## Tue Oct 15 12:39:51 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/Potential_rubisco_autotrophic/CMS1_bin.128.fa -m mmseqs --itype genome -o CMS1_bin.128 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/all_bins_1385/CMS1_bin.128 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
CMS1_k127_1000563_1	1128421.JAGA01000003_gene3678	5.588e-92	331.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2NQCZ@2323|unclassified Bacteria	2|Bacteria	K	NB-ARC domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_22,BTAD,NB-ARC,TPR_10,TPR_12,TPR_8,Trans_reg_C
CMS1_k127_1000563_2	479434.Sthe_2734	1.166e-61	218.0	COG5516@1|root,COG5516@2|Bacteria,2G7GV@200795|Chloroflexi	200795|Chloroflexi	S	Putative stress-induced transcription regulator	-	-	-	-	-	-	-	-	-	-	-	-	ABATE,zf-CGNR
CMS1_k127_1000563_0	886293.Sinac_7229	3.721e-243	769.0	arCOG10801@1|root,2Z9IC@2|Bacteria,2J23R@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1000563_3	889378.Spiaf_2411	5.99e-09	60.0	COG0667@1|root,COG0667@2|Bacteria,2JBDE@203691|Spirochaetes	203691|Spirochaetes	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS1_k127_1002161_5	886293.Sinac_2740	1.931e-99	337.0	COG3356@1|root,COG3356@2|Bacteria,2J4VF@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Neutral alkaline nonlysosomal ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
CMS1_k127_1002161_10	1123508.JH636442_gene4252	6.71e-21	104.0	COG4974@1|root,COG4974@2|Bacteria,2IY3V@203682|Planctomycetes	203682|Planctomycetes	D	tyrosine recombinase XerC	xerC	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
CMS1_k127_1002161_1	926550.CLDAP_27170	1.988e-140	459.0	COG4690@1|root,COG4690@2|Bacteria,2G7Y7@200795|Chloroflexi	200795|Chloroflexi	E	Peptidase family C69	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C69
CMS1_k127_1002161_2	234267.Acid_7161	1.856e-139	451.0	COG2159@1|root,COG2159@2|Bacteria,3Y5M2@57723|Acidobacteria	57723|Acidobacteria	E	PFAM Amidohydrolase 2	-	-	4.1.1.45	ko:K03392,ko:K07045	ko00380,ko01100,map00380,map01100	M00038	R04323	RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
CMS1_k127_1002161_0	926550.CLDAP_06650	3.142e-198	625.0	COG4664@1|root,COG4664@2|Bacteria,2G81X@200795|Chloroflexi	200795|Chloroflexi	Q	TRAP C4-dicarboxylate transport system permease DctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM
CMS1_k127_1002161_6	383372.Rcas_0364	8.589e-65	228.0	COG4665@1|root,COG4665@2|Bacteria,2G8FW@200795|Chloroflexi,377BR@32061|Chloroflexia	32061|Chloroflexia	Q	PFAM Tripartite ATP-independent periplasmic transporter, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
CMS1_k127_1002161_9	926550.CLDAP_15210	1.658e-24	110.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS1_k127_1002161_4	118163.Ple7327_4313	9.834e-106	353.0	COG0778@1|root,COG0778@2|Bacteria,1GD76@1117|Cyanobacteria	1117|Cyanobacteria	C	PFAM Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CMS1_k127_1002161_8	1056816.JAFQ01000004_gene4892	3.733e-40	162.0	COG0122@1|root,COG0122@2|Bacteria,2IEBZ@201174|Actinobacteria	201174|Actinobacteria	L	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1002161_7	321327.CYA_2243	7.509e-61	216.0	COG1881@1|root,COG1881@2|Bacteria,1G5SZ@1117|Cyanobacteria,1H1NJ@1129|Synechococcus	1117|Cyanobacteria	S	Phosphatidylethanolamine-binding protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
CMS1_k127_1002161_3	374847.Kcr_0279	2.363e-138	458.0	COG1793@1|root,arCOG01347@2157|Archaea	2157|Archaea	F	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair	lig	GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
CMS1_k127_1022290_3	33035.JPJF01000019_gene4239	1.644e-47	176.0	COG1063@1|root,COG1063@2|Bacteria,1VCXY@1239|Firmicutes,24U9W@186801|Clostridia	186801|Clostridia	E	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N
CMS1_k127_1022290_1	1205680.CAKO01000010_gene3712	7.459e-142	457.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,2TS02@28211|Alphaproteobacteria,2JR8C@204441|Rhodospirillales	204441|Rhodospirillales	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS1_k127_1022290_6	657309.BXY_34780	0.0003338	52.0	2A85D@1|root,30X65@2|Bacteria,4PAIP@976|Bacteroidetes,2FZR6@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1022290_5	1527444.ucyna2_00449	6.747e-19	98.0	COG1357@1|root,COG1357@2|Bacteria,1G4KR@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
CMS1_k127_1022290_0	1122915.AUGY01000004_gene5554	0.0	1159.0	COG2721@1|root,COG2721@2|Bacteria,1TPTX@1239|Firmicutes,4HAQZ@91061|Bacilli,26T2Q@186822|Paenibacillaceae	91061|Bacilli	G	Altronate hydrolase	uxaA	GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0006063,GO:0006082,GO:0008150,GO:0008152,GO:0008789,GO:0008867,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019577,GO:0019579,GO:0019580,GO:0019586,GO:0019698,GO:0019752,GO:0032787,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046365,GO:0046392,GO:0046395,GO:0046396,GO:0046397,GO:0071704,GO:0072329,GO:1901575	4.2.1.42,4.2.1.7	ko:K01685,ko:K01708	ko00040,ko00053,ko01100,map00040,map00053,map01100	M00631	R01540,R05608	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU02510	GD_AH_C,SAF
CMS1_k127_1022290_4	765420.OSCT_2714	3.276e-23	107.0	2ERP6@1|root,33J8I@2|Bacteria,2G9YM@200795|Chloroflexi,377B0@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1022290_2	1128421.JAGA01000001_gene2030	3.295e-70	243.0	COG1524@1|root,COG1524@2|Bacteria,2NQ0M@2323|unclassified Bacteria	2|Bacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
CMS1_k127_1022792_3	1348663.KCH_59570	4.942e-13	73.0	COG0673@1|root,COG0673@2|Bacteria,2IBFN@201174|Actinobacteria	201174|Actinobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_1022792_1	177437.HRM2_34090	3.684e-87	316.0	COG1262@1|root,COG4928@1|root,COG1262@2|Bacteria,COG4928@2|Bacteria,1Q99I@1224|Proteobacteria,4349K@68525|delta/epsilon subdivisions,2X1U0@28221|Deltaproteobacteria,2MPDU@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
CMS1_k127_1022792_0	1028800.RG540_PA11690	1.955e-125	416.0	COG4091@1|root,COG4091@2|Bacteria,1MUZX@1224|Proteobacteria,2TRZ0@28211|Alphaproteobacteria,4BBB0@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	homoserine dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	SAF
CMS1_k127_1022792_2	862517.HMPREF9225_1974	3.079e-27	121.0	COG0388@1|root,COG0388@2|Bacteria,1TQDK@1239|Firmicutes,24AWV@186801|Clostridia	186801|Clostridia	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
CMS1_k127_1024180_3	1382306.JNIM01000001_gene471	2.923e-81	278.0	COG2141@1|root,COG2141@2|Bacteria,2G5QC@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS1_k127_1024180_4	1032480.MLP_35480	1.767e-38	158.0	COG3173@1|root,COG3173@2|Bacteria,2IA48@201174|Actinobacteria,4DR9I@85009|Propionibacteriales	201174|Actinobacteria	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS1_k127_1024180_6	1055815.AYYA01000069_gene1724	3.675e-09	61.0	COG1359@1|root,COG1359@2|Bacteria,1NGPW@1224|Proteobacteria,1T0ME@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
CMS1_k127_1024180_0	1128421.JAGA01000003_gene3678	1.061e-131	460.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2NQCZ@2323|unclassified Bacteria	2|Bacteria	K	NB-ARC domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_22,BTAD,NB-ARC,TPR_10,TPR_12,TPR_8,Trans_reg_C
CMS1_k127_1024180_1	489825.LYNGBM3L_24440	3.099e-126	411.0	COG0604@1|root,COG0604@2|Bacteria,1G3SY@1117|Cyanobacteria,1HEBR@1150|Oscillatoriales	1117|Cyanobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
CMS1_k127_1024180_5	931276.Cspa_c22430	4.451e-13	78.0	COG0703@1|root,COG0703@2|Bacteria,1UMGK@1239|Firmicutes,24MFB@186801|Clostridia,36KKR@31979|Clostridiaceae	186801|Clostridia	E	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1024180_2	1123242.JH636434_gene4980	6.125e-103	340.0	COG0262@1|root,COG0262@2|Bacteria,2IYX1@203682|Planctomycetes	203682|Planctomycetes	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
CMS1_k127_1025781_1	331678.Cphamn1_1691	2.232e-26	110.0	COG3743@1|root,COG3743@2|Bacteria,1FF2H@1090|Chlorobi	1090|Chlorobi	S	Domain of unknown function (DUF4332)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4332
CMS1_k127_1025781_0	292459.STH886	6.43e-273	876.0	COG1201@1|root,COG1201@2|Bacteria,1UHYQ@1239|Firmicutes,25E79@186801|Clostridia	186801|Clostridia	L	DEAD DEAH box helicase	-	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
CMS1_k127_103888_9	1120949.KB903329_gene9217	8.049e-35	141.0	COG2909@1|root,COG2909@2|Bacteria,2IDM6@201174|Actinobacteria,4DCIQ@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,GerE,Pkinase
CMS1_k127_103888_8	485913.Krac_8724	9.045e-37	144.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
CMS1_k127_103888_13	329726.AM1_5033	3.44e-05	48.0	COG3324@1|root,COG3324@2|Bacteria,1GA6T@1117|Cyanobacteria	1117|Cyanobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	-
CMS1_k127_103888_2	926550.CLDAP_14490	6.815e-85	286.0	COG0406@1|root,COG0406@2|Bacteria,2G72Q@200795|Chloroflexi	200795|Chloroflexi	G	Phosphoglycerate mutase family	-	-	5.4.2.12	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
CMS1_k127_103888_6	671143.DAMO_1988	4.299e-54	204.0	COG1262@1|root,COG1262@2|Bacteria,2NR8C@2323|unclassified Bacteria	2|Bacteria	S	Sulfatase-modifying factor enzyme 1	-	-	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	FGE-sulfatase
CMS1_k127_103888_5	1123501.KB902285_gene2161	3.407e-54	201.0	COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,2TUUJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	1.1.1.60	ko:K00042	ko00630,ko01100,map00630,map01100	-	R01745,R01747	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
CMS1_k127_103888_0	1205680.CAKO01000035_gene262	1.326e-203	646.0	COG0526@1|root,COG0526@2|Bacteria,1RC8N@1224|Proteobacteria,2U7IW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS1_k127_103888_10	1323663.AROI01000026_gene1884	8.624e-29	121.0	2E6FA@1|root,3312Q@2|Bacteria,1NCPQ@1224|Proteobacteria,1SRUF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_103888_11	1211815.CBYP010000063_gene1890	9.646e-20	90.0	2DS3D@1|root,33EC4@2|Bacteria,2GXNR@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_103888_4	1313301.AUGC01000007_gene578	9.37e-55	207.0	COG0458@1|root,COG0458@2|Bacteria	2|Bacteria	F	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4
CMS1_k127_103888_7	1232437.KL662015_gene1264	3.681e-53	190.0	2C56A@1|root,32EMF@2|Bacteria,1NV56@1224|Proteobacteria,42ZEW@68525|delta/epsilon subdivisions,2WV0I@28221|Deltaproteobacteria,2MNCA@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_103888_1	1120950.KB892750_gene6826	1.587e-144	464.0	COG1649@1|root,COG1649@2|Bacteria	2|Bacteria	F	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	GHL10,Polysacc_deac_1
CMS1_k127_103888_3	357808.RoseRS_1569	8.451e-72	257.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Trypsin,Trypsin_2
CMS1_k127_1042080_2	309799.DICTH_1598	3.219e-62	226.0	COG1173@1|root,COG1173@2|Bacteria	2|Bacteria	P	ABC-type dipeptide oligopeptide nickel transport systems, permease components	oppC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
CMS1_k127_1042080_1	706587.Desti_5628	2.158e-122	402.0	COG0601@1|root,COG0601@2|Bacteria,1NS80@1224|Proteobacteria,42N5D@68525|delta/epsilon subdivisions,2WIRR@28221|Deltaproteobacteria,2MQBC@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_1042080_0	1380394.JADL01000001_gene2217	7.41e-138	462.0	COG0747@1|root,COG0747@2|Bacteria,1MU3P@1224|Proteobacteria,2TT4M@28211|Alphaproteobacteria,2JQRE@204441|Rhodospirillales	204441|Rhodospirillales	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_1044327_11	765420.OSCT_2174	3.213e-25	106.0	COG0455@1|root,COG0455@2|Bacteria,2G9ZU@200795|Chloroflexi,3772G@32061|Chloroflexia	32061|Chloroflexia	D	NUBPL iron-transfer P-loop NTPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
CMS1_k127_1044327_3	671143.DAMO_1946	1.65e-125	433.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	PKD,SBBP
CMS1_k127_1044327_14	1185876.BN8_04387	6.697e-17	96.0	COG3934@1|root,COG3934@2|Bacteria,4NHVX@976|Bacteroidetes	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase,Glyco_hydro_2_C
CMS1_k127_1044327_17	935567.JAES01000008_gene1990	1.884e-09	71.0	COG1652@1|root,COG1652@2|Bacteria,1N3P8@1224|Proteobacteria,1SY85@1236|Gammaproteobacteria,1X82C@135614|Xanthomonadales	135614|Xanthomonadales	S	peptidoglycan-binding protein, lysm	-	-	-	-	-	-	-	-	-	-	-	-	LysM
CMS1_k127_1044327_8	316274.Haur_4061	1.423e-63	244.0	COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,2G8PA@200795|Chloroflexi,376UG@32061|Chloroflexia	32061|Chloroflexia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
CMS1_k127_1044327_0	926550.CLDAP_00030	8.557e-174	558.0	COG1418@1|root,COG4372@1|root,COG1418@2|Bacteria,COG4372@2|Bacteria,2G620@200795|Chloroflexi	200795|Chloroflexi	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
CMS1_k127_1044327_9	926550.CLDAP_16260	6.512e-51	189.0	COG2137@1|root,COG2137@2|Bacteria,2G6WA@200795|Chloroflexi	200795|Chloroflexi	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
CMS1_k127_1044327_1	926550.CLDAP_24880	6.186e-161	512.0	COG0468@1|root,COG0468@2|Bacteria,2G5WE@200795|Chloroflexi	200795|Chloroflexi	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
CMS1_k127_1044327_16	314260.PB2503_08744	1.582e-11	67.0	COG1722@1|root,COG1722@2|Bacteria,1PTYQ@1224|Proteobacteria,2UFD6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
CMS1_k127_1044327_4	926569.ANT_26230	5.641e-112	374.0	COG1570@1|root,COG1570@2|Bacteria,2G5M3@200795|Chloroflexi	200795|Chloroflexi	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
CMS1_k127_1044327_13	321332.CYB_0562	7.753e-24	117.0	COG2385@1|root,COG2385@2|Bacteria,1G0XG@1117|Cyanobacteria,1H0F9@1129|Synechococcus	1117|Cyanobacteria	D	COG2385 Sporulation protein and related proteins	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
CMS1_k127_1044327_5	383372.Rcas_0363	8.673e-87	296.0	COG0679@1|root,COG0679@2|Bacteria,2G7V4@200795|Chloroflexi,376PB@32061|Chloroflexia	32061|Chloroflexia	S	PFAM Auxin Efflux Carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
CMS1_k127_1044327_12	1521187.JPIM01000042_gene1850	3.43e-24	106.0	2FFVE@1|root,347SF@2|Bacteria,2GB3K@200795|Chloroflexi,377UV@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1044327_6	1408254.T458_19885	8.209e-76	263.0	COG1402@1|root,COG1402@2|Bacteria,1V0N8@1239|Firmicutes,4HK2P@91061|Bacilli,276QJ@186822|Paenibacillaceae	91061|Bacilli	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
CMS1_k127_1044327_10	697282.Mettu_3553	7.599e-41	162.0	COG0560@1|root,COG0560@2|Bacteria,1PIND@1224|Proteobacteria,1S9GK@1236|Gammaproteobacteria,1XEK5@135618|Methylococcales	135618|Methylococcales	E	haloacid dehalogenase-like hydrolase	-	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	HAD
CMS1_k127_1044327_7	1125971.ASJB01000017_gene6090	1.057e-71	259.0	COG0116@1|root,COG0116@2|Bacteria,2I2N1@201174|Actinobacteria,4DZAK@85010|Pseudonocardiales	201174|Actinobacteria	L	SAM-dependent	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1044327_2	349161.Dred_0014	1.218e-154	504.0	COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,248H9@186801|Clostridia,260G0@186807|Peptococcaceae	186801|Clostridia	E	D-isomer specific 2-hydroxyacid dehydrogenase catalytic	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
CMS1_k127_1044661_4	593117.TGAM_0970	1.588e-08	63.0	COG0419@1|root,COG2247@1|root,COG2319@1|root,COG5306@1|root,arCOG02559@1|root,arCOG03264@1|root,arCOG00368@2157|Archaea,arCOG00388@2157|Archaea,arCOG02491@2157|Archaea,arCOG02559@2157|Archaea,arCOG03264@2157|Archaea,arCOG03512@2157|Archaea,2XYKK@28890|Euryarchaeota,24394@183968|Thermococci	183968|Thermococci	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,PEGA
CMS1_k127_1044661_1	926550.CLDAP_36310	8.677e-83	305.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PA14,PD40,PKD,VPEP
CMS1_k127_1044661_0	926550.CLDAP_36300	4.592e-101	349.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,2G5WM@200795|Chloroflexi	200795|Chloroflexi	DM	PFAM lipopolysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1044661_3	865937.Gilli_1955	8.518e-13	79.0	COG0463@1|root,COG0500@1|root,COG0463@2|Bacteria,COG2226@2|Bacteria,4NR1C@976|Bacteroidetes,1IJXZ@117743|Flavobacteriia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS1_k127_1044661_2	1313421.JHBV01000029_gene1869	7.003e-44	168.0	COG0726@1|root,COG0726@2|Bacteria,4NPJX@976|Bacteroidetes	976|Bacteroidetes	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
CMS1_k127_1050226_3	311424.DhcVS_1083	1.821e-21	99.0	COG0589@1|root,COG0589@2|Bacteria,2G91P@200795|Chloroflexi,34DF4@301297|Dehalococcoidia	301297|Dehalococcoidia	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS1_k127_1050226_0	266117.Rxyl_1929	9.649e-298	933.0	COG1067@1|root,COG1067@2|Bacteria,2H2TE@201174|Actinobacteria	201174|Actinobacteria	O	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_32,Lon_C
CMS1_k127_1050226_2	926550.CLDAP_15210	1.003e-40	157.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS1_k127_1050226_4	509191.AEDB02000028_gene2901	0.0002839	44.0	2EFGV@1|root,3399G@2|Bacteria,1U5Y2@1239|Firmicutes,24WP5@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1050226_1	926569.ANT_29200	2.101e-146	487.0	COG4412@1|root,COG4412@2|Bacteria,2G622@200795|Chloroflexi	200795|Chloroflexi	S	Immune inhibitor A peptidase M6	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M6
CMS1_k127_1051749_4	383372.Rcas_0166	7.799e-46	171.0	COG1187@1|root,COG1187@2|Bacteria,2G6HU@200795|Chloroflexi,375DQ@32061|Chloroflexia	32061|Chloroflexia	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
CMS1_k127_1051749_0	926550.CLDAP_16120	1.729e-182	592.0	COG2866@1|root,COG2866@2|Bacteria,2G7U3@200795|Chloroflexi	200795|Chloroflexi	E	Zn_pept	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
CMS1_k127_1051749_3	926569.ANT_11700	6.424e-50	184.0	COG1386@1|root,COG1386@2|Bacteria,2G6V6@200795|Chloroflexi	200795|Chloroflexi	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
CMS1_k127_1051749_5	1117647.M5M_19125	1.285e-27	125.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,1RMCY@1236|Gammaproteobacteria,1J4F8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019904,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
CMS1_k127_1051749_6	1123308.KB904542_gene1756	2.034e-25	117.0	COG0561@1|root,COG0561@2|Bacteria,1VAFW@1239|Firmicutes,4HIFQ@91061|Bacilli	91061|Bacilli	S	Sucrose-6F-phosphate phosphohydrolase	XK27_04800	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
CMS1_k127_1051749_2	118166.JH976537_gene1571	3.478e-120	406.0	COG4715@1|root,COG4715@2|Bacteria,1G37G@1117|Cyanobacteria,1HAEP@1150|Oscillatoriales	1117|Cyanobacteria	S	Zinc finger, SWIM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SWIM
CMS1_k127_1051749_1	880073.Calab_1650	1.619e-120	395.0	COG0492@1|root,COG0492@2|Bacteria,2NNS7@2323|unclassified Bacteria	2|Bacteria	O	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748	1.8.1.9	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000,ko03110	-	-	iNJ661.Rv3913	Pyr_redox_2,Thioredoxin
CMS1_k127_1061781_16	525904.Tter_2344	1.272e-47	175.0	COG1472@1|root,COG1472@2|Bacteria,2NQT7@2323|unclassified Bacteria	2|Bacteria	G	Glycosyl hydrolase family 3 C-terminal domain	bgxA	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Glyco_hydro_3,Glyco_hydro_3_C
CMS1_k127_1061781_15	1297570.MESS4_160063	7.934e-53	190.0	COG2510@1|root,COG2510@2|Bacteria,1RJ4E@1224|Proteobacteria,2U7CK@28211|Alphaproteobacteria,43K38@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	EamA-like transporter family	-	-	-	ko:K08978	-	-	-	-	ko00000,ko02000	2.A.7.2	-	-	EamA
CMS1_k127_1061781_17	485913.Krac_7163	1.966e-42	172.0	COG0477@1|root,COG2814@2|Bacteria,2G6D7@200795|Chloroflexi	2|Bacteria	EGP	Major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
CMS1_k127_1061781_24	374847.Kcr_0315	8.441e-22	109.0	COG0477@1|root,arCOG00130@2157|Archaea	2157|Archaea	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3,Sugar_tr
CMS1_k127_1061781_13	1123278.KB893607_gene4617	2.059e-74	259.0	COG3394@1|root,COG3394@2|Bacteria,4PNAT@976|Bacteroidetes,47TGM@768503|Cytophagia	976|Bacteroidetes	G	YdjC-like protein	-	-	3.5.1.105	ko:K03478	-	-	-	-	ko00000,ko01000	-	-	-	YdjC
CMS1_k127_1061781_12	525904.Tter_2348	1.283e-87	299.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	nicD	GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0044237,GO:0044248	3.5.1.106	ko:K15357,ko:K19311	ko00760,ko01120,map00760,map01120	M00622	R09126	RC00323,RC02431	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS1_k127_1061781_8	349521.HCH_01563	6.968e-110	363.0	COG0657@1|root,COG0657@2|Bacteria,1R4AU@1224|Proteobacteria,1RQMN@1236|Gammaproteobacteria,1XR8Q@135619|Oceanospirillales	135619|Oceanospirillales	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
CMS1_k127_1061781_2	525904.Tter_1978	1.512e-132	427.0	COG1402@1|root,COG1402@2|Bacteria,2NRPM@2323|unclassified Bacteria	2|Bacteria	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
CMS1_k127_1061781_22	58344.JOEL01000003_gene1433	1.743e-23	102.0	2E8T5@1|root,3333Y@2|Bacteria,2IS1D@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1061781_9	331869.BAL199_27206	2.725e-109	358.0	COG0412@1|root,COG0412@2|Bacteria,1R9JT@1224|Proteobacteria,2U4J1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	BAAT / Acyl-CoA thioester hydrolase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	DLH
CMS1_k127_1061781_25	1396418.BATQ01000151_gene2335	2.055e-15	78.0	COG0657@1|root,COG0657@2|Bacteria,46TVH@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,EF-hand_5
CMS1_k127_1061781_7	309803.CTN_0638	1e-113	393.0	COG0747@1|root,COG0747@2|Bacteria,2GCNZ@200918|Thermotogae	200918|Thermotogae	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_1061781_4	390874.Tpet_1686	1.191e-124	411.0	COG4608@1|root,COG4608@2|Bacteria,2GC6X@200918|Thermotogae	200918|Thermotogae	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
CMS1_k127_1061781_3	1304880.JAGB01000002_gene2307	6.172e-126	411.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia	186801|Clostridia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
CMS1_k127_1061781_1	390874.Tpet_1684	1.639e-144	467.0	COG1173@1|root,COG1173@2|Bacteria,2GCBY@200918|Thermotogae	200918|Thermotogae	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
CMS1_k127_1061781_5	706587.Desti_5628	7.23e-117	384.0	COG0601@1|root,COG0601@2|Bacteria,1NS80@1224|Proteobacteria,42N5D@68525|delta/epsilon subdivisions,2WIRR@28221|Deltaproteobacteria,2MQBC@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_1061781_6	344747.PM8797T_16018	5.329e-116	382.0	COG1621@1|root,COG1621@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 32 family	-	-	3.2.1.26,3.2.1.65	ko:K01193,ko:K01212	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R00802,R02410,R03635,R03921,R05624,R06088,R11311	RC00028,RC00077,RC03278	ko00000,ko00001,ko01000	-	GH32	-	Glyco_hydro_32N,Glyco_hydro_43
CMS1_k127_1061781_23	1131269.AQVV01000004_gene596	1.614e-22	110.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_1061781_21	383372.Rcas_2255	1.07e-28	128.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_1061781_14	1131269.AQVV01000004_gene596	2.991e-56	210.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_1061781_19	1501230.ET33_24130	3.151e-32	143.0	COG0454@1|root,COG0456@2|Bacteria,1V5BE@1239|Firmicutes,4HHNK@91061|Bacilli,26XNW@186822|Paenibacillaceae	91061|Bacilli	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS1_k127_1061781_18	313628.LNTAR_01337	5.005e-36	155.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_1061781_0	926550.CLDAP_11690	3.891e-210	681.0	COG0517@1|root,COG0617@1|root,COG0618@1|root,COG0517@2|Bacteria,COG0617@2|Bacteria,COG0618@2|Bacteria,2G8YQ@200795|Chloroflexi	200795|Chloroflexi	H	Polynucleotide adenylyltransferase region	-	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	CBS,DHH,DHHA1,PolyA_pol,PolyA_pol_RNAbd
CMS1_k127_1061781_10	696281.Desru_0408	8.005e-107	354.0	COG1575@1|root,COG1575@2|Bacteria,1TSZV@1239|Firmicutes,24DJF@186801|Clostridia,26573@186807|Peptococcaceae	186801|Clostridia	H	Belongs to the MenA family. Type 1 subfamily	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
CMS1_k127_1061781_11	926550.CLDAP_31960	1.517e-96	332.0	COG1357@1|root,COG1357@2|Bacteria,2G8U9@200795|Chloroflexi	200795|Chloroflexi	S	PFAM pentapeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
CMS1_k127_1061781_20	1396141.BATP01000034_gene4229	1.398e-29	123.0	COG1940@1|root,COG1940@2|Bacteria	2|Bacteria	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PMI_typeI,ROK
CMS1_k127_1063380_9	1132509.C447_13257	5.476e-124	414.0	COG3119@1|root,arCOG02785@2157|Archaea	2157|Archaea	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
CMS1_k127_1063380_24	311424.DhcVS_1083	6.133e-20	96.0	COG0589@1|root,COG0589@2|Bacteria,2G91P@200795|Chloroflexi,34DF4@301297|Dehalococcoidia	301297|Dehalococcoidia	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS1_k127_1063380_22	1207063.P24_07241	1.876e-34	134.0	2CIU6@1|root,32S8H@2|Bacteria,1MZTN@1224|Proteobacteria,2UCA8@28211|Alphaproteobacteria,2JUA3@204441|Rhodospirillales	204441|Rhodospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1063380_2	266265.Bxe_B1939	2.353e-177	565.0	COG3185@1|root,COG3185@2|Bacteria,1MVR0@1224|Proteobacteria,2VJHM@28216|Betaproteobacteria,1JZQQ@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Acyclic terpene utilisation family protein AtuA	-	-	-	-	-	-	-	-	-	-	-	-	AtuA
CMS1_k127_1063380_10	357808.RoseRS_1608	1.103e-111	368.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	-	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
CMS1_k127_1063380_5	1304880.JAGB01000003_gene1239	2.096e-139	447.0	COG1957@1|root,COG1957@2|Bacteria,1TSSS@1239|Firmicutes,24A4D@186801|Clostridia	186801|Clostridia	F	Psort location Cytoplasmic, score	-	-	3.2.2.1	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
CMS1_k127_1063380_8	1303518.CCALI_02204	2.629e-128	415.0	COG5285@1|root,COG5285@2|Bacteria	2|Bacteria	Q	dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
CMS1_k127_1063380_14	661478.OP10G_2949	1.643e-92	311.0	COG5285@1|root,COG5285@2|Bacteria	2|Bacteria	Q	dioxygenase activity	-	-	1.14.11.18	ko:K00477,ko:K18562	ko00332,ko01130,ko04146,map00332,map01130,map04146	-	R10415,R10735	RC01525,RC03174	ko00000,ko00001,ko01000	-	-	-	PhyH
CMS1_k127_1063380_19	448385.sce0538	5.532e-47	196.0	COG0457@1|root,COG0515@1|root,COG3899@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG3899@2|Bacteria,1PFZX@1224|Proteobacteria,43F1T@68525|delta/epsilon subdivisions,2X316@28221|Deltaproteobacteria,2YTXV@29|Myxococcales	28221|Deltaproteobacteria	KLT	AAA ATPase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,Pkinase
CMS1_k127_1063380_17	1198452.Jab_2c08630	3.034e-61	243.0	COG1235@1|root,COG1235@2|Bacteria,1NW4Z@1224|Proteobacteria,2VNBH@28216|Betaproteobacteria,476U3@75682|Oxalobacteraceae	1224|Proteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
CMS1_k127_1063380_12	1128421.JAGA01000001_gene2226	7.927e-101	339.0	COG0673@1|root,COG0673@2|Bacteria,2NQDT@2323|unclassified Bacteria	2|Bacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_1063380_15	1499967.BAYZ01000019_gene6333	1.079e-74	262.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS1_k127_1063380_1	1463821.JOGR01000003_gene1001	2.994e-198	646.0	COG3250@1|root,COG3250@2|Bacteria,2I3EF@201174|Actinobacteria	201174|Actinobacteria	G	alpha-L-rhamnosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_106
CMS1_k127_1063380_11	485913.Krac_4939	3.822e-103	342.0	COG2120@1|root,COG2120@2|Bacteria,2G9IP@200795|Chloroflexi	200795|Chloroflexi	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
CMS1_k127_1063380_4	479434.Sthe_3070	2.946e-154	498.0	COG0436@1|root,COG0436@2|Bacteria	2|Bacteria	E	Aminotransferase	-	-	2.6.1.1	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS1_k127_1063380_18	526227.Mesil_2431	3.821e-53	192.0	2F64E@1|root,33YNP@2|Bacteria	2|Bacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,MDMPI_N
CMS1_k127_1063380_3	1385935.N836_32270	3.712e-156	500.0	COG2230@1|root,COG2230@2|Bacteria,1G3TN@1117|Cyanobacteria,1H8KG@1150|Oscillatoriales	1117|Cyanobacteria	M	Methylase involved in ubiquinone menaquinone biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
CMS1_k127_1063380_6	485913.Krac_5027	7.799e-136	466.0	COG2909@1|root,COG3903@1|root,COG2909@2|Bacteria,COG3903@2|Bacteria,2G7SC@200795|Chloroflexi	200795|Chloroflexi	K	intracellular signal transduction	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12
CMS1_k127_1063380_23	471853.Bcav_0070	2.684e-28	116.0	2E3U2@1|root,32YRF@2|Bacteria,2GSNJ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1063380_0	869210.Marky_1372	2.094e-208	667.0	COG0557@1|root,COG0557@2|Bacteria,1WIKR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	ribonuclease II	-	-	3.1.13.1	ko:K01147	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNB
CMS1_k127_1063380_20	1123508.JH636449_gene7334	4.061e-44	172.0	COG0329@1|root,COG0329@2|Bacteria,2J1TV@203682|Planctomycetes	203682|Planctomycetes	EM	Dihydrodipicolinate synthetase family	-	-	-	-	-	-	-	-	-	-	-	-	DHDPS
CMS1_k127_1063380_7	1196322.A370_05866	1.29e-129	432.0	COG0457@1|root,COG0457@2|Bacteria,1UJ9T@1239|Firmicutes,24CZA@186801|Clostridia,36G3G@31979|Clostridiaceae	186801|Clostridia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2
CMS1_k127_1063380_16	1123073.KB899241_gene3441	7.372e-68	239.0	COG1028@1|root,COG1028@2|Bacteria	1123073.KB899241_gene3441|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1063380_13	476272.RUMHYD_03502	4.043e-99	335.0	COG4948@1|root,COG4948@2|Bacteria,1TS0S@1239|Firmicutes,24AE7@186801|Clostridia,3Y0NS@572511|Blautia	186801|Clostridia	M	Mandelate racemase / muconate lactonizing enzyme, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
CMS1_k127_1063380_21	1445613.JALM01000067_gene5557	3.468e-41	163.0	COG3458@1|root,COG3458@2|Bacteria	2|Bacteria	Q	cephalosporin-C deacetylase activity	-	-	3.1.1.41	ko:K01060	ko00311,ko01130,map00311,map01130	-	R03062	RC00020,RC00041	ko00000,ko00001,ko01000	-	-	-	AXE1
CMS1_k127_1070412_2	765420.OSCT_2991	9.833e-15	81.0	COG2010@1|root,COG3258@1|root,COG2010@2|Bacteria,COG3258@2|Bacteria	2|Bacteria	C	Cytochrome c	qcrC	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005507,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006464,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016021,GO:0016491,GO:0016667,GO:0016669,GO:0016740,GO:0016782,GO:0016783,GO:0018192,GO:0018193,GO:0018198,GO:0018307,GO:0019417,GO:0019538,GO:0020037,GO:0022900,GO:0031224,GO:0031226,GO:0036211,GO:0040007,GO:0042597,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046906,GO:0046914,GO:0046982,GO:0046983,GO:0048037,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:0098822,GO:1901363,GO:1901564	1.8.2.2	ko:K00406,ko:K03889,ko:K17222,ko:K19713	ko00190,ko00920,ko01100,ko01120,ko02020,map00190,map00920,map01100,map01120,map02020	M00151,M00156,M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cytochrome_CBB3
CMS1_k127_1070412_1	547163.BN979_04869	8.467e-28	118.0	COG0607@1|root,COG0607@2|Bacteria,2IIT0@201174|Actinobacteria,239PK@1762|Mycobacteriaceae	201174|Actinobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CMS1_k127_1070412_0	696369.KI912183_gene1776	3.137e-56	204.0	COG0500@1|root,COG2226@2|Bacteria,1V0C5@1239|Firmicutes,24IDC@186801|Clostridia,261M8@186807|Peptococcaceae	186801|Clostridia	Q	PFAM methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS1_k127_107760_2	926569.ANT_09610	1.066e-36	154.0	COG1668@1|root,COG1668@2|Bacteria,2G8PJ@200795|Chloroflexi	200795|Chloroflexi	CP	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
CMS1_k127_107760_3	1399115.U719_13695	4.269e-14	85.0	COG1668@1|root,COG1668@2|Bacteria,1TXRK@1239|Firmicutes,4HC9K@91061|Bacilli,3WE95@539002|Bacillales incertae sedis	91061|Bacilli	CP	ABC-2 family transporter protein	yhaP	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
CMS1_k127_107760_0	357808.RoseRS_1419	2.179e-204	645.0	COG0624@1|root,COG0624@2|Bacteria,2G62C@200795|Chloroflexi,3771C@32061|Chloroflexia	32061|Chloroflexia	E	peptidase dimerisation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
CMS1_k127_107760_1	926560.KE387027_gene1021	4.629e-73	250.0	2DB7V@1|root,2Z7NX@2|Bacteria,1WM7S@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1081104_0	63737.Npun_F5335	2.653e-166	535.0	COG3875@1|root,COG3875@2|Bacteria,1G82E@1117|Cyanobacteria	1117|Cyanobacteria	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
CMS1_k127_1081104_3	595460.RRSWK_04508	5.604e-62	220.0	COG1878@1|root,COG1878@2|Bacteria,2IZXG@203682|Planctomycetes	203682|Planctomycetes	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
CMS1_k127_1081104_7	926550.CLDAP_07830	4.925e-29	132.0	COG4447@1|root,COG4447@2|Bacteria,2G66V@200795|Chloroflexi	200795|Chloroflexi	G	glycosyl hydrolase, BNR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CMS1_k127_1081104_5	926550.CLDAP_11480	6.947e-49	186.0	COG2968@1|root,COG2968@2|Bacteria,2G6UC@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF541)	-	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
CMS1_k127_1081104_1	926550.CLDAP_08440	6.9e-82	278.0	COG2197@1|root,COG2197@2|Bacteria,2G6T1@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS1_k127_1081104_4	292459.STH493	4.249e-50	203.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,1TQI3@1239|Firmicutes,249R9@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
CMS1_k127_1081104_8	1003200.AXXA_24900	1.556e-14	88.0	COG2199@1|root,COG3706@2|Bacteria,1MX83@1224|Proteobacteria,2VP2I@28216|Betaproteobacteria,3T1SE@506|Alcaligenaceae	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_1
CMS1_k127_1081104_6	1380391.JIAS01000012_gene3961	6.201e-44	177.0	COG1653@1|root,COG1653@2|Bacteria,1PHMZ@1224|Proteobacteria,2V8PA@28211|Alphaproteobacteria,2JXKB@204441|Rhodospirillales	204441|Rhodospirillales	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1
CMS1_k127_1081104_2	926550.CLDAP_39410	1.526e-62	221.0	COG1105@1|root,COG1105@2|Bacteria,2G7B1@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the carbohydrate kinase PfkB family	-	-	2.7.1.56	ko:K00882	ko00051,map00051	-	R02071	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
CMS1_k127_1081229_1	1128421.JAGA01000003_gene3678	3.66e-62	246.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2NQCZ@2323|unclassified Bacteria	2|Bacteria	K	NB-ARC domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_22,BTAD,NB-ARC,TPR_10,TPR_12,TPR_8,Trans_reg_C
CMS1_k127_1081229_0	1057002.KB905370_gene1565	1.781e-94	352.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2TQVN@28211|Alphaproteobacteria,4B81Q@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylate	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,DZR,Guanylate_cyc,TPR_12
CMS1_k127_1081792_1	880073.Calab_1738	1.165e-137	455.0	COG0018@1|root,COG0018@2|Bacteria,2NNSE@2323|unclassified Bacteria	2|Bacteria	J	Arginyl tRNA synthetase N terminal dom	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iAF987.Gmet_1434	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
CMS1_k127_1081792_2	1382356.JQMP01000001_gene959	1.231e-128	420.0	COG4608@1|root,COG4608@2|Bacteria,2GARG@200795|Chloroflexi,27Z3W@189775|Thermomicrobia	189775|Thermomicrobia	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
CMS1_k127_1081792_3	1382356.JQMP01000001_gene960	8.369e-120	393.0	COG0444@1|root,COG0444@2|Bacteria,2GBE3@200795|Chloroflexi,27Z2B@189775|Thermomicrobia	189775|Thermomicrobia	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
CMS1_k127_1081792_6	926550.CLDAP_31910	2.202e-73	258.0	COG1173@1|root,COG1173@2|Bacteria	2|Bacteria	P	ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
CMS1_k127_1081792_4	926550.CLDAP_31900	9.075e-102	342.0	COG0601@1|root,COG0601@2|Bacteria,2G6RM@200795|Chloroflexi	200795|Chloroflexi	P	COGs COG0601 ABC-type dipeptide oligopeptide nickel transport systems permease components	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_1081792_0	926550.CLDAP_31890	7.682e-141	468.0	COG0747@1|root,COG0747@2|Bacteria,2G89C@200795|Chloroflexi	200795|Chloroflexi	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_1081792_5	357808.RoseRS_4272	5.23e-83	306.0	COG2931@1|root,COG3210@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,2G88I@200795|Chloroflexi,3780V@32061|Chloroflexia	32061|Chloroflexia	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1083380_0	1173025.GEI7407_1785	2.521e-305	961.0	COG1122@1|root,COG2319@1|root,COG1122@2|Bacteria,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1H7FN@1150|Oscillatoriales	1117|Cyanobacteria	KLT	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,WD40
CMS1_k127_1083380_3	665956.HMPREF1032_00160	4.967e-178	568.0	COG0673@1|root,COG0673@2|Bacteria,1TRCC@1239|Firmicutes,248FQ@186801|Clostridia	186801|Clostridia	S	Oxidoreductase NAD-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_1083380_16	1499967.BAYZ01000190_gene3812	3.83e-20	99.0	COG3743@1|root,COG3743@2|Bacteria	2|Bacteria	S	rRNA binding	rplU	-	-	ko:K02879,ko:K02888,ko:K02890,ko:K02899,ko:K02967,ko:K04074	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03036	-	-	-	HHH_5,Ribosomal_L21p
CMS1_k127_1083380_10	344747.PM8797T_00492	4.436e-76	267.0	COG0667@1|root,COG0667@2|Bacteria,2IXRI@203682|Planctomycetes	203682|Planctomycetes	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS1_k127_1083380_18	4641.GSMUA_Achr9P31030_001	2.192e-05	52.0	COG2453@1|root,KOG1716@2759|Eukaryota,37R4E@33090|Viridiplantae,3GHHZ@35493|Streptophyta,3KN0D@4447|Liliopsida	35493|Streptophyta	V	Actin-fragmin kinase, catalytic	-	-	3.1.3.16,3.1.3.48	ko:K14165	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	Act-Frag_cataly,DSPc
CMS1_k127_1083380_9	273526.SMDB11_4230	1.009e-79	274.0	COG0451@1|root,COG0451@2|Bacteria,1MWVE@1224|Proteobacteria,1S45Y@1236|Gammaproteobacteria,400ZV@613|Serratia	1236|Gammaproteobacteria	GM	epimerase	-	-	1.1.1.203	ko:K18981	ko00053,map00053	-	R10841	RC00066	ko00000,ko00001,ko01000	-	-	-	Epimerase
CMS1_k127_1083380_2	383372.Rcas_2449	4.363e-218	684.0	COG1486@1|root,COG1486@2|Bacteria	2|Bacteria	G	melibiose metabolic process	-	-	3.2.1.22,3.2.1.86	ko:K01222,ko:K07406	ko00010,ko00052,ko00500,ko00561,ko00600,ko00603,map00010,map00052,map00500,map00561,map00600,map00603	-	R00839,R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05133,R05134,R05549,R05961,R06091	RC00049,RC00059,RC00171,RC00451,RC00714	ko00000,ko00001,ko01000	-	GT4	iLJ478.TM1068	Glyco_hydro_4,Glyco_hydro_4C
CMS1_k127_1083380_4	158189.SpiBuddy_0350	4.553e-140	454.0	COG4948@1|root,COG4948@2|Bacteria,2JAZ6@203691|Spirochaetes	203691|Spirochaetes	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
CMS1_k127_1083380_1	926550.CLDAP_34550	7.221e-262	815.0	COG0318@1|root,COG0318@2|Bacteria,2G5XA@200795|Chloroflexi	200795|Chloroflexi	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
CMS1_k127_1083380_11	69395.JQLZ01000003_gene337	1.249e-72	257.0	COG4221@1|root,COG4221@2|Bacteria,1R83E@1224|Proteobacteria,2TVY6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS1_k127_1083380_17	926550.CLDAP_37450	3.04e-16	89.0	COG0454@1|root,COG0456@2|Bacteria,2G7CX@200795|Chloroflexi	200795|Chloroflexi	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS1_k127_1083380_6	926569.ANT_04070	1.867e-92	310.0	COG1349@1|root,COG1349@2|Bacteria,2G6FT@200795|Chloroflexi	200795|Chloroflexi	K	DeoR C terminal sensor domain	-	-	-	ko:K02081	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
CMS1_k127_1083380_7	485913.Krac_3684	3.452e-89	306.0	COG2222@1|root,COG2222@2|Bacteria,2G66K@200795|Chloroflexi	200795|Chloroflexi	M	SIS domain	-	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	SIS
CMS1_k127_1083380_13	697281.Mahau_2567	1.501e-51	201.0	COG2182@1|root,COG2182@2|Bacteria,1UW81@1239|Firmicutes,25MG2@186801|Clostridia,42IA7@68295|Thermoanaerobacterales	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1083380_8	697281.Mahau_2568	2.898e-82	284.0	COG0395@1|root,COG0395@2|Bacteria,1TSAB@1239|Firmicutes,25C5T@186801|Clostridia,42JEU@68295|Thermoanaerobacterales	186801|Clostridia	P	COGs COG0395 ABC-type sugar transport system permease component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_1083380_5	697281.Mahau_2566	8.207e-108	358.0	COG1175@1|root,COG1175@2|Bacteria,1TPTZ@1239|Firmicutes,2492R@186801|Clostridia,42FXR@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_1083380_15	311403.Arad_7878	6.701e-27	119.0	COG5285@1|root,COG5285@2|Bacteria,1N31I@1224|Proteobacteria,2U12W@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	1.14.11.46	ko:K21195	ko00440,map00440	-	R10724	RC01107	ko00000,ko00001,ko01000	-	-	-	PhyH
CMS1_k127_1083380_14	926550.CLDAP_23100	5.341e-40	153.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
CMS1_k127_108646_0	1382306.JNIM01000001_gene3678	1.107e-53	196.0	COG0501@1|root,COG0501@2|Bacteria,2G6KE@200795|Chloroflexi	200795|Chloroflexi	O	PFAM peptidase M48 Ste24p	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
CMS1_k127_108646_1	1379270.AUXF01000001_gene2571	1.737e-37	147.0	COG1986@1|root,COG1986@2|Bacteria,1ZUVB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	F	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions	-	-	-	-	-	-	-	-	-	-	-	-	NTPase_I-T
CMS1_k127_108646_4	316274.Haur_1638	2.051e-13	80.0	2F8YW@1|root,341AP@2|Bacteria,2GAD5@200795|Chloroflexi,375HY@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_108646_3	771875.Ferpe_2015	1.498e-15	90.0	COG0651@1|root,COG0651@2|Bacteria,2GBX5@200918|Thermotogae	200918|Thermotogae	C	plastoquinone (Complex I)	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iLJ478.TM1212	Proton_antipo_M
CMS1_k127_108646_2	909663.KI867150_gene2770	3.183e-27	124.0	COG3464@1|root,COG3464@2|Bacteria,1R8B7@1224|Proteobacteria	1224|Proteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	UPF0236
CMS1_k127_108646_5	383372.Rcas_2444	2.883e-08	59.0	2DQ8H@1|root,335A3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1091012_0	316274.Haur_3567	3.046e-125	412.0	COG1960@1|root,COG1960@2|Bacteria,2G5K3@200795|Chloroflexi,3752B@32061|Chloroflexia	32061|Chloroflexia	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS1_k127_1091012_1	497964.CfE428DRAFT_3727	2.002e-27	117.0	2FH6M@1|root,34912@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4203
CMS1_k127_1091012_2	243230.DR_1570	6.833e-10	62.0	COG0601@1|root,COG0601@2|Bacteria,1WIP3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_1093992_1	1122927.KB895414_gene5057	1.83e-29	130.0	COG1595@1|root,COG1595@2|Bacteria,1VIG7@1239|Firmicutes,4HTNK@91061|Bacilli,26U1D@186822|Paenibacillaceae	91061|Bacilli	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1093992_0	1120950.KB892780_gene389	1.964e-39	151.0	COG0178@1|root,COG0178@2|Bacteria,2GJUV@201174|Actinobacteria,4DN4J@85009|Propionibacteriales	2|Bacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
CMS1_k127_1096580_3	316274.Haur_2849	7.56e-11	66.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,2G88G@200795|Chloroflexi,37686@32061|Chloroflexia	2|Bacteria	O	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Laminin_G_3,Metallophos,Metallophos_C,PA,PKD,Peptidase_S8,Reprolysin_4
CMS1_k127_1096580_2	485913.Krac_11078	2.659e-40	157.0	COG2606@1|root,COG2606@2|Bacteria,2G73X@200795|Chloroflexi	200795|Chloroflexi	J	Aminoacyl-tRNA editing domain	-	-	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
CMS1_k127_1096580_1	479434.Sthe_0899	2.438e-94	321.0	COG3872@1|root,COG3872@2|Bacteria,2G5XQ@200795|Chloroflexi,27XQ4@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function (DUF1385)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1385
CMS1_k127_1096580_4	1301100.HG529382_gene4015	7.821e-05	53.0	COG3012@1|root,COG3012@2|Bacteria,1V8NE@1239|Firmicutes,25DYY@186801|Clostridia	186801|Clostridia	S	helix-turn-helix, Psq domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_psq,SEC-C
CMS1_k127_1096580_0	572477.Alvin_1133	1.337e-251	785.0	COG1866@1|root,COG1866@2|Bacteria,1MWXN@1224|Proteobacteria,1RPM0@1236|Gammaproteobacteria,1WWJT@135613|Chromatiales	135613|Chromatiales	H	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
CMS1_k127_1096804_0	926550.CLDAP_29610	4.044e-222	698.0	COG1904@1|root,COG1904@2|Bacteria,2G7Q1@200795|Chloroflexi	200795|Chloroflexi	G	Glucuronate isomerase	-	-	5.3.1.12	ko:K01812	ko00040,ko01100,map00040,map01100	M00061,M00631	R01482,R01983	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	UxaC
CMS1_k127_1096804_1	649638.Trad_0664	6.491e-98	331.0	COG1609@1|root,COG1609@2|Bacteria	2|Bacteria	K	purine nucleotide biosynthetic process	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
CMS1_k127_1097683_1	926550.CLDAP_01500	9.95e-65	239.0	COG0628@1|root,COG0628@2|Bacteria,2G6TV@200795|Chloroflexi	200795|Chloroflexi	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
CMS1_k127_1097683_6	351160.RCIX411	8.929e-08	53.0	COG0557@1|root,arCOG04686@2157|Archaea,2XT2E@28890|Euryarchaeota,2NA9N@224756|Methanomicrobia	224756|Methanomicrobia	K	PFAM ribonuclease II	-	-	3.1.13.1	ko:K01147	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNB
CMS1_k127_1097683_3	290315.Clim_1144	1.338e-47	173.0	COG1803@1|root,COG1803@2|Bacteria	2|Bacteria	G	methylglyoxal synthase activity	mgsA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008150,GO:0008152,GO:0008929,GO:0009058,GO:0009438,GO:0009987,GO:0016829,GO:0016835,GO:0016838,GO:0019242,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0071704,GO:1901576	4.2.3.3	ko:K01734	ko00640,ko01120,map00640,map01120	-	R01016	RC00424	ko00000,ko00001,ko01000	-	-	iECUMN_1333.ECUMN_1153,iYL1228.KPN_00992	MGS
CMS1_k127_1097683_5	518766.Rmar_2613	4.356e-12	68.0	COG0438@1|root,COG0438@2|Bacteria,4NIWP@976|Bacteroidetes	976|Bacteroidetes	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS1_k127_1097683_0	926569.ANT_20890	6.682e-199	637.0	COG0465@1|root,COG0465@2|Bacteria,2G5J3@200795|Chloroflexi	200795|Chloroflexi	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
CMS1_k127_1097683_4	1047013.AQSP01000122_gene2227	8.377e-29	120.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K02282,ko:K07705	ko02020,map02020	M00492	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	GerE,Response_reg,TauD
CMS1_k127_1097683_2	180332.JTGN01000024_gene1707	1.807e-56	212.0	COG0407@1|root,COG0407@2|Bacteria	180332.JTGN01000024_gene1707|-	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1105824_3	1250005.PHEL85_1991	6.947e-168	554.0	COG0265@1|root,COG0265@2|Bacteria,4PPSR@976|Bacteroidetes	976|Bacteroidetes	O	Chitobiase/beta-hexosaminidase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1
CMS1_k127_1105824_1	180332.JTGN01000005_gene2930	4.87e-200	636.0	COG3669@1|root,COG3669@2|Bacteria,1U9XH@1239|Firmicutes,24DER@186801|Clostridia	186801|Clostridia	G	Alpha-L-fucosidase	-	-	-	-	-	-	-	-	-	-	-	-	Alpha_L_fucos
CMS1_k127_1105824_6	717605.Theco_1689	8.012e-111	368.0	COG0667@1|root,COG0667@2|Bacteria,1UY4A@1239|Firmicutes,4HBZD@91061|Bacilli,26QWU@186822|Paenibacillaceae	91061|Bacilli	C	Oxidoreductase	yrpG	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS1_k127_1105824_10	1122223.KB890688_gene1616	5.383e-36	152.0	COG1653@1|root,COG1653@2|Bacteria,1WJIN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1
CMS1_k127_1105824_4	1499967.BAYZ01000040_gene2251	4.731e-145	465.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	fdh	-	1.1.1.316	ko:K17744	ko00053,ko01100,ko01110,map00053,map01100,map01110	M00114	R07675	RC00161	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldo_ket_red
CMS1_k127_1105824_2	44056.XP_009033642.1	9.52e-190	602.0	COG0160@1|root,KOG1403@2759|Eukaryota	2759|Eukaryota	E	ethanolamine-phosphate phospho-lyase activity	-	-	4.2.3.2	ko:K14286	ko00564,ko01100,map00564,map01100	-	R00748	RC00369	ko00000,ko00001,ko01000	-	-	-	Aminotran_3,Peptidase_M23
CMS1_k127_1105824_7	383372.Rcas_1244	8.12e-91	306.0	COG1524@1|root,COG1524@2|Bacteria	2|Bacteria	S	mannose-ethanolamine phosphotransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,PA14,Phosphodiest
CMS1_k127_1105824_12	1173022.Cri9333_3987	6.855e-29	125.0	COG1357@1|root,COG1357@2|Bacteria,1G1VX@1117|Cyanobacteria,1H90B@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
CMS1_k127_1105824_0	471870.BACINT_00905	1.064e-265	841.0	COG3808@1|root,COG3808@2|Bacteria,4NF2I@976|Bacteroidetes,2FM7F@200643|Bacteroidia,4AKW4@815|Bacteroidaceae	976|Bacteroidetes	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase,OmpA
CMS1_k127_1105824_9	357808.RoseRS_1546	1.521e-45	186.0	COG4447@1|root,COG4447@2|Bacteria,2G66V@200795|Chloroflexi,3767C@32061|Chloroflexia	32061|Chloroflexia	G	glycosyl hydrolase, BNR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1105824_5	926550.CLDAP_29640	3.354e-127	424.0	COG3664@1|root,COG3664@2|Bacteria,2GBKT@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycoside hydrolase family 39	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1105824_8	926550.CLDAP_35470	7.208e-90	316.0	COG3103@1|root,COG3858@1|root,COG3858@2|Bacteria,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	MA20_15015	-	-	-	-	-	-	-	-	-	-	-	DUF1236,SH3_3
CMS1_k127_1105824_11	246194.CHY_0607	9.418e-36	140.0	COG0346@1|root,COG0346@2|Bacteria,1V235@1239|Firmicutes,24G5W@186801|Clostridia	186801|Clostridia	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS1_k127_1106291_2	926550.CLDAP_32740	8.496e-140	450.0	COG0243@1|root,COG0243@2|Bacteria,2G5X7@200795|Chloroflexi	2|Bacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	bisC	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CMS1_k127_1106291_5	1380394.JADL01000001_gene2567	7.065e-76	259.0	COG0028@1|root,COG0028@2|Bacteria,1R6QP@1224|Proteobacteria,2TXAJ@28211|Alphaproteobacteria,2JWX2@204441|Rhodospirillales	204441|Rhodospirillales	EH	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C
CMS1_k127_1106291_6	1380394.JADL01000001_gene2568	5.71e-68	238.0	COG4032@1|root,COG4032@2|Bacteria,1P0HU@1224|Proteobacteria,2TRJ2@28211|Alphaproteobacteria,2JS9A@204441|Rhodospirillales	204441|Rhodospirillales	S	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_N
CMS1_k127_1106291_4	1380394.JADL01000009_gene3144	4.078e-78	271.0	COG3391@1|root,COG3391@2|Bacteria,1NT97@1224|Proteobacteria,2TWGD@28211|Alphaproteobacteria,2JXDQ@204441|Rhodospirillales	204441|Rhodospirillales	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
CMS1_k127_1106291_3	192952.MM_1949	1.141e-102	341.0	arCOG01778@1|root,arCOG01778@2157|Archaea,2XU6W@28890|Euryarchaeota,2N9ES@224756|Methanomicrobia	224756|Methanomicrobia	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
CMS1_k127_1106291_0	479434.Sthe_1421	2.748e-226	708.0	COG0055@1|root,COG0055@2|Bacteria,2G5JI@200795|Chloroflexi,27XYE@189775|Thermomicrobia	189775|Thermomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
CMS1_k127_1106291_8	1196323.ALKF01000186_gene5729	4.906e-47	180.0	COG0583@1|root,COG0583@2|Bacteria,1TRJK@1239|Firmicutes,4HAVD@91061|Bacilli,26QTW@186822|Paenibacillaceae	91061|Bacilli	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS1_k127_1106291_10	383372.Rcas_4098	1.181e-21	99.0	COG1366@1|root,COG1366@2|Bacteria,2G9K5@200795|Chloroflexi,375MW@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Sulfate transporter antisigma-factor antagonist STAS	-	-	-	-	-	-	-	-	-	-	-	-	STAS
CMS1_k127_1106291_7	357808.RoseRS_1153	1.726e-52	195.0	COG0483@1|root,COG0483@2|Bacteria,2G92C@200795|Chloroflexi,375IY@32061|Chloroflexia	32061|Chloroflexia	G	PFAM inositol monophosphatase	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
CMS1_k127_1106291_9	237368.SCABRO_03556	1.501e-32	142.0	COG1357@1|root,COG1357@2|Bacteria,2J0M1@203682|Planctomycetes	203682|Planctomycetes	S	Pentapeptide repeats (9 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
CMS1_k127_1106291_1	316274.Haur_2040	1.801e-148	514.0	COG0457@1|root,COG4783@1|root,COG0457@2|Bacteria,COG4783@2|Bacteria,2G71Q@200795|Chloroflexi,376GZ@32061|Chloroflexia	2|Bacteria	NU	SMART Tetratricopeptide domain protein	-	-	2.7.11.1,3.6.4.12	ko:K03654,ko:K11935,ko:K14949,ko:K21007	ko02025,ko02026,ko03018,ko05152,map02025,map02026,map03018,map05152	-	-	-	ko00000,ko00001,ko01000,ko01001,ko03400	-	-	-	Pkinase,PknG_TPR,PknG_rubred,TPR_15,TPR_16,TPR_19
CMS1_k127_1109774_0	1033743.CAES01000078_gene3768	2.421e-124	404.0	COG0111@1|root,COG0111@2|Bacteria,1U2XG@1239|Firmicutes,4HF1I@91061|Bacilli,26VA2@186822|Paenibacillaceae	91061|Bacilli	EH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
CMS1_k127_1109774_5	1382306.JNIM01000001_gene1109	9.713e-05	50.0	2F64E@1|root,33YNP@2|Bacteria	2|Bacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,MDMPI_N
CMS1_k127_1109774_1	926550.CLDAP_07100	2.087e-104	344.0	COG1024@1|root,COG1024@2|Bacteria,2G5JW@200795|Chloroflexi	200795|Chloroflexi	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS1_k127_1109774_3	316274.Haur_3807	2.39e-60	215.0	COG0311@1|root,COG0311@2|Bacteria,2G6JN@200795|Chloroflexi,375M7@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
CMS1_k127_1109774_4	1521187.JPIM01000075_gene2847	4.353e-49	179.0	COG2258@1|root,COG2258@2|Bacteria	2|Bacteria	C	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
CMS1_k127_1109774_2	316274.Haur_0312	5.431e-102	345.0	COG4106@1|root,COG4106@2|Bacteria	2|Bacteria	FG	trans-aconitate 2-methyltransferase activity	-	-	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
CMS1_k127_1124695_0	1265505.ATUG01000002_gene1702	6.413e-118	390.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,42UHV@68525|delta/epsilon subdivisions,2WQCZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Predicted permease	-	-	-	-	-	-	-	-	-	-	-	-	ArsP_1
CMS1_k127_1124695_2	1121920.AUAU01000006_gene267	1.664e-33	134.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	arsR	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
CMS1_k127_1124695_1	1537994.JQFW01000056_gene798	1.078e-106	354.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,1RQGQ@1236|Gammaproteobacteria,46CR9@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS1_k127_1127016_1	1445613.JALM01000086_gene3301	1.484e-33	150.0	COG0601@1|root,COG0601@2|Bacteria,2GJ2C@201174|Actinobacteria,4DX8S@85010|Pseudonocardiales	201174|Actinobacteria	P	ABC-type dipeptide oligopeptide nickel transport system, permease component	dppB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_1127016_0	641491.DND132_0153	2.817e-36	157.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,42MFK@68525|delta/epsilon subdivisions,2WKBU@28221|Deltaproteobacteria,2M7XJ@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	extracellular solute-binding protein, family 5	-	-	-	ko:K02035,ko:K13893	ko02010,ko02024,map02010,map02024	M00239,M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
CMS1_k127_1127016_2	1476583.DEIPH_ctg002orf0039	1.268e-32	138.0	COG0639@1|root,COG0639@2|Bacteria,1WJXV@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
CMS1_k127_1127016_3	304371.MCP_0389	1.057e-23	113.0	arCOG11014@1|root,arCOG11014@2157|Archaea,2XZ0A@28890|Euryarchaeota	2157|Archaea	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
CMS1_k127_1128100_2	479434.Sthe_1792	3.866e-24	102.0	COG2030@1|root,COG2030@2|Bacteria,2G6YG@200795|Chloroflexi	200795|Chloroflexi	I	PFAM MaoC domain protein dehydratase	-	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009436,GO:0009987,GO:0015977,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043427,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0046395,GO:0046487,GO:0071704,GO:0072329,GO:1901575	4.2.1.148	ko:K14449	ko00630,ko00660,ko00720,ko01120,ko01200,map00630,map00660,map00720,map01120,map01200	M00373,M00376,M00740	R05076	RC01984	ko00000,ko00001,ko00002,ko01000	-	-	-	MaoC_dehydratas
CMS1_k127_1128100_1	314230.DSM3645_11227	9.258e-36	149.0	COG5625@1|root,COG5625@2|Bacteria	2|Bacteria	K	HemY protein N-terminus	lapA	-	-	ko:K12549	-	-	-	-	ko00000	-	-	-	Cadherin_3,Calx-beta,DUF4347,He_PIG,HemolysinCabind,VWA,VWA_2
CMS1_k127_1128100_0	1356854.N007_09035	4.806e-181	574.0	COG1228@1|root,COG1228@2|Bacteria,1TQQ0@1239|Firmicutes,4HDKW@91061|Bacilli	91061|Bacilli	Q	Imidazolonepropionase and related amidohydrolases	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
CMS1_k127_1128100_3	1121946.AUAX01000008_gene7362	2.189e-17	83.0	COG0492@1|root,COG0492@2|Bacteria,2GK62@201174|Actinobacteria,4D9VG@85008|Micromonosporales	201174|Actinobacteria	OT	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_3,Response_reg
CMS1_k127_1129698_1	926569.ANT_27450	1.683e-77	285.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2G790@200795|Chloroflexi	200795|Chloroflexi	T	Stage II sporulation E family protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,SpoIIE
CMS1_k127_1129698_2	926569.ANT_27440	2.962e-30	124.0	COG2172@1|root,COG2172@2|Bacteria,2G93H@200795|Chloroflexi	200795|Chloroflexi	T	PFAM Sulfate transporter antisigma-factor antagonist STAS	-	-	2.7.11.1	ko:K04749,ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2,STAS
CMS1_k127_1129698_3	926569.ANT_27430	1.374e-27	115.0	COG1366@1|root,COG1366@2|Bacteria,2G9DJ@200795|Chloroflexi	200795|Chloroflexi	T	PFAM Sulfate transporter antisigma-factor antagonist STAS	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
CMS1_k127_1129698_0	926550.CLDAP_12670	3.758e-115	387.0	COG3307@1|root,COG3307@2|Bacteria,2G6B1@200795|Chloroflexi	200795|Chloroflexi	M	PFAM O-antigen polymerase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
CMS1_k127_1137035_5	926569.ANT_25160	3.19e-23	103.0	COG0612@1|root,COG0612@2|Bacteria,2G68H@200795|Chloroflexi	200795|Chloroflexi	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
CMS1_k127_1137035_2	909663.KI867150_gene1369	7.872e-120	402.0	COG4262@1|root,COG4262@2|Bacteria,1QUK8@1224|Proteobacteria,42SZH@68525|delta/epsilon subdivisions,2WPX7@28221|Deltaproteobacteria,2MQHU@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
CMS1_k127_1137035_6	326427.Cagg_1682	4.105e-23	103.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	MA20_23570	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_34
CMS1_k127_1137035_1	1210884.HG799469_gene14132	4.618e-129	419.0	COG0039@1|root,COG0039@2|Bacteria,2IYB4@203682|Planctomycetes	203682|Planctomycetes	C	Belongs to the LDH MDH superfamily	ldh	-	1.1.1.27	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	-	R00703,R01000,R03104	RC00031,RC00044	ko00000,ko00001,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
CMS1_k127_1137035_7	383372.Rcas_2521	5.862e-06	59.0	COG1716@1|root,COG1716@2|Bacteria,2G9KV@200795|Chloroflexi,376M0@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA
CMS1_k127_1137035_4	926550.CLDAP_10530	4.75e-25	122.0	COG0457@1|root,COG0823@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,2G8PZ@200795|Chloroflexi	200795|Chloroflexi	U	WD40 domain protein beta Propeller	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
CMS1_k127_1137035_0	926550.CLDAP_31240	6.94e-205	647.0	COG1032@1|root,COG1032@2|Bacteria,2G6ZI@200795|Chloroflexi	200795|Chloroflexi	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
CMS1_k127_1137035_3	883112.HMPREF9707_00879	1.269e-61	217.0	COG2313@1|root,COG2313@2|Bacteria,1TR5J@1239|Firmicutes,4HC38@91061|Bacilli	91061|Bacilli	Q	Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway	psuG	-	4.2.1.70	ko:K16329	ko00240,map00240	-	R01055	RC00432,RC00433	ko00000,ko00001,ko01000	-	-	-	Indigoidine_A
CMS1_k127_1139237_10	246194.CHY_0193	7.34e-40	151.0	COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,248ZN@186801|Clostridia,42EXR@68295|Thermoanaerobacterales	186801|Clostridia	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
CMS1_k127_1139237_6	926550.CLDAP_23250	2.018e-65	234.0	COG0500@1|root,COG2226@2|Bacteria,2G9CY@200795|Chloroflexi	200795|Chloroflexi	Q	Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS1_k127_1139237_7	1123504.JQKD01000030_gene4596	3.612e-57	205.0	COG2020@1|root,COG2020@2|Bacteria,1N3YJ@1224|Proteobacteria,2VT4V@28216|Betaproteobacteria,4AFU0@80864|Comamonadaceae	28216|Betaproteobacteria	O	Ergosterol biosynthesis ERG4/ERG24 family	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
CMS1_k127_1139237_9	1122925.KB895385_gene2974	6.265e-40	157.0	COG4262@1|root,COG4262@2|Bacteria,1V555@1239|Firmicutes,4HI5Z@91061|Bacilli,26WGU@186822|Paenibacillaceae	91061|Bacilli	S	Spermine/spermidine synthase domain	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
CMS1_k127_1139237_4	287986.DV20_11530	1.198e-115	378.0	COG0684@1|root,COG0684@2|Bacteria,2I4DD@201174|Actinobacteria,4E9Y8@85010|Pseudonocardiales	201174|Actinobacteria	H	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
CMS1_k127_1139237_8	452637.Oter_3829	4.666e-52	201.0	COG1524@1|root,COG1524@2|Bacteria,46VXF@74201|Verrucomicrobia,3K93S@414999|Opitutae	414999|Opitutae	S	Metalloenzyme superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
CMS1_k127_1139237_12	56110.Oscil6304_0817	1.48e-33	131.0	COG2929@1|root,COG2929@2|Bacteria,1G92M@1117|Cyanobacteria,1HCTJ@1150|Oscillatoriales	1117|Cyanobacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
CMS1_k127_1139237_13	391612.CY0110_27475	8.694e-30	122.0	2C6B2@1|root,3318T@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1139237_14	1444712.BN1013_01784	3.386e-17	83.0	COG0789@1|root,COG0789@2|Bacteria,2JHDQ@204428|Chlamydiae	204428|Chlamydiae	K	MerR HTH family regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	MerR
CMS1_k127_1139237_5	941449.dsx2_1110	1.436e-80	276.0	COG4976@1|root,COG4976@2|Bacteria	2|Bacteria	O	Methyltransferase	-	-	-	ko:K16437,ko:K20331,ko:K21336	ko00523,ko01055,ko01130,ko02024,map00523,map01055,map01130,map02024	-	R06627,R11466	RC00003,RC01654,RC03444	ko00000,ko00001,ko01000	-	-	-	Methyltransf_11,Methyltransf_13,Methyltransf_14,Methyltransf_23,Methyltransf_25
CMS1_k127_1139237_1	926550.CLDAP_18660	1.656e-170	541.0	COG0535@1|root,COG0535@2|Bacteria,2G7WG@200795|Chloroflexi	200795|Chloroflexi	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
CMS1_k127_1139237_2	926550.CLDAP_18650	3.203e-170	547.0	COG1032@1|root,COG1032@2|Bacteria,2G6ZI@200795|Chloroflexi	2|Bacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,Radical_SAM
CMS1_k127_1139237_0	926550.CLDAP_18640	5.508e-234	732.0	COG1032@1|root,COG1032@2|Bacteria,2G6ZI@200795|Chloroflexi	2|Bacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,Radical_SAM
CMS1_k127_1139237_11	926550.CLDAP_18610	2.575e-36	141.0	COG0316@1|root,COG0316@2|Bacteria,2G705@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the HesB IscA family	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
CMS1_k127_1139237_3	926550.CLDAP_18560	1.229e-117	382.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
CMS1_k127_1140145_0	383372.Rcas_2214	1.188e-18	89.0	COG1195@1|root,COG1195@2|Bacteria,2G60N@200795|Chloroflexi,375E0@32061|Chloroflexia	32061|Chloroflexia	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
CMS1_k127_1140145_1	760192.Halhy_1346	1.67e-18	100.0	COG1404@1|root,COG1404@2|Bacteria,4NKF4@976|Bacteroidetes	976|Bacteroidetes	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
CMS1_k127_1146774_14	5507.FOXG_02530P0	2.898e-11	73.0	COG3836@1|root,2QR7H@2759|Eukaryota,39RYT@33154|Opisthokonta,3NVCB@4751|Fungi,3QSTY@4890|Ascomycota,21I32@147550|Sordariomycetes,3TR2M@5125|Hypocreales,1FSUH@110618|Nectriaceae	4751|Fungi	G	HpcH/HpaI aldolase/citrate lyase family	-	-	4.1.2.52	ko:K02510	ko00350,ko01120,map00350,map01120	-	R01645,R01647	RC00307,RC00572,RC00574,RC03057	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
CMS1_k127_1146774_15	1172181.KB911721_gene3817	0.0004795	46.0	COG1609@1|root,COG1609@2|Bacteria,2GMGS@201174|Actinobacteria	201174|Actinobacteria	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
CMS1_k127_1146774_1	42256.RradSPS_0358	2.645e-198	651.0	COG2909@1|root,COG2909@2|Bacteria,2HENR@201174|Actinobacteria,4CPC9@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,AAA_22,GerE
CMS1_k127_1146774_12	485913.Krac_4110	4.671e-16	80.0	2DRAK@1|root,33AYS@2|Bacteria	485913.Krac_4110|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1146774_4	448385.sce5740	1.469e-105	372.0	COG2234@1|root,COG2234@2|Bacteria,1R56X@1224|Proteobacteria,43823@68525|delta/epsilon subdivisions,2X3C5@28221|Deltaproteobacteria,2YVD0@29|Myxococcales	28221|Deltaproteobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
CMS1_k127_1146774_5	189425.PGRAT_04425	8.538e-82	294.0	COG0793@1|root,COG0793@2|Bacteria,1VSAT@1239|Firmicutes,4IA3K@91061|Bacilli,272BH@186822|Paenibacillaceae	91061|Bacilli	M	tail specific protease	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S41
CMS1_k127_1146774_3	926550.CLDAP_29890	2.788e-110	368.0	COG4277@1|root,COG4277@2|Bacteria,2G5JR@200795|Chloroflexi	200795|Chloroflexi	S	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	HHH_3,Radical_SAM
CMS1_k127_1146774_10	765420.OSCT_0609	1.689e-36	145.0	COG1514@1|root,COG1514@2|Bacteria,2G76S@200795|Chloroflexi,375YZ@32061|Chloroflexia	32061|Chloroflexia	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
CMS1_k127_1146774_7	926550.CLDAP_23380	4.95e-68	250.0	COG0004@1|root,COG0004@2|Bacteria,2G5N8@200795|Chloroflexi	2|Bacteria	P	PFAM Rh family protein ammonium transporter	amt	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
CMS1_k127_1146774_13	1128421.JAGA01000002_gene182	5.213e-14	76.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	DZR,FHA,zinc_ribbon_2
CMS1_k127_1146774_11	1382306.JNIM01000001_gene1619	8.694e-30	122.0	COG0799@1|root,COG0799@2|Bacteria,2G77A@200795|Chloroflexi	200795|Chloroflexi	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
CMS1_k127_1146774_0	383372.Rcas_2799	0.0	1418.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,2G64C@200795|Chloroflexi,376K3@32061|Chloroflexia	32061|Chloroflexia	M	Tricorn protease homolog	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
CMS1_k127_1146774_8	1382306.JNIM01000001_gene284	6.88e-67	242.0	COG2120@1|root,COG2120@2|Bacteria,2G6W3@200795|Chloroflexi	200795|Chloroflexi	S	PFAM LmbE family protein	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
CMS1_k127_1146774_6	28072.Nos7524_2198	5.171e-70	247.0	28I2M@1|root,2Z86P@2|Bacteria,1G2A6@1117|Cyanobacteria,1HJA4@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function (DUF4058)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4058
CMS1_k127_1146774_2	498761.HM1_1745	1.005e-164	534.0	COG3383@1|root,COG3383@2|Bacteria,1UI1F@1239|Firmicutes,25EAG@186801|Clostridia	186801|Clostridia	C	Molybdopterin oxidoreductase, Fe4S4	-	-	1.17.1.10,1.6.5.3	ko:K00336,ko:K05299	ko00190,ko00680,ko00720,ko01100,ko01120,ko01200,map00190,map00680,map00720,map01100,map01120,map01200	M00144,M00377	R00134,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Fer4,Fer4_6,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
CMS1_k127_1146774_9	1122611.KB903975_gene3211	5.538e-55	198.0	COG3383@1|root,COG3383@2|Bacteria,2HC9H@201174|Actinobacteria,4EGXK@85012|Streptosporangiales	201174|Actinobacteria	C	Molybdopterin oxidoreductase	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Fer4_7,Fer4_9,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
CMS1_k127_115041_4	134676.ACPL_1625	1.726e-60	226.0	COG1994@1|root,COG1994@2|Bacteria,2GM8E@201174|Actinobacteria,4D8XB@85008|Micromonosporales	201174|Actinobacteria	S	Peptidase M50	rip2	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
CMS1_k127_115041_0	1173028.ANKO01000074_gene3009	9.92e-191	633.0	COG0642@1|root,COG0745@1|root,COG2202@1|root,COG3437@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3437@2|Bacteria,1G09B@1117|Cyanobacteria,1H7M4@1150|Oscillatoriales	1117|Cyanobacteria	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain	-	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	CBS,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
CMS1_k127_115041_1	1173027.Mic7113_4322	6.875e-143	487.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1H7M4@1150|Oscillatoriales	1117|Cyanobacteria	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
CMS1_k127_115041_5	218284.CCDN010000002_gene2209	2.366e-60	221.0	COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,4HBCY@91061|Bacilli,1ZCTZ@1386|Bacillus	91061|Bacilli	S	ABC transporter substrate-binding protein PnrA-like	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
CMS1_k127_115041_3	485913.Krac_3511	1.093e-109	365.0	COG2378@1|root,COG2378@2|Bacteria	2|Bacteria	K	regulation of single-species biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
CMS1_k127_115041_2	1068980.ARVW01000001_gene6489	4.365e-115	383.0	COG0477@1|root,COG2814@2|Bacteria,2IDPG@201174|Actinobacteria	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
CMS1_k127_1151521_1	926569.ANT_11000	3.381e-124	426.0	COG1933@1|root,COG2114@1|root,COG3899@1|root,COG1933@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2G699@200795|Chloroflexi	200795|Chloroflexi	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
CMS1_k127_1151521_0	926550.CLDAP_05470	1.79e-164	536.0	COG4888@1|root,COG4888@2|Bacteria,2G838@200795|Chloroflexi	2|Bacteria	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP,UnbV_ASPIC,VCBS
CMS1_k127_1151521_4	383372.Rcas_3613	1.02e-70	244.0	COG2085@1|root,COG2085@2|Bacteria,2G7DD@200795|Chloroflexi	200795|Chloroflexi	S	NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
CMS1_k127_1151521_3	926550.CLDAP_38360	3.902e-97	328.0	COG0395@1|root,COG0395@2|Bacteria,2G8QJ@200795|Chloroflexi	200795|Chloroflexi	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_1151521_2	926550.CLDAP_38370	3.254e-106	355.0	COG1175@1|root,COG1175@2|Bacteria	2|Bacteria	P	transmembrane transport	-	-	-	ko:K02025,ko:K05814,ko:K10118,ko:K10237,ko:K10241,ko:K15771,ko:K17235,ko:K17242,ko:K17316	ko02010,map02010	M00196,M00198,M00204,M00206,M00207,M00491,M00600,M00602,M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.17,3.A.1.1.2,3.A.1.1.23,3.A.1.1.24,3.A.1.1.28,3.A.1.1.3,3.A.1.1.30,3.A.1.1.34,3.A.1.1.39	-	-	BPD_transp_1
CMS1_k127_1158654_2	880070.Cycma_1926	5.572e-33	138.0	COG3618@1|root,COG3618@2|Bacteria,4P1FE@976|Bacteroidetes,47UAG@768503|Cytophagia	976|Bacteroidetes	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CMS1_k127_1158654_0	1288963.ADIS_3902	2.235e-76	266.0	COG1028@1|root,COG1028@2|Bacteria,4NFU6@976|Bacteroidetes,47KT7@768503|Cytophagia	976|Bacteroidetes	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	1.1.1.100,1.1.1.159	ko:K00059,ko:K00076	ko00061,ko00121,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00121,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS1_k127_1158654_1	1499967.BAYZ01000141_gene6155	1.254e-34	135.0	COG2442@1|root,COG2442@2|Bacteria	2|Bacteria	K	InterPro IPR007367	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
CMS1_k127_1158654_4	1499968.TCA2_3429	2.189e-14	78.0	COG0494@1|root,COG0494@2|Bacteria,1UMYB@1239|Firmicutes,4IU37@91061|Bacilli,26XP1@186822|Paenibacillaceae	91061|Bacilli	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS1_k127_1158654_3	1268072.PSAB_11350	4.334e-31	130.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	2.3.1.128,2.3.1.256	ko:K00670,ko:K03789	-	-	-	-	ko00000,ko01000,ko03009,ko04131	-	-	-	Acetyltransf_1
CMS1_k127_1164721_4	926569.ANT_18200	2.56e-130	425.0	COG0489@1|root,COG0489@2|Bacteria,2G60P@200795|Chloroflexi	200795|Chloroflexi	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
CMS1_k127_1164721_8	1449063.JMLS01000002_gene1242	7.362e-47	176.0	COG2345@1|root,COG2345@2|Bacteria,1V5Q5@1239|Firmicutes,4HHMX@91061|Bacilli,26U3B@186822|Paenibacillaceae	91061|Bacilli	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,HTH_20,HTH_24,HTH_5,HTH_DeoR
CMS1_k127_1164721_6	479434.Sthe_1522	1.199e-104	346.0	COG0396@1|root,COG0396@2|Bacteria,2G5S6@200795|Chloroflexi,27XVN@189775|Thermomicrobia	189775|Thermomicrobia	O	ATPases associated with a variety of cellular activities	-	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
CMS1_k127_1164721_0	525904.Tter_1698	1.809e-234	732.0	COG0719@1|root,COG0719@2|Bacteria,2NNKT@2323|unclassified Bacteria	2|Bacteria	O	FeS assembly protein SufB	sufB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360	-	ko:K07033,ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
CMS1_k127_1164721_7	309801.trd_0379	3.799e-101	345.0	COG0719@1|root,COG0719@2|Bacteria,2G5S8@200795|Chloroflexi,27Y27@189775|Thermomicrobia	189775|Thermomicrobia	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
CMS1_k127_1164721_3	383372.Rcas_0312	1.619e-141	453.0	COG2897@1|root,COG2897@2|Bacteria,2G5XI@200795|Chloroflexi,374RX@32061|Chloroflexia	32061|Chloroflexia	P	PFAM Rhodanese domain protein	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
CMS1_k127_1164721_1	1382306.JNIM01000001_gene4003	1.103e-166	533.0	COG0520@1|root,COG0520@2|Bacteria,2G5T3@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
CMS1_k127_1164721_9	525904.Tter_1695	9.306e-46	168.0	COG0822@1|root,COG0822@2|Bacteria,2NPXN@2323|unclassified Bacteria	2|Bacteria	C	NifU-like N terminal domain	nifU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
CMS1_k127_1164721_10	886293.Sinac_5289	9.198e-27	112.0	COG2146@1|root,COG2146@2|Bacteria,2J13Z@203682|Planctomycetes	203682|Planctomycetes	C	of nitrite reductase and ring-hydroxylating	-	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
CMS1_k127_1164721_12	926569.ANT_18000	1.498e-14	77.0	COG2151@1|root,COG2151@2|Bacteria,2G9UF@200795|Chloroflexi	200795|Chloroflexi	S	Pfam:DUF59	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
CMS1_k127_1164721_11	502025.Hoch_4177	2.453e-26	110.0	COG1977@1|root,COG1977@2|Bacteria,1N4Z0@1224|Proteobacteria,43B8K@68525|delta/epsilon subdivisions,2X6MX@28221|Deltaproteobacteria,2Z3BT@29|Myxococcales	28221|Deltaproteobacteria	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
CMS1_k127_1164721_2	926550.CLDAP_00500	1.788e-166	531.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,2G5TN@200795|Chloroflexi	200795|Chloroflexi	HP	PFAM UBA THIF-type NAD FAD binding protein	-	-	2.7.7.80,2.8.1.11	ko:K21029,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
CMS1_k127_1164721_5	247490.KSU1_D0611	2.521e-110	365.0	COG0031@1|root,COG0031@2|Bacteria,2J2DP@203682|Planctomycetes	203682|Planctomycetes	E	Pyridoxal-phosphate dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	PALP
CMS1_k127_1168601_1	552811.Dehly_1236	1.687e-106	359.0	COG0016@1|root,COG0016@2|Bacteria,2G5T1@200795|Chloroflexi,34CPK@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
CMS1_k127_1168601_3	357808.RoseRS_1314	2.317e-10	70.0	COG0457@1|root,COG0457@2|Bacteria,2GB8I@200795|Chloroflexi,377JS@32061|Chloroflexia	32061|Chloroflexia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1168601_2	926550.CLDAP_35100	4.085e-102	346.0	COG1721@1|root,COG1721@2|Bacteria,2G5XH@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CMS1_k127_1168601_0	1128421.JAGA01000002_gene222	1.648e-143	461.0	COG0714@1|root,COG0714@2|Bacteria,2NNMQ@2323|unclassified Bacteria	2|Bacteria	S	ATPase associated with various cellular	moxR1	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS1_k127_118868_2	485913.Krac_10791	2.274e-89	303.0	COG4012@1|root,COG4012@2|Bacteria,2G6IF@200795|Chloroflexi	200795|Chloroflexi	S	Putative pyruvate format-lyase activating enzyme (DUF1786)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1786
CMS1_k127_118868_3	1206732.BAGD01000032_gene983	1.07e-41	161.0	COG3576@1|root,COG3576@2|Bacteria,2I3R7@201174|Actinobacteria,4G1T9@85025|Nocardiaceae	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
CMS1_k127_118868_1	234267.Acid_5088	6.249e-214	676.0	COG1012@1|root,COG1012@2|Bacteria,3Y3CY@57723|Acidobacteria	57723|Acidobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS1_k127_118868_0	324602.Caur_0578	3.949e-247	783.0	COG2217@1|root,COG2217@2|Bacteria,2G5J7@200795|Chloroflexi,3756S@32061|Chloroflexia	32061|Chloroflexia	P	TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
CMS1_k127_1190217_0	402777.KB235904_gene4108	1.59e-218	719.0	COG0515@1|root,COG2203@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,PAS_3,Pkinase,Response_reg
CMS1_k127_1190217_4	383372.Rcas_3261	8.412e-43	182.0	COG4585@1|root,COG4585@2|Bacteria,2G90K@200795|Chloroflexi,376BE@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA_3
CMS1_k127_1190217_2	1521187.JPIM01000045_gene1439	7.712e-60	227.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
CMS1_k127_1190217_1	262724.TT_C0987	9.611e-67	247.0	COG2197@1|root,COG2197@2|Bacteria,1WI4W@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS1_k127_1190217_3	1123389.ATXJ01000005_gene1971	5.863e-44	164.0	COG2197@1|root,COG2197@2|Bacteria,1WI4W@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS1_k127_1198940_2	485913.Krac_2635	1.45e-76	266.0	COG0457@1|root,COG3629@1|root,COG3899@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG3899@2|Bacteria,2G871@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,TPR_12
CMS1_k127_1198940_3	1237149.C900_05711	8.203e-71	250.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS1_k127_1198940_4	1128427.KB904821_gene4651	1.482e-14	85.0	COG1357@1|root,COG1357@2|Bacteria,1G9R2@1117|Cyanobacteria,1HDA8@1150|Oscillatoriales	1117|Cyanobacteria	S	Pentapeptide repeats (9 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
CMS1_k127_1198940_1	926550.CLDAP_30280	1.208e-102	343.0	COG2971@1|root,COG2971@2|Bacteria,2G6Y6@200795|Chloroflexi	200795|Chloroflexi	G	BadF/BadG/BcrA/BcrD ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
CMS1_k127_1198940_0	926550.CLDAP_30290	2.503e-139	447.0	COG1482@1|root,COG1482@2|Bacteria	2|Bacteria	G	cell wall glycoprotein biosynthetic process	-	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
CMS1_k127_1205935_3	926550.CLDAP_39750	1.101e-71	270.0	COG3463@1|root,COG3463@2|Bacteria,2G8G9@200795|Chloroflexi	200795|Chloroflexi	S	Predicted membrane protein (DUF2079)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2079
CMS1_k127_1205935_7	926550.CLDAP_11920	6.805e-09	69.0	COG2132@1|root,COG5617@1|root,COG2132@2|Bacteria,COG5617@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	-	-	1.16.3.3,1.7.2.1	ko:K00368,ko:K07233,ko:K22349	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Cu-oxidase_3,PTPS_related
CMS1_k127_1205935_5	1396141.BATP01000060_gene4657	7.972e-22	112.0	COG2010@1|root,COG2312@1|root,COG3204@1|root,COG2010@2|Bacteria,COG2312@2|Bacteria,COG3204@2|Bacteria	2|Bacteria	L	pilus organization	-	-	-	ko:K02305	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002	3.D.4.10	-	-	CHB_HEX_C_1,CotH,Erythro_esteras,Fn3_assoc,LTD,Laminin_G_3
CMS1_k127_1205935_0	1396141.BATP01000057_gene3053	6.553e-151	512.0	COG2312@1|root,COG3209@1|root,COG2312@2|Bacteria,COG3209@2|Bacteria,46XD5@74201|Verrucomicrobia,2IVHX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Fn3_assoc,LTD
CMS1_k127_1205935_1	879212.DespoDRAFT_02837	2.051e-131	430.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42MTX@68525|delta/epsilon subdivisions,2WITE@28221|Deltaproteobacteria,2MK2A@213118|Desulfobacterales	28221|Deltaproteobacteria	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
CMS1_k127_1205935_4	589865.DaAHT2_0364	3.813e-31	133.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,42M3E@68525|delta/epsilon subdivisions,2WKMK@28221|Deltaproteobacteria,2MI0Y@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
CMS1_k127_1205935_2	926550.CLDAP_21460	2.353e-77	268.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2,GtrA
CMS1_k127_1205935_6	926550.CLDAP_04470	1.215e-21	98.0	COG1807@1|root,COG1807@2|Bacteria,2G9RZ@200795|Chloroflexi	200795|Chloroflexi	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1227052_1	1380394.JADL01000001_gene2217	1.703e-160	529.0	COG0747@1|root,COG0747@2|Bacteria,1MU3P@1224|Proteobacteria,2TT4M@28211|Alphaproteobacteria,2JQRE@204441|Rhodospirillales	204441|Rhodospirillales	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_1227052_3	1380394.JADL01000001_gene2216	1.252e-133	432.0	COG0601@1|root,COG0601@2|Bacteria,1MWXF@1224|Proteobacteria,2TR7C@28211|Alphaproteobacteria,2JQ7B@204441|Rhodospirillales	204441|Rhodospirillales	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_1227052_2	1380394.JADL01000001_gene2215	1.324e-145	470.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,2TUWG@28211|Alphaproteobacteria,2JQ92@204441|Rhodospirillales	204441|Rhodospirillales	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
CMS1_k127_1227052_0	396014.BF93_08225	1.959e-230	733.0	COG1123@1|root,COG4172@2|Bacteria,2H3HY@201174|Actinobacteria,4FBI8@85020|Dermabacteraceae	201174|Actinobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
CMS1_k127_1227052_5	1089544.KB912942_gene6126	2.815e-15	79.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4DXJW@85010|Pseudonocardiales	201174|Actinobacteria	K	transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,NB-ARC,TPR_12,Trans_reg_C
CMS1_k127_1227052_6	105420.BBPO01000005_gene2881	2.434e-13	72.0	COG1414@1|root,COG1414@2|Bacteria,2GM23@201174|Actinobacteria,2NHGX@228398|Streptacidiphilus	201174|Actinobacteria	K	helix_turn_helix isocitrate lyase regulation	allR	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
CMS1_k127_1227052_4	1089553.Tph_c27670	1.643e-59	213.0	COG5012@1|root,COG5012@2|Bacteria,1V1P0@1239|Firmicutes,24G08@186801|Clostridia,42FJI@68295|Thermoanaerobacterales	186801|Clostridia	S	Methionine synthase B12-binding module cap domain protein	-	-	2.1.1.13	ko:K00548,ko:K14084	ko00270,ko00450,ko00670,ko00680,ko01100,ko01110,ko01120,ko01200,ko01230,map00270,map00450,map00670,map00680,map01100,map01110,map01120,map01200,map01230	M00017,M00563	R00946,R09124,R09365	RC00035,RC00113,RC00732,RC01241,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2
CMS1_k127_1227052_7	1047013.AQSP01000134_gene1338	2.544e-07	57.0	COG5598@1|root,COG5598@2|Bacteria,2NQTC@2323|unclassified Bacteria	2|Bacteria	H	Trimethylamine methyltransferase (MTTB)	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
CMS1_k127_1249299_0	479434.Sthe_1110	2.179e-134	439.0	COG1190@1|root,COG1190@2|Bacteria,2G65Z@200795|Chloroflexi,27XMG@189775|Thermomicrobia	189775|Thermomicrobia	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
CMS1_k127_1249299_3	1051501.AYTL01000030_gene2808	1.1e-44	166.0	COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,4HGZU@91061|Bacilli,1ZFQI@1386|Bacillus	91061|Bacilli	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
CMS1_k127_1249299_2	926550.CLDAP_13220	2.593e-52	192.0	COG1842@1|root,COG1842@2|Bacteria	2|Bacteria	KT	Phage shock protein A	-	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	Peptidase_M23,PspA_IM30
CMS1_k127_1249299_1	926550.CLDAP_16480	8.737e-63	226.0	COG0745@1|root,COG1672@1|root,COG0745@2|Bacteria,COG1672@2|Bacteria,2G778@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
CMS1_k127_1249819_0	697281.Mahau_1296	1.942e-83	289.0	COG0407@1|root,COG0407@2|Bacteria,1V4YU@1239|Firmicutes,24FCZ@186801|Clostridia,42HY1@68295|Thermoanaerobacterales	186801|Clostridia	H	PFAM Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
CMS1_k127_1249819_1	1226325.HMPREF1548_02962	2.062e-31	126.0	2BDHS@1|root,3276Z@2|Bacteria,1UT2X@1239|Firmicutes,2511Q@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1249819_2	517417.Cpar_2037	9.925e-25	115.0	COG0500@1|root,COG2226@2|Bacteria,1FE72@1090|Chlorobi	1090|Chlorobi	H	UbiE COQ5	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS1_k127_1249819_4	118161.KB235922_gene2451	0.0002609	48.0	2DUHW@1|root,33QRK@2|Bacteria,1GBQ9@1117|Cyanobacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1252131_5	1121946.AUAX01000002_gene235	1.863e-53	192.0	2B8A6@1|root,321IR@2|Bacteria,2H5MF@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1252131_0	937777.Deipe_1849	1.859e-157	501.0	COG0451@1|root,COG0451@2|Bacteria,1WM05@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	GM	PFAM NAD dependent epimerase dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
CMS1_k127_1252131_3	1463820.JOGW01000005_gene3656	3.751e-82	288.0	COG4948@1|root,COG4948@2|Bacteria,2H17U@201174|Actinobacteria	201174|Actinobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
CMS1_k127_1252131_8	760568.Desku_0139	3.375e-17	96.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
CMS1_k127_1252131_2	477974.Daud_1722	3.888e-104	352.0	COG1180@1|root,COG1180@2|Bacteria,1V170@1239|Firmicutes,24E3W@186801|Clostridia	186801|Clostridia	C	Radical SAM superfamily	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
CMS1_k127_1252131_7	1121468.AUBR01000003_gene635	2.82e-29	119.0	COG1254@1|root,COG1254@2|Bacteria,1UEN2@1239|Firmicutes,25JM5@186801|Clostridia,42HJX@68295|Thermoanaerobacterales	186801|Clostridia	C	Acylphosphatase	-	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
CMS1_k127_1252131_6	273068.TTE0993	4.623e-46	176.0	COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,24AVJ@186801|Clostridia,42FXF@68295|Thermoanaerobacterales	186801|Clostridia	C	glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
CMS1_k127_1252131_1	324602.Caur_2175	4.653e-138	459.0	2BEFV@1|root,32CHX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1252131_4	760568.Desku_2871	3.881e-62	219.0	COG1672@1|root,COG1672@2|Bacteria,1TR21@1239|Firmicutes,24ADD@186801|Clostridia,264M2@186807|Peptococcaceae	186801|Clostridia	S	ATPase domain predominantly from Archaea	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	ATPase_2,DUF234
CMS1_k127_1270164_2	926550.CLDAP_20970	5.234e-80	272.0	2BBY6@1|root,325GN@2|Bacteria,2G746@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1270164_1	375451.RD1_3768	1.499e-111	370.0	COG4782@1|root,COG4782@2|Bacteria,1MXVC@1224|Proteobacteria,2VBCR@28211|Alphaproteobacteria,2P4JA@2433|Roseobacter	28211|Alphaproteobacteria	S	Alpha/beta hydrolase of unknown function (DUF900)	-	-	-	-	-	-	-	-	-	-	-	-	DUF900
CMS1_k127_1270164_0	309801.trd_1252	1.255e-148	482.0	COG0498@1|root,COG0498@2|Bacteria,2G66Y@200795|Chloroflexi,27XPE@189775|Thermomicrobia	189775|Thermomicrobia	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS1_k127_1270164_3	309801.trd_0519	5.875e-75	256.0	COG2316@1|root,COG2316@2|Bacteria,2G6T2@200795|Chloroflexi,27Y0R@189775|Thermomicrobia	189775|Thermomicrobia	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
CMS1_k127_1270164_4	671143.DAMO_2428	6.137e-10	61.0	COG0840@1|root,COG0840@2|Bacteria	2|Bacteria	NT	transmembrane signaling receptor activity	-	-	-	ko:K03406,ko:K17763	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	4HB_MCP_1,DUF1983,DUF3365,HAMP,HATPase_c,HBM,HisKA,MASE4,MCPsignal,PAS,Protoglobin,Response_reg,STAS
CMS1_k127_127801_1	383372.Rcas_2627	4.419e-62	233.0	COG5476@1|root,COG5476@2|Bacteria,2G7N8@200795|Chloroflexi	200795|Chloroflexi	S	MlrC C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	DUF1485,MlrC_C
CMS1_k127_127801_0	1071085.KK033114_gene1551	1.915e-158	518.0	COG0146@1|root,arCOG01512@2157|Archaea,2Y8DU@28890|Euryarchaeota,23S12@183963|Halobacteria	183963|Halobacteria	E	N-methylhydantoinase B acetone carboxylase, alpha subunit	hyuB	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
CMS1_k127_127801_4	309801.trd_A0053	5.588e-07	59.0	COG1598@1|root,COG1598@2|Bacteria	2|Bacteria	N	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
CMS1_k127_127801_2	518766.Rmar_0439	3.906e-41	172.0	COG0457@1|root,COG0457@2|Bacteria,4NERG@976|Bacteroidetes,1FJBA@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Oxygen tolerance	-	-	-	-	-	-	-	-	-	-	-	-	BatD
CMS1_k127_127801_3	1894.JOER01000073_gene7545	3.08e-17	84.0	COG0664@1|root,COG0664@2|Bacteria,2IRJW@201174|Actinobacteria	201174|Actinobacteria	T	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
CMS1_k127_1279710_10	103690.17130737	4.336e-65	239.0	COG2304@1|root,COG2304@2|Bacteria,1G1AU@1117|Cyanobacteria,1HKWX@1161|Nostocales	1117|Cyanobacteria	S	PEP-CTERM family integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	VIT
CMS1_k127_1279710_3	118173.KB235914_gene3103	2.819e-84	298.0	28I5Z@1|root,2Z893@2|Bacteria,1G4B5@1117|Cyanobacteria,1H9FN@1150|Oscillatoriales	1117|Cyanobacteria	S	Transmembrane exosortase (Exosortase_EpsH)	-	-	-	-	-	-	-	-	-	-	-	-	Exosortase_EpsH
CMS1_k127_1279710_12	443906.CMM_0031	3.034e-05	49.0	COG1695@1|root,COG1695@2|Bacteria,2IQ70@201174|Actinobacteria,4FSNP@85023|Microbacteriaceae	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
CMS1_k127_1279710_11	284031.JNXD01000006_gene2831	4.962e-33	137.0	COG3620@1|root,COG3837@1|root,COG3620@2|Bacteria,COG3837@2|Bacteria,2I4X7@201174|Actinobacteria	201174|Actinobacteria	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
CMS1_k127_1279710_0	485913.Krac_9358	1.749e-235	734.0	COG0006@1|root,COG0006@2|Bacteria	2|Bacteria	E	proline dipeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Creatinase_N,Peptidase_M24
CMS1_k127_1279710_1	485913.Krac_9361	1.035e-110	364.0	COG2084@1|root,COG2084@2|Bacteria,2G8RG@200795|Chloroflexi	200795|Chloroflexi	C	PFAM 6-phosphogluconate dehydrogenase NAD-binding	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
CMS1_k127_1279710_2	1298860.AUEM01000004_gene3287	6.837e-101	344.0	COG0683@1|root,COG0683@2|Bacteria,2IEFV@201174|Actinobacteria,4FQKX@85023|Microbacteriaceae	201174|Actinobacteria	E	Periplasmic binding protein domain	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
CMS1_k127_1279710_8	543632.JOJL01000020_gene624	4.075e-66	237.0	COG0559@1|root,COG0559@2|Bacteria,2GKAR@201174|Actinobacteria,4DM3Q@85008|Micromonosporales	201174|Actinobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
CMS1_k127_1279710_6	105422.BBPM01000060_gene4262	6.799e-72	255.0	COG4177@1|root,COG4177@2|Bacteria,2I93C@201174|Actinobacteria,2NI5U@228398|Streptacidiphilus	201174|Actinobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
CMS1_k127_1279710_4	1463825.JNXC01000014_gene7683	7.414e-78	268.0	COG0411@1|root,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria,4E494@85010|Pseudonocardiales	201174|Actinobacteria	P	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
CMS1_k127_1279710_5	351607.Acel_0910	3.309e-74	256.0	COG0410@1|root,COG0410@2|Bacteria,2GKSQ@201174|Actinobacteria,4EV0C@85013|Frankiales	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
CMS1_k127_1279710_7	639283.Snov_0200	6.643e-68	243.0	COG2159@1|root,COG2159@2|Bacteria,1R5PG@1224|Proteobacteria,2U2G9@28211|Alphaproteobacteria,3F1EG@335928|Xanthobacteraceae	28211|Alphaproteobacteria	S	Amidohydrolase	-	-	4.1.1.45	ko:K03392	ko00380,ko01100,map00380,map01100	M00038	R04323	RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
CMS1_k127_1279710_9	1242864.D187_003344	2.368e-65	233.0	COG1064@1|root,COG1064@2|Bacteria,1RAY7@1224|Proteobacteria	1224|Proteobacteria	S	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_1301293_3	926569.ANT_01080	1.482e-12	68.0	COG3526@1|root,COG3526@2|Bacteria,2G7F3@200795|Chloroflexi	200795|Chloroflexi	O	Rdx family	-	-	-	ko:K07401	-	-	-	-	ko00000	-	-	-	Rdx
CMS1_k127_1301293_1	383372.Rcas_0525	1.332e-48	193.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
CMS1_k127_1301293_0	399795.CtesDRAFT_PD0178	2.802e-62	225.0	COG0346@1|root,COG0346@2|Bacteria,1R8NP@1224|Proteobacteria,2VN1R@28216|Betaproteobacteria,4AD10@80864|Comamonadaceae	28216|Betaproteobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_3
CMS1_k127_1301293_4	760568.Desku_0140	3.719e-07	61.0	COG0653@1|root,COG0653@2|Bacteria	2|Bacteria	U	protein targeting	-	-	-	ko:K09858	-	-	-	-	ko00000	-	-	-	MtrB_PioB,SEC-C
CMS1_k127_1301293_2	1142394.PSMK_08800	5.225e-15	76.0	COG5285@1|root,COG5285@2|Bacteria,2IXYK@203682|Planctomycetes	203682|Planctomycetes	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
CMS1_k127_1303350_1	926550.CLDAP_39100	3.075e-32	128.0	COG4113@1|root,COG4113@2|Bacteria	2|Bacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
CMS1_k127_1303350_0	97139.C824_01928	3.717e-36	150.0	COG0673@1|root,COG0673@2|Bacteria,1TP83@1239|Firmicutes,248XQ@186801|Clostridia,36F4R@31979|Clostridiaceae	186801|Clostridia	S	Oxidoreductase family, C-terminal alpha beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_1303350_4	1033743.CAES01000076_gene3933	5.854e-08	55.0	COG0673@1|root,COG0673@2|Bacteria,1TQ72@1239|Firmicutes,4HAGN@91061|Bacilli,26RKY@186822|Paenibacillaceae	91061|Bacilli	S	Oxidoreductase	-	-	1.1.1.361	ko:K18652	-	-	-	-	ko00000,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_1303350_2	1120950.KB892801_gene1747	2.062e-21	106.0	COG0673@1|root,COG0673@2|Bacteria,2GJNE@201174|Actinobacteria,4DQ3F@85009|Propionibacteriales	201174|Actinobacteria	GK	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C,ROK
CMS1_k127_1303350_3	926550.CLDAP_32470	1.979e-18	94.0	COG1807@1|root,COG1807@2|Bacteria,2G8DG@200795|Chloroflexi	200795|Chloroflexi	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS1_k127_1311651_2	1121904.ARBP01000022_gene3521	2.814e-40	160.0	COG1397@1|root,COG1397@2|Bacteria,4NG36@976|Bacteroidetes,47K8Y@768503|Cytophagia	976|Bacteroidetes	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
CMS1_k127_1311651_1	479434.Sthe_3412	2.043e-53	199.0	COG1032@1|root,COG1032@2|Bacteria,2G6ZI@200795|Chloroflexi	200795|Chloroflexi	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
CMS1_k127_1311651_4	342949.PNA2_1727	5.38e-28	124.0	COG0500@1|root,arCOG01791@2157|Archaea,2XZTQ@28890|Euryarchaeota,245BV@183968|Thermococci	183968|Thermococci	Q	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS1_k127_1311651_5	394503.Ccel_1632	1.366e-25	116.0	COG0765@1|root,COG0765@2|Bacteria,1TPM3@1239|Firmicutes,248UY@186801|Clostridia,36F1P@31979|Clostridiaceae	186801|Clostridia	P	ABC transporter	glnP1	-	-	ko:K02029,ko:K02030,ko:K10040	ko02010,map02010	M00228,M00236	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
CMS1_k127_1311651_3	357808.RoseRS_4003	2.005e-30	130.0	COG0765@1|root,COG0765@2|Bacteria,2G845@200795|Chloroflexi,376Y4@32061|Chloroflexia	32061|Chloroflexia	P	TIGRFAM polar amino acid ABC transporter, inner membrane subunit	-	-	-	ko:K09971	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	BPD_transp_1
CMS1_k127_1311651_0	1056512.D515_00941	2.172e-65	235.0	COG0834@1|root,COG0834@2|Bacteria,1MVT6@1224|Proteobacteria,1RMG5@1236|Gammaproteobacteria,1Y24A@135623|Vibrionales	135623|Vibrionales	ET	NMT1/THI5 like	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_3
CMS1_k127_1311651_6	649831.L083_0542	2.319e-20	93.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4D92I@85008|Micromonosporales	201174|Actinobacteria	E	Belongs to the ABC transporter superfamily	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
CMS1_k127_1313415_3	266117.Rxyl_0343	6.971e-30	122.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	2.1.1.301	ko:K21459	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_25
CMS1_k127_1313415_4	106370.Francci3_1884	3.132e-24	104.0	COG2361@1|root,COG2361@2|Bacteria,2H0TY@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
CMS1_k127_1313415_5	926550.CLDAP_34040	1.925e-18	88.0	COG1669@1|root,COG1669@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
CMS1_k127_1313415_2	1120950.KB892802_gene1417	1.593e-66	237.0	COG1173@1|root,COG1173@2|Bacteria,2GMJC@201174|Actinobacteria,4DTND@85009|Propionibacteriales	201174|Actinobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_1313415_1	926550.CLDAP_31900	5.582e-93	316.0	COG0601@1|root,COG0601@2|Bacteria,2G6RM@200795|Chloroflexi	200795|Chloroflexi	P	COGs COG0601 ABC-type dipeptide oligopeptide nickel transport systems permease components	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_1313415_0	926550.CLDAP_31890	4.304e-99	346.0	COG0747@1|root,COG0747@2|Bacteria,2G89C@200795|Chloroflexi	200795|Chloroflexi	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_1320519_5	765420.OSCT_0407	3.409e-58	207.0	COG0745@1|root,COG0745@2|Bacteria,2G6A5@200795|Chloroflexi,3752X@32061|Chloroflexia	32061|Chloroflexia	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_1320519_1	926569.ANT_02630	1.894e-109	361.0	COG0226@1|root,COG0226@2|Bacteria,2G7T2@200795|Chloroflexi	200795|Chloroflexi	P	TIGRFAM phosphate binding protein	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
CMS1_k127_1320519_4	926569.ANT_02640	5.263e-95	321.0	COG0573@1|root,COG0573@2|Bacteria,2G62J@200795|Chloroflexi	200795|Chloroflexi	P	probably responsible for the translocation of the substrate across the membrane	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
CMS1_k127_1320519_0	926569.ANT_02650	3.361e-110	364.0	COG0581@1|root,COG0581@2|Bacteria,2G6BI@200795|Chloroflexi	2|Bacteria	P	TIGRFAM phosphate ABC transporter, inner membrane subunit PstA	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
CMS1_k127_1320519_3	335543.Sfum_0702	6.672e-97	322.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,42NXP@68525|delta/epsilon subdivisions,2WK2A@28221|Deltaproteobacteria,2MRC2@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
CMS1_k127_1320519_2	373903.Hore_21550	1.023e-107	357.0	COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,247RD@186801|Clostridia,3WA6K@53433|Halanaerobiales	186801|Clostridia	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
CMS1_k127_1320519_6	926569.ANT_01750	6.877e-58	218.0	COG5002@1|root,COG5002@2|Bacteria,2G67W@200795|Chloroflexi	200795|Chloroflexi	T	PFAM ATP-binding region, ATPase domain protein	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,sCache_like
CMS1_k127_1320519_7	255470.cbdbA158	2.334e-17	81.0	COG0745@1|root,COG0745@2|Bacteria,2G6A5@200795|Chloroflexi,34D9D@301297|Dehalococcoidia	301297|Dehalococcoidia	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_1320938_8	1151126.AQYI01000007_gene2043	2.788e-19	94.0	COG0642@1|root,COG2205@2|Bacteria,2IIK0@201174|Actinobacteria	201174|Actinobacteria	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
CMS1_k127_1320938_4	1122182.KB903836_gene5006	1.504e-96	324.0	COG0745@1|root,COG0745@2|Bacteria,2H3IN@201174|Actinobacteria	201174|Actinobacteria	T	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_1320938_6	1123065.ATWL01000006_gene2187	8.088e-53	201.0	COG3173@1|root,COG3173@2|Bacteria,2I5QH@201174|Actinobacteria	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS1_k127_1320938_7	1121456.ATVA01000012_gene2811	4.517e-40	161.0	COG0615@1|root,COG0615@2|Bacteria,1N9T6@1224|Proteobacteria,42XKF@68525|delta/epsilon subdivisions,2WT6J@28221|Deltaproteobacteria,2M8UX@213115|Desulfovibrionales	28221|Deltaproteobacteria	IM	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
CMS1_k127_1320938_5	1173026.Glo7428_4407	6.609e-87	304.0	COG0510@1|root,COG0510@2|Bacteria,1G6EX@1117|Cyanobacteria	1117|Cyanobacteria	M	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS1_k127_1320938_0	1173026.Glo7428_2228	1.328e-238	752.0	COG1132@1|root,COG1132@2|Bacteria,1G1JY@1117|Cyanobacteria	1117|Cyanobacteria	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS1_k127_1320938_1	1173026.Glo7428_4405	3.794e-153	495.0	COG0438@1|root,COG0438@2|Bacteria,1G271@1117|Cyanobacteria	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
CMS1_k127_1320938_2	1173026.Glo7428_4404	1.545e-151	490.0	COG0438@1|root,COG0438@2|Bacteria,1G0ZR@1117|Cyanobacteria	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS1_k127_1320938_3	1173026.Glo7428_4403	3.951e-131	434.0	COG4671@1|root,COG4671@2|Bacteria,1G0X1@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Glycosyltransferase family 28 C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	iJN678.sll1722	Glyco_tran_28_C
CMS1_k127_1322502_2	344747.PM8797T_06967	4.465e-16	81.0	COG0673@1|root,COG0673@2|Bacteria,2J1SW@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_1322502_0	326427.Cagg_3745	4.882e-66	229.0	COG0494@1|root,COG0494@2|Bacteria	2|Bacteria	L	nUDIX hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS1_k127_1322502_1	1229172.JQFA01000004_gene1195	9.414e-41	159.0	COG3675@1|root,COG3675@2|Bacteria,1GCRE@1117|Cyanobacteria,1HF2U@1150|Oscillatoriales	1117|Cyanobacteria	I	Protein of unknown function (DUF2974)	-	-	3.1.1.3	ko:K01046	ko00561,ko01100,map00561,map01100	M00098	R02250,R02687	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko00002,ko01000	-	-	-	Lipase_3
CMS1_k127_1328575_3	357808.RoseRS_3697	8.384e-46	173.0	COG3428@1|root,COG3428@2|Bacteria	2|Bacteria	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
CMS1_k127_1328575_1	357808.RoseRS_3527	2.646e-255	794.0	COG2719@1|root,COG2719@2|Bacteria,2G83B@200795|Chloroflexi,3758M@32061|Chloroflexia	32061|Chloroflexia	S	SpoVR like protein	-	-	-	ko:K06415	-	-	-	-	ko00000	-	-	-	SpoVR
CMS1_k127_1328575_2	765420.OSCT_3035	5.359e-191	601.0	COG2718@1|root,COG2718@2|Bacteria,2G6DB@200795|Chloroflexi,375C8@32061|Chloroflexia	32061|Chloroflexia	S	Belongs to the UPF0229 family	-	-	-	ko:K09786	-	-	-	-	ko00000	-	-	-	DUF444
CMS1_k127_1328575_0	357808.RoseRS_3529	0.0	1180.0	COG2766@1|root,COG2766@2|Bacteria,2G65T@200795|Chloroflexi,3756U@32061|Chloroflexia	32061|Chloroflexia	T	PFAM PrkA serine kinase	-	-	-	ko:K07180	-	-	-	-	ko00000	-	-	-	AAA_PrkA,PrkA
CMS1_k127_1328575_5	751994.AGIG01000007_gene1276	5.105e-19	100.0	COG3023@1|root,COG3023@2|Bacteria,1RDHU@1224|Proteobacteria,1S3PG@1236|Gammaproteobacteria,1J61Z@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	COG3023 Negative regulator of beta-lactamase expression	ampD	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043170,GO:0044424,GO:0044464,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	3.5.1.28	ko:K01447,ko:K03806	-	-	R04112	RC00064,RC00141	ko00000,ko01000,ko01011	-	-	iAF1260.b0110,iB21_1397.B21_00108,iBWG_1329.BWG_0103,iEC55989_1330.EC55989_0103,iECBD_1354.ECBD_3509,iECB_1328.ECB_00109,iECDH10B_1368.ECDH10B_0090,iECDH1ME8569_1439.ECDH1ME8569_0104,iECD_1391.ECD_00109,iECIAI1_1343.ECIAI1_0107,iECO103_1326.ECO103_0110,iECO111_1330.ECO111_0111,iECO26_1355.ECO26_0112,iECSE_1348.ECSE_0110,iECW_1372.ECW_m0107,iEKO11_1354.EKO11_3806,iETEC_1333.ETEC_0106,iEcDH1_1363.EcDH1_3492,iEcE24377_1341.EcE24377A_0112,iEcHS_1320.EcHS_A0114,iEcolC_1368.EcolC_3549,iJO1366.b0110,iSFV_1184.SFV_0101,iSF_1195.SF0107,iSFxv_1172.SFxv_0113,iS_1188.S0109,iUMNK88_1353.UMNK88_108,iWFL_1372.ECW_m0107,iY75_1357.Y75_RS00560	Amidase_2
CMS1_k127_1328575_4	1396418.BATQ01000163_gene1987	1.543e-29	133.0	COG0739@1|root,COG0739@2|Bacteria,46VAI@74201|Verrucomicrobia,2IU93@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CMS1_k127_1329045_1	518766.Rmar_1790	8.177e-24	108.0	COG1228@1|root,COG1228@2|Bacteria,4NEV0@976|Bacteroidetes	976|Bacteroidetes	Q	Pfam Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
CMS1_k127_1329045_3	1121890.AUDO01000001_gene981	2.885e-06	58.0	COG1652@1|root,COG1652@2|Bacteria,4NMED@976|Bacteroidetes,1I1AU@117743|Flavobacteriia,2NWPA@237|Flavobacterium	976|Bacteroidetes	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON,LysM
CMS1_k127_1329045_2	675635.Psed_0203	1.629e-11	70.0	2DNVA@1|root,32ZBE@2|Bacteria,2GRAT@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1329045_0	765420.OSCT_2281	6.153e-71	261.0	COG2909@1|root,COG2909@2|Bacteria,2G7Q4@200795|Chloroflexi,3754G@32061|Chloroflexia	32061|Chloroflexia	K	ATP-dependent transcriptional regulator, MalT-like, LuxR family	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
CMS1_k127_1340395_3	309801.trd_0073	1.012e-07	56.0	COG2234@1|root,COG2234@2|Bacteria,2G9MK@200795|Chloroflexi,27XKJ@189775|Thermomicrobia	189775|Thermomicrobia	S	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
CMS1_k127_1340395_0	886293.Sinac_6962	1.078e-243	762.0	COG3391@1|root,COG3391@2|Bacteria,2IXYJ@203682|Planctomycetes	203682|Planctomycetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1340395_2	42256.RradSPS_2777	7.223e-15	80.0	COG4113@1|root,COG4113@2|Bacteria	2|Bacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07065	-	-	-	-	ko00000	-	-	-	PIN
CMS1_k127_1340395_4	290317.Cpha266_1381	3.758e-07	55.0	COG0864@1|root,COG0864@2|Bacteria	2|Bacteria	K	response to nickel cation	ndoAI	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K07723	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	RHH_1
