterales	28221|Deltaproteobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
CMS1_k127_5013626_5	316067.Geob_2819	5.054e-56	200.0	COG3034@1|root,COG3034@2|Bacteria,1MXY6@1224|Proteobacteria,42TV7@68525|delta/epsilon subdivisions,2WRW0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
CMS1_k127_5013626_8	304371.MCP_2169	3.779e-38	147.0	arCOG06069@1|root,arCOG06069@2157|Archaea,2Y06E@28890|Euryarchaeota,2NB1K@224756|Methanomicrobia	224756|Methanomicrobia	S	Putative redox-active protein (C_GCAxxG_C_C)	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
CMS1_k127_5013626_13	504472.Slin_4456	6.835e-21	94.0	COG1724@1|root,COG1724@2|Bacteria	2|Bacteria	N	mRNA binding	-	-	-	ko:K07339	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HicA_toxin
CMS1_k127_5013626_11	1283300.ATXB01000001_gene2139	8.921e-22	96.0	COG1598@1|root,COG1598@2|Bacteria,1NPTZ@1224|Proteobacteria	1224|Proteobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5016893_2	344747.PM8797T_15161	1.12e-103	355.0	COG0673@1|root,COG0673@2|Bacteria,2IXE4@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_5016893_0	880073.Calab_0640	8.055e-266	833.0	COG0591@1|root,COG0591@2|Bacteria	2|Bacteria	E	symporter activity	-	-	-	-	-	-	-	-	-	-	-	-	SSF
CMS1_k127_5016893_6	926569.ANT_26620	1.1e-69	244.0	COG0778@1|root,COG0778@2|Bacteria	2|Bacteria	C	coenzyme F420-1:gamma-L-glutamate ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CMS1_k127_5016893_7	65393.PCC7424_4306	2.139e-34	145.0	COG0667@1|root,COG0667@2|Bacteria,1G2DX@1117|Cyanobacteria,3KGHU@43988|Cyanothece	1117|Cyanobacteria	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS1_k127_5016893_4	1123278.KB893548_gene4673	2.274e-93	319.0	COG1028@1|root,COG1028@2|Bacteria,4NH6Y@976|Bacteroidetes,47JEU@768503|Cytophagia	976|Bacteroidetes	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS1_k127_5016893_3	1449126.JQKL01000003_gene1810	2.204e-103	353.0	COG1914@1|root,COG1914@2|Bacteria	2|Bacteria	P	metal ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
CMS1_k127_5016893_1	861299.J421_5606	1.948e-213	669.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	-	-	4.2.1.68	ko:K18334	ko00051,ko01120,map00051,map01120	-	R03688	RC00543	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
CMS1_k127_5016893_8	1121481.AUAS01000007_gene1192	3.552e-17	97.0	2DPJR@1|root,332DY@2|Bacteria,4NV3G@976|Bacteroidetes,47WFK@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5030872_0	1121422.AUMW01000002_gene2191	1.033e-105	351.0	COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,247JD@186801|Clostridia,260N3@186807|Peptococcaceae	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
CMS1_k127_5030872_2	373994.Riv7116_3826	0.0007843	43.0	COG3963@1|root,COG3963@2|Bacteria,1GA3R@1117|Cyanobacteria,1HNAY@1161|Nostocales	1117|Cyanobacteria	I	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
CMS1_k127_5030872_1	765952.PUV_25070	6.422e-67	244.0	COG1409@1|root,COG1409@2|Bacteria,2JFSW@204428|Chlamydiae	204428|Chlamydiae	S	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
CMS1_k127_5033736_10	497964.CfE428DRAFT_5505	1.191e-68	246.0	COG3391@1|root,COG3391@2|Bacteria,46SN2@74201|Verrucomicrobia	74201|Verrucomicrobia	M	phospholipase C	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase,Phosphoesterase
CMS1_k127_5033736_12	397945.Aave_4238	1.743e-50	201.0	COG0265@1|root,COG0265@2|Bacteria,1R61I@1224|Proteobacteria,2VP90@28216|Betaproteobacteria,4ACQ1@80864|Comamonadaceae	28216|Betaproteobacteria	O	peptidase S1 and S6, chymotrypsin Hap	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Trypsin,Trypsin_2
CMS1_k127_5033736_3	485913.Krac_5736	4.992e-192	644.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2G7P2@200795|Chloroflexi	200795|Chloroflexi	KLT	SMART serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_16,TPR_2,TPR_8,WD40
CMS1_k127_5033736_16	44056.XP_009034721.1	4.48e-10	74.0	KOG2156@1|root,KOG2156@2759|Eukaryota	2759|Eukaryota	S	protein polyglutamylation	ttll-15	GO:0000003,GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0007610,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018094,GO:0018193,GO:0018200,GO:0018991,GO:0019098,GO:0019538,GO:0022414,GO:0032501,GO:0032504,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0048609,GO:0070735,GO:0071704,GO:0140096,GO:1901564	6.3.2.25	ko:K06047,ko:K16601,ko:K16610,ko:K16770	-	-	-	-	ko00000,ko01000,ko03036,ko04812	-	-	-	TTL
CMS1_k127_5033736_1	1279038.KB907348_gene3100	8.777e-193	621.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2TR2B@28211|Alphaproteobacteria,2JQWU@204441|Rhodospirillales	204441|Rhodospirillales	O	COG0790 FOG TPR repeat, SEL1 subfamily	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
CMS1_k127_5033736_8	688269.Theth_1082	6.669e-94	316.0	COG1028@1|root,COG1028@2|Bacteria,2GDVT@200918|Thermotogae	200918|Thermotogae	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS1_k127_5033736_6	886293.Sinac_1624	3.35e-111	366.0	COG0546@1|root,COG0546@2|Bacteria,2IYT6@203682|Planctomycetes	203682|Planctomycetes	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
CMS1_k127_5033736_7	500640.CIT292_06165	4.76e-97	331.0	COG0111@1|root,COG0111@2|Bacteria,1N5TD@1224|Proteobacteria,1RMFW@1236|Gammaproteobacteria,3WX9T@544|Citrobacter	1236|Gammaproteobacteria	EH	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate	pdxB	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0033711,GO:0034641,GO:0036001,GO:0036094,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	1.1.1.290	ko:K03473	ko00750,ko01100,map00750,map01100	M00124	R04210	RC00084	ko00000,ko00001,ko00002,ko01000	-	-	iZ_1308.Z3582	2-Hacid_dh,2-Hacid_dh_C,DUF3410
CMS1_k127_5033736_4	756272.Plabr_2258	1.337e-157	512.0	COG3875@1|root,COG3875@2|Bacteria,2IY1E@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
CMS1_k127_5033736_14	391623.TERMP_01053	1.061e-14	77.0	COG1669@1|root,arCOG01206@2157|Archaea	2157|Archaea	M	PFAM DNA polymerase beta domain protein region	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
CMS1_k127_5033736_2	530564.Psta_2483	1.25e-192	611.0	COG0205@1|root,COG0205@2|Bacteria,2IYRQ@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
CMS1_k127_5033736_0	1499967.BAYZ01000166_gene6617	1.794e-252	786.0	COG0362@1|root,COG0362@2|Bacteria,2NS40@2323|unclassified Bacteria	2|Bacteria	G	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
CMS1_k127_5033736_9	1121091.AUMP01000003_gene2848	2.277e-84	289.0	COG1082@1|root,COG1082@2|Bacteria,1TRGF@1239|Firmicutes,4HUEM@91061|Bacilli	91061|Bacilli	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS1_k127_5033736_5	1219084.AP014508_gene184	3.439e-113	376.0	COG1052@1|root,COG1052@2|Bacteria,2GC25@200918|Thermotogae	200918|Thermotogae	C	D-isomer specific 2-hydroxyacid dehydrogenase catalytic	-	-	1.1.1.26	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	-	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
CMS1_k127_5033736_11	313628.LNTAR_08246	7.003e-64	226.0	COG3363@1|root,COG3363@2|Bacteria	2|Bacteria	F	IMP cyclohydrolase activity	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	IMP_cyclohyd
CMS1_k127_5033736_15	215803.DB30_3710	2.232e-10	65.0	COG0464@1|root,COG0464@2|Bacteria,1MW4T@1224|Proteobacteria,42MBU@68525|delta/epsilon subdivisions,2WIJP@28221|Deltaproteobacteria,2YWW6@29|Myxococcales	28221|Deltaproteobacteria	O	ATPase family associated with various cellular activities (AAA)	-	-	3.6.4.6	ko:K06027	ko04138,ko04721,ko04727,ko04962,map04138,map04721,map04727,map04962	-	-	-	ko00000,ko00001,ko01000,ko04131	1.F.1.1	-	-	AAA
CMS1_k127_5056532_3	1121121.KB894307_gene2052	1.107e-43	164.0	COG0318@1|root,COG0318@2|Bacteria,1UIZD@1239|Firmicutes,4ISY9@91061|Bacilli	91061|Bacilli	IQ	AMP-binding enzyme	-	-	6.2.1.3	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
CMS1_k127_5056532_2	1173028.ANKO01000112_gene4785	1.469e-88	302.0	COG3153@1|root,COG3153@2|Bacteria,1GQ2E@1117|Cyanobacteria,1HHZD@1150|Oscillatoriales	1117|Cyanobacteria	S	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5056532_4	861299.J421_1814	7.145e-35	145.0	COG0170@1|root,COG0170@2|Bacteria	2|Bacteria	I	dolichyl monophosphate biosynthetic process	-	-	2.7.1.182,2.7.7.41	ko:K00981,ko:K18678	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799,R10659	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1,DUF92
CMS1_k127_5056532_1	1042163.BRLA_c023900	1.818e-120	398.0	COG5379@1|root,COG5379@2|Bacteria,1V1UP@1239|Firmicutes,4HX2Z@91061|Bacilli	91061|Bacilli	I	Protein of unknown function (DUF3419)	-	-	-	ko:K13622	ko00564,map00564	-	R09072	RC00021,RC01091	ko00000,ko00001	-	-	-	DUF3419
CMS1_k127_5056532_0	1173028.ANKO01000112_gene4787	1.021e-156	510.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1GBMT@1117|Cyanobacteria,1HE9H@1150|Oscillatoriales	1117|Cyanobacteria	GT	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
CMS1_k127_5060884_1	880070.Cycma_3662	4.655e-127	417.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS1_k127_5060884_3	1142394.PSMK_05320	5.297e-70	254.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	araN	-	-	ko:K17234	ko02010,map02010	M00602	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.34	-	-	SBP_bac_1,SBP_bac_8
CMS1_k127_5060884_2	1142394.PSMK_05330	8.341e-78	271.0	COG1175@1|root,COG1175@2|Bacteria	2|Bacteria	P	transmembrane transport	araP	-	-	ko:K02025,ko:K10118,ko:K15771,ko:K17235,ko:K17245	ko02010,map02010	M00196,M00207,M00491,M00601,M00602	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.28,3.A.1.1.34,3.A.1.1.40	-	-	BPD_transp_1
CMS1_k127_5060884_4	1345697.M493_09830	4.468e-62	232.0	COG0395@1|root,COG0395@2|Bacteria,1TT5G@1239|Firmicutes,4HCVZ@91061|Bacilli,1WG45@129337|Geobacillus	91061|Bacilli	G	Binding-protein-dependent transport system inner membrane component	araQ	-	-	ko:K17236	ko02010,map02010	M00602	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.34	-	-	BPD_transp_1
CMS1_k127_5060884_5	517418.Ctha_0801	9.973e-40	150.0	COG0537@1|root,COG0537@2|Bacteria,1FE24@1090|Chlorobi	1090|Chlorobi	FG	PFAM histidine triad (HIT) protein	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
CMS1_k127_5060884_0	215803.DB30_4577	3.509e-188	603.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42MMK@68525|delta/epsilon subdivisions,2WJC1@28221|Deltaproteobacteria,2YUAB@29|Myxococcales	28221|Deltaproteobacteria	S	ABC transporter	yjjK	-	3.6.3.25	ko:K06020	-	-	-	-	ko00000,ko01000	-	-	-	ABC_tran,ABC_tran_Xtn
CMS1_k127_5060884_6	1303518.CCALI_01619	7.617e-29	128.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	AXE1,Hydrolase_4
CMS1_k127_5060884_10	247490.KSU1_C1333	8.578e-16	89.0	COG4968@1|root,COG4968@2|Bacteria,2J519@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CMS1_k127_5060884_8	247490.KSU1_C1333	6.872e-19	98.0	COG4968@1|root,COG4968@2|Bacteria,2J519@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CMS1_k127_5069974_6	1499967.BAYZ01000193_gene3903	2.949e-16	84.0	2DMC5@1|root,32IWK@2|Bacteria,2NREU@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5069974_4	468556.AQYG01000049_gene1048	4.311e-25	111.0	COG2001@1|root,COG2001@2|Bacteria,2IHUB@201174|Actinobacteria,4GDZ6@85026|Gordoniaceae	201174|Actinobacteria	K	MraZ protein, putative antitoxin-like	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0040007,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
CMS1_k127_5069974_7	880073.Calab_1891	2.998e-12	73.0	COG1366@1|root,COG1366@2|Bacteria,2NRMX@2323|unclassified Bacteria	2|Bacteria	T	STAS domain	btrV	-	-	ko:K04749,ko:K06378	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
CMS1_k127_5069974_3	428125.CLOLEP_02193	2.545e-64	233.0	COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,248B5@186801|Clostridia,3WH07@541000|Ruminococcaceae	186801|Clostridia	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
CMS1_k127_5069974_1	289376.THEYE_A1329	1.244e-96	345.0	COG0768@1|root,COG0768@2|Bacteria,3J0FH@40117|Nitrospirae	40117|Nitrospirae	M	Penicillin-binding Protein dimerisation domain	-	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
CMS1_k127_5069974_0	1120973.AQXL01000130_gene1221	5.245e-119	401.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,4H9T1@91061|Bacilli,2782R@186823|Alicyclobacillaceae	91061|Bacilli	M	acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS1_k127_5069974_2	1123288.SOV_1c09960	8.295e-83	291.0	COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,4H1XX@909932|Negativicutes	909932|Negativicutes	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS1_k127_5069974_5	1156937.MFUM_1050002	1.171e-21	97.0	COG0472@1|root,COG0472@2|Bacteria,46SD0@74201|Verrucomicrobia,37GBT@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
CMS1_k127_5073587_0	1232410.KI421428_gene1054	5.001e-107	348.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKJX@28221|Deltaproteobacteria,43S25@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Domains REC, sigma54 interaction, HTH8	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS1_k127_5073587_1	395495.Lcho_4135	2.001e-12	78.0	COG3391@1|root,COG3391@2|Bacteria,1NT97@1224|Proteobacteria,2VNUX@28216|Betaproteobacteria,1KNES@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
CMS1_k127_5075547_3	1471522.JFNU01000169_gene932	1.529e-06	50.0	COG0752@1|root,COG0752@2|Bacteria,1G097@1117|Cyanobacteria,1MKEE@1212|Prochloraceae	1117|Cyanobacteria	J	Glycyl-tRNA synthetase, alpha subunit	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2e
CMS1_k127_5075547_1	5786.XP_003293123.1	1.399e-60	226.0	COG1409@1|root,KOG1378@2759|Eukaryota,3XGP6@554915|Amoebozoa	554915|Amoebozoa	S	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Pur_ac_phosph_N
CMS1_k127_5075547_0	344747.PM8797T_01084	3.802e-129	420.0	COG1957@1|root,COG1957@2|Bacteria,2IYE3@203682|Planctomycetes	203682|Planctomycetes	F	COG1957 Inosine-uridine nucleoside N-ribohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	IU_nuc_hydro
CMS1_k127_5075547_2	1073999.BN137_1782	2.252e-07	56.0	COG0454@1|root,COG0456@2|Bacteria,1RHB3@1224|Proteobacteria,1S5VR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	ysnE	-	-	ko:K03829	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
CMS1_k127_5083250_0	671143.DAMO_2996	2.063e-127	424.0	COG1032@1|root,COG1032@2|Bacteria,2NQU0@2323|unclassified Bacteria	2|Bacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
CMS1_k127_5083250_1	378806.STAUR_6389	4.523e-06	57.0	COG1807@1|root,COG1807@2|Bacteria,1PC5B@1224|Proteobacteria,438IP@68525|delta/epsilon subdivisions,2X6BS@28221|Deltaproteobacteria,2YX2I@29|Myxococcales	28221|Deltaproteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5084187_2	797303.Natpe_1391	4.74e-65	233.0	COG0277@1|root,arCOG00337@2157|Archaea,2XT5C@28890|Euryarchaeota,23SCM@183963|Halobacteria	183963|Halobacteria	C	COG0277 FAD FMN-containing dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17,Fer4_8
CMS1_k127_5084187_3	204669.Acid345_1570	2.243e-30	126.0	COG4968@1|root,COG4968@2|Bacteria,3Y98E@57723|Acidobacteria,2JP4Y@204432|Acidobacteriia	57723|Acidobacteria	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
CMS1_k127_5084187_1	1123277.KB893174_gene5952	1.135e-151	493.0	COG3540@1|root,COG3540@2|Bacteria,4PIVI@976|Bacteroidetes,47SNE@768503|Cytophagia	976|Bacteroidetes	P	PhoD-like phosphatase	-	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD,PhoD_N
CMS1_k127_5084187_6	1033732.CAHI01000007_gene2052	5.122e-21	108.0	COG2730@1|root,COG2730@2|Bacteria,4NJTQ@976|Bacteroidetes,2FRS3@200643|Bacteroidia	976|Bacteroidetes	G	alpha-galactosidase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Melibiase
CMS1_k127_5084187_0	404589.Anae109_2424	3.505e-177	580.0	COG0249@1|root,COG0249@2|Bacteria,1N9K4@1224|Proteobacteria,42ZN5@68525|delta/epsilon subdivisions,2WUW7@28221|Deltaproteobacteria,2YTSE@29|Myxococcales	28221|Deltaproteobacteria	L	ATPase domain of DNA mismatch repair MUTS family	-	-	-	-	-	-	-	-	-	-	-	-	MutS_III,MutS_V
CMS1_k127_5084187_4	1140003.I573_00721	5.991e-25	120.0	COG1388@1|root,COG1705@1|root,COG1388@2|Bacteria,COG1705@2|Bacteria,1UYRM@1239|Firmicutes,4HAU6@91061|Bacilli,4AZE2@81852|Enterococcaceae	91061|Bacilli	MNU	defense response to other organism	acmA	GO:0005575,GO:0005576	-	ko:K02395,ko:K19220,ko:K19223	-	-	-	-	ko00000,ko01000,ko01002,ko01011,ko02035	-	CBM50	-	Glucosaminidase,LysM
CMS1_k127_5084187_5	1121346.KB899816_gene3252	1.424e-24	119.0	COG1472@1|root,COG1472@2|Bacteria,1TP63@1239|Firmicutes,4HBDB@91061|Bacilli,26RMX@186822|Paenibacillaceae	91061|Bacilli	G	Glycoside hydrolase family 3	nagZ	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4309,Glyco_hydro_3
CMS1_k127_5085950_8	555779.Dthio_PD1962	1.1e-19	92.0	COG2827@1|root,COG2827@2|Bacteria	2|Bacteria	L	Endonuclease containing a URI domain	yazA	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
CMS1_k127_5085950_0	1235811.HMPREF0653_01697	8.22e-114	378.0	COG0045@1|root,COG0045@2|Bacteria,4NFHA@976|Bacteroidetes,2FNFG@200643|Bacteroidia	976|Bacteroidetes	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
CMS1_k127_5085950_1	1129374.AJE_16834	4.344e-113	371.0	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,1RM7Y@1236|Gammaproteobacteria,4652M@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009361,GO:0009987,GO:0016310,GO:0019538,GO:0032991,GO:0036211,GO:0042709,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0046777,GO:0071704,GO:1901564,GO:1902494	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	iE2348C_1286.E2348C_0608	CoA_binding,Ligase_CoA
CMS1_k127_5085950_7	7668.SPU_006327-tr	2.72e-20	98.0	COG0666@1|root,KOG4177@2759|Eukaryota,38BVK@33154|Opisthokonta,3BS9Y@33208|Metazoa	33208|Metazoa	M	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_4,Ank_5
CMS1_k127_5085950_5	398767.Glov_3374	5.904e-52	201.0	COG0457@1|root,COG0463@1|root,COG1216@1|root,COG0457@2|Bacteria,COG0463@2|Bacteria,COG1216@2|Bacteria,1P77I@1224|Proteobacteria,42TJP@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_23,TPR_16,TPR_8
CMS1_k127_5085950_6	1123508.JH636443_gene4985	9.549e-49	176.0	COG0640@1|root,COG0640@2|Bacteria,2J0I4@203682|Planctomycetes	203682|Planctomycetes	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
CMS1_k127_5085950_3	1210884.HG799471_gene14625	1.576e-66	229.0	COG3832@1|root,COG3832@2|Bacteria,2J16I@203682|Planctomycetes	203682|Planctomycetes	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
CMS1_k127_5085950_4	1123508.JH636443_gene4618	1.756e-59	214.0	COG3832@1|root,COG3832@2|Bacteria,2J08M@203682|Planctomycetes	203682|Planctomycetes	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
CMS1_k127_5085950_2	796606.BMMGA3_09755	1.902e-67	234.0	COG3832@1|root,COG3832@2|Bacteria,1V352@1239|Firmicutes,4HIVF@91061|Bacilli,1ZDWI@1386|Bacillus	91061|Bacilli	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
CMS1_k127_5096718_1	1218084.BBJK01000029_gene2794	2.864e-221	702.0	COG3408@1|root,COG3408@2|Bacteria,1MW01@1224|Proteobacteria,2W0E8@28216|Betaproteobacteria,1K24K@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Glycogen debranching enzyme N terminal	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N
CMS1_k127_5096718_13	1536770.R50345_13680	5.923e-37	144.0	COG0454@1|root,COG0456@2|Bacteria,1V86G@1239|Firmicutes,4HJIA@91061|Bacilli,26XJW@186822|Paenibacillaceae	91061|Bacilli	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
CMS1_k127_5096718_11	479437.Elen_2287	4.699e-43	173.0	28HHD@1|root,2Z7T3@2|Bacteria,2HUIJ@201174|Actinobacteria,4CUU6@84998|Coriobacteriia	84998|Coriobacteriia	S	Protein of unknown function (DUF3810)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3810
CMS1_k127_5096718_5	1408422.JHYF01000001_gene2887	1.348e-122	408.0	COG2204@1|root,COG2204@2|Bacteria,1VSKG@1239|Firmicutes,24ZP4@186801|Clostridia,36EVK@31979|Clostridiaceae	186801|Clostridia	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS1_k127_5096718_20	264201.pc1166	7.882e-14	76.0	2AKRI@1|root,31BID@2|Bacteria,2JGD9@204428|Chlamydiae	204428|Chlamydiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5096718_14	1499967.BAYZ01000118_gene3298	3.067e-26	111.0	COG2835@1|root,COG2835@2|Bacteria	2|Bacteria	EG	tetraacyldisaccharide 4'-kinase activity	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Methyltransf_25,Trm112p
CMS1_k127_5096718_12	237368.SCABRO_02154	1.752e-37	149.0	COG0811@1|root,COG0811@2|Bacteria,2IZ3U@203682|Planctomycetes	203682|Planctomycetes	U	MotA TolQ ExbB proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
CMS1_k127_5096718_28	1207063.P24_11175	0.000238	52.0	COG0810@1|root,COG0810@2|Bacteria,1MZXC@1224|Proteobacteria,2UCBT@28211|Alphaproteobacteria,2JTP2@204441|Rhodospirillales	204441|Rhodospirillales	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
CMS1_k127_5096718_25	1157490.EL26_05620	1.625e-06	61.0	2ACIQ@1|root,3124W@2|Bacteria,1V104@1239|Firmicutes,4HFYB@91061|Bacilli,277Z3@186823|Alicyclobacillaceae	91061|Bacilli	S	Helicase conserved C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C_3
CMS1_k127_5096718_22	1313304.CALK_2224	8.509e-09	67.0	COG5581@1|root,COG5581@2|Bacteria	2|Bacteria	M	regulation of bacterial-type flagellum-dependent cell motility by regulation of motor speed	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
CMS1_k127_5096718_26	279238.Saro_2650	3.972e-05	53.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,2U8VA@28211|Alphaproteobacteria,2K4TG@204457|Sphingomonadales	204457|Sphingomonadales	NU	general secretion pathway protein G	gspG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
CMS1_k127_5096718_9	1487923.DP73_14950	1.194e-72	265.0	COG3875@1|root,COG3875@2|Bacteria,1TQ1C@1239|Firmicutes,247PH@186801|Clostridia,261WJ@186807|Peptococcaceae	186801|Clostridia	S	conserved protein (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
CMS1_k127_5096718_7	863365.XHC_0224	1.14e-78	287.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1X59D@135614|Xanthomonadales	135614|Xanthomonadales	T	Sigma-54 interaction domain	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS1_k127_5096718_19	861299.J421_3275	2.317e-15	84.0	COG1399@1|root,COG1399@2|Bacteria,1ZTSW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
CMS1_k127_5096718_18	1123267.JONN01000001_gene2419	5.12e-16	79.0	COG0333@1|root,COG0333@2|Bacteria,1PU3Y@1224|Proteobacteria,2UF54@28211|Alphaproteobacteria,2K6RY@204457|Sphingomonadales	204457|Sphingomonadales	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
CMS1_k127_5096718_6	768670.Calni_1222	1.401e-90	310.0	COG0416@1|root,COG0416@2|Bacteria,2GEZX@200930|Deferribacteres	200930|Deferribacteres	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
CMS1_k127_5096718_8	1200557.JHWV01000001_gene418	2.841e-75	261.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,4H2JC@909932|Negativicutes	909932|Negativicutes	IQ	reductase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS1_k127_5096718_24	797303.Natpe_3498	1.284e-07	65.0	COG1670@1|root,arCOG00842@2157|Archaea,2XVC6@28890|Euryarchaeota,23TBU@183963|Halobacteria	183963|Halobacteria	J	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
CMS1_k127_5096718_15	1121468.AUBR01000022_gene2819	1.317e-21	111.0	COG0641@1|root,COG0641@2|Bacteria,1TQPS@1239|Firmicutes,248DD@186801|Clostridia,42ENT@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM Radical SAM domain protein	scfB	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
CMS1_k127_5096718_23	321327.CYA_1761	3.378e-08	64.0	COG1511@1|root,COG1511@2|Bacteria,1G2V0@1117|Cyanobacteria,1H06M@1129|Synechococcus	1117|Cyanobacteria	S	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
CMS1_k127_5096718_10	105422.BBPM01000105_gene4297	1.373e-69	248.0	COG1131@1|root,COG1131@2|Bacteria,2GTNE@201174|Actinobacteria,2NJ3E@228398|Streptacidiphilus	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_5096718_17	1230342.CTM_20866	3.731e-18	94.0	COG1670@1|root,COG1670@2|Bacteria,1V1G8@1239|Firmicutes,24G73@186801|Clostridia,36HY5@31979|Clostridiaceae	186801|Clostridia	J	GNAT family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
CMS1_k127_5096718_21	1449049.JONW01000009_gene4407	3.812e-12	74.0	COG1670@1|root,COG1670@2|Bacteria,1N1AB@1224|Proteobacteria,2UB2R@28211|Alphaproteobacteria,2KGVD@204458|Caulobacterales	204458|Caulobacterales	J	TIGRFAM pseudaminic acid biosynthesis N-acetyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
CMS1_k127_5096718_27	1120934.KB894414_gene3709	0.000105	52.0	COG1670@1|root,COG1670@2|Bacteria,2HNQA@201174|Actinobacteria,4E74E@85010|Pseudonocardiales	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
CMS1_k127_5096718_2	1303518.CCALI_02688	4.141e-201	637.0	COG0493@1|root,COG0493@2|Bacteria	2|Bacteria	C	'glutamate synthase	gltD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	iJN678.gltD,iNJ661.Rv3858c,iSB619.SA_RS02450	Fer4_20,Pyr_redox_2
CMS1_k127_5096718_0	525904.Tter_0474	0.0	1861.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,2NP08@2323|unclassified Bacteria	2|Bacteria	E	Glutamate synthase central domain	gltB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016020,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
CMS1_k127_5096718_3	383372.Rcas_3812	1.773e-146	469.0	COG0462@1|root,COG0462@2|Bacteria,2G5T8@200795|Chloroflexi,376D2@32061|Chloroflexia	32061|Chloroflexia	F	Phosphoribosyl synthetase-associated domain	-	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
CMS1_k127_5096718_4	1353531.AZNX01000005_gene3327	8.24e-132	435.0	COG4287@1|root,COG4287@2|Bacteria,1NP5V@1224|Proteobacteria	1224|Proteobacteria	O	PhoPQ-activated pathogenicity-related protein	pqaA	-	-	-	-	-	-	-	-	-	-	-	PhoPQ_related
CMS1_k127_5096718_16	234267.Acid_5504	1.944e-19	90.0	2C750@1|root,33NYP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5106849_1	977880.RALTA_A1536	5.811e-108	383.0	COG0421@1|root,COG0421@2|Bacteria,1P220@1224|Proteobacteria,2VNDM@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Spermine/spermidine synthase domain	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
CMS1_k127_5106849_0	575540.Isop_1244	9.868e-127	415.0	COG3622@1|root,COG3622@2|Bacteria,2IYNY@203682|Planctomycetes	203682|Planctomycetes	G	Xylose isomerase-like TIM barrel	-	-	5.3.1.22	ko:K01816	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
CMS1_k127_5128335_0	1173027.Mic7113_0690	2.329e-27	121.0	COG3393@1|root,COG3393@2|Bacteria,1G551@1117|Cyanobacteria,1HESK@1150|Oscillatoriales	1117|Cyanobacteria	S	FR47-like protein	-	-	-	ko:K06976	-	-	-	-	ko00000	-	-	-	Acetyltransf_1,FR47
CMS1_k127_5144108_8	203122.Sde_2859	7.711e-30	127.0	2E3PH@1|root,32YMK@2|Bacteria,1NVHV@1224|Proteobacteria,1SN9W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5144108_2	1121468.AUBR01000014_gene2225	1.072e-110	368.0	COG0547@1|root,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,247WY@186801|Clostridia,42EK5@68295|Thermoanaerobacterales	186801|Clostridia	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
CMS1_k127_5144108_4	926561.KB900620_gene2994	2.477e-73	256.0	COG0134@1|root,COG0134@2|Bacteria,1TR94@1239|Firmicutes,249ZY@186801|Clostridia,3WBPX@53433|Halanaerobiales	186801|Clostridia	E	Belongs to the TrpC family	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
CMS1_k127_5144108_6	243231.GSU2378	7.097e-55	199.0	COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,42QQ3@68525|delta/epsilon subdivisions,2WNPH@28221|Deltaproteobacteria,43U0C@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
CMS1_k127_5144108_0	671143.DAMO_1414	3.046e-179	571.0	COG0133@1|root,COG0133@2|Bacteria,2NNWF@2323|unclassified Bacteria	2|Bacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS1_k127_5144108_3	1123070.KB899266_gene2515	3.872e-76	263.0	COG0159@1|root,COG0159@2|Bacteria,46SK1@74201|Verrucomicrobia,2ITJI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
CMS1_k127_5144108_5	330214.NIDE4102	1.241e-62	226.0	COG1989@1|root,COG1989@2|Bacteria,3J0SK@40117|Nitrospirae	40117|Nitrospirae	NOU	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	-	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
CMS1_k127_5144108_1	635013.TherJR_1742	5.067e-126	414.0	COG0082@1|root,COG0082@2|Bacteria,1TQ40@1239|Firmicutes,24998@186801|Clostridia,260PN@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
CMS1_k127_5144108_7	279010.BL00810	2.389e-54	205.0	COG0491@1|root,COG0491@2|Bacteria,1TQPX@1239|Firmicutes,4HAV6@91061|Bacilli,1ZCFS@1386|Bacillus	91061|Bacilli	S	COG0491 Zn-dependent hydrolases, including glyoxylases	yqjP	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS1_k127_5151579_0	373903.Hore_13580	1.106e-107	364.0	COG1032@1|root,COG1032@2|Bacteria,1TPGT@1239|Firmicutes,247JS@186801|Clostridia,3WC51@53433|Halanaerobiales	186801|Clostridia	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4080,Radical_SAM
CMS1_k127_5151579_1	357276.EL88_18955	8.397e-26	112.0	2DHZ4@1|root,301FF@2|Bacteria,4PBGQ@976|Bacteroidetes,2FZ1N@200643|Bacteroidia,4AUBT@815|Bacteroidaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5165090_2	1051632.TPY_3590	1.865e-146	486.0	COG0247@1|root,COG0479@1|root,COG2181@1|root,COG0247@2|Bacteria,COG0479@2|Bacteria,COG2181@2|Bacteria,1TPG1@1239|Firmicutes,24BBE@186801|Clostridia	186801|Clostridia	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
CMS1_k127_5165090_6	1121430.JMLG01000001_gene2205	3.156e-77	269.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,260BA@186807|Peptococcaceae	186801|Clostridia	C	electron transfer flavoprotein, alpha subunit	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha,Fer4
CMS1_k127_5165090_8	765869.BDW_00090	7.536e-47	178.0	COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,42RCI@68525|delta/epsilon subdivisions,2MSVB@213481|Bdellovibrionales,2WMYC@28221|Deltaproteobacteria	213481|Bdellovibrionales	C	Electron transfer flavoprotein	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
CMS1_k127_5165090_5	1169161.KB897740_gene2297	2.206e-103	351.0	COG1960@1|root,COG1960@2|Bacteria,2GKVN@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
CMS1_k127_5165090_3	1137269.AZWL01000001_gene5345	1.175e-116	384.0	COG0346@1|root,COG0346@2|Bacteria,2I9RU@201174|Actinobacteria	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_4
CMS1_k127_5165090_4	1394178.AWOO02000006_gene3290	7.389e-105	346.0	COG1024@1|root,COG1024@2|Bacteria,2GJW5@201174|Actinobacteria,4EH13@85012|Streptosporangiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
CMS1_k127_5165090_1	1169161.KB897740_gene2294	7.982e-188	595.0	COG1960@1|root,COG1960@2|Bacteria,2GM1Q@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS1_k127_5165090_0	1169161.KB897740_gene2293	1.699e-203	649.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
CMS1_k127_5165090_9	1235279.C772_01994	4.761e-22	106.0	COG4977@1|root,COG4977@2|Bacteria,1TR2B@1239|Firmicutes,4HDMB@91061|Bacilli,26EFF@186818|Planococcaceae	91061|Bacilli	K	helix_turn_helix, arabinose operon control protein	yfiF5	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
CMS1_k127_5165090_7	344747.PM8797T_09014	4.007e-48	181.0	COG1595@1|root,COG1595@2|Bacteria,2IZH8@203682|Planctomycetes	203682|Planctomycetes	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Abhydrolase_2
CMS1_k127_5167068_2	234267.Acid_4210	6.286e-109	366.0	COG3669@1|root,COG3669@2|Bacteria,3Y43P@57723|Acidobacteria	57723|Acidobacteria	G	PFAM glycoside hydrolase, family 29	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos
CMS1_k127_5167068_3	1396418.BATQ01000011_gene4504	4.909e-86	301.0	COG0673@1|root,COG0673@2|Bacteria,46UYM@74201|Verrucomicrobia,2IVG2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_5167068_1	1449063.JMLS01000001_gene4315	9.556e-126	420.0	COG3119@1|root,COG3119@2|Bacteria,1TSHE@1239|Firmicutes,4IQVE@91061|Bacilli,276J4@186822|Paenibacillaceae	91061|Bacilli	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CMS1_k127_5167068_4	595460.RRSWK_04460	5.107e-63	226.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
CMS1_k127_5167068_0	886293.Sinac_0191	1.197e-181	582.0	COG3356@1|root,COG3356@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5167068_5	1123278.KB893427_gene1235	8.224e-41	164.0	2AQ5P@1|root,31FB4@2|Bacteria,4NRIU@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5178360_2	1229276.DI53_0943	1.617e-31	127.0	COG0744@1|root,COG0744@2|Bacteria,4NF90@976|Bacteroidetes,1IRZ0@117747|Sphingobacteriia	976|Bacteroidetes	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
CMS1_k127_5178360_0	765420.OSCT_1417	1.199e-57	224.0	COG1470@1|root,COG2385@1|root,COG1470@2|Bacteria,COG2385@2|Bacteria,2GBNA@200795|Chloroflexi,37831@32061|Chloroflexia	32061|Chloroflexia	D	Ami_2	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,PA14
CMS1_k127_5178360_3	1121456.ATVA01000016_gene2029	2.552e-08	64.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,42M2I@68525|delta/epsilon subdivisions,2WNPT@28221|Deltaproteobacteria,2MBCB@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
CMS1_k127_5178360_1	861299.J421_3045	1.293e-46	189.0	COG0515@1|root,COG0515@2|Bacteria,1ZUBQ@142182|Gemmatimonadetes	861299.J421_3045|-	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
CMS1_k127_5185100_0	2754.EH55_04400	5.122e-139	452.0	COG0043@1|root,COG0043@2|Bacteria,3T9U4@508458|Synergistetes	508458|Synergistetes	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5185100_1	1499967.BAYZ01000089_gene5015	2.81e-80	275.0	COG1212@1|root,COG1212@2|Bacteria,2NP8R@2323|unclassified Bacteria	2|Bacteria	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
CMS1_k127_5185100_2	717231.Flexsi_0368	8.247e-06	51.0	COG0457@1|root,COG0457@2|Bacteria	717231.Flexsi_0368|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5185100_3	583355.Caka_2546	0.0001484	47.0	COG0457@1|root,COG0457@2|Bacteria,46TCV@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
CMS1_k127_5189255_0	391165.GbCGDNIH1_0515	5.332e-128	432.0	COG4262@1|root,COG4262@2|Bacteria,1QUPY@1224|Proteobacteria,2TYBU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5189255_1	391165.GbCGDNIH1_0514	4.272e-98	329.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,2TVCY@28211|Alphaproteobacteria,2JRV7@204441|Rhodospirillales	204441|Rhodospirillales	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
CMS1_k127_5189255_3	1269813.ATUL01000001_gene1175	1.162e-53	195.0	COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,1S3VN@1236|Gammaproteobacteria,1WY0E@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
CMS1_k127_5189255_4	1120972.AUMH01000009_gene536	5.042e-49	190.0	COG1082@1|root,COG1082@2|Bacteria,1VBV1@1239|Firmicutes,4IRQG@91061|Bacilli	91061|Bacilli	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS1_k127_5189255_2	1461693.ATO10_04977	1.707e-55	203.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,2TSTH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
CMS1_k127_5190194_1	1411123.JQNH01000001_gene743	7.58e-20	90.0	COG0074@1|root,COG0074@2|Bacteria,1MWWN@1224|Proteobacteria,2TTYT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	CoA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding,Ligase_CoA
CMS1_k127_5190194_0	637910.ROD_p2251	9.424e-29	128.0	2AKRW@1|root,31BIT@2|Bacteria,1RK6Q@1224|Proteobacteria,1S7DH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5190194_2	1411123.JQNH01000001_gene744	1.51e-19	88.0	COG0549@1|root,COG0549@2|Bacteria,1MWXC@1224|Proteobacteria,2TVMD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the carbamate kinase family	arcC	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
CMS1_k127_520221_0	316067.Geob_0699	1.274e-151	499.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,42N2S@68525|delta/epsilon subdivisions,2WJ0E@28221|Deltaproteobacteria,43U19@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
CMS1_k127_520221_1	203119.Cthe_0896	1.047e-94	332.0	COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,2480W@186801|Clostridia,3WGFW@541000|Ruminococcaceae	186801|Clostridia	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
CMS1_k127_520221_3	383372.Rcas_1386	1.382e-30	134.0	COG0371@1|root,COG0371@2|Bacteria,2G95F@200795|Chloroflexi	200795|Chloroflexi	C	Iron-containing alcohol dehydrogenase	-	-	1.1.1.261	ko:K00096	ko00564,map00564	-	R05679,R05680	RC00029	ko00000,ko00001,ko01000	-	-	-	Fe-ADH_2