CMS1_k127_1340395_5	113355.CM001775_gene188	3.861e-06	51.0	2AFHA@1|root,315HT@2|Bacteria,1G5WD@1117|Cyanobacteria	1117|Cyanobacteria	J	PFAM S23 ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
CMS1_k127_1340395_1	926569.ANT_20720	9.314e-108	358.0	COG3842@1|root,COG3842@2|Bacteria,2G5X9@200795|Chloroflexi	200795|Chloroflexi	P	PFAM ABC transporter related	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
CMS1_k127_1340805_3	926550.CLDAP_16420	2.128e-51	204.0	COG0741@1|root,COG1470@1|root,COG0741@2|Bacteria,COG1470@2|Bacteria	2|Bacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,NPCBM_assoc,Phage_HK97_TLTM,SLT
CMS1_k127_1340805_2	113355.CM001775_gene2931	1.601e-67	246.0	COG2304@1|root,COG2304@2|Bacteria,1G1BE@1117|Cyanobacteria	1117|Cyanobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	Macro,VWA
CMS1_k127_1340805_5	631362.Thi970DRAFT_00460	8.53e-14	80.0	COG0789@1|root,COG0789@2|Bacteria	2|Bacteria	K	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	MerR_1
CMS1_k127_1340805_0	1122222.AXWR01000035_gene216	0.0	1117.0	COG0058@1|root,COG0058@2|Bacteria,1WIR5@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Alpha-glucan phosphorylase	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
CMS1_k127_1340805_1	1121468.AUBR01000048_gene1644	9.649e-223	701.0	COG1053@1|root,COG1053@2|Bacteria,1TPAR@1239|Firmicutes,247SY@186801|Clostridia	186801|Clostridia	C	PFAM fumarate reductase succinate dehydrogenase flavoprotein	-	-	1.3.5.1,1.3.5.4,1.3.99.33	ko:K00239,ko:K00244,ko:K17363	ko00020,ko00190,ko00340,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00340,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164,R10330	RC00045,RC00669	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,FMN_bind,FMN_red
CMS1_k127_1340805_4	760568.Desku_1500	2.658e-26	109.0	COG1152@1|root,COG1152@2|Bacteria,1UKJG@1239|Firmicutes,25FYP@186801|Clostridia,26446@186807|Peptococcaceae	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_4,Fer4_10,Fer4_9
CMS1_k127_134239_0	926550.CLDAP_32470	3.084e-27	124.0	COG1807@1|root,COG1807@2|Bacteria,2G8DG@200795|Chloroflexi	200795|Chloroflexi	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS1_k127_134239_1	357808.RoseRS_0410	5.169e-10	70.0	COG1807@1|root,COG1807@2|Bacteria,2GBKP@200795|Chloroflexi,377PV@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase family 39	-	-	-	-	-	-	-	-	-	-	-	-	PMT
CMS1_k127_1348630_19	1499967.BAYZ01000157_gene603	7.473e-63	233.0	COG2203@1|root,COG2208@1|root,COG3829@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,COG3829@2|Bacteria	2|Bacteria	T	transcription factor binding	-	-	3.1.3.3	ko:K07315,ko:K17763	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF,GAF_2,GGDEF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,STAS
CMS1_k127_1348630_4	926569.ANT_29800	2.989e-175	559.0	COG0621@1|root,COG0621@2|Bacteria,2G5QK@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
CMS1_k127_1348630_3	1128421.JAGA01000002_gene1788	4.461e-178	570.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
CMS1_k127_1348630_5	1128421.JAGA01000002_gene1787	1.234e-164	528.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
CMS1_k127_1348630_22	357808.RoseRS_2988	2.829e-33	135.0	COG1670@1|root,COG1670@2|Bacteria,2G9BF@200795|Chloroflexi,375XR@32061|Chloroflexia	32061|Chloroflexia	J	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_3
CMS1_k127_1348630_9	1521187.JPIM01000027_gene1225	1.377e-146	483.0	COG0608@1|root,COG0608@2|Bacteria,2G5US@200795|Chloroflexi,374UZ@32061|Chloroflexia	32061|Chloroflexia	L	PFAM phosphoesterase, RecJ domain protein	-	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
CMS1_k127_1348630_15	357808.RoseRS_3920	3.514e-90	307.0	COG0223@1|root,COG0223@2|Bacteria,2G69J@200795|Chloroflexi,3759R@32061|Chloroflexia	32061|Chloroflexia	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
CMS1_k127_1348630_14	1121403.AUCV01000004_gene2011	7.821e-99	338.0	COG0477@1|root,COG2814@2|Bacteria,1QWMM@1224|Proteobacteria,42PZZ@68525|delta/epsilon subdivisions,2WJ1J@28221|Deltaproteobacteria,2MIYY@213118|Desulfobacterales	28221|Deltaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	ko:K08223	-	-	-	-	ko00000,ko02000	2.A.1.35	-	-	MFS_1
CMS1_k127_1348630_24	70601.3256916	8.835e-26	123.0	COG1874@1|root,arCOG05856@2157|Archaea,2Y2E1@28890|Euryarchaeota,243W7@183968|Thermococci	183968|Thermococci	G	Beta-galactosidase	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42
CMS1_k127_1348630_23	883112.HMPREF9707_01038	4.93e-29	121.0	COG1051@1|root,COG1051@2|Bacteria,1VAMK@1239|Firmicutes,4HKCB@91061|Bacilli	91061|Bacilli	F	Belongs to the Nudix hydrolase family	apfA	-	3.6.1.61	ko:K18445	ko00230,map00230	-	R00184	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
CMS1_k127_1348630_21	926550.CLDAP_10530	2.428e-33	145.0	COG0457@1|root,COG0823@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,2G8PZ@200795|Chloroflexi	200795|Chloroflexi	U	WD40 domain protein beta Propeller	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
CMS1_k127_1348630_11	926560.KE387027_gene366	1.226e-124	413.0	COG1680@1|root,COG1680@2|Bacteria,1WJK2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS1_k127_1348630_13	368407.Memar_1915	3.115e-112	374.0	COG0436@1|root,arCOG01133@2157|Archaea,2XU6A@28890|Euryarchaeota,2N9FK@224756|Methanomicrobia	224756|Methanomicrobia	E	PFAM Aminotransferase class I and II	-	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS1_k127_1348630_1	1128421.JAGA01000003_gene3441	4.108e-206	647.0	COG0137@1|root,COG0137@2|Bacteria,2NP01@2323|unclassified Bacteria	2|Bacteria	E	Arginosuccinate synthase	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iJN678.argG,iSB619.SA_RS04675	Arginosuc_synth
CMS1_k127_1348630_16	251221.35210750	3.71e-78	269.0	COG0483@1|root,COG0483@2|Bacteria,1G10S@1117|Cyanobacteria	1117|Cyanobacteria	G	Inositol monophosphatase	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
CMS1_k127_1348630_10	118161.KB235922_gene2311	6.839e-127	419.0	COG1819@1|root,COG1819@2|Bacteria,1G036@1117|Cyanobacteria	1117|Cyanobacteria	CG	Glycosyltransferase family 28 N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_28,UDPGT
CMS1_k127_1348630_8	926550.CLDAP_15100	2.891e-155	499.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	MA20_35850	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
CMS1_k127_1348630_28	518766.Rmar_1585	1.218e-11	76.0	COG1493@1|root,COG1493@2|Bacteria,4P7YQ@976|Bacteroidetes	976|Bacteroidetes	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1348630_2	1047013.AQSP01000098_gene2566	2.776e-181	576.0	COG0162@1|root,COG0162@2|Bacteria,2NNMR@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0030312,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
CMS1_k127_1348630_18	986075.CathTA2_1283	1.018e-65	235.0	COG0616@1|root,COG0616@2|Bacteria,1TRQW@1239|Firmicutes,4HB4R@91061|Bacilli	91061|Bacilli	OU	signal peptide peptidase SppA	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
CMS1_k127_1348630_0	357808.RoseRS_0320	4.185e-272	841.0	COG3033@1|root,COG3033@2|Bacteria,2G7YV@200795|Chloroflexi,376SB@32061|Chloroflexia	32061|Chloroflexia	E	PFAM aromatic amino acid beta-eliminating lyase threonine aldolase	tpl	-	4.1.99.2	ko:K01668	ko00350,map00350	-	R00728	RC00355,RC00364	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
CMS1_k127_1348630_30	120017.I2FNH9	3.504e-06	61.0	COG0664@1|root,KOG1113@2759|Eukaryota,38GS1@33154|Opisthokonta,3NU9Z@4751|Fungi,3UZXM@5204|Basidiomycota,3N0FT@452284|Ustilaginomycotina	4751|Fungi	T	camp-dependent protein kinase	PKAR	GO:0000003,GO:0000228,GO:0000785,GO:0000790,GO:0001932,GO:0001933,GO:0002831,GO:0002832,GO:0003674,GO:0004857,GO:0004860,GO:0004862,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0005886,GO:0006469,GO:0006950,GO:0006979,GO:0007154,GO:0008104,GO:0008150,GO:0008603,GO:0009266,GO:0009267,GO:0009405,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009653,GO:0009892,GO:0009966,GO:0009968,GO:0009987,GO:0009991,GO:0010563,GO:0010570,GO:0010605,GO:0010639,GO:0010646,GO:0010648,GO:0016020,GO:0019207,GO:0019210,GO:0019220,GO:0019222,GO:0019887,GO:0019954,GO:0022603,GO:0023051,GO:0023057,GO:0030154,GO:0030234,GO:0030291,GO:0030435,GO:0030436,GO:0030447,GO:0030448,GO:0031279,GO:0031281,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0031667,GO:0031668,GO:0031669,GO:0031974,GO:0031981,GO:0032101,GO:0032102,GO:0032104,GO:0032105,GO:0032107,GO:0032108,GO:0032268,GO:0032269,GO:0032502,GO:0033036,GO:0033043,GO:0033554,GO:0033673,GO:0034305,GO:0034599,GO:0034605,GO:0034613,GO:0036170,GO:0036180,GO:0040007,GO:0040008,GO:0042173,GO:0042221,GO:0042325,GO:0042326,GO:0042594,GO:0043085,GO:0043086,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043549,GO:0043934,GO:0043936,GO:0043937,GO:0043938,GO:0043943,GO:0043945,GO:0044092,GO:0044093,GO:0044182,GO:0044419,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044454,GO:0044464,GO:0045595,GO:0045597,GO:0045761,GO:0045762,GO:0045859,GO:0045881,GO:0045926,GO:0045936,GO:0046578,GO:0046580,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048646,GO:0048856,GO:0048869,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051056,GO:0051058,GO:0051094,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051174,GO:0051179,GO:0051246,GO:0051248,GO:0051338,GO:0051339,GO:0051348,GO:0051349,GO:0051641,GO:0051704,GO:0051716,GO:0051783,GO:0051784,GO:0060255,GO:0060258,GO:0065007,GO:0065009,GO:0070013,GO:0070727,GO:0070887,GO:0071496,GO:0071900,GO:0071901,GO:0071944,GO:0080090,GO:0080134,GO:0097271,GO:0098772,GO:1900428,GO:1900429,GO:1900434,GO:1900435,GO:1900443,GO:1900444,GO:1902531,GO:1902532,GO:1903664,GO:1903666	-	ko:K04739	ko04910,map04910	-	-	-	ko00000,ko00001	-	-	-	RIIa,cNMP_binding
CMS1_k127_1348630_25	65393.PCC7424_4437	3.952e-18	101.0	COG5635@1|root,COG5635@2|Bacteria,1G192@1117|Cyanobacteria,3KHKT@43988|Cyanothece	1117|Cyanobacteria	T	PFAM NACHT nucleoside triphosphatase	-	-	-	-	-	-	-	-	-	-	-	-	NACHT
CMS1_k127_1348630_29	755731.Clo1100_1665	5.843e-11	77.0	COG0457@1|root,COG0457@2|Bacteria,1UYZH@1239|Firmicutes,24BU9@186801|Clostridia,36NTK@31979|Clostridiaceae	186801|Clostridia	S	Anaphase-promoting complex, cyclosome, subunit 3	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_8
CMS1_k127_1348630_26	588726.J7RPN6	7.374e-16	93.0	COG0664@1|root,KOG1113@2759|Eukaryota,38GS1@33154|Opisthokonta,3NU9Z@4751|Fungi,3QKI5@4890|Ascomycota,3RSCY@4891|Saccharomycetes,3RYS1@4893|Saccharomycetaceae	4751|Fungi	T	cAMP-dependent protein kinase regulatory subunit	PKAR	GO:0000003,GO:0000166,GO:0000228,GO:0000785,GO:0000790,GO:0001932,GO:0001933,GO:0002831,GO:0002832,GO:0003674,GO:0004857,GO:0004860,GO:0004862,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0005886,GO:0005952,GO:0006469,GO:0006950,GO:0006979,GO:0007154,GO:0008104,GO:0008150,GO:0008277,GO:0008603,GO:0009266,GO:0009267,GO:0009405,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009653,GO:0009892,GO:0009966,GO:0009968,GO:0009987,GO:0009991,GO:0010563,GO:0010570,GO:0010605,GO:0010639,GO:0010646,GO:0010648,GO:0016020,GO:0017076,GO:0019207,GO:0019210,GO:0019220,GO:0019222,GO:0019887,GO:0019954,GO:0022603,GO:0023051,GO:0023057,GO:0030154,GO:0030234,GO:0030291,GO:0030435,GO:0030436,GO:0030447,GO:0030448,GO:0030551,GO:0030552,GO:0030554,GO:0031279,GO:0031281,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0031667,GO:0031668,GO:0031669,GO:0031974,GO:0031981,GO:0032101,GO:0032102,GO:0032104,GO:0032105,GO:0032107,GO:0032108,GO:0032268,GO:0032269,GO:0032386,GO:0032388,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032879,GO:0032880,GO:0032991,GO:0033036,GO:0033043,GO:0033157,GO:0033554,GO:0033673,GO:0034305,GO:0034599,GO:0034605,GO:0034613,GO:0036094,GO:0036170,GO:0036180,GO:0040007,GO:0040008,GO:0042173,GO:0042221,GO:0042325,GO:0042326,GO:0042594,GO:0043085,GO:0043086,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043549,GO:0043934,GO:0043936,GO:0043937,GO:0043938,GO:0043943,GO:0043945,GO:0043949,GO:0043951,GO:0044092,GO:0044093,GO:0044182,GO:0044419,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044454,GO:0044464,GO:0045595,GO:0045597,GO:0045744,GO:0045761,GO:0045762,GO:0045786,GO:0045859,GO:0045881,GO:0045926,GO:0045936,GO:0046578,GO:0046580,GO:0046822,GO:0046824,GO:0046825,GO:0046827,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048646,GO:0048856,GO:0048869,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051049,GO:0051050,GO:0051056,GO:0051058,GO:0051094,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051174,GO:0051179,GO:0051222,GO:0051223,GO:0051246,GO:0051248,GO:0051338,GO:0051339,GO:0051348,GO:0051349,GO:0051445,GO:0051447,GO:0051641,GO:0051704,GO:0051716,GO:0051726,GO:0051783,GO:0051784,GO:0060255,GO:0060258,GO:0060341,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070201,GO:0070727,GO:0070887,GO:0071496,GO:0071900,GO:0071901,GO:0071944,GO:0080090,GO:0080134,GO:0090087,GO:0090316,GO:0097159,GO:0097271,GO:0097367,GO:0098772,GO:0106070,GO:0106072,GO:0110033,GO:0110034,GO:1900428,GO:1900429,GO:1900434,GO:1900435,GO:1900443,GO:1900444,GO:1901265,GO:1901363,GO:1902531,GO:1902532,GO:1902659,GO:1902660,GO:1903664,GO:1903666,GO:1903827,GO:1903829,GO:1904951,GO:2000241,GO:2000242,GO:2000479,GO:2000480	-	ko:K04739	ko04910,map04910	-	-	-	ko00000,ko00001	-	-	-	RIIa,cNMP_binding
CMS1_k127_1348630_27	316274.Haur_1610	1.122e-11	79.0	COG2114@1|root,COG2203@1|root,COG2114@2|Bacteria,COG2203@2|Bacteria,2G6X8@200795|Chloroflexi	200795|Chloroflexi	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
CMS1_k127_1348630_7	926569.ANT_13340	4.382e-156	527.0	COG1472@1|root,COG1472@2|Bacteria,2G7PD@200795|Chloroflexi	200795|Chloroflexi	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
CMS1_k127_1348630_6	926550.CLDAP_26250	4.264e-156	499.0	COG0524@1|root,COG0524@2|Bacteria,2G5XM@200795|Chloroflexi	200795|Chloroflexi	G	pfkB family carbohydrate kinase	-	-	2.7.1.92	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R05661	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
CMS1_k127_1348630_20	309807.SRU_2151	2.629e-42	160.0	2DKY3@1|root,32UFX@2|Bacteria	2|Bacteria	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
CMS1_k127_1348630_12	926550.CLDAP_26260	5.648e-120	392.0	COG3718@1|root,COG3718@2|Bacteria,2G708@200795|Chloroflexi	200795|Chloroflexi	G	PFAM Myo-inositol catabolism IolB domain protein	-	-	5.3.1.30	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R08503	RC00541	ko00000,ko00001,ko01000	-	-	-	KduI
CMS1_k127_1348630_17	1499967.BAYZ01000103_gene3718	2.475e-75	256.0	COG1028@1|root,COG1028@2|Bacteria,2NQZI@2323|unclassified Bacteria	2|Bacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS1_k127_1372350_2	1121377.KB906404_gene2877	1.453e-37	154.0	COG0515@1|root,COG0515@2|Bacteria,1WIDK@1297|Deinococcus-Thermus	1121377.KB906404_gene2877|-	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1372350_0	1128421.JAGA01000003_gene3678	4.333e-54	203.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2NQCZ@2323|unclassified Bacteria	2|Bacteria	K	NB-ARC domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_22,BTAD,NB-ARC,TPR_10,TPR_12,TPR_8,Trans_reg_C
CMS1_k127_1372350_3	765420.OSCT_1927	6.141e-31	131.0	COG2968@1|root,COG2968@2|Bacteria,2G6UC@200795|Chloroflexi,377CQ@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function (DUF541)	-	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
CMS1_k127_1372350_4	1321778.HMPREF1982_01578	8.877e-08	64.0	2ERNT@1|root,33J87@2|Bacteria,1VMAP@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1372350_1	1128421.JAGA01000001_gene2454	1.656e-45	173.0	COG0745@1|root,COG0745@2|Bacteria,2NQZN@2323|unclassified Bacteria	2|Bacteria	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_1383104_3	935948.KE386495_gene1151	4.669e-15	87.0	COG0673@1|root,COG0673@2|Bacteria,1TQ72@1239|Firmicutes,24G9W@186801|Clostridia,42HNI@68295|Thermoanaerobacterales	186801|Clostridia	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_1383104_4	1123276.KB893270_gene4719	2.061e-07	59.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	dad	-	1.13.11.41,1.13.11.50	ko:K05913,ko:K20148	ko00363,ko01120,map00363,map01120	-	R01305	RC00415,RC01565	ko00000,ko00001,ko01000	-	-	-	Cupin_2,Cupin_7
CMS1_k127_1383104_2	926550.CLDAP_29640	7.101e-37	163.0	COG3664@1|root,COG3664@2|Bacteria,2GBKT@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycoside hydrolase family 39	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1383104_0	926550.CLDAP_17040	7.438e-128	456.0	COG5276@1|root,COG5276@2|Bacteria,2G8F2@200795|Chloroflexi	200795|Chloroflexi	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
CMS1_k127_1383104_5	1120917.AQXM01000061_gene1840	5.258e-05	49.0	COG3435@1|root,COG3435@2|Bacteria,2GKAE@201174|Actinobacteria,1W9E4@1268|Micrococcaceae	201174|Actinobacteria	Q	Cupin domain	-	-	1.13.11.4	ko:K00450	ko00350,ko01100,ko01120,map00350,map01100,map01120	-	R02656	RC00764	ko00000,ko00001,ko01000	-	-	-	AraC_binding,Cupin_2
CMS1_k127_1383104_1	383372.Rcas_2446	1.073e-105	348.0	2CC7E@1|root,2Z7WG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_138692_0	1128421.JAGA01000002_gene1555	0.0	1490.0	COG0067@1|root,COG0069@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,2NP08@2323|unclassified Bacteria	2|Bacteria	E	Glutamate synthase central domain	gltB	GO:0003674,GO:0003824,GO:0004355,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045181,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	iBWG_1329.BWG_2914,iECDH10B_1368.ECDH10B_3387,iECDH1ME8569_1439.EcDH1_0495,iEcDH1_1363.EcDH1_0495,iPC815.YPO3557	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
CMS1_k127_138762_7	1120950.KB892777_gene762	8.285e-08	55.0	COG1063@1|root,COG1063@2|Bacteria,2GKC7@201174|Actinobacteria,4DR90@85009|Propionibacteriales	201174|Actinobacteria	C	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.303,1.1.1.4	ko:K00004	ko00650,map00650	-	R02855,R02946,R10504	RC00205,RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_138762_3	639030.JHVA01000001_gene3231	6.504e-109	365.0	COG4948@1|root,COG4948@2|Bacteria,3Y2UE@57723|Acidobacteria,2JKF5@204432|Acidobacteriia	204432|Acidobacteriia	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
CMS1_k127_138762_4	935836.JAEL01000029_gene3574	1.509e-57	205.0	COG0075@1|root,COG3916@1|root,COG0075@2|Bacteria,COG3916@2|Bacteria,1TR3I@1239|Firmicutes,4HA6W@91061|Bacilli,1ZAT2@1386|Bacillus	91061|Bacilli	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_5,Acetyltransf_9,Aminotran_5
CMS1_k127_138762_6	203119.Cthe_0236	1.314e-34	143.0	COG1453@1|root,COG1453@2|Bacteria,1TQ5N@1239|Firmicutes,24BGZ@186801|Clostridia,3WJAE@541000|Ruminococcaceae	186801|Clostridia	C	PFAM aldo keto reductase	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17,Fer4_9
CMS1_k127_138762_0	477228.YO5_07923	1.001e-191	606.0	COG3930@1|root,COG3930@2|Bacteria,1PYFH@1224|Proteobacteria,1RP1J@1236|Gammaproteobacteria,1Z18N@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	S	protein conserved in bacteria	IV02_27630	-	-	-	-	-	-	-	-	-	-	-	DUF1704
CMS1_k127_138762_5	324057.Pjdr2_5125	3.341e-57	213.0	COG1063@1|root,COG1063@2|Bacteria,1VCXY@1239|Firmicutes,4HUDN@91061|Bacilli,2766S@186822|Paenibacillaceae	91061|Bacilli	E	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N
CMS1_k127_138762_2	1254432.SCE1572_09950	9.227e-110	371.0	COG4826@1|root,COG4826@2|Bacteria,1REGX@1224|Proteobacteria,42T9N@68525|delta/epsilon subdivisions,2WPDB@28221|Deltaproteobacteria,2YV97@29|Myxococcales	28221|Deltaproteobacteria	O	Belongs to the serpin family	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
CMS1_k127_138762_1	926550.CLDAP_27180	2.847e-137	438.0	COG4284@1|root,COG4284@2|Bacteria	2|Bacteria	G	Utp--glucose-1-phosphate uridylyltransferase	-	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPGP
CMS1_k127_138915_4	1095769.CAHF01000022_gene194	4.35e-10	66.0	COG1752@1|root,COG1752@2|Bacteria,1MUI6@1224|Proteobacteria,2WDK7@28216|Betaproteobacteria,4786Z@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
CMS1_k127_138915_0	1303518.CCALI_01746	8.246e-152	491.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_138915_2	765420.OSCT_1574	9.472e-71	264.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
CMS1_k127_138915_3	449447.MAE_57760	6.96e-19	93.0	COG2405@1|root,COG2405@2|Bacteria,1GETK@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_138915_5	69014.TK0213	9.527e-05	48.0	COG2886@1|root,arCOG00722@2157|Archaea,2Y0J3@28890|Euryarchaeota,244HA@183968|Thermococci	183968|Thermococci	S	Uncharacterised protein family (UPF0175)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0175
CMS1_k127_138915_1	1173023.KE650771_gene4438	5.17e-112	374.0	COG0465@1|root,COG0465@2|Bacteria,1G46Q@1117|Cyanobacteria	1117|Cyanobacteria	O	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
CMS1_k127_1405600_5	926550.CLDAP_25010	6.446e-43	160.0	COG0365@1|root,COG0365@2|Bacteria,2G830@200795|Chloroflexi	200795|Chloroflexi	I	Acetyl-coenzyme A synthetase N-terminus	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
CMS1_k127_1405600_0	404380.Gbem_1886	1.299e-120	393.0	COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,42MXZ@68525|delta/epsilon subdivisions,2WJWG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the arginase family	-	-	3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
CMS1_k127_1405600_2	66874.JOFS01000001_gene1137	1.746e-46	186.0	COG1653@1|root,COG1653@2|Bacteria,2I9UX@201174|Actinobacteria	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
CMS1_k127_1405600_1	1280390.CBQR020000141_gene3489	3.483e-73	258.0	COG1175@1|root,COG1175@2|Bacteria,1TPTZ@1239|Firmicutes,4HB63@91061|Bacilli,26S91@186822|Paenibacillaceae	91061|Bacilli	G	ABC transporter permease	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_1405600_4	266940.Krad_2543	6.596e-45	169.0	COG0395@1|root,COG0395@2|Bacteria,2I8US@201174|Actinobacteria	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
CMS1_k127_1409638_12	926550.CLDAP_22280	2.795e-42	157.0	COG3019@1|root,COG3019@2|Bacteria	2|Bacteria	S	metal-binding protein	copG	-	-	-	-	-	-	-	-	-	-	-	DUF411
CMS1_k127_1409638_20	439375.Oant_0226	3.206e-06	57.0	COG1974@1|root,COG1974@2|Bacteria	2|Bacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
CMS1_k127_1409638_4	596151.DesfrDRAFT_2592	7.419e-71	247.0	COG1208@1|root,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,42MX5@68525|delta/epsilon subdivisions,2X5IA@28221|Deltaproteobacteria,2MGRF@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,NTP_transferase
CMS1_k127_1409638_0	867845.KI911784_gene2882	5.728e-134	443.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,2G67F@200795|Chloroflexi,3769D@32061|Chloroflexia	32061|Chloroflexia	M	PFAM sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
CMS1_k127_1409638_19	243231.GSU0549	2.815e-06	55.0	COG2227@1|root,COG2227@2|Bacteria,1QXN3@1224|Proteobacteria,43C46@68525|delta/epsilon subdivisions,2X7EM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS1_k127_1409638_18	1254432.SCE1572_34345	9.634e-07	57.0	COG0457@1|root,COG1672@1|root,COG0457@2|Bacteria,COG1672@2|Bacteria,1NB06@1224|Proteobacteria,43AS1@68525|delta/epsilon subdivisions,2X665@28221|Deltaproteobacteria,2YYB2@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,TPR_12,TPR_8
CMS1_k127_1409638_1	1121377.KB906402_gene3232	1.093e-117	424.0	COG0457@1|root,COG3899@1|root,COG0457@2|Bacteria,COG3899@2|Bacteria	2|Bacteria	T	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,Trans_reg_C
CMS1_k127_1409638_8	1121422.AUMW01000002_gene2258	1.954e-56	227.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,26066@186807|Peptococcaceae	186801|Clostridia	KLT	PFAM Protein kinase domain	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
CMS1_k127_1409638_7	1128421.JAGA01000003_gene3678	6.366e-60	239.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2NQCZ@2323|unclassified Bacteria	2|Bacteria	K	NB-ARC domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_22,BTAD,NB-ARC,TPR_10,TPR_12,TPR_8,Trans_reg_C
CMS1_k127_1409638_17	867845.KI911784_gene2568	4.086e-08	60.0	COG2319@1|root,COG2319@2|Bacteria	2|Bacteria	S	anaphase-promoting complex binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF4912,PBP_like_2,TPR_8,WD40
CMS1_k127_1409638_11	504728.K649_10010	8.762e-45	167.0	COG0607@1|root,COG0607@2|Bacteria,1WMYW@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CMS1_k127_1409638_16	1120934.KB894405_gene5429	1.595e-11	72.0	COG1765@1|root,COG1765@2|Bacteria,2IE9R@201174|Actinobacteria,4EEZJ@85010|Pseudonocardiales	201174|Actinobacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
CMS1_k127_1409638_3	56780.SYN_01137	1.239e-88	310.0	COG3866@1|root,COG3866@2|Bacteria,1MUT3@1224|Proteobacteria,42S47@68525|delta/epsilon subdivisions,2WND1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Pectate lyase	-	-	-	-	-	-	-	-	-	-	-	-	Pec_lyase_C
CMS1_k127_1409638_15	1009370.ALO_08440	3.25e-17	93.0	COG1357@1|root,COG1357@2|Bacteria	2|Bacteria	S	protein homooligomerization	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
CMS1_k127_1409638_13	1202768.JROF01000013_gene870	8.798e-42	175.0	COG4177@1|root,arCOG01274@2157|Archaea,2XWFD@28890|Euryarchaeota,23SM0@183963|Halobacteria	183963|Halobacteria	E	COG4177 ABC-type branched-chain amino acid transport system, permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
CMS1_k127_1409638_9	1227487.C474_16634	3.954e-53	198.0	COG0559@1|root,arCOG01270@2157|Archaea,2XW7A@28890|Euryarchaeota,23UMU@183963|Halobacteria	183963|Halobacteria	E	COG0559 Branched-chain amino acid ABC-type transport system, permease components	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
CMS1_k127_1409638_5	78245.Xaut_1566	7.106e-65	229.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2TSA6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	branched-chain amino acid	MA20_14125	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
CMS1_k127_1409638_6	1382356.JQMP01000003_gene2483	5.42e-60	215.0	COG0411@1|root,COG0411@2|Bacteria	2|Bacteria	E	ABC transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
CMS1_k127_1409638_10	1227487.C474_16639	2.563e-45	181.0	COG0683@1|root,arCOG01020@2157|Archaea,2XUWA@28890|Euryarchaeota,23TUR@183963|Halobacteria	183963|Halobacteria	E	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
CMS1_k127_1409638_21	1174528.JH992887_gene6187	0.0001742	47.0	COG4644@1|root,COG4644@2|Bacteria,1G47Y@1117|Cyanobacteria	1117|Cyanobacteria	L	Domain of unknown function (DUF4158)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4158
CMS1_k127_1409638_14	927677.ALVU02000007_gene4724	1.637e-28	115.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
CMS1_k127_1409638_2	927677.ALVU02000004_gene4738	3.141e-102	374.0	COG3903@1|root,COG3903@2|Bacteria	2|Bacteria	K	ADP binding	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,DUF4062,NB-ARC,TPR_12
CMS1_k127_1410458_0	926550.CLDAP_16850	1.689e-239	754.0	COG0747@1|root,COG0747@2|Bacteria,2G5SA@200795|Chloroflexi	200795|Chloroflexi	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_1410458_1	1381123.AYOD01000001_gene1120	3.521e-148	475.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TSF3@28211|Alphaproteobacteria,43NDR@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	appB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_1410458_4	926550.CLDAP_16870	1.137e-113	374.0	COG1173@1|root,COG1173@2|Bacteria,2G63I@200795|Chloroflexi	200795|Chloroflexi	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
CMS1_k127_1410458_6	316274.Haur_4061	4.077e-55	220.0	COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,2G8PA@200795|Chloroflexi,376UG@32061|Chloroflexia	32061|Chloroflexia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
CMS1_k127_1410458_8	926569.ANT_08940	3.66e-08	63.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
CMS1_k127_1410458_9	1330700.JQNC01000003_gene722	1.125e-06	62.0	COG1470@1|root,COG4719@1|root,COG1470@2|Bacteria,COG4719@2|Bacteria,1WJNZ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
CMS1_k127_1410458_7	357808.RoseRS_2295	2.375e-43	181.0	COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,2GAAK@200795|Chloroflexi,374SE@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS
CMS1_k127_1410458_2	1128421.JAGA01000002_gene1037	4.946e-146	475.0	COG0486@1|root,COG0486@2|Bacteria,2NNS4@2323|unclassified Bacteria	2|Bacteria	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
CMS1_k127_1410458_5	324602.Caur_1591	9.972e-97	330.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	ydeG	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
CMS1_k127_1410458_3	357808.RoseRS_2969	8.194e-142	456.0	COG0183@1|root,COG0183@2|Bacteria,2G5YW@200795|Chloroflexi,3755G@32061|Chloroflexia	32061|Chloroflexia	I	Belongs to the thiolase family	-	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
CMS1_k127_141366_1	1089551.KE386572_gene3912	1.062e-50	195.0	COG0477@1|root,COG2814@2|Bacteria,1P3S4@1224|Proteobacteria,2TVAQ@28211|Alphaproteobacteria,4BRZV@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
CMS1_k127_141366_0	1424334.W822_02615	2.328e-130	426.0	COG4948@1|root,COG4948@2|Bacteria,1MURK@1224|Proteobacteria,2W9AM@28216|Betaproteobacteria,3T71C@506|Alcaligenaceae	28216|Betaproteobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	4.2.1.6	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R03033	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
CMS1_k127_141840_6	309801.trd_1129	1.132e-29	120.0	COG3836@1|root,COG3836@2|Bacteria,2GA3S@200795|Chloroflexi,27Z2Q@189775|Thermomicrobia	189775|Thermomicrobia	G	HpcH/HpaI aldolase/citrate lyase family	-	-	4.1.2.52	ko:K02510	ko00350,ko01120,map00350,map01120	-	R01645,R01647	RC00307,RC00572,RC00574,RC03057	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
CMS1_k127_141840_1	1267535.KB906767_gene510	3.758e-111	368.0	COG1312@1|root,COG1312@2|Bacteria	2|Bacteria	G	mannonate dehydratase activity	uxuA	-	4.2.1.8	ko:K01686	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	UxuA
CMS1_k127_141840_5	344747.PM8797T_24436	1.454e-69	248.0	COG4948@1|root,COG4948@2|Bacteria,2J32H@203682|Planctomycetes	203682|Planctomycetes	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
CMS1_k127_141840_3	926550.CLDAP_30800	6.329e-86	294.0	COG1052@1|root,COG1052@2|Bacteria,2G7VK@200795|Chloroflexi	200795|Chloroflexi	C	PFAM D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
CMS1_k127_141840_4	1463825.JNXC01000031_gene1581	3.149e-82	284.0	COG2055@1|root,COG2055@2|Bacteria,2GN93@201174|Actinobacteria,4E5WZ@85010|Pseudonocardiales	201174|Actinobacteria	C	Malate/L-lactate dehydrogenase	-	-	-	ko:K13574	-	-	-	-	ko00000,ko01000	-	-	-	Ldh_2
CMS1_k127_141840_2	1380386.JIAW01000032_gene3450	9.113e-109	361.0	COG0111@1|root,COG0111@2|Bacteria,2GJGA@201174|Actinobacteria,2333T@1762|Mycobacteriaceae	201174|Actinobacteria	E	D-isomer specific 2-hydroxyacid dehydrogenase	pdxB	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
CMS1_k127_141840_0	1347086.CCBA010000011_gene1651	7.211e-144	463.0	COG0673@1|root,COG0673@2|Bacteria,1USVA@1239|Firmicutes,4HDVM@91061|Bacilli,1ZQBZ@1386|Bacillus	91061|Bacilli	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_141840_7	1122135.KB893146_gene1702	4.225e-21	105.0	COG0697@1|root,COG0697@2|Bacteria,1MZQM@1224|Proteobacteria,2TUPG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS1_k127_1424412_3	309807.SRU_2576	2.613e-37	146.0	COG2843@1|root,COG2843@2|Bacteria,4NRD6@976|Bacteroidetes	976|Bacteroidetes	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	-	-	-	-	-	-	-	-	-	PGA_cap
CMS1_k127_1424412_0	1089551.KE386572_gene568	2.183e-153	499.0	COG3119@1|root,COG3119@2|Bacteria,1MV0B@1224|Proteobacteria,2U33R@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Sulfatase	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
CMS1_k127_1424412_2	102129.Lepto7375DRAFT_2545	6.952e-42	158.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	2.3.1.82	ko:K18815	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	Acetyltransf_1,Acetyltransf_10
CMS1_k127_1424412_1	1122927.KB895416_gene3403	1.561e-142	458.0	COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,4H9YT@91061|Bacilli,26S4T@186822|Paenibacillaceae	91061|Bacilli	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
CMS1_k127_143311_4	1123023.JIAI01000001_gene7159	1.715e-17	83.0	COG2141@1|root,COG2141@2|Bacteria,2GIY3@201174|Actinobacteria,4DXE3@85010|Pseudonocardiales	201174|Actinobacteria	C	PFAM Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS1_k127_143311_2	1122179.KB890447_gene158	1.065e-45	169.0	COG0251@1|root,COG0667@1|root,COG0251@2|Bacteria,COG0667@2|Bacteria,4NPT2@976|Bacteroidetes,1IYB6@117747|Sphingobacteriia	976|Bacteroidetes	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red,Ribonuc_L-PSP
CMS1_k127_143311_3	65393.PCC7424_1987	5.499e-20	98.0	COG0457@1|root,COG0484@1|root,COG0457@2|Bacteria,COG0484@2|Bacteria,1GITV@1117|Cyanobacteria,3KK84@43988|Cyanothece	1117|Cyanobacteria	O	heat shock protein DnaJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
CMS1_k127_143311_1	1125863.JAFN01000001_gene2762	1.324e-63	224.0	COG0235@1|root,COG0235@2|Bacteria,1N84G@1224|Proteobacteria,42RVW@68525|delta/epsilon subdivisions,2WSI5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM Class II aldolase	-	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
CMS1_k127_143311_0	370438.PTH_0921	1.348e-196	630.0	COG2414@1|root,COG2414@2|Bacteria,1TPT9@1239|Firmicutes,2481Q@186801|Clostridia,260S3@186807|Peptococcaceae	186801|Clostridia	C	Aldehyde ferredoxin oxidoreductase	aor	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS09915	AFOR_C,AFOR_N
CMS1_k127_143311_5	292459.STH2887	5.388e-15	78.0	COG1977@1|root,COG1977@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	cysO	GO:0000096,GO:0000097,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.7.7.1,2.7.7.80,2.8.1.11	ko:K00366,ko:K03636,ko:K21029,ko:K21147	ko00910,ko01120,ko04122,map00910,map01120,map04122	M00531	R00790,R07459,R07461	RC00043,RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiS
CMS1_k127_143820_4	255470.cbdbA1519	1.833e-13	76.0	2DMIY@1|root,32RWI@2|Bacteria,2G7AX@200795|Chloroflexi	200795|Chloroflexi	S	CRISPR_assoc	-	-	-	ko:K19126	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_assoc
CMS1_k127_143820_2	357808.RoseRS_0647	2.024e-50	188.0	2DBXF@1|root,2ZBPB@2|Bacteria,2G74C@200795|Chloroflexi	200795|Chloroflexi	S	CRISPR-associated protein (Cas_Cas5)	-	-	-	ko:K19125	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Cas5d
CMS1_k127_143820_0	357808.RoseRS_0648	3.451e-100	339.0	COG1857@1|root,COG1857@2|Bacteria,2G6KI@200795|Chloroflexi	200795|Chloroflexi	L	CT1975-like protein	-	-	-	ko:K19124	-	-	-	-	ko00000,ko02048	-	-	-	Cas_CT1975
CMS1_k127_143820_3	357808.RoseRS_0649	2.327e-36	143.0	2DN3X@1|root,32VDU@2|Bacteria,2G7HD@200795|Chloroflexi	200795|Chloroflexi	S	CRISPR-associated protein Cse2 (CRISPR_cse2)	-	-	-	ko:K19046	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_Cse2
CMS1_k127_143820_1	357808.RoseRS_0650	1.277e-57	212.0	COG1203@1|root,COG1203@2|Bacteria,2G710@200795|Chloroflexi	200795|Chloroflexi	L	CRISPR-associated protein Cse1 (CRISPR_cse1)	-	-	-	ko:K19123	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_Cse1
CMS1_k127_149786_4	926550.CLDAP_09490	2.545e-47	175.0	COG2313@1|root,COG2313@2|Bacteria,2G5KC@200795|Chloroflexi	200795|Chloroflexi	Q	Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway	psuG	-	4.2.1.70	ko:K16329	ko00240,map00240	-	R01055	RC00432,RC00433	ko00000,ko00001,ko01000	-	-	-	Indigoidine_A
CMS1_k127_149786_3	926550.CLDAP_30130	7.177e-53	191.0	2BX7X@1|root,336E6@2|Bacteria,2G9KF@200795|Chloroflexi	200795|Chloroflexi	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_149786_0	479434.Sthe_1657	4.924e-101	338.0	COG0648@1|root,COG0648@2|Bacteria,2G5XZ@200795|Chloroflexi,27XEG@189775|Thermomicrobia	189775|Thermomicrobia	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
CMS1_k127_149786_1	91464.S7335_1803	2.194e-96	336.0	COG2508@1|root,COG2508@2|Bacteria	2|Bacteria	QT	PucR C-terminal helix-turn-helix domain	-	-	-	ko:K09684	-	-	-	-	ko00000,ko03000	-	-	-	HTH_30,PucR
CMS1_k127_149786_2	1117319.PSPO_14244	3.791e-78	269.0	COG3324@1|root,COG3324@2|Bacteria,1R81W@1224|Proteobacteria,1RYXR@1236|Gammaproteobacteria,2Q1G4@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	enzyme related to lactoylglutathione lyase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
CMS1_k127_1500065_2	316274.Haur_0974	4.027e-63	220.0	COG1028@1|root,COG1028@2|Bacteria,2G8DK@200795|Chloroflexi,3776U@32061|Chloroflexia	32061|Chloroflexia	IQ	short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS1_k127_1500065_1	1123508.JH636440_gene2923	5.564e-138	442.0	COG0388@1|root,COG0388@2|Bacteria,2J2IE@203682|Planctomycetes	203682|Planctomycetes	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
CMS1_k127_1500065_0	649638.Trad_1384	2.341e-146	483.0	COG2041@1|root,COG2041@2|Bacteria,1WI25@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM Mo-co oxidoreductase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Mo-co_dimer,Oxidored_molyb
CMS1_k127_1500065_5	1122915.AUGY01000014_gene2750	1.562e-07	61.0	2E6HR@1|root,33150@2|Bacteria,1VF6G@1239|Firmicutes,4IR8Y@91061|Bacilli	91061|Bacilli	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
CMS1_k127_1500065_3	32057.KB217478_gene3690	1.512e-41	156.0	COG0454@1|root,COG0456@2|Bacteria,1GDTV@1117|Cyanobacteria	1117|Cyanobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS1_k127_1500065_6	660470.Theba_2258	7.041e-06	56.0	2EUJV@1|root,33N1T@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1500065_4	383372.Rcas_0428	2.371e-41	162.0	2E1HA@1|root,32WVF@2|Bacteria,2G8UA@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1501971_0	309801.trd_1512	0.0	1041.0	COG0525@1|root,COG0525@2|Bacteria,2G5VS@200795|Chloroflexi,27Y20@189775|Thermomicrobia	189775|Thermomicrobia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
CMS1_k127_1501971_1	485913.Krac_10258	4.059e-267	846.0	COG0525@1|root,COG0525@2|Bacteria,2G5VS@200795|Chloroflexi	2|Bacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
CMS1_k127_1501971_3	926569.ANT_19700	1.27e-40	157.0	COG1238@1|root,COG1238@2|Bacteria,2G932@200795|Chloroflexi	200795|Chloroflexi	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
CMS1_k127_1501971_2	525904.Tter_0335	3.44e-150	480.0	COG1013@1|root,COG1013@2|Bacteria,2NPAM@2323|unclassified Bacteria	2|Bacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
CMS1_k127_1522185_5	331869.BAL199_26042	1.579e-28	123.0	2CEUC@1|root,32S0I@2|Bacteria,1MZ90@1224|Proteobacteria,2UCBC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1522185_7	1499967.BAYZ01000014_gene6398	4.803e-19	89.0	COG4636@1|root,COG4636@2|Bacteria	2|Bacteria	D	protein conserved in cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
CMS1_k127_1522185_10	1122602.ATXP01000021_gene139	0.0004873	46.0	COG1961@1|root,COG1961@2|Bacteria,2I8HV@201174|Actinobacteria	201174|Actinobacteria	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
CMS1_k127_1522185_2	373903.Hore_08260	1.626e-72	255.0	COG1836@1|root,COG1836@2|Bacteria,1V7I1@1239|Firmicutes,24GQ3@186801|Clostridia	186801|Clostridia	I	Integral membrane protein DUF92	-	-	-	-	-	-	-	-	-	-	-	-	DUF92
CMS1_k127_1522185_1	765420.OSCT_0996	1.571e-85	297.0	COG0265@1|root,COG0265@2|Bacteria,2G6KV@200795|Chloroflexi,375DX@32061|Chloroflexia	32061|Chloroflexia	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	1.3.1.74	ko:K08070	-	-	-	-	ko00000,ko01000	-	-	-	PDZ_2,Trypsin_2
CMS1_k127_1522185_3	1280390.CBQR020000014_gene366	8.26e-63	244.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,26TP2@186822|Paenibacillaceae	91061|Bacilli	KLT	serine threonine protein kinase	prkC	GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
CMS1_k127_1522185_0	926550.CLDAP_16140	2.363e-100	336.0	COG1215@1|root,COG1215@2|Bacteria,2G6E4@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_2_3,Glycos_transf_2
CMS1_k127_1522185_9	926550.CLDAP_12350	5.874e-11	74.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	3.4.21.107,3.5.1.28	ko:K01448,ko:K04771	ko01503,ko02020,map01503,map02020	M00727,M00728	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko03036,ko03110	-	-	-	SH3_3
CMS1_k127_1522185_6	403833.Pmob_0005	1.695e-22	98.0	COG5559@1|root,338W9@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2281)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2281
CMS1_k127_1522185_4	195522.BD01_0581	1.047e-38	148.0	COG2402@1|root,arCOG05297@2157|Archaea,2Y41I@28890|Euryarchaeota,244ID@183968|Thermococci	183968|Thermococci	V	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
CMS1_k127_1522185_8	926550.CLDAP_12370	4.565e-14	78.0	COG5305@1|root,COG5305@2|Bacteria,2G7EE@200795|Chloroflexi	200795|Chloroflexi	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1530090_4	926550.CLDAP_13520	1.892e-11	67.0	COG2128@1|root,COG2128@2|Bacteria	2|Bacteria	S	hydroperoxide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS1_k127_1530090_3	1122918.KB907253_gene3302	5.831e-47	182.0	COG0395@1|root,COG0395@2|Bacteria,1V0I1@1239|Firmicutes,4HE37@91061|Bacilli,274NH@186822|Paenibacillaceae	91061|Bacilli	G	ABC transporter permease	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_1530090_1	1536774.H70357_04035	8.897e-55	204.0	COG1175@1|root,COG1175@2|Bacteria,1TRC0@1239|Firmicutes,4I67T@91061|Bacilli,26R7W@186822|Paenibacillaceae	91061|Bacilli	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_1530090_2	935845.JADQ01000022_gene4057	1.608e-50	197.0	COG1653@1|root,COG1653@2|Bacteria,1TXUQ@1239|Firmicutes,4I6X4@91061|Bacilli,26VDA@186822|Paenibacillaceae	91061|Bacilli	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
CMS1_k127_1530090_0	269797.Mbar_A2771	6.096e-149	475.0	COG2133@1|root,arCOG02796@2157|Archaea,2Y6WR@28890|Euryarchaeota,2NACH@224756|Methanomicrobia	224756|Methanomicrobia	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
CMS1_k127_1536116_6	319795.Dgeo_2865	6.402e-26	109.0	COG1028@1|root,COG1028@2|Bacteria,1WJW2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	IQ	with different specificities (related to short-chain alcohol	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS1_k127_1536116_2	309801.trd_1951	9.578e-116	381.0	COG0601@1|root,COG0601@2|Bacteria,2GAQS@200795|Chloroflexi,27YWJ@189775|Thermomicrobia	189775|Thermomicrobia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_1536116_4	309801.trd_1950	2.514e-91	309.0	COG1173@1|root,COG1173@2|Bacteria,2G8EC@200795|Chloroflexi,27YUP@189775|Thermomicrobia	189775|Thermomicrobia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_1536116_1	1382356.JQMP01000001_gene960	8.66e-125	407.0	COG0444@1|root,COG0444@2|Bacteria,2GBE3@200795|Chloroflexi,27Z2B@189775|Thermomicrobia	189775|Thermomicrobia	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
CMS1_k127_1536116_3	1382356.JQMP01000001_gene959	3.005e-113	376.0	COG4608@1|root,COG4608@2|Bacteria,2GARG@200795|Chloroflexi,27Z3W@189775|Thermomicrobia	189775|Thermomicrobia	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
CMS1_k127_1536116_0	1382356.JQMP01000001_gene961	2.339e-146	484.0	COG0747@1|root,COG0747@2|Bacteria,2GASZ@200795|Chloroflexi,27YY9@189775|Thermomicrobia	189775|Thermomicrobia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_1536116_5	1236973.JCM9157_3564	2.799e-30	134.0	COG0673@1|root,COG0673@2|Bacteria,1TQ72@1239|Firmicutes,4HCS4@91061|Bacilli,1ZCPA@1386|Bacillus	91061|Bacilli	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_1536116_7	1121346.KB899813_gene2160	7.489e-06	54.0	COG1653@1|root,COG1653@2|Bacteria,1TPX9@1239|Firmicutes,4HCP7@91061|Bacilli,26RXZ@186822|Paenibacillaceae	91061|Bacilli	G	ABC-type sugar transport system, periplasmic component	mmbP	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1
CMS1_k127_1541427_3	1125863.JAFN01000001_gene1552	2.372e-137	452.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria	2|Bacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,Fer4_4,Fer4_7,NAD_binding_8,Pyr_redox_2
CMS1_k127_1541427_14	1265505.ATUG01000003_gene623	1.081e-22	101.0	COG1908@1|root,COG1908@2|Bacteria,1RI0K@1224|Proteobacteria,42SSK@68525|delta/epsilon subdivisions,2WPF9@28221|Deltaproteobacteria,2MQ22@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	FlpD
CMS1_k127_1541427_13	1121468.AUBR01000040_gene1730	5.862e-23	100.0	COG1908@1|root,COG1908@2|Bacteria,1V638@1239|Firmicutes,24J0E@186801|Clostridia,42IDY@68295|Thermoanaerobacterales	186801|Clostridia	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	FlpD
CMS1_k127_1541427_5	1125863.JAFN01000001_gene1549	5.238e-93	310.0	COG4656@1|root,COG4656@2|Bacteria,1MWAX@1224|Proteobacteria,42NJM@68525|delta/epsilon subdivisions,2WJJB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Methylene-tetrahydrofolate reductase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	MTHFR_C
CMS1_k127_1541427_4	1125863.JAFN01000001_gene1548	5.721e-124	406.0	COG0685@1|root,COG0685@2|Bacteria,1MXTZ@1224|Proteobacteria,42NTS@68525|delta/epsilon subdivisions,2WK04@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Methylenetetrahydrofolate reductase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhD,MTHFR
CMS1_k127_1541427_11	880072.Desac_2968	1.05e-39	154.0	COG1247@1|root,COG1247@2|Bacteria,1PBZE@1224|Proteobacteria,42VVQ@68525|delta/epsilon subdivisions,2WR9W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_4
CMS1_k127_1541427_2	1125863.JAFN01000001_gene1547	4.755e-150	487.0	COG1150@1|root,COG2048@1|root,COG1150@2|Bacteria,COG2048@2|Bacteria,1N37J@1224|Proteobacteria,42P51@68525|delta/epsilon subdivisions,2WK1J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	heterodisulfide reductase	hdrB	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
CMS1_k127_1541427_12	247490.KSU1_C1368	9.233e-36	146.0	COG0639@1|root,COG0639@2|Bacteria,2IYXT@203682|Planctomycetes	203682|Planctomycetes	T	TIGRFAM phosphoesterase, MJ0936 family	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
CMS1_k127_1541427_15	671143.DAMO_2796	0.0008097	47.0	COG1142@1|root,COG1142@2|Bacteria,2NQ2V@2323|unclassified Bacteria	2|Bacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_11,Fer4_3,Fer4_4,Fer4_6,Fer4_7,Fer4_9
CMS1_k127_1541427_9	477974.Daud_0108	1.153e-51	192.0	COG1810@1|root,COG1905@1|root,COG1810@2|Bacteria,COG1905@2|Bacteria,1V737@1239|Firmicutes,24HFB@186801|Clostridia,261VF@186807|Peptococcaceae	186801|Clostridia	C	PFAM Respiratory-chain NADH dehydrogenase 24 Kd subunit	nuoE	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
CMS1_k127_1541427_7	880072.Desac_1833	4.624e-81	278.0	COG3640@1|root,COG3640@2|Bacteria,1RB02@1224|Proteobacteria,42NBP@68525|delta/epsilon subdivisions,2WKS7@28221|Deltaproteobacteria,2MQCI@213462|Syntrophobacterales	28221|Deltaproteobacteria	D	PFAM CobQ CobB MinD ParA nucleotide binding domain	cooC	-	-	ko:K07321	-	-	-	-	ko00000	-	-	-	CbiA
CMS1_k127_1541427_10	485913.Krac_9919	3.293e-43	164.0	COG3247@1|root,COG3247@2|Bacteria	2|Bacteria	U	response to pH	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
CMS1_k127_1541427_6	1131730.BAVI_07816	5.55e-93	321.0	COG2239@1|root,COG2239@2|Bacteria,1TP4V@1239|Firmicutes,4IBJC@91061|Bacilli,1ZH63@1386|Bacillus	91061|Bacilli	P	MgtE intracellular N domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,MgtE_N
CMS1_k127_1541427_8	926550.CLDAP_01500	2.127e-65	240.0	COG0628@1|root,COG0628@2|Bacteria,2G6TV@200795|Chloroflexi	200795|Chloroflexi	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
CMS1_k127_1541427_0	926550.CLDAP_20730	0.0	1172.0	COG0058@1|root,COG0058@2|Bacteria,2G5KG@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycosyl transferase, family 35	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
CMS1_k127_1541427_1	338966.Ppro_0419	1.796e-320	992.0	COG1523@1|root,COG1523@2|Bacteria,1MU19@1224|Proteobacteria,42P3J@68525|delta/epsilon subdivisions,2WKFS@28221|Deltaproteobacteria,43U1C@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
CMS1_k127_1550947_3	1408254.T458_09100	1.621e-114	378.0	COG0604@1|root,COG0604@2|Bacteria,1TQ0M@1239|Firmicutes,4HA8M@91061|Bacilli,26QXS@186822|Paenibacillaceae	91061|Bacilli	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
CMS1_k127_1550947_2	479434.Sthe_1923	2.637e-140	454.0	COG0715@1|root,COG0715@2|Bacteria	2|Bacteria	P	thiamine-containing compound biosynthetic process	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	DUF3500
CMS1_k127_1550947_0	926550.CLDAP_06490	9.608e-277	871.0	COG1529@1|root,COG1529@2|Bacteria,2G65D@200795|Chloroflexi	200795|Chloroflexi	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
CMS1_k127_1550947_7	926550.CLDAP_06500	2.407e-68	240.0	COG2080@1|root,COG2080@2|Bacteria,2G6NT@200795|Chloroflexi	200795|Chloroflexi	C	2Fe-2S -binding domain protein	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
CMS1_k127_1550947_4	926550.CLDAP_06510	1.612e-93	315.0	COG1319@1|root,COG1319@2|Bacteria,2G8QI@200795|Chloroflexi	200795|Chloroflexi	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
CMS1_k127_1550947_1	635013.TherJR_0239	4.57e-164	534.0	COG1032@1|root,COG1032@2|Bacteria,1UZQC@1239|Firmicutes,24PDA@186801|Clostridia	186801|Clostridia	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
CMS1_k127_1550947_6	1121459.AQXE01000011_gene2381	6.797e-74	259.0	COG1266@1|root,COG1266@2|Bacteria,1PD7P@1224|Proteobacteria,435PI@68525|delta/epsilon subdivisions,2X03C@28221|Deltaproteobacteria,2MA9B@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
CMS1_k127_1550947_9	1499967.BAYZ01000025_gene296	7.781e-49	179.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
CMS1_k127_1550947_5	1157490.EL26_02245	1.4e-84	299.0	COG2334@1|root,COG2334@2|Bacteria,1TSRC@1239|Firmicutes,4HEJ3@91061|Bacilli	91061|Bacilli	S	homoserine kinase type II (protein kinase fold)	yerI	-	-	-	-	-	-	-	-	-	-	-	APH
CMS1_k127_1550947_8	1499967.BAYZ01000120_gene3420	5.819e-53	192.0	COG2020@1|root,COG2020@2|Bacteria,2NR07@2323|unclassified Bacteria	2|Bacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
CMS1_k127_1552746_1	1089551.KE386572_gene1923	8.072e-58	204.0	COG2030@1|root,COG2030@2|Bacteria,1REMU@1224|Proteobacteria,2U9C8@28211|Alphaproteobacteria,4BS2S@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
CMS1_k127_1552746_3	1173027.Mic7113_2654	2.632e-40	157.0	COG1670@1|root,COG1670@2|Bacteria,1G6F2@1117|Cyanobacteria	1117|Cyanobacteria	J	COGs COG1670 Acetyltransferase including N-acetylase of ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
CMS1_k127_1552746_4	797210.Halxa_1559	1.251e-17	92.0	arCOG10292@1|root,arCOG10292@2157|Archaea,2XWF1@28890|Euryarchaeota,23S1Z@183963|Halobacteria	183963|Halobacteria	S	protein conserved in bacteria	-	-	-	ko:K09992	-	-	-	-	ko00000	-	-	-	ThuA
CMS1_k127_1552746_2	326427.Cagg_3594	5.558e-51	189.0	COG0526@1|root,COG3118@1|root,COG0526@2|Bacteria,COG3118@2|Bacteria,2G6U1@200795|Chloroflexi,375KH@32061|Chloroflexia	32061|Chloroflexia	O	TIGRFAM thioredoxin	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
CMS1_k127_1552746_0	1128421.JAGA01000002_gene1750	1.573e-74	252.0	COG0667@1|root,COG0667@2|Bacteria,2NP23@2323|unclassified Bacteria	2|Bacteria	C	Aldo/keto reductase family	yghZ	-	-	ko:K19265	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
CMS1_k127_155286_2	316274.Haur_1430	1.629e-30	138.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2G699@200795|Chloroflexi,3764S@32061|Chloroflexia	200795|Chloroflexi	T	PFAM adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
CMS1_k127_155286_1	251221.35210787	2.747e-31	128.0	COG5485@1|root,COG5485@2|Bacteria,1G6RM@1117|Cyanobacteria	1117|Cyanobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
CMS1_k127_155286_3	1463901.JOIY01000028_gene4132	1.008e-08	62.0	COG5485@1|root,COG5485@2|Bacteria,2GJYB@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
CMS1_k127_155286_0	485913.Krac_7480	1.254e-38	154.0	COG3629@1|root,COG3629@2|Bacteria	2|Bacteria	K	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
CMS1_k127_1554719_7	671143.DAMO_1690	5.307e-40	156.0	COG0664@1|root,COG0664@2|Bacteria,2NPVK@2323|unclassified Bacteria	2|Bacteria	K	Transcriptional regulator, Crp Fnr family	-	-	-	ko:K10914,ko:K21563	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CMS1_k127_1554719_3	1128421.JAGA01000003_gene3598	1.021e-63	245.0	COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GAF_2,GAF_3,HATPase_c,HATPase_c_2,HWE_HK,HisKA,PAS,PAS_3,PAS_4,PAS_9,SpoIIE
CMS1_k127_1554719_4	1123511.KB905843_gene1034	3.354e-62	223.0	COG0745@1|root,COG0745@2|Bacteria,1UDAQ@1239|Firmicutes,4H230@909932|Negativicutes	909932|Negativicutes	T	Two component transcriptional regulator, winged helix family protein	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_1554719_8	926569.ANT_05270	7.225e-39	152.0	COG1999@1|root,COG1999@2|Bacteria,2G6UW@200795|Chloroflexi	200795|Chloroflexi	S	Electron transport protein SCO1 SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
CMS1_k127_1554719_6	1380355.JNIJ01000050_gene120	7.698e-41	160.0	COG2836@1|root,COG2836@2|Bacteria,1PJEN@1224|Proteobacteria,2U5FK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2
CMS1_k127_1554719_2	326298.Suden_1985	8.834e-80	288.0	COG2010@1|root,COG3391@1|root,COG2010@2|Bacteria,COG3391@2|Bacteria,1N3PN@1224|Proteobacteria,42Q19@68525|delta/epsilon subdivisions,2YNSV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	nitrite reductase	-	-	1.7.2.1,1.7.99.1	ko:K15864	ko00910,ko01120,map00910,map01120	M00529	R00143,R00783,R00785	RC00086,RC02797	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_D1,Cytochrome_CBB3
CMS1_k127_1554719_5	867903.ThesuDRAFT_01183	9.029e-62	218.0	COG1622@1|root,COG1622@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2
CMS1_k127_1554719_0	867903.ThesuDRAFT_01182	1.539e-188	602.0	COG0843@1|root,COG0843@2|Bacteria,1TRC2@1239|Firmicutes	1239|Firmicutes	C	COG0843 Heme copper-type cytochrome quinol oxidases, subunit 1	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
CMS1_k127_1554719_1	935261.JAGL01000032_gene3819	1.779e-99	336.0	COG2132@1|root,COG2132@2|Bacteria,1MV74@1224|Proteobacteria,2U1BK@28211|Alphaproteobacteria,43JBX@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	Q	nitrite reductase, copper-containing	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3,Cytochrom_C
CMS1_k127_156553_0	344747.PM8797T_27020	5.205e-185	589.0	COG1012@1|root,COG1012@2|Bacteria,2IYRE@203682|Planctomycetes	203682|Planctomycetes	C	ketoglutarate semialdehyde dehydrogenase	-	-	1.2.1.26	ko:K13877	ko00040,ko00053,map00040,map00053	-	R00264	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
CMS1_k127_156553_2	1121472.AQWN01000001_gene238	1.514e-90	313.0	COG3875@1|root,COG3875@2|Bacteria,1TQ1C@1239|Firmicutes,247PH@186801|Clostridia,261WJ@186807|Peptococcaceae	186801|Clostridia	S	conserved protein (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
CMS1_k127_156553_13	396014.BF93_18755	1.982e-10	74.0	COG1376@1|root,COG1376@2|Bacteria,2GQ7D@201174|Actinobacteria,4FBRA@85020|Dermabacteraceae	201174|Actinobacteria	S	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,YkuD
CMS1_k127_156553_6	316274.Haur_0717	3.112e-61	233.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,2G5NM@200795|Chloroflexi,3755B@32061|Chloroflexia	200795|Chloroflexi	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS1_k127_156553_8	247490.KSU1_D0432	4.079e-48	186.0	COG1262@1|root,COG1262@2|Bacteria,2IXQ0@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
CMS1_k127_156553_14	404380.Gbem_0095	1.516e-06	59.0	COG2864@1|root,COG2864@2|Bacteria,1NJEJ@1224|Proteobacteria,42NQM@68525|delta/epsilon subdivisions,2WK76@28221|Deltaproteobacteria,43U5U@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Cytochrome c3	cbcY	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Ni_hydr_CYTB
CMS1_k127_156553_4	903818.KI912268_gene2328	4.955e-70	248.0	COG0437@1|root,COG0437@2|Bacteria,3Y5RE@57723|Acidobacteria	57723|Acidobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_11
CMS1_k127_156553_3	945713.IALB_2427	2.178e-90	313.0	COG5557@1|root,COG5557@2|Bacteria	2|Bacteria	C	Polysulphide reductase, NrfD	hmcC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	NrfD
CMS1_k127_156553_12	458817.Shal_2928	7.076e-13	78.0	COG3005@1|root,COG3005@2|Bacteria,1R4UP@1224|Proteobacteria,1RYPM@1236|Gammaproteobacteria,2Q8MP@267890|Shewanellaceae	1236|Gammaproteobacteria	C	TIGRFAM cytochrome C family protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Paired_CXXCH_1
CMS1_k127_156553_15	335543.Sfum_0360	0.000119	49.0	COG0789@1|root,COG0789@2|Bacteria,1NP97@1224|Proteobacteria,43DNH@68525|delta/epsilon subdivisions,2X38J@28221|Deltaproteobacteria,2MSE8@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	Transcriptional regulator, MerR family	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
CMS1_k127_156553_5	1382306.JNIM01000001_gene1045	3.019e-68	238.0	COG2197@1|root,COG2197@2|Bacteria,2G6PA@200795|Chloroflexi	200795|Chloroflexi	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS1_k127_156553_7	926550.CLDAP_25550	4.07e-58	226.0	COG2203@1|root,COG4585@1|root,COG5002@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,COG5002@2|Bacteria,2G8PE@200795|Chloroflexi	200795|Chloroflexi	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
CMS1_k127_156553_9	696281.Desru_2695	4.014e-38	156.0	COG1150@1|root,COG1150@2|Bacteria	2|Bacteria	C	4Fe-4S dicluster domain	-	-	1.17.1.9	ko:K00125,ko:K03646	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000,ko02000	2.C.1.2	-	-	Fer4,Fer4_17,Fer4_8,FrhB_FdhB_C
CMS1_k127_156553_1	1449126.JQKL01000043_gene1900	2.145e-153	506.0	COG0247@1|root,COG0247@2|Bacteria,1TPG1@1239|Firmicutes,24BBE@186801|Clostridia	186801|Clostridia	C	Fe-S oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8,Nitrate_red_gam
CMS1_k127_156553_11	194439.CT0302	3.152e-15	83.0	COG0723@1|root,COG0723@2|Bacteria,1FE1T@1090|Chlorobi	1090|Chlorobi	C	PFAM Rieske 2Fe-2S domain protein	-	-	1.10.9.1	ko:K02636	ko00195,ko01100,map00195,map01100	M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	CytB6-F_Fe-S,Rieske
CMS1_k127_156553_10	1232410.KI421425_gene1569	3.076e-20	96.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,42MD6@68525|delta/epsilon subdivisions,2WPA2@28221|Deltaproteobacteria,43TZT@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Cytochrome b(C-terminal)/b6/petD	cbcW	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_B_N_2,Cytochrom_C,Cytochrome_B,Cytochrome_CBB3
CMS1_k127_1570109_3	671143.DAMO_0822	5.277e-78	277.0	COG2864@1|root,COG2864@2|Bacteria,2NQBN@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome c554 and c-prime	-	-	-	ko:K03620	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Ni_hydr_CYTB
CMS1_k127_1570109_1	926569.ANT_26980	1.079e-90	320.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C552,Cytochrom_c3_2,Paired_CXXCH_1
CMS1_k127_1570109_2	926569.ANT_26970	2.591e-90	308.0	COG2010@1|root,COG2864@1|root,COG2010@2|Bacteria,COG2864@2|Bacteria	2|Bacteria	C	formate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Ni_hydr_CYTB,PSCyt1
CMS1_k127_1570109_0	926569.ANT_21930	1.676e-254	804.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	3.2.1.81,3.2.1.97	ko:K01219,ko:K17624	-	-	-	-	ko00000,ko01000	-	GH101	-	Big_2,CBM_6,Cytochrome_C7,F5_F8_type_C,Glyco_hyd_101C,Glyco_hydro_101,WxL
CMS1_k127_1570109_4	644966.Tmar_1372	2.952e-63	226.0	COG2197@1|root,COG2197@2|Bacteria,1TQ1U@1239|Firmicutes,25B1X@186801|Clostridia,3WDTH@538999|Clostridiales incertae sedis	186801|Clostridia	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K11618	ko02020,map02020	M00481,M00754	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
CMS1_k127_1570109_5	443144.GM21_0254	0.000595	50.0	COG1276@1|root,COG4892@1|root,COG1276@2|Bacteria,COG4892@2|Bacteria,1N3DP@1224|Proteobacteria,42U1X@68525|delta/epsilon subdivisions,2WQFI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM Cytochrome b5	-	-	-	-	-	-	-	-	-	-	-	-	CopD,Cyt-b5
CMS1_k127_157194_10	479434.Sthe_1139	7.724e-58	212.0	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	-	ko:K02847	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	9.B.67.4,9.B.67.5	-	-	Wzy_C
CMS1_k127_157194_2	479434.Sthe_1137	6.625e-129	421.0	COG0438@1|root,COG0438@2|Bacteria,2G99J@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4
CMS1_k127_157194_4	479434.Sthe_1135	1.662e-105	357.0	COG0438@1|root,COG0438@2|Bacteria,2G9B8@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS1_k127_157194_0	479434.Sthe_1134	6.624e-189	599.0	COG1004@1|root,COG1004@2|Bacteria,2G62F@200795|Chloroflexi,27XRP@189775|Thermomicrobia	2|Bacteria	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	algD	-	1.1.1.132,1.1.1.22	ko:K00012,ko:K00066	ko00040,ko00051,ko00053,ko00520,ko01100,ko02020,map00040,map00051,map00053,map00520,map01100,map02020	M00014,M00129,M00361,M00362	R00286,R00880	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
CMS1_k127_157194_3	697282.Mettu_3902	3.697e-124	410.0	COG0438@1|root,COG0438@2|Bacteria,1QTH7@1224|Proteobacteria,1RXHP@1236|Gammaproteobacteria,1XFTD@135618|Methylococcales	135618|Methylococcales	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
CMS1_k127_157194_6	1124780.ANNU01000062_gene568	1.354e-78	272.0	2D326@1|root,32TE3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1,Sulfotransfer_3
CMS1_k127_157194_9	105559.Nwat_2843	1.909e-68	240.0	COG2244@1|root,COG2244@2|Bacteria,1R9I0@1224|Proteobacteria,1RP3V@1236|Gammaproteobacteria,1WYZU@135613|Chromatiales	135613|Chromatiales	S	PFAM Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_3,Polysacc_synt_C
CMS1_k127_157194_8	247490.KSU1_C0431	9.815e-75	259.0	COG2244@1|root,COG2244@2|Bacteria,2J1D3@203682|Planctomycetes	203682|Planctomycetes	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_3
CMS1_k127_157194_11	402881.Plav_1912	1.824e-55	208.0	COG0615@1|root,COG0615@2|Bacteria,1N9T6@1224|Proteobacteria	1224|Proteobacteria	IM	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
CMS1_k127_157194_1	338966.Ppro_2168	2.597e-174	559.0	COG3919@1|root,COG3919@2|Bacteria,1N13P@1224|Proteobacteria,42WGT@68525|delta/epsilon subdivisions,2WRKR@28221|Deltaproteobacteria,43VRY@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_3
CMS1_k127_157194_12	693661.Arcve_0556	3.507e-54	197.0	COG0110@1|root,arCOG01848@2157|Archaea,2XWJM@28890|Euryarchaeota,2474T@183980|Archaeoglobi	183980|Archaeoglobi	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
CMS1_k127_157194_7	994479.GL877878_gene3233	1.763e-78	274.0	COG0707@1|root,COG2348@1|root,COG0707@2|Bacteria,COG2348@2|Bacteria,2I7BS@201174|Actinobacteria,4E9SH@85010|Pseudonocardiales	201174|Actinobacteria	V	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
CMS1_k127_1585865_1	926550.CLDAP_16780	5.513e-198	630.0	COG5598@1|root,COG5598@2|Bacteria	2|Bacteria	H	trimethylamine methyltransferase	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
CMS1_k127_1585865_3	234267.Acid_7336	4.29e-154	503.0	COG1233@1|root,COG1233@2|Bacteria,3Y3T3@57723|Acidobacteria	57723|Acidobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
CMS1_k127_1585865_4	1173022.Cri9333_0569	1.502e-54	195.0	2AFHA@1|root,315HT@2|Bacteria,1G5WD@1117|Cyanobacteria,1HBUI@1150|Oscillatoriales	1117|Cyanobacteria	J	S23 ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
CMS1_k127_1585865_0	204669.Acid345_1270	2.292e-246	769.0	COG1233@1|root,COG1233@2|Bacteria,3Y3T3@57723|Acidobacteria,2JME5@204432|Acidobacteriia	204432|Acidobacteriia	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_8
CMS1_k127_1585865_2	452637.Oter_2190	4.269e-158	509.0	COG1472@1|root,COG1472@2|Bacteria,46UPF@74201|Verrucomicrobia,3K900@414999|Opitutae	414999|Opitutae	G	PFAM glycoside hydrolase family 3 domain protein	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
CMS1_k127_1595040_2	309801.trd_1787	1.332e-150	488.0	COG1009@1|root,COG1009@2|Bacteria,2G5NJ@200795|Chloroflexi,27XR2@189775|Thermomicrobia	189775|Thermomicrobia	C	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
CMS1_k127_1595040_7	926550.CLDAP_08680	2.578e-30	122.0	COG0713@1|root,COG0713@2|Bacteria,2G6TP@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
CMS1_k127_1595040_6	324602.Caur_2905	2.55e-32	132.0	COG0839@1|root,COG0839@2|Bacteria,2G78H@200795|Chloroflexi,375QH@32061|Chloroflexia	32061|Chloroflexia	C	Belongs to the complex I subunit 6 family	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
CMS1_k127_1595040_5	926550.CLDAP_08700	2.691e-57	205.0	COG1143@1|root,COG1143@2|Bacteria,2G6P8@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338,ko:K05580	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
CMS1_k127_1595040_3	926550.CLDAP_08710	3.05e-113	375.0	COG1005@1|root,COG1005@2|Bacteria,2G62Y@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
CMS1_k127_1595040_0	1128421.JAGA01000002_gene144	3.298e-254	811.0	COG3383@1|root,COG3383@2|Bacteria,2NNQ6@2323|unclassified Bacteria	2|Bacteria	C	Molydopterin dinucleotide binding domain	nuoG	-	1.17.1.9,1.6.5.3	ko:K00123,ko:K00336	ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200	M00144	R00519,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Fer4,Fer4_6,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
CMS1_k127_1595040_1	945713.IALB_0026	1.541e-182	576.0	COG1830@1|root,COG1830@2|Bacteria	2|Bacteria	G	lyase activity	fbaB	GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016829,GO:0016830,GO:0016832,GO:0042802,GO:0044424,GO:0044444,GO:0044464	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	iETEC_1333.ETEC_2236,iSBO_1134.SBO_0918,iUMNK88_1353.UMNK88_2640	DeoC
CMS1_k127_1595040_4	1382306.JNIM01000001_gene3467	2.081e-57	204.0	COG1894@1|root,COG1894@2|Bacteria,2G5W1@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
CMS1_k127_1600814_8	1410620.SHLA_34c000710	1.101e-42	164.0	COG1940@1|root,COG1940@2|Bacteria,1MU94@1224|Proteobacteria,2TRRU@28211|Alphaproteobacteria,4BC7B@82115|Rhizobiaceae	28211|Alphaproteobacteria	GK	ROK family	mak	-	2.7.1.2,2.7.1.4,2.7.1.59	ko:K00845,ko:K00847,ko:K00884	ko00010,ko00051,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00051,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R00760,R00867,R01201,R01600,R01786,R03920	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
CMS1_k127_1600814_6	1410620.SHLA_34c000720	1.464e-62	228.0	COG2222@1|root,COG2222@2|Bacteria,1R57F@1224|Proteobacteria	1224|Proteobacteria	M	sugar isomerase	-	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	SIS
CMS1_k127_1600814_3	309798.COPRO5265_1583	5.895e-99	349.0	COG1404@1|root,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,24CD5@186801|Clostridia,42G7V@68295|Thermoanaerobacterales	186801|Clostridia	O	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	ko:K13274,ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Big_2,CW_binding_2,Peptidase_S8,SLH
CMS1_k127_1600814_5	926569.ANT_15670	4.418e-66	250.0	COG0642@1|root,COG2205@2|Bacteria	926569.ANT_15670|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1600814_2	926550.CLDAP_21800	2.273e-99	333.0	COG0524@1|root,COG0524@2|Bacteria,2G6QX@200795|Chloroflexi	200795|Chloroflexi	G	PFAM PfkB domain protein	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
CMS1_k127_1600814_1	1382306.JNIM01000001_gene3914	1.499e-257	812.0	COG0855@1|root,COG0855@2|Bacteria,2G68J@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
CMS1_k127_1600814_10	1094980.Mpsy_0378	1.178e-23	109.0	COG1437@1|root,arCOG05222@1|root,arCOG01723@2157|Archaea,arCOG05222@2157|Archaea,2Y3MX@28890|Euryarchaeota,2NAVU@224756|Methanomicrobia	224756|Methanomicrobia	F	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD
CMS1_k127_1600814_11	632245.CLP_3391	0.0001792	48.0	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,248EM@186801|Clostridia,36E5A@31979|Clostridiaceae	186801|Clostridia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
CMS1_k127_1600814_4	330214.NIDE0397	3.155e-80	273.0	COG0036@1|root,COG0036@2|Bacteria,3J0IZ@40117|Nitrospirae	40117|Nitrospirae	G	Ribulose-phosphate 3 epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
CMS1_k127_1600814_0	671143.DAMO_2651	3.233e-298	928.0	COG0021@1|root,COG0021@2|Bacteria,2NS3T@2323|unclassified Bacteria	2|Bacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
CMS1_k127_1600814_9	357808.RoseRS_0338	6.192e-27	127.0	COG2204@1|root,COG2206@1|root,COG2204@2|Bacteria,COG2206@2|Bacteria,2GBKK@200795|Chloroflexi,3781M@32061|Chloroflexia	32061|Chloroflexia	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,Response_reg
CMS1_k127_1600814_7	1041930.Mtc_0845	4.739e-48	192.0	COG0642@1|root,arCOG02338@1|root,arCOG02338@2157|Archaea,arCOG07619@2157|Archaea,2Y7TB@28890|Euryarchaeota,2NBMD@224756|Methanomicrobia	224756|Methanomicrobia	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
CMS1_k127_161225_4	99598.Cal7507_1264	9.897e-26	108.0	COG0111@1|root,COG0111@2|Bacteria,1G417@1117|Cyanobacteria,1HTW5@1161|Nostocales	1117|Cyanobacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
CMS1_k127_161225_0	926550.CLDAP_00350	7.735e-160	523.0	COG0497@1|root,COG0497@2|Bacteria,2G5V1@200795|Chloroflexi	200795|Chloroflexi	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
CMS1_k127_161225_3	926569.ANT_00520	3.875e-30	126.0	COG3063@1|root,COG3063@2|Bacteria,2G79Z@200795|Chloroflexi	200795|Chloroflexi	NU	Type IV pilus biogenesis stability protein PilW	-	-	-	-	-	-	-	-	-	-	-	-	zf-B_box
CMS1_k127_161225_2	926550.CLDAP_14750	8.656e-76	263.0	COG0061@1|root,COG0061@2|Bacteria,2G6NK@200795|Chloroflexi	200795|Chloroflexi	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
CMS1_k127_161225_1	926550.CLDAP_18940	4.288e-81	282.0	COG0472@1|root,COG0472@2|Bacteria,2G6H5@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 4	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
CMS1_k127_1621778_0	926550.CLDAP_13490	1.507e-231	741.0	COG1205@1|root,COG1403@1|root,COG1205@2|Bacteria,COG1403@2|Bacteria,2G605@200795|Chloroflexi	200795|Chloroflexi	L	DEAD DEAH box helicase domain protein	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,HNH,Helicase_C
CMS1_k127_1621778_2	1120999.JONM01000003_gene2723	1.575e-43	165.0	COG1510@1|root,COG1510@2|Bacteria,1RA49@1224|Proteobacteria,2VQNT@28216|Betaproteobacteria,2KQ5T@206351|Neisseriales	206351|Neisseriales	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
CMS1_k127_1621778_1	765420.OSCT_3226	1.507e-43	174.0	COG1630@1|root,COG1630@2|Bacteria,2G68Z@200795|Chloroflexi,374ZP@32061|Chloroflexia	32061|Chloroflexia	S	NurA	-	-	-	-	-	-	-	-	-	-	-	-	NurA
CMS1_k127_162880_4	592015.HMPREF1705_00560	6.658e-06	50.0	COG2886@1|root,COG2886@2|Bacteria	2|Bacteria	E	Uncharacterised protein family (UPF0175)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0175
CMS1_k127_162880_3	880073.Calab_2009	3.499e-07	57.0	COG1061@1|root,COG1061@2|Bacteria,2NNPQ@2323|unclassified Bacteria	2|Bacteria	KL	Type III restriction enzyme res subunit	-	-	3.1.21.5	ko:K01156	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Helicase_C,ResIII
CMS1_k127_162880_0	926569.ANT_20970	7.709e-92	311.0	COG1121@1|root,COG1121@2|Bacteria,2G7X2@200795|Chloroflexi	200795|Chloroflexi	P	PFAM ABC transporter related	-	-	-	ko:K09820,ko:K11710	ko02010,map02010	M00243,M00319	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15	-	-	ABC_tran
CMS1_k127_162880_1	926569.ANT_20980	1.875e-90	306.0	COG1108@1|root,COG1108@2|Bacteria,2G6GH@200795|Chloroflexi	200795|Chloroflexi	P	PFAM ABC-3 protein	-	-	-	ko:K09816,ko:K09819	ko02010,map02010	M00242,M00243	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
CMS1_k127_162880_2	1128421.JAGA01000002_gene209	1.232e-39	149.0	COG1109@1|root,COG1109@2|Bacteria,2NNRE@2323|unclassified Bacteria	2|Bacteria	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	manB	GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	5.4.2.2,5.4.2.8	ko:K01840,ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	iECS88_1305.ECS88_2145,iECUMN_1333.ECUMN_2384,iUTI89_1310.UTI89_C2321	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
CMS1_k127_163146_1	1121377.KB906404_gene2877	1.362e-119	414.0	COG0515@1|root,COG0515@2|Bacteria,1WIDK@1297|Deinococcus-Thermus	1121377.KB906404_gene2877|-	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_163146_0	765420.OSCT_2127	2.585e-151	501.0	2CVPW@1|root,32SXZ@2|Bacteria,2G7DV@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_164792_0	926569.ANT_26670	1.197e-194	613.0	COG0459@1|root,COG0459@2|Bacteria,2G65N@200795|Chloroflexi	200795|Chloroflexi	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
CMS1_k127_164792_8	345219.Bcoa_1529	7.236e-34	132.0	COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,4HKEK@91061|Bacilli,1ZGZ1@1386|Bacillus	91061|Bacilli	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
CMS1_k127_164792_6	1303518.CCALI_01986	5.556e-64	234.0	COG3605@1|root,COG3920@1|root,COG3605@2|Bacteria,COG3920@2|Bacteria	2|Bacteria	T	Histidine kinase	pdtaS	-	2.1.1.80,2.7.13.3,3.1.1.61,3.1.4.52,3.6.3.17,4.2.1.75,4.6.1.1	ko:K00936,ko:K01719,ko:K01768,ko:K02030,ko:K02584,ko:K10441,ko:K13924,ko:K20962	ko00230,ko00860,ko01100,ko01110,ko01120,ko02010,ko02020,ko02025,ko02030,ko04113,ko04213,ko05111,map00230,map00860,map01100,map01110,map01120,map02010,map02020,map02025,map02030,map04113,map04213,map05111	M00121,M00212,M00236,M00506,M00695,M00839	R00089,R00434,R03165	RC00295,RC01861	ko00000,ko00001,ko00002,ko01000,ko01001,ko02000,ko02022,ko02035,ko03000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.3	-	-	GAF,GAF_2,HATPase_c,HATPase_c_2,H_kinase_N,HisKA_2,PAS,PAS_3,PAS_4,PAS_9,Response_reg,TPR_12,TPR_8
CMS1_k127_164792_7	1262914.BN533_00119	1.355e-40	158.0	COG3707@1|root,COG3707@2|Bacteria,1U6TA@1239|Firmicutes,4H1ZW@909932|Negativicutes	909932|Negativicutes	T	Response regulator receiver domain protein	pdtaR	-	-	ko:K22010	-	M00839	-	-	ko00000,ko00002,ko02022	-	-	-	ANTAR,Response_reg
CMS1_k127_164792_1	682795.AciX8_4456	3.715e-110	371.0	COG2020@1|root,COG2020@2|Bacteria,3Y79Z@57723|Acidobacteria,2JKUP@204432|Acidobacteriia	204432|Acidobacteriia	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
CMS1_k127_164792_3	682795.AciX8_4455	7.29e-80	277.0	2DTT8@1|root,32UVV@2|Bacteria,3Y74Z@57723|Acidobacteria,2JM99@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_164792_5	485913.Krac_4805	3.367e-74	258.0	COG4106@1|root,COG4106@2|Bacteria	2|Bacteria	FG	trans-aconitate 2-methyltransferase activity	-	-	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,TPMT
CMS1_k127_164792_4	1499967.BAYZ01000065_gene6085	3.156e-77	269.0	COG2423@1|root,COG2423@2|Bacteria,2NPI5@2323|unclassified Bacteria	2|Bacteria	E	Ornithine cyclodeaminase/mu-crystallin family	rapL	-	4.3.1.12	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	-	R00671	RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
CMS1_k127_164792_2	357808.RoseRS_3808	1.869e-103	348.0	COG0665@1|root,COG0665@2|Bacteria,2G6HT@200795|Chloroflexi,374X0@32061|Chloroflexia	32061|Chloroflexia	E	FAD dependent oxidoreductase	-	-	1.5.3.1	ko:K00303	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
CMS1_k127_1671949_0	1535287.JP74_08025	1.331e-49	200.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,NB-ARC,cNMP_binding
CMS1_k127_1671949_1	1123321.KB905818_gene4751	1.152e-27	125.0	COG0673@1|root,COG0673@2|Bacteria,2IAF9@201174|Actinobacteria	201174|Actinobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_1674460_4	331869.BAL199_18541	2.413e-47	173.0	COG1834@1|root,COG1834@2|Bacteria,1R7NG@1224|Proteobacteria,2U4ZK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Amidinotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Amidinotransf
CMS1_k127_1674460_2	926569.ANT_17680	3.906e-82	282.0	COG2047@1|root,COG2047@2|Bacteria	2|Bacteria	S	protein (ATP-grasp superfamily)	-	-	-	ko:K07159	-	-	-	-	ko00000	-	-	-	PAC2
CMS1_k127_1674460_0	344747.PM8797T_26465	1.667e-125	413.0	COG2706@1|root,COG2706@2|Bacteria,2IY02@203682|Planctomycetes	203682|Planctomycetes	G	COG2706 3-carboxymuconate cyclase	-	-	3.1.1.31	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Lactonase
CMS1_k127_1674460_1	926550.CLDAP_34530	5.813e-115	374.0	COG0667@1|root,COG0667@2|Bacteria,2G681@200795|Chloroflexi	200795|Chloroflexi	C	Aldo/keto reductase family	-	-	-	ko:K19265	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
CMS1_k127_1674482_2	383372.Rcas_1499	1.363e-92	312.0	COG3618@1|root,COG3618@2|Bacteria,2G7J1@200795|Chloroflexi	200795|Chloroflexi	S	Amidohydrolase	-	-	-	ko:K07046	ko00051,ko01120,map00051,map01120	-	R10689	RC00537	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2
CMS1_k127_1674482_1	234267.Acid_2317	5.504e-109	361.0	COG1171@1|root,COG1171@2|Bacteria,3Y2RI@57723|Acidobacteria	57723|Acidobacteria	E	beta' subunit	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
CMS1_k127_1674482_4	449447.MAE_06890	1.597e-28	126.0	COG4447@1|root,COG4447@2|Bacteria,1G2KP@1117|Cyanobacteria	1117|Cyanobacteria	G	PFAM BNR Asp-box repeat	-	-	-	-	-	-	-	-	-	-	-	-	BNR,PSII_BNR,Sortilin-Vps10
CMS1_k127_1674482_3	357808.RoseRS_1077	6.461e-83	296.0	COG0459@1|root,COG0459@2|Bacteria,2G65N@200795|Chloroflexi,376ZZ@32061|Chloroflexia	32061|Chloroflexia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL2	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
CMS1_k127_1674482_0	697281.Mahau_1817	3.809e-180	572.0	COG4948@1|root,COG4948@2|Bacteria,1TS0S@1239|Firmicutes,24AE7@186801|Clostridia,42ES0@68295|Thermoanaerobacterales	186801|Clostridia	M	PFAM Mandelate racemase muconate lactonizing enzyme	-	GO:0000287,GO:0003674,GO:0005488,GO:0043167,GO:0043169,GO:0046872	4.2.1.5,4.2.1.6,4.2.1.8	ko:K01683,ko:K01684,ko:K08323	ko00040,ko00052,ko01100,ko01120,map00040,map00052,map01100,map01120	M00061,M00552	R03033,R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
CMS1_k127_167479_2	525904.Tter_0264	1.13e-115	379.0	COG0395@1|root,COG0395@2|Bacteria	2|Bacteria	P	glycerophosphodiester transmembrane transport	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_167479_1	525904.Tter_0263	1.264e-128	420.0	COG1175@1|root,COG1175@2|Bacteria	2|Bacteria	P	transmembrane transport	-	-	-	ko:K02025,ko:K05814,ko:K10118,ko:K10237,ko:K10241,ko:K15771,ko:K17235,ko:K17316	ko02010,map02010	M00196,M00198,M00204,M00206,M00207,M00491,M00602,M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.17,3.A.1.1.2,3.A.1.1.23,3.A.1.1.24,3.A.1.1.28,3.A.1.1.3,3.A.1.1.30,3.A.1.1.34	-	-	BPD_transp_1
CMS1_k127_167479_3	357808.RoseRS_3622	2.684e-81	285.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
CMS1_k127_167479_4	1128421.JAGA01000002_gene1966	7.789e-65	234.0	COG1609@1|root,COG1609@2|Bacteria,2NR26@2323|unclassified Bacteria	2|Bacteria	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
CMS1_k127_167479_0	926550.CLDAP_22240	1.341e-133	443.0	COG1215@1|root,COG1215@2|Bacteria,2G952@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	2.4.1.12	ko:K00694	ko00500,ko01100,ko02026,map00500,map01100,map02026	-	R02889	RC00005	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.3.1.2,4.D.3.1.5,4.D.3.1.6	GT2	-	Cellulose_synt,Glyco_tranf_2_3,T2SSE_N
CMS1_k127_1677645_0	1121403.AUCV01000055_gene2985	2.274e-133	435.0	COG0707@1|root,COG0707@2|Bacteria,1QU89@1224|Proteobacteria	1224|Proteobacteria	M	UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase	-	-	2.4.1.315,2.4.1.46	ko:K03429,ko:K03715	ko00561,ko01100,map00561,map01100	-	R02689,R02691,R04377	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT28	-	Glyco_tran_28_C,MGDG_synth
CMS1_k127_1677645_4	309801.trd_1857	7.387e-21	94.0	COG4481@1|root,COG4481@2|Bacteria,2G9W8@200795|Chloroflexi,27YMV@189775|Thermomicrobia	189775|Thermomicrobia	S	Bacterial protein of unknown function (DUF951)	-	-	-	-	-	-	-	-	-	-	-	-	DUF951
CMS1_k127_1677645_2	1089548.KI783301_gene1185	2.665e-39	158.0	COG1994@1|root,COG1994@2|Bacteria,1V6D4@1239|Firmicutes,4HHK2@91061|Bacilli	91061|Bacilli	S	zinc metalloprotease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
CMS1_k127_1677645_5	926550.CLDAP_06120	3.777e-16	85.0	COG1418@1|root,COG1418@2|Bacteria,2G7CI@200795|Chloroflexi	200795|Chloroflexi	S	mRNA catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1677645_1	479434.Sthe_0803	4.145e-47	182.0	COG0287@1|root,COG0287@2|Bacteria,2G6BW@200795|Chloroflexi,27XQX@189775|Thermomicrobia	189775|Thermomicrobia	C	Prephenate dehydrogenase	-	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
CMS1_k127_1677645_3	665956.HMPREF1032_02902	2.072e-26	111.0	COG0110@1|root,COG2827@1|root,COG0110@2|Bacteria,COG2827@2|Bacteria,1VEZF@1239|Firmicutes,24QYU@186801|Clostridia,3WKVK@541000|Ruminococcaceae	186801|Clostridia	L	GIY-YIG catalytic domain protein	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
CMS1_k127_1695000_1	926550.CLDAP_31260	2.543e-89	300.0	COG0664@1|root,COG0664@2|Bacteria,2G6WI@200795|Chloroflexi	200795|Chloroflexi	K	PFAM Cyclic nucleotide-binding	-	-	-	ko:K10914,ko:K21564	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CMS1_k127_1695000_3	926550.CLDAP_31250	2.893e-19	91.0	2EEX1@1|root,338QB@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3307)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3307
CMS1_k127_1695000_2	1173020.Cha6605_4339	3.294e-52	201.0	COG0515@1|root,COG0642@1|root,COG0745@1|root,COG3899@1|root,COG0515@2|Bacteria,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3899@2|Bacteria,1GBKM@1117|Cyanobacteria	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,Guanylate_cyc,HATPase_c,HisKA,Pkinase
CMS1_k127_1695000_0	485913.Krac_4869	8.079e-144	464.0	COG3191@1|root,COG3191@2|Bacteria,2G83Q@200795|Chloroflexi	200795|Chloroflexi	EQ	Peptidase family S58	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S58
CMS1_k127_1725376_1	765420.OSCT_1265	6.256e-61	214.0	COG0459@1|root,COG0459@2|Bacteria,2G65N@200795|Chloroflexi,375DU@32061|Chloroflexia	32061|Chloroflexia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
CMS1_k127_1725376_3	1128421.JAGA01000002_gene949	2.997e-34	133.0	COG2261@1|root,COG2261@2|Bacteria	2|Bacteria	S	Transglycosylase associated protein	mltA	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
CMS1_k127_1725376_7	289376.THEYE_A1391	1.858e-06	54.0	COG4980@1|root,COG4980@2|Bacteria,3J1B3@40117|Nitrospirae	40117|Nitrospirae	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
CMS1_k127_1725376_2	926569.ANT_22770	4.889e-55	199.0	COG3428@1|root,COG3428@2|Bacteria,2G70V@200795|Chloroflexi	200795|Chloroflexi	S	PFAM membrane-flanked domain	-	-	-	-	-	-	-	-	-	-	-	-	SHOCT,bPH_2
CMS1_k127_1725376_5	1128421.JAGA01000002_gene949	5.08e-23	104.0	COG2261@1|root,COG2261@2|Bacteria	2|Bacteria	S	Transglycosylase associated protein	mltA	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
CMS1_k127_1725376_4	700598.Niako_0542	1.374e-29	122.0	2BZBR@1|root,32YH6@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
CMS1_k127_1725376_6	598467.BrE312_3878	9.324e-19	87.0	COG3237@1|root,COG3237@2|Bacteria,1N6X4@1224|Proteobacteria,1SDHP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the UPF0337 (CsbD) family	yjbJ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	CsbD
CMS1_k127_1725376_0	1499967.BAYZ01000036_gene2415	5.93e-232	726.0	COG0557@1|root,COG0557@2|Bacteria,2NNV2@2323|unclassified Bacteria	2|Bacteria	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnb	-	3.1.13.1	ko:K01147,ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
CMS1_k127_1732636_1	926569.ANT_10970	6.335e-174	550.0	COG4608@1|root,COG4608@2|Bacteria,2G7YH@200795|Chloroflexi	200795|Chloroflexi	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
CMS1_k127_1732636_2	926569.ANT_10960	1.669e-155	499.0	COG0444@1|root,COG0444@2|Bacteria,2G893@200795|Chloroflexi	200795|Chloroflexi	P	TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
CMS1_k127_1732636_4	309799.DICTH_1598	1.947e-111	372.0	COG1173@1|root,COG1173@2|Bacteria	2|Bacteria	P	ABC-type dipeptide oligopeptide nickel transport systems, permease components	oppC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
CMS1_k127_1732636_3	926569.ANT_10940	1.941e-147	473.0	COG0601@1|root,COG0601@2|Bacteria,2G7WN@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_1732636_0	926569.ANT_10930	1.825e-202	647.0	COG0747@1|root,COG0747@2|Bacteria,2G7TF@200795|Chloroflexi	200795|Chloroflexi	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5,TAT_signal
CMS1_k127_17379_10	118168.MC7420_3254	2.155e-14	74.0	COG5263@1|root,COG5263@2|Bacteria,1G1AI@1117|Cyanobacteria,1HASA@1150|Oscillatoriales	1117|Cyanobacteria	S	KWG Leptospira	-	-	-	-	-	-	-	-	-	-	-	-	SLH,WG_beta_rep
CMS1_k127_17379_3	649638.Trad_1840	3.233e-136	443.0	COG0823@1|root,COG0823@2|Bacteria,1WMXQ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	U	Oligogalacturonate lyase	-	-	4.2.2.6	ko:K01730	ko00040,map00040	-	R04382	RC02124,RC02427	ko00000,ko00001,ko01000	-	-	-	PD40,Pectate_lyase22
CMS1_k127_17379_0	366602.Caul_2946	4.828e-220	716.0	COG4992@1|root,COG5322@1|root,COG4992@2|Bacteria,COG5322@2|Bacteria,1R6U9@1224|Proteobacteria,2TUDK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	MA20_16020	-	2.6.1.13	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R00667	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
CMS1_k127_17379_11	1206730.BAGA01000166_gene2243	5.87e-09	60.0	COG0318@1|root,COG0318@2|Bacteria,2I2RH@201174|Actinobacteria,4G8NE@85025|Nocardiaceae	201174|Actinobacteria	IQ	AMP-binding enzyme	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C_2
CMS1_k127_17379_4	1150864.MILUP08_43535	4.401e-91	324.0	COG1960@1|root,COG1960@2|Bacteria,2GKRK@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1
CMS1_k127_17379_8	935837.JAEK01000002_gene2031	1.336e-48	185.0	COG0667@1|root,COG0667@2|Bacteria,1UKPC@1239|Firmicutes,4HCF8@91061|Bacilli,1ZQGC@1386|Bacillus	91061|Bacilli	C	Aldo/keto reductase family	tas	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS1_k127_17379_5	28042.GU90_07380	2.817e-62	226.0	COG0667@1|root,COG0667@2|Bacteria,2GJ4R@201174|Actinobacteria,4E0A8@85010|Pseudonocardiales	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	-	ko:K18471	ko00640,map00640	-	R10718	RC00739	ko00000,ko00001,ko01000	-	-	-	Aldo_ket_red
CMS1_k127_17379_12	1121127.JAFA01000010_gene3933	2.018e-06	52.0	COG1024@1|root,COG1024@2|Bacteria,1PJ4R@1224|Proteobacteria,2VKXI@28216|Betaproteobacteria,1K6J0@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS1_k127_17379_9	1128421.JAGA01000002_gene1580	4.201e-48	188.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	GT87,PMT_2
CMS1_k127_17379_1	1120972.AUMH01000017_gene774	4.571e-157	500.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
CMS1_k127_17379_6	909943.HIMB100_00003080	7.344e-60	217.0	COG1082@1|root,COG1082@2|Bacteria,1R8NU@1224|Proteobacteria	1224|Proteobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS1_k127_1776653_4	926549.KI421517_gene3816	1.036e-09	63.0	COG0318@1|root,COG0318@2|Bacteria,4NEXK@976|Bacteroidetes,47KUG@768503|Cytophagia	976|Bacteroidetes	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	menE	-	6.2.1.26	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04030	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C
CMS1_k127_1776653_1	1131269.AQVV01000005_gene388	5.93e-59	225.0	COG3639@1|root,COG3639@2|Bacteria	2|Bacteria	P	organic phosphonate transmembrane transporter activity	phnE	-	-	ko:K02042	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	BPD_transp_1
CMS1_k127_1776653_0	1307761.L21SP2_1483	8.127e-101	334.0	COG3638@1|root,COG3638@2|Bacteria,2J6UW@203691|Spirochaetes	203691|Spirochaetes	P	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system	phnC	-	3.6.3.28	ko:K02041	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.9	-	-	ABC_tran
CMS1_k127_1776653_2	459349.CLOAM1518	1.39e-48	190.0	COG3221@1|root,COG3221@2|Bacteria,2NPZY@2323|unclassified Bacteria	2|Bacteria	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	phnD	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
CMS1_k127_1776653_5	670487.Ocepr_0856	1.364e-09	70.0	COG1652@1|root,COG1652@2|Bacteria	2|Bacteria	S	positive regulation of growth rate	-	-	-	-	-	-	-	-	-	-	-	-	LysM
CMS1_k127_1783686_0	926569.ANT_25700	5.297e-173	591.0	COG0265@1|root,COG0642@1|root,COG2203@1|root,COG0265@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,2G7SE@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
CMS1_k127_1783686_1	693661.Arcve_0350	2.217e-25	111.0	COG2405@1|root,arCOG00719@2157|Archaea,2XXKY@28890|Euryarchaeota	28890|Euryarchaeota	V	nucleic acid-binding protein contains PIN domain	-	-	-	ko:K07066	-	-	-	-	ko00000	-	-	-	-
CMS1_k127_1783686_2	1169161.KB897732_gene68	2.63e-05	52.0	COG1653@1|root,COG1653@2|Bacteria,2GP9H@201174|Actinobacteria	201174|Actinobacteria	G	Extracellular solute-binding protein	-	-	-	ko:K17326	ko02010,map02010	M00619	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.21	-	-	SBP_bac_1
CMS1_k127_1789211_1	1217718.ALOU01000031_gene1606	1.873e-14	89.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2VKH1@28216|Betaproteobacteria,1JZT2@119060|Burkholderiaceae	28216|Betaproteobacteria	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc,TPR_4,zinc_ribbon_2
CMS1_k127_1789211_0	1128421.JAGA01000003_gene3678	1.435e-150	522.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2NQCZ@2323|unclassified Bacteria	2|Bacteria	K	NB-ARC domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_22,BTAD,NB-ARC,TPR_10,TPR_12,TPR_8,Trans_reg_C
CMS1_k127_1789211_2	1449346.JQMO01000002_gene1234	1.966e-09	67.0	COG5485@1|root,COG5485@2|Bacteria,2GJYB@201174|Actinobacteria,2M62J@2063|Kitasatospora	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
CMS1_k127_1798492_1	926560.KE387023_gene3263	5.119e-112	380.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,1WM5I@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12
CMS1_k127_1798492_2	1132441.KI519455_gene3675	3.184e-95	323.0	COG0111@1|root,COG0111@2|Bacteria	2|Bacteria	EH	4-phosphoerythronate dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
CMS1_k127_1798492_3	1120950.KB892788_gene38	1.314e-91	309.0	COG3618@1|root,COG3618@2|Bacteria,2IB8W@201174|Actinobacteria	201174|Actinobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CMS1_k127_1798492_0	1121861.KB899921_gene2969	1.712e-146	474.0	COG4948@1|root,COG4948@2|Bacteria,1MW5B@1224|Proteobacteria,2UNXP@28211|Alphaproteobacteria,2JQXX@204441|Rhodospirillales	204441|Rhodospirillales	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
CMS1_k127_1798492_4	1303692.SFUL_690	1.693e-07	59.0	COG2936@1|root,COG2936@2|Bacteria,2GK8B@201174|Actinobacteria	201174|Actinobacteria	IQ	Peptidase S15	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
CMS1_k127_1798734_2	880072.Desac_2946	9.484e-59	217.0	COG0457@1|root,COG0457@2|Bacteria,1N5M0@1224|Proteobacteria,42U23@68525|delta/epsilon subdivisions,2WQ2H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_8
CMS1_k127_1798734_0	13035.Dacsa_1676	4.736e-194	621.0	COG3044@1|root,COG3044@2|Bacteria,1G21U@1117|Cyanobacteria	1117|Cyanobacteria	S	ATPase of the ABC class	-	-	-	-	-	-	-	-	-	-	-	-	ABC_ATPase
CMS1_k127_1798734_3	573370.DMR_15440	1.435e-43	180.0	COG4585@1|root,COG4585@2|Bacteria,1PG7K@1224|Proteobacteria,439XZ@68525|delta/epsilon subdivisions,2X1V5@28221|Deltaproteobacteria,2MA1M@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
CMS1_k127_1798734_1	926566.Terro_3063	8.81e-59	211.0	COG2197@1|root,COG2197@2|Bacteria,3Y6T2@57723|Acidobacteria,2JMQ5@204432|Acidobacteriia	204432|Acidobacteriia	T	PFAM Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS1_k127_1798734_5	331113.SNE_A07690	6.806e-07	59.0	COG0507@1|root,COG0507@2|Bacteria,2JFJU@204428|Chlamydiae	204428|Chlamydiae	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	-	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
CMS1_k127_1798734_6	926569.ANT_20480	5.494e-05	51.0	2ESS5@1|root,33KAI@2|Bacteria,2G7C4@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1798734_7	1147.D082_22920	6.551e-05	49.0	COG4980@1|root,COG4980@2|Bacteria,1G7T1@1117|Cyanobacteria,1H5S4@1142|Synechocystis	1117|Cyanobacteria	S	YtxH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
CMS1_k127_1798867_0	1487953.JMKF01000075_gene3761	1.979e-117	392.0	COG2124@1|root,COG2124@2|Bacteria,1G3SX@1117|Cyanobacteria,1HE9Q@1150|Oscillatoriales	1117|Cyanobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
CMS1_k127_1798867_3	470704.XP_007754828.1	1.144e-10	71.0	COG0500@1|root,KOG1269@2759|Eukaryota,38FGK@33154|Opisthokonta,3NYCG@4751|Fungi,3QX15@4890|Ascomycota,20SQ0@147545|Eurotiomycetes	4751|Fungi	I	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
CMS1_k127_1798867_1	926569.ANT_15720	1.167e-65	237.0	COG0535@1|root,COG0535@2|Bacteria,2G5XT@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Radical SAM domain protein	-	-	-	ko:K22227	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
CMS1_k127_1802629_2	383372.Rcas_0265	1.086e-59	234.0	COG0596@1|root,COG0596@2|Bacteria,2G6Y2@200795|Chloroflexi	200795|Chloroflexi	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
CMS1_k127_1802629_1	485913.Krac_2379	4.645e-98	336.0	COG0642@1|root,COG2205@2|Bacteria,2G5YT@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
CMS1_k127_1802629_0	1382306.JNIM01000001_gene2511	3.476e-99	328.0	COG0745@1|root,COG0745@2|Bacteria,2G652@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_1802629_3	1380394.JADL01000014_gene149	1.197e-37	144.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TR7Q@28211|Alphaproteobacteria,2JQAV@204441|Rhodospirillales	204441|Rhodospirillales	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
CMS1_k127_1804683_1	272134.KB731324_gene5907	4.348e-127	413.0	COG0436@1|root,COG0436@2|Bacteria,1GC70@1117|Cyanobacteria,1HF16@1150|Oscillatoriales	1117|Cyanobacteria	E	Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
CMS1_k127_1804683_2	383372.Rcas_3068	3.476e-100	334.0	COG1355@1|root,COG1355@2|Bacteria,2G6V0@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the MEMO1 family	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,Memo
CMS1_k127_1804683_0	383372.Rcas_2213	2.553e-173	549.0	COG1180@1|root,COG1180@2|Bacteria,2G6B2@200795|Chloroflexi,3750G@32061|Chloroflexia	32061|Chloroflexia	O	PFAM Radical SAM domain protein	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Radical_SAM
CMS1_k127_1806032_0	1128427.KB904821_gene4266	1.441e-111	375.0	COG1249@1|root,COG1249@2|Bacteria,1G198@1117|Cyanobacteria,1H7PH@1150|Oscillatoriales	1117|Cyanobacteria	C	Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
CMS1_k127_1806032_2	533247.CRD_02060	1.429e-43	161.0	COG2343@1|root,COG2343@2|Bacteria,1G7U6@1117|Cyanobacteria,1HP52@1161|Nostocales	1117|Cyanobacteria	S	Domain of unknown function (DUF427)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
CMS1_k127_1806032_3	485913.Krac_5293	1.007e-19	97.0	COG0563@1|root,COG0563@2|Bacteria	2|Bacteria	F	adenylate kinase activity	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AAA_18,ADK,SKI
CMS1_k127_1806032_1	1267535.KB906767_gene4790	2.625e-63	227.0	COG5285@1|root,COG5285@2|Bacteria,3Y7AJ@57723|Acidobacteria	57723|Acidobacteria	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
CMS1_k127_1806032_4	1499967.BAYZ01000054_gene4831	9.923e-07	55.0	COG2442@1|root,COG2442@2|Bacteria,2NRYZ@2323|unclassified Bacteria	1499967.BAYZ01000054_gene4831|-	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_180630_2	448385.sce7173	1.841e-16	86.0	COG1566@1|root,COG1566@2|Bacteria,1Q1MT@1224|Proteobacteria,437CC@68525|delta/epsilon subdivisions,2X2HX@28221|Deltaproteobacteria,2YUXQ@29|Myxococcales	28221|Deltaproteobacteria	V	HlyD family secretion protein	-	-	-	ko:K03543	-	M00701	-	-	ko00000,ko00002,ko02000	8.A.1.1	-	-	Biotin_lipoyl_2,HlyD_3
CMS1_k127_180630_0	1254432.SCE1572_41910	1.35e-296	936.0	COG2274@1|root,COG3271@1|root,COG2274@2|Bacteria,COG3271@2|Bacteria,1R2T0@1224|Proteobacteria,43BXM@68525|delta/epsilon subdivisions,2X78E@28221|Deltaproteobacteria,2YUMW@29|Myxococcales	28221|Deltaproteobacteria	V	Peptidase C39 family	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_tran,Peptidase_C39
CMS1_k127_180630_1	1116472.MGMO_8c00120	1.679e-197	640.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,1RMUR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation	-	-	-	ko:K06147,ko:K18893	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS1_k127_1807728_5	1205680.CAKO01000029_gene5156	1.058e-10	63.0	COG1173@1|root,COG1173@2|Bacteria,1MW3R@1224|Proteobacteria,2TUCW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EP	ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
CMS1_k127_1807728_6	330214.NIDE2528	3.632e-05	53.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_1,Cupin_2
CMS1_k127_1807728_4	420324.KI912002_gene8515	3.63e-56	209.0	COG0673@1|root,COG0673@2|Bacteria,1R4NJ@1224|Proteobacteria,2U4PN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	1.1.1.18,1.1.1.369	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	-	R01183,R09951	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA
CMS1_k127_1807728_3	35754.JNYJ01000024_gene9026	1.218e-56	210.0	COG1175@1|root,COG1175@2|Bacteria,2GM6N@201174|Actinobacteria,4DC5D@85008|Micromonosporales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025,ko:K10228	ko02010,map02010	M00200,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.5	-	-	BPD_transp_1
CMS1_k127_1807728_2	1380763.BG53_15665	1.118e-66	236.0	COG0395@1|root,COG0395@2|Bacteria,1TRXW@1239|Firmicutes,4H9KX@91061|Bacilli,274NX@186822|Paenibacillaceae	91061|Bacilli	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_1807728_1	309803.CTN_1296	4.363e-95	323.0	COG3842@1|root,COG3842@2|Bacteria,2GC81@200918|Thermotogae	200918|Thermotogae	P	ABC transporter	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE
CMS1_k127_1807728_0	368408.Tpen_1165	1.939e-98	333.0	COG3839@1|root,arCOG00175@2157|Archaea,2XPUC@28889|Crenarchaeota	28889|Crenarchaeota	G	PFAM ABC transporter related	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
CMS1_k127_1808140_1	926550.CLDAP_39920	5.99e-113	387.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	DUF1929,F5_F8_type_C,Glyco_hyd_65N_2,Glyco_hydro_18,He_PIG,PA14,RCC1,SLH
CMS1_k127_1808140_2	926550.CLDAP_39920	1.019e-95	351.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	DUF1929,F5_F8_type_C,Glyco_hyd_65N_2,Glyco_hydro_18,He_PIG,PA14,RCC1,SLH
CMS1_k127_1808140_6	1150399.AQYK01000002_gene3209	3.64e-63	248.0	COG3291@1|root,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria,4FKX3@85023|Microbacteriaceae	201174|Actinobacteria	G	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	wcoG	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,PKD
CMS1_k127_1808140_8	485913.Krac_12187	1.632e-31	132.0	COG0745@1|root,COG0745@2|Bacteria	485913.Krac_12187|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1808140_11	926550.CLDAP_05830	1.348e-06	61.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	2.7.11.1,3.4.21.107,3.5.1.28	ko:K01448,ko:K04771,ko:K08884	ko01503,ko02020,map01503,map02020	M00727,M00728	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01001,ko01002,ko01011,ko03036,ko03110	-	-	-	SH3_3
CMS1_k127_1808140_9	926569.ANT_06190	4.903e-16	80.0	COG2835@1|root,COG2835@2|Bacteria	2|Bacteria	EG	tetraacyldisaccharide 4'-kinase activity	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Methyltransf_11,Methyltransf_25,Trm112p
CMS1_k127_1808140_3	357808.RoseRS_1669	5.732e-68	263.0	COG0515@1|root,COG1470@1|root,COG1716@1|root,COG0515@2|Bacteria,COG1470@2|Bacteria,COG1716@2|Bacteria,2G805@200795|Chloroflexi	200795|Chloroflexi	T	Serine/Threonine protein kinases, catalytic domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	FHA,Pkinase
CMS1_k127_1808140_7	865937.Gilli_1964	1.196e-59	237.0	COG3291@1|root,COG5295@1|root,COG3291@2|Bacteria,COG5295@2|Bacteria,4NF6Q@976|Bacteroidetes,1I12N@117743|Flavobacteriia,2P7RA@244698|Gillisia	976|Bacteroidetes	UW	candidate b-glycosidase, glycoside hydrolase family 8 protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_3_3,M60-like_N,NosD,Peptidase_M60
CMS1_k127_1808140_5	1267535.KB906767_gene669	3.849e-65	230.0	COG1215@1|root,COG1215@2|Bacteria,3Y9FH@57723|Acidobacteria,2JP7S@204432|Acidobacteriia	204432|Acidobacteriia	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS1_k127_1808140_4	765420.OSCT_1682	1.048e-67	237.0	COG3222@1|root,COG3222@2|Bacteria	2|Bacteria	S	Uncharacterized protein conserved in bacteria (DUF2064)	-	-	-	ko:K09931	-	-	-	-	ko00000	-	-	-	DUF2064
CMS1_k127_1808140_0	1121335.Clst_2416	6.848e-251	780.0	COG0362@1|root,COG0362@2|Bacteria,1TP4I@1239|Firmicutes,248YA@186801|Clostridia	186801|Clostridia	H	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
CMS1_k127_1815061_1	525904.Tter_1801	7.773e-152	486.0	COG4608@1|root,COG4608@2|Bacteria,2NQH4@2323|unclassified Bacteria	2|Bacteria	P	Oligopeptide/dipeptide transporter, C-terminal region	gsiA_8	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
CMS1_k127_1815061_2	383372.Rcas_2451	1.067e-129	423.0	COG0444@1|root,COG0444@2|Bacteria,2G893@200795|Chloroflexi	200795|Chloroflexi	P	TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
CMS1_k127_1815061_4	515635.Dtur_1706	1.807e-118	392.0	COG1173@1|root,COG1173@2|Bacteria	2|Bacteria	P	ABC-type dipeptide oligopeptide nickel transport systems, permease components	oppC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
CMS1_k127_1815061_5	525904.Tter_1804	7.292e-113	372.0	COG0601@1|root,COG0601@2|Bacteria,2NQBI@2323|unclassified Bacteria	2|Bacteria	U	Binding-protein-dependent transport system inner membrane component	oppB	-	2.4.2.7	ko:K00759,ko:K02033	ko00230,ko01100,ko02024,map00230,map01100,map02024	M00239	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko00002,ko01000,ko02000,ko04147	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_1815061_0	1120950.KB892750_gene6884	4.708e-167	549.0	COG0747@1|root,COG0747@2|Bacteria,2GMV3@201174|Actinobacteria	2|Bacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_1815061_3	1173028.ANKO01000250_gene2370	1.295e-128	426.0	COG0477@1|root,COG2814@2|Bacteria,1GQ8C@1117|Cyanobacteria,1HH9P@1150|Oscillatoriales	1117|Cyanobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_1815061_6	118166.JH976537_gene1151	1.227e-49	179.0	COG1764@1|root,COG1764@2|Bacteria,1G767@1117|Cyanobacteria,1HH0Y@1150|Oscillatoriales	1117|Cyanobacteria	O	OsmC-like protein	-	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
CMS1_k127_1816100_2	479434.Sthe_2125	2.573e-80	283.0	COG1721@1|root,COG1721@2|Bacteria,2G6Y7@200795|Chloroflexi,27YYN@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CMS1_k127_1816100_3	1121104.AQXH01000006_gene2318	6.103e-72	252.0	COG1235@1|root,COG1235@2|Bacteria,4NGB4@976|Bacteroidetes,1IWBX@117747|Sphingobacteriia	976|Bacteroidetes	S	Beta-lactamase superfamily domain	-	-	-	ko:K06136	-	-	-	-	ko00000	-	-	-	Lactamase_B_2
CMS1_k127_1816100_4	1521187.JPIM01000101_gene3499	2.882e-22	101.0	COG0664@1|root,COG0664@2|Bacteria,2GBTI@200795|Chloroflexi,375RB@32061|Chloroflexia	32061|Chloroflexia	T	PFAM cyclic nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
CMS1_k127_1816100_5	324602.Caur_1383	5.915e-22	106.0	COG0745@1|root,COG0784@1|root,COG2203@1|root,COG4191@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,2G7Y4@200795|Chloroflexi,374VX@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA,PAS_4,Response_reg
CMS1_k127_1816100_1	324602.Caur_3272	1.376e-105	357.0	COG2733@1|root,COG2733@2|Bacteria	2|Bacteria	M	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF445
CMS1_k127_1816100_0	926550.CLDAP_37840	8.046e-171	546.0	COG0541@1|root,COG0541@2|Bacteria,2G627@200795|Chloroflexi	200795|Chloroflexi	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
CMS1_k127_1816100_6	316274.Haur_4621	2.853e-21	95.0	COG0228@1|root,COG0228@2|Bacteria,2G7A3@200795|Chloroflexi,377I8@32061|Chloroflexia	32061|Chloroflexia	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
CMS1_k127_1821960_1	1048339.KB913029_gene4207	1.116e-73	255.0	COG0601@1|root,COG0601@2|Bacteria,2GK0Z@201174|Actinobacteria,4ETSF@85013|Frankiales	201174|Actinobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_1821960_0	391037.Sare_1661	2.961e-108	369.0	COG0747@1|root,COG0747@2|Bacteria,2GJ4B@201174|Actinobacteria,4D8PG@85008|Micromonosporales	201174|Actinobacteria	E	extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_1821960_2	1894.JOER01000072_gene7835	1.979e-18	91.0	2EI4I@1|root,33BVW@2|Bacteria,2IQR6@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1822475_4	525904.Tter_2197	1.756e-39	162.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_1822475_1	926550.CLDAP_29190	3.484e-72	263.0	COG1316@1|root,COG1316@2|Bacteria,2G6PZ@200795|Chloroflexi	200795|Chloroflexi	K	TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
CMS1_k127_1822475_0	45351.EDO31424	2.035e-89	302.0	COG0434@1|root,2QUBS@2759|Eukaryota,38EZC@33154|Opisthokonta,3BES3@33208|Metazoa	33208|Metazoa	S	protein F13E9.13, mitochondrial-like	-	-	-	ko:K06971	-	-	-	-	ko00000	-	-	-	BtpA
CMS1_k127_1822475_3	224325.AF_1753	3.301e-57	210.0	COG2267@1|root,arCOG01650@2157|Archaea,2XYG5@28890|Euryarchaeota	28890|Euryarchaeota	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
CMS1_k127_1822475_2	1157490.EL26_16720	1.97e-58	216.0	COG3359@1|root,COG3359@2|Bacteria,1TQQU@1239|Firmicutes,4HDMU@91061|Bacilli,279RH@186823|Alicyclobacillaceae	91061|Bacilli	L	RNase_H superfamily	yprB	-	-	ko:K07502	-	-	-	-	ko00000	-	-	-	RNase_H_2
CMS1_k127_1822497_1	1454004.AW11_00528	2.151e-49	194.0	COG0843@1|root,COG0843@2|Bacteria,1QJ23@1224|Proteobacteria,2VKFW@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome C and Quinol oxidase polypeptide I	-	-	-	-	-	-	-	-	-	-	-	-	COX1
CMS1_k127_1822497_0	1128421.JAGA01000001_gene2279	4.351e-57	210.0	COG0109@1|root,COG0109@2|Bacteria,2NPBW@2323|unclassified Bacteria	2|Bacteria	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
CMS1_k127_1824233_2	502025.Hoch_6548	1.362e-64	252.0	COG0745@1|root,COG4251@1|root,COG0745@2|Bacteria,COG4251@2|Bacteria,1QVDV@1224|Proteobacteria,43CYW@68525|delta/epsilon subdivisions,2X872@28221|Deltaproteobacteria,2Z18H@29|Myxococcales	1224|Proteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GerE,HATPase_c,HisKA,PAS_4,Response_reg,SpoIIE
CMS1_k127_1824233_1	1499967.BAYZ01000083_gene1027	8.024e-72	274.0	COG0840@1|root,COG4251@1|root,COG0840@2|Bacteria,COG4251@2|Bacteria	2|Bacteria	T	photoreceptor activity	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,MCPsignal
CMS1_k127_1824233_5	1267533.KB906737_gene1715	1.379e-07	58.0	COG2197@1|root,COG2197@2|Bacteria,3Y4DR@57723|Acidobacteria,2JJ2N@204432|Acidobacteriia	204432|Acidobacteriia	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS1_k127_1824233_0	926550.CLDAP_08440	3.6e-81	276.0	COG2197@1|root,COG2197@2|Bacteria,2G6T1@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS1_k127_1824233_4	926550.CLDAP_08450	1.557e-54	212.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G96Q@200795|Chloroflexi	200795|Chloroflexi	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS,PAS_9
CMS1_k127_1824233_3	1499967.BAYZ01000175_gene5624	2.034e-57	221.0	COG0642@1|root,COG0745@1|root,COG3437@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3437@2|Bacteria	2|Bacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HATPase_c,HisKA,PAS,PAS_4,Response_reg
CMS1_k127_1824233_6	485917.Phep_0107	0.0001212	48.0	COG1361@1|root,COG3405@1|root,COG4719@1|root,COG4932@1|root,COG1361@2|Bacteria,COG3405@2|Bacteria,COG4719@2|Bacteria,COG4932@2|Bacteria,4NMB8@976|Bacteroidetes,1IQMS@117747|Sphingobacteriia	976|Bacteroidetes	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11,He_PIG,SdrD_B
CMS1_k127_1830099_5	926569.ANT_26470	6.835e-52	195.0	COG2848@1|root,COG2848@2|Bacteria,2G6HQ@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterised ACR (DUF711)	-	-	-	ko:K09157	-	-	-	-	ko00000	-	-	-	DUF711
CMS1_k127_1830099_0	357808.RoseRS_1617	6.08e-216	678.0	COG1004@1|root,COG1004@2|Bacteria,2G62F@200795|Chloroflexi,375IW@32061|Chloroflexia	32061|Chloroflexia	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
CMS1_k127_1830099_1	867845.KI911784_gene2339	2.295e-151	489.0	COG1232@1|root,COG1232@2|Bacteria,2G5VN@200795|Chloroflexi,375DN@32061|Chloroflexia	32061|Chloroflexia	H	PFAM amine oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
CMS1_k127_1830099_3	1521187.JPIM01000047_gene134	2.012e-111	369.0	COG0392@1|root,COG0392@2|Bacteria,2G5KF@200795|Chloroflexi,374YY@32061|Chloroflexia	32061|Chloroflexia	S	PFAM conserved	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
CMS1_k127_1830099_8	926569.ANT_29030	6.869e-20	92.0	2EAGR@1|root,334K0@2|Bacteria,2G730@200795|Chloroflexi	200795|Chloroflexi	S	PFAM zinc finger, SWIM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SWIM
CMS1_k127_1830099_6	926569.ANT_01450	6.465e-46	171.0	COG2236@1|root,COG2236@2|Bacteria,2G6Y5@200795|Chloroflexi	200795|Chloroflexi	F	Phosphoribosyl transferase domain	-	-	-	ko:K07101	-	-	-	-	ko00000	-	-	-	Pribosyltran
CMS1_k127_1830099_2	926550.CLDAP_17900	6.003e-126	424.0	COG2812@1|root,COG2812@2|Bacteria,2G5PK@200795|Chloroflexi	200795|Chloroflexi	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
CMS1_k127_1830099_7	697284.ERIC2_c38920	4.629e-28	117.0	COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,4HKH3@91061|Bacilli,26Y4X@186822|Paenibacillaceae	91061|Bacilli	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	yaaK	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
CMS1_k127_1830099_4	1382356.JQMP01000003_gene2082	7.283e-81	273.0	COG0353@1|root,COG0353@2|Bacteria,2G6CT@200795|Chloroflexi,27XUN@189775|Thermomicrobia	189775|Thermomicrobia	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
CMS1_k127_1833342_1	1128421.JAGA01000003_gene3523	8.829e-90	323.0	COG0318@1|root,COG0318@2|Bacteria,2NR5F@2323|unclassified Bacteria	2|Bacteria	IQ	PFAM AMP-dependent synthetase and ligase	MA20_41400	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
CMS1_k127_1833342_0	1128421.JAGA01000003_gene3524	2.325e-99	333.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
CMS1_k127_1833342_3	324602.Caur_0478	2.431e-43	172.0	COG1277@1|root,COG1277@2|Bacteria,2G9YA@200795|Chloroflexi,37791@32061|Chloroflexia	32061|Chloroflexia	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
CMS1_k127_1833342_2	765420.OSCT_1965	3.724e-57	220.0	COG5022@1|root,COG5022@2|Bacteria,2GBHX@200795|Chloroflexi,37800@32061|Chloroflexia	32061|Chloroflexia	Z	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1833342_4	383372.Rcas_3818	4.933e-06	49.0	COG0714@1|root,COG0714@2|Bacteria,2GACN@200795|Chloroflexi,375BZ@32061|Chloroflexia	32061|Chloroflexia	S	PFAM ATPase associated with various cellular activities, AAA_3	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS1_k127_183398_0	316274.Haur_0218	2.096e-233	737.0	COG1132@1|root,COG1132@2|Bacteria,2G7QN@200795|Chloroflexi,374U2@32061|Chloroflexia	200795|Chloroflexi	V	PFAM ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
CMS1_k127_183398_1	926550.CLDAP_23290	1.996e-212	675.0	COG1132@1|root,COG1132@2|Bacteria,2G7J5@200795|Chloroflexi	200795|Chloroflexi	V	ABC transporter, transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS1_k127_183398_2	1499967.BAYZ01000005_gene5436	1.793e-07	59.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,2NQY2@2323|unclassified Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT,PMT_2,TPR_19
CMS1_k127_183644_3	266117.Rxyl_0427	3.868e-33	133.0	COG5486@1|root,COG5486@2|Bacteria,2IAYZ@201174|Actinobacteria,4CTJ6@84995|Rubrobacteria	84995|Rubrobacteria	S	Predicted metal-binding integral membrane protein (DUF2182)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2182
CMS1_k127_183644_1	445961.IW15_21765	4.489e-131	431.0	COG3391@1|root,COG3391@2|Bacteria,4PFTK@976|Bacteroidetes,1IGN2@117743|Flavobacteriia,3ZRC3@59732|Chryseobacterium	976|Bacteroidetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_183644_2	1071679.BG57_07675	1.758e-71	246.0	COG5588@1|root,COG5588@2|Bacteria,1MWK3@1224|Proteobacteria,2VMAI@28216|Betaproteobacteria,1JZMB@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1326
CMS1_k127_183644_0	383372.Rcas_3701	1.769e-144	492.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GAAG@200795|Chloroflexi,374S4@32061|Chloroflexia	32061|Chloroflexia	K	transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,TPR_12,Trans_reg_C
CMS1_k127_1844576_3	1128421.JAGA01000003_gene3678	1.292e-67	253.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2NQCZ@2323|unclassified Bacteria	2|Bacteria	K	NB-ARC domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_22,BTAD,NB-ARC,TPR_10,TPR_12,TPR_8,Trans_reg_C
CMS1_k127_1844576_2	1382306.JNIM01000001_gene514	2.318e-72	267.0	COG0515@1|root,COG0515@2|Bacteria,2G8NP@200795|Chloroflexi	200795|Chloroflexi	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DZR,Pkinase
CMS1_k127_1844576_1	583355.Caka_1842	4.795e-91	308.0	COG1208@1|root,COG1208@2|Bacteria,46UYH@74201|Verrucomicrobia,3K75K@414999|Opitutae	414999|Opitutae	JM	MobA-like NTP transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3
CMS1_k127_1844576_0	278963.ATWD01000002_gene473	3.93e-149	480.0	COG2334@1|root,COG2334@2|Bacteria	2|Bacteria	S	homoserine kinase activity	mdsC	-	2.7.1.162,2.7.1.39	ko:K02204,ko:K13059	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771,R08962	RC00002,RC00017,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APH
CMS1_k127_1861493_3	926550.CLDAP_39750	2.536e-66	254.0	COG3463@1|root,COG3463@2|Bacteria,2G8G9@200795|Chloroflexi	200795|Chloroflexi	S	Predicted membrane protein (DUF2079)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2079
CMS1_k127_1861493_5	748449.Halha_2371	3.61e-19	93.0	COG2445@1|root,COG2445@2|Bacteria,1VF8K@1239|Firmicutes,24QTN@186801|Clostridia	186801|Clostridia	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
CMS1_k127_1861493_8	760568.Desku_1710	0.0001992	49.0	COG1669@1|root,COG1669@2|Bacteria,1VFQR@1239|Firmicutes,24SC6@186801|Clostridia	186801|Clostridia	L	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
CMS1_k127_1861493_7	1144313.PMI10_02306	1.114e-08	67.0	COG1196@1|root,COG1388@1|root,COG1196@2|Bacteria,COG1388@2|Bacteria,4PAPW@976|Bacteroidetes,1ICM6@117743|Flavobacteriia,2NT4P@237|Flavobacterium	976|Bacteroidetes	DM	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
CMS1_k127_1861493_2	926550.CLDAP_31220	1.132e-91	323.0	COG5617@1|root,COG5617@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	PTPS_related
CMS1_k127_1861493_1	926550.CLDAP_03240	7.012e-131	441.0	COG1287@1|root,COG1287@2|Bacteria	2|Bacteria	S	oligosaccharyl transferase activity	-	-	2.4.99.18	ko:K07151	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00072	R04216,R05976	RC00005,RC00482	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT66	-	-
CMS1_k127_1861493_4	926550.CLDAP_03230	1.492e-43	179.0	COG5617@1|root,COG5617@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	PTPS_related,YfhO
CMS1_k127_1861493_0	868595.Desca_1359	1.011e-261	835.0	COG1615@1|root,COG1615@2|Bacteria,1TQHM@1239|Firmicutes,248PM@186801|Clostridia,260EY@186807|Peptococcaceae	186801|Clostridia	S	PFAM Uncharacterised protein family UPF0182	-	-	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
CMS1_k127_1861493_6	234267.Acid_4940	3.793e-13	78.0	COG1409@1|root,COG1657@1|root,COG4412@1|root,COG1409@2|Bacteria,COG1657@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	ko:K14647,ko:K20276,ko:K21449	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko02000,ko03110	1.B.40.2	-	-	CARDB,Peptidase_M30
CMS1_k127_1868078_1	96561.Dole_0790	3.16e-53	212.0	COG3292@1|root,COG3292@2|Bacteria,1QU1S@1224|Proteobacteria,42WTY@68525|delta/epsilon subdivisions,2WSR0@28221|Deltaproteobacteria,2MNQR@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PFAM Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,PKD,Peptidase_C13,Reg_prop
CMS1_k127_1868078_3	635013.TherJR_1318	2.215e-27	118.0	COG3030@1|root,COG3030@2|Bacteria,1VF5Y@1239|Firmicutes,24NG5@186801|Clostridia,265YP@186807|Peptococcaceae	186801|Clostridia	S	FxsA cytoplasmic membrane protein	-	-	-	ko:K07113	-	-	-	-	ko00000	-	-	-	FxsA
CMS1_k127_1868078_2	163908.KB235896_gene1691	2.121e-36	142.0	COG1487@1|root,COG1487@2|Bacteria,1G7I9@1117|Cyanobacteria,1HNQE@1161|Nostocales	1117|Cyanobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
CMS1_k127_1868078_0	485913.Krac_2933	2.558e-63	223.0	COG3372@1|root,COG3372@2|Bacteria	2|Bacteria	S	COGs COG3372 conserved	-	-	-	ko:K09744	-	-	-	-	ko00000	-	-	-	DUF790
CMS1_k127_1868735_0	749414.SBI_01679	3.774e-186	598.0	COG3533@1|root,COG3533@2|Bacteria,2GM60@201174|Actinobacteria	201174|Actinobacteria	G	protein conserved in bacteria	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
CMS1_k127_1868735_1	926550.CLDAP_33180	6.632e-111	368.0	COG1609@1|root,COG1609@2|Bacteria,2G8QM@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
CMS1_k127_1869826_3	1183438.GKIL_3285	5.408e-68	235.0	COG0505@1|root,COG0505@2|Bacteria,1G19V@1117|Cyanobacteria	1117|Cyanobacteria	F	Belongs to the CarA family	carA	GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
CMS1_k127_1869826_1	177437.HRM2_47760	0.0	1256.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,42MGK@68525|delta/epsilon subdivisions,2WJQH@28221|Deltaproteobacteria,2MHQD@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Carbamoyl-phosphate synthetase large chain oligomerisation	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
CMS1_k127_1869826_2	398512.JQKC01000033_gene5009	7.07e-250	779.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,2490X@186801|Clostridia,3WGBX@541000|Ruminococcaceae	186801|Clostridia	C	glutamate synthase	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
CMS1_k127_1869826_0	903818.KI912268_gene806	0.0	2306.0	COG0067@1|root,COG0069@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,3Y2JQ@57723|Acidobacteria	57723|Acidobacteria	E	glutamate synthase alpha subunit	-	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
CMS1_k127_1869826_4	1297617.JPJD01000012_gene843	5.211e-26	111.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1TQ0B@1239|Firmicutes,248IB@186801|Clostridia,268NF@186813|unclassified Clostridiales	186801|Clostridia	E	Glutamate synthase central domain	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
CMS1_k127_187347_11	1122132.AQYH01000005_gene443	1.068e-12	74.0	COG1312@1|root,COG1312@2|Bacteria,1MWYD@1224|Proteobacteria,2U42Y@28211|Alphaproteobacteria,4BD7S@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	D-mannonate dehydratase (UxuA)	-	-	4.2.1.8	ko:K01686	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	UxuA
CMS1_k127_187347_7	243231.GSU3451	5.239e-72	254.0	COG1073@1|root,COG1073@2|Bacteria,1RIWI@1224|Proteobacteria,42TGK@68525|delta/epsilon subdivisions,2WRBS@28221|Deltaproteobacteria,43VRI@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
CMS1_k127_187347_5	215803.DB30_1101	9.385e-84	291.0	2DFQT@1|root,32U5Y@2|Bacteria,1MZ5S@1224|Proteobacteria,42UEJ@68525|delta/epsilon subdivisions,2WQUF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_187347_4	926550.CLDAP_29060	1.702e-103	347.0	COG1562@1|root,COG1562@2|Bacteria,2G6KD@200795|Chloroflexi	200795|Chloroflexi	I	PFAM Squalene phytoene synthase	crtB	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
CMS1_k127_187347_0	926569.ANT_13470	5.952e-253	790.0	COG1233@1|root,COG1233@2|Bacteria,2G5ZA@200795|Chloroflexi	200795|Chloroflexi	C	PFAM amine oxidase	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
CMS1_k127_187347_9	649638.Trad_2243	3.821e-42	166.0	COG0204@1|root,COG2324@1|root,COG0204@2|Bacteria,COG2324@2|Bacteria,1WI4U@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	TIGRFAM lycopene cyclase domain	-	-	5.5.1.19	ko:K22502	ko00906,map00906	-	R03824,R05341	RC01004	ko00000,ko00001,ko01000	-	-	-	Caroten_synth
CMS1_k127_187347_2	926550.CLDAP_20410	4.817e-140	463.0	COG2124@1|root,COG2124@2|Bacteria,2G623@200795|Chloroflexi	2|Bacteria	C	PFAM Cytochrome P450	cyp139A3	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0008150,GO:0008152,GO:0008202,GO:0016125,GO:0016491,GO:0030312,GO:0044238,GO:0044464,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901615	-	-	-	-	-	-	-	-	-	-	p450
CMS1_k127_187347_3	926569.ANT_00800	2.041e-114	380.0	COG1215@1|root,COG1215@2|Bacteria,2G6RJ@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K14597	ko00906,map00906	-	R07544,R07546	RC00262	ko00000,ko00001	-	-	-	Glycos_transf_2
CMS1_k127_187347_8	926550.CLDAP_20460	1.256e-44	169.0	COG0344@1|root,COG0344@2|Bacteria,2G8ZF@200795|Chloroflexi	200795|Chloroflexi	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	-	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
CMS1_k127_187347_6	867845.KI911784_gene3657	9.665e-81	275.0	COG0302@1|root,COG0302@2|Bacteria,2G6VZ@200795|Chloroflexi,375HB@32061|Chloroflexia	32061|Chloroflexia	H	PFAM GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
CMS1_k127_187347_1	383372.Rcas_4411	3.747e-141	462.0	COG0415@1|root,COG0415@2|Bacteria,2G5WD@200795|Chloroflexi,375BT@32061|Chloroflexia	32061|Chloroflexia	L	PFAM DNA photolyase, FAD-binding	-	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
CMS1_k127_187347_10	1499967.BAYZ01000156_gene551	1.051e-38	148.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	1.11.1.15	ko:K03386,ko:K03564,ko:K16922	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	AhpC-TSA,Redoxin
CMS1_k127_188203_1	1173028.ANKO01000127_gene4126	8.481e-237	752.0	COG0745@1|root,COG2114@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,COG5002@2|Bacteria,1G2RJ@1117|Cyanobacteria,1H9PS@1150|Oscillatoriales	1117|Cyanobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,HATPase_c,HisKA,PAS_4,Response_reg
CMS1_k127_188203_0	469383.Cwoe_0640	5.074e-321	1003.0	COG2133@1|root,COG2133@2|Bacteria,2IB3Z@201174|Actinobacteria	201174|Actinobacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_188203_20	926569.ANT_19040	3.279e-12	70.0	2EUFH@1|root,31CAS@2|Bacteria,2G9NZ@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_188203_15	203124.Tery_1681	7.807e-27	124.0	COG2755@1|root,COG2755@2|Bacteria,1G060@1117|Cyanobacteria,1H9JP@1150|Oscillatoriales	1117|Cyanobacteria	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL
CMS1_k127_188203_12	926550.CLDAP_29940	5.449e-30	134.0	COG4942@1|root,COG4942@2|Bacteria,2G960@200795|Chloroflexi	200795|Chloroflexi	D	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_188203_2	926569.ANT_25100	7.429e-210	670.0	COG3276@1|root,COG3276@2|Bacteria,2G5JX@200795|Chloroflexi	200795|Chloroflexi	J	Selenocysteine-specific translation elongation factor	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
CMS1_k127_188203_10	1403819.BATR01000181_gene6184	3.814e-50	184.0	COG0622@1|root,COG0622@2|Bacteria,46XK7@74201|Verrucomicrobia,2IW4A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
CMS1_k127_188203_7	1499967.BAYZ01000009_gene5348	5.519e-75	257.0	COG1428@1|root,COG1428@2|Bacteria,2NR23@2323|unclassified Bacteria	2|Bacteria	F	Deoxynucleoside kinase	dck	-	-	-	-	-	-	-	-	-	-	-	dNK
CMS1_k127_188203_16	292459.STH2796	2.569e-22	109.0	COG1694@1|root,COG1694@2|Bacteria,1UJAZ@1239|Firmicutes	1239|Firmicutes	S	MazG nucleotide pyrophosphohydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	MazG
CMS1_k127_188203_8	1128421.JAGA01000003_gene3268	8.413e-63	229.0	COG1428@1|root,COG1428@2|Bacteria,2NPEH@2323|unclassified Bacteria	2|Bacteria	F	Deoxynucleoside kinase	dgk	-	2.7.1.113	ko:K15518	ko00230,map00230	-	R01967	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	HPPK,dNK
CMS1_k127_188203_14	459495.SPLC1_S205710	4.778e-28	117.0	2C1SS@1|root,32YN6@2|Bacteria,1G9HK@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_188203_17	1173028.ANKO01000017_gene97	2.753e-21	95.0	2E90H@1|root,3339X@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_188203_9	926550.CLDAP_23630	3.409e-52	192.0	COG1595@1|root,COG1595@2|Bacteria,2G6T5@200795|Chloroflexi	200795|Chloroflexi	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_188203_13	926569.ANT_13160	1.902e-28	130.0	COG1664@1|root,COG1664@2|Bacteria,2G7EZ@200795|Chloroflexi	200795|Chloroflexi	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
CMS1_k127_188203_6	1385514.N782_16435	1.079e-92	314.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4HBB9@91061|Bacilli,2Y8V6@289201|Pontibacillus	91061|Bacilli	U	ABC transporter permease	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1,OppC_N
CMS1_k127_188203_5	118166.JH976537_gene4019	2.7e-110	366.0	COG0601@1|root,COG0601@2|Bacteria,1G01A@1117|Cyanobacteria,1HA01@1150|Oscillatoriales	1117|Cyanobacteria	P	'ABC-type dipeptide oligopeptide nickel transport	-	-	-	ko:K02033,ko:K15581,ko:K15585	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439,M00440	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
CMS1_k127_188203_4	670487.Ocepr_0879	1.508e-131	438.0	COG0747@1|root,COG0747@2|Bacteria,1WIYQ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	PFAM Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_188203_22	1463921.JODF01000058_gene1798	9.16e-09	63.0	COG0454@1|root,COG0456@2|Bacteria,2H48U@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,NUDIX
CMS1_k127_188203_3	926550.CLDAP_14920	3.122e-152	491.0	COG0006@1|root,COG0006@2|Bacteria,2G7X6@200795|Chloroflexi	200795|Chloroflexi	E	Metallopeptidase family M24	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M24
CMS1_k127_188203_21	1382306.JNIM01000001_gene2485	4.361e-09	60.0	298EI@1|root,2ZVJR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_188203_18	324602.Caur_2678	4.714e-18	93.0	2EDBT@1|root,33781@2|Bacteria,2G8Y5@200795|Chloroflexi,376V2@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_188203_11	314265.R2601_04438	1.293e-41	174.0	COG2304@1|root,COG2931@1|root,COG2304@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
CMS1_k127_1886243_5	118168.MC7420_4140	4.137e-54	197.0	2DBFE@1|root,2Z8XI@2|Bacteria,1G3YU@1117|Cyanobacteria,1HAI0@1150|Oscillatoriales	1117|Cyanobacteria	S	Plasmid pRiA4b ORF-3-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3
CMS1_k127_1886243_2	316274.Haur_4945	1.906e-146	482.0	COG0488@1|root,COG0488@2|Bacteria,2G5VD@200795|Chloroflexi,3752Q@32061|Chloroflexia	2|Bacteria	S	PFAM ABC transporter related	yjjK	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
CMS1_k127_1886243_6	1382306.JNIM01000001_gene1397	2.318e-45	169.0	COG1259@1|root,COG1259@2|Bacteria,2G6P6@200795|Chloroflexi	200795|Chloroflexi	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
CMS1_k127_1886243_1	926550.CLDAP_11960	9.291e-184	584.0	COG0305@1|root,COG0305@2|Bacteria,2G64D@200795|Chloroflexi	200795|Chloroflexi	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
CMS1_k127_1886243_8	926550.CLDAP_11970	1.177e-41	162.0	COG3935@1|root,COG3935@2|Bacteria,2G6W5@200795|Chloroflexi	200795|Chloroflexi	L	TIGRFAM primosome, DnaD subunit	-	-	-	-	-	-	-	-	-	-	-	-	DnaB_2
CMS1_k127_1886243_3	926550.CLDAP_11980	4.385e-142	465.0	COG1484@1|root,COG1484@2|Bacteria,2G65F@200795|Chloroflexi	200795|Chloroflexi	L	PFAM IstB domain protein ATP-binding protein	-	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
CMS1_k127_1886243_4	926550.CLDAP_01500	4.766e-73	261.0	COG0628@1|root,COG0628@2|Bacteria,2G6TV@200795|Chloroflexi	200795|Chloroflexi	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
CMS1_k127_1886243_0	926569.ANT_04140	0.0	1114.0	COG0542@1|root,COG0542@2|Bacteria,2G62D@200795|Chloroflexi	200795|Chloroflexi	O	ATPase associated with various cellular activities, AAA_5	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
CMS1_k127_1886243_7	373994.Riv7116_4321	6.876e-43	162.0	COG0545@1|root,COG0545@2|Bacteria,1G5T1@1117|Cyanobacteria,1HJH3@1161|Nostocales	1117|Cyanobacteria	O	Peptidyl-prolyl cis-trans isomerase	fkpA	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
CMS1_k127_1888844_6	796940.HMPREF9628_01521	2.612e-10	64.0	COG0438@1|root,COG0438@2|Bacteria,1V9PT@1239|Firmicutes,24MGK@186801|Clostridia	186801|Clostridia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
CMS1_k127_1888844_9	324602.Caur_0983	4.986e-07	62.0	2EU3R@1|root,33MKI@2|Bacteria,2G9PI@200795|Chloroflexi,375XX@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1888844_0	886293.Sinac_2262	5.632e-76	273.0	COG2265@1|root,COG2265@2|Bacteria	2|Bacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rsmJ	-	2.1.1.11,2.1.1.242	ko:K03428,ko:K07003,ko:K15984	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R04237	RC00003,RC00460	ko00000,ko00001,ko01000,ko03009	-	-	-	Methyltransf_21,Methyltransf_25,Methyltransf_31,SAM_MT,rRNA_methylase
CMS1_k127_1888844_7	324602.Caur_0983	2.169e-09	64.0	2EU3R@1|root,33MKI@2|Bacteria,2G9PI@200795|Chloroflexi,375XX@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1888844_2	1346791.M529_15510	4.347e-39	161.0	COG2227@1|root,COG2227@2|Bacteria,1N8GE@1224|Proteobacteria,2UJ9K@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
CMS1_k127_1888844_1	1499967.BAYZ01000193_gene3917	2.545e-74	263.0	COG0438@1|root,COG0438@2|Bacteria,2NQE7@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
CMS1_k127_1888844_4	221288.JH992901_gene5376	4.154e-36	153.0	COG0438@1|root,COG0438@2|Bacteria,1G3U9@1117|Cyanobacteria	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CMS1_k127_1888844_10	187303.BN69_2986	1.442e-06	59.0	COG2227@1|root,COG2227@2|Bacteria,1NN3B@1224|Proteobacteria,2TSKA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Methyltransferase	-	-	-	ko:K15257	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_23,Methyltransf_9
CMS1_k127_1888844_8	765420.OSCT_0854	5.622e-09	67.0	COG0438@1|root,COG0438@2|Bacteria,2GBKE@200795|Chloroflexi,3781F@32061|Chloroflexia	32061|Chloroflexia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
CMS1_k127_1888844_3	1041930.Mtc_0616	6.746e-37	154.0	COG0438@1|root,arCOG01410@2157|Archaea	2157|Archaea	M	Glycosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS1_k127_1888844_5	1128421.JAGA01000002_gene1120	1.611e-28	126.0	COG1216@1|root,COG1216@2|Bacteria,2NPQ4@2323|unclassified Bacteria	2|Bacteria	J	Glycosyltransferase like family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_1,Glycos_transf_2,TPR_16,TPR_19
CMS1_k127_1894316_1	926554.KI912675_gene2128	1.49e-215	679.0	COG2407@1|root,COG2407@2|Bacteria	2|Bacteria	G	Converts the aldose L-fucose into the corresponding ketose L-fuculose	-	-	5.3.1.4	ko:K01804	ko00040,ko01100,map00040,map01100	-	R01761	RC00516	ko00000,ko00001,ko01000	-	-	-	Arabinose_Isome,Fucose_iso_C
CMS1_k127_1894316_4	665571.STHERM_c08700	2.426e-56	214.0	COG0287@1|root,COG0287@2|Bacteria	2|Bacteria	E	prephenate dehydrogenase (NADP+) activity	tyrA	-	1.3.1.12	ko:K00210	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,PDH
CMS1_k127_1894316_5	3659.XP_004163714.1	3.245e-12	79.0	COG0077@1|root,KOG2797@2759|Eukaryota,37I2F@33090|Viridiplantae,3G9NF@35493|Streptophyta,4JN90@91835|fabids	35493|Streptophyta	E	Converts the prephenate produced from the shikimate- chorismate pathway into phenylalanine	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009314,GO:0009416,GO:0009507,GO:0009536,GO:0009628,GO:0009637,GO:0009642,GO:0009645,GO:0009987,GO:0010244,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0019438,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0047769,GO:0050896,GO:0071704,GO:0080167,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223	4.2.1.51,4.2.1.91	ko:K05359	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	PDT
CMS1_k127_1894316_0	1047013.AQSP01000122_gene2229	1.372e-245	771.0	COG2192@1|root,COG2192@2|Bacteria,2NNRR@2323|unclassified Bacteria	2|Bacteria	O	Carbamoyltransferase C-terminus	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
CMS1_k127_1894316_7	1047013.AQSP01000122_gene2228	4.9e-08	57.0	294GU@1|root,2ZRWK@2|Bacteria,2NRXQ@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1894316_8	504472.Slin_4252	1.655e-05	49.0	2EGPU@1|root,33AFZ@2|Bacteria,4NXYH@976|Bacteroidetes,47S90@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1894316_6	1313421.JHBV01000043_gene3036	4.702e-12	78.0	COG0388@1|root,COG0388@2|Bacteria,4NEAQ@976|Bacteroidetes,1IPV0@117747|Sphingobacteriia	976|Bacteroidetes	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	ramA_2	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,CN_hydrolase
CMS1_k127_1894316_3	118163.Ple7327_1229	3.889e-70	243.0	COG1280@1|root,COG1280@2|Bacteria,1G8NE@1117|Cyanobacteria,3VKUI@52604|Pleurocapsales	1117|Cyanobacteria	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
CMS1_k127_1894316_2	1122223.KB890700_gene1977	5.413e-85	290.0	COG0452@1|root,COG0452@2|Bacteria,1WIH0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
CMS1_k127_1898374_1	593117.TGAM_1114	0.0002148	51.0	COG5305@1|root,arCOG05830@2157|Archaea,2Y1FG@28890|Euryarchaeota,242ME@183968|Thermococci	183968|Thermococci	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS1_k127_1898374_0	383372.Rcas_4131	1.227e-05	56.0	COG1807@1|root,COG1807@2|Bacteria,2GBKP@200795|Chloroflexi,377PV@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase family 39	-	-	-	-	-	-	-	-	-	-	-	-	PMT
CMS1_k127_1907521_2	926550.CLDAP_38070	4.398e-126	417.0	COG0773@1|root,COG0773@2|Bacteria,2G5J4@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS1_k127_1907521_4	926569.ANT_23420	6.406e-84	288.0	COG0812@1|root,COG0812@2|Bacteria,2G6H3@200795|Chloroflexi	200795|Chloroflexi	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
CMS1_k127_1907521_3	479434.Sthe_1990	1.196e-125	412.0	COG1181@1|root,COG1181@2|Bacteria,2G5RS@200795|Chloroflexi,27XTQ@189775|Thermomicrobia	189775|Thermomicrobia	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
CMS1_k127_1907521_6	402881.Plav_2425	2.317e-06	58.0	COG1589@1|root,COG1589@2|Bacteria,1MY1Q@1224|Proteobacteria,2TQPU@28211|Alphaproteobacteria,1JPB0@119043|Rhodobiaceae	28211|Alphaproteobacteria	D	POTRA domain, FtsQ-type	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
CMS1_k127_1907521_1	1382306.JNIM01000001_gene41	3.175e-135	441.0	COG0849@1|root,COG0849@2|Bacteria,2G5V5@200795|Chloroflexi	200795|Chloroflexi	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
CMS1_k127_1907521_0	926569.ANT_23460	1.37e-142	460.0	COG0206@1|root,COG0206@2|Bacteria,2G5V2@200795|Chloroflexi	200795|Chloroflexi	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	-	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
CMS1_k127_1907521_5	255470.cbdbA286	1.14e-44	168.0	COG1327@1|root,COG1327@2|Bacteria,2G6QI@200795|Chloroflexi,34CXD@301297|Dehalococcoidia	301297|Dehalococcoidia	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
CMS1_k127_1909185_4	479434.Sthe_0723	1.23e-43	173.0	COG0477@1|root,COG2814@2|Bacteria,2G6MT@200795|Chloroflexi,27YU9@189775|Thermomicrobia	189775|Thermomicrobia	EGP	Major Facilitator Superfamily	-	-	-	ko:K08223	-	-	-	-	ko00000,ko02000	2.A.1.35	-	-	MFS_1
CMS1_k127_1909185_5	485913.Krac_2087	9.07e-41	159.0	COG0491@1|root,COG0491@2|Bacteria,2G78X@200795|Chloroflexi	200795|Chloroflexi	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS1_k127_1909185_0	469371.Tbis_2599	2.2e-235	738.0	COG1032@1|root,COG1032@2|Bacteria,2HW71@201174|Actinobacteria,4E7P4@85010|Pseudonocardiales	201174|Actinobacteria	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
CMS1_k127_1909185_6	608538.HTH_1380	1.714e-23	118.0	COG3210@1|root,COG3227@1|root,COG3210@2|Bacteria,COG3227@2|Bacteria	2|Bacteria	E	Zinc metalloprotease (Elastase)	-	-	3.2.1.18,3.4.11.10	ko:K01186,ko:K05994,ko:K21449	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko01002,ko02000,ko02042	1.B.40.2	GH33	-	Beta_helix,PKD,Peptidase_S74,fn3
CMS1_k127_1909185_3	1313421.JHBV01000029_gene1950	1.496e-76	291.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PKD,SprB
CMS1_k127_1909185_2	479434.Sthe_2890	9.944e-201	640.0	COG0146@1|root,COG0146@2|Bacteria,2G644@200795|Chloroflexi,27XUU@189775|Thermomicrobia	2|Bacteria	EQ	PFAM Hydantoinase B oxoprolinase	MA20_04180	-	3.5.2.14,3.5.2.9	ko:K01469,ko:K01474	ko00330,ko00480,ko01100,map00330,map00480,map01100	-	R00251,R03187	RC00553,RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
CMS1_k127_1909185_1	479434.Sthe_2889	1.834e-206	662.0	COG0145@1|root,COG0145@2|Bacteria,2G5KZ@200795|Chloroflexi,27XUM@189775|Thermomicrobia	2|Bacteria	EQ	Hydantoinaseoxoprolinase domain protein	oplaH	-	3.5.2.14,3.5.2.9	ko:K01469,ko:K01473	ko00330,ko00480,ko01100,map00330,map00480,map01100	-	R00251,R03187	RC00553,RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
CMS1_k127_1910661_3	331678.Cphamn1_0872	7.77e-52	185.0	COG2361@1|root,COG2361@2|Bacteria	2|Bacteria	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
CMS1_k127_1910661_6	136993.KB900626_gene727	3.326e-19	90.0	COG1669@1|root,COG1669@2|Bacteria,1NABR@1224|Proteobacteria	1224|Proteobacteria	L	DNA polymerase beta domain protein region	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
CMS1_k127_1910661_2	1382306.JNIM01000001_gene1559	1.721e-64	233.0	COG1609@1|root,COG1609@2|Bacteria,2G6CQ@200795|Chloroflexi	200795|Chloroflexi	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K03435	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
CMS1_k127_1910661_0	525904.Tter_2323	7.963e-114	371.0	COG0684@1|root,COG0684@2|Bacteria	2|Bacteria	H	ribonuclease inhibitor activity	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
CMS1_k127_1910661_4	926569.ANT_04040	8.199e-42	171.0	COG1653@1|root,COG1653@2|Bacteria,2G82H@200795|Chloroflexi	200795|Chloroflexi	G	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K02027,ko:K10188	ko02010,map02010	M00199,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.4	-	-	SBP_bac_1,SBP_bac_8
CMS1_k127_1910661_1	66692.ABC0317	3.135e-96	323.0	COG1175@1|root,COG1175@2|Bacteria,1TPTZ@1239|Firmicutes,4HB63@91061|Bacilli,1ZAQ5@1386|Bacillus	91061|Bacilli	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_1910661_5	926560.KE387023_gene2425	3.007e-40	156.0	COG0395@1|root,COG0395@2|Bacteria,1WMDN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_1913666_2	358681.BBR47_49270	5.491e-23	105.0	28MT6@1|root,2ZB1H@2|Bacteria,1V021@1239|Firmicutes,4HDZB@91061|Bacilli,26WU4@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1913666_1	1089553.Tph_c21870	5.623e-42	162.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
CMS1_k127_1913666_3	525904.Tter_2712	2.596e-17	89.0	COG4283@1|root,COG4283@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1706)	M1-431	-	-	-	-	-	-	-	-	-	-	-	DUF1706
CMS1_k127_1913666_0	926550.CLDAP_26330	7.835e-60	229.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,PPC,Peptidase_M6
CMS1_k127_1914539_3	926550.CLDAP_33690	2.417e-77	278.0	COG3307@1|root,COG3307@2|Bacteria,2G6TE@200795|Chloroflexi	200795|Chloroflexi	M	PFAM O-antigen polymerase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
CMS1_k127_1914539_5	926550.CLDAP_33680	2.494e-28	120.0	COG2246@1|root,COG2246@2|Bacteria,2G7BJ@200795|Chloroflexi	200795|Chloroflexi	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
CMS1_k127_1914539_0	1128421.JAGA01000002_gene1655	6.26e-103	346.0	COG0438@1|root,COG0438@2|Bacteria,2NR3F@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS1_k127_1914539_7	520999.PROVALCAL_02338	0.0005217	52.0	COG2223@1|root,COG2223@2|Bacteria,1MXAA@1224|Proteobacteria,1RMZZ@1236|Gammaproteobacteria,3Z7GM@586|Providencia	1236|Gammaproteobacteria	P	Psort location CytoplasmicMembrane, score 10.00	fsr	GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0033554,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071944	-	ko:K08223	-	-	-	-	ko00000,ko02000	2.A.1.35	-	-	MFS_1
CMS1_k127_1914539_4	179408.Osc7112_6251	1.377e-66	231.0	COG0645@1|root,COG0645@2|Bacteria	2|Bacteria	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_18,AAA_33,CPT
CMS1_k127_1914539_6	1173020.Cha6605_1551	2.613e-10	61.0	COG0617@1|root,COG0617@2|Bacteria	2|Bacteria	J	CTP:tRNA cytidylyltransferase activity	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974,ko:K19545	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko01504,ko03016,ko03019	-	-	-	Aminoglyc_resit,HD,PolyA_pol,PolyA_pol_RNAbd
CMS1_k127_1921410_0	926550.CLDAP_34110	3.369e-61	237.0	COG1305@1|root,COG1305@2|Bacteria,2G66M@200795|Chloroflexi	200795|Chloroflexi	E	PFAM transglutaminase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
CMS1_k127_1921410_1	926550.CLDAP_34120	1.424e-57	216.0	COG1721@1|root,COG1721@2|Bacteria,2G5XH@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CMS1_k127_1923347_2	1267535.KB906767_gene1479	3.2e-143	463.0	COG0148@1|root,COG0148@2|Bacteria,3Y2IT@57723|Acidobacteria,2JI6Q@204432|Acidobacteriia	57723|Acidobacteria	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	-	-	-	-	-	-	-	-	-	-	-	-	Enolase_C,Enolase_N
CMS1_k127_1923347_7	926550.CLDAP_00150	8.618e-07	59.0	COG0664@1|root,COG0664@2|Bacteria,2G902@200795|Chloroflexi	200795|Chloroflexi	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_6,Fer4_7,cNMP_binding
CMS1_k127_1923347_4	765420.OSCT_3186	1.695e-91	326.0	COG4995@1|root,COG4995@2|Bacteria,2G8YF@200795|Chloroflexi,377C0@32061|Chloroflexia	32061|Chloroflexia	P	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,SIR2_2
CMS1_k127_1923347_5	269797.Mbar_A2862	2.891e-82	307.0	COG2319@1|root,arCOG02561@2157|Archaea,2Y41K@28890|Euryarchaeota,2NAYQ@224756|Methanomicrobia	224756|Methanomicrobia	S	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	WD40
CMS1_k127_1923347_6	671143.DAMO_1988	2.794e-44	186.0	COG1262@1|root,COG1262@2|Bacteria,2NR8C@2323|unclassified Bacteria	2|Bacteria	S	Sulfatase-modifying factor enzyme 1	-	-	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	FGE-sulfatase
CMS1_k127_1923347_8	357808.RoseRS_1432	2.986e-06	50.0	28I2M@1|root,2Z85A@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF4058)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4058
CMS1_k127_1923347_1	317936.Nos7107_2876	1.641e-163	552.0	COG4870@1|root,COG4870@2|Bacteria,1GKX6@1117|Cyanobacteria,1HQZ4@1161|Nostocales	1117|Cyanobacteria	O	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
CMS1_k127_1923347_3	272123.Anacy_2458	1.522e-115	387.0	COG4870@1|root,COG4870@2|Bacteria,1GKX6@1117|Cyanobacteria,1HQZ4@1161|Nostocales	1117|Cyanobacteria	O	Peptidase family C25	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
CMS1_k127_1923347_0	765420.OSCT_3149	1.455e-171	561.0	COG4870@1|root,COG4870@2|Bacteria	2|Bacteria	O	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,Peptidase_C1,Peptidase_C25,YkuD
CMS1_k127_1924480_6	926550.CLDAP_13520	1.008e-14	75.0	COG2128@1|root,COG2128@2|Bacteria	2|Bacteria	S	hydroperoxide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS1_k127_1924480_4	926550.CLDAP_13510	1.965e-29	121.0	COG2128@1|root,COG2128@2|Bacteria	2|Bacteria	S	hydroperoxide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS1_k127_1924480_3	926550.CLDAP_16840	3.027e-58	223.0	2EDFC@1|root,3366P@2|Bacteria,2G7IW@200795|Chloroflexi	200795|Chloroflexi	S	Helicase conserved C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C_3
CMS1_k127_1924480_5	926550.CLDAP_16820	1.379e-24	112.0	COG0789@1|root,COG0789@2|Bacteria	2|Bacteria	K	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding	-	-	3.1.21.3,5.4.99.60,5.4.99.61	ko:K01153,ko:K06042,ko:K22491	ko00860,ko01100,map00860,map01100	-	R05177,R05814	RC01292,RC01980	ko00000,ko00001,ko01000,ko02048,ko03000	-	-	-	B12-binding,B12-binding_2,EcoEI_R_C,HTH_17,Helicase_C,MerR_1,ResIII
CMS1_k127_1924480_2	926569.ANT_02860	1.735e-83	291.0	COG0349@1|root,COG0349@2|Bacteria,2G74K@200795|Chloroflexi	200795|Chloroflexi	L	3'-5' exonuclease	-	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
CMS1_k127_1924480_1	926550.CLDAP_15160	9.275e-122	399.0	COG0395@1|root,COG0395@2|Bacteria,2G8ET@200795|Chloroflexi	200795|Chloroflexi	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17236	ko02010,map02010	M00602	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.34	-	-	BPD_transp_1
CMS1_k127_1924480_0	926550.CLDAP_15150	2.743e-130	422.0	COG1175@1|root,COG1175@2|Bacteria,2G8FH@200795|Chloroflexi	200795|Chloroflexi	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17235	ko02010,map02010	M00602	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.34	-	-	BPD_transp_1
CMS1_k127_1930113_6	1499967.BAYZ01000195_gene3083	5.856e-24	102.0	COG3372@1|root,COG3372@2|Bacteria	2|Bacteria	S	COGs COG3372 conserved	-	-	-	ko:K09744	-	-	-	-	ko00000	-	-	-	DUF790
CMS1_k127_1930113_8	1284352.AOIG01000008_gene2394	1.218e-07	63.0	COG0640@1|root,COG0640@2|Bacteria,1V1HY@1239|Firmicutes,4HG51@91061|Bacilli,26RZX@186822|Paenibacillaceae	91061|Bacilli	K	ArsR family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
CMS1_k127_1930113_7	326427.Cagg_1228	1.833e-23	105.0	COG3688@1|root,COG3688@2|Bacteria,2G95S@200795|Chloroflexi,375WR@32061|Chloroflexia	32061|Chloroflexia	S	YacP-like NYN domain	-	-	-	ko:K06962	-	-	-	-	ko00000	-	-	-	NYN_YacP
CMS1_k127_1930113_5	926569.ANT_06790	1.818e-68	241.0	COG0457@1|root,COG0457@2|Bacteria,2G770@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
CMS1_k127_1930113_3	926569.ANT_06780	3.409e-85	284.0	COG2229@1|root,COG2229@2|Bacteria,2G8FZ@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM small GTP-binding protein	-	-	-	ko:K06945	-	-	-	-	ko00000	-	-	-	ATP_bind_1
CMS1_k127_1930113_4	926569.ANT_06770	2.91e-75	260.0	COG2267@1|root,COG2267@2|Bacteria,2G761@200795|Chloroflexi	200795|Chloroflexi	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CMS1_k127_1930113_0	926569.ANT_06750	6.987e-146	474.0	COG1207@1|root,COG1207@2|Bacteria,2G7KV@200795|Chloroflexi	200795|Chloroflexi	M	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
CMS1_k127_1930113_1	555079.Toce_2079	1.011e-125	412.0	COG5322@1|root,COG5322@2|Bacteria,1TSXZ@1239|Firmicutes,24992@186801|Clostridia,42EPQ@68295|Thermoanaerobacterales	186801|Clostridia	S	Shikimate quinate 5-dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Shikimate_DH
CMS1_k127_1930113_2	926569.ANT_06590	1.122e-95	322.0	COG2199@1|root,COG3706@2|Bacteria,2G85T@200795|Chloroflexi	200795|Chloroflexi	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
CMS1_k127_1935458_8	1499967.BAYZ01000171_gene5540	1.674e-08	63.0	COG5012@1|root,COG5012@2|Bacteria	2|Bacteria	T	cobalamin binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1935458_2	339670.Bamb_6423	4.138e-43	166.0	COG1011@1|root,COG1011@2|Bacteria,1MU1H@1224|Proteobacteria,2VN8N@28216|Betaproteobacteria,1K3YZ@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Haloacid dehalogenase, type II	-	-	3.8.1.2	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
CMS1_k127_1935458_5	1120960.ATXG01000001_gene612	2.51e-23	105.0	2E3U2@1|root,32YRF@2|Bacteria,2GSNJ@201174|Actinobacteria,4FSKG@85023|Microbacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1935458_9	666686.B1NLA3E_11630	0.0004585	44.0	28MFE@1|root,2ZASW@2|Bacteria,1UF9Q@1239|Firmicutes,4IN6Y@91061|Bacilli,1ZMYC@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1935458_0	575540.Isop_3045	1.598e-53	196.0	COG0457@1|root,COG0457@2|Bacteria,2IZQ0@203682|Planctomycetes	203682|Planctomycetes	S	PFAM type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
CMS1_k127_1935458_7	313624.NSP_52220	1.949e-19	100.0	COG0500@1|root,COG2226@2|Bacteria,1GREX@1117|Cyanobacteria,1HQVH@1161|Nostocales	1117|Cyanobacteria	Q	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
CMS1_k127_1935458_1	926550.CLDAP_34210	6.888e-45	168.0	COG1047@1|root,COG1047@2|Bacteria,2G744@200795|Chloroflexi	200795|Chloroflexi	G	FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K01802,ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
CMS1_k127_1935458_4	926550.CLDAP_34220	4.475e-26	110.0	COG1278@1|root,COG1278@2|Bacteria,2G7EU@200795|Chloroflexi	200795|Chloroflexi	K	'Cold-shock' DNA-binding domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
CMS1_k127_1935458_3	1173028.ANKO01000174_gene2720	1.293e-40	160.0	COG1357@1|root,COG1357@2|Bacteria,1G1UU@1117|Cyanobacteria,1HAMK@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
CMS1_k127_1939803_9	1499680.CCFE01000011_gene785	4.312e-28	121.0	COG3342@1|root,COG3342@2|Bacteria,1TS8U@1239|Firmicutes,4HBYK@91061|Bacilli,1ZCG3@1386|Bacillus	91061|Bacilli	S	Family of unknown function (DUF1028)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1028,PG_binding_2
CMS1_k127_1939803_5	926550.CLDAP_11230	1.072e-96	324.0	COG1173@1|root,COG1173@2|Bacteria,2G6HB@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
CMS1_k127_1939803_3	926550.CLDAP_11240	2.356e-113	374.0	COG0601@1|root,COG0601@2|Bacteria,2G6BV@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_1939803_1	926550.CLDAP_11250	9.72e-167	541.0	COG0747@1|root,COG0747@2|Bacteria,2G6BC@200795|Chloroflexi	200795|Chloroflexi	E	COGs COG0747 ABC-type dipeptide transport system periplasmic component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_1939803_2	1128421.JAGA01000004_gene2705	3.425e-117	392.0	COG0624@1|root,COG0624@2|Bacteria	2|Bacteria	E	succinyl-diaminopimelate desuccinylase activity	dapE	-	3.5.1.16,3.5.1.18	ko:K01436,ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R00669,R02734,R09107	RC00064,RC00090,RC00300	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
CMS1_k127_1939803_0	616991.JPOO01000003_gene652	7.757e-213	671.0	COG0370@1|root,COG0370@2|Bacteria,4NGRN@976|Bacteroidetes,1I03Y@117743|Flavobacteriia	976|Bacteroidetes	P	transporter of a GTP-driven Fe(2 ) uptake system	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
CMS1_k127_1939803_4	945713.IALB_0510	1.5e-109	360.0	COG0370@1|root,COG0370@2|Bacteria	2|Bacteria	P	ferrous iron transmembrane transporter activity	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
CMS1_k127_1939803_6	945713.IALB_0509	6.501e-83	285.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria	2|Bacteria	P	iron ion homeostasis	feoA	-	-	ko:K03322,ko:K03709,ko:K04758	-	-	-	-	ko00000,ko02000,ko03000	2.A.55.2.6,2.A.55.3	-	-	Fe_dep_repr_C,FeoA
CMS1_k127_1939803_7	720554.Clocl_2735	3.566e-76	260.0	COG4021@1|root,COG4021@2|Bacteria,1UVX1@1239|Firmicutes,24DQH@186801|Clostridia,3WGX4@541000|Ruminococcaceae	186801|Clostridia	S	Thg1 C terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Thg1,Thg1C
CMS1_k127_1942790_2	765420.OSCT_1671	5.462e-19	92.0	COG0500@1|root,COG2226@2|Bacteria,2GB34@200795|Chloroflexi,3778K@32061|Chloroflexia	32061|Chloroflexia	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS1_k127_1942790_3	1182590.BN5_01621	7.162e-15	78.0	COG0388@1|root,COG0388@2|Bacteria,1MWQG@1224|Proteobacteria,1RYY7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Nitrilase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
CMS1_k127_1942790_1	485913.Krac_2956	1.222e-78	274.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,FR47
CMS1_k127_1942790_0	590998.Celf_1230	7.808e-159	511.0	COG5297@1|root,COG5297@2|Bacteria,2GK39@201174|Actinobacteria,4F14I@85016|Cellulomonadaceae	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase family 6	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_2,Glyco_hydro_6
CMS1_k127_1943003_1	1121106.JQKB01000007_gene1070	8.347e-131	428.0	COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,2TTWK@28211|Alphaproteobacteria,2JV0E@204441|Rhodospirillales	204441|Rhodospirillales	E	Methionine synthase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1943003_0	1382306.JNIM01000001_gene1511	8.241e-302	961.0	COG0457@1|root,COG3629@1|root,COG3899@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG3899@2|Bacteria,2G871@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,TPR_12,TPR_8
CMS1_k127_1943003_6	1298863.AUEP01000008_gene1241	5.731e-54	199.0	29ZNQ@1|root,30MP9@2|Bacteria,2IJUR@201174|Actinobacteria,4DUE8@85009|Propionibacteriales	201174|Actinobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
CMS1_k127_1943003_8	1382306.JNIM01000001_gene1513	2.426e-29	125.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_3,GNAT_acetyltran
CMS1_k127_1943003_3	1461694.ATO9_21845	2.574e-88	295.0	COG0346@1|root,COG0346@2|Bacteria,1MWCV@1224|Proteobacteria,2TUY3@28211|Alphaproteobacteria,2PD6N@252301|Oceanicola	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS1_k127_1943003_10	1121935.AQXX01000096_gene2567	8.394e-24	104.0	2EGVV@1|root,33AN3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1943003_2	926560.KE387023_gene1204	5.626e-95	320.0	COG2378@1|root,COG2378@2|Bacteria,1WKYM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	WYL
CMS1_k127_1943003_4	926554.KI912640_gene1367	2.754e-76	262.0	COG1733@1|root,COG1733@2|Bacteria,1WMU2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
CMS1_k127_1943003_7	1227497.C491_11813	3.506e-46	177.0	COG0500@1|root,arCOG01783@2157|Archaea,2XWBW@28890|Euryarchaeota,23UCS@183963|Halobacteria	183963|Halobacteria	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
CMS1_k127_1943003_5	268407.PWYN_06035	1.838e-71	250.0	COG0500@1|root,COG2226@2|Bacteria,1V0UT@1239|Firmicutes,4IT1S@91061|Bacilli,2777J@186822|Paenibacillaceae	91061|Bacilli	Q	sAM-dependent methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
CMS1_k127_1943003_11	1479238.JQMZ01000001_gene1004	4.217e-05	53.0	2DVM1@1|root,33WB8@2|Bacteria,1NW7Z@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1945362_7	1185876.BN8_00573	2.065e-47	181.0	COG3485@1|root,COG3485@2|Bacteria,4PC6V@976|Bacteroidetes,47WWP@768503|Cytophagia	976|Bacteroidetes	Q	Dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Dioxygenase_C
CMS1_k127_1945362_4	996637.SGM_4940	2.454e-98	331.0	COG0395@1|root,COG0395@2|Bacteria,2GNQW@201174|Actinobacteria	201174|Actinobacteria	G	Binding-protein-dependent transport systems inner membrane component	ngcG	-	-	ko:K10202	ko02010,map02010	M00205	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.18	-	-	BPD_transp_1
CMS1_k127_1945362_6	35754.JNYJ01000060_gene2512	9.157e-75	260.0	COG1175@1|root,COG1175@2|Bacteria,2GJZD@201174|Actinobacteria,4DBF0@85008|Micromonosporales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10201	ko02010,map02010	M00205	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.18	-	-	BPD_transp_1
CMS1_k127_1945362_3	1246995.AFR_34710	4.39e-121	406.0	COG1653@1|root,COG1653@2|Bacteria,2GJM5@201174|Actinobacteria,4DB06@85008|Micromonosporales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	ngcE	-	-	ko:K10200	ko02010,map02010	M00205	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.18	-	-	SBP_bac_1,SBP_bac_8
CMS1_k127_1945362_2	1382356.JQMP01000001_gene932	1.371e-140	455.0	COG0395@1|root,COG0395@2|Bacteria,2G7QJ@200795|Chloroflexi,27Z38@189775|Thermomicrobia	189775|Thermomicrobia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_1945362_1	926550.CLDAP_34330	1.624e-146	473.0	COG1175@1|root,COG1175@2|Bacteria	2|Bacteria	P	transmembrane transport	-	-	-	ko:K02025,ko:K05814,ko:K10118,ko:K10237,ko:K10241,ko:K15771,ko:K17235,ko:K17242,ko:K17316	ko02010,map02010	M00196,M00198,M00204,M00206,M00207,M00491,M00600,M00602,M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.17,3.A.1.1.2,3.A.1.1.23,3.A.1.1.24,3.A.1.1.28,3.A.1.1.3,3.A.1.1.30,3.A.1.1.34,3.A.1.1.39	-	-	BPD_transp_1
CMS1_k127_1945362_0	309801.trd_0251	1.846e-222	700.0	COG1653@1|root,COG1653@2|Bacteria,2G891@200795|Chloroflexi,27YX0@189775|Thermomicrobia	189775|Thermomicrobia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1
CMS1_k127_1945362_5	1123023.JIAI01000001_gene7159	3.967e-93	314.0	COG2141@1|root,COG2141@2|Bacteria,2GIY3@201174|Actinobacteria,4DXE3@85010|Pseudonocardiales	201174|Actinobacteria	C	PFAM Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS1_k127_1947114_2	867845.KI911784_gene3221	6.322e-79	272.0	COG1319@1|root,COG1319@2|Bacteria,2G60Y@200795|Chloroflexi,3765V@32061|Chloroflexia	32061|Chloroflexia	C	CO dehydrogenase flavoprotein domain protein	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
CMS1_k127_1947114_0	413816.BBJP01000008_gene561	0.0	1028.0	COG1529@1|root,arCOG01167@2157|Archaea,2XSZN@28890|Euryarchaeota,23S55@183963|Halobacteria	183963|Halobacteria	C	COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
CMS1_k127_1947114_1	383372.Rcas_0843	1.934e-79	268.0	COG2080@1|root,COG2080@2|Bacteria,2G6NT@200795|Chloroflexi,3764A@32061|Chloroflexia	32061|Chloroflexia	C	2Fe-2S -binding domain protein	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
CMS1_k127_1947114_3	765420.OSCT_0125	1.365e-41	162.0	COG3170@1|root,COG3427@1|root,COG3170@2|Bacteria,COG3427@2|Bacteria,2G6U6@200795|Chloroflexi,376AP@32061|Chloroflexia	32061|Chloroflexia	NU	PFAM carbon monoxide dehydrogenase subunit G	-	-	-	ko:K09386	-	-	-	-	ko00000	-	-	-	COXG
CMS1_k127_1949034_3	1236902.ANAS01000031_gene2880	1.06e-46	172.0	COG1109@1|root,COG1208@1|root,COG1109@2|Bacteria,COG1208@2|Bacteria,2GKTE@201174|Actinobacteria,4EFSZ@85012|Streptosporangiales	201174|Actinobacteria	GJM	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	-	-	2.7.7.13,5.4.2.8	ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II,PGM_PMM_III
CMS1_k127_1949034_2	765420.OSCT_1980	1.536e-163	536.0	COG5316@1|root,COG5316@2|Bacteria,2GBUR@200795|Chloroflexi,375C5@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1949034_0	1120973.AQXL01000134_gene1536	1.209e-212	694.0	COG2352@1|root,COG2352@2|Bacteria,1TQB6@1239|Firmicutes,4HCAF@91061|Bacilli,278RF@186823|Alicyclobacillaceae	91061|Bacilli	C	Phosphoenolpyruvate carboxylase	ppc	GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
CMS1_k127_1949034_1	234267.Acid_6523	3.321e-203	658.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,3Y6FN@57723|Acidobacteria	57723|Acidobacteria	EU	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
CMS1_k127_1949619_0	886293.Sinac_5883	1.244e-170	547.0	COG3119@1|root,COG3379@1|root,COG3119@2|Bacteria,COG3379@2|Bacteria,2IYF3@203682|Planctomycetes	203682|Planctomycetes	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
CMS1_k127_1949619_1	926550.CLDAP_27890	1.26e-128	422.0	COG0438@1|root,COG0438@2|Bacteria,2G7W9@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4
CMS1_k127_1949619_2	926569.ANT_20350	6.447e-115	385.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS1_k127_1949619_3	1196322.A370_01072	0.0001018	53.0	COG1961@1|root,COG1961@2|Bacteria,1TPBH@1239|Firmicutes,25B5K@186801|Clostridia,36GE4@31979|Clostridiaceae	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
CMS1_k127_195028_2	1009370.ALO_08335	1.072e-53	198.0	COG1414@1|root,COG1414@2|Bacteria,1TRMW@1239|Firmicutes,4H40E@909932|Negativicutes	909932|Negativicutes	K	Bacterial transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
CMS1_k127_195028_3	485913.Krac_5054	3.204e-13	78.0	2C6H9@1|root,2ZQWJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_195028_1	1380391.JIAS01000011_gene4754	1.61e-154	504.0	COG5598@1|root,COG5598@2|Bacteria,1MX73@1224|Proteobacteria,2TS1M@28211|Alphaproteobacteria,2JVS6@204441|Rhodospirillales	28211|Alphaproteobacteria	H	Trimethylamine methyltransferase (MTTB)	-	-	-	-	-	-	-	-	-	-	-	-	MTTB
CMS1_k127_195028_0	1380394.JADL01000003_gene4950	2.026e-162	516.0	COG0665@1|root,COG0665@2|Bacteria,1R40G@1224|Proteobacteria,2U1VU@28211|Alphaproteobacteria,2JRIU@204441|Rhodospirillales	204441|Rhodospirillales	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
CMS1_k127_195299_3	926550.CLDAP_24710	1.816e-24	104.0	COG0647@1|root,COG0647@2|Bacteria,2G6QY@200795|Chloroflexi	200795|Chloroflexi	G	PFAM Haloacid dehalogenase domain protein hydrolase	-	-	-	ko:K02566	-	-	-	-	ko00000	-	-	-	Hydrolase_6,Hydrolase_like
CMS1_k127_195299_1	485914.Hmuk_0623	2.434e-81	286.0	COG0673@1|root,arCOG01622@2157|Archaea	2157|Archaea	L	dehydrogenases and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_195299_0	1226325.HMPREF1548_05729	4.531e-176	566.0	COG3119@1|root,COG3119@2|Bacteria,1TQEP@1239|Firmicutes,2482B@186801|Clostridia,36G0T@31979|Clostridiaceae	186801|Clostridia	P	Psort location Cytoplasmic, score 9.97	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	DUF4976,Sulfatase
CMS1_k127_1953102_1	552811.Dehly_0983	2.446e-84	290.0	COG0514@1|root,COG1205@1|root,COG0514@2|Bacteria,COG1205@2|Bacteria,2G605@200795|Chloroflexi,34CMG@301297|Dehalococcoidia	301297|Dehalococcoidia	L	Domain of unknown function (DUF1998)	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
CMS1_k127_1953102_8	1463887.KL589954_gene7191	5.464e-06	55.0	COG2318@1|root,COG2318@2|Bacteria,2GXK3@201174|Actinobacteria	201174|Actinobacteria	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
CMS1_k127_1953102_4	484770.UFO1_2541	2.903e-45	174.0	COG4589@1|root,COG4589@2|Bacteria,1TT0Q@1239|Firmicutes,4H4UZ@909932|Negativicutes	909932|Negativicutes	S	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
CMS1_k127_1953102_3	765420.OSCT_0136	1.149e-55	211.0	COG4924@1|root,COG4924@2|Bacteria,2GAPK@200795|Chloroflexi,376YN@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function C-terminus (DUF2399)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2220
CMS1_k127_1953102_0	760568.Desku_0321	8.15e-152	520.0	COG4913@1|root,COG4913@2|Bacteria,1TPVZ@1239|Firmicutes,2491E@186801|Clostridia,2630X@186807|Peptococcaceae	186801|Clostridia	S	DNA replication and repair protein RecF	-	-	-	-	-	-	-	-	-	-	-	-	AAA_29,SMC_hinge,SbcCD_C
CMS1_k127_1953102_7	760568.Desku_0320	1.25e-23	108.0	2A8HA@1|root,30XJD@2|Bacteria,1UPU3@1239|Firmicutes,25HP8@186801|Clostridia,26728@186807|Peptococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4194)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4194
CMS1_k127_1953102_2	1121430.JMLG01000002_gene1102	1.08e-55	213.0	28JJB@1|root,2Z9CE@2|Bacteria,1U6BP@1239|Firmicutes,24B0T@186801|Clostridia,261SW@186807|Peptococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1953102_5	266117.Rxyl_2026	2.63e-38	152.0	COG0220@1|root,COG0220@2|Bacteria,2GJ8R@201174|Actinobacteria	201174|Actinobacteria	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
CMS1_k127_1953102_6	926550.CLDAP_09270	7.066e-31	126.0	COG0488@1|root,COG0488@2|Bacteria,2G5VD@200795|Chloroflexi	200795|Chloroflexi	S	PFAM ABC transporter related	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
CMS1_k127_1953878_4	1122921.KB898209_gene2653	5.401e-05	46.0	2BR0X@1|root,32JYC@2|Bacteria,1U1R4@1239|Firmicutes,4IB7I@91061|Bacilli,273UA@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1953878_1	926569.ANT_14530	1.787e-54	199.0	COG2068@1|root,COG2068@2|Bacteria,2G6W9@200795|Chloroflexi	200795|Chloroflexi	S	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
CMS1_k127_1953878_0	1500304.JQKY01000015_gene1919	4.679e-78	287.0	COG0642@1|root,COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,COG4585@2|Bacteria,1R3TZ@1224|Proteobacteria,2U1UX@28211|Alphaproteobacteria,4B83E@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA_3
CMS1_k127_1953878_2	1500304.JQKY01000015_gene1918	2.973e-44	169.0	COG2197@1|root,COG2197@2|Bacteria,1R2TM@1224|Proteobacteria,2TU4S@28211|Alphaproteobacteria,4BN96@82115|Rhizobiaceae	28211|Alphaproteobacteria	KT	helix_turn_helix, Lux Regulon	MA20_20785	-	-	ko:K07684,ko:K07693	ko02020,map02020	M00471,M00479	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
CMS1_k127_1953878_3	909663.KI867150_gene1692	1.796e-22	106.0	COG2080@1|root,COG2080@2|Bacteria,1PGQD@1224|Proteobacteria,434AK@68525|delta/epsilon subdivisions,2X9WM@28221|Deltaproteobacteria,2MRQZ@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
CMS1_k127_1956821_2	1128421.JAGA01000003_gene2870	1.157e-56	201.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,2NNV6@2323|unclassified Bacteria	2|Bacteria	C	4Fe-4S dicluster domain	hmeA	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molydop_binding
CMS1_k127_1956821_1	886293.Sinac_3667	6.361e-82	277.0	COG3880@1|root,COG3880@2|Bacteria,2IYYJ@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
CMS1_k127_1956821_3	670487.Ocepr_0101	2.121e-08	64.0	COG2010@1|root,COG2010@2|Bacteria,1WIF2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
CMS1_k127_1956821_0	1382306.JNIM01000001_gene1966	1.115e-92	310.0	COG0076@1|root,COG0076@2|Bacteria,2G7N6@200795|Chloroflexi	200795|Chloroflexi	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.105,4.1.1.28,4.1.2.27	ko:K01593,ko:K01634	ko00350,ko00360,ko00380,ko00600,ko00901,ko00950,ko00965,ko01100,ko01110,ko04071,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00600,map00901,map00950,map00965,map01100,map01110,map04071,map04726,map04728,map05030,map05031,map05034	M00037,M00042,M00100	R00685,R00699,R00736,R02080,R02464,R02701,R04909,R06516	RC00264,RC00299,RC00721,RC01266	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
CMS1_k127_1957326_4	1227454.C446_00035	2.416e-110	365.0	COG4608@1|root,arCOG00184@2157|Archaea,2Y5BH@28890|Euryarchaeota,23UJ9@183963|Halobacteria	183963|Halobacteria	E	COG4608 ABC-type oligopeptide transport system, ATPase component	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,oligo_HPY
CMS1_k127_1957326_6	797114.C475_00355	2.829e-100	337.0	COG0444@1|root,arCOG00181@2157|Archaea,2XTA6@28890|Euryarchaeota,23T1F@183963|Halobacteria	183963|Halobacteria	E	COG0444 ABC-type dipeptide oligopeptide nickel transport system, ATPase component	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
CMS1_k127_1957326_5	1384049.CD29_08355	2.598e-110	364.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4HBB9@91061|Bacilli,3IVTQ@400634|Lysinibacillus	91061|Bacilli	U	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
CMS1_k127_1957326_3	1227454.C446_00050	7.164e-116	382.0	COG0601@1|root,arCOG00751@2157|Archaea,2XU87@28890|Euryarchaeota,23S7B@183963|Halobacteria	183963|Halobacteria	P	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_1957326_1	1384049.CD29_08345	6.029e-145	479.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,4HAM7@91061|Bacilli,3IWCQ@400634|Lysinibacillus	91061|Bacilli	E	ABC transporter substrate-binding protein	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_1957326_0	479434.Sthe_0274	2.38e-162	529.0	COG0146@1|root,COG0146@2|Bacteria,2G644@200795|Chloroflexi,27XUU@189775|Thermomicrobia	2|Bacteria	EQ	PFAM Hydantoinase B oxoprolinase	-	-	3.5.2.14,3.5.2.9	ko:K01469,ko:K01474	ko00330,ko00480,ko01100,map00330,map00480,map01100	-	R00251,R03187	RC00553,RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
CMS1_k127_1957326_2	330084.JNYZ01000068_gene8553	5.317e-117	387.0	COG0145@1|root,COG0145@2|Bacteria,2GIYE@201174|Actinobacteria	201174|Actinobacteria	EQ	PFAM Hydantoinase oxoprolinase	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
CMS1_k127_1958040_13	525904.Tter_0396	9.054e-08	53.0	COG2141@1|root,COG2141@2|Bacteria,2NQM2@2323|unclassified Bacteria	2|Bacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS1_k127_1958040_8	68260.JOAY01000034_gene2561	1.121e-23	111.0	28HGI@1|root,2Z7SC@2|Bacteria,2GKHQ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1958040_10	326427.Cagg_1666	1.534e-19	94.0	COG0296@1|root,COG0296@2|Bacteria,2G9SJ@200795|Chloroflexi,377QN@32061|Chloroflexia	32061|Chloroflexia	G	PFAM glycoside hydrolase family 13 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM,CBM_48
CMS1_k127_1958040_12	504728.K649_14465	4.025e-09	60.0	COG2250@1|root,COG2250@2|Bacteria,1WJYR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
CMS1_k127_1958040_11	383372.Rcas_1020	1.563e-18	89.0	COG1708@1|root,COG1708@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	ko:K07076	-	-	-	-	ko00000	-	-	-	HEPN,NTP_transf_2
CMS1_k127_1958040_9	1173028.ANKO01000017_gene129	1.377e-21	96.0	2DDDQ@1|root,2ZHMV@2|Bacteria,1GGC7@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1958040_5	406817.XNC1_2727	3.779e-55	195.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,1S3QE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	FG	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases	hinT	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019478,GO:0019752,GO:0043436,GO:0043530,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046144,GO:0046395,GO:0046416,GO:0046436,GO:0055130,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	DcpS_C,HIT
CMS1_k127_1958040_2	671143.DAMO_1182	3.172e-87	291.0	COG0717@1|root,COG0717@2|Bacteria,2NQ5G@2323|unclassified Bacteria	2|Bacteria	F	Belongs to the dCTP deaminase family	dcd	GO:0003674,GO:0003824,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
CMS1_k127_1958040_3	357808.RoseRS_2738	1.881e-75	258.0	COG0491@1|root,COG0491@2|Bacteria,2G6X9@200795|Chloroflexi,3777M@32061|Chloroflexia	32061|Chloroflexia	S	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS1_k127_1958040_7	316274.Haur_4407	2.492e-43	161.0	COG3118@1|root,COG3118@2|Bacteria,2G6U1@200795|Chloroflexi,375U0@32061|Chloroflexia	32061|Chloroflexia	O	Belongs to the thioredoxin family	-	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
CMS1_k127_1958040_1	1128421.JAGA01000002_gene1835	9.245e-88	296.0	COG0639@1|root,COG0639@2|Bacteria,2NPHT@2323|unclassified Bacteria	2|Bacteria	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
CMS1_k127_1958040_0	926550.CLDAP_30410	2.354e-97	336.0	COG3583@1|root,COG3584@1|root,COG3583@2|Bacteria,COG3584@2|Bacteria,2G8CU@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF348)	-	-	-	-	-	-	-	-	-	-	-	-	DUF348,G5
CMS1_k127_1958040_4	926569.ANT_03800	6.762e-70	246.0	COG0030@1|root,COG0030@2|Bacteria,2G6DA@200795|Chloroflexi	200795|Chloroflexi	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
CMS1_k127_1958040_6	926550.CLDAP_00920	2.752e-49	185.0	COG0741@1|root,COG1729@1|root,COG0741@2|Bacteria,COG1729@2|Bacteria,2G6NM@200795|Chloroflexi	200795|Chloroflexi	M	Lytic transglycosylase catalytic	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,TPR_16,TPR_6
CMS1_k127_1959601_3	926550.CLDAP_32480	3.789e-44	181.0	COG1807@1|root,COG1807@2|Bacteria	926550.CLDAP_32480|-	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1959601_1	479434.Sthe_2126	7.115e-117	383.0	COG0714@1|root,COG0714@2|Bacteria,2G669@200795|Chloroflexi,27YUB@189775|Thermomicrobia	189775|Thermomicrobia	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS1_k127_1959601_0	1227349.C170_25962	1.513e-220	691.0	COG1486@1|root,COG1486@2|Bacteria,1TQ9I@1239|Firmicutes,4HCGH@91061|Bacilli,26V5X@186822|Paenibacillaceae	91061|Bacilli	G	Family 4 glycosyl hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_4,Glyco_hydro_4C
CMS1_k127_1959601_2	383372.Rcas_3447	4.744e-51	191.0	COG1714@1|root,COG1714@2|Bacteria,2G7CB@200795|Chloroflexi,375N6@32061|Chloroflexia	32061|Chloroflexia	S	PFAM RDD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	RDD
CMS1_k127_1959601_4	383372.Rcas_1121	0.0003445	51.0	COG3847@1|root,COG3847@2|Bacteria,2GB1R@200795|Chloroflexi,377RD@32061|Chloroflexia	32061|Chloroflexia	U	PFAM Flp Fap pilin component	-	-	-	ko:K02651	ko04112,map04112	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	Flp_Fap
CMS1_k127_1959928_3	1122915.AUGY01000070_gene4238	2.359e-81	283.0	COG0673@1|root,COG0673@2|Bacteria,1UWP1@1239|Firmicutes,4I6SZ@91061|Bacilli,26USD@186822|Paenibacillaceae	91061|Bacilli	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_1959928_5	243090.RB6199	9.307e-66	237.0	COG0673@1|root,COG0673@2|Bacteria,2IYB5@203682|Planctomycetes	203682|Planctomycetes	S	PFAM oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_1959928_6	649349.Lbys_1653	2.123e-64	236.0	COG1162@1|root,COG1162@2|Bacteria,4NE5H@976|Bacteroidetes,47JC5@768503|Cytophagia	976|Bacteroidetes	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
CMS1_k127_1959928_9	493475.GARC_0415	1.206e-25	108.0	COG0296@1|root,COG0296@2|Bacteria,1N8WX@1224|Proteobacteria,1S8R5@1236|Gammaproteobacteria,467S6@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	Belongs to the glycosyl hydrolase 13 family	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM,CBM_48
CMS1_k127_1959928_0	1128421.JAGA01000002_gene1834	0.0	1227.0	COG0178@1|root,COG0178@2|Bacteria,2NNT3@2323|unclassified Bacteria	2|Bacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
CMS1_k127_1959928_4	56780.SYN_01003	1.331e-67	234.0	COG2110@1|root,COG2110@2|Bacteria,1RCWP@1224|Proteobacteria,42RVP@68525|delta/epsilon subdivisions,2WNCX@28221|Deltaproteobacteria,2MQI0@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Appr-1'-p processing enzyme	ymdB	-	-	-	-	-	-	-	-	-	-	-	Macro
CMS1_k127_1959928_7	926550.CLDAP_09600	4.079e-43	181.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704	-	-	-	-	-	-	-	-	-	-	Collagen
CMS1_k127_1959928_8	1230457.C476_02062	1.345e-36	149.0	COG0616@1|root,arCOG01311@2157|Archaea,2XUZ2@28890|Euryarchaeota,23V1R@183963|Halobacteria	183963|Halobacteria	O	COG0616 Periplasmic serine proteases (ClpP class)	sppA2	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
CMS1_k127_1959928_10	316274.Haur_1112	3.216e-20	104.0	COG3903@1|root,COG3903@2|Bacteria	2|Bacteria	K	ADP binding	-	-	-	ko:K16247	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,NB-ARC,TPR_12,TPR_7
CMS1_k127_1959928_1	756067.MicvaDRAFT_1841	5.575e-120	399.0	COG1672@1|root,COG1672@2|Bacteria,1G15R@1117|Cyanobacteria,1HHE7@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Archaeal ATPase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1959928_2	395493.BegalDRAFT_1285	1.779e-87	310.0	COG1672@1|root,COG1672@2|Bacteria,1N54W@1224|Proteobacteria	1224|Proteobacteria	S	PFAM Archaeal ATPase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1961280_0	926550.CLDAP_01230	1.982e-84	302.0	COG3463@1|root,COG3463@2|Bacteria,2G8G9@200795|Chloroflexi	200795|Chloroflexi	S	Predicted membrane protein (DUF2079)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2079
CMS1_k127_1961280_2	1038859.AXAU01000020_gene5421	7.249e-13	77.0	COG0125@1|root,COG0125@2|Bacteria,1N1CB@1224|Proteobacteria	1224|Proteobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1961280_1	266117.Rxyl_2653	1.283e-57	206.0	COG4297@1|root,COG4297@2|Bacteria,2H7KC@201174|Actinobacteria,4CTNE@84995|Rubrobacteria	84995|Rubrobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS1_k127_1968981_5	765698.Mesci_6254	2.955e-18	96.0	COG0834@1|root,COG0834@2|Bacteria,1N6H5@1224|Proteobacteria,2U5FP@28211|Alphaproteobacteria,43I69@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	ET	PFAM Bacterial extracellular solute-binding proteins, family 3	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
CMS1_k127_1968981_3	118161.KB235922_gene2621	1.935e-51	197.0	COG1100@1|root,COG1100@2|Bacteria,1GFDV@1117|Cyanobacteria	1117|Cyanobacteria	S	Small GTP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1968981_2	118161.KB235922_gene2620	3.866e-59	235.0	2CEWA@1|root,34BT8@2|Bacteria,1GF77@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1968981_6	1539298.JO41_07610	3.667e-18	90.0	COG3654@1|root,COG3654@2|Bacteria,2J7Z6@203691|Spirochaetes	203691|Spirochaetes	S	Death-on-curing protein	-	-	-	ko:K07341	-	-	-	-	ko00000,ko02048	-	-	-	Fic
CMS1_k127_1968981_1	1207063.P24_16857	8.137e-121	399.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TR7Q@28211|Alphaproteobacteria,2JQKF@204441|Rhodospirillales	204441|Rhodospirillales	C	III protein, CoA-transferase family	-	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
CMS1_k127_1968981_4	2903.EOD07047	5.464e-51	183.0	COG1680@1|root,2RZX2@2759|Eukaryota	2759|Eukaryota	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS1_k127_19724_6	882083.SacmaDRAFT_1921	5.224e-30	119.0	COG1150@1|root,COG1150@2|Bacteria,2H2X3@201174|Actinobacteria	201174|Actinobacteria	C	4Fe-4S dicluster domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03390	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_8
CMS1_k127_19724_3	309801.trd_0158	1.579e-59	208.0	COG2044@1|root,COG2044@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07092	-	-	-	-	ko00000	-	-	-	DrsE,DrsE_2
CMS1_k127_19724_1	309801.trd_0159	9.449e-72	245.0	COG2210@1|root,COG2210@2|Bacteria,2G77F@200795|Chloroflexi	200795|Chloroflexi	S	DsrE/DsrF/DrsH-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
CMS1_k127_19724_5	309801.trd_0160	3.482e-30	120.0	COG0425@1|root,COG0425@2|Bacteria,2G7DF@200795|Chloroflexi	200795|Chloroflexi	O	Belongs to the sulfur carrier protein TusA family	-	-	-	-	-	-	-	-	-	-	-	-	TusA
CMS1_k127_19724_7	1112274.KI911560_gene584	0.000213	46.0	COG1999@1|root,COG1999@2|Bacteria,1RHJ8@1224|Proteobacteria,2VR3M@28216|Betaproteobacteria,2KMU7@206350|Nitrosomonadales	206350|Nitrosomonadales	S	PFAM electron transport protein SCO1 SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
CMS1_k127_19724_4	1461580.CCAS010000017_gene2017	9.934e-45	169.0	COG2197@1|root,COG2197@2|Bacteria,1TRXG@1239|Firmicutes,4HCCV@91061|Bacilli,1ZDBY@1386|Bacillus	91061|Bacilli	K	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	yhcZ	-	-	ko:K02479	-	-	-	-	ko00000,ko02022	-	-	-	GerE,Response_reg
CMS1_k127_19724_2	926550.CLDAP_30530	1.047e-66	249.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	ydfH	-	2.7.13.3	ko:K07675,ko:K11623	ko02020,map02020	M00473,M00484	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF_3,HATPase_c,HisKA_3
CMS1_k127_19724_0	1379698.RBG1_1C00001G0892	1.919e-139	451.0	COG1062@1|root,COG1062@2|Bacteria	2|Bacteria	C	S-(hydroxymethyl)glutathione dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N
CMS1_k127_1972936_3	765420.OSCT_2850	1.163e-12	80.0	COG1306@1|root,COG1306@2|Bacteria,2G81Y@200795|Chloroflexi,374TT@32061|Chloroflexia	32061|Chloroflexia	M	Putative glycosyl hydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,DUF4015
CMS1_k127_1972936_0	926569.ANT_19080	1.932e-145	475.0	COG0593@1|root,COG0593@2|Bacteria,2G5W8@200795|Chloroflexi	200795|Chloroflexi	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
CMS1_k127_1972936_1	1137799.GZ78_14485	8.103e-109	364.0	COG2801@1|root,COG2801@2|Bacteria,1MVC8@1224|Proteobacteria,1RXYF@1236|Gammaproteobacteria,1XHWD@135619|Oceanospirillales	135619|Oceanospirillales	L	HTH-like domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
CMS1_k127_1972936_2	485913.Krac_9327	1.484e-74	259.0	COG3547@1|root,COG3547@2|Bacteria	2|Bacteria	L	Transposase (IS116 IS110 IS902 family)	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
CMS1_k127_1978992_6	1519464.HY22_11090	3.06e-23	115.0	COG0457@1|root,COG3947@1|root,COG0457@2|Bacteria,COG3947@2|Bacteria,1FF9Y@1090|Chlorobi	1090|Chlorobi	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD
CMS1_k127_1978992_5	765420.OSCT_2831	2.712e-29	137.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G88D@200795|Chloroflexi,374V1@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA_3
CMS1_k127_1978992_4	383372.Rcas_3420	1.841e-31	144.0	COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,2GBIX@200795|Chloroflexi,3759D@32061|Chloroflexia	32061|Chloroflexia	T	SMART PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_4
CMS1_k127_1978992_2	1121396.KB893071_gene1279	1.505e-72	255.0	COG1235@1|root,COG1235@2|Bacteria,1NW4Z@1224|Proteobacteria,42PTI@68525|delta/epsilon subdivisions,2WIWT@28221|Deltaproteobacteria,2MIKY@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
CMS1_k127_1978992_0	1313304.CALK_1537	5.152e-89	300.0	COG0467@1|root,COG0467@2|Bacteria	2|Bacteria	T	regulation of circadian rhythm	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
CMS1_k127_1978992_1	1128421.JAGA01000003_gene3053	7.554e-88	330.0	COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria,2NPIU@2323|unclassified Bacteria	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_4,PAS_8,Response_reg,dCache_1
CMS1_k127_1978992_3	926569.ANT_05570	1.843e-67	239.0	COG1816@1|root,COG1816@2|Bacteria,2G6AT@200795|Chloroflexi	200795|Chloroflexi	F	PFAM Adenosine AMP deaminase	-	-	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
CMS1_k127_1981802_1	1499967.BAYZ01000195_gene3106	3.289e-126	421.0	COG1807@1|root,COG1807@2|Bacteria,2NPZC@2323|unclassified Bacteria	2|Bacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	MA20_19960	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS1_k127_1981802_5	1206720.BAFQ01000281_gene5913	9.549e-05	48.0	COG3039@1|root,COG3039@2|Bacteria,2HW75@201174|Actinobacteria,4G565@85025|Nocardiaceae	201174|Actinobacteria	L	Transposase domain (DUF772)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
CMS1_k127_1981802_6	1347369.CCAD010000055_gene4210	0.0002801	46.0	COG3039@1|root,COG3039@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
CMS1_k127_1981802_4	1285586.H131_21347	4.383e-28	117.0	2EIF6@1|root,33C6J@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1981802_3	338963.Pcar_1138	3.34e-49	187.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	-	-	-	ko:K07257	-	-	-	-	ko00000	-	-	-	Aldo_ket_red
CMS1_k127_1981802_0	997884.HMPREF1068_01646	1.281e-126	413.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	AXE1,Abhydrolase_7,DLH,Hydrolase_4,LTD,Peptidase_S9
CMS1_k127_1983809_5	926566.Terro_0765	1.21e-18	93.0	COG0053@1|root,COG0053@2|Bacteria,3Y43E@57723|Acidobacteria,2JIIM@204432|Acidobacteriia	204432|Acidobacteriia	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
CMS1_k127_1983809_0	1128421.JAGA01000001_gene2190	3.729e-170	540.0	COG0346@1|root,COG0346@2|Bacteria,2NR6J@2323|unclassified Bacteria	2|Bacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K15975	-	-	-	-	ko00000	-	-	-	Glyoxalase
CMS1_k127_1983809_7	1232410.KI421412_gene337	1.291e-13	73.0	2C59E@1|root,2ZDAY@2|Bacteria	2|Bacteria	S	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
CMS1_k127_1983809_6	1232410.KI421412_gene336	3.155e-17	83.0	29SGJ@1|root,2ZKKB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1983809_4	926550.CLDAP_22580	3.046e-20	94.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_1,Cupin_2
CMS1_k127_1983809_8	368407.Memar_1219	0.000134	44.0	COG2361@1|root,arCOG05024@2157|Archaea	2157|Archaea	S	Protein of unknown function DUF86	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	DUF86
CMS1_k127_1983809_1	1173027.Mic7113_3552	2.184e-59	208.0	296N4@1|root,31F23@2|Bacteria,1G6IE@1117|Cyanobacteria,1HBQF@1150|Oscillatoriales	1117|Cyanobacteria	S	XisH protein	-	-	-	-	-	-	-	-	-	-	-	-	XisH
CMS1_k127_1983809_2	65393.PCC7424_4222	1.617e-44	163.0	2C9PJ@1|root,32SR6@2|Bacteria,1G8I4@1117|Cyanobacteria,3KI8T@43988|Cyanothece	1117|Cyanobacteria	S	PFAM XisI protein	-	-	-	-	-	-	-	-	-	-	-	-	XisI
CMS1_k127_1983809_3	357808.RoseRS_3017	6.677e-28	115.0	COG2886@1|root,COG2886@2|Bacteria	2|Bacteria	E	Uncharacterised protein family (UPF0175)	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31,Peptidase_M78,UPF0175
CMS1_k127_1985525_5	316274.Haur_1895	1.513e-51	190.0	COG2909@1|root,COG2909@2|Bacteria,2G7Q4@200795|Chloroflexi,3754G@32061|Chloroflexia	32061|Chloroflexia	K	ATP-dependent transcriptional regulator, MalT-like, LuxR family	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
CMS1_k127_1985525_8	33035.JPJF01000022_gene3308	1.448e-05	49.0	COG3669@1|root,COG3669@2|Bacteria,1U9XH@1239|Firmicutes,24DER@186801|Clostridia	186801|Clostridia	G	Alpha-L-fucosidase	-	-	-	-	-	-	-	-	-	-	-	-	Alpha_L_fucos
CMS1_k127_1985525_1	1303518.CCALI_00661	1.99e-83	285.0	COG5285@1|root,COG5285@2|Bacteria	2|Bacteria	Q	dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,PhyH
CMS1_k127_1985525_7	525904.Tter_1905	1.094e-14	85.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_1985525_0	1131730.BAVI_16832	4.433e-244	790.0	COG0644@1|root,COG0644@2|Bacteria,1TR0D@1239|Firmicutes,4HBWH@91061|Bacilli,1ZDCV@1386|Bacillus	91061|Bacilli	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
CMS1_k127_1985525_2	1120959.ATXF01000006_gene1934	2.487e-73	257.0	COG0395@1|root,COG0395@2|Bacteria,2GMTH@201174|Actinobacteria,4FMEN@85023|Microbacteriaceae	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_1985525_3	373903.Hore_20620	1.148e-62	228.0	COG1175@1|root,COG1175@2|Bacteria,1TRC0@1239|Firmicutes,25C59@186801|Clostridia	186801|Clostridia	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_1985525_6	406124.ACPC01000019_gene2901	7.665e-28	128.0	COG1653@1|root,COG1653@2|Bacteria,1TRIH@1239|Firmicutes,4HBRS@91061|Bacilli,1ZEWW@1386|Bacillus	91061|Bacilli	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
CMS1_k127_1985525_4	1128421.JAGA01000003_gene3718	3.766e-58	205.0	COG1132@1|root,COG1132@2|Bacteria,2NNVD@2323|unclassified Bacteria	2|Bacteria	V	ABC transporter	msbA	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS1_k127_1990208_5	926569.ANT_14880	2.809e-32	145.0	COG0823@1|root,COG0823@2|Bacteria,2G8PZ@200795|Chloroflexi	200795|Chloroflexi	U	WD40 domain protein beta Propeller	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
CMS1_k127_1990208_6	1128421.JAGA01000002_gene1700	8.328e-28	123.0	COG0500@1|root,COG2226@2|Bacteria,2NRJA@2323|unclassified Bacteria	2|Bacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
CMS1_k127_1990208_2	555088.DealDRAFT_2880	3.292e-68	242.0	COG1597@1|root,COG1597@2|Bacteria,1TQAU@1239|Firmicutes	1239|Firmicutes	I	Lipid kinase	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
CMS1_k127_1990208_3	926569.ANT_13360	5.16e-61	220.0	COG0584@1|root,COG0584@2|Bacteria,2G6YD@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
CMS1_k127_1990208_1	457425.XNR_0019	2.673e-112	375.0	COG0156@1|root,COG0156@2|Bacteria,2GISV@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,KR,PP-binding,PS-DH
CMS1_k127_1990208_7	485913.Krac_7755	2.719e-12	67.0	COG1999@1|root,COG3391@1|root,COG1999@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	wapA	-	-	ko:K07152,ko:K13730	ko05100,map05100	-	-	-	ko00000,ko00001,ko03029	-	-	-	AhpC-TSA,NHL,SCO1-SenC,Thioredoxin_8
CMS1_k127_1990208_0	479434.Sthe_1814	9.8e-135	449.0	COG1999@1|root,COG3391@1|root,COG1999@2|Bacteria,COG3391@2|Bacteria,2GAQJ@200795|Chloroflexi,27XX5@189775|Thermomicrobia	189775|Thermomicrobia	S	signal sequence binding	-	-	-	-	-	-	-	-	-	-	-	-	NHL
CMS1_k127_1990208_8	1268303.RHODMAR_1173	1.29e-10	74.0	COG0846@1|root,COG0846@2|Bacteria,2IIWC@201174|Actinobacteria	201174|Actinobacteria	K	SIR2-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SIR2_2
CMS1_k127_1990208_4	880073.Calab_3471	1.19e-43	180.0	COG1672@1|root,COG3710@1|root,COG1672@2|Bacteria,COG3710@2|Bacteria,2NR41@2323|unclassified Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	AAA_16,DUF234,LRR_4,Trans_reg_C,WG_beta_rep
CMS1_k127_1993954_3	357808.RoseRS_0410	6.134e-18	96.0	COG1807@1|root,COG1807@2|Bacteria,2GBKP@200795|Chloroflexi,377PV@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase family 39	-	-	-	-	-	-	-	-	-	-	-	-	PMT
CMS1_k127_1993954_0	926550.CLDAP_32470	1.788e-82	308.0	COG1807@1|root,COG1807@2|Bacteria,2G8DG@200795|Chloroflexi	200795|Chloroflexi	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS1_k127_1993954_1	1382306.JNIM01000001_gene959	1.397e-57	225.0	COG3463@1|root,COG3463@2|Bacteria,2G8G9@200795|Chloroflexi	200795|Chloroflexi	S	Predicted membrane protein (DUF2079)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2079
CMS1_k127_1993954_2	266117.Rxyl_1241	1.93e-19	94.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT_2
CMS1_k127_1993954_5	926550.CLDAP_04470	3.378e-12	80.0	COG1807@1|root,COG1807@2|Bacteria,2G9RZ@200795|Chloroflexi	200795|Chloroflexi	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1993954_6	926550.CLDAP_04460	3.645e-06	60.0	COG1807@1|root,COG1807@2|Bacteria,2G8YZ@200795|Chloroflexi	200795|Chloroflexi	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1993954_7	1128421.JAGA01000002_gene1731	0.00071	52.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS1_k127_1993954_4	42256.RradSPS_0544	6.774e-13	73.0	COG3463@1|root,COG3463@2|Bacteria,2GKJJ@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2079
CMS1_k127_1997754_3	671143.DAMO_0611	2.212e-26	119.0	COG1216@1|root,COG1216@2|Bacteria,2NRAF@2323|unclassified Bacteria	2|Bacteria	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	GT87
CMS1_k127_1997754_0	1183438.GKIL_3646	3.259e-122	409.0	COG1215@1|root,COG1215@2|Bacteria,1G1FP@1117|Cyanobacteria	1117|Cyanobacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
CMS1_k127_1997754_1	42256.RradSPS_2033	5.401e-92	313.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the ABC transporter superfamily	-	-	3.6.3.29	ko:K02017,ko:K02052	ko02010,ko02024,map02010,map02024	M00189,M00193	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11,3.A.1.8	-	-	ABC_tran,TOBE,TOBE_2
CMS1_k127_1997754_2	641491.DND132_0158	1.021e-29	122.0	COG0834@1|root,COG0834@2|Bacteria,1MVT6@1224|Proteobacteria,42QIN@68525|delta/epsilon subdivisions,2WKVZ@28221|Deltaproteobacteria,2M97B@213115|Desulfovibrionales	28221|Deltaproteobacteria	ET	belongs to the bacterial solute-binding protein 3 family	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
CMS1_k127_2008184_2	926569.ANT_00170	9.191e-69	240.0	COG0177@1|root,COG0177@2|Bacteria,2G6QA@200795|Chloroflexi	200795|Chloroflexi	L	FES	-	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
CMS1_k127_2008184_0	926569.ANT_05380	2.134e-147	476.0	COG1239@1|root,COG1239@2|Bacteria,2G5WJ@200795|Chloroflexi	200795|Chloroflexi	H	introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX	-	-	6.6.1.1	ko:K03404,ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	AAA_5,Mg_chelatase,VWA_2
CMS1_k127_2008184_1	926550.CLDAP_23650	4.839e-98	329.0	COG1240@1|root,COG1240@2|Bacteria,2G7UF@200795|Chloroflexi	200795|Chloroflexi	H	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
CMS1_k127_2008184_4	1041930.Mtc_1539	2.488e-11	70.0	COG0527@1|root,arCOG00861@2157|Archaea,2XTJ0@28890|Euryarchaeota,2N91C@224756|Methanomicrobia	224756|Methanomicrobia	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
CMS1_k127_2008184_3	479434.Sthe_1406	6.662e-20	98.0	COG1051@1|root,COG1051@2|Bacteria,2G77J@200795|Chloroflexi,27YGM@189775|Thermomicrobia	189775|Thermomicrobia	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS1_k127_2014368_0	926550.CLDAP_38190	0.0	1799.0	COG0085@1|root,COG0085@2|Bacteria,2G5VH@200795|Chloroflexi	200795|Chloroflexi	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
CMS1_k127_2014368_2	479436.Vpar_0845	1.596e-182	578.0	COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,4H2F2@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
CMS1_k127_2014368_1	926569.ANT_16170	9.142e-205	643.0	COG0499@1|root,COG0499@2|Bacteria,2G5X8@200795|Chloroflexi	200795|Chloroflexi	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
CMS1_k127_2014368_4	926569.ANT_16180	2.712e-93	316.0	COG0524@1|root,COG0524@2|Bacteria,2G7YR@200795|Chloroflexi	200795|Chloroflexi	G	PFAM PfkB domain protein	adoK	-	2.7.1.20	ko:K00856	ko00230,ko01100,map00230,map01100	-	R00185	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
CMS1_k127_2014368_3	926550.CLDAP_17710	1.495e-133	434.0	COG0182@1|root,COG0182@2|Bacteria,2G5Z3@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
CMS1_k127_2014368_5	203275.BFO_1126	1.744e-09	71.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,4NE4W@976|Bacteroidetes,2FM3C@200643|Bacteroidia,22X5K@171551|Porphyromonadaceae	976|Bacteroidetes	G	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_21,TPR_6,TPR_8
CMS1_k127_2023379_3	649638.Trad_1790	1.462e-41	163.0	COG4758@1|root,COG4758@2|Bacteria,1WKNW@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2154
CMS1_k127_2023379_2	84531.JMTZ01000104_gene1645	5.805e-60	224.0	COG1571@1|root,COG1571@2|Bacteria,1QVS8@1224|Proteobacteria,1T2IQ@1236|Gammaproteobacteria,1X9DX@135614|Xanthomonadales	135614|Xanthomonadales	S	tRNA wobble cytosine modification	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2023379_6	412597.AEPN01000006_gene1694	7.308e-10	70.0	COG1996@1|root,COG1996@2|Bacteria,1QV33@1224|Proteobacteria,2TW9P@28211|Alphaproteobacteria,2PVEU@265|Paracoccus	28211|Alphaproteobacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2023379_4	765420.OSCT_1005	1.16e-23	103.0	COG0296@1|root,COG0296@2|Bacteria,2G9SJ@200795|Chloroflexi,377QN@32061|Chloroflexia	32061|Chloroflexia	G	PFAM glycoside hydrolase family 13 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM,CBM_48
CMS1_k127_2023379_1	945713.IALB_2183	1.227e-101	342.0	COG0686@1|root,COG0686@2|Bacteria	2|Bacteria	E	alanine dehydrogenase activity	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
CMS1_k127_2023379_0	383372.Rcas_3773	1.467e-178	569.0	COG0427@1|root,COG0427@2|Bacteria,2G60V@200795|Chloroflexi,376DI@32061|Chloroflexia	32061|Chloroflexia	C	PFAM acetyl-CoA hydrolase transferase	-	-	3.1.2.1	ko:K01067	ko00620,map00620	-	R00227	RC00004,RC00012	ko00000,ko00001,ko01000	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
CMS1_k127_2023379_5	331869.BAL199_10457	1.574e-13	75.0	COG2128@1|root,COG2128@2|Bacteria,1N82C@1224|Proteobacteria,2TQXY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3179
CMS1_k127_2029238_3	28532.XP_010535438.1	0.0002533	49.0	COG0438@1|root,2QSX1@2759|Eukaryota,37K8E@33090|Viridiplantae,3G9YY@35493|Streptophyta,3HNWH@3699|Brassicales	35493|Streptophyta	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
CMS1_k127_2029238_1	941449.dsx2_1097	1.052e-47	185.0	COG0438@1|root,COG0438@2|Bacteria,1RFDR@1224|Proteobacteria,435R4@68525|delta/epsilon subdivisions,2X05N@28221|Deltaproteobacteria,2MAPI@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS1_k127_2029238_0	765420.OSCT_3196	4.021e-86	314.0	COG0515@1|root,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	200795|Chloroflexi	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS1_k127_2029238_2	1121946.AUAX01000001_gene2212	3.683e-05	53.0	COG3469@1|root,COG3827@1|root,COG3469@2|Bacteria,COG3827@2|Bacteria,2GJTU@201174|Actinobacteria	201174|Actinobacteria	G	alpha-galactosidase	-	-	3.2.1.14,3.2.1.4	ko:K01179,ko:K01183	ko00500,ko00520,ko01100,map00500,map00520,map01100	-	R01206,R02334,R06200,R11307,R11308	RC00467	ko00000,ko00001,ko01000	-	GH18,GH5,GH9	-	CBM_2,CBM_4_9,Calx-beta,Cellulase,Glyco_hydro_18,PE,fn3
CMS1_k127_2029989_0	1125863.JAFN01000001_gene1552	2.995e-203	656.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria	2|Bacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,Fer4_4,Fer4_7,NAD_binding_8,Pyr_redox_2
CMS1_k127_2029989_3	1121468.AUBR01000014_gene2178	7.729e-98	327.0	COG2048@1|root,COG2048@2|Bacteria,1U4JW@1239|Firmicutes,24C8P@186801|Clostridia	186801|Clostridia	C	heterodisulfide reductase	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
CMS1_k127_2029989_5	1121422.AUMW01000010_gene1059	1.086e-49	182.0	COG1150@1|root,COG1150@2|Bacteria,1V6M0@1239|Firmicutes,24M4D@186801|Clostridia,26709@186807|Peptococcaceae	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03390,ko:K16887	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_17,Fer4_8
CMS1_k127_2029989_1	290318.Cvib_0843	4.243e-177	574.0	COG1148@1|root,COG1148@2|Bacteria	2|Bacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	hdrA	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Fer4_7,Pyr_redox_2
CMS1_k127_2029989_2	1125863.JAFN01000001_gene1782	9.309e-167	537.0	COG1148@1|root,COG1148@2|Bacteria,1R99M@1224|Proteobacteria,42Q2T@68525|delta/epsilon subdivisions,2WJTB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Pyr_redox_2
CMS1_k127_2029989_4	1125863.JAFN01000001_gene1783	3.215e-83	285.0	COG2048@1|root,COG2048@2|Bacteria,1N37J@1224|Proteobacteria,42P51@68525|delta/epsilon subdivisions,2X6MI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Cysteine-rich domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG
CMS1_k127_2029989_6	477974.Daud_1252	9.921e-34	134.0	COG1150@1|root,COG1150@2|Bacteria,1V98Z@1239|Firmicutes,24JWG@186801|Clostridia,265DT@186807|Peptococcaceae	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03390	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_17,Fer4_9
CMS1_k127_2032424_2	485913.Krac_3018	3.397e-73	259.0	COG1132@1|root,COG1132@2|Bacteria,2G86M@200795|Chloroflexi	2|Bacteria	P	COGs COG1132 ABC-type multidrug transport system ATPase and permease components	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS1_k127_2032424_0	1501230.ET33_37205	1.648e-191	614.0	COG1132@1|root,COG1132@2|Bacteria,1TRCZ@1239|Firmicutes,4HCDT@91061|Bacilli,26RQU@186822|Paenibacillaceae	91061|Bacilli	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
CMS1_k127_2032424_1	533247.CRD_01036	1.032e-80	282.0	COG0265@1|root,COG0457@1|root,COG0265@2|Bacteria,COG0457@2|Bacteria,1G4J0@1117|Cyanobacteria,1HJ4A@1161|Nostocales	1117|Cyanobacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_2,TPR_8,Trypsin_2
CMS1_k127_2034102_18	933262.AXAM01000001_gene409	4.247e-08	56.0	COG5304@1|root,COG5304@2|Bacteria,1NBCZ@1224|Proteobacteria,42VY1@68525|delta/epsilon subdivisions,2WSEW@28221|Deltaproteobacteria,2MQ19@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2034102_17	660470.Theba_1010	5.142e-18	97.0	COG0738@1|root,COG0738@2|Bacteria,2GD5Y@200918|Thermotogae	200918|Thermotogae	G	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_2034102_0	1122915.AUGY01000004_gene5577	1.294e-249	783.0	COG3119@1|root,COG3119@2|Bacteria,1UDRD@1239|Firmicutes,4HD9J@91061|Bacilli,26R87@186822|Paenibacillaceae	91061|Bacilli	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CMS1_k127_2034102_2	502025.Hoch_2061	1.108e-155	505.0	COG3119@1|root,COG3119@2|Bacteria,1PG5D@1224|Proteobacteria,4358J@68525|delta/epsilon subdivisions,2WZJN@28221|Deltaproteobacteria,2Z29X@29|Myxococcales	28221|Deltaproteobacteria	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS1_k127_2034102_4	926550.CLDAP_35880	2.852e-126	413.0	COG0820@1|root,COG0820@2|Bacteria,2G5SD@200795|Chloroflexi	200795|Chloroflexi	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
CMS1_k127_2034102_13	768671.ThimaDRAFT_3043	4.955e-35	140.0	COG1193@1|root,COG1193@2|Bacteria	2|Bacteria	L	negative regulation of DNA recombination	mutS2	-	3.5.3.15	ko:K01481,ko:K07456,ko:K15577	ko00910,ko02010,ko03430,map00910,map02010,map03430	M00438	-	-	ko00000,ko00001,ko00002,ko01000,ko02000,ko03400	3.A.1.16.1,3.A.1.16.2	-	-	DUF2027,PAD,Smr
CMS1_k127_2034102_8	383372.Rcas_1610	8.35e-88	297.0	COG2253@1|root,COG2253@2|Bacteria	2|Bacteria	V	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
CMS1_k127_2034102_7	383372.Rcas_1611	1.833e-91	305.0	COG5340@1|root,COG5340@2|Bacteria	2|Bacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4,DUF559
CMS1_k127_2034102_5	357808.RoseRS_3334	1.671e-92	313.0	COG0324@1|root,COG0324@2|Bacteria,2G5S7@200795|Chloroflexi,374TE@32061|Chloroflexia	32061|Chloroflexia	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
CMS1_k127_2034102_9	1128421.JAGA01000002_gene1308	2.327e-71	247.0	COG2197@1|root,COG2197@2|Bacteria,2NPMZ@2323|unclassified Bacteria	2|Bacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS1_k127_2034102_12	1128421.JAGA01000002_gene1307	7.283e-52	205.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07777	ko02020,map02020	M00478	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,GAF_3,HATPase_c,HisKA_3,PAS,PAS_4,PAS_8
CMS1_k127_2034102_1	326427.Cagg_1059	1.241e-172	552.0	COG0477@1|root,COG2814@2|Bacteria,2G7PX@200795|Chloroflexi,3765F@32061|Chloroflexia	32061|Chloroflexia	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_2034102_3	1303518.CCALI_01626	2.315e-131	428.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	yrkH	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
CMS1_k127_2034102_10	867845.KI911784_gene1582	4.827e-71	246.0	COG0607@1|root,COG0640@1|root,COG0607@2|Bacteria,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	M1-798	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5,Rhodanese
CMS1_k127_2034102_11	525904.Tter_1300	3.337e-65	233.0	COG0382@1|root,COG0382@2|Bacteria	2|Bacteria	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	-	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
CMS1_k127_2034102_14	404589.Anae109_0701	9.642e-34	138.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
CMS1_k127_2034102_6	1122915.AUGY01000002_gene7356	3.169e-92	317.0	COG3424@1|root,COG3424@2|Bacteria,1TPUK@1239|Firmicutes,4HBHH@91061|Bacilli,26VEY@186822|Paenibacillaceae	91061|Bacilli	Q	synthase	bcsA	-	-	ko:K16167	-	-	-	-	ko00000,ko01008	-	-	-	Chal_sti_synt_C,Chal_sti_synt_N
CMS1_k127_2034102_15	717605.Theco_1774	1.433e-29	121.0	COG0644@1|root,COG0644@2|Bacteria,1U3SW@1239|Firmicutes,4HSRK@91061|Bacilli,26U60@186822|Paenibacillaceae	91061|Bacilli	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DAO,FAD_binding_3
CMS1_k127_203422_3	595460.RRSWK_01809	4.043e-24	109.0	2E2ED@1|root,32XIY@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_203422_4	1122919.KB905635_gene410	7.256e-22	109.0	COG1653@1|root,COG1653@2|Bacteria,1TRIH@1239|Firmicutes,4H9MG@91061|Bacilli,276A0@186822|Paenibacillaceae	91061|Bacilli	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1
CMS1_k127_203422_1	697281.Mahau_2566	1.058e-93	317.0	COG1175@1|root,COG1175@2|Bacteria,1TPTZ@1239|Firmicutes,2492R@186801|Clostridia,42FXR@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_203422_2	1111479.AXAR01000018_gene2543	9.633e-85	290.0	COG0395@1|root,COG0395@2|Bacteria,1UY7D@1239|Firmicutes,4HCWU@91061|Bacilli	91061|Bacilli	G	COG0395 ABC-type sugar transport system, permease component	-	-	-	ko:K02026,ko:K10242	ko02010,map02010	M00206,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.23	-	-	BPD_transp_1
CMS1_k127_203422_0	98439.AJLL01000072_gene1223	1.988e-99	327.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1146@2|Bacteria,1G2E2@1117|Cyanobacteria	1117|Cyanobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C
CMS1_k127_2039018_3	765420.OSCT_1965	1.097e-18	98.0	COG5022@1|root,COG5022@2|Bacteria,2GBHX@200795|Chloroflexi,37800@32061|Chloroflexia	32061|Chloroflexia	Z	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2039018_0	324602.Caur_3302	8.999e-131	423.0	COG2141@1|root,COG2141@2|Bacteria,2G87P@200795|Chloroflexi,377SH@32061|Chloroflexia	32061|Chloroflexia	C	Luciferase-like monooxygenase	-	-	1.14.14.5	ko:K04091	ko00920,map00920	-	R07210,R10206	RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	Bac_luciferase
CMS1_k127_2039018_1	335541.Swol_1719	2.314e-120	394.0	COG0714@1|root,COG0714@2|Bacteria,1TPKR@1239|Firmicutes,248IM@186801|Clostridia,42KK1@68298|Syntrophomonadaceae	186801|Clostridia	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS1_k127_2039018_2	497964.CfE428DRAFT_4447	3.225e-30	122.0	COG1721@1|root,COG1721@2|Bacteria,46VTM@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CMS1_k127_2052040_0	383372.Rcas_4424	2.36e-183	592.0	COG0457@1|root,COG3629@1|root,COG3899@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG3899@2|Bacteria,2G871@200795|Chloroflexi,375BC@32061|Chloroflexia	32061|Chloroflexia	K	transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,TPR_8
CMS1_k127_2052040_2	1158338.JNLJ01000001_gene734	4.57e-127	426.0	COG0442@1|root,COG0442@2|Bacteria,2G3SN@200783|Aquificae	200783|Aquificae	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
CMS1_k127_2052040_3	326427.Cagg_1565	3.006e-76	259.0	COG2353@1|root,COG2353@2|Bacteria,2G6G9@200795|Chloroflexi,376J9@32061|Chloroflexia	32061|Chloroflexia	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
CMS1_k127_2052040_1	1173028.ANKO01000250_gene2370	1.911e-127	424.0	COG0477@1|root,COG2814@2|Bacteria,1GQ8C@1117|Cyanobacteria,1HH9P@1150|Oscillatoriales	1117|Cyanobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_2053059_0	639030.JHVA01000001_gene1853	1.68e-165	522.0	COG4447@1|root,COG4447@2|Bacteria,3Y3TM@57723|Acidobacteria,2JHSZ@204432|Acidobacteriia	204432|Acidobacteriia	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR
CMS1_k127_2053059_4	1499967.BAYZ01000041_gene2312	6.437e-07	54.0	2DEJB@1|root,2ZN7M@2|Bacteria	2|Bacteria	S	Uncharacterised protein family (UPF0175)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0175
CMS1_k127_2053059_1	909663.KI867150_gene128	4.816e-110	393.0	COG0457@1|root,COG0457@2|Bacteria,1PDJ0@1224|Proteobacteria,43A33@68525|delta/epsilon subdivisions,2XA2B@28221|Deltaproteobacteria,2MRMF@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Soluble NSF attachment protein, SNAP	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
CMS1_k127_2053059_2	909663.KI867150_gene129	2.319e-23	112.0	COG1672@1|root,COG1672@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16
CMS1_k127_2053059_3	1089545.KB913037_gene9272	3.603e-09	64.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4E91C@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,TPR_12,Trans_reg_C
CMS1_k127_2053184_10	991905.SL003B_2625	3.651e-09	59.0	COG1796@1|root,COG1796@2|Bacteria,1QF8Z@1224|Proteobacteria	1224|Proteobacteria	L	Helix-hairpin-helix domain	dpbF	-	-	ko:K04477	-	-	-	-	ko00000	-	-	-	HHH_5,HHH_8
CMS1_k127_2053184_11	502025.Hoch_5010	3.772e-07	53.0	COG1796@1|root,COG1796@2|Bacteria,1QF8Z@1224|Proteobacteria,439QP@68525|delta/epsilon subdivisions,2X537@28221|Deltaproteobacteria,2Z01T@29|Myxococcales	28221|Deltaproteobacteria	L	Helix-hairpin-helix domain	dpbF	-	-	-	-	-	-	-	-	-	-	-	HHH_5,HHH_8
CMS1_k127_2053184_2	1121380.JNIW01000097_gene3406	1.721e-64	231.0	28JAJ@1|root,2Z95C@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2053184_3	373903.Hore_13850	1.368e-61	218.0	COG1573@1|root,COG1573@2|Bacteria,1V1SU@1239|Firmicutes,24E7B@186801|Clostridia	186801|Clostridia	L	Uracil DNA glycosylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	UDG
CMS1_k127_2053184_6	926569.ANT_06080	3.7e-51	192.0	COG2141@1|root,COG2141@2|Bacteria,2G5QC@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS1_k127_2053184_1	234267.Acid_2224	4.375e-161	515.0	COG0624@1|root,COG0624@2|Bacteria,3Y7TX@57723|Acidobacteria	57723|Acidobacteria	E	Peptidase family M20/M25/M40	-	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
CMS1_k127_2053184_5	1408254.T458_21085	1.687e-55	196.0	COG0662@1|root,COG0662@2|Bacteria,1V7K2@1239|Firmicutes,4HN60@91061|Bacilli,26WT8@186822|Paenibacillaceae	91061|Bacilli	G	Mannose-6-phosphate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS1_k127_2053184_8	338966.Ppro_0062	2.836e-18	97.0	COG1216@1|root,COG1216@2|Bacteria,1PIZU@1224|Proteobacteria,42ZNA@68525|delta/epsilon subdivisions,2WUX2@28221|Deltaproteobacteria,43VTF@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Uncharacterised nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
CMS1_k127_2053184_12	158500.BV97_02364	0.0002845	52.0	COG1493@1|root,COG1493@2|Bacteria,1RE0J@1224|Proteobacteria,2U8MR@28211|Alphaproteobacteria,2K5WU@204457|Sphingomonadales	204457|Sphingomonadales	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2053184_0	926569.ANT_13040	0.0	1128.0	COG1391@1|root,COG2844@1|root,COG1391@2|Bacteria,COG2844@2|Bacteria	2|Bacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnE	GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698	1.1.1.3,1.4.1.2,2.7.7.42,2.7.7.59,2.7.7.89	ko:K00003,ko:K00982,ko:K00990,ko:K06950,ko:K15371	ko00220,ko00250,ko00260,ko00270,ko00300,ko00430,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,ko02020,map00220,map00250,map00260,map00270,map00300,map00430,map00910,map01100,map01110,map01120,map01130,map01230,map02020	M00017,M00018	R00243,R01773,R01775	RC00006,RC00087,RC02799	ko00000,ko00001,ko00002,ko01000	-	-	-	GlnD_UR_UTase,GlnE,HD
CMS1_k127_2053184_7	331678.Cphamn1_1410	3.139e-44	166.0	COG4635@1|root,COG4635@2|Bacteria	2|Bacteria	CH	menaquinone-dependent protoporphyrinogen oxidase activity	-	-	1.3.5.3	ko:K00230	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R09489	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavodoxin_5
CMS1_k127_2053184_4	639030.JHVA01000001_gene411	1.69e-57	207.0	COG0491@1|root,COG0491@2|Bacteria,3Y4DN@57723|Acidobacteria,2JJ36@204432|Acidobacteriia	204432|Acidobacteriia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS1_k127_2060333_1	1194972.MVAC_08814	5.002e-11	63.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,232ME@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	fadD13	GO:0003674,GO:0003824,GO:0004321,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009268,GO:0009628,GO:0010447,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0030312,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051704,GO:0071944	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
CMS1_k127_2060333_0	1128421.JAGA01000003_gene3678	4.818e-52	211.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2NQCZ@2323|unclassified Bacteria	2|Bacteria	K	NB-ARC domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_22,BTAD,NB-ARC,TPR_10,TPR_12,TPR_8,Trans_reg_C