CMS1_k127_520221_2	316274.Haur_1713	1.403e-87	296.0	COG2070@1|root,COG2070@2|Bacteria,2G78C@200795|Chloroflexi,376A6@32061|Chloroflexia	32061|Chloroflexia	S	Nitronate monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
CMS1_k127_5215990_1	187272.Mlg_2038	5.233e-271	845.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RMQQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	acetolactate synthase	ilvI	GO:0000287,GO:0003674,GO:0003824,GO:0003984,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0019842,GO:0030976,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901681	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_1907,iB21_1397.B21_00078,iBWG_1329.BWG_0073,iECBD_1354.ECBD_3539,iECB_1328.ECB_00079,iECD_1391.ECD_00079,iUTI89_1310.UTI89_C0085,iYL1228.KPN_00082	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS1_k127_5215990_2	671143.DAMO_1370	5.238e-183	595.0	COG0539@1|root,COG1185@1|root,COG0539@2|Bacteria,COG1185@2|Bacteria,2NNTP@2323|unclassified Bacteria	2|Bacteria	J	Ribosomal protein S1	rpsA	-	1.17.7.4	ko:K02945,ko:K03527,ko:K07571	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	S1
CMS1_k127_5215990_3	697281.Mahau_1300	8.184e-140	464.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,42EXP@68295|Thermoanaerobacterales	186801|Clostridia	V	ABC transporter, transmembrane region	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS1_k127_5215990_4	1121129.KB903359_gene1327	3.674e-48	179.0	COG1670@1|root,COG1670@2|Bacteria,4NQB5@976|Bacteroidetes,2FTXH@200643|Bacteroidia,22Y31@171551|Porphyromonadaceae	976|Bacteroidetes	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
CMS1_k127_5215990_0	264732.Moth_0081	3.107e-272	874.0	COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,248D8@186801|Clostridia,42EQJ@68295|Thermoanaerobacterales	186801|Clostridia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
CMS1_k127_5226989_0	1442599.JAAN01000072_gene825	1.937e-07	58.0	COG1876@1|root,COG3409@1|root,COG1876@2|Bacteria,COG3409@2|Bacteria,1NAYN@1224|Proteobacteria,1SYR5@1236|Gammaproteobacteria,1XCSN@135614|Xanthomonadales	135614|Xanthomonadales	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	ko:K17733	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M15_4
CMS1_k127_5244513_0	754477.Q7C_6	4.09e-68	236.0	COG1704@1|root,COG1704@2|Bacteria,1R9YG@1224|Proteobacteria,1T06D@1236|Gammaproteobacteria,460MN@72273|Thiotrichales	72273|Thiotrichales	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
CMS1_k127_5244513_1	243233.MCA2799	5.391e-54	203.0	COG1704@1|root,COG1704@2|Bacteria,1RDUH@1224|Proteobacteria,1S2KR@1236|Gammaproteobacteria,1XGE8@135618|Methylococcales	135618|Methylococcales	S	E3 Ubiquitin ligase	-	-	-	-	-	-	-	-	-	-	-	-	GIDE
CMS1_k127_5244513_2	1168065.DOK_17210	4.474e-18	85.0	COG1309@1|root,COG1309@2|Bacteria,1MWF7@1224|Proteobacteria,1RPZ6@1236|Gammaproteobacteria,1J5T9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	D	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions	slmA	GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000918,GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0007049,GO:0007346,GO:0008150,GO:0009295,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010564,GO:0010948,GO:0010974,GO:0016043,GO:0019219,GO:0019222,GO:0022402,GO:0022607,GO:0031323,GO:0031326,GO:0031333,GO:0032271,GO:0032272,GO:0032465,GO:0032466,GO:0032506,GO:0032954,GO:0032955,GO:0042802,GO:0043085,GO:0043087,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043254,GO:0043547,GO:0043565,GO:0043590,GO:0044085,GO:0044087,GO:0044093,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0045786,GO:0045930,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051252,GO:0051301,GO:0051302,GO:0051336,GO:0051345,GO:0051726,GO:0051782,GO:0060255,GO:0061640,GO:0065007,GO:0065009,GO:0071840,GO:0080090,GO:0090529,GO:0097159,GO:0140110,GO:1901363,GO:1901891,GO:1901892,GO:1902410,GO:1902412,GO:1902413,GO:1903047,GO:1903436,GO:1903437,GO:1903506,GO:1990837,GO:2000112,GO:2001141	-	ko:K05501	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	TetR_N
CMS1_k127_5254689_2	1122132.AQYH01000006_gene3607	6.427e-67	241.0	COG3964@1|root,COG3964@2|Bacteria,1MVC7@1224|Proteobacteria,2TSUD@28211|Alphaproteobacteria,4BBMF@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Dihydroorotase	MA20_40145	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
CMS1_k127_5254689_1	1207063.P24_15269	4.904e-93	319.0	COG0596@1|root,COG0596@2|Bacteria,1MUVB@1224|Proteobacteria,2TREP@28211|Alphaproteobacteria,2JPSQ@204441|Rhodospirillales	204441|Rhodospirillales	S	Alpha/beta hydrolase family	-	-	3.8.1.3	ko:K01561	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
CMS1_k127_5254689_5	555793.WSK_2874	3.607e-15	81.0	2C42J@1|root,336T0@2|Bacteria,1NFNW@1224|Proteobacteria,2UHWX@28211|Alphaproteobacteria,2KBI7@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5254689_3	136993.KB900627_gene392	5.988e-31	132.0	28MSC@1|root,2ZB0S@2|Bacteria,1R8PG@1224|Proteobacteria,2VG09@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5254689_0	234267.Acid_7514	2.332e-133	432.0	COG3696@1|root,COG3696@2|Bacteria,3Y3AQ@57723|Acidobacteria	57723|Acidobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787,ko:K15726	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.2,2.A.6.1.4	-	-	ACR_tran
CMS1_k127_526148_20	497964.CfE428DRAFT_6508	7.288e-23	105.0	COG1309@1|root,COG1309@2|Bacteria,46WN2@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS1_k127_526148_16	587753.EY04_12215	6.983e-40	157.0	COG2020@1|root,COG2020@2|Bacteria,1R7G6@1224|Proteobacteria,1S9RT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Isoprenylcysteine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
CMS1_k127_526148_7	335543.Sfum_2526	7.158e-95	321.0	COG1163@1|root,COG1163@2|Bacteria,1RFPD@1224|Proteobacteria,42ZF3@68525|delta/epsilon subdivisions,2WUZY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TGS domain	-	-	-	ko:K06944	-	-	-	-	ko00000	-	-	-	MMR_HSR1,TGS
CMS1_k127_526148_12	1125863.JAFN01000001_gene3407	1.275e-71	249.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,42QNS@68525|delta/epsilon subdivisions,2WMSN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
CMS1_k127_526148_10	443144.GM21_3423	1.715e-82	290.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,42MV0@68525|delta/epsilon subdivisions,2WITK@28221|Deltaproteobacteria,43T9B@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
CMS1_k127_526148_0	246194.CHY_2365	8.901e-171	550.0	COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,247VX@186801|Clostridia,42EMJ@68295|Thermoanaerobacterales	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon,tRNA_bind
CMS1_k127_526148_4	644966.Tmar_0202	1.205e-116	386.0	COG1186@1|root,COG1186@2|Bacteria,1TPSB@1239|Firmicutes,247KU@186801|Clostridia,3WCE1@538999|Clostridiales incertae sedis	186801|Clostridia	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
CMS1_k127_526148_17	1499967.BAYZ01000078_gene990	5.44e-38	153.0	COG4589@1|root,COG4589@2|Bacteria,2NPVB@2323|unclassified Bacteria	2|Bacteria	S	Belongs to the CDS family	cdsA	GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS06255	CTP_transf_1
CMS1_k127_526148_11	246194.CHY_1781	3.493e-77	267.0	COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,247TE@186801|Clostridia,42F7X@68295|Thermoanaerobacterales	186801|Clostridia	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
CMS1_k127_526148_14	1125863.JAFN01000001_gene967	6.434e-53	192.0	COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,42NAA@68525|delta/epsilon subdivisions,2WNMN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
CMS1_k127_526148_8	648996.Theam_0089	1.939e-89	301.0	COG0528@1|root,COG0528@2|Bacteria,2G3IX@200783|Aquificae	200783|Aquificae	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
CMS1_k127_526148_13	269799.Gmet_1251	2.124e-71	246.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,42NNS@68525|delta/epsilon subdivisions,2WMS3@28221|Deltaproteobacteria,43U1F@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
CMS1_k127_526148_9	1121087.AUCK01000001_gene2718	3.006e-86	298.0	COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,4H9N5@91061|Bacilli,1ZAYU@1386|Bacillus	91061|Bacilli	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
CMS1_k127_526148_2	926550.CLDAP_18850	4.3e-160	514.0	COG1448@1|root,COG1448@2|Bacteria	2|Bacteria	E	Aminotransferase	aspC	GO:0003674,GO:0003824,GO:0004069,GO:0004838,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006558,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019438,GO:0019752,GO:0019842,GO:0030170,GO:0033585,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0070279,GO:0070547,GO:0071704,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223	2.6.1.1,2.6.1.57	ko:K00813,ko:K00832	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	M00024,M00025,M00034,M00040	R00355,R00694,R00734,R00896,R01731,R02433,R02619,R05052,R07396,R10845	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iPC815.YPO1410,iSFxv_1172.SFxv_1000	Aminotran_1_2
CMS1_k127_526148_19	15368.BRADI4G40380.1	1.154e-29	123.0	COG2138@1|root,2RXIW@2759|Eukaryota,37TYY@33090|Viridiplantae,3GHWI@35493|Streptophyta,3KUS0@4447|Liliopsida,3IBDW@38820|Poales	35493|Streptophyta	S	CbiX	-	GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009058,GO:0009507,GO:0009536,GO:0009987,GO:0016829,GO:0018130,GO:0019354,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0042802,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046156,GO:0046483,GO:0048037,GO:0050896,GO:0051186,GO:0051188,GO:0051266,GO:0051536,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.4	ko:K03794	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R02864	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	CbiX
CMS1_k127_526148_1	1121396.KB893067_gene1561	3.223e-168	545.0	COG0277@1|root,COG0277@2|Bacteria,1MY08@1224|Proteobacteria,42Q28@68525|delta/epsilon subdivisions,2WMZ9@28221|Deltaproteobacteria,2MPEE@213118|Desulfobacterales	28221|Deltaproteobacteria	C	FAD binding domain	pcmI	-	1.17.99.1	ko:K05797	ko00623,ko01100,ko01120,map00623,map01100,map01120	-	R02675,R11194	RC00769	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
CMS1_k127_526148_18	756067.MicvaDRAFT_2544	5.179e-30	130.0	COG1225@1|root,COG1225@2|Bacteria,1G59X@1117|Cyanobacteria,1HAY7@1150|Oscillatoriales	1117|Cyanobacteria	O	Alkyl hydroperoxide reductase	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
CMS1_k127_526148_5	313628.LNTAR_05614	3.493e-116	390.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS1_k127_526148_3	1210884.HG799468_gene13605	1.173e-147	486.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1,Polysacc_deac_1,Polysacc_deac_3
CMS1_k127_526148_6	595460.RRSWK_03845	6.695e-103	372.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
CMS1_k127_526148_21	1142394.PSMK_15550	5.409e-14	81.0	COG2839@1|root,COG2839@2|Bacteria,2J1KN@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF456)	-	-	-	ko:K09793	-	-	-	-	ko00000	-	-	-	DUF456
CMS1_k127_526148_15	153948.NAL212_2368	4.646e-42	158.0	COG1562@1|root,COG1562@2|Bacteria,1R4ZD@1224|Proteobacteria,2VQS1@28216|Betaproteobacteria,371ZA@32003|Nitrosomonadales	28216|Betaproteobacteria	I	PFAM Squalene phytoene synthase	fdfT	-	2.5.1.21	ko:K00801	ko00100,ko00909,ko01100,ko01110,ko01130,map00100,map00909,map01100,map01110,map01130	-	R00702,R02872,R06223	RC00362,RC00796,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	SQS_PSY
CMS1_k127_5281705_2	1354722.JQLS01000004_gene4071	6.268e-05	55.0	28JVS@1|root,2Z9KP@2|Bacteria,1R74U@1224|Proteobacteria,2U1XR@28211|Alphaproteobacteria,46RSW@74030|Roseovarius	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5281705_0	373994.Riv7116_0483	9.258e-142	464.0	COG1035@1|root,COG1035@2|Bacteria,1GIR2@1117|Cyanobacteria,1HS09@1161|Nostocales	1117|Cyanobacteria	C	Coenzyme F420 hydrogenase dehydrogenase, beta subunit C terminus	-	-	-	-	-	-	-	-	-	-	-	-	FrhB_FdhB_C,FrhB_FdhB_N
CMS1_k127_5281705_1	313628.LNTAR_11821	5.16e-43	171.0	COG2244@1|root,COG2244@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
CMS1_k127_5293486_1	1267535.KB906767_gene5001	5.281e-53	211.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,Sulfatase
CMS1_k127_5293486_0	1267533.KB906737_gene1677	2.108e-130	453.0	COG0457@1|root,COG0457@2|Bacteria,3Y4J2@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF5107)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5107
CMS1_k127_5293486_2	1329516.JPST01000018_gene2643	4.778e-38	158.0	COG2369@1|root,COG2369@2|Bacteria	2|Bacteria	K	cell adhesion	-	-	-	-	-	-	-	-	-	-	-	-	Phage_Mu_F,Phage_min_cap2
CMS1_k127_5293486_3	1232443.BAIA02000141_gene1674	7.895e-18	90.0	28MWX@1|root,2ZB45@2|Bacteria,1UZ34@1239|Firmicutes,24EV8@186801|Clostridia,268WI@186813|unclassified Clostridiales	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5313287_1	768671.ThimaDRAFT_4351	2.268e-15	81.0	2CM51@1|root,32ZGG@2|Bacteria,1NG5E@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5313287_2	658655.HMPREF0988_02859	4.019e-14	85.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1URF2@1239|Firmicutes,25BRU@186801|Clostridia,27TZH@186928|unclassified Lachnospiraceae	186801|Clostridia	T	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC,Response_reg
CMS1_k127_5313287_0	502025.Hoch_4759	2.706e-102	349.0	COG2271@1|root,COG2271@2|Bacteria,1MVV4@1224|Proteobacteria,435CH@68525|delta/epsilon subdivisions,2WZQ3@28221|Deltaproteobacteria,2Z2HU@29|Myxococcales	28221|Deltaproteobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_5313287_4	926566.Terro_2869	5.122e-06	53.0	COG3682@1|root,COG3682@2|Bacteria,3Y5AK@57723|Acidobacteria,2JNBY@204432|Acidobacteriia	204432|Acidobacteriia	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
CMS1_k127_5313287_5	1210884.HG799463_gene10324	7.577e-05	56.0	COG0457@1|root,COG0457@2|Bacteria,2IZWD@203682|Planctomycetes	203682|Planctomycetes	KLT	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
CMS1_k127_5313287_3	1403819.BATR01000027_gene909	4.139e-14	86.0	COG0515@1|root,COG0515@2|Bacteria,46X96@74201|Verrucomicrobia,2IV2P@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KLT	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS1_k127_5336917_2	1089548.KI783301_gene140	5.222e-57	207.0	COG1082@1|root,COG1082@2|Bacteria,1UZ90@1239|Firmicutes,4HHIS@91061|Bacilli	91061|Bacilli	G	sugar phosphate	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS1_k127_5336917_5	5786.XP_003288881.1	5.045e-08	60.0	COG0500@1|root,KOG1269@2759|Eukaryota,3XB90@554915|Amoebozoa	554915|Amoebozoa	H	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS1_k127_5336917_3	1304880.JAGB01000002_gene1979	2.188e-47	180.0	COG1082@1|root,COG1082@2|Bacteria,1UZ90@1239|Firmicutes,24DP0@186801|Clostridia	186801|Clostridia	G	TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS1_k127_5336917_0	1408473.JHXO01000009_gene3392	4.429e-135	441.0	COG4030@1|root,COG4030@2|Bacteria,4NHV9@976|Bacteroidetes,2FNZY@200643|Bacteroidia	976|Bacteroidetes	S	Protein of unknown function (DUF2961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
CMS1_k127_5336917_1	1210884.HG799464_gene11148	5.769e-73	268.0	COG2206@1|root,COG2206@2|Bacteria,2IWTK@203682|Planctomycetes	203682|Planctomycetes	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GAF_2,HD
CMS1_k127_5336917_4	1202768.JROF01000015_gene1059	3.758e-12	79.0	arCOG00567@1|root,arCOG00567@2157|Archaea,2XVU1@28890|Euryarchaeota,23UZV@183963|Halobacteria	183963|Halobacteria	M	glycosyl transferase family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS1_k127_5356543_0	118168.MC7420_5234	3.913e-65	241.0	COG5563@1|root,COG5563@2|Bacteria,1GIA8@1117|Cyanobacteria,1HFHC@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5356543_1	1298863.AUEP01000003_gene2949	4.275e-09	66.0	COG0789@1|root,COG0789@2|Bacteria,2GKAU@201174|Actinobacteria,4DQ8K@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
CMS1_k127_535981_1	1396141.BATP01000022_gene240	2.579e-87	306.0	COG0457@1|root,COG0457@2|Bacteria	1396141.BATP01000022_gene240|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_535981_0	1396141.BATP01000022_gene241	5.919e-169	547.0	2DB7W@1|root,2Z7P1@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4331)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4331
CMS1_k127_535981_3	390989.JOEG01000002_gene4287	5.041e-44	183.0	COG3387@1|root,COG3387@2|Bacteria,2IEP5@201174|Actinobacteria,4DKBN@85008|Micromonosporales	201174|Actinobacteria	G	PFAM Glycoside hydrolase 15-related	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_535981_2	1219084.AP014508_gene348	2.406e-55	201.0	COG0329@1|root,COG0329@2|Bacteria,2GDWI@200918|Thermotogae	200918|Thermotogae	E	Dihydrodipicolinate synthetase family	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
CMS1_k127_5374923_2	247633.GP2143_11944	1.656e-08	56.0	2DRA2@1|root,33AVQ@2|Bacteria,1NKZA@1224|Proteobacteria,1SH2Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5374923_0	338966.Ppro_1126	4.012e-79	277.0	COG4974@1|root,COG4974@2|Bacteria,1QV9T@1224|Proteobacteria,43CGV@68525|delta/epsilon subdivisions,2X7S1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
CMS1_k127_5387343_2	1353531.AZNX01000005_gene3327	7.706e-135	469.0	COG4287@1|root,COG4287@2|Bacteria,1NP5V@1224|Proteobacteria	1224|Proteobacteria	O	PhoPQ-activated pathogenicity-related protein	pqaA	-	-	-	-	-	-	-	-	-	-	-	PhoPQ_related
CMS1_k127_5387343_3	637905.SVI_3316	1.481e-11	79.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria,2QA62@267890|Shewanellaceae	1236|Gammaproteobacteria	MQ	Dystroglycan-type cadherin domain protein	-	-	-	ko:K11005	-	-	-	-	ko00000,ko02000,ko02042	1.C.11	-	-	Big_3_2,Cadherin_3,Calx-beta,He_PIG,HemolysinCabind,OmpA_membrane,RTX,RTX_C,VWA_2,fn3
CMS1_k127_5387343_0	357808.RoseRS_1072	2.358e-164	531.0	COG0076@1|root,COG0076@2|Bacteria,2GAD1@200795|Chloroflexi,376VF@32061|Chloroflexia	32061|Chloroflexia	E	PFAM aminotransferase class V	-	-	4.1.2.27	ko:K01634	ko00600,ko01100,ko04071,map00600,map01100,map04071	M00100	R02464,R06516	RC00264,RC00721,RC01266	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
CMS1_k127_5387343_1	509635.N824_20400	3.905e-136	445.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.4.21.96	ko:K01361,ko:K13277,ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Amidase_2,Big_2,CBM_X2,DUF1983,DUF2961,Glucosaminidase,LRR_5,Laminin_G_3,PA,Peptidase_S8,Phage-tail_3,SLH,fn3_5
CMS1_k127_5392001_0	1267533.KB906738_gene2186	9.074e-184	597.0	COG1529@1|root,COG1529@2|Bacteria,3Y3J7@57723|Acidobacteria	57723|Acidobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C2
CMS1_k127_5392001_1	525904.Tter_2354	1.234e-32	128.0	COG2080@1|root,COG2080@2|Bacteria,2NPPX@2323|unclassified Bacteria	2|Bacteria	C	PFAM 2Fe-2S -binding	iorA	-	1.2.5.3,1.3.99.16	ko:K00256,ko:K03518,ko:K07302,ko:K07303,ko:K13483	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103,R11168	RC00143,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2,Fer2_2
CMS1_k127_5396110_0	1123508.JH636439_gene821	6.987e-137	459.0	COG3391@1|root,COG3511@1|root,COG3391@2|Bacteria,COG3511@2|Bacteria,2IYNB@203682|Planctomycetes	203682|Planctomycetes	M	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase,Phosphoesterase
CMS1_k127_5396110_2	945713.IALB_1269	2.37e-53	194.0	COG1528@1|root,COG1528@2|Bacteria	2|Bacteria	P	ferric iron binding	ftnA	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
CMS1_k127_5396110_3	1246459.KB898355_gene4517	3.268e-46	174.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQMJ@28211|Alphaproteobacteria,4BAI9@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Belongs to the ABC transporter superfamily	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,TOBE_2
CMS1_k127_5396110_1	1121403.AUCV01000002_gene445	1.391e-59	227.0	COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,42TI5@68525|delta/epsilon subdivisions,2X5JQ@28221|Deltaproteobacteria,2MPF9@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
CMS1_k127_5396110_4	857087.Metme_4161	1.992e-14	75.0	COG1840@1|root,COG1840@2|Bacteria,1MXZ8@1224|Proteobacteria,1RPP5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	ABC transporter substrate-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6
CMS1_k127_5396330_1	1007096.BAGW01000017_gene799	8.513e-31	138.0	28IS3@1|root,2Z8R9@2|Bacteria,1TSHH@1239|Firmicutes,24CQ6@186801|Clostridia,2N6UG@216572|Oscillospiraceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Phage_capsid
CMS1_k127_5396330_6	1291050.JAGE01000002_gene3287	0.0004386	50.0	COG4722@1|root,COG4722@2|Bacteria,1VUQR@1239|Firmicutes	1239|Firmicutes	S	Phage tail protein	-	-	-	-	-	-	-	-	-	-	-	-	Sipho_tail
CMS1_k127_5396330_3	1047013.AQSP01000128_gene413	8.988e-14	81.0	2DU2Y@1|root,33NQT@2|Bacteria	2|Bacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_4
CMS1_k127_5396330_0	1125701.HMPREF1221_00764	9.835e-36	140.0	2DPM9@1|root,332MQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5396330_4	1123315.AUIP01000031_gene290	4.877e-12	66.0	2EG09@1|root,339SB@2|Bacteria,1VG42@1239|Firmicutes,4HRC7@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5397082_0	1267535.KB906767_gene1815	5.586e-192	623.0	COG1262@1|root,COG4409@1|root,COG1262@2|Bacteria,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2,FGE-sulfatase
CMS1_k127_5397082_2	1288963.ADIS_1080	5.811e-18	97.0	28KPG@1|root,2ZA7K@2|Bacteria,4NFWJ@976|Bacteroidetes,47MDA@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5397082_3	1480694.DC28_02705	3.656e-08	66.0	COG0664@1|root,COG4191@1|root,COG0664@2|Bacteria,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	hoxI	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	EAL,FliG_C,HATPase_c,HisKA,cNMP_binding
CMS1_k127_5397082_1	1288963.ADIS_1157	2.236e-179	576.0	COG3292@1|root,COG3292@2|Bacteria,4P1XS@976|Bacteroidetes,47U9C@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5409581_0	1079460.ATTQ01000003_gene1331	1.169e-125	413.0	COG4948@1|root,COG4948@2|Bacteria,1MURK@1224|Proteobacteria,2U0BF@28211|Alphaproteobacteria,4BBCF@82115|Rhizobiaceae	28211|Alphaproteobacteria	M	Mandelate racemase muconate	-	-	4.2.1.6	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R03033	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
CMS1_k127_5409581_1	696281.Desru_2322	7.274e-73	254.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,25ZZ5@186807|Peptococcaceae	186801|Clostridia	E	PFAM Aminotransferase class I and II	aspB	-	2.6.1.1	ko:K00812,ko:K10907	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	iHN637.CLJU_RS06550	Aminotran_1_2
CMS1_k127_5418556_2	1123242.JH636436_gene23	1.152e-128	426.0	COG1335@1|root,COG1413@1|root,COG2010@1|root,COG2133@1|root,COG3828@1|root,COG1335@2|Bacteria,COG1413@2|Bacteria,COG2010@2|Bacteria,COG2133@2|Bacteria,COG3828@2|Bacteria,2IX4V@203682|Planctomycetes	203682|Planctomycetes	C	COG2133 Glucose sorbosone dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
CMS1_k127_5418556_1	926569.ANT_30620	1.163e-136	443.0	COG1932@1|root,COG1932@2|Bacteria,2G7RM@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
CMS1_k127_5418556_4	1519464.HY22_07420	2.815e-88	301.0	COG3380@1|root,COG3380@2|Bacteria	2|Bacteria	S	monoamine oxidase activity	-	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050664,GO:0051287,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363	-	ko:K06955	-	-	-	-	ko00000	-	-	-	Amino_oxidase,NAD_binding_8
CMS1_k127_5418556_6	756272.Plabr_3042	3.52e-53	191.0	COG3476@1|root,COG3476@2|Bacteria,2J03F@203682|Planctomycetes	203682|Planctomycetes	T	PFAM TspO MBR family	-	-	-	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	-	-	-	ko00000,ko00001,ko02000	9.A.24	-	-	TspO_MBR
CMS1_k127_5418556_3	102129.Lepto7375DRAFT_2380	1.563e-88	310.0	COG3250@1|root,COG3250@2|Bacteria,1GD73@1117|Cyanobacteria	1117|Cyanobacteria	G	Horizontally Transferred TransMembrane Domain	-	-	-	-	-	-	-	-	-	-	-	-	VKG_Carbox
CMS1_k127_5418556_0	1123242.JH636434_gene3779	4.642e-256	806.0	2CCP0@1|root,2Z7XN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
CMS1_k127_5418556_5	344747.PM8797T_12348	2.652e-62	224.0	COG1028@1|root,COG1028@2|Bacteria,2IYE6@203682|Planctomycetes	203682|Planctomycetes	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.401	ko:K21883	ko00051,ko01120,map00051,map01120	-	R11339	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
CMS1_k127_542756_0	1499967.BAYZ01000032_gene1135	1.305e-117	389.0	COG4992@1|root,COG4992@2|Bacteria	2|Bacteria	E	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity	-	-	2.6.1.11,2.6.1.17,2.6.1.82	ko:K00821,ko:K09251	ko00220,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map00330,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R01155,R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CMS1_k127_542756_2	324057.Pjdr2_1145	1.578e-70	250.0	COG0667@1|root,COG0667@2|Bacteria,1TQYY@1239|Firmicutes,4HDCC@91061|Bacilli,26T55@186822|Paenibacillaceae	91061|Bacilli	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS1_k127_542756_1	452637.Oter_2237	5.714e-97	325.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	f42a	-	-	-	-	-	-	-	-	-	-	-	Band_7
CMS1_k127_542756_3	345341.KUTG_02668	1.716e-08	58.0	COG4877@1|root,COG4877@2|Bacteria,2GQV1@201174|Actinobacteria,4E6UQ@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5431340_0	1047013.AQSP01000126_gene2738	5.719e-100	338.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,HEAT_2
CMS1_k127_5431340_1	1121904.ARBP01000023_gene5048	2.675e-42	176.0	COG1409@1|root,COG1409@2|Bacteria,4NFAP@976|Bacteroidetes,47V4E@768503|Cytophagia	976|Bacteroidetes	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Fn3_assoc,Metallophos,PA14
CMS1_k127_5431340_2	1396141.BATP01000060_gene4615	5.31e-18	85.0	COG1529@1|root,COG1529@2|Bacteria,46UY9@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
CMS1_k127_5432768_4	290397.Adeh_4091	6.475e-33	139.0	2CHM7@1|root,2ZV0T@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5432768_1	1142394.PSMK_25380	3.971e-64	238.0	COG1175@1|root,COG1175@2|Bacteria	2|Bacteria	P	transmembrane transport	-	-	-	ko:K02025,ko:K10118,ko:K15771,ko:K17245	ko02010,map02010	M00196,M00207,M00491,M00601	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.28,3.A.1.1.40	-	-	BPD_transp_1
CMS1_k127_5432768_0	794903.OPIT5_09155	1.861e-84	291.0	COG0395@1|root,COG0395@2|Bacteria,46TIW@74201|Verrucomicrobia,3K8AG@414999|Opitutae	414999|Opitutae	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_5432768_2	1142394.PSMK_25370	1.933e-44	181.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
CMS1_k127_5432768_3	3641.EOY06831	3.239e-33	131.0	2BDGR@1|root,2S12K@2759|Eukaryota,37VAP@33090|Viridiplantae,3GJID@35493|Streptophyta	35493|Streptophyta	S	Probable protein Pop3	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006952,GO:0008150,GO:0009605,GO:0009607,GO:0009617,GO:0009620,GO:0016020,GO:0042742,GO:0043207,GO:0044424,GO:0044444,GO:0044464,GO:0050832,GO:0050896,GO:0051704,GO:0051707,GO:0071944,GO:0098542	-	-	-	-	-	-	-	-	-	-	Dabb
CMS1_k127_5432768_6	1047171.Mycgr3P71198	0.0009159	48.0	COG2140@1|root,2QQ0P@2759|Eukaryota,39K8V@33154|Opisthokonta,3NUDY@4751|Fungi,3QR7V@4890|Ascomycota,1ZYV8@147541|Dothideomycetes,3MJA6@451867|Dothideomycetidae	4751|Fungi	O	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_1
CMS1_k127_5432768_5	309799.DICTH_0472	1.43e-12	79.0	COG1063@1|root,COG1063@2|Bacteria	2|Bacteria	E	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_5445937_4	471870.BACINT_01039	2.045e-10	68.0	COG2382@1|root,COG2382@2|Bacteria,4NF50@976|Bacteroidetes,2G20G@200643|Bacteroidia,4ASY7@815|Bacteroidaceae	976|Bacteroidetes	P	Putative esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase
CMS1_k127_5445937_3	1403819.BATR01000069_gene2028	2.408e-22	102.0	2EGY0@1|root,33AQ5@2|Bacteria,46TXR@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5445937_0	694427.Palpr_1624	1.419e-134	441.0	COG3693@1|root,COG3693@2|Bacteria,4NE5Z@976|Bacteroidetes,2G2PS@200643|Bacteroidia,22XB8@171551|Porphyromonadaceae	976|Bacteroidetes	G	Glycosyl hydrolase family 10	-	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_10
CMS1_k127_5445937_2	694427.Palpr_1643	3.123e-122	398.0	COG2382@1|root,COG2382@2|Bacteria,4PN5S@976|Bacteroidetes,2G0RQ@200643|Bacteroidia,22YWM@171551|Porphyromonadaceae	976|Bacteroidetes	P	Pfam:DUF303	-	-	-	-	-	-	-	-	-	-	-	-	SASA
CMS1_k127_5445937_1	452637.Oter_2258	1.657e-134	431.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	ArabFuran-catal,CHU_C,DUF11,IgGFc_binding,LTD,NPCBM_assoc,Peptidase_M11,SprB
CMS1_k127_5446786_4	471857.Svir_12450	4.296e-08	65.0	COG4409@1|root,COG4409@2|Bacteria,2IHE6@201174|Actinobacteria,4EDGM@85010|Pseudonocardiales	201174|Actinobacteria	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
CMS1_k127_5446786_1	1049564.TevJSym_al00220	1.363e-138	452.0	28I6N@1|root,2Z89J@2|Bacteria,1MUVT@1224|Proteobacteria,1RQUY@1236|Gammaproteobacteria,1J7IW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5446786_2	1278309.KB907101_gene394	3.957e-104	346.0	COG2834@1|root,COG2834@2|Bacteria,1MXW0@1224|Proteobacteria,1RS0K@1236|Gammaproteobacteria,1XHXM@135619|Oceanospirillales	135619|Oceanospirillales	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
CMS1_k127_5446786_0	203122.Sde_1321	4.399e-228	730.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RPIP@1236|Gammaproteobacteria,465BT@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	exporters of the RND superfamily	VP1286	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
CMS1_k127_5446786_3	1173028.ANKO01000111_gene4995	4.974e-86	292.0	COG0318@1|root,COG0318@2|Bacteria,1G4CE@1117|Cyanobacteria,1H8QS@1150|Oscillatoriales	1117|Cyanobacteria	IQ	Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	6.1.3.1	ko:K22319	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding,AMP-binding_C,PP-binding
CMS1_k127_5448609_10	1122164.JHWF01000008_gene1246	1.205e-49	183.0	2BY1R@1|root,349MM@2|Bacteria,1P29N@1224|Proteobacteria,1ST3A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Haem-NO-binding	-	-	-	-	-	-	-	-	-	-	-	-	HNOB
CMS1_k127_5448609_8	177437.HRM2_43560	1.962e-73	258.0	COG2208@1|root,COG3437@1|root,COG2208@2|Bacteria,COG3437@2|Bacteria,1N4K5@1224|Proteobacteria,42T2F@68525|delta/epsilon subdivisions,2WPGM@28221|Deltaproteobacteria,2MKRM@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	Response_reg,SpoIIE
CMS1_k127_5448609_5	1304880.JAGB01000003_gene1139	2.253e-114	381.0	COG0673@1|root,COG0673@2|Bacteria,1TQCX@1239|Firmicutes,24EV1@186801|Clostridia	186801|Clostridia	S	Homoserine dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_5448609_1	886293.Sinac_3826	1.068e-263	834.0	COG3518@1|root,COG3518@2|Bacteria,2J26H@203682|Planctomycetes	203682|Planctomycetes	S	anti-sigma factor antagonist activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5448609_7	880070.Cycma_2941	1.197e-89	311.0	COG1914@1|root,COG1914@2|Bacteria,4NJBS@976|Bacteroidetes,47U9J@768503|Cytophagia	976|Bacteroidetes	P	Natural resistance-associated macrophage protein	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
CMS1_k127_5448609_14	1247024.JRLH01000001_gene1010	1.558e-10	63.0	2DRA2@1|root,33AVQ@2|Bacteria,1NKZA@1224|Proteobacteria,1SH2Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5448609_12	1121396.KB893120_gene3067	1.125e-19	91.0	COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria,42YNG@68525|delta/epsilon subdivisions,2WU6B@28221|Deltaproteobacteria,2MN61@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Integrase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5448609_11	1123278.KB893444_gene1666	7.723e-37	146.0	2C87P@1|root,32H7J@2|Bacteria,4NS7S@976|Bacteroidetes,47R39@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
CMS1_k127_5448609_9	296591.Bpro_0167	1.663e-52	195.0	COG4221@1|root,COG4221@2|Bacteria,1QXBX@1224|Proteobacteria,2WH93@28216|Betaproteobacteria,4AEPB@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
CMS1_k127_5448609_6	251229.Chro_3613	2.265e-91	308.0	COG0580@1|root,COG0580@2|Bacteria,1G3MJ@1117|Cyanobacteria	1117|Cyanobacteria	U	Belongs to the MIP aquaporin (TC 1.A.8) family	-	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
CMS1_k127_5448609_4	1131553.JIBI01000012_gene833	5.845e-127	411.0	COG1028@1|root,COG1028@2|Bacteria,1Q7EW@1224|Proteobacteria,2VSPV@28216|Betaproteobacteria	28216|Betaproteobacteria	IQ	KR domain	-	-	1.1.1.47	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	-	R01520,R01521	RC00066	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
CMS1_k127_5448609_0	861299.J421_5672	0.0	1349.0	COG2334@1|root,COG2334@2|Bacteria	2|Bacteria	S	homoserine kinase activity	-	-	2.7.1.39	ko:K02204	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	APH,Glyco_hydro_63
CMS1_k127_5448609_2	391038.Bphy_2402	6.218e-233	741.0	COG3408@1|root,COG3408@2|Bacteria,1MW01@1224|Proteobacteria,2W0E8@28216|Betaproteobacteria,1K24K@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Glycogen debranching enzyme N terminal	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N
CMS1_k127_5448609_3	1210884.HG799463_gene9619	5.869e-173	565.0	COG3829@1|root,COG3829@2|Bacteria	2|Bacteria	T	transcription factor binding	-	-	-	ko:K15836	-	-	-	-	ko00000,ko03000	-	-	-	GAF_2,HTH_8,PAS,PAS_4,PAS_9,Sigma54_activat
CMS1_k127_5448609_15	497964.CfE428DRAFT_5991	6.941e-05	51.0	29A7N@1|root,2ZX8K@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5460633_4	1122185.N792_02710	1.42e-07	59.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
CMS1_k127_5460633_0	1123242.JH636435_gene2024	4.535e-187	627.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXZY@203682|Planctomycetes	203682|Planctomycetes	T	COG0515 Serine threonine protein	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_10,TPR_12,TPR_8,WD40
CMS1_k127_5460633_1	1123242.JH636435_gene2023	4.698e-68	236.0	COG1595@1|root,COG1595@2|Bacteria,2IZAB@203682|Planctomycetes	203682|Planctomycetes	K	COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
CMS1_k127_5460633_2	314287.GB2207_03142	6.169e-19	96.0	COG3828@1|root,COG3828@2|Bacteria,1RHWH@1224|Proteobacteria,1T17G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
CMS1_k127_5460633_5	378806.STAUR_0328	0.0002881	54.0	COG2133@1|root,COG2133@2|Bacteria,1P3DX@1224|Proteobacteria,43894@68525|delta/epsilon subdivisions,2X3IR@28221|Deltaproteobacteria,2YW8Z@29|Myxococcales	28221|Deltaproteobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
CMS1_k127_5460633_3	1403819.BATR01000010_gene345	1.245e-07	62.0	2EZ6T@1|root,33SCS@2|Bacteria,46UHR@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5461621_0	1122925.KB895403_gene168	4.648e-108	358.0	COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,4H9YC@91061|Bacilli,26QQ5@186822|Paenibacillaceae	91061|Bacilli	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
CMS1_k127_5461621_1	373903.Hore_00890	1.834e-95	324.0	COG1623@1|root,COG1623@2|Bacteria,1TQD8@1239|Firmicutes,247J4@186801|Clostridia,3WBG7@53433|Halanaerobiales	186801|Clostridia	L	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation	disA	-	2.7.7.85	ko:K07067	-	-	-	-	ko00000,ko01000	-	-	-	DisA-linker,DisA_N,HHH,HHH_2
CMS1_k127_5461621_2	439235.Dalk_1941	1.386e-47	181.0	COG0543@1|root,COG0543@2|Bacteria,1RF43@1224|Proteobacteria,42RQK@68525|delta/epsilon subdivisions,2WNJU@28221|Deltaproteobacteria,2MKD4@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
CMS1_k127_5467029_0	937777.Deipe_1570	4.288e-52	190.0	COG0338@1|root,COG0338@2|Bacteria	2|Bacteria	L	D12 class N6 adenine-specific DNA methyltransferase	-	-	2.1.1.72	ko:K06223	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	-	-	-	MethyltransfD12,Peptidase_S78_2
CMS1_k127_5471106_0	497964.CfE428DRAFT_2146	2.359e-21	102.0	COG1262@1|root,COG1262@2|Bacteria,46VAM@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,VPEP