CMS1_k127_2062090_0	28072.Nos7524_5243	5.263e-180	587.0	COG1028@1|root,COG3321@1|root,COG1028@2|Bacteria,COG3321@2|Bacteria,1G1IB@1117|Cyanobacteria,1HJKD@1161|Nostocales	2|Bacteria	IQ	TIGRFAM Polyketide-type polyunsaturated fatty acid synthase, PfaA	-	-	-	ko:K15314	ko01059,ko01130,map01059,map01130	M00824,M00825	R11435	-	ko00000,ko00001,ko00002,ko01008	-	-	-	Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
CMS1_k127_2062090_2	449447.MAE_12770	6.633e-53	190.0	COG0824@1|root,COG0824@2|Bacteria,1GDHP@1117|Cyanobacteria	1117|Cyanobacteria	S	Thioesterase-like superfamily	-	-	-	ko:K15315	ko01059,map01059	-	R11436	RC00039,RC03437	ko00000,ko00001,ko01008	-	-	-	4HBT_2
CMS1_k127_2062090_1	485913.Krac_7300	6.733e-57	208.0	COG4977@1|root,COG4977@2|Bacteria,2G8UD@200795|Chloroflexi	200795|Chloroflexi	K	PFAM helix-turn-helix- domain containing protein AraC type	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
CMS1_k127_2064864_1	926550.CLDAP_30860	1.897e-186	595.0	COG0147@1|root,COG0147@2|Bacteria,2G5M7@200795|Chloroflexi	200795|Chloroflexi	H	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
CMS1_k127_2064864_6	314345.SPV1_12330	1.68e-79	286.0	COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria	1224|Proteobacteria	EH	Glutamine amidotransferase of anthranilate synthase	trpG	-	2.6.1.85,4.1.3.27	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2496	GATase
CMS1_k127_2064864_4	926569.ANT_05930	1.031e-110	377.0	COG0547@1|root,COG0547@2|Bacteria,2G5YV@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
CMS1_k127_2064864_7	756272.Plabr_0638	4.362e-67	237.0	COG0134@1|root,COG0134@2|Bacteria,2IX3M@203682|Planctomycetes	203682|Planctomycetes	E	Belongs to the TrpC family	trpC	GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
CMS1_k127_2064864_8	926550.CLDAP_30950	3.07e-64	228.0	COG0135@1|root,COG0135@2|Bacteria,2G6QB@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
CMS1_k127_2064864_9	1254432.SCE1572_08870	1.079e-56	199.0	COG1942@1|root,COG1942@2|Bacteria,1RDK8@1224|Proteobacteria,430P9@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Tautomerase enzyme	Z012_06190	-	-	-	-	-	-	-	-	-	-	-	Tautomerase_2
CMS1_k127_2064864_0	926569.ANT_05900	3.451e-192	606.0	COG0133@1|root,COG0133@2|Bacteria,2G5Q3@200795|Chloroflexi	200795|Chloroflexi	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS1_k127_2064864_3	316274.Haur_0220	8.843e-132	428.0	COG0180@1|root,COG0180@2|Bacteria,2G5SH@200795|Chloroflexi,37647@32061|Chloroflexia	32061|Chloroflexia	J	PFAM aminoacyl-tRNA synthetase class Ib	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
CMS1_k127_2064864_5	926550.CLDAP_27220	1.914e-82	281.0	COG0159@1|root,COG0159@2|Bacteria,2G6AY@200795|Chloroflexi	200795|Chloroflexi	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
CMS1_k127_2064864_10	867845.KI911784_gene864	2.117e-49	179.0	COG4401@1|root,COG4401@2|Bacteria,2G6VB@200795|Chloroflexi,375RY@32061|Chloroflexia	32061|Chloroflexia	E	PFAM Chorismate mutase of the AroH class	-	-	5.4.99.5	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_1
CMS1_k127_2064864_2	926569.ANT_01870	2.508e-142	460.0	COG2876@1|root,COG2876@2|Bacteria,2G643@200795|Chloroflexi	200795|Chloroflexi	E	PFAM DAHP synthetase I KDSA	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
CMS1_k127_2065630_14	441620.Mpop_1015	2.778e-05	55.0	COG1905@1|root,COG3743@1|root,COG1905@2|Bacteria,COG3743@2|Bacteria,1MWS2@1224|Proteobacteria,2TSEJ@28211|Alphaproteobacteria,1JSIB@119045|Methylobacteriaceae	28211|Alphaproteobacteria	C	TIGRFAM NADH-quinone oxidoreductase, E subunit	nuoE	-	1.6.5.3,1.6.99.3	ko:K00334,ko:K03943	ko00190,ko01100,ko04714,ko04723,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04714,map04723,map04932,map05010,map05012,map05016	M00143,M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1,3.D.1.6	-	-	2Fe-2S_thioredx
CMS1_k127_2065630_0	1191523.MROS_1660	7.694e-196	617.0	COG4992@1|root,COG4992@2|Bacteria	2|Bacteria	E	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity	rocD	GO:0003674,GO:0003824,GO:0004587,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	2.6.1.11,2.6.1.13,2.6.1.17	ko:K00819,ko:K00821	ko00220,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map00330,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R00667,R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iYO844.BSU40340	Aminotran_3
CMS1_k127_2065630_7	926550.CLDAP_16350	1.668e-32	135.0	COG0398@1|root,COG0398@2|Bacteria	2|Bacteria	M	Pfam SNARE associated Golgi protein	yjbF	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
CMS1_k127_2065630_4	926550.CLDAP_16790	1.313e-58	209.0	COG2129@1|root,COG2129@2|Bacteria,2G8MC@200795|Chloroflexi	200795|Chloroflexi	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
CMS1_k127_2065630_1	926569.ANT_03360	2.066e-92	311.0	COG0077@1|root,COG0077@2|Bacteria,2G6AP@200795|Chloroflexi	200795|Chloroflexi	E	amino acid-binding ACT domain protein	pheA	-	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	PDT
CMS1_k127_2065630_6	926569.ANT_14050	7.415e-40	154.0	COG1611@1|root,COG1611@2|Bacteria	2|Bacteria	S	cytokinin biosynthetic process	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
CMS1_k127_2065630_9	266117.Rxyl_0216	8.903e-28	127.0	COG4552@1|root,COG4552@2|Bacteria,2GNXZ@201174|Actinobacteria,4CTUU@84995|Rubrobacteria	84995|Rubrobacteria	S	Sterol carrier protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9,SCP2_2
CMS1_k127_2065630_15	1379698.RBG1_1C00001G0125	9.998e-05	48.0	2EGJW@1|root,3110Q@2|Bacteria,2NS2A@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2065630_13	316274.Haur_0188	1.907e-19	97.0	28MEN@1|root,2ZASA@2|Bacteria,2G97S@200795|Chloroflexi,375P3@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2065630_8	459349.CLOAM1196	1.326e-28	123.0	29ZH8@1|root,30MGZ@2|Bacteria,2NQ83@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2065630_12	926569.ANT_00370	7.687e-23	117.0	COG1187@1|root,COG1187@2|Bacteria	2|Bacteria	J	pseudouridine synthase activity	rluB	-	5.4.99.19,5.4.99.20,5.4.99.22	ko:K06178,ko:K06181,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
CMS1_k127_2065630_11	926569.ANT_00380	1.445e-25	115.0	2ANS9@1|root,31DS7@2|Bacteria,2G7CA@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2065630_2	247490.KSU1_B0657	3.577e-89	316.0	COG1070@1|root,COG1070@2|Bacteria,2IY9E@203682|Planctomycetes	203682|Planctomycetes	G	MutL protein	-	-	-	-	-	-	-	-	-	-	-	-	MutL
CMS1_k127_2065630_10	765420.OSCT_1709	2.456e-27	124.0	28II6@1|root,2Z8JB@2|Bacteria,2G7FN@200795|Chloroflexi,375CV@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2065630_5	525904.Tter_1424	3.378e-58	213.0	COG0524@1|root,COG0524@2|Bacteria,2NRAA@2323|unclassified Bacteria	2|Bacteria	G	pfkB family carbohydrate kinase	-	-	2.7.1.3	ko:K00846	ko00051,ko01100,ko01120,map00051,map01100,map01120	-	R00866,R03819	RC00002,RC00017,RC00608	ko00000,ko00001,ko01000,ko04147	-	-	-	PfkB,Rieske
CMS1_k127_2065630_3	926550.CLDAP_16480	3.346e-63	232.0	COG0745@1|root,COG1672@1|root,COG0745@2|Bacteria,COG1672@2|Bacteria,2G778@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
CMS1_k127_2071330_1	926569.ANT_00770	4.697e-105	355.0	COG2373@1|root,COG2373@2|Bacteria,2G8BN@200795|Chloroflexi	200795|Chloroflexi	S	A-macroglobulin receptor	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_N_2,A2M_comp,A2M_recep,Thiol-ester_cl
CMS1_k127_2071330_7	1469607.KK073768_gene652	4.938e-06	54.0	COG4113@1|root,COG4113@2|Bacteria,1G6BG@1117|Cyanobacteria,1HQ44@1161|Nostocales	1117|Cyanobacteria	S	PIN domain	-	-	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
CMS1_k127_2071330_0	309801.trd_0072	7.6e-111	366.0	COG0524@1|root,COG0524@2|Bacteria,2G7YB@200795|Chloroflexi,27YGK@189775|Thermomicrobia	189775|Thermomicrobia	G	pfkB family carbohydrate kinase	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
CMS1_k127_2071330_3	485916.Dtox_0723	9.292e-61	216.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,24FR4@186801|Clostridia,261JF@186807|Peptococcaceae	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
CMS1_k127_2071330_2	926569.ANT_20590	7.915e-89	304.0	COG4260@1|root,COG4260@2|Bacteria,2G6J2@200795|Chloroflexi	200795|Chloroflexi	S	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,HTH_17,zinc_ribbon_2
CMS1_k127_2071330_6	926569.ANT_20600	3.285e-28	120.0	arCOG05710@1|root,33AIT@2|Bacteria,2G9CR@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2071330_5	926550.CLDAP_09640	1.965e-42	161.0	COG1996@1|root,COG1996@2|Bacteria	2|Bacteria	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4379
CMS1_k127_2071330_4	926550.CLDAP_09650	3.044e-59	216.0	COG4907@1|root,COG4907@2|Bacteria	2|Bacteria	P	membrane protein (DUF2207)	yciQ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF2207
CMS1_k127_2072555_4	221288.JH992901_gene4291	4.259e-16	78.0	COG0436@1|root,COG0436@2|Bacteria,1G202@1117|Cyanobacteria,1JKEM@1189|Stigonemataceae	1117|Cyanobacteria	E	Cys/Met metabolism PLP-dependent enzyme	-	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS1_k127_2072555_6	526227.Mesil_0390	3.528e-12	67.0	COG1694@1|root,COG1694@2|Bacteria,1WK7E@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM MazG nucleotide pyrophosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	MazG
CMS1_k127_2072555_5	479434.Sthe_2194	1.553e-15	83.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,T4_deiodinase
CMS1_k127_2072555_3	926550.CLDAP_20290	1.031e-49	180.0	COG0346@1|root,COG0346@2|Bacteria,2G8UR@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS1_k127_2072555_1	1131730.BAVI_25444	5.215e-81	279.0	COG0329@1|root,COG0329@2|Bacteria,1UBSQ@1239|Firmicutes,4IN7W@91061|Bacilli,1ZMZY@1386|Bacillus	91061|Bacilli	EM	Dihydrodipicolinate synthetase family	-	-	-	-	-	-	-	-	-	-	-	-	DHDPS
CMS1_k127_2072555_0	1469245.JFBG01000004_gene363	1.099e-91	313.0	COG1062@1|root,COG1062@2|Bacteria,1MUK4@1224|Proteobacteria,1S0H1@1236|Gammaproteobacteria,1X2C5@135613|Chromatiales	1236|Gammaproteobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_2072555_2	195250.CM001776_gene1213	3.586e-52	197.0	COG0028@1|root,COG0028@2|Bacteria,1G0KQ@1117|Cyanobacteria,1GYI7@1129|Synechococcus	1117|Cyanobacteria	EH	Belongs to the TPP enzyme family	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS1_k127_2075102_2	1254432.SCE1572_31205	2.315e-113	372.0	COG0076@1|root,COG0076@2|Bacteria,1MWUX@1224|Proteobacteria,42MYA@68525|delta/epsilon subdivisions,2WKFB@28221|Deltaproteobacteria,2YUKP@29|Myxococcales	28221|Deltaproteobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
CMS1_k127_2075102_16	479434.Sthe_1755	9.021e-29	124.0	COG5343@1|root,COG5343@2|Bacteria	2|Bacteria	S	Anti-sigma-K factor rskA	-	-	-	-	-	-	-	-	-	-	-	-	RskA,zf-HC2
CMS1_k127_2075102_15	316274.Haur_4650	6.442e-38	150.0	COG1595@1|root,COG1595@2|Bacteria,2G6UE@200795|Chloroflexi,3778F@32061|Chloroflexia	32061|Chloroflexia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_2075102_19	1303518.CCALI_00007	2.888e-21	96.0	COG3011@1|root,COG3011@2|Bacteria	2|Bacteria	CH	Protein conserved in bacteria	yuxK	-	-	-	-	-	-	-	-	-	-	-	DUF393
CMS1_k127_2075102_12	1499967.BAYZ01000095_gene4130	2.094e-54	200.0	COG0775@1|root,COG0775@2|Bacteria	2|Bacteria	F	adenosylhomocysteine nucleosidase activity	pfs	-	3.2.2.1,3.2.2.9,4.1.99.14	ko:K01239,ko:K01243,ko:K03716	ko00230,ko00270,ko00760,ko01100,ko01230,map00230,map00270,map00760,map01100,map01230	M00034,M00609	R00194,R01245,R01273,R01401,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
CMS1_k127_2075102_10	765420.OSCT_2202	1.946e-57	212.0	COG1597@1|root,COG1597@2|Bacteria,2G70R@200795|Chloroflexi,375F4@32061|Chloroflexia	32061|Chloroflexia	I	diacylglycerol kinase, catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
CMS1_k127_2075102_9	321332.CYB_2184	5.4e-59	212.0	COG2518@1|root,COG2518@2|Bacteria,1G5KC@1117|Cyanobacteria,1H0H3@1129|Synechococcus	1117|Cyanobacteria	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
CMS1_k127_2075102_23	926569.ANT_20470	5.806e-08	58.0	COG4980@1|root,COG4980@2|Bacteria	2|Bacteria	D	gas vesicle protein	XK27_07760	-	-	-	-	-	-	-	-	-	-	-	YtxH
CMS1_k127_2075102_20	316274.Haur_2691	1.807e-16	85.0	COG1664@1|root,COG1664@2|Bacteria,2G7DZ@200795|Chloroflexi,375IM@32061|Chloroflexia	32061|Chloroflexia	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
CMS1_k127_2075102_4	926550.CLDAP_01170	1.936e-90	319.0	COG0747@1|root,COG0747@2|Bacteria,2G6MN@200795|Chloroflexi	200795|Chloroflexi	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_2075102_13	926550.CLDAP_32530	4.017e-42	162.0	COG3576@1|root,COG3576@2|Bacteria,2GA9W@200795|Chloroflexi	200795|Chloroflexi	S	Pfam:Pyridox_oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
CMS1_k127_2075102_17	98439.AJLL01000002_gene1725	6.076e-26	117.0	arCOG12117@1|root,2Z9N1@2|Bacteria,1G2YP@1117|Cyanobacteria,1JGUU@1189|Stigonemataceae	1117|Cyanobacteria	S	Protein of unknown function (DUF3891)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3891
CMS1_k127_2075102_22	324602.Caur_0926	6.372e-10	71.0	COG5662@1|root,COG5662@2|Bacteria,2G9S9@200795|Chloroflexi	200795|Chloroflexi	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
CMS1_k127_2075102_11	326427.Cagg_2227	1.147e-55	200.0	COG1595@1|root,COG1595@2|Bacteria,2G6MG@200795|Chloroflexi,375K5@32061|Chloroflexia	32061|Chloroflexia	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_2075102_24	1499680.CCFE01000025_gene3185	6.251e-06	51.0	2AWWM@1|root,31NU5@2|Bacteria,1TZQ8@1239|Firmicutes,4II4F@91061|Bacilli,1ZJ4J@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2075102_21	926550.CLDAP_00160	3.033e-11	75.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	3.4.21.107,3.5.1.28	ko:K01448,ko:K04771	ko01503,ko02020,map01503,map02020	M00727,M00728	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko03036,ko03110	-	-	-	SH3_3
CMS1_k127_2075102_3	926550.CLDAP_00150	1.703e-103	371.0	COG0664@1|root,COG0664@2|Bacteria,2G902@200795|Chloroflexi	200795|Chloroflexi	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_6,Fer4_7,cNMP_binding
CMS1_k127_2075102_5	886293.Sinac_4922	3.112e-89	302.0	COG1028@1|root,COG1028@2|Bacteria,2IX26@203682|Planctomycetes	203682|Planctomycetes	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS1_k127_2075102_8	344747.PM8797T_12993	1.452e-63	228.0	COG1402@1|root,COG1402@2|Bacteria	2|Bacteria	I	creatininase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
CMS1_k127_2075102_14	867845.KI911784_gene1128	4.022e-41	163.0	COG1091@1|root,COG1091@2|Bacteria,2G9A2@200795|Chloroflexi,375MR@32061|Chloroflexia	32061|Chloroflexia	M	PFAM NAD-dependent epimerase dehydratase	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
CMS1_k127_2075102_6	926550.CLDAP_04380	2.422e-76	270.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,2G6Q7@200795|Chloroflexi	200795|Chloroflexi	M	Peptidoglycan-binding LysM	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23,SH3_3
CMS1_k127_2075102_0	926550.CLDAP_04360	3.283e-194	617.0	COG1158@1|root,COG1158@2|Bacteria,2G5UQ@200795|Chloroflexi	200795|Chloroflexi	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
CMS1_k127_2075102_1	926550.CLDAP_16500	1.75e-150	484.0	COG0158@1|root,COG0158@2|Bacteria	2|Bacteria	G	fructose 1,6-bisphosphate 1-phosphatase activity	fbp	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016043,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0022607,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901576	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iUTI89_1310.UTI89_C4836,ic_1306.c5329	FBPase
CMS1_k127_2075102_7	690850.Desaf_0305	4.182e-67	235.0	COG0176@1|root,COG0176@2|Bacteria,1N9G3@1224|Proteobacteria,42MCK@68525|delta/epsilon subdivisions,2WXRI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	-	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
CMS1_k127_2086111_0	765420.OSCT_0520	5.02e-79	268.0	COG1884@1|root,COG1884@2|Bacteria,2G62T@200795|Chloroflexi,374XE@32061|Chloroflexia	32061|Chloroflexia	I	TIGRFAM methylmalonyl-CoA mutase, large subunit	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
CMS1_k127_2086111_2	1538295.JY96_12825	1.708e-31	127.0	COG0745@1|root,COG0745@2|Bacteria,1N3FI@1224|Proteobacteria,2VU5F@28216|Betaproteobacteria,1KME2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS1_k127_2086111_1	1380370.JIBA01000015_gene376	6.534e-59	234.0	COG0642@1|root,COG2205@2|Bacteria,2I2M2@201174|Actinobacteria,4FFYD@85021|Intrasporangiaceae	201174|Actinobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,GAF_2,HAMP,HATPase_c,HisKA,Response_reg
CMS1_k127_2094467_2	1128421.JAGA01000002_gene312	3.184e-84	297.0	COG0859@1|root,COG0859@2|Bacteria	2|Bacteria	M	ADP-heptose-lipopolysaccharide heptosyltransferase activity	-	-	-	ko:K02843,ko:K02849	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
CMS1_k127_2094467_1	926550.CLDAP_29920	1.127e-103	349.0	COG0438@1|root,COG0438@2|Bacteria,2G6I1@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
CMS1_k127_2094467_0	926550.CLDAP_29930	9.291e-110	366.0	COG0438@1|root,COG0438@2|Bacteria,2G82Z@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS1_k127_2094467_3	1160707.AJIK01000025_gene2542	1.014e-29	129.0	COG0491@1|root,COG0491@2|Bacteria,1U98Y@1239|Firmicutes,4HDNC@91061|Bacilli,26F90@186818|Planococcaceae	91061|Bacilli	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS1_k127_2094467_4	1279019.ARQK01000049_gene45	0.0005348	52.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,1RNW8@1236|Gammaproteobacteria,1WX9J@135613|Chromatiales	135613|Chromatiales	O	PFAM Band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
CMS1_k127_2117093_7	309807.SRU_2686	1.105e-07	55.0	COG0661@1|root,COG0661@2|Bacteria,4NDUP@976|Bacteroidetes,1FJEM@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	ABC1 family	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
CMS1_k127_2117093_6	1235790.C805_02338	3.113e-16	83.0	COG1848@1|root,COG1848@2|Bacteria,1VCDC@1239|Firmicutes,24P6P@186801|Clostridia	186801|Clostridia	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
CMS1_k127_2117093_5	368407.Memar_1051	2.357e-18	100.0	COG3187@1|root,arCOG03952@2157|Archaea,2Y55P@28890|Euryarchaeota,2NBFA@224756|Methanomicrobia	224756|Methanomicrobia	O	META domain	-	-	-	-	-	-	-	-	-	-	-	-	META
CMS1_k127_2117093_4	926569.ANT_22190	2.357e-18	100.0	COG1572@1|root,COG1572@2|Bacteria,2G9M8@200795|Chloroflexi	2|Bacteria	S	Ig-like domain from next to BRCA1 gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,N_BRCA1_IG
CMS1_k127_2117093_1	926550.CLDAP_05430	4.342e-48	197.0	COG0834@1|root,COG0834@2|Bacteria,2G81G@200795|Chloroflexi	200795|Chloroflexi	ET	PFAM extracellular solute-binding protein, family 3	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
CMS1_k127_2117093_0	868131.MSWAN_2326	6.024e-132	445.0	COG1950@1|root,arCOG09731@2157|Archaea,2Y2F9@28890|Euryarchaeota,23PAN@183925|Methanobacteria	183925|Methanobacteria	S	Mycobacterial 4 TMS phage holin, superfamily IV	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2,Phosphodiest
CMS1_k127_2117093_2	1128421.JAGA01000002_gene1372	1.748e-40	160.0	COG3568@1|root,COG3568@2|Bacteria	2|Bacteria	N	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CMS1_k127_2117093_3	1487953.JMKF01000069_gene116	6.107e-20	98.0	COG1280@1|root,COG1280@2|Bacteria,1G5MM@1117|Cyanobacteria,1HBTI@1150|Oscillatoriales	1117|Cyanobacteria	E	Sap, sulfolipid-1-addressing protein	-	-	-	-	-	-	-	-	-	-	-	-	SfLAP
CMS1_k127_2125677_5	1040986.ATYO01000003_gene5921	4.313e-05	48.0	COG2267@1|root,COG3629@1|root,COG2267@2|Bacteria,COG3629@2|Bacteria,1QU9N@1224|Proteobacteria,2TW44@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IT	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CMS1_k127_2125677_1	670487.Ocepr_1053	3.425e-30	126.0	COG4843@1|root,COG4843@2|Bacteria,1WKI2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179
CMS1_k127_2125677_2	926569.ANT_26580	6.798e-14	74.0	COG3462@1|root,COG3462@2|Bacteria	2|Bacteria	S	membrane protein (DUF2078)	-	-	-	ko:K08982	-	-	-	-	ko00000	-	-	-	SHOCT
CMS1_k127_2125677_3	1379281.AVAG01000045_gene368	3.692e-08	57.0	COG3462@1|root,COG3462@2|Bacteria,1QE33@1224|Proteobacteria,43EKD@68525|delta/epsilon subdivisions,2X0Z4@28221|Deltaproteobacteria,2MDTR@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Short C-terminal domain	-	-	-	ko:K08982	-	-	-	-	ko00000	-	-	-	SHOCT
CMS1_k127_2125677_0	1449126.JQKL01000058_gene2239	5.87e-35	145.0	COG1842@1|root,COG1842@2|Bacteria,1V454@1239|Firmicutes	1239|Firmicutes	KT	Phage shock protein A	pspA	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
CMS1_k127_2125677_4	1463887.KL590001_gene5643	2.905e-06	53.0	2E3Z4@1|root,32YW2@2|Bacteria,2IQZ7@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2128879_4	1295642.H839_10673	0.0008195	42.0	COG0388@1|root,COG0388@2|Bacteria,1TQR9@1239|Firmicutes,4HDUI@91061|Bacilli,1WEZK@129337|Geobacillus	91061|Bacilli	S	Carbon-nitrogen hydrolase	-	-	3.5.5.1	ko:K01501	ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120	-	R00540,R01887,R03093,R03542,R05591,R07855	RC00315,RC00325,RC00617,RC00959,RC02811	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
CMS1_k127_2128879_3	235985.BBPN01000015_gene5151	1.881e-59	218.0	COG1609@1|root,COG1609@2|Bacteria,2GJV7@201174|Actinobacteria,2NG8U@228398|Streptacidiphilus	201174|Actinobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
CMS1_k127_2128879_0	649638.Trad_1849	2.29e-148	480.0	COG4608@1|root,COG4608@2|Bacteria,1WI6F@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
CMS1_k127_2128879_1	1120950.KB892761_gene5820	2.196e-132	431.0	COG0444@1|root,COG0444@2|Bacteria,2GIXV@201174|Actinobacteria	201174|Actinobacteria	EP	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
CMS1_k127_2128879_2	492774.JQMB01000003_gene2515	7.578e-131	422.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,2TUWG@28211|Alphaproteobacteria,4B9HC@82115|Rhizobiaceae	28211|Alphaproteobacteria	EP	ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
CMS1_k127_2130074_1	1487953.JMKF01000091_gene5328	2.847e-58	210.0	COG2207@1|root,COG2207@2|Bacteria,1G4YH@1117|Cyanobacteria	1117|Cyanobacteria	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
CMS1_k127_2130074_2	439235.Dalk_4961	1.74e-52	191.0	COG1280@1|root,COG1280@2|Bacteria,1RCFI@1224|Proteobacteria,42TYV@68525|delta/epsilon subdivisions,2WQTZ@28221|Deltaproteobacteria,2MKP4@213118|Desulfobacterales	28221|Deltaproteobacteria	E	LysE type translocator	-	-	-	ko:K11249	-	-	-	-	ko00000,ko02000	2.A.76.1.4	-	-	LysE
CMS1_k127_2130074_5	1894.JOER01000014_gene5764	3.529e-05	49.0	COG0596@1|root,COG0596@2|Bacteria,2GK43@201174|Actinobacteria	201174|Actinobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS1_k127_2130074_3	643473.KB235930_gene3902	5.066e-16	87.0	COG0451@1|root,COG0451@2|Bacteria,1GBH0@1117|Cyanobacteria,1HQM0@1161|Nostocales	1117|Cyanobacteria	M	Male sterility protein	-	-	1.1.1.203	ko:K18981	ko00053,map00053	-	R10841	RC00066	ko00000,ko00001,ko01000	-	-	-	Epimerase
CMS1_k127_2130074_0	756067.MicvaDRAFT_2831	1.278e-103	345.0	arCOG10456@1|root,2ZA6T@2|Bacteria,1G2PI@1117|Cyanobacteria,1HBZF@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2130074_4	1227484.C471_10025	1.019e-08	57.0	COG2217@1|root,arCOG01576@2157|Archaea,2XT3T@28890|Euryarchaeota,23S6X@183963|Halobacteria	183963|Halobacteria	P	copper-translocating P-type ATPase	-	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase
CMS1_k127_213040_2	926550.CLDAP_13140	2.176e-07	59.0	COG5305@1|root,COG5305@2|Bacteria,2G7EE@200795|Chloroflexi	2|Bacteria	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS1_k127_213040_0	1499967.BAYZ01000061_gene5932	6.832e-75	268.0	COG0438@1|root,COG0438@2|Bacteria,2NNTN@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferases group 1	-	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CMS1_k127_213040_1	926550.CLDAP_32470	3.213e-30	133.0	COG1807@1|root,COG1807@2|Bacteria,2G8DG@200795|Chloroflexi	200795|Chloroflexi	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS1_k127_2131324_2	639030.JHVA01000001_gene3837	2.363e-10	68.0	2C4AC@1|root,30014@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2136370_0	573413.Spirs_4115	4.312e-201	640.0	COG1640@1|root,COG1640@2|Bacteria,2J5U4@203691|Spirochaetes	203691|Spirochaetes	G	4-alpha-glucanotransferase	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
CMS1_k127_2136370_2	357808.RoseRS_2858	2.803e-58	213.0	COG3375@1|root,COG3375@2|Bacteria,2G8MH@200795|Chloroflexi,37765@32061|Chloroflexia	32061|Chloroflexia	M	carboxylic acid catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2136370_1	357808.RoseRS_2859	8.879e-135	443.0	COG4948@1|root,COG4948@2|Bacteria,2G704@200795|Chloroflexi,3771P@32061|Chloroflexia	32061|Chloroflexia	H	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	-	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
CMS1_k127_2136370_3	1121403.AUCV01000002_gene529	1.309e-40	155.0	COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,42RJX@68525|delta/epsilon subdivisions,2WQNR@28221|Deltaproteobacteria,2MJWZ@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
CMS1_k127_2136370_4	1128421.JAGA01000002_gene822	7.886e-30	122.0	COG1385@1|root,COG1385@2|Bacteria	2|Bacteria	J	rRNA (uridine-N3-)-methyltransferase activity	rsmE	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
CMS1_k127_2140635_0	518766.Rmar_2012	6.443e-314	973.0	COG4263@1|root,COG4263@2|Bacteria,4NFNE@976|Bacteroidetes,1FIVE@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Nitrous oxide reductase	nosZ	-	1.7.2.4	ko:K00376	ko00910,ko01120,map00910,map01120	M00529	R02804	RC02861	ko00000,ko00001,ko00002,ko01000	-	-	-	-
CMS1_k127_2140635_3	926550.CLDAP_07160	3.027e-86	290.0	COG4314@1|root,COG4314@2|Bacteria	2|Bacteria	C	lipoprotein involved in nitrous oxide reduction	nosL	-	-	ko:K19342	-	-	-	-	ko00000	-	-	-	NosL
CMS1_k127_2140635_1	479434.Sthe_0737	1.183e-165	549.0	COG1131@1|root,COG3420@1|root,COG1131@2|Bacteria,COG3420@2|Bacteria,2G7PN@200795|Chloroflexi,27Z0E@189775|Thermomicrobia	189775|Thermomicrobia	P	Domain present in carbohydrate binding proteins and sugar hydrolses	-	-	-	ko:K07218	-	-	-	-	ko00000	-	-	-	ABC_tran,NosD
CMS1_k127_2140635_2	926550.CLDAP_07190	9.803e-90	303.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	nosY	-	-	ko:K19341	ko02010,map02010	M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.132.2	-	-	ABC2_membrane_2
CMS1_k127_2140635_4	309801.trd_A0190	7.817e-09	60.0	COG4314@1|root,COG4314@2|Bacteria,2G91T@200795|Chloroflexi,27ZA8@189775|Thermomicrobia	189775|Thermomicrobia	C	NosL	-	-	-	ko:K19342	-	-	-	-	ko00000	-	-	-	NosL
CMS1_k127_2141963_7	321332.CYB_1990	3.638e-64	225.0	COG2377@1|root,COG2377@2|Bacteria,1G0QJ@1117|Cyanobacteria,1GZ23@1129|Synechococcus	1117|Cyanobacteria	F	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
CMS1_k127_2141963_3	926550.CLDAP_35970	1.764e-138	451.0	COG1820@1|root,COG1820@2|Bacteria,2G6HC@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
CMS1_k127_2141963_4	926569.ANT_08060	9.117e-121	396.0	COG0449@1|root,COG0449@2|Bacteria,2G5V6@200795|Chloroflexi	200795|Chloroflexi	M	PFAM sugar isomerase (SIS)	-	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	SIS
CMS1_k127_2141963_6	357808.RoseRS_0805	1.131e-93	312.0	COG0745@1|root,COG0745@2|Bacteria,2G8EK@200795|Chloroflexi,376Y5@32061|Chloroflexia	32061|Chloroflexia	K	PFAM response regulator receiver	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_2141963_5	383372.Rcas_1175	7.717e-120	396.0	COG3850@1|root,COG5002@1|root,COG3850@2|Bacteria,COG5002@2|Bacteria,2GAJ1@200795|Chloroflexi,376G4@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase HAMP region domain protein	-	-	2.7.13.3	ko:K10819	-	-	-	-	ko00000,ko01000	-	-	-	HAMP,HATPase_c,HisKA
CMS1_k127_2141963_8	1120968.AUBX01000010_gene1301	2.124e-51	186.0	COG2391@1|root,COG2391@2|Bacteria,4NM6E@976|Bacteroidetes,47TWC@768503|Cytophagia	976|Bacteroidetes	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
CMS1_k127_2141963_10	1121859.KB890739_gene2466	4.67e-44	164.0	COG2391@1|root,COG2391@2|Bacteria,4NQ9C@976|Bacteroidetes	976|Bacteroidetes	S	Transporter	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
CMS1_k127_2141963_1	324602.Caur_3202	4.073e-236	741.0	COG0437@1|root,COG3301@1|root,COG0437@2|Bacteria,COG3301@2|Bacteria,2G5N2@200795|Chloroflexi,376PA@32061|Chloroflexia	32061|Chloroflexia	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_11,NrfD
CMS1_k127_2141963_0	926550.CLDAP_30470	0.0	1431.0	COG0243@1|root,COG0243@2|Bacteria,2G5ZB@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CMS1_k127_2141963_2	1118054.CAGW01000049_gene1684	4.175e-188	598.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1TSQZ@1239|Firmicutes,4HCYZ@91061|Bacilli,274UU@186822|Paenibacillaceae	91061|Bacilli	P	Rhodanese Homology Domain	baeB	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B,Rhodanese
CMS1_k127_2141963_9	485913.Krac_0465	2.016e-44	166.0	COG1853@1|root,COG1853@2|Bacteria	2|Bacteria	S	FMN binding	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
CMS1_k127_2141963_11	324602.Caur_3200	2.019e-31	136.0	COG3381@1|root,COG3381@2|Bacteria,2G96P@200795|Chloroflexi,377BV@32061|Chloroflexia	32061|Chloroflexia	S	Nitrate reductase delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_del
CMS1_k127_2141963_12	1480694.DC28_13850	5.019e-23	104.0	COG2391@1|root,COG2391@2|Bacteria	2|Bacteria	-	-	yeeE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
CMS1_k127_2142585_1	1242864.D187_000963	3.359e-54	199.0	COG3393@1|root,COG3393@2|Bacteria	2|Bacteria	S	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,FR47,GNAT_acetyltran
CMS1_k127_2142585_3	118173.KB235914_gene2547	4.824e-18	86.0	COG1476@1|root,COG1476@2|Bacteria,1GFFE@1117|Cyanobacteria,1HG93@1150|Oscillatoriales	1117|Cyanobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
CMS1_k127_2142585_2	1157490.EL26_17645	1.479e-19	98.0	COG3836@1|root,COG3836@2|Bacteria,1UZZG@1239|Firmicutes,4HEP6@91061|Bacilli,27A35@186823|Alicyclobacillaceae	91061|Bacilli	G	HpcH/HpaI aldolase/citrate lyase family	-	-	4.1.2.52	ko:K02510	ko00350,ko01120,map00350,map01120	-	R01645,R01647	RC00307,RC00572,RC00574,RC03057	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
CMS1_k127_2142585_0	1380394.JADL01000014_gene150	1.214e-94	316.0	COG1024@1|root,COG1024@2|Bacteria,1MXBB@1224|Proteobacteria,2TU4V@28211|Alphaproteobacteria,2JQJE@204441|Rhodospirillales	204441|Rhodospirillales	I	COG1024 Enoyl-CoA hydratase carnithine racemase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS1_k127_2149783_18	1121468.AUBR01000074_gene1113	1.57e-13	83.0	COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,247KM@186801|Clostridia,42EM0@68295|Thermoanaerobacterales	186801|Clostridia	D	PFAM cell divisionFtsK SpoIIIE	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
CMS1_k127_2149783_3	234267.Acid_1970	2.675e-108	364.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,DUF2048,Peptidase_S9
CMS1_k127_2149783_20	1433126.BN938_2028	6.736e-06	51.0	COG1894@1|root,COG1894@2|Bacteria,4NFB5@976|Bacteroidetes,2FN7A@200643|Bacteroidia	976|Bacteroidetes	C	COG1894 NADH ubiquinone oxidoreductase, NADH-binding (51 kD) subunit	nuoF	-	1.12.1.3,1.6.5.3	ko:K00335,ko:K18331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
CMS1_k127_2149783_21	196490.AUEZ01000049_gene27	3.359e-05	51.0	COG2141@1|root,COG2141@2|Bacteria,1NX0H@1224|Proteobacteria,2U42F@28211|Alphaproteobacteria,3JZMR@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS1_k127_2149783_5	316274.Haur_0769	2.396e-99	341.0	COG0204@1|root,COG0204@2|Bacteria	2|Bacteria	I	Acyl-transferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
CMS1_k127_2149783_11	1457250.BBMO01000002_gene2052	1.153e-35	143.0	COG2335@1|root,arCOG03335@2157|Archaea,2Y78U@28890|Euryarchaeota,240QQ@183963|Halobacteria	183963|Halobacteria	M	Four repeated domains in the Fasciclin I family of proteins, present in many other contexts.	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
CMS1_k127_2149783_17	309801.trd_A0765	1.337e-13	83.0	COG1475@1|root,COG1475@2|Bacteria,2G6EK@200795|Chloroflexi,27XRN@189775|Thermomicrobia	189775|Thermomicrobia	K	ParB-like nuclease domain	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
CMS1_k127_2149783_10	999423.HMPREF9161_01198	2.16e-44	171.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,4H331@909932|Negativicutes	909932|Negativicutes	D	Sporulation initiation inhibitor protein Soj	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
CMS1_k127_2149783_2	864702.OsccyDRAFT_0820	2.501e-115	380.0	COG2374@1|root,COG2374@2|Bacteria,1G409@1117|Cyanobacteria,1H9FB@1150|Oscillatoriales	1117|Cyanobacteria	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CMS1_k127_2149783_13	176280.SE_0549	3.428e-20	102.0	COG0391@1|root,COG0391@2|Bacteria,1TPNV@1239|Firmicutes,4HA0Z@91061|Bacilli,4GXWK@90964|Staphylococcaceae	91061|Bacilli	S	Required for morphogenesis under gluconeogenic growth conditions	yvcK	-	-	-	-	-	-	-	-	-	-	-	UPF0052
CMS1_k127_2149783_6	926550.CLDAP_22360	1.965e-92	320.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_2149783_15	551789.ATVJ01000001_gene2069	1.41e-18	93.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,2U5A1@28211|Alphaproteobacteria,440ZU@69657|Hyphomonadaceae	28211|Alphaproteobacteria	K	Sigma-70, region 4	sigE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_2149783_7	237368.SCABRO_03556	2.611e-80	287.0	COG1357@1|root,COG1357@2|Bacteria,2J0M1@203682|Planctomycetes	203682|Planctomycetes	S	Pentapeptide repeats (9 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
CMS1_k127_2149783_12	675635.Psed_4410	8.669e-31	126.0	COG1846@1|root,COG1846@2|Bacteria,2IJHQ@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator (MarR	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
CMS1_k127_2149783_9	1128421.JAGA01000003_gene3248	3.773e-60	223.0	COG0477@1|root,COG2814@2|Bacteria,2NQ08@2323|unclassified Bacteria	2|Bacteria	EGP	MFS_1 like family	-	-	-	ko:K08151,ko:K08153	-	M00668,M00717	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75,2.A.1.2.8	-	-	MFS_1,MFS_1_like,Sugar_tr
CMS1_k127_2149783_8	1121403.AUCV01000017_gene4441	2.463e-64	228.0	COG0252@1|root,COG0252@2|Bacteria,1RHAW@1224|Proteobacteria,42SNH@68525|delta/epsilon subdivisions,2WPQC@28221|Deltaproteobacteria,2MK6U@213118|Desulfobacterales	28221|Deltaproteobacteria	EJ	Asparaginase, N-terminal	aspG	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
CMS1_k127_2149783_4	926569.ANT_07850	5.837e-103	340.0	COG2120@1|root,COG2120@2|Bacteria,2G6FB@200795|Chloroflexi	200795|Chloroflexi	S	PFAM LmbE family protein	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
CMS1_k127_2149783_1	316274.Haur_3716	4.943e-123	406.0	2DBVK@1|root,2ZBBH@2|Bacteria,2G7SF@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2149783_19	502025.Hoch_2847	1.815e-08	66.0	COG2105@1|root,COG2105@2|Bacteria,1N94Q@1224|Proteobacteria,42X7M@68525|delta/epsilon subdivisions,2WSFG@28221|Deltaproteobacteria,2YVYK@29|Myxococcales	28221|Deltaproteobacteria	S	PFAM AIG2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	GGACT
CMS1_k127_2149783_16	67373.JOBF01000007_gene2261	4.017e-14	83.0	COG3576@1|root,COG3576@2|Bacteria,2IKU6@201174|Actinobacteria	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
CMS1_k127_2149783_0	926550.CLDAP_06140	1.116e-145	467.0	COG1087@1|root,COG1087@2|Bacteria,2G5QM@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
CMS1_k127_2149783_14	926692.AZYG01000086_gene723	1.182e-19	91.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,249IC@186801|Clostridia	186801|Clostridia	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_2151817_2	1267535.KB906767_gene4712	6.206e-65	230.0	COG2159@1|root,COG2159@2|Bacteria,3Y2HY@57723|Acidobacteria,2JI2D@204432|Acidobacteriia	204432|Acidobacteriia	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CMS1_k127_2151817_4	1337936.IJ00_27625	8.57e-37	148.0	2CM80@1|root,32SDY@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2151817_1	1347087.CBYO010000017_gene2776	3.279e-65	229.0	COG0500@1|root,COG0500@2|Bacteria,1V4RN@1239|Firmicutes,4HHFD@91061|Bacilli	91061|Bacilli	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
CMS1_k127_2151817_5	697282.Mettu_2792	2.599e-13	81.0	COG1907@1|root,COG1907@2|Bacteria,1MWHM@1224|Proteobacteria,1RQC1@1236|Gammaproteobacteria,1XEBT@135618|Methylococcales	135618|Methylococcales	S	GHMP kinases N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	GHMP_kinases_C,GHMP_kinases_N
CMS1_k127_2151817_3	1487953.JMKF01000075_gene3745	2.521e-53	190.0	COG3651@1|root,COG3651@2|Bacteria,1G6ND@1117|Cyanobacteria,1HBUC@1150|Oscillatoriales	1117|Cyanobacteria	S	protein conserved in bacteria	-	-	-	ko:K09966	-	-	-	-	ko00000	-	-	-	DUF2237
CMS1_k127_2151817_0	309807.SRU_2820	1.883e-89	302.0	COG0116@1|root,COG0116@2|Bacteria,4P49R@976|Bacteroidetes,1FKE7@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	Belongs to the methyltransferase superfamily	-	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
CMS1_k127_2155290_3	1379698.RBG1_1C00001G0855	1.745e-111	385.0	COG0243@1|root,COG0243@2|Bacteria,2NPRJ@2323|unclassified Bacteria	2|Bacteria	C	Molydopterin dinucleotide binding domain	qrcB	-	1.8.5.5	ko:K08352	ko00920,ko01120,map00920,map01120	-	R10149	RC02823	ko00000,ko00001,ko01000,ko02000	5.A.3.5	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CMS1_k127_2155290_5	1379698.RBG1_1C00001G0856	1.424e-80	275.0	COG0437@1|root,COG0437@2|Bacteria,2NNV6@2323|unclassified Bacteria	2|Bacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7
CMS1_k127_2155290_2	1379698.RBG1_1C00001G0857	5.857e-119	400.0	COG5557@1|root,COG5557@2|Bacteria,2NNNQ@2323|unclassified Bacteria	1379698.RBG1_1C00001G0857|-	C	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2155290_16	694429.Pyrfu_1756	3.012e-10	71.0	COG1145@1|root,arCOG02187@2157|Archaea,2XQSW@28889|Crenarchaeota	28889|Crenarchaeota	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4
CMS1_k127_2155290_4	357808.RoseRS_1337	7.836e-84	288.0	COG0330@1|root,COG0330@2|Bacteria,2G5SB@200795|Chloroflexi,375BD@32061|Chloroflexia	32061|Chloroflexia	O	PFAM band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
CMS1_k127_2155290_1	234267.Acid_4435	2.722e-132	447.0	COG3303@1|root,COG3303@2|Bacteria,3Y84F@57723|Acidobacteria	57723|Acidobacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2155290_13	926569.ANT_26960	5.509e-27	121.0	2EH75@1|root,33AYZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2155290_6	357808.RoseRS_1915	2.843e-77	280.0	COG0823@1|root,COG0823@2|Bacteria,2G8PZ@200795|Chloroflexi,377MH@32061|Chloroflexia	32061|Chloroflexia	U	WD40 domain protein beta Propeller	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
CMS1_k127_2155290_14	926550.CLDAP_12410	6.488e-25	109.0	COG2332@1|root,COG2332@2|Bacteria,2G7CS@200795|Chloroflexi	200795|Chloroflexi	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	-	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
CMS1_k127_2155290_0	926569.ANT_19480	2.257e-199	642.0	COG1138@1|root,COG1138@2|Bacteria,2G5SZ@200795|Chloroflexi	200795|Chloroflexi	O	PFAM Cytochrome C assembly protein	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
CMS1_k127_2155290_15	649638.Trad_0412	1.878e-23	106.0	COG3088@1|root,COG3088@2|Bacteria,1WJYG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	subunit of a heme lyase	-	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH
CMS1_k127_2155290_12	926550.CLDAP_40040	1.39e-39	154.0	COG0526@1|root,COG0526@2|Bacteria,2G737@200795|Chloroflexi	200795|Chloroflexi	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,DnaJ
CMS1_k127_2155290_18	1121946.AUAX01000052_gene8144	5.269e-09	64.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,2GJRI@201174|Actinobacteria,4DBEY@85008|Micromonosporales	201174|Actinobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
CMS1_k127_2155290_10	926550.CLDAP_38270	1.11e-59	228.0	COG2010@1|root,COG2010@2|Bacteria,2G741@200795|Chloroflexi	200795|Chloroflexi	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Cytochrome_CBB3
CMS1_k127_2155290_7	926550.CLDAP_12420	1.927e-67	236.0	COG1131@1|root,COG1131@2|Bacteria,2G6IS@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	ccmA	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
CMS1_k127_2155290_8	926569.ANT_19400	1.359e-65	232.0	COG2386@1|root,COG2386@2|Bacteria,2G6TN@200795|Chloroflexi	200795|Chloroflexi	O	PFAM cytochrome c-type biogenesis protein CcmB	ccmB	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
CMS1_k127_2155290_9	522772.Dacet_0330	2.751e-64	228.0	COG0755@1|root,COG0755@2|Bacteria,2GF7F@200930|Deferribacteres	200930|Deferribacteres	O	Cytochrome C assembly protein	-	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
CMS1_k127_2155290_11	66692.ABC1536	1.43e-45	174.0	COG0785@1|root,COG0785@2|Bacteria,1TQH1@1239|Firmicutes,4H9UJ@91061|Bacilli,1ZBPX@1386|Bacillus	91061|Bacilli	O	cytochrome c biogenesis protein	ccdA	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
CMS1_k127_2155290_17	1298863.AUEP01000019_gene3547	8.855e-10	61.0	COG0695@1|root,COG0695@2|Bacteria,2IR0P@201174|Actinobacteria,4DS21@85009|Propionibacteriales	201174|Actinobacteria	O	Glutaredoxin-like domain (DUF836)	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF836
CMS1_k127_2157615_8	926569.ANT_27790	7.097e-23	102.0	COG0375@1|root,COG0500@1|root,COG0375@2|Bacteria,COG2226@2|Bacteria,2G8EN@200795|Chloroflexi	200795|Chloroflexi	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS1_k127_2157615_7	926550.CLDAP_22180	4.757e-29	131.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
CMS1_k127_2157615_3	255470.cbdbA1145	1.376e-122	404.0	COG0592@1|root,COG0592@2|Bacteria,2G641@200795|Chloroflexi,34CUN@301297|Dehalococcoidia	301297|Dehalococcoidia	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
CMS1_k127_2157615_5	1128421.JAGA01000002_gene104	4.037e-95	320.0	COG0598@1|root,COG0598@2|Bacteria,2NQIW@2323|unclassified Bacteria	2|Bacteria	P	CorA-like Mg2+ transporter protein	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
CMS1_k127_2157615_2	518766.Rmar_0699	3.227e-180	571.0	COG0156@1|root,COG0156@2|Bacteria,4NFBU@976|Bacteroidetes,1FIMI@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Aminotransferase class I and II	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS1_k127_2157615_6	880073.Calab_1330	3.747e-58	209.0	COG0204@1|root,COG0204@2|Bacteria	2|Bacteria	I	Acyl-transferase	plsC2	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
CMS1_k127_2157615_4	1192034.CAP_5739	9.617e-120	402.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,42ZJK@68525|delta/epsilon subdivisions,2WV14@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG
CMS1_k127_2157615_0	518766.Rmar_0522	6.924e-231	739.0	COG2217@1|root,COG2217@2|Bacteria,4NERS@976|Bacteroidetes,1FJQW@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	P	haloacid dehalogenase-like hydrolase	-	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,Hydrolase
CMS1_k127_2157615_1	926550.CLDAP_35350	9.599e-197	636.0	COG0751@1|root,COG0752@1|root,COG0751@2|Bacteria,COG0752@2|Bacteria,2G7V0@200795|Chloroflexi	200795|Chloroflexi	J	Glycyl-tRNA synthetase alpha subunit	glyQS	-	6.1.1.14	ko:K14164	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	tRNA-synt_2e,tRNA_synt_2f
CMS1_k127_2166115_4	439235.Dalk_3003	8.211e-44	164.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2WJ4J@28221|Deltaproteobacteria,2MHN2@213118|Desulfobacterales	28221|Deltaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
CMS1_k127_2166115_8	439235.Dalk_3004	1.256e-14	75.0	COG2608@1|root,COG2608@2|Bacteria,1PUDD@1224|Proteobacteria,42XJ7@68525|delta/epsilon subdivisions,2WSKI@28221|Deltaproteobacteria,2MP4U@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Heavy-metal-associated domain	-	-	-	-	-	-	-	-	-	-	-	-	HMA
CMS1_k127_2166115_6	326427.Cagg_3411	6.268e-29	117.0	COG1937@1|root,COG1937@2|Bacteria,2G7H9@200795|Chloroflexi,377N3@32061|Chloroflexia	32061|Chloroflexia	S	Metal-sensitive transcriptional repressor	-	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
CMS1_k127_2166115_1	1128421.JAGA01000003_gene3142	1.015e-122	403.0	COG0758@1|root,COG0758@2|Bacteria,2NP2V@2323|unclassified Bacteria	2|Bacteria	LU	DNA recombination-mediator protein A	dprA	-	5.99.1.2	ko:K03168,ko:K04096	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_processg_A
CMS1_k127_2166115_2	1117108.PAALTS15_06704	4.396e-94	320.0	COG0836@1|root,COG0836@2|Bacteria,1TPC9@1239|Firmicutes,4HDJT@91061|Bacilli,26V7R@186822|Paenibacillaceae	91061|Bacilli	M	Mannose-1-phosphate guanylyltransferase	-	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
CMS1_k127_2166115_0	926569.ANT_15990	7.788e-293	918.0	COG0550@1|root,COG0550@2|Bacteria,2G5ZR@200795|Chloroflexi	200795|Chloroflexi	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
CMS1_k127_2166115_3	1120973.AQXL01000127_gene2725	5.535e-89	306.0	COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,4HAT7@91061|Bacilli,27894@186823|Alicyclobacillaceae	91061|Bacilli	E	Creatinase/Prolidase N-terminal domain	pepP	-	3.4.11.9,3.4.13.9	ko:K01262,ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
CMS1_k127_2166115_5	926569.ANT_15980	4.387e-41	166.0	28T1C@1|root,2ZFAN@2|Bacteria,2G9NB@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2166115_7	1244869.H261_04053	1.103e-25	106.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,2TR3C@28211|Alphaproteobacteria,2JP8K@204441|Rhodospirillales	204441|Rhodospirillales	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
CMS1_k127_2187135_1	1121324.CLIT_2c02290	6.639e-124	417.0	COG0318@1|root,COG0318@2|Bacteria,1UMHB@1239|Firmicutes,25GI8@186801|Clostridia	186801|Clostridia	IQ	GH3 auxin-responsive promoter	-	-	-	-	-	-	-	-	-	-	-	-	GH3
CMS1_k127_2187135_2	1337936.IJ00_18240	5.058e-65	230.0	2DBEV@1|root,2Z8UT@2|Bacteria,1G3XJ@1117|Cyanobacteria,1HJN5@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2187135_0	1121324.CLIT_2c02260	1.946e-124	403.0	COG1032@1|root,COG1032@2|Bacteria,1UYAF@1239|Firmicutes,24D1D@186801|Clostridia	186801|Clostridia	C	PFAM Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
CMS1_k127_2188732_10	1254432.SCE1572_09955	1.405e-20	94.0	28HI5@1|root,2Z7TP@2|Bacteria,1Q2A9@1224|Proteobacteria,437X1@68525|delta/epsilon subdivisions,2X36R@28221|Deltaproteobacteria,2YUJV@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2188732_4	1123508.JH636440_gene2882	4.041e-82	290.0	COG1070@1|root,COG1070@2|Bacteria,2J13I@203682|Planctomycetes	203682|Planctomycetes	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.14	ko:K11214	ko00710,map00710	-	R01844	RC00002,RC00608	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
CMS1_k127_2188732_8	326427.Cagg_0947	1.295e-29	138.0	COG1075@1|root,COG1075@2|Bacteria	2|Bacteria	KLT	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_8,CHAT,PGAP1
CMS1_k127_2188732_6	1382356.JQMP01000003_gene1564	4.111e-64	231.0	COG0407@1|root,COG0407@2|Bacteria,2G6BE@200795|Chloroflexi,27XYH@189775|Thermomicrobia	189775|Thermomicrobia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
CMS1_k127_2188732_0	1009370.ALO_15422	1.27e-172	549.0	COG4948@1|root,COG4948@2|Bacteria,1TS0S@1239|Firmicutes,4H4FY@909932|Negativicutes	909932|Negativicutes	M	mandelate racemase muconate lactonizing	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
CMS1_k127_2188732_2	661478.OP10G_3558	1.159e-102	343.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red,Fer4
CMS1_k127_2188732_3	266117.Rxyl_2686	2.335e-94	326.0	COG3119@1|root,COG3119@2|Bacteria,2H50Z@201174|Actinobacteria,4CRT6@84995|Rubrobacteria	84995|Rubrobacteria	P	PFAM sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS1_k127_2188732_12	1500257.JQNM01000002_gene4370	1.836e-10	68.0	COG1051@1|root,COG1051@2|Bacteria,1N9PU@1224|Proteobacteria,2USNM@28211|Alphaproteobacteria,4BAYD@82115|Rhizobiaceae	28211|Alphaproteobacteria	F	Belongs to the Nudix hydrolase family	mutT	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS1_k127_2188732_5	1532558.JL39_01010	3.501e-70	244.0	COG2186@1|root,COG2186@2|Bacteria,1R3Y8@1224|Proteobacteria,2U215@28211|Alphaproteobacteria,4BBJ2@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
CMS1_k127_2188732_1	1123023.JIAI01000007_gene2009	1.195e-107	356.0	COG5285@1|root,COG5285@2|Bacteria,2HTSH@201174|Actinobacteria,4E5VM@85010|Pseudonocardiales	201174|Actinobacteria	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
CMS1_k127_2188732_9	1122927.KB895428_gene341	2.106e-22	105.0	2DJ9W@1|root,3055C@2|Bacteria,1TXQW@1239|Firmicutes,4I6SC@91061|Bacilli,26UPR@186822|Paenibacillaceae	91061|Bacilli	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS1_k127_2188732_11	324057.Pjdr2_3098	8.087e-18	87.0	2DJ9W@1|root,3055C@2|Bacteria,1TXQW@1239|Firmicutes,4I6SC@91061|Bacilli,26UPR@186822|Paenibacillaceae	91061|Bacilli	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS1_k127_2188732_7	616991.JPOO01000001_gene3096	5.136e-43	160.0	COG1524@1|root,COG1524@2|Bacteria,4NIX9@976|Bacteroidetes,1I94B@117743|Flavobacteriia,23I38@178469|Arenibacter	976|Bacteroidetes	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	3.11.1.2	ko:K19670	ko00440,map00440	-	R00318	RC01309	ko00000,ko00001,ko01000	-	-	-	Phosphodiest
CMS1_k127_2201766_1	926550.CLDAP_30400	4.792e-163	540.0	COG1807@1|root,COG5427@1|root,COG1807@2|Bacteria,COG5427@2|Bacteria,2G5UJ@200795|Chloroflexi	200795|Chloroflexi	M	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2298,PMT_2,TPR_16,TPR_19,TPR_8
CMS1_k127_2201766_7	192952.MM_0178	3.125e-06	59.0	COG0457@1|root,arCOG03038@2157|Archaea,2XUNW@28890|Euryarchaeota,2NAF9@224756|Methanomicrobia	224756|Methanomicrobia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_6,TPR_8
CMS1_k127_2201766_4	1347369.CCAD010000065_gene3815	1.671e-54	196.0	COG0317@1|root,COG0317@2|Bacteria,1VAH0@1239|Firmicutes,4HIPC@91061|Bacilli,1ZG08@1386|Bacillus	91061|Bacilli	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_4
CMS1_k127_2201766_0	926550.CLDAP_09910	3.776e-259	811.0	COG0481@1|root,COG0481@2|Bacteria,2G5K2@200795|Chloroflexi	200795|Chloroflexi	J	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C
CMS1_k127_2201766_6	1499967.BAYZ01000090_gene4936	8.816e-28	129.0	COG0823@1|root,COG0823@2|Bacteria,2NPHZ@2323|unclassified Bacteria	2|Bacteria	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
CMS1_k127_2201766_5	765420.OSCT_2550	4.889e-52	192.0	COG0745@1|root,COG0745@2|Bacteria,2G6A5@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_2201766_2	926569.ANT_10380	5.308e-84	296.0	COG1694@1|root,COG3956@2|Bacteria,2G5WH@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM MazG family protein	-	-	-	ko:K02499	-	-	-	-	ko00000,ko03036	-	-	-	MazG,TP_methylase
CMS1_k127_2201766_3	266117.Rxyl_3165	6.992e-57	212.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2GJBZ@201174|Actinobacteria,4CPHM@84995|Rubrobacteria	84995|Rubrobacteria	S	Belongs to the peptidase M50B family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50
CMS1_k127_2204749_5	926550.CLDAP_04470	5.65e-19	99.0	COG1807@1|root,COG1807@2|Bacteria,2G9RZ@200795|Chloroflexi	200795|Chloroflexi	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2204749_0	717606.PaecuDRAFT_2033	1.324e-122	438.0	COG1361@1|root,COG3291@1|root,COG1361@2|Bacteria,COG3291@2|Bacteria,1UKER@1239|Firmicutes,4HFP1@91061|Bacilli	91061|Bacilli	M	TIGRFAM conserved repeat domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
CMS1_k127_2204749_6	641112.ACOK01000076_gene3030	1.265e-15	93.0	COG4942@1|root,COG4942@2|Bacteria,1TQ5I@1239|Firmicutes,248ZG@186801|Clostridia,3WGCB@541000|Ruminococcaceae	186801|Clostridia	D	Peptidase, M23	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
CMS1_k127_2204749_3	926550.CLDAP_10900	1.597e-56	207.0	COG1376@1|root,COG1388@1|root,COG1376@2|Bacteria,COG1388@2|Bacteria,2G6ZY@200795|Chloroflexi	200795|Chloroflexi	M	PFAM ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	LysM,YkuD
CMS1_k127_2204749_4	324602.Caur_3114	2.543e-35	141.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS1_k127_2204749_1	926550.CLDAP_13320	4.434e-88	302.0	COG1609@1|root,COG1609@2|Bacteria,2G7SU@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
CMS1_k127_2204749_2	926550.CLDAP_10200	2.557e-82	280.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
CMS1_k127_2217738_2	161156.JQKW01000012_gene43	1.822e-15	79.0	COG0500@1|root,COG2226@2|Bacteria,2GIQ1@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
CMS1_k127_2217738_3	1227488.C477_00970	0.0004237	48.0	COG1266@1|root,arCOG02768@2157|Archaea,2XXDG@28890|Euryarchaeota,23VZI@183963|Halobacteria	183963|Halobacteria	S	metal-dependent membrane protease	-	-	-	-	-	-	-	-	-	-	-	-	Abi
CMS1_k127_2217738_1	525904.Tter_0491	1.625e-24	103.0	COG0566@1|root,COG0566@2|Bacteria,2NQ0F@2323|unclassified Bacteria	2|Bacteria	J	tRNA rRNA methyltransferase	spoU	-	2.1.1.185,2.1.1.34	ko:K00556,ko:K03218,ko:K03437	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	SpoU_methylase
CMS1_k127_2217738_0	32057.KB217478_gene7188	2.064e-115	383.0	COG3408@1|root,COG3408@2|Bacteria,1G2AS@1117|Cyanobacteria	1117|Cyanobacteria	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N
CMS1_k127_2218881_8	926550.CLDAP_27100	2.452e-37	143.0	COG0434@1|root,COG0434@2|Bacteria,2G6UF@200795|Chloroflexi	200795|Chloroflexi	S	PFAM photosystem I assembly BtpA	-	-	-	ko:K06971	-	-	-	-	ko00000	-	-	-	BtpA
CMS1_k127_2218881_0	416591.Tlet_1423	1.645e-165	536.0	COG1070@1|root,COG1070@2|Bacteria,2GCEX@200918|Thermotogae	200918|Thermotogae	G	Belongs to the FGGY kinase family	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
CMS1_k127_2218881_5	1379698.RBG1_1C00001G0560	8.061e-78	268.0	COG0483@1|root,COG0483@2|Bacteria,2NP94@2323|unclassified Bacteria	2|Bacteria	G	Inositol monophosphatase	suhB	GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616	3.1.3.25,3.1.3.7	ko:K01082,ko:K01092	ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070	M00131	R00188,R00508,R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	Inositol_P
CMS1_k127_2218881_1	1123023.JIAI01000001_gene7299	1.937e-163	523.0	COG4948@1|root,COG4948@2|Bacteria,2I8X2@201174|Actinobacteria,4E9HY@85010|Pseudonocardiales	201174|Actinobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	rhmD	-	4.2.1.90	ko:K12661	ko00051,ko01120,map00051,map01120	-	R03774	RC00543	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
CMS1_k127_2218881_7	1134445.AJJM01000054_gene2233	2.907e-40	160.0	COG2362@1|root,COG2362@2|Bacteria,2GK6A@201174|Actinobacteria	201174|Actinobacteria	E	D-aminopeptidase	-	-	-	ko:K16203	-	-	-	-	ko00000,ko01000,ko01002	3.A.1.5.2	-	-	Peptidase_M55
CMS1_k127_2218881_2	926569.ANT_26670	2.969e-155	509.0	COG0459@1|root,COG0459@2|Bacteria,2G65N@200795|Chloroflexi	200795|Chloroflexi	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
CMS1_k127_2218881_4	525904.Tter_2317	7.505e-80	278.0	COG0395@1|root,COG0395@2|Bacteria	2|Bacteria	P	glycerophosphodiester transmembrane transport	-	-	-	ko:K02026,ko:K05815	ko02010,map02010	M00198,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.3	-	-	BPD_transp_1
CMS1_k127_2218881_3	525904.Tter_2523	3.175e-98	330.0	COG1175@1|root,COG1175@2|Bacteria,2NQCB@2323|unclassified Bacteria	2|Bacteria	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025,ko:K05814,ko:K10118,ko:K10237,ko:K10241,ko:K15771,ko:K17235,ko:K17316	ko02010,map02010	M00196,M00198,M00204,M00206,M00207,M00491,M00602,M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.17,3.A.1.1.2,3.A.1.1.23,3.A.1.1.24,3.A.1.1.28,3.A.1.1.3,3.A.1.1.30,3.A.1.1.34	-	-	BPD_transp_1
CMS1_k127_2218881_9	1380391.JIAS01000012_gene3961	3.728e-28	129.0	COG1653@1|root,COG1653@2|Bacteria,1PHMZ@1224|Proteobacteria,2V8PA@28211|Alphaproteobacteria,2JXKB@204441|Rhodospirillales	204441|Rhodospirillales	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1
CMS1_k127_2218881_6	926550.CLDAP_17850	4.839e-55	200.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	mshD	-	2.3.1.189	ko:K15520	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
CMS1_k127_2223758_2	479434.Sthe_3413	1.956e-154	496.0	COG1032@1|root,COG1032@2|Bacteria,2G6ZI@200795|Chloroflexi	200795|Chloroflexi	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
CMS1_k127_2223758_3	1535287.JP74_03050	1.504e-101	341.0	COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,2TR4Y@28211|Alphaproteobacteria,3N64F@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prsA	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran,Pribosyltran_N
CMS1_k127_2223758_0	479434.Sthe_3412	5.023e-183	584.0	COG1032@1|root,COG1032@2|Bacteria,2G6ZI@200795|Chloroflexi	200795|Chloroflexi	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
CMS1_k127_2223758_1	1123075.AUDP01000004_gene751	6.384e-169	542.0	COG3119@1|root,COG3119@2|Bacteria,1TQEP@1239|Firmicutes,2482B@186801|Clostridia,3WJZB@541000|Ruminococcaceae	186801|Clostridia	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS1_k127_2223758_4	1321778.HMPREF1982_02329	4.295e-29	123.0	COG0500@1|root,COG2226@2|Bacteria,1TSBS@1239|Firmicutes,253MR@186801|Clostridia	186801|Clostridia	Q	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2224877_3	926569.ANT_21940	2.541e-21	97.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114	-	ko:K15876	ko00910,ko01120,map00910,map01120	M00530	R05712	RC00176	ko00000,ko00001,ko00002	-	-	-	Cytochrom_NNT,Cytochrom_c3_2
CMS1_k127_2224877_0	756499.Desde_4095	3.595e-132	436.0	COG1600@1|root,COG1600@2|Bacteria,1V0B5@1239|Firmicutes,24FDD@186801|Clostridia,262G9@186807|Peptococcaceae	186801|Clostridia	C	TIGRFAM reductive dehalogenase	-	-	-	-	-	-	-	-	-	-	-	-	Dehalogenase,Fer4_16
CMS1_k127_2224877_1	1382306.JNIM01000001_gene1045	6.742e-58	208.0	COG2197@1|root,COG2197@2|Bacteria,2G6PA@200795|Chloroflexi	200795|Chloroflexi	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS1_k127_2224877_2	926550.CLDAP_25550	2.331e-45	183.0	COG2203@1|root,COG4585@1|root,COG5002@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,COG5002@2|Bacteria,2G8PE@200795|Chloroflexi	200795|Chloroflexi	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
CMS1_k127_2224877_4	443144.GM21_1714	7.915e-13	76.0	COG3322@1|root,COG3322@2|Bacteria,1REX0@1224|Proteobacteria	1224|Proteobacteria	T	CHASE4 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2231006_11	3847.GLYMA03G31111.1	1.357e-11	69.0	2CKJS@1|root,2QQN6@2759|Eukaryota,37RTC@33090|Viridiplantae,3G8Z6@35493|Streptophyta,4JHPB@91835|fabids	35493|Streptophyta	S	Belongs to the terpene synthase family	CPS1	GO:0000287,GO:0001101,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006720,GO:0006721,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009507,GO:0009536,GO:0009685,GO:0009686,GO:0009719,GO:0009725,GO:0009739,GO:0009740,GO:0009755,GO:0009905,GO:0009987,GO:0010033,GO:0010476,GO:0010817,GO:0016053,GO:0016101,GO:0016102,GO:0016114,GO:0016853,GO:0016872,GO:0019752,GO:0023052,GO:0032870,GO:0033993,GO:0042221,GO:0042445,GO:0042446,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0065008,GO:0070887,GO:0071229,GO:0071310,GO:0071370,GO:0071396,GO:0071495,GO:0071704,GO:1901576,GO:1901700,GO:1901701	5.5.1.13,5.5.1.14	ko:K04120,ko:K14043	ko00904,ko01100,ko01110,map00904,map01100,map01110	-	R02068,R06312	RC00642	ko00000,ko00001,ko01000	-	-	-	Terpene_synth,Terpene_synth_C
CMS1_k127_2231006_10	44689.DDB0231668	2.97e-13	79.0	28XHJ@1|root,2RC2G@2759|Eukaryota,3XAAT@554915|Amoebozoa	554915|Amoebozoa	S	transferase activity, transferring alkyl or aryl (other than methyl) groups	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2231006_8	289376.THEYE_A1018	9.068e-26	111.0	COG1765@1|root,COG1765@2|Bacteria	2|Bacteria	O	OsmC-like protein	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
CMS1_k127_2231006_1	926550.CLDAP_34720	1.228e-136	451.0	COG0260@1|root,COG0260@2|Bacteria,2G617@200795|Chloroflexi	200795|Chloroflexi	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
CMS1_k127_2231006_5	316274.Haur_3775	3.93e-78	278.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G88D@200795|Chloroflexi,374V1@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA_3
CMS1_k127_2231006_2	926550.CLDAP_29840	4.711e-111	388.0	COG3023@1|root,COG4423@1|root,COG3023@2|Bacteria,COG4423@2|Bacteria	2|Bacteria	S	positive regulation of growth	-	-	-	ko:K19687	-	-	-	-	ko00000,ko02048	-	-	-	Amidase_2,PG_binding_1,PSK_trans_fac
CMS1_k127_2231006_7	357808.RoseRS_0194	6.128e-44	170.0	COG1354@1|root,COG1354@2|Bacteria,2G6WU@200795|Chloroflexi,375MQ@32061|Chloroflexia	32061|Chloroflexia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
CMS1_k127_2231006_4	82654.Pse7367_1031	1.468e-80	276.0	2EU2Z@1|root,33MJU@2|Bacteria	2|Bacteria	H	Ribosomal RNA methyltransferase (FmrO)	-	-	2.1.1.179	ko:K18845	-	-	-	-	br01600,ko00000,ko01000,ko01504,ko03009	-	-	-	FmrO
CMS1_k127_2231006_0	357808.RoseRS_1988	2.995e-157	503.0	COG0343@1|root,COG0343@2|Bacteria,2G87H@200795|Chloroflexi,376RX@32061|Chloroflexia	32061|Chloroflexia	J	TIGRFAM tRNA-guanine transglycosylase, various specificities	-	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
CMS1_k127_2231006_3	926550.CLDAP_31760	4.13e-105	344.0	COG0313@1|root,COG0313@2|Bacteria,2G5VQ@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
CMS1_k127_2231006_9	909663.KI867150_gene1560	3.568e-19	92.0	COG5652@1|root,COG5652@2|Bacteria,1PUUC@1224|Proteobacteria,43F3B@68525|delta/epsilon subdivisions,2X381@28221|Deltaproteobacteria,2MSC7@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
CMS1_k127_2231006_6	357808.RoseRS_4448	6.317e-73	260.0	COG0438@1|root,COG0438@2|Bacteria,2G713@200795|Chloroflexi,37525@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glycos_transf_1
CMS1_k127_2266978_2	221288.JH992901_gene3915	1.713e-152	494.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1JI65@1189|Stigonemataceae	1117|Cyanobacteria	Q	Condensation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,NAD_binding_4,PP-binding,TPR_1,TPR_8,Thioesterase
CMS1_k127_2266978_1	1173024.KI912151_gene1773	1.223e-232	755.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1JKTF@1189|Stigonemataceae	1117|Cyanobacteria	Q	Thioesterase domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,PilZ,Thioesterase
CMS1_k127_2266978_0	926550.CLDAP_36250	4.246e-242	758.0	COG1032@1|root,COG1032@2|Bacteria,2G5SI@200795|Chloroflexi	200795|Chloroflexi	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
CMS1_k127_2266978_3	324602.Caur_3779	9.857e-129	424.0	COG0463@1|root,COG0463@2|Bacteria,2G7KQ@200795|Chloroflexi,376XJ@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS1_k127_2266978_4	926550.CLDAP_36270	1.305e-83	284.0	COG0110@1|root,COG0110@2|Bacteria,2G6D2@200795|Chloroflexi	200795|Chloroflexi	S	PFAM transferase hexapeptide repeat containing protein	-	-	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2
CMS1_k127_2266978_5	357808.RoseRS_4218	9.377e-50	185.0	COG0241@1|root,COG0241@2|Bacteria,2G6V8@200795|Chloroflexi,375WG@32061|Chloroflexia	32061|Chloroflexia	E	TIGRFAM histidinol-phosphate phosphatase family protein	-	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like
CMS1_k127_2276162_5	1192034.CAP_8276	4.537e-40	165.0	COG1520@1|root,COG3055@1|root,COG1520@2|Bacteria,COG3055@2|Bacteria,1R0E4@1224|Proteobacteria,43EEC@68525|delta/epsilon subdivisions,2X84M@28221|Deltaproteobacteria,2YUU3@29|Myxococcales	28221|Deltaproteobacteria	S	FG-GAP repeat	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP_2
CMS1_k127_2276162_8	1535287.JP74_13065	1.094e-05	48.0	COG4875@1|root,COG4875@2|Bacteria,1N89Y@1224|Proteobacteria,2UKHR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2,SnoaL_3
CMS1_k127_2276162_0	1037409.BJ6T_59690	2.124e-102	353.0	COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,2TS56@28211|Alphaproteobacteria,3JRE9@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	J	Belongs to the amidase family	-	-	3.5.1.4,6.3.5.6,6.3.5.7	ko:K01426,ko:K02433	ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120	-	R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
CMS1_k127_2276162_4	1121936.AUHI01000006_gene2064	1.854e-59	211.0	COG2320@1|root,COG2320@2|Bacteria,1V3IB@1239|Firmicutes,4HH5X@91061|Bacilli	91061|Bacilli	K	GrpB protein	-	-	-	-	-	-	-	-	-	-	-	-	GrpB
CMS1_k127_2276162_3	56107.Cylst_0009	1.04e-72	261.0	COG1020@1|root,COG1020@2|Bacteria,1G2QF@1117|Cyanobacteria,1HIRK@1161|Nostocales	1117|Cyanobacteria	Q	protein containing a NRPS condensation (Elongation) domain	-	-	-	-	-	-	-	-	-	-	-	-	Condensation
CMS1_k127_2276162_7	40571.JOEA01000007_gene6542	6.922e-15	82.0	COG1670@1|root,COG1670@2|Bacteria,2IFMK@201174|Actinobacteria,4E3F3@85010|Pseudonocardiales	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.57,2.3.1.82	ko:K00657,ko:K00663	ko00330,ko01100,ko04216,map00330,map01100,map04216	M00135	R01154	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Acetyltransf_1,Acetyltransf_3,Acetyltransf_8
CMS1_k127_2276162_2	485913.Krac_12381	8.301e-83	286.0	COG2378@1|root,COG2378@2|Bacteria	2|Bacteria	K	regulation of single-species biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
CMS1_k127_2276162_6	452637.Oter_0019	2.149e-30	126.0	COG3449@1|root,COG3449@2|Bacteria	2|Bacteria	K	DNA topoisomerase (ATP-hydrolyzing) inhibitor activity	-	-	-	ko:K13652,ko:K13653	-	-	-	-	ko00000,ko03000	-	-	-	Cass2,GyrI-like,HTH_18
CMS1_k127_2276162_1	485913.Krac_4187	1.11e-91	310.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
CMS1_k127_2279848_3	1499967.BAYZ01000041_gene2356	1.794e-50	195.0	COG3356@1|root,COG3356@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
CMS1_k127_2279848_1	1121422.AUMW01000013_gene1457	4.811e-81	279.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,260U6@186807|Peptococcaceae	186801|Clostridia	EP	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
CMS1_k127_2279848_0	504728.K649_15350	4.441e-99	332.0	COG0601@1|root,COG0601@2|Bacteria,1WJIM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_2279848_2	867903.ThesuDRAFT_01386	4.029e-70	259.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,248A3@186801|Clostridia,3WCXU@538999|Clostridiales incertae sedis	186801|Clostridia	E	PFAM Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_2279848_7	1265310.CCBD010000077_gene5358	2.817e-11	70.0	2ATIW@1|root,31J2W@2|Bacteria,2IITC@201174|Actinobacteria,239TF@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2279848_4	1173021.ALWA01000035_gene3793	7.716e-49	181.0	COG1309@1|root,COG1309@2|Bacteria,1GBVU@1117|Cyanobacteria	1117|Cyanobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS1_k127_2279848_5	1121904.ARBP01000006_gene3963	5.085e-38	145.0	2B1RZ@1|root,31U7Q@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_228860_2	42256.RradSPS_0358	8.863e-49	181.0	COG2909@1|root,COG2909@2|Bacteria,2HENR@201174|Actinobacteria,4CPC9@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,AAA_22,GerE
CMS1_k127_228860_4	47839.CCAU010000006_gene70	3.755e-10	69.0	COG1357@1|root,COG1357@2|Bacteria,2HSFH@201174|Actinobacteria,23BRI@1762|Mycobacteriaceae	201174|Actinobacteria	S	Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
CMS1_k127_228860_1	68260.JOAY01000013_gene2817	2.333e-151	491.0	COG0596@1|root,COG0596@2|Bacteria,2GK03@201174|Actinobacteria	201174|Actinobacteria	L	Alpha beta hydrolase	pip	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
CMS1_k127_228860_0	1047013.AQSP01000142_gene240	5.206e-265	829.0	COG3533@1|root,COG3533@2|Bacteria,2NNW0@2323|unclassified Bacteria	2|Bacteria	S	Beta-L-arabinofuranosidase, GH127	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	F5_F8_type_C,Glyco_hydro_127
CMS1_k127_228860_3	66377.JOBH01000002_gene956	3.708e-31	125.0	COG3118@1|root,COG3118@2|Bacteria,2I35R@201174|Actinobacteria	201174|Actinobacteria	O	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotran_2,Arylsulfotrans
CMS1_k127_2314502_2	521011.Mpal_0423	3.829e-90	312.0	COG3391@1|root,arCOG02516@1|root,arCOG02516@2157|Archaea,arCOG03563@2157|Archaea,2Y7Y4@28890|Euryarchaeota,2NBN4@224756|Methanomicrobia	2157|Archaea	S	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,HemolysinCabind,Kelch_4,NHL,PKD
CMS1_k127_2314502_0	247490.KSU1_C0202	2.488e-123	402.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	hflC	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Band_7
CMS1_k127_2314502_3	1294142.CINTURNW_0549	2.578e-22	110.0	COG0477@1|root,COG2814@2|Bacteria,1UZKT@1239|Firmicutes,25EHZ@186801|Clostridia,36HPP@31979|Clostridiaceae	186801|Clostridia	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_2314502_1	1288963.ADIS_0475	2.252e-99	334.0	28KEJ@1|root,2Z9XE@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2317415_3	383372.Rcas_3448	7.879e-100	330.0	COG0123@1|root,COG0123@2|Bacteria,2G89I@200795|Chloroflexi,376ST@32061|Chloroflexia	32061|Chloroflexia	BQ	PFAM histone deacetylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
CMS1_k127_2317415_6	391612.CY0110_13726	3.093e-07	52.0	COG0667@1|root,COG0667@2|Bacteria,1G1PP@1117|Cyanobacteria,3KFWJ@43988|Cyanothece	1117|Cyanobacteria	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS1_k127_2317415_1	1382356.JQMP01000003_gene2001	6.324e-110	373.0	COG1167@1|root,COG1167@2|Bacteria,2G5XE@200795|Chloroflexi,27Y0D@189775|Thermomicrobia	189775|Thermomicrobia	EK	Alanine-glyoxylate amino-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
CMS1_k127_2317415_7	2045.KR76_19170	0.0009736	50.0	COG2510@1|root,COG2510@2|Bacteria,2HW2A@201174|Actinobacteria,4DUJ8@85009|Propionibacteriales	201174|Actinobacteria	S	EamA-like transporter family	-	-	-	ko:K08978	-	-	-	-	ko00000,ko02000	2.A.7.2	-	-	EamA
CMS1_k127_2317415_2	670487.Ocepr_0388	9.955e-106	352.0	COG1171@1|root,COG1171@2|Bacteria,1WI3F@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS1_k127_2317415_4	309801.trd_0073	3.779e-96	331.0	COG2234@1|root,COG2234@2|Bacteria,2G9MK@200795|Chloroflexi,27XKJ@189775|Thermomicrobia	189775|Thermomicrobia	S	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
CMS1_k127_2317415_0	926569.ANT_01650	1.318e-154	492.0	COG0214@1|root,COG0214@2|Bacteria,2G5MW@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	-	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
CMS1_k127_2317415_5	1123322.KB904678_gene3183	1.12e-15	80.0	2AAWD@1|root,3109H@2|Bacteria,2IG0D@201174|Actinobacteria	201174|Actinobacteria	S	Alkylmercury lyase	-	-	-	-	-	-	-	-	-	-	-	-	MerB
CMS1_k127_231963_2	485913.Krac_8024	2.18e-21	97.0	COG0442@1|root,COG0442@2|Bacteria,2G5Q6@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
CMS1_k127_231963_0	266117.Rxyl_2590	1.055e-158	510.0	COG2721@1|root,COG2721@2|Bacteria,2GJC8@201174|Actinobacteria	201174|Actinobacteria	G	D-galactarate dehydratase Altronate	-	-	4.4.1.24	ko:K16846	ko00270,map00270	-	R07633	RC01785	ko00000,ko00001,ko01000	-	-	-	GD_AH_C
CMS1_k127_231963_1	397948.Cmaq_1141	4.695e-23	102.0	COG2721@1|root,arCOG05318@2157|Archaea,2XSB7@28889|Crenarchaeota	28889|Crenarchaeota	G	SAF	-	-	4.4.1.24	ko:K16845	ko00270,map00270	-	R07633	RC01785	ko00000,ko00001,ko01000	-	-	-	SAF
CMS1_k127_2322219_2	926550.CLDAP_10530	5.06e-58	224.0	COG0457@1|root,COG0823@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,2G8PZ@200795|Chloroflexi	200795|Chloroflexi	U	WD40 domain protein beta Propeller	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
CMS1_k127_2322219_4	1033734.CAET01000079_gene3557	5.697e-09	61.0	29S70@1|root,30DBH@2|Bacteria,1UB40@1239|Firmicutes,4IMGK@91061|Bacilli,1ZK45@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2322219_3	868864.Dester_1469	1.669e-13	80.0	COG0468@1|root,COG0468@2|Bacteria,2G3UK@200783|Aquificae	200783|Aquificae	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
CMS1_k127_2322219_1	1117108.PAALTS15_01607	1.056e-69	241.0	COG1713@1|root,COG1713@2|Bacteria,1V44H@1239|Firmicutes,4HH8H@91061|Bacilli,26VP4@186822|Paenibacillaceae	91061|Bacilli	H	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
CMS1_k127_2322219_5	1227457.C451_18773	0.0007961	48.0	arCOG03392@1|root,arCOG03392@2157|Archaea,2XYTK@28890|Euryarchaeota,23WQS@183963|Halobacteria	183963|Halobacteria	S	Membrane-bound metal-dependent hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	YdjM
CMS1_k127_2322219_0	272123.Anacy_4978	8.206e-70	245.0	COG2931@1|root,COG3211@1|root,COG2931@2|Bacteria,COG3211@2|Bacteria,1GIZZ@1117|Cyanobacteria,1HJZZ@1161|Nostocales	1117|Cyanobacteria	Q	Bacterial protein of unknown function (DUF839)	-	-	-	-	-	-	-	-	-	-	-	-	DUF839
CMS1_k127_2336586_4	552811.Dehly_0125	7.579e-13	77.0	COG1579@1|root,COG1579@2|Bacteria,2G775@200795|Chloroflexi,34D9U@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Zn-ribbon protein possibly nucleic acid-binding	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
CMS1_k127_2336586_5	679197.HMPREF9336_00335	4.811e-09	67.0	COG1652@1|root,COG1652@2|Bacteria,2IAZ9@201174|Actinobacteria	201174|Actinobacteria	S	Bulb-type mannose-specific lectin	-	-	-	-	-	-	-	-	-	-	-	-	B_lectin,LysM
CMS1_k127_2336586_3	661478.OP10G_4733	8.646e-32	136.0	COG3023@1|root,COG3023@2|Bacteria	2|Bacteria	V	N-Acetylmuramoyl-L-alanine amidase	ampD	-	3.5.1.28	ko:K01447,ko:K03806,ko:K11066	-	-	R04112	RC00064,RC00141	ko00000,ko01000,ko01011	-	-	-	Amidase_2,PG_binding_1,SH3_3
CMS1_k127_2336586_2	869210.Marky_2237	1.878e-46	174.0	COG2059@1|root,COG2059@2|Bacteria,1WKSK@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	COG2059 Chromate transport protein ChrA	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
CMS1_k127_2336586_1	316274.Haur_1458	5.062e-141	496.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2G699@200795|Chloroflexi,3766E@32061|Chloroflexia	32061|Chloroflexia	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Guanylate_cyc,TPR_12
CMS1_k127_2336586_0	879212.DespoDRAFT_03206	5.021e-270	852.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria,2MHRD@213118|Desulfobacterales	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
CMS1_k127_2351616_1	1123258.AQXZ01000015_gene4504	5.69e-06	59.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT,PMT_2
CMS1_k127_2351616_0	926566.Terro_1717	7.691e-15	88.0	COG1269@1|root,COG1269@2|Bacteria	2|Bacteria	C	ATP hydrolysis coupled proton transport	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS1_k127_2352529_4	1210884.HG799464_gene11111	8.341e-35	136.0	COG1402@1|root,COG1402@2|Bacteria,2IYP1@203682|Planctomycetes	203682|Planctomycetes	S	Creatinine amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Creatininase
CMS1_k127_2352529_3	1173027.Mic7113_6060	3.256e-45	168.0	2CFUA@1|root,32S2G@2|Bacteria,1G7BR@1117|Cyanobacteria,1HBHX@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2352529_5	379066.GAU_3713	2.258e-29	120.0	COG2944@1|root,COG2944@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	ko:K07726	-	-	-	-	ko00000,ko03000	-	-	-	Fer4,HTH_3,HTH_31
CMS1_k127_2352529_6	257310.BB2743	1.096e-28	117.0	COG4737@1|root,COG4737@2|Bacteria,1N7N5@1224|Proteobacteria,2VXKF@28216|Betaproteobacteria,3T4JG@506|Alcaligenaceae	28216|Betaproteobacteria	S	RelE toxin of RelE / RelB toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	RelE
CMS1_k127_2352529_7	292459.STH1763	1.065e-09	66.0	COG3557@1|root,COG3557@2|Bacteria,1VC3B@1239|Firmicutes	1239|Firmicutes	J	Protein of unknown function (DUF402)	-	-	-	ko:K07586	-	-	-	-	ko00000	-	-	-	DUF402
CMS1_k127_2352529_1	1449049.JONW01000001_gene3326	5.076e-50	188.0	COG0596@1|root,COG0596@2|Bacteria,1NZXA@1224|Proteobacteria,2TY7X@28211|Alphaproteobacteria,2KJGA@204458|Caulobacterales	204458|Caulobacterales	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CMS1_k127_2352529_0	1120950.KB892708_gene4442	1.096e-52	192.0	2AWUY@1|root,31NS8@2|Bacteria,2IPXS@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2352529_2	714943.Mucpa_1505	2.102e-46	181.0	COG5433@1|root,COG5433@2|Bacteria,4NHJC@976|Bacteroidetes,1IPH8@117747|Sphingobacteriia	976|Bacteroidetes	L	PFAM Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
CMS1_k127_2353938_0	1242864.D187_000281	4.857e-44	181.0	COG1957@1|root,COG1957@2|Bacteria,1MUIW@1224|Proteobacteria,42WQU@68525|delta/epsilon subdivisions,2WTEH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Inosine-uridine preferring nucleoside hydrolase	-	-	3.2.2.1	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
CMS1_k127_2353938_1	931627.MycrhDRAFT_5311	0.0001992	50.0	COG2020@1|root,COG2020@2|Bacteria,2I4HM@201174|Actinobacteria,23314@1762|Mycobacteriaceae	201174|Actinobacteria	O	PFAM Isoprenylcysteine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
CMS1_k127_2359782_3	710696.Intca_0555	4.18e-05	49.0	COG3255@1|root,COG3255@2|Bacteria,2IFWK@201174|Actinobacteria,4FJIS@85021|Intrasporangiaceae	201174|Actinobacteria	I	Alkyl sulfatase C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
CMS1_k127_2359782_4	643473.KB235930_gene523	0.0001133	44.0	COG2402@1|root,COG2402@2|Bacteria,1G6FH@1117|Cyanobacteria,1HSJJ@1161|Nostocales	1117|Cyanobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
CMS1_k127_2359782_1	926550.CLDAP_31390	4.724e-115	391.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria	926550.CLDAP_31390|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2359782_2	926550.CLDAP_19610	4.015e-56	207.0	COG0589@1|root,COG0589@2|Bacteria,2GBJZ@200795|Chloroflexi	200795|Chloroflexi	T	response to stress	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS1_k127_2359782_0	479434.Sthe_2668	9.913e-181	579.0	COG4447@1|root,COG4447@2|Bacteria,2G678@200795|Chloroflexi,27YSS@189775|Thermomicrobia	189775|Thermomicrobia	S	PFAM glycosyl hydrolase BNR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CMS1_k127_2361246_0	926569.ANT_08530	1.862e-127	414.0	COG1087@1|root,COG1087@2|Bacteria,2G8A8@200795|Chloroflexi	200795|Chloroflexi	M	NAD(P)H-binding	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
CMS1_k127_2361246_2	1128421.JAGA01000002_gene967	2.435e-103	351.0	COG2211@1|root,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_2361246_6	644966.Tmar_0612	1.036e-46	173.0	COG2236@1|root,COG2236@2|Bacteria,1W2U7@1239|Firmicutes,24W36@186801|Clostridia	186801|Clostridia	F	PFAM Phosphoribosyl transferase domain	-	-	-	ko:K07101	-	-	-	-	ko00000	-	-	-	Pribosyltran
CMS1_k127_2361246_4	926569.ANT_19030	8.495e-58	207.0	COG2220@1|root,COG2220@2|Bacteria,2G6IQ@200795|Chloroflexi	200795|Chloroflexi	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
CMS1_k127_2361246_11	944480.ATUV01000001_gene1660	6.771e-14	81.0	COG0457@1|root,COG0457@2|Bacteria,1PFUI@1224|Proteobacteria,42W2K@68525|delta/epsilon subdivisions,2WRN3@28221|Deltaproteobacteria,2M7CH@213113|Desulfurellales	28221|Deltaproteobacteria	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_19,TPR_8
CMS1_k127_2361246_7	511051.CSE_02410	9.3e-39	168.0	COG1361@1|root,COG3210@1|root,COG4719@1|root,COG1361@2|Bacteria,COG3210@2|Bacteria,COG4719@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11
CMS1_k127_2361246_15	1485545.JQLW01000005_gene868	0.0005402	53.0	COG2831@1|root,COG2831@2|Bacteria,1MWWH@1224|Proteobacteria	1224|Proteobacteria	U	PFAM Ig domain protein, group 1 domain protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_1
CMS1_k127_2361246_8	260799.BAS3452	8.97e-33	149.0	COG1361@1|root,COG1361@2|Bacteria,1V4V3@1239|Firmicutes,4HUG3@91061|Bacilli,1ZPVB@1386|Bacillus	91061|Bacilli	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,WxL
CMS1_k127_2361246_12	383372.Rcas_2841	1.351e-09	73.0	COG1572@1|root,COG1572@2|Bacteria,2G83M@200795|Chloroflexi,377MG@32061|Chloroflexia	32061|Chloroflexia	Q	CARDB	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Chlam_PMP,DUF1573
CMS1_k127_2361246_16	1443122.Z958_08760	0.0009807	51.0	COG1361@1|root,COG1361@2|Bacteria,1V4V3@1239|Firmicutes	1239|Firmicutes	M	TIGRFAM conserved repeat domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
CMS1_k127_2361246_1	309801.trd_1505	1.112e-104	354.0	COG0612@1|root,COG0612@2|Bacteria,2G672@200795|Chloroflexi,27XSH@189775|Thermomicrobia	189775|Thermomicrobia	S	Belongs to the peptidase M16 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
CMS1_k127_2361246_3	926550.CLDAP_31840	5.953e-69	245.0	COG0491@1|root,COG0491@2|Bacteria,2G93C@200795|Chloroflexi	200795|Chloroflexi	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS1_k127_2361246_9	449447.MAE_24760	4.806e-31	126.0	2CRVT@1|root,32SPS@2|Bacteria,1G7NK@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2361246_10	449447.MAE_24750	2.271e-16	83.0	COG1403@1|root,COG1403@2|Bacteria,1G6DP@1117|Cyanobacteria	1117|Cyanobacteria	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH,HNH_5
CMS1_k127_2361246_5	1283300.ATXB01000002_gene3078	1.022e-50	189.0	COG2202@1|root,COG2208@1|root,COG3290@1|root,COG3829@1|root,COG2202@2|Bacteria,COG2208@2|Bacteria,COG3290@2|Bacteria,COG3829@2|Bacteria,1RGZF@1224|Proteobacteria,1S6GG@1236|Gammaproteobacteria,1XDM4@135618|Methylococcales	135618|Methylococcales	KT	PFAM Stage II sporulation protein E (SpoIIE)	-	-	-	-	-	-	-	-	-	-	-	-	PAS_9,SpoIIE
CMS1_k127_236142_1	485913.Krac_3297	2.516e-98	326.0	COG1028@1|root,COG1028@2|Bacteria,2G85A@200795|Chloroflexi	200795|Chloroflexi	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS1_k127_236142_0	485913.Krac_3296	3.081e-151	490.0	COG0809@1|root,COG0809@2|Bacteria,2G7UA@200795|Chloroflexi	200795|Chloroflexi	H	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	-	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
CMS1_k127_236142_2	765420.OSCT_0523	9.226e-51	194.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2G790@200795|Chloroflexi,3750C@32061|Chloroflexia	32061|Chloroflexia	T	SMART protein phosphatase 2C domain protein	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_2,GAF_3,SpoIIE
CMS1_k127_2367417_1	926550.CLDAP_29150	4.306e-65	229.0	COG1960@1|root,COG1960@2|Bacteria,2G5K3@200795|Chloroflexi	200795|Chloroflexi	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS1_k127_2367417_0	931276.Cspa_c18740	1.391e-160	527.0	COG0480@1|root,COG0480@2|Bacteria,1TPQH@1239|Firmicutes,247X4@186801|Clostridia,36DHY@31979|Clostridiaceae	186801|Clostridia	J	elongation factor G	-	-	-	ko:K18220	-	-	-	-	br01600,ko00000,ko01504	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
CMS1_k127_2367417_3	316274.Haur_1271	7.69e-22	100.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HATPase_c,Response_reg
CMS1_k127_2367417_2	357808.RoseRS_0204	5.436e-64	235.0	COG0745@1|root,COG2199@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.7.13.3	ko:K03407,ko:K07678	ko02020,ko02025,ko02026,ko02030,ko05111,map02020,map02025,map02026,map02030,map05111	M00475,M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CHASE3,GAF_3,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_7,PAS_8,PAS_9,Response_reg
CMS1_k127_2381292_1	1283299.AUKG01000001_gene2841	0.0006705	49.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS1_k127_2381292_0	574375.BAGA_21765	2.235e-58	208.0	COG1051@1|root,COG1051@2|Bacteria,1VVIT@1239|Firmicutes,4HWSQ@91061|Bacilli,1ZFXQ@1386|Bacillus	91061|Bacilli	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS1_k127_2391816_5	1382306.JNIM01000001_gene1224	1.048e-36	143.0	COG1109@1|root,COG1208@1|root,COG1109@2|Bacteria,COG1208@2|Bacteria,2G65W@200795|Chloroflexi	200795|Chloroflexi	M	PFAM transferase hexapeptide repeat containing protein	-	-	2.7.7.13,5.4.2.8	ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II,PGM_PMM_III
CMS1_k127_2391816_6	660470.Theba_2253	3.823e-35	149.0	28N4R@1|root,2ZBA5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4015
CMS1_k127_2391816_0	1089550.ATTH01000001_gene1655	1.823e-167	535.0	COG5441@1|root,COG5441@2|Bacteria,4NHS7@976|Bacteroidetes	976|Bacteroidetes	S	Uncharacterised protein family (UPF0261)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0261
CMS1_k127_2391816_1	891968.Anamo_0105	3.935e-139	447.0	COG5564@1|root,COG5564@2|Bacteria,3TAR9@508458|Synergistetes	508458|Synergistetes	S	TIM-barrel signal transduction protein	-	-	-	-	-	-	-	-	-	-	-	-	PEP_hydrolase
CMS1_k127_2391816_4	1205680.CAKO01000037_gene1216	1.371e-82	282.0	COG3836@1|root,COG3836@2|Bacteria	2|Bacteria	G	2-keto-3-deoxy-L-rhamnonate aldolase activity	mphE	-	4.1.2.52,4.1.2.53	ko:K02510,ko:K12660	ko00051,ko00350,ko01120,map00051,map00350,map01120	-	R01645,R01647,R02261	RC00307,RC00435,RC00572,RC00574,RC03057	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
CMS1_k127_2391816_2	266117.Rxyl_0283	7.441e-105	347.0	COG2343@1|root,COG2343@2|Bacteria,2IKUM@201174|Actinobacteria,4CQ3S@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF427)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
CMS1_k127_2391816_3	926550.CLDAP_13670	5.71e-98	329.0	COG1070@1|root,COG1070@2|Bacteria,2G7KS@200795|Chloroflexi	200795|Chloroflexi	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
CMS1_k127_239787_1	926569.ANT_22780	7.589e-38	147.0	COG1047@1|root,COG1047@2|Bacteria,2G744@200795|Chloroflexi	200795|Chloroflexi	G	FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K01802,ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
CMS1_k127_239787_0	926569.ANT_17680	2.343e-79	274.0	COG2047@1|root,COG2047@2|Bacteria	2|Bacteria	S	protein (ATP-grasp superfamily)	-	-	-	ko:K07159	-	-	-	-	ko00000	-	-	-	PAC2
CMS1_k127_239787_2	765420.OSCT_1006	7.903e-13	74.0	COG5427@1|root,COG5427@2|Bacteria,2G6AA@200795|Chloroflexi,37682@32061|Chloroflexia	32061|Chloroflexia	S	Uncharacterized membrane protein (DUF2298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2298
CMS1_k127_2423651_18	696281.Desru_2469	7.101e-19	92.0	COG0566@1|root,COG0566@2|Bacteria,1V3JP@1239|Firmicutes,248DV@186801|Clostridia,261RV@186807|Peptococcaceae	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	spoU	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
CMS1_k127_2423651_6	926569.ANT_16950	1.451e-118	393.0	COG0436@1|root,COG0436@2|Bacteria,2G60K@200795|Chloroflexi	200795|Chloroflexi	E	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate	dapL	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS1_k127_2423651_9	926569.ANT_15670	1.106e-64	237.0	COG0642@1|root,COG2205@2|Bacteria	926569.ANT_15670|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2423651_2	926550.CLDAP_10840	6.713e-179	570.0	COG1206@1|root,COG1206@2|Bacteria,2GBNY@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	-	-	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
CMS1_k127_2423651_7	1521187.JPIM01000103_gene1041	1.72e-115	386.0	COG0303@1|root,COG0303@2|Bacteria,2G6AK@200795|Chloroflexi,375EW@32061|Chloroflexia	32061|Chloroflexia	H	MoeA domain protein domain I and II	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
CMS1_k127_2423651_14	443143.GM18_4465	1.032e-24	107.0	COG2005@1|root,COG2005@2|Bacteria,1MZ31@1224|Proteobacteria,42NA0@68525|delta/epsilon subdivisions,2WRTB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	ko:K02019	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1
CMS1_k127_2423651_8	1128421.JAGA01000002_gene1253	2.432e-110	371.0	COG0464@1|root,COG0464@2|Bacteria	2|Bacteria	O	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA
CMS1_k127_2423651_4	1128421.JAGA01000002_gene1253	6.82e-155	500.0	COG0464@1|root,COG0464@2|Bacteria	2|Bacteria	O	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA
CMS1_k127_2423651_17	573064.Mefer_0647	7.996e-20	94.0	COG0745@1|root,arCOG02595@2157|Archaea,2XZE9@28890|Euryarchaeota,23R5U@183939|Methanococci	183939|Methanococci	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS1_k127_2423651_3	887898.HMPREF0551_1628	1.601e-162	523.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,2VI2T@28216|Betaproteobacteria,1K1FI@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ASL_C,Lyase_1
CMS1_k127_2423651_5	926550.CLDAP_19630	1.644e-154	499.0	COG2262@1|root,COG2262@2|Bacteria,2G634@200795|Chloroflexi	200795|Chloroflexi	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
CMS1_k127_2423651_13	1305737.JAFX01000001_gene803	4.275e-25	108.0	COG0023@1|root,COG0023@2|Bacteria,4NS6M@976|Bacteroidetes,47R38@768503|Cytophagia	976|Bacteroidetes	J	PFAM translation initiation factor SUI1	-	-	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
CMS1_k127_2423651_16	926550.CLDAP_35190	9.495e-21	96.0	2FKJC@1|root,34C6D@2|Bacteria,2G9T3@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2423651_10	1499967.BAYZ01000147_gene726	3.344e-59	225.0	COG0664@1|root,COG1752@1|root,COG3437@1|root,COG0664@2|Bacteria,COG1752@2|Bacteria,COG3437@2|Bacteria	2|Bacteria	T	response regulator, receiver	-	-	3.1.3.3	ko:K07001,ko:K07315,ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03021	-	-	-	HTH_Crp_2,Patatin,Response_reg,SpoIIE,cNMP_binding
CMS1_k127_2423651_11	326427.Cagg_1302	1.927e-51	192.0	COG0300@1|root,COG0300@2|Bacteria,2G8KG@200795|Chloroflexi,376QV@32061|Chloroflexia	32061|Chloroflexia	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS1_k127_2423651_19	604331.AUHY01000056_gene1308	8.059e-09	60.0	2EC2Y@1|root,3361X@2|Bacteria,1WKKQ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	TIGRFAM Lysine biosynthesis protein LysW	lysW	-	-	ko:K05826	-	M00031,M00763	-	-	ko00000,ko00001,ko00002	-	-	-	TF_Zn_Ribbon
CMS1_k127_2423651_20	604331.AUHY01000056_gene1308	7.661e-08	55.0	2EC2Y@1|root,3361X@2|Bacteria,1WKKQ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	TIGRFAM Lysine biosynthesis protein LysW	lysW	-	-	ko:K05826	-	M00031,M00763	-	-	ko00000,ko00001,ko00002	-	-	-	TF_Zn_Ribbon
CMS1_k127_2423651_15	926550.CLDAP_39990	5.414e-21	96.0	COG1734@1|root,COG1734@2|Bacteria	2|Bacteria	T	zinc ion binding	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
CMS1_k127_2423651_12	1382306.JNIM01000001_gene325	3.278e-33	137.0	COG0745@1|root,COG0745@2|Bacteria	1382306.JNIM01000001_gene325|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2423651_1	926550.CLDAP_30360	1.225e-188	635.0	COG3391@1|root,COG5305@1|root,COG3391@2|Bacteria,COG5305@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS1_k127_2423651_0	926550.CLDAP_30370	1.006e-196	651.0	COG3391@1|root,COG4745@1|root,COG3391@2|Bacteria,COG4745@2|Bacteria,2G5PE@200795|Chloroflexi	200795|Chloroflexi	O	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NHL,PMT_2
CMS1_k127_242686_12	102125.Xen7305DRAFT_00004430	2.666e-09	59.0	COG1523@1|root,COG1523@2|Bacteria,1G0PW@1117|Cyanobacteria,3VIKJ@52604|Pleurocapsales	1117|Cyanobacteria	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
CMS1_k127_242686_1	765910.MARPU_02035	2.338e-151	497.0	COG1283@1|root,COG1283@2|Bacteria,1MUDE@1224|Proteobacteria,1RNMM@1236|Gammaproteobacteria,1WXUR@135613|Chromatiales	135613|Chromatiales	P	PFAM Na Picotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
CMS1_k127_242686_6	269797.Mbar_A2402	7.505e-40	157.0	arCOG03338@1|root,arCOG03338@2157|Archaea,2XXKV@28890|Euryarchaeota,2NA0P@224756|Methanomicrobia	224756|Methanomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_242686_5	1499967.BAYZ01000159_gene545	9.409e-68	241.0	COG3568@1|root,COG3568@2|Bacteria	2|Bacteria	N	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CBM_4_9,Exo_endo_phos,F5_F8_type_C,FIVAR,Laminin_G_3,Lyase_8,Lyase_8_C,Lyase_8_N
CMS1_k127_242686_9	1125863.JAFN01000001_gene1998	5.491e-25	108.0	COG1708@1|root,COG1708@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	ant1	-	2.7.7.47	ko:K00984,ko:K19279	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	DUF4111,NTP_transf_2,UPF0158
CMS1_k127_242686_2	338963.Pcar_1390	2.897e-147	477.0	COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,42MBN@68525|delta/epsilon subdivisions,2WINT@28221|Deltaproteobacteria,43T6E@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
CMS1_k127_242686_13	670487.Ocepr_0856	1.444e-08	68.0	COG1652@1|root,COG1652@2|Bacteria	2|Bacteria	S	positive regulation of growth rate	-	-	-	-	-	-	-	-	-	-	-	-	LysM
CMS1_k127_242686_4	1333998.M2A_0834	7.687e-84	301.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS1_k127_242686_3	479434.Sthe_1079	5.571e-131	437.0	COG0661@1|root,COG0661@2|Bacteria,2G6DN@200795|Chloroflexi,27XIC@189775|Thermomicrobia	189775|Thermomicrobia	S	ABC1 family	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
CMS1_k127_242686_7	378806.STAUR_5419	5.252e-36	152.0	COG1562@1|root,COG1562@2|Bacteria,1R4ZD@1224|Proteobacteria	1224|Proteobacteria	I	PFAM Squalene phytoene synthase	fdfT	-	2.5.1.21	ko:K00801	ko00100,ko00909,ko01100,ko01110,ko01130,map00100,map00909,map01100,map01110,map01130	-	R00702,R02872,R06223	RC00362,RC00796,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	SQS_PSY
CMS1_k127_242686_11	552811.Dehly_0105	1.656e-15	89.0	COG1714@1|root,COG1714@2|Bacteria,2GAT1@200795|Chloroflexi,34DA7@301297|Dehalococcoidia	301297|Dehalococcoidia	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
CMS1_k127_242686_0	386456.JQKN01000004_gene217	2.756e-211	677.0	COG1950@1|root,arCOG09731@2157|Archaea,2Y2F9@28890|Euryarchaeota,23PAN@183925|Methanobacteria	183925|Methanobacteria	S	Mycobacterial 4 TMS phage holin, superfamily IV	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2,Phosphodiest
CMS1_k127_242686_10	1229172.JQFA01000004_gene1804	5.309e-18	89.0	COG1357@1|root,COG1357@2|Bacteria,1G66I@1117|Cyanobacteria,1HB7P@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
CMS1_k127_242686_8	1267535.KB906767_gene1663	2.001e-34	151.0	COG4257@1|root,COG4257@2|Bacteria	2|Bacteria	V	antibiotic catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF5011,SLH
CMS1_k127_2438344_0	416591.Tlet_1422	6.35e-129	421.0	COG2309@1|root,COG2309@2|Bacteria,2GC5H@200918|Thermotogae	200918|Thermotogae	E	PFAM peptidase M29, aminopeptidase II	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
CMS1_k127_2438344_1	485913.Krac_11077	1.178e-127	417.0	COG2008@1|root,COG2008@2|Bacteria,2G7UV@200795|Chloroflexi	200795|Chloroflexi	E	Beta-eliminating lyase	-	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
CMS1_k127_2438344_2	2325.TKV_c05950	5.063e-35	156.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,42FJK@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	oppB	-	-	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
CMS1_k127_2440115_0	1121939.L861_17050	1.754e-128	415.0	COG1850@1|root,COG1850@2|Bacteria,1MWEB@1224|Proteobacteria,1RZ4S@1236|Gammaproteobacteria,1XNMS@135619|Oceanospirillales	135619|Oceanospirillales	G	Belongs to the RuBisCO large chain family	-	-	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
CMS1_k127_2440115_1	1122917.KB899667_gene3588	7.534e-128	423.0	COG3395@1|root,COG3395@2|Bacteria,1W75C@1239|Firmicutes,4HUD8@91061|Bacilli,26R32@186822|Paenibacillaceae	91061|Bacilli	S	Putative nucleotide-binding of sugar-metabolising enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DUF1357_C,DUF1537
CMS1_k127_2440115_3	485913.Krac_0432	2.665e-39	158.0	COG3173@1|root,COG3173@2|Bacteria,2G9DT@200795|Chloroflexi	200795|Chloroflexi	S	PFAM aminoglycoside phosphotransferase	-	-	2.7.1.163	ko:K18817	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	APH
CMS1_k127_2440115_2	397291.C804_06258	4.737e-73	252.0	COG1321@1|root,COG1321@2|Bacteria,1UZX6@1239|Firmicutes,248DA@186801|Clostridia,27QY7@186928|unclassified Lachnospiraceae	186801|Clostridia	K	iron dependent repressor	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_246070_2	1254432.SCE1572_23415	1.27e-43	166.0	COG1028@1|root,COG1028@2|Bacteria,1MWB6@1224|Proteobacteria,42S4A@68525|delta/epsilon subdivisions,2WNE7@28221|Deltaproteobacteria,2Z3AJ@29|Myxococcales	28221|Deltaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.127	ko:K00065	ko00040,map00040	-	R01542	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short,adh_short_C2
CMS1_k127_246070_1	1395587.P364_0107725	3.099e-47	180.0	COG1028@1|root,COG1028@2|Bacteria,1TSCT@1239|Firmicutes,4HD4Z@91061|Bacilli,26S0W@186822|Paenibacillaceae	91061|Bacilli	IQ	short-chain dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS1_k127_246070_0	1121937.AUHJ01000009_gene1566	4.587e-64	222.0	COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,1S3PD@1236|Gammaproteobacteria,468KZ@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015075,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
CMS1_k127_246070_3	1122176.KB903531_gene3073	3.475e-39	165.0	COG2312@1|root,COG2312@2|Bacteria,4PP0J@976|Bacteroidetes	976|Bacteroidetes	E	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,LTD
CMS1_k127_246070_4	485918.Cpin_1605	4.921e-10	60.0	2C4KB@1|root,32YM4@2|Bacteria,4NUZU@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2467256_3	102232.GLO73106DRAFT_00031350	1.036e-54	196.0	COG1848@1|root,COG1848@2|Bacteria,1G51H@1117|Cyanobacteria	1117|Cyanobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
CMS1_k127_2467256_5	1123400.KB904803_gene1671	5.062e-13	70.0	2BGN2@1|root,32AKR@2|Bacteria,1NJT2@1224|Proteobacteria,1SVAK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2467256_6	395961.Cyan7425_2965	3.815e-06	50.0	COG1476@1|root,COG1476@2|Bacteria,1G3Z7@1117|Cyanobacteria	1117|Cyanobacteria	K	Cro/C1-type HTH DNA-binding domain	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	Clp_N,HTH_3
CMS1_k127_2467256_1	926550.CLDAP_17040	2.163e-87	326.0	COG5276@1|root,COG5276@2|Bacteria,2G8F2@200795|Chloroflexi	200795|Chloroflexi	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
CMS1_k127_2467256_2	221288.JH992901_gene2459	5.83e-76	263.0	COG0454@1|root,COG0456@2|Bacteria,1GD5Y@1117|Cyanobacteria,1JHKK@1189|Stigonemataceae	1117|Cyanobacteria	K	GNAT acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,FR47
CMS1_k127_2467256_0	926560.KE387023_gene2040	2.965e-133	434.0	COG0624@1|root,COG0624@2|Bacteria,1WMBR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
CMS1_k127_2467256_4	395961.Cyan7425_0121	8.382e-23	102.0	COG3744@1|root,COG3744@2|Bacteria,1G9VS@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
CMS1_k127_2483856_3	1144312.PMI09_01878	2.283e-11	72.0	COG0457@1|root,COG0457@2|Bacteria,1MX2U@1224|Proteobacteria,2TVI2@28211|Alphaproteobacteria,4B7BJ@82115|Rhizobiaceae	28211|Alphaproteobacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,HEAT_2,Paired_CXXCH_1,TPR_14,TPR_16,TPR_19,TPR_2,TPR_8
CMS1_k127_2483856_0	926569.ANT_21940	2.969e-151	496.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114	-	ko:K15876	ko00910,ko01120,map00910,map01120	M00530	R05712	RC00176	ko00000,ko00001,ko00002	-	-	-	Cytochrom_NNT,Cytochrom_c3_2
CMS1_k127_2483856_2	671143.DAMO_0820	2.19e-23	106.0	COG0723@1|root,COG0723@2|Bacteria,2NQ46@2323|unclassified Bacteria	2|Bacteria	C	Rieske [2Fe-2S] domain	petA	-	1.10.2.2,1.10.9.1	ko:K00411,ko:K02636,ko:K03886	ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152,M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	iAF987.Gmet_1922	CytB6-F_Fe-S,Rieske,UCR_Fe-S_N
CMS1_k127_2483856_1	1379698.RBG1_1C00001G0780	7.89e-94	320.0	COG1290@1|root,COG1290@2|Bacteria,2NP8C@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome b(N-terminal)/b6/petB	petB	-	-	ko:K00410,ko:K00412,ko:K02635,ko:K02637	ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152,M00162	-	-	ko00000,ko00001,ko00002,ko00194,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_C1,Cytochrome_B
CMS1_k127_2483856_4	1250006.JHZZ01000001_gene2731	0.0006389	51.0	COG3043@1|root,COG3043@2|Bacteria,4NG82@976|Bacteroidetes,1HZDY@117743|Flavobacteriia	976|Bacteroidetes	C	anaerobic respiration	-	-	-	ko:K02568	ko00910,ko01120,map00910,map01120	M00529,M00530	R00798	RC02812	ko00000,ko00001,ko00002	-	-	-	Cytochrome_C554,NapB
CMS1_k127_24882_3	338963.Pcar_0628	4.838e-60	208.0	COG2513@1|root,COG2513@2|Bacteria,1N4VT@1224|Proteobacteria,42PWB@68525|delta/epsilon subdivisions,2X5K5@28221|Deltaproteobacteria,43VRB@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Phosphoenolpyruvate phosphomutase	-	-	5.4.2.9	ko:K01841	ko00440,ko01100,ko01120,ko01130,map00440,map01100,map01120,map01130	-	R00661	RC02792	ko00000,ko00001,ko01000	-	-	-	CTP_transf_like,NTP_transf_3,PEP_mutase
CMS1_k127_24882_0	338963.Pcar_0629	3.171e-113	374.0	COG1052@1|root,COG1052@2|Bacteria,1REXX@1224|Proteobacteria,42R07@68525|delta/epsilon subdivisions,2X7JR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.310,1.1.1.399,1.1.1.95	ko:K00058,ko:K16843	ko00260,ko00270,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513,R05693	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
CMS1_k127_24882_7	670292.JH26_16725	1.225e-35	149.0	COG0726@1|root,COG0726@2|Bacteria,1R7PS@1224|Proteobacteria,2TU1B@28211|Alphaproteobacteria,1JSKP@119045|Methylobacteriaceae	28211|Alphaproteobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,NodS,Polysacc_deac_1
CMS1_k127_24882_4	765913.ThidrDRAFT_4503	5.204e-60	226.0	COG0394@1|root,COG1073@1|root,COG3919@1|root,COG0394@2|Bacteria,COG1073@2|Bacteria,COG3919@2|Bacteria,1R61B@1224|Proteobacteria,1S0E7@1236|Gammaproteobacteria,1WYBD@135613|Chromatiales	135613|Chromatiales	T	TIGRFAM Hydrolase, ortholog 1, exosortase system type 1 associated	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Hydrolase_4
CMS1_k127_24882_9	1380390.JIAT01000010_gene4359	9.834e-16	86.0	COG0125@1|root,COG0125@2|Bacteria,2H78H@201174|Actinobacteria	201174|Actinobacteria	F	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_24882_6	1158050.KB895461_gene2929	5.333e-43	170.0	COG3173@1|root,COG3173@2|Bacteria,2H3VQ@201174|Actinobacteria	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS1_k127_24882_1	1185876.BN8_03655	9.141e-107	357.0	COG0675@1|root,COG0675@2|Bacteria,4NP20@976|Bacteroidetes,47PZD@768503|Cytophagia	976|Bacteroidetes	L	Probable transposase	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
CMS1_k127_24882_10	526225.Gobs_0360	7.97e-11	71.0	COG3173@1|root,COG3173@2|Bacteria,2H3VQ@201174|Actinobacteria	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS1_k127_24882_5	526225.Gobs_0361	3.008e-57	214.0	2C1GN@1|root,33V5B@2|Bacteria,2H4C5@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_24882_2	1128421.JAGA01000002_gene522	2.253e-81	275.0	COG2148@1|root,COG2148@2|Bacteria,2NPSP@2323|unclassified Bacteria	2|Bacteria	M	Bacterial sugar transferase	cpsE	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
CMS1_k127_24882_8	879212.DespoDRAFT_00252	1.51e-26	111.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,42V0K@68525|delta/epsilon subdivisions,2WR92@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM Cold-shock protein, DNA-binding	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
CMS1_k127_2488253_4	573065.Astex_1381	5.736e-09	60.0	COG1621@1|root,COG1621@2|Bacteria,1R103@1224|Proteobacteria	1224|Proteobacteria	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
CMS1_k127_2488253_2	908612.HMPREF9720_0068	8.285e-64	232.0	COG4409@1|root,COG4409@2|Bacteria,4NIWA@976|Bacteroidetes,2FVT0@200643|Bacteroidia	976|Bacteroidetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
CMS1_k127_2488253_3	1499967.BAYZ01000089_gene5019	1.387e-63	228.0	COG0329@1|root,COG0329@2|Bacteria,2NP5Q@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
CMS1_k127_2488253_0	1499967.BAYZ01000089_gene5014	3.767e-122	404.0	COG0043@1|root,COG0043@2|Bacteria	2|Bacteria	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity	ubiD	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
CMS1_k127_2488253_1	1304875.JAFZ01000001_gene1319	6.777e-75	264.0	COG1212@1|root,COG1212@2|Bacteria,3TA3G@508458|Synergistetes	508458|Synergistetes	H	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
CMS1_k127_2488253_5	67352.JODS01000019_gene2764	2.771e-08	59.0	COG1846@1|root,COG1846@2|Bacteria,2IHYF@201174|Actinobacteria	201174|Actinobacteria	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
CMS1_k127_248962_1	330214.NIDE1491	9.579e-49	179.0	COG0745@1|root,COG2202@1|root,COG3829@1|root,COG4585@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG3829@2|Bacteria,COG4585@2|Bacteria,COG5002@2|Bacteria,3J12P@40117|Nitrospirae	40117|Nitrospirae	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,HATPase_c,HisKA_3,PAS_9
CMS1_k127_248962_0	56780.SYN_01953	1.124e-78	267.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42R03@68525|delta/epsilon subdivisions,2WMTZ@28221|Deltaproteobacteria,2MRIP@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS1_k127_248962_2	1499967.BAYZ01000034_gene1071	4.313e-45	166.0	2E46N@1|root,32Z2M@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_248962_3	1047013.AQSP01000122_gene2227	5.474e-28	118.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K02282,ko:K07705	ko02020,map02020	M00492	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	GerE,Response_reg,TauD
CMS1_k127_248962_5	1235797.C816_03302	4.357e-08	61.0	COG1329@1|root,COG1329@2|Bacteria,1V40K@1239|Firmicutes,24HHP@186801|Clostridia,2N7DW@216572|Oscillospiraceae	186801|Clostridia	K	CarD-like/TRCF domain	carD	-	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
CMS1_k127_248962_4	338963.Pcar_0934	5.175e-22	111.0	COG0457@1|root,COG0457@2|Bacteria,1R4RP@1224|Proteobacteria,42NED@68525|delta/epsilon subdivisions,2WMDQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4037)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4037
CMS1_k127_2507186_6	485913.Krac_7645	9.713e-05	50.0	COG3307@1|root,COG3307@2|Bacteria,2G6TE@200795|Chloroflexi	200795|Chloroflexi	M	PFAM O-antigen polymerase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
CMS1_k127_2507186_1	926550.CLDAP_15490	1.152e-155	498.0	COG0451@1|root,COG0451@2|Bacteria,2G64F@200795|Chloroflexi	200795|Chloroflexi	M	PFAM NAD-dependent epimerase dehydratase	-	-	4.1.1.35,4.2.1.46	ko:K01710,ko:K08678	ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00793	R01384,R06513	RC00402,RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
CMS1_k127_2507186_4	383372.Rcas_3420	9.007e-39	163.0	COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,2GBIX@200795|Chloroflexi,3759D@32061|Chloroflexia	32061|Chloroflexia	T	SMART PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_4
CMS1_k127_2507186_5	370438.PTH_1831	4.213e-15	89.0	COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,25AZ2@186801|Clostridia,2605V@186807|Peptococcaceae	186801|Clostridia	K	PFAM response regulator receiver	phoB	-	-	ko:K02483,ko:K07658,ko:K07668	ko02020,map02020	M00434,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_2507186_3	926569.ANT_11680	1.531e-96	336.0	COG0823@1|root,COG3583@1|root,COG0823@2|Bacteria,COG3583@2|Bacteria	2|Bacteria	S	pathogenesis	-	-	-	ko:K21471,ko:K21687	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	GH23	-	G5,NLPC_P60,Peptidase_M26_C,YSIRK_signal
CMS1_k127_2507186_0	1191523.MROS_1932	2.985e-243	780.0	COG0249@1|root,COG0249@2|Bacteria	2|Bacteria	L	mismatched DNA binding	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
CMS1_k127_2507186_2	357808.RoseRS_0270	7.411e-119	407.0	COG0596@1|root,COG0596@2|Bacteria,2G6Y2@200795|Chloroflexi	200795|Chloroflexi	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
CMS1_k127_2510600_16	1499967.BAYZ01000104_gene3618	5.672e-41	152.0	COG0407@1|root,COG0407@2|Bacteria	2|Bacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
CMS1_k127_2510600_2	1121861.KB899913_gene2138	7.5e-189	605.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,2TR49@28211|Alphaproteobacteria,2JQX4@204441|Rhodospirillales	204441|Rhodospirillales	E	Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
CMS1_k127_2510600_15	1191523.MROS_2687	1.719e-41	154.0	COG2827@1|root,COG2827@2|Bacteria	2|Bacteria	L	Endonuclease containing a URI domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
CMS1_k127_2510600_3	383372.Rcas_0946	3.671e-188	597.0	COG0448@1|root,COG0448@2|Bacteria,2G66Q@200795|Chloroflexi,374V0@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
CMS1_k127_2510600_4	926550.CLDAP_15240	2.097e-153	495.0	COG0448@1|root,COG0448@2|Bacteria,2G7W8@200795|Chloroflexi	200795|Chloroflexi	H	PFAM transferase hexapeptide repeat containing protein	-	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
CMS1_k127_2510600_18	926550.CLDAP_39450	1.025e-12	70.0	2DFYG@1|root,2ZTRA@2|Bacteria,2G9KK@200795|Chloroflexi	200795|Chloroflexi	J	Ribosomal protein S21	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
CMS1_k127_2510600_0	926569.ANT_10860	0.0	1596.0	COG0086@1|root,COG0086@2|Bacteria,2G632@200795|Chloroflexi	200795|Chloroflexi	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
CMS1_k127_2510600_17	697281.Mahau_2477	2.52e-25	116.0	COG4974@1|root,COG4974@2|Bacteria,1V2D0@1239|Firmicutes,25C3U@186801|Clostridia,42GCT@68295|Thermoanaerobacterales	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
CMS1_k127_2510600_5	1128421.JAGA01000002_gene1722	6.506e-136	445.0	COG5542@1|root,COG5542@2|Bacteria	2|Bacteria	O	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Mannosyl_trans2,PMT_2
CMS1_k127_2510600_10	1128421.JAGA01000003_gene3562	3.141e-73	266.0	COG1287@1|root,COG1287@2|Bacteria,2NRXU@2323|unclassified Bacteria	2|Bacteria	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
CMS1_k127_2510600_7	479434.Sthe_0720	4.705e-118	389.0	COG1186@1|root,COG1186@2|Bacteria,2G5P6@200795|Chloroflexi,27XS7@189775|Thermomicrobia	189775|Thermomicrobia	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
CMS1_k127_2510600_8	1121423.JONT01000009_gene1451	7.416e-95	319.0	COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,247JD@186801|Clostridia,260N3@186807|Peptococcaceae	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
CMS1_k127_2510600_12	765420.OSCT_2451	3.922e-59	209.0	COG0315@1|root,COG0315@2|Bacteria,2G6PC@200795|Chloroflexi,375NJ@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
CMS1_k127_2510600_14	926569.ANT_22470	5.425e-53	196.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,2G6YQ@200795|Chloroflexi	200795|Chloroflexi	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	moaD	-	2.8.1.12	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
CMS1_k127_2510600_11	1128421.JAGA01000002_gene129	1.352e-66	234.0	COG0571@1|root,COG0571@2|Bacteria,2NPCJ@2323|unclassified Bacteria	2|Bacteria	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
CMS1_k127_2510600_1	926550.CLDAP_20060	1.756e-235	771.0	COG1196@1|root,COG1196@2|Bacteria,2G64A@200795|Chloroflexi	200795|Chloroflexi	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
CMS1_k127_2510600_9	1499967.BAYZ01000118_gene3286	6.151e-77	268.0	COG0083@1|root,COG0083@2|Bacteria,2NPH7@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate	thrB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.1.39	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iECSE_1348.ECSE_0003,iJN678.thrB,iLJ478.TM0545,iSB619.SA_RS06620	GHMP_kinases_C,GHMP_kinases_N
CMS1_k127_2510600_6	926550.CLDAP_09460	2.546e-124	408.0	COG0136@1|root,COG0136@2|Bacteria,2G5T9@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the aspartate-semialdehyde dehydrogenase family	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
CMS1_k127_252693_2	479434.Sthe_0598	2.841e-53	206.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2G699@200795|Chloroflexi	200795|Chloroflexi	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
CMS1_k127_252693_3	1120797.KB908260_gene4073	6.383e-15	88.0	COG0515@1|root,COG3903@1|root,COG0515@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,233DM@1762|Mycobacteriaceae	201174|Actinobacteria	K	involved in signal transduction (via phosphorylation) involved in transcriptional regulatory mechanism and in the regulation of secondary metabolites catalytic activity ATP a protein ADP a phosphoprotein	pknK_2	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	AAA_22,GerE,NB-ARC,Pkinase,TPR_12
CMS1_k127_252693_4	290400.Jann_3709	1.773e-12	76.0	2A53S@1|root,30TSD@2|Bacteria,1RGSW@1224|Proteobacteria,2U8G5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_252693_1	485913.Krac_9268	1.617e-55	204.0	COG1028@1|root,COG1028@2|Bacteria	485913.Krac_9268|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_252693_5	4558.Sb02g007760.1	2.384e-06	55.0	2CXSG@1|root,2S4MA@2759|Eukaryota,380WK@33090|Viridiplantae,3GQQF@35493|Streptophyta,3M1QR@4447|Liliopsida,3I4KR@38820|Poales	35493|Streptophyta	S	Dirigent proteins impart stereoselectivity on the phenoxy radical-coupling reaction, yielding optically active lignans from two molecules of coniferyl alcohol in the biosynthesis of lignans, flavonolignans, and alkaloids and thus plays a central role in plant secondary metabolism	-	-	-	-	-	-	-	-	-	-	-	-	Dirigent,Jacalin
CMS1_k127_252693_0	622637.KE124774_gene479	1.706e-100	340.0	COG1960@1|root,COG1960@2|Bacteria,1MXMQ@1224|Proteobacteria,2U0CV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	acyl-CoA dehydrogenase	-	-	1.14.13.235	ko:K22027	-	-	-	-	ko00000,ko01000	-	-	-	Acyl-CoA_dh_2,Acyl-CoA_dh_N
CMS1_k127_2534824_0	485913.Krac_3018	1.058e-141	463.0	COG1132@1|root,COG1132@2|Bacteria,2G86M@200795|Chloroflexi	2|Bacteria	P	COGs COG1132 ABC-type multidrug transport system ATPase and permease components	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS1_k127_2534824_3	1365176.N186_00115	1.854e-08	61.0	arCOG07304@1|root,arCOG07304@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2534824_1	1343740.M271_09250	8.018e-65	228.0	COG0500@1|root,COG2226@2|Bacteria,2GKPQ@201174|Actinobacteria	201174|Actinobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS1_k127_2534824_2	515635.Dtur_0274	4.376e-34	138.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25,Methyltransf_31
CMS1_k127_2544011_1	324602.Caur_2225	3.092e-80	276.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2G790@200795|Chloroflexi,3750C@32061|Chloroflexia	32061|Chloroflexia	T	SMART protein phosphatase 2C domain protein	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_2,GAF_3,SpoIIE
CMS1_k127_2544011_0	1174528.JH992898_gene733	7.15e-209	664.0	COG2146@1|root,COG2146@2|Bacteria,1G2KG@1117|Cyanobacteria,1JK9R@1189|Stigonemataceae	1117|Cyanobacteria	P	Rieske-like [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske,Rieske_2
CMS1_k127_2544011_2	1499967.BAYZ01000068_gene1965	6.382e-61	216.0	COG2206@1|root,COG2206@2|Bacteria	2|Bacteria	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	3.6.1.11,3.6.1.40	ko:K01524,ko:K06950	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,HD_5
CMS1_k127_2544011_3	292459.STH2408	4.269e-57	208.0	COG0537@1|root,COG0537@2|Bacteria,1V83D@1239|Firmicutes,24PYH@186801|Clostridia	186801|Clostridia	FG	Domain of unknown function (DUF4269)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4269
CMS1_k127_2544011_5	1151292.QEW_3183	2.253e-22	100.0	COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,25AZ2@186801|Clostridia,25QP7@186804|Peptostreptococcaceae	186801|Clostridia	K	response regulator	phoP	-	-	ko:K02483,ko:K07658,ko:K07668	ko02020,map02020	M00434,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_2544011_4	316274.Haur_4146	1.039e-38	147.0	COG0372@1|root,COG0372@2|Bacteria,2G7NR@200795|Chloroflexi,3776D@32061|Chloroflexia	32061|Chloroflexia	H	Citrate synthase, C-terminal domain	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
CMS1_k127_2551379_1	909663.KI867150_gene769	4.488e-60	231.0	COG0655@1|root,COG3255@1|root,COG0655@2|Bacteria,COG3255@2|Bacteria,1MYKZ@1224|Proteobacteria,42SN9@68525|delta/epsilon subdivisions,2WP58@28221|Deltaproteobacteria,2MRMQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	I	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red,SCP2
CMS1_k127_2551379_9	767817.Desgi_3791	7.139e-09	69.0	COG3255@1|root,COG3255@2|Bacteria	2|Bacteria	I	Sterol carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
CMS1_k127_2551379_8	357808.RoseRS_3405	1.345e-20	107.0	COG3255@1|root,COG3255@2|Bacteria,2G7E8@200795|Chloroflexi	200795|Chloroflexi	I	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
CMS1_k127_2551379_0	42256.RradSPS_0358	5.748e-248	796.0	COG2909@1|root,COG2909@2|Bacteria,2HENR@201174|Actinobacteria,4CPC9@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,AAA_22,GerE
CMS1_k127_2551379_7	329726.AM1_6084	5.69e-21	94.0	2DNVA@1|root,32ZBE@2|Bacteria,1GFXX@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2551379_3	1173020.Cha6605_2235	8.833e-37	144.0	2ESZ4@1|root,33KHC@2|Bacteria,1GDJQ@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2551379_2	671143.DAMO_1921	5.936e-57	214.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS1_k127_257251_1	649638.Trad_2350	2.498e-250	783.0	COG1132@1|root,COG1132@2|Bacteria	2|Bacteria	V	(ABC) transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS1_k127_257251_0	649638.Trad_2349	7.139e-263	822.0	COG1132@1|root,COG1132@2|Bacteria,1WIMR@1297|Deinococcus-Thermus	2|Bacteria	V	ABC-type multidrug transport system ATPase and permease	yknV	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS1_k127_257251_2	537970.HCAN_1114	6.51e-20	89.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,42MNJ@68525|delta/epsilon subdivisions,2YMDC@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
CMS1_k127_2585217_0	296591.Bpro_3358	3.186e-247	767.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2VIP3@28216|Betaproteobacteria,4AARI@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
CMS1_k127_2585217_1	158190.SpiGrapes_1178	3.298e-23	108.0	COG0115@1|root,COG0115@2|Bacteria	2|Bacteria	E	branched-chain-amino-acid transaminase activity	ilvE	GO:0003674,GO:0003824,GO:0004084,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006531,GO:0006532,GO:0006551,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009098,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.21,2.6.1.42	ko:K00824,ko:K00826	ko00270,ko00280,ko00290,ko00310,ko00330,ko00360,ko00472,ko00473,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00310,map00330,map00360,map00472,map00473,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01148,R01214,R01582,R02199,R02459,R02851,R02924,R05053,R10991	RC00006,RC00008,RC00025,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iB21_1397.B21_03597,iECBD_1354.ECBD_4269,iECB_1328.ECB_03648,iECD_1391.ECD_03648,iECO103_1326.ECO103_4394	Aminotran_4
CMS1_k127_2587345_1	525904.Tter_0620	1.087e-87	300.0	COG2006@1|root,COG2006@2|Bacteria	2|Bacteria	U	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088,DUF362
CMS1_k127_2587345_2	397948.Cmaq_0433	2.52e-42	167.0	COG1082@1|root,arCOG01900@2157|Archaea,2XRPH@28889|Crenarchaeota	28889|Crenarchaeota	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS1_k127_2587345_0	156889.Mmc1_2685	1.231e-99	368.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2TQVN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,DZR,Guanylate_cyc,TPR_12
CMS1_k127_2587345_3	1278073.MYSTI_05012	3.911e-17	98.0	COG0515@1|root,COG0515@2|Bacteria	1278073.MYSTI_05012|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2611127_1	1380386.JIAW01000038_gene1327	2.334e-70	259.0	COG3209@1|root,COG3209@2|Bacteria,2I60K@201174|Actinobacteria,2375A@1762|Mycobacteriaceae	201174|Actinobacteria	M	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,RCC1_2
CMS1_k127_2611127_0	160860.XP_007338670.1	1.277e-151	490.0	COG0165@1|root,KOG1316@2759|Eukaryota,38CSU@33154|Opisthokonta,3NVYH@4751|Fungi,3UZR9@5204|Basidiomycota,227TP@155619|Agaricomycetes,3H2VC@355688|Agaricomycetes incertae sedis	4751|Fungi	E	Argininosuccinate lyase	ARG4	GO:0000050,GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
CMS1_k127_2616631_2	221288.JH992901_gene2820	1.956e-23	100.0	COG1247@1|root,COG1247@2|Bacteria	2|Bacteria	M	phosphinothricin N-acetyltransferase activity	-	-	-	ko:K03825	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_4
CMS1_k127_2616631_3	492774.JQMB01000007_gene4005	6.067e-18	91.0	COG1514@1|root,COG1514@2|Bacteria	2|Bacteria	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2,LigT_PEase
CMS1_k127_2616631_4	1128421.JAGA01000004_gene2679	2.149e-17	93.0	COG5485@1|root,COG5485@2|Bacteria,2NRTW@2323|unclassified Bacteria	2|Bacteria	S	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
CMS1_k127_2616631_0	324602.Caur_3820	6.969e-56	215.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2G7SC@200795|Chloroflexi	200795|Chloroflexi	K	intracellular signal transduction	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12
CMS1_k127_2616631_5	1242864.D187_003855	8.888e-05	55.0	COG0515@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,43BX5@68525|delta/epsilon subdivisions,2X77Z@28221|Deltaproteobacteria,2YY1C@29|Myxococcales	28221|Deltaproteobacteria	KLT	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,GAF_2,HATPase_c,Pkinase
CMS1_k127_26214_2	365046.Rta_27510	1.297e-16	81.0	COG3382@1|root,COG3382@2|Bacteria,1NXK4@1224|Proteobacteria,2VR20@28216|Betaproteobacteria,4AE28@80864|Comamonadaceae	28216|Betaproteobacteria	S	B3/4 domain	-	-	-	-	-	-	-	-	-	-	-	-	B3_4
CMS1_k127_26214_3	1121382.JQKG01000015_gene1660	9.655e-14	78.0	2DP69@1|root,330Q1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_26214_4	118168.MC7420_8162	1.898e-12	68.0	COG1403@1|root,COG1403@2|Bacteria,1G6DP@1117|Cyanobacteria,1HBF4@1150|Oscillatoriales	1117|Cyanobacteria	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH,HNH_5
CMS1_k127_26214_1	1173027.Mic7113_4898	1e-35	138.0	2B350@1|root,31VSS@2|Bacteria,1G7IM@1117|Cyanobacteria,1HDSR@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_26214_0	357808.RoseRS_2190	2.678e-292	923.0	COG2373@1|root,COG2373@2|Bacteria,2G5XN@200795|Chloroflexi	200795|Chloroflexi	S	PFAM alpha-2-macroglobulin domain protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,Big_5,MG1
CMS1_k127_263004_5	592015.HMPREF1705_01539	6.405e-41	154.0	COG0693@1|root,COG0693@2|Bacteria,3TB17@508458|Synergistetes	508458|Synergistetes	S	TIGRFAM intracellular protease, PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
CMS1_k127_263004_6	1385511.N783_04050	9.187e-35	138.0	COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,4HIJ0@91061|Bacilli,2YA90@289201|Pontibacillus	91061|Bacilli	C	Nitrogen-fixing protein NifU	nifU	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0097428,GO:0098771,GO:1901564	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
CMS1_k127_263004_7	638303.Thal_1022	7.547e-10	72.0	COG0785@1|root,COG0785@2|Bacteria,2G4XU@200783|Aquificae	200783|Aquificae	O	PFAM Cytochrome C biogenesis protein transmembrane region	ccdA	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
CMS1_k127_263004_10	460265.Mnod_3274	0.0001428	50.0	COG2010@1|root,COG2133@1|root,COG2010@2|Bacteria,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,2TRN9@28211|Alphaproteobacteria,1JTMF@119045|Methylobacteriaceae	28211|Alphaproteobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,GSDH
CMS1_k127_263004_11	446466.Cfla_3533	0.0009692	51.0	COG3391@1|root,COG3391@2|Bacteria,2GK45@201174|Actinobacteria	201174|Actinobacteria	M	40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1,Lactonase
CMS1_k127_263004_2	1382356.JQMP01000004_gene592	3.175e-68	239.0	COG2197@1|root,COG2197@2|Bacteria,2G8EU@200795|Chloroflexi,27XKP@189775|Thermomicrobia	189775|Thermomicrobia	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS1_k127_263004_3	479434.Sthe_0156	2.38e-59	227.0	COG3850@1|root,COG3850@2|Bacteria,2GBH4@200795|Chloroflexi,27XF0@189775|Thermomicrobia	189775|Thermomicrobia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
CMS1_k127_263004_4	926569.ANT_26550	5.43e-47	179.0	COG3212@1|root,COG3212@2|Bacteria	2|Bacteria	T	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	PepSY
CMS1_k127_263004_1	42256.RradSPS_1351	8.475e-69	241.0	COG0745@1|root,COG0745@2|Bacteria,2GJE6@201174|Actinobacteria,4CPX6@84995|Rubrobacteria	84995|Rubrobacteria	K	COG COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms Transcription	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_263004_0	357808.RoseRS_3736	6.317e-87	306.0	COG0642@1|root,COG5000@1|root,COG2205@2|Bacteria,COG5000@2|Bacteria,2GBIC@200795|Chloroflexi,3780I@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
CMS1_k127_263004_9	880072.Desac_0072	5.258e-07	52.0	COG0394@1|root,COG0394@2|Bacteria,1MWYQ@1224|Proteobacteria,42SQK@68525|delta/epsilon subdivisions,2WPK1@28221|Deltaproteobacteria,2MS9M@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Low molecular weight phosphatase family	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
CMS1_k127_2640537_21	525904.Tter_2138	2.315e-17	82.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_2640537_7	525904.Tter_2135	4.74e-94	318.0	COG0395@1|root,COG0395@2|Bacteria	525904.Tter_2135|-	P	glycerophosphodiester transmembrane transport	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	-
CMS1_k127_2640537_5	525904.Tter_2136	9.931e-106	353.0	COG1175@1|root,COG1175@2|Bacteria	2|Bacteria	P	transmembrane transport	-	-	-	ko:K02025,ko:K05814,ko:K10118,ko:K10237,ko:K10241,ko:K15771,ko:K17235,ko:K17316	ko02010,map02010	M00196,M00198,M00204,M00206,M00207,M00491,M00602,M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.17,3.A.1.1.2,3.A.1.1.23,3.A.1.1.24,3.A.1.1.28,3.A.1.1.3,3.A.1.1.30,3.A.1.1.34	-	-	BPD_transp_1
CMS1_k127_2640537_8	525904.Tter_2137	4.461e-93	323.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
CMS1_k127_2640537_19	330214.NIDE1784	1.016e-27	123.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_11,Methyltransf_23
CMS1_k127_2640537_12	913865.DOT_4724	2.851e-74	269.0	COG5598@1|root,COG5598@2|Bacteria,1TR30@1239|Firmicutes,24CK1@186801|Clostridia,25ZYG@186807|Peptococcaceae	186801|Clostridia	H	PFAM Trimethylamine methyltransferase (MTTB)	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
CMS1_k127_2640537_10	525904.Tter_2139	3.885e-80	277.0	COG1940@1|root,COG1940@2|Bacteria	2|Bacteria	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
CMS1_k127_2640537_4	1410620.SHLA_13c000490	2.028e-110	364.0	COG0662@1|root,COG1917@1|root,COG0662@2|Bacteria,COG1917@2|Bacteria,1Q84M@1224|Proteobacteria,2VEAD@28211|Alphaproteobacteria,4BEAB@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS1_k127_2640537_0	525904.Tter_2141	1.683e-153	492.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_2640537_1	357808.RoseRS_4474	1.506e-151	492.0	COG0613@1|root,COG0613@2|Bacteria	2|Bacteria	Q	PHP domain protein	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP_C
CMS1_k127_2640537_11	525904.Tter_2142	5.51e-79	271.0	COG2188@1|root,COG2188@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
CMS1_k127_2640537_13	357808.RoseRS_3344	9.773e-69	241.0	COG0846@1|root,COG0846@2|Bacteria,2G6QQ@200795|Chloroflexi,375GJ@32061|Chloroflexia	32061|Chloroflexia	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	-	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
CMS1_k127_2640537_15	1172188.KB911821_gene2078	2.11e-50	194.0	COG0642@1|root,COG2205@2|Bacteria,2I2M2@201174|Actinobacteria,4FFYD@85021|Intrasporangiaceae	201174|Actinobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,GAF_2,HAMP,HATPase_c,HisKA,Response_reg
CMS1_k127_2640537_2	326427.Cagg_0598	6.652e-124	404.0	COG1063@1|root,COG1063@2|Bacteria,2G5WZ@200795|Chloroflexi,376KB@32061|Chloroflexia	32061|Chloroflexia	E	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_2640537_3	138119.DSY2459	4.035e-122	422.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,1TQVT@1239|Firmicutes,247X8@186801|Clostridia,260H2@186807|Peptococcaceae	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
CMS1_k127_2640537_16	1041146.ATZB01000005_gene6245	1.392e-39	154.0	COG2514@1|root,COG2514@2|Bacteria	2|Bacteria	S	catechol 2,3-dioxygenase activity	-	-	1.13.11.2	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
CMS1_k127_2640537_14	1289387.AUKW01000025_gene2866	1.679e-66	243.0	COG0654@1|root,COG0654@2|Bacteria,2GNA8@201174|Actinobacteria	201174|Actinobacteria	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	-	-	1.14.13.10	ko:K19189	ko00760,ko01120,map00760,map01120	-	R04130	RC00046	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3,NAD_binding_8
CMS1_k127_2640537_9	1123276.KB893246_gene700	3.144e-91	309.0	COG0657@1|root,COG0657@2|Bacteria,4PKKH@976|Bacteroidetes,47KC9@768503|Cytophagia	976|Bacteroidetes	I	alpha/beta hydrolase fold	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Abhydrolase_3,DLH
CMS1_k127_2640537_6	1366050.N234_37045	1.366e-101	370.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2VKH1@28216|Betaproteobacteria,1JZT2@119060|Burkholderiaceae	28216|Betaproteobacteria	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
CMS1_k127_2640537_18	1040983.AXAE01000012_gene2230	3.314e-38	167.0	COG2267@1|root,COG3629@1|root,COG2267@2|Bacteria,COG3629@2|Bacteria,1NIJG@1224|Proteobacteria,2U09P@28211|Alphaproteobacteria,43PM5@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	IT	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,BTAD,Hydrolase_4,Trans_reg_C
CMS1_k127_2640537_17	1041146.ATZB01000005_gene6245	1.858e-38	149.0	COG2514@1|root,COG2514@2|Bacteria	2|Bacteria	S	catechol 2,3-dioxygenase activity	-	-	1.13.11.2	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
CMS1_k127_2640537_20	1231391.AMZF01000020_gene2008	1.047e-26	115.0	COG0683@1|root,COG0683@2|Bacteria,1NHBN@1224|Proteobacteria	1224|Proteobacteria	E	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
CMS1_k127_2653528_2	926550.CLDAP_19610	1.32e-51	194.0	COG0589@1|root,COG0589@2|Bacteria,2GBJZ@200795|Chloroflexi	200795|Chloroflexi	T	response to stress	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS1_k127_2653528_0	1122917.KB899669_gene4670	3.259e-57	208.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,4HAA6@91061|Bacilli,274R0@186822|Paenibacillaceae	91061|Bacilli	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS1_k127_2653528_1	1079460.ATTQ01000017_gene4082	1.247e-51	190.0	COG3342@1|root,COG3342@2|Bacteria,1MWQT@1224|Proteobacteria,2TRJZ@28211|Alphaproteobacteria,4B6ZR@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Family of unknown function (DUF1028)	MA20_16755	-	-	-	-	-	-	-	-	-	-	-	DUF1028
CMS1_k127_2653528_3	546414.Deide_03660	1.115e-45	177.0	COG5640@1|root,COG5640@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin
CMS1_k127_2658381_2	1123242.JH636434_gene3396	5.817e-75	259.0	COG4221@1|root,COG4221@2|Bacteria,2IYGT@203682|Planctomycetes	203682|Planctomycetes	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS1_k127_2658381_3	1267535.KB906767_gene1679	1.898e-05	56.0	COG1649@1|root,COG1649@2|Bacteria	2|Bacteria	F	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	GHL10,GHL6,Glyco_hydro_42M,Polysacc_deac_1
CMS1_k127_2658381_1	926550.CLDAP_01900	3.388e-78	272.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	yvnB	-	3.1.4.53	ko:K03651	ko00230,ko02025,map00230,map02025	-	R00191	RC00296	ko00000,ko00001,ko01000	-	-	-	LTD,Laminin_G_3,Metallophos
CMS1_k127_2658381_0	485913.Krac_0910	1.035e-112	376.0	COG2936@1|root,COG2936@2|Bacteria	2|Bacteria	V	dipeptidyl-peptidase activity	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
CMS1_k127_2659917_2	28564.XP_002488590.1	3.474e-48	179.0	KOG0266@1|root,KOG0271@1|root,KOG0266@2759|Eukaryota,KOG0271@2759|Eukaryota,38B6D@33154|Opisthokonta,3NZ4C@4751|Fungi	4751|Fungi	D	WD40 repeat-like protein	-	-	-	-	-	-	-	-	-	-	-	-	NACHT,PNP_UDP_1,WD40
CMS1_k127_2659917_1	1487953.JMKF01000020_gene2252	2.012e-123	403.0	COG3173@1|root,COG3173@2|Bacteria	2|Bacteria	S	very-long-chain-acyl-CoA dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS1_k127_2659917_0	383372.Rcas_1705	1.139e-136	439.0	COG0667@1|root,COG0667@2|Bacteria,2G5N6@200795|Chloroflexi	200795|Chloroflexi	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS1_k127_2668330_5	886293.Sinac_6105	5.032e-48	179.0	COG4221@1|root,COG4221@2|Bacteria,2IYVR@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS1_k127_2668330_4	867903.ThesuDRAFT_02055	5.906e-54	191.0	COG0537@1|root,COG0537@2|Bacteria,1VB6J@1239|Firmicutes,24UA3@186801|Clostridia	186801|Clostridia	FG	HIT family hydrolase, diadenosine tetraphosphate hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HIT
CMS1_k127_2668330_2	1303518.CCALI_01967	2.464e-114	383.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	-	-	4.2.1.6	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R03033	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4433,MR_MLE_C
CMS1_k127_2668330_6	5932.XP_004040085.1	3.233e-12	75.0	2CY22@1|root,2S1E9@2759|Eukaryota	2759|Eukaryota	O	Taurine catabolism dioxygenase TauD, TfdA family	-	-	-	-	-	-	-	-	-	-	-	-	TauD
CMS1_k127_2668330_0	1156919.QWC_00370	5.139e-139	447.0	COG0388@1|root,COG3616@1|root,COG0388@2|Bacteria,COG3616@2|Bacteria,1MVQE@1224|Proteobacteria,2VJ3G@28216|Betaproteobacteria,3T3PK@506|Alcaligenaceae	28216|Betaproteobacteria	E	Putative serine dehydratase domain	-	-	4.3.1.18	ko:K01753	ko00260,map00260	-	R00221	RC02600	ko00000,ko00001,ko01000	-	-	-	Ala_racemase_N,D-ser_dehydrat
CMS1_k127_2668330_3	1382356.JQMP01000003_gene1376	1.328e-87	301.0	COG1363@1|root,COG1363@2|Bacteria,2GB54@200795|Chloroflexi,27YYZ@189775|Thermomicrobia	189775|Thermomicrobia	E	M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
CMS1_k127_2668330_1	1380356.JNIK01000018_gene862	4.553e-127	416.0	COG1062@1|root,COG1062@2|Bacteria,2GM8C@201174|Actinobacteria,4ERG3@85013|Frankiales	201174|Actinobacteria	C	PFAM Alcohol dehydrogenase zinc-binding domain protein	adhC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.1.1.306	ko:K00153	-	-	R09129,R10301	RC00069,RC01715	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_2680942_6	1382306.JNIM01000001_gene3678	1.199e-30	123.0	COG0501@1|root,COG0501@2|Bacteria,2G6KE@200795|Chloroflexi	200795|Chloroflexi	O	PFAM peptidase M48 Ste24p	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
CMS1_k127_2680942_2	1170562.Cal6303_4129	3.448e-48	177.0	COG2402@1|root,COG2402@2|Bacteria,1G5YI@1117|Cyanobacteria,1HSNX@1161|Nostocales	1117|Cyanobacteria	S	COGs COG2402 nucleic acid-binding protein contains PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
CMS1_k127_2680942_3	1382306.JNIM01000001_gene3678	4.134e-47	175.0	COG0501@1|root,COG0501@2|Bacteria,2G6KE@200795|Chloroflexi	200795|Chloroflexi	O	PFAM peptidase M48 Ste24p	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
CMS1_k127_2680942_5	869210.Marky_1921	4.15e-34	135.0	COG0517@1|root,COG5485@1|root,COG0517@2|Bacteria,COG5485@2|Bacteria,1WK3F@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
CMS1_k127_2680942_7	351160.RRC198	2.337e-25	111.0	COG5485@1|root,arCOG06513@2157|Archaea,2XYRZ@28890|Euryarchaeota,2NBCI@224756|Methanomicrobia	224756|Methanomicrobia	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
CMS1_k127_2680942_9	316274.Haur_5252	5.622e-05	48.0	COG2801@1|root,COG2801@2|Bacteria,2G8JR@200795|Chloroflexi	200795|Chloroflexi	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	rve
CMS1_k127_2680942_4	1111479.AXAR01000001_gene325	3.841e-35	148.0	COG0673@1|root,COG0673@2|Bacteria,1TQ72@1239|Firmicutes,4HAGN@91061|Bacilli,279IX@186823|Alicyclobacillaceae	91061|Bacilli	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_2680942_0	383372.Rcas_3701	2.335e-119	423.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GAAG@200795|Chloroflexi,374S4@32061|Chloroflexia	32061|Chloroflexia	K	transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,TPR_12,Trans_reg_C
CMS1_k127_2680942_1	1382306.JNIM01000001_gene3678	4.274e-68	236.0	COG0501@1|root,COG0501@2|Bacteria,2G6KE@200795|Chloroflexi	200795|Chloroflexi	O	PFAM peptidase M48 Ste24p	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
CMS1_k127_2689714_0	555088.DealDRAFT_1324	1.831e-87	295.0	COG1131@1|root,COG1131@2|Bacteria,1TQN1@1239|Firmicutes,25AZK@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_2689714_1	1297742.A176_01465	6.262e-55	222.0	COG2755@1|root,COG5640@1|root,COG2755@2|Bacteria,COG5640@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Calx-beta,Lipase_GDSL_2,Trypsin
CMS1_k127_2689714_2	309801.trd_1922	1.737e-31	145.0	COG0028@1|root,COG3055@1|root,COG0028@2|Bacteria,COG3055@2|Bacteria,2GBSZ@200795|Chloroflexi,27ZA5@189775|Thermomicrobia	189775|Thermomicrobia	EH	Belongs to the TPP enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2689714_3	1237149.C900_05009	0.0009866	50.0	COG0745@1|root,COG5002@1|root,COG0745@2|Bacteria,COG5002@2|Bacteria,4P0IA@976|Bacteroidetes,47YRP@768503|Cytophagia	976|Bacteroidetes	T	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HTH_18,HisKA,Response_reg,TPR_10,TPR_12,TPR_7,TPR_8
CMS1_k127_2693001_4	1521187.JPIM01000112_gene2337	7.685e-14	77.0	COG5305@1|root,COG5305@2|Bacteria,2G7AA@200795|Chloroflexi,375E4@32061|Chloroflexia	32061|Chloroflexia	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT_2
CMS1_k127_2693001_2	304371.MCP_2712	9.037e-27	127.0	arCOG00567@1|root,arCOG00567@2157|Archaea,2XVU1@28890|Euryarchaeota,2NA3X@224756|Methanomicrobia	224756|Methanomicrobia	M	glycosyl transferase, family 39	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS1_k127_2693001_1	1227453.C444_12182	1.672e-44	174.0	COG0392@1|root,arCOG00899@2157|Archaea,2Y788@28890|Euryarchaeota,240HY@183963|Halobacteria	183963|Halobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
CMS1_k127_2693001_0	383372.Rcas_0760	7.119e-118	388.0	COG0463@1|root,COG0463@2|Bacteria,2G5X5@200795|Chloroflexi,377Y9@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS1_k127_2693001_3	357808.RoseRS_2507	4.601e-25	112.0	COG5305@1|root,COG5305@2|Bacteria,2G7AA@200795|Chloroflexi,375E4@32061|Chloroflexia	200795|Chloroflexi	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS1_k127_2697160_13	383372.Rcas_0446	1.603e-21	97.0	COG1192@1|root,COG1192@2|Bacteria,2G8YP@200795|Chloroflexi,374WY@32061|Chloroflexia	32061|Chloroflexia	D	PFAM Cobyrinic acid a,c-diamide synthase	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
CMS1_k127_2697160_5	1122238.AULR01000021_gene1132	5.567e-72	251.0	COG1192@1|root,COG1192@2|Bacteria,2GJX3@201174|Actinobacteria,4FKN6@85023|Microbacteriaceae	201174|Actinobacteria	D	Cellulose biosynthesis protein BcsQ	soj	GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
CMS1_k127_2697160_17	1449044.JMLE01000014_gene2294	1.039e-09	63.0	2EGYZ@1|root,33AR3@2|Bacteria,2IN24@201174|Actinobacteria,1WBV7@1268|Micrococcaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2697160_1	867845.KI911784_gene2107	4.132e-152	492.0	COG0766@1|root,COG0766@2|Bacteria,2G666@200795|Chloroflexi,374XF@32061|Chloroflexia	32061|Chloroflexia	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
CMS1_k127_2697160_4	383372.Rcas_4390	1.181e-95	324.0	COG1420@1|root,COG1420@2|Bacteria,2G6AQ@200795|Chloroflexi,374VS@32061|Chloroflexia	32061|Chloroflexia	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA
CMS1_k127_2697160_12	926550.CLDAP_31430	3.214e-25	114.0	COG0576@1|root,COG0576@2|Bacteria,2G77I@200795|Chloroflexi	200795|Chloroflexi	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
CMS1_k127_2697160_0	926569.ANT_25050	6.478e-272	849.0	COG0443@1|root,COG0443@2|Bacteria,2G5U5@200795|Chloroflexi	200795|Chloroflexi	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
CMS1_k127_2697160_2	309801.trd_1453	6.993e-108	361.0	COG0484@1|root,COG0484@2|Bacteria,2G5NV@200795|Chloroflexi,27XY0@189775|Thermomicrobia	189775|Thermomicrobia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
CMS1_k127_2697160_3	926550.CLDAP_13110	1.21e-101	340.0	COG1216@1|root,COG1216@2|Bacteria,2G66T@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS1_k127_2697160_14	1330700.JQNC01000003_gene971	3.68e-20	102.0	2E64T@1|root,330TJ@2|Bacteria,1WK59@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2697160_10	479434.Sthe_1446	1.67e-49	192.0	COG1470@1|root,COG1470@2|Bacteria,2G6XR@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF3048) C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3048,DUF3048_C
CMS1_k127_2697160_15	401053.AciPR4_3332	3.805e-15	79.0	COG3536@1|root,COG3536@2|Bacteria,3Y4UI@57723|Acidobacteria,2JJF2@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF971
CMS1_k127_2697160_7	926569.ANT_30490	2.95e-59	214.0	COG0496@1|root,COG0496@2|Bacteria	2|Bacteria	P	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
CMS1_k127_2697160_9	479434.Sthe_1973	2.718e-50	189.0	COG2120@1|root,COG2120@2|Bacteria,2G6YU@200795|Chloroflexi,27YAS@189775|Thermomicrobia	189775|Thermomicrobia	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
CMS1_k127_2697160_8	358681.BBR47_41460	1.073e-51	194.0	COG3375@1|root,COG3375@2|Bacteria,1V21D@1239|Firmicutes,4HG3H@91061|Bacilli,272FA@186822|Paenibacillaceae	91061|Bacilli	M	carboxylic acid catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS1_k127_2697160_11	926550.CLDAP_06850	9.53e-42	158.0	COG5319@1|root,COG5319@2|Bacteria,2GA9G@200795|Chloroflexi	200795|Chloroflexi	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
CMS1_k127_2697160_6	926550.CLDAP_06860	2.306e-71	246.0	COG0194@1|root,COG0194@2|Bacteria,2G6EW@200795|Chloroflexi	200795|Chloroflexi	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
CMS1_k127_2697160_16	198467.NP92_09945	1.503e-13	75.0	COG0457@1|root,COG0705@1|root,COG0457@2|Bacteria,COG0705@2|Bacteria,1TQXT@1239|Firmicutes,4HCDF@91061|Bacilli,21V7J@150247|Anoxybacillus	91061|Bacilli	S	Rhomboid family	gluP	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid,TPR_2,TPR_8
CMS1_k127_2718437_5	1089551.KE386572_gene1566	3.407e-26	111.0	COG2515@1|root,COG2515@2|Bacteria,1MVYF@1224|Proteobacteria,2TRCB@28211|Alphaproteobacteria,4BQG4@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	4.4.1.15,4.4.1.25	ko:K05396,ko:K17950	ko00270,map00270	-	R01874,R07634	RC00382,RC01784	ko00000,ko00001,ko01000	-	-	-	PALP
CMS1_k127_2718437_2	246194.CHY_1273	3.012e-65	233.0	COG1414@1|root,COG1414@2|Bacteria,1TRMW@1239|Firmicutes,24BQA@186801|Clostridia,42G3H@68295|Thermoanaerobacterales	186801|Clostridia	K	Transcriptional regulator IclR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
CMS1_k127_2718437_4	1122915.AUGY01000045_gene2242	2.807e-37	157.0	COG2182@1|root,COG2182@2|Bacteria,1UI6V@1239|Firmicutes,4ISFX@91061|Bacilli,274KA@186822|Paenibacillaceae	91061|Bacilli	G	ABC transporter substrate-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_1,SBP_bac_8
CMS1_k127_2718437_1	935948.KE386494_gene700	9.383e-78	271.0	COG1175@1|root,COG1175@2|Bacteria,1TREE@1239|Firmicutes,24B75@186801|Clostridia,42I1V@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025,ko:K05814	ko02010,map02010	M00198,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.3	-	-	BPD_transp_1
CMS1_k127_2718437_0	373903.Hore_20610	3.379e-78	271.0	COG0395@1|root,COG0395@2|Bacteria,1TRCP@1239|Firmicutes,25C50@186801|Clostridia,3WCAF@53433|Halanaerobiales	186801|Clostridia	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_2718437_3	908612.HMPREF9720_0068	1.093e-56	211.0	COG4409@1|root,COG4409@2|Bacteria,4NIWA@976|Bacteroidetes,2FVT0@200643|Bacteroidia	976|Bacteroidetes	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
CMS1_k127_2720175_7	1303518.CCALI_00021	1.066e-09	67.0	2EATK@1|root,334VC@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2720175_6	113355.CM001775_gene962	2.318e-12	72.0	COG1487@1|root,COG1487@2|Bacteria,1GE3N@1117|Cyanobacteria	2|Bacteria	S	Large family of predicted nucleotide-binding domains	vapC	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
CMS1_k127_2720175_5	406818.XBJ1_4209	3.428e-15	87.0	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,1RPJE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	LU	Rossmann fold nucleotide-binding protein involved in DNA uptake	smf	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
CMS1_k127_2720175_3	882.DVU_2916	3.329e-58	212.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,42PKA@68525|delta/epsilon subdivisions,2WNH0@28221|Deltaproteobacteria,2MBB2@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
CMS1_k127_2720175_0	926550.CLDAP_35470	8.67e-185	613.0	COG3103@1|root,COG3858@1|root,COG3858@2|Bacteria,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	MA20_15015	-	-	-	-	-	-	-	-	-	-	-	DUF1236,SH3_3
CMS1_k127_2720175_2	926550.CLDAP_35490	4.412e-96	333.0	COG2730@1|root,COG3103@1|root,COG2730@2|Bacteria,COG4991@2|Bacteria,2G7Y2@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
CMS1_k127_2720175_4	926550.CLDAP_18930	1.257e-27	115.0	COG0017@1|root,COG0017@2|Bacteria,2G6PN@200795|Chloroflexi	200795|Chloroflexi	J	tRNA synthetase, class II (D, K and N)	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
CMS1_k127_2720175_1	926550.CLDAP_18930	2.959e-114	373.0	COG0017@1|root,COG0017@2|Bacteria,2G6PN@200795|Chloroflexi	200795|Chloroflexi	J	tRNA synthetase, class II (D, K and N)	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
CMS1_k127_2724353_12	926569.ANT_09250	1.175e-67	236.0	COG0642@1|root,COG2205@2|Bacteria,2G6KS@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,GAF,HATPase_c,HisKA
CMS1_k127_2724353_9	443144.GM21_3122	5.251e-94	313.0	COG0745@1|root,COG0745@2|Bacteria,1MU67@1224|Proteobacteria,42N90@68525|delta/epsilon subdivisions,2WJUU@28221|Deltaproteobacteria,43SE9@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	response regulator	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_2724353_23	326427.Cagg_3065	2.949e-16	84.0	COG2204@1|root,COG2204@2|Bacteria,2GAA2@200795|Chloroflexi,3774M@32061|Chloroflexia	32061|Chloroflexia	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS1_k127_2724353_14	3218.PP1S381_17V6.1	3.336e-61	221.0	COG0706@1|root,KOG1239@2759|Eukaryota,37IIV@33090|Viridiplantae,3GB9B@35493|Streptophyta	35493|Streptophyta	OU	Inner membrane protein PPF-1	-	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006605,GO:0006612,GO:0006810,GO:0006886,GO:0006996,GO:0008104,GO:0008150,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0009657,GO:0009668,GO:0009987,GO:0010027,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0017038,GO:0019904,GO:0022607,GO:0031976,GO:0031984,GO:0032991,GO:0033036,GO:0033365,GO:0034357,GO:0034613,GO:0042651,GO:0042886,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0044743,GO:0045036,GO:0045038,GO:0045184,GO:0046907,GO:0050789,GO:0050793,GO:0050794,GO:0051179,GO:0051234,GO:0051259,GO:0051291,GO:0051641,GO:0051649,GO:0055035,GO:0055085,GO:0061024,GO:0065002,GO:0065003,GO:0065007,GO:0070206,GO:0070208,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0072594,GO:0072596,GO:0072598,GO:0072657,GO:0090150,GO:0090342	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
CMS1_k127_2724353_2	316274.Haur_1190	7.88e-215	685.0	COG0531@1|root,COG0531@2|Bacteria,2G5ZF@200795|Chloroflexi,37597@32061|Chloroflexia	200795|Chloroflexi	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
CMS1_k127_2724353_13	1173027.Mic7113_0944	2.942e-65	229.0	COG2204@1|root,COG2204@2|Bacteria,1G623@1117|Cyanobacteria,1HFTT@1150|Oscillatoriales	1117|Cyanobacteria	T	Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,TPR_8
CMS1_k127_2724353_4	867845.KI911784_gene1805	3.612e-131	425.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
CMS1_k127_2724353_7	713586.KB900536_gene1558	1.703e-102	341.0	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,1T4JC@1236|Gammaproteobacteria,1X2UD@135613|Chromatiales	135613|Chromatiales	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
CMS1_k127_2724353_17	309807.SRU_0809	1.813e-52	194.0	COG2430@1|root,COG2430@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF432
CMS1_k127_2724353_20	1173024.KI912149_gene6381	7.41e-38	147.0	COG4891@1|root,COG4891@2|Bacteria,1G7CI@1117|Cyanobacteria	1117|Cyanobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
CMS1_k127_2724353_5	926550.CLDAP_05170	1.164e-110	366.0	COG1284@1|root,COG1284@2|Bacteria,2G6SY@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterized protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
CMS1_k127_2724353_15	926569.ANT_06070	2.19e-57	213.0	COG1181@1|root,COG1181@2|Bacteria,2G5RS@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
CMS1_k127_2724353_0	390874.Tpet_0358	1.53e-311	964.0	COG0500@1|root,COG1181@1|root,COG1181@2|Bacteria,COG2226@2|Bacteria,2GBZA@200918|Thermotogae	200918|Thermotogae	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Methyltransf_25
CMS1_k127_2724353_21	521045.Kole_0198	3.057e-31	134.0	COG1814@1|root,COG1814@2|Bacteria,2GDXP@200918|Thermotogae	200918|Thermotogae	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
CMS1_k127_2724353_10	383372.Rcas_0136	1.907e-84	287.0	COG1378@1|root,COG1378@2|Bacteria,2GANE@200795|Chloroflexi,376UQ@32061|Chloroflexia	32061|Chloroflexia	K	PFAM transcriptional regulator TrmB	-	-	-	-	-	-	-	-	-	-	-	-	Regulator_TrmB,TrmB
CMS1_k127_2724353_3	1449126.JQKL01000003_gene1813	2.465e-209	668.0	COG2414@1|root,COG2414@2|Bacteria,1TPT9@1239|Firmicutes,2481Q@186801|Clostridia,26A1J@186813|unclassified Clostridiales	186801|Clostridia	C	Aldehyde ferredoxin oxidoreductase, N-terminal domain	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
CMS1_k127_2724353_22	926550.CLDAP_39990	1.936e-18	90.0	COG1734@1|root,COG1734@2|Bacteria	2|Bacteria	T	zinc ion binding	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
CMS1_k127_2724353_26	926550.CLDAP_35070	0.0004237	48.0	COG0784@1|root,COG2202@1|root,COG2203@1|root,COG3275@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3275@2|Bacteria,COG4191@2|Bacteria,2G7Y4@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	5TM-5TMR_LYT,GAF_2,HATPase_c,HisKA,HisKA_7TM,PAS,PAS_4,PAS_8,PAS_9,Response_reg
CMS1_k127_2724353_18	879212.DespoDRAFT_01392	1.606e-47	174.0	COG1371@1|root,COG1371@2|Bacteria,1NCP6@1224|Proteobacteria,42VQE@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	PFAM Archease protein family (DUF101 UPF0211)	-	-	-	-	-	-	-	-	-	-	-	-	Archease
CMS1_k127_2724353_1	879212.DespoDRAFT_01391	1.654e-253	787.0	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,42MZN@68525|delta/epsilon subdivisions,2WJGK@28221|Deltaproteobacteria,2MHPF@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Belongs to the RtcB family	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
CMS1_k127_2724353_19	1123057.P872_07670	3.452e-39	155.0	COG1926@1|root,COG1926@2|Bacteria,4NNIW@976|Bacteroidetes,47R4U@768503|Cytophagia	976|Bacteroidetes	S	Phosphoribosyl transferase domain	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	Pribosyltran
CMS1_k127_2724353_11	1121324.CLIT_2c02360	3.915e-68	239.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_25
CMS1_k127_2724353_8	335543.Sfum_1996	3.187e-95	330.0	COG1355@1|root,COG2078@1|root,COG1355@2|Bacteria,COG2078@2|Bacteria,1MXK5@1224|Proteobacteria,42R55@68525|delta/epsilon subdivisions,2WN4E@28221|Deltaproteobacteria,2MQCK@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Memo-like protein	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
CMS1_k127_2724353_16	1499967.BAYZ01000039_gene2221	6.19e-57	205.0	COG1102@1|root,COG1102@2|Bacteria	2|Bacteria	F	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
CMS1_k127_2724353_6	118168.MC7420_528	2.024e-109	365.0	COG2006@1|root,COG2006@2|Bacteria,1G0X0@1117|Cyanobacteria,1HF8Q@1150|Oscillatoriales	1117|Cyanobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
CMS1_k127_2725577_0	118166.JH976537_gene1346	8.056e-126	423.0	COG5421@1|root,COG5421@2|Bacteria,1G4EU@1117|Cyanobacteria,1H9I9@1150|Oscillatoriales	1117|Cyanobacteria	L	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
CMS1_k127_2725577_1	383372.Rcas_1305	4.417e-05	56.0	COG2340@1|root,COG2340@2|Bacteria,2GBMZ@200795|Chloroflexi,3782U@32061|Chloroflexia	32061|Chloroflexia	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2726984_3	1121377.KB906403_gene3138	4.042e-95	316.0	COG0673@1|root,COG0673@2|Bacteria,1WM59@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_2726984_5	41431.PCC8801_1121	8.807e-53	188.0	COG3304@1|root,COG3304@2|Bacteria,1G71Z@1117|Cyanobacteria,3KK41@43988|Cyanothece	1117|Cyanobacteria	S	Inner membrane component domain	-	-	-	-	-	-	-	-	-	-	-	-	YccF
CMS1_k127_2726984_0	526227.Mesil_0256	6.853e-213	710.0	COG0457@1|root,COG1672@1|root,COG2114@1|root,COG0457@2|Bacteria,COG1672@2|Bacteria,COG2114@2|Bacteria	2|Bacteria	T	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,CHAT,Guanylate_cyc,TPR_10,TPR_12,TPR_8
CMS1_k127_2726984_4	1128427.KB904821_gene2143	7.873e-61	216.0	COG0406@1|root,COG0406@2|Bacteria,1G0NK@1117|Cyanobacteria,1H7MJ@1150|Oscillatoriales	1117|Cyanobacteria	G	phosphoglycerate mutase	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
CMS1_k127_2726984_6	324602.Caur_2285	4.497e-45	166.0	COG3254@1|root,COG3254@2|Bacteria,2G9IM@200795|Chloroflexi,3778J@32061|Chloroflexia	32061|Chloroflexia	S	Pfam:DUF718	-	-	5.1.3.32	ko:K03534	-	-	R10819	RC00563	ko00000,ko01000	-	-	-	rhaM
CMS1_k127_2726984_1	1121904.ARBP01000026_gene694	3.02e-187	591.0	COG0673@1|root,COG0673@2|Bacteria,4NJ92@976|Bacteroidetes,47MAS@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_2726984_2	357808.RoseRS_2514	8.375e-113	371.0	COG4821@1|root,COG4821@2|Bacteria,2G6XP@200795|Chloroflexi	200795|Chloroflexi	S	SIS domain	-	-	-	-	-	-	-	-	-	-	-	-	SIS_2
CMS1_k127_2726984_7	391735.Veis_2457	1.754e-28	120.0	COG1028@1|root,COG1028@2|Bacteria,1NTI2@1224|Proteobacteria,2VQ4K@28216|Betaproteobacteria,4AJQ5@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS1_k127_2736072_13	5037.XP_001541271.1	0.0007206	52.0	COG2304@1|root,2REND@2759|Eukaryota,38TNH@33154|Opisthokonta,3P1BG@4751|Fungi,3QSME@4890|Ascomycota,20EE5@147545|Eurotiomycetes,3B1G2@33183|Onygenales	4751|Fungi	S	Hint-domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2,VWA_3,Vint,Vwaint
CMS1_k127_2736072_12	1318628.MARLIPOL_09971	2.168e-11	76.0	COG1372@1|root,COG1520@1|root,COG3209@1|root,COG1372@2|Bacteria,COG1520@2|Bacteria,COG3209@2|Bacteria,1QW4H@1224|Proteobacteria,1T42N@1236|Gammaproteobacteria,46DDZ@72275|Alteromonadaceae	1236|Gammaproteobacteria	LM	Rhs Family	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,DUF5122,He_PIG,PT-HINT,RHS_repeat
CMS1_k127_2736072_3	1255043.TVNIR_3076	5.974e-98	334.0	2EQH8@1|root,33I38@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2736072_6	926550.CLDAP_06250	2.566e-52	203.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,MFS_1
CMS1_k127_2736072_8	926550.CLDAP_20100	5.377e-41	163.0	COG0723@1|root,COG0723@2|Bacteria,2G7BG@200795|Chloroflexi	200795|Chloroflexi	C	Rieske [2Fe-2S] domain	-	-	1.10.9.1	ko:K02636	ko00195,ko01100,map00195,map01100	M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Rieske
CMS1_k127_2736072_0	926550.CLDAP_20090	2.028e-156	511.0	COG1290@1|root,COG1290@2|Bacteria	2|Bacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petB	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_3585	Cytochrom_B_C,Cytochrom_B_N_2,Cytochrome_B
CMS1_k127_2736072_7	926550.CLDAP_20080	2.482e-49	184.0	COG2010@1|root,COG2010@2|Bacteria,2G9TS@200795|Chloroflexi	2|Bacteria	C	Cytochrome c	-	-	-	ko:K17222	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C,Cytochrome_CBB3
CMS1_k127_2736072_10	1382306.JNIM01000001_gene2679	1.597e-21	98.0	COG3255@1|root,COG3255@2|Bacteria,2G7E8@200795|Chloroflexi	200795|Chloroflexi	I	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
CMS1_k127_2736072_9	401526.TcarDRAFT_1947	1.223e-21	104.0	COG2340@1|root,COG2340@2|Bacteria,1V6GZ@1239|Firmicutes,4H4BG@909932|Negativicutes	909932|Negativicutes	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
CMS1_k127_2736072_4	1382306.JNIM01000001_gene171	1.311e-83	285.0	COG2362@1|root,COG2362@2|Bacteria,2G8M4@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M55 D-aminopeptidase	-	-	-	ko:K16203	-	-	-	-	ko00000,ko01000,ko01002	3.A.1.5.2	-	-	Peptidase_M55
CMS1_k127_2736072_5	1382306.JNIM01000001_gene1621	3.84e-68	259.0	COG0515@1|root,COG0515@2|Bacteria	1382306.JNIM01000001_gene1621|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2736072_1	221288.JH992901_gene3416	3.226e-103	365.0	COG1672@1|root,COG1672@2|Bacteria,1G0F4@1117|Cyanobacteria	1117|Cyanobacteria	K	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	AAA_35,CHAT,TIR_2
CMS1_k127_2736072_2	221288.JH992901_gene3415	6.923e-101	361.0	COG1672@1|root,COG2319@1|root,COG1672@2|Bacteria,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1JJ8I@1189|Stigonemataceae	1117|Cyanobacteria	S	AAA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_35,WD40
CMS1_k127_2736072_11	1120963.KB894494_gene3419	4.604e-14	87.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,1MX41@1224|Proteobacteria,1RP38@1236|Gammaproteobacteria,2Q0BE@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	M	Tricorn protease homolog	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
CMS1_k127_274336_0	485913.Krac_7480	8.321e-83	308.0	COG3629@1|root,COG3629@2|Bacteria	2|Bacteria	K	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
CMS1_k127_2745960_5	1089553.Tph_c02320	0.0001828	53.0	COG3103@1|root,COG3103@2|Bacteria,1VN3X@1239|Firmicutes,24W72@186801|Clostridia	186801|Clostridia	T	Bacterial SH3 domain	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
CMS1_k127_2745960_4	585.DR95_2405	3.931e-17	94.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,1RMGA@1236|Gammaproteobacteria,3Z1QQ@583|Proteus	1236|Gammaproteobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	GO:0003674,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
CMS1_k127_2745960_2	1232410.KI421428_gene1058	2.073e-53	199.0	COG1341@1|root,COG1341@2|Bacteria,1NBYH@1224|Proteobacteria,42THE@68525|delta/epsilon subdivisions,2WR2N@28221|Deltaproteobacteria,43VXS@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	mRNA cleavage and polyadenylation factor CLP1 P-loop	-	-	-	ko:K06947	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	CLP1_P
CMS1_k127_2745960_3	525904.Tter_0301	8.668e-48	192.0	COG2203@1|root,COG3284@1|root,COG4585@1|root,COG2203@2|Bacteria,COG3284@2|Bacteria,COG4585@2|Bacteria,2NPMD@2323|unclassified Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07777,ko:K19661,ko:K21405	ko02020,map02020	M00478,M00772	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko03000	-	-	-	GAF,GAF_2,HATPase_c,HisKA,HisKA_3,Lactamase_B_2,PAS,PAS_4,PAS_9
CMS1_k127_2745960_1	1121382.JQKG01000017_gene1858	1.417e-71	249.0	COG2197@1|root,COG2197@2|Bacteria,1WI4W@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS1_k127_2745960_0	926569.ANT_16230	1.228e-71	250.0	COG0621@1|root,COG0621@2|Bacteria,2G5UI@200795|Chloroflexi	200795|Chloroflexi	J	modification enzyme, MiaB family	-	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
CMS1_k127_2747961_4	926550.CLDAP_04460	6.35e-06	55.0	COG1807@1|root,COG1807@2|Bacteria,2G8YZ@200795|Chloroflexi	200795|Chloroflexi	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2747961_2	1306990.BARG01000031_gene3485	1.181e-42	165.0	COG1028@1|root,COG1028@2|Bacteria,2GM3I@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
CMS1_k127_2747961_0	926569.ANT_27190	9.457e-225	711.0	COG1132@1|root,COG1132@2|Bacteria	2|Bacteria	V	(ABC) transporter	mdlB	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS1_k127_2747961_1	1455608.JDTH01000002_gene1803	4.626e-129	429.0	COG0534@1|root,arCOG01731@2157|Archaea,2XU54@28890|Euryarchaeota,23RX7@183963|Halobacteria	183963|Halobacteria	V	COG0534 Na -driven multidrug efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	MatE
CMS1_k127_2747961_3	485913.Krac_3086	1.521e-12	71.0	COG1846@1|root,COG1846@2|Bacteria,2G9S8@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional regulator, MarR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27
CMS1_k127_2765162_3	756067.MicvaDRAFT_2506	1.145e-45	173.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1H9T8@1150|Oscillatoriales	1117|Cyanobacteria	Q	Amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
CMS1_k127_2765162_2	316274.Haur_3300	1.187e-113	378.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
CMS1_k127_2765162_0	1173023.KE650771_gene5337	0.0	1226.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1JK4D@1189|Stigonemataceae	1117|Cyanobacteria	Q	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
CMS1_k127_2765162_1	1469607.KK073767_gene214	8.932e-171	549.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1HMS5@1161|Nostocales	1117|Cyanobacteria	Q	Condensation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_12,Methyltransf_25,PP-binding,Thioesterase
CMS1_k127_2768387_3	357808.RoseRS_2972	1.542e-85	287.0	COG1960@1|root,COG1960@2|Bacteria,2G8BF@200795|Chloroflexi,3763I@32061|Chloroflexia	32061|Chloroflexia	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS1_k127_2768387_0	926550.CLDAP_39110	4.984e-162	520.0	COG1960@1|root,COG1960@2|Bacteria,2G6E5@200795|Chloroflexi	200795|Chloroflexi	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS1_k127_2768387_2	926550.CLDAP_37110	3.582e-105	347.0	COG1028@1|root,COG1028@2|Bacteria	926550.CLDAP_37110|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2768387_1	316274.Haur_4394	1.814e-121	397.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,2G65G@200795|Chloroflexi,374V3@32061|Chloroflexia	32061|Chloroflexia	I	PFAM Enoyl-CoA hydratase isomerase	-	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1,ECH_2
CMS1_k127_2773924_10	525904.Tter_1162	3.867e-11	63.0	COG2924@1|root,COG2924@2|Bacteria,2NRHF@2323|unclassified Bacteria	2|Bacteria	CO	Bacterial Fe(2+) trafficking	yggX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0033554,GO:0034599,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0070887	-	-	-	-	-	-	-	-	-	-	Iron_traffic
CMS1_k127_2773924_2	485913.Krac_1190	2.891e-154	498.0	COG0151@1|root,COG0151@2|Bacteria,2G7M4@200795|Chloroflexi	200795|Chloroflexi	F	carboxylate-amine ligase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4
CMS1_k127_2773924_12	4098.XP_009595559.1	4.851e-05	46.0	COG0388@1|root,KOG0805@2759|Eukaryota,37R5R@33090|Viridiplantae,3GAKT@35493|Streptophyta,44F3F@71274|asterids	35493|Streptophyta	E	Bifunctional nitrilase nitrile hydratase	NIT1	GO:0000257,GO:0003674,GO:0003824,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005911,GO:0006082,GO:0006725,GO:0006790,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009267,GO:0009506,GO:0009507,GO:0009536,GO:0009605,GO:0009636,GO:0009683,GO:0009684,GO:0009850,GO:0009851,GO:0009970,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0010817,GO:0016020,GO:0016053,GO:0016143,GO:0016145,GO:0016787,GO:0016810,GO:0016815,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0018822,GO:0019438,GO:0019499,GO:0019748,GO:0019752,GO:0019757,GO:0019759,GO:0019760,GO:0019762,GO:0030054,GO:0031667,GO:0031668,GO:0031669,GO:0032787,GO:0033554,GO:0034641,GO:0034754,GO:0042221,GO:0042430,GO:0042435,GO:0042445,GO:0042446,GO:0042594,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044248,GO:0044249,GO:0044271,GO:0044273,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046686,GO:0047427,GO:0047558,GO:0048046,GO:0050896,GO:0051410,GO:0051716,GO:0055044,GO:0065007,GO:0065008,GO:0071496,GO:0071704,GO:0071944,GO:0072330,GO:0080061,GO:0080109,GO:0098754,GO:1901135,GO:1901136,GO:1901360,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901698	3.5.5.1,3.5.5.4,4.2.1.65	ko:K01501,ko:K13035	ko00380,ko00460,ko00627,ko00643,ko00910,ko01100,ko01110,ko01120,map00380,map00460,map00627,map00643,map00910,map01100,map01110,map01120	-	R00486,R00540,R01267,R01887,R03093,R03542,R05591,R07855	RC00315,RC00325,RC00483,RC00617,RC00959,RC02811	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
CMS1_k127_2773924_6	357808.RoseRS_0893	3.478e-19	89.0	COG3677@1|root,COG3677@2|Bacteria,2G6SJ@200795|Chloroflexi,3772U@32061|Chloroflexia	32061|Chloroflexia	L	PFAM Transposase IS66 family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2773924_4	1521187.JPIM01000048_gene77	8.807e-52	192.0	COG3677@1|root,COG3677@2|Bacteria,2G6SJ@200795|Chloroflexi,3772U@32061|Chloroflexia	32061|Chloroflexia	L	PFAM Transposase IS66 family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2773924_3	869210.Marky_0025	1.222e-86	294.0	COG1028@1|root,COG1028@2|Bacteria,1WIJY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	IQ	COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase)	-	-	1.1.1.30	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	M00088	R01361	RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short_C2
CMS1_k127_2773924_11	1172179.AUKV01000001_gene1157	9.544e-06	57.0	COG3420@1|root,COG3420@2|Bacteria,2GNYS@201174|Actinobacteria	201174|Actinobacteria	P	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
CMS1_k127_2773924_9	316055.RPE_0847	1.138e-13	72.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,3JTDD@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	MA20_18835	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
CMS1_k127_2773924_7	68570.DC74_7296	1.299e-16	83.0	2BUTG@1|root,32Q51@2|Bacteria,2ISEW@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2773924_1	1128421.JAGA01000003_gene3678	2.157e-169	583.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2NQCZ@2323|unclassified Bacteria	2|Bacteria	K	NB-ARC domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_22,BTAD,NB-ARC,TPR_10,TPR_12,TPR_8,Trans_reg_C
CMS1_k127_2773924_5	1122939.ATUD01000013_gene869	6.374e-47	196.0	COG0515@1|root,COG0515@2|Bacteria,2GNG1@201174|Actinobacteria,4CPQV@84995|Rubrobacteria	84995|Rubrobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS1_k127_2773924_8	1121937.AUHJ01000005_gene2248	1.81e-16	81.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,1RMQ4@1236|Gammaproteobacteria,4654E@72275|Alteromonadaceae	1236|Gammaproteobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
CMS1_k127_2773924_0	1128421.JAGA01000002_gene1399	1.603e-193	615.0	COG1032@1|root,COG1032@2|Bacteria,2NQJQ@2323|unclassified Bacteria	2|Bacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
CMS1_k127_2774359_2	926550.CLDAP_40710	0.0006697	45.0	2EU9B@1|root,33MRR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2774359_1	926550.CLDAP_13010	1.264e-58	216.0	COG3629@1|root,COG3629@2|Bacteria	2|Bacteria	K	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Abhydrolase_1,BTAD,TPR_12,Trans_reg_C
CMS1_k127_2774359_0	926550.CLDAP_39790	6.75e-187	596.0	COG1164@1|root,COG1164@2|Bacteria,2G5JB@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M3A and M3B, thimet oligopeptidase F	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
CMS1_k127_2779850_3	196162.Noca_2162	8.384e-46	173.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria,4DNZX@85009|Propionibacteriales	201174|Actinobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
CMS1_k127_2779850_1	314262.MED193_18074	4.368e-66	234.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,2TQK1@28211|Alphaproteobacteria,2P27B@2433|Roseobacter	28211|Alphaproteobacteria	E	COG0411 ABC-type branched-chain amino acid transport systems, ATPase component	-	-	-	ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
CMS1_k127_2779850_0	383372.Rcas_2298	2.417e-74	258.0	COG0410@1|root,COG0410@2|Bacteria,2G69M@200795|Chloroflexi,374YI@32061|Chloroflexia	32061|Chloroflexia	E	PFAM ABC transporter related	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
CMS1_k127_2779850_2	717231.Flexsi_1534	8.016e-63	226.0	COG0559@1|root,COG0559@2|Bacteria,2GF8D@200930|Deferribacteres	2|Bacteria	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997,ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
CMS1_k127_2779850_4	383372.Rcas_2301	3.574e-45	176.0	COG4177@1|root,COG4177@2|Bacteria,2G8KF@200795|Chloroflexi	200795|Chloroflexi	E	transport system permease	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
CMS1_k127_2779850_5	1448860.BBJO01000042_gene1758	9.15e-41	163.0	COG0683@1|root,arCOG01020@2157|Archaea,2XVWV@28890|Euryarchaeota,23UWK@183963|Halobacteria	183963|Halobacteria	E	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
CMS1_k127_2782552_3	1499967.BAYZ01000177_gene5755	2.352e-70	240.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2NNS9@2323|unclassified Bacteria	2|Bacteria	EU	peptidase S9 prolyl oligopeptidase active site	yuxL	-	3.4.19.1	ko:K01303	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S9
CMS1_k127_2782552_4	472759.Nhal_1064	3.411e-56	200.0	COG4067@1|root,COG4067@2|Bacteria,1RGX8@1224|Proteobacteria,1S5YR@1236|Gammaproteobacteria,1WYD4@135613|Chromatiales	135613|Chromatiales	O	Putative ATP-dependant zinc protease	-	-	-	-	-	-	-	-	-	-	-	-	Zn_protease
CMS1_k127_2782552_0	572477.Alvin_1979	1.404e-152	489.0	COG0189@1|root,COG0189@2|Bacteria,1MX62@1224|Proteobacteria,1RM8B@1236|Gammaproteobacteria,1WX7Z@135613|Chromatiales	135613|Chromatiales	HJ	Belongs to the RimK family	rimK	-	-	ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RimK
CMS1_k127_2782552_1	661478.OP10G_1498	1.605e-113	372.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
CMS1_k127_2782552_5	1089550.ATTH01000001_gene789	5.244e-07	56.0	2AB6W@1|root,310M7@2|Bacteria,4PF7N@976|Bacteroidetes,1FK98@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2782552_2	608538.HTH_0399	1.035e-92	320.0	COG0683@1|root,COG0683@2|Bacteria,2G4XD@200783|Aquificae	200783|Aquificae	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
CMS1_k127_2782552_6	748224.HMPREF9436_00089	0.0006591	45.0	COG0559@1|root,COG0559@2|Bacteria,1TR24@1239|Firmicutes,2480A@186801|Clostridia,3WGTF@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997,ko:K11960	ko02010,ko02024,map02010,map02024	M00237,M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4,3.A.1.4.4,3.A.1.4.5	-	-	BPD_transp_2
CMS1_k127_2784448_7	1341151.ASZU01000003_gene2663	3.428e-30	124.0	COG0508@1|root,COG0508@2|Bacteria,1TQSH@1239|Firmicutes,4HBSU@91061|Bacilli,27BET@186824|Thermoactinomycetaceae	91061|Bacilli	C	2-oxoacid dehydrogenases acyltransferase (catalytic domain)	bkdB	-	2.3.1.12,2.3.1.168	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	M00036,M00307	R00209,R02569,R02662,R03174,R04097,R10998	RC00004,RC02727,RC02742,RC02857,RC02870	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
CMS1_k127_2784448_2	326427.Cagg_2096	1.332e-140	453.0	COG0022@1|root,COG0022@2|Bacteria,2G5JU@200795|Chloroflexi,374SG@32061|Chloroflexia	32061|Chloroflexia	C	PFAM Transketolase central region	-	-	1.2.4.4	ko:K00167	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
CMS1_k127_2784448_4	1120973.AQXL01000131_gene2037	1.03e-100	338.0	COG1071@1|root,COG1071@2|Bacteria,1TQDG@1239|Firmicutes,4HBEQ@91061|Bacilli,278XF@186823|Alicyclobacillaceae	91061|Bacilli	C	Dehydrogenase E1 component	bfmBAA	-	1.2.4.4	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS07640	E1_dh
CMS1_k127_2784448_0	926550.CLDAP_03390	2.089e-252	795.0	COG0247@1|root,COG2181@1|root,COG0247@2|Bacteria,COG2181@2|Bacteria,2G5X6@200795|Chloroflexi	200795|Chloroflexi	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8,Nitrate_red_gam
CMS1_k127_2784448_6	926550.CLDAP_35190	2.584e-33	132.0	2FKJC@1|root,34C6D@2|Bacteria,2G9T3@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2784448_3	926550.CLDAP_04560	3.833e-107	360.0	COG0438@1|root,COG0438@2|Bacteria,2G5QJ@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS1_k127_2784448_5	926550.CLDAP_04630	2.07e-77	273.0	COG0438@1|root,COG0438@2|Bacteria,2G7W6@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CMS1_k127_2784448_1	926550.CLDAP_06140	4.776e-168	532.0	COG1087@1|root,COG1087@2|Bacteria,2G5QM@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
CMS1_k127_2787965_7	754027.HMPREF9554_03094	1.71e-55	202.0	COG2227@1|root,COG2227@2|Bacteria,2J59U@203691|Spirochaetes	203691|Spirochaetes	H	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS1_k127_2787965_8	309801.trd_0680	1.626e-39	154.0	COG0250@1|root,COG0250@2|Bacteria,2G6A3@200795|Chloroflexi,27XZ9@189775|Thermomicrobia	189775|Thermomicrobia	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
CMS1_k127_2787965_4	1408422.JHYF01000009_gene2119	1.988e-82	288.0	COG0001@1|root,COG0001@2|Bacteria,1UJF0@1239|Firmicutes,24KWI@186801|Clostridia,36RM6@31979|Clostridiaceae	186801|Clostridia	H	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
CMS1_k127_2787965_0	926550.CLDAP_40130	5.244e-230	721.0	COG1129@1|root,COG1129@2|Bacteria,2G649@200795|Chloroflexi	200795|Chloroflexi	P	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system	rbsA	-	3.6.3.17	ko:K10562	ko02010,map02010	M00220	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.9	-	-	ABC_tran
CMS1_k127_2787965_6	314345.SPV1_10561	4.139e-65	224.0	COG4802@1|root,COG4802@2|Bacteria,1NW4K@1224|Proteobacteria	1224|Proteobacteria	C	Ferredoxin thioredoxin reductase catalytic beta chain	-	-	1.8.7.2	ko:K17892	-	-	-	-	ko00000,ko01000	-	-	-	FeThRed_B
CMS1_k127_2787965_3	926550.CLDAP_40120	1.772e-132	431.0	COG1172@1|root,COG1172@2|Bacteria,2G6EY@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10560	ko02010,map02010	M00220	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.9	-	-	BPD_transp_2
CMS1_k127_2787965_2	324602.Caur_2287	8.674e-136	440.0	COG1172@1|root,COG1172@2|Bacteria,2G6DF@200795|Chloroflexi,376MT@32061|Chloroflexia	32061|Chloroflexia	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10561	ko02010,map02010	M00220	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.9	-	-	BPD_transp_2
CMS1_k127_2787965_1	926550.CLDAP_40100	8.501e-172	545.0	COG1879@1|root,COG1879@2|Bacteria,2G8BJ@200795|Chloroflexi	200795|Chloroflexi	G	Periplasmic binding protein domain	-	-	-	ko:K10559	ko02010,map02010	M00220	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.9	-	-	Peripla_BP_4
CMS1_k127_2787965_5	926550.CLDAP_07110	1.828e-76	259.0	COG0457@1|root,COG0457@2|Bacteria,2G76G@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF4037)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4037
CMS1_k127_2791109_2	383372.Rcas_0265	3.135e-76	271.0	COG0596@1|root,COG0596@2|Bacteria,2G6Y2@200795|Chloroflexi	200795|Chloroflexi	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
CMS1_k127_2791109_0	485913.Krac_3682	9.304e-171	544.0	COG0673@1|root,COG0673@2|Bacteria,2G7RI@200795|Chloroflexi	200795|Chloroflexi	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_2791109_3	1267535.KB906767_gene4476	7.591e-75	261.0	COG1082@1|root,COG1082@2|Bacteria,3Y69B@57723|Acidobacteria,2JM08@204432|Acidobacteriia	204432|Acidobacteriia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS1_k127_2791109_1	313603.FB2170_11716	1.581e-130	428.0	COG1486@1|root,COG1486@2|Bacteria	2|Bacteria	G	melibiose metabolic process	-	-	3.2.1.22,3.2.1.86	ko:K01222,ko:K07406	ko00010,ko00052,ko00500,ko00561,ko00600,ko00603,map00010,map00052,map00500,map00561,map00600,map00603	-	R00839,R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05133,R05134,R05549,R05961,R06091	RC00049,RC00059,RC00171,RC00451,RC00714	ko00000,ko00001,ko01000	-	GT4	-	Glyco_hydro_4,Glyco_hydro_4C
CMS1_k127_279714_2	278957.ABEA03000182_gene1973	1.964e-17	82.0	COG0702@1|root,COG0702@2|Bacteria,46YBQ@74201|Verrucomicrobia,3K8MJ@414999|Opitutae	414999|Opitutae	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
CMS1_k127_279714_0	1499967.BAYZ01000026_gene1631	4.79e-107	372.0	COG0367@1|root,COG0367@2|Bacteria,2NNKE@2323|unclassified Bacteria	2|Bacteria	E	PFAM asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
CMS1_k127_279714_1	1210908.HSB1_32670	9.02e-22	110.0	arCOG00567@1|root,arCOG00567@2157|Archaea,2XVU1@28890|Euryarchaeota,23UZV@183963|Halobacteria	183963|Halobacteria	M	glycosyl transferase family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS1_k127_2797277_2	316274.Haur_3578	6.61e-54	203.0	COG2199@1|root,COG3944@1|root,COG2199@2|Bacteria,COG3944@2|Bacteria,2GBA7@200795|Chloroflexi,377N2@32061|Chloroflexia	32061|Chloroflexia	M	lipopolysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzz
CMS1_k127_2797277_1	1500257.JQNM01000022_gene2687	1.61e-88	298.0	COG2220@1|root,COG2220@2|Bacteria,1MVP2@1224|Proteobacteria,2U2W2@28211|Alphaproteobacteria,4BAGJ@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
CMS1_k127_2802150_1	383372.Rcas_1882	3.658e-152	494.0	COG4888@1|root,COG4888@2|Bacteria,2G838@200795|Chloroflexi	200795|Chloroflexi	S	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
CMS1_k127_2802150_0	926550.CLDAP_17980	3.857e-172	552.0	COG3669@1|root,COG3669@2|Bacteria,2G85R@200795|Chloroflexi	200795|Chloroflexi	G	Alpha-L-fucosidase C-terminal domain	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Fucosidase_C
CMS1_k127_2802150_2	1303518.CCALI_01537	7.746e-125	408.0	COG1063@1|root,COG1063@2|Bacteria	2|Bacteria	E	alcohol dehydrogenase	-	-	1.1.1.380	ko:K08322	ko00040,ko01100,map00040,map01100	-	R10848	RC00085	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_2802150_3	1382306.JNIM01000001_gene2963	3.705e-27	114.0	COG2140@1|root,COG2140@2|Bacteria,2G9AT@200795|Chloroflexi	200795|Chloroflexi	G	Glucose-6-phosphate isomerase (GPI)	-	-	5.3.1.9	ko:K06859	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	GPI
CMS1_k127_2803388_0	1254432.SCE1572_37375	1.848e-163	529.0	COG0122@1|root,COG2169@1|root,COG0122@2|Bacteria,COG2169@2|Bacteria,1QTXM@1224|Proteobacteria,42N8C@68525|delta/epsilon subdivisions,2WM3N@28221|Deltaproteobacteria,2YUFY@29|Myxococcales	28221|Deltaproteobacteria	K	AlkA N-terminal domain	-	-	3.2.2.21	ko:K13529,ko:K13530	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,AlkA_N,HTH_18,HhH-GPD
CMS1_k127_2803388_1	1068980.ARVW01000001_gene6489	3.955e-113	379.0	COG0477@1|root,COG2814@2|Bacteria,2IDPG@201174|Actinobacteria	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
CMS1_k127_2803388_2	330214.NIDE0745	7.384e-60	219.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS1_k127_2804263_5	926550.CLDAP_27520	5.951e-98	329.0	COG0318@1|root,COG0318@2|Bacteria	2|Bacteria	IQ	PFAM AMP-dependent synthetase and ligase	menE	-	6.2.1.26	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04030	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C
CMS1_k127_2804263_4	742726.HMPREF9448_01309	2.224e-114	378.0	COG4948@1|root,COG4948@2|Bacteria,4NEBX@976|Bacteroidetes,2FMXR@200643|Bacteroidia,22X1A@171551|Porphyromonadaceae	976|Bacteroidetes	M	Mandelate racemase muconate lactonizing enzyme	menC	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C
CMS1_k127_2804263_2	926549.KI421517_gene3815	4.781e-155	492.0	COG0447@1|root,COG0447@2|Bacteria,4NDXT@976|Bacteroidetes,47JYS@768503|Cytophagia	976|Bacteroidetes	H	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)	menB	-	4.1.3.36	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07263	RC01923	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
CMS1_k127_2804263_1	926550.CLDAP_22850	2.08e-180	582.0	COG1165@1|root,COG1165@2|Bacteria,2G6JR@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	-	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M_2,TPP_enzyme_N
CMS1_k127_2804263_3	926550.CLDAP_22860	1.691e-120	399.0	COG1169@1|root,COG1169@2|Bacteria	2|Bacteria	HQ	isochorismate synthase activity	menF	GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004049,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008909,GO:0009058,GO:0009072,GO:0009073,GO:0009108,GO:0009233,GO:0009234,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0016853,GO:0016866,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042180,GO:0042181,GO:0042401,GO:0042430,GO:0042435,GO:0043167,GO:0043169,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0046872,GO:0050486,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901661,GO:1901663,GO:1902494	5.4.4.2	ko:K02361,ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	iECABU_c1320.ECABU_c26010,iECIAI39_1322.ECIAI39_2413,iSF_1195.SF2344,iS_1188.S2478,ic_1306.c2809	Chorismate_bind
CMS1_k127_2804263_9	313606.M23134_04481	2.769e-48	176.0	COG2050@1|root,COG2050@2|Bacteria,4NNYG@976|Bacteroidetes,47QEZ@768503|Cytophagia	976|Bacteroidetes	Q	PFAM thioesterase superfamily	ydiI	-	3.1.2.28	ko:K19222	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07262	RC00004,RC00174	ko00000,ko00001,ko00002,ko01000	-	-	-	4HBT,Hydrolase_3
CMS1_k127_2804263_8	926550.CLDAP_15330	8.429e-64	226.0	COG0500@1|root,COG2226@2|Bacteria,2G6T6@200795|Chloroflexi	200795|Chloroflexi	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
CMS1_k127_2804263_6	926550.CLDAP_15340	7.473e-84	284.0	COG0500@1|root,COG2226@2|Bacteria,2G780@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS1_k127_2804263_10	301.JNHE01000001_gene179	2.871e-22	101.0	COG2197@1|root,COG2199@1|root,COG2197@2|Bacteria,COG3706@2|Bacteria,1MVNV@1224|Proteobacteria,1RQHK@1236|Gammaproteobacteria,1YHQP@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	K	helix_turn_helix, Lux Regulon	luxR	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS1_k127_2804263_0	926550.CLDAP_15350	7.036e-295	941.0	COG0744@1|root,COG0744@2|Bacteria,2G5ZG@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase, family 51	-	-	-	-	-	-	-	-	-	-	-	-	BiPBP_C,Transgly,Transpeptidase
CMS1_k127_2804263_7	99598.Cal7507_1790	1.217e-69	245.0	28I2M@1|root,2Z85A@2|Bacteria,1G2QZ@1117|Cyanobacteria,1HU7I@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function (DUF4058)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4058
CMS1_k127_2804263_12	102129.Lepto7375DRAFT_2279	1.166e-06	50.0	COG0515@1|root,COG5635@1|root,COG0515@2|Bacteria,COG5635@2|Bacteria,1G14T@1117|Cyanobacteria,1H8RF@1150|Oscillatoriales	1117|Cyanobacteria	T	Ntpase (Nacht family)	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	NACHT,Pkinase,TIR_2
CMS1_k127_2804263_11	1121377.KB906404_gene2858	1.675e-20	94.0	COG3393@1|root,COG3393@2|Bacteria	2|Bacteria	S	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3,FR47,GNAT_acetyltran
CMS1_k127_2813495_2	63737.Npun_F6039	8.837e-57	209.0	COG1100@1|root,COG4886@1|root,COG1100@2|Bacteria,COG4886@2|Bacteria,1G05B@1117|Cyanobacteria,1HJS7@1161|Nostocales	1117|Cyanobacteria	S	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,COR,LRR_4,LRR_8,Roc,TIR_2
CMS1_k127_2813495_0	880072.Desac_2878	8.791e-76	264.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,42MFP@68525|delta/epsilon subdivisions,2WJ47@28221|Deltaproteobacteria,2MQ6J@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
CMS1_k127_2813495_1	1499967.BAYZ01000054_gene4817	7.863e-75	264.0	COG0601@1|root,COG0601@2|Bacteria	2|Bacteria	P	nitrogen compound transport	appB	GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0022857,GO:0051179,GO:0051234,GO:0055085	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_2818249_0	926569.ANT_22870	9.672e-153	493.0	COG0213@1|root,COG0213@2|Bacteria,2G64G@200795|Chloroflexi	200795|Chloroflexi	F	PFAM glycosyl transferase family 3	pdp	-	2.4.2.2	ko:K00756	ko00240,ko01100,map00240,map01100	-	R01570,R01876,R02296,R02484	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
CMS1_k127_2818249_3	1487953.JMKF01000006_gene5651	7.444e-48	175.0	COG3238@1|root,COG3238@2|Bacteria	2|Bacteria	S	Putative inner membrane exporter, YdcZ	-	-	-	ko:K09936	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.A.7.21	-	-	DMT_YdcZ
CMS1_k127_2818249_4	383372.Rcas_2223	1.106e-47	175.0	COG1490@1|root,COG1490@2|Bacteria,2G6P5@200795|Chloroflexi,37741@32061|Chloroflexia	32061|Chloroflexia	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
CMS1_k127_2818249_8	102125.Xen7305DRAFT_00051470	4.897e-05	55.0	COG0457@1|root,COG0457@2|Bacteria,1GF41@1117|Cyanobacteria	1117|Cyanobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_2
CMS1_k127_2818249_6	383372.Rcas_0607	2.457e-41	162.0	COG0561@1|root,COG0561@2|Bacteria,2G74S@200795|Chloroflexi,377A0@32061|Chloroflexia	32061|Chloroflexia	S	Haloacid dehalogenase domain protein hydrolase, type 3	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
CMS1_k127_2818249_5	1231057.AMGD01000082_gene926	2.25e-44	168.0	COG0009@1|root,COG0009@2|Bacteria,1TP1I@1239|Firmicutes,4HA7W@91061|Bacilli,26DDK@186818|Planococcaceae	91061|Bacilli	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	ywlC	GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
CMS1_k127_2818249_7	394503.Ccel_3359	4.332e-06	56.0	2EY8W@1|root,33RHE@2|Bacteria,1VRH4@1239|Firmicutes,25DWM@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2818249_1	765420.OSCT_1715	8.164e-95	323.0	COG0438@1|root,COG0438@2|Bacteria,2G5N9@200795|Chloroflexi,3755Z@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS1_k127_2818249_2	1128421.JAGA01000001_gene2254	1.643e-58	214.0	COG0859@1|root,COG0859@2|Bacteria,2NQXU@2323|unclassified Bacteria	2|Bacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
CMS1_k127_2837225_3	324602.Caur_2690	3.934e-05	46.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Usp
CMS1_k127_2837225_0	452637.Oter_2033	1.615e-136	450.0	COG2268@1|root,COG2268@2|Bacteria,46TRR@74201|Verrucomicrobia,3K887@414999|Opitutae	414999|Opitutae	S	prohibitin homologues	-	-	-	ko:K07192	ko04910,map04910	-	-	-	ko00000,ko00001,ko03036,ko04131,ko04147	-	-	-	Band_7
CMS1_k127_2837225_2	671143.DAMO_0980	2.566e-09	59.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2NP1J@2323|unclassified Bacteria	2|Bacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_13,Fer4_6,PFOR_II,POR,POR_N,TPP_enzyme_C
CMS1_k127_285350_0	383372.Rcas_2574	3.848e-62	246.0	COG1572@1|root,COG3386@1|root,COG1572@2|Bacteria,COG3386@2|Bacteria,2G9CG@200795|Chloroflexi,374U7@32061|Chloroflexia	32061|Chloroflexia	G	LamG domain protein jellyroll fold domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_3,Laminin_G_3
CMS1_k127_2854228_2	326427.Cagg_3529	3.484e-35	143.0	COG0613@1|root,COG0613@2|Bacteria,2G74N@200795|Chloroflexi,37789@32061|Chloroflexia	32061|Chloroflexia	S	SMART phosphoesterase PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PHP,PHP_C
CMS1_k127_2854228_0	1242864.D187_004195	1.101e-90	305.0	COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,42SWD@68525|delta/epsilon subdivisions,2WK1W@28221|Deltaproteobacteria,2YYDA@29|Myxococcales	28221|Deltaproteobacteria	K	Sir2 family	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
CMS1_k127_2854228_3	926569.ANT_11560	4.682e-15	79.0	COG1269@1|root,COG1269@2|Bacteria	2|Bacteria	C	ATP hydrolysis coupled proton transport	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS1_k127_2862170_5	1035308.AQYY01000001_gene1810	7.24e-76	278.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	phoA	-	3.1.3.2	ko:K14379	ko00740,ko01100,ko04142,ko04380,ko05323,map00740,map01100,map04142,map04380,map05323	-	R00548	RC00017	ko00000,ko00001,ko01000	-	-	-	Metallophos
CMS1_k127_2862170_1	986075.CathTA2_1639	1.424e-175	573.0	COG2414@1|root,COG2414@2|Bacteria,1TPT9@1239|Firmicutes,4HFIP@91061|Bacilli	1239|Firmicutes	C	Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
CMS1_k127_2862170_12	671143.DAMO_2801	3.999e-05	49.0	COG1977@1|root,COG1977@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	ThiS,Ub-Mut7C
CMS1_k127_2862170_7	1121272.KB903249_gene2255	2.078e-43	164.0	COG0778@1|root,COG0778@2|Bacteria,2HG9I@201174|Actinobacteria,4DK68@85008|Micromonosporales	201174|Actinobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CMS1_k127_2862170_6	264198.Reut_B5782	8.262e-62	222.0	COG3618@1|root,COG3618@2|Bacteria,1NWR7@1224|Proteobacteria,2WC89@28216|Betaproteobacteria,1K7C2@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CMS1_k127_2862170_4	525904.Tter_1328	1.12e-103	347.0	COG0111@1|root,COG0111@2|Bacteria	2|Bacteria	EH	4-phosphoerythronate dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
CMS1_k127_2862170_2	926569.ANT_25080	1.188e-152	488.0	COG0667@1|root,COG0667@2|Bacteria,2G6BF@200795|Chloroflexi	200795|Chloroflexi	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS1_k127_2862170_0	479434.Sthe_3181	9.674e-226	722.0	COG1529@1|root,COG1529@2|Bacteria,2G65D@200795|Chloroflexi,27Y2Q@189775|Thermomicrobia	189775|Thermomicrobia	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
CMS1_k127_2862170_11	309801.trd_0321	2.553e-09	63.0	COG1942@1|root,COG1942@2|Bacteria,2GB2N@200795|Chloroflexi,27ZBJ@189775|Thermomicrobia	189775|Thermomicrobia	S	4-Oxalocrotonate Tautomerase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2862170_10	357808.RoseRS_2575	1.832e-15	81.0	COG1942@1|root,COG1942@2|Bacteria,2G9KE@200795|Chloroflexi,377TH@32061|Chloroflexia	32061|Chloroflexia	S	TIGRFAM 4-oxalocrotonate tautomerase family enzyme	-	-	5.3.2.6	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R03966,R05389	RC01040,RC01355	ko00000,ko00001,ko00002,ko01000	-	-	-	Tautomerase
CMS1_k127_2862170_8	743525.TSC_c11540	2.382e-41	158.0	COG0599@1|root,COG0599@2|Bacteria,1WK2N@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS1_k127_2862170_3	644966.Tmar_1792	9.516e-148	473.0	COG0346@1|root,COG0346@2|Bacteria,1U664@1239|Firmicutes	1239|Firmicutes	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	1.13.11.2	ko:K00446	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
CMS1_k127_2862170_9	1123024.AUII01000001_gene3090	1.262e-34	141.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria,4EAZC@85010|Pseudonocardiales	201174|Actinobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
CMS1_k127_2864679_7	429009.Adeg_0477	2.568e-12	80.0	COG0860@1|root,COG3103@1|root,COG0860@2|Bacteria,COG4991@2|Bacteria,1UYPW@1239|Firmicutes,24BHU@186801|Clostridia,42F03@68295|Thermoanaerobacterales	186801|Clostridia	M	PFAM cell wall hydrolase autolysin	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3,Cu_amine_oxidN1,SH3_3,SLT
CMS1_k127_2864679_6	935948.KE386494_gene713	5.69e-32	144.0	COG1470@1|root,COG1470@2|Bacteria,1TRGE@1239|Firmicutes,24EHG@186801|Clostridia,42GPK@68295|Thermoanaerobacterales	186801|Clostridia	S	Protein of unknown function (DUF3048) C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3048,DUF3048_C
CMS1_k127_2864679_2	1122164.JHWF01000002_gene784	1.996e-89	305.0	COG0429@1|root,COG0429@2|Bacteria,1MWV1@1224|Proteobacteria,1SXYI@1236|Gammaproteobacteria,1JD47@118969|Legionellales	118969|Legionellales	S	Serine aminopeptidase, S33	-	-	-	ko:K07019	-	-	-	-	ko00000	-	-	-	Hydrolase_4
CMS1_k127_2864679_1	1173028.ANKO01000244_gene3949	4.82e-125	404.0	COG0384@1|root,COG0384@2|Bacteria,1G2GP@1117|Cyanobacteria,1HHDU@1150|Oscillatoriales	1117|Cyanobacteria	S	Phenazine biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
CMS1_k127_2864679_4	498761.HM1_1035	1.778e-51	186.0	COG0350@1|root,COG0350@2|Bacteria,1VA03@1239|Firmicutes,24JAA@186801|Clostridia	186801|Clostridia	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
CMS1_k127_2864679_0	326427.Cagg_1543	5.773e-158	503.0	COG0451@1|root,COG0451@2|Bacteria,2GBWQ@200795|Chloroflexi,3774S@32061|Chloroflexia	32061|Chloroflexia	M	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
CMS1_k127_2864679_3	401053.AciPR4_4273	8.459e-87	306.0	COG2244@1|root,COG2244@2|Bacteria,3Y7TW@57723|Acidobacteria,2JN3I@204432|Acidobacteriia	204432|Acidobacteriia	S	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_C
CMS1_k127_2864679_5	756067.MicvaDRAFT_5390	1.703e-43	160.0	COG0438@1|root,COG0438@2|Bacteria,1FZUY@1117|Cyanobacteria,1H72J@1150|Oscillatoriales	1117|Cyanobacteria	M	glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2,Glyco_trans_1_4,Glyco_transf_4,Glyco_transf_41,Glycos_transf_1,Glycos_transf_2,Methyltransf_11,Methyltransf_21,Methyltransf_23
CMS1_k127_2866442_9	326427.Cagg_3758	2.155e-33	141.0	COG3266@1|root,COG3266@2|Bacteria,2G9F4@200795|Chloroflexi,377QC@32061|Chloroflexia	32061|Chloroflexia	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2866442_6	326427.Cagg_3759	1.975e-48	179.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS1_k127_2866442_0	926550.CLDAP_36010	7.476e-181	598.0	COG3103@1|root,COG3103@2|Bacteria	2|Bacteria	T	Sh3 type 3 domain protein	-	-	3.5.1.28	ko:K01448,ko:K07448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko02048,ko03036	-	-	-	Muraidase,SH3_3,SLH
CMS1_k127_2866442_2	765420.OSCT_3186	3.918e-84	305.0	COG4995@1|root,COG4995@2|Bacteria,2G8YF@200795|Chloroflexi,377C0@32061|Chloroflexia	32061|Chloroflexia	P	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,SIR2_2
CMS1_k127_2866442_3	247490.KSU1_B0602	2.852e-78	295.0	COG1672@1|root,COG3064@1|root,COG1672@2|Bacteria,COG3064@2|Bacteria,2IXC3@203682|Planctomycetes	203682|Planctomycetes	M	PFAM Archaeal ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,WD40
CMS1_k127_2866442_8	357808.RoseRS_1915	4.89e-40	172.0	COG0823@1|root,COG0823@2|Bacteria,2G8PZ@200795|Chloroflexi,377MH@32061|Chloroflexia	32061|Chloroflexia	U	WD40 domain protein beta Propeller	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
CMS1_k127_2866442_1	251229.Chro_5489	1.484e-91	308.0	COG2816@1|root,COG2816@2|Bacteria,1G3EM@1117|Cyanobacteria	1117|Cyanobacteria	L	Belongs to the Nudix hydrolase family. NudC subfamily	nudC	-	3.6.1.22	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	-	R00103,R03004,R11104	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX,NUDIX-like,zf-NADH-PPase
CMS1_k127_2866442_5	861299.J421_0777	3.227e-54	193.0	COG2258@1|root,COG2258@2|Bacteria	2|Bacteria	C	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
CMS1_k127_2866442_4	926550.CLDAP_10290	5.392e-55	198.0	COG1853@1|root,COG1853@2|Bacteria,2G6XG@200795|Chloroflexi	200795|Chloroflexi	S	PFAM flavin reductase domain protein, FMN-binding	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
CMS1_k127_2866442_7	316274.Haur_3451	2.021e-44	167.0	COG2761@1|root,COG2761@2|Bacteria,2G7EP@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM DSBA oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
CMS1_k127_2866442_10	28444.JODQ01000005_gene1475	1.499e-15	90.0	COG1361@1|root,COG4625@1|root,COG4719@1|root,COG1361@2|Bacteria,COG4625@2|Bacteria,COG4719@2|Bacteria,2I8F1@201174|Actinobacteria,4EKYK@85012|Streptosporangiales	201174|Actinobacteria	M	Putative Ig domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,He_PIG,fn3
CMS1_k127_2872746_4	697281.Mahau_2243	0.0005621	42.0	COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,42EQM@68295|Thermoanaerobacterales	186801|Clostridia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
CMS1_k127_2872746_2	105559.Nwat_0947	2.038e-23	112.0	2C6D0@1|root,31F07@2|Bacteria,1RHBN@1224|Proteobacteria,1S7HH@1236|Gammaproteobacteria,1WX2B@135613|Chromatiales	135613|Chromatiales	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
CMS1_k127_2872746_0	1249627.D779_3748	1.499e-263	842.0	COG1277@1|root,COG3225@1|root,COG1277@2|Bacteria,COG3225@2|Bacteria,1NZZ9@1224|Proteobacteria,1RP6C@1236|Gammaproteobacteria,1WX0W@135613|Chromatiales	135613|Chromatiales	N	transport system	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
CMS1_k127_2872746_1	502025.Hoch_5380	8.945e-104	345.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42NF6@68525|delta/epsilon subdivisions,2WKVH@28221|Deltaproteobacteria,2YUUC@29|Myxococcales	28221|Deltaproteobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_2872746_3	926550.CLDAP_12350	2.162e-11	73.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	3.4.21.107,3.5.1.28	ko:K01448,ko:K04771	ko01503,ko02020,map01503,map02020	M00727,M00728	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko03036,ko03110	-	-	-	SH3_3
CMS1_k127_287571_7	383372.Rcas_2842	2.668e-08	66.0	2BQM9@1|root,2ZH6F@2|Bacteria	2|Bacteria	S	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
CMS1_k127_287571_6	405948.SACE_7351	2.219e-15	83.0	COG0360@1|root,COG0360@2|Bacteria,2IQHD@201174|Actinobacteria,4E4WX@85010|Pseudonocardiales	201174|Actinobacteria	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0019843,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071944,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
CMS1_k127_287571_4	926569.ANT_22420	2.083e-43	162.0	COG0629@1|root,COG0629@2|Bacteria,2G6YE@200795|Chloroflexi	200795|Chloroflexi	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
CMS1_k127_287571_5	525904.Tter_0780	9.243e-24	104.0	COG0238@1|root,COG0238@2|Bacteria,2NQ53@2323|unclassified Bacteria	2|Bacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963,ko:K03111,ko:K15125	ko03010,ko03030,ko03430,ko03440,ko05133,map03010,map03030,map03430,map03440,map05133	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko00536,ko03011,ko03029,ko03032,ko03400	-	-	-	Ribosomal_S18
CMS1_k127_287571_3	926550.CLDAP_17430	1.454e-46	184.0	COG0760@1|root,COG0760@2|Bacteria,2G6RV@200795|Chloroflexi	200795|Chloroflexi	O	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase,Rotamase_3,SurA_N_3
CMS1_k127_287571_0	926569.ANT_04650	3.297e-230	726.0	COG0031@1|root,COG0031@2|Bacteria,2G8GE@200795|Chloroflexi	200795|Chloroflexi	E	Pyridoxal-phosphate dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	PALP
CMS1_k127_287571_1	926569.ANT_04660	4.603e-124	405.0	COG0463@1|root,COG0463@2|Bacteria,2G5JH@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
CMS1_k127_287571_2	525904.Tter_0018	1.229e-82	285.0	COG1940@1|root,COG1940@2|Bacteria,2NPRP@2323|unclassified Bacteria	2|Bacteria	GK	ROK family	glcK	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10220	ROK
CMS1_k127_287571_8	1382306.JNIM01000001_gene971	0.0003551	50.0	COG1305@1|root,COG1305@2|Bacteria,2G66M@200795|Chloroflexi	200795|Chloroflexi	E	PFAM transglutaminase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129,Transglut_core
CMS1_k127_2883071_0	1173023.KE650771_gene5588	2.099e-226	735.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria	1117|Cyanobacteria	Q	Amino acid adenylation domain	-	-	5.1.1.13	ko:K01779	ko00250,ko01054,map00250,map01054	-	R00491	RC00302	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C,Bac_luciferase,Condensation,PP-binding,Thioesterase
CMS1_k127_2883071_2	880073.Calab_0600	3.141e-06	53.0	COG0472@1|root,COG2148@1|root,COG0472@2|Bacteria,COG2148@2|Bacteria,2NPJ8@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferase family 4	tagO	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0034645,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0045229,GO:0046872,GO:0046914,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:1901576	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
CMS1_k127_2883071_1	356851.JOAN01000002_gene845	1.565e-33	136.0	COG0537@1|root,COG0537@2|Bacteria,2IMBA@201174|Actinobacteria,4DEFU@85008|Micromonosporales	201174|Actinobacteria	FG	HIT domain	-	-	-	-	-	-	-	-	-	-	-	-	HIT
CMS1_k127_2889390_2	42256.RradSPS_0297	3.295e-10	63.0	COG3635@1|root,COG3635@2|Bacteria,2IQCA@201174|Actinobacteria	201174|Actinobacteria	G	2,3-bisphosphoglycerate-independent phosphoglycerate mutase	-	-	5.4.2.12	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,PhosphMutase
CMS1_k127_2889390_0	926550.CLDAP_22740	2.823e-161	515.0	COG3842@1|root,COG3842@2|Bacteria,2G5X9@200795|Chloroflexi	200795|Chloroflexi	P	PFAM ABC transporter related	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
CMS1_k127_2889390_1	926550.CLDAP_37910	2.712e-64	233.0	COG1609@1|root,COG1609@2|Bacteria	2|Bacteria	K	purine nucleotide biosynthetic process	aglR	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
CMS1_k127_28916_2	1348338.ADILRU_1521	1.318e-123	415.0	COG0747@1|root,COG0747@2|Bacteria,2GMAX@201174|Actinobacteria,4FMQ0@85023|Microbacteriaceae	201174|Actinobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_28916_4	1487923.DP73_09870	2.094e-120	395.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,263XS@186807|Peptococcaceae	186801|Clostridia	U	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_28916_7	1487923.DP73_09875	8.536e-98	328.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia	186801|Clostridia	P	ABC-type dipeptide oligopeptide nickel transport	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
CMS1_k127_28916_11	1348338.ADILRU_1514	2.691e-67	244.0	COG0006@1|root,COG0006@2|Bacteria,2GM7D@201174|Actinobacteria,4FMV3@85023|Microbacteriaceae	201174|Actinobacteria	E	Creatinase/Prolidase N-terminal domain	pepE	-	3.4.13.9	ko:K01271,ko:K01274	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
CMS1_k127_28916_1	1380390.JIAT01000001_gene5136	7.249e-154	498.0	COG4284@1|root,COG4284@2|Bacteria,2I2G3@201174|Actinobacteria,4CR16@84995|Rubrobacteria	84995|Rubrobacteria	G	UTP--glucose-1-phosphate uridylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	UDPGP
CMS1_k127_28916_9	926550.CLDAP_16290	5.202e-85	291.0	COG2301@1|root,COG2301@2|Bacteria,2G6EA@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the HpcH HpaI aldolase family	-	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006107,GO:0008150,GO:0008152,GO:0009987,GO:0015977,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0043167,GO:0043169,GO:0043427,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0046872,GO:0047777,GO:0050083,GO:0071704	4.1.3.24,4.1.3.25,4.1.3.34	ko:K01644,ko:K08691	ko00630,ko00660,ko00680,ko00720,ko01120,ko01200,ko02020,map00630,map00660,map00680,map00720,map01120,map01200,map02020	M00346,M00373,M00376	R00237,R00362,R00473,R00934	RC00067,RC00307,RC00308,RC00311,RC00407,RC00502,RC01118,RC01205	ko00000,ko00001,ko00002,ko01000	-	-	-	HpcH_HpaI
CMS1_k127_28916_12	926550.CLDAP_16300	6.071e-64	223.0	COG2030@1|root,COG2030@2|Bacteria,2G6YG@200795|Chloroflexi	200795|Chloroflexi	I	PFAM MaoC domain protein dehydratase	-	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009436,GO:0009987,GO:0015977,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043427,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0046395,GO:0046487,GO:0071704,GO:0072329,GO:1901575	4.2.1.148	ko:K14449	ko00630,ko00660,ko00720,ko01120,ko01200,map00630,map00660,map00720,map01120,map01200	M00373,M00376,M00740	R05076	RC01984	ko00000,ko00001,ko00002,ko01000	-	-	-	MaoC_dehydratas
CMS1_k127_28916_13	926569.ANT_15050	2.595e-59	215.0	COG0805@1|root,COG0805@2|Bacteria,2G6SP@200795|Chloroflexi	200795|Chloroflexi	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
CMS1_k127_28916_22	195253.Syn6312_1879	5.266e-05	55.0	COG1826@1|root,COG1826@2|Bacteria,1G7W1@1117|Cyanobacteria,1H118@1129|Synechococcus	1117|Cyanobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
CMS1_k127_28916_16	926569.ANT_14610	7.367e-36	141.0	COG0781@1|root,COG0781@2|Bacteria,2G6XA@200795|Chloroflexi	200795|Chloroflexi	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
CMS1_k127_28916_8	926550.CLDAP_15710	4.338e-89	301.0	COG1028@1|root,COG1028@2|Bacteria,2G5KB@200795|Chloroflexi	200795|Chloroflexi	IQ	PFAM short-chain dehydrogenase reductase SDR	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS1_k127_28916_10	1280674.AUJK01000002_gene1374	7.185e-85	291.0	COG0331@1|root,COG0331@2|Bacteria,4NE1D@976|Bacteroidetes,2FM9P@200643|Bacteroidia	976|Bacteroidetes	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
CMS1_k127_28916_21	485913.Krac_8243	3.59e-13	71.0	COG0333@1|root,COG0333@2|Bacteria,2G7EA@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
CMS1_k127_28916_18	357808.RoseRS_2612	1.058e-24	111.0	COG1399@1|root,COG1399@2|Bacteria,2G6Z5@200795|Chloroflexi,375SZ@32061|Chloroflexia	32061|Chloroflexia	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
CMS1_k127_28916_17	926569.ANT_15290	3.94e-29	123.0	COG0711@1|root,COG0711@2|Bacteria,2G79J@200795|Chloroflexi	200795|Chloroflexi	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_28916_14	1128421.JAGA01000002_gene1724	1.19e-53	193.0	COG0669@1|root,COG0669@2|Bacteria,2NPDV@2323|unclassified Bacteria	2|Bacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	GO:0003674,GO:0003824,GO:0004595,GO:0005488,GO:0005515,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0015939,GO:0015940,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046390,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iPC815.YPO0053,iSDY_1059.SDY_4064	CTP_transf_like
CMS1_k127_28916_0	479434.Sthe_1906	5.193e-223	717.0	COG1200@1|root,COG1200@2|Bacteria,2G5YM@200795|Chloroflexi,27XT4@189775|Thermomicrobia	189775|Thermomicrobia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
CMS1_k127_28916_15	316274.Haur_0364	1.011e-51	193.0	COG1307@1|root,COG1307@2|Bacteria,2G6P2@200795|Chloroflexi,374VJ@32061|Chloroflexia	32061|Chloroflexia	S	PFAM DegV family protein	-	-	-	-	-	-	-	-	-	-	-	-	DegV
CMS1_k127_28916_3	1382306.JNIM01000001_gene214	6.824e-122	409.0	COG1461@1|root,COG1461@2|Bacteria,2G61Z@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Dak phosphatase	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
CMS1_k127_28916_5	926550.CLDAP_30420	3.798e-108	377.0	COG5305@1|root,COG5305@2|Bacteria,2G7EE@200795|Chloroflexi	2|Bacteria	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2142,PMT_2
CMS1_k127_28916_19	926550.CLDAP_35680	8.995e-24	112.0	COG1989@1|root,COG1989@2|Bacteria	2|Bacteria	NOU	aspartic-type endopeptidase activity	pppA	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
CMS1_k127_28916_20	225937.HP15_1557	4.255e-22	102.0	COG1254@1|root,COG1254@2|Bacteria,1N6NU@1224|Proteobacteria,1SCPF@1236|Gammaproteobacteria,468VX@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	acylphosphatase activity	acyP	GO:0003674,GO:0003824,GO:0003998,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016787,GO:0016817,GO:0016818,GO:0050896	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	iSBO_1134.SBO_2263,iSF_1195.SF0969,iSFxv_1172.SFxv_1053,iS_1188.S1036	Acylphosphatase
CMS1_k127_28916_6	1463934.JOCF01000055_gene2016	8.694e-105	366.0	COG0542@1|root,COG0542@2|Bacteria,2GJ73@201174|Actinobacteria	201174|Actinobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
CMS1_k127_2892728_3	1035189.HMPREF9954_0972	1.006e-14	76.0	COG0266@1|root,COG0266@2|Bacteria,1TPM9@1239|Firmicutes,4H9Q7@91061|Bacilli,43FJJ@68892|Streptococcus infantis	91061|Bacilli	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
CMS1_k127_2892728_1	525904.Tter_1414	1.676e-35	143.0	COG2802@1|root,COG2802@2|Bacteria,2NPRK@2323|unclassified Bacteria	2|Bacteria	S	ATP-dependent protease La (LON) substrate-binding domain	lonD	-	3.4.21.53	ko:K01338,ko:K07157	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	LON_substr_bdg
CMS1_k127_2892728_0	526225.Gobs_2142	2.942e-68	259.0	COG3391@1|root,COG4995@1|root,COG3391@2|Bacteria,COG4995@2|Bacteria,2HF98@201174|Actinobacteria,4EWDJ@85013|Frankiales	201174|Actinobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2892728_4	32057.KB217483_gene9923	1.995e-11	68.0	COG0457@1|root,COG0457@2|Bacteria,1G7YQ@1117|Cyanobacteria	1117|Cyanobacteria	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_8
CMS1_k127_2892728_2	1121403.AUCV01000009_gene1468	3.592e-20	93.0	COG2074@1|root,COG2074@2|Bacteria,1NUN9@1224|Proteobacteria	1224|Proteobacteria	G	phosphotransferase activity, carboxyl group as acceptor	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_289500_0	926550.CLDAP_39920	2.149e-89	305.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	DUF1929,F5_F8_type_C,Glyco_hyd_65N_2,Glyco_hydro_18,He_PIG,PA14,RCC1,SLH
CMS1_k127_289500_1	1173029.JH980292_gene614	4.056e-27	128.0	COG3187@1|root,COG3187@2|Bacteria	2|Bacteria	O	response to heat	-	-	-	ko:K03668,ko:K09914	-	-	-	-	ko00000	-	-	-	META,YscW
CMS1_k127_289500_2	635013.TherJR_2659	2.675e-26	119.0	COG2120@1|root,COG2120@2|Bacteria,1TQM2@1239|Firmicutes,24EYU@186801|Clostridia,262YI@186807|Peptococcaceae	186801|Clostridia	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,PIG-L
CMS1_k127_289500_3	981369.JQMJ01000004_gene457	1.162e-13	82.0	COG0392@1|root,COG0392@2|Bacteria,2HQM0@201174|Actinobacteria,2NM75@228398|Streptacidiphilus	201174|Actinobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
CMS1_k127_289500_4	84531.JMTZ01000009_gene3296	3.991e-10	69.0	COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,1RMV7@1236|Gammaproteobacteria,1X4AM@135614|Xanthomonadales	135614|Xanthomonadales	H	O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway	ubiG	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23
CMS1_k127_2903080_21	925409.KI911562_gene1751	5.409e-16	87.0	COG1479@1|root,COG1479@2|Bacteria	2|Bacteria	U	Protein of unknown function DUF262	yfjM	-	-	-	-	-	-	-	-	-	-	-	DUF1524,DUF262
CMS1_k127_2903080_0	331678.Cphamn1_1675	0.0	1042.0	COG4930@1|root,COG4930@2|Bacteria	2|Bacteria	O	Putative ATP-dependent Lon protease	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Lon_2,MIT_C
CMS1_k127_2903080_16	1121935.AQXX01000127_gene1130	1.656e-40	153.0	COG4319@1|root,COG4319@2|Bacteria,1N8AM@1224|Proteobacteria	1224|Proteobacteria	S	ketosteroid isomerase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
CMS1_k127_2903080_13	1313304.CALK_1985	9.221e-51	198.0	COG1228@1|root,COG1228@2|Bacteria	2|Bacteria	Q	imidazolonepropionase activity	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
CMS1_k127_2903080_20	696281.Desru_0606	1.299e-20	99.0	COG1309@1|root,COG1309@2|Bacteria,1UYPJ@1239|Firmicutes,24E8U@186801|Clostridia,2674P@186807|Peptococcaceae	186801|Clostridia	K	QacR-like protein, C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_5,TetR_N
CMS1_k127_2903080_11	338966.Ppro_2906	2.424e-55	208.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,42P7V@68525|delta/epsilon subdivisions,2WJQA@28221|Deltaproteobacteria,43TTY@69541|Desulfuromonadales	28221|Deltaproteobacteria	V	ABC-2 family transporter protein	ybhS	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