CMS1_k127_5471106_1	1198114.AciX9_3194	3.75e-14	79.0	COG1595@1|root,COG1595@2|Bacteria,3Y4IW@57723|Acidobacteria,2JJ89@204432|Acidobacteriia	204432|Acidobacteriia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_5475669_2	1123242.JH636435_gene2360	2.722e-140	461.0	COG1520@1|root,COG1520@2|Bacteria,2IXST@203682|Planctomycetes	203682|Planctomycetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CMS1_k127_5475669_6	1226325.HMPREF1548_02230	3.743e-45	187.0	COG3525@1|root,COG3525@2|Bacteria	2|Bacteria	G	beta-N-acetylhexosaminidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4838,F5_F8_type_C,Glyco_hydro_67N
CMS1_k127_5475669_8	1267535.KB906767_gene1715	1.501e-10	75.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	3.2.1.31	ko:K01195	ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142	M00014,M00076,M00077,M00078,M00129	R01478,R04979,R07818,R08127,R08260,R10830	RC00055,RC00171,RC00529,RC00530,RC00714,RC01251	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,fn3
CMS1_k127_5475669_4	1267535.KB906767_gene4403	6.866e-100	361.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
CMS1_k127_5475669_1	1124780.ANNU01000077_gene789	3.058e-152	497.0	COG0477@1|root,COG0477@2|Bacteria,4PKTJ@976|Bacteroidetes,47YD9@768503|Cytophagia	976|Bacteroidetes	EGP	Sugar (and other) transporter	-	-	-	ko:K08138	-	-	-	-	ko00000,ko02000	2.A.1.1.3	-	-	Sugar_tr
CMS1_k127_5475669_0	1499967.BAYZ01000009_gene5389	1.855e-167	536.0	COG0407@1|root,COG0407@2|Bacteria	2|Bacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
CMS1_k127_5475669_7	589865.DaAHT2_0150	6.736e-40	157.0	COG0655@1|root,COG0655@2|Bacteria,1RAK6@1224|Proteobacteria,42QS5@68525|delta/epsilon subdivisions,2WN2M@28221|Deltaproteobacteria,2MJW8@213118|Desulfobacterales	28221|Deltaproteobacteria	S	PFAM NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
CMS1_k127_5475669_5	1168034.FH5T_01595	5.393e-96	329.0	COG1520@1|root,COG1520@2|Bacteria,4P28I@976|Bacteroidetes,2FX0J@200643|Bacteroidia	976|Bacteroidetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
CMS1_k127_5475669_3	497964.CfE428DRAFT_4943	2.662e-136	459.0	COG0577@1|root,COG0577@2|Bacteria,46U6N@74201|Verrucomicrobia	74201|Verrucomicrobia	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
CMS1_k127_5482525_1	330214.NIDE1190	5.059e-10	63.0	COG1262@1|root,COG1262@2|Bacteria,3J14J@40117|Nitrospirae	2|Bacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
CMS1_k127_5482525_0	344747.PM8797T_18384	3.423e-57	209.0	COG0673@1|root,COG0673@2|Bacteria,2IWRC@203682|Planctomycetes	203682|Planctomycetes	S	COGs COG0673 dehydrogenase and related protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_5507228_2	90675.XP_010476662.1	6.553e-16	92.0	KOG1947@1|root,KOG1947@2759|Eukaryota,37ICC@33090|Viridiplantae,3G9ZF@35493|Streptophyta,3HRGT@3699|Brassicales	35493|Streptophyta	S	leucine-rich repeat family protein	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5,LRR_6,LRR_8
CMS1_k127_5507228_0	378806.STAUR_1714	2.422e-25	123.0	COG1196@1|root,COG4219@1|root,COG1196@2|Bacteria,COG4219@2|Bacteria,1PEGJ@1224|Proteobacteria,438JW@68525|delta/epsilon subdivisions,2X3UI@28221|Deltaproteobacteria,2YX4Y@29|Myxococcales	28221|Deltaproteobacteria	DKT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
CMS1_k127_5507228_1	366649.XFF4834R_chr00390	7.807e-23	106.0	COG3682@1|root,COG3682@2|Bacteria,1N3JW@1224|Proteobacteria,1SB84@1236|Gammaproteobacteria,1X73E@135614|Xanthomonadales	135614|Xanthomonadales	K	Methicillin resistance protein	mecI	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
CMS1_k127_5507228_3	1107311.Q767_01615	1.414e-10	68.0	COG1520@1|root,COG3291@1|root,COG3386@1|root,COG5306@1|root,COG1520@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,COG5306@2|Bacteria,4NNUN@976|Bacteroidetes,1IKME@117743|Flavobacteriia,2NXAD@237|Flavobacterium	976|Bacteroidetes	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,I-set,Ig_3,SBBP
CMS1_k127_5524812_2	204669.Acid345_0761	1.325e-48	179.0	COG2080@1|root,COG2080@2|Bacteria,3Y4DP@57723|Acidobacteria,2JJ2F@204432|Acidobacteriia	204432|Acidobacteriia	C	2Fe-2S -binding	-	-	-	ko:K13483	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002	-	-	-	Fer2,Fer2_2,TAT_signal
CMS1_k127_5524812_1	1047013.AQSP01000139_gene2340	7.357e-70	249.0	COG1975@1|root,COG1975@2|Bacteria,2NPTS@2323|unclassified Bacteria	2|Bacteria	O	XdhC and CoxI family	pucA	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
CMS1_k127_5524812_3	1047013.AQSP01000139_gene2341	2.552e-41	161.0	COG2068@1|root,COG2068@2|Bacteria,2NPK5@2323|unclassified Bacteria	2|Bacteria	S	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	mocA	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019538,GO:0019637,GO:0019720,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061602,GO:0070567,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902759,GO:1902760	1.1.1.328,2.7.7.76	ko:K07141,ko:K19190	ko00760,ko00790,ko01120,map00760,map00790,map01120	-	R10131,R10132,R11582	RC03053	ko00000,ko00001,ko01000	-	-	iAPECO1_1312.APECO1_3649,iB21_1397.B21_02672,iECABU_c1320.ECABU_c31580,iECBD_1354.ECBD_0860,iECB_1328.ECB_02710,iECD_1391.ECD_02710,iEcHS_1320.EcHS_A3037	HD,HTH_1,NTP_transf_3
CMS1_k127_5524812_0	1123278.KB893616_gene3402	1.422e-98	334.0	COG3119@1|root,COG3119@2|Bacteria,4NHH7@976|Bacteroidetes,47T8D@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CMS1_k127_5525216_1	1121468.AUBR01000050_gene2015	2.574e-23	110.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,24HHW@186801|Clostridia,42G4C@68295|Thermoanaerobacterales	186801|Clostridia	U	PFAM Peptidase S24 S26A S26B, conserved region	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
CMS1_k127_5525216_3	269799.Gmet_2656	2.488e-09	62.0	2EG51@1|root,339WY@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5525216_0	1408473.JHXO01000007_gene862	9.091e-36	143.0	COG0526@1|root,COG0526@2|Bacteria,4NR1K@976|Bacteroidetes,2FS53@200643|Bacteroidia	976|Bacteroidetes	CO	Redoxin family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
CMS1_k127_5525216_2	1408422.JHYF01000001_gene2963	1.453e-15	82.0	2DH0V@1|root,2ZY0A@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5529423_1	56110.Oscil6304_0870	3.985e-22	112.0	COG2319@1|root,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1H7DY@1150|Oscillatoriales	1117|Cyanobacteria	A	Wd40 repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_35,WD40
CMS1_k127_5529423_0	345341.KUTG_07862	3.498e-32	139.0	COG1609@1|root,COG1609@2|Bacteria,2IE2U@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	GntR,Peripla_BP_3
CMS1_k127_5529423_3	886293.Sinac_4844	4.036e-16	91.0	COG2165@1|root,COG2165@2|Bacteria,2J2S5@203682|Planctomycetes	203682|Planctomycetes	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CMS1_k127_5529423_2	247490.KSU1_C1333	2.103e-18	96.0	COG4968@1|root,COG4968@2|Bacteria,2J519@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CMS1_k127_5543081_0	595460.RRSWK_05477	2.14e-190	611.0	COG0657@1|root,COG0657@2|Bacteria	2|Bacteria	I	acetylesterase activity	-	-	3.2.1.51	ko:K15923	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	GH95	-	Glyco_hyd_65N_2,Peptidase_S9
CMS1_k127_5543081_3	247490.KSU1_C1333	3.565e-14	83.0	COG4968@1|root,COG4968@2|Bacteria,2J519@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CMS1_k127_5543081_2	1121904.ARBP01000042_gene4905	2.462e-125	429.0	COG3292@1|root,COG3292@2|Bacteria,4NF9I@976|Bacteroidetes,47XHD@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
CMS1_k127_5543081_1	1121904.ARBP01000013_gene390	5.68e-175	559.0	COG3669@1|root,COG3669@2|Bacteria,4NEAP@976|Bacteroidetes,47JG2@768503|Cytophagia	976|Bacteroidetes	G	Alpha-L-fucosidase C-terminal domain	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Fucosidase_C
CMS1_k127_5543081_4	251221.35213025	1.54e-08	66.0	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,Kelch_1,Kelch_6
CMS1_k127_5545663_1	1121918.ARWE01000001_gene1327	5.775e-129	421.0	COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,42QE5@68525|delta/epsilon subdivisions,2WM8R@28221|Deltaproteobacteria,43S58@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	NQR2, RnfD, RnfE family	-	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
CMS1_k127_5545663_0	391625.PPSIR1_12063	8.772e-177	565.0	COG1726@1|root,COG1726@2|Bacteria,1MU36@1224|Proteobacteria,42PMT@68525|delta/epsilon subdivisions,2WK84@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrA	-	1.6.5.8	ko:K00346	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_10,NQRA,NQRA_SLBB
CMS1_k127_5549905_3	661478.OP10G_0540	1.027e-41	163.0	COG3525@1|root,COG3525@2|Bacteria	2|Bacteria	G	beta-N-acetylhexosaminidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4838,F5_F8_type_C,Glyco_hydro_67N
CMS1_k127_5549905_1	452637.Oter_2196	3.405e-137	450.0	COG0673@1|root,COG0673@2|Bacteria,46U95@74201|Verrucomicrobia,3K969@414999|Opitutae	414999|Opitutae	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_5549905_0	697281.Mahau_1207	7.454e-176	568.0	COG2730@1|root,COG2730@2|Bacteria,1V9GI@1239|Firmicutes,24KYA@186801|Clostridia	186801|Clostridia	G	Domain of unknown function (DUF5060)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4038,DUF5060
CMS1_k127_5549905_2	616991.JPOO01000003_gene29	9.028e-91	309.0	2DDE1@1|root,2ZHNZ@2|Bacteria,4NNSM@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
CMS1_k127_5558643_1	867903.ThesuDRAFT_00548	3.43e-78	267.0	COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,3WCDB@538999|Clostridiales incertae sedis	186801|Clostridia	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
CMS1_k127_5558643_0	1125863.JAFN01000001_gene892	7.64e-162	519.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,42MFM@68525|delta/epsilon subdivisions,2WIQ3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
CMS1_k127_5560130_0	1033732.CAHI01000007_gene2064	1.807e-137	467.0	COG3345@1|root,COG3345@2|Bacteria	2|Bacteria	G	alpha-galactosidase	rafA	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_36C,Glyco_hydro_36N,Melibiase
CMS1_k127_5570873_1	234267.Acid_1785	2.025e-67	245.0	COG1020@1|root,COG1020@2|Bacteria,3Y61Y@57723|Acidobacteria	57723|Acidobacteria	H	Protein of unknown function (DUF1298)	-	-	2.3.1.20	ko:K00635	ko00561,ko01100,map00561,map01100	M00089	R02251	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1298,WES_acyltransf
CMS1_k127_5570873_4	933262.AXAM01000004_gene2370	2.954e-10	67.0	2E3F6@1|root,32YE2@2|Bacteria,1NDBB@1224|Proteobacteria,42WNV@68525|delta/epsilon subdivisions,2WRV2@28221|Deltaproteobacteria,2MKYS@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5570873_2	479434.Sthe_1123	4.684e-66	236.0	COG0451@1|root,COG0451@2|Bacteria,2GBGX@200795|Chloroflexi,27Y3C@189775|Thermomicrobia	189775|Thermomicrobia	M	Polysaccharide biosynthesis protein	-	-	1.1.1.281	ko:K15856	ko00051,ko00520,map00051,map00520	-	R03397,R03399	RC00182	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
CMS1_k127_5570873_0	1297742.A176_03413	1.681e-150	487.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,42MDV@68525|delta/epsilon subdivisions,2WJ3T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
CMS1_k127_5570873_3	1499967.BAYZ01000073_gene2049	4.709e-47	194.0	COG3119@1|root,COG3119@2|Bacteria,2NR0Q@2323|unclassified Bacteria	2|Bacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	CBM60,Sulfatase
CMS1_k127_5572963_0	1097668.BYI23_C009790	4.721e-23	101.0	COG1309@1|root,COG1309@2|Bacteria,1RAHE@1224|Proteobacteria,2W325@28216|Betaproteobacteria,1K6BY@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS1_k127_5572963_3	1068980.ARVW01000001_gene254	0.000267	45.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	2.3.1.57	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	M00135	R01154	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7,FR47
CMS1_k127_5572963_2	1068980.ARVW01000001_gene254	9.088e-09	59.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	2.3.1.57	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	M00135	R01154	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7,FR47
CMS1_k127_5576526_0	234267.Acid_7897	1.622e-181	587.0	COG3303@1|root,COG3303@2|Bacteria,3Y84F@57723|Acidobacteria	57723|Acidobacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5581921_2	452637.Oter_1961	1.315e-79	274.0	COG0300@1|root,COG0318@1|root,COG3321@1|root,COG0300@2|Bacteria,COG0318@2|Bacteria,COG3321@2|Bacteria,46SCA@74201|Verrucomicrobia	74201|Verrucomicrobia	Q	PKS_DH	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,ketoacyl-synt
CMS1_k127_5581921_4	1242864.D187_001823	7.305e-08	55.0	COG0384@1|root,COG0384@2|Bacteria,1R9X4@1224|Proteobacteria,42QYJ@68525|delta/epsilon subdivisions,2WN82@28221|Deltaproteobacteria,2YX3U@29|Myxococcales	28221|Deltaproteobacteria	S	Phenazine biosynthesis-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
CMS1_k127_5581921_3	5722.XP_001326029.1	1.643e-48	181.0	COG0062@1|root,KOG2585@2759|Eukaryota	2759|Eukaryota	D	NADPHX epimerase activity	-	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
CMS1_k127_5581921_0	269799.Gmet_0138	6.345e-142	467.0	COG5316@1|root,COG5316@2|Bacteria,1QCVP@1224|Proteobacteria,42QA4@68525|delta/epsilon subdivisions,2WKD1@28221|Deltaproteobacteria,43SDE@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139,DUF4140
CMS1_k127_5581921_1	269799.Gmet_0138	1.28e-105	352.0	COG5316@1|root,COG5316@2|Bacteria,1QCVP@1224|Proteobacteria,42QA4@68525|delta/epsilon subdivisions,2WKD1@28221|Deltaproteobacteria,43SDE@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139,DUF4140
CMS1_k127_5584754_1	35754.JNYJ01000001_gene7128	4.188e-19	89.0	COG0143@1|root,COG0143@2|Bacteria,2GK4S@201174|Actinobacteria,4DC0Z@85008|Micromonosporales	201174|Actinobacteria	J	tRNA synthetases class I (M)	-	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1g
CMS1_k127_5584754_2	909613.UO65_2877	6.13e-08	65.0	COG3420@1|root,COG3420@2|Bacteria,2I0IB@201174|Actinobacteria,4E1TX@85010|Pseudonocardiales	201174|Actinobacteria	P	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
CMS1_k127_5584754_0	1304880.JAGB01000002_gene1634	1.424e-42	162.0	COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,247NR@186801|Clostridia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
CMS1_k127_5592064_0	383372.Rcas_2834	5.833e-45	169.0	COG4154@1|root,COG4154@2|Bacteria	2|Bacteria	G	fucose binding	fucU	-	5.1.3.29	ko:K02431	-	-	R10764	RC00563	ko00000,ko01000	-	-	-	RbsD_FucU
CMS1_k127_5592064_1	744872.Spica_1146	4.694e-05	49.0	COG0457@1|root,COG0457@2|Bacteria,2J58A@203691|Spirochaetes	203691|Spirochaetes	S	TPR domain protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_8
CMS1_k127_5593207_1	997346.HMPREF9374_1633	1.122e-36	146.0	COG0584@1|root,COG0584@2|Bacteria,1UGF1@1239|Firmicutes,4H9QE@91061|Bacilli	91061|Bacilli	C	glycerophosphoryl diester phosphodiesterase	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	DUF1080,GDPD
CMS1_k127_5593207_2	357808.RoseRS_3371	7.276e-34	140.0	COG3437@1|root,COG5002@1|root,COG3437@2|Bacteria,COG5002@2|Bacteria,2GBI7@200795|Chloroflexi,376P2@32061|Chloroflexia	32061|Chloroflexia	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HD,HD_5,PAS,Response_reg
CMS1_k127_5593207_3	247490.KSU1_C1333	2.764e-14	83.0	COG4968@1|root,COG4968@2|Bacteria,2J519@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CMS1_k127_5593207_0	234267.Acid_4005	2.93e-64	233.0	COG1053@1|root,COG1053@2|Bacteria,3Y6S5@57723|Acidobacteria	57723|Acidobacteria	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
CMS1_k127_5603950_4	1304880.JAGB01000001_gene658	1.654e-05	53.0	COG0412@1|root,COG0412@2|Bacteria,1TQQS@1239|Firmicutes,24DCW@186801|Clostridia	186801|Clostridia	Q	Abhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_7,BAAT_C
CMS1_k127_5603950_1	1267535.KB906767_gene473	1.989e-81	287.0	28JXN@1|root,30T38@2|Bacteria,3Y61P@57723|Acidobacteria	57723|Acidobacteria	S	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
CMS1_k127_5603950_0	706587.Desti_2572	0.0	1406.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,42MVK@68525|delta/epsilon subdivisions,2WKEN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	-	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
CMS1_k127_5603950_3	1122612.AUBA01000005_gene2766	1.483e-10	63.0	COG1861@1|root,COG1861@2|Bacteria,1QU5J@1224|Proteobacteria,2TW1M@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Transposase DDE domain group 1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
CMS1_k127_5603950_2	314287.GB2207_10116	2.901e-43	165.0	COG2015@1|root,COG2015@2|Bacteria,1MU82@1224|Proteobacteria,1S468@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Alkyl sulfatase dimerisation	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_dimr,Lactamase_B
CMS1_k127_5607111_0	1125863.JAFN01000001_gene2794	8.215e-185	591.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,42MD6@68525|delta/epsilon subdivisions,2WMNX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Cytochrome b b6 domain	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B_C,Cytochrome_B
CMS1_k127_5607111_3	1125863.JAFN01000001_gene2795	1.32e-30	128.0	COG0723@1|root,COG0723@2|Bacteria,1NINP@1224|Proteobacteria,42VKD@68525|delta/epsilon subdivisions,2WRHY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Rieske 2Fe-2S domain	pcmE	-	1.10.9.1	ko:K02636,ko:K03886	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00151,M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Rieske
CMS1_k127_5607111_1	1125863.JAFN01000001_gene2796	4.414e-166	543.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,42PJ7@68525|delta/epsilon subdivisions,2WMEM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Fer4_7,Pyr_redox_2
CMS1_k127_5607111_5	309807.SRU_0748	2.273e-27	115.0	COG1959@1|root,COG1959@2|Bacteria,4NURI@976|Bacteroidetes,1FJGW@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
CMS1_k127_5607111_6	1121451.DESAM_22038	4.197e-23	109.0	COG2231@1|root,COG2231@2|Bacteria,1RDJ8@1224|Proteobacteria,42QYA@68525|delta/epsilon subdivisions,2WNGC@28221|Deltaproteobacteria,2MB49@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	PFAM HhH-GPD family protein	nth	-	-	ko:K07457	-	-	-	-	ko00000	-	-	-	HhH-GPD
CMS1_k127_5607111_2	237368.SCABRO_01300	6.974e-56	206.0	COG1533@1|root,COG1533@2|Bacteria,2IX0U@203682|Planctomycetes	203682|Planctomycetes	L	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
CMS1_k127_5607111_4	1123035.ARLA01000028_gene1836	1.717e-29	129.0	COG2211@1|root,COG5309@1|root,COG2211@2|Bacteria,COG5309@2|Bacteria,4NE3B@976|Bacteroidetes,1HZMJ@117743|Flavobacteriia,4C36I@83612|Psychroflexus	976|Bacteroidetes	G	Glycosyl hydrolases family 17	uidB	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	Glyco_hydro_17,MFS_2
CMS1_k127_5607770_3	246194.CHY_2199	2.055e-124	409.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,42FGX@68295|Thermoanaerobacterales	186801|Clostridia	H	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
CMS1_k127_5607770_12	861299.J421_4375	6.39e-52	191.0	COG1595@1|root,COG1595@2|Bacteria,1ZTNR@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_5607770_26	1117315.AHCA01000009_gene429	2.728e-06	58.0	2CKCT@1|root,32SC5@2|Bacteria,1N1BJ@1224|Proteobacteria,1S8RE@1236|Gammaproteobacteria,2Q2TX@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5607770_13	1384056.N787_04785	2.819e-47	181.0	COG3595@1|root,COG3595@2|Bacteria,1P19T@1224|Proteobacteria,1RRSR@1236|Gammaproteobacteria,1X62K@135614|Xanthomonadales	135614|Xanthomonadales	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
CMS1_k127_5607770_7	338963.Pcar_2422	9.559e-77	265.0	COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,42N84@68525|delta/epsilon subdivisions,2WJKT@28221|Deltaproteobacteria,43THZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Dihydrodipicolinate reductase, C-terminus	dapB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
CMS1_k127_5607770_5	247490.KSU1_C1016	4.573e-95	320.0	COG0329@1|root,COG0329@2|Bacteria,2IXII@203682|Planctomycetes	203682|Planctomycetes	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
CMS1_k127_5607770_2	457570.Nther_2910	9.066e-127	422.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia	186801|Clostridia	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
CMS1_k127_5607770_16	880073.Calab_2408	2.172e-32	132.0	COG0359@1|root,COG0359@2|Bacteria,2NPX4@2323|unclassified Bacteria	2|Bacteria	J	Binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
CMS1_k127_5607770_27	335543.Sfum_3186	6.811e-06	58.0	COG4241@1|root,COG4241@2|Bacteria,1N4XJ@1224|Proteobacteria,42QCS@68525|delta/epsilon subdivisions,2WKDT@28221|Deltaproteobacteria,2MS2Q@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Predicted membrane protein (DUF2232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2232
CMS1_k127_5607770_20	1121289.JHVL01000038_gene2981	2.525e-21	96.0	COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,24MQV@186801|Clostridia,36KGE@31979|Clostridiaceae	186801|Clostridia	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
CMS1_k127_5607770_17	583355.Caka_1586	1.055e-28	121.0	COG0629@1|root,COG0629@2|Bacteria,46VZR@74201|Verrucomicrobia,3K80H@414999|Opitutae	414999|Opitutae	L	Single-stranded DNA-binding protein	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
CMS1_k127_5607770_21	639282.DEFDS_1987	6.397e-21	98.0	COG0360@1|root,COG0360@2|Bacteria,2GG0Y@200930|Deferribacteres	200930|Deferribacteres	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
CMS1_k127_5607770_9	370438.PTH_0857	1.159e-73	276.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,249VR@186801|Clostridia,26014@186807|Peptococcaceae	186801|Clostridia	S	DNA internalization-related competence protein ComEC Rec2	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
CMS1_k127_5607770_11	247490.KSU1_B0345	6.73e-61	233.0	COG1807@1|root,COG1807@2|Bacteria,2IZ8J@203682|Planctomycetes	203682|Planctomycetes	M	glycosyl transferase family 39	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2,PMT_2
CMS1_k127_5607770_15	1304888.ATWF01000001_gene1100	6.061e-35	142.0	COG3952@1|root,COG3952@2|Bacteria,2GFV1@200930|Deferribacteres	200930|Deferribacteres	S	Lipid A Biosynthesis N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	LAB_N
CMS1_k127_5607770_10	247490.KSU1_D0367	1.58e-63	225.0	COG0463@1|root,COG0463@2|Bacteria,2IXAV@203682|Planctomycetes	203682|Planctomycetes	M	PFAM Glycosyl transferase family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
CMS1_k127_5607770_23	319236.JCM19294_2259	1.874e-13	76.0	294EW@1|root,2ZRUR@2|Bacteria,4NPA3@976|Bacteroidetes,1I38U@117743|Flavobacteriia,3HKIV@363408|Nonlabens	976|Bacteroidetes	S	Protein of unknown function (DUF1569)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1569
CMS1_k127_5607770_18	646529.Desaci_3616	1.709e-27	119.0	COG1670@1|root,COG1670@2|Bacteria,1VNWY@1239|Firmicutes,24SPX@186801|Clostridia	186801|Clostridia	J	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS1_k127_5607770_0	886293.Sinac_3887	2.364e-170	541.0	COG2355@1|root,COG2355@2|Bacteria,2IWUV@203682|Planctomycetes	203682|Planctomycetes	E	Zn-dependent dipeptidase, microsomal dipeptidase	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
CMS1_k127_5607770_24	1173025.GEI7407_3302	3.775e-08	66.0	COG2912@1|root,COG2912@2|Bacteria,1G11S@1117|Cyanobacteria,1H8P0@1150|Oscillatoriales	1117|Cyanobacteria	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	TPR_9,Transglut_core2
CMS1_k127_5607770_19	6412.HelroP103978	4.982e-23	114.0	COG3914@1|root,KOG4626@2759|Eukaryota,38EM5@33154|Opisthokonta,3BC3N@33208|Metazoa,3CWN6@33213|Bilateria	33208|Metazoa	GOT	UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa	OGT	GO:0000003,GO:0000123,GO:0000785,GO:0000791,GO:0001678,GO:0001932,GO:0001933,GO:0001934,GO:0002119,GO:0002164,GO:0002237,GO:0003674,GO:0003824,GO:0004721,GO:0004722,GO:0005488,GO:0005515,GO:0005543,GO:0005547,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0006040,GO:0006041,GO:0006047,GO:0006048,GO:0006073,GO:0006091,GO:0006109,GO:0006110,GO:0006111,GO:0006112,GO:0006139,GO:0006140,GO:0006325,GO:0006355,GO:0006357,GO:0006464,GO:0006470,GO:0006473,GO:0006475,GO:0006479,GO:0006486,GO:0006493,GO:0006508,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006996,GO:0007005,GO:0007154,GO:0007165,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0007444,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0007626,GO:0008080,GO:0008134,GO:0008150,GO:0008152,GO:0008194,GO:0008213,GO:0008219,GO:0008289,GO:0008361,GO:0008375,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009226,GO:0009605,GO:0009607,GO:0009617,GO:0009636,GO:0009719,GO:0009725,GO:0009743,GO:0009746,GO:0009749,GO:0009791,GO:0009888,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009966,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010562,GO:0010563,GO:0010604,GO:0010605,GO:0010628,GO:0010638,GO:0010646,GO:0010675,GO:0010799,GO:0010801,GO:0010876,GO:0010906,GO:0010941,GO:0012501,GO:0012505,GO:0015980,GO:0016020,GO:0016043,GO:0016262,GO:0016311,GO:0016407,GO:0016410,GO:0016485,GO:0016569,GO:0016570,GO:0016571,GO:0016573,GO:0016579,GO:0016740,GO:0016746,GO:0016747,GO:0016757,GO:0016758,GO:0016787,GO:0016788,GO:0016791,GO:0018022,GO:0018023,GO:0018130,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019538,GO:0019725,GO:0019904,GO:0019915,GO:0022607,GO:0023051,GO:0023052,GO:0030141,GO:0030162,GO:0030246,GO:0030808,GO:0030811,GO:0030900,GO:0031056,GO:0031058,GO:0031060,GO:0031062,GO:0031248,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031330,GO:0031396,GO:0031397,GO:0031399,GO:0031400,GO:0031401,GO:0031410,GO:0031667,GO:0031974,GO:0031981,GO:0031982,GO:0032259,GO:0032268,GO:0032269,GO:0032270,GO:0032386,GO:0032387,GO:0032434,GO:0032435,GO:0032496,GO:0032501,GO:0032502,GO:0032535,GO:0032868,GO:0032869,GO:0032870,GO:0032879,GO:0032880,GO:0032922,GO:0032991,GO:0033036,GO:0033043,GO:0033044,GO:0033135,GO:0033137,GO:0033157,GO:0033218,GO:0033500,GO:0033993,GO:0034284,GO:0034641,GO:0034645,GO:0034654,GO:0034968,GO:0035020,GO:0035091,GO:0035220,GO:0035295,GO:0035556,GO:0036094,GO:0036211,GO:0036477,GO:0040024,GO:0042176,GO:0042177,GO:0042221,GO:0042277,GO:0042325,GO:0042326,GO:0042327,GO:0042578,GO:0042588,GO:0042592,GO:0042593,GO:0042995,GO:0043005,GO:0043025,GO:0043167,GO:0043168,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043255,GO:0043412,GO:0043413,GO:0043414,GO:0043434,GO:0043467,GO:0043470,GO:0043543,GO:0043933,GO:0043967,GO:0043981,GO:0043982,GO:0043984,GO:0044042,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0044271,GO:0044281,GO:0044297,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0045475,GO:0045793,GO:0045861,GO:0045862,GO:0045893,GO:0045935,GO:0045936,GO:0045937,GO:0045944,GO:0046349,GO:0046483,GO:0046578,GO:0046626,GO:0048015,GO:0048017,GO:0048029,GO:0048311,GO:0048312,GO:0048471,GO:0048511,GO:0048512,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048731,GO:0048856,GO:0048878,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051051,GO:0051056,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051193,GO:0051196,GO:0051223,GO:0051224,GO:0051235,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051276,GO:0051291,GO:0051568,GO:0051604,GO:0051640,GO:0051641,GO:0051646,GO:0051704,GO:0051707,GO:0051716,GO:0055082,GO:0055086,GO:0055114,GO:0060255,GO:0060322,GO:0060341,GO:0060429,GO:0060548,GO:0061085,GO:0061087,GO:0061136,GO:0062012,GO:0065003,GO:0065007,GO:0065008,GO:0070013,GO:0070085,GO:0070201,GO:0070206,GO:0070207,GO:0070208,GO:0070646,GO:0070647,GO:0070887,GO:0071216,GO:0071219,GO:0071222,GO:0071310,GO:0071322,GO:0071326,GO:0071331,GO:0071333,GO:0071375,GO:0071396,GO:0071417,GO:0071495,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0080134,GO:0080135,GO:0080182,GO:0090066,GO:0090087,GO:0090313,GO:0090315,GO:0090317,GO:0097237,GO:0097363,GO:0097458,GO:0097708,GO:0099503,GO:0120025,GO:0140096,GO:1900037,GO:1900038,GO:1900076,GO:1900180,GO:1900182,GO:1900371,GO:1900542,GO:1901071,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901799,GO:1901981,GO:1902275,GO:1902493,GO:1902494,GO:1902531,GO:1902680,GO:1903050,GO:1903051,GO:1903320,GO:1903321,GO:1903362,GO:1903363,GO:1903426,GO:1903428,GO:1903506,GO:1903508,GO:1903533,GO:1903578,GO:1903827,GO:1903828,GO:1903829,GO:1904950,GO:1905269,GO:1905475,GO:1905476,GO:1990234,GO:2000058,GO:2000059,GO:2000112,GO:2000377,GO:2000379,GO:2001141,GO:2001169,GO:2001252	2.4.1.255	ko:K09667	ko00514,ko04931,map00514,map04931	-	R09304,R09676	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003,ko03036	-	GT41	-	Glyco_transf_41,TPR_1,TPR_11,TPR_2,TPR_8
CMS1_k127_5607770_6	1142394.PSMK_06950	4.348e-92	309.0	COG5285@1|root,COG5285@2|Bacteria	2|Bacteria	Q	dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
CMS1_k127_5607770_1	526222.Desal_3465	4.751e-141	456.0	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,42M1J@68525|delta/epsilon subdivisions,2WIQR@28221|Deltaproteobacteria,2M7RW@213115|Desulfovibrionales	28221|Deltaproteobacteria	D	Cell shape determining protein MreB Mrl	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
CMS1_k127_5607770_22	1285586.H131_15623	1.231e-13	82.0	COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,4HB0K@91061|Bacilli,3IVW1@400634|Lysinibacillus	91061|Bacilli	M	Involved in formation and maintenance of cell shape	mreC	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0022603,GO:0022604,GO:0030428,GO:0042546,GO:0043621,GO:0044085,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
CMS1_k127_5607770_4	909663.KI867150_gene2102	7.259e-112	388.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,42M1S@68525|delta/epsilon subdivisions,2WJ02@28221|Deltaproteobacteria,2MQ74@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Penicillin-binding protein, dimerisation domain	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_0928	PBP_dimer,Transpeptidase
CMS1_k127_5607770_8	1120985.AUMI01000014_gene1174	7.385e-76	276.0	COG0772@1|root,COG0772@2|Bacteria,1TPGH@1239|Firmicutes,4H21I@909932|Negativicutes	909932|Negativicutes	M	Peptidoglycan polymerase that is essential for cell wall elongation	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
CMS1_k127_5607770_14	118005.AWNK01000012_gene40	1.303e-38	151.0	COG1530@1|root,COG1530@2|Bacteria	2|Bacteria	J	ribonuclease E activity	rng	GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005856,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008996,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
CMS1_k127_5610376_0	1280950.HJO_14902	5.019e-295	923.0	COG1629@1|root,COG4771@2|Bacteria,1R4PY@1224|Proteobacteria,2U3FF@28211|Alphaproteobacteria,43ZA5@69657|Hyphomonadaceae	28211|Alphaproteobacteria	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
CMS1_k127_5610376_1	501479.ACNW01000062_gene2740	2.706e-70	240.0	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,2TSGX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
CMS1_k127_5617703_1	1288963.ADIS_4730	1.7e-65	229.0	COG0673@1|root,COG3733@1|root,COG0673@2|Bacteria,COG3733@2|Bacteria,4NN43@976|Bacteroidetes,47UBC@768503|Cytophagia	976|Bacteroidetes	Q	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_5617703_3	1117318.PRUB_23591	1.016e-48	188.0	COG0673@1|root,COG0673@2|Bacteria,1MZIG@1224|Proteobacteria,1RS5T@1236|Gammaproteobacteria,2Q1GP@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	dehydrogenases and related proteins	ygjR	-	-	ko:K22230	ko00562,ko01120,map00562,map01120	-	R09954	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_5617703_4	886293.Sinac_3694	1.114e-36	150.0	COG3568@1|root,COG3568@2|Bacteria,2IZ9W@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Endonuclease Exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CMS1_k127_5617703_0	1120973.AQXL01000124_gene2329	6.529e-75	264.0	COG0673@1|root,COG0673@2|Bacteria,1TQ72@1239|Firmicutes,4HAGN@91061|Bacilli	91061|Bacilli	K	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_5617703_5	204669.Acid345_4514	2.315e-32	136.0	COG2121@1|root,COG2121@2|Bacteria,3Y4VJ@57723|Acidobacteria,2JJE4@204432|Acidobacteriia	204432|Acidobacteriia	S	Domain of unknown function (DUF374)	-	-	-	ko:K09778	-	-	-	-	ko00000	-	-	-	DUF374
CMS1_k127_5617703_2	644282.Deba_1325	2.358e-53	199.0	COG1893@1|root,COG1893@2|Bacteria,1P0AW@1224|Proteobacteria,42QZK@68525|delta/epsilon subdivisions,2WPP6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
CMS1_k127_562291_5	1550091.JROE01000019_gene3835	1.357e-08	65.0	COG2885@1|root,COG2885@2|Bacteria,4NP5H@976|Bacteroidetes,1IUBK@117747|Sphingobacteriia	976|Bacteroidetes	M	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
CMS1_k127_562291_3	323261.Noc_2967	1.304e-41	160.0	COG1959@1|root,COG1959@2|Bacteria,1N05H@1224|Proteobacteria,1S8SJ@1236|Gammaproteobacteria,1X0YM@135613|Chromatiales	135613|Chromatiales	K	transcriptional regulator, Rrf2 family	-	-	-	ko:K13771	ko05132,map05132	-	-	-	ko00000,ko00001,ko03000	-	-	-	Rrf2
CMS1_k127_562291_1	1232410.KI421415_gene3092	5.333e-107	363.0	COG1232@1|root,COG1232@2|Bacteria,1R0KQ@1224|Proteobacteria,42NBG@68525|delta/epsilon subdivisions,2WKMN@28221|Deltaproteobacteria,43SUB@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	hemY	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
CMS1_k127_562291_0	483219.LILAB_35155	4.436e-143	469.0	COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,42M87@68525|delta/epsilon subdivisions,2WMB0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
CMS1_k127_562291_2	1380391.JIAS01000011_gene4645	1.557e-105	360.0	COG3119@1|root,COG3119@2|Bacteria,1MV0B@1224|Proteobacteria,2TRI6@28211|Alphaproteobacteria,2JQCU@204441|Rhodospirillales	204441|Rhodospirillales	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CMS1_k127_562291_4	926569.ANT_29620	5.589e-39	149.0	COG1180@1|root,COG1180@2|Bacteria,2G6B2@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Radical SAM domain protein	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
CMS1_k127_5624232_0	471870.BACINT_04450	3.699e-110	401.0	COG0412@1|root,COG0412@2|Bacteria,4NIXW@976|Bacteroidetes,2FN6X@200643|Bacteroidia,4AKMB@815|Bacteroidaceae	976|Bacteroidetes	Q	COG COG1073 Hydrolases of the alpha beta superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_7,Pec_lyase,Peptidase_S9
CMS1_k127_5624232_1	269799.Gmet_1500	1.703e-27	118.0	29R89@1|root,30C9N@2|Bacteria,1NTEP@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5625018_7	330214.NIDE2388	6.596e-20	106.0	29R89@1|root,30C9N@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5625018_4	1123242.JH636434_gene4080	9.144e-55	206.0	COG1073@1|root,COG1073@2|Bacteria,2IWT8@203682|Planctomycetes	203682|Planctomycetes	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5625018_0	1121904.ARBP01000017_gene5093	2.204e-91	310.0	COG1409@1|root,COG1409@2|Bacteria,4NFAP@976|Bacteroidetes,47V4E@768503|Cytophagia	976|Bacteroidetes	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Fn3_assoc,Metallophos,PA14
CMS1_k127_5625018_11	944546.ABED_1159	6.712e-06	57.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,42QX3@68525|delta/epsilon subdivisions,2YP2T@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	O	anaerobic ribonucleoside-triphosphate reductase activating protein	nrdG	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
CMS1_k127_5625018_5	1192034.CAP_1962	2.617e-51	194.0	COG3344@1|root,COG3344@2|Bacteria,1R44F@1224|Proteobacteria,42WGB@68525|delta/epsilon subdivisions,2WQ7V@28221|Deltaproteobacteria,2YZ1Y@29|Myxococcales	28221|Deltaproteobacteria	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	RVT_1
CMS1_k127_5625018_3	211165.AJLN01000109_gene179	3.163e-65	225.0	COG0432@1|root,COG0432@2|Bacteria,1G61Z@1117|Cyanobacteria,1JKCA@1189|Stigonemataceae	1117|Cyanobacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
CMS1_k127_5625018_2	748727.CLJU_c12580	2.146e-66	233.0	COG2738@1|root,COG2738@2|Bacteria,1TPD3@1239|Firmicutes,2490Y@186801|Clostridia,36FA7@31979|Clostridiaceae	186801|Clostridia	S	zinc metallopeptidase	yugP	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
CMS1_k127_5625018_10	398512.JQKC01000025_gene3153	8.44e-11	71.0	COG1664@1|root,COG1664@2|Bacteria,1VEVU@1239|Firmicutes,24QT5@186801|Clostridia,3WPDC@541000|Ruminococcaceae	186801|Clostridia	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