CMS1_k127_2903080_8	243231.GSU2826	8.915e-56	209.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,42NC3@68525|delta/epsilon subdivisions,2WIJJ@28221|Deltaproteobacteria,43T8A@69541|Desulfuromonadales	28221|Deltaproteobacteria	V	ABC-2 family transporter protein	ybhR	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
CMS1_k127_2903080_14	405948.SACE_4048	1.47e-48	179.0	COG0748@1|root,COG0748@2|Bacteria,2IIRT@201174|Actinobacteria,4E4KM@85010|Pseudonocardiales	201174|Actinobacteria	P	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
CMS1_k127_2903080_19	316274.Haur_1965	4.438e-30	127.0	COG1309@1|root,COG1309@2|Bacteria,2G8V2@200795|Chloroflexi	200795|Chloroflexi	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS1_k127_2903080_2	765420.OSCT_0044	3.48e-114	379.0	COG0842@1|root,COG0842@2|Bacteria,2G6PG@200795|Chloroflexi,37723@32061|Chloroflexia	32061|Chloroflexia	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
CMS1_k127_2903080_12	1123368.AUIS01000024_gene949	3.013e-53	201.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,1RPB4@1236|Gammaproteobacteria,2NBU9@225057|Acidithiobacillales	225057|Acidithiobacillales	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
CMS1_k127_2903080_6	935948.KE386494_gene124	1.274e-56	212.0	COG0842@1|root,COG0842@2|Bacteria,1TQG7@1239|Firmicutes,249TT@186801|Clostridia,42ETY@68295|Thermoanaerobacterales	186801|Clostridia	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
CMS1_k127_2903080_4	243231.GSU3608	1.772e-93	317.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42PIB@68525|delta/epsilon subdivisions,2WKFC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	ABC transporter	ybhF-N	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
CMS1_k127_2903080_3	264732.Moth_1900	9.532e-107	355.0	COG1131@1|root,COG1131@2|Bacteria,1TQKM@1239|Firmicutes,25B35@186801|Clostridia,42FFN@68295|Thermoanaerobacterales	186801|Clostridia	V	pfam abc	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_2903080_5	357808.RoseRS_2104	4.957e-62	231.0	COG0845@1|root,COG1566@1|root,COG0845@2|Bacteria,COG1566@2|Bacteria,2G93B@200795|Chloroflexi,3764W@32061|Chloroflexia	32061|Chloroflexia	MV	PFAM secretion protein HlyD family protein	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23
CMS1_k127_2903080_10	765420.OSCT_0043	2.318e-55	210.0	COG0845@1|root,COG1566@1|root,COG0845@2|Bacteria,COG1566@2|Bacteria,2G93B@200795|Chloroflexi,3764W@32061|Chloroflexia	32061|Chloroflexia	MV	PFAM secretion protein HlyD family protein	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23
CMS1_k127_2903080_7	756272.Plabr_0415	3.737e-56	206.0	28XGS@1|root,2ZJE7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2903080_15	324602.Caur_3225	1.391e-45	169.0	COG1669@1|root,COG1669@2|Bacteria,2G9Y2@200795|Chloroflexi,377UA@32061|Chloroflexia	32061|Chloroflexia	L	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
CMS1_k127_2903080_22	1521187.JPIM01000048_gene76	8.17e-06	51.0	COG2250@1|root,COG2250@2|Bacteria	2|Bacteria	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
CMS1_k127_2903080_18	1521187.JPIM01000021_gene140	2.796e-30	121.0	COG2250@1|root,COG2250@2|Bacteria	2|Bacteria	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
CMS1_k127_2903080_1	926550.CLDAP_33840	3.041e-133	434.0	COG1313@1|root,COG1313@2|Bacteria,2G65I@200795|Chloroflexi	200795|Chloroflexi	C	Radical SAM domain protein	-	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
CMS1_k127_2903080_9	926569.ANT_29450	1.316e-55	206.0	COG0583@1|root,COG0583@2|Bacteria,2G70X@200795|Chloroflexi	200795|Chloroflexi	K	regulatory protein LysR	-	-	-	ko:K21703	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
CMS1_k127_2903080_17	880073.Calab_1605	9.017e-37	145.0	COG2897@1|root,COG2897@2|Bacteria	2|Bacteria	P	thiosulfate sulfurtransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CMS1_k127_2913586_3	1166948.JPZL01000004_gene50	1.285e-51	193.0	COG4585@1|root,COG5002@1|root,COG4585@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HWE_HK,HisKA_3,PAS_4
CMS1_k127_2913586_6	518766.Rmar_2227	1.401e-25	111.0	COG2197@1|root,COG2197@2|Bacteria,4NP2G@976|Bacteroidetes,1FIR1@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS1_k127_2913586_4	323261.Noc_0461	2.663e-30	121.0	COG4572@1|root,COG4572@2|Bacteria,1N93H@1224|Proteobacteria,1S94E@1236|Gammaproteobacteria,1X1ZU@135613|Chromatiales	135613|Chromatiales	S	ChaB	-	-	-	ko:K06197	-	-	-	-	ko00000	-	-	-	ChaB
CMS1_k127_2913586_7	1267005.KB911263_gene1334	4.876e-05	49.0	COG5607@1|root,COG5607@2|Bacteria,1RH6R@1224|Proteobacteria,2U7IN@28211|Alphaproteobacteria,3N7G4@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	CHAD	-	-	-	-	-	-	-	-	-	-	-	-	CHAD
CMS1_k127_2913586_0	697282.Mettu_0616	2.753e-159	511.0	COG0446@1|root,COG0446@2|Bacteria,1NR3M@1224|Proteobacteria,1RN6P@1236|Gammaproteobacteria,1XEW5@135618|Methylococcales	135618|Methylococcales	C	Apoptosis-inducing factor, mitochondrion-associated, C-term	-	-	-	-	-	-	-	-	-	-	-	-	AIF_C,Pyr_redox_2
CMS1_k127_2913586_1	429009.Adeg_1032	1.081e-79	280.0	COG0438@1|root,COG0438@2|Bacteria,1TPTA@1239|Firmicutes,24ANI@186801|Clostridia,42FW0@68295|Thermoanaerobacterales	186801|Clostridia	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS1_k127_2913586_2	479434.Sthe_0126	1.516e-66	237.0	COG2515@1|root,COG2515@2|Bacteria,2G6PX@200795|Chloroflexi,27YZ5@189775|Thermomicrobia	189775|Thermomicrobia	E	Pyridoxal-phosphate dependent enzyme	-	-	4.4.1.15	ko:K05396	ko00270,map00270	-	R01874	RC00382	ko00000,ko00001,ko01000	-	-	-	PALP
CMS1_k127_2918755_8	926550.CLDAP_39790	4.982e-51	183.0	COG1164@1|root,COG1164@2|Bacteria,2G5JB@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M3A and M3B, thimet oligopeptidase F	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
CMS1_k127_2918755_1	204669.Acid345_3108	1.637e-229	724.0	COG0028@1|root,COG0028@2|Bacteria,3Y3GJ@57723|Acidobacteria,2JI90@204432|Acidobacteriia	204432|Acidobacteriia	EH	Acetolactate synthase, large subunit	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS1_k127_2918755_7	926569.ANT_03270	1.656e-52	190.0	COG0440@1|root,COG0440@2|Bacteria,2G6NW@200795|Chloroflexi	200795|Chloroflexi	E	Acetolactate synthase, small subunit	ilvN	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_5,ALS_ss_C
CMS1_k127_2918755_4	316274.Haur_4447	3.484e-147	472.0	COG0059@1|root,COG0059@2|Bacteria,2G5NP@200795|Chloroflexi,3758Y@32061|Chloroflexia	32061|Chloroflexia	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
CMS1_k127_2918755_2	65071.PYU1_T007100	3.407e-226	714.0	COG0119@1|root,KOG2367@2759|Eukaryota,1ME2M@121069|Pythiales	121069|Pythiales	E	2-isopropylmalate synthase. Source PGD	-	-	-	-	-	-	-	-	-	-	-	-	HMGL-like,LeuA_dimer
CMS1_k127_2918755_3	1267535.KB906767_gene3365	2.195e-225	708.0	COG0065@1|root,COG0065@2|Bacteria,3Y2ID@57723|Acidobacteria,2JI0J@204432|Acidobacteriia	204432|Acidobacteriia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
CMS1_k127_2918755_6	1128421.JAGA01000002_gene1557	4.982e-81	275.0	COG0066@1|root,COG0066@2|Bacteria,2NRA0@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
CMS1_k127_2918755_0	395494.Galf_0349	1.62e-230	726.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,2VI4G@28216|Betaproteobacteria,44V3P@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Belongs to the alpha-IPM synthase homocitrate synthase family	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
CMS1_k127_2918755_9	316274.Haur_3849	7.087e-45	187.0	COG4485@1|root,COG4485@2|Bacteria,2G75F@200795|Chloroflexi,3771H@32061|Chloroflexia	32061|Chloroflexia	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
CMS1_k127_2918755_5	1128421.JAGA01000002_gene1556	1.577e-139	452.0	COG0473@1|root,COG0473@2|Bacteria,2NP1R@2323|unclassified Bacteria	2|Bacteria	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
CMS1_k127_2918755_10	1122921.KB898209_gene2653	5.401e-05	46.0	2BR0X@1|root,32JYC@2|Bacteria,1U1R4@1239|Firmicutes,4IB7I@91061|Bacilli,273UA@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2927425_2	926569.ANT_09930	1.005e-96	334.0	COG1300@1|root,COG1668@1|root,COG1300@2|Bacteria,COG1668@2|Bacteria,2G8CN@200795|Chloroflexi	200795|Chloroflexi	CP	Stage II sporulation protein M	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC2_membrane_2,SpoIIM
CMS1_k127_2927425_0	765420.OSCT_0605	1.476e-106	354.0	COG1131@1|root,COG1131@2|Bacteria,2G890@200795|Chloroflexi,374U5@32061|Chloroflexia	32061|Chloroflexia	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_2927425_3	102232.GLO73106DRAFT_00020080	5.568e-61	220.0	COG3597@1|root,COG3597@2|Bacteria,1G0MM@1117|Cyanobacteria	1117|Cyanobacteria	S	Short C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF697,SHOCT
CMS1_k127_2927425_4	243233.MCA3064	5.84e-10	70.0	2EQEC@1|root,33I0C@2|Bacteria,1NP5N@1224|Proteobacteria,1SGGK@1236|Gammaproteobacteria,1XGVA@135618|Methylococcales	135618|Methylococcales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2927425_1	102125.Xen7305DRAFT_00051820	2.337e-106	380.0	COG2911@1|root,COG2931@1|root,COG2911@2|Bacteria,COG2931@2|Bacteria,1G625@1117|Cyanobacteria	1117|Cyanobacteria	Q	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
CMS1_k127_2934164_23	525904.Tter_1021	6.905e-17	91.0	COG3745@1|root,COG3745@2|Bacteria,2NRT1@2323|unclassified Bacteria	2|Bacteria	U	Flp pilus assembly protein RcpC/CpaB	cpaB	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	ChapFlgA,RcpC,SAF
CMS1_k127_2934164_18	1128421.JAGA01000002_gene595	3.387e-46	184.0	COG4753@1|root,COG4963@1|root,COG4753@2|Bacteria,COG4963@2|Bacteria,2NR3E@2323|unclassified Bacteria	2|Bacteria	D	AAA domain	flpE	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,CbiA,ParA,Response_reg
CMS1_k127_2934164_15	1382356.JQMP01000003_gene2237	1.011e-60	221.0	COG4965@1|root,COG4965@2|Bacteria,2G6GS@200795|Chloroflexi,27XX2@189775|Thermomicrobia	189775|Thermomicrobia	U	Type II secretion system (T2SS), protein F	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
CMS1_k127_2934164_14	479434.Sthe_0521	1.081e-62	226.0	COG2064@1|root,COG2064@2|Bacteria,2G6CF@200795|Chloroflexi,27XSY@189775|Thermomicrobia	189775|Thermomicrobia	NU	Type II secretion system (T2SS), protein F	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
CMS1_k127_2934164_20	926550.CLDAP_35720	2.618e-29	132.0	COG0457@1|root,COG0823@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
CMS1_k127_2934164_19	926550.CLDAP_35720	4.413e-34	149.0	COG0457@1|root,COG0823@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
CMS1_k127_2934164_22	1379698.RBG1_1C00001G0991	3.178e-19	104.0	COG2911@1|root,COG2931@1|root,COG4447@1|root,COG2911@2|Bacteria,COG2931@2|Bacteria,COG4447@2|Bacteria,2NR5X@2323|unclassified Bacteria	2|Bacteria	Q	FlgD Ig-like domain	-	-	3.2.1.136	ko:K15924	-	-	-	-	ko00000,ko01000	-	GH5	-	CBM_3,DUF1735,Laminin_G_3
CMS1_k127_2934164_24	357808.RoseRS_1003	3.493e-15	86.0	COG3764@1|root,COG3764@2|Bacteria,2G98S@200795|Chloroflexi,375IR@32061|Chloroflexia	32061|Chloroflexia	M	PFAM peptidase C60, sortase A and B	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
CMS1_k127_2934164_12	926550.CLDAP_26540	9.197e-76	261.0	COG1136@1|root,COG1136@2|Bacteria,2G6FP@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_2934164_8	383372.Rcas_4355	5.708e-114	377.0	COG1136@1|root,COG1136@2|Bacteria,2G5S3@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
CMS1_k127_2934164_0	926550.CLDAP_26560	1.251e-319	1006.0	COG0577@1|root,COG0577@2|Bacteria,2G5WX@200795|Chloroflexi	200795|Chloroflexi	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
CMS1_k127_2934164_11	926550.CLDAP_26570	4.324e-95	330.0	COG0845@1|root,COG0845@2|Bacteria,2G8Q8@200795|Chloroflexi	200795|Chloroflexi	M	secretion protein HlyD family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
CMS1_k127_2934164_21	357808.RoseRS_4160	6.89e-26	120.0	COG3852@1|root,COG3852@2|Bacteria,2GAKC@200795|Chloroflexi,3775A@32061|Chloroflexia	32061|Chloroflexia	T	PFAM ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4
CMS1_k127_2934164_17	383372.Rcas_2795	1.517e-51	192.0	COG0745@1|root,COG0745@2|Bacteria,2G8W7@200795|Chloroflexi,375AC@32061|Chloroflexia	32061|Chloroflexia	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_2934164_13	1267535.KB906767_gene2354	2.074e-70	250.0	COG1609@1|root,COG1609@2|Bacteria,3Y6K5@57723|Acidobacteria	57723|Acidobacteria	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K05499	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
CMS1_k127_2934164_1	266117.Rxyl_2071	3.881e-182	581.0	COG2182@1|root,COG2182@2|Bacteria	2|Bacteria	G	maltose binding	-	-	-	ko:K17237	ko02010,map02010	M00599	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.38	-	iLJ478.TM0418	SBP_bac_1,SBP_bac_8
CMS1_k127_2934164_6	266117.Rxyl_2070	9.548e-125	407.0	COG1175@1|root,COG1175@2|Bacteria,2GJGB@201174|Actinobacteria	201174|Actinobacteria	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K17238	ko02010,map02010	M00599	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.38	-	-	BPD_transp_1
CMS1_k127_2934164_5	266117.Rxyl_2069	3.522e-126	409.0	COG0395@1|root,COG0395@2|Bacteria,2GJ3P@201174|Actinobacteria,4CR7Y@84995|Rubrobacteria	84995|Rubrobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17239	ko02010,map02010	M00599	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.38	-	-	BPD_transp_1
CMS1_k127_2934164_3	266117.Rxyl_2068	1.576e-130	425.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4CPPT@84995|Rubrobacteria	84995|Rubrobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K17240	ko02010,map02010	M00599	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.38	-	-	ABC_tran,TOBE_2
CMS1_k127_2934164_4	944480.ATUV01000002_gene132	1.204e-127	422.0	COG0558@1|root,COG1213@1|root,COG0558@2|Bacteria,COG1213@2|Bacteria,1NN43@1224|Proteobacteria,432HN@68525|delta/epsilon subdivisions,2WYCV@28221|Deltaproteobacteria,2M7MC@213113|Desulfurellales	28221|Deltaproteobacteria	IM	CDP-alcohol phosphatidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CDP-OH_P_transf
CMS1_k127_2934164_16	7739.XP_002588185.1	1.634e-57	214.0	COG0620@1|root,KOG2263@2759|Eukaryota,38GZS@33154|Opisthokonta,3BNKS@33208|Metazoa,3DA1V@33213|Bilateria,48QHV@7711|Chordata	33208|Metazoa	E	Cobalamin-independent synthase, Catalytic domain	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
CMS1_k127_2934164_2	314278.NB231_03015	2.005e-133	441.0	2C40F@1|root,33WUG@2|Bacteria,1NWBW@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2934164_9	1231190.NA8A_17333	3.42e-99	334.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQMJ@28211|Alphaproteobacteria,43IZ0@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Belongs to the ABC transporter superfamily	-	-	3.6.3.30	ko:K02010,ko:K02052	ko02010,ko02024,map02010,map02024	M00190,M00193	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10,3.A.1.11	-	-	ABC_tran,TOBE_2
CMS1_k127_2934164_7	935261.JAGL01000013_gene3607	1.001e-114	393.0	COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,2VEX7@28211|Alphaproteobacteria,43R8I@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
CMS1_k127_2934266_0	926550.CLDAP_05510	1.314e-136	442.0	COG1215@1|root,COG1215@2|Bacteria,2G8CP@200795|Chloroflexi	200795|Chloroflexi	M	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2934266_4	926550.CLDAP_05520	1.393e-32	139.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
CMS1_k127_2934266_1	386456.JQKN01000002_gene2723	2.238e-90	310.0	COG0644@1|root,arCOG06720@2157|Archaea	2157|Archaea	C	NAD(P)-binding Rossmann-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HI0933_like
CMS1_k127_2934266_2	933262.AXAM01000145_gene1521	1.019e-59	226.0	COG1672@1|root,COG1672@2|Bacteria,1R4NN@1224|Proteobacteria,42NMV@68525|delta/epsilon subdivisions,2WM2Z@28221|Deltaproteobacteria	2|Bacteria	S	PFAM Archaeal ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_13,AAA_22,AAA_35
CMS1_k127_2934266_3	215803.DB30_5111	1.259e-39	153.0	COG1073@1|root,COG1073@2|Bacteria,1Q92N@1224|Proteobacteria,437Z1@68525|delta/epsilon subdivisions,2WZRJ@28221|Deltaproteobacteria,2YUVK@29|Myxococcales	28221|Deltaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
CMS1_k127_2934870_1	1521187.JPIM01000132_gene1331	1.193e-52	194.0	2EDBT@1|root,33781@2|Bacteria,2G8Y5@200795|Chloroflexi,376V2@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2934870_3	1128421.JAGA01000002_gene322	1.597e-19	98.0	298EI@1|root,2ZVJR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2934870_0	485913.Krac_10529	9.19e-120	419.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,2G6X4@200795|Chloroflexi	200795|Chloroflexi	S	PFAM TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12
CMS1_k127_2934870_4	485913.Krac_11964	3.474e-17	96.0	COG1404@1|root,COG1404@2|Bacteria,2G9ID@200795|Chloroflexi	200795|Chloroflexi	O	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
CMS1_k127_2934870_2	671143.DAMO_2422	1.019e-30	140.0	28VTP@1|root,2ZHVD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2937058_4	1394178.AWOO02000001_gene1331	1.542e-56	210.0	COG0673@1|root,COG0673@2|Bacteria,2IMUZ@201174|Actinobacteria	201174|Actinobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_2937058_3	1121861.KB899921_gene2969	2.457e-98	334.0	COG4948@1|root,COG4948@2|Bacteria,1MW5B@1224|Proteobacteria,2UNXP@28211|Alphaproteobacteria,2JQXX@204441|Rhodospirillales	204441|Rhodospirillales	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
CMS1_k127_2937058_1	658086.HMPREF0994_00389	1.361e-132	437.0	COG3119@1|root,COG3119@2|Bacteria,1TQEP@1239|Firmicutes,2482B@186801|Clostridia,27P18@186928|unclassified Lachnospiraceae	186801|Clostridia	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS1_k127_2937058_0	1227488.C477_09779	3.772e-154	497.0	COG4948@1|root,arCOG01168@2157|Archaea,2XTJY@28890|Euryarchaeota,23UMD@183963|Halobacteria	183963|Halobacteria	M	COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily	dgoA2	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
CMS1_k127_2937058_2	428125.CLOLEP_02804	9.352e-119	392.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	1.1.99.28	ko:K00118	-	-	-	-	ko00000,ko01000	-	-	-	GFO_IDH_MocA
CMS1_k127_2937058_5	1460640.JCM19046_4999	1.941e-54	202.0	COG0395@1|root,COG0395@2|Bacteria,1TQG0@1239|Firmicutes,4HD6Q@91061|Bacilli,1ZAVF@1386|Bacillus	91061|Bacilli	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K10242	ko02010,map02010	M00206	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.23	-	-	BPD_transp_1
CMS1_k127_2937058_6	649638.Trad_1730	4.441e-29	119.0	COG1175@1|root,COG1175@2|Bacteria,1WJMX@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025,ko:K10189	ko02010,map02010	M00199,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.4	-	-	BPD_transp_1
CMS1_k127_2938810_0	1121405.dsmv_1320	0.0	1358.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,42NDJ@68525|delta/epsilon subdivisions,2WJSH@28221|Deltaproteobacteria,2MIZ3@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
CMS1_k127_2938810_2	326427.Cagg_1320	3.097e-59	221.0	COG0477@1|root,COG2814@2|Bacteria,2G6MT@200795|Chloroflexi,375W2@32061|Chloroflexia	32061|Chloroflexia	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	ko:K08223	-	-	-	-	ko00000,ko02000	2.A.1.35	-	-	MFS_1
CMS1_k127_2938810_3	926550.CLDAP_21840	3.559e-41	157.0	COG1495@1|root,COG2010@1|root,COG1495@2|Bacteria,COG2010@2|Bacteria,2G90A@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Disulphide bond formation protein DsbB	-	-	-	ko:K03611	-	-	-	-	ko00000,ko03110	5.A.2.1	-	-	DsbB
CMS1_k127_2938810_1	926550.CLDAP_27230	3.903e-77	263.0	COG1051@1|root,COG1051@2|Bacteria,2G7EC@200795|Chloroflexi	200795|Chloroflexi	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX,Nudix_N
CMS1_k127_2938810_4	326427.Cagg_1398	1.839e-29	125.0	COG0303@1|root,COG0303@2|Bacteria,2G99Q@200795|Chloroflexi,3772N@32061|Chloroflexia	32061|Chloroflexia	H	PFAM molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
CMS1_k127_294758_1	1144310.PMI07_006265	3.537e-118	409.0	COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,2TR0J@28211|Alphaproteobacteria,4BNVN@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02031,ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,BPD_transp_1,oligo_HPY
CMS1_k127_294758_0	324602.Caur_1362	1.371e-214	681.0	COG0747@1|root,COG0747@2|Bacteria	2|Bacteria	E	dipeptide transport	ophA	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_294758_2	926550.CLDAP_22290	1.626e-35	137.0	COG2986@1|root,COG2986@2|Bacteria,2G66R@200795|Chloroflexi	200795|Chloroflexi	E	PFAM phenylalanine histidine ammonia-lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
CMS1_k127_2953926_2	658086.HMPREF0994_07170	4.55e-25	108.0	COG3664@1|root,COG3664@2|Bacteria,1V626@1239|Firmicutes,24C45@186801|Clostridia	186801|Clostridia	G	Glycosyl hydrolases family 39	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_39
CMS1_k127_2953926_0	1120950.KB892768_gene5204	2.618e-253	800.0	COG1123@1|root,COG4172@2|Bacteria,2H3HY@201174|Actinobacteria,4DN37@85009|Propionibacteriales	201174|Actinobacteria	O	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
CMS1_k127_2953926_1	649638.Trad_1851	1.366e-165	528.0	COG1173@1|root,COG1173@2|Bacteria,1WJDE@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EP	COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
CMS1_k127_2955766_7	926550.CLDAP_31690	1.464e-06	51.0	COG1028@1|root,COG1028@2|Bacteria,2G8KA@200795|Chloroflexi	200795|Chloroflexi	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS1_k127_2955766_5	317936.Nos7107_4991	2.137e-64	229.0	COG4636@1|root,COG4636@2|Bacteria,1G1QP@1117|Cyanobacteria,1HMX6@1161|Nostocales	1117|Cyanobacteria	S	COGs COG4636 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF4351,Uma2
CMS1_k127_2955766_0	314278.NB231_11184	1.467e-197	622.0	COG0517@1|root,COG0538@1|root,COG0517@2|Bacteria,COG0538@2|Bacteria,1MW3J@1224|Proteobacteria,1RNMD@1236|Gammaproteobacteria,1WVYY@135613|Chromatiales	135613|Chromatiales	C	TIGRFAM isocitrate dehydrogenase, NADP-dependent	-	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,Iso_dh
CMS1_k127_2955766_3	1521187.JPIM01000013_gene2753	5.795e-93	318.0	COG0142@1|root,COG0142@2|Bacteria,2G6BM@200795|Chloroflexi,3755H@32061|Chloroflexia	32061|Chloroflexia	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
CMS1_k127_2955766_4	525904.Tter_2507	1.616e-92	312.0	COG0395@1|root,COG0395@2|Bacteria	2|Bacteria	P	glycerophosphodiester transmembrane transport	-	-	-	ko:K02026,ko:K05815	ko02010,map02010	M00198,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.3	-	-	BPD_transp_1
CMS1_k127_2955766_2	697281.Mahau_2566	1.266e-93	317.0	COG1175@1|root,COG1175@2|Bacteria,1TPTZ@1239|Firmicutes,2492R@186801|Clostridia,42FXR@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_2955766_6	1120950.KB892746_gene3500	1.717e-28	130.0	COG1653@1|root,COG1653@2|Bacteria,2HFIW@201174|Actinobacteria,4DTUT@85009|Propionibacteriales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_1
CMS1_k127_2955766_1	926569.ANT_20510	2.27e-112	369.0	COG1304@1|root,COG1304@2|Bacteria,2G5RF@200795|Chloroflexi	200795|Chloroflexi	H	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)	fni	-	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	FMN_dh
CMS1_k127_2956135_5	595460.RRSWK_05572	1.14e-05	47.0	COG1070@1|root,COG1070@2|Bacteria,2IX0P@203682|Planctomycetes	203682|Planctomycetes	F	COG1070 Sugar (pentulose and hexulose)	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
CMS1_k127_2956135_2	575540.Isop_0353	2.343e-33	132.0	COG1070@1|root,COG1070@2|Bacteria,2IX0P@203682|Planctomycetes	203682|Planctomycetes	F	COG1070 Sugar (pentulose and hexulose)	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
CMS1_k127_2956135_0	622637.KE124774_gene479	6.851e-107	359.0	COG1960@1|root,COG1960@2|Bacteria,1MXMQ@1224|Proteobacteria,2U0CV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	acyl-CoA dehydrogenase	-	-	1.14.13.235	ko:K22027	-	-	-	-	ko00000,ko01000	-	-	-	Acyl-CoA_dh_2,Acyl-CoA_dh_N
CMS1_k127_2956135_3	926550.CLDAP_29560	5.24e-18	90.0	COG3743@1|root,COG3743@2|Bacteria,2G8N1@200795|Chloroflexi	200795|Chloroflexi	S	Jacalin-like lectin domain	-	-	-	-	-	-	-	-	-	-	-	-	HHH_5,Jacalin
CMS1_k127_2956135_1	485913.Krac_9268	2.986e-56	206.0	COG1028@1|root,COG1028@2|Bacteria	485913.Krac_9268|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2956135_4	1206729.BAFZ01000155_gene5842	3.601e-16	91.0	COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4FUTU@85025|Nocardiaceae	201174|Actinobacteria	K	activity, protein serine threonine kinase activity, protein-tyrosine kinase activity, ATP binding, regulation of transcription, DNA-dependent, protein amino acid phosphorylation	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_22,GerE,NB-ARC,Response_reg,TPR_12,Trans_reg_C
CMS1_k127_2962917_4	1120973.AQXL01000122_gene191	2.611e-47	183.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,4HAM7@91061|Bacilli,278QJ@186823|Alicyclobacillaceae	91061|Bacilli	E	Bacterial extracellular solute-binding proteins, family 5 Middle	dppA_1	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_2962917_1	479434.Sthe_0679	6.235e-98	329.0	COG0601@1|root,COG0601@2|Bacteria,2G6BV@200795|Chloroflexi,27XFE@189775|Thermomicrobia	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_2962917_2	479434.Sthe_0975	2.059e-81	281.0	COG1173@1|root,COG1173@2|Bacteria,2G6HB@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
CMS1_k127_2962917_3	479434.Sthe_1133	1.207e-47	188.0	2DYB6@1|root,3490S@2|Bacteria	479434.Sthe_1133|-	S	Polysaccharide lyase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2962917_6	1142394.PSMK_31470	2.341e-05	57.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR
CMS1_k127_2962917_5	485913.Krac_10911	2.086e-41	159.0	COG4636@1|root,COG4636@2|Bacteria,2G90F@200795|Chloroflexi	200795|Chloroflexi	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
CMS1_k127_2962917_0	926550.CLDAP_07340	0.0	1097.0	COG0542@1|root,COG0542@2|Bacteria,2G5QU@200795|Chloroflexi	200795|Chloroflexi	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
CMS1_k127_296427_2	344747.PM8797T_31563	4.247e-39	154.0	COG0624@1|root,COG0624@2|Bacteria,2IYPQ@203682|Planctomycetes	203682|Planctomycetes	E	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate	-	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M42
CMS1_k127_296427_1	1385935.N836_32250	5.558e-61	216.0	2A53S@1|root,30TSD@2|Bacteria,1GGW0@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_296427_0	196162.Noca_1338	1.048e-90	312.0	COG1215@1|root,COG3266@1|root,COG1215@2|Bacteria,COG3266@2|Bacteria,2GKFI@201174|Actinobacteria,4DPBK@85009|Propionibacteriales	201174|Actinobacteria	M	Glycosyl transferase family group 2	-	-	2.4.1.12	ko:K00694	ko00500,ko01100,ko02026,map00500,map01100,map02026	-	R02889	RC00005	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.3.1.2,4.D.3.1.5,4.D.3.1.6	GT2	-	Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2
CMS1_k127_2964525_3	765420.OSCT_1229	1.449e-28	122.0	COG0745@1|root,COG0745@2|Bacteria	765420.OSCT_1229|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2964525_1	765420.OSCT_1228	4.904e-82	301.0	COG3437@1|root,COG5002@1|root,COG3437@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF,GAF_2,HATPase_c,HisKA,HisKA_3,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
CMS1_k127_2964525_0	457570.Nther_2872	4.037e-141	456.0	COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,248CN@186801|Clostridia	186801|Clostridia	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
CMS1_k127_2964525_5	929712.KI912613_gene4279	7.509e-07	53.0	2A5VU@1|root,30UMP@2|Bacteria,2HRRK@201174|Actinobacteria,4CTU7@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2964525_4	1521187.JPIM01000126_gene243	6.764e-08	62.0	2CHCV@1|root,33I5B@2|Bacteria,2GB6U@200795|Chloroflexi,377GN@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2964525_2	926569.ANT_08030	1.466e-67	263.0	COG1361@1|root,COG3764@1|root,COG1361@2|Bacteria,COG3764@2|Bacteria,2G854@200795|Chloroflexi	200795|Chloroflexi	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
CMS1_k127_2972922_29	479434.Sthe_0666	9.751e-14	73.0	COG0405@1|root,COG0405@2|Bacteria,2G5R2@200795|Chloroflexi	2|Bacteria	E	PFAM Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
CMS1_k127_2972922_23	272123.Anacy_2457	1.785e-21	112.0	COG1122@1|root,COG2319@1|root,COG1122@2|Bacteria,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1HQSK@1161|Nostocales	1117|Cyanobacteria	P	PFAM WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,WD40
CMS1_k127_2972922_6	118168.MC7420_7038	1.262e-90	340.0	COG0515@1|root,COG2114@1|root,COG5635@1|root,COG0515@2|Bacteria,COG2114@2|Bacteria,COG5635@2|Bacteria,1G14T@1117|Cyanobacteria,1H8RF@1150|Oscillatoriales	1117|Cyanobacteria	T	Ntpase (Nacht family)	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	NACHT,Pkinase,TIR_2
CMS1_k127_2972922_22	32057.KB217478_gene5685	1.267e-23	119.0	COG2319@1|root,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1HKN5@1161|Nostocales	1117|Cyanobacteria	S	PFAM WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	AAA_35,WD40
CMS1_k127_2972922_13	272134.KB731324_gene5053	4.018e-50	194.0	COG2319@1|root,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria	1117|Cyanobacteria	A	WD domain, G-beta repeat	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Peptidase_C14,TIR_2,WD40
CMS1_k127_2972922_24	489825.LYNGBM3L_17100	1.292e-19	102.0	COG4252@1|root,COG5635@1|root,COG4252@2|Bacteria,COG5635@2|Bacteria,1G14T@1117|Cyanobacteria,1H8RF@1150|Oscillatoriales	1117|Cyanobacteria	T	Ntpase (Nacht family)	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,NACHT,Pkinase
CMS1_k127_2972922_19	324602.Caur_2747	3.122e-29	123.0	COG2852@1|root,COG2852@2|Bacteria,2GAFN@200795|Chloroflexi,375Y8@32061|Chloroflexia	32061|Chloroflexia	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2972922_14	251221.35214981	5.542e-41	158.0	COG5516@1|root,COG5516@2|Bacteria	2|Bacteria	S	CGNR zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	ABATE,zf-CGNR
CMS1_k127_2972922_30	235985.BBPN01000019_gene5967	3.634e-11	68.0	COG0477@1|root,COG2814@2|Bacteria,2GMKX@201174|Actinobacteria,2NHG4@228398|Streptacidiphilus	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
CMS1_k127_2972922_4	1128421.JAGA01000002_gene165	6.079e-114	377.0	COG2896@1|root,COG2896@2|Bacteria,2NP5R@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0030312,GO:0040007,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0071944,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.22,4.6.1.17	ko:K03639,ko:K20967	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394,R11372	RC03420,RC03425	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
CMS1_k127_2972922_16	926569.ANT_17990	8.143e-34	138.0	COG2345@1|root,COG2345@2|Bacteria,2G79S@200795|Chloroflexi	200795|Chloroflexi	K	PFAM regulatory protein, ArsR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
CMS1_k127_2972922_0	886293.Sinac_5547	3.296e-264	837.0	COG0377@1|root,COG0649@1|root,COG0852@1|root,COG0377@2|Bacteria,COG0649@2|Bacteria,COG0852@2|Bacteria,2IYN8@203682|Planctomycetes	203682|Planctomycetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
CMS1_k127_2972922_12	926569.ANT_18220	1.764e-56	210.0	COG1143@1|root,COG1143@2|Bacteria,2G6SE@200795|Chloroflexi	200795|Chloroflexi	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	1.6.5.3	ko:K00338,ko:K03615	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
CMS1_k127_2972922_18	1128421.JAGA01000002_gene182	2.056e-29	124.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	DZR,FHA,zinc_ribbon_2
CMS1_k127_2972922_17	383372.Rcas_2697	4.711e-33	136.0	COG1595@1|root,COG1595@2|Bacteria,2G99U@200795|Chloroflexi	200795|Chloroflexi	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_2972922_21	646529.Desaci_1130	9.552e-25	117.0	COG5662@1|root,COG5662@2|Bacteria,1U13D@1239|Firmicutes,24AF3@186801|Clostridia,262HU@186807|Peptococcaceae	186801|Clostridia	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	DUF2275,DUF4367,zf-HC2
CMS1_k127_2972922_5	526227.Mesil_0789	4.794e-101	339.0	COG1131@1|root,COG1131@2|Bacteria,1WJ0H@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_2972922_10	383372.Rcas_3764	6.853e-69	243.0	COG1277@1|root,COG1277@2|Bacteria,2G79P@200795|Chloroflexi	200795|Chloroflexi	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
CMS1_k127_2972922_15	1220534.B655_1045	9.188e-38	164.0	COG0457@1|root,COG0515@1|root,arCOG03038@2157|Archaea,arCOG03682@2157|Archaea,2XYM9@28890|Euryarchaeota,23PP8@183925|Methanobacteria	183925|Methanobacteria	T	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_8
CMS1_k127_2972922_9	926550.CLDAP_34380	1.273e-69	246.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS1_k127_2972922_26	1121481.AUAS01000013_gene4209	5.467e-18	95.0	COG1295@1|root,COG1295@2|Bacteria,4NFG8@976|Bacteroidetes,47MDF@768503|Cytophagia	976|Bacteroidetes	S	ribonuclease BN	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
CMS1_k127_2972922_27	383372.Rcas_2516	2.008e-17	96.0	COG3408@1|root,COG3408@2|Bacteria,2G8AC@200795|Chloroflexi	200795|Chloroflexi	G	Alkaline and neutral invertase	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,Glyco_hydro_100
CMS1_k127_2972922_2	1122915.AUGY01000004_gene5551	3.778e-127	414.0	COG2040@1|root,COG2040@2|Bacteria,1UHQ5@1239|Firmicutes,4HAS6@91061|Bacilli,26TIZ@186822|Paenibacillaceae	91061|Bacilli	E	Homocysteine S-methyltransferase	mmuM	-	2.1.1.10	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	-	R00650	RC00003,RC00035	ko00000,ko00001,ko01000	-	-	-	S-methyl_trans
CMS1_k127_2972922_20	867903.ThesuDRAFT_01639	3.609e-27	117.0	COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,24QPP@186801|Clostridia,3WDCK@538999|Clostridiales incertae sedis	186801|Clostridia	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
CMS1_k127_2972922_7	326427.Cagg_2289	1.949e-83	287.0	COG0564@1|root,COG0564@2|Bacteria,2G68N@200795|Chloroflexi,3758V@32061|Chloroflexia	32061|Chloroflexia	J	Responsible for synthesis of pseudouridine from uracil	-	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
CMS1_k127_2972922_31	1077974.GOEFS_106_01060	8.488e-07	61.0	COG1388@1|root,COG1388@2|Bacteria,2IECN@201174|Actinobacteria,4GGDT@85026|Gordoniaceae	201174|Actinobacteria	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
CMS1_k127_2972922_3	1499967.BAYZ01000104_gene3692	2.141e-116	387.0	COG0738@1|root,COG0738@2|Bacteria	2|Bacteria	G	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_2972922_25	1185653.A1A1_14134	1.033e-18	93.0	2E175@1|root,32WMX@2|Bacteria,1V5R3@1239|Firmicutes,4HI53@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2972922_11	1121405.dsmv_3719	6.768e-63	228.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,42MDR@68525|delta/epsilon subdivisions,2WKUR@28221|Deltaproteobacteria,2MI64@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS1_k127_2972922_8	926550.CLDAP_09300	1.892e-73	258.0	COG0506@1|root,COG0506@2|Bacteria,2G6B6@200795|Chloroflexi	200795|Chloroflexi	C	Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
CMS1_k127_2972922_1	326427.Cagg_0585	1.427e-142	456.0	COG1109@1|root,COG1109@2|Bacteria,2G5YP@200795|Chloroflexi,3756A@32061|Chloroflexia	32061|Chloroflexia	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
CMS1_k127_2991290_3	1535287.JP74_00905	1.747e-32	140.0	COG1653@1|root,COG1653@2|Bacteria,1NC43@1224|Proteobacteria,2U3SD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1
CMS1_k127_2991290_1	86416.Clopa_3703	5.869e-83	284.0	COG0395@1|root,COG0395@2|Bacteria,1TRCP@1239|Firmicutes,25C50@186801|Clostridia,36WPD@31979|Clostridiaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_2991290_0	935948.KE386494_gene700	7.334e-90	304.0	COG1175@1|root,COG1175@2|Bacteria,1TREE@1239|Firmicutes,24B75@186801|Clostridia,42I1V@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025,ko:K05814	ko02010,map02010	M00198,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.3	-	-	BPD_transp_1
CMS1_k127_2991290_2	1122915.AUGY01000010_gene4620	4.73e-77	270.0	COG1609@1|root,COG1609@2|Bacteria,1TRZW@1239|Firmicutes,4HD7B@91061|Bacilli,274HM@186822|Paenibacillaceae	91061|Bacilli	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529,ko:K03435	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
CMS1_k127_299132_2	326423.RBAM_015590	5.909e-33	136.0	COG0631@1|root,COG0631@2|Bacteria,1V6K5@1239|Firmicutes,4HCDR@91061|Bacilli,1ZCYC@1386|Bacillus	91061|Bacilli	T	phosphatase	stp	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
CMS1_k127_299132_1	304371.MCP_2981	4.207e-33	133.0	COG0456@1|root,arCOG00833@2157|Archaea,2XXV1@28890|Euryarchaeota	28890|Euryarchaeota	S	COG1246 N-acetylglutamate synthase and related acetyltransferases	-	-	2.3.1.1	ko:K00619	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
CMS1_k127_299132_0	926569.ANT_11080	2.033e-91	307.0	COG1486@1|root,COG1486@2|Bacteria,2G6IX@200795|Chloroflexi	200795|Chloroflexi	G	Family 4 glycosyl hydrolase	-	-	3.2.1.86	ko:K01222	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT4	-	Glyco_hydro_4,Glyco_hydro_4C
CMS1_k127_299132_3	926569.ANT_11080	1.485e-28	115.0	COG1486@1|root,COG1486@2|Bacteria,2G6IX@200795|Chloroflexi	200795|Chloroflexi	G	Family 4 glycosyl hydrolase	-	-	3.2.1.86	ko:K01222	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT4	-	Glyco_hydro_4,Glyco_hydro_4C
CMS1_k127_3009857_12	383372.Rcas_0166	3.93e-25	109.0	COG1187@1|root,COG1187@2|Bacteria,2G6HU@200795|Chloroflexi,375DQ@32061|Chloroflexia	32061|Chloroflexia	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
CMS1_k127_3009857_6	926569.ANT_10810	1.76e-63	225.0	COG0283@1|root,COG0283@2|Bacteria,2G6I5@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
CMS1_k127_3009857_11	926550.CLDAP_22180	1.405e-28	126.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
CMS1_k127_3009857_13	383372.Rcas_2105	5.731e-22	104.0	2DVVU@1|root,33XEF@2|Bacteria,2GAEW@200795|Chloroflexi,375UZ@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3009857_5	316274.Haur_0454	4.806e-64	228.0	COG0321@1|root,COG0321@2|Bacteria,2G8KT@200795|Chloroflexi,375KR@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
CMS1_k127_3009857_1	926550.CLDAP_12660	9.195e-125	408.0	COG0320@1|root,COG0320@2|Bacteria,2G5MH@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
CMS1_k127_3009857_9	485913.Krac_9978	8.981e-41	164.0	COG0451@1|root,COG0451@2|Bacteria,2G84M@200795|Chloroflexi	200795|Chloroflexi	M	PFAM NAD-dependent epimerase dehydratase	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
CMS1_k127_3009857_10	926569.ANT_03640	1.016e-38	154.0	COG0746@1|root,COG0746@2|Bacteria	2|Bacteria	H	molybdenum cofactor guanylyltransferase activity	mobA	GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.77	ko:K03752,ko:K13818	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
CMS1_k127_3009857_14	926561.KB900621_gene2849	8.82e-12	72.0	COG0671@1|root,COG0671@2|Bacteria,1VB7J@1239|Firmicutes,24JDD@186801|Clostridia,3WBWE@53433|Halanaerobiales	186801|Clostridia	I	PAP2 superfamily	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
CMS1_k127_3009857_0	479434.Sthe_1183	3.408e-154	503.0	COG4262@1|root,COG4262@2|Bacteria,2G5YS@200795|Chloroflexi	200795|Chloroflexi	S	Spermine/spermidine synthase domain	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
CMS1_k127_3009857_7	1499967.BAYZ01000007_gene5399	3.135e-63	228.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	mhpC	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
CMS1_k127_3009857_2	869210.Marky_2126	5.164e-122	402.0	COG0477@1|root,COG2814@2|Bacteria,1WIWD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_3009857_4	926550.CLDAP_21440	2.832e-71	269.0	COG4485@1|root,COG4485@2|Bacteria,2G75F@200795|Chloroflexi	200795|Chloroflexi	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
CMS1_k127_3009857_8	1313304.CALK_1537	1.809e-57	208.0	COG0467@1|root,COG0467@2|Bacteria	2|Bacteria	T	regulation of circadian rhythm	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
CMS1_k127_3009857_3	926569.ANT_04080	1.356e-104	347.0	COG0143@1|root,COG0143@2|Bacteria,2G5ZU@200795|Chloroflexi	200795|Chloroflexi	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g
CMS1_k127_3020989_4	304371.MCP_2710	2.716e-62	226.0	COG0438@1|root,arCOG01403@2157|Archaea,2XTRH@28890|Euryarchaeota	28890|Euryarchaeota	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS1_k127_3020989_7	926550.CLDAP_27730	1.153e-48	191.0	COG0438@1|root,COG0438@2|Bacteria,2G7Z3@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CMS1_k127_3020989_3	331678.Cphamn1_2145	1.552e-84	289.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
CMS1_k127_3020989_6	1353537.TP2_17355	3.673e-52	199.0	COG0438@1|root,COG0438@2|Bacteria,1PHS8@1224|Proteobacteria,2UI5U@28211|Alphaproteobacteria,2XPI3@285107|Thioclava	28211|Alphaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS1_k127_3020989_8	768671.ThimaDRAFT_1972	7.245e-24	113.0	COG1216@1|root,COG1216@2|Bacteria,1RJPX@1224|Proteobacteria,1S1SB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Glycosyltransferase like family 2	-	-	2.4.1.175,2.4.1.226	ko:K13500	ko00532,ko01100,map00532,map01100	-	R04603,R05931,R05932,R05933,R05934,R07336	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glyco_transf_7C,Glycos_transf_2
CMS1_k127_3020989_2	926569.ANT_20310	6.364e-92	319.0	COG3307@1|root,COG3307@2|Bacteria,2G7A2@200795|Chloroflexi	200795|Chloroflexi	M	PFAM O-antigen polymerase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
CMS1_k127_3020989_1	926569.ANT_20320	1.078e-103	345.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
CMS1_k127_3020989_0	926550.CLDAP_18760	2.669e-273	851.0	COG0529@1|root,COG2046@1|root,COG0529@2|Bacteria,COG2046@2|Bacteria,2G7JD@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the synthesis of activated sulfate	cysC	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,ATP-sulfurylase,PUA_2
CMS1_k127_302154_3	324602.Caur_0619	1.006e-88	300.0	COG2379@1|root,COG2379@2|Bacteria,2G5RZ@200795|Chloroflexi,374XG@32061|Chloroflexia	32061|Chloroflexia	C	PFAM MOFRL domain protein	-	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
CMS1_k127_302154_5	706587.Desti_4173	7.001e-55	208.0	COG1215@1|root,COG1215@2|Bacteria,1QVA1@1224|Proteobacteria,43BP8@68525|delta/epsilon subdivisions,2X70I@28221|Deltaproteobacteria,2MSKJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Glycosyltransferase like family 2	-	-	2.4.1.268	ko:K21349	-	-	-	-	ko00000,ko01000	-	GT81	-	Glycos_transf_2
CMS1_k127_302154_0	926569.ANT_31260	1.476e-171	551.0	COG1109@1|root,COG1109@2|Bacteria,2G5PR@200795|Chloroflexi	200795|Chloroflexi	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
CMS1_k127_302154_4	525904.Tter_2296	8.469e-83	284.0	COG0484@1|root,COG0484@2|Bacteria,2NQI8@2323|unclassified Bacteria	2|Bacteria	O	DnaJ molecular chaperone homology domain	cbpA	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
CMS1_k127_302154_7	1122222.AXWR01000043_gene2564	5.28e-31	132.0	COG1011@1|root,COG1011@2|Bacteria,1WI88@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
CMS1_k127_302154_1	926569.ANT_18850	1.832e-150	480.0	COG2152@1|root,COG2152@2|Bacteria,2G6ZE@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycosidase PH1107-related	-	-	2.4.1.319,2.4.1.320,2.4.1.339,2.4.1.340	ko:K18785,ko:K20885	-	-	R10811,R10829,R11397,R11398	RC00049,RC02748	ko00000,ko01000	-	GH130	-	Glyco_hydro_130
CMS1_k127_302154_6	1128421.JAGA01000001_gene2006	2.1e-38	148.0	COG2363@1|root,COG2363@2|Bacteria,2NRMS@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function (DUF423)	ywdK	-	-	-	-	-	-	-	-	-	-	-	DUF423
CMS1_k127_302154_2	1408254.T458_10430	2.121e-130	431.0	COG1164@1|root,COG1164@2|Bacteria,1TQ5W@1239|Firmicutes,4HAN9@91061|Bacilli,26S6W@186822|Paenibacillaceae	91061|Bacilli	E	oligoendopeptidase	pepF2	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M3,Peptidase_M3_N
CMS1_k127_302242_1	1205753.A989_04451	3.088e-30	129.0	2EIP2@1|root,33CEF@2|Bacteria,1QSUQ@1224|Proteobacteria,1RWF0@1236|Gammaproteobacteria,1X3GT@135614|Xanthomonadales	135614|Xanthomonadales	S	Uncharacterised nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
CMS1_k127_302242_3	682795.AciX8_0910	1.111e-13	82.0	COG1493@1|root,COG1493@2|Bacteria,3Y4YI@57723|Acidobacteria,2JK5E@204432|Acidobacteriia	204432|Acidobacteriia	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_302242_4	555079.Toce_0862	5.978e-13	78.0	COG1387@1|root,COG1387@2|Bacteria,1TQ33@1239|Firmicutes,24CMU@186801|Clostridia,42FE9@68295|Thermoanaerobacterales	186801|Clostridia	E	pfam php	-	-	-	ko:K04477	-	-	-	-	ko00000	-	-	-	PHP
CMS1_k127_302242_2	926550.CLDAP_34220	2.946e-26	109.0	COG1278@1|root,COG1278@2|Bacteria,2G7EU@200795|Chloroflexi	200795|Chloroflexi	K	'Cold-shock' DNA-binding domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
CMS1_k127_302242_0	479434.Sthe_3404	4.288e-64	235.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1,Glycos_transf_2
CMS1_k127_3027864_7	1121937.AUHJ01000002_gene3537	5.121e-56	199.0	COG3695@1|root,COG3695@2|Bacteria,1RI04@1224|Proteobacteria,1SN3B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
CMS1_k127_3027864_11	211586.SO_4069	4.872e-18	93.0	COG0500@1|root,COG2226@2|Bacteria,1N9JV@1224|Proteobacteria,1RP9E@1236|Gammaproteobacteria,2QA0U@267890|Shewanellaceae	1236|Gammaproteobacteria	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS1_k127_3027864_8	526227.Mesil_2170	3.457e-41	153.0	COG2329@1|root,COG2329@2|Bacteria,1WK6V@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	involved in biosynthesis of extracellular polysaccharides	-	-	-	-	-	-	-	-	-	-	-	-	ABM
CMS1_k127_3027864_1	485913.Krac_5774	1.232e-122	400.0	COG0384@1|root,COG0384@2|Bacteria	2|Bacteria	S	isomerase activity	-	-	5.3.3.17	ko:K06998	ko00405,ko01130,ko02024,map00405,map01130,map02024	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	PhzC-PhzF
CMS1_k127_3027864_9	330084.JNYZ01000008_gene6609	1.186e-28	121.0	COG1142@1|root,COG1142@2|Bacteria,2IQSG@201174|Actinobacteria	201174|Actinobacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3027864_3	263358.VAB18032_19125	6.148e-97	327.0	COG2141@1|root,COG2141@2|Bacteria,2HVHB@201174|Actinobacteria,4DH6S@85008|Micromonosporales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	1.5.98.2	ko:K00320	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R04464	RC01607	ko00000,ko00001,ko00002,ko01000	-	-	-	Bac_luciferase
CMS1_k127_3027864_12	926550.CLDAP_22360	2.649e-16	83.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_3027864_4	357808.RoseRS_0293	4.149e-82	295.0	COG0308@1|root,COG0308@2|Bacteria,2G75V@200795|Chloroflexi,375Q4@32061|Chloroflexia	32061|Chloroflexia	M	PFAM peptidase M1, membrane alanine aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
CMS1_k127_3027864_5	1499967.BAYZ01000104_gene3636	7.902e-75	268.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K02027,ko:K10117	ko02010,map02010	M00196,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8,TAT_signal
CMS1_k127_3027864_6	309801.trd_0802	1.84e-63	226.0	COG1189@1|root,COG1189@2|Bacteria,2G6BX@200795|Chloroflexi,27XW2@189775|Thermomicrobia	189775|Thermomicrobia	J	FtsJ-like methyltransferase	-	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
CMS1_k127_3027864_10	479434.Sthe_3410	1.509e-20	102.0	COG0500@1|root,COG2890@1|root,COG2226@2|Bacteria,COG2890@2|Bacteria,2G9F9@200795|Chloroflexi	200795|Chloroflexi	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3027864_0	1122134.KB893650_gene563	6.273e-177	574.0	COG5276@1|root,COG5276@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,CarboxypepD_reg,LVIVD,TSP_3
CMS1_k127_3027864_2	658086.HMPREF0994_03756	4.715e-115	386.0	COG1486@1|root,COG1486@2|Bacteria,1V6E5@1239|Firmicutes,24KU5@186801|Clostridia	186801|Clostridia	G	Family 4 glycosyl hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_4,Glyco_hydro_4C
CMS1_k127_3027864_13	1168065.DOK_17085	5.499e-08	63.0	COG0500@1|root,COG2226@2|Bacteria,1R3QX@1224|Proteobacteria,1RYQ8@1236|Gammaproteobacteria,1J5CI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG0500 SAM-dependent methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
CMS1_k127_3034654_0	4641.GSMUA_Achr8P23070_001	1.916e-149	486.0	COG0191@1|root,COG2084@1|root,KOG0409@2759|Eukaryota,KOG4153@2759|Eukaryota,37I1B@33090|Viridiplantae,3GEGM@35493|Streptophyta,3KQKR@4447|Liliopsida	35493|Streptophyta	G	Ketose-bisphosphate aldolase class-II family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1357_C,DUF1537,F_bP_aldolase,NAD_binding_11,NAD_binding_2
CMS1_k127_3034654_1	395961.Cyan7425_4035	2.694e-116	381.0	COG0191@1|root,COG0191@2|Bacteria,1G251@1117|Cyanobacteria,3KGY4@43988|Cyanothece	1117|Cyanobacteria	G	PFAM ketose-bisphosphate aldolase class-II	-	-	4.1.2.40	ko:K08302	ko00052,ko01100,map00052,map01100	-	R01069	RC00438,RC00439	ko00000,ko00001,ko01000	-	-	-	F_bP_aldolase
CMS1_k127_3034654_3	926569.ANT_07850	4.872e-89	300.0	COG2120@1|root,COG2120@2|Bacteria,2G6FB@200795|Chloroflexi	200795|Chloroflexi	S	PFAM LmbE family protein	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
CMS1_k127_3034654_2	1144275.COCOR_00559	5.9e-103	343.0	COG1718@1|root,COG1718@2|Bacteria,1N7US@1224|Proteobacteria,43BB3@68525|delta/epsilon subdivisions,2X6Q8@28221|Deltaproteobacteria,2YTY8@29|Myxococcales	28221|Deltaproteobacteria	DT	Serine threonine protein kinase involved in cell cycle control	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3034654_4	378806.STAUR_8011	1.046e-39	153.0	2CP0Z@1|root,32SI8@2|Bacteria,1RK5X@1224|Proteobacteria,434SF@68525|delta/epsilon subdivisions,2X904@28221|Deltaproteobacteria,2Z0HI@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3037)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3037
CMS1_k127_303738_1	1173024.KI912153_gene217	4.081e-121	394.0	COG0167@1|root,COG0167@2|Bacteria,1G2B6@1117|Cyanobacteria,1JKMZ@1189|Stigonemataceae	1117|Cyanobacteria	F	Dihydroorotate dehydrogenase	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
CMS1_k127_303738_0	1173024.KI912153_gene216	0.0	1566.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1G2E2@1117|Cyanobacteria,1JKG2@1189|Stigonemataceae	1117|Cyanobacteria	C	Domain of unknown function	-	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C
CMS1_k127_3043946_10	717605.Theco_1531	7.147e-57	207.0	2BVJM@1|root,32QXJ@2|Bacteria,1V8X3@1239|Firmicutes,4HIQ1@91061|Bacilli,26YIN@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3043946_0	867845.KI911784_gene2556	1.511e-201	641.0	COG1574@1|root,COG1574@2|Bacteria,2G85Y@200795|Chloroflexi,37716@32061|Chloroflexia	32061|Chloroflexia	S	PFAM Amidohydrolase 3	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
CMS1_k127_3043946_3	926550.CLDAP_16450	5.825e-129	434.0	COG4166@1|root,COG4166@2|Bacteria,2G81P@200795|Chloroflexi	200795|Chloroflexi	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_3043946_7	479434.Sthe_1895	6.878e-93	315.0	COG1173@1|root,COG1173@2|Bacteria,2G612@200795|Chloroflexi,27XHC@189775|Thermomicrobia	189775|Thermomicrobia	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
CMS1_k127_3043946_6	926550.CLDAP_16460	4.521e-102	341.0	COG0601@1|root,COG0601@2|Bacteria,2G61A@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033,ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
CMS1_k127_3043946_2	935840.JAEQ01000030_gene871	7.718e-140	454.0	COG4948@1|root,COG4948@2|Bacteria,1MW5B@1224|Proteobacteria,2U0FB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Catalyzes the dehydration of L-rhamnonate to 2-keto-3- deoxy-L-rhamnonate (KDR)	rhmD	-	4.2.1.90	ko:K12661	ko00051,ko01120,map00051,map01120	-	R03774	RC00543	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
CMS1_k127_3043946_21	926550.CLDAP_32460	1.367e-11	78.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS1_k127_3043946_16	1128421.JAGA01000003_gene3738	2.447e-24	120.0	COG4745@1|root,COG4745@2|Bacteria	2|Bacteria	O	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS1_k127_3043946_18	926550.CLDAP_17040	3.091e-21	110.0	COG5276@1|root,COG5276@2|Bacteria,2G8F2@200795|Chloroflexi	200795|Chloroflexi	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
CMS1_k127_3043946_9	1121342.AUCO01000009_gene440	4.16e-66	253.0	COG4870@1|root,COG4870@2|Bacteria,1TS2S@1239|Firmicutes,248FU@186801|Clostridia,36EP3@31979|Clostridiaceae	186801|Clostridia	O	Repeat of unknown function (DUF346)	-	-	-	-	-	-	-	-	-	-	-	-	DUF346
CMS1_k127_3043946_22	326427.Cagg_0803	6.732e-06	60.0	COG4409@1|root,COG4409@2|Bacteria,2G76D@200795|Chloroflexi,3763D@32061|Chloroflexia	32061|Chloroflexia	M	BNR repeat-containing family member	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
CMS1_k127_3043946_13	926550.CLDAP_16480	4.709e-39	163.0	COG0745@1|root,COG1672@1|root,COG0745@2|Bacteria,COG1672@2|Bacteria,2G778@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
CMS1_k127_3043946_1	867903.ThesuDRAFT_01827	9.747e-171	552.0	COG2936@1|root,COG2936@2|Bacteria,1TT0H@1239|Firmicutes,24BT1@186801|Clostridia,3WD7J@538999|Clostridiales incertae sedis	186801|Clostridia	S	PFAM X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
CMS1_k127_3043946_4	1449063.JMLS01000005_gene3136	5.059e-123	409.0	COG3119@1|root,COG3119@2|Bacteria,1VAJC@1239|Firmicutes,4I9H8@91061|Bacilli,271IZ@186822|Paenibacillaceae	91061|Bacilli	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS1_k127_3043946_12	1173023.KE650771_gene1703	3.964e-47	173.0	COG1403@1|root,COG1403@2|Bacteria,1G5UG@1117|Cyanobacteria,1JM7J@1189|Stigonemataceae	1117|Cyanobacteria	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH
CMS1_k127_3043946_19	313612.L8106_01782	3.187e-14	78.0	2BWVV@1|root,32R08@2|Bacteria,1G7AG@1117|Cyanobacteria,1HC1N@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3043946_15	1033738.CAEP01000112_gene404	4.342e-26	115.0	2CCGS@1|root,32UCE@2|Bacteria,1V9YN@1239|Firmicutes,4HKU7@91061|Bacilli,26HQI@186818|Planococcaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3043946_14	1123278.KB893433_gene672	1.161e-27	123.0	COG1082@1|root,COG1082@2|Bacteria,4NHMP@976|Bacteroidetes,47NUC@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase domain protein TIM barrel	-	-	4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
CMS1_k127_3043946_5	1210884.HG799464_gene10536	1.581e-102	342.0	COG1453@1|root,COG1453@2|Bacteria,2IZF3@203682|Planctomycetes	203682|Planctomycetes	S	aldo keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS1_k127_3043946_23	1121324.CLIT_2c00500	0.0008703	43.0	COG0596@1|root,COG0596@2|Bacteria,1TSPF@1239|Firmicutes,24AD1@186801|Clostridia,25UB3@186804|Peptostreptococcaceae	186801|Clostridia	S	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS1_k127_3043946_8	35754.JNYJ01000081_gene4180	1.053e-89	300.0	COG0500@1|root,COG2226@2|Bacteria,2I2I5@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS1_k127_3049455_1	867845.KI911784_gene2369	3.742e-146	470.0	COG0002@1|root,COG0002@2|Bacteria,2G5W0@200795|Chloroflexi,374YZ@32061|Chloroflexia	32061|Chloroflexia	E	Catalyzes the NADPH-dependent reduction of LysW - aminoadipate 6-phosphate to yield LysW -aminoadipate 6- semialdehyde	lysY	-	-	ko:K05829	ko00220,ko00300,ko01100,ko01110,ko01210,ko01230,map00220,map00300,map01100,map01110,map01210,map01230	M00031,M00763	R09777,R10931	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh
CMS1_k127_3049455_0	1499967.BAYZ01000088_gene5062	3.701e-160	511.0	COG1167@1|root,COG1167@2|Bacteria,2NQG7@2323|unclassified Bacteria	2|Bacteria	EK	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
CMS1_k127_3049455_2	324602.Caur_0334	3.366e-122	400.0	COG0189@1|root,COG0189@2|Bacteria,2G5RN@200795|Chloroflexi,374VK@32061|Chloroflexia	32061|Chloroflexia	HJ	PFAM ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp	-	-	6.3.2.43	ko:K05827	ko00300,ko01100,ko01210,ko01230,map00300,map01100,map01210,map01230	M00031	R09775	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	RimK
CMS1_k127_3049455_3	324602.Caur_0332	1.476e-18	87.0	2DRHT@1|root,33BTG@2|Bacteria,2G7I1@200795|Chloroflexi,37602@32061|Chloroflexia	32061|Chloroflexia	S	TIGRFAM lysine biosynthesis protein LysW	-	-	-	ko:K05826	-	M00031,M00763	-	-	ko00000,ko00001,ko00002	-	-	-	-
CMS1_k127_305064_4	926569.ANT_08170	1.791e-05	49.0	COG0842@1|root,COG0842@2|Bacteria,2G8VC@200795|Chloroflexi	200795|Chloroflexi	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
CMS1_k127_305064_2	316274.Haur_1889	1.115e-32	141.0	COG0842@1|root,COG0842@2|Bacteria,2G8VC@200795|Chloroflexi	200795|Chloroflexi	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
CMS1_k127_305064_1	1304284.L21TH_0766	5.326e-93	314.0	COG3153@1|root,COG3153@2|Bacteria,1V3TY@1239|Firmicutes,25DB3@186801|Clostridia,36U94@31979|Clostridiaceae	186801|Clostridia	S	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS1_k127_305064_3	255470.cbdbA1100	5.472e-16	81.0	COG0826@1|root,COG0826@2|Bacteria,2GAVB@200795|Chloroflexi,34DF3@301297|Dehalococcoidia	301297|Dehalococcoidia	O	peptidase U32	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_305064_0	1254432.SCE1572_08670	1.595e-114	384.0	COG4826@1|root,COG4826@2|Bacteria,1REGX@1224|Proteobacteria,42T9N@68525|delta/epsilon subdivisions,2WPDB@28221|Deltaproteobacteria,2YV97@29|Myxococcales	28221|Deltaproteobacteria	O	Belongs to the serpin family	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
CMS1_k127_3064383_2	945021.TEH_22600	3.852e-66	243.0	COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,4HA89@91061|Bacilli,4AZMC@81852|Enterococcaceae	91061|Bacilli	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	GO:0003674,GO:0003824,GO:0004017,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
CMS1_k127_3064383_1	306281.AJLK01000065_gene5420	2.15e-125	412.0	COG1503@1|root,COG1503@2|Bacteria,1G29A@1117|Cyanobacteria,1JI27@1189|Stigonemataceae	1117|Cyanobacteria	J	translation release factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3064383_0	926569.ANT_01580	1.127e-154	500.0	COG0474@1|root,COG0474@2|Bacteria,2G5ZS@200795|Chloroflexi	200795|Chloroflexi	P	TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
CMS1_k127_3067134_3	448385.sce2707	5.476e-49	183.0	2E8ZQ@1|root,33397@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3067134_2	1304275.C41B8_00175	8.539e-88	298.0	COG2132@1|root,COG2132@2|Bacteria,1QUX3@1224|Proteobacteria,1S6MG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Domain of unknown function (DUF4396)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4396
CMS1_k127_3067134_1	1267533.KB906734_gene3722	2.881e-127	414.0	COG1023@1|root,COG1023@2|Bacteria,3Y2ZP@57723|Acidobacteria,2JHSA@204432|Acidobacteriia	204432|Acidobacteriia	G	6-phosphogluconate dehydrogenase (Decarboxylating)	-	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
CMS1_k127_3067134_6	138119.DSY3891	0.0001056	46.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,247RM@186801|Clostridia,260F2@186807|Peptococcaceae	186801|Clostridia	L	PFAM UvrD REP helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
CMS1_k127_3067134_0	555088.DealDRAFT_1304	2.68e-137	477.0	COG2909@1|root,COG3947@1|root,COG2909@2|Bacteria,COG3947@2|Bacteria,1UIMV@1239|Firmicutes,25GAH@186801|Clostridia	186801|Clostridia	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD
CMS1_k127_3067134_5	886293.Sinac_1104	1.05e-06	51.0	COG2128@1|root,COG2128@2|Bacteria,2IZDY@203682|Planctomycetes	203682|Planctomycetes	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS1_k127_3067134_4	269799.Gmet_2646	1.354e-07	54.0	COG2128@1|root,COG2128@2|Bacteria,1RHU7@1224|Proteobacteria,42SKU@68525|delta/epsilon subdivisions,2WT3P@28221|Deltaproteobacteria,43VXH@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS1_k127_307594_2	290318.Cvib_1043	8.753e-31	126.0	COG2738@1|root,COG2738@2|Bacteria,1FEE1@1090|Chlorobi	1090|Chlorobi	S	PFAM peptidase, membrane zinc metallopeptidase	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
CMS1_k127_307594_0	649638.Trad_0147	0.0	1317.0	COG1048@1|root,COG1048@2|Bacteria,1WIMG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acn	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
CMS1_k127_307594_1	383372.Rcas_0880	1.405e-85	292.0	COG0583@1|root,COG0583@2|Bacteria,2G910@200795|Chloroflexi,37768@32061|Chloroflexia	32061|Chloroflexia	K	PFAM regulatory protein, LysR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS1_k127_307594_3	1192034.CAP_2241	4.153e-09	61.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CARDB,F5_F8_type_C,SdrD_B
CMS1_k127_3079644_3	316274.Haur_4640	6.477e-46	169.0	COG4570@1|root,COG4570@2|Bacteria,2G8U7@200795|Chloroflexi	200795|Chloroflexi	L	Endodeoxyribonuclease RusA	-	-	3.1.22.4	ko:K01160	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	RusA
CMS1_k127_3079644_9	945713.IALB_0170	1.523e-20	97.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	MA20_14850	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
CMS1_k127_3079644_8	1449050.JNLE01000005_gene4975	5.895e-24	104.0	COG0504@1|root,COG0504@2|Bacteria,1V9C7@1239|Firmicutes,250HA@186801|Clostridia,36RPS@31979|Clostridiaceae	186801|Clostridia	F	Glutamine amidotransferase class-I	-	-	-	-	-	-	-	-	-	-	-	-	GATase
CMS1_k127_3079644_6	44251.PDUR_14340	2.254e-40	153.0	COG0504@1|root,COG0504@2|Bacteria,1V9C7@1239|Firmicutes,4HXRY@91061|Bacilli,26YIE@186822|Paenibacillaceae	91061|Bacilli	F	Glutamine amidotransferase class-I	-	-	-	-	-	-	-	-	-	-	-	-	GATase
CMS1_k127_3079644_0	243090.RB11273	4.224e-152	490.0	COG0477@1|root,COG2814@2|Bacteria,2J067@203682|Planctomycetes	203682|Planctomycetes	EGP	Major facilitator superfamily	-	-	-	ko:K07552	-	-	-	-	ko00000,ko02000	2.A.1.2	-	-	MFS_1
CMS1_k127_3079644_4	1211815.CBYP010000039_gene2596	5.538e-44	170.0	COG2306@1|root,COG2306@2|Bacteria,2GJP9@201174|Actinobacteria,4EWJZ@85013|Frankiales	201174|Actinobacteria	S	Protein of unknown function (DUF402)	-	-	-	-	-	-	-	-	-	-	-	-	DUF402
CMS1_k127_3079644_10	933115.GPDM_02315	1.255e-13	72.0	2EBVE@1|root,335UU@2|Bacteria,1VGUW@1239|Firmicutes,4HP9D@91061|Bacilli,26G69@186818|Planococcaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3079644_2	1229909.NSED_06605	6.415e-54	199.0	COG1651@1|root,arCOG02868@2157|Archaea	2157|Archaea	O	COG1651 Protein-disulfide isomerase	-	-	-	ko:K21990	-	-	-	-	ko00000	1.A.16.4	-	-	Form_Nir_trans,Thioredoxin_4
CMS1_k127_3079644_7	1296416.JACB01000042_gene1780	6.13e-40	173.0	COG2304@1|root,COG3591@1|root,COG2304@2|Bacteria,COG3591@2|Bacteria	2|Bacteria	E	Belongs to the peptidase S1B family	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	Big_2,NB-ARC,PKD,PPC,Sel1,Trypsin,Trypsin_2,VWA,VWA_2
CMS1_k127_3079644_11	7213.XP_004521881.1	0.0003601	55.0	KOG1217@1|root,KOG1217@2759|Eukaryota,38BUP@33154|Opisthokonta,3BA2W@33208|Metazoa,3CUNH@33213|Bilateria,41VHE@6656|Arthropoda,3SKFR@50557|Insecta,4510U@7147|Diptera	33208|Metazoa	T	Calcium ion binding	dp	GO:0002009,GO:0002165,GO:0003674,GO:0005198,GO:0005201,GO:0005575,GO:0005576,GO:0007275,GO:0007424,GO:0007444,GO:0007472,GO:0007475,GO:0007476,GO:0007552,GO:0007560,GO:0007591,GO:0008150,GO:0008362,GO:0008587,GO:0009653,GO:0009791,GO:0009886,GO:0009887,GO:0009888,GO:0022404,GO:0031012,GO:0032501,GO:0032502,GO:0035107,GO:0035114,GO:0035120,GO:0035220,GO:0035239,GO:0035295,GO:0040003,GO:0040005,GO:0042303,GO:0042335,GO:0044421,GO:0044719,GO:0048513,GO:0048563,GO:0048569,GO:0048707,GO:0048729,GO:0048731,GO:0048736,GO:0048737,GO:0048856,GO:0060429,GO:0060541,GO:0060562,GO:0065007,GO:0065008,GO:0090066	-	-	-	-	-	-	-	-	-	-	EGF_CA
CMS1_k127_3079644_1	1174528.JH992898_gene4662	9.899e-104	345.0	COG1526@1|root,COG1526@2|Bacteria,1G2ZE@1117|Cyanobacteria,1JIDZ@1189|Stigonemataceae	1117|Cyanobacteria	C	FdhD/NarQ family	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
CMS1_k127_3079644_5	401526.TcarDRAFT_1696	1.028e-41	160.0	COG1905@1|root,COG1905@2|Bacteria,1V737@1239|Firmicutes,4H42Q@909932|Negativicutes	909932|Negativicutes	C	Thioredoxin-like [2Fe-2S] ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	2Fe-2S_thioredx
CMS1_k127_3079644_12	401526.TcarDRAFT_1694	0.0004185	44.0	COG3411@1|root,COG3411@2|Bacteria,1V6DT@1239|Firmicutes,4H52Q@909932|Negativicutes	909932|Negativicutes	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3084362_2	1509405.GV67_08610	2.991e-58	205.0	COG0028@1|root,COG0028@2|Bacteria,1N4U6@1224|Proteobacteria,2U0I6@28211|Alphaproteobacteria,4BDDC@82115|Rhizobiaceae	28211|Alphaproteobacteria	EH	Belongs to the TPP enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS1_k127_3084362_0	1462527.CCDM010000001_gene2676	3.105e-190	606.0	COG1053@1|root,COG1053@2|Bacteria,1TPAR@1239|Firmicutes,4HAXN@91061|Bacilli,23MC4@182709|Oceanobacillus	91061|Bacilli	C	COG1053 Succinate dehydrogenase fumarate reductase, flavoprotein subunit	-	-	-	ko:K13796	-	-	-	-	ko00000	-	-	-	FAD_binding_2
CMS1_k127_3084362_1	1408473.JHXO01000002_gene3832	6.438e-93	311.0	COG4106@1|root,COG4106@2|Bacteria,4NJE5@976|Bacteroidetes	976|Bacteroidetes	S	Methyltransferase	-	-	2.1.1.144	ko:K00598	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
CMS1_k127_3084362_3	1122222.AXWR01000001_gene1944	1.043e-56	207.0	COG2084@1|root,COG2084@2|Bacteria,1WJ76@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	Domain of unknown function (DUF1932)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1932,NAD_binding_2
CMS1_k127_3095783_1	329726.AM1_0715	1.277e-73	258.0	COG1672@1|root,COG1672@2|Bacteria,1G0F4@1117|Cyanobacteria	1117|Cyanobacteria	K	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	AAA_35,CHAT,TIR_2
CMS1_k127_3095783_0	91464.S7335_5568	1.614e-79	302.0	COG1672@1|root,COG1672@2|Bacteria,1G07E@1117|Cyanobacteria	1117|Cyanobacteria	M	AAA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_35,WD40
CMS1_k127_3095783_2	511051.CSE_02410	4.963e-11	75.0	COG1361@1|root,COG3210@1|root,COG4719@1|root,COG1361@2|Bacteria,COG3210@2|Bacteria,COG4719@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11
CMS1_k127_3110633_3	867903.ThesuDRAFT_02165	5.364e-90	300.0	COG1028@1|root,COG1028@2|Bacteria,1TQZW@1239|Firmicutes,249T4@186801|Clostridia	186801|Clostridia	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS1_k127_3110633_2	745776.DGo_CA0631	5.044e-90	302.0	COG2220@1|root,COG2220@2|Bacteria	2|Bacteria	S	N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Lactamase_B_2,Lactamase_B_3
CMS1_k127_3110633_0	485913.Krac_5920	2.275e-225	705.0	COG0641@1|root,COG0641@2|Bacteria,2G74V@200795|Chloroflexi	200795|Chloroflexi	C	Iron-sulfur cluster-binding domain	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Radical_SAM,SPASM
CMS1_k127_3110633_9	1148.1653503	1.751e-15	86.0	COG2214@1|root,COG2214@2|Bacteria,1GABC@1117|Cyanobacteria	1117|Cyanobacteria	O	Heat shock protein DnaJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3110633_4	756067.MicvaDRAFT_4728	2.876e-87	323.0	COG2208@1|root,COG4191@1|root,COG2208@2|Bacteria,COG4191@2|Bacteria,1G160@1117|Cyanobacteria,1H75U@1150|Oscillatoriales	1117|Cyanobacteria	KT	Stage II sporulation protein E	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	CHASE2,HAMP,SpoIIE,dCache_1
CMS1_k127_3110633_1	926550.CLDAP_32760	2.896e-224	707.0	COG0747@1|root,COG0747@2|Bacteria,2G8RA@200795|Chloroflexi	200795|Chloroflexi	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_3110633_5	43989.cce_4998	3.651e-30	124.0	COG4113@1|root,COG4113@2|Bacteria,1G7F7@1117|Cyanobacteria	1117|Cyanobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
CMS1_k127_3110633_7	521011.Mpal_1755	1.094e-25	124.0	COG0642@1|root,COG2203@1|root,arCOG02385@1|root,arCOG02356@2157|Archaea,arCOG02385@2157|Archaea,arCOG06192@2157|Archaea,2Y7TZ@28890|Euryarchaeota,2NAUN@224756|Methanomicrobia	224756|Methanomicrobia	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,PAS_3,PAS_9,Response_reg
CMS1_k127_3110633_8	880073.Calab_1292	3.186e-17	96.0	COG2202@1|root,COG2203@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg,STAS,dCache_1
CMS1_k127_3110633_6	497965.Cyan7822_5247	1.759e-28	133.0	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,3KGDE@43988|Cyanothece	1117|Cyanobacteria	T	PAS fold-4 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Response_reg
CMS1_k127_3118848_10	1123075.AUDP01000032_gene718	1.807e-28	125.0	COG0407@1|root,COG0407@2|Bacteria,1VEQ3@1239|Firmicutes,24RQ2@186801|Clostridia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
CMS1_k127_3118848_1	697281.Mahau_0030	1.208e-170	550.0	28MXM@1|root,2ZB4M@2|Bacteria,1V0PQ@1239|Firmicutes,24ENW@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3118848_6	1487923.DP73_21445	3.131e-87	296.0	COG1410@1|root,COG1410@2|Bacteria,1VRVS@1239|Firmicutes,25EJA@186801|Clostridia,267HQ@186807|Peptococcaceae	186801|Clostridia	E	CO dehydrogenase/acetyl-CoA synthase delta subunit	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Pterin_bind
CMS1_k127_3118848_9	517418.Ctha_0216	1.731e-39	152.0	2E6U3@1|root,331DV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	RsbRD_N
CMS1_k127_3118848_5	556261.HMPREF0240_03262	6.67e-92	317.0	COG0407@1|root,COG0407@2|Bacteria,1W13C@1239|Firmicutes,24Z3X@186801|Clostridia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
CMS1_k127_3118848_2	1499967.BAYZ01000009_gene5389	4.339e-158	509.0	COG0407@1|root,COG0407@2|Bacteria	2|Bacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
CMS1_k127_3118848_4	697281.Mahau_0032	7.019e-116	385.0	COG0407@1|root,COG0407@2|Bacteria,1V5KX@1239|Firmicutes,24IAR@186801|Clostridia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
CMS1_k127_3118848_0	697281.Mahau_2281	1.71e-186	591.0	28MXM@1|root,2Z8AT@2|Bacteria,1V0XI@1239|Firmicutes,24DIS@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3118848_3	658086.HMPREF0994_03659	1.027e-123	404.0	COG0407@1|root,COG0407@2|Bacteria,1V3M9@1239|Firmicutes,25AY7@186801|Clostridia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
CMS1_k127_3118848_8	720554.Clocl_0784	9.543e-46	174.0	COG0145@1|root,COG0145@2|Bacteria,1V3GN@1239|Firmicutes,25DNJ@186801|Clostridia,3WPEF@541000|Ruminococcaceae	186801|Clostridia	EQ	Protein of unknown function (DUF1638)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1638
CMS1_k127_3118848_7	468059.AUHA01000003_gene1725	1.713e-77	267.0	COG1028@1|root,COG1028@2|Bacteria,4NGQY@976|Bacteroidetes,1IRGR@117747|Sphingobacteriia	976|Bacteroidetes	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS1_k127_3120873_0	357808.RoseRS_1142	0.0	1011.0	COG1529@1|root,COG1529@2|Bacteria,2G65D@200795|Chloroflexi,376KF@32061|Chloroflexia	32061|Chloroflexia	C	PFAM aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
CMS1_k127_3120873_1	986075.CathTA2_0688	1.121e-79	273.0	COG2820@1|root,COG2820@2|Bacteria,1TQ71@1239|Firmicutes	1239|Firmicutes	F	Phosphorylase	-	-	-	-	-	-	-	-	-	-	-	-	PNP_UDP_1
CMS1_k127_3120873_2	324602.Caur_1858	3.028e-37	142.0	COG0123@1|root,COG0123@2|Bacteria,2G89I@200795|Chloroflexi,376ST@32061|Chloroflexia	32061|Chloroflexia	BQ	PFAM histone deacetylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
CMS1_k127_3122868_3	926550.CLDAP_37130	2.082e-62	231.0	COG2197@1|root,COG3055@1|root,COG2197@2|Bacteria,COG3055@2|Bacteria,2G6NU@200795|Chloroflexi	200795|Chloroflexi	KT	Kelch repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Kelch_1,Kelch_4
CMS1_k127_3122868_1	926569.ANT_15960	2.834e-146	472.0	COG0232@1|root,COG0232@2|Bacteria,2G5VZ@200795|Chloroflexi	200795|Chloroflexi	F	PFAM metal-dependent phosphohydrolase, HD sub domain	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
CMS1_k127_3122868_5	1267534.KB906757_gene1097	8.736e-29	120.0	COG2172@1|root,COG2172@2|Bacteria	2|Bacteria	T	sigma factor antagonist activity	-	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
CMS1_k127_3122868_2	485913.Krac_10218	8.607e-93	312.0	COG0500@1|root,COG2226@2|Bacteria,2GBJR@200795|Chloroflexi	200795|Chloroflexi	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS1_k127_3122868_0	485913.Krac_10219	6.725e-246	768.0	COG1964@1|root,COG1964@2|Bacteria	2|Bacteria	Q	Radical SAM superfamily	-	-	-	ko:K06937	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
CMS1_k127_3122868_4	247633.GP2143_02469	1.44e-30	126.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RQTU@1236|Gammaproteobacteria,1J4JP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	merA	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim,SNARE_assoc
CMS1_k127_3147408_3	1313172.YM304_00360	1.506e-05	47.0	COG1404@1|root,COG1404@2|Bacteria,2GK3D@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the peptidase S8 family	sbtB	-	-	-	-	-	-	-	-	-	-	-	Big_3_5,Inhibitor_I9,PA,Peptidase_S8
CMS1_k127_3147408_2	326427.Cagg_1060	1.074e-19	96.0	2DRD4@1|root,33B9X@2|Bacteria,2G9Z1@200795|Chloroflexi,377FH@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3147408_0	1120953.AUBH01000004_gene3093	8.208e-173	554.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,464PM@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	COG1404 Subtilisin-like serine proteases	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	PKD,Peptidase_S8
CMS1_k127_3147408_1	1122138.AQUZ01000006_gene1352	1.824e-47	185.0	COG4409@1|root,COG4409@2|Bacteria,2IDDY@201174|Actinobacteria,4DSSN@85009|Propionibacteriales	201174|Actinobacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3153281_4	1396418.BATQ01000049_gene383	2.465e-82	281.0	COG1577@1|root,COG1577@2|Bacteria,46V85@74201|Verrucomicrobia	74201|Verrucomicrobia	I	mevalonate kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	GHMP_kinases_C,GHMP_kinases_N
CMS1_k127_3153281_3	525904.Tter_0206	2.982e-102	344.0	COG0395@1|root,COG0395@2|Bacteria,2NQFE@2323|unclassified Bacteria	2|Bacteria	G	Binding-protein-dependent transport system inner membrane component	gtsC	-	-	ko:K02026,ko:K17317	ko02010,map02010	M00207,M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.24,3.A.1.1.30	-	-	BPD_transp_1
CMS1_k127_3153281_5	1178537.BA1_08121	1.593e-79	276.0	COG1175@1|root,COG1175@2|Bacteria,1UVVT@1239|Firmicutes,4HCKP@91061|Bacilli,1ZQ7M@1386|Bacillus	91061|Bacilli	G	COG1175 ABC-type sugar transport systems, permease components	-	-	-	ko:K17316	ko02010,map02010	M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.24,3.A.1.1.30	-	-	BPD_transp_1
CMS1_k127_3153281_1	869210.Marky_2154	9.18e-127	419.0	COG1653@1|root,COG1653@2|Bacteria,1WI1U@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K17315	ko02010,map02010	M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.24,3.A.1.1.30	-	-	SBP_bac_1
CMS1_k127_3153281_0	1120950.KB892756_gene6656	1.017e-145	468.0	COG1312@1|root,COG1312@2|Bacteria,2H319@201174|Actinobacteria,4DS9M@85009|Propionibacteriales	201174|Actinobacteria	G	Catalyzes the dehydration of D-mannonate	uxuA	-	4.2.1.8	ko:K01686	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	UxuA
CMS1_k127_3153281_6	1122138.AQUZ01000085_gene8800	2.155e-22	106.0	COG3629@1|root,COG3629@2|Bacteria,2GM4U@201174|Actinobacteria,4DUTC@85009|Propionibacteriales	201174|Actinobacteria	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD
CMS1_k127_3153281_2	485913.Krac_2635	4.547e-111	391.0	COG0457@1|root,COG3629@1|root,COG3899@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG3899@2|Bacteria,2G871@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,TPR_12
CMS1_k127_3161900_3	349521.HCH_04915	4.529e-27	124.0	COG0823@1|root,COG5616@1|root,COG0823@2|Bacteria,COG5616@2|Bacteria,1MV09@1224|Proteobacteria,1RMCY@1236|Gammaproteobacteria,1XITW@135619|Oceanospirillales	135619|Oceanospirillales	U	Involved in the TonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
CMS1_k127_3161900_2	862965.PARA_19580	2.576e-40	160.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,1RNME@1236|Gammaproteobacteria,1Y831@135625|Pasteurellales	135625|Pasteurellales	G	and related enzymes of inositol monophosphatase family	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
CMS1_k127_3161900_1	880073.Calab_1108	1.813e-72	256.0	COG1319@1|root,COG1319@2|Bacteria,2NQUQ@2323|unclassified Bacteria	2|Bacteria	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.17.1.4	ko:K11178	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
CMS1_k127_3161900_0	880073.Calab_1107	1.945e-119	413.0	COG1529@1|root,COG1529@2|Bacteria,2NPHP@2323|unclassified Bacteria	2|Bacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	1.17.1.4	ko:K11177	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
CMS1_k127_3168491_3	1521187.JPIM01000031_gene2005	3.613e-64	231.0	COG0356@1|root,COG0356@2|Bacteria,2G6NF@200795|Chloroflexi,376W7@32061|Chloroflexia	32061|Chloroflexia	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
CMS1_k127_3168491_4	398767.Glov_3140	1.215e-06	53.0	COG5336@1|root,COG5336@2|Bacteria	2|Bacteria	C	function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex	atpI	-	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATPase_gene1
CMS1_k127_3168491_1	714313.LSA_04050	1.921e-80	279.0	COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,4HB61@91061|Bacilli,3F3U2@33958|Lactobacillaceae	91061|Bacilli	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	GO:0003674,GO:0003824,GO:0004749,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
CMS1_k127_3168491_2	316274.Haur_4612	3.489e-76	275.0	COG4753@1|root,COG4963@1|root,COG4753@2|Bacteria,COG4963@2|Bacteria,2G6CH@200795|Chloroflexi,37524@32061|Chloroflexia	32061|Chloroflexia	D	PFAM response regulator receiver	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,ParA,Response_reg
CMS1_k127_3168491_0	1304880.JAGB01000002_gene1563	5.987e-142	472.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS1_k127_3178616_4	316274.Haur_0181	7.909e-11	69.0	COG0457@1|root,COG0457@2|Bacteria	316274.Haur_0181|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3178616_0	1499967.BAYZ01000074_gene2130	2.567e-244	763.0	COG0519@1|root,COG0519@2|Bacteria,2NNRS@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	iJN746.PP_1032,iSF_1195.SF2553,iSFxv_1172.SFxv_2808,iS_1188.S2725,iYL1228.KPN_02833	GATase,GMP_synt_C,NAD_synthase
CMS1_k127_3178616_2	1499967.BAYZ01000074_gene2129	1.926e-77	263.0	COG0503@1|root,COG0503@2|Bacteria	2|Bacteria	F	purine ribonucleoside salvage	xpt	GO:0003674,GO:0003824,GO:0006139,GO:0006166,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0043094,GO:0043101,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046128,GO:0046129,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.22,2.4.2.7	ko:K00759,ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R00190,R01229,R02142,R04378	RC00063,RC00122	ko00000,ko00001,ko01000,ko04147	-	-	iYO844.BSU22070	Pribosyltran
CMS1_k127_3178616_5	324602.Caur_1958	2.759e-06	55.0	2E3MN@1|root,302XP@2|Bacteria,2G95X@200795|Chloroflexi,377TT@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3178616_1	926550.CLDAP_28680	4.694e-106	362.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	SH3_3,SH3_4
CMS1_k127_3178616_3	243274.THEMA_03180	1.704e-75	265.0	COG0747@1|root,COG0747@2|Bacteria,2GCNZ@200918|Thermotogae	200918|Thermotogae	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_3179908_2	926550.CLDAP_23390	1.944e-28	122.0	COG1807@1|root,COG1807@2|Bacteria,2G9BJ@200795|Chloroflexi	2|Bacteria	M	Protein of unknown function (DUF2723)	-	-	-	ko:K14340	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	PMT_2
CMS1_k127_3179908_1	926550.CLDAP_23390	1.376e-40	169.0	COG1807@1|root,COG1807@2|Bacteria,2G9BJ@200795|Chloroflexi	2|Bacteria	M	Protein of unknown function (DUF2723)	-	-	-	ko:K14340	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	PMT_2
CMS1_k127_3179908_3	1382306.JNIM01000001_gene2526	8.493e-23	109.0	COG0454@1|root,COG0456@2|Bacteria,2G7CX@200795|Chloroflexi	200795|Chloroflexi	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS1_k127_3179908_0	927677.ALVU02000006_gene425	1.126e-96	332.0	COG4467@1|root,COG4467@2|Bacteria,1GR8D@1117|Cyanobacteria	1117|Cyanobacteria	S	Involved in initiation control of chromosome replication	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3182820_1	1382356.JQMP01000004_gene455	1.392e-179	578.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	BNR,BNR_2,CBM_2,RicinB_lectin_2
CMS1_k127_3182820_6	1382356.JQMP01000004_gene456	2.325e-12	80.0	2EX6H@1|root,33QHE@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3182820_0	926550.CLDAP_27930	1.141e-195	622.0	COG1653@1|root,COG1653@2|Bacteria,2G6V5@200795|Chloroflexi	200795|Chloroflexi	G	extracellular solute-binding protein, family 1	-	-	-	ko:K05813	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.3	-	-	SBP_bac_8
CMS1_k127_3182820_3	926550.CLDAP_27940	6.225e-123	403.0	COG0395@1|root,COG0395@2|Bacteria,2G6H2@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02026,ko:K05815	ko02010,map02010	M00198,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.3	-	-	BPD_transp_1
CMS1_k127_3182820_2	926550.CLDAP_27950	3.065e-132	428.0	COG1175@1|root,COG1175@2|Bacteria,2G6P7@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025,ko:K05814	ko02010,map02010	M00198,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.3	-	-	BPD_transp_1
CMS1_k127_3182820_5	479434.Sthe_3414	6.413e-56	207.0	COG1708@1|root,COG1708@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEPN,NTP_transf_2,UPF0158
CMS1_k127_3182820_4	479434.Sthe_3413	4.806e-68	233.0	COG1032@1|root,COG1032@2|Bacteria,2G6ZI@200795|Chloroflexi	200795|Chloroflexi	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
CMS1_k127_3189228_4	1123242.JH636437_gene6085	1.276e-12	76.0	COG3857@1|root,COG3857@2|Bacteria,2IZEK@203682|Planctomycetes	203682|Planctomycetes	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	AAA_19,Exonuc_V_gamma,PDDEXK_1,UvrD_C
CMS1_k127_3189228_2	180332.JTGN01000003_gene1990	6.338e-17	93.0	COG0407@1|root,COG0407@2|Bacteria,1TW8J@1239|Firmicutes,24BSH@186801|Clostridia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
CMS1_k127_3189228_1	485913.Krac_11567	1.951e-36	149.0	COG0457@1|root,COG0457@2|Bacteria	485913.Krac_11567|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3189228_0	880073.Calab_3204	8.669e-69	264.0	COG1022@1|root,COG1022@2|Bacteria,2NNTM@2323|unclassified Bacteria	2|Bacteria	I	COGs COG1022 Long-chain acyl-CoA synthetase (AMP-forming)	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
CMS1_k127_3189228_3	102129.Lepto7375DRAFT_2506	1.12e-12	77.0	COG4447@1|root,COG4447@2|Bacteria,1G2KP@1117|Cyanobacteria,1H6WW@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM BNR Asp-box repeat	-	-	-	-	-	-	-	-	-	-	-	-	BNR,PSII_BNR,Sortilin-Vps10
CMS1_k127_3209854_0	1499967.BAYZ01000026_gene1558	1.02e-114	372.0	COG0376@1|root,COG0376@2|Bacteria,2NQNQ@2323|unclassified Bacteria	2|Bacteria	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
CMS1_k127_3209854_7	743719.PaelaDRAFT_4548	7.103e-12	75.0	COG0346@1|root,COG0346@2|Bacteria,1V2JX@1239|Firmicutes,4HGKN@91061|Bacilli,26X0I@186822|Paenibacillaceae	91061|Bacilli	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Aminoglyc_resit
CMS1_k127_3209854_2	697303.Thewi_1678	1.279e-93	316.0	COG0813@1|root,COG0813@2|Bacteria,1TQPG@1239|Firmicutes,248G6@186801|Clostridia,42EY8@68295|Thermoanaerobacterales	186801|Clostridia	F	TIGRFAM purine nucleoside phosphorylase	deoD	-	2.4.2.1	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
CMS1_k127_3209854_4	1123008.KB905700_gene2140	5.749e-38	156.0	COG3292@1|root,COG3292@2|Bacteria,4NI2T@976|Bacteroidetes,2FV1K@200643|Bacteroidia,22Z9F@171551|Porphyromonadaceae	976|Bacteroidetes	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	Reg_prop,YceI
CMS1_k127_3209854_3	237368.SCABRO_00511	1.845e-43	160.0	COG3093@1|root,COG3093@2|Bacteria	2|Bacteria	K	addiction module antidote protein HigA	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3,HTH_31
CMS1_k127_3209854_6	452652.KSE_37680	1.702e-12	73.0	COG3871@1|root,COG3871@2|Bacteria,2I2TZ@201174|Actinobacteria,2M57W@2063|Kitasatospora	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
CMS1_k127_3209854_1	357808.RoseRS_4253	5.399e-97	324.0	COG1028@1|root,COG1028@2|Bacteria	357808.RoseRS_4253|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_321557_2	663610.JQKO01000001_gene1031	1.501e-17	87.0	COG1028@1|root,COG2124@1|root,COG1028@2|Bacteria,COG2124@2|Bacteria,1MV75@1224|Proteobacteria,2URJB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
CMS1_k127_321557_0	1128421.JAGA01000003_gene3053	2.133e-61	233.0	COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria,2NPIU@2323|unclassified Bacteria	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_4,PAS_8,Response_reg,dCache_1
CMS1_k127_321557_3	1235279.C772_00198	1.377e-08	61.0	COG2204@1|root,COG2204@2|Bacteria,1V6R9@1239|Firmicutes,4HIXH@91061|Bacilli,26FDA@186818|Planococcaceae	91061|Bacilli	T	cheY-homologous receiver domain	spo0F	-	-	ko:K02490	ko02020,ko02024,map02020,map02024	M00485	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
CMS1_k127_321557_1	419947.MRA_3417	6.181e-36	151.0	COG1657@1|root,COG1657@2|Bacteria,2GM7H@201174|Actinobacteria	201174|Actinobacteria	I	Squalene--hopene cyclase	-	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009267,GO:0009605,GO:0009607,GO:0009975,GO:0009987,GO:0009991,GO:0010350,GO:0016101,GO:0016102,GO:0016114,GO:0016853,GO:0016872,GO:0019637,GO:0031667,GO:0031668,GO:0031669,GO:0033385,GO:0033554,GO:0035439,GO:0035440,GO:0042594,GO:0043167,GO:0043169,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071496,GO:0071704,GO:0075136,GO:1901576	5.5.1.16	ko:K17811	-	-	-	-	ko00000,ko01000	-	-	-	Prenyltrans,SQHop_cyclase_C
CMS1_k127_321566_11	1379698.RBG1_1C00001G0843	2.254e-15	85.0	COG1011@1|root,COG1011@2|Bacteria,2NQ1K@2323|unclassified Bacteria	2|Bacteria	S	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	3.1.3.5	ko:K07025,ko:K08723	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
CMS1_k127_321566_4	1122221.JHVI01000007_gene2245	1.504e-79	274.0	COG0739@1|root,COG0739@2|Bacteria,1WM9M@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CMS1_k127_321566_6	1122221.JHVI01000007_gene2245	3.75e-51	198.0	COG0739@1|root,COG0739@2|Bacteria,1WM9M@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CMS1_k127_321566_5	926569.ANT_20860	8.284e-65	226.0	COG0231@1|root,COG0231@2|Bacteria,2G6PY@200795|Chloroflexi	200795|Chloroflexi	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
CMS1_k127_321566_2	926550.CLDAP_17580	4.924e-93	325.0	COG0728@1|root,COG0728@2|Bacteria,2G5PF@200795|Chloroflexi	200795|Chloroflexi	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	-	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
CMS1_k127_321566_7	1382356.JQMP01000003_gene1675	3.376e-46	172.0	COG0615@1|root,COG0615@2|Bacteria,2G6NJ@200795|Chloroflexi,27Y9C@189775|Thermomicrobia	189775|Thermomicrobia	IM	Cytidylyltransferase-like	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like
CMS1_k127_321566_3	1128421.JAGA01000003_gene3583	2.389e-87	300.0	COG2870@1|root,COG2870@2|Bacteria,2NNUT@2323|unclassified Bacteria	2|Bacteria	M	pfkB family carbohydrate kinase	rfaE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
CMS1_k127_321566_8	1042163.BRLA_c033520	9.211e-39	156.0	COG1752@1|root,COG1752@2|Bacteria,1UUVB@1239|Firmicutes,4HDFQ@91061|Bacilli,26WHE@186822|Paenibacillaceae	91061|Bacilli	S	Patatin-like phospholipase	ylbK	GO:0003674,GO:0003824,GO:0016787	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
CMS1_k127_321566_0	997346.HMPREF9374_0033	3.573e-175	566.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HA2G@91061|Bacilli,27BBZ@186824|Thermoactinomycetaceae	91061|Bacilli	IQ	AMP-binding enzyme C-terminal domain	lcfA	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
CMS1_k127_321566_1	324602.Caur_2632	1.385e-138	450.0	COG2355@1|root,COG2355@2|Bacteria,2G5Y0@200795|Chloroflexi,375WA@32061|Chloroflexia	32061|Chloroflexia	E	PFAM peptidase M19 renal dipeptidase	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
CMS1_k127_321566_9	266117.Rxyl_2674	1.675e-38	145.0	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,4CTDV@84995|Rubrobacteria	84995|Rubrobacteria	E	Aminotransferase, class I	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
CMS1_k127_3229271_3	926550.CLDAP_39140	5.114e-117	383.0	COG0438@1|root,COG0438@2|Bacteria,2G683@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS1_k127_3229271_4	269797.Mbar_A3071	1.101e-84	297.0	COG0668@1|root,arCOG01568@2157|Archaea,2XUW2@28890|Euryarchaeota,2N9TY@224756|Methanomicrobia	224756|Methanomicrobia	M	Mechanosensitive ion channel	-	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
CMS1_k127_3229271_1	383372.Rcas_2971	5.175e-156	503.0	COG0520@1|root,COG0520@2|Bacteria,2G5W7@200795|Chloroflexi,375CE@32061|Chloroflexia	32061|Chloroflexia	E	TIGRFAM cysteine desulfurase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
CMS1_k127_3229271_9	1128421.JAGA01000003_gene3190	2.531e-18	90.0	2EM6G@1|root,33EVQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3229271_0	926569.ANT_03530	5.39e-320	999.0	COG0188@1|root,COG0188@2|Bacteria,2G5Q2@200795|Chloroflexi	200795|Chloroflexi	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
CMS1_k127_3229271_7	926550.CLDAP_41010	4.134e-39	152.0	COG0359@1|root,COG0359@2|Bacteria,2G6V2@200795|Chloroflexi	200795|Chloroflexi	J	Binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
CMS1_k127_3229271_8	1128421.JAGA01000003_gene3428	2.06e-19	97.0	COG3944@1|root,COG3944@2|Bacteria	2|Bacteria	M	capsule polysaccharide biosynthetic process	-	-	-	ko:K16692	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	GNVR,Wzz
CMS1_k127_3229271_6	926550.CLDAP_01220	8.571e-51	188.0	COG3944@1|root,COG3944@2|Bacteria,2G9GX@200795|Chloroflexi	200795|Chloroflexi	M	PFAM lipopolysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzz
CMS1_k127_3229271_5	1128421.JAGA01000003_gene3426	1.223e-60	219.0	COG0489@1|root,COG0489@2|Bacteria,2NNNP@2323|unclassified Bacteria	2|Bacteria	D	CobQ CobB MinD ParA nucleotide binding domain	-	-	2.7.10.2	ko:K08253,ko:K16554,ko:K16692	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02000	8.A.3.1	-	-	AAA_31,CbiA,GNVR,ParA,Wzz
CMS1_k127_3229271_2	926550.CLDAP_37530	6.018e-123	401.0	COG3842@1|root,COG3842@2|Bacteria,2G62V@200795|Chloroflexi	200795|Chloroflexi	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
CMS1_k127_3229466_5	929556.Solca_0685	3.153e-37	145.0	COG0681@1|root,COG0681@2|Bacteria,4NSIR@976|Bacteroidetes,1ITMV@117747|Sphingobacteriia	976|Bacteroidetes	U	Belongs to the peptidase S26 family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3229466_2	504472.Slin_3982	8.943e-126	409.0	COG3386@1|root,COG3386@2|Bacteria,4NF4A@976|Bacteroidetes,47NKG@768503|Cytophagia	976|Bacteroidetes	G	SMP-30 Gluconolaconase LRE domain protein	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
CMS1_k127_3229466_0	1303518.CCALI_02520	2.34e-176	570.0	COG0464@1|root,COG0464@2|Bacteria	2|Bacteria	O	ATPase activity	ycf46	-	3.6.4.6	ko:K06027	ko04138,ko04721,ko04727,ko04962,map04138,map04721,map04727,map04962	-	-	-	ko00000,ko00001,ko01000,ko04131	1.F.1.1	-	-	AAA
CMS1_k127_3229466_7	439235.Dalk_2289	0.0003097	53.0	COG3291@1|root,COG3391@1|root,COG3291@2|Bacteria,COG3391@2|Bacteria,1MWIT@1224|Proteobacteria,42W2M@68525|delta/epsilon subdivisions,2WRTW@28221|Deltaproteobacteria,2MKVR@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD,VCBS
CMS1_k127_3229466_6	1255043.TVNIR_1116	4.442e-05	56.0	COG3209@1|root,COG3292@1|root,COG3391@1|root,COG3209@2|Bacteria,COG3292@2|Bacteria,COG3391@2|Bacteria,1MVV1@1224|Proteobacteria,1RY7B@1236|Gammaproteobacteria,1X2AS@135613|Chromatiales	135613|Chromatiales	M	TIGRFAM RHS repeat-associated core domain	-	-	-	-	-	-	-	-	-	-	-	-	NHL,RHS_repeat
CMS1_k127_3229466_1	744980.TRICHSKD4_4032	2.687e-147	482.0	COG0006@1|root,COG0006@2|Bacteria,1MVX5@1224|Proteobacteria,2TRMK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Xaa-Pro aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Creatinase_N,Peptidase_M24
CMS1_k127_3229466_3	1095769.CAHF01000006_gene1926	1.392e-104	343.0	COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,2VIRB@28216|Betaproteobacteria,476N7@75682|Oxalobacteraceae	28216|Betaproteobacteria	L	endonuclease III	-	-	-	-	-	-	-	-	-	-	-	-	HhH-GPD
CMS1_k127_3229466_4	316067.Geob_3836	9.776e-76	262.0	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,42KZC@68525|delta/epsilon subdivisions,2WJ31@28221|Deltaproteobacteria,43TF6@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
CMS1_k127_3236255_4	1444309.JAQG01000100_gene4709	1.158e-50	192.0	COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,26QGU@186822|Paenibacillaceae	91061|Bacilli	E	ABC transporter substrate-binding protein	dppE	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
CMS1_k127_3236255_3	926550.CLDAP_14740	3.829e-73	254.0	COG0639@1|root,COG0639@2|Bacteria,2G6GC@200795|Chloroflexi	200795|Chloroflexi	T	PFAM metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
CMS1_k127_3236255_6	1521187.JPIM01000006_gene1733	1.921e-39	152.0	COG0802@1|root,COG0802@2|Bacteria,2G6YV@200795|Chloroflexi,375TA@32061|Chloroflexia	32061|Chloroflexia	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	-	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
CMS1_k127_3236255_5	1128421.JAGA01000002_gene1896	3.529e-43	165.0	COG1214@1|root,COG1214@2|Bacteria,2NPK8@2323|unclassified Bacteria	2|Bacteria	O	Glycoprotease family	yeaZ	GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564	2.3.1.234	ko:K01409,ko:K14742	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
CMS1_k127_3236255_7	203119.Cthe_1774	1.24e-33	136.0	COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,24J9Z@186801|Clostridia,3WKHF@541000|Ruminococcaceae	186801|Clostridia	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
CMS1_k127_3236255_1	1382306.JNIM01000001_gene4079	1.155e-171	554.0	COG0595@1|root,COG0595@2|Bacteria,2G611@200795|Chloroflexi	200795|Chloroflexi	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
CMS1_k127_3236255_2	1121930.AQXG01000005_gene597	5.629e-97	321.0	COG0778@1|root,COG0778@2|Bacteria,4NFJK@976|Bacteroidetes,1IUKS@117747|Sphingobacteriia	976|Bacteroidetes	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CMS1_k127_3236255_0	926550.CLDAP_31730	5.913e-182	595.0	COG1674@1|root,COG1674@2|Bacteria,2G5XC@200795|Chloroflexi	200795|Chloroflexi	D	PFAM cell divisionFtsK SpoIIIE	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
CMS1_k127_3242760_1	1323663.AROI01000002_gene1074	8.864e-06	48.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,1S25K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
CMS1_k127_3242760_0	926550.CLDAP_38470	3.659e-28	114.0	COG2141@1|root,COG2141@2|Bacteria,2G5MF@200795|Chloroflexi	200795|Chloroflexi	C	PFAM luciferase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS1_k127_325192_0	309801.trd_1603	8.62e-171	560.0	COG0550@1|root,COG0550@2|Bacteria,2G5ZR@200795|Chloroflexi,27XYG@189775|Thermomicrobia	189775|Thermomicrobia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
CMS1_k127_325192_5	383372.Rcas_0053	8.592e-15	82.0	2DRD4@1|root,33B9X@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_325192_2	926569.ANT_23030	4.786e-33	145.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	-	-	-	-	-	-	-	-	-	-	APH,Aminotran_3,Peptidase_M23
CMS1_k127_325192_3	926550.CLDAP_10530	2.585e-28	133.0	COG0457@1|root,COG0823@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,2G8PZ@200795|Chloroflexi	200795|Chloroflexi	U	WD40 domain protein beta Propeller	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
CMS1_k127_325192_4	326427.Cagg_1680	9.5e-16	92.0	COG0515@1|root,COG0515@2|Bacteria,2G9EP@200795|Chloroflexi,375W6@32061|Chloroflexia	32061|Chloroflexia	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
CMS1_k127_325192_6	1128421.JAGA01000002_gene1897	1.686e-12	81.0	COG1716@1|root,COG1716@2|Bacteria,2NQ4X@2323|unclassified Bacteria	2|Bacteria	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA,Yop-YscD_cpl
CMS1_k127_326705_1	485913.Krac_5801	3.141e-72	255.0	COG2186@1|root,COG2186@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
CMS1_k127_326705_5	1122132.AQYH01000005_gene444	4.363e-13	70.0	COG0395@1|root,COG0395@2|Bacteria,1N4I0@1224|Proteobacteria,2TT14@28211|Alphaproteobacteria,4BMAS@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_326705_8	7425.NV16111-PA	1.288e-08	64.0	KOG3948@1|root,KOG3948@2759|Eukaryota,38CJ2@33154|Opisthokonta,3BIGQ@33208|Metazoa,3D2WG@33213|Bilateria,41Z5P@6656|Arthropoda,3SMFY@50557|Insecta,46H6Z@7399|Hymenoptera	33208|Metazoa	A	PHAX RNA-binding domain	PHAX	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005813,GO:0005815,GO:0005829,GO:0005856,GO:0006139,GO:0006351,GO:0006366,GO:0006403,GO:0006405,GO:0006408,GO:0006725,GO:0006807,GO:0006810,GO:0006913,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009301,GO:0009987,GO:0010467,GO:0015630,GO:0015643,GO:0015931,GO:0016070,GO:0016073,GO:0018130,GO:0019438,GO:0031974,GO:0031981,GO:0032774,GO:0033036,GO:0034641,GO:0034645,GO:0034654,GO:0034660,GO:0036477,GO:0042795,GO:0043025,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044297,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0046907,GO:0050657,GO:0050658,GO:0051030,GO:0051168,GO:0051169,GO:0051179,GO:0051234,GO:0051236,GO:0051641,GO:0051649,GO:0070013,GO:0071702,GO:0071704,GO:0071705,GO:0090304,GO:0097064,GO:0097159,GO:0097458,GO:0097659,GO:0098781,GO:1901360,GO:1901362,GO:1901363,GO:1901576	-	ko:K14291	ko03013,map03013	-	-	-	ko00000,ko00001	-	-	-	RNA_GG_bind
CMS1_k127_326705_7	645991.Sgly_0001	1.99e-10	74.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,2490S@186801|Clostridia,260P2@186807|Peptococcaceae	186801|Clostridia	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
CMS1_k127_326705_6	926569.ANT_24330	1.145e-10	75.0	COG0593@1|root,COG0593@2|Bacteria	2|Bacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N,Y1_Tnp
CMS1_k127_326705_2	926569.ANT_24350	8.85e-65	229.0	COG1192@1|root,COG1192@2|Bacteria	2|Bacteria	D	plasmid maintenance	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
CMS1_k127_326705_4	742823.HMPREF9465_02360	5.746e-19	100.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,2VHJV@28216|Betaproteobacteria,4PQD5@995019|Sutterellaceae	28216|Betaproteobacteria	D	Ftsk_gamma	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
CMS1_k127_326705_0	1121382.JQKG01000051_gene2218	1.689e-112	377.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
CMS1_k127_326705_3	485913.Krac_4653	2.246e-38	147.0	COG1085@1|root,COG1085@2|Bacteria,2G6K5@200795|Chloroflexi	200795|Chloroflexi	H	TIGRFAM galactose-1-phosphate uridylyltransferase	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
CMS1_k127_3280087_5	926550.CLDAP_19470	7.352e-22	110.0	COG0457@1|root,COG3629@1|root,COG3903@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG3903@2|Bacteria,2G7SC@200795|Chloroflexi	200795|Chloroflexi	K	intracellular signal transduction	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12
CMS1_k127_3280087_3	485913.Krac_7924	4.885e-85	289.0	COG2318@1|root,COG2318@2|Bacteria,2G8NT@200795|Chloroflexi	200795|Chloroflexi	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
CMS1_k127_3280087_1	1237149.C900_00574	1.045e-127	415.0	COG2267@1|root,COG2267@2|Bacteria,4NF80@976|Bacteroidetes	976|Bacteroidetes	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CMS1_k127_3280087_2	479434.Sthe_1500	3.786e-108	362.0	COG0520@1|root,COG0520@2|Bacteria,2G7JU@200795|Chloroflexi,27XQN@189775|Thermomicrobia	189775|Thermomicrobia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	-	ko:K11325	-	-	-	-	ko00000	-	-	-	Aminotran_5
CMS1_k127_3280087_4	926550.CLDAP_04440	3.6e-62	219.0	COG0742@1|root,COG0742@2|Bacteria,2G6Y8@200795|Chloroflexi	200795|Chloroflexi	L	Methyltransferase	-	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
CMS1_k127_3280087_0	518766.Rmar_1683	8.025e-169	546.0	COG1501@1|root,COG1501@2|Bacteria,4NE1H@976|Bacteroidetes,1FJTJ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	Domain of unknown function (DUF5110)	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	DUF4968,DUF5110,Gal_mutarotas_2,Glyco_hydro_31
CMS1_k127_3280793_0	926550.CLDAP_23180	2.123e-194	616.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
CMS1_k127_3280793_1	926550.CLDAP_23190	3.448e-119	391.0	COG1175@1|root,COG1175@2|Bacteria,2G80Q@200795|Chloroflexi	200795|Chloroflexi	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_3280793_2	926550.CLDAP_23200	8.484e-115	379.0	COG0395@1|root,COG0395@2|Bacteria,2G7M8@200795|Chloroflexi	2|Bacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_3280793_5	1122915.AUGY01000068_gene6756	3.099e-26	123.0	COG1653@1|root,COG1653@2|Bacteria,1TRIH@1239|Firmicutes,4HA29@91061|Bacilli,274K4@186822|Paenibacillaceae	91061|Bacilli	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
CMS1_k127_3280793_4	935845.JADQ01000018_gene3806	1.303e-75	263.0	COG0395@1|root,COG0395@2|Bacteria,1UY7D@1239|Firmicutes,4HCWU@91061|Bacilli,26QC7@186822|Paenibacillaceae	91061|Bacilli	G	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02026,ko:K10242	ko02010,map02010	M00206,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.23	-	-	BPD_transp_1
CMS1_k127_3280793_3	937777.Deipe_0045	1.618e-82	285.0	COG1175@1|root,COG1175@2|Bacteria,1WJI2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_3301435_7	240016.ABIZ01000001_gene2223	5.922e-15	77.0	COG0624@1|root,COG0624@2|Bacteria,46VZE@74201|Verrucomicrobia,2IW3Z@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
CMS1_k127_3301435_4	1038867.AXAY01000023_gene4617	6.739e-63	222.0	COG0580@1|root,COG0580@2|Bacteria,1MXTJ@1224|Proteobacteria,2U13E@28211|Alphaproteobacteria,3JXB1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	Major intrinsic protein	-	-	-	-	-	-	-	-	-	-	-	-	MIP
CMS1_k127_3301435_1	760568.Desku_0627	3.423e-154	507.0	COG2414@1|root,COG2414@2|Bacteria,1TPT9@1239|Firmicutes,2481Q@186801|Clostridia,25ZZK@186807|Peptococcaceae	186801|Clostridia	C	Aldehyde ferredoxin oxidoreductase, domains 2 & 3	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
CMS1_k127_3301435_0	867845.KI911784_gene549	4.338e-293	914.0	COG0058@1|root,COG0058@2|Bacteria,2G5KG@200795|Chloroflexi,37562@32061|Chloroflexia	32061|Chloroflexia	G	PFAM glycosyl transferase, family 35	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
CMS1_k127_3301435_6	926550.CLDAP_29590	7.212e-31	132.0	28RJQ@1|root,2ZDYJ@2|Bacteria,2G9S7@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3301435_2	926550.CLDAP_09010	1.147e-95	321.0	COG0005@1|root,COG0005@2|Bacteria,2G5KQ@200795|Chloroflexi	200795|Chloroflexi	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
CMS1_k127_3301435_5	926550.CLDAP_15390	7.912e-59	211.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
CMS1_k127_3301435_3	391937.NA2_14122	3.922e-90	301.0	28K0D@1|root,2Z9QD@2|Bacteria,1Q9GC@1224|Proteobacteria,2TT16@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3301558_6	316274.Haur_3525	2.551e-24	106.0	COG0510@1|root,COG0510@2|Bacteria	2|Bacteria	M	ethanolamine kinase activity	-	-	2.7.1.89	ko:K07251,ko:K18844	ko00730,ko01100,map00730,map01100	-	R02134	RC00002,RC00017	ko00000,ko00001,ko01000,ko01504	-	-	-	APH,Choline_kinase
CMS1_k127_3301558_1	1122604.JONR01000009_gene2431	1.287e-96	322.0	COG0500@1|root,COG2226@2|Bacteria,1MXP4@1224|Proteobacteria,1S7AD@1236|Gammaproteobacteria,1X7WW@135614|Xanthomonadales	135614|Xanthomonadales	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
CMS1_k127_3301558_8	1123386.AUIW01000001_gene235	0.0004646	47.0	2DSVR@1|root,33HKS@2|Bacteria,1WKIU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	Ribbon-helix-helix protein, copG family	-	-	-	-	-	-	-	-	-	-	-	-	RHH_1,RHH_3,RHH_4
CMS1_k127_3301558_3	1174528.JH992893_gene5895	2.242e-78	269.0	COG2091@1|root,COG2091@2|Bacteria,1G5GA@1117|Cyanobacteria,1JH83@1189|Stigonemataceae	1117|Cyanobacteria	H	4'-phosphopantetheinyl transferase superfamily	-	-	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
CMS1_k127_3301558_0	926550.CLDAP_16330	2.13e-119	412.0	COG4485@1|root,COG4485@2|Bacteria,2G75F@200795|Chloroflexi	200795|Chloroflexi	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