CMS1_k127_5625018_6	404589.Anae109_1955	7.892e-48	184.0	COG0455@1|root,COG0455@2|Bacteria,1R8IW@1224|Proteobacteria,42R3H@68525|delta/epsilon subdivisions,2WMNY@28221|Deltaproteobacteria,2YUZU@29|Myxococcales	28221|Deltaproteobacteria	D	NUBPL iron-transfer P-loop NTPase	-	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	AAA_31,CbiA,HTH_25,ParA
CMS1_k127_5625018_1	1121428.DESHY_160142___1	7.991e-89	301.0	COG0320@1|root,COG0320@2|Bacteria,1TQM4@1239|Firmicutes,2495Q@186801|Clostridia,2619Z@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,LIAS_N,Radical_SAM
CMS1_k127_5625018_8	1457393.AZ09_12090	5.364e-16	80.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2TRN7@28211|Alphaproteobacteria,2JQ3A@204441|Rhodospirillales	204441|Rhodospirillales	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes	lpd	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim
CMS1_k127_5625018_9	765910.MARPU_08385	7.411e-11	66.0	COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,1RPEU@1236|Gammaproteobacteria,1WWHB@135613|Chromatiales	135613|Chromatiales	E	homoserine dehydrogenase	-	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
CMS1_k127_5639037_0	335543.Sfum_1457	0.0	1052.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJVV@28221|Deltaproteobacteria,2MR4N@213462|Syntrophobacterales	28221|Deltaproteobacteria	V	Protein export membrane protein	bepE	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
CMS1_k127_5639037_1	56780.SYN_02948	1.343e-25	110.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,42Q4P@68525|delta/epsilon subdivisions,2WJHQ@28221|Deltaproteobacteria,2MR8F@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Biotin-lipoyl like	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
CMS1_k127_5648779_0	215803.DB30_8705	4.208e-06	59.0	COG0793@1|root,COG4932@1|root,COG0793@2|Bacteria,COG4932@2|Bacteria,1Q2N3@1224|Proteobacteria,4388W@68525|delta/epsilon subdivisions,2XA2N@28221|Deltaproteobacteria,2YXAB@29|Myxococcales	28221|Deltaproteobacteria	M	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,PDZ_2
CMS1_k127_5661499_0	797210.Halxa_0904	6.514e-136	447.0	2DZBD@1|root,2N5Z8@2157|Archaea,2Y4ZP@28890|Euryarchaeota,2403Y@183963|Halobacteria	183963|Halobacteria	S	BNR repeat-containing family member	-	-	-	-	-	-	-	-	-	-	-	-	BNR_4
CMS1_k127_5661499_1	243090.RB4876	1.482e-83	289.0	COG1398@1|root,COG1398@2|Bacteria,2IY69@203682|Planctomycetes	203682|Planctomycetes	I	COG1398 Fatty-acid desaturase	-	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
CMS1_k127_5661499_2	123214.PERMA_1705	3.894e-27	111.0	COG2360@1|root,COG2360@2|Bacteria	2|Bacteria	O	leucyltransferase activity	aat	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0044424,GO:0044464,GO:0140096	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
CMS1_k127_5663136_6	272134.KB731324_gene1782	4.616e-15	76.0	COG0596@1|root,COG0596@2|Bacteria,1GQ5T@1117|Cyanobacteria,1H97N@1150|Oscillatoriales	1117|Cyanobacteria	S	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)	menH	-	4.2.99.20	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08166	RC02148,RC02475	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1
CMS1_k127_5663136_1	517418.Ctha_1987	1.675e-146	467.0	COG0447@1|root,COG0447@2|Bacteria,1FDH0@1090|Chlorobi	1090|Chlorobi	H	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)	menB	-	4.1.3.36	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07263	RC01923	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS1_k127_5663136_4	518766.Rmar_0586	8.092e-93	315.0	COG1575@1|root,COG1575@2|Bacteria,4NGCJ@976|Bacteroidetes,1FIUJ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Belongs to the MenA family. Type 1 subfamily	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
CMS1_k127_5663136_5	309807.SRU_1354	3.218e-49	192.0	COG1441@1|root,COG1441@2|Bacteria,4PM5X@976|Bacteroidetes,1FJEH@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	-	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C
CMS1_k127_5663136_3	42256.RradSPS_2309	6.11e-104	355.0	COG0318@1|root,COG0318@2|Bacteria,2GN9C@201174|Actinobacteria,4CPCU@84995|Rubrobacteria	84995|Rubrobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.26	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04030	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C
CMS1_k127_5663136_0	1304880.JAGB01000001_gene978	1.523e-171	547.0	COG1904@1|root,COG1904@2|Bacteria,1TR4T@1239|Firmicutes,249B2@186801|Clostridia	186801|Clostridia	G	glucuronate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5663136_2	937777.Deipe_1360	6.446e-140	461.0	COG2407@1|root,COG2407@2|Bacteria	2|Bacteria	G	Converts the aldose L-fucose into the corresponding ketose L-fuculose	-	-	5.3.1.25,5.3.1.3	ko:K01818	ko00051,ko01120,map00051,map01120	-	R03163	RC00434	ko00000,ko00001,ko01000	-	-	-	Fucose_iso_C,Fucose_iso_N1,Fucose_iso_N2
CMS1_k127_5665448_1	1288963.ADIS_0133	9.546e-122	405.0	COG0673@1|root,COG0673@2|Bacteria,4NGHJ@976|Bacteroidetes,47NH0@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_5665448_0	439235.Dalk_3415	0.0	1063.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJN5@28221|Deltaproteobacteria,2MMWB@213118|Desulfobacterales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
CMS1_k127_5665448_2	439235.Dalk_3416	4.03e-116	389.0	COG0845@1|root,COG0845@2|Bacteria,1PEVY@1224|Proteobacteria,42ZAR@68525|delta/epsilon subdivisions,2WU8I@28221|Deltaproteobacteria,2MN1D@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3
CMS1_k127_5667768_4	484770.UFO1_1320	1.246e-17	89.0	COG0524@1|root,COG0524@2|Bacteria,1UYF8@1239|Firmicutes	1239|Firmicutes	G	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
CMS1_k127_5667768_1	926554.KI912662_gene1248	2.156e-36	141.0	COG0251@1|root,COG0251@2|Bacteria,1WK0P@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	PFAM Endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
CMS1_k127_5667768_3	269799.Gmet_1932	9.474e-35	149.0	COG0457@1|root,COG0457@2|Bacteria,1QXNU@1224|Proteobacteria,43C4R@68525|delta/epsilon subdivisions,2X7F5@28221|Deltaproteobacteria,43SFM@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Peptidase MA superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2,TPR_16,TPR_2,TPR_8
CMS1_k127_5667768_0	207559.Dde_1584	2.206e-68	243.0	COG2199@1|root,COG3706@2|Bacteria,1QUKY@1224|Proteobacteria,42NYY@68525|delta/epsilon subdivisions,2WKIY@28221|Deltaproteobacteria,2M8WM@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
CMS1_k127_5667768_8	1439940.BAY1663_02468	0.0007833	48.0	COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,1RMF4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Single-stranded-DNA-specific exonuclease	recJ	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008297,GO:0008409,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0035312,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0045145,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
CMS1_k127_5667768_7	886293.Sinac_6278	1.778e-05	58.0	COG4219@1|root,COG4219@2|Bacteria,2J205@203682|Planctomycetes	203682|Planctomycetes	KT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56,Thioredoxin_7
CMS1_k127_5667768_6	357808.RoseRS_0760	2.414e-08	67.0	COG0526@1|root,COG0526@2|Bacteria,2G737@200795|Chloroflexi,375V3@32061|Chloroflexia	32061|Chloroflexia	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,DnaJ
CMS1_k127_5667768_5	1223523.H340_13302	1.23e-11	68.0	COG0268@1|root,COG0268@2|Bacteria,2IQ73@201174|Actinobacteria	201174|Actinobacteria	J	Binds directly to 16S ribosomal RNA	rpsT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
CMS1_k127_5667768_2	518766.Rmar_1009	4.063e-35	147.0	COG0589@1|root,COG0589@2|Bacteria,4NFZ5@976|Bacteroidetes	976|Bacteroidetes	T	universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS1_k127_5669508_0	323098.Nwi_3099	2.159e-94	324.0	COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,1PBHA@1224|Proteobacteria,2TRQF@28211|Alphaproteobacteria,3JS1E@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	leucine-zipper of insertion element IS481	-	-	2.7.7.49	ko:K00986,ko:K07497	-	-	-	-	ko00000,ko01000	-	-	-	HTH_32,rve
CMS1_k127_5669508_2	436229.JOEH01000014_gene6129	3.002e-57	224.0	COG2319@1|root,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria,2NEAZ@228398|Streptacidiphilus	201174|Actinobacteria	T	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	WD40
CMS1_k127_5669508_7	340177.Cag_1026	1.044e-14	88.0	COG1404@1|root,COG1572@1|root,COG2264@1|root,COG2304@1|root,COG2706@1|root,COG2931@1|root,COG1404@2|Bacteria,COG1572@2|Bacteria,COG2264@2|Bacteria,COG2304@2|Bacteria,COG2706@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	prmA	-	3.5.1.28	ko:K01448,ko:K02687	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03009,ko03036	-	-	-	HemolysinCabind,Methyltransf_25,Methyltransf_31,PrmA,VCBS
CMS1_k127_5669508_3	243090.RB9128	2.679e-49	184.0	29CWT@1|root,2ZZUX@2|Bacteria	2|Bacteria	S	UPF0314 protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2585
CMS1_k127_5669508_1	867845.KI911784_gene2719	5.13e-59	218.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PKD,SBBP
CMS1_k127_5669508_6	755178.Cyan10605_2932	4.436e-28	132.0	COG2931@1|root,COG2931@2|Bacteria,1G91D@1117|Cyanobacteria	1117|Cyanobacteria	Q	Lectin C-type domain	-	-	-	-	-	-	-	-	-	-	-	-	Lectin_C
CMS1_k127_5669508_4	886293.Sinac_3442	1.203e-33	151.0	COG0526@1|root,COG1470@1|root,COG1595@1|root,COG0526@2|Bacteria,COG1470@2|Bacteria,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	AhpC-TSA,DUF4384,NPCBM_assoc,PEGA,Sigma70_r2,Sigma70_r4_2,Thioredoxin_8
CMS1_k127_5669508_5	106370.Francci3_2176	1.069e-32	140.0	2E3IT@1|root,32YH8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_567842_0	290397.Adeh_3062	9.892e-111	393.0	COG4262@1|root,COG4262@2|Bacteria,1QX9D@1224|Proteobacteria,42Q62@68525|delta/epsilon subdivisions,2WMHX@28221|Deltaproteobacteria,2YUT9@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
CMS1_k127_567842_4	1123276.KB893268_gene4926	0.0002308	53.0	COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,47JJJ@768503|Cytophagia	976|Bacteroidetes	P	TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CMS1_k127_567842_3	1396418.BATQ01000168_gene1822	1.963e-05	47.0	COG0551@1|root,COG0551@2|Bacteria,46V39@74201|Verrucomicrobia	74201|Verrucomicrobia	L	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
CMS1_k127_567842_1	1125863.JAFN01000001_gene2728	6.833e-45	174.0	COG0551@1|root,COG0551@2|Bacteria,1RCA8@1224|Proteobacteria,42R20@68525|delta/epsilon subdivisions,2WN67@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
CMS1_k127_567842_2	1249627.D779_1041	9.18e-17	85.0	COG0551@1|root,COG0551@2|Bacteria,1RCA8@1224|Proteobacteria	1224|Proteobacteria	L	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
CMS1_k127_5690941_6	1408428.JNJP01000014_gene886	8.611e-24	105.0	COG3836@1|root,COG3836@2|Bacteria,1MUSG@1224|Proteobacteria,42ZHZ@68525|delta/epsilon subdivisions,2WV2X@28221|Deltaproteobacteria,2MBDH@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	HpcH/HpaI aldolase/citrate lyase family	-	-	-	-	-	-	-	-	-	-	-	-	HpcH_HpaI
CMS1_k127_5690941_3	886293.Sinac_6000	1.747e-102	340.0	COG0388@1|root,COG0388@2|Bacteria,2IXKW@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.1.6	ko:K01431	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R00905,R04666,R08228	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase
CMS1_k127_5690941_5	1089547.KB913013_gene1005	2.069e-55	203.0	COG1402@1|root,COG1402@2|Bacteria,4NF2C@976|Bacteroidetes,47S41@768503|Cytophagia	976|Bacteroidetes	F	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
CMS1_k127_5690941_0	1123242.JH636434_gene5120	2.729e-151	499.0	COG2151@1|root,COG2151@2|Bacteria	2|Bacteria	L	metal-sulfur cluster biosynthetic enzyme	-	-	-	ko:K02612	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FeS_assembly_P
CMS1_k127_5690941_4	1123508.JH636446_gene6317	2.018e-83	289.0	COG3618@1|root,COG3618@2|Bacteria,2IY4K@203682|Planctomycetes	203682|Planctomycetes	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CMS1_k127_5690941_2	1121012.AUKX01000016_gene3001	7.754e-136	445.0	COG0673@1|root,COG0673@2|Bacteria,4NGTW@976|Bacteroidetes,1I164@117743|Flavobacteriia,23IAD@178469|Arenibacter	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_5690941_1	344747.PM8797T_04995	9.754e-141	467.0	COG4145@1|root,COG4145@2|Bacteria,2IYD0@203682|Planctomycetes	203682|Planctomycetes	H	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307,ko:K14392	-	-	-	-	ko00000,ko02000	2.A.21,2.A.21.1	-	-	SSF
CMS1_k127_5690941_7	344747.PM8797T_05000	1.168e-15	80.0	2EK31@1|root,33DTF@2|Bacteria,2J1NA@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF997
CMS1_k127_5690941_8	2423.NA23_0209490	3.865e-11	68.0	arCOG03622@1|root,33HZF@2|Bacteria,2GE37@200918|Thermotogae	200918|Thermotogae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5691874_0	556261.HMPREF0240_03243	7.347e-167	538.0	COG3119@1|root,COG3119@2|Bacteria,1TSUU@1239|Firmicutes,25CDH@186801|Clostridia,36WTZ@31979|Clostridiaceae	186801|Clostridia	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS1_k127_5691874_1	1122214.AQWH01000016_gene1588	3.597e-91	317.0	COG3119@1|root,COG3119@2|Bacteria,1MWY7@1224|Proteobacteria,2TV04@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS1_k127_5692957_0	1238182.C882_3564	1.36e-191	611.0	COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,1MU2Y@1224|Proteobacteria,2TQZ6@28211|Alphaproteobacteria,2JQPR@204441|Rhodospirillales	204441|Rhodospirillales	EQ	Hydantoinase/oxoprolinase N-terminal region	-	-	3.5.2.9	ko:K01469	ko00480,map00480	-	R00251	RC00553	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
CMS1_k127_5692957_2	1244869.H261_02546	2.93e-23	103.0	COG2361@1|root,COG2361@2|Bacteria,1N6ZA@1224|Proteobacteria,2UDXR@28211|Alphaproteobacteria,2JTB8@204441|Rhodospirillales	204441|Rhodospirillales	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
CMS1_k127_5692957_3	479434.Sthe_2362	2.389e-15	79.0	COG1669@1|root,COG1669@2|Bacteria,2G9HE@200795|Chloroflexi	200795|Chloroflexi	L	PFAM DNA polymerase, beta domain protein region	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
CMS1_k127_5692957_1	411154.GFO_3436	4.248e-29	119.0	COG2105@1|root,COG2105@2|Bacteria,4NQXV@976|Bacteroidetes,1I37H@117743|Flavobacteriia	976|Bacteroidetes	S	PFAM AIG2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5706603_2	497964.CfE428DRAFT_3307	1.413e-69	242.0	COG0412@1|root,COG4409@1|root,COG0412@2|Bacteria,COG4409@2|Bacteria,46UD7@74201|Verrucomicrobia	74201|Verrucomicrobia	GQ	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5706603_3	886293.Sinac_1118	1.402e-28	125.0	COG3064@1|root,COG3064@2|Bacteria,2IXYB@203682|Planctomycetes	203682|Planctomycetes	M	YXWGXW repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	YXWGXW
CMS1_k127_5706603_1	1121859.KB890738_gene3329	1.239e-125	419.0	COG3669@1|root,COG3669@2|Bacteria,4NE74@976|Bacteroidetes,47KQM@768503|Cytophagia	976|Bacteroidetes	G	Alpha-L-fucosidase	-	-	-	-	-	-	-	-	-	-	-	-	Alpha_L_fucos
CMS1_k127_5706603_0	344747.PM8797T_27502	2.862e-145	469.0	COG4409@1|root,COG4409@2|Bacteria,2J2E2@203682|Planctomycetes	203682|Planctomycetes	G	Neuraminidase (sialidase)	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
CMS1_k127_5720718_0	525897.Dbac_2556	3.469e-156	527.0	COG1874@1|root,COG1874@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	3.2.1.23,3.2.1.4	ko:K01179,ko:K01190,ko:K12308	ko00052,ko00500,ko00511,ko00600,ko01100,map00052,map00500,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114,R06200,R11307,R11308	RC00049,RC00452	ko00000,ko00001,ko01000	-	GH5,GH9	-	Bac_rhamnosid_C,CBM_6,DUF4832,DUF4978,F5_F8_type_C,FIVAR,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_42,NPCBM,PA,TSP_3
CMS1_k127_5720718_2	1403819.BATR01000092_gene2789	6.662e-129	420.0	COG1577@1|root,COG1577@2|Bacteria,46V85@74201|Verrucomicrobia	74201|Verrucomicrobia	I	mevalonate kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	GHMP_kinases_C,GHMP_kinases_N
CMS1_k127_5720718_5	483219.LILAB_28890	4.957e-44	168.0	COG1595@1|root,COG1595@2|Bacteria,1PEJM@1224|Proteobacteria,4380A@68525|delta/epsilon subdivisions,2X3AB@28221|Deltaproteobacteria,2YV3Y@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_5720718_3	547042.BACCOPRO_00992	3.165e-90	332.0	COG1572@1|root,COG1572@2|Bacteria,4PJMZ@976|Bacteroidetes,2FZ9J@200643|Bacteroidia	976|Bacteroidetes	S	Domain of unknown function (DUF4091)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4091
CMS1_k127_5720718_4	1449126.JQKL01000039_gene1065	9.244e-85	297.0	COG0569@1|root,COG0569@2|Bacteria,1TPNS@1239|Firmicutes,24830@186801|Clostridia,2688V@186813|unclassified Clostridiales	186801|Clostridia	P	TrkA-N domain	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
CMS1_k127_5720718_1	204669.Acid345_2713	6.977e-155	513.0	COG0484@1|root,COG2864@1|root,COG0484@2|Bacteria,COG2864@2|Bacteria,3Y6QW@57723|Acidobacteria	57723|Acidobacteria	C	Prokaryotic cytochrome b561	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Ni_hydr_CYTB
CMS1_k127_5720718_6	1379698.RBG1_1C00001G0777	2.006e-33	137.0	COG2864@1|root,COG2864@2|Bacteria,2NQFM@2323|unclassified Bacteria	2|Bacteria	P	Prokaryotic cytochrome b561	cbcY	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Cytochrome_C7,Ni_hydr_CYTB,Paired_CXXCH_1,Rhodanese
CMS1_k127_5726500_7	504472.Slin_4349	1.627e-33	136.0	COG2010@1|root,COG3291@1|root,COG4625@1|root,COG2010@2|Bacteria,COG3291@2|Bacteria,COG4625@2|Bacteria,4NJDV@976|Bacteroidetes,47NUN@768503|Cytophagia	976|Bacteroidetes	E	PFAM Di-glucose binding within endoplasmic reticulum	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Malectin,NPCBM,PA14,RicinB_lectin_2
CMS1_k127_5726500_0	1242864.D187_001187	2.113e-120	396.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,42NCX@68525|delta/epsilon subdivisions,2WJUZ@28221|Deltaproteobacteria,2YWPA@29|Myxococcales	28221|Deltaproteobacteria	S	ATPase associated with various cellular activities	moxR2	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS1_k127_5726500_3	497964.CfE428DRAFT_4543	3.101e-72	258.0	COG1721@1|root,COG1721@2|Bacteria,46TKV@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CMS1_k127_5726500_2	497964.CfE428DRAFT_4542	5.387e-74	275.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	BatA,CARDB,DUF4091,Glyco_hydro_71,HYR,Hint_2,Peptidase_C11
CMS1_k127_5726500_1	497964.CfE428DRAFT_2093	6.901e-92	329.0	COG2304@1|root,COG2304@2|Bacteria,46UTA@74201|Verrucomicrobia	74201|Verrucomicrobia	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5726500_4	497964.CfE428DRAFT_4534	7.889e-68	261.0	COG1196@1|root,COG1196@2|Bacteria,46TX7@74201|Verrucomicrobia	74201|Verrucomicrobia	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5726500_5	1403819.BATR01000085_gene2461	1.169e-66	234.0	COG1657@1|root,COG1657@2|Bacteria,46TYK@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
CMS1_k127_5726500_6	497964.CfE428DRAFT_4532	3.574e-45	176.0	COG0737@1|root,COG0737@2|Bacteria,46TFI@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
CMS1_k127_5726500_9	268739.Nmlp_1863	4.709e-13	81.0	COG1331@1|root,arCOG02007@2157|Archaea,2XT1C@28890|Euryarchaeota,23SUJ@183963|Halobacteria	183963|Halobacteria	O	COG1331 Highly conserved protein containing a thioredoxin domain	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
CMS1_k127_5726500_8	686340.Metal_0554	1.611e-13	83.0	28HF6@1|root,2Z7RB@2|Bacteria,1P254@1224|Proteobacteria,1S4WK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Alginate export	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp
CMS1_k127_5726500_10	1265505.ATUG01000001_gene4648	6.948e-08	54.0	COG0369@1|root,COG1151@2|Bacteria,1N88B@1224|Proteobacteria,42M2C@68525|delta/epsilon subdivisions,2WIVE@28221|Deltaproteobacteria,2MHVG@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O	hcp	GO:0000302,GO:0003674,GO:0003824,GO:0004601,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016661,GO:0016684,GO:0042221,GO:0042493,GO:0042542,GO:0046677,GO:0050418,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1990748	1.7.99.1	ko:K05601	ko00910,map00910	-	R00143	RC02797	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_2834	Prismane
CMS1_k127_5728856_5	269799.Gmet_2656	4.443e-08	58.0	2EG51@1|root,339WY@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5728856_2	1168034.FH5T_16310	1.895e-36	145.0	COG0526@1|root,COG0526@2|Bacteria,4NW7T@976|Bacteroidetes,2FTAZ@200643|Bacteroidia	976|Bacteroidetes	CO	Antioxidant, AhpC TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
CMS1_k127_5728856_0	1068978.AMETH_1262	1.171e-73	260.0	COG2133@1|root,COG2133@2|Bacteria,2ID9F@201174|Actinobacteria	201174|Actinobacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	SGL
CMS1_k127_5728856_1	518766.Rmar_1330	9.262e-58	210.0	COG1262@1|root,COG1262@2|Bacteria,4NEUZ@976|Bacteroidetes	976|Bacteroidetes	KLT	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2,Big_2,FGE-sulfatase
CMS1_k127_5728856_3	1117314.PCIT_05619	1.078e-15	88.0	COG5295@1|root,COG5295@2|Bacteria,1N8QZ@1224|Proteobacteria	1224|Proteobacteria	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5728856_4	1408473.JHXO01000007_gene862	2.801e-11	65.0	COG0526@1|root,COG0526@2|Bacteria,4NR1K@976|Bacteroidetes,2FS53@200643|Bacteroidia	976|Bacteroidetes	CO	Redoxin family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
CMS1_k127_5742591_4	706587.Desti_3611	7.988e-36	139.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,42MEI@68525|delta/epsilon subdivisions,2WJEG@28221|Deltaproteobacteria,2MRZC@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	TIGRFAM asparagine synthase (glutamine-hydrolyzing)	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
CMS1_k127_5742591_2	1210884.HG799462_gene8051	2.392e-91	311.0	COG1131@1|root,COG1131@2|Bacteria,2IZF2@203682|Planctomycetes	203682|Planctomycetes	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
CMS1_k127_5742591_5	661478.OP10G_2310	2.079e-09	68.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,DUF3526
CMS1_k127_5742591_3	661478.OP10G_2309	8.159e-80	276.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_5742591_1	1379698.RBG1_1C00001G0123	1.274e-112	370.0	COG0053@1|root,COG0053@2|Bacteria,2NPHA@2323|unclassified Bacteria	2|Bacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	fieF	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
CMS1_k127_5742591_0	314230.DSM3645_21809	1.411e-201	636.0	COG0334@1|root,COG0334@2|Bacteria,2IWWC@203682|Planctomycetes	203682|Planctomycetes	C	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
CMS1_k127_5753638_0	1206743.BAGM01000049_gene1214	0.000207	54.0	COG0477@1|root,COG4932@1|root,COG2814@2|Bacteria,COG4932@2|Bacteria,2H8UD@201174|Actinobacteria,4FV1Y@85025|Nocardiaceae	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,MFS_1,Sugar_tr
CMS1_k127_576780_1	497964.CfE428DRAFT_3508	6.682e-87	316.0	COG1621@1|root,COG1621@2|Bacteria,46T0U@74201|Verrucomicrobia	74201|Verrucomicrobia	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_576780_0	1415779.JOMH01000001_gene2508	4.551e-124	405.0	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,1RMR8@1236|Gammaproteobacteria,1X4D1@135614|Xanthomonadales	135614|Xanthomonadales	P	transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
CMS1_k127_576780_4	1121451.DESAM_21374	3.222e-44	179.0	COG1538@1|root,COG1538@2|Bacteria,1PCPQ@1224|Proteobacteria,42PU9@68525|delta/epsilon subdivisions,2WU8U@28221|Deltaproteobacteria,2M8K7@213115|Desulfovibrionales	28221|Deltaproteobacteria	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
CMS1_k127_576780_2	316067.Geob_2520	1.116e-79	273.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,42T7G@68525|delta/epsilon subdivisions,2WKC5@28221|Deltaproteobacteria,43TVM@69541|Desulfuromonadales	28221|Deltaproteobacteria	KT	Domain of unknown function (DUF4118)	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GGDEF,HD,HD_5,dCache_2
CMS1_k127_5779877_11	926550.CLDAP_28350	2.399e-11	69.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Collagen,G5,Gln_amidase,Gram_pos_anchor,YSIRK_signal,YadA_stalk
CMS1_k127_5779877_0	1379698.RBG1_1C00001G1779	4.781e-136	442.0	COG0714@1|root,COG0714@2|Bacteria,2NNMQ@2323|unclassified Bacteria	2|Bacteria	S	ATPase associated with various cellular	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS1_k127_5779877_3	1499967.BAYZ01000069_gene1845	6.26e-104	346.0	COG1721@1|root,COG1721@2|Bacteria,2NNQI@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function DUF58	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF58
CMS1_k127_5779877_12	1144342.PMI40_01466	1.806e-06	59.0	COG0760@1|root,COG0760@2|Bacteria,1R4EF@1224|Proteobacteria,2VK6Z@28216|Betaproteobacteria,474DT@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	TIGRFAM peptidyl-prolyl cis-trans isomerase, EpsD family	epsD	-	-	-	-	-	-	-	-	-	-	-	Rotamase_2,SurA_N_3
CMS1_k127_5779877_8	237368.SCABRO_01881	8.646e-32	136.0	2DQN8@1|root,337RD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5779877_5	237368.SCABRO_01882	1.02e-65	239.0	COG2304@1|root,COG2304@2|Bacteria,2IYWC@203682|Planctomycetes	203682|Planctomycetes	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
CMS1_k127_5779877_6	497964.CfE428DRAFT_3460	1.583e-47	184.0	COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,46SP8@74201|Verrucomicrobia	74201|Verrucomicrobia	J	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
CMS1_k127_5779877_14	1232437.KL661999_gene4710	4.589e-06	58.0	COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,1MW51@1224|Proteobacteria,42M45@68525|delta/epsilon subdivisions,2WM19@28221|Deltaproteobacteria,2MHT6@213118|Desulfobacterales	28221|Deltaproteobacteria	K	PFAM von Willebrand factor type A domain	batB	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,TPR_1,TPR_16,TPR_2,VWA,VWA_2
CMS1_k127_5779877_7	547042.BACCOPRO_01657	1.989e-33	148.0	COG0457@1|root,COG0457@2|Bacteria,4NERG@976|Bacteroidetes,2FMK5@200643|Bacteroidia,4AK7T@815|Bacteroidaceae	976|Bacteroidetes	S	COG NOG06393 non supervised orthologous group	batD	-	-	-	-	-	-	-	-	-	-	-	BatD,TPR_2
CMS1_k127_5779877_9	1121895.Q765_14840	6.675e-20	100.0	COG0457@1|root,COG0457@2|Bacteria,4NF5V@976|Bacteroidetes,1HYKU@117743|Flavobacteriia,2NU4E@237|Flavobacterium	976|Bacteroidetes	T	BatE protein	batE	-	-	-	-	-	-	-	-	-	-	-	SH3_3,SH3_4,TPR_1,TPR_11,TPR_16,TPR_2
CMS1_k127_5779877_1	338966.Ppro_1343	7.293e-123	427.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,42MN5@68525|delta/epsilon subdivisions,2WINN@28221|Deltaproteobacteria,43SYQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,DUF294,GlnD_UR_UTase,GlnE,HD,NTP_transf_2
CMS1_k127_5779877_4	1267535.KB906767_gene3235	1.2e-72	263.0	COG0265@1|root,COG0265@2|Bacteria,3Y2SD@57723|Acidobacteria,2JI16@204432|Acidobacteriia	204432|Acidobacteriia	O	Trypsin	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
CMS1_k127_5779877_10	575540.Isop_2594	6.85e-17	86.0	2DQ4A@1|root,334NN@2|Bacteria,2J0NK@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF2752)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2752
CMS1_k127_5779877_2	1121904.ARBP01000043_gene2130	8.568e-112	388.0	COG3661@1|root,COG3661@2|Bacteria,4PPN5@976|Bacteroidetes	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 67 family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5779877_15	765869.BDW_05125	2.192e-05	52.0	COG0664@1|root,COG0664@2|Bacteria,1QX62@1224|Proteobacteria,42S57@68525|delta/epsilon subdivisions,2MTX3@213481|Bdellovibrionales,2X205@28221|Deltaproteobacteria	213481|Bdellovibrionales	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
CMS1_k127_5779877_13	215803.DB30_8035	1.881e-06	60.0	COG4932@1|root,COG4932@2|Bacteria,1NXIX@1224|Proteobacteria,430KM@68525|delta/epsilon subdivisions,2WVSB@28221|Deltaproteobacteria,2YYGY@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS1_k127_5781734_0	314230.DSM3645_18671	6.935e-86	303.0	COG0591@1|root,COG0591@2|Bacteria,2J2U0@203682|Planctomycetes	203682|Planctomycetes	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
CMS1_k127_5781734_2	1123242.JH636434_gene5498	3.066e-39	162.0	COG0001@1|root,COG0001@2|Bacteria,2IZE0@203682|Planctomycetes	203682|Planctomycetes	H	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2,Aminotran_3
CMS1_k127_5781734_1	880070.Cycma_0137	9.226e-42	157.0	COG0001@1|root,COG3618@1|root,COG0001@2|Bacteria,COG3618@2|Bacteria,4NK3F@976|Bacteroidetes,47NWU@768503|Cytophagia	976|Bacteroidetes	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Amidohydro_2,Aminotran_3
CMS1_k127_5790840_8	629265.PMA4326_05995	1.062e-06	55.0	COG0454@1|root,COG0456@2|Bacteria,1NMEA@1224|Proteobacteria,1T33V@1236|Gammaproteobacteria,1ZA1E@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
CMS1_k127_5790840_7	1463825.JNXC01000004_gene4313	2.945e-07	63.0	2EE91@1|root,3383F@2|Bacteria,2IAWN@201174|Actinobacteria,4EA0R@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5790840_3	1408445.JHXP01000013_gene2487	4.528e-41	158.0	COG1335@1|root,COG1335@2|Bacteria,1MU5N@1224|Proteobacteria,1S7F3@1236|Gammaproteobacteria,1JE9G@118969|Legionellales	118969|Legionellales	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
CMS1_k127_5790840_6	1292035.H476_1041	2.172e-17	89.0	COG1961@1|root,COG1961@2|Bacteria,1TP0S@1239|Firmicutes,24A9P@186801|Clostridia	186801|Clostridia	L	resolvase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
CMS1_k127_5790840_4	243090.RB1862	8.628e-21	98.0	COG1725@1|root,COG1725@2|Bacteria,2J0ST@203682|Planctomycetes	203682|Planctomycetes	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
CMS1_k127_5790840_5	1123065.ATWL01000002_gene1650	1.689e-18	100.0	COG0613@1|root,COG0613@2|Bacteria,2GNPF@201174|Actinobacteria	201174|Actinobacteria	Q	phytanoyl-CoA dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	PHP
CMS1_k127_5790840_1	886293.Sinac_6462	5.386e-109	362.0	COG0451@1|root,COG0451@2|Bacteria,2IX7V@203682|Planctomycetes	203682|Planctomycetes	M	PFAM NAD-dependent epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
CMS1_k127_5790840_2	1463825.JNXC01000003_gene3985	1.321e-53	201.0	COG0710@1|root,COG0710@2|Bacteria,2GREB@201174|Actinobacteria	201174|Actinobacteria	E	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate	aroD	-	4.2.1.10	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_I
CMS1_k127_5790840_0	1121451.DESAM_22028	1.892e-128	433.0	COG1807@1|root,COG1807@2|Bacteria,1QQYT@1224|Proteobacteria,435NZ@68525|delta/epsilon subdivisions,2X02E@28221|Deltaproteobacteria,2M9ZT@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS1_k127_5804229_0	223192.XP_007915956.1	1.213e-144	480.0	COG4030@1|root,2SKR2@2759|Eukaryota,39W5K@33154|Opisthokonta,3NXCY@4751|Fungi,3QPYP@4890|Ascomycota,21CB8@147550|Sordariomycetes	4751|Fungi	S	Protein of unknown function (DUF2961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
CMS1_k127_5807888_4	1499967.BAYZ01000049_gene2752	1.877e-20	102.0	COG3119@1|root,COG3119@2|Bacteria,2NR0Q@2323|unclassified Bacteria	2|Bacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,DUF4976,Sulfatase
CMS1_k127_5807888_5	746697.Aeqsu_1953	5.101e-17	97.0	COG1520@1|root,COG1520@2|Bacteria,4NVQ3@976|Bacteroidetes	976|Bacteroidetes	M	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25,VCBS
CMS1_k127_5807888_3	330214.NIDE2388	6.307e-22	113.0	29R89@1|root,30C9N@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5807888_7	314230.DSM3645_04815	1.47e-13	82.0	COG2165@1|root,COG2165@2|Bacteria,2J1YP@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CMS1_k127_5807888_0	1267535.KB906767_gene3753	5.807e-235	746.0	28J51@1|root,2Z90X@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5807888_2	1957.JODX01000015_gene1362	2.016e-44	175.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_5807888_8	1121439.dsat_2166	3.619e-13	81.0	COG0577@1|root,COG0577@2|Bacteria,1R6DP@1224|Proteobacteria,42PWX@68525|delta/epsilon subdivisions,2WJSB@28221|Deltaproteobacteria,2M949@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS1_k127_5807888_1	344747.PM8797T_32040	1.915e-142	498.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Malectin,PQQ_2,PQQ_3
CMS1_k127_5815679_9	1313421.JHBV01000032_gene1621	4.803e-36	144.0	COG0741@1|root,COG3409@1|root,COG0741@2|Bacteria,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	trwN	-	-	ko:K03194,ko:K07273,ko:K08307,ko:K08309,ko:K12089	ko03070,ko05120,map03070,map05120	M00333,M00564	-	-	ko00000,ko00001,ko00002,ko01000,ko01011,ko02044	3.A.7.12.1	GH23	-	Glyco_hydro_25,PG_binding_1,SLT
CMS1_k127_5815679_5	234267.Acid_7933	1.424e-61	220.0	COG0175@1|root,COG0529@1|root,COG0175@2|Bacteria,COG0529@2|Bacteria,3Y5BG@57723|Acidobacteria	57723|Acidobacteria	F	Catalyzes the synthesis of activated sulfate	cysC	-	1.8.4.10,1.8.4.8,2.7.1.25	ko:K00390,ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R02021,R04928	RC00002,RC00007,RC00078,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
CMS1_k127_5815679_1	926550.CLDAP_18800	1.487e-155	509.0	COG0155@1|root,COG0155@2|Bacteria,2G7ZA@200795|Chloroflexi	200795|Chloroflexi	C	Nitrite and sulphite reductase 4Fe-4S domain	-	-	1.8.7.1	ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00859,R03600	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
CMS1_k127_5815679_2	1499967.BAYZ01000145_gene6204	3.166e-85	286.0	COG0302@1|root,COG0302@2|Bacteria,2NPAT@2323|unclassified Bacteria	2|Bacteria	H	GTP cyclohydrolase I	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
CMS1_k127_5815679_6	1499967.BAYZ01000145_gene6205	3.772e-40	155.0	COG0801@1|root,COG0801@2|Bacteria	2|Bacteria	H	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity	folK	GO:0000287,GO:0003674,GO:0003824,GO:0003848,GO:0005488,GO:0016740,GO:0016772,GO:0016778,GO:0043167,GO:0043169,GO:0046872	2.7.6.3,4.1.2.25	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503,R03504	RC00002,RC00017,RC00721,RC00943	ko00000,ko00001,ko00002,ko01000	-	-	iECDH1ME8569_1439.ECDH1ME8569_0136,iEcDH1_1363.EcDH1_3460,iJN746.PP_4698,iSBO_1134.SBO_0131	FolB,HPPK
CMS1_k127_5815679_7	1499967.BAYZ01000145_gene6206	2.813e-39	150.0	COG1539@1|root,COG1539@2|Bacteria,2NQ1A@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folX	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008719,GO:0009987,GO:0016853,GO:0019752,GO:0034641,GO:0042558,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0071704,GO:1901360,GO:1901564	1.13.11.81,4.1.2.25,5.1.99.7,5.1.99.8	ko:K01633,ko:K07589	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073,R11082	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
CMS1_k127_5815679_4	1499967.BAYZ01000145_gene6207	6.633e-70	245.0	COG1028@1|root,COG1028@2|Bacteria,2NQVU@2323|unclassified Bacteria	2|Bacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.5.1.33	ko:K03793	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
CMS1_k127_5815679_10	1396141.BATP01000032_gene4325	2.822e-31	134.0	COG0265@1|root,COG0265@2|Bacteria,46W40@74201|Verrucomicrobia	74201|Verrucomicrobia	O	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5815679_0	1396141.BATP01000032_gene4324	1.126e-165	544.0	COG0265@1|root,COG0265@2|Bacteria,46SHP@74201|Verrucomicrobia,2IU51@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Trypsin	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
CMS1_k127_5815679_15	391600.ABRU01000041_gene2559	0.0001224	54.0	COG3712@1|root,COG3712@2|Bacteria,1N39R@1224|Proteobacteria,2UBUM@28211|Alphaproteobacteria,2KH1W@204458|Caulobacterales	204458|Caulobacterales	PT	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4880,FecR
CMS1_k127_5815679_12	762948.HMPREF0733_10782	3.905e-20	99.0	COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria,1WA3Q@1268|Micrococcaceae	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_5815679_13	1269813.ATUL01000013_gene264	1.212e-14	78.0	COG5450@1|root,COG5450@2|Bacteria	2|Bacteria	K	positive regulation of growth	-	GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007	-	-	-	-	-	-	-	-	-	-	VapB_antitoxin