CMS1_k127_3301558_7	926550.CLDAP_08050	7.268e-19	96.0	2EHA5@1|root,33B21@2|Bacteria,2G7H6@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NERD
CMS1_k127_3301558_2	1304284.L21TH_1395	4.216e-94	320.0	COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,247KW@186801|Clostridia,36E96@31979|Clostridiaceae	186801|Clostridia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
CMS1_k127_3301558_4	1449126.JQKL01000012_gene3514	4.365e-53	189.0	COG0343@1|root,COG0343@2|Bacteria,1TNZ4@1239|Firmicutes,247NJ@186801|Clostridia,267ZX@186813|unclassified Clostridiales	186801|Clostridia	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
CMS1_k127_330389_4	485916.Dtox_3622	1.464e-83	284.0	COG0689@1|root,COG0689@2|Bacteria,1TQM3@1239|Firmicutes,25E5P@186801|Clostridia,26123@186807|Peptococcaceae	186801|Clostridia	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56,3.6.1.66	ko:K00989,ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03016	-	-	-	Ham1p_like,RNase_PH,RNase_PH_C
CMS1_k127_330389_3	926550.CLDAP_23390	5.115e-93	329.0	COG1807@1|root,COG1807@2|Bacteria,2G9BJ@200795|Chloroflexi	2|Bacteria	M	Protein of unknown function (DUF2723)	-	-	-	ko:K14340	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	PMT_2
CMS1_k127_330389_5	357808.RoseRS_2216	7.763e-62	220.0	COG0357@1|root,COG0357@2|Bacteria,2G6HF@200795|Chloroflexi,375M8@32061|Chloroflexia	32061|Chloroflexia	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
CMS1_k127_330389_6	485913.Krac_6639	1.219e-56	208.0	COG0127@1|root,COG0127@2|Bacteria,2G6GK@200795|Chloroflexi	200795|Chloroflexi	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
CMS1_k127_330389_0	926550.CLDAP_06600	7.085e-248	775.0	COG0459@1|root,COG0459@2|Bacteria,2G65N@200795|Chloroflexi	200795|Chloroflexi	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
CMS1_k127_330389_7	926550.CLDAP_06590	3.744e-36	138.0	COG0234@1|root,COG0234@2|Bacteria,2G6WW@200795|Chloroflexi	200795|Chloroflexi	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
CMS1_k127_330389_8	1232410.KI421420_gene3150	9.67e-11	65.0	COG1826@1|root,COG1826@2|Bacteria,1NGDP@1224|Proteobacteria,42V5P@68525|delta/epsilon subdivisions,2WRM0@28221|Deltaproteobacteria,43VW0@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	mttA/Hcf106 family	-	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
CMS1_k127_330389_2	572547.Amico_1047	2.642e-125	410.0	COG1494@1|root,COG1494@2|Bacteria,3T9RI@508458|Synergistetes	508458|Synergistetes	G	TIGRFAM fructose-1,6-bisphosphatase, class II	glpX	-	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
CMS1_k127_330389_1	926550.CLDAP_16400	5.163e-166	550.0	COG3063@1|root,COG3629@1|root,COG3899@1|root,COG3063@2|Bacteria,COG3629@2|Bacteria,COG3899@2|Bacteria,2G7ZN@200795|Chloroflexi	200795|Chloroflexi	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,Trans_reg_C
CMS1_k127_3305082_4	926550.CLDAP_24710	5.683e-117	381.0	COG0647@1|root,COG0647@2|Bacteria,2G6QY@200795|Chloroflexi	200795|Chloroflexi	G	PFAM Haloacid dehalogenase domain protein hydrolase	-	-	-	ko:K02566	-	-	-	-	ko00000	-	-	-	Hydrolase_6,Hydrolase_like
CMS1_k127_3305082_7	1207063.P24_06686	1.913e-87	295.0	COG1011@1|root,COG1011@2|Bacteria,1MU1H@1224|Proteobacteria,2TQVC@28211|Alphaproteobacteria,2JRRZ@204441|Rhodospirillales	204441|Rhodospirillales	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase
CMS1_k127_3305082_1	1499967.BAYZ01000027_gene1769	2.212e-145	472.0	COG2271@1|root,COG2271@2|Bacteria	2|Bacteria	G	transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_3305082_3	1353528.DT23_08695	1.892e-133	443.0	COG3119@1|root,COG3119@2|Bacteria,1MV0B@1224|Proteobacteria,2TRI6@28211|Alphaproteobacteria,2XMP5@285107|Thioclava	28211|Alphaproteobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS1_k127_3305082_8	99598.Cal7507_4484	7.117e-60	214.0	COG5553@1|root,COG5553@2|Bacteria,1GBMH@1117|Cyanobacteria,1HS2T@1161|Nostocales	1117|Cyanobacteria	S	Cysteine dioxygenase type I	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3305082_10	935840.JAEQ01000020_gene2372	6.601e-47	184.0	COG4948@1|root,COG4948@2|Bacteria,1MXK7@1224|Proteobacteria,2TVB4@28211|Alphaproteobacteria,43PM1@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
CMS1_k127_3305082_6	1380394.JADL01000013_gene703	6.954e-89	303.0	COG0667@1|root,COG0667@2|Bacteria,1R5BH@1224|Proteobacteria,2TS0A@28211|Alphaproteobacteria,2JVHZ@204441|Rhodospirillales	204441|Rhodospirillales	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS1_k127_3305082_5	1082933.MEA186_34979	3.371e-98	333.0	COG4948@1|root,COG4948@2|Bacteria,1NCUP@1224|Proteobacteria,2U0G5@28211|Alphaproteobacteria,43R1V@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	M	Mandelate racemase muconate lactonizing enzyme	-	-	4.2.1.6	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R03033	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
CMS1_k127_3305082_12	1304883.KI912532_gene2030	3.63e-24	106.0	COG0642@1|root,COG4942@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,COG4942@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria,2KVVC@206389|Rhodocyclales	206389|Rhodocyclales	T	COG0642 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,HycI,PAS_9,Response_reg
CMS1_k127_3305082_9	42256.RradSPS_0609	2.183e-57	203.0	COG0288@1|root,COG0288@2|Bacteria,2GM1M@201174|Actinobacteria,4CSPT@84995|Rubrobacteria	84995|Rubrobacteria	P	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
CMS1_k127_3305082_2	316274.Haur_1707	4.202e-135	463.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,2G6X4@200795|Chloroflexi,37715@32061|Chloroflexia	32061|Chloroflexia	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12
CMS1_k127_3305082_11	316274.Haur_1709	9.329e-36	143.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_3305082_0	926550.CLDAP_24310	1.578e-155	497.0	COG0012@1|root,COG0012@2|Bacteria,2G5UY@200795|Chloroflexi	200795|Chloroflexi	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
CMS1_k127_3320581_1	485913.Krac_10336	9.387e-130	429.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5,DDE_Tnp_1_4
CMS1_k127_3320581_0	1122931.AUAE01000031_gene2875	1.56e-266	841.0	COG3808@1|root,COG3808@2|Bacteria,4NF2I@976|Bacteroidetes,2FM7F@200643|Bacteroidia,22WAD@171551|Porphyromonadaceae	976|Bacteroidetes	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase,OmpA
CMS1_k127_3320581_2	196490.AUEZ01000013_gene4726	1.254e-10	72.0	COG3899@1|root,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2UP80@28211|Alphaproteobacteria,3K2GY@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Adenylate Guanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3333728_3	479434.Sthe_1622	1.385e-166	537.0	COG0747@1|root,COG0747@2|Bacteria	2|Bacteria	E	dipeptide transport	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_3333728_1	1128421.JAGA01000002_gene390	2.701e-233	749.0	COG0770@1|root,COG0787@1|root,COG0770@2|Bacteria,COG0787@2|Bacteria,2NP3R@2323|unclassified Bacteria	2|Bacteria	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1,6.3.2.10	ko:K01775,ko:K01929	ko00300,ko00473,ko00550,ko01100,ko01502,map00300,map00473,map00550,map01100,map01502	-	R00401,R04573,R04617	RC00064,RC00141,RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N,Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS1_k127_3333728_15	1304885.AUEY01000012_gene1826	4.762e-25	112.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,42UQP@68525|delta/epsilon subdivisions,2WQKU@28221|Deltaproteobacteria,2MMAC@213118|Desulfobacterales	28221|Deltaproteobacteria	S	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
CMS1_k127_3333728_13	525904.Tter_0302	3.905e-38	156.0	COG1432@1|root,COG1432@2|Bacteria,2NR68@2323|unclassified Bacteria	2|Bacteria	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN
CMS1_k127_3333728_2	316274.Haur_0023	1.543e-221	719.0	COG0515@1|root,COG3087@1|root,COG0515@2|Bacteria,COG3087@2|Bacteria,2G67H@200795|Chloroflexi,374SX@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS1_k127_3333728_7	1125863.JAFN01000001_gene586	2.669e-78	285.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,42MFK@68525|delta/epsilon subdivisions,2WKBU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	extracellular solute-binding protein, family 5	-	-	-	ko:K02035,ko:K13893	ko02010,ko02024,map02010,map02024	M00239,M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
CMS1_k127_3333728_10	857293.CAAU_0436	2.716e-69	247.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,36F10@31979|Clostridiaceae	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	appB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_3333728_11	1051632.TPY_2387	5.119e-56	209.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia	186801|Clostridia	P	ABC-type dipeptide oligopeptide nickel transport	oppC	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
CMS1_k127_3333728_4	1173028.ANKO01000139_gene671	3.166e-130	427.0	COG1502@1|root,COG1502@2|Bacteria,1G01I@1117|Cyanobacteria,1H79E@1150|Oscillatoriales	2|Bacteria	I	TIGRFAM Competence protein ComEA, helix-hairpin-helix	-	-	3.1.4.4	ko:K17717	ko00564,ko00565,ko01100,ko01110,map00564,map00565,map01100,map01110	-	R01310,R02051,R07385	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	PLDc_2
CMS1_k127_3333728_16	867845.KI911784_gene3348	1.89e-21	95.0	COG0227@1|root,COG0227@2|Bacteria,2GB39@200795|Chloroflexi,377UD@32061|Chloroflexia	32061|Chloroflexia	J	PFAM ribosomal protein L28	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
CMS1_k127_3333728_12	926550.CLDAP_32750	5.507e-40	153.0	COG0735@1|root,COG0735@2|Bacteria,2G723@200795|Chloroflexi	200795|Chloroflexi	K	Belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
CMS1_k127_3333728_8	926569.ANT_03770	2.06e-77	265.0	COG1719@1|root,COG1719@2|Bacteria,2G8D0@200795|Chloroflexi	200795|Chloroflexi	S	4-vinyl reductase, 4VR	-	-	-	-	-	-	-	-	-	-	-	-	V4R
CMS1_k127_3333728_6	102125.Xen7305DRAFT_00020850	1.932e-84	291.0	COG3823@1|root,COG3823@2|Bacteria,1GPV5@1117|Cyanobacteria,3VMFK@52604|Pleurocapsales	1117|Cyanobacteria	O	Glutamine cyclotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glu_cyclase_2
CMS1_k127_3333728_9	926550.CLDAP_13920	7.714e-77	262.0	COG0299@1|root,COG0299@2|Bacteria,2G6ZJ@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
CMS1_k127_3333728_5	1121382.JQKG01000010_gene4728	1.94e-118	389.0	COG0150@1|root,COG0150@2|Bacteria,1WIP0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	F	PFAM AIR synthase related protein, N-terminal domain	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
CMS1_k127_3333728_14	1303518.CCALI_01319	3.387e-34	134.0	COG0151@1|root,COG0151@2|Bacteria	2|Bacteria	F	phosphoribosylamine-glycine ligase activity	purD	-	6.3.2.6,6.3.4.13,6.3.5.3	ko:K01945,ko:K01952,ko:K13713	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04463,R04591	RC00010,RC00064,RC00090,RC00162,RC00166,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS05245,iYO844.BSU06530	GARS_A,GARS_C,GARS_N
CMS1_k127_3335331_1	547559.Nmag_0490	0.000174	53.0	COG1403@1|root,arCOG03898@2157|Archaea,2XUHK@28890|Euryarchaeota,23TMW@183963|Halobacteria	183963|Halobacteria	V	COG1403 Restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH
CMS1_k127_3335331_0	861360.AARI_15860	2.804e-12	77.0	COG3415@1|root,COG3415@2|Bacteria,2GSX1@201174|Actinobacteria	201174|Actinobacteria	L	Protein of unknown function (DUF2637)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2637
CMS1_k127_3341949_1	1240349.ANGC01000006_gene1448	1.02e-61	220.0	COG1285@1|root,COG1285@2|Bacteria,2GM32@201174|Actinobacteria,4FW4W@85025|Nocardiaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4956)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
CMS1_k127_3341949_2	1172181.KB911761_gene1871	1.389e-52	194.0	COG5036@1|root,COG5036@2|Bacteria,2GKBU@201174|Actinobacteria	201174|Actinobacteria	P	COG5036 SPX domain-containing protein involved in vacuolar polyphosphate accumulation	-	-	-	-	-	-	-	-	-	-	-	-	VTC
CMS1_k127_3341949_0	1396141.BATP01000057_gene3053	3.468e-126	428.0	COG2312@1|root,COG3209@1|root,COG2312@2|Bacteria,COG3209@2|Bacteria,46XD5@74201|Verrucomicrobia,2IVHX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Fn3_assoc,LTD
CMS1_k127_3342525_4	1121085.AUCI01000017_gene2492	4.727e-55	201.0	COG4948@1|root,COG4948@2|Bacteria,1TS0S@1239|Firmicutes,4HC1G@91061|Bacilli,1ZB5J@1386|Bacillus	91061|Bacilli	M	Belongs to the mandelate racemase muconate lactonizing enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
CMS1_k127_3342525_7	526225.Gobs_0362	1.081e-14	86.0	COG0125@1|root,COG0125@2|Bacteria,2H78H@201174|Actinobacteria	201174|Actinobacteria	F	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3342525_0	357808.RoseRS_2371	3.797e-111	374.0	COG0438@1|root,COG0438@2|Bacteria,2G9B8@200795|Chloroflexi,376I5@32061|Chloroflexia	32061|Chloroflexia	H	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS1_k127_3342525_1	269799.Gmet_2008	9.537e-78	276.0	COG1215@1|root,COG1215@2|Bacteria,1QUFX@1224|Proteobacteria,42R2C@68525|delta/epsilon subdivisions,2WMZ7@28221|Deltaproteobacteria,43V8U@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
CMS1_k127_3342525_5	383372.Rcas_3103	6.247e-41	172.0	COG3307@1|root,COG3307@2|Bacteria,2GB55@200795|Chloroflexi,377AJ@32061|Chloroflexia	32061|Chloroflexia	M	PFAM O-antigen polymerase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
CMS1_k127_3342525_2	1380390.JIAT01000010_gene4360	1.647e-75	273.0	COG2244@1|root,COG2244@2|Bacteria,2I4II@201174|Actinobacteria,4CTZ7@84995|Rubrobacteria	84995|Rubrobacteria	S	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
CMS1_k127_3342525_6	1123508.JH636439_gene1292	6.998e-26	117.0	COG0500@1|root,COG2226@2|Bacteria,2J1F4@203682|Planctomycetes	203682|Planctomycetes	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS1_k127_3346203_3	1407650.BAUB01000001_gene159	1.656e-37	149.0	COG1075@1|root,COG1075@2|Bacteria,1G5J7@1117|Cyanobacteria,1H0HT@1129|Synechococcus	1117|Cyanobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3346203_2	448385.sce5828	2.871e-42	170.0	COG0644@1|root,COG0644@2|Bacteria,1MXQY@1224|Proteobacteria,42UR3@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	TIGRFAM geranylgeranyl reductase	-	-	1.3.1.111,1.3.1.83	ko:K10960	ko00860,ko00900,ko01100,ko01110,map00860,map00900,map01100,map01110	-	R02063,R08754,R08755,R08756,R11226,R11518	RC00212,RC00522,RC01823	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3,FAD_oxidored
CMS1_k127_3346203_1	1499967.BAYZ01000157_gene603	5.484e-51	206.0	COG2203@1|root,COG2208@1|root,COG3829@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,COG3829@2|Bacteria	2|Bacteria	T	transcription factor binding	-	-	3.1.3.3	ko:K07315,ko:K17763	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF,GAF_2,GGDEF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,STAS
CMS1_k127_3346203_0	1122179.KB890423_gene2374	1.177e-162	522.0	COG0028@1|root,COG0028@2|Bacteria,4NH3H@976|Bacteroidetes,1IPG9@117747|Sphingobacteriia	976|Bacteroidetes	EH	Belongs to the TPP enzyme family	poxB	-	1.2.5.1,2.2.1.6	ko:K00156,ko:K01652	ko00290,ko00620,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R03145,R04672,R04673,R08648	RC00027,RC00106,RC00860,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS1_k127_336049_4	118161.KB235920_gene5945	9.76e-17	88.0	COG2274@1|root,COG2274@2|Bacteria,1G1Y7@1117|Cyanobacteria,3VMKQ@52604|Pleurocapsales	1117|Cyanobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1	-	-	ABC_membrane,ABC_tran
CMS1_k127_336049_0	370438.PTH_2380	2.342e-301	941.0	COG2274@1|root,COG2274@2|Bacteria,1V77J@1239|Firmicutes,25E7C@186801|Clostridia,261EJ@186807|Peptococcaceae	186801|Clostridia	V	NHLM bacteriocin system ABC transporter, peptidase ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran,Peptidase_C39
CMS1_k127_336049_3	1173027.Mic7113_4412	6.013e-40	154.0	COG2905@1|root,COG2905@2|Bacteria,1GQ2G@1117|Cyanobacteria,1HI0B@1150|Oscillatoriales	1117|Cyanobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
CMS1_k127_336049_2	768706.Desor_3782	3.339e-53	198.0	COG0845@1|root,COG0845@2|Bacteria,1V0EP@1239|Firmicutes,24DYZ@186801|Clostridia,261KI@186807|Peptococcaceae	186801|Clostridia	M	TIGRFAM NHLM bacteriocin system secretion protein	-	-	-	ko:K02022	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
CMS1_k127_336049_1	118005.AWNK01000001_gene1885	2.687e-80	282.0	COG1404@1|root,COG2931@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	P_proprotein,Peptidase_S8,VCBS
CMS1_k127_3362438_1	706587.Desti_5628	5.148e-134	433.0	COG0601@1|root,COG0601@2|Bacteria,1NS80@1224|Proteobacteria,42N5D@68525|delta/epsilon subdivisions,2WIRR@28221|Deltaproteobacteria,2MQBC@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_3362438_0	383372.Rcas_2452	4.36e-154	496.0	COG1173@1|root,COG1173@2|Bacteria,2G7U9@200795|Chloroflexi,377XX@32061|Chloroflexia	32061|Chloroflexia	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
CMS1_k127_3362438_4	268739.Nmlp_3445	9.334e-36	145.0	COG5285@1|root,arCOG09157@2157|Archaea,2XTXQ@28890|Euryarchaeota,23V37@183963|Halobacteria	183963|Halobacteria	Q	COG5285 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
CMS1_k127_3362438_3	266117.Rxyl_0770	1.95e-81	290.0	COG3119@1|root,COG3119@2|Bacteria,2H50Z@201174|Actinobacteria,4CRT6@84995|Rubrobacteria	84995|Rubrobacteria	P	PFAM sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS1_k127_3362438_2	926569.ANT_30280	5.398e-95	320.0	COG0667@1|root,COG0667@2|Bacteria,2G631@200795|Chloroflexi	200795|Chloroflexi	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS1_k127_3362438_6	670487.Ocepr_0414	3.453e-05	46.0	COG2377@1|root,COG2377@2|Bacteria,1WI56@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
CMS1_k127_3362921_0	1499967.BAYZ01000095_gene4145	7.466e-118	391.0	COG0210@1|root,COG1379@1|root,COG0210@2|Bacteria,COG1379@2|Bacteria,2NNW8@2323|unclassified Bacteria	2|Bacteria	L	DNA helicase	yqxK	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DUF4178,PHP_C,UvrD-helicase,UvrD_C
CMS1_k127_3362921_3	324057.Pjdr2_1174	3.714e-34	145.0	COG0673@1|root,COG0673@2|Bacteria,1TP83@1239|Firmicutes,4HUZ7@91061|Bacilli,26RDG@186822|Paenibacillaceae	91061|Bacilli	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_3362921_1	485913.Krac_6780	4.054e-104	347.0	COG2141@1|root,COG2141@2|Bacteria,2G87P@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Luciferase-like	-	-	1.14.14.5	ko:K04091	ko00920,map00920	-	R07210,R10206	RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	Bac_luciferase
CMS1_k127_3362921_2	1194972.MVAC_12718	2.069e-57	204.0	COG0662@1|root,COG0662@2|Bacteria,2I41N@201174|Actinobacteria,2380V@1762|Mycobacteriaceae	201174|Actinobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS1_k127_3362921_4	391625.PPSIR1_09715	3.986e-25	111.0	COG3386@1|root,COG3386@2|Bacteria,1P3IB@1224|Proteobacteria,43CN0@68525|delta/epsilon subdivisions,2X7V7@28221|Deltaproteobacteria,2Z22T@29|Myxococcales	28221|Deltaproteobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3415518_8	43989.cce_0149	2.389e-10	66.0	COG0631@1|root,COG0631@2|Bacteria,1FZZK@1117|Cyanobacteria,3KGJY@43988|Cyanothece	1117|Cyanobacteria	T	SMART protein phosphatase 2C domain protein	-	-	3.1.3.16	ko:K01090	-	-	-	-	ko00000,ko01000	-	-	-	DZR,PP2C_2
CMS1_k127_3415518_5	671143.DAMO_2937	1.444e-49	187.0	COG0784@1|root,COG3290@1|root,COG3829@1|root,COG4191@1|root,COG0784@2|Bacteria,COG3290@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,2NS4C@2323|unclassified Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,SPOB_a
CMS1_k127_3415518_6	1128421.JAGA01000002_gene1090	6.207e-32	126.0	2BZBR@1|root,32YH6@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
CMS1_k127_3415518_4	861299.J421_5981	5.352e-50	205.0	COG0642@1|root,COG2205@2|Bacteria,1ZTAI@142182|Gemmatimonadetes	861299.J421_5981|-	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3415518_2	1173028.ANKO01000170_gene3354	1.156e-52	214.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1H8C9@1150|Oscillatoriales	1117|Cyanobacteria	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_4,Response_reg
CMS1_k127_3415518_7	552811.Dehly_1139	3.964e-24	120.0	COG4585@1|root,COG4585@2|Bacteria,2G8Y6@200795|Chloroflexi,34CZ4@301297|Dehalococcoidia	301297|Dehalococcoidia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS
CMS1_k127_3415518_1	1128421.JAGA01000003_gene3270	8.646e-58	208.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K07669	ko02020,map02020	M00460	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
CMS1_k127_3415518_3	1128421.JAGA01000003_gene3270	1.819e-52	192.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K07669	ko02020,map02020	M00460	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
CMS1_k127_3415518_0	452637.Oter_3899	5.401e-210	671.0	COG0471@1|root,COG3273@1|root,COG0471@2|Bacteria,COG3273@2|Bacteria,46UA9@74201|Verrucomicrobia,3K7MZ@414999|Opitutae	414999|Opitutae	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,Na_sulph_symp,TrkA_C
CMS1_k127_3424551_6	944435.AXAJ01000001_gene696	6.295e-07	55.0	COG3618@1|root,COG3618@2|Bacteria,1R4T9@1224|Proteobacteria	1224|Proteobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CMS1_k127_3424551_3	211165.AJLN01000015_gene2327	2.249e-55	202.0	COG0500@1|root,COG2226@2|Bacteria,1GCN5@1117|Cyanobacteria	1117|Cyanobacteria	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
CMS1_k127_3424551_2	395019.Bmul_4186	3.571e-69	256.0	COG4409@1|root,COG4409@2|Bacteria,1Q513@1224|Proteobacteria,2WB3C@28216|Betaproteobacteria,1K536@119060|Burkholderiaceae	28216|Betaproteobacteria	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR,BNR_2
CMS1_k127_3424551_4	985255.APHJ01000024_gene1172	6.13e-18	99.0	COG3391@1|root,COG3391@2|Bacteria,4NK97@976|Bacteroidetes,1HYP5@117743|Flavobacteriia,2P7C8@244698|Gillisia	976|Bacteroidetes	M	HYR domain	-	-	-	-	-	-	-	-	-	-	-	-	HYR
CMS1_k127_3424551_7	660470.Theba_0221	1.147e-05	59.0	COG1470@1|root,COG1470@2|Bacteria	2|Bacteria	S	cell adhesion involved in biofilm formation	yerB	-	-	-	-	-	-	-	-	-	-	-	DUF3048,DUF3048_C
CMS1_k127_3424551_1	743719.PaelaDRAFT_0995	1.535e-76	270.0	COG2334@1|root,COG2334@2|Bacteria,1TSRC@1239|Firmicutes,4HEJ3@91061|Bacilli,26SKV@186822|Paenibacillaceae	91061|Bacilli	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS1_k127_3424551_0	324602.Caur_2965	5.432e-82	281.0	COG1806@1|root,COG1806@2|Bacteria,2G8E0@200795|Chloroflexi	200795|Chloroflexi	S	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation	-	-	2.7.11.33,2.7.4.28	ko:K09773	-	-	-	-	ko00000,ko01000	-	-	-	Kinase-PPPase
CMS1_k127_3424551_5	391625.PPSIR1_06376	2.263e-09	64.0	COG5276@1|root,COG5276@2|Bacteria,1RBM1@1224|Proteobacteria,42TF9@68525|delta/epsilon subdivisions,2WPX5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
CMS1_k127_3431093_1	1521187.JPIM01000004_gene3090	5.559e-123	402.0	COG0714@1|root,COG0714@2|Bacteria,2G5WI@200795|Chloroflexi,37710@32061|Chloroflexia	32061|Chloroflexia	S	PFAM ATPase associated with various cellular activities, AAA_5	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
CMS1_k127_3431093_0	1521187.JPIM01000158_gene1703	3.101e-124	409.0	COG3552@1|root,COG3552@2|Bacteria,2G5IW@200795|Chloroflexi,3769V@32061|Chloroflexia	32061|Chloroflexia	S	SMART von Willebrand factor, type A	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
CMS1_k127_3431093_3	479434.Sthe_1403	2.341e-37	143.0	COG1975@1|root,COG1975@2|Bacteria,2G6Z8@200795|Chloroflexi,27YDJ@189775|Thermomicrobia	189775|Thermomicrobia	O	XdhC and CoxI family	-	-	-	-	-	-	-	-	-	-	-	-	XdhC_CoxI
CMS1_k127_3431093_2	926550.CLDAP_00260	3.498e-78	271.0	COG1975@1|root,COG1975@2|Bacteria,2G6H0@200795|Chloroflexi	200795|Chloroflexi	O	XdhC Rossmann domain	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
CMS1_k127_3431093_4	326427.Cagg_1398	8.91e-19	87.0	COG0303@1|root,COG0303@2|Bacteria,2G99Q@200795|Chloroflexi,3772N@32061|Chloroflexia	32061|Chloroflexia	H	PFAM molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
CMS1_k127_3438484_4	59196.RICGR_0859	0.0007044	46.0	COG1357@1|root,COG2948@1|root,COG1357@2|Bacteria,COG2948@2|Bacteria,1N3WV@1224|Proteobacteria,1S91W@1236|Gammaproteobacteria,1JCWA@118969|Legionellales	118969|Legionellales	U	Bacterial conjugation TrbI-like protein	icmE	-	-	ko:K12209	-	-	-	-	ko00000,ko02044	3.A.7.9.1	-	-	Pentapeptide_4,TrbI
CMS1_k127_3438484_1	96561.Dole_2350	7.57e-72	246.0	COG1628@1|root,COG1628@2|Bacteria,1RCX1@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function DUF99	-	-	-	ko:K09120	-	-	-	-	ko00000	-	-	-	DUF99
CMS1_k127_3438484_0	1237500.ANBA01000009_gene1044	6.986e-126	415.0	COG3214@1|root,COG3214@2|Bacteria,2GJM7@201174|Actinobacteria,4EGXC@85012|Streptosporangiales	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
CMS1_k127_3438484_3	1278073.MYSTI_05554	2.195e-49	183.0	COG1280@1|root,COG1280@2|Bacteria,1MWA1@1224|Proteobacteria,42TJI@68525|delta/epsilon subdivisions,2WQM5@28221|Deltaproteobacteria,2Z313@29|Myxococcales	28221|Deltaproteobacteria	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
CMS1_k127_3438484_2	926550.CLDAP_26800	6.806e-53	194.0	2E65M@1|root,330UB@2|Bacteria,2G8DC@200795|Chloroflexi	200795|Chloroflexi	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
CMS1_k127_3494432_3	1223410.KN050846_gene2423	1.512e-30	126.0	COG2159@1|root,COG2159@2|Bacteria,4NK6T@976|Bacteroidetes,1I2BN@117743|Flavobacteriia	976|Bacteroidetes	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CMS1_k127_3494432_0	604331.AUHY01000002_gene1192	7.528e-184	586.0	COG0624@1|root,COG0624@2|Bacteria,1WIRQ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	PFAM Peptidase family M20 M25 M40	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
CMS1_k127_3494432_2	485913.Krac_7459	4.117e-40	163.0	COG3178@1|root,COG3178@2|Bacteria	2|Bacteria	S	peptidoglycan turnover	-	-	-	-	-	-	-	-	-	-	-	-	APH,Choline_kinase
CMS1_k127_3494432_1	1211815.CBYP010000063_gene1857	3.982e-47	184.0	COG3173@1|root,COG3173@2|Bacteria,2GMZQ@201174|Actinobacteria,4EXAK@85013|Frankiales	201174|Actinobacteria	S	Ecdysteroid kinase	-	-	-	-	-	-	-	-	-	-	-	-	APH,EcKinase
CMS1_k127_3494432_4	485913.Krac_7459	4.667e-16	86.0	COG3178@1|root,COG3178@2|Bacteria	2|Bacteria	S	peptidoglycan turnover	-	-	-	-	-	-	-	-	-	-	-	-	APH,Choline_kinase
CMS1_k127_352523_9	313624.NSP_52640	1.376e-17	93.0	COG0642@1|root,COG0745@1|root,COG2203@1|root,COG5278@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG5278@2|Bacteria,1G09B@1117|Cyanobacteria,1HMEM@1161|Nostocales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF,GAF_2,HATPase_c,HisKA,Hpt,PAS_4,PAS_9,Response_reg
CMS1_k127_352523_8	926550.CLDAP_03540	1.519e-24	114.0	COG0642@1|root,COG0784@1|root,COG2203@1|root,COG0784@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,2G7J9@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,Hpt,PAS,PAS_4,Response_reg
CMS1_k127_352523_3	525904.Tter_0922	3.332e-64	228.0	COG2120@1|root,COG2120@2|Bacteria,2NPAV@2323|unclassified Bacteria	2|Bacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
CMS1_k127_352523_7	665956.HMPREF1032_03738	1.015e-33	140.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS1_k127_352523_0	383372.Rcas_2464	2.595e-146	471.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_352523_2	1385511.N783_18520	6.033e-95	325.0	2B730@1|root,3203X@2|Bacteria,1U9S6@1239|Firmicutes,4IJYR@91061|Bacilli,2YB89@289201|Pontibacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_352523_10	661478.OP10G_0131	1.681e-05	48.0	COG1961@1|root,COG1961@2|Bacteria	2|Bacteria	L	recombinase activity	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
CMS1_k127_352523_5	1303518.CCALI_00704	2.153e-49	193.0	COG0642@1|root,COG2205@2|Bacteria	1303518.CCALI_00704|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_352523_1	926569.ANT_15930	6.7e-96	324.0	COG0382@1|root,COG0382@2|Bacteria,2G5WY@200795|Chloroflexi	200795|Chloroflexi	H	PFAM UbiA prenyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	UbiA
CMS1_k127_352523_6	926550.CLDAP_03790	4.677e-41	155.0	COG0103@1|root,COG0103@2|Bacteria,2G6UZ@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
CMS1_k127_352523_4	292459.STH3041	2.993e-62	216.0	COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,24HD9@186801|Clostridia	186801|Clostridia	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
CMS1_k127_352523_11	1410612.JNKO01000004_gene1474	3.723e-05	46.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,248W2@186801|Clostridia,2PRH7@265975|Oribacterium	186801|Clostridia	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
CMS1_k127_3525236_3	1121422.AUMW01000018_gene1918	3.531e-141	474.0	COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,247ZA@186801|Clostridia,260VD@186807|Peptococcaceae	186801|Clostridia	L	TIGRFAM ATP-dependent DNA helicase, RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
CMS1_k127_3525236_5	1128421.JAGA01000002_gene1664	3.145e-104	347.0	COG1446@1|root,COG1446@2|Bacteria,2NPFC@2323|unclassified Bacteria	2|Bacteria	E	Asparaginase	asnA2	GO:0005575,GO:0005623,GO:0042597,GO:0044464	3.4.19.5,3.5.1.1,3.5.1.26	ko:K01424,ko:K01444,ko:K13051	ko00250,ko00460,ko00511,ko01100,ko01110,ko04142,map00250,map00460,map00511,map01100,map01110,map04142	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000,ko01002	-	-	-	Asparaginase_2
CMS1_k127_3525236_10	1156844.KB891803_gene2484	2.357e-88	305.0	COG1404@1|root,COG1404@2|Bacteria,2GK3D@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_S8
CMS1_k127_3525236_7	926569.ANT_23640	1.699e-93	336.0	COG2114@1|root,COG2203@1|root,COG5002@1|root,COG2114@2|Bacteria,COG2203@2|Bacteria,COG5002@2|Bacteria,2G6X8@200795|Chloroflexi	200795|Chloroflexi	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,GAF_2,GAF_3,Guanylate_cyc,PAS
CMS1_k127_3525236_23	926559.JoomaDRAFT_2880	3.026e-23	108.0	COG1011@1|root,COG1011@2|Bacteria,4NM66@976|Bacteroidetes,1I188@117743|Flavobacteriia	976|Bacteroidetes	S	haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E	yjjG	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
CMS1_k127_3525236_25	1207063.P24_17558	0.0001018	47.0	COG1961@1|root,COG1961@2|Bacteria,1PWCY@1224|Proteobacteria,2TVME@28211|Alphaproteobacteria,2JW58@204441|Rhodospirillales	204441|Rhodospirillales	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Resolvase
CMS1_k127_3525236_12	926569.ANT_07490	2.118e-81	280.0	COG0600@1|root,COG0600@2|Bacteria,2G6HW@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
CMS1_k127_3525236_11	926569.ANT_07480	1.64e-85	295.0	COG0715@1|root,COG0715@2|Bacteria,2G6E9@200795|Chloroflexi	200795|Chloroflexi	P	PFAM NMT1 THI5 like domain protein	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
CMS1_k127_3525236_13	1380394.JADL01000001_gene2547	4.452e-80	274.0	COG1116@1|root,COG1116@2|Bacteria,1MUIM@1224|Proteobacteria,2TRHM@28211|Alphaproteobacteria,2JW7Z@204441|Rhodospirillales	204441|Rhodospirillales	P	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
CMS1_k127_3525236_1	1173027.Mic7113_4717	1.804e-145	468.0	COG1397@1|root,COG1397@2|Bacteria,1G437@1117|Cyanobacteria,1H9KV@1150|Oscillatoriales	1117|Cyanobacteria	O	ADP-ribosylglycohydrolase	-	-	3.2.2.24	ko:K05521	-	-	-	-	ko00000,ko01000	-	-	-	ADP_ribosyl_GH
CMS1_k127_3525236_15	1173029.JH980292_gene1360	7.742e-73	255.0	COG3568@1|root,COG3568@2|Bacteria,1G3B1@1117|Cyanobacteria,1H937@1150|Oscillatoriales	1117|Cyanobacteria	L	Metal-dependent hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CMS1_k127_3525236_16	243164.DET0571	4.403e-68	248.0	COG0308@1|root,COG0308@2|Bacteria,2G6SD@200795|Chloroflexi,34D27@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Peptidase MA superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2
CMS1_k127_3525236_17	311424.DhcVS_510	4.41e-65	242.0	COG0308@1|root,COG0308@2|Bacteria,2G6SD@200795|Chloroflexi,34D27@301297|Dehalococcoidia	301297|Dehalococcoidia	E	Peptidase MA superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2
CMS1_k127_3525236_9	926550.CLDAP_41100	3.81e-90	307.0	COG0052@1|root,COG0052@2|Bacteria,2G5J2@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
CMS1_k127_3525236_14	431943.CKL_1418	1.659e-74	260.0	COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,36DEJ@31979|Clostridiaceae	186801|Clostridia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
CMS1_k127_3525236_6	926550.CLDAP_41120	4.042e-95	316.0	COG0528@1|root,COG0528@2|Bacteria,2G5RG@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
CMS1_k127_3525236_19	926569.ANT_03510	1.578e-59	211.0	COG0233@1|root,COG0233@2|Bacteria,2G6FY@200795|Chloroflexi	200795|Chloroflexi	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
CMS1_k127_3525236_8	926550.CLDAP_41140	7.734e-93	310.0	COG0020@1|root,COG0020@2|Bacteria,2G65C@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
CMS1_k127_3525236_0	324602.Caur_2312	2.064e-154	494.0	COG1088@1|root,COG1088@2|Bacteria,2G5KR@200795|Chloroflexi,375GP@32061|Chloroflexia	32061|Chloroflexia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
CMS1_k127_3525236_20	926550.CLDAP_40550	9.667e-52	195.0	COG0652@1|root,COG0652@2|Bacteria,2G8IA@200795|Chloroflexi	200795|Chloroflexi	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	Pro_isomerase,Thioredoxin_4
CMS1_k127_3525236_22	696747.NIES39_G01080	5.605e-37	154.0	COG1376@1|root,COG1376@2|Bacteria,1G4ZS@1117|Cyanobacteria,1HAVT@1150|Oscillatoriales	1117|Cyanobacteria	S	ErfK YbiS YcfS YnhG	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
CMS1_k127_3525236_21	224719.Abm4_0226	3.965e-39	158.0	COG1208@1|root,arCOG00668@2157|Archaea,2Y87C@28890|Euryarchaeota,23PZH@183925|Methanobacteria	183925|Methanobacteria	M	Nucleotidyl transferase	-	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
CMS1_k127_3525236_18	479434.Sthe_1712	6.694e-64	233.0	COG0859@1|root,COG0859@2|Bacteria,2G8MX@200795|Chloroflexi,27Y5X@189775|Thermomicrobia	189775|Thermomicrobia	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
CMS1_k127_3525236_4	926569.ANT_11210	2.333e-122	399.0	COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria,2G64T@200795|Chloroflexi	200795|Chloroflexi	E	Formiminotransferase domain, N-terminal subdomain	-	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD,FTCD_C,FTCD_N
CMS1_k127_3525236_2	1487953.JMKF01000011_gene5929	1.31e-143	462.0	COG2189@1|root,COG2189@2|Bacteria,1G2XK@1117|Cyanobacteria,1HA14@1150|Oscillatoriales	1117|Cyanobacteria	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
CMS1_k127_3533689_1	1385935.N836_10600	1.182e-102	342.0	COG0668@1|root,COG0668@2|Bacteria,1G06A@1117|Cyanobacteria	1117|Cyanobacteria	M	COG0668 Small-conductance mechanosensitive channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
CMS1_k127_3533689_0	324602.Caur_3785	4.616e-108	362.0	COG0438@1|root,COG0438@2|Bacteria,2G60E@200795|Chloroflexi,376AW@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
CMS1_k127_3533689_4	926569.ANT_08580	2.8e-54	219.0	COG2199@1|root,COG2203@1|root,COG3850@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,COG3850@2|Bacteria,2G87Y@200795|Chloroflexi	200795|Chloroflexi	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF,HisKA_7TM,PAS_4,PAS_8
CMS1_k127_3533689_5	1415779.JOMH01000001_gene2895	1.151e-32	148.0	COG4585@1|root,COG4585@2|Bacteria,1MWPN@1224|Proteobacteria,1RYA9@1236|Gammaproteobacteria,1X3H8@135614|Xanthomonadales	135614|Xanthomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS,PAS_4,PAS_8,PAS_9
CMS1_k127_3533689_3	1382306.JNIM01000001_gene1045	4.96e-61	217.0	COG2197@1|root,COG2197@2|Bacteria,2G6PA@200795|Chloroflexi	200795|Chloroflexi	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS1_k127_3533689_2	383372.Rcas_3108	3.822e-79	271.0	COG2148@1|root,COG2148@2|Bacteria,2G66B@200795|Chloroflexi,376EB@32061|Chloroflexia	32061|Chloroflexia	M	PFAM sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
CMS1_k127_35346_9	309803.CTN_0069	3.662e-24	107.0	COG0834@1|root,COG0834@2|Bacteria,2GC3G@200918|Thermotogae	200918|Thermotogae	ET	PFAM extracellular solute-binding protein, family 3	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
CMS1_k127_35346_13	113355.CM001775_gene2001	1.237e-15	81.0	COG4634@1|root,COG4634@2|Bacteria,1GA41@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_35346_10	118161.KB235922_gene1736	2.689e-22	98.0	COG2442@1|root,COG2442@2|Bacteria,1G838@1117|Cyanobacteria,3VN24@52604|Pleurocapsales	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
CMS1_k127_35346_1	926550.CLDAP_01880	2.624e-145	469.0	COG3664@1|root,COG3664@2|Bacteria,2G82D@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycoside hydrolase family 39	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_35346_11	1499689.CCNN01000007_gene810	4.235e-20	94.0	COG0454@1|root,COG0456@2|Bacteria,1U2JC@1239|Firmicutes,24K69@186801|Clostridia,36K06@31979|Clostridiaceae	186801|Clostridia	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS1_k127_35346_4	926550.CLDAP_14670	4.999e-85	301.0	COG3103@1|root,COG4991@2|Bacteria,2G8KJ@200795|Chloroflexi	200795|Chloroflexi	T	Glycosyltransferase WbsX	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_99
CMS1_k127_35346_12	1449335.JQLG01000004_gene2176	1.748e-16	93.0	COG0726@1|root,COG1388@1|root,COG0726@2|Bacteria,COG1388@2|Bacteria,1UZ7Q@1239|Firmicutes,4IPRX@91061|Bacilli,27FRM@186828|Carnobacteriaceae	91061|Bacilli	GM	Polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	LysM,Polysacc_deac_1
CMS1_k127_35346_5	869210.Marky_1831	7.568e-64	223.0	COG0529@1|root,COG0529@2|Bacteria,1WK0X@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Catalyzes the synthesis of activated sulfate	cysC	-	2.7.1.25	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R04928	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
CMS1_k127_35346_7	1288963.ADIS_3437	4.379e-62	224.0	COG0454@1|root,COG0456@2|Bacteria,4NT7Q@976|Bacteroidetes,47VTT@768503|Cytophagia	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
CMS1_k127_35346_2	1122919.KB905594_gene4239	2.262e-124	407.0	COG0451@1|root,COG0451@2|Bacteria,1TPHV@1239|Firmicutes,4HCJR@91061|Bacilli,26SNR@186822|Paenibacillaceae	91061|Bacilli	GM	epimerase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
CMS1_k127_35346_6	641524.ADICYQ_5494	2.173e-63	224.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL,Lipase_GDSL_2
CMS1_k127_35346_0	998674.ATTE01000001_gene2980	4.988e-146	473.0	COG0673@1|root,COG0673@2|Bacteria,1PFCP@1224|Proteobacteria,1RRTX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_35346_3	926550.CLDAP_22360	2.026e-107	362.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_35346_8	926550.CLDAP_19470	3.987e-61	228.0	COG0457@1|root,COG3629@1|root,COG3903@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG3903@2|Bacteria,2G7SC@200795|Chloroflexi	200795|Chloroflexi	K	intracellular signal transduction	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12
CMS1_k127_3592915_4	1366050.N234_08905	1.811e-128	437.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2VH8J@28216|Betaproteobacteria,1KBP7@119060|Burkholderiaceae	28216|Betaproteobacteria	P	E1-E2 ATPase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase,YHS
CMS1_k127_3592915_6	608538.HTH_0156	2.9e-79	290.0	COG1148@1|root,COG1290@1|root,COG1908@1|root,COG1148@2|Bacteria,COG1290@2|Bacteria,COG1908@2|Bacteria	2|Bacteria	C	Methyl-viologen-reducing hydrogenase, delta subunit	napF	-	-	ko:K02572,ko:K02573,ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	CCG,Cytochrome_B,FAD_binding_6,Fer2,Fer4,Fer4_4,Fer4_5,Fer4_7,FlpD,NAD_binding_1
CMS1_k127_3592915_0	237368.SCABRO_01048	5e-322	1013.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,2J293@203682|Planctomycetes	203682|Planctomycetes	I	CoA enzyme activase uncharacterised domain (DUF2229)	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
CMS1_k127_3592915_5	765420.OSCT_2155	1.052e-91	316.0	COG3581@1|root,COG3581@2|Bacteria	2|Bacteria	I	4 iron, 4 sulfur cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
CMS1_k127_3592915_3	926550.CLDAP_04360	8.19e-193	611.0	COG1158@1|root,COG1158@2|Bacteria,2G5UQ@200795|Chloroflexi	200795|Chloroflexi	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
CMS1_k127_3592915_7	479434.Sthe_2099	8.363e-33	140.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	hcf136	-	-	-	-	-	-	-	-	-	-	-	BNR
CMS1_k127_3592915_1	926550.CLDAP_29410	4.675e-231	738.0	COG0855@1|root,COG0855@2|Bacteria,2G68J@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
CMS1_k127_3592915_9	479435.Kfla_1082	3.247e-30	134.0	COG3173@1|root,COG3173@2|Bacteria	2|Bacteria	S	very-long-chain-acyl-CoA dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS1_k127_3592915_8	700598.Niako_1749	2.431e-30	129.0	COG3828@1|root,COG3828@2|Bacteria,4NRZF@976|Bacteroidetes,1IVGZ@117747|Sphingobacteriia	976|Bacteroidetes	S	Trehalose utilisation	-	-	-	ko:K09992	-	-	-	-	ko00000	-	-	-	ThuA
CMS1_k127_3592915_2	234267.Acid_1992	1.662e-205	661.0	COG1680@1|root,COG1680@2|Bacteria,3Y8A8@57723|Acidobacteria	57723|Acidobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS1_k127_3592915_10	485913.Krac_5027	2.581e-28	126.0	COG2909@1|root,COG3903@1|root,COG2909@2|Bacteria,COG3903@2|Bacteria,2G7SC@200795|Chloroflexi	200795|Chloroflexi	K	intracellular signal transduction	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12
CMS1_k127_3594903_0	933262.AXAM01000016_gene150	8.938e-114	373.0	COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,42MFD@68525|delta/epsilon subdivisions,2WJCZ@28221|Deltaproteobacteria,2MI2F@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Sir2 family	-	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
CMS1_k127_3594903_2	926550.CLDAP_13190	1.374e-39	152.0	COG0295@1|root,COG0295@2|Bacteria,2G7AW@200795|Chloroflexi	200795|Chloroflexi	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
CMS1_k127_3594903_1	926550.CLDAP_22140	5.055e-60	217.0	COG1381@1|root,COG1381@2|Bacteria,2G6N7@200795|Chloroflexi	200795|Chloroflexi	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
CMS1_k127_3594903_3	858215.Thexy_1760	1.019e-21	102.0	COG1669@1|root,COG1669@2|Bacteria,1V8YJ@1239|Firmicutes,25DTZ@186801|Clostridia,42GH8@68295|Thermoanaerobacterales	186801|Clostridia	L	Nucleotidyltransferase domain	-	-	-	ko:K07076	-	-	-	-	ko00000	-	-	-	NTP_transf_2
CMS1_k127_3594903_4	1304284.L21TH_1851	0.0003834	46.0	COG2445@1|root,COG2445@2|Bacteria,1VF87@1239|Firmicutes,24HS2@186801|Clostridia,36IYH@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
CMS1_k127_3597864_4	323261.Noc_0230	2.379e-65	235.0	COG3055@1|root,COG3055@2|Bacteria,1QSB4@1224|Proteobacteria,1S2EP@1236|Gammaproteobacteria,1WZIK@135613|Chromatiales	135613|Chromatiales	S	Galactose oxidase, central domain	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_6
CMS1_k127_3597864_3	370438.PTH_2894	1.371e-82	282.0	COG1028@1|root,COG1028@2|Bacteria,1TPZ8@1239|Firmicutes,24903@186801|Clostridia,261ZB@186807|Peptococcaceae	186801|Clostridia	IQ	PFAM short chain dehydrogenase	kduD	-	1.1.1.127,1.1.1.304,1.1.1.69,1.1.1.76	ko:K00046,ko:K00065,ko:K18009	ko00040,ko00650,map00040,map00650	-	R01542,R03707,R09078,R10505	RC00089,RC00205,RC00525	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
CMS1_k127_3597864_6	698761.RTCIAT899_CH05055	1.152e-14	81.0	COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,2TRC2@28211|Alphaproteobacteria,4B9J8@82115|Rhizobiaceae	28211|Alphaproteobacteria	I	carboxylase	MA20_30205	-	6.4.1.4	ko:K01968	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
CMS1_k127_3597864_1	926550.CLDAP_21360	2.714e-190	608.0	COG0439@1|root,COG0439@2|Bacteria,2G62X@200795|Chloroflexi	200795|Chloroflexi	I	Carbamoyl-phosphate synthetase large chain domain protein	accC	-	6.3.4.14,6.4.1.2,6.4.1.3,6.4.1.4	ko:K01961,ko:K01968,ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00036,M00082,M00376,M00741	R00742,R01859,R04138,R04385	RC00040,RC00097,RC00253,RC00367,RC00609,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
CMS1_k127_3597864_5	102125.Xen7305DRAFT_00050480	2.439e-27	127.0	COG3540@1|root,COG3540@2|Bacteria,1GBVB@1117|Cyanobacteria	1117|Cyanobacteria	P	PhoD-like phosphatase	-	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD
CMS1_k127_3597864_2	1487953.JMKF01000063_gene4767	1.02e-100	334.0	COG1024@1|root,COG1024@2|Bacteria	2|Bacteria	I	Enoyl-CoA hydratase	MA20_16935	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
CMS1_k127_3597864_0	1128421.JAGA01000003_gene3234	4.871e-194	634.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,2NQSS@2323|unclassified Bacteria	2|Bacteria	S	Putative glutamine amidotransferase	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,GATase1_like,VWA,VWA_2,VWA_3
CMS1_k127_3601156_4	446468.Ndas_5255	2.179e-100	336.0	COG0747@1|root,COG0747@2|Bacteria,2GMV3@201174|Actinobacteria	201174|Actinobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_3601156_2	649638.Trad_1852	1.282e-147	474.0	COG0601@1|root,COG0601@2|Bacteria,1WJ61@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EP	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_3601156_0	649638.Trad_1851	1.048e-155	505.0	COG1173@1|root,COG1173@2|Bacteria,1WJDE@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EP	COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
CMS1_k127_3601156_3	649638.Trad_1850	1.718e-131	428.0	COG0444@1|root,COG0444@2|Bacteria,1WJ07@1297|Deinococcus-Thermus	2|Bacteria	P	TIGRFAM oligopeptide dipeptide ABC transporter, ATP-binding protein, C-terminal domain	oppD	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
CMS1_k127_3601156_1	649638.Trad_1849	1.727e-154	494.0	COG4608@1|root,COG4608@2|Bacteria,1WI6F@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
CMS1_k127_3601156_5	1297742.A176_04969	5.869e-80	279.0	COG0604@1|root,COG0604@2|Bacteria,1MU4N@1224|Proteobacteria,42YT7@68525|delta/epsilon subdivisions,2WUAS@28221|Deltaproteobacteria,2YTZ1@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
CMS1_k127_3605430_0	767817.Desgi_2846	5.024e-232	743.0	COG2274@1|root,COG2274@2|Bacteria,1TRMR@1239|Firmicutes,248Z2@186801|Clostridia,261E8@186807|Peptococcaceae	186801|Clostridia	P	NHLM bacteriocin system ABC transporter, ATP-binding protein	-	-	-	ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1	-	-	ABC_membrane,ABC_tran
CMS1_k127_3605430_5	485913.Krac_1241	5.934e-62	224.0	COG2141@1|root,COG2141@2|Bacteria	2|Bacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS1_k127_3605430_3	383372.Rcas_0608	2.105e-95	323.0	COG1052@1|root,COG1052@2|Bacteria,2G7VK@200795|Chloroflexi,377YP@32061|Chloroflexia	32061|Chloroflexia	C	PFAM D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
CMS1_k127_3605430_4	1356854.N007_16950	1.127e-80	281.0	COG0673@1|root,COG0673@2|Bacteria,1V157@1239|Firmicutes,4HF8V@91061|Bacilli,27AQ5@186823|Alicyclobacillaceae	91061|Bacilli	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_3605430_6	926560.KE387023_gene2599	1.787e-58	215.0	COG0395@1|root,COG0395@2|Bacteria,1WIW4@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_3605430_7	864069.MicloDRAFT_00034900	1.121e-48	186.0	COG1175@1|root,COG1175@2|Bacteria,1MVAP@1224|Proteobacteria,2TSNP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	COG1175 ABC-type sugar transport systems permease components	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
CMS1_k127_3605430_8	1122915.AUGY01000013_gene2827	3.487e-18	98.0	COG1653@1|root,COG1653@2|Bacteria,1TRAX@1239|Firmicutes,4HF9Z@91061|Bacilli,26TGU@186822|Paenibacillaceae	91061|Bacilli	G	ABC transporter substrate-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
CMS1_k127_3605430_2	1122135.KB893157_gene333	3.533e-107	360.0	COG4948@1|root,COG4948@2|Bacteria,1MURK@1224|Proteobacteria,2TRS9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Belongs to the mandelate racemase muconate lactonizing enzyme family	dgoD	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
CMS1_k127_3605430_1	42256.RradSPS_0636	2.113e-144	468.0	COG1454@1|root,COG1454@2|Bacteria,2I2FD@201174|Actinobacteria,4CQA4@84995|Rubrobacteria	201174|Actinobacteria	C	COG COG1454 Alcohol dehydrogenase class IV Energy production and conversion	-	-	1.1.1.1,1.1.1.202	ko:K00086,ko:K11440	ko00260,ko00561,ko00640,ko01100,map00260,map00561,map00640,map01100	M00555	R02377,R03119,R08557,R08558	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	Fe-ADH
CMS1_k127_3606296_4	1120934.KB894406_gene5946	0.000404	47.0	COG5485@1|root,COG5485@2|Bacteria,2HPCD@201174|Actinobacteria,4E7AW@85010|Pseudonocardiales	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
CMS1_k127_3606296_2	1121861.KB899918_gene3243	3.237e-11	64.0	COG4948@1|root,COG4948@2|Bacteria,1MXK7@1224|Proteobacteria,2TVB4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	mandelate racemase muconate lactonizing	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
CMS1_k127_3606296_0	290397.Adeh_1998	8.403e-79	287.0	COG4585@1|root,COG4585@2|Bacteria,1N0JE@1224|Proteobacteria,42UG3@68525|delta/epsilon subdivisions,2WQFT@28221|Deltaproteobacteria,2Z1DF@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA_3
CMS1_k127_3606296_1	1382306.JNIM01000001_gene1045	6.33e-72	249.0	COG2197@1|root,COG2197@2|Bacteria,2G6PA@200795|Chloroflexi	200795|Chloroflexi	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS1_k127_3606296_3	472759.Nhal_3658	3.266e-05	55.0	COG2863@1|root,COG2863@2|Bacteria,1NGKI@1224|Proteobacteria,1SI6Q@1236|Gammaproteobacteria,1X21E@135613|Chromatiales	135613|Chromatiales	C	PFAM Cytochrome c, class I	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
CMS1_k127_3609901_3	324602.Caur_3820	7.633e-143	489.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2G7SC@200795|Chloroflexi	200795|Chloroflexi	K	intracellular signal transduction	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12
CMS1_k127_3609901_7	5011.R4X863	1.491e-33	135.0	COG2343@1|root,2S7JC@2759|Eukaryota,3A0KH@33154|Opisthokonta,3Q3DM@4751|Fungi,3RKF4@4890|Ascomycota	4751|Fungi	S	Domain of unknown function (DUF427)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
CMS1_k127_3609901_0	309801.trd_1549	1.887e-290	905.0	COG0556@1|root,COG0556@2|Bacteria,2G5SU@200795|Chloroflexi,27XME@189775|Thermomicrobia	189775|Thermomicrobia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
CMS1_k127_3609901_8	436308.Nmar_1658	6.963e-33	133.0	COG1651@1|root,arCOG02868@2157|Archaea	2157|Archaea	O	COG1651 Protein-disulfide isomerase	-	-	-	ko:K21990	-	-	-	-	ko00000	1.A.16.4	-	-	Form_Nir_trans,Thioredoxin_4
CMS1_k127_3609901_1	926550.CLDAP_20900	1.024e-231	727.0	COG1012@1|root,COG1012@2|Bacteria,2G61H@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
CMS1_k127_3609901_4	1206744.BAGL01000033_gene220	6.471e-119	389.0	COG1788@1|root,COG1788@2|Bacteria,2I9F6@201174|Actinobacteria,4FZB8@85025|Nocardiaceae	201174|Actinobacteria	I	Coenzyme A transferase	catI	-	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
CMS1_k127_3609901_6	555088.DealDRAFT_2723	1.298e-67	247.0	COG0438@1|root,COG0438@2|Bacteria,1TPTA@1239|Firmicutes,24ANI@186801|Clostridia,42JHF@68298|Syntrophomonadaceae	186801|Clostridia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS1_k127_3609901_2	926550.CLDAP_28320	1.392e-173	563.0	COG0699@1|root,COG0699@2|Bacteria,2G5JQ@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Dynamin family protein	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
CMS1_k127_3609901_5	552811.Dehly_0249	6.24e-118	400.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2G5Y8@200795|Chloroflexi,34D4S@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
CMS1_k127_3613256_0	926550.CLDAP_19470	2.139e-126	443.0	COG0457@1|root,COG3629@1|root,COG3903@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG3903@2|Bacteria,2G7SC@200795|Chloroflexi	200795|Chloroflexi	K	intracellular signal transduction	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12
CMS1_k127_3622792_12	357808.RoseRS_0517	4.905e-17	82.0	COG0636@1|root,COG0636@2|Bacteria,2G72D@200795|Chloroflexi,375Z2@32061|Chloroflexia	32061|Chloroflexia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
CMS1_k127_3622792_10	696281.Desru_3692	1.979e-18	91.0	COG0711@1|root,COG0711@2|Bacteria,1VB85@1239|Firmicutes,24RWR@186801|Clostridia,261QU@186807|Peptococcaceae	186801|Clostridia	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iHN637.CLJU_RS01170	ATP-synt_B
CMS1_k127_3622792_11	1122216.AUHW01000015_gene1985	1.523e-17	89.0	COG0712@1|root,COG0712@2|Bacteria,1VAG3@1239|Firmicutes,4H4CM@909932|Negativicutes	909932|Negativicutes	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
CMS1_k127_3622792_1	926550.CLDAP_05070	2.427e-210	664.0	COG0056@1|root,COG0056@2|Bacteria,2G5YQ@200795|Chloroflexi	200795|Chloroflexi	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
CMS1_k127_3622792_5	525904.Tter_0064	8.919e-81	278.0	COG0224@1|root,COG0224@2|Bacteria,2NP76@2323|unclassified Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iLJ478.TM1611,iSSON_1240.SSON_3886,iYL1228.KPN_04138	ATP-synt
CMS1_k127_3622792_0	479434.Sthe_1421	2.148e-233	728.0	COG0055@1|root,COG0055@2|Bacteria,2G5JI@200795|Chloroflexi,27XYE@189775|Thermomicrobia	189775|Thermomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
CMS1_k127_3622792_9	552811.Dehly_0552	1.244e-33	134.0	COG0355@1|root,COG0355@2|Bacteria,2G70H@200795|Chloroflexi,34DAK@301297|Dehalococcoidia	301297|Dehalococcoidia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
CMS1_k127_3622792_2	357808.RoseRS_0510	2.358e-123	404.0	COG1077@1|root,COG1077@2|Bacteria,2G5KV@200795|Chloroflexi,374UP@32061|Chloroflexia	32061|Chloroflexia	D	TIGRFAM cell shape determining protein, MreB Mrl family	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
CMS1_k127_3622792_7	926569.ANT_13820	9.466e-67	233.0	COG2344@1|root,COG2344@2|Bacteria,2G6EJ@200795|Chloroflexi	200795|Chloroflexi	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
CMS1_k127_3622792_13	1047013.AQSP01000057_gene1924	4.681e-06	57.0	2A6YD@1|root,30VTC@2|Bacteria,2NQ0X@2323|unclassified Bacteria	2|Bacteria	S	Yip1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Yip1
CMS1_k127_3622792_8	383372.Rcas_1203	1.713e-42	174.0	COG0845@1|root,COG0845@2|Bacteria,2G6RK@200795|Chloroflexi,376DC@32061|Chloroflexia	32061|Chloroflexia	MV	TIGRFAM efflux transporter, RND family, MFP subunit	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23
CMS1_k127_3622792_4	926550.CLDAP_19390	6.196e-99	328.0	COG1136@1|root,COG1136@2|Bacteria,2G69N@200795|Chloroflexi	200795|Chloroflexi	P	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_3622792_3	401526.TcarDRAFT_0461	1.007e-113	380.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,4H2H6@909932|Negativicutes	909932|Negativicutes	V	Efflux ABC transporter permease protein	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
CMS1_k127_3622792_6	485913.Krac_0910	1.528e-79	272.0	COG2936@1|root,COG2936@2|Bacteria	2|Bacteria	V	dipeptidyl-peptidase activity	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
CMS1_k127_3623259_0	1499967.BAYZ01000084_gene3993	1.562e-169	539.0	COG1384@1|root,COG1384@2|Bacteria	2|Bacteria	J	tRNA binding	lysS	-	6.1.1.6	ko:K04566	ko00970,map00970	M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1f
CMS1_k127_3623259_2	1123065.ATWL01000009_gene973	4.34e-16	81.0	COG1308@1|root,COG1308@2|Bacteria,2GVBU@201174|Actinobacteria	201174|Actinobacteria	K	Domain of unknown function (DUF4342)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4342
CMS1_k127_3623259_1	1324957.K933_13938	3.443e-142	465.0	COG1473@1|root,arCOG01108@2157|Archaea,2XUUS@28890|Euryarchaeota,23T5A@183963|Halobacteria	183963|Halobacteria	S	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase	-	-	-	ko:K12941	-	-	-	-	ko00000,ko01002	-	-	-	M20_dimer,Peptidase_M20
CMS1_k127_3627701_8	1211817.CCAT010000083_gene1406	4.682e-10	72.0	COG1361@1|root,COG1361@2|Bacteria,1UQ5B@1239|Firmicutes,24AUI@186801|Clostridia	186801|Clostridia	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF3794
CMS1_k127_3627701_0	321846.PS417_16430	1.182e-151	489.0	COG1804@1|root,COG1804@2|Bacteria,1MW1H@1224|Proteobacteria,1RN9B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	carnitine dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
CMS1_k127_3627701_3	485913.Krac_0820	9.563e-50	190.0	COG2390@1|root,COG2390@2|Bacteria	2|Bacteria	K	carbohydrate binding	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,HTH_24,HTH_3,KR,Ketoacyl-synt_C,PP-binding,PS-DH,Sigma70_r4,Sugar-bind,ketoacyl-synt
CMS1_k127_3627701_2	575540.Isop_1614	8.055e-53	214.0	COG2373@1|root,COG2373@2|Bacteria,2IZBV@203682|Planctomycetes	203682|Planctomycetes	Q	aggregation factor core protein MAFp3, isoform C	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,FG-GAP_2
CMS1_k127_3627701_7	593750.Metfor_1389	3.008e-10	74.0	COG1994@1|root,COG3291@1|root,arCOG00614@2157|Archaea,arCOG02510@2157|Archaea,2Y7RP@28890|Euryarchaeota,2NBKZ@224756|Methanomicrobia	224756|Methanomicrobia	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD
CMS1_k127_3627701_1	945713.IALB_1503	2.661e-62	226.0	COG0618@1|root,COG0618@2|Bacteria	2|Bacteria	S	phosphoesterase RecJ domain protein	nrnA	GO:0008150,GO:0040007	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
CMS1_k127_3627701_4	1120973.AQXL01000121_gene31	7.149e-39	151.0	COG0494@1|root,COG0494@2|Bacteria,1V6F5@1239|Firmicutes,4HII9@91061|Bacilli,278E4@186823|Alicyclobacillaceae	91061|Bacilli	L	NUDIX domain	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	iSB619.SA_RS07540,iYO844.BSU23610	NUDIX
CMS1_k127_3627701_6	483219.LILAB_09475	9.141e-16	79.0	COG1388@1|root,COG3179@1|root,COG1388@2|Bacteria,COG3179@2|Bacteria,1MYUR@1224|Proteobacteria,42UGP@68525|delta/epsilon subdivisions,2WWB8@28221|Deltaproteobacteria,2YZ5E@29|Myxococcales	28221|Deltaproteobacteria	M	Chitinase class I	-	-	-	ko:K03791	-	-	-	-	ko00000	-	GH19	-	Glyco_hydro_19,LysM,PG_binding_1
CMS1_k127_3630582_3	525904.Tter_2317	1.293e-13	75.0	COG0395@1|root,COG0395@2|Bacteria	2|Bacteria	P	glycerophosphodiester transmembrane transport	-	-	-	ko:K02026,ko:K05815	ko02010,map02010	M00198,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.3	-	-	BPD_transp_1
CMS1_k127_3630582_1	926550.CLDAP_17940	7.711e-155	494.0	COG1175@1|root,COG1175@2|Bacteria,2G6TJ@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_3630582_0	926550.CLDAP_17930	7.778e-186	591.0	COG1653@1|root,COG1653@2|Bacteria,2G8HD@200795|Chloroflexi	200795|Chloroflexi	G	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
CMS1_k127_3630582_2	906968.Trebr_0130	9.951e-36	137.0	COG4154@1|root,COG4154@2|Bacteria,2J8CF@203691|Spirochaetes	203691|Spirochaetes	G	Belongs to the RbsD FucU family	-	-	5.1.3.29	ko:K02431	-	-	R10764	RC00563	ko00000,ko01000	-	-	-	RbsD_FucU
CMS1_k127_36328_3	485913.Krac_4803	1.213e-23	103.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
CMS1_k127_36328_0	266117.Rxyl_2944	8.629e-132	433.0	COG0644@1|root,COG0644@2|Bacteria,2GJDF@201174|Actinobacteria,4CQKV@84995|Rubrobacteria	84995|Rubrobacteria	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
CMS1_k127_36328_1	335543.Sfum_2526	1.043e-100	338.0	COG1163@1|root,COG1163@2|Bacteria,1RFPD@1224|Proteobacteria,42ZF3@68525|delta/epsilon subdivisions,2WUZY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TGS domain	-	-	-	ko:K06944	-	-	-	-	ko00000	-	-	-	MMR_HSR1,TGS
CMS1_k127_36328_2	221288.JH992901_gene2820	1.976e-65	228.0	COG1247@1|root,COG1247@2|Bacteria	2|Bacteria	M	phosphinothricin N-acetyltransferase activity	-	-	-	ko:K03825	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_4
CMS1_k127_36328_4	319003.Bra1253DRAFT_04194	9.347e-17	87.0	COG1514@1|root,COG1514@2|Bacteria,1RF2Z@1224|Proteobacteria,2U8SN@28211|Alphaproteobacteria,3JZ35@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	J	2'-5' RNA ligase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
CMS1_k127_36328_6	1968.JOEV01000002_gene7306	0.0006524	42.0	COG1878@1|root,COG1878@2|Bacteria,2GJ59@201174|Actinobacteria	201174|Actinobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
CMS1_k127_36328_5	1267535.KB906767_gene3429	0.0002306	49.0	COG5485@1|root,COG5485@2|Bacteria	2|Bacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
CMS1_k127_3634250_0	1120950.KB892780_gene389	5.355e-315	1005.0	COG0178@1|root,COG0178@2|Bacteria,2GJUV@201174|Actinobacteria,4DN4J@85009|Propionibacteriales	2|Bacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
CMS1_k127_3634250_5	755731.Clo1100_2799	8.464e-13	74.0	COG0494@1|root,COG0535@1|root,COG0494@2|Bacteria,COG0535@2|Bacteria,1TR52@1239|Firmicutes,247SB@186801|Clostridia,36E8H@31979|Clostridiaceae	186801|Clostridia	C	Radical SAM domain protein	-	-	-	ko:K06139	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,NUDIX,PqqD,Radical_SAM,SPASM
CMS1_k127_3634250_3	1120950.KB892739_gene3901	1.81e-43	166.0	COG2227@1|root,COG2227@2|Bacteria,2GM1S@201174|Actinobacteria,4DVQQ@85009|Propionibacteriales	201174|Actinobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS1_k127_3634250_4	216596.pRL120655	1.226e-13	74.0	2DRQB@1|root,33CKR@2|Bacteria,1MZI3@1224|Proteobacteria,2UDVN@28211|Alphaproteobacteria,4BFEI@82115|Rhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3634250_1	1499967.BAYZ01000061_gene5931	1.235e-157	503.0	COG0366@1|root,COG0366@2|Bacteria,2NP2D@2323|unclassified Bacteria	2|Bacteria	G	Alpha amylase, catalytic domain	nplT	-	3.2.1.133,3.2.1.135,3.2.1.54	ko:K01208	ko00500,ko01100,map00500,map01100	-	R02112,R03122,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459,Malt_amylase_C
CMS1_k127_3639496_3	243164.DET1603	2.702e-30	123.0	COG0294@1|root,COG0294@2|Bacteria,2G6A6@200795|Chloroflexi,34D72@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Pterin binding enzyme	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
CMS1_k127_3639496_2	1128421.JAGA01000002_gene1167	4.217e-46	171.0	COG0801@1|root,COG0801@2|Bacteria,2NPPF@2323|unclassified Bacteria	2|Bacteria	H	7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	folK	-	2.7.6.3,4.1.2.25	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503,R03504	RC00002,RC00017,RC00721,RC00943	ko00000,ko00001,ko00002,ko01000	-	-	iLJ478.TM0041	FolB,HPPK
CMS1_k127_3639496_1	1123242.JH636435_gene2640	2.944e-78	269.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	MA20_16785	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3639496_4	118173.KB235914_gene2547	2.371e-18	86.0	COG1476@1|root,COG1476@2|Bacteria,1GFFE@1117|Cyanobacteria,1HG93@1150|Oscillatoriales	1117|Cyanobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
CMS1_k127_3639496_0	1219084.AP014508_gene187	3.164e-82	279.0	COG0329@1|root,COG0329@2|Bacteria,2GC68@200918|Thermotogae	2|Bacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
CMS1_k127_3646828_0	1120959.ATXF01000011_gene340	2.226e-123	404.0	COG0578@1|root,COG0578@2|Bacteria,2GJKN@201174|Actinobacteria,4FKEP@85023|Microbacteriaceae	201174|Actinobacteria	C	C-terminal domain of alpha-glycerophosphate oxidase	glpD	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
CMS1_k127_3646828_1	357808.RoseRS_4210	1.944e-15	88.0	COG5485@1|root,COG5485@2|Bacteria,2G7DA@200795|Chloroflexi,377RA@32061|Chloroflexia	32061|Chloroflexia	P	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
CMS1_k127_3650305_3	698761.RTCIAT899_CH10245	4.458e-28	116.0	COG2220@1|root,COG2220@2|Bacteria,1MVP2@1224|Proteobacteria,2U2W2@28211|Alphaproteobacteria,4BAGJ@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
CMS1_k127_3650305_2	556261.HMPREF0240_00531	2.949e-95	324.0	COG0407@1|root,COG0407@2|Bacteria,1V4WM@1239|Firmicutes,24IZV@186801|Clostridia	186801|Clostridia	H	PFAM Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
CMS1_k127_3650305_0	926550.CLDAP_24510	1.359e-271	887.0	COG2273@1|root,COG2273@2|Bacteria,2G7RY@200795|Chloroflexi	200795|Chloroflexi	G	Glycoside hydrolase family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
CMS1_k127_3650305_1	1121378.KB899721_gene287	3.469e-209	663.0	COG1472@1|root,COG1472@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 3 family	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	CBM_6,CHB_HEX_C_1,CarboxypepD_reg,DUF5011,Fn3-like,Glyco_hydro_3,Glyco_hydro_30,Glyco_hydro_30C,Glyco_hydro_3_C,SLH
CMS1_k127_3651539_0	926550.CLDAP_38450	0.0	1102.0	COG0653@1|root,COG0653@2|Bacteria,2G603@200795|Chloroflexi	200795|Chloroflexi	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
CMS1_k127_3651539_4	65093.PCC7418_2195	6.15e-42	157.0	COG2402@1|root,COG2402@2|Bacteria,1G7M2@1117|Cyanobacteria	1117|Cyanobacteria	S	COGs COG2402 nucleic acid-binding protein contains PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
CMS1_k127_3651539_6	555778.Hneap_1999	1.913e-11	69.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,1RM9M@1236|Gammaproteobacteria,1WWZC@135613|Chromatiales	135613|Chromatiales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
CMS1_k127_3651539_7	66874.JOFS01000035_gene607	1.26e-05	52.0	COG4292@1|root,COG4292@2|Bacteria,2IC48@201174|Actinobacteria	201174|Actinobacteria	S	Bacterial low temperature requirement A protein (LtrA)	-	-	-	-	-	-	-	-	-	-	-	-	LtrA
CMS1_k127_3651539_3	118173.KB235914_gene1667	7.76e-64	229.0	COG4292@1|root,COG4292@2|Bacteria,1GBJ3@1117|Cyanobacteria,1HES6@1150|Oscillatoriales	1117|Cyanobacteria	S	Bacterial low temperature requirement A protein (LtrA)	-	-	-	-	-	-	-	-	-	-	-	-	LtrA
CMS1_k127_3651539_1	694427.Palpr_1669	1.989e-104	351.0	COG1028@1|root,COG1028@2|Bacteria,4NHSE@976|Bacteroidetes,2G33D@200643|Bacteroidia	976|Bacteroidetes	IQ	Oxidoreductase, short chain dehydrogenase reductase family protein	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS1_k127_3651539_2	485913.Krac_3313	8.049e-77	265.0	COG1028@1|root,COG1028@2|Bacteria,2G660@200795|Chloroflexi	200795|Chloroflexi	IQ	COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS1_k127_3652330_1	765420.OSCT_1808	4.249e-43	162.0	COG2010@1|root,COG2010@2|Bacteria,2G6R3@200795|Chloroflexi,377DZ@32061|Chloroflexia	32061|Chloroflexia	C	Haem-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Haem_bd
CMS1_k127_3652330_0	926569.ANT_29790	9.023e-62	220.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	-	ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
CMS1_k127_3652330_2	1231241.Mc24_03348	1.571e-14	80.0	COG0745@1|root,COG0745@2|Bacteria,2GCK6@200918|Thermotogae	200918|Thermotogae	K	PFAM response regulator receiver	-	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_3656823_0	1128421.JAGA01000003_gene3086	1.756e-292	909.0	COG0443@1|root,COG0443@2|Bacteria,2NNU1@2323|unclassified Bacteria	2|Bacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
CMS1_k127_3656823_5	331678.Cphamn1_1168	4.196e-66	233.0	COG2738@1|root,COG2738@2|Bacteria	2|Bacteria	S	Putative neutral zinc metallopeptidase	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
CMS1_k127_3656823_3	383372.Rcas_1750	5.549e-91	315.0	COG0265@1|root,COG0265@2|Bacteria,2G6KG@200795|Chloroflexi,3768V@32061|Chloroflexia	32061|Chloroflexia	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	1.3.1.74	ko:K08070	-	-	-	-	ko00000,ko01000	-	-	-	PDZ_2,Trypsin_2
CMS1_k127_3656823_4	656519.Halsa_0388	6.064e-72	249.0	COG1435@1|root,COG1435@2|Bacteria,1TRVM@1239|Firmicutes,24CVH@186801|Clostridia,3WAPX@53433|Halanaerobiales	186801|Clostridia	F	PFAM Thymidine kinase	tdk	-	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TK
CMS1_k127_3656823_11	926569.ANT_25140	4.556e-36	142.0	COG0202@1|root,COG0254@1|root,COG0202@2|Bacteria,COG0254@2|Bacteria,2G75A@200795|Chloroflexi	200795|Chloroflexi	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
CMS1_k127_3656823_12	990073.ATHU01000001_gene736	2.968e-33	130.0	COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,42THK@68525|delta/epsilon subdivisions,2YQ0A@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
CMS1_k127_3656823_13	1284686.HMPREF1630_09120	3.689e-29	121.0	COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,24MRS@186801|Clostridia,22HNF@1570339|Peptoniphilaceae	186801|Clostridia	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
CMS1_k127_3656823_7	926569.ANT_22530	3.586e-37	148.0	COG5011@1|root,COG5011@2|Bacteria,2G71I@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterized protein conserved in bacteria (DUF2344)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344
CMS1_k127_3656823_1	926550.CLDAP_37620	7.438e-243	766.0	COG1032@1|root,COG1032@2|Bacteria,2G5N0@200795|Chloroflexi	200795|Chloroflexi	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
CMS1_k127_3656823_8	391603.FBALC1_08228	1.409e-36	149.0	COG0524@1|root,COG0524@2|Bacteria	2|Bacteria	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	-	-	2.7.1.15,2.7.1.20,2.7.1.213,2.7.1.218,2.7.1.73	ko:K00852,ko:K00856,ko:K10710,ko:K22026	ko00030,ko00230,ko00240,ko01100,map00030,map00230,map00240,map01100	-	R00185,R00513,R01051,R01131,R01228,R02750,R08124	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
CMS1_k127_3656823_6	926550.CLDAP_12510	6.614e-64	229.0	COG0613@1|root,COG0613@2|Bacteria,2G6H4@200795|Chloroflexi	200795|Chloroflexi	S	SMART phosphoesterase PHP domain protein	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
CMS1_k127_3656823_9	1128427.KB904821_gene3309	2.473e-36	141.0	COG3118@1|root,COG3118@2|Bacteria,1G6KZ@1117|Cyanobacteria,1HBSI@1150|Oscillatoriales	1117|Cyanobacteria	O	Belongs to the thioredoxin family	trxA	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
CMS1_k127_3656823_10	926569.ANT_14000	3.266e-36	145.0	COG1933@1|root,COG1933@2|Bacteria	2|Bacteria	L	exodeoxyribonuclease I activity	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DZR,PLDc_N,zf-ribbon_3,zinc_ribbon_2
CMS1_k127_3656823_2	316274.Haur_3756	2.285e-188	603.0	COG0445@1|root,COG0445@2|Bacteria,2G629@200795|Chloroflexi,376CM@32061|Chloroflexia	32061|Chloroflexia	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
CMS1_k127_3658572_0	926569.ANT_26570	3.325e-127	416.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.7.13.3	ko:K10819	-	-	-	-	ko00000,ko01000	-	-	-	HAMP,HATPase_c,HisKA
CMS1_k127_3658572_3	926569.ANT_26560	1.6e-99	330.0	COG0745@1|root,COG0745@2|Bacteria,2G8EK@200795|Chloroflexi	200795|Chloroflexi	K	PFAM response regulator receiver	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_3658572_12	1173023.KE650771_gene2306	3.291e-08	66.0	COG0745@1|root,COG3437@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3437@2|Bacteria,COG5002@2|Bacteria,1G027@1117|Cyanobacteria,1JGSS@1189|Stigonemataceae	1117|Cyanobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Response_reg,Trans_reg_C
CMS1_k127_3658572_9	324602.Caur_0656	8.701e-42	172.0	COG4585@1|root,COG4585@2|Bacteria,2G90K@200795|Chloroflexi,376BE@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA_3
CMS1_k127_3658572_6	869210.Marky_1576	3.531e-67	235.0	COG2197@1|root,COG2197@2|Bacteria,1WI4W@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS1_k127_3658572_11	1380394.JADL01000001_gene2609	1.579e-20	98.0	COG1276@1|root,COG2010@1|root,COG1276@2|Bacteria,COG2010@2|Bacteria,1MXGC@1224|Proteobacteria,2TVGX@28211|Alphaproteobacteria,2JURP@204441|Rhodospirillales	204441|Rhodospirillales	P	Copper resistance protein D	-	-	-	ko:K07245	-	-	-	-	ko00000,ko02000	9.B.62.1	-	-	CopC,CopD
CMS1_k127_3658572_10	706587.Desti_1891	3.407e-33	143.0	COG1290@1|root,COG2010@1|root,COG1290@2|Bacteria,COG2010@2|Bacteria,1MV97@1224|Proteobacteria,42MD6@68525|delta/epsilon subdivisions,2WPA2@28221|Deltaproteobacteria,2MQIC@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Cytochrome b/b6/petB	cbcW	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_B_N_2,Cytochrom_C,Cytochrome_B,Cytochrome_CBB3
CMS1_k127_3658572_4	1183438.GKIL_2541	7.469e-81	278.0	COG0390@1|root,COG0390@2|Bacteria,1G1TY@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Uncharacterised protein family (UPF0014)	-	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0009987,GO:0015075,GO:0016020,GO:0016021,GO:0019725,GO:0022857,GO:0030003,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071944,GO:0098771	-	ko:K02069	-	M00211	-	-	ko00000,ko00002,ko02000	9.B.25.1	-	-	UPF0014
CMS1_k127_3658572_7	71139.XP_010033774.1	4.29e-65	230.0	COG1132@1|root,KOG0055@2759|Eukaryota,37J30@33090|Viridiplantae,3GB0T@35493|Streptophyta	35493|Streptophyta	Q	ABC transporter I family member	-	GO:0003674,GO:0005215,GO:0005338,GO:0005460,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0005774,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0008514,GO:0010035,GO:0010038,GO:0010044,GO:0012506,GO:0015075,GO:0015165,GO:0015711,GO:0015780,GO:0015786,GO:0015931,GO:0015932,GO:0016020,GO:0022857,GO:0031090,GO:0031982,GO:0034220,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090481,GO:0098588,GO:0098656,GO:0098805,GO:1901264,GO:1901505	-	-	-	-	-	-	-	-	-	-	ABC_tran
CMS1_k127_3658572_5	926550.CLDAP_20140	8.17e-71	242.0	COG2193@1|root,COG2193@2|Bacteria,2G6RN@200795|Chloroflexi	200795|Chloroflexi	P	Ferritin-like domain	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
CMS1_k127_3658572_2	357808.RoseRS_3950	2.472e-108	355.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	bshB1	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
CMS1_k127_3658572_8	797209.ZOD2009_13082	3.516e-54	206.0	arCOG10675@1|root,arCOG10675@2157|Archaea,2XUGM@28890|Euryarchaeota,23UF3@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3658572_1	926550.CLDAP_08640	1.71e-124	409.0	COG1388@1|root,COG1506@1|root,COG1388@2|Bacteria,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2920,FecR,LysM,Peptidase_S9
CMS1_k127_3658789_1	926569.ANT_08030	1.81e-189	632.0	COG1361@1|root,COG3764@1|root,COG1361@2|Bacteria,COG3764@2|Bacteria,2G854@200795|Chloroflexi	200795|Chloroflexi	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
CMS1_k127_3658789_15	324602.Caur_0412	1.562e-11	79.0	COG2373@1|root,COG4932@1|root,COG2373@2|Bacteria,COG4932@2|Bacteria,2GABV@200795|Chloroflexi,3752H@32061|Chloroflexia	32061|Chloroflexia	M	Cna B domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,SdrD_B
CMS1_k127_3658789_10	525904.Tter_1099	2.597e-49	195.0	COG2856@1|root,COG2856@2|Bacteria,2NQY0@2323|unclassified Bacteria	2|Bacteria	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3658789_16	1536770.R50345_19380	2.817e-08	55.0	COG0745@1|root,COG0745@2|Bacteria,1TPRM@1239|Firmicutes,4HAMG@91061|Bacilli,274PK@186822|Paenibacillaceae	91061|Bacilli	T	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_3658789_13	616991.JPOO01000003_gene1542	7.792e-32	129.0	COG1917@1|root,COG1917@2|Bacteria,4NRR5@976|Bacteroidetes,1I3Q8@117743|Flavobacteriia	976|Bacteroidetes	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS1_k127_3658789_4	1123508.JH636443_gene4982	5.382e-114	374.0	COG0491@1|root,COG0491@2|Bacteria,2IXNH@203682|Planctomycetes	203682|Planctomycetes	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3658789_9	68570.DC74_7019	4.971e-53	194.0	COG0637@1|root,COG0637@2|Bacteria,2IQD3@201174|Actinobacteria	201174|Actinobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
CMS1_k127_3658789_5	118163.Ple7327_1609	4.496e-111	370.0	COG0430@1|root,COG0430@2|Bacteria,1G3A2@1117|Cyanobacteria	1117|Cyanobacteria	A	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP	rtcA	-	6.5.1.4	ko:K01974	-	-	-	-	ko00000,ko01000	-	-	-	RTC,RTC_insert
CMS1_k127_3658789_3	1128421.JAGA01000003_gene2818	1.012e-123	407.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2NPE1@2323|unclassified Bacteria	2|Bacteria	S	Peptidase family M50	rip3	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K06212,ko:K06402	-	-	-	-	ko00000,ko01000,ko01002,ko02000	1.A.16.1.1,1.A.16.1.3	-	-	CBS,Form_Nir_trans,Peptidase_M50
CMS1_k127_3658789_7	530564.Psta_0688	1.69e-67	246.0	28MMN@1|root,2ZAXE@2|Bacteria,2IY1P@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3658789_14	1313172.YM304_40620	1.605e-23	109.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS1_k127_3658789_12	927677.ALVU02000001_gene2473	7.414e-45	166.0	COG3339@1|root,COG3339@2|Bacteria,1G7DF@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
CMS1_k127_3658789_0	525904.Tter_2055	8.027e-196	617.0	COG1063@1|root,COG1063@2|Bacteria,2NQP5@2323|unclassified Bacteria	2|Bacteria	C	Zinc-binding dehydrogenase	-	GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0008150,GO:0008152,GO:0009056,GO:0009743,GO:0009758,GO:0009987,GO:0010033,GO:0016052,GO:0016491,GO:0016614,GO:0016616,GO:0030246,GO:0042221,GO:0044238,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071322,GO:0071704,GO:1901575,GO:1901700,GO:1901701	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_3658789_8	861299.J421_0662	5.364e-63	218.0	COG2030@1|root,COG2030@2|Bacteria	2|Bacteria	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
CMS1_k127_3658789_11	484770.UFO1_4585	8.109e-49	182.0	COG0500@1|root,COG2226@2|Bacteria,1V3ZV@1239|Firmicutes,4H7ZR@909932|Negativicutes	909932|Negativicutes	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS1_k127_3658789_6	324925.Ppha_1753	3.405e-82	284.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_6,Hydrolase_4
CMS1_k127_3658789_2	1499967.BAYZ01000116_gene3144	8.683e-184	589.0	COG2114@1|root,COG2203@1|root,COG2114@2|Bacteria,COG2203@2|Bacteria,2NP16@2323|unclassified Bacteria	2|Bacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	BLUF,GAF_2,GAF_3,Guanylate_cyc,HAMP,HATPase_c,HisKA,Response_reg
CMS1_k127_3666225_2	56780.SYN_00979	4.254e-104	344.0	COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,42MSF@68525|delta/epsilon subdivisions,2WKJ5@28221|Deltaproteobacteria,2MR0H@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Alanine dehydrogenase/PNT, N-terminal domain	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_1099	AlaDh_PNT_C,AlaDh_PNT_N
CMS1_k127_3666225_0	926550.CLDAP_11170	5.54e-198	627.0	COG0154@1|root,COG0154@2|Bacteria,2G5T0@200795|Chloroflexi	200795|Chloroflexi	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
CMS1_k127_3666225_4	1379698.RBG1_1C00001G0539	6.929e-28	116.0	COG0721@1|root,COG0721@2|Bacteria,2NPXC@2323|unclassified Bacteria	2|Bacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	iAF987.Gmet_0076	Glu-tRNAGln
CMS1_k127_3666225_1	485913.Krac_11524	3.547e-173	557.0	COG0702@1|root,COG0702@2|Bacteria	2|Bacteria	GM	epimerase	ybjT	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF2867,Epimerase,NAD_binding_10
CMS1_k127_3666225_3	926569.ANT_16370	8.807e-50	186.0	COG0406@1|root,COG0406@2|Bacteria,2G7D2@200795|Chloroflexi	200795|Chloroflexi	G	Histidine phosphatase superfamily (branch 1)	-	-	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
CMS1_k127_3667011_6	366394.Smed_1702	4.758e-80	284.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
CMS1_k127_3667011_7	366394.Smed_1701	5.542e-80	277.0	COG1175@1|root,COG1175@2|Bacteria,1NW1N@1224|Proteobacteria,2USPD@28211|Alphaproteobacteria,4BJX3@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_3667011_8	366394.Smed_1700	9.284e-79	274.0	COG0395@1|root,COG0395@2|Bacteria,1MUWS@1224|Proteobacteria,2TS8M@28211|Alphaproteobacteria,4BCNJ@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	Binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_3667011_4	1123501.KB902276_gene1402	2.202e-98	338.0	COG1653@1|root,COG1653@2|Bacteria,1MU64@1224|Proteobacteria,2TTUB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_8
CMS1_k127_3667011_0	1123501.KB902276_gene1401	4.651e-202	647.0	COG0395@1|root,COG1175@1|root,COG0395@2|Bacteria,COG1175@2|Bacteria,1N4I0@1224|Proteobacteria,2TT14@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	ABC-type sugar transport system, permease component	MA20_03550	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_3667011_11	1499967.BAYZ01000041_gene2356	6.547e-45	179.0	COG3356@1|root,COG3356@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
CMS1_k127_3667011_2	926550.CLDAP_10160	2.28e-118	393.0	COG0399@1|root,COG0399@2|Bacteria,2G7WW@200795|Chloroflexi	200795|Chloroflexi	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
CMS1_k127_3667011_1	397948.Cmaq_0837	9.032e-134	437.0	COG0399@1|root,arCOG00118@2157|Archaea,2XQAK@28889|Crenarchaeota	2157|Archaea	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
CMS1_k127_3667011_10	1094715.CM001373_gene3390	5.456e-71	263.0	2EX2Q@1|root,33QDU@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3667011_12	373903.Hore_00780	4.963e-13	81.0	COG1653@1|root,COG1653@2|Bacteria,1TS64@1239|Firmicutes,249GC@186801|Clostridia,3WBTA@53433|Halanaerobiales	186801|Clostridia	G	PFAM Bacterial extracellular solute-binding protein	-	-	-	ko:K02027,ko:K05813	ko02010,map02010	M00198,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.3	-	-	SBP_bac_1,SBP_bac_8
CMS1_k127_3667011_5	697281.Mahau_2566	5.506e-89	304.0	COG1175@1|root,COG1175@2|Bacteria,1TPTZ@1239|Firmicutes,2492R@186801|Clostridia,42FXR@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_3667011_9	935948.KE386495_gene1291	3.909e-75	262.0	COG0395@1|root,COG0395@2|Bacteria,1TSAB@1239|Firmicutes,249PI@186801|Clostridia,42HPU@68295|Thermoanaerobacterales	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_3667011_3	1333998.M2A_2342	1.493e-102	339.0	COG2130@1|root,COG2130@2|Bacteria,1MUC2@1224|Proteobacteria,2TQYM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	NADP-dependent oxidoreductase	-	-	-	ko:K07119	-	-	-	-	ko00000	-	-	-	ADH_N_2,ADH_zinc_N
CMS1_k127_3668445_2	1303518.CCALI_00359	4.946e-08	55.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS1_k127_3668445_0	383372.Rcas_1032	1.354e-185	590.0	COG0161@1|root,COG0161@2|Bacteria,2G62N@200795|Chloroflexi,376DU@32061|Chloroflexia	32061|Chloroflexia	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
CMS1_k127_3668445_1	1089553.Tph_c14180	7.442e-18	97.0	COG1807@1|root,COG1807@2|Bacteria,1V1HJ@1239|Firmicutes,249BG@186801|Clostridia,42HAV@68295|Thermoanaerobacterales	186801|Clostridia	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS1_k127_3670838_5	42256.RradSPS_0358	9.36e-35	134.0	COG2909@1|root,COG2909@2|Bacteria,2HENR@201174|Actinobacteria,4CPC9@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,AAA_22,GerE
CMS1_k127_3670838_4	479434.Sthe_2131	2.405e-137	447.0	COG0436@1|root,COG0436@2|Bacteria,2G5MC@200795|Chloroflexi,27XZ4@189775|Thermomicrobia	200795|Chloroflexi	E	Cys/Met metabolism PLP-dependent enzyme	aspC	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS1_k127_3670838_1	204669.Acid345_2790	9.721e-195	617.0	COG1249@1|root,COG1249@2|Bacteria,3Y2M8@57723|Acidobacteria,2JIAI@204432|Acidobacteriia	2|Bacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation	lpdA	GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006103,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006520,GO:0006544,GO:0006546,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009071,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015036,GO:0016054,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0017144,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019464,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036094,GO:0036211,GO:0042133,GO:0042135,GO:0042737,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0043648,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045250,GO:0045252,GO:0045254,GO:0046390,GO:0046395,GO:0046483,GO:0046496,GO:0046872,GO:0046914,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0065007,GO:0065008,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0097159,GO:0106077,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902494,GO:1990204,GO:1990234	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iAPECO1_1312.APECO1_1869,iEcolC_1368.EcolC_3543,iPC815.YPO3417,iSFV_1184.SFV_0107,iUMN146_1321.UM146_23385	Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim
CMS1_k127_3670838_2	1191523.MROS_0858	5.25e-174	565.0	COG0508@1|root,COG0508@2|Bacteria	2|Bacteria	C	S-acyltransferase activity	aceF	GO:0003674,GO:0003824,GO:0004742,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016407,GO:0016417,GO:0016418,GO:0016740,GO:0016746,GO:0016747,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030523,GO:0031405,GO:0031406,GO:0032787,GO:0032991,GO:0033293,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045254,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1902494,GO:1990204	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iETEC_1333.ETEC_0111,iSSON_1240.SSON_0123,iYL1228.KPN_00119	2-oxoacid_dh,Biotin_lipoyl,E3_binding
CMS1_k127_3670838_0	945713.IALB_2978	0.0	1370.0	COG2609@1|root,COG2609@2|Bacteria	2|Bacteria	C	pyruvate dehydrogenase (acetyl-transferring) activity	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
CMS1_k127_3670838_3	926569.ANT_11950	2.041e-173	558.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,2G674@200795|Chloroflexi	200795|Chloroflexi	H	Homocysteine S-methyltransferase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,S-methyl_trans
CMS1_k127_3671908_5	926550.CLDAP_32290	1.087e-64	224.0	2CD2X@1|root,2Z7RW@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3671908_3	383372.Rcas_2447	3.152e-94	315.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_1,Cupin_2
CMS1_k127_3671908_2	1499967.BAYZ01000095_gene4181	8.639e-157	503.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_3671908_6	1122918.KB907273_gene3525	6.48e-56	201.0	COG1011@1|root,COG1011@2|Bacteria,1UV7E@1239|Firmicutes,4I7MW@91061|Bacilli,26X2S@186822|Paenibacillaceae	91061|Bacilli	S	HAD-hyrolase-like	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
CMS1_k127_3671908_0	1382306.JNIM01000001_gene1635	2.101e-218	686.0	COG0766@1|root,COG0766@2|Bacteria,2G666@200795|Chloroflexi	200795|Chloroflexi	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
CMS1_k127_3671908_7	926550.CLDAP_16420	1.269e-33	139.0	COG0741@1|root,COG1470@1|root,COG0741@2|Bacteria,COG1470@2|Bacteria	2|Bacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,NPCBM_assoc,Phage_HK97_TLTM,SLT
CMS1_k127_3671908_4	926550.CLDAP_18860	6.811e-82	282.0	COG0564@1|root,COG0564@2|Bacteria,2G68N@200795|Chloroflexi	200795|Chloroflexi	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
CMS1_k127_3671908_1	383372.Rcas_2450	4.783e-203	638.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,PqqD,Radical_SAM
CMS1_k127_3683427_10	1122919.KB905571_gene3065	2.757e-32	142.0	COG1653@1|root,COG1653@2|Bacteria,1TQFZ@1239|Firmicutes,4HA0U@91061|Bacilli,26VZR@186822|Paenibacillaceae	91061|Bacilli	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1
CMS1_k127_3683427_8	556261.HMPREF0240_04205	2.205e-66	239.0	COG1175@1|root,COG1175@2|Bacteria,1V109@1239|Firmicutes,24B3N@186801|Clostridia,36VRP@31979|Clostridiaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
CMS1_k127_3683427_7	1321815.HMPREF9193_00553	1.578e-67	239.0	COG0395@1|root,COG0395@2|Bacteria,2J6HM@203691|Spirochaetes	203691|Spirochaetes	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_3683427_3	665571.STHERM_c01980	1.38e-113	377.0	COG3842@1|root,COG3842@2|Bacteria,2J5T3@203691|Spirochaetes	203691|Spirochaetes	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
CMS1_k127_3683427_0	383372.Rcas_2627	5.442e-196	623.0	COG5476@1|root,COG5476@2|Bacteria,2G7N8@200795|Chloroflexi	200795|Chloroflexi	S	MlrC C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	DUF1485,MlrC_C
CMS1_k127_3683427_2	1122132.AQYH01000005_gene446	3.464e-119	399.0	COG1653@1|root,COG1653@2|Bacteria,1MXY4@1224|Proteobacteria,2TS7N@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_1,SBP_bac_8
CMS1_k127_3683427_4	1122132.AQYH01000005_gene445	1.009e-97	328.0	COG1175@1|root,COG1175@2|Bacteria,1MWB7@1224|Proteobacteria,2TUAN@28211|Alphaproteobacteria,4B76N@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	ABC transporter permease	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
CMS1_k127_3683427_5	1122132.AQYH01000005_gene444	1.125e-91	312.0	COG0395@1|root,COG0395@2|Bacteria,1N4I0@1224|Proteobacteria,2TT14@28211|Alphaproteobacteria,4BMAS@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_3683427_1	926550.CLDAP_05690	5.089e-121	399.0	COG0006@1|root,COG0006@2|Bacteria,2G6AE@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the peptidase M24B family	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
CMS1_k127_3683427_6	1123060.JONP01000011_gene3078	1.109e-77	272.0	COG1250@1|root,COG1250@2|Bacteria,1MV8M@1224|Proteobacteria,2TRAW@28211|Alphaproteobacteria,2JW8Q@204441|Rhodospirillales	204441|Rhodospirillales	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	3HCDH,3HCDH_N
CMS1_k127_3683427_9	880073.Calab_2491	3.57e-35	146.0	COG0407@1|root,COG0407@2|Bacteria,2NRD5@2323|unclassified Bacteria	2|Bacteria	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
CMS1_k127_3683874_3	1122137.AQXF01000007_gene3581	1.493e-12	70.0	COG0823@1|root,COG0823@2|Bacteria,1N4BQ@1224|Proteobacteria	1224|Proteobacteria	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
CMS1_k127_3683874_1	857087.Metme_3931	1.581e-44	171.0	COG0577@1|root,COG0577@2|Bacteria,1PJZX@1224|Proteobacteria,1RU56@1236|Gammaproteobacteria,1XDTW@135618|Methylococcales	135618|Methylococcales	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS1_k127_3683874_0	485913.Krac_1500	3.747e-109	368.0	COG3677@1|root,COG3677@2|Bacteria	2|Bacteria	L	transposition, DNA-mediated	-	-	-	ko:K02529,ko:K20971	ko02025,map02025	-	-	-	ko00000,ko00001,ko01001,ko02022,ko03000	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,TniQ
CMS1_k127_3683874_2	1042326.AZNV01000006_gene4418	1.275e-12	68.0	COG0642@1|root,COG2114@1|root,COG2114@2|Bacteria,COG2205@2|Bacteria,1MV1V@1224|Proteobacteria,2U2BQ@28211|Alphaproteobacteria,4B7X4@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Protein of unknown function (DUF3365)	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE3,DUF3365,GAF_2,Guanylate_cyc,HAMP
CMS1_k127_3684788_0	383372.Rcas_3615	1.644e-224	700.0	COG3669@1|root,COG3669@2|Bacteria,2G69T@200795|Chloroflexi,376DN@32061|Chloroflexia	32061|Chloroflexia	G	PFAM glycoside hydrolase family 29 (alpha-L-fucosidase)	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos
CMS1_k127_3684788_5	1385935.N836_31005	3.494e-09	63.0	2E0AY@1|root,32VY9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3684788_2	491916.RHECIAT_PC0000419	1.681e-150	487.0	COG4948@1|root,COG4948@2|Bacteria,1MURK@1224|Proteobacteria,2TRS9@28211|Alphaproteobacteria,4BBEP@82115|Rhizobiaceae	28211|Alphaproteobacteria	M	mandelate racemase muconate lactonizing	-	-	4.2.1.6	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R03033	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
CMS1_k127_3684788_3	595460.RRSWK_00430	4.327e-119	389.0	COG1028@1|root,COG1028@2|Bacteria,2IZ35@203682|Planctomycetes	203682|Planctomycetes	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.127	ko:K00065	ko00040,map00040	-	R01542	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
CMS1_k127_3684788_1	1122917.KB899666_gene3360	1.256e-188	599.0	COG3119@1|root,COG3119@2|Bacteria,1UDRD@1239|Firmicutes,4HD9J@91061|Bacilli,26WKF@186822|Paenibacillaceae	91061|Bacilli	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CMS1_k127_3684788_4	926550.CLDAP_03080	2.106e-87	294.0	COG3010@1|root,COG3010@2|Bacteria	2|Bacteria	G	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)	-	-	5.1.3.9	ko:K01788	ko00520,map00520	-	R02087	RC00290	ko00000,ko00001,ko01000	-	-	-	NanE
CMS1_k127_3687341_2	383372.Rcas_0391	7.531e-128	424.0	COG2133@1|root,COG2133@2|Bacteria,2G62S@200795|Chloroflexi,375V8@32061|Chloroflexia	32061|Chloroflexia	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
CMS1_k127_3687341_5	227377.CBU_0774	1.597e-13	72.0	COG1983@1|root,COG1983@2|Bacteria,1NGIB@1224|Proteobacteria,1T7AM@1236|Gammaproteobacteria,1JF4Z@118969|Legionellales	118969|Legionellales	KT	PspC domain	-	-	-	-	-	-	-	-	-	-	-	-	PspC
CMS1_k127_3687341_0	926550.CLDAP_11790	1.085e-211	687.0	COG2244@1|root,COG4485@1|root,COG2244@2|Bacteria,COG4485@2|Bacteria,2G6CM@200795|Chloroflexi	200795|Chloroflexi	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
CMS1_k127_3687341_3	926550.CLDAP_11790	8.815e-115	385.0	COG2244@1|root,COG4485@1|root,COG2244@2|Bacteria,COG4485@2|Bacteria,2G6CM@200795|Chloroflexi	200795|Chloroflexi	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
CMS1_k127_3687341_4	926550.CLDAP_11780	1.797e-90	303.0	COG1215@1|root,COG1215@2|Bacteria,2GBNZ@200795|Chloroflexi	200795|Chloroflexi	M	Glycosyltransferase like family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
CMS1_k127_3687341_1	926550.CLDAP_07480	1.805e-131	432.0	COG0568@1|root,COG0568@2|Bacteria,2G5W3@200795|Chloroflexi	200795|Chloroflexi	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
CMS1_k127_3687816_1	319795.Dgeo_0678	7.613e-109	358.0	COG0548@1|root,COG0548@2|Bacteria,1WIHT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Belongs to the acetylglutamate kinase family. LysZ subfamily	lysZ	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	-	ko:K05828	ko00220,ko00300,ko01100,ko01110,ko01210,ko01230,map00220,map00300,map01100,map01110,map01210,map01230	M00031,M00763	R09776,R10930	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
CMS1_k127_3687816_0	1128421.JAGA01000001_gene2382	6.217e-133	434.0	COG4992@1|root,COG4992@2|Bacteria,2NP0N@2323|unclassified Bacteria	2|Bacteria	E	acetylornithine and succinylornithine aminotransferase	lysJ	-	2.6.1.11,2.6.1.17	ko:K00821,ko:K05830	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00031,M00763,M00845	R02283,R04475,R09778,R10932	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3,Peptidase_M20
CMS1_k127_3687816_2	357808.RoseRS_2723	3.577e-104	350.0	COG0624@1|root,COG0624@2|Bacteria,2G61X@200795|Chloroflexi,3758J@32061|Chloroflexia	32061|Chloroflexia	E	Catalyzes the release of L-lysine from LysW -gamma-L- lysine	lysK	-	-	ko:K05831	ko00220,ko00300,ko01100,ko01210,ko01230,map00220,map00300,map01100,map01210,map01230	M00031,M00763	R09779,R10933	RC00064,RC00090	ko00000,ko00001,ko00002	-	-	-	Peptidase_M20
CMS1_k127_3687816_3	211165.AJLN01000116_gene3212	3.11e-68	234.0	COG0454@1|root,COG0456@2|Bacteria,1G5GC@1117|Cyanobacteria,1JJAJ@1189|Stigonemataceae	1117|Cyanobacteria	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7
CMS1_k127_3687816_4	649638.Trad_2900	2.116e-42	164.0	COG2345@1|root,COG2345@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	ATC_hydrolase,SWIM
CMS1_k127_370073_1	1121087.AUCK01000032_gene84	4.03e-65	229.0	COG0294@1|root,COG0294@2|Bacteria,1TPKT@1239|Firmicutes,4H9SY@91061|Bacilli,1ZAPZ@1386|Bacillus	91061|Bacilli	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
CMS1_k127_370073_0	1128421.JAGA01000001_gene2151	1.163e-108	360.0	COG1957@1|root,COG1957@2|Bacteria,2NPG1@2323|unclassified Bacteria	2|Bacteria	F	Inosine-uridine preferring nucleoside hydrolase	iunH	-	3.2.2.1	ko:K01239,ko:K01250	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
CMS1_k127_370073_2	935948.KE386494_gene874	1.167e-21	105.0	COG1082@1|root,COG1082@2|Bacteria,1V08R@1239|Firmicutes,24C9W@186801|Clostridia,42J0W@68295|Thermoanaerobacterales	186801|Clostridia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS1_k127_370073_3	1210045.ALNP01000035_gene2386	1.214e-18	89.0	COG1028@1|root,COG1028@2|Bacteria,2GNIN@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS1_k127_3702448_1	865861.AZSU01000001_gene386	6.089e-72	255.0	COG0842@1|root,COG0842@2|Bacteria,1VI3K@1239|Firmicutes,24AR2@186801|Clostridia,36F7U@31979|Clostridiaceae	186801|Clostridia	V	ABC-2 type transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane
CMS1_k127_3702448_0	926569.ANT_02350	5.867e-125	409.0	COG1131@1|root,COG1131@2|Bacteria,2G5RD@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
CMS1_k127_3702448_2	385682.AFSL01000087_gene713	4.552e-50	188.0	COG1262@1|root,COG1262@2|Bacteria,4NFR2@976|Bacteroidetes,2FUVV@200643|Bacteroidia,3XKS5@558415|Marinilabiliaceae	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
CMS1_k127_3702448_3	1347392.CCEZ01000014_gene2743	8.827e-14	83.0	28MQQ@1|root,2ZAZI@2|Bacteria,1U6SZ@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3702448_4	743719.PaelaDRAFT_4334	2.191e-07	54.0	COG1595@1|root,COG1595@2|Bacteria,1VHBD@1239|Firmicutes,4HK7X@91061|Bacilli,2730Y@186822|Paenibacillaceae	91061|Bacilli	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_3709383_4	316274.Haur_2673	1.561e-48	189.0	COG1668@1|root,COG1668@2|Bacteria,2G8PJ@200795|Chloroflexi	200795|Chloroflexi	CP	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
CMS1_k127_3709383_0	316274.Haur_2672	5.136e-94	321.0	COG4152@1|root,COG4152@2|Bacteria	2|Bacteria	S	ATPase activity	ecsA_1	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
CMS1_k127_3709383_1	926550.CLDAP_30370	2.595e-93	332.0	COG3391@1|root,COG4745@1|root,COG3391@2|Bacteria,COG4745@2|Bacteria,2G5PE@200795|Chloroflexi	200795|Chloroflexi	O	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NHL,PMT_2
CMS1_k127_3709383_3	216594.MMAR_3393	2.287e-66	233.0	COG0500@1|root,COG2226@2|Bacteria,2H9G5@201174|Actinobacteria,2374J@1762|Mycobacteriaceae	201174|Actinobacteria	Q	Hypothetical methyltransferase	pmtA	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS1_k127_3709383_2	1382356.JQMP01000004_gene447	1.871e-67	230.0	COG4948@1|root,COG4948@2|Bacteria,2G69R@200795|Chloroflexi,27YWW@189775|Thermomicrobia	189775|Thermomicrobia	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
CMS1_k127_3715410_1	56107.Cylst_5770	5.29e-56	198.0	COG3119@1|root,COG3119@2|Bacteria,1G22U@1117|Cyanobacteria,1HU48@1161|Nostocales	1117|Cyanobacteria	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
CMS1_k127_3715410_8	1460635.JCM19038_4144	0.000172	49.0	COG4980@1|root,COG4980@2|Bacteria,1VFY7@1239|Firmicutes,4HJX4@91061|Bacilli	91061|Bacilli	S	YtxH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
CMS1_k127_3715410_6	388467.A19Y_1879	1.593e-22	106.0	COG4803@1|root,COG4803@2|Bacteria,1GA6S@1117|Cyanobacteria,1HEWV@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function (DUF1269)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1269
CMS1_k127_3715410_2	65393.PCC7424_4845	6.176e-38	156.0	COG3861@1|root,COG3861@2|Bacteria,1GM7B@1117|Cyanobacteria,3KJPH@43988|Cyanothece	1117|Cyanobacteria	S	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3715410_7	1218076.BAYB01000029_gene4850	5.227e-09	68.0	COG4803@1|root,COG4803@2|Bacteria,1NAP8@1224|Proteobacteria,2VXX0@28216|Betaproteobacteria,1K9R4@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1269)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1269
CMS1_k127_3715410_4	118166.JH976538_gene5295	1.559e-32	140.0	COG3861@1|root,COG3861@2|Bacteria,1GE1R@1117|Cyanobacteria	1117|Cyanobacteria	S	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3715410_0	926550.CLDAP_27170	3.224e-101	339.0	COG4690@1|root,COG4690@2|Bacteria,2G7Y7@200795|Chloroflexi	200795|Chloroflexi	E	Peptidase family C69	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C69
CMS1_k127_3715410_5	926569.ANT_10840	7.733e-24	106.0	COG4690@1|root,COG4690@2|Bacteria,2G7Y7@200795|Chloroflexi	200795|Chloroflexi	E	Peptidase family C69	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C69
CMS1_k127_3722892_4	215803.DB30_7525	4.188e-22	102.0	COG4485@1|root,COG4485@2|Bacteria,1NBM0@1224|Proteobacteria,42WPS@68525|delta/epsilon subdivisions,2WS8D@28221|Deltaproteobacteria,2YXF4@29|Myxococcales	28221|Deltaproteobacteria	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
CMS1_k127_3722892_2	926550.CLDAP_11940	1.648e-59	233.0	COG4745@1|root,COG4745@2|Bacteria,2G8SI@200795|Chloroflexi	2|Bacteria	O	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS1_k127_3722892_1	485913.Krac_2032	2.578e-75	258.0	COG0645@1|root,COG0645@2|Bacteria	2|Bacteria	S	AAA domain	-	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_18,AAA_33,Zeta_toxin
CMS1_k127_3722892_3	926550.CLDAP_21430	1.767e-43	181.0	COG5305@1|root,COG5305@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2142,PMT_2
CMS1_k127_3722892_0	592027.CLG_B0074	9.171e-101	335.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,248I8@186801|Clostridia,36DNY@31979|Clostridiaceae	186801|Clostridia	E	Methionine aminopeptidase	-	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24,SEC-C
CMS1_k127_3730367_3	1122915.AUGY01000065_gene5608	1.022e-21	97.0	COG5285@1|root,COG5285@2|Bacteria	2|Bacteria	Q	dioxygenase activity	-	-	-	ko:K18565	ko00332,ko01130,map00332,map01130	-	R10740,R10741,R10742	RC03267,RC03268,RC03269	ko00000,ko00001,ko01000	-	-	-	PhyH
CMS1_k127_3730367_2	411902.CLOBOL_02420	2.6e-58	213.0	COG1028@1|root,COG1028@2|Bacteria,1TPZ8@1239|Firmicutes	1239|Firmicutes	IQ	Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)	-	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
CMS1_k127_3730367_1	926550.CLDAP_15120	5.165e-79	274.0	COG0491@1|root,COG0491@2|Bacteria,2G8NI@200795|Chloroflexi	200795|Chloroflexi	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS1_k127_3730367_0	649638.Trad_2186	9.023e-101	336.0	COG1063@1|root,COG1063@2|Bacteria,1WMH7@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_3734091_3	926569.ANT_02400	5.323e-74	255.0	COG0381@1|root,COG0381@2|Bacteria,2G7S6@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	-	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
CMS1_k127_3734091_2	880073.Calab_0603	4.885e-106	357.0	COG0438@1|root,COG0438@2|Bacteria,2NQ20@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferases group 1	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CMS1_k127_3734091_5	330214.NIDE0884	1.836e-52	194.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	rhiI	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0009273,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016741,GO:0022607,GO:0032259,GO:0042546,GO:0044085,GO:0044464,GO:0071554,GO:0071766,GO:0071770,GO:0071840,GO:0071944	-	ko:K15471	-	-	-	-	ko00000,ko01000,ko01008	-	-	-	Methyltransf_11,Methyltransf_25
CMS1_k127_3734091_4	234267.Acid_1421	5.749e-66	246.0	COG1807@1|root,COG1807@2|Bacteria,3Y2T0@57723|Acidobacteria	2|Bacteria	M	PFAM glycosyl transferase family 39	-	-	-	ko:K14340	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	PMT_2
CMS1_k127_3734091_1	768704.Desmer_4328	3.99e-122	403.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,24862@186801|Clostridia,261AB@186807|Peptococcaceae	186801|Clostridia	E	Belongs to the DegT DnrJ EryC1 family	spsC	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
CMS1_k127_3734091_0	251229.Chro_5085	3.216e-147	497.0	COG1086@1|root,COG2200@1|root,COG1086@2|Bacteria,COG2200@2|Bacteria,1G18C@1117|Cyanobacteria,3VI4Z@52604|Pleurocapsales	1117|Cyanobacteria	GM	PFAM polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,EAL,Polysacc_synt_2
CMS1_k127_3738654_14	634498.mru_1288	8.372e-12	72.0	COG0639@1|root,arCOG01143@2157|Archaea,2Y3W3@28890|Euryarchaeota,23PN1@183925|Methanobacteria	183925|Methanobacteria	T	Protein phosphatase 2A homologues, catalytic domain.	-	-	3.1.3.16	ko:K06269	ko03015,ko04022,ko04024,ko04113,ko04114,ko04218,ko04261,ko04270,ko04390,ko04510,ko04611,ko04720,ko04728,ko04750,ko04810,ko04910,ko04921,ko04931,ko05031,ko05034,ko05168,ko05205,map03015,map04022,map04024,map04113,map04114,map04218,map04261,map04270,map04390,map04510,map04611,map04720,map04728,map04750,map04810,map04910,map04921,map04931,map05031,map05034,map05168,map05205	-	-	-	ko00000,ko00001,ko01000,ko01009,ko03019,ko03021,ko03041	-	-	-	Metallophos
CMS1_k127_3738654_4	357808.RoseRS_1065	1.05e-107	361.0	COG0297@1|root,COG0297@2|Bacteria,2G7ZU@200795|Chloroflexi,375BU@32061|Chloroflexia	32061|Chloroflexia	G	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS1_k127_3738654_16	926550.CLDAP_11420	1.482e-09	66.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
CMS1_k127_3738654_9	926550.CLDAP_36810	6.016e-34	134.0	COG3824@1|root,COG3824@2|Bacteria,2G72E@200795|Chloroflexi	200795|Chloroflexi	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
CMS1_k127_3738654_6	326427.Cagg_1576	3.794e-65	229.0	2CAZH@1|root,2Z7RU@2|Bacteria,2G8SJ@200795|Chloroflexi,375P9@32061|Chloroflexia	32061|Chloroflexia	C	TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
CMS1_k127_3738654_0	326427.Cagg_1577	0.0	1065.0	COG1053@1|root,COG1053@2|Bacteria,2G5YB@200795|Chloroflexi,374WX@32061|Chloroflexia	32061|Chloroflexia	C	TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