CMS1_k127_5815679_8	671143.DAMO_1860	4.245e-36	139.0	COG1487@1|root,COG1487@2|Bacteria	2|Bacteria	S	nuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	PIN
CMS1_k127_5815679_3	1304880.JAGB01000002_gene1921	3.104e-80	280.0	COG1482@1|root,COG1482@2|Bacteria,1V0PH@1239|Firmicutes,2487K@186801|Clostridia	186801|Clostridia	G	mannose-6-phosphate isomerase, class I	manA	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS19425	PMI_typeI
CMS1_k127_5815679_11	469383.Cwoe_3173	5.579e-27	116.0	COG0491@1|root,COG0491@2|Bacteria,2HGYI@201174|Actinobacteria,4CQY2@84995|Rubrobacteria	84995|Rubrobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS1_k127_5821417_0	641524.ADICYQ_0706	2.456e-99	343.0	COG3391@1|root,COG4409@1|root,COG3391@2|Bacteria,COG4409@2|Bacteria,4NX00@976|Bacteroidetes	976|Bacteroidetes	G	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1,Lactonase
CMS1_k127_5821417_1	1123242.JH636435_gene1206	2.848e-30	137.0	COG3291@1|root,COG3291@2|Bacteria,2J3CN@203682|Planctomycetes	203682|Planctomycetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5823307_3	316067.Geob_2506	2.543e-26	109.0	COG1168@1|root,COG1168@2|Bacteria,1MY33@1224|Proteobacteria,42M6F@68525|delta/epsilon subdivisions,2WK37@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM aminotransferase class I and II	-	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS1_k127_5823307_4	247490.KSU1_B0315	0.000456	50.0	COG5588@1|root,COG5588@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1326
CMS1_k127_5823307_2	1379698.RBG1_1C00001G0915	7.64e-38	155.0	2DF7D@1|root,32U4V@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SEC-C
CMS1_k127_5823307_0	344747.PM8797T_15161	2.73e-105	365.0	COG0673@1|root,COG0673@2|Bacteria,2IXE4@203682|Planctomycetes	203682|Planctomycetes	S	and related	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_5823307_1	1123508.JH636440_gene2112	5.986e-80	277.0	COG1262@1|root,COG1262@2|Bacteria,2IYGB@203682|Planctomycetes	203682|Planctomycetes	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
CMS1_k127_5824414_4	935948.KE386494_gene320	1.201e-18	85.0	COG0407@1|root,COG0407@2|Bacteria,1UZSW@1239|Firmicutes,24E13@186801|Clostridia,42IBM@68295|Thermoanaerobacterales	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
CMS1_k127_5824414_2	1232453.BAIF02000054_gene1201	7.907e-122	401.0	COG0407@1|root,COG0407@2|Bacteria,1V4YU@1239|Firmicutes,24KSS@186801|Clostridia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
CMS1_k127_5824414_0	509635.N824_10105	2.3e-161	526.0	COG4146@1|root,COG4146@2|Bacteria,4NE9S@976|Bacteroidetes,1IQDG@117747|Sphingobacteriia	976|Bacteroidetes	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
CMS1_k127_5824414_1	1449063.JMLS01000017_gene632	1.546e-150	487.0	COG4948@1|root,COG4948@2|Bacteria,1TZ0E@1239|Firmicutes,4HDTT@91061|Bacilli,26VX8@186822|Paenibacillaceae	91061|Bacilli	M	Belongs to the mandelate racemase muconate lactonizing enzyme family	yitF	-	5.5.1.27	ko:K18983	ko00053,map00053	-	R10847	RC03287	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
CMS1_k127_5824414_5	633147.Olsu_1249	9.723e-10	70.0	COG0524@1|root,COG0524@2|Bacteria,2GKBG@201174|Actinobacteria,4CX0Y@84998|Coriobacteriia	84998|Coriobacteriia	G	pfkB family carbohydrate kinase	-	-	2.7.1.20	ko:K00856	ko00230,ko01100,map00230,map01100	-	R00185	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
CMS1_k127_5824414_6	270374.MELB17_03180	0.0001427	48.0	COG1637@1|root,COG3680@1|root,COG1637@2|Bacteria,COG3680@2|Bacteria,1R7PZ@1224|Proteobacteria	1224|Proteobacteria	L	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures	-	-	-	ko:K09968	-	-	-	-	ko00000	-	-	-	-
CMS1_k127_5824414_3	335543.Sfum_2320	3.321e-72	250.0	COG2249@1|root,COG2249@2|Bacteria,1RA5X@1224|Proteobacteria,42R0Z@68525|delta/epsilon subdivisions,2WMNE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM NAD(P)H dehydrogenase (quinone)	-	-	1.6.5.2	ko:K00355	ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	Flavodoxin_2
CMS1_k127_5824870_1	1403819.BATR01000162_gene5451	9.664e-66	236.0	COG1333@1|root,COG1333@2|Bacteria,46SUY@74201|Verrucomicrobia,2IUGM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	ResB-like family	-	-	-	-	-	-	-	-	-	-	-	-	ResB
CMS1_k127_5824870_0	1396141.BATP01000016_gene2844	1.055e-105	369.0	COG0755@1|root,COG0755@2|Bacteria,46VBM@74201|Verrucomicrobia,2IU24@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Cytochrome C assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
CMS1_k127_5826005_0	742766.HMPREF9455_01596	1.233e-84	287.0	COG4692@1|root,COG4692@2|Bacteria,4NEYM@976|Bacteroidetes,2FQDF@200643|Bacteroidia,230Y5@171551|Porphyromonadaceae	976|Bacteroidetes	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
CMS1_k127_5826005_1	616991.JPOO01000001_gene4017	1.388e-31	141.0	COG4692@1|root,COG4692@2|Bacteria,4NEYM@976|Bacteroidetes,1IIH8@117743|Flavobacteriia,23G2P@178469|Arenibacter	976|Bacteroidetes	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
CMS1_k127_5827459_1	556261.HMPREF0240_03594	1.779e-07	59.0	COG0407@1|root,COG0407@2|Bacteria,1UZD2@1239|Firmicutes,24C43@186801|Clostridia,36H7R@31979|Clostridiaceae	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
CMS1_k127_5827459_0	1288963.ADIS_1157	3.257e-262	830.0	COG3292@1|root,COG3292@2|Bacteria,4P1XS@976|Bacteroidetes,47U9C@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5832223_2	1046714.AMRX01000006_gene2995	1.947e-37	151.0	COG1874@1|root,COG1874@2|Bacteria,1R702@1224|Proteobacteria,1RUC4@1236|Gammaproteobacteria,46A38@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_42
CMS1_k127_5832223_0	1232449.BAHV02000008_gene670	1.577e-100	340.0	COG0176@1|root,COG0176@2|Bacteria,1U9RA@1239|Firmicutes,24DCI@186801|Clostridia	186801|Clostridia	H	PFAM Transaldolase	-	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
CMS1_k127_5832223_1	935567.JAES01000065_gene2346	2.841e-96	330.0	COG3464@1|root,COG3464@2|Bacteria,1N2V1@1224|Proteobacteria,1SZGW@1236|Gammaproteobacteria,1XCV1@135614|Xanthomonadales	135614|Xanthomonadales	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
CMS1_k127_5837080_1	1453505.JASY01000006_gene1259	9.814e-07	61.0	COG3866@1|root,COG3866@2|Bacteria,4P09P@976|Bacteroidetes,1I0G9@117743|Flavobacteriia,2NTFA@237|Flavobacterium	976|Bacteroidetes	G	Pectate lyase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5837080_0	227882.SAV_1842	8.988e-11	68.0	COG4409@1|root,COG4409@2|Bacteria,2I0CJ@201174|Actinobacteria	201174|Actinobacteria	G	BNR Asp-box repeat	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,Laminin_G_3
CMS1_k127_5842829_6	392499.Swit_3384	3.167e-05	49.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,2K2HE@204457|Sphingomonadales	204457|Sphingomonadales	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
CMS1_k127_5842829_2	661478.OP10G_2798	1.342e-137	457.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
CMS1_k127_5842829_5	521096.Tpau_1655	1.549e-18	88.0	COG2105@1|root,COG2105@2|Bacteria,2IC9E@201174|Actinobacteria	201174|Actinobacteria	E	Gamma-glutamyl cyclotransferase, AIG2-like	-	-	-	-	-	-	-	-	-	-	-	-	GGACT,Lipase_GDSL_2
CMS1_k127_5842829_3	861299.J421_4119	8.113e-102	349.0	COG0534@1|root,COG0534@2|Bacteria,1ZT8D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
CMS1_k127_5842829_0	1499967.BAYZ01000016_gene6513	1.03e-292	920.0	COG0188@1|root,COG0188@2|Bacteria,2NNNR@2323|unclassified Bacteria	2|Bacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
CMS1_k127_5842829_1	648996.Theam_1188	4.469e-256	812.0	COG0187@1|root,COG0187@2|Bacteria,2G3N9@200783|Aquificae	200783|Aquificae	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008150,GO:0008152,GO:0009295,GO:0009330,GO:0009987,GO:0016043,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
CMS1_k127_5842829_7	338966.Ppro_1102	0.0001924	49.0	COG5512@1|root,COG5512@2|Bacteria,1N6KK@1224|Proteobacteria,42TK4@68525|delta/epsilon subdivisions,2WQQS@28221|Deltaproteobacteria,43VF7@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
CMS1_k127_5842829_4	1111479.AXAR01000002_gene2030	5.253e-75	265.0	COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,4HA0W@91061|Bacilli,277VW@186823|Alicyclobacillaceae	91061|Bacilli	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
CMS1_k127_5864919_0	765914.ThisiDRAFT_1231	7.459e-217	679.0	COG0369@1|root,COG1151@2|Bacteria,1N88B@1224|Proteobacteria,1RP1I@1236|Gammaproteobacteria,1WWDV@135613|Chromatiales	135613|Chromatiales	C	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O	hcp	-	1.7.99.1	ko:K05601	ko00910,map00910	-	R00143	RC02797	ko00000,ko00001,ko01000	-	-	-	Prismane
CMS1_k127_5865241_0	596151.DesfrDRAFT_1026	7.174e-123	407.0	COG0535@1|root,COG0535@2|Bacteria,1PC3W@1224|Proteobacteria,436K4@68525|delta/epsilon subdivisions,2X171@28221|Deltaproteobacteria,2MEDF@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
CMS1_k127_5870189_2	313628.LNTAR_08246	7.159e-14	74.0	COG3363@1|root,COG3363@2|Bacteria	2|Bacteria	F	IMP cyclohydrolase activity	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	IMP_cyclohyd
CMS1_k127_5870189_0	290397.Adeh_0291	1.613e-169	547.0	COG0464@1|root,COG0464@2|Bacteria,1MW4T@1224|Proteobacteria,42MBU@68525|delta/epsilon subdivisions,2WIJP@28221|Deltaproteobacteria,2YWW6@29|Myxococcales	28221|Deltaproteobacteria	O	ATPase family associated with various cellular activities (AAA)	-	-	3.6.4.6	ko:K06027	ko04138,ko04721,ko04727,ko04962,map04138,map04721,map04727,map04962	-	-	-	ko00000,ko00001,ko01000,ko04131	1.F.1.1	-	-	AAA
CMS1_k127_5870189_3	368407.Memar_0384	0.0001416	53.0	COG0457@1|root,arCOG03032@2157|Archaea,2Y7M7@28890|Euryarchaeota	28890|Euryarchaeota	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_6,TPR_8
CMS1_k127_5870189_1	1291050.JAGE01000002_gene3793	1.853e-151	487.0	COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,2485N@186801|Clostridia,3WG9P@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
CMS1_k127_5878122_0	1123242.JH636435_gene2024	6.999e-148	504.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXZY@203682|Planctomycetes	203682|Planctomycetes	T	COG0515 Serine threonine protein	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_10,TPR_12,TPR_8,WD40
CMS1_k127_5878691_2	204669.Acid345_2219	3.365e-41	156.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,3Y9GC@57723|Acidobacteria,2JKTW@204432|Acidobacteriia	204432|Acidobacteriia	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
CMS1_k127_5878691_0	1282876.BAOK01000001_gene3037	1.963e-209	661.0	COG0318@1|root,COG0318@2|Bacteria,1MUIC@1224|Proteobacteria,2TUFX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	6.2.1.7	ko:K15868	ko00121,map00121	-	-	-	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
CMS1_k127_5878691_1	1111728.ATYS01000005_gene973	2.885e-138	458.0	COG3119@1|root,COG3119@2|Bacteria,1MV0B@1224|Proteobacteria,1RMSX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Sulfatase	Z012_03425	-	3.1.6.14	ko:K01137,ko:K01138	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00078,M00079	R07808,R07819	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Sulfatase,TAT_signal
CMS1_k127_5878691_3	604354.TSIB_0372	1.143e-22	113.0	COG2407@1|root,arCOG01772@2157|Archaea,2Y2JG@28890|Euryarchaeota,243J3@183968|Thermococci	183968|Thermococci	G	L-fucose isomerase and related	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5883101_5	1122947.FR7_3481	5.349e-24	116.0	COG0860@1|root,COG0860@2|Bacteria,1TR6H@1239|Firmicutes,4H3UN@909932|Negativicutes	909932|Negativicutes	M	PFAM cell wall hydrolase autolysin	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
CMS1_k127_5883101_0	1396418.BATQ01000163_gene1972	1.812e-128	421.0	COG2115@1|root,COG2115@2|Bacteria	2|Bacteria	G	xylose isomerase activity	-	-	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
CMS1_k127_5883101_1	96561.Dole_1918	2.872e-84	288.0	COG1028@1|root,COG1028@2|Bacteria,1MWGC@1224|Proteobacteria,42QH3@68525|delta/epsilon subdivisions,2WKXH@28221|Deltaproteobacteria,2MJC1@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS1_k127_5883101_2	644282.Deba_1707	8.798e-72	252.0	COG1250@1|root,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42M6J@68525|delta/epsilon subdivisions,2WJZQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM 3-hydroxyacyl-CoA dehydrogenase	mmgB	-	1.1.1.157,1.1.1.35,4.2.1.17	ko:K00074,ko:K15016	ko00360,ko00362,ko00650,ko00720,ko01100,ko01120,ko01200,map00360,map00362,map00650,map00720,map01100,map01120,map01200	M00374,M00375	R01975,R01976,R03026,R05576,R06941	RC00029,RC00117,RC00831	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2269	3HCDH,3HCDH_N
CMS1_k127_5883101_6	134676.ACPL_3289	2.413e-16	88.0	COG1011@1|root,COG1011@2|Bacteria,2GNSS@201174|Actinobacteria,4DF7T@85008|Micromonosporales	201174|Actinobacteria	S	HAD-hyrolase-like	-	-	3.1.3.102,3.1.3.104	ko:K07025,ko:K20862	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00548,R07280	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD_2
CMS1_k127_5883101_4	1246459.KB898361_gene5496	6.398e-27	121.0	COG2365@1|root,COG2365@2|Bacteria,1RJ2P@1224|Proteobacteria,2UB4E@28211|Alphaproteobacteria,4BEN0@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Protein tyrosine serine phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Y_phosphatase3
CMS1_k127_5883101_3	1519464.HY22_02615	1.974e-48	190.0	COG2120@1|root,COG2120@2|Bacteria,1FEW5@1090|Chlorobi	1090|Chlorobi	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
CMS1_k127_5883686_0	1499967.BAYZ01000153_gene1551	0.0	1238.0	COG2373@1|root,COG2373@2|Bacteria	2|Bacteria	U	Large extracellular alpha-helical protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,A2M_comp,A2M_recep,CarboxypepD_reg,Plug,Thiol-ester_cl
CMS1_k127_5883686_3	760568.Desku_1774	5.022e-15	80.0	COG1886@1|root,COG1886@2|Bacteria,1TPT8@1239|Firmicutes,24821@186801|Clostridia,26333@186807|Peptococcaceae	186801|Clostridia	N	PFAM Surface presentation of	-	-	-	ko:K02417	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FliMN_C
CMS1_k127_5883686_2	622312.ROSEINA2194_00958	1.09e-28	126.0	COG1360@1|root,COG1360@2|Bacteria,1V8KE@1239|Firmicutes,24GQQ@186801|Clostridia	186801|Clostridia	N	PFAM OmpA MotB domain protein	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
CMS1_k127_5883686_1	555079.Toce_1106	3.167e-83	282.0	COG1291@1|root,COG1291@2|Bacteria,1TRH1@1239|Firmicutes,24AEJ@186801|Clostridia,42FK8@68295|Thermoanaerobacterales	186801|Clostridia	U	PFAM MotA TolQ ExbB proton channel	motA	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
CMS1_k127_5906733_0	1123487.KB892865_gene1503	4.424e-64	231.0	COG0673@1|root,COG0673@2|Bacteria,1MXUP@1224|Proteobacteria,2VIRJ@28216|Betaproteobacteria,2KYJV@206389|Rhodocyclales	206389|Rhodocyclales	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	1.1.1.312	ko:K10219	ko00350,ko00362,ko00627,ko01120,ko01220,map00350,map00362,map00627,map01120,map01220	M00533	R04278,R04279,R04418,R04419	RC00251,RC00254	ko00000,ko00001,ko00002,ko01000	-	-	-	GFO_IDH_MocA
CMS1_k127_5906733_1	266117.Rxyl_2901	9.012e-18	90.0	COG1268@1|root,COG1268@2|Bacteria,2GJ53@201174|Actinobacteria,4CQTM@84995|Rubrobacteria	84995|Rubrobacteria	S	BioY family	-	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
CMS1_k127_5908072_0	1131269.AQVV01000008_gene945	2.351e-95	322.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	ko:K13318,ko:K13322,ko:K16439,ko:K19857	ko00523,ko01055,ko01130,map00523,map01055,map01130	M00798,M00799,M00800	R06436,R06629,R11042,R11047	RC00182,RC00261	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
CMS1_k127_5908072_2	871968.DESME_05410	3.197e-13	75.0	COG4929@1|root,COG4929@2|Bacteria,1UPRT@1239|Firmicutes,24NGM@186801|Clostridia	186801|Clostridia	S	GDYXXLXY protein	-	-	-	-	-	-	-	-	-	-	-	-	GDYXXLXY
CMS1_k127_5908072_3	1123288.SOV_4c03170	1.105e-07	55.0	COG4872@1|root,COG4872@2|Bacteria,1V02I@1239|Firmicutes,4H542@909932|Negativicutes	909932|Negativicutes	S	Predicted membrane protein (DUF2157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2157
CMS1_k127_5908072_1	204669.Acid345_3772	9.133e-14	72.0	COG4968@1|root,COG4968@2|Bacteria,3Y98E@57723|Acidobacteria,2JP4Y@204432|Acidobacteriia	57723|Acidobacteria	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
CMS1_k127_5916726_8	1211813.CAPH01000009_gene257	2.244e-21	104.0	COG3345@1|root,COG3345@2|Bacteria,4NZUR@976|Bacteroidetes,2FNUD@200643|Bacteroidia	976|Bacteroidetes	G	Melibiase	-	-	-	-	-	-	-	-	-	-	-	-	Melibiase
CMS1_k127_5916726_0	1123242.JH636436_gene531	1.453e-144	477.0	COG1225@1|root,COG4409@1|root,COG4692@1|root,COG1225@2|Bacteria,COG4409@2|Bacteria,COG4692@2|Bacteria,2J06F@203682|Planctomycetes	203682|Planctomycetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
CMS1_k127_5916726_5	1479237.JMLY01000001_gene3242	8.376e-45	168.0	COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,1S65E@1236|Gammaproteobacteria,4681I@72275|Alteromonadaceae	1236|Gammaproteobacteria	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
CMS1_k127_5916726_4	1122917.KB899661_gene1194	3.395e-48	186.0	COG0329@1|root,COG0329@2|Bacteria,1TPVS@1239|Firmicutes,4HATJ@91061|Bacilli,274TH@186822|Paenibacillaceae	91061|Bacilli	EM	Belongs to the DapA family	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
CMS1_k127_5916726_7	522772.Dacet_2213	2.499e-25	113.0	COG1694@1|root,COG3956@2|Bacteria,2GF4N@200930|Deferribacteres	200930|Deferribacteres	S	Phosphoribosyl-ATP pyrophosphohydrolase	-	-	-	ko:K02499	-	-	-	-	ko00000,ko03036	-	-	-	MazG
CMS1_k127_5916726_1	1120950.KB892747_gene3702	1.195e-138	462.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	GxGYxYP_C,GxGYxYP_N
CMS1_k127_5916726_3	1380390.JIAT01000009_gene1067	3.61e-59	218.0	COG0673@1|root,COG0673@2|Bacteria,2I9W2@201174|Actinobacteria	201174|Actinobacteria	S	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_5916726_6	1128421.JAGA01000003_gene3091	8.091e-27	128.0	COG4485@1|root,COG4485@2|Bacteria,2NP78@2323|unclassified Bacteria	2|Bacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
CMS1_k127_5916726_2	1303518.CCALI_02763	4.097e-88	302.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_5918117_3	82654.Pse7367_1858	3.112e-93	333.0	COG2931@1|root,COG2931@2|Bacteria,1G3DW@1117|Cyanobacteria,1HAZM@1150|Oscillatoriales	1117|Cyanobacteria	Q	Domain of unknown function (DUF4347)	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4114,DUF4347,HemolysinCabind
CMS1_k127_5918117_13	1347369.CCAD010000007_gene2358	6.093e-26	110.0	COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,4HKH3@91061|Bacilli,1ZGZI@1386|Bacillus	91061|Bacilli	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	yaaK	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
CMS1_k127_5918117_7	742738.HMPREF9460_01545	7.811e-81	280.0	COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,248ED@186801|Clostridia,268H5@186813|unclassified Clostridiales	186801|Clostridia	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
CMS1_k127_5918117_4	1200557.JHWV01000010_gene942	6.52e-83	291.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1TP3N@1239|Firmicutes,4H2D1@909932|Negativicutes	909932|Negativicutes	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	sun	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
CMS1_k127_5918117_16	469371.Tbis_1337	5.815e-08	64.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4DXBC@85010|Pseudonocardiales	201174|Actinobacteria	KLT	serine threonine protein kinase	pknL	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
CMS1_k127_5918117_8	420324.KI911996_gene7838	3.727e-76	260.0	COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,2TQKR@28211|Alphaproteobacteria,1JSYF@119045|Methylobacteriaceae	28211|Alphaproteobacteria	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
CMS1_k127_5918117_10	398511.BpOF4_14820	1.153e-57	216.0	COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,4HBCE@91061|Bacilli,1ZB0W@1386|Bacillus	91061|Bacilli	M	Belongs to the peptidase S11 family	dacF	GO:0003674,GO:0003824,GO:0004175,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
CMS1_k127_5918117_9	118168.MC7420_1035	1.193e-58	231.0	COG0642@1|root,COG2202@1|root,COG3605@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3605@2|Bacteria,COG5002@2|Bacteria,1G09B@1117|Cyanobacteria,1H71H@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
CMS1_k127_5918117_11	314278.NB231_01753	5.376e-57	202.0	COG0328@1|root,COG0328@2|Bacteria,1RCZ1@1224|Proteobacteria,1S3YC@1236|Gammaproteobacteria,1WYRV@135613|Chromatiales	135613|Chromatiales	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
CMS1_k127_5918117_14	671065.MetMK1DRAFT_00016260	6.699e-20	96.0	COG0666@1|root,arCOG04004@2157|Archaea,2XS0N@28889|Crenarchaeota	28889|Crenarchaeota	S	ankyrin repeats	-	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank_2,Ank_4
CMS1_k127_5918117_5	234267.Acid_6178	1.188e-81	283.0	COG1879@1|root,COG1879@2|Bacteria	2|Bacteria	G	ABC-type sugar transport system periplasmic component	ytfQ	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
CMS1_k127_5918117_6	234267.Acid_6177	3.161e-81	280.0	COG1172@1|root,COG1172@2|Bacteria,3Y5DG@57723|Acidobacteria	57723|Acidobacteria	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
CMS1_k127_5918117_12	886293.Sinac_5104	3.33e-34	142.0	COG3468@1|root,COG3468@2|Bacteria,2J1BR@203682|Planctomycetes	203682|Planctomycetes	MU	outer membrane autotransporter barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5918117_1	768670.Calni_0490	5.731e-161	529.0	COG0119@1|root,COG0119@2|Bacteria,2GF3Q@200930|Deferribacteres	200930|Deferribacteres	H	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
CMS1_k127_5918117_0	1123277.KB893185_gene3055	0.0	1501.0	COG4284@1|root,COG4284@2|Bacteria,4PNAA@976|Bacteroidetes,47P1V@768503|Cytophagia	976|Bacteroidetes	G	UTP--glucose-1-phosphate uridylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	UDPGP
CMS1_k127_5918117_2	504472.Slin_2596	1.544e-126	411.0	COG1210@1|root,COG1210@2|Bacteria,4NF1P@976|Bacteroidetes,47NPD@768503|Cytophagia	976|Bacteroidetes	M	Nucleotidyl transferase	-	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
CMS1_k127_5918117_15	391625.PPSIR1_39800	1.014e-13	85.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS1_k127_5918117_17	383372.Rcas_2670	6.948e-07	63.0	COG1306@1|root,COG1306@2|Bacteria,2G81Y@200795|Chloroflexi,374TT@32061|Chloroflexia	32061|Chloroflexia	M	Putative glycosyl hydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,DUF4015
CMS1_k127_5920277_1	1123368.AUIS01000006_gene587	1.41e-132	431.0	COG2957@1|root,COG2957@2|Bacteria,1MX65@1224|Proteobacteria,1RMF1@1236|Gammaproteobacteria,2NCHY@225057|Acidithiobacillales	225057|Acidithiobacillales	E	Belongs to the agmatine deiminase family	-	-	-	-	-	-	-	-	-	-	-	-	PAD_porph
CMS1_k127_5920277_0	243231.GSU1027	6.007e-138	445.0	COG0388@1|root,COG0388@2|Bacteria,1MXG5@1224|Proteobacteria,42M1Y@68525|delta/epsilon subdivisions,2WIPE@28221|Deltaproteobacteria,43T7K@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Carbon-nitrogen hydrolase	aguB	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
CMS1_k127_5920277_2	502025.Hoch_4826	4.402e-88	304.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42NES@68525|delta/epsilon subdivisions,2WJ0V@28221|Deltaproteobacteria,2YU38@29|Myxococcales	28221|Deltaproteobacteria	NU	Type II secretion system (T2SS), protein F	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
CMS1_k127_5920277_4	1121904.ARBP01000008_gene3222	1.713e-05	58.0	COG1621@1|root,COG1621@2|Bacteria,4NG4M@976|Bacteroidetes,47TNW@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolases family 43	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
CMS1_k127_5920277_3	56780.SYN_02573	1.022e-25	110.0	COG3825@1|root,COG3825@2|Bacteria,1MUAJ@1224|Proteobacteria,42N7R@68525|delta/epsilon subdivisions,2WJBI@28221|Deltaproteobacteria,2MR3A@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	VWA containing CoxE family protein	-	-	-	ko:K09989	-	-	-	-	ko00000	-	-	-	VWA_CoxE
CMS1_k127_5922773_0	1396418.BATQ01000078_gene616	8.673e-41	169.0	COG1621@1|root,COG1621@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 32 family	-	-	3.1.3.6,3.1.4.16	ko:K01119	ko00230,ko00240,map00230,map00240	-	R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135	RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	SLH
CMS1_k127_5922773_1	240016.ABIZ01000001_gene4018	1.705e-40	160.0	COG1621@1|root,COG4409@1|root,COG1621@2|Bacteria,COG4409@2|Bacteria,46U32@74201|Verrucomicrobia	74201|Verrucomicrobia	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
CMS1_k127_5924913_4	1121859.KB890739_gene2278	4.807e-11	75.0	COG1409@1|root,COG1520@1|root,COG1409@2|Bacteria,COG1520@2|Bacteria,4NFA9@976|Bacteroidetes,47N9T@768503|Cytophagia	976|Bacteroidetes	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,PQQ_2,PQQ_3
CMS1_k127_5924913_2	502025.Hoch_6416	1.6e-15	88.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,42PHP@68525|delta/epsilon subdivisions,2WIXN@28221|Deltaproteobacteria,2YU93@29|Myxococcales	28221|Deltaproteobacteria	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
CMS1_k127_5924913_5	504472.Slin_6131	1.148e-06	60.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NHS5@976|Bacteroidetes,47MWY@768503|Cytophagia	976|Bacteroidetes	EU	Peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
CMS1_k127_5924913_3	562743.JH976436_gene2492	4.525e-14	77.0	COG3877@1|root,COG3877@2|Bacteria,1VGSH@1239|Firmicutes,4HQ68@91061|Bacilli	91061|Bacilli	S	Protein of unknown function (DUF2089)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2089
CMS1_k127_5924913_0	864702.OsccyDRAFT_0072	5.916e-72	254.0	COG5263@1|root,COG5263@2|Bacteria,1G1AI@1117|Cyanobacteria,1HASA@1150|Oscillatoriales	1117|Cyanobacteria	S	KWG Leptospira	-	-	-	-	-	-	-	-	-	-	-	-	SLH,WG_beta_rep
CMS1_k127_5946293_0	1121468.AUBR01000001_gene579	2.276e-185	588.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia,42FA0@68295|Thermoanaerobacterales	186801|Clostridia	E	amino acid carrier protein	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
CMS1_k127_5946293_1	1121430.JMLG01000002_gene1131	9.927e-59	216.0	COG0500@1|root,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	-	-	2.1.1.302	ko:K21377	-	-	-	-	ko00000,ko01000	-	-	-	Dimerisation2,Methyltransf_2
CMS1_k127_5946293_2	641524.ADICYQ_3837	1.674e-23	117.0	28MHM@1|root,2ZAUH@2|Bacteria,4NKMG@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5954373_3	330214.NIDE2388	2.694e-24	120.0	29R89@1|root,30C9N@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5954373_2	644282.Deba_2158	6.607e-39	162.0	COG4753@1|root,COG5002@1|root,COG4753@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,42QJF@68525|delta/epsilon subdivisions,2WJ9D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,Response_reg
CMS1_k127_5954373_0	945713.IALB_1007	3.061e-174	580.0	COG0383@1|root,COG0383@2|Bacteria	2|Bacteria	G	mannose metabolic process	mngB	GO:0003674,GO:0003824,GO:0004553,GO:0004559,GO:0005975,GO:0005996,GO:0006013,GO:0006464,GO:0006517,GO:0006807,GO:0008150,GO:0008152,GO:0009100,GO:0009987,GO:0015923,GO:0016787,GO:0016798,GO:0019318,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0071704,GO:1901135,GO:1901564	3.2.1.170,3.2.1.24	ko:K01191,ko:K15524	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	iEcolC_1368.EcolC_2924,iSF_1195.SF0565,iSFxv_1172.SFxv_0623,iS_1188.S0578	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
CMS1_k127_5954373_1	1195236.CTER_4163	1.587e-138	445.0	COG0637@1|root,COG0637@2|Bacteria,1VSTY@1239|Firmicutes,24Z1J@186801|Clostridia	186801|Clostridia	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
CMS1_k127_5974164_1	351016.RAZWK3B_10797	1.984e-11	66.0	2EBNQ@1|root,32VM1@2|Bacteria,1N08H@1224|Proteobacteria,2UC9X@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5974164_0	555779.Dthio_PD2105	8.496e-140	450.0	COG3677@1|root,COG3677@2|Bacteria,1MXYX@1224|Proteobacteria,43B03@68525|delta/epsilon subdivisions,2X6E6@28221|Deltaproteobacteria,2MH1Y@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	Transposase zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
CMS1_k127_5979582_0	1123242.JH636434_gene5158	1.045e-101	342.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2
CMS1_k127_5979582_3	338969.Rfer_3144	6.682e-32	133.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_5979582_5	869210.Marky_0947	1.657e-05	55.0	COG1082@1|root,COG1082@2|Bacteria,1WJN9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	PFAM Xylose isomerase-like TIM barrel	-	-	4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
CMS1_k127_5979582_4	1304876.AZVC01000013_gene2683	4.378e-17	93.0	COG0673@1|root,COG0673@2|Bacteria,2GM7J@201174|Actinobacteria	201174|Actinobacteria	K	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_5979582_2	556261.HMPREF0240_03868	4.416e-61	225.0	COG0407@1|root,COG0407@2|Bacteria,1VSHN@1239|Firmicutes,24FDR@186801|Clostridia,36P6Q@31979|Clostridiaceae	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
CMS1_k127_5979582_1	1226325.HMPREF1548_05284	1.154e-81	291.0	COG3119@1|root,COG3119@2|Bacteria,1TQEP@1239|Firmicutes,2482B@186801|Clostridia	186801|Clostridia	P	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS1_k127_5985076_1	1123008.KB905702_gene2354	6.133e-17	87.0	COG3728@1|root,COG3728@2|Bacteria,4NYU7@976|Bacteroidetes,2FU42@200643|Bacteroidia,230YD@171551|Porphyromonadaceae	976|Bacteroidetes	L	Terminase small subunit	-	-	-	ko:K07474	-	-	-	-	ko00000	-	-	-	Terminase_2
CMS1_k127_5985076_0	545695.TREAZ_2560	6.866e-39	162.0	COG1882@1|root,COG1882@2|Bacteria,2J6MA@203691|Spirochaetes	203691|Spirochaetes	H	formate C-acetyltransferase	-	-	2.3.1.54	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
CMS1_k127_5990573_3	370438.PTH_1825	0.0009642	46.0	COG0762@1|root,COG0762@2|Bacteria,1URMB@1239|Firmicutes,24RBP@186801|Clostridia,2633K@186807|Peptococcaceae	186801|Clostridia	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
CMS1_k127_5990573_1	521011.Mpal_0318	4.964e-62	223.0	COG2518@1|root,arCOG00976@2157|Archaea,2XTRM@28890|Euryarchaeota,2N9U4@224756|Methanomicrobia	224756|Methanomicrobia	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
CMS1_k127_5990573_2	28444.JODQ01000007_gene5248	2.083e-14	78.0	COG1725@1|root,COG1725@2|Bacteria,2IHTD@201174|Actinobacteria,4EK05@85012|Streptosporangiales	201174|Actinobacteria	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
CMS1_k127_5990573_0	118166.JH976537_gene2419	2.016e-66	233.0	28NY3@1|root,2ZBVC@2|Bacteria,1G5MR@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5993344_4	575540.Isop_2232	4.161e-86	291.0	COG1131@1|root,COG1131@2|Bacteria,2IYTF@203682|Planctomycetes	2|Bacteria	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_5993344_1	344747.PM8797T_21913	5.083e-128	425.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CMS1_k127_5993344_5	555779.Dthio_PD1816	2.246e-67	239.0	COG1073@1|root,COG1073@2|Bacteria,1RIWI@1224|Proteobacteria,42TGK@68525|delta/epsilon subdivisions,2WNGS@28221|Deltaproteobacteria,2MGTS@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Hydrolase_4
CMS1_k127_5993344_0	1499967.BAYZ01000069_gene1903	1.708e-190	606.0	COG1350@1|root,COG1350@2|Bacteria,2NNY3@2323|unclassified Bacteria	2|Bacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696,ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS1_k127_5993344_6	583355.Caka_0685	1.583e-13	81.0	2BY38@1|root,31PAJ@2|Bacteria,46XWB@74201|Verrucomicrobia,3K8GH@414999|Opitutae	414999|Opitutae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5993344_3	1232453.BAIF02000062_gene1885	8.648e-89	298.0	COG0235@1|root,COG0235@2|Bacteria,1TPDV@1239|Firmicutes,248KI@186801|Clostridia	186801|Clostridia	G	L-ribulose-5-phosphate 4-epimerase	-	-	5.1.3.4	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R05850	RC01479	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
CMS1_k127_5993344_2	880073.Calab_0661	3.146e-115	379.0	COG0042@1|root,COG0042@2|Bacteria,2NP3E@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
CMS1_k127_5996628_1	1380763.BG53_13305	7.311e-89	297.0	COG0605@1|root,COG0605@2|Bacteria,1TPXT@1239|Firmicutes,4HA6U@91061|Bacilli,26QNA@186822|Paenibacillaceae	91061|Bacilli	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodA	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
CMS1_k127_5996628_2	756272.Plabr_3975	1.197e-16	83.0	COG2331@1|root,COG2331@2|Bacteria,2J0TW@203682|Planctomycetes	203682|Planctomycetes	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
CMS1_k127_5996628_0	1121405.dsmv_0937	2.353e-116	385.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,42MHH@68525|delta/epsilon subdivisions,2WIMW@28221|Deltaproteobacteria,2MHRT@213118|Desulfobacterales	28221|Deltaproteobacteria	E	TIGRFAM acetylornithine and succinylornithine	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iAF987.Gmet_0204	Aminotran_3
CMS1_k127_5999819_0	1056820.KB900629_gene1728	2.977e-248	768.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,1RMYX@1236|Gammaproteobacteria,2PMSJ@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	J	Elongation factor Tu GTP binding domain	tuf	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
CMS1_k127_5999819_1	1415778.JQMM01000001_gene394	4.028e-196	614.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,1RNSZ@1236|Gammaproteobacteria,1J4UF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
CMS1_k127_6005638_8	1128421.JAGA01000002_gene1353	8.984e-17	88.0	COG5305@1|root,COG5305@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2142,PMT_2
CMS1_k127_6005638_3	926550.CLDAP_34850	6.667e-108	359.0	COG0647@1|root,COG0647@2|Bacteria,2G60W@200795|Chloroflexi	200795|Chloroflexi	G	COGs COG0647 sugar phosphatase of the HAD superfamily	-	-	-	ko:K02566	-	-	-	-	ko00000	-	-	-	Hydrolase_6,Hydrolase_like
CMS1_k127_6005638_5	163908.KB235896_gene3592	3.174e-92	310.0	COG0412@1|root,COG0412@2|Bacteria,1G4HV@1117|Cyanobacteria,1HMQR@1161|Nostocales	1117|Cyanobacteria	Q	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DLH
CMS1_k127_6005638_2	616991.JPOO01000003_gene1759	1.973e-128	424.0	2CAEK@1|root,2ZCPG@2|Bacteria,4P1ZI@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_6005638_6	1292035.H476_1662	2.67e-36	156.0	COG0451@1|root,COG0451@2|Bacteria,1V04J@1239|Firmicutes,24CFZ@186801|Clostridia	186801|Clostridia	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_6005638_1	1123242.JH636434_gene4680	2.212e-151	484.0	COG0363@1|root,COG0363@2|Bacteria,2IXX0@203682|Planctomycetes	203682|Planctomycetes	G	Glucosamine-6-phosphate isomerase	-	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	-
CMS1_k127_6005638_4	886293.Sinac_5439	1.53e-92	314.0	COG1218@1|root,COG1218@2|Bacteria,2IYDK@203682|Planctomycetes	203682|Planctomycetes	P	COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase	-	-	3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Inositol_P
CMS1_k127_6005638_0	986075.CathTA2_2241	8.749e-242	762.0	COG1620@1|root,COG1620@2|Bacteria,1TQNM@1239|Firmicutes,4HAF3@91061|Bacilli	91061|Bacilli	C	L-lactate permease	-	-	-	ko:K03303	-	-	-	-	ko00000,ko02000	2.A.14	-	-	Lactate_perm
CMS1_k127_6005638_7	395019.Bmul_2246	1.232e-19	91.0	COG2267@1|root,COG2267@2|Bacteria,1MWF5@1224|Proteobacteria,2VNMX@28216|Betaproteobacteria,1K072@119060|Burkholderiaceae	28216|Betaproteobacteria	I	PFAM alpha beta hydrolase fold	pldB	-	3.1.1.5	ko:K01048	ko00564,map00564	-	-	-	ko00000,ko00001,ko01000	-	-	-	Hydrolase_4
CMS1_k127_6011615_1	857087.Metme_0096	1.249e-35	140.0	COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,1RMMT@1236|Gammaproteobacteria,1XECR@135618|Methylococcales	135618|Methylococcales	M	Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate	mpl	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS1_k127_6011615_2	1496688.ER33_15505	4.045e-34	143.0	COG0805@1|root,COG0805@2|Bacteria,1FZZ8@1117|Cyanobacteria,22S4S@167375|Cyanobium	1117|Cyanobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
CMS1_k127_6011615_0	243090.RB12202	4.755e-106	364.0	COG0582@1|root,COG0582@2|Bacteria,2J2X9@203682|Planctomycetes	203682|Planctomycetes	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
CMS1_k127_6011615_4	1123242.JH636435_gene1986	1.138e-12	70.0	2DFN0@1|root,2ZSD2@2|Bacteria,2J4C8@203682|Planctomycetes	203682|Planctomycetes	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
CMS1_k127_6017409_0	316057.RPD_0691	3.066e-53	192.0	COG1024@1|root,COG1024@2|Bacteria,1MXZ2@1224|Proteobacteria,2TRQ8@28211|Alphaproteobacteria,3JVYF@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	enoyl-CoA hydratase	MA20_25215	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS1_k127_6017409_1	1463864.JOGO01000063_gene5043	2.96e-42	176.0	COG0515@1|root,COG0515@2|Bacteria,2GNG1@201174|Actinobacteria	201174|Actinobacteria	KLT	Serine threonine protein kinase	pksC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
CMS1_k127_6017409_2	883081.HMPREF9698_01275	8.315e-05	55.0	COG1388@1|root,COG1388@2|Bacteria,1UHY7@1239|Firmicutes,4ISAN@91061|Bacilli,27GR1@186828|Carnobacteriaceae	91061|Bacilli	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
CMS1_k127_6028078_0	635013.TherJR_1892	1.152e-72	271.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS1_k127_6028078_3	886293.Sinac_4642	5.336e-25	109.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
CMS1_k127_6028078_2	330214.NIDE0017	2.903e-33	129.0	COG3369@1|root,COG3369@2|Bacteria,3J1A6@40117|Nitrospirae	40117|Nitrospirae	S	Iron-binding zinc finger CDGSH type	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
CMS1_k127_6028078_1	1384066.JAGT01000001_gene2667	1.4e-43	170.0	COG1215@1|root,COG1215@2|Bacteria,1V0FP@1239|Firmicutes	1239|Firmicutes	M	glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_7C,Glycos_transf_2
CMS1_k127_6041907_0	886293.Sinac_0388	1.61e-142	461.0	COG1621@1|root,COG1621@2|Bacteria,2IZ2Q@203682|Planctomycetes	203682|Planctomycetes	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_6041907_1	760192.Halhy_3573	6.461e-16	83.0	COG4225@1|root,COG4225@2|Bacteria,4NF1N@976|Bacteroidetes,1IP96@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Heparinase II III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4962,Hepar_II_III
CMS1_k127_6047655_1	991905.SL003B_3000	2.671e-08	64.0	COG5126@1|root,COG5126@2|Bacteria,1NH5D@1224|Proteobacteria,2UF3D@28211|Alphaproteobacteria,4BT5E@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	DTZ	EF-hand, calcium binding motif	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_1,EF-hand_5
CMS1_k127_6047655_0	382464.ABSI01000007_gene4118	6.976e-95	317.0	COG0745@1|root,COG0745@2|Bacteria,46TFB@74201|Verrucomicrobia,2IUEX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_6047655_2	402777.KB235903_gene1701	2.6e-06	52.0	COG0642@1|root,COG2205@2|Bacteria,1G06M@1117|Cyanobacteria,1H95E@1150|Oscillatoriales	1117|Cyanobacteria	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
CMS1_k127_6047888_1	1123242.JH636434_gene5339	1.888e-113	379.0	COG0673@1|root,COG0673@2|Bacteria,2IXA3@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_6047888_3	761193.Runsl_2218	1.592e-36	158.0	COG1413@1|root,COG1413@2|Bacteria,4NEZ7@976|Bacteroidetes,47MYP@768503|Cytophagia	976|Bacteroidetes	C	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080,HEAT_2
CMS1_k127_6047888_2	234267.Acid_0038	9.817e-104	367.0	COG5434@1|root,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_49N,Hepar_II_III,Hepar_II_III_N
CMS1_k127_6047888_0	111780.Sta7437_2178	1.981e-152	489.0	COG2230@1|root,COG2230@2|Bacteria,1G3TN@1117|Cyanobacteria	1117|Cyanobacteria	M	PFAM methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
CMS1_k127_6049357_1	548477.HMPREF0294_0332	1.597e-09	67.0	COG2885@1|root,COG3266@1|root,COG2885@2|Bacteria,COG3266@2|Bacteria,2I6XH@201174|Actinobacteria,22MTB@1653|Corynebacteriaceae	2|Bacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	Collagen,G5,TSP_3,YSIRK_signal
CMS1_k127_6049357_0	1047013.AQSP01000125_gene2621	1.259e-133	444.0	COG0591@1|root,COG0591@2|Bacteria	2|Bacteria	E	symporter activity	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
CMS1_k127_6053284_5	123214.PERMA_0875	3.505e-09	64.0	COG0564@1|root,COG0564@2|Bacteria,2G3QN@200783|Aquificae	200783|Aquificae	J	Responsible for synthesis of pseudouridine from uracil	-	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
CMS1_k127_6053284_0	1303518.CCALI_02069	1.126e-190	609.0	COG1070@1|root,COG1070@2|Bacteria	2|Bacteria	G	xylulokinase activity	xylB	-	2.7.1.12,2.7.1.17,2.7.1.5	ko:K00848,ko:K00851,ko:K00854	ko00030,ko00040,ko00051,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00040,map00051,map01100,map01110,map01120,map01130,map01200	M00014	R01639,R01737,R01902,R03014	RC00002,RC00017,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU17610	FGGY_C,FGGY_N
CMS1_k127_6053284_4	379066.GAU_1894	2.875e-09	59.0	COG0828@1|root,COG0828@2|Bacteria,1ZU81@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Ribosomal protein S21	-	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
CMS1_k127_6053284_3	373903.Hore_09350	5.578e-44	167.0	COG2065@1|root,COG2065@2|Bacteria,1V3GV@1239|Firmicutes,24FQD@186801|Clostridia,3WAIW@53433|Halanaerobiales	186801|Clostridia	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	iHN637.CLJU_RS05275	Pribosyltran
CMS1_k127_6053284_1	1089553.Tph_c14480	2.321e-106	358.0	COG0540@1|root,COG0540@2|Bacteria,1TQ96@1239|Firmicutes,2496D@186801|Clostridia,42EY2@68295|Thermoanaerobacterales	186801|Clostridia	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
CMS1_k127_6053284_2	443143.GM18_1721	5.946e-56	201.0	COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,42MJ9@68525|delta/epsilon subdivisions,2WJH8@28221|Deltaproteobacteria,43TM6@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
CMS1_k127_6068390_1	886293.Sinac_6034	9.776e-13	70.0	COG3502@1|root,COG3502@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF952)	-	-	2.3.2.29,2.5.1.18,3.8.1.2	ko:K00799,ko:K01560,ko:K09705,ko:K21420	ko00361,ko00480,ko00625,ko00980,ko00982,ko00983,ko01100,ko01120,ko01524,ko05200,ko05204,ko05225,ko05418,map00361,map00480,map00625,map00980,map00982,map00983,map01100,map01120,map01524,map05200,map05204,map05225,map05418	-	R03522,R05287,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11547,R11548,R11905	RC00004,RC00064,RC00069,RC00697,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	DUF952,GST_C_2,GST_N_3
CMS1_k127_6068390_0	1167006.UWK_00555	1.999e-36	151.0	COG3043@1|root,COG3043@2|Bacteria,1P0M5@1224|Proteobacteria,431MK@68525|delta/epsilon subdivisions,2WWRX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	anaerobic respiration	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_6070010_1	1274524.BSONL12_04374	2.377e-24	108.0	2E2AR@1|root,32XG5@2|Bacteria,1VHHN@1239|Firmicutes	1239|Firmicutes	S	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	AP2,HNH_3
CMS1_k127_6070010_0	285535.JOEY01000064_gene7614	1.053e-37	155.0	COG3547@1|root,COG3547@2|Bacteria,2IBF5@201174|Actinobacteria	201174|Actinobacteria	L	Transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
CMS1_k127_6076047_0	1210884.HG799464_gene10603	2.362e-11	78.0	2A5PP@1|root,30UEI@2|Bacteria,2J4IH@203682|Planctomycetes	1210884.HG799464_gene10603|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_6076984_2	646529.Desaci_0582	5.369e-33	139.0	COG0583@1|root,COG0583@2|Bacteria,1TQ6Y@1239|Firmicutes,25C6V@186801|Clostridia,262EZ@186807|Peptococcaceae	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS1_k127_6076984_0	635013.TherJR_0828	3.802e-121	399.0	COG0150@1|root,COG0150@2|Bacteria,1TP9J@1239|Firmicutes,248BT@186801|Clostridia,25ZYS@186807|Peptococcaceae	186801|Clostridia	F	PFAM AIR synthase related protein	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
CMS1_k127_6076984_1	243231.GSU1634	1.772e-110	373.0	COG0046@1|root,COG1828@1|root,COG0046@2|Bacteria,COG1828@2|Bacteria,1MYN4@1224|Proteobacteria,42M08@68525|delta/epsilon subdivisions,2WITS@28221|Deltaproteobacteria,43TKA@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,PurS
CMS1_k127_6087364_1	234267.Acid_4539	2.458e-117	387.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,3Y6VT@57723|Acidobacteria	57723|Acidobacteria	C	Malic enzyme, NAD binding domain	-	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,PTA_PTB,malic
CMS1_k127_6087364_0	1002809.SSIL_2408	9.14e-204	649.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4H9VR@91061|Bacilli,26DUZ@186818|Planococcaceae	91061|Bacilli	E	COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS1_k127_6087364_2	556261.HMPREF0240_03594	1.65e-54	198.0	COG0407@1|root,COG0407@2|Bacteria,1UZD2@1239|Firmicutes,24C43@186801|Clostridia,36H7R@31979|Clostridiaceae	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
CMS1_k127_6102338_8	237368.SCABRO_01254	1.035e-74	264.0	COG1570@1|root,COG1570@2|Bacteria,2IXGG@203682|Planctomycetes	203682|Planctomycetes	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
CMS1_k127_6102338_17	204669.Acid345_1573	3.839e-25	117.0	COG0457@1|root,COG0457@2|Bacteria	204669.Acid345_1573|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_6102338_11	1047013.AQSP01000066_gene721	1.234e-47	185.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	pilI	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
CMS1_k127_6102338_7	330214.NIDE3435	2.04e-76	268.0	COG1131@1|root,COG1131@2|Bacteria,3J122@40117|Nitrospirae	40117|Nitrospirae	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_6102338_12	349521.HCH_00733	1.55e-43	173.0	29681@1|root,2ZTI1@2|Bacteria,1RA8W@1224|Proteobacteria,1SAMV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Peptidase M50B-like	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50B
CMS1_k127_6102338_1	234267.Acid_2416	1.434e-172	556.0	COG4287@1|root,COG4287@2|Bacteria	2|Bacteria	S	PhoPQ-activated pathogenicity-related protein	pqaA	-	-	-	-	-	-	-	-	-	-	-	PhoPQ_related
CMS1_k127_6102338_15	243233.MCA2520	5.449e-34	135.0	COG1393@1|root,COG1393@2|Bacteria,1MZ4Z@1224|Proteobacteria,1S8XH@1236|Gammaproteobacteria,1XFED@135618|Methylococcales	135618|Methylococcales	C	arsenate reductase	-	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC
CMS1_k127_6102338_0	1322246.BN4_12700	3.706e-216	683.0	COG0388@1|root,COG0454@1|root,COG0388@2|Bacteria,COG0456@2|Bacteria,1MX4I@1224|Proteobacteria,42N4T@68525|delta/epsilon subdivisions,2WJK8@28221|Deltaproteobacteria,2MG4R@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,CN_hydrolase
CMS1_k127_6102338_22	1382304.JNIL01000001_gene779	1.582e-09	59.0	COG0454@1|root,COG0456@2|Bacteria,1U521@1239|Firmicutes,4HBEJ@91061|Bacilli	91061|Bacilli	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	ykwB	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS1_k127_6102338_3	1200792.AKYF01000027_gene598	6.738e-133	436.0	COG0277@1|root,COG0277@2|Bacteria,1TS7V@1239|Firmicutes,4HC0H@91061|Bacilli,26VYC@186822|Paenibacillaceae	91061|Bacilli	C	D-arabinono-1,4-lactone oxidase	-	-	1.1.3.41,1.1.3.8	ko:K00103,ko:K00594	ko00040,ko00051,ko00053,ko01100,map00040,map00051,map00053,map01100	M00129	R00647,R03184,R07152,R10053,R11620	RC00108,RC00133,RC00195,RC00346,RC00869	ko00000,ko00001,ko00002,ko01000	-	-	-	ALO,FAD_binding_4
CMS1_k127_6102338_6	477974.Daud_0339	8.042e-98	330.0	COG0002@1|root,COG0002@2|Bacteria,1TPVI@1239|Firmicutes,247R3@186801|Clostridia,2602H@186807|Peptococcaceae	186801|Clostridia	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
CMS1_k127_6102338_4	1410665.JNKR01000007_gene653	3.939e-113	377.0	COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,4H2TK@909932|Negativicutes	909932|Negativicutes	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
CMS1_k127_6102338_5	340099.Teth39_0225	1.088e-101	339.0	COG0548@1|root,COG0548@2|Bacteria,1TP0N@1239|Firmicutes,2486J@186801|Clostridia,42ET5@68295|Thermoanaerobacterales	186801|Clostridia	F	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10565	AA_kinase
CMS1_k127_6102338_10	1499967.BAYZ01000065_gene6092	8.625e-50	184.0	COG0811@1|root,COG0811@2|Bacteria,2NPUZ@2323|unclassified Bacteria	2|Bacteria	U	MotA/TolQ/ExbB proton channel family	exbB2	-	-	ko:K03561,ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	MotA_ExbB
CMS1_k127_6102338_20	261292.Nit79A3_1093	4.141e-15	81.0	COG0848@1|root,COG0848@2|Bacteria,1PWMP@1224|Proteobacteria,2W0NC@28216|Betaproteobacteria,3747F@32003|Nitrosomonadales	28216|Betaproteobacteria	U	PFAM Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
CMS1_k127_6102338_24	1444711.CCJF01000004_gene1832	4.851e-05	50.0	2E91F@1|root,333AR@2|Bacteria,2JGFK@204428|Chlamydiae	204428|Chlamydiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_6102338_16	292459.STH2428	8.912e-33	135.0	COG0491@1|root,COG0491@2|Bacteria,1V6FA@1239|Firmicutes,24JGV@186801|Clostridia	186801|Clostridia	P	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS1_k127_6102338_18	1254432.SCE1572_12065	1.082e-20	98.0	COG1357@1|root,COG1357@2|Bacteria,1N7U9@1224|Proteobacteria,42UJ1@68525|delta/epsilon subdivisions,2WR2I@28221|Deltaproteobacteria,2YZRT@29|Myxococcales	28221|Deltaproteobacteria	S	low-complexity proteins	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
CMS1_k127_6102338_21	886293.Sinac_1628	1.936e-11	72.0	COG0515@1|root,COG0515@2|Bacteria,2IZ17@203682|Planctomycetes	203682|Planctomycetes	KLT	Tyrosine protein kinase Serine threonine protein kinase PASTA	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS1_k127_6102338_2	323848.Nmul_A2377	1.704e-157	507.0	COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,2VID7@28216|Betaproteobacteria,371RE@32003|Nitrosomonadales	28216|Betaproteobacteria	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
CMS1_k127_6102338_13	237368.SCABRO_00501	2.556e-41	154.0	COG2154@1|root,COG2154@2|Bacteria,2J0CT@203682|Planctomycetes	203682|Planctomycetes	H	PFAM Pterin 4 alpha carbinolamine dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
CMS1_k127_6102338_9	1131269.AQVV01000028_gene40	3.219e-56	206.0	COG0694@1|root,COG0694@2|Bacteria	2|Bacteria	O	iron-sulfur cluster assembly	nfuA	-	-	ko:K07400	-	-	-	-	ko00000	-	-	-	Nfu_N,NifU
CMS1_k127_6107045_2	288000.BBta_1713	3.945e-05	54.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2TRFB@28211|Alphaproteobacteria,3JRIY@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Belongs to the peptidase M16 family	MA20_05655	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
CMS1_k127_6107045_1	762211.BSTEL_0365	1.39e-12	76.0	COG1725@1|root,COG1725@2|Bacteria,2IMER@201174|Actinobacteria,4D16Q@85004|Bifidobacteriales	201174|Actinobacteria	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
CMS1_k127_6107045_0	240016.ABIZ01000001_gene4894	1.383e-129	433.0	COG3420@1|root,COG3420@2|Bacteria,46US8@74201|Verrucomicrobia,2IV9B@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
CMS1_k127_6110446_2	555079.Toce_1641	1.114e-49	181.0	COG0778@1|root,COG0778@2|Bacteria,1UB8S@1239|Firmicutes,249SD@186801|Clostridia,42GNM@68295|Thermoanaerobacterales	186801|Clostridia	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase,TM1586_NiRdase
CMS1_k127_6110446_3	880072.Desac_2120	8.375e-16	83.0	2ES6V@1|root,33JRM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_6110446_1	96561.Dole_0148	2.672e-50	197.0	COG1305@1|root,COG1305@2|Bacteria,1RARF@1224|Proteobacteria,42R14@68525|delta/epsilon subdivisions,2WN3R@28221|Deltaproteobacteria,2MJNR@213118|Desulfobacterales	28221|Deltaproteobacteria	E	PFAM transglutaminase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
CMS1_k127_6110446_0	1209989.TepiRe1_0888	3.602e-278	880.0	COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,247N2@186801|Clostridia,42ETW@68295|Thermoanaerobacterales	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
CMS1_k127_6112308_4	1123252.ATZF01000001_gene1545	8.388e-08	60.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,4HDN8@91061|Bacilli,27C0D@186824|Thermoactinomycetaceae	91061|Bacilli	M	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
CMS1_k127_6112308_3	177439.DP2825	6.118e-10	65.0	COG5652@1|root,COG5652@2|Bacteria,1NB26@1224|Proteobacteria,42VNM@68525|delta/epsilon subdivisions,2WS4R@28221|Deltaproteobacteria,2MM1X@213118|Desulfobacterales	28221|Deltaproteobacteria	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
CMS1_k127_6112308_0	991905.SL003B_2051	7.119e-111	386.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,2USBB@28211|Alphaproteobacteria,4BP6U@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	M	PFAM Penicillin binding protein transpeptidase domain	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	PCB_OB,Transgly,Transpeptidase
CMS1_k127_6112308_2	1118054.CAGW01000020_gene4224	1.264e-49	183.0	COG0817@1|root,COG0817@2|Bacteria,1V3N9@1239|Firmicutes,4HGM3@91061|Bacilli,26SYI@186822|Paenibacillaceae	91061|Bacilli	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
CMS1_k127_6112308_1	706587.Desti_1416	5.161e-91	306.0	COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,42N7Q@68525|delta/epsilon subdivisions,2WJ1I@28221|Deltaproteobacteria,2MQ9Z@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	transcriptional regulatory protein	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
CMS1_k127_6122918_1	344747.PM8797T_09479	1.856e-76	272.0	COG2382@1|root,COG2382@2|Bacteria,2J2KX@203682|Planctomycetes	203682|Planctomycetes	P	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
CMS1_k127_6122918_0	247490.KSU1_C1312	6.805e-113	381.0	COG0128@1|root,COG0128@2|Bacteria,2IXRF@203682|Planctomycetes	203682|Planctomycetes	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
CMS1_k127_6122918_2	518766.Rmar_1448	6.099e-69	244.0	COG1912@1|root,COG1912@2|Bacteria,4NG9Y@976|Bacteroidetes,1FIS0@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
CMS1_k127_6122918_3	391625.PPSIR1_09091	9.921e-40	159.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,43BQ2@68525|delta/epsilon subdivisions,2WQ6X@28221|Deltaproteobacteria,2Z2WS@29|Myxococcales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GGDEF,Yop-YscD_cpl
CMS1_k127_6122918_4	1459636.NTE_03320	1.088e-13	74.0	COG2146@1|root,arCOG02852@2157|Archaea	2157|Archaea	P	COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases	-	-	1.7.1.15	ko:K00363,ko:K15762	ko00623,ko00910,ko00920,ko01100,ko01120,ko01220,map00623,map00910,map00920,map01100,map01120,map01220	M00530,M00538	R00787,R02550,R03562,R05666,R09513	RC00176,RC00269,RC00490,RC02556	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,Rieske_2
CMS1_k127_6135819_1	102129.Lepto7375DRAFT_5059	4.687e-205	647.0	COG0028@1|root,COG2146@1|root,COG0028@2|Bacteria,COG2146@2|Bacteria,1G4R6@1117|Cyanobacteria,1HAC6@1150|Oscillatoriales	1117|Cyanobacteria	H	Thiamine pyrophosphate enzyme, central domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS1_k127_6135819_0	111781.Lepto7376_2297	4.478e-259	809.0	COG0069@1|root,COG2146@1|root,COG0069@2|Bacteria,COG2146@2|Bacteria,1G0XM@1117|Cyanobacteria,1H8GB@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Conserved region in glutamate synthase	-	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase
CMS1_k127_6135819_2	1185876.BN8_02789	4.216e-33	138.0	29EN4@1|root,301K2@2|Bacteria,4NRU9@976|Bacteroidetes,47TPC@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_6136437_5	1347393.HG726028_gene2137	1.684e-08	66.0	2CB8C@1|root,33T5I@2|Bacteria,4P0N1@976|Bacteroidetes,2FX4B@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_6136437_4	1313172.YM304_11520	1.251e-17	93.0	COG2047@1|root,COG2047@2|Bacteria,2I2H9@201174|Actinobacteria,4CN4A@84992|Acidimicrobiia	84992|Acidimicrobiia	S	PAC2 family	-	-	-	-	-	-	-	-	-	-	-	-	PAC2
CMS1_k127_6136437_1	880073.Calab_0984	5.58e-103	351.0	COG0265@1|root,COG0265@2|Bacteria,2NQK9@2323|unclassified Bacteria	2|Bacteria	O	Trypsin	degQ	-	3.4.21.107	ko:K04771,ko:K04772	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
CMS1_k127_6136437_3	880073.Calab_0985	2.741e-39	164.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	FGE-sulfatase,PDZ_2
CMS1_k127_6136437_6	876044.IMCC3088_1586	0.0003947	51.0	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,1RQWA@1236|Gammaproteobacteria,1J6G5@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	D	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	cpoB	GO:0005575,GO:0005623,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043933,GO:0044085,GO:0044464,GO:0051259,GO:0051260,GO:0051301,GO:0065003,GO:0071840	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TolA_bind_tri
CMS1_k127_6136437_2	1121019.AUMN01000032_gene3083	1.106e-91	318.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria	201174|Actinobacteria	P	Pfam Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase,Sulfatase_C
CMS1_k127_6136437_0	1121406.JAEX01000019_gene2772	1.732e-104	356.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,42M6V@68525|delta/epsilon subdivisions,2WJCI@28221|Deltaproteobacteria,2M865@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
CMS1_k127_6141361_0	443143.GM18_3783	7.583e-18	96.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,42RVN@68525|delta/epsilon subdivisions,2WNJW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
CMS1_k127_6142472_0	572477.Alvin_1695	3.415e-150	487.0	COG0582@1|root,COG0582@2|Bacteria,1N2H9@1224|Proteobacteria,1RY6S@1236|Gammaproteobacteria,1WXWP@135613|Chromatiales	135613|Chromatiales	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_3,Phage_integrase
CMS1_k127_6148917_3	395963.Bind_2736	1.319e-14	87.0	COG0457@1|root,COG0457@2|Bacteria,1QY6N@1224|Proteobacteria,2U9DT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	ST7
CMS1_k127_6148917_1	56110.Oscil6304_5139	3.085e-47	191.0	COG4974@1|root,COG4974@2|Bacteria,1G7AU@1117|Cyanobacteria,1HHKG@1150|Oscillatoriales	1117|Cyanobacteria	L	PFAM Plasmid pRiA4b ORF-3-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3
CMS1_k127_6148917_0	452637.Oter_2054	8.416e-215	680.0	COG0459@1|root,COG0459@2|Bacteria,46S9U@74201|Verrucomicrobia,3K7T7@414999|Opitutae	414999|Opitutae	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	-	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
CMS1_k127_6148917_2	497964.CfE428DRAFT_3173	2.794e-46	173.0	COG0673@1|root,COG0673@2|Bacteria,46TMF@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_6163479_0	1121904.ARBP01000004_gene787	3.641e-196	625.0	COG5492@1|root,COG5492@2|Bacteria,4NEAB@976|Bacteroidetes,47TBW@768503|Cytophagia	976|Bacteroidetes	N	Domain of unknown function (DUF5060)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2,DUF5060
CMS1_k127_6172430_8	177437.HRM2_08660	9.002e-61	219.0	COG1063@1|root,COG1063@2|Bacteria,1QA80@1224|Proteobacteria	1224|Proteobacteria	E	L-sorbose 1-phosphate reductase	-	-	-	ko:K19956	ko00051,map00051	-	R03234	RC00089	ko00000,ko00001,ko01000	-	-	-	ADH_N
CMS1_k127_6172430_7	1499967.BAYZ01000095_gene4059	5.612e-65	232.0	COG3347@1|root,COG3347@2|Bacteria	2|Bacteria	IQ	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
CMS1_k127_6172430_13	1382359.JIAL01000001_gene1743	3.411e-28	127.0	COG2971@1|root,COG2971@2|Bacteria,3Y2J3@57723|Acidobacteria,2JIGZ@204432|Acidobacteriia	204432|Acidobacteriia	G	BadF/BadG/BcrA/BcrD ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
CMS1_k127_6172430_12	1122927.KB895414_gene5235	1.422e-38	157.0	COG4821@1|root,COG4821@2|Bacteria,1TQS7@1239|Firmicutes,4HCR4@91061|Bacilli,26R77@186822|Paenibacillaceae	91061|Bacilli	S	SIS domain	-	-	-	-	-	-	-	-	-	-	-	-	SIS_2
CMS1_k127_6172430_0	697281.Mahau_2023	4.358e-211	683.0	COG0383@1|root,COG0383@2|Bacteria,1TQEH@1239|Firmicutes,24DH1@186801|Clostridia	186801|Clostridia	G	Alpha mannosidase, middle domain	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
CMS1_k127_6172430_3	886293.Sinac_1691	1.566e-112	389.0	COG3379@1|root,COG3379@2|Bacteria,2IXA8@203682|Planctomycetes	203682|Planctomycetes	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
CMS1_k127_6172430_9	1423321.AS29_04220	1.075e-57	214.0	COG1073@1|root,COG1073@2|Bacteria,1UKWE@1239|Firmicutes,4ITSD@91061|Bacilli	91061|Bacilli	S	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
CMS1_k127_6172430_4	1128421.JAGA01000002_gene222	4.506e-104	347.0	COG0714@1|root,COG0714@2|Bacteria,2NNMQ@2323|unclassified Bacteria	2|Bacteria	S	ATPase associated with various cellular	moxR1	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS1_k127_6172430_14	391625.PPSIR1_22986	5.105e-24	116.0	COG1721@1|root,COG1721@2|Bacteria,1N8IQ@1224|Proteobacteria,42S2K@68525|delta/epsilon subdivisions,2WNA2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CMS1_k127_6172430_11	502025.Hoch_6586	3.21e-44	184.0	COG1305@1|root,COG1305@2|Bacteria,1MWCE@1224|Proteobacteria,42NIZ@68525|delta/epsilon subdivisions,2WM5U@28221|Deltaproteobacteria,2Z315@29|Myxococcales	28221|Deltaproteobacteria	E	Domain of unknown function (DUF3488)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3488,DUF4129,Transglut_core
CMS1_k127_6172430_10	1123269.NX02_27630	6.852e-48	187.0	COG2706@1|root,COG2706@2|Bacteria,1RB92@1224|Proteobacteria,2UJDW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
CMS1_k127_6172430_6	266117.Rxyl_2988	2.687e-87	300.0	COG1995@1|root,COG1995@2|Bacteria,2GRPG@201174|Actinobacteria	201174|Actinobacteria	H	Belongs to the PdxA family	pdxA	-	1.1.1.262,1.1.1.408,1.1.1.409	ko:K00097,ko:K22024	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
CMS1_k127_6172430_1	1123226.KB899284_gene3654	6.169e-139	456.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,4H9MW@91061|Bacilli,26QJZ@186822|Paenibacillaceae	91061|Bacilli	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
CMS1_k127_6172430_2	269799.Gmet_0138	5.983e-133	444.0	COG5316@1|root,COG5316@2|Bacteria,1QCVP@1224|Proteobacteria,42QA4@68525|delta/epsilon subdivisions,2WKD1@28221|Deltaproteobacteria,43SDE@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139,DUF4140
CMS1_k127_6172430_5	269799.Gmet_0138	4.363e-90	308.0	COG5316@1|root,COG5316@2|Bacteria,1QCVP@1224|Proteobacteria,42QA4@68525|delta/epsilon subdivisions,2WKD1@28221|Deltaproteobacteria,43SDE@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139,DUF4140
CMS1_k127_6186069_5	1123226.KB899313_gene1826	6.176e-07	57.0	294EW@1|root,2ZRUR@2|Bacteria,1V3SI@1239|Firmicutes,4HHJB@91061|Bacilli,26S1P@186822|Paenibacillaceae	91061|Bacilli	S	Protein of unknown function (DUF1569)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1569
CMS1_k127_6186069_0	1232410.KI421413_gene595	1.088e-140	458.0	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,42KZG@68525|delta/epsilon subdivisions,2WIQ5@28221|Deltaproteobacteria,43SCX@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Carbamoyl-phosphate synthase small chain, CPSase domain	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
CMS1_k127_6186069_1	1396418.BATQ01000113_gene4620	4.774e-113	370.0	COG1082@1|root,COG1082@2|Bacteria,46TV1@74201|Verrucomicrobia,2IU73@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS1_k127_6186069_3	1173264.KI913949_gene1594	8.384e-28	115.0	COG1708@1|root,COG1708@2|Bacteria,1GFNT@1117|Cyanobacteria,1HGFQ@1150|Oscillatoriales	1117|Cyanobacteria	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
CMS1_k127_6186069_4	768671.ThimaDRAFT_4613	4.386e-11	70.0	COG2250@1|root,COG2250@2|Bacteria	2|Bacteria	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
CMS1_k127_6186069_2	1122605.KB893625_gene1928	2.197e-49	186.0	2AF40@1|root,3152Q@2|Bacteria,4P1UF@976|Bacteroidetes,1IX0U@117747|Sphingobacteriia	976|Bacteroidetes	S	Heparinase II/III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III
CMS1_k127_6221183_1	1449353.JQMQ01000005_gene1507	0.0006011	53.0	COG4932@1|root,COG4932@2|Bacteria,2I3FW@201174|Actinobacteria	201174|Actinobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,MFS_1
CMS1_k127_6221183_0	1380384.JADN01000004_gene1756	0.0002478	46.0	COG1257@1|root,COG1257@2|Bacteria,4NGNG@976|Bacteroidetes,1HY0M@117743|Flavobacteriia	976|Bacteroidetes	I	Belongs to the HMG-CoA reductase family	mvaA	-	1.1.1.88	ko:K00054	ko00900,ko01110,ko01130,map00900,map01110,map01130	-	R02081	RC00004,RC00644	ko00000,ko00001,ko01000	-	-	-	HMG-CoA_red
CMS1_k127_6257193_2	401053.AciPR4_3984	1.516e-23	101.0	COG1724@1|root,COG1724@2|Bacteria	2|Bacteria	N	mRNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
CMS1_k127_6257193_1	744872.Spica_0096	1.122e-27	113.0	COG1598@1|root,COG1598@2|Bacteria	2|Bacteria	N	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
CMS1_k127_6257193_0	335543.Sfum_0261	1.721e-103	346.0	COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,42NBY@68525|delta/epsilon subdivisions,2WJV2@28221|Deltaproteobacteria,2MRV4@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	DnaJ molecular chaperone homology domain	cbpA	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
CMS1_k127_6259683_3	404589.Anae109_3433	6.445e-109	367.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WJ28@28221|Deltaproteobacteria,2YWA0@29|Myxococcales	28221|Deltaproteobacteria	NU	Type II/IV secretion system protein	pilT-1	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
CMS1_k127_6259683_4	1123250.KB908386_gene430	3.721e-98	334.0	COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,4H29A@909932|Negativicutes	909932|Negativicutes	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
CMS1_k127_6259683_12	211114.JOEF01000016_gene3597	1.64e-05	55.0	COG1589@1|root,COG1589@2|Bacteria,2H4A4@201174|Actinobacteria,4E3DB@85010|Pseudonocardiales	201174|Actinobacteria	D	Cell division protein FtsQ	ftsQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
CMS1_k127_6259683_1	1121403.AUCV01000008_gene1508	1.199e-119	400.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,42MMP@68525|delta/epsilon subdivisions,2WK50@28221|Deltaproteobacteria,2MIR1@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS1_k127_6259683_2	886293.Sinac_5304	3.951e-119	398.0	COG0477@1|root,COG2814@2|Bacteria,2IY3A@203682|Planctomycetes	203682|Planctomycetes	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
CMS1_k127_6259683_11	1121946.AUAX01000030_gene1268	4.634e-14	87.0	COG3661@1|root,COG3661@2|Bacteria,2ID53@201174|Actinobacteria,4DBMV@85008|Micromonosporales	201174|Actinobacteria	G	Glycosyl hydrolase family 67 C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_67C
CMS1_k127_6259683_9	643473.KB235930_gene2386	8.588e-47	177.0	COG3153@1|root,COG3153@2|Bacteria,1G5GM@1117|Cyanobacteria,1HU4Y@1161|Nostocales	1117|Cyanobacteria	S	Acetyltransferase (GNAT) domain	-	-	-	ko:K03824	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_7,Acetyltransf_9
CMS1_k127_6259683_8	246197.MXAN_5983	2.033e-71	253.0	COG4122@1|root,COG4122@2|Bacteria,1RB34@1224|Proteobacteria,43BAG@68525|delta/epsilon subdivisions,2X6PP@28221|Deltaproteobacteria,2YUZG@29|Myxococcales	28221|Deltaproteobacteria	H	O-methyltransferase	-	-	2.1.1.104	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	M00039,M00350	R01942,R06578	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_3
CMS1_k127_6259683_6	1121904.ARBP01000016_gene5249	7.948e-89	306.0	COG0715@1|root,COG0715@2|Bacteria,4NH2X@976|Bacteroidetes,47JPM@768503|Cytophagia	976|Bacteroidetes	P	Protein of unknown function (DUF3500)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3500
CMS1_k127_6259683_10	1121904.ARBP01000006_gene4028	8.267e-42	173.0	295NE@1|root,2ZSZT@2|Bacteria,4NPQK@976|Bacteroidetes	976|Bacteroidetes	S	DoxX	-	-	1.8.5.2	ko:K16937	ko00920,ko01120,map00920,map01120	-	R07177	-	ko00000,ko00001,ko01000	3.D.4.9	-	-	DoxX
CMS1_k127_6259683_7	709986.Deima_0142	4.989e-86	302.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	3.4.21.111	ko:K14645,ko:K20754	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Inhibitor_I9,Peptidase_S8
CMS1_k127_6259683_5	1123242.JH636436_gene704	7.852e-94	317.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_6259683_0	1047013.AQSP01000092_gene315	0.0	1094.0	COG3250@1|root,COG3250@2|Bacteria,2NQEM@2323|unclassified Bacteria	2|Bacteria	G	Glycosyl hydrolases family 2, TIM barrel domain	lacZ	GO:0003674,GO:0003824,GO:0004553,GO:0004565,GO:0005575,GO:0005975,GO:0005984,GO:0005988,GO:0005990,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009341,GO:0009987,GO:0015925,GO:0016052,GO:0016787,GO:0016798,GO:0032991,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0046352,GO:0071704,GO:1901575,GO:1902494	3.2.1.23,3.2.1.31	ko:K01190,ko:K01195	ko00040,ko00052,ko00511,ko00531,ko00600,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00052,map00511,map00531,map00600,map00860,map00944,map00983,map01100,map01110,map04142	M00014,M00076,M00077,M00078,M00129	R01105,R01478,R01678,R03355,R04783,R04979,R06114,R07818,R08127,R08260,R10830	RC00049,RC00055,RC00171,RC00452,RC00529,RC00530,RC00714,RC01251	ko00000,ko00001,ko00002,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
CMS1_k127_6259726_0	404589.Anae109_4094	0.0	1162.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42M0A@68525|delta/epsilon subdivisions,2WIQY@28221|Deltaproteobacteria,2YTXB@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
CMS1_k127_6269449_0	452637.Oter_1827	5.835e-187	609.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
CMS1_k127_6269449_1	861299.J421_0340	1.014e-10	71.0	COG3595@1|root,COG3595@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097,PA14
CMS1_k127_6275375_0	867903.ThesuDRAFT_00180	3.669e-11	65.0	COG0613@1|root,COG0613@2|Bacteria,1TPI5@1239|Firmicutes,248H2@186801|Clostridia,3WDAF@538999|Clostridiales incertae sedis	186801|Clostridia	S	DNA polymerase alpha chain like domain	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
CMS1_k127_62758_1	926550.CLDAP_14260	2.065e-66	235.0	COG3173@1|root,COG3173@2|Bacteria,2G5RM@200795|Chloroflexi	200795|Chloroflexi	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS1_k127_62758_0	1304885.AUEY01000003_gene480	1.184e-165	531.0	COG1960@1|root,COG1960@2|Bacteria,1MU2V@1224|Proteobacteria,42NKV@68525|delta/epsilon subdivisions,2WKPA@28221|Deltaproteobacteria,2MIDW@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS1_k127_62758_2	1123242.JH636434_gene4804	8.649e-53	195.0	COG0406@1|root,COG0406@2|Bacteria	2|Bacteria	G	alpha-ribazole phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
CMS1_k127_62758_3	1123256.KB907928_gene1969	8.849e-19	89.0	COG3411@1|root,COG3411@2|Bacteria,1MZR4@1224|Proteobacteria,1S8U3@1236|Gammaproteobacteria,1X7ZG@135614|Xanthomonadales	135614|Xanthomonadales	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	2Fe-2S_thioredx
CMS1_k127_6279092_7	983920.Y88_3528	6.324e-06	55.0	COG1596@1|root,COG1596@2|Bacteria,1RE48@1224|Proteobacteria,2U75D@28211|Alphaproteobacteria,2K5VV@204457|Sphingomonadales	204457|Sphingomonadales	M	Periplasmic protein involved in polysaccharide export	gumB	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
CMS1_k127_6279092_2	1379698.RBG1_1C00001G0159	4.746e-83	291.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS1_k127_6279092_0	1267535.KB906767_gene4059	4.563e-161	517.0	COG0677@1|root,COG0677@2|Bacteria,3Y30B@57723|Acidobacteria,2JIIN@204432|Acidobacteriia	204432|Acidobacteriia	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.136	ko:K13015	ko00520,map00520	-	R00421	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
CMS1_k127_6279092_6	596153.Alide_0763	4.585e-06	57.0	2B52F@1|root,31XVQ@2|Bacteria,1MYIZ@1224|Proteobacteria	1224|Proteobacteria	S	PEP-CTERM motif	-	-	-	-	-	-	-	-	-	-	-	-	DUF4114,VPEP
CMS1_k127_6279092_1	1379698.RBG1_1C00001G0159	1.278e-93	324.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS1_k127_6279092_5	871968.DESME_12390	4.796e-15	89.0	COG2204@1|root,COG2204@2|Bacteria,1VSKG@1239|Firmicutes,24ZP4@186801|Clostridia	186801|Clostridia	T	Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS1_k127_6279092_8	1304874.JAFY01000002_gene1064	4.961e-05	52.0	COG2199@1|root,COG3706@2|Bacteria,3TBG8@508458|Synergistetes	508458|Synergistetes	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
CMS1_k127_6279092_3	1121428.DESHY_60004___1	9.228e-83	288.0	COG1063@1|root,COG1063@2|Bacteria,1TPWP@1239|Firmicutes,24ATV@186801|Clostridia,263FM@186807|Peptococcaceae	186801|Clostridia	E	Zinc-binding dehydrogenase	ydjJ	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_6279092_4	1089547.KB913013_gene3053	8.238e-64	237.0	COG3356@1|root,COG3356@2|Bacteria,4NGDG@976|Bacteroidetes,47JVE@768503|Cytophagia	976|Bacteroidetes	S	Neutral/alkaline non-lysosomal ceramidase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
CMS1_k127_6279676_4	562970.Btus_3156	6.533e-160	516.0	COG0277@1|root,COG0277@2|Bacteria,1UIU4@1239|Firmicutes,4HBGZ@91061|Bacilli	91061|Bacilli	C	PFAM FAD linked oxidase domain protein	yitY	-	-	-	-	-	-	-	-	-	-	-	ALO,FAD_binding_4
CMS1_k127_6279676_0	649638.Trad_0897	0.0	1189.0	COG0567@1|root,COG0567@2|Bacteria,1WIKA@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	dehydrogenase e1 component	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
CMS1_k127_6279676_5	502025.Hoch_4995	1.154e-149	485.0	COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,42N18@68525|delta/epsilon subdivisions,2WJSK@28221|Deltaproteobacteria,2Z2W5@29|Myxococcales	28221|Deltaproteobacteria	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	sucB	-	2.3.1.12,2.3.1.61	ko:K00627,ko:K00658	ko00010,ko00020,ko00310,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00310,map00620,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032,M00307	R00209,R02569,R02570,R02571,R08549	RC00004,RC02727,RC02742,RC02833,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2766	2-oxoacid_dh,Biotin_lipoyl,E3_binding
CMS1_k127_6279676_9	215803.DB30_1378	7.878e-30	130.0	COG0597@1|root,COG0597@2|Bacteria,1N9NS@1224|Proteobacteria,432Z6@68525|delta/epsilon subdivisions,2WXKU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	MU	Signal peptidase (SPase) II	-	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
CMS1_k127_6279676_3	1123242.JH636434_gene4049	5.098e-203	640.0	COG1249@1|root,COG1249@2|Bacteria,2IX5H@203682|Planctomycetes	203682|Planctomycetes	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3)	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
CMS1_k127_6279676_8	1521187.JPIM01000076_gene1203	2.98e-41	155.0	COG2250@1|root,COG2250@2|Bacteria	2|Bacteria	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
CMS1_k127_6279676_6	330214.NIDE3942	1.807e-102	349.0	COG2204@1|root,COG2204@2|Bacteria,3J10B@40117|Nitrospirae	40117|Nitrospirae	T	Sigma-54 interaction domain	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS1_k127_6279676_10	1122603.ATVI01000012_gene1173	6.615e-11	77.0	COG0811@1|root,COG0811@2|Bacteria,1N2RJ@1224|Proteobacteria,1RMZK@1236|Gammaproteobacteria,1X3HR@135614|Xanthomonadales	135614|Xanthomonadales	U	Domain of unknown function (DUF2341)	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	DUF2341,Laminin_G_3,MotA_ExbB
CMS1_k127_6279676_7	1211813.CAPH01000013_gene540	6.636e-78	296.0	COG3533@1|root,COG3533@2|Bacteria,4NFW3@976|Bacteroidetes,2FRKH@200643|Bacteroidia	976|Bacteroidetes	S	Beta-L-arabinofuranosidase, GH127	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
CMS1_k127_6279676_2	1411123.JQNH01000001_gene1552	1.581e-205	653.0	COG0519@1|root,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,2TRN0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
CMS1_k127_6279676_1	1195236.CTER_3181	2.082e-245	766.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,247PS@186801|Clostridia,3WGWJ@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
CMS1_k127_641821_4	439235.Dalk_4663	3.073e-44	171.0	COG2866@1|root,COG2866@2|Bacteria,1MZYN@1224|Proteobacteria,42PTT@68525|delta/epsilon subdivisions,2WS13@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Zn_pept	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
CMS1_k127_641821_3	1173022.Cri9333_0167	2.277e-84	289.0	COG4106@1|root,COG4106@2|Bacteria,1G3BF@1117|Cyanobacteria,1H983@1150|Oscillatoriales	1117|Cyanobacteria	S	Methyltransferase type 11	-	-	2.1.1.144	ko:K00598	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
CMS1_k127_641821_1	1185876.BN8_01260	9.855e-125	426.0	COG2730@1|root,COG2730@2|Bacteria,4NGAC@976|Bacteroidetes,47MSS@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
CMS1_k127_641821_2	583355.Caka_0526	1.318e-113	376.0	COG1649@1|root,COG1649@2|Bacteria	2|Bacteria	F	PFAM Uncharacterised BCR, COG1649	-	-	3.2.1.11,3.2.1.18,3.2.1.35,4.2.2.23	ko:K01186,ko:K01197,ko:K05988,ko:K11931,ko:K18197	ko00500,ko00511,ko00531,ko00600,ko01100,ko02026,ko04142,map00500,map00511,map00531,map00600,map01100,map02026,map04142	M00076,M00077	R04018,R07824,R07825,R10905,R11309	RC00028,RC00077	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	-	GH33,GH66,PL11	-	DUF1349,GHL10,Glyco_hydro_20b,Laminin_G_3,NAGidase,fn3
CMS1_k127_641821_0	926569.ANT_14690	3.114e-127	412.0	28KX8@1|root,2ZAD8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_641821_6	1121904.ARBP01000028_gene1653	1.203e-16	82.0	COG3311@1|root,COG3311@2|Bacteria	2|Bacteria	K	DNA excision	-	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	HTH_17,PTS_EIIA_2
CMS1_k127_641821_5	1121904.ARBP01000028_gene1652	1.142e-24	107.0	COG2194@1|root,COG2194@2|Bacteria	2|Bacteria	T	sulfuric ester hydrolase activity	kbaA	GO:0008150,GO:0022603,GO:0042173,GO:0043937,GO:0043938,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0065007	2.7.8.43	ko:K03760,ko:K06349,ko:K19353	ko00540,ko01503,map00540,map01503	M00722	R11555,R11556,R11557	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DUF1705,KbaA,Sulfatase
CMS1_k127_652358_1	1303518.CCALI_00612	3.498e-28	125.0	COG0383@1|root,COG0383@2|Bacteria	2|Bacteria	G	mannose metabolic process	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
CMS1_k127_652358_0	1121918.ARWE01000001_gene746	3.001e-136	464.0	COG0457@1|root,COG0457@2|Bacteria,1R1JQ@1224|Proteobacteria,4377S@68525|delta/epsilon subdivisions,2WTFW@28221|Deltaproteobacteria,43U9G@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
CMS1_k127_652358_3	379066.GAU_3751	5.038e-05	53.0	COG0666@1|root,COG0666@2|Bacteria,1ZUHD@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Ankyrin repeats (many copies)	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2
CMS1_k127_652358_2	1267535.KB906767_gene2976	7.198e-19	88.0	COG3661@1|root,COG3661@2|Bacteria,3Y3Q5@57723|Acidobacteria,2JMHH@204432|Acidobacteriia	204432|Acidobacteriia	G	Belongs to the glycosyl hydrolase 67 family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_672551_1	472759.Nhal_1310	1.092e-90	304.0	COG1562@1|root,COG1562@2|Bacteria,1R4ZD@1224|Proteobacteria,1RS93@1236|Gammaproteobacteria,1X0KC@135613|Chromatiales	135613|Chromatiales	I	Squalene phytoene synthase	-	-	2.5.1.21	ko:K00801	ko00100,ko00909,ko01100,ko01110,ko01130,map00100,map00909,map01100,map01110,map01130	-	R00702,R02872,R06223	RC00362,RC00796,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	SQS_PSY
CMS1_k127_672551_0	1120950.KB892781_gene435	4.946e-96	328.0	COG5285@1|root,COG5285@2|Bacteria,2HZN9@201174|Actinobacteria,4DTAP@85009|Propionibacteriales	201174|Actinobacteria	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
CMS1_k127_672551_2	1499967.BAYZ01000170_gene5505	1.06e-38	155.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL,Lipase_GDSL_2
CMS1_k127_672551_3	927704.SELR_25840	2.918e-19	100.0	COG0795@1|root,COG0795@2|Bacteria,1TRZG@1239|Firmicutes,4H2PV@909932|Negativicutes	909932|Negativicutes	S	Permease, YjgP YjgQ family	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
CMS1_k127_672551_4	682795.AciX8_1309	8.431e-11	72.0	COG0795@1|root,COG0795@2|Bacteria,3Y2F9@57723|Acidobacteria,2JI5V@204432|Acidobacteriia	204432|Acidobacteriia	S	Permease, YjgP YjgQ	-	-	-	-	-	-	-	-	-	-	-	-	YjgP_YjgQ
CMS1_k127_678217_0	1492737.FEM08_17270	1.979e-124	423.0	COG0383@1|root,COG0383@2|Bacteria,4NGF5@976|Bacteroidetes,1I6I3@117743|Flavobacteriia	976|Bacteroidetes	G	Pfam Glycosyl hydrolases family 38 C-terminal domain	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Glyco_hydro_38,Glyco_hydro_38C
CMS1_k127_678217_2	391596.PBAL39_22770	1.148e-25	124.0	COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,1IQWC@117747|Sphingobacteriia	976|Bacteroidetes	G	Polysaccharide lyase family 4, domain III	-	-	-	-	-	-	-	-	-	-	-	-	CBM-like,Glyco_hydro_92
CMS1_k127_678217_1	1408473.JHXO01000001_gene2487	1.444e-58	211.0	COG0673@1|root,COG0673@2|Bacteria,4NEN5@976|Bacteroidetes,2FQ0Q@200643|Bacteroidia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_685241_0	941824.TCEL_01599	1.077e-125	410.0	COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,248F8@186801|Clostridia,36E6C@31979|Clostridiaceae	186801|Clostridia	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
CMS1_k127_685241_2	1232410.KI421413_gene667	3.844e-68	237.0	COG1238@1|root,COG1238@2|Bacteria,1MWED@1224|Proteobacteria,42TAU@68525|delta/epsilon subdivisions,2WPD6@28221|Deltaproteobacteria,43UN9@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
CMS1_k127_685241_1	243231.GSU1523	1.827e-77	272.0	COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,42N0I@68525|delta/epsilon subdivisions,2WMUX@28221|Deltaproteobacteria,43T33@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
CMS1_k127_685241_3	1280390.CBQR020000129_gene3230	4.571e-42	168.0	arCOG07336@1|root,2Z8ST@2|Bacteria,1TRXN@1239|Firmicutes,4HTI7@91061|Bacilli,271WP@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_696736_0	525904.Tter_2147	3.183e-95	330.0	COG2377@1|root,COG2377@2|Bacteria,2NNMN@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237	2.7.1.170,4.2.1.126	ko:K07106,ko:K09001	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	iECABU_c1320.ECABU_c18930,iECED1_1282.ECED1_1841,ic_1306.c2032	AnmK
CMS1_k127_696736_2	237368.SCABRO_03851	6.05e-17	90.0	COG2165@1|root,COG2165@2|Bacteria,2J0Q6@203682|Planctomycetes	203682|Planctomycetes	U	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CMS1_k127_696736_1	391625.PPSIR1_26408	1.29e-54	217.0	2CGJ6@1|root,31UKG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_696736_3	1120705.FG95_00901	0.0001239	54.0	COG4299@1|root,COG4299@2|Bacteria,1R5FB@1224|Proteobacteria,2U4I4@28211|Alphaproteobacteria,2K2AN@204457|Sphingomonadales	204457|Sphingomonadales	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
CMS1_k127_704462_9	1003200.AXXA_02078	4.155e-15	87.0	COG2207@1|root,COG2207@2|Bacteria,1R453@1224|Proteobacteria,2VNAV@28216|Betaproteobacteria,3T7GU@506|Alcaligenaceae	28216|Betaproteobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
CMS1_k127_704462_5	1469613.JT55_12095	2.292e-36	145.0	COG3647@1|root,COG3647@2|Bacteria,1RGJN@1224|Proteobacteria,2U80P@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_704462_1	234267.Acid_0588	4.81e-143	470.0	COG3829@1|root,COG3829@2|Bacteria	2|Bacteria	T	transcription factor binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
CMS1_k127_704462_6	697281.Mahau_1209	8.025e-34	143.0	COG0407@1|root,COG0407@2|Bacteria,1UY51@1239|Firmicutes,24DZF@186801|Clostridia,42FW9@68295|Thermoanaerobacterales	186801|Clostridia	H	PFAM Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
CMS1_k127_704462_3	1123277.KB893174_gene6062	1.108e-66	247.0	COG1520@1|root,COG1520@2|Bacteria,4NK4X@976|Bacteroidetes,47KWI@768503|Cytophagia	976|Bacteroidetes	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_704462_8	768704.Desmer_1347	2.138e-23	114.0	COG2247@1|root,COG3391@1|root,COG2247@2|Bacteria,COG3391@2|Bacteria,1V2E4@1239|Firmicutes,24TKC@186801|Clostridia	186801|Clostridia	M	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
CMS1_k127_704462_0	1211813.CAPH01000007_gene1792	0.0	1024.0	2DBGI@1|root,2Z94U@2|Bacteria,4NI4P@976|Bacteroidetes,2FWTC@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_704462_2	314230.DSM3645_27453	4.576e-126	417.0	COG0673@1|root,COG0673@2|Bacteria,2IXDR@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_704462_7	903818.KI912268_gene3129	1.873e-28	121.0	COG4254@1|root,COG4254@2|Bacteria	2|Bacteria	UW	PFAM FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
CMS1_k127_704462_4	56780.SYN_01064	8.097e-39	153.0	COG2885@1|root,COG2885@2|Bacteria,1MZKA@1224|Proteobacteria,42UAP@68525|delta/epsilon subdivisions,2WQWJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
CMS1_k127_727306_5	391165.GbCGDNIH1_0326	9.081e-40	152.0	COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,2TS6F@28211|Alphaproteobacteria,2JQ3D@204441|Rhodospirillales	204441|Rhodospirillales	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
CMS1_k127_727306_0	382464.ABSI01000010_gene3393	2.94e-151	491.0	COG0019@1|root,COG0019@2|Bacteria,46SC5@74201|Verrucomicrobia,2ITWM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Pyridoxal-dependent decarboxylase, pyridoxal binding domain	-	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
CMS1_k127_727306_1	1142394.PSMK_20110	1.6e-126	431.0	COG1266@1|root,COG1668@1|root,COG1266@2|Bacteria,COG1668@2|Bacteria,2IXUG@203682|Planctomycetes	203682|Planctomycetes	CP	COG1668 ABC-type Na efflux pump, permease component	-	-	-	ko:K01992,ko:K09696	ko02010,ko02020,map02010,map02020	M00253,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.115	-	-	ABC2_membrane_2,Abi
CMS1_k127_727306_3	926692.AZYG01000051_gene1850	1.107e-75	262.0	COG4555@1|root,COG4555@2|Bacteria,1UHYH@1239|Firmicutes,25E73@186801|Clostridia,3WBUT@53433|Halanaerobiales	186801|Clostridia	CP	ATPases associated with a variety of cellular activities	natA	-	3.6.3.7	ko:K09697	ko02010,ko02020,map02010,map02020	M00253	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.115	-	-	ABC_tran
CMS1_k127_727306_7	1499502.EV12_0944	7.177e-08	59.0	2DYAZ@1|root,348ZI@2|Bacteria,1GF7Z@1117|Cyanobacteria,1MNUQ@1212|Prochloraceae	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_727306_2	1047013.AQSP01000126_gene2736	3.83e-95	319.0	COG1028@1|root,COG1028@2|Bacteria,2NQUH@2323|unclassified Bacteria	2|Bacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS1_k127_727306_6	1536769.P40081_09615	1.303e-19	102.0	COG1520@1|root,COG1520@2|Bacteria,1UIHU@1239|Firmicutes,4ISIB@91061|Bacilli,2773B@186822|Paenibacillaceae	91061|Bacilli	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_727306_4	1396418.BATQ01000078_gene616	4.107e-41	170.0	COG1621@1|root,COG1621@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 32 family	-	-	3.1.3.6,3.1.4.16	ko:K01119	ko00230,ko00240,map00230,map00240	-	R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135	RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	SLH
CMS1_k127_73463_6	1550073.JROH01000009_gene1300	1.956e-07	54.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,2K2HE@204457|Sphingomonadales	204457|Sphingomonadales	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
CMS1_k127_73463_1	1122164.JHWF01000003_gene2125	1.569e-44	177.0	COG1357@1|root,COG1357@2|Bacteria,1PHB3@1224|Proteobacteria,1T7FB@1236|Gammaproteobacteria,1JFB2@118969|Legionellales	118969|Legionellales	P	Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
CMS1_k127_73463_0	911045.PSE_0625	2.126e-66	234.0	COG2356@1|root,COG2356@2|Bacteria,1MXQM@1224|Proteobacteria,2UEGK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Endonuclease I	-	-	3.1.21.1	ko:K01150	-	-	-	-	ko00000,ko01000	-	-	-	Endonuclease_1
CMS1_k127_73463_2	1229487.AMYW01000002_gene1666	1.736e-25	114.0	2EK7Y@1|root,30D58@2|Bacteria,4PFHZ@976|Bacteroidetes,1IAR3@117743|Flavobacteriia,2NXNE@237|Flavobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_736302_4	268407.PWYN_10910	7.566e-29	126.0	COG0778@1|root,COG0778@2|Bacteria,1UWU9@1239|Firmicutes,4H9ZQ@91061|Bacilli,26UIF@186822|Paenibacillaceae	91061|Bacilli	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CMS1_k127_736302_3	203275.BFO_0735	8.612e-38	158.0	COG1944@1|root,COG1944@2|Bacteria,4NTYG@976|Bacteroidetes,2FZAU@200643|Bacteroidia	976|Bacteroidetes	S	YcaO cyclodehydratase, ATP-ad Mg2+-binding	-	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	YcaO
CMS1_k127_736302_5	1440053.JOEI01000005_gene1785	4.48e-09	68.0	COG0476@1|root,COG0476@2|Bacteria,2HGW4@201174|Actinobacteria	201174|Actinobacteria	H	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
CMS1_k127_736302_1	1035308.AQYY01000002_gene1056	8.41e-106	355.0	2DB7V@1|root,2Z7NX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_736302_0	443143.GM18_1310	2.208e-155	508.0	COG0075@1|root,COG3916@1|root,COG0075@2|Bacteria,COG3916@2|Bacteria	2|Bacteria	QT	Acyl-homoserine-lactone synthase	-	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	AIRS,Acetyltransf_10,Acetyltransf_5,Aminotran_5
CMS1_k127_737250_2	1123070.KB899251_gene796	5.251e-130	440.0	COG0755@1|root,COG0755@2|Bacteria,46VBM@74201|Verrucomicrobia,2IU24@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Cytochrome C assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
CMS1_k127_737250_7	1403819.BATR01000162_gene5451	2.67e-65	239.0	COG1333@1|root,COG1333@2|Bacteria,46SUY@74201|Verrucomicrobia,2IUGM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	ResB-like family	-	-	-	-	-	-	-	-	-	-	-	-	ResB
CMS1_k127_737250_12	1121920.AUAU01000001_gene2237	1.265e-10	73.0	2E533@1|root,32ZW9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_737250_11	1403819.BATR01000162_gene5452	4.722e-38	158.0	2E533@1|root,32ZW9@2|Bacteria,46X7Y@74201|Verrucomicrobia,2IUXW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_737250_3	880073.Calab_3419	5.541e-129	425.0	COG1088@1|root,COG1088@2|Bacteria,2NNRC@2323|unclassified Bacteria	2|Bacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019305,GO:0019438,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044464,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0048037,GO:0050662,GO:0051287,GO:0055086,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576	4.2.1.46,4.2.1.76	ko:K01710,ko:K12450	ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130	M00793	R00293,R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3464	GDP_Man_Dehyd
CMS1_k127_737250_6	1380763.BG53_07580	9.293e-66	234.0	COG1091@1|root,COG1091@2|Bacteria,1TP71@1239|Firmicutes,4HBXF@91061|Bacilli,26SEN@186822|Paenibacillaceae	91061|Bacilli	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
CMS1_k127_737250_0	344747.PM8797T_25881	3.18e-156	512.0	COG3119@1|root,COG3119@2|Bacteria,2IX9T@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A and related enzymes	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	DUF4976,Sulfatase
CMS1_k127_737250_10	314230.DSM3645_20867	1.257e-50	190.0	COG0101@1|root,COG0101@2|Bacteria,2IYSC@203682|Planctomycetes	203682|Planctomycetes	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
CMS1_k127_737250_9	1267535.KB906767_gene5244	6.344e-62	230.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	DUF4976,Glyco_tranf_2_3,Glycos_transf_2,Sulfatase
CMS1_k127_737250_13	525904.Tter_2003	3.849e-08	64.0	COG1878@1|root,COG1878@2|Bacteria,2NRE5@2323|unclassified Bacteria	2|Bacteria	S	Putative cyclase	-	-	1.1.1.363,1.1.1.49,3.5.1.9	ko:K00036,ko:K07130	ko00030,ko00380,ko00480,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00380,map00480,map00630,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008,M00038	R00835,R00988,R01959,R02736,R04911,R10907	RC00001,RC00066,RC00263,RC00323	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cyclase
CMS1_k127_737250_5	331113.SNE_A14190	6.921e-72	250.0	COG0500@1|root,COG2226@2|Bacteria,2JG4F@204428|Chlamydiae	204428|Chlamydiae	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
CMS1_k127_737250_4	266117.Rxyl_2897	9.718e-117	391.0	COG1169@1|root,COG1169@2|Bacteria,2GKE8@201174|Actinobacteria,4CQEB@84995|Rubrobacteria	84995|Rubrobacteria	HQ	chorismate binding enzyme	menF	-	5.4.4.2	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
CMS1_k127_737250_1	266117.Rxyl_2896	9.677e-151	499.0	COG1165@1|root,COG1165@2|Bacteria,2GMEB@201174|Actinobacteria,4CPYA@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	-	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M_2,TPP_enzyme_N
CMS1_k127_737250_8	1173028.ANKO01000075_gene2992	3.948e-65	233.0	COG0596@1|root,COG0596@2|Bacteria,1GQ5T@1117|Cyanobacteria,1H97N@1150|Oscillatoriales	1117|Cyanobacteria	S	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)	menH	-	4.2.99.20	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08166	RC02148,RC02475	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1
CMS1_k127_740795_1	1210884.HG799465_gene12034	2.517e-08	66.0	COG5426@1|root,COG5426@2|Bacteria,2J52A@203682|Planctomycetes	203682|Planctomycetes	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_740795_0	314230.DSM3645_19006	2.898e-81	280.0	COG1131@1|root,COG1131@2|Bacteria,2IXFI@203682|Planctomycetes	203682|Planctomycetes	V	ABC-type multidrug transport system ATPase	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_745831_3	1142394.PSMK_04700	2.579e-49	184.0	COG0464@1|root,COG0464@2|Bacteria	2|Bacteria	O	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA,BCS1_N
CMS1_k127_745831_0	243231.GSU0623	1.441e-119	392.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,42MCE@68525|delta/epsilon subdivisions,2WIYP@28221|Deltaproteobacteria,43U7K@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Glycosyltransferase like family 2	-	-	2.4.2.53	ko:K10012	ko00520,ko01503,map00520,map01503	M00721,M00761	R07661	RC00005,RC02954	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	4.D.2.1.8	GT2	-	Glycos_transf_2
CMS1_k127_745831_4	314230.DSM3645_12181	2.239e-16	91.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CMS1_k127_745831_2	331113.SNE_A09210	6.281e-62	222.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,2JHEU@204428|Chlamydiae	204428|Chlamydiae	H	ThiF family	-	-	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
CMS1_k127_750434_4	78245.Xaut_0825	2.553e-34	139.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2TVTA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.109	ko:K19715	-	-	R11395	RC00160	ko00000,ko01000,ko01005	-	-	-	DegT_DnrJ_EryC1
CMS1_k127_750434_2	1410620.SHLA_34c000660	5.233e-85	299.0	COG0395@1|root,COG0395@2|Bacteria,1N0IZ@1224|Proteobacteria,2VEX4@28211|Alphaproteobacteria,4BNBZ@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_750434_3	1410620.SHLA_34c000670	1.526e-82	289.0	COG1175@1|root,COG1175@2|Bacteria,1MWB7@1224|Proteobacteria,2TQZY@28211|Alphaproteobacteria,4B6YP@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	permease	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_750434_1	43989.cce_1397	2.119e-142	469.0	COG1653@1|root,COG1653@2|Bacteria,1GM7A@1117|Cyanobacteria,3KJPC@43988|Cyanothece	1117|Cyanobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_1
CMS1_k127_750434_0	234267.Acid_7527	7.86e-150	501.0	COG3250@1|root,COG3250@2|Bacteria,3Y2PR@57723|Acidobacteria	57723|Acidobacteria	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.2.1.165	ko:K15855	ko00520,ko01100,map00520,map01100	-	R01966	RC00049	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2
CMS1_k127_750467_6	1123242.JH636435_gene1286	5.216e-16	78.0	COG1131@1|root,COG1131@2|Bacteria,2IY79@203682|Planctomycetes	203682|Planctomycetes	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_750467_3	1210884.HG799468_gene13554	1.022e-46	171.0	COG1725@1|root,COG1725@2|Bacteria,2J03Y@203682|Planctomycetes	203682|Planctomycetes	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
CMS1_k127_750467_4	1160707.AJIK01000011_gene2578	4.537e-35	148.0	COG0741@1|root,COG0741@2|Bacteria,1V6DD@1239|Firmicutes,4HIWA@91061|Bacilli,26FJU@186818|Planococcaceae	91061|Bacilli	M	Transglycosylase SLT domain	yjbJ	-	-	-	-	-	-	-	-	-	-	-	SLT
CMS1_k127_750467_2	234267.Acid_6216	1.454e-76	264.0	COG1212@1|root,COG1212@2|Bacteria,3Y4GZ@57723|Acidobacteria	57723|Acidobacteria	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
CMS1_k127_750467_0	1125863.JAFN01000001_gene910	7.111e-203	645.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,42MEU@68525|delta/epsilon subdivisions,2WJ0F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1276	CTP_synth_N,GATase
CMS1_k127_750467_1	1189612.A33Q_0282	1.534e-97	325.0	COG2120@1|root,COG2120@2|Bacteria,4NEDJ@976|Bacteroidetes,47TIE@768503|Cytophagia	976|Bacteroidetes	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
CMS1_k127_750467_5	63737.Npun_R3813	2.609e-32	136.0	COG0546@1|root,COG3502@1|root,COG0546@2|Bacteria,COG3502@2|Bacteria,1GQDN@1117|Cyanobacteria,1HNNX@1161|Nostocales	1117|Cyanobacteria	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_750467_8	344747.PM8797T_28764	6.769e-07	56.0	2DNKX@1|root,32Y1B@2|Bacteria,2J0P2@203682|Planctomycetes	203682|Planctomycetes	S	Glycine zipper	-	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_Omp
CMS1_k127_750467_7	595460.RRSWK_00419	6.66e-10	63.0	2DNKX@1|root,32Y1B@2|Bacteria,2J0P2@203682|Planctomycetes	203682|Planctomycetes	S	Glycine zipper	-	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_Omp
CMS1_k127_753432_1	926560.KE387027_gene366	7.64e-24	107.0	COG1680@1|root,COG1680@2|Bacteria,1WJK2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS1_k127_753432_0	1157490.EL26_09010	1.303e-65	231.0	COG1853@1|root,COG1853@2|Bacteria,1V52S@1239|Firmicutes,4HGD9@91061|Bacilli,279PY@186823|Alicyclobacillaceae	91061|Bacilli	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
CMS1_k127_753432_2	926550.CLDAP_35480	8.894e-08	61.0	COG3103@1|root,COG3693@1|root,COG3103@2|Bacteria,COG3693@2|Bacteria,COG4991@2|Bacteria,2GBGU@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase,Glyco_hydro_42
CMS1_k127_764881_2	382464.ABSI01000010_gene3498	3.791e-59	228.0	COG4225@1|root,COG4225@2|Bacteria	2|Bacteria	S	unsaturated chondroitin disaccharide hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	BNR_4
CMS1_k127_764881_5	1122169.AREN01000026_gene64	3.866e-05	57.0	COG3698@1|root,COG3698@2|Bacteria,1NM1P@1224|Proteobacteria,1SI38@1236|Gammaproteobacteria,1JD4Z@118969|Legionellales	118969|Legionellales	S	Phosphodiester glycosidase	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA
CMS1_k127_764881_4	1386089.N865_15070	4.296e-38	147.0	COG1832@1|root,COG1832@2|Bacteria,2IJYY@201174|Actinobacteria,4FJBB@85021|Intrasporangiaceae	201174|Actinobacteria	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
CMS1_k127_764881_3	1231185.BAMP01000038_gene1093	9.231e-50	189.0	COG0739@1|root,COG0739@2|Bacteria,1MXH6@1224|Proteobacteria,2U25J@28211|Alphaproteobacteria,43IWF@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CMS1_k127_764881_1	1121904.ARBP01000005_gene4829	5.908e-69	239.0	COG2193@1|root,COG2193@2|Bacteria,4NPMH@976|Bacteroidetes	976|Bacteroidetes	P	Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
CMS1_k127_764881_0	697281.Mahau_2319	1.418e-238	746.0	COG1486@1|root,COG1486@2|Bacteria,1TQ9I@1239|Firmicutes,24995@186801|Clostridia,42FX4@68295|Thermoanaerobacterales	186801|Clostridia	G	PFAM glycoside hydrolase, family 4	-	-	3.2.1.22	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_4,Glyco_hydro_4C
CMS1_k127_769754_0	879212.DespoDRAFT_02990	3.808e-119	397.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,42RS8@68525|delta/epsilon subdivisions,2WND0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Group II intron maturase-specific domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cas_Cas1,GIIM,RVT_1
CMS1_k127_779514_1	933262.AXAM01000083_gene767	3.721e-06	53.0	2CCKF@1|root,334IH@2|Bacteria,1NDED@1224|Proteobacteria,42VZE@68525|delta/epsilon subdivisions,2WRMN@28221|Deltaproteobacteria,2MM08@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_779514_0	1123518.ARWI01000001_gene1639	6.058e-59	216.0	COG2132@1|root,COG2132@2|Bacteria,1PM6Q@1224|Proteobacteria,1RRZJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_3
CMS1_k127_779626_0	215803.DB30_2436	4.331e-55	200.0	COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,42NGT@68525|delta/epsilon subdivisions,2WK3E@28221|Deltaproteobacteria,2YVIB@29|Myxococcales	28221|Deltaproteobacteria	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_1875	Ham1p_like
CMS1_k127_779626_4	313628.LNTAR_03974	1.64e-05	55.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
CMS1_k127_779626_2	313628.LNTAR_22919	7.994e-12	76.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,SBP_bac_10
CMS1_k127_779626_3	1142394.PSMK_04880	3.12e-10	73.0	COG2165@1|root,COG2165@2|Bacteria,2IY1V@203682|Planctomycetes	203682|Planctomycetes	NU	TIGRFAM prepilin-type N-terminal cleavage methylation domain	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CMS1_k127_779626_1	196162.Noca_3283	1.471e-44	167.0	COG0669@1|root,COG0669@2|Bacteria,2GN1S@201174|Actinobacteria,4DR12@85009|Propionibacteriales	201174|Actinobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016043,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0022607,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034214,GO:0034641,GO:0034654,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0055086,GO:0065003,GO:0070566,GO:0071704,GO:0071840,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
CMS1_k127_787490_0	530564.Psta_2420	2.225e-144	471.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_787490_1	1123242.JH636434_gene5340	0.0002483	50.0	COG1413@1|root,COG1413@2|Bacteria,2IZE1@203682|Planctomycetes	203682|Planctomycetes	C	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
CMS1_k127_78836_0	1366050.N234_09805	1.255e-136	459.0	COG1579@1|root,COG1579@2|Bacteria,1NR14@1224|Proteobacteria,2VZ72@28216|Betaproteobacteria,1KF11@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Zn-ribbon protein possibly nucleic acid-binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_798627_18	1303518.CCALI_00896	2.865e-12	70.0	COG3356@1|root,COG3356@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
CMS1_k127_798627_8	344747.PM8797T_18384	6.845e-108	363.0	COG0673@1|root,COG0673@2|Bacteria,2IWRC@203682|Planctomycetes	203682|Planctomycetes	S	COGs COG0673 dehydrogenase and related protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_798627_19	1280390.CBQR020000074_gene1594	9.902e-05	55.0	COG0477@1|root,COG2814@2|Bacteria,1V19N@1239|Firmicutes,4HDX3@91061|Bacilli,26TWU@186822|Paenibacillaceae	91061|Bacilli	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_798627_3	344747.PM8797T_04565	1.503e-138	453.0	COG0673@1|root,COG0673@2|Bacteria,2IXYP@203682|Planctomycetes	203682|Planctomycetes	S	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_798627_2	344747.PM8797T_19597	1.529e-155	510.0	COG3119@1|root,COG3119@2|Bacteria,2IXIU@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	3.1.6.8	ko:K01134	ko00600,ko04142,map00600,map04142	-	R04856	RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase,Sulfatase_C
CMS1_k127_798627_0	1123277.KB893244_gene5150	5.009e-200	648.0	COG3292@1|root,COG3292@2|Bacteria,4NF9I@976|Bacteroidetes,47MWU@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
CMS1_k127_798627_7	906968.Trebr_0251	8.509e-111	368.0	COG0039@1|root,COG0039@2|Bacteria,2J64G@203691|Spirochaetes	203691|Spirochaetes	C	Belongs to the LDH MDH superfamily. LDH family	ldh	-	1.1.1.27	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	-	R00703,R01000,R03104	RC00031,RC00044	ko00000,ko00001,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
CMS1_k127_798627_15	314345.SPV1_04598	5.133e-27	116.0	COG2913@1|root,COG2913@2|Bacteria,1N2JT@1224|Proteobacteria	1224|Proteobacteria	J	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SmpA_OmlA
CMS1_k127_798627_9	324602.Caur_3755	3.88e-91	334.0	COG0421@1|root,COG0421@2|Bacteria,2G80S@200795|Chloroflexi,37634@32061|Chloroflexia	32061|Chloroflexia	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_798627_16	879212.DespoDRAFT_03549	3.367e-18	87.0	COG1983@1|root,COG1983@2|Bacteria,1PWDN@1224|Proteobacteria,42TA8@68525|delta/epsilon subdivisions,2WPVU@28221|Deltaproteobacteria,2MKDS@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	PspC domain	pspC	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	PspC
CMS1_k127_798627_11	177437.HRM2_42190	2.898e-64	226.0	COG1842@1|root,COG1842@2|Bacteria,1NC7S@1224|Proteobacteria,42NMN@68525|delta/epsilon subdivisions,2WJJH@28221|Deltaproteobacteria,2MJDB@213118|Desulfobacterales	28221|Deltaproteobacteria	KT	PspA/IM30 family	-	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
CMS1_k127_798627_5	644282.Deba_2764	1.015e-123	406.0	COG3829@1|root,COG3829@2|Bacteria,1QUPP@1224|Proteobacteria,43BU3@68525|delta/epsilon subdivisions,2X751@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Sigma-54 interaction domain	-	-	-	ko:K03974	-	-	-	-	ko00000,ko03000	-	-	-	HTH_8,Sigma54_activat
CMS1_k127_798627_12	926556.Echvi_0404	6.404e-61	238.0	COG1649@1|root,COG1649@2|Bacteria	2|Bacteria	F	PFAM Uncharacterised BCR, COG1649	-	-	3.2.1.11,3.2.1.18,3.2.1.35,4.2.2.23	ko:K01186,ko:K01197,ko:K05988,ko:K11931,ko:K18197	ko00500,ko00511,ko00531,ko00600,ko01100,ko02026,ko04142,map00500,map00511,map00531,map00600,map01100,map02026,map04142	M00076,M00077	R04018,R07824,R07825,R10905,R11309	RC00028,RC00077	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	-	GH33,GH66,PL11	-	DUF1349,GHL10,Glyco_hydro_20b,Laminin_G_3,NAGidase,fn3
CMS1_k127_798627_6	671143.DAMO_0270	1.291e-114	394.0	COG1132@1|root,COG1132@2|Bacteria,2NNVD@2323|unclassified Bacteria	2|Bacteria	V	ABC transporter	msbA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0006869,GO:0008144,GO:0008150,GO:0008289,GO:0008559,GO:0009987,GO:0010876,GO:0015221,GO:0015238,GO:0015399,GO:0015405,GO:0015437,GO:0015893,GO:0015920,GO:0016020,GO:0016021,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0034040,GO:0034204,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042802,GO:0042908,GO:0042910,GO:0043167,GO:0043168,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0061024,GO:0065007,GO:0065008,GO:0071702,GO:0071840,GO:0071944,GO:0097035,GO:0097159,GO:0097367,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901265,GO:1901363,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	ko:K02021,ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21	-	iJN746.PP_4935,iPC815.YPO1395,iUMN146_1321.UM146_12980	ABC_membrane,ABC_tran
CMS1_k127_798627_14	234267.Acid_2809	1.364e-41	163.0	COG0566@1|root,COG0566@2|Bacteria,3Y3XM@57723|Acidobacteria	57723|Acidobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
CMS1_k127_798627_13	1453501.JELR01000002_gene1293	1.081e-58	226.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria	1224|Proteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	HEAT_2,Pkinase,TPR_8
CMS1_k127_798627_1	1123248.KB893381_gene946	5.379e-172	566.0	COG1073@1|root,COG1073@2|Bacteria,4NG6A@976|Bacteroidetes	976|Bacteroidetes	G	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	AXE1,BAAT_C,Hydrolase_4
CMS1_k127_798627_4	1046714.AMRX01000006_gene2362	3.021e-126	421.0	COG3119@1|root,COG3119@2|Bacteria,1RFP7@1224|Proteobacteria,1SJTS@1236|Gammaproteobacteria,469VM@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS1_k127_798627_10	1173028.ANKO01000153_gene5369	3.769e-76	264.0	COG3386@1|root,COG3386@2|Bacteria,1G05C@1117|Cyanobacteria,1H9TR@1150|Oscillatoriales	1117|Cyanobacteria	G	PFAM SMP-30 Gluconolaconase LRE-like region	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
CMS1_k127_806929_2	1121920.AUAU01000004_gene645	1.265e-103	340.0	COG0479@1|root,COG0479@2|Bacteria,3Y3XR@57723|Acidobacteria	57723|Acidobacteria	C	2Fe-2S iron-sulfur cluster binding domain	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_7,Fer4_8
CMS1_k127_806929_3	378806.STAUR_0249	1.294e-21	108.0	COG2885@1|root,COG2885@2|Bacteria,1R4CA@1224|Proteobacteria,42RIU@68525|delta/epsilon subdivisions,2WNC0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4892,OmpA
CMS1_k127_806929_0	1379698.RBG1_1C00001G0788	5.473e-192	618.0	COG1960@1|root,COG1960@2|Bacteria,2NNRN@2323|unclassified Bacteria	2|Bacteria	I	Dehydrogenase	fadE10	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,DUF1974
CMS1_k127_806929_1	1379698.RBG1_1C00001G0788	5.72e-119	394.0	COG1960@1|root,COG1960@2|Bacteria,2NNRN@2323|unclassified Bacteria	2|Bacteria	I	Dehydrogenase	fadE10	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,DUF1974
CMS1_k127_81282_0	1123508.JH636451_gene5949	5.676e-15	83.0	COG4886@1|root,COG4886@2|Bacteria,2J2ZP@203682|Planctomycetes	203682|Planctomycetes	S	Leucine Rich repeat	-	-	-	-	-	-	-	-	-	-	-	-	LRR_6
CMS1_k127_81282_1	338966.Ppro_2579	0.0007844	42.0	2ANJH@1|root,31DIJ@2|Bacteria,1P4XW@1224|Proteobacteria	1224|Proteobacteria	S	PEP-CTERM motif	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
CMS1_k127_817473_1	290397.Adeh_2766	8.164e-60	228.0	COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,42MZY@68525|delta/epsilon subdivisions,2WJWT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
CMS1_k127_817473_0	700508.D174_24385	5.662e-150	486.0	COG1004@1|root,COG1004@2|Bacteria,2GJQB@201174|Actinobacteria,235P0@1762|Mycobacteriaceae	201174|Actinobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	algD	-	1.1.1.132	ko:K00066	ko00051,ko00520,ko02020,map00051,map00520,map02020	-	R00880	RC00291	ko00000,ko00001,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
CMS1_k127_819098_2	1158610.UC3_01927	0.0004207	45.0	COG0344@1|root,COG0344@2|Bacteria,1V2QT@1239|Firmicutes,4HGFI@91061|Bacilli,4B6RY@81852|Enterococcaceae	91061|Bacilli	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
CMS1_k127_819098_1	1379270.AUXF01000001_gene2759	8.908e-15	89.0	COG1595@1|root,COG1595@2|Bacteria,1ZUGG@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_819098_0	1303518.CCALI_01897	2.539e-17	89.0	COG1595@1|root,COG1595@2|Bacteria	1303518.CCALI_01897|-	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	-
CMS1_k127_830612_22	768671.ThimaDRAFT_4800	1.559e-15	86.0	COG2426@1|root,COG2426@2|Bacteria,1N9Q5@1224|Proteobacteria,1SQIQ@1236|Gammaproteobacteria,1X11G@135613|Chromatiales	135613|Chromatiales	S	Putative small multi-drug export protein	-	-	-	-	-	-	-	-	-	-	-	-	Sm_multidrug_ex
CMS1_k127_830612_14	1122919.KB905560_gene1481	1.087e-41	164.0	COG0666@1|root,COG0666@2|Bacteria,1V657@1239|Firmicutes,4HIDE@91061|Bacilli,26WY6@186822|Paenibacillaceae	91061|Bacilli	S	Ankyrin repeat	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_4,Ank_5
CMS1_k127_830612_17	1123508.JH636448_gene7570	1.828e-32	130.0	COG3682@1|root,COG3682@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
CMS1_k127_830612_23	1123508.JH636443_gene4728	2.373e-09	67.0	COG4219@1|root,COG4219@2|Bacteria,2J24Z@203682|Planctomycetes	203682|Planctomycetes	KT	Antirepressor regulating drug resistance	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
CMS1_k127_830612_11	614083.AWQR01000013_gene1668	3.122e-69	245.0	COG0300@1|root,COG0300@2|Bacteria,1RGKZ@1224|Proteobacteria,2WGI9@28216|Betaproteobacteria,4ADU3@80864|Comamonadaceae	28216|Betaproteobacteria	S	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS1_k127_830612_9	313628.LNTAR_04741	8.382e-80	272.0	COG0603@1|root,COG0603@2|Bacteria	2|Bacteria	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
CMS1_k127_830612_24	1033732.CAHI01000003_gene2316	4.046e-09	68.0	2DB9J@1|root,2Z7X1@2|Bacteria,4NGUY@976|Bacteroidetes,2FQG2@200643|Bacteroidia	976|Bacteroidetes	S	Domain of unknown function (DUF5109)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4434,DUF5109
CMS1_k127_830612_16	640081.Dsui_1888	3.919e-33	140.0	COG1639@1|root,COG1639@2|Bacteria,1RCW6@1224|Proteobacteria,2VMUW@28216|Betaproteobacteria,2KZT6@206389|Rhodocyclales	206389|Rhodocyclales	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
CMS1_k127_830612_7	1232410.KI421414_gene2855	1.245e-96	325.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,42MRN@68525|delta/epsilon subdivisions,2WJCH@28221|Deltaproteobacteria,43T7C@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Polysaccharide biosynthesis protein	-	-	5.1.3.2,5.1.3.7	ko:K01784,ko:K02473	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R00418,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
CMS1_k127_830612_18	44251.PDUR_08850	3.068e-29	130.0	COG0673@1|root,COG0673@2|Bacteria,1VAKD@1239|Firmicutes,4IPNF@91061|Bacilli,2760T@186822|Paenibacillaceae	91061|Bacilli	S	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_830612_10	1396141.BATP01000060_gene4642	5.934e-77	271.0	COG0592@1|root,COG0592@2|Bacteria,46SPK@74201|Verrucomicrobia,2ITMH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	-	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
CMS1_k127_830612_3	1499967.BAYZ01000014_gene6369	2.43e-133	449.0	COG2804@1|root,COG2804@2|Bacteria,2NNNI@2323|unclassified Bacteria	2|Bacteria	NU	Type II secretion system (T2SS), protein E, N-terminal domain	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
CMS1_k127_830612_19	1215092.PA6_002_00780	6.465e-27	125.0	COG5563@1|root,COG5563@2|Bacteria,1R9G5@1224|Proteobacteria	1224|Proteobacteria	M	HAF family	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
CMS1_k127_830612_2	1499967.BAYZ01000157_gene595	1.879e-142	467.0	COG2270@1|root,COG2270@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	MFS_1
CMS1_k127_830612_0	1304875.JAFZ01000001_gene1136	9.288e-290	913.0	COG1217@1|root,COG1217@2|Bacteria,3T9TF@508458|Synergistetes	508458|Synergistetes	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
CMS1_k127_830612_8	1403819.BATR01000125_gene4449	5.509e-80	280.0	2CEMG@1|root,346QA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
CMS1_k127_830612_5	1218084.BBJK01000152_gene7607	9.554e-111	366.0	COG1028@1|root,COG1028@2|Bacteria,1PFUB@1224|Proteobacteria,2VP9J@28216|Betaproteobacteria,1K7UG@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS1_k127_830612_13	247490.KSU1_C0795	5.491e-51	194.0	COG0859@1|root,COG0859@2|Bacteria,2IYZS@203682|Planctomycetes	203682|Planctomycetes	M	COG0859 ADP-heptose LPS heptosyltransferase	-	-	-	ko:K02841,ko:K02849	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
CMS1_k127_830612_20	1121430.JMLG01000012_gene2018	4.374e-23	102.0	COG2250@1|root,COG2250@2|Bacteria,1VNW7@1239|Firmicutes,24WXS@186801|Clostridia	186801|Clostridia	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
CMS1_k127_830612_6	935948.KE386495_gene1292	1.719e-100	359.0	COG1175@1|root,COG1175@2|Bacteria,1TPTZ@1239|Firmicutes,2492R@186801|Clostridia,42JBI@68295|Thermoanaerobacterales	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_830612_12	697281.Mahau_0771	1.884e-65	252.0	COG0395@1|root,COG0395@2|Bacteria,1TSAB@1239|Firmicutes,25C5T@186801|Clostridia,42JEU@68295|Thermoanaerobacterales	186801|Clostridia	P	COGs COG0395 ABC-type sugar transport system permease component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_830612_21	1300345.LF41_3149	1.036e-17	91.0	COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,1RMRZ@1236|Gammaproteobacteria,1X4ZH@135614|Xanthomonadales	135614|Xanthomonadales	J	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
CMS1_k127_830612_4	398767.Glov_2464	4.128e-124	409.0	COG3635@1|root,COG3635@2|Bacteria,1R4TM@1224|Proteobacteria,42NCT@68525|delta/epsilon subdivisions,2WKEG@28221|Deltaproteobacteria,43SUK@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Proposed homoserine kinase	apgM	-	5.4.2.12	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,PhosphMutase
CMS1_k127_830612_1	289376.THEYE_A0785	3.097e-176	567.0	COG0119@1|root,COG0119@2|Bacteria,3J0DC@40117|Nitrospirae	40117|Nitrospirae	E	Belongs to the alpha-IPM synthase homocitrate synthase family	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
CMS1_k127_830612_25	1121356.AQUW01000006_gene2072	4.603e-06	51.0	COG1226@1|root,COG1226@2|Bacteria,2GKB8@201174|Actinobacteria,22KRZ@1653|Corynebacteriaceae	201174|Actinobacteria	P	Kef-type K transport systems	kch	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_N
CMS1_k127_837564_14	234267.Acid_0211	2.722e-24	116.0	COG3119@1|root,COG3119@2|Bacteria,3Y2QE@57723|Acidobacteria	57723|Acidobacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_837564_13	1239962.C943_03015	1.165e-29	123.0	COG2755@1|root,COG2755@2|Bacteria,4NQAK@976|Bacteroidetes,47QQ7@768503|Cytophagia	976|Bacteroidetes	E	Stress responsive A/B Barrel Domain	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
CMS1_k127_837564_9	1307759.JOMJ01000003_gene2354	3.694e-51	207.0	COG1538@1|root,COG1538@2|Bacteria,1PCPQ@1224|Proteobacteria,42PU9@68525|delta/epsilon subdivisions,2WU8U@28221|Deltaproteobacteria,2M8K7@213115|Desulfovibrionales	28221|Deltaproteobacteria	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
CMS1_k127_837564_0	237368.SCABRO_01551	0.0	1842.0	COG3696@1|root,COG3696@2|Bacteria,2IX94@203682|Planctomycetes	203682|Planctomycetes	P	AcrB/AcrD/AcrF family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
CMS1_k127_837564_2	595460.RRSWK_02559	8.569e-201	654.0	COG0845@1|root,COG0845@2|Bacteria,2IZ22@203682|Planctomycetes	203682|Planctomycetes	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	DUF3347,HlyD_D23
CMS1_k127_837564_6	1280380.KR100_02940	1.622e-95	327.0	COG4148@1|root,COG4148@2|Bacteria	2|Bacteria	P	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system	modC	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,TOBE
CMS1_k127_837564_8	745277.GRAQ_02182	1.927e-67	236.0	COG4149@1|root,COG4149@2|Bacteria,1MUXR@1224|Proteobacteria,1RRDV@1236|Gammaproteobacteria,3FEMX@34037|Rahnella	1236|Gammaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	modB	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	iECO103_1326.ECO103_0752	BPD_transp_1
CMS1_k127_837564_10	1280380.KR100_02930	5.184e-51	191.0	COG0725@1|root,COG0725@2|Bacteria,1G0VZ@1117|Cyanobacteria,1H0C9@1129|Synechococcus	1117|Cyanobacteria	P	ABC transporter, periplasmic molybdate-binding protein	modA	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	iJN678.modA	SBP_bac_11
CMS1_k127_837564_3	485913.Krac_5920	6.453e-169	541.0	COG0641@1|root,COG0641@2|Bacteria,2G74V@200795|Chloroflexi	200795|Chloroflexi	C	Iron-sulfur cluster-binding domain	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Radical_SAM,SPASM
CMS1_k127_837564_12	1232410.KI421424_gene1841	1.188e-34	136.0	COG1403@1|root,COG1403@2|Bacteria,1RGZQ@1224|Proteobacteria,42REM@68525|delta/epsilon subdivisions,2WNMG@28221|Deltaproteobacteria,43SKP@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH
CMS1_k127_837564_7	118173.KB235914_gene303	2.539e-78	270.0	COG2846@1|root,COG2846@2|Bacteria,1GBB9@1117|Cyanobacteria	1117|Cyanobacteria	D	Di-iron-containing protein involved in the repair of iron-sulfur clusters	-	-	-	ko:K07322	-	-	-	-	ko00000	-	-	-	Hemerythrin,ScdA_N
CMS1_k127_837564_16	1237149.C900_01467	3.052e-06	51.0	COG3256@1|root,COG3256@2|Bacteria,4NG9H@976|Bacteroidetes,47K63@768503|Cytophagia	976|Bacteroidetes	P	Cytochrome C and Quinol oxidase polypeptide I	-	-	1.7.2.5	ko:K04561	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002,ko01000	3.D.4.10	-	-	COX1
CMS1_k127_837564_5	1906.SFRA_20540	5.918e-98	344.0	arCOG02075@1|root,33AGA@2|Bacteria	2|Bacteria	S	NnrS protein	-	-	-	-	-	-	-	-	-	-	-	-	NnrS
CMS1_k127_837564_11	1232410.KI421426_gene1437	8.701e-46	173.0	arCOG11509@1|root,31KIR@2|Bacteria,1RGVE@1224|Proteobacteria,42T74@68525|delta/epsilon subdivisions,2WPQ8@28221|Deltaproteobacteria,43UQJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_837564_15	984262.SGRA_2114	1.093e-21	104.0	COG1959@1|root,COG1959@2|Bacteria,4NQGU@976|Bacteroidetes,1ISW6@117747|Sphingobacteriia	976|Bacteroidetes	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
CMS1_k127_837564_1	243090.RB8254	7.811e-243	771.0	COG0531@1|root,COG0589@1|root,COG0531@2|Bacteria,COG0589@2|Bacteria,2J0UK@203682|Planctomycetes	203682|Planctomycetes	E	Amino acid permease	-	-	-	ko:K16238	-	-	-	-	ko00000,ko02000	2.A.3.5	-	-	AA_permease_2
CMS1_k127_837564_4	760192.Halhy_3573	5.855e-167	548.0	COG4225@1|root,COG4225@2|Bacteria,4NF1N@976|Bacteroidetes,1IP96@117747|Sphingobacteriia	976|Bacteroidetes	S	PFAM Heparinase II III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4962,Hepar_II_III
CMS1_k127_840352_0	768671.ThimaDRAFT_4354	1.397e-50	184.0	COG0137@1|root,COG1948@1|root,COG0137@2|Bacteria,COG1948@2|Bacteria,1MV0Y@1224|Proteobacteria,1RMEC@1236|Gammaproteobacteria,1WXPT@135613|Chromatiales	135613|Chromatiales	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
CMS1_k127_840352_3	264201.pc1018	1.334e-14	80.0	COG2944@1|root,COG2944@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	ko:K07726	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3,HTH_31
CMS1_k127_840352_2	384676.PSEEN4321	8.821e-21	96.0	COG4737@1|root,COG4737@2|Bacteria,1N7N5@1224|Proteobacteria,1S6BG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Cytotoxic translational repressor of toxin-antitoxin stability system	-	-	-	-	-	-	-	-	-	-	-	-	RelE
CMS1_k127_840352_4	1174528.JH992898_gene2021	3.749e-05	51.0	COG0457@1|root,COG3206@1|root,COG0457@2|Bacteria,COG3206@2|Bacteria,1G1U5@1117|Cyanobacteria,1JHI2@1189|Stigonemataceae	1117|Cyanobacteria	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
CMS1_k127_840352_1	497964.CfE428DRAFT_0725	1.613e-31	135.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
CMS1_k127_844833_1	344747.PM8797T_14434	1.763e-164	534.0	COG1506@1|root,COG1506@2|Bacteria,2IYE5@203682|Planctomycetes	203682|Planctomycetes	E	COG1073 Hydrolases of the alpha beta superfamily	-	-	-	-	-	-	-	-	-	-	-	-	AXE1
CMS1_k127_844833_2	1232410.KI421415_gene2974	7.529e-145	477.0	COG2170@1|root,COG2170@2|Bacteria,1MY35@1224|Proteobacteria,42PBG@68525|delta/epsilon subdivisions,2WK4S@28221|Deltaproteobacteria,43UJW@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Glutamate-cysteine ligase family 2(GCS2)	-	-	-	-	-	-	-	-	-	-	-	-	GCS2
CMS1_k127_844833_0	1232410.KI421415_gene2975	1.531e-197	627.0	COG0189@1|root,COG0189@2|Bacteria,1MX5X@1224|Proteobacteria,42MPG@68525|delta/epsilon subdivisions,2WKW8@28221|Deltaproteobacteria,43UK8@69541|Desulfuromonadales	28221|Deltaproteobacteria	HJ	RimK-like ATPgrasp N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Dala_Dala_lig_C,RLAN,RimK
CMS1_k127_844833_5	765952.PUV_08470	1.832e-83	284.0	COG3271@1|root,COG3271@2|Bacteria,2JGZU@204428|Chlamydiae	204428|Chlamydiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_844833_6	1267535.KB906767_gene1026	1.966e-66	245.0	COG0673@1|root,COG0673@2|Bacteria,3Y6VS@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_844833_3	886293.Sinac_1008	1.337e-85	300.0	COG0673@1|root,COG0673@2|Bacteria,2IX39@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_844833_8	929558.SMGD1_1530	5.197e-36	145.0	COG0546@1|root,COG0546@2|Bacteria,1RBMZ@1224|Proteobacteria,42RG3@68525|delta/epsilon subdivisions,2YP44@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Hydrolase	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
CMS1_k127_844833_7	521674.Plim_1759	3.747e-63	223.0	COG0299@1|root,COG0299@2|Bacteria,2IZ96@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
CMS1_k127_844833_9	1048983.EL17_12215	5.499e-16	79.0	COG1983@1|root,COG1983@2|Bacteria,4NWKE@976|Bacteroidetes,47SK6@768503|Cytophagia	976|Bacteroidetes	KT	PspC domain	pspC	-	-	-	-	-	-	-	-	-	-	-	PspC
CMS1_k127_844833_4	574087.Acear_1859	1.478e-85	291.0	COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,24AGY@186801|Clostridia,3WBB0@53433|Halanaerobiales	186801|Clostridia	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
CMS1_k127_865402_0	1267535.KB906767_gene1129	4.789e-31	138.0	COG0515@1|root,COG0515@2|Bacteria,3Y4IC@57723|Acidobacteria,2JJ7M@204432|Acidobacteriia	204432|Acidobacteriia	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS1_k127_865402_2	1463857.JOFZ01000001_gene5704	1.184e-07	64.0	COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_865402_1	84531.JMTZ01000074_gene2084	6.872e-18	99.0	COG1595@1|root,COG1595@2|Bacteria,1RCMS@1224|Proteobacteria,1S55Z@1236|Gammaproteobacteria,1X59U@135614|Xanthomonadales	135614|Xanthomonadales	K	RNA polymerase sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_868422_5	314230.DSM3645_28142	4.579e-14	76.0	COG3316@1|root,COG3316@2|Bacteria,2J4XX@203682|Planctomycetes	203682|Planctomycetes	L	IS66 C-terminal element	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
CMS1_k127_868422_2	204669.Acid345_2824	1.439e-88	306.0	COG0644@1|root,COG0644@2|Bacteria,3Y4BQ@57723|Acidobacteria,2JJ6H@204432|Acidobacteriia	204432|Acidobacteriia	C	NAD(P)-binding Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
CMS1_k127_868422_4	1288494.EBAPG3_17800	4.638e-19	96.0	COG2867@1|root,COG2867@2|Bacteria,1NCZA@1224|Proteobacteria,2WBH8@28216|Betaproteobacteria,3734A@32003|Nitrosomonadales	28216|Betaproteobacteria	I	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
CMS1_k127_868422_0	886293.Sinac_0668	7.97e-168	538.0	COG0399@1|root,COG0399@2|Bacteria	2|Bacteria	E	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
CMS1_k127_868422_3	575540.Isop_2135	7.791e-21	104.0	COG1082@1|root,COG1082@2|Bacteria,2IZ6T@203682|Planctomycetes	203682|Planctomycetes	G	Sugar phosphate	-	-	4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
CMS1_k127_868422_1	1267535.KB906767_gene1671	2.526e-116	391.0	COG0591@1|root,COG0591@2|Bacteria	2|Bacteria	E	symporter activity	-	-	-	-	-	-	-	-	-	-	-	-	SSF
CMS1_k127_886533_1	373903.Hore_09660	1.308e-129	457.0	COG2373@1|root,COG2373@2|Bacteria	2|Bacteria	U	Large extracellular alpha-helical protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,MG1,Thiol-ester_cl
CMS1_k127_886533_2	643562.Daes_3263	2.017e-122	421.0	COG4953@1|root,COG4953@2|Bacteria,1MUA9@1224|Proteobacteria,42MSV@68525|delta/epsilon subdivisions,2WJ6U@28221|Deltaproteobacteria,2M8X8@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM glycosyl transferase family 51	pbpC	-	2.4.1.129	ko:K05367	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	BiPBP_C,Transgly,Transpeptidase
CMS1_k127_886533_0	1121904.ARBP01000042_gene4905	6.034e-226	725.0	COG3292@1|root,COG3292@2|Bacteria,4NF9I@976|Bacteroidetes,47XHD@768503|Cytophagia	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop
CMS1_k127_886533_7	215803.DB30_5906	5.253e-41	162.0	COG5429@1|root,COG5429@2|Bacteria,1MW6R@1224|Proteobacteria,43513@68525|delta/epsilon subdivisions,2X944@28221|Deltaproteobacteria,2Z1T3@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1223)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1223
CMS1_k127_886533_5	269797.Mbar_A2583	4.536e-50	187.0	COG1280@1|root,arCOG01948@2157|Archaea,2XWP7@28890|Euryarchaeota,2NAHG@224756|Methanomicrobia	224756|Methanomicrobia	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	iAF692.Mbar_A2583	LysE
CMS1_k127_886533_6	313628.LNTAR_08584	6.855e-42	177.0	COG1196@1|root,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	sca1	-	-	-	-	-	-	-	-	-	-	-	DUF4114,Phage_HK97_TLTM,SLT,TMP_2,Tape_meas_lam_C
CMS1_k127_886533_3	319225.Plut_1389	6.115e-74	276.0	COG3063@1|root,COG3063@2|Bacteria	2|Bacteria	NU	photosynthesis	-	-	-	ko:K02453,ko:K20543	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	1.B.55.3,3.A.15	-	-	TPR_12,TPR_16,TPR_19,TPR_2,TPR_7,TPR_8,Transglut_core
CMS1_k127_886533_4	1121904.ARBP01000013_gene358	7.098e-51	202.0	COG4886@1|root,COG4886@2|Bacteria,4NFES@976|Bacteroidetes,47MG0@768503|Cytophagia	976|Bacteroidetes	S	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	LRR_8,PSCyt1
CMS1_k127_886533_8	1123242.JH636434_gene3346	8.058e-27	127.0	COG2010@1|root,COG2010@2|Bacteria,2IXJ6@203682|Planctomycetes	203682|Planctomycetes	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,PSCyt2,PSD1
CMS1_k127_888854_1	234267.Acid_3365	2.208e-81	276.0	COG4312@1|root,COG4312@2|Bacteria,3Y4MZ@57723|Acidobacteria	57723|Acidobacteria	S	Bacterial protein of unknown function (DUF899)	-	-	-	-	-	-	-	-	-	-	-	-	DUF899
CMS1_k127_888854_0	344747.PM8797T_19071	4.614e-113	379.0	COG0673@1|root,COG0673@2|Bacteria,2IX5C@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_888854_2	1121937.AUHJ01000004_gene1125	5.343e-49	184.0	COG0300@1|root,COG0300@2|Bacteria,1RG9T@1224|Proteobacteria,1S48Y@1236|Gammaproteobacteria,467A1@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	KR domain	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
CMS1_k127_89444_0	870187.Thini_1183	2.241e-251	776.0	COG1850@1|root,COG1850@2|Bacteria,1MWEB@1224|Proteobacteria,1RRMX@1236|Gammaproteobacteria,4604Y@72273|Thiotrichales	72273|Thiotrichales	G	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site	cbbL	-	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
CMS1_k127_89444_1	314345.SPV1_12792	2.549e-164	520.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria	1224|Proteobacteria	K	Transcriptional regulator	-	-	-	ko:K21703	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
CMS1_k127_906840_0	1303518.CCALI_00634	0.0	1193.0	28K2K@1|root,2Z9RX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_906840_8	1123366.TH3_19772	1.426e-54	201.0	COG0310@1|root,COG0310@2|Bacteria,1RJRC@1224|Proteobacteria,2TT2G@28211|Alphaproteobacteria,2JSTV@204441|Rhodospirillales	204441|Rhodospirillales	P	COG0310 ABC-type Co2 transport system, permease component	-	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM
CMS1_k127_906840_10	1316936.K678_06260	2.394e-24	110.0	COG2373@1|root,COG2373@2|Bacteria,1QUMU@1224|Proteobacteria,2TZM8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_906840_9	1120956.JHZK01000004_gene1312	5.786e-48	184.0	COG0619@1|root,COG0619@2|Bacteria,1RJIT@1224|Proteobacteria,2U11T@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	COG0619 ABC-type cobalt transport system, permease component CbiQ and related transporters	cbiQ	-	-	ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
CMS1_k127_906840_6	648757.Rvan_0046	4.623e-82	280.0	COG1122@1|root,COG1122@2|Bacteria,1QN6E@1224|Proteobacteria,2U5NI@28211|Alphaproteobacteria,3N8BQ@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02006	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	ABC_tran
CMS1_k127_906840_2	616991.JPOO01000003_gene2365	2.247e-126	418.0	COG0399@1|root,COG0399@2|Bacteria,4NG9W@976|Bacteroidetes,1HZDU@117743|Flavobacteriia,23H42@178469|Arenibacter	976|Bacteroidetes	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
CMS1_k127_906840_7	1140.Synpcc7942_0242	6.751e-71	252.0	COG0530@1|root,COG0530@2|Bacteria,1G1Y9@1117|Cyanobacteria,1GYEM@1129|Synechococcus	1117|Cyanobacteria	P	COG0530 Ca2 Na antiporter	ecm27	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
CMS1_k127_906840_4	1035308.AQYY01000001_gene2157	2.856e-101	338.0	COG1045@1|root,COG1045@2|Bacteria,1TR42@1239|Firmicutes,249SF@186801|Clostridia,25ZYK@186807|Peptococcaceae	186801|Clostridia	E	TIGRFAM Serine O-acetyltransferase	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
CMS1_k127_906840_3	933262.AXAM01000098_gene3457	1.003e-105	364.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,42MVQ@68525|delta/epsilon subdivisions,2WMS6@28221|Deltaproteobacteria,2MNJX@213118|Desulfobacterales	28221|Deltaproteobacteria	CO	Cytochrome C biogenesis protein transmembrane region	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
CMS1_k127_906840_11	1267533.KB906733_gene3029	3.943e-11	76.0	COG4232@1|root,COG4232@2|Bacteria,3Y5QG@57723|Acidobacteria,2JK1Z@204432|Acidobacteriia	204432|Acidobacteriia	CO	Disulphide bond corrector protein DsbC	-	-	-	-	-	-	-	-	-	-	-	-	DsbC
CMS1_k127_906840_1	1382306.JNIM01000001_gene466	1.514e-221	712.0	COG1331@1|root,COG1331@2|Bacteria,2G5R1@200795|Chloroflexi	200795|Chloroflexi	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
CMS1_k127_906840_5	761193.Runsl_0709	8.972e-96	319.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS1_k127_906840_12	452637.Oter_0296	4.651e-05	54.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	ko:K16648,ko:K20444	-	-	-	-	ko00000,ko01000,ko01003,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_tranf_2_3,Glycos_transf_2,Methyltransf_11,NTP_transf_5
CMS1_k127_918524_1	1123242.JH636435_gene1380	6.221e-288	897.0	COG0365@1|root,COG0365@2|Bacteria,2IX5P@203682|Planctomycetes	203682|Planctomycetes	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
CMS1_k127_918524_9	596151.DesfrDRAFT_1153	1.404e-37	153.0	COG0607@1|root,COG0607@2|Bacteria,1NPYY@1224|Proteobacteria,42XNF@68525|delta/epsilon subdivisions,2WTBJ@28221|Deltaproteobacteria,2MBWE@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CMS1_k127_918524_6	378806.STAUR_7130	9.203e-55	204.0	COG1912@1|root,COG1912@2|Bacteria,1MV99@1224|Proteobacteria,42SHG@68525|delta/epsilon subdivisions,2WP1D@28221|Deltaproteobacteria,2YYNU@29|Myxococcales	28221|Deltaproteobacteria	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
CMS1_k127_918524_3	671143.DAMO_2061	5.264e-67	235.0	COG2231@1|root,COG2231@2|Bacteria,2NR9H@2323|unclassified Bacteria	2|Bacteria	L	endonuclease III	magIII	-	-	ko:K07457	-	-	-	-	ko00000	-	-	-	HhH-GPD
CMS1_k127_918524_8	1131269.AQVV01000005_gene376	3.905e-42	170.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
CMS1_k127_918524_2	479434.Sthe_2893	6.672e-72	253.0	COG0524@1|root,COG0524@2|Bacteria,2G6JH@200795|Chloroflexi,27YEN@189775|Thermomicrobia	189775|Thermomicrobia	H	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
CMS1_k127_918524_4	293826.Amet_2777	2.512e-57	207.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,248AR@186801|Clostridia,36EV9@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
CMS1_k127_918524_10	469383.Cwoe_3048	8.323e-37	145.0	COG1437@1|root,COG1437@2|Bacteria,2I6ID@201174|Actinobacteria,4CQCZ@84995|Rubrobacteria	84995|Rubrobacteria	F	CYTH	-	-	-	-	-	-	-	-	-	-	-	-	CYTH
CMS1_k127_918524_0	1278073.MYSTI_07508	2.337e-292	932.0	COG3391@1|root,COG3391@2|Bacteria,1R66T@1224|Proteobacteria	1224|Proteobacteria	C	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
CMS1_k127_918524_5	234267.Acid_6183	2.244e-55	211.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS1_k127_918524_12	663278.Ethha_0123	0.0001479	55.0	COG0457@1|root,COG0463@1|root,COG0457@2|Bacteria,COG0463@2|Bacteria,1TSF5@1239|Firmicutes,25B5G@186801|Clostridia,3WKBY@541000|Ruminococcaceae	186801|Clostridia	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,TPR_1,TPR_16,TPR_2,TPR_8
CMS1_k127_918524_11	446462.Amir_4949	5.54e-07	62.0	COG1215@1|root,COG1215@2|Bacteria,2GJZI@201174|Actinobacteria,4DZ72@85010|Pseudonocardiales	201174|Actinobacteria	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glyco_transf_21,Glycos_transf_2
CMS1_k127_919022_0	926550.CLDAP_28350	9.776e-10	70.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Collagen,G5,Gln_amidase,Gram_pos_anchor,YSIRK_signal,YadA_stalk
CMS1_k127_919022_1	1429851.X548_12015	0.0002943	51.0	COG4235@1|root,COG4235@2|Bacteria,1MY4J@1224|Proteobacteria,1RZEA@1236|Gammaproteobacteria,1X3KB@135614|Xanthomonadales	135614|Xanthomonadales	O	Cytochrome C biogenesis	cycH	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	TPR_16,TPR_19,TPR_2
CMS1_k127_929805_0	1122933.JNIY01000003_gene473	1.653e-09	71.0	COG3661@1|root,COG3661@2|Bacteria,2ID53@201174|Actinobacteria,4F22A@85016|Cellulomonadaceae	201174|Actinobacteria	G	Glycosyl hydrolase family 67 C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_67C
CMS1_k127_934859_1	411479.BACUNI_03969	1.864e-08	59.0	COG4733@1|root,COG4733@2|Bacteria,4NKP8@976|Bacteroidetes,2FPJ8@200643|Bacteroidia,4AQCK@815|Bacteroidaceae	976|Bacteroidetes	S	COG NOG11699 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
CMS1_k127_935194_3	1125863.JAFN01000001_gene702	0.0004426	50.0	COG3334@1|root,COG3334@2|Bacteria	2|Bacteria	S	PFAM MgtE intracellular	ylxF	-	-	ko:K02383	-	-	-	-	ko00000,ko02035	-	-	-	MgtE_N
CMS1_k127_935194_1	635013.TherJR_1541	1.477e-107	358.0	COG1536@1|root,COG1536@2|Bacteria,1TP01@1239|Firmicutes,2480B@186801|Clostridia,260SV@186807|Peptococcaceae	186801|Clostridia	N	flagellar motor switch protein FliG	fliG	-	-	ko:K02410	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliG_C,FliG_M,FliG_N
CMS1_k127_935194_2	391735.Veis_1113	9.819e-18	97.0	COG1766@1|root,COG1766@2|Bacteria,1MUQR@1224|Proteobacteria,2VI9M@28216|Betaproteobacteria,4A9WH@80864|Comamonadaceae	28216|Betaproteobacteria	N	The M ring may be actively involved in energy transduction	fliF	-	-	ko:K02409	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	YscJ_FliF,YscJ_FliF_C
CMS1_k127_935194_0	1232410.KI421428_gene1119	1.686e-131	437.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria,43UDA@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	PFAM peptidase S1 and S6, chymotrypsin Hap	degP	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
CMS1_k127_935822_5	1250278.JQNQ01000001_gene3151	0.0001958	47.0	COG0457@1|root,COG0457@2|Bacteria,4NJN9@976|Bacteroidetes,1HY86@117743|Flavobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
CMS1_k127_935822_1	929562.Emtol_0543	1.868e-166	554.0	COG2366@1|root,COG2366@2|Bacteria,4NEIX@976|Bacteroidetes,47KXN@768503|Cytophagia	976|Bacteroidetes	S	Penicillin amidase	pac	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
CMS1_k127_935822_4	886293.Sinac_6975	1.591e-05	57.0	28KPG@1|root,2ZA7K@2|Bacteria,2J1E2@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_935822_0	439497.RR11_967	3.487e-188	601.0	COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,2TSZY@28211|Alphaproteobacteria,4NAS0@97050|Ruegeria	28211|Alphaproteobacteria	C	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
CMS1_k127_935822_2	204669.Acid345_4700	6.07e-58	207.0	COG1611@1|root,COG1611@2|Bacteria,3Y4RU@57723|Acidobacteria,2JJDD@204432|Acidobacteriia	204432|Acidobacteriia	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
CMS1_k127_935822_3	331635.G5S_0052	1.059e-11	64.0	COG0208@1|root,COG0208@2|Bacteria,2JFH1@204428|Chlamydiae	204428|Chlamydiae	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdB	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
CMS1_k127_950134_0	502025.Hoch_4658	7.999e-166	542.0	COG1858@1|root,COG3420@1|root,COG1858@2|Bacteria,COG3420@2|Bacteria,1MV70@1224|Proteobacteria,42ZVA@68525|delta/epsilon subdivisions,2WVEX@28221|Deltaproteobacteria,2YU4Z@29|Myxococcales	28221|Deltaproteobacteria	C	cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG
CMS1_k127_951593_1	1123242.JH636434_gene5158	1.049e-36	142.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2
CMS1_k127_951593_0	1304284.L21TH_0179	1.492e-218	689.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,247W7@186801|Clostridia,36HQZ@31979|Clostridiaceae	186801|Clostridia	C	Aldehyde dehydrogenase family	rocA	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh,Pro_dh
CMS1_k127_955836_0	1333523.L593_05995	2.956e-38	149.0	COG1063@1|root,arCOG01621@2157|Archaea,2XTZT@28890|Euryarchaeota,23SIP@183963|Halobacteria	183963|Halobacteria	E	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N
CMS1_k127_955836_3	1123517.JOMR01000001_gene375	5.288e-15	83.0	COG1309@1|root,COG1309@2|Bacteria,1RG05@1224|Proteobacteria,1S7XG@1236|Gammaproteobacteria,461E2@72273|Thiotrichales	72273|Thiotrichales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_10,TetR_N
CMS1_k127_955836_2	247490.KSU1_C1333	4.441e-16	90.0	COG4968@1|root,COG4968@2|Bacteria,2J519@203682|Planctomycetes	203682|Planctomycetes	NU	Pfam:N_methyl_2	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl,SBP_bac_10
CMS1_k127_968818_0	338963.Pcar_1381	6.214e-142	457.0	COG2801@1|root,COG2801@2|Bacteria,1MZ45@1224|Proteobacteria,42MM6@68525|delta/epsilon subdivisions,2WJ53@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	HTH_29,rve
CMS1_k127_968818_3	338963.Pcar_1382	2.347e-32	128.0	COG2963@1|root,COG2963@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_28,HTH_Tnp_1
CMS1_k127_968818_2	497964.CfE428DRAFT_2982	1.559e-60	218.0	COG1595@1|root,COG1595@2|Bacteria,46V3P@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
CMS1_k127_968818_1	886293.Sinac_7396	4.126e-104	369.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,2IXDF@203682|Planctomycetes	203682|Planctomycetes	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
CMS1_k127_97925_8	1202962.KB907161_gene375	1.089e-38	145.0	COG1805@1|root,COG1805@2|Bacteria,1QTUU@1224|Proteobacteria,1RMGH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrB	GO:0000166,GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008144,GO:0008150,GO:0008152,GO:0010181,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0019842,GO:0030001,GO:0030964,GO:0032553,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0044425,GO:0044464,GO:0048037,GO:0050136,GO:0050662,GO:0051179,GO:0051234,GO:0055114,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:1901265,GO:1901363,GO:1902444,GO:1902494	1.6.5.8	ko:K00347	-	-	-	-	ko00000,ko01000	-	-	-	NQR2_RnfD_RnfE
CMS1_k127_97925_6	1109445.AGSX01000184_gene2303	9.985e-75	259.0	COG2869@1|root,COG2869@2|Bacteria,1MVDI@1224|Proteobacteria,1RR85@1236|Gammaproteobacteria,1Z0CW@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrC	-	1.6.5.8	ko:K00348	-	-	-	-	ko00000,ko01000	-	-	-	FMN_bind
CMS1_k127_97925_2	1122194.AUHU01000002_gene2626	1.437e-89	300.0	COG1347@1|root,COG1347@2|Bacteria,1MUZR@1224|Proteobacteria,1RNFE@1236|Gammaproteobacteria,46413@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrD	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015672,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030001,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0051179,GO:0051234,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494	1.6.5.8	ko:K00349	-	-	-	-	ko00000,ko01000	-	-	-	Rnf-Nqr
CMS1_k127_97925_3	1121918.ARWE01000001_gene1330	6.099e-87	302.0	COG2209@1|root,COG2209@2|Bacteria,1R33S@1224|Proteobacteria	1224|Proteobacteria	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol	nqrE	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0051179,GO:0051234,GO:0055114,GO:0098796,GO:1902494	1.6.5.8	ko:K00350	-	-	-	-	ko00000,ko01000	-	-	-	Rnf-Nqr
CMS1_k127_97925_0	529507.PMI0357	3.299e-197	621.0	COG2871@1|root,COG2871@2|Bacteria,1QTUV@1224|Proteobacteria,1RPG5@1236|Gammaproteobacteria,3Z0VY@583|Proteus	1236|Gammaproteobacteria	C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway	nqrF	GO:0000166,GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0030964,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0044425,GO:0048037,GO:0050136,GO:0050660,GO:0050662,GO:0051179,GO:0051234,GO:0051536,GO:0051537,GO:0051540,GO:0055114,GO:0071949,GO:0097159,GO:0098796,GO:1901265,GO:1901363,GO:1902494	1.6.5.8	ko:K00351	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
CMS1_k127_97925_4	472759.Nhal_2554	7.204e-84	291.0	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,1RNMZ@1236|Gammaproteobacteria,1WWAK@135613|Chromatiales	135613|Chromatiales	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
CMS1_k127_97925_9	876044.IMCC3088_2817	2.072e-05	49.0	COG2991@1|root,COG2991@2|Bacteria,1Q5RE@1224|Proteobacteria,1RTZB@1236|Gammaproteobacteria,1J7D6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K05952	-	-	-	-	ko00000	-	-	-	NqrM
CMS1_k127_97925_7	649638.Trad_2493	2.822e-40	166.0	COG1215@1|root,COG1215@2|Bacteria,1WIG8@1297|Deinococcus-Thermus	2|Bacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
CMS1_k127_97925_5	1265505.ATUG01000002_gene2120	5.174e-78	289.0	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,42N78@68525|delta/epsilon subdivisions,2WM0M@28221|Deltaproteobacteria,2MHVS@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Mechanosensitive ion channel	mscS-2	-	-	-	-	-	-	-	-	-	-	-	MS_channel
CMS1_k127_97925_1	1121448.DGI_3104	2.474e-132	443.0	COG4907@1|root,COG4907@2|Bacteria,1MXPY@1224|Proteobacteria,42MA5@68525|delta/epsilon subdivisions,2WJGZ@28221|Deltaproteobacteria,2M9Y5@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Predicted membrane protein (DUF2207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2207
CMS1_k127_979980_0	378806.STAUR_2130	6.389e-78	274.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,1MWJA@1224|Proteobacteria,42P8D@68525|delta/epsilon subdivisions,2WMH1@28221|Deltaproteobacteria,2YY1Q@29|Myxococcales	28221|Deltaproteobacteria	KLT	Phosphotransferase enzyme family	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,Pkinase_Tyr,WD40
CMS1_k127_979980_2	497964.CfE428DRAFT_2982	2.598e-57	211.0	COG1595@1|root,COG1595@2|Bacteria,46V3P@74201|Verrucomicrobia	74201|Verrucomicrobia	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
CMS1_k127_979980_1	118168.MC7420_5234	1.308e-77	280.0	COG5563@1|root,COG5563@2|Bacteria,1GIA8@1117|Cyanobacteria,1HFHC@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
## 5065 queries scanned
## Total time (seconds): 113.94430780410767
## Rate: 44.45 q/s