CMS1_k127_3738654_2	926550.CLDAP_30830	4.936e-123	398.0	COG0479@1|root,COG0479@2|Bacteria,2G659@200795|Chloroflexi	200795|Chloroflexi	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_8
CMS1_k127_3738654_1	926550.CLDAP_02840	5.692e-128	423.0	COG2723@1|root,COG2723@2|Bacteria,2G5QE@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycoside hydrolase, family 1	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
CMS1_k127_3738654_11	485913.Krac_7649	9.347e-29	121.0	COG0818@1|root,COG0818@2|Bacteria,2G75I@200795|Chloroflexi	200795|Chloroflexi	M	PFAM diacylglycerol kinase	-	-	2.7.1.107	ko:K00901	ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
CMS1_k127_3738654_10	357808.RoseRS_3596	2.448e-29	122.0	COG0319@1|root,COG0319@2|Bacteria,2G78D@200795|Chloroflexi,375VQ@32061|Chloroflexia	32061|Chloroflexia	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
CMS1_k127_3738654_3	926550.CLDAP_16370	5.965e-121	415.0	COG1480@1|root,COG1480@2|Bacteria,2G5WC@200795|Chloroflexi	200795|Chloroflexi	S	metal-dependent phosphohydrolase, HD sub domain	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
CMS1_k127_3738654_8	401526.TcarDRAFT_1260	2.035e-36	143.0	COG1610@1|root,COG1610@2|Bacteria,1V6F2@1239|Firmicutes,4H4MK@909932|Negativicutes	909932|Negativicutes	S	YqeY-like protein	yqeY	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
CMS1_k127_3738654_12	265729.GS18_0218225	2.594e-13	76.0	COG0745@1|root,COG0745@2|Bacteria,1TS8Z@1239|Firmicutes,4HC86@91061|Bacilli,1ZB3W@1386|Bacillus	91061|Bacilli	KT	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_3738654_5	926550.CLDAP_07480	4.437e-103	348.0	COG0568@1|root,COG0568@2|Bacteria,2G5W3@200795|Chloroflexi	200795|Chloroflexi	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
CMS1_k127_3738654_15	278963.ATWD01000001_gene3069	2.076e-10	70.0	2AZDP@1|root,31RMA@2|Bacteria,3Y4JB@57723|Acidobacteria,2JJ76@204432|Acidobacteriia	204432|Acidobacteriia	S	Protein of unknown function (DUF4230)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4230
CMS1_k127_3738654_13	926550.CLDAP_25200	1.252e-12	69.0	COG1816@1|root,COG1816@2|Bacteria,2G6AT@200795|Chloroflexi	200795|Chloroflexi	F	PFAM Adenosine AMP deaminase	-	-	3.5.4.4,3.5.4.40	ko:K01488,ko:K18286	ko00130,ko00230,ko01100,ko01110,ko05340,map00130,map00230,map01100,map01110,map05340	-	R01560,R02556,R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
CMS1_k127_3742920_2	525904.Tter_1733	1.35e-18	91.0	COG1651@1|root,COG1651@2|Bacteria,2NPXE@2323|unclassified Bacteria	2|Bacteria	O	Thioredoxin	bdbD	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
CMS1_k127_3742920_1	292459.STH2564	1.78e-25	112.0	COG4243@1|root,COG4243@2|Bacteria	2|Bacteria	S	quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4,VKOR
CMS1_k127_3742920_4	1122143.AUEG01000004_gene1250	2.256e-08	58.0	COG1396@1|root,COG1396@2|Bacteria,1VETP@1239|Firmicutes,4HQKC@91061|Bacilli,27HYR@186828|Carnobacteriaceae	91061|Bacilli	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
CMS1_k127_3742920_0	1379698.RBG1_1C00001G0743	1.675e-33	139.0	COG2318@1|root,COG2318@2|Bacteria,2NRHG@2323|unclassified Bacteria	2|Bacteria	S	DinB superfamily	dinB	-	-	ko:K07552	-	-	-	-	ko00000,ko02000	2.A.1.2	-	-	DinB
CMS1_k127_3752635_2	1308866.J416_01629	9.968e-96	327.0	COG0477@1|root,COG2814@2|Bacteria,1TS6K@1239|Firmicutes,4HB1V@91061|Bacilli,4701R@74385|Gracilibacillus	91061|Bacilli	EGP	MFS_1 like family	tetA_3	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like,Sugar_tr
CMS1_k127_3752635_4	926550.CLDAP_04490	8.651e-40	171.0	COG0823@1|root,COG3103@1|root,COG0823@2|Bacteria,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	NLPC_P60,Rick_17kDa_Anti,SH3_3
CMS1_k127_3752635_0	868595.Desca_0320	8.472e-216	709.0	COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,2491S@186801|Clostridia,260CZ@186807|Peptococcaceae	186801|Clostridia	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
CMS1_k127_3752635_5	313612.L8106_19451	1.636e-32	143.0	COG0845@1|root,COG0845@2|Bacteria,1G0KI@1117|Cyanobacteria,1H9J7@1150|Oscillatoriales	1117|Cyanobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
CMS1_k127_3752635_6	314230.DSM3645_17240	7.639e-09	64.0	COG1846@1|root,COG1846@2|Bacteria,2IZDD@203682|Planctomycetes	203682|Planctomycetes	K	COG1846 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	MarR
CMS1_k127_3752635_3	926550.CLDAP_11800	2.396e-59	211.0	COG2453@1|root,COG2453@2|Bacteria,2G7AB@200795|Chloroflexi	200795|Chloroflexi	T	PFAM Dual specificity protein phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	DSPc
CMS1_k127_3752635_1	1121423.JONT01000026_gene903	3.085e-99	330.0	COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,247VX@186801|Clostridia,260CD@186807|Peptococcaceae	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon,tRNA_bind
CMS1_k127_3753791_1	926550.CLDAP_14080	2.158e-59	214.0	COG0745@1|root,COG0745@2|Bacteria	926550.CLDAP_14080|-	T	phosphorelay signal transduction system	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	-
CMS1_k127_3753791_2	530564.Psta_3548	3.586e-52	189.0	COG2062@1|root,COG2062@2|Bacteria,2J0N8@203682|Planctomycetes	203682|Planctomycetes	T	phosphohistidine phosphatase, SixA	-	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
CMS1_k127_3753791_0	1120950.KB892751_gene6801	1.537e-83	287.0	COG0477@1|root,COG2814@2|Bacteria,2IDJ6@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_3755946_0	926550.CLDAP_24610	1.92e-112	369.0	COG0343@1|root,COG0343@2|Bacteria,2G5RE@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
CMS1_k127_3755946_6	926550.CLDAP_24620	4.774e-62	223.0	COG1968@1|root,COG1968@2|Bacteria,2G6F7@200795|Chloroflexi	200795|Chloroflexi	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
CMS1_k127_3755946_10	351627.Csac_1610	5.057e-30	129.0	COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,248QU@186801|Clostridia,42EPR@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM extracellular solute-binding protein family 1	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
CMS1_k127_3755946_5	716544.wcw_1745	1.675e-64	229.0	COG0566@1|root,COG0566@2|Bacteria,2JFQK@204428|Chlamydiae	204428|Chlamydiae	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	spoU_1	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
CMS1_k127_3755946_1	720554.Clocl_1068	4.69e-99	331.0	COG1092@1|root,COG1092@2|Bacteria,1TPUD@1239|Firmicutes,2480X@186801|Clostridia,3WGYH@541000|Ruminococcaceae	186801|Clostridia	J	S-adenosylmethionine-dependent methyltransferase	rlmL_1	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
CMS1_k127_3755946_8	867845.KI911784_gene2338	3.716e-41	168.0	COG0392@1|root,COG0392@2|Bacteria,2G5KF@200795|Chloroflexi,374YY@32061|Chloroflexia	32061|Chloroflexia	S	PFAM conserved	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
CMS1_k127_3755946_11	926569.ANT_30100	8.705e-27	126.0	COG2905@1|root,COG2905@2|Bacteria	2|Bacteria	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin,Lactamase_B,Lactamase_B_2,cNMP_binding
CMS1_k127_3755946_3	383372.Rcas_1749	1.008e-82	278.0	COG2360@1|root,COG2360@2|Bacteria,2G8HE@200795|Chloroflexi,375I4@32061|Chloroflexia	32061|Chloroflexia	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
CMS1_k127_3755946_9	1121430.JMLG01000001_gene2213	1.18e-36	158.0	COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,248G1@186801|Clostridia,260NT@186807|Peptococcaceae	186801|Clostridia	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1,HHH_3
CMS1_k127_3755946_7	404380.Gbem_2066	3.253e-46	192.0	COG1470@1|root,COG2132@1|root,COG3386@1|root,COG1470@2|Bacteria,COG2132@2|Bacteria,COG3386@2|Bacteria,1R9AF@1224|Proteobacteria,42YQG@68525|delta/epsilon subdivisions,2WTP2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Multicopper oxidase	ompB	-	-	-	-	-	-	-	-	-	-	-	ASH,Cu-oxidase_2
CMS1_k127_3755946_4	163908.KB235896_gene3916	3.497e-76	288.0	COG3266@1|root,COG3267@1|root,COG3266@2|Bacteria,COG3267@2|Bacteria,1G3CE@1117|Cyanobacteria,1HSFH@1161|Nostocales	1117|Cyanobacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC
CMS1_k127_3755946_12	1499967.BAYZ01000125_gene2606	1.391e-07	55.0	2C9PJ@1|root,32RPM@2|Bacteria	1499967.BAYZ01000125_gene2606|-	S	PFAM XisI protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3755946_2	485913.Krac_6031	2.757e-98	325.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS1_k127_3759471_7	76114.ebA3146	1.03e-05	53.0	COG3787@1|root,COG3787@2|Bacteria,1PV3C@1224|Proteobacteria,2WB2H@28216|Betaproteobacteria,2KYQQ@206389|Rhodocyclales	206389|Rhodocyclales	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K09979	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
CMS1_k127_3759471_0	439235.Dalk_2025	5.334e-174	569.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42MV1@68525|delta/epsilon subdivisions,2WK9W@28221|Deltaproteobacteria,2MIZ9@213118|Desulfobacterales	28221|Deltaproteobacteria	V	PFAM ABC transporter	ybhF-C	-	-	ko:K01990,ko:K09695	ko02010,map02010	M00252,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.102	-	-	ABC_tran,DUF4162
CMS1_k127_3759471_1	1177154.Y5S_00554	3.239e-106	356.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,1RPB4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	ABC-type multidrug transport system, permease component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC2_membrane_3
CMS1_k127_3759471_2	1384056.N787_01670	7.416e-71	255.0	COG0842@1|root,COG0842@2|Bacteria,1MUIA@1224|Proteobacteria,1RQSE@1236|Gammaproteobacteria,1X7D8@135614|Xanthomonadales	135614|Xanthomonadales	V	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_3
CMS1_k127_3759471_5	309799.DICTH_1470	4.691e-11	66.0	COG3350@1|root,COG3350@2|Bacteria	2|Bacteria	T	monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI,YHS
CMS1_k127_3759471_6	309800.C498_11641	2.488e-09	62.0	COG0701@1|root,arCOG02712@2157|Archaea,2XU5I@28890|Euryarchaeota,23T00@183963|Halobacteria	183963|Halobacteria	S	metal ion permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1,YHS
CMS1_k127_3759471_3	765420.OSCT_0043	8.829e-69	251.0	COG0845@1|root,COG1566@1|root,COG0845@2|Bacteria,COG1566@2|Bacteria,2G93B@200795|Chloroflexi,3764W@32061|Chloroflexia	32061|Chloroflexia	MV	PFAM secretion protein HlyD family protein	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23
CMS1_k127_3759471_4	518766.Rmar_1777	1.925e-33	145.0	COG1566@1|root,COG1566@2|Bacteria,4PKPZ@976|Bacteroidetes	976|Bacteroidetes	V	HlyD family secretion protein	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
CMS1_k127_3766667_6	552811.Dehly_0206	5.213e-27	124.0	COG0477@1|root,COG0477@2|Bacteria,2G7N2@200795|Chloroflexi	200795|Chloroflexi	P	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_3766667_1	426117.M446_1932	4.873e-97	332.0	COG2079@1|root,COG2079@2|Bacteria,1R5UM@1224|Proteobacteria,2U1F8@28211|Alphaproteobacteria,1JWG7@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	MmgE/PrpD family	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
CMS1_k127_3766667_0	266117.Rxyl_0363	1.616e-111	375.0	COG0683@1|root,COG0683@2|Bacteria,2I8ME@201174|Actinobacteria,4CQWB@84995|Rubrobacteria	84995|Rubrobacteria	E	Receptor family ligand binding region	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
CMS1_k127_3766667_3	266117.Rxyl_0362	2.117e-87	299.0	COG0559@1|root,COG0559@2|Bacteria,2GKAR@201174|Actinobacteria,4CQ8M@84995|Rubrobacteria	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
CMS1_k127_3766667_2	266117.Rxyl_0361	2.538e-96	325.0	COG4177@1|root,COG4177@2|Bacteria,2I93C@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
CMS1_k127_3766667_5	266117.Rxyl_0360	1.306e-76	263.0	COG0411@1|root,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria,4CPJW@84995|Rubrobacteria	84995|Rubrobacteria	E	PFAM ABC transporter related	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
CMS1_k127_3766667_4	748224.HMPREF9436_01728	1.53e-78	269.0	COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,247PN@186801|Clostridia,3WHG1@541000|Ruminococcaceae	186801|Clostridia	E	ABC transporter, ATP-binding protein	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
CMS1_k127_3766667_7	1123355.JHYO01000009_gene3063	0.0001073	46.0	COG1942@1|root,COG1942@2|Bacteria,1QVEA@1224|Proteobacteria,2TWDD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2,Tautomerase
CMS1_k127_3775047_5	1279009.ADICEAN_00595	3.539e-85	292.0	COG4099@1|root,COG4099@2|Bacteria,4NFSH@976|Bacteroidetes	976|Bacteroidetes	E	Phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2,Peptidase_S9
CMS1_k127_3775047_9	1501230.ET33_29820	4.174e-41	158.0	COG2306@1|root,COG2306@2|Bacteria,1VARK@1239|Firmicutes,4HHJ8@91061|Bacilli,26S4W@186822|Paenibacillaceae	91061|Bacilli	S	Protein of unknown function (DUF402)	-	-	-	ko:K09145	-	-	-	-	ko00000	-	-	-	DUF402
CMS1_k127_3775047_12	573061.Clocel_3279	4.984e-27	117.0	COG0454@1|root,COG0456@2|Bacteria,1VJ9N@1239|Firmicutes,24KBX@186801|Clostridia,36RW9@31979|Clostridiaceae	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS1_k127_3775047_10	1449050.JNLE01000005_gene5226	4.875e-29	126.0	COG0546@1|root,COG0546@2|Bacteria	2|Bacteria	S	glycolate biosynthetic process	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD,HAD_2,UbiA
CMS1_k127_3775047_11	306281.AJLK01000026_gene2183	5.418e-28	118.0	COG0454@1|root,COG0456@2|Bacteria,1GDTV@1117|Cyanobacteria,1JMHR@1189|Stigonemataceae	1117|Cyanobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS1_k127_3775047_15	1382356.JQMP01000003_gene1515	5.552e-15	83.0	COG4454@1|root,COG4454@2|Bacteria,2GBF0@200795|Chloroflexi,27Z8J@189775|Thermomicrobia	189775|Thermomicrobia	P	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
CMS1_k127_3775047_13	935840.JAEQ01000020_gene2336	6.694e-23	104.0	COG0526@1|root,COG0526@2|Bacteria,1RC8N@1224|Proteobacteria,2U7IW@28211|Alphaproteobacteria,43NJ4@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS1_k127_3775047_1	935840.JAEQ01000020_gene2336	1.098e-201	636.0	COG0526@1|root,COG0526@2|Bacteria,1RC8N@1224|Proteobacteria,2U7IW@28211|Alphaproteobacteria,43NJ4@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS1_k127_3775047_0	926569.ANT_24910	2.397e-254	791.0	COG1070@1|root,COG1070@2|Bacteria,2G5QX@200795|Chloroflexi	200795|Chloroflexi	G	PFAM carbohydrate kinase	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
CMS1_k127_3775047_2	525904.Tter_2606	2.486e-122	401.0	COG0673@1|root,COG0673@2|Bacteria,2NRDJ@2323|unclassified Bacteria	2|Bacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_3775047_3	1131462.DCF50_p77	1.372e-119	398.0	COG1055@1|root,COG1055@2|Bacteria,1TPNN@1239|Firmicutes,2494X@186801|Clostridia,261AN@186807|Peptococcaceae	186801|Clostridia	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
CMS1_k127_3775047_17	1499684.CCNP01000018_gene1116	1.91e-07	62.0	COG0347@1|root,COG0347@2|Bacteria,1UJDU@1239|Firmicutes,25F29@186801|Clostridia,36UVX@31979|Clostridiaceae	186801|Clostridia	E	Belongs to the P(II) protein family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3775047_18	247490.KSU1_C1654	0.0003177	52.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,HYR,SLH,VCBS
CMS1_k127_3775047_16	243232.MJ_0990	4.404e-09	60.0	COG0425@1|root,arCOG02062@2157|Archaea,2Y0J1@28890|Euryarchaeota,23R7Y@183939|Methanococci	183939|Methanococci	O	PFAM SirA family protein	-	GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	TusA
CMS1_k127_3775047_7	264732.Moth_0449	5.564e-61	226.0	COG2391@1|root,COG2391@2|Bacteria,1TSNG@1239|Firmicutes,25DZC@186801|Clostridia,42J5H@68295|Thermoanaerobacterales	186801|Clostridia	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
CMS1_k127_3775047_8	765420.OSCT_2145	2.536e-57	209.0	COG2897@1|root,COG2897@2|Bacteria	2|Bacteria	P	thiosulfate sulfurtransferase activity	rhdA	-	2.8.1.1,2.8.1.2,4.1.1.65	ko:K01011,ko:K01613	ko00270,ko00564,ko00920,ko01100,ko01110,ko01120,ko04122,map00270,map00564,map00920,map01100,map01110,map01120,map04122	M00093	R01931,R02055,R03105,R03106	RC00214,RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Rhodanese
CMS1_k127_3775047_14	373994.Riv7116_4517	2.343e-18	94.0	COG1100@1|root,COG4886@1|root,COG1100@2|Bacteria,COG4886@2|Bacteria,1G05B@1117|Cyanobacteria,1HJS7@1161|Nostocales	1117|Cyanobacteria	S	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,COR,LRR_4,LRR_8,Roc
CMS1_k127_3775047_4	1121904.ARBP01000014_gene138	8.936e-86	293.0	COG1028@1|root,COG1028@2|Bacteria,4NFDX@976|Bacteroidetes,47NTC@768503|Cytophagia	976|Bacteroidetes	IQ	KR domain	-	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
CMS1_k127_3775047_6	266265.Bxe_C0294	1.436e-61	225.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2VJ55@28216|Betaproteobacteria,1JZU0@119060|Burkholderiaceae	28216|Betaproteobacteria	H	acetolactate synthase	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS1_k127_3776280_0	1173027.Mic7113_2172	1.574e-296	957.0	COG2319@1|root,COG3903@1|root,COG2319@2|Bacteria,COG3903@2|Bacteria,1FZVW@1117|Cyanobacteria,1H7R4@1150|Oscillatoriales	1117|Cyanobacteria	K	Wd40 repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GerE,NB-ARC,Pentapeptide,WD40
CMS1_k127_3776280_1	1487953.JMKF01000089_gene5400	1.772e-46	194.0	COG3629@1|root,COG5635@1|root,COG3629@2|Bacteria,COG5635@2|Bacteria,1G14T@1117|Cyanobacteria,1H8RF@1150|Oscillatoriales	1117|Cyanobacteria	T	Ntpase (Nacht family)	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	NACHT,Pkinase,TIR_2
CMS1_k127_3776280_3	1121904.ARBP01000005_gene4723	0.0001331	52.0	COG4935@1|root,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CHU_C,CUB,Calx-beta,Cleaved_Adhesin,DUF11,HYR,P_proprotein,SdrD_B,fn3
CMS1_k127_3781658_1	357808.RoseRS_0169	2.662e-102	339.0	COG1122@1|root,COG1122@2|Bacteria,2G6RD@200795|Chloroflexi,3764I@32061|Chloroflexia	32061|Chloroflexia	P	ABC transporter	-	-	-	ko:K02006	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	ABC_tran
CMS1_k127_3781658_2	357808.RoseRS_0170	1.715e-88	299.0	COG0619@1|root,COG0619@2|Bacteria,2G7CE@200795|Chloroflexi,37758@32061|Chloroflexia	32061|Chloroflexia	P	TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ	-	-	-	ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
CMS1_k127_3781658_0	357808.RoseRS_0174	2.733e-117	387.0	COG0310@1|root,COG0310@2|Bacteria,2G6ZN@200795|Chloroflexi,376DK@32061|Chloroflexia	32061|Chloroflexia	P	PFAM cobalamin (vitamin B12) biosynthesis CbiM protein	-	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM,PDGLE
CMS1_k127_3781658_3	479434.Sthe_1819	9.018e-36	140.0	COG0735@1|root,COG0735@2|Bacteria,2G723@200795|Chloroflexi,27Z9F@189775|Thermomicrobia	189775|Thermomicrobia	P	Ferric uptake regulator family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
CMS1_k127_3782672_1	926550.CLDAP_20700	1.971e-73	251.0	COG1136@1|root,COG1136@2|Bacteria,2G6K8@200795|Chloroflexi	200795|Chloroflexi	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_3782672_0	926550.CLDAP_20690	5.53e-122	403.0	COG0577@1|root,COG0577@2|Bacteria,2G6RX@200795|Chloroflexi	200795|Chloroflexi	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
CMS1_k127_3790673_3	926550.CLDAP_21830	2.83e-14	82.0	COG1376@1|root,COG1376@2|Bacteria,2G9TK@200795|Chloroflexi	200795|Chloroflexi	S	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3790673_1	29730.Gorai.006G195500.1	9.147e-59	212.0	COG0193@1|root,KOG2255@2759|Eukaryota,37HFV@33090|Viridiplantae,3G8N9@35493|Streptophyta	35493|Streptophyta	J	Belongs to the PTH family	-	GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0016787,GO:0016788,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
CMS1_k127_3790673_0	926550.CLDAP_21810	0.0	1043.0	COG1197@1|root,COG1197@2|Bacteria,2G5UW@200795|Chloroflexi	200795|Chloroflexi	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
CMS1_k127_3801231_1	314278.NB231_07487	1.332e-113	374.0	COG1893@1|root,COG1893@2|Bacteria,1MX5M@1224|Proteobacteria,1RYQS@1236|Gammaproteobacteria,1WWAX@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
CMS1_k127_3801231_4	68260.JOAY01000028_gene4154	9.663e-15	84.0	COG0500@1|root,COG2226@2|Bacteria,2GK7A@201174|Actinobacteria	201174|Actinobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_31
CMS1_k127_3801231_2	448385.sce8469	3.642e-80	276.0	COG0639@1|root,COG0639@2|Bacteria,1QQKD@1224|Proteobacteria,43EN6@68525|delta/epsilon subdivisions,2X9QX@28221|Deltaproteobacteria,2YYXC@29|Myxococcales	28221|Deltaproteobacteria	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
CMS1_k127_3801231_3	479434.Sthe_3410	2.772e-50	188.0	COG0500@1|root,COG2890@1|root,COG2226@2|Bacteria,COG2890@2|Bacteria,2G9F9@200795|Chloroflexi	200795|Chloroflexi	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3801231_0	479434.Sthe_3409	3.773e-219	689.0	COG1032@1|root,COG1032@2|Bacteria,2G6ZI@200795|Chloroflexi	200795|Chloroflexi	C	SMART Elongator protein 3 MiaB NifB	-	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,Radical_SAM
CMS1_k127_3803024_1	926569.ANT_00880	1.229e-142	468.0	COG0488@1|root,COG0488@2|Bacteria,2G5VD@200795|Chloroflexi	200795|Chloroflexi	S	PFAM ABC transporter related	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
CMS1_k127_3803024_4	926569.ANT_09480	1.203e-68	249.0	COG0237@1|root,COG0237@2|Bacteria,2G6RQ@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
CMS1_k127_3803024_6	479434.Sthe_1865	3.676e-28	126.0	COG1376@1|root,COG5479@1|root,COG1376@2|Bacteria,COG5479@2|Bacteria,2G6ZY@200795|Chloroflexi,27XVB@189775|Thermomicrobia	189775|Thermomicrobia	M	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
CMS1_k127_3803024_5	926550.CLDAP_31420	2.906e-49	188.0	COG0454@1|root,COG0456@2|Bacteria,2G9GA@200795|Chloroflexi	200795|Chloroflexi	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS1_k127_3803024_2	926550.CLDAP_31460	1.538e-96	324.0	COG1216@1|root,COG1216@2|Bacteria,2G5U8@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3
CMS1_k127_3803024_0	926550.CLDAP_31450	6.121e-152	493.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,2G5Y5@200795|Chloroflexi	200795|Chloroflexi	M	PFAM sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
CMS1_k127_3803024_3	926550.CLDAP_07470	7.945e-74	253.0	COG0500@1|root,COG2226@2|Bacteria,2G8EN@200795|Chloroflexi	200795|Chloroflexi	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS1_k127_380611_0	316274.Haur_4114	2.415e-182	632.0	COG2203@1|root,COG3605@1|root,COG5002@1|root,COG2203@2|Bacteria,COG3605@2|Bacteria,COG5002@2|Bacteria,2G7NF@200795|Chloroflexi,374TJ@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS
CMS1_k127_380611_2	926569.ANT_06610	4.621e-37	143.0	COG0745@1|root,COG0745@2|Bacteria,2G986@200795|Chloroflexi	200795|Chloroflexi	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS1_k127_380611_1	926569.ANT_06620	1.83e-56	206.0	COG0596@1|root,COG0596@2|Bacteria,2G8RI@200795|Chloroflexi	200795|Chloroflexi	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CMS1_k127_3819434_5	1128421.JAGA01000002_gene40	1.479e-55	200.0	COG2379@1|root,COG2379@2|Bacteria,2NNQP@2323|unclassified Bacteria	2|Bacteria	G	MOFRL family	-	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
CMS1_k127_3819434_9	395961.Cyan7425_2553	0.0003547	53.0	COG1653@1|root,COG1653@2|Bacteria,1G2MI@1117|Cyanobacteria,3KH7S@43988|Cyanothece	1117|Cyanobacteria	G	Extracellular solute-binding protein, family 1	srrA	-	-	ko:K17244	ko02010,map02010	M00601	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.40	-	-	SBP_bac_1,SBP_bac_8
CMS1_k127_3819434_4	1304880.JAGB01000002_gene1847	2.111e-62	219.0	COG0503@1|root,COG0503@2|Bacteria,1V1BV@1239|Firmicutes,24HGX@186801|Clostridia	186801|Clostridia	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
CMS1_k127_3819434_6	926569.ANT_23120	5.874e-49	187.0	COG3764@1|root,COG3764@2|Bacteria,2G98S@200795|Chloroflexi	200795|Chloroflexi	M	PFAM peptidase C60, sortase A and B	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
CMS1_k127_3819434_8	525904.Tter_0916	4.904e-11	66.0	COG1314@1|root,COG1314@2|Bacteria,2NS1U@2323|unclassified Bacteria	2|Bacteria	U	Preprotein translocase SecG subunit	secG	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
CMS1_k127_3819434_2	926569.ANT_11300	5.666e-117	396.0	COG0747@1|root,COG0747@2|Bacteria,2G5NC@200795|Chloroflexi	200795|Chloroflexi	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_3819434_3	1123252.ATZF01000016_gene1655	2.445e-70	250.0	COG1171@1|root,COG1171@2|Bacteria,1TP22@1239|Firmicutes,4H9NK@91061|Bacilli	91061|Bacilli	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS1_k127_3819434_7	926550.CLDAP_39210	6.576e-29	122.0	COG0824@1|root,COG0824@2|Bacteria,2G9PJ@200795|Chloroflexi	200795|Chloroflexi	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
CMS1_k127_3819434_1	671143.DAMO_2604	1.053e-195	625.0	COG0318@1|root,COG0318@2|Bacteria,2NPH9@2323|unclassified Bacteria	2|Bacteria	IQ	COGs COG0318 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
CMS1_k127_3819434_0	926569.ANT_20890	1.594e-218	687.0	COG0465@1|root,COG0465@2|Bacteria,2G5J3@200795|Chloroflexi	200795|Chloroflexi	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
CMS1_k127_3820046_6	880073.Calab_2491	3.69e-45	172.0	COG0407@1|root,COG0407@2|Bacteria,2NRD5@2323|unclassified Bacteria	2|Bacteria	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
CMS1_k127_3820046_4	292459.STH2499	8.524e-72	263.0	COG2871@1|root,COG3894@1|root,COG2871@2|Bacteria,COG3894@2|Bacteria,1TP0H@1239|Firmicutes,247S0@186801|Clostridia	186801|Clostridia	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
CMS1_k127_3820046_3	697303.Thewi_2118	1.499e-83	291.0	COG0407@1|root,COG0407@2|Bacteria,1V4WM@1239|Firmicutes,24IZV@186801|Clostridia,42J2I@68295|Thermoanaerobacterales	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
CMS1_k127_3820046_5	1125699.HMPREF9194_00243	7.296e-47	174.0	COG0346@1|root,COG0346@2|Bacteria,2J7HC@203691|Spirochaetes	203691|Spirochaetes	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_4
CMS1_k127_3820046_1	391616.OA238_c18300	2.725e-124	406.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,2TRW0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Dehydrogenase E1 component	-	-	-	ko:K21416	-	-	-	-	ko00000,ko01000	-	-	-	E1_dh
CMS1_k127_3820046_0	1382306.JNIM01000001_gene2428	4.832e-174	550.0	COG0022@1|root,COG0022@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	acoB	-	-	ko:K21417	-	-	-	-	ko00000,ko01000	-	-	-	Transket_pyr,Transketolase_C
CMS1_k127_3820046_2	1382306.JNIM01000001_gene2426	4.363e-93	316.0	COG0508@1|root,COG0508@2|Bacteria,2G6A9@200795|Chloroflexi	200795|Chloroflexi	C	Catalytic domain of components of various dehydrogenase complexes	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
CMS1_k127_3821626_3	748224.HMPREF9436_00448	1.312e-54	199.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,249IC@186801|Clostridia,3WGB8@541000|Ruminococcaceae	186801|Clostridia	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_3821626_1	309801.trd_1791	9.595e-133	435.0	COG1092@1|root,COG1092@2|Bacteria,2G5YR@200795|Chloroflexi	200795|Chloroflexi	J	SMART PUA domain containing protein	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
CMS1_k127_3821626_2	477974.Daud_0554	2.447e-110	377.0	COG0323@1|root,COG0323@2|Bacteria,1TPGK@1239|Firmicutes,24902@186801|Clostridia,26042@186807|Peptococcaceae	186801|Clostridia	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
CMS1_k127_3821626_0	1232410.KI421413_gene499	2.577e-227	734.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,42MRR@68525|delta/epsilon subdivisions,2WIQ7@28221|Deltaproteobacteria,43S4R@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	MutS domain I	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
CMS1_k127_3822230_2	1293047.CBMA010000053_gene3289	4.988e-20	96.0	arCOG06227@1|root,arCOG06227@2157|Archaea,2Y0FY@28890|Euryarchaeota,23XYM@183963|Halobacteria	183963|Halobacteria	S	Domain of unknown function (DUF4397)	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3822230_4	1089545.KB913037_gene8436	0.000877	44.0	COG0823@1|root,COG0823@2|Bacteria,2GJET@201174|Actinobacteria,4E7NZ@85010|Pseudonocardiales	201174|Actinobacteria	U	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3822230_3	33898.JRHJ01000078_gene1114	4.516e-05	48.0	COG0823@1|root,COG0823@2|Bacteria,2GJET@201174|Actinobacteria	201174|Actinobacteria	U	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3822230_0	634956.Geoth_3108	1.631e-80	280.0	COG1064@1|root,COG1064@2|Bacteria,1TP5B@1239|Firmicutes,4HA9Z@91061|Bacilli,1WE90@129337|Geobacillus	91061|Bacilli	C	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_3822230_1	398525.KB900701_gene6579	9.751e-64	230.0	COG1893@1|root,COG1893@2|Bacteria,1MX5M@1224|Proteobacteria,2TVRD@28211|Alphaproteobacteria,3K5Z9@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	-	-	-	-	-	-	-	-	-	-	ApbA,ApbA_C
CMS1_k127_3832659_0	1121085.AUCI01000006_gene1587	1.528e-161	512.0	COG3119@1|root,COG3119@2|Bacteria,1VAJC@1239|Firmicutes,4HGBS@91061|Bacilli,1ZGU6@1386|Bacillus	91061|Bacilli	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CMS1_k127_3832659_2	525904.Tter_2607	4.689e-80	276.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
CMS1_k127_3832659_1	1298920.KI911353_gene2753	1.101e-89	312.0	COG1635@1|root,COG1635@2|Bacteria,1UMZ1@1239|Firmicutes,25GSN@186801|Clostridia	186801|Clostridia	H	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
CMS1_k127_3832659_3	1033743.CAES01000040_gene1365	4.926e-59	218.0	COG0673@1|root,COG0673@2|Bacteria,1TQJX@1239|Firmicutes,4HAJ8@91061|Bacilli,26WFD@186822|Paenibacillaceae	91061|Bacilli	S	Oxidoreductase family, NAD-binding Rossmann fold	iolG2	-	1.1.1.18,1.1.1.369	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	-	R01183,R09951	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_3832659_4	1195236.CTER_3262	1.917e-31	136.0	COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,3WH79@541000|Ruminococcaceae	186801|Clostridia	C	Pyruvate formate lyase	-	-	2.3.1.54	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
CMS1_k127_3851197_12	526227.Mesil_0040	2.041e-34	140.0	COG1609@1|root,COG1609@2|Bacteria	2|Bacteria	K	purine nucleotide biosynthetic process	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
CMS1_k127_3851197_4	926550.CLDAP_31040	2.193e-91	311.0	COG1609@1|root,COG1609@2|Bacteria,2G6SK@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
CMS1_k127_3851197_8	330214.NIDE0745	1.384e-61	225.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS1_k127_3851197_17	224911.27356457	1.563e-06	54.0	COG0697@1|root,COG0697@2|Bacteria,1MZQM@1224|Proteobacteria,2TUPG@28211|Alphaproteobacteria,3JW52@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS1_k127_3851197_13	485913.Krac_3536	2.358e-32	132.0	COG3385@1|root,COG3385@2|Bacteria,2G80K@200795|Chloroflexi	2|Bacteria	L	sptr a7nhu5	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5,DDE_Tnp_1
CMS1_k127_3851197_18	420324.KI912059_gene5810	1.983e-05	49.0	COG3385@1|root,COG3385@2|Bacteria,1RK5C@1224|Proteobacteria,2UNB7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
CMS1_k127_3851197_6	665942.HMPREF1022_01975	1.056e-71	268.0	COG1409@1|root,COG1409@2|Bacteria,1QI4K@1224|Proteobacteria,437Q4@68525|delta/epsilon subdivisions,2X2YM@28221|Deltaproteobacteria,2MEM4@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
CMS1_k127_3851197_15	383372.Rcas_2432	2.407e-26	115.0	COG5637@1|root,COG5637@2|Bacteria,2G9J4@200795|Chloroflexi	200795|Chloroflexi	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
CMS1_k127_3851197_14	1122919.KB905611_gene4521	3.834e-32	141.0	COG1397@1|root,COG3401@1|root,COG1397@2|Bacteria,COG3401@2|Bacteria,1UKWI@1239|Firmicutes,4IU1P@91061|Bacilli,277G6@186822|Paenibacillaceae	91061|Bacilli	O	FG-GAP repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3851197_11	344747.PM8797T_10349	5.153e-37	151.0	2DD1P@1|root,2ZG5R@2|Bacteria	2|Bacteria	S	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
CMS1_k127_3851197_7	694429.Pyrfu_1596	2.021e-62	231.0	COG0498@1|root,arCOG01434@2157|Archaea,2XQ1A@28889|Crenarchaeota	28889|Crenarchaeota	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS1_k127_3851197_16	1123065.ATWL01000016_gene1982	8.086e-25	115.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	lmbE	-	-	-	-	-	-	-	-	-	-	-	PIG-L
CMS1_k127_3851197_3	1122223.KB890687_gene2828	3.502e-101	339.0	COG1173@1|root,COG1173@2|Bacteria	2|Bacteria	P	ABC-type dipeptide oligopeptide nickel transport systems, permease components	appC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
CMS1_k127_3851197_2	1122223.KB890687_gene2827	4.803e-103	344.0	COG0601@1|root,COG0601@2|Bacteria,1WIGY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_3851197_0	1122223.KB890687_gene2826	1.872e-156	514.0	COG0747@1|root,COG0747@2|Bacteria	2|Bacteria	E	dipeptide transport	appA	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_3851197_19	765177.Desmu_0356	0.0002845	44.0	COG0498@1|root,arCOG01434@2157|Archaea,2XQ1A@28889|Crenarchaeota	28889|Crenarchaeota	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS1_k127_3851197_1	717605.Theco_0542	1.181e-118	391.0	COG1312@1|root,COG1312@2|Bacteria,1TP5F@1239|Firmicutes,4H9UR@91061|Bacilli,26TTG@186822|Paenibacillaceae	91061|Bacilli	G	D-mannonate dehydratase (UxuA)	-	-	4.2.1.8	ko:K01686	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	UxuA
CMS1_k127_3851197_10	344747.PM8797T_07317	6.012e-53	199.0	COG3608@1|root,COG3608@2|Bacteria,2IYZ6@203682|Planctomycetes	203682|Planctomycetes	S	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	-	-	-	-	-	-	-	-	-	AstE_AspA
CMS1_k127_3851197_5	324602.Caur_3716	6.62e-77	271.0	COG0665@1|root,COG0665@2|Bacteria,2G80C@200795|Chloroflexi,376QJ@32061|Chloroflexia	32061|Chloroflexia	C	PFAM FAD dependent oxidoreductase	-	-	1.5.3.1	ko:K00301	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
CMS1_k127_3851197_9	1122214.AQWH01000005_gene1132	4.338e-56	204.0	COG4689@1|root,COG4689@2|Bacteria	2|Bacteria	Q	acetoacetate decarboxylase activity	adc	-	4.1.1.4	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	M00088	R01366	RC00040	ko00000,ko00001,ko00002,ko01000	-	-	-	ADC
CMS1_k127_3857603_2	316274.Haur_1591	6.478e-46	175.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_3857603_0	452637.Oter_2033	3.853e-123	409.0	COG2268@1|root,COG2268@2|Bacteria,46TRR@74201|Verrucomicrobia,3K887@414999|Opitutae	414999|Opitutae	S	prohibitin homologues	-	-	-	ko:K07192	ko04910,map04910	-	-	-	ko00000,ko00001,ko03036,ko04131,ko04147	-	-	-	Band_7
CMS1_k127_3857603_3	667014.Thein_2196	3.485e-37	144.0	COG0174@1|root,COG0174@2|Bacteria,2GH5N@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	Glutamine synthetase, catalytic domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
CMS1_k127_3864474_5	926550.CLDAP_17520	5.757e-16	86.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS1_k127_3864474_3	671143.DAMO_2439	2.17e-38	153.0	COG2197@1|root,COG2202@1|root,COG2197@2|Bacteria,COG2202@2|Bacteria	2|Bacteria	T	Pas domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF_2,GGDEF,GerE,HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,Response_reg
CMS1_k127_3864474_0	926550.CLDAP_32730	1.011e-214	676.0	COG5598@1|root,COG5598@2|Bacteria	2|Bacteria	H	trimethylamine methyltransferase	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
CMS1_k127_3864474_4	1379698.RBG1_1C00001G0052	6.359e-38	150.0	COG1150@1|root,COG1150@2|Bacteria,2NQ2K@2323|unclassified Bacteria	2|Bacteria	C	4Fe-4S dicluster domain	hdrC	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389,ko:K03390,ko:K16887,ko:K18930	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3424	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17,Fer4_7,Fer4_8,Fer4_9
CMS1_k127_3864474_2	1379698.RBG1_1C00001G0051	4.135e-77	269.0	COG2048@1|root,COG2048@2|Bacteria,2NQP7@2323|unclassified Bacteria	2|Bacteria	C	Heterodisulfide reductase subunit B	hdrB	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
CMS1_k127_3864474_1	1121440.AUMA01000003_gene3114	5.431e-201	636.0	COG1148@1|root,COG1148@2|Bacteria,1QUMN@1224|Proteobacteria,43BMA@68525|delta/epsilon subdivisions,2X6ZG@28221|Deltaproteobacteria,2M898@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,FlpD,Pyr_redox_2
CMS1_k127_3864742_0	926550.CLDAP_22510	1.219e-282	876.0	COG0488@1|root,COG0488@2|Bacteria	2|Bacteria	L	(ABC) transporter	yjjK	GO:0003674,GO:0003824,GO:0005488,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113	3.6.3.25	ko:K06020	-	-	-	-	ko00000,ko01000	-	-	-	ABC_tran,ABC_tran_Xtn
CMS1_k127_3864742_8	309807.SRU_0831	1.161e-28	122.0	2E7ZG@1|root,332DV@2|Bacteria,4P625@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF4864)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4864
CMS1_k127_3864742_5	1189619.pgond44_08976	8.478e-49	184.0	COG1028@1|root,COG1028@2|Bacteria,4NEAI@976|Bacteroidetes,1HXDZ@117743|Flavobacteriia,4C2UK@83612|Psychroflexus	976|Bacteroidetes	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS1_k127_3864742_4	446471.Xcel_1604	1.173e-54	203.0	COG0500@1|root,COG2226@2|Bacteria,2IA9Q@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS1_k127_3864742_3	357808.RoseRS_1495	4.386e-80	272.0	COG4977@1|root,COG4977@2|Bacteria,2GA7K@200795|Chloroflexi,377NZ@32061|Chloroflexia	32061|Chloroflexia	K	PFAM ThiJ PfpI domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
CMS1_k127_3864742_6	391037.Sare_0104	1.263e-47	179.0	COG1309@1|root,COG1309@2|Bacteria,2GQRD@201174|Actinobacteria,4DBTU@85008|Micromonosporales	201174|Actinobacteria	K	Tetracycline repressor protein class H	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C,TetR_N
CMS1_k127_3864742_1	1173024.KI912151_gene1879	2.37e-154	492.0	COG1028@1|root,COG1028@2|Bacteria,1G02R@1117|Cyanobacteria,1JK3B@1189|Stigonemataceae	1117|Cyanobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS1_k127_3864742_2	357808.RoseRS_3864	8.155e-105	351.0	COG3616@1|root,COG3616@2|Bacteria,2G69D@200795|Chloroflexi	200795|Chloroflexi	E	PFAM alanine racemase domain protein	-	-	4.3.1.27	ko:K20757	-	-	-	-	ko00000,ko01000	-	-	-	Ala_racemase_N,D-ser_dehydrat
CMS1_k127_3864742_7	926550.CLDAP_01300	7.778e-37	143.0	COG0071@1|root,COG0071@2|Bacteria,2G71M@200795|Chloroflexi	200795|Chloroflexi	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
CMS1_k127_3868126_8	313624.NSP_50120	4.486e-17	90.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	2.1.1.163,2.1.1.201	ko:K03183,ko:K15256	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
CMS1_k127_3868126_11	1536773.R70331_09790	1.208e-05	60.0	COG1361@1|root,COG1361@2|Bacteria,1V4V3@1239|Firmicutes,4HT0D@91061|Bacilli,26QKX@186822|Paenibacillaceae	91061|Bacilli	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
CMS1_k127_3868126_0	1121481.AUAS01000011_gene4944	2.134e-246	829.0	COG2931@1|root,COG2931@2|Bacteria,4NKIR@976|Bacteroidetes,47S7V@768503|Cytophagia	976|Bacteroidetes	Q	SMART Integrin alpha beta-propellor repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,FG-GAP,HYR,VCBS
CMS1_k127_3868126_5	1121472.AQWN01000008_gene2021	1.261e-59	222.0	COG0438@1|root,COG0438@2|Bacteria,1TQ1S@1239|Firmicutes,24GPH@186801|Clostridia,260YH@186807|Peptococcaceae	186801|Clostridia	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
CMS1_k127_3868126_6	1304880.JAGB01000002_gene1888	1.702e-46	182.0	COG0438@1|root,COG0438@2|Bacteria,1TPS8@1239|Firmicutes,25ESM@186801|Clostridia	186801|Clostridia	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS1_k127_3868126_9	936455.KI421499_gene4986	1.726e-16	91.0	COG0438@1|root,COG0438@2|Bacteria,1Q7RK@1224|Proteobacteria,2VDX3@28211|Alphaproteobacteria,3K4ZE@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3868126_7	82654.Pse7367_2693	1.373e-42	170.0	COG4122@1|root,COG4122@2|Bacteria	2|Bacteria	E	O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24,TylF
CMS1_k127_3868126_3	316274.Haur_0234	1.245e-107	360.0	COG0438@1|root,COG0438@2|Bacteria,2G7TE@200795|Chloroflexi,3750Z@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	2.4.1.348	ko:K12995	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glyco_transf_4,Glycos_transf_1
CMS1_k127_3868126_2	926550.CLDAP_10360	9.169e-117	419.0	COG0457@1|root,COG3307@1|root,COG0457@2|Bacteria,COG3307@2|Bacteria,2G81B@200795|Chloroflexi	200795|Chloroflexi	M	-O-antigen	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,Wzy_C
CMS1_k127_3868126_4	357808.RoseRS_4524	5.544e-99	333.0	COG0472@1|root,COG0472@2|Bacteria,2G7WQ@200795|Chloroflexi,375BA@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase family 4	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
CMS1_k127_3868126_1	756499.Desde_3865	1.202e-150	488.0	COG0677@1|root,COG0677@2|Bacteria,1TPXY@1239|Firmicutes,248NW@186801|Clostridia,2606B@186807|Peptococcaceae	186801|Clostridia	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.136	ko:K13015	ko00520,map00520	-	R00421	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
CMS1_k127_3868126_10	1123508.JH636439_gene566	1.339e-08	56.0	COG0039@1|root,COG0039@2|Bacteria,2IX99@203682|Planctomycetes	203682|Planctomycetes	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
CMS1_k127_3869679_2	1157638.KB892180_gene3903	3.757e-43	166.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria	201174|Actinobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS1_k127_3869679_4	1205908.AKXW01000105_gene1298	7.402e-16	81.0	COG2197@1|root,COG2197@2|Bacteria,1Q7GF@1224|Proteobacteria,1RWWU@1236|Gammaproteobacteria,1XUUA@135623|Vibrionales	135623|Vibrionales	K	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	narP	-	-	ko:K07685	ko02020,map02020	M00472	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
CMS1_k127_3869679_3	768704.Desmer_2528	9.514e-20	102.0	COG4585@1|root,COG4585@2|Bacteria,1TQI3@1239|Firmicutes,249R9@186801|Clostridia,260T5@186807|Peptococcaceae	186801|Clostridia	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	degS	-	2.7.13.3	ko:K07777	ko02020,map02020	M00478	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DegS,HATPase_c,HisKA_3
CMS1_k127_3869679_1	1207063.P24_01155	3.612e-99	336.0	COG0477@1|root,COG2814@2|Bacteria,1Q613@1224|Proteobacteria,2VCA0@28211|Alphaproteobacteria,2JY9G@204441|Rhodospirillales	204441|Rhodospirillales	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_3869679_0	479434.Sthe_1742	0.0	1394.0	COG4447@1|root,COG4447@2|Bacteria,2G678@200795|Chloroflexi,27YSS@189775|Thermomicrobia	189775|Thermomicrobia	S	PFAM glycosyl hydrolase BNR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CMS1_k127_3869679_5	1122997.AUDD01000002_gene1078	1.273e-07	55.0	COG1247@1|root,COG1247@2|Bacteria,2I3CR@201174|Actinobacteria	201174|Actinobacteria	M	GCN5 family acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS1_k127_3879382_5	314230.DSM3645_10437	1.429e-32	136.0	COG2159@1|root,COG2159@2|Bacteria,2IZB9@203682|Planctomycetes	203682|Planctomycetes	S	metal-dependent hydrolase of the TIM-barrel fold	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
CMS1_k127_3879382_3	382464.ABSI01000010_gene3529	1.194e-51	193.0	COG2159@1|root,COG2159@2|Bacteria,46T6W@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CMS1_k127_3879382_0	439235.Dalk_0629	2.594e-105	356.0	COG0001@1|root,COG1861@1|root,COG0001@2|Bacteria,COG1861@2|Bacteria,1MUY5@1224|Proteobacteria,42NVU@68525|delta/epsilon subdivisions,2WMH6@28221|Deltaproteobacteria,2MNBA@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Aminotransferase class-III	-	-	2.6.1.111,5.4.3.8	ko:K01845,ko:K07257,ko:K21585	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272,R11607	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3,CTP_transf_3
CMS1_k127_3879382_1	1002809.SSIL_0505	1.041e-65	236.0	COG0395@1|root,COG0395@2|Bacteria,1UY7D@1239|Firmicutes,4HCWU@91061|Bacilli,26F8I@186818|Planococcaceae	91061|Bacilli	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026,ko:K10242	ko02010,map02010	M00206,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.23	-	-	BPD_transp_1
CMS1_k127_3879382_2	1227487.C474_07297	2.802e-65	234.0	COG1175@1|root,arCOG00157@2157|Archaea,2XVCF@28890|Euryarchaeota,23UMK@183963|Halobacteria	183963|Halobacteria	P	COG1175 ABC-type sugar transport systems, permease components	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_3879382_4	521045.Kole_0679	3.917e-50	195.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
CMS1_k127_3879382_6	909663.KI867150_gene1043	1.695e-22	98.0	COG0348@1|root,COG1143@1|root,COG1245@1|root,COG0348@2|Bacteria,COG1143@2|Bacteria,COG1245@2|Bacteria,1QW0T@1224|Proteobacteria,43BQQ@68525|delta/epsilon subdivisions,2X71S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5
CMS1_k127_388660_2	344747.PM8797T_30556	9.509e-21	93.0	COG4221@1|root,COG4221@2|Bacteria,2IYVR@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS1_k127_388660_4	1173022.Cri9333_0583	0.0006594	53.0	COG1337@1|root,COG1337@2|Bacteria,1G2X8@1117|Cyanobacteria,1HA6E@1150|Oscillatoriales	1117|Cyanobacteria	L	RAMP superfamily	-	-	-	-	-	-	-	-	-	-	-	-	RAMPs
CMS1_k127_388660_0	945713.IALB_1809	2.665e-127	414.0	COG0863@1|root,COG0863@2|Bacteria	2|Bacteria	L	N-4 methylation of cytosine	-	-	2.1.1.72	ko:K00571,ko:K03497	-	-	-	-	ko00000,ko01000,ko02048,ko03000,ko03036,ko04812	-	-	-	N6_N4_Mtase,ParBc,RE_Eco29kI
CMS1_k127_388660_3	1123057.P872_05035	1.045e-06	59.0	COG5061@1|root,COG5061@2|Bacteria,4NJWC@976|Bacteroidetes,47Q6M@768503|Cytophagia	976|Bacteroidetes	OU	Protein of unknown function (DUF3307)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3307
CMS1_k127_388660_1	102129.Lepto7375DRAFT_8119	2.366e-43	165.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria	1117|Cyanobacteria	Q	Amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
CMS1_k127_3887081_7	1173024.KI912151_gene2428	1.127e-19	91.0	2B766@1|root,3207Z@2|Bacteria,1G9KP@1117|Cyanobacteria,1JMIJ@1189|Stigonemataceae	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3887081_6	28072.Nos7524_3874	8.768e-29	118.0	2CUP7@1|root,32SVQ@2|Bacteria,1G747@1117|Cyanobacteria,1HPEJ@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3887081_11	591158.SSMG_01276	9.088e-09	59.0	COG1396@1|root,COG1396@2|Bacteria,2GPWH@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3,HTH_31
CMS1_k127_3887081_1	1396141.BATP01000057_gene3053	3.354e-139	478.0	COG2312@1|root,COG3209@1|root,COG2312@2|Bacteria,COG3209@2|Bacteria,46XD5@74201|Verrucomicrobia,2IVHX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Fn3_assoc,LTD
CMS1_k127_3887081_8	1122179.KB890435_gene931	1.403e-15	92.0	COG5337@1|root,COG5337@2|Bacteria,4NI4U@976|Bacteroidetes	976|Bacteroidetes	M	COG5337 Spore coat assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH,LTD
CMS1_k127_3887081_3	926550.CLDAP_01930	4.123e-78	289.0	COG4713@1|root,COG4713@2|Bacteria,2GA9E@200795|Chloroflexi	2|Bacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2142
CMS1_k127_3887081_9	926550.CLDAP_07440	7.225e-13	83.0	COG4713@1|root,COG4713@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2142
CMS1_k127_3887081_5	1128421.JAGA01000002_gene78	5.757e-34	153.0	COG1928@1|root,COG1928@2|Bacteria	2|Bacteria	O	C-terminal four TMM region of protein-O-mannosyltransferase	-	-	2.4.1.109	ko:K00728	ko00514,ko00515,ko01100,map00514,map00515,map01100	-	R04072,R07620,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003	-	GT39	-	PMT,PMT_2,PMT_4TMC
CMS1_k127_3887081_10	357808.RoseRS_0394	1.5e-10	74.0	COG1807@1|root,COG1807@2|Bacteria,2G8DG@200795|Chloroflexi	200795|Chloroflexi	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS1_k127_3887081_4	357808.RoseRS_2179	3.41e-75	267.0	COG0438@1|root,COG0438@2|Bacteria,2G6AR@200795|Chloroflexi,376SQ@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CMS1_k127_3887081_2	1128421.JAGA01000004_gene2539	9.322e-82	282.0	COG1216@1|root,COG1216@2|Bacteria,2NP9Z@2323|unclassified Bacteria	2|Bacteria	GM	Glycosyltransferase like family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
CMS1_k127_3887081_0	316274.Haur_0489	2.416e-157	516.0	COG3591@1|root,COG4412@1|root,COG3591@2|Bacteria,COG4412@2|Bacteria,2GB3W@200795|Chloroflexi,377V9@32061|Chloroflexia	32061|Chloroflexia	E	PFAM von Willebrand factor type A	-	-	3.4.21.50	ko:K01337	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	VWA
CMS1_k127_3888757_5	243231.GSU2823	6.534e-23	106.0	COG1566@1|root,COG1566@2|Bacteria,1QU7Z@1224|Proteobacteria,43BPM@68525|delta/epsilon subdivisions,2X70W@28221|Deltaproteobacteria,43TJU@69541|Desulfuromonadales	28221|Deltaproteobacteria	V	HlyD membrane-fusion protein of T1SS	ybhG	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
CMS1_k127_3888757_6	926550.CLDAP_25490	9.98e-07	58.0	COG0265@1|root,COG3103@1|root,COG0265@2|Bacteria,COG4991@2|Bacteria,2G821@200795|Chloroflexi	200795|Chloroflexi	O	Trypsin	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	Trypsin_2
CMS1_k127_3888757_2	671143.DAMO_0007	8.992e-73	261.0	COG0265@1|root,COG0265@2|Bacteria,2NQPN@2323|unclassified Bacteria	2|Bacteria	O	Trypsin	degP	-	1.3.1.74	ko:K08070,ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
CMS1_k127_3888757_4	489825.LYNGBM3L_10620	3.895e-42	167.0	COG3315@1|root,COG3315@2|Bacteria,1G5DY@1117|Cyanobacteria,1HFS2@1150|Oscillatoriales	1117|Cyanobacteria	H	Leucine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	LCM
CMS1_k127_3888757_1	926550.CLDAP_06510	1.264e-81	281.0	COG1319@1|root,COG1319@2|Bacteria,2G8QI@200795|Chloroflexi	200795|Chloroflexi	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
CMS1_k127_3888757_3	926550.CLDAP_06500	1.257e-61	241.0	COG2080@1|root,COG2080@2|Bacteria,2G6NT@200795|Chloroflexi	200795|Chloroflexi	C	2Fe-2S -binding domain protein	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
CMS1_k127_3888757_0	926550.CLDAP_06490	8.166e-308	970.0	COG1529@1|root,COG1529@2|Bacteria,2G65D@200795|Chloroflexi	200795|Chloroflexi	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
CMS1_k127_3896537_5	40571.JOEA01000022_gene7033	0.0005953	46.0	COG2182@1|root,COG2182@2|Bacteria,2I3U6@201174|Actinobacteria,4EFDF@85010|Pseudonocardiales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
CMS1_k127_3896537_3	525904.Tter_2500	1.527e-108	359.0	COG0395@1|root,COG0395@2|Bacteria	2|Bacteria	P	glycerophosphodiester transmembrane transport	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
CMS1_k127_3896537_1	525904.Tter_2501	5.043e-118	387.0	COG1175@1|root,COG1175@2|Bacteria	2|Bacteria	P	transmembrane transport	-	-	-	ko:K02025,ko:K05814,ko:K10118,ko:K10237,ko:K10241,ko:K15771,ko:K17235,ko:K17316	ko02010,map02010	M00196,M00198,M00204,M00206,M00207,M00491,M00602,M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.17,3.A.1.1.2,3.A.1.1.23,3.A.1.1.24,3.A.1.1.28,3.A.1.1.3,3.A.1.1.30,3.A.1.1.34	-	-	BPD_transp_1
CMS1_k127_3896537_0	525904.Tter_2502	8.544e-155	501.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
CMS1_k127_3896537_4	525904.Tter_2503	8.249e-71	251.0	COG1609@1|root,COG1609@2|Bacteria	2|Bacteria	K	purine nucleotide biosynthetic process	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
CMS1_k127_3896537_2	1205680.CAKO01000038_gene1796	4.692e-116	382.0	COG5476@1|root,COG5476@2|Bacteria,1MX4P@1224|Proteobacteria,2TS1C@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1485,MlrC_C
CMS1_k127_3897654_3	383372.Rcas_1479	1.357e-58	211.0	COG0515@1|root,COG0515@2|Bacteria,2GBWC@200795|Chloroflexi,375DM@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS1_k127_3897654_4	323259.Mhun_2111	3.485e-22	100.0	COG2402@1|root,arCOG04502@2157|Archaea	2157|Archaea	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07065	-	-	-	-	ko00000	-	-	-	PIN
CMS1_k127_3897654_5	643648.Slip_2302	0.0007066	46.0	2BB3M@1|root,324JW@2|Bacteria,1UQUE@1239|Firmicutes,258KT@186801|Clostridia,42KWX@68298|Syntrophomonadaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3897654_2	1128421.JAGA01000002_gene1688	5.168e-70	246.0	COG3118@1|root,COG3118@2|Bacteria	2|Bacteria	O	belongs to the thioredoxin family	-	-	-	ko:K03671,ko:K05838	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
CMS1_k127_3897654_0	237368.SCABRO_00607	3.845e-128	419.0	COG0707@1|root,COG0707@2|Bacteria	2|Bacteria	M	undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C,Glyco_trans_1_3
CMS1_k127_3897654_1	926550.CLDAP_34850	1.988e-115	376.0	COG0647@1|root,COG0647@2|Bacteria,2G60W@200795|Chloroflexi	200795|Chloroflexi	G	COGs COG0647 sugar phosphatase of the HAD superfamily	-	-	-	ko:K02566	-	-	-	-	ko00000	-	-	-	Hydrolase_6,Hydrolase_like
CMS1_k127_3898765_1	926550.CLDAP_02120	5.874e-49	187.0	COG3534@1|root,COG3534@2|Bacteria	2|Bacteria	G	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_44,Glyco_hydro_cc,Laminin_G_3,PA14
CMS1_k127_3898765_0	1128421.JAGA01000002_gene1114	5.044e-118	394.0	COG1134@1|root,COG1134@2|Bacteria,2NP4S@2323|unclassified Bacteria	2|Bacteria	GM	ATPases associated with a variety of cellular activities	-	-	3.6.3.38	ko:K01990,ko:K09689,ko:K09691	ko02010,map02010	M00249,M00250,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.101,3.A.1.103	-	-	ABC_tran,Wzt_C
CMS1_k127_3898765_2	234267.Acid_5620	3.999e-26	118.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.1.1.294,2.7.1.181	ko:K18827	-	-	R10657,R10658	RC00002,RC00003,RC00078,RC03220	ko00000,ko01000,ko01005	-	-	-	DUF4214,Glycos_transf_2,Methyltransf_11,Methyltransf_21,Methyltransf_23,Methyltransf_25
CMS1_k127_3900865_4	235909.GK2085	8.632e-18	96.0	COG3385@1|root,COG3385@2|Bacteria,1V8EV@1239|Firmicutes,4HK4P@91061|Bacilli,1WFE0@129337|Geobacillus	91061|Bacilli	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5,DDE_Tnp_1
CMS1_k127_3900865_2	1156935.QWE_15192	2.037e-110	365.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,2TTEV@28211|Alphaproteobacteria,4B88T@82115|Rhizobiaceae	28211|Alphaproteobacteria	EP	ABC-type dipeptide oligopeptide nickel transport systems, permease components	MA20_20685	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
CMS1_k127_3900865_0	383372.Rcas_2022	6.517e-174	553.0	COG1473@1|root,COG1473@2|Bacteria,2G7D3@200795|Chloroflexi,375H2@32061|Chloroflexia	32061|Chloroflexia	S	peptidase dimerisation domain protein	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
CMS1_k127_3900865_3	99598.Cal7507_3216	1.011e-94	318.0	COG1028@1|root,COG1028@2|Bacteria,1G67A@1117|Cyanobacteria,1HP1Q@1161|Nostocales	1117|Cyanobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS1_k127_3900865_1	869210.Marky_1959	3.99e-112	370.0	COG0109@1|root,COG1612@1|root,COG0109@2|Bacteria,COG1612@2|Bacteria,1WIAB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	COX15-CtaA,UbiA
CMS1_k127_3908392_10	309801.trd_0523	1.785e-12	70.0	COG3842@1|root,COG3842@2|Bacteria,2G62V@200795|Chloroflexi,27XG2@189775|Thermomicrobia	189775|Thermomicrobia	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
CMS1_k127_3908392_1	309801.trd_0522	1.468e-96	323.0	COG1176@1|root,COG1176@2|Bacteria,2G6E0@200795|Chloroflexi,27XNS@189775|Thermomicrobia	189775|Thermomicrobia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
CMS1_k127_3908392_3	383372.Rcas_2838	1.359e-79	277.0	COG1177@1|root,COG1177@2|Bacteria,2G6DH@200795|Chloroflexi,375E6@32061|Chloroflexia	32061|Chloroflexia	E	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
CMS1_k127_3908392_2	309801.trd_0520	3.446e-94	322.0	COG0687@1|root,COG0687@2|Bacteria,2G6U4@200795|Chloroflexi,27XZQ@189775|Thermomicrobia	189775|Thermomicrobia	E	Bacterial extracellular solute-binding protein	-	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_8
CMS1_k127_3908392_4	1128421.JAGA01000001_gene2083	1.61e-64	232.0	COG1475@1|root,COG1475@2|Bacteria,2NS1X@2323|unclassified Bacteria	2|Bacteria	K	DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF4032,ParBc
CMS1_k127_3908392_0	926550.CLDAP_39300	3.062e-114	397.0	COG1305@1|root,COG1305@2|Bacteria,2G66M@200795|Chloroflexi	200795|Chloroflexi	E	PFAM transglutaminase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129,Transglut_core
CMS1_k127_3908392_7	373903.Hore_03090	3.409e-26	115.0	COG0622@1|root,COG0622@2|Bacteria,1VA0U@1239|Firmicutes,24MMK@186801|Clostridia,3WAYI@53433|Halanaerobiales	186801|Clostridia	S	TIGRFAM phosphoesterase, MJ0936 family	yfcE1	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
CMS1_k127_3908392_8	907931.AEIZ01000003_gene440	5.897e-21	106.0	COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,4H9SR@91061|Bacilli,4AX7D@81850|Leuconostocaceae	91061|Bacilli	S	AI-2E family transporter	yueF	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
CMS1_k127_3908392_6	926550.CLDAP_10530	2.193e-29	138.0	COG0457@1|root,COG0823@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,2G8PZ@200795|Chloroflexi	200795|Chloroflexi	U	WD40 domain protein beta Propeller	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
CMS1_k127_3908392_9	529818.AMSG_12136T0	6.368e-13	82.0	COG1524@1|root,KOG2126@2759|Eukaryota	2759|Eukaryota	U	mannose-ethanolamine phosphotransferase activity	-	-	-	ko:K05288	ko00563,ko01100,map00563,map01100	-	R05923,R08107	RC00017	ko00000,ko00001	-	-	-	Phosphodiest
CMS1_k127_3908392_5	357808.RoseRS_1416	1.971e-37	144.0	COG1091@1|root,COG1091@2|Bacteria,2G6NS@200795|Chloroflexi,375G0@32061|Chloroflexia	32061|Chloroflexia	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
CMS1_k127_3910973_7	665571.STHERM_c20580	1.46e-08	68.0	COG3934@1|root,COG3934@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.78	ko:K19355	ko00051,map00051	-	R01332	RC00467	ko00000,ko00001,ko01000	-	-	-	Cellulase,DUF5060
CMS1_k127_3910973_5	661478.OP10G_1083	1.928e-17	98.0	COG3934@1|root,COG3934@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.78	ko:K19355	ko00051,map00051	-	R01332	RC00467	ko00000,ko00001,ko01000	-	-	-	Cellulase,DUF5060
CMS1_k127_3910973_4	1122135.KB893157_gene123	1.268e-48	183.0	COG0279@1|root,COG0279@2|Bacteria,1R8MP@1224|Proteobacteria,2VF1N@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
CMS1_k127_3910973_1	926550.CLDAP_36250	1.211e-141	468.0	COG1032@1|root,COG1032@2|Bacteria,2G5SI@200795|Chloroflexi	200795|Chloroflexi	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
CMS1_k127_3910973_6	637905.SVI_1347	1.112e-10	64.0	COG3311@1|root,COG3311@2|Bacteria,1N72I@1224|Proteobacteria,1SDJ2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Excisionase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
CMS1_k127_3910973_0	926550.CLDAP_36250	2.826e-246	770.0	COG1032@1|root,COG1032@2|Bacteria,2G5SI@200795|Chloroflexi	200795|Chloroflexi	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
CMS1_k127_3910973_2	357808.RoseRS_4222	2.552e-134	440.0	COG0463@1|root,COG0463@2|Bacteria,2G7KQ@200795|Chloroflexi,376XJ@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS1_k127_3910973_3	926550.CLDAP_36270	7.771e-99	328.0	COG0110@1|root,COG0110@2|Bacteria,2G6D2@200795|Chloroflexi	200795|Chloroflexi	S	PFAM transferase hexapeptide repeat containing protein	-	-	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2
CMS1_k127_3913773_2	323850.Shew_3239	5.687e-52	194.0	COG2373@1|root,COG3055@1|root,COG3386@1|root,COG2373@2|Bacteria,COG3055@2|Bacteria,COG3386@2|Bacteria,1N85X@1224|Proteobacteria,1T3ZR@1236|Gammaproteobacteria,2QEVC@267890|Shewanellaceae	1224|Proteobacteria	M	PFAM Na-Ca exchanger integrin-beta4	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3913773_0	446470.Snas_0537	3.812e-205	681.0	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Kelch_1,Kelch_3,Kelch_6
CMS1_k127_3913773_1	945713.IALB_1068	8.411e-60	237.0	COG1022@1|root,COG1022@2|Bacteria	2|Bacteria	I	Amp-dependent synthetase and ligase	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
CMS1_k127_3913773_3	357808.RoseRS_0608	3.538e-29	120.0	COG4097@1|root,COG4097@2|Bacteria,2G71Y@200795|Chloroflexi,375FI@32061|Chloroflexia	32061|Chloroflexia	P	Ferric reductase like transmembrane component	-	-	-	-	-	-	-	-	-	-	-	-	Ferric_reduct
CMS1_k127_3918819_2	926550.CLDAP_17420	6.413e-157	502.0	COG1331@1|root,COG1331@2|Bacteria,2G5R1@200795|Chloroflexi	200795|Chloroflexi	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
CMS1_k127_3918819_7	525904.Tter_0247	5.759e-12	78.0	COG3794@1|root,COG3794@2|Bacteria,2NRPQ@2323|unclassified Bacteria	2|Bacteria	C	blue (type 1) copper	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cupredoxin_1
CMS1_k127_3918819_5	926550.CLDAP_26340	7.315e-18	98.0	COG1572@1|root,COG3292@1|root,COG1572@2|Bacteria,COG3292@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	BNR_assoc_N,Beta_helix,CARDB,Cleaved_Adhesin,DUF4465,Glyco_tran_WbsX,fn3
CMS1_k127_3918819_6	1089545.KB913037_gene8972	2.395e-14	87.0	COG3794@1|root,COG3794@2|Bacteria,2H73G@201174|Actinobacteria,4E2Z7@85010|Pseudonocardiales	201174|Actinobacteria	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
CMS1_k127_3918819_8	631362.Thi970DRAFT_05009	1.68e-09	59.0	COG4584@1|root,COG4584@2|Bacteria,1MW5J@1224|Proteobacteria	1224|Proteobacteria	L	COG4584 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	rve
CMS1_k127_3918819_4	1128421.JAGA01000002_gene1099	5.938e-42	161.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	M1-584	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS1_k127_3918819_0	255470.cbdbA1049	5.307e-202	644.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,2G8XD@200795|Chloroflexi,34CY9@301297|Dehalococcoidia	301297|Dehalococcoidia	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
CMS1_k127_3918819_3	926550.CLDAP_09720	3.707e-81	274.0	COG3707@1|root,COG3707@2|Bacteria,2G6CD@200795|Chloroflexi	200795|Chloroflexi	T	PFAM response regulator receiver	-	-	-	ko:K22010	-	M00839	-	-	ko00000,ko00002,ko02022	-	-	-	ANTAR,Response_reg
CMS1_k127_3918819_1	649638.Trad_1838	1.245e-170	556.0	COG0747@1|root,COG0747@2|Bacteria,1WMAS@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	ABC-type dipeptide transport system periplasmic component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_3918916_1	926569.ANT_29680	7.289e-245	772.0	COG1132@1|root,COG1132@2|Bacteria,2G66A@200795|Chloroflexi	200795|Chloroflexi	V	ABC transporter, transmembrane region	-	-	-	ko:K06147,ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS1_k127_3918916_0	926569.ANT_29670	1.135e-248	781.0	COG1132@1|root,COG1132@2|Bacteria,2G5QH@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS1_k127_3918916_4	926550.CLDAP_17130	1.789e-68	249.0	COG4856@1|root,COG4856@2|Bacteria,2G75D@200795|Chloroflexi	200795|Chloroflexi	S	PFAM YbbR family protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
CMS1_k127_3918916_3	1382356.JQMP01000004_gene72	7.624e-70	246.0	COG1624@1|root,COG1624@2|Bacteria,2G6J7@200795|Chloroflexi,27XJ7@189775|Thermomicrobia	189775|Thermomicrobia	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	-	-	-	-	-	-	-	-	-	-	DisA_N
CMS1_k127_3918916_5	5932.XP_004035250.1	8.232e-08	66.0	COG3914@1|root,COG5069@1|root,KOG0516@2759|Eukaryota,KOG4626@2759|Eukaryota,3ZB2N@5878|Ciliophora	5878|Ciliophora	GOT	Encoded by	-	-	-	ko:K17560	-	-	-	-	ko00000,ko01009	-	-	-	TPR_1,TPR_2,TPR_8
CMS1_k127_3918916_6	1288494.EBAPG3_26680	0.0001435	55.0	COG0457@1|root,COG0457@2|Bacteria,1RJT4@1224|Proteobacteria,2VSH2@28216|Betaproteobacteria,373XQ@32003|Nitrosomonadales	28216|Betaproteobacteria	S	LytR cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,TPR_1,TPR_2,TPR_8
CMS1_k127_3918916_2	926569.ANT_18090	1.648e-112	371.0	COG0078@1|root,COG0078@2|Bacteria,2G5Z9@200795|Chloroflexi	200795|Chloroflexi	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
CMS1_k127_3920877_11	1047013.AQSP01000128_gene457	1.248e-38	148.0	COG2848@1|root,COG2848@2|Bacteria,2NPVH@2323|unclassified Bacteria	2|Bacteria	S	Uncharacterised ACR (DUF711)	-	-	-	ko:K09157	-	-	-	-	ko00000	-	-	-	DUF711
CMS1_k127_3920877_2	96561.Dole_1175	4.379e-100	342.0	COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,42MET@68525|delta/epsilon subdivisions,2WITH@28221|Deltaproteobacteria,2MHR7@213118|Desulfobacterales	28221|Deltaproteobacteria	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	algC	-	5.4.2.2,5.4.2.8	ko:K01840,ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
CMS1_k127_3920877_4	1121403.AUCV01000054_gene2598	3.987e-93	310.0	COG2220@1|root,COG2220@2|Bacteria,1PFZZ@1224|Proteobacteria,42SXY@68525|delta/epsilon subdivisions,2WPFM@28221|Deltaproteobacteria,2MMG4@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
CMS1_k127_3920877_9	1174528.JH992898_gene3086	2.493e-60	225.0	COG2211@1|root,COG2211@2|Bacteria,1G0JI@1117|Cyanobacteria,1JGSJ@1189|Stigonemataceae	1117|Cyanobacteria	G	PUCC protein	pucC	-	-	ko:K08226	-	-	-	-	ko00000,ko02000	2.A.1.41	-	-	PUCC
CMS1_k127_3920877_12	706587.Desti_2713	4.834e-17	87.0	COG0745@1|root,COG0745@2|Bacteria	706587.Desti_2713|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3920877_13	926569.ANT_02090	3.943e-15	83.0	29Z2W@1|root,30M0E@2|Bacteria,2G9IN@200795|Chloroflexi	200795|Chloroflexi	S	Family of unknown function (DUF5317)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5317
CMS1_k127_3920877_6	926569.ANT_04770	1.33e-81	306.0	COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,2G6RU@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12
CMS1_k127_3920877_10	326427.Cagg_1904	4.245e-53	196.0	COG0500@1|root,COG2226@2|Bacteria,2G6N8@200795|Chloroflexi,375GC@32061|Chloroflexia	32061|Chloroflexia	Q	Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS1_k127_3920877_5	1499967.BAYZ01000103_gene3745	5.922e-92	316.0	COG0013@1|root,COG0013@2|Bacteria,2NPQB@2323|unclassified Bacteria	2|Bacteria	J	Threonyl and Alanyl tRNA synthetase second additional domain	alaS_2	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
CMS1_k127_3920877_14	1499967.BAYZ01000009_gene5334	1.793e-11	67.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_4,PAS_9,PocR
CMS1_k127_3920877_3	926550.CLDAP_09860	1.705e-94	321.0	COG2035@1|root,COG2035@2|Bacteria,2G6J1@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF368)	-	-	-	ko:K08974	-	-	-	-	ko00000	-	-	-	DUF368
CMS1_k127_3920877_0	926550.CLDAP_02810	1.763e-231	730.0	COG0465@1|root,COG0465@2|Bacteria,2G5J3@200795|Chloroflexi	200795|Chloroflexi	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
CMS1_k127_3920877_8	926569.ANT_06590	2.182e-66	236.0	COG2199@1|root,COG3706@2|Bacteria,2G85T@200795|Chloroflexi	200795|Chloroflexi	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
CMS1_k127_3920877_1	479434.Sthe_2769	1.827e-136	446.0	COG0612@1|root,COG0612@2|Bacteria,2G5N3@200795|Chloroflexi,27XVK@189775|Thermomicrobia	189775|Thermomicrobia	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
CMS1_k127_3920877_7	383372.Rcas_3546	1.702e-77	273.0	COG0612@1|root,COG0612@2|Bacteria,2G68H@200795|Chloroflexi	200795|Chloroflexi	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
CMS1_k127_3937921_5	1382306.JNIM01000001_gene3957	1.653e-27	114.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
CMS1_k127_3937921_3	649747.HMPREF0083_02925	3.558e-71	248.0	COG1794@1|root,COG1794@2|Bacteria,1TR3U@1239|Firmicutes,4IQXA@91061|Bacilli	91061|Bacilli	M	Belongs to the aspartate glutamate racemases family	racX	-	5.1.1.13	ko:K01779	ko00250,ko01054,map00250,map01054	-	R00491	RC00302	ko00000,ko00001,ko01000	-	-	-	Asp_Glu_race
CMS1_k127_3937921_2	1128421.JAGA01000003_gene3247	1.442e-87	310.0	COG2304@1|root,COG2304@2|Bacteria,2NQHG@2323|unclassified Bacteria	2|Bacteria	S	Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
CMS1_k127_3937921_0	335541.Swol_1716	3.223e-166	559.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,1TQXZ@1239|Firmicutes,249E6@186801|Clostridia	186801|Clostridia	S	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	BatA,GATase1_like,VWA,VWA_2,VWA_3
CMS1_k127_3937921_1	357808.RoseRS_1741	4.524e-133	436.0	COG1473@1|root,COG1473@2|Bacteria,2G7D3@200795|Chloroflexi,375H2@32061|Chloroflexia	32061|Chloroflexia	S	peptidase dimerisation domain protein	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
CMS1_k127_3937921_4	1232410.KI421412_gene35	2.288e-45	168.0	COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,42NR8@68525|delta/epsilon subdivisions,2WM9T@28221|Deltaproteobacteria,43UPQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Peptidase dimerisation domain	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
CMS1_k127_39400_1	926550.CLDAP_19500	1.783e-53	202.0	COG0584@1|root,COG0823@1|root,COG3210@1|root,COG4886@1|root,COG0584@2|Bacteria,COG0823@2|Bacteria,COG3210@2|Bacteria,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	3.1.4.46	ko:K01126,ko:K21449	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000,ko02000	1.B.40.2	-	-	GDPD_2
CMS1_k127_39400_2	1385517.N800_10145	1.167e-45	192.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,1S0D5@1236|Gammaproteobacteria,1X4Y2@135614|Xanthomonadales	135614|Xanthomonadales	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_12
CMS1_k127_39400_0	251221.35214931	0.0	1047.0	COG1672@1|root,COG2319@1|root,COG1672@2|Bacteria,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria	2|Bacteria	A	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,NB-ARC,WD40
CMS1_k127_39400_4	216596.pRL120656	4.717e-07	55.0	2EN3K@1|root,33FRP@2|Bacteria,1NHFH@1224|Proteobacteria,2UVV3@28211|Alphaproteobacteria,4BGFH@82115|Rhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_39400_5	1267535.KB906767_gene1940	2.639e-05	50.0	COG1359@1|root,COG1359@2|Bacteria	2|Bacteria	S	Antibiotic biosynthesis monooxygenase	VY92_08690	-	5.3.1.32	ko:K11530	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000	-	-	-	ABM
CMS1_k127_39400_3	1041146.ATZB01000005_gene6245	5.461e-37	145.0	COG2514@1|root,COG2514@2|Bacteria	2|Bacteria	S	catechol 2,3-dioxygenase activity	-	-	1.13.11.2	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
CMS1_k127_3943657_5	926550.CLDAP_12470	1.626e-17	91.0	COG3815@1|root,COG3815@2|Bacteria,2G73B@200795|Chloroflexi	200795|Chloroflexi	O	Predicted membrane protein (DUF2085)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2085
CMS1_k127_3943657_4	926550.CLDAP_23600	1.572e-25	117.0	COG0167@1|root,COG0167@2|Bacteria	2|Bacteria	F	dihydroorotate dehydrogenase activity	-	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
CMS1_k127_3943657_3	1382306.JNIM01000001_gene4133	2.37e-27	122.0	COG0543@1|root,COG0543@2|Bacteria,2G75X@200795|Chloroflexi	200795|Chloroflexi	C	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
CMS1_k127_3943657_2	765420.OSCT_2243	7.774e-47	181.0	COG0697@1|root,COG0697@2|Bacteria,2G8KQ@200795|Chloroflexi,377W3@32061|Chloroflexia	32061|Chloroflexia	EG	EamA-like transporter family	-	-	-	ko:K03298	-	-	-	-	ko00000,ko02000	2.A.7.3	-	-	EamA
CMS1_k127_3943657_0	1121104.AQXH01000005_gene189	1.876e-182	589.0	COG0025@1|root,COG0025@2|Bacteria,4PKJ5@976|Bacteroidetes	976|Bacteroidetes	P	NhaP-type Na H and K H	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,TrkA_N
CMS1_k127_3943657_1	1121324.CLIT_4c00250	7.92e-133	445.0	COG0475@1|root,COG0569@1|root,COG0475@2|Bacteria,COG0569@2|Bacteria,1TS32@1239|Firmicutes,247XW@186801|Clostridia,25RVB@186804|Peptostreptococcaceae	186801|Clostridia	P	CPA2 family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
CMS1_k127_3948410_4	443254.Marpi_2115	4.887e-76	260.0	COG3635@1|root,COG3635@2|Bacteria,2GBZH@200918|Thermotogae	200918|Thermotogae	F	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	apgM	-	5.4.2.12	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,PhosphMutase
CMS1_k127_3948410_6	1453503.AU05_13500	2.863e-52	191.0	COG4339@1|root,COG4339@2|Bacteria,1MZ9X@1224|Proteobacteria,1S59I@1236|Gammaproteobacteria,1YGN1@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3948410_5	1194165.CAJF01000001_gene1978	4.528e-72	255.0	COG0673@1|root,COG0673@2|Bacteria,2GVBW@201174|Actinobacteria,4FTAH@85023|Microbacteriaceae	201174|Actinobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_3948410_3	272569.rrnAC0082	2.895e-84	296.0	arCOG14225@1|root,arCOG14225@2157|Archaea,2XYCA@28890|Euryarchaeota,23W9H@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3948410_8	1492737.FEM08_16310	2.643e-28	132.0	COG3387@1|root,COG3387@2|Bacteria,4NGFS@976|Bacteroidetes,1I0H9@117743|Flavobacteriia	976|Bacteroidetes	G	PFAM Glycoside hydrolase 15-related	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,Glyco_hydro_36
CMS1_k127_3948410_1	211165.AJLN01000100_gene4070	5.503e-186	598.0	COG1132@1|root,COG1132@2|Bacteria,1G1QS@1117|Cyanobacteria,1JK9K@1189|Stigonemataceae	1117|Cyanobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147,ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS1_k127_3948410_2	485913.Krac_3018	6.744e-170	554.0	COG1132@1|root,COG1132@2|Bacteria,2G86M@200795|Chloroflexi	2|Bacteria	P	COGs COG1132 ABC-type multidrug transport system ATPase and permease components	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS1_k127_3948410_10	1127134.NOCYR_3960	2.955e-26	112.0	COG0346@1|root,COG0346@2|Bacteria,2IQUP@201174|Actinobacteria,4G1DP@85025|Nocardiaceae	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
CMS1_k127_3948410_9	118173.KB235914_gene2716	2.992e-28	126.0	COG2334@1|root,COG2334@2|Bacteria,1G3HF@1117|Cyanobacteria,1H9GM@1150|Oscillatoriales	1117|Cyanobacteria	S	homoserine kinase type II (Protein kinase fold)	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS1_k127_3948410_12	1235457.C404_03565	1.079e-19	97.0	28WUQ@1|root,2ZIU4@2|Bacteria,1P7TM@1224|Proteobacteria,2W7CR@28216|Betaproteobacteria,1KEBR@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3948410_7	523791.Kkor_0184	6.221e-39	169.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	PA,PKD,Peptidase_S8
CMS1_k127_3948410_11	561175.KB894093_gene2988	1.784e-20	108.0	COG3291@1|root,COG3291@2|Bacteria,2GN7G@201174|Actinobacteria,4ER4V@85012|Streptosporangiales	201174|Actinobacteria	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	DUF5122,Malectin,PKD
CMS1_k127_3948410_0	1122182.KB903825_gene750	7.437e-216	713.0	COG1404@1|root,COG4935@1|root,COG1404@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	P_proprotein,Peptidase_S8,SLH,fn3
CMS1_k127_3951914_4	1445613.JALM01000067_gene5558	7.237e-80	276.0	COG3458@1|root,COG3458@2|Bacteria,2GNHH@201174|Actinobacteria,4E11A@85010|Pseudonocardiales	201174|Actinobacteria	Q	Acetyl xylan esterase (AXE1)	-	-	-	-	-	-	-	-	-	-	-	-	AXE1
CMS1_k127_3951914_3	1209989.TepiRe1_0697	9.87e-104	354.0	COG4091@1|root,COG4091@2|Bacteria,1TR51@1239|Firmicutes,24AUF@186801|Clostridia,42I69@68295|Thermoanaerobacterales	186801|Clostridia	E	SAF domain	-	-	-	-	-	-	-	-	-	-	-	-	DapB_N,F420_oxidored,NAD_binding_3,SAF
CMS1_k127_3951914_2	1082933.MEA186_35009	4.766e-104	351.0	COG4948@1|root,COG4948@2|Bacteria,1MURK@1224|Proteobacteria,2U0BF@28211|Alphaproteobacteria,43N9S@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	M	Mandelate racemase muconate	-	-	4.2.1.6	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R03033	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
CMS1_k127_3951914_0	1382306.JNIM01000001_gene2721	4.609e-137	442.0	COG0826@1|root,COG0826@2|Bacteria	2|Bacteria	O	peptidase U32	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_U32
CMS1_k127_3951914_1	247490.KSU1_C1116	3.228e-108	362.0	COG0436@1|root,COG0436@2|Bacteria,2IX5E@203682|Planctomycetes	203682|Planctomycetes	E	PFAM Aminotransferase class I and II	-	-	2.6.1.1	ko:K00812,ko:K10907	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS1_k127_3951914_6	877418.ATWV01000001_gene1730	1.957e-06	61.0	COG3210@1|root,COG3210@2|Bacteria,2J8YJ@203691|Spirochaetes	203691|Spirochaetes	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3951914_5	1254432.SCE1572_15400	4.971e-25	105.0	2BWQN@1|root,347D7@2|Bacteria,1P0PN@1224|Proteobacteria,431R8@68525|delta/epsilon subdivisions,2WW8A@28221|Deltaproteobacteria,2Z20I@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3956134_1	391037.Sare_0183	5.449e-53	195.0	COG1266@1|root,COG1266@2|Bacteria,2IGUR@201174|Actinobacteria,4DK0K@85008|Micromonosporales	201174|Actinobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
CMS1_k127_3956134_5	675635.Psed_0203	3.706e-07	56.0	2DNVA@1|root,32ZBE@2|Bacteria,2GRAT@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3956134_4	1385520.N802_17505	2.566e-12	67.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4FFUG@85021|Intrasporangiaceae	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS1_k127_3956134_3	1173027.Mic7113_0263	1.608e-12	74.0	COG0784@1|root,COG2198@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG5002@2|Bacteria,1GPYK@1117|Cyanobacteria,1HI8A@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF,HATPase_c,HisKA,Hpt,PAS_4,PHY,Response_reg
CMS1_k127_3956134_2	867845.KI911784_gene2559	1.898e-45	173.0	COG1999@1|root,COG1999@2|Bacteria,2G6UW@200795|Chloroflexi,375R3@32061|Chloroflexia	32061|Chloroflexia	S	Electron transport protein SCO1 SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
CMS1_k127_3956134_0	1121481.AUAS01000002_gene3527	1.217e-69	254.0	COG1524@1|root,COG1524@2|Bacteria,4PAJU@976|Bacteroidetes,47TWN@768503|Cytophagia	976|Bacteroidetes	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
CMS1_k127_3960158_20	765420.OSCT_0497	2.198e-15	79.0	2DPX2@1|root,333RW@2|Bacteria,2G7A0@200795|Chloroflexi,377B3@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function (DUF4013)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4013
CMS1_k127_3960158_21	1196029.ALIM01000014_gene2986	1.354e-14	82.0	COG0404@1|root,COG0404@2|Bacteria,1TRKX@1239|Firmicutes,4H9MX@91061|Bacilli,1ZAS5@1386|Bacillus	91061|Bacilli	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
CMS1_k127_3960158_1	675635.Psed_4920	9.984e-261	835.0	COG0404@1|root,COG0446@1|root,COG0404@2|Bacteria,COG0446@2|Bacteria,2GMBK@201174|Actinobacteria,4E081@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the GcvT family	-	-	1.5.3.1	ko:K00302	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	FAD_oxidored,Fer2_4,GCV_T,GCV_T_C,Pyr_redox_2
CMS1_k127_3960158_18	1144305.PMI02_01921	1.539e-19	92.0	COG4311@1|root,COG4311@2|Bacteria,1MZC3@1224|Proteobacteria,2UC8C@28211|Alphaproteobacteria,2K67W@204457|Sphingomonadales	204457|Sphingomonadales	E	Sarcosine oxidase delta subunit	-	-	1.5.3.1	ko:K00304	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	SoxD
CMS1_k127_3960158_2	1123023.JIAI01000007_gene1965	2.521e-195	617.0	COG0665@1|root,COG0665@2|Bacteria,2GNAE@201174|Actinobacteria,4EEMB@85010|Pseudonocardiales	201174|Actinobacteria	E	FAD dependent oxidoreductase	-	-	1.5.3.1	ko:K00303	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
CMS1_k127_3960158_4	1265505.ATUG01000002_gene1578	6.625e-135	446.0	COG5598@1|root,COG5598@2|Bacteria,1N18H@1224|Proteobacteria,42ME6@68525|delta/epsilon subdivisions,2WKDW@28221|Deltaproteobacteria,2MIBT@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Trimethylamine methyltransferase (MTTB)	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
CMS1_k127_3960158_9	926550.CLDAP_19760	2.186e-93	316.0	COG0646@1|root,COG0646@2|Bacteria,2G674@200795|Chloroflexi	200795|Chloroflexi	H	Homocysteine S-methyltransferase	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	S-methyl_trans
CMS1_k127_3960158_25	1051501.AYTL01000004_gene3867	8.761e-05	51.0	COG2318@1|root,COG2318@2|Bacteria,1V70V@1239|Firmicutes,4HJAI@91061|Bacilli,1ZIMU@1386|Bacillus	91061|Bacilli	S	DinB superfamily	yuaE	-	-	-	-	-	-	-	-	-	-	-	DinB_2
CMS1_k127_3960158_22	316274.Haur_3262	6.526e-11	71.0	COG3881@1|root,COG3881@2|Bacteria	2|Bacteria	S	PRC-barrel domain	yrrD	-	-	-	-	-	-	-	-	-	-	-	PRC
CMS1_k127_3960158_3	1265505.ATUG01000002_gene1456	7.585e-143	465.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,42P18@68525|delta/epsilon subdivisions,2WKTS@28221|Deltaproteobacteria,2MJEJ@213118|Desulfobacterales	28221|Deltaproteobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_3960158_7	1265505.ATUG01000002_gene1457	7.958e-102	340.0	COG1173@1|root,COG1173@2|Bacteria,1PEB6@1224|Proteobacteria,4305E@68525|delta/epsilon subdivisions,2WVA6@28221|Deltaproteobacteria,2MNHC@213118|Desulfobacterales	28221|Deltaproteobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
CMS1_k127_3960158_0	926550.CLDAP_32790	2.93e-287	897.0	COG0444@1|root,COG4608@1|root,COG0444@2|Bacteria,COG4608@2|Bacteria,2GBKB@200795|Chloroflexi	200795|Chloroflexi	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
CMS1_k127_3960158_16	309803.CTN_1430	9.543e-25	112.0	COG0517@1|root,COG0517@2|Bacteria	2|Bacteria	S	IMP dehydrogenase activity	-	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	CBS
CMS1_k127_3960158_6	489825.LYNGBM3L_71320	1.892e-103	342.0	COG4976@1|root,COG4976@2|Bacteria	2|Bacteria	O	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
CMS1_k127_3960158_12	1123242.JH636435_gene2898	8.215e-52	186.0	2DP8Y@1|root,3312C@2|Bacteria,2J1C0@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF4259)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4259
CMS1_k127_3960158_17	1123401.JHYQ01000014_gene848	8.06e-21	95.0	28MHU@1|root,2ZAUM@2|Bacteria,1R3RK@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3960158_14	1280390.CBQR020000061_gene1208	4.456e-38	146.0	2CRSQ@1|root,32SPK@2|Bacteria,1VXRI@1239|Firmicutes,4HXIC@91061|Bacilli,26YPJ@186822|Paenibacillaceae	91061|Bacilli	S	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
CMS1_k127_3960158_19	1033743.CAES01000047_gene605	1.341e-18	94.0	COG1846@1|root,COG1846@2|Bacteria,1V5VG@1239|Firmicutes,4HGXP@91061|Bacilli,26WVT@186822|Paenibacillaceae	91061|Bacilli	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	MarR
CMS1_k127_3960158_8	1449126.JQKL01000072_gene2880	4.749e-98	327.0	arCOG06802@1|root,2ZBBG@2|Bacteria,1V17K@1239|Firmicutes,24DHN@186801|Clostridia,26C9Q@186813|unclassified Clostridiales	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3960158_5	1033810.HLPCO_002507	3.922e-119	391.0	28IEB@1|root,2Z8GD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4037
CMS1_k127_3960158_10	1382306.JNIM01000001_gene2702	1.948e-85	289.0	COG0639@1|root,COG0639@2|Bacteria	2|Bacteria	T	phosphoprotein phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
CMS1_k127_3960158_24	679197.HMPREF9336_02347	1.102e-05	49.0	COG1073@1|root,COG1073@2|Bacteria,2GNB6@201174|Actinobacteria	201174|Actinobacteria	L	Alpha Beta	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
CMS1_k127_3960158_11	378806.STAUR_4199	1.561e-64	233.0	28M9U@1|root,2ZANN@2|Bacteria,1NXC3@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3960158_13	446470.Snas_2659	3.272e-38	168.0	COG4447@1|root,COG4447@2|Bacteria,2I4PF@201174|Actinobacteria	201174|Actinobacteria	E	Zinc metalloprotease (Elastase)	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CMS1_k127_3960158_15	314265.R2601_20441	1.706e-37	165.0	COG2706@1|root,COG2706@2|Bacteria,1QYRS@1224|Proteobacteria	1224|Proteobacteria	G	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3960158_23	926550.CLDAP_17850	1.038e-09	60.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	mshD	-	2.3.1.189	ko:K15520	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
CMS1_k127_3960778_1	1128421.JAGA01000002_gene1058	3.375e-133	433.0	COG0714@1|root,COG0714@2|Bacteria,2NNMQ@2323|unclassified Bacteria	2|Bacteria	S	ATPase associated with various cellular	moxR2	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS1_k127_3960778_4	765420.OSCT_2044	2.017e-46	182.0	2E0NP@1|root,32W7Q@2|Bacteria,2G9D8@200795|Chloroflexi,375QK@32061|Chloroflexia	32061|Chloroflexia	S	Domain of unknown function (DUF4350)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4350
CMS1_k127_3960778_5	1128421.JAGA01000002_gene1061	4.397e-39	160.0	2EQIM@1|root,33I4N@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4129)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
CMS1_k127_3960778_6	1128421.JAGA01000002_gene1062	3.717e-17	94.0	COG5180@1|root,COG5180@2|Bacteria,2NRZJ@2323|unclassified Bacteria	2|Bacteria	A	pathogenesis	CP_0034	-	-	ko:K02417,ko:K02519	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044,ko03012,ko03029	3.A.6.2,3.A.6.3	-	-	GPDPase_memb
CMS1_k127_3960778_0	926550.CLDAP_00120	1.093e-168	541.0	COG0124@1|root,COG0124@2|Bacteria,2G64E@200795|Chloroflexi	200795|Chloroflexi	J	PFAM tRNA synthetase class II (G H P and S)	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
CMS1_k127_3960778_2	926550.CLDAP_10170	3.421e-123	407.0	COG3356@1|root,COG3356@2|Bacteria,2G7ZP@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Neutral alkaline nonlysosomal ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3960778_3	926569.ANT_11070	1.167e-46	175.0	COG2971@1|root,COG2971@2|Bacteria,2G764@200795|Chloroflexi	200795|Chloroflexi	G	BadF/BadG/BcrA/BcrD ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
CMS1_k127_396670_1	926550.CLDAP_16520	4.307e-73	256.0	COG4948@1|root,COG4948@2|Bacteria,2G83T@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Mandelate racemase muconate lactonizing	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
CMS1_k127_396670_2	485913.Krac_10484	1.261e-52	192.0	COG4122@1|root,COG4122@2|Bacteria,2G8S5@200795|Chloroflexi	200795|Chloroflexi	S	PFAM O-methyltransferase, family 3	-	-	2.1.1.104	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	M00039,M00350	R01942,R06578	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_3
CMS1_k127_396670_0	485913.Krac_4116	2.671e-172	562.0	COG1506@1|root,COG1506@2|Bacteria,2G5NN@200795|Chloroflexi	2|Bacteria	E	Peptidase S9, prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
CMS1_k127_396670_3	13035.Dacsa_2208	0.0003847	46.0	COG5464@1|root,COG5464@2|Bacteria,1G21N@1117|Cyanobacteria	1117|Cyanobacteria	S	COGs COG5464 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF4351
CMS1_k127_3974023_11	525904.Tter_2002	1.035e-29	122.0	COG1577@1|root,COG1577@2|Bacteria,2NR5A@2323|unclassified Bacteria	2|Bacteria	I	GHMP kinases C terminal	mvk	-	1.1.1.88,2.3.3.10,2.7.1.36	ko:K00054,ko:K00869,ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,ko04146,map00072,map00280,map00650,map00900,map01100,map01110,map01130,map04146	M00088,M00095	R01978,R02081,R02245	RC00002,RC00004,RC00017,RC00503,RC00644	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
CMS1_k127_3974023_5	525904.Tter_2003	7.924e-80	273.0	COG1878@1|root,COG1878@2|Bacteria,2NRE5@2323|unclassified Bacteria	2|Bacteria	S	Putative cyclase	-	-	1.1.1.363,1.1.1.49,3.5.1.9	ko:K00036,ko:K07130	ko00030,ko00380,ko00480,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00380,map00480,map00630,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008,M00038	R00835,R00988,R01959,R02736,R04911,R10907	RC00001,RC00066,RC00263,RC00323	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cyclase
CMS1_k127_3974023_4	525904.Tter_2004	1.171e-91	305.0	COG0036@1|root,COG0036@2|Bacteria,2NP9N@2323|unclassified Bacteria	2|Bacteria	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575	5.1.3.1	ko:K01783,ko:K14587	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
CMS1_k127_3974023_7	1205683.CAKR01000026_gene3769	6.707e-76	269.0	COG1028@1|root,COG1028@2|Bacteria,1MWGC@1224|Proteobacteria,1RX7G@1236|Gammaproteobacteria,41GZK@629|Yersinia	1236|Gammaproteobacteria	IQ	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS1_k127_3974023_9	1120973.AQXL01000103_gene2504	4.639e-50	188.0	COG1414@1|root,COG1414@2|Bacteria,1TRMW@1239|Firmicutes,4HCSI@91061|Bacilli,278TK@186823|Alicyclobacillaceae	91061|Bacilli	K	helix_turn_helix isocitrate lyase regulation	kipR	-	-	ko:K13641	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR
CMS1_k127_3974023_2	391937.NA2_12733	6.324e-150	488.0	COG5476@1|root,COG5476@2|Bacteria,1MX4P@1224|Proteobacteria,2TS1C@28211|Alphaproteobacteria,43J6P@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1485,MlrC_C
CMS1_k127_3974023_8	479434.Sthe_0680	1.311e-51	203.0	COG0747@1|root,COG0747@2|Bacteria,2GAP8@200795|Chloroflexi,27YXK@189775|Thermomicrobia	189775|Thermomicrobia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_3974023_3	604331.AUHY01000041_gene506	1.157e-93	318.0	COG0601@1|root,COG0601@2|Bacteria,1WMC0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_3974023_6	292459.STH2654	1.428e-78	273.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia	186801|Clostridia	P	ABC-type dipeptide oligopeptide nickel transport	oppC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
CMS1_k127_3974023_1	1380394.JADL01000004_gene5716	4.997e-181	576.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,2TT6G@28211|Alphaproteobacteria,2JRU8@204441|Rhodospirillales	204441|Rhodospirillales	H	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
CMS1_k127_3974023_0	309801.trd_0495	7.324e-241	755.0	COG2225@1|root,COG2225@2|Bacteria,2G63R@200795|Chloroflexi,27Y0V@189775|Thermomicrobia	189775|Thermomicrobia	C	Malate synthase	-	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
CMS1_k127_3974023_10	1382306.JNIM01000001_gene227	1.959e-34	138.0	COG1618@1|root,COG1618@2|Bacteria	2|Bacteria	F	nucleotide phosphatase activity, acting on free nucleotides	mobA	-	2.7.4.9,2.7.7.77,3.6.1.15,3.6.1.55,3.6.3.29,3.6.3.34	ko:K00943,ko:K02013,ko:K02017,ko:K03574,ko:K03752,ko:K06928	ko00230,ko00240,ko00730,ko00790,ko01100,ko02010,map00230,map00240,map00730,map00790,map01100,map02010	M00053,M00189,M00240	R00086,R00615,R02094,R02098,R11581	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000,ko03400	3.A.1.14,3.A.1.8	-	-	DUF2478,NTPase_1
CMS1_k127_3975493_0	316274.Haur_2849	0.0	1051.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,2G88G@200795|Chloroflexi,37686@32061|Chloroflexia	2|Bacteria	O	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Laminin_G_3,Metallophos,Metallophos_C,PA,PKD,Peptidase_S8,Reprolysin_4
CMS1_k127_3975493_1	589865.DaAHT2_1709	1.503e-157	510.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,42N91@68525|delta/epsilon subdivisions,2WIMM@28221|Deltaproteobacteria,2MIKE@213118|Desulfobacterales	28221|Deltaproteobacteria	J	RNA-metabolising metallo-beta-lactamase	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
CMS1_k127_3981858_2	926569.ANT_30000	3.664e-214	690.0	COG1193@1|root,COG1193@2|Bacteria,2G5R8@200795|Chloroflexi	200795|Chloroflexi	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_III,MutS_V,Smr
CMS1_k127_3981858_0	1128421.JAGA01000003_gene3718	1.305e-221	704.0	COG1132@1|root,COG1132@2|Bacteria,2NNVD@2323|unclassified Bacteria	2|Bacteria	V	ABC transporter	msbA	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS1_k127_3981858_8	1034347.CAHJ01000025_gene3486	4.717e-15	78.0	COG0388@1|root,COG0388@2|Bacteria,1TQR9@1239|Firmicutes,4HDUI@91061|Bacilli,1ZBD0@1386|Bacillus	91061|Bacilli	S	Carbon-nitrogen hydrolase	-	-	3.5.5.1	ko:K01501	ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120	-	R00540,R01887,R03093,R03542,R05591,R07855	RC00315,RC00325,RC00617,RC00959,RC02811	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
CMS1_k127_3981858_9	517418.Ctha_1726	9.902e-09	64.0	COG0457@1|root,COG2199@1|root,COG0457@2|Bacteria,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HAMP,TPR_12,TPR_7,TPR_8
CMS1_k127_3981858_5	1128421.JAGA01000003_gene3678	2.889e-34	141.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2NQCZ@2323|unclassified Bacteria	2|Bacteria	K	NB-ARC domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_22,BTAD,NB-ARC,TPR_10,TPR_12,TPR_8,Trans_reg_C
CMS1_k127_3981858_4	485913.Krac_2635	1.133e-35	139.0	COG0457@1|root,COG3629@1|root,COG3899@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG3899@2|Bacteria,2G871@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,TPR_12
CMS1_k127_3981858_7	864051.BurJ1DRAFT_2762	2.65e-16	83.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2VH80@28216|Betaproteobacteria,1KN43@119065|unclassified Burkholderiales	28216|Betaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
CMS1_k127_3981858_6	526227.Mesil_3475	1.146e-33	133.0	COG4274@1|root,COG4274@2|Bacteria	2|Bacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
CMS1_k127_3981858_1	1038860.AXAP01000104_gene4208	1.621e-221	699.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,3JTDD@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	MA20_18835	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
CMS1_k127_3981858_10	1123242.JH636435_gene1056	1.01e-07	54.0	COG0388@1|root,COG0388@2|Bacteria,2IX51@203682|Planctomycetes	203682|Planctomycetes	S	Carbon-nitrogen hydrolase	-	-	3.5.5.1	ko:K01501	ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120	-	R00540,R01887,R03093,R03542,R05591,R07855	RC00315,RC00325,RC00617,RC00959,RC02811	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
CMS1_k127_3981858_3	1382304.JNIL01000001_gene492	6.625e-40	150.0	COG0388@1|root,COG0388@2|Bacteria,1TQR9@1239|Firmicutes,4HDUI@91061|Bacilli,27A9E@186823|Alicyclobacillaceae	91061|Bacilli	S	Carbon-nitrogen hydrolase	-	-	3.5.5.1	ko:K01501	ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120	-	R00540,R01887,R03093,R03542,R05591,R07855	RC00315,RC00325,RC00617,RC00959,RC02811	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
CMS1_k127_3996444_1	1440053.JOEI01000002_gene3549	6.018e-27	115.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria	201174|Actinobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS1_k127_3996444_2	1303518.CCALI_00530	1.301e-20	96.0	2EFWM@1|root,339NX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3996444_0	386456.JQKN01000005_gene441	3.447e-54	201.0	arCOG10178@1|root,arCOG10178@2157|Archaea,2XY0I@28890|Euryarchaeota	28890|Euryarchaeota	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
CMS1_k127_4001108_0	243274.THEMA_03180	1.049e-146	488.0	COG0747@1|root,COG0747@2|Bacteria,2GCNZ@200918|Thermotogae	200918|Thermotogae	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_4001108_1	1499967.BAYZ01000056_gene4887	2.761e-86	295.0	COG2421@1|root,COG2421@2|Bacteria,2NR72@2323|unclassified Bacteria	2|Bacteria	C	Acetamidase/Formamidase family	-	-	-	-	-	-	-	-	-	-	-	-	FmdA_AmdA
CMS1_k127_4001108_2	1380394.JADL01000017_gene482	7.079e-68	239.0	COG1921@1|root,COG1921@2|Bacteria,1MWCB@1224|Proteobacteria,2TXI4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	L-seryl-tRNA selenium transferase	-	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	SelA
CMS1_k127_4018865_2	1122919.KB905558_gene1251	3.362e-18	89.0	COG0673@1|root,COG0673@2|Bacteria,1TQ72@1239|Firmicutes,4HAGN@91061|Bacilli,26ST6@186822|Paenibacillaceae	91061|Bacilli	K	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_4018865_1	251229.Chro_4812	3.574e-53	209.0	COG2372@1|root,COG2372@2|Bacteria	2|Bacteria	C	response to copper ion	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF4082,SASA,SLH
CMS1_k127_4018865_0	525904.Tter_2216	1.146e-96	325.0	COG0395@1|root,COG0395@2|Bacteria,2NPII@2323|unclassified Bacteria	2|Bacteria	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02026,ko:K05815	ko02010,map02010	M00198,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.3	-	-	BPD_transp_1
CMS1_k127_4019825_3	909663.KI867150_gene1749	2.27e-58	211.0	COG0463@1|root,COG0463@2|Bacteria,1QW3P@1224|Proteobacteria,42QT7@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	glycosyl transferase family 2	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	DUF2304,Glycos_transf_2
CMS1_k127_4019825_6	1122917.KB899664_gene3089	1.414e-08	63.0	COG2456@1|root,COG2456@2|Bacteria,1UPVP@1239|Firmicutes,4HNQC@91061|Bacilli,26YN9@186822|Paenibacillaceae	91061|Bacilli	S	Uncharacterized conserved protein (DUF2304)	-	-	-	ko:K09153	-	-	-	-	ko00000	-	-	-	DUF2304
CMS1_k127_4019825_0	373903.Hore_17270	3.465e-116	398.0	COG3379@1|root,COG3379@2|Bacteria,1VHYF@1239|Firmicutes,24VS8@186801|Clostridia	186801|Clostridia	Q	type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
CMS1_k127_4019825_1	1499967.BAYZ01000028_gene1230	1.537e-63	229.0	COG0726@1|root,COG0726@2|Bacteria,2NPFG@2323|unclassified Bacteria	2|Bacteria	G	Domain of unknown function (DUF3473)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3473,Polysacc_deac_1
CMS1_k127_4019825_4	1095769.CAHF01000010_gene1326	1.842e-28	128.0	COG2348@1|root,COG2348@2|Bacteria,1MXFY@1224|Proteobacteria,2VNEW@28216|Betaproteobacteria,475EC@75682|Oxalobacteraceae	28216|Betaproteobacteria	V	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
CMS1_k127_4019825_5	1123392.AQWL01000002_gene1947	1.941e-26	129.0	COG0457@1|root,COG5010@1|root,COG0457@2|Bacteria,COG5010@2|Bacteria,1MXMD@1224|Proteobacteria,2VIMP@28216|Betaproteobacteria	28216|Betaproteobacteria	O	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_8
CMS1_k127_4019825_2	290317.Cpha266_0087	1.517e-61	228.0	COG0477@1|root,COG2814@2|Bacteria,1FDXJ@1090|Chlorobi	1090|Chlorobi	EGP	major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
CMS1_k127_4019825_7	316067.Geob_2974	2.929e-08	58.0	COG0399@1|root,COG0399@2|Bacteria,1PDU2@1224|Proteobacteria,42RZB@68525|delta/epsilon subdivisions,2WNIE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
CMS1_k127_40262_3	869210.Marky_1283	3.927e-90	306.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1WIA7@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	PFAM Conserved region in glutamate synthase	-	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
CMS1_k127_40262_7	324602.Caur_2697	2.744e-58	206.0	COG1403@1|root,COG1403@2|Bacteria,2G6WV@200795|Chloroflexi,375TQ@32061|Chloroflexia	32061|Chloroflexia	L	SMART HNH nuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
CMS1_k127_40262_4	1382306.JNIM01000001_gene527	5.618e-84	285.0	COG1051@1|root,COG1051@2|Bacteria,2G6QH@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the Nudix hydrolase family	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
CMS1_k127_40262_5	926569.ANT_13590	1.075e-78	271.0	COG1335@1|root,COG1335@2|Bacteria,2G6JY@200795|Chloroflexi	200795|Chloroflexi	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
CMS1_k127_40262_8	326427.Cagg_3625	2.758e-48	175.0	COG2018@1|root,COG2018@2|Bacteria,2G8WW@200795|Chloroflexi,375M5@32061|Chloroflexia	32061|Chloroflexia	S	PFAM Roadblock LC7 family protein	-	-	-	ko:K07131	-	-	-	-	ko00000	-	-	-	Robl_LC7
CMS1_k127_40262_1	926550.CLDAP_31490	1.561e-174	566.0	COG1032@1|root,COG1032@2|Bacteria,2G7YA@200795|Chloroflexi	200795|Chloroflexi	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
CMS1_k127_40262_2	937777.Deipe_0860	4.469e-93	321.0	COG2271@1|root,COG2271@2|Bacteria	2|Bacteria	G	transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_40262_6	1444309.JAQG01000031_gene2895	3.781e-59	209.0	COG1051@1|root,COG1051@2|Bacteria,1V6D5@1239|Firmicutes,4HJTU@91061|Bacilli,26XD5@186822|Paenibacillaceae	91061|Bacilli	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS1_k127_40262_9	686340.Metal_3032	9.578e-08	55.0	COG4691@1|root,COG4691@2|Bacteria,1N09T@1224|Proteobacteria,1SH18@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Plasmid stability protein	-	-	-	ko:K21495	-	-	-	-	ko00000,ko02048	-	-	-	Arc
CMS1_k127_40262_0	573413.Spirs_3975	5.483e-199	627.0	COG0209@1|root,COG0209@2|Bacteria,2J5M3@203691|Spirochaetes	203691|Spirochaetes	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC,Ribonuc_red_lgN
CMS1_k127_4027592_2	1232449.BAHV02000010_gene2498	3.56e-48	182.0	COG0500@1|root,COG2226@2|Bacteria,1TSAZ@1239|Firmicutes,2496P@186801|Clostridia,26A45@186813|unclassified Clostridiales	186801|Clostridia	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS1_k127_4027592_0	479434.Sthe_2033	1.704e-123	408.0	COG0477@1|root,COG0477@2|Bacteria,2G5UF@200795|Chloroflexi	200795|Chloroflexi	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_4027592_1	313624.NSP_2760	3.7e-86	296.0	COG1132@1|root,COG1132@2|Bacteria,1G1QS@1117|Cyanobacteria,1HS1R@1161|Nostocales	1117|Cyanobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147,ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS1_k127_4035387_11	192952.MM_0224	1.186e-07	53.0	COG3585@1|root,arCOG00228@2157|Archaea,2Y699@28890|Euryarchaeota,2NBCT@224756|Methanomicrobia	224756|Methanomicrobia	H	TOBE domain	-	-	-	-	-	-	-	-	-	-	-	-	TOBE
CMS1_k127_4035387_6	316274.Haur_1961	5.558e-89	304.0	COG3173@1|root,COG3173@2|Bacteria,2G8QR@200795|Chloroflexi	200795|Chloroflexi	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS1_k127_4035387_5	344747.PM8797T_05050	1.69e-91	307.0	COG3836@1|root,COG3836@2|Bacteria,2IX9H@203682|Planctomycetes	2|Bacteria	G	Belongs to the HpcH HpaI aldolase family	MA20_09190	-	2.7.7.38,4.1.2.20,4.1.2.52	ko:K00979,ko:K01630,ko:K02510	ko00053,ko00350,ko00540,ko01100,ko01120,map00053,map00350,map00540,map01100,map01120	M00063	R01645,R01647,R02754,R03277,R03351,R11396	RC00152,RC00307,RC00435,RC00572,RC00574,RC00910,RC03057	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	HpcH_HpaI
CMS1_k127_4035387_8	1382358.JHVN01000003_gene2716	4.123e-61	220.0	COG0454@1|root,COG0454@2|Bacteria,1UJQZ@1239|Firmicutes,4ITDK@91061|Bacilli	91061|Bacilli	K	-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
CMS1_k127_4035387_9	1540221.JQNI01000002_gene1131	9.216e-58	207.0	COG1305@1|root,COG1305@2|Bacteria	2|Bacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
CMS1_k127_4035387_2	1126627.BAWE01000005_gene5292	6.658e-195	612.0	COG1063@1|root,COG1063@2|Bacteria,1MV9A@1224|Proteobacteria,2TSWA@28211|Alphaproteobacteria,3JRCS@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Glucose dehydrogenase C-terminus	MA20_31690	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_4035387_10	1387312.BAUS01000007_gene2486	1.097e-10	70.0	COG4106@1|root,COG4106@2|Bacteria,1R14J@1224|Proteobacteria	1224|Proteobacteria	S	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS1_k127_4035387_4	1195236.CTER_3697	6.639e-105	348.0	COG0451@1|root,COG0451@2|Bacteria,1TQY1@1239|Firmicutes,24DZ6@186801|Clostridia	186801|Clostridia	GM	NAD dependent epimerase dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
CMS1_k127_4035387_0	479434.Sthe_3483	6.549e-266	827.0	COG3653@1|root,COG3653@2|Bacteria,2G5ZI@200795|Chloroflexi,27XTY@189775|Thermomicrobia	189775|Thermomicrobia	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
CMS1_k127_4035387_1	402881.Plav_2593	8.285e-214	689.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TQMV@28211|Alphaproteobacteria,1JPPK@119043|Rhodobiaceae	28211|Alphaproteobacteria	G	PQQ enzyme repeat	-	-	1.1.5.2	ko:K00117	ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130	-	R06620	RC00066	ko00000,ko00001,ko01000	-	-	-	PQQ,PQQ_2
CMS1_k127_4035387_7	926550.CLDAP_38940	1.662e-81	280.0	COG3375@1|root,COG3375@2|Bacteria,2G8MH@200795|Chloroflexi	200795|Chloroflexi	M	carboxylic acid catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4035387_3	1207063.P24_07374	1.734e-164	528.0	COG5476@1|root,COG5476@2|Bacteria,1MX4P@1224|Proteobacteria,2TS1C@28211|Alphaproteobacteria,2JW54@204441|Rhodospirillales	204441|Rhodospirillales	S	MlrC C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	DUF1485,MlrC_C
CMS1_k127_4039461_1	869210.Marky_1055	9.013e-189	596.0	COG0183@1|root,COG0183@2|Bacteria,1WID7@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
CMS1_k127_4039461_3	926550.CLDAP_21180	1.204e-45	167.0	COG0640@1|root,COG0640@2|Bacteria,2G6YR@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
CMS1_k127_4039461_0	926550.CLDAP_21170	6.981e-310	965.0	COG2217@1|root,COG2217@2|Bacteria,2G65K@200795|Chloroflexi	200795|Chloroflexi	P	Heavy-metal-associated domain	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
CMS1_k127_4039461_2	357808.RoseRS_2494	4.842e-107	361.0	COG0517@1|root,COG1993@1|root,COG0517@2|Bacteria,COG1993@2|Bacteria,2G69Z@200795|Chloroflexi,376P4@32061|Chloroflexia	32061|Chloroflexia	T	PFAM CBS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS,DUF190
CMS1_k127_4039461_4	401526.TcarDRAFT_0153	6.622e-32	128.0	COG0239@1|root,COG0239@2|Bacteria,1VEH7@1239|Firmicutes,4H4YH@909932|Negativicutes	909932|Negativicutes	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
CMS1_k127_4052500_3	316274.Haur_1055	1.656e-45	173.0	COG0609@1|root,COG0609@2|Bacteria,2G6E8@200795|Chloroflexi,376D1@32061|Chloroflexia	32061|Chloroflexia	P	FecCD transport family	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
CMS1_k127_4052500_2	316274.Haur_1056	3.418e-86	299.0	COG0614@1|root,COG0614@2|Bacteria,2G6TS@200795|Chloroflexi,3763Q@32061|Chloroflexia	32061|Chloroflexia	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
CMS1_k127_4052500_0	926550.CLDAP_23850	7.345e-159	516.0	COG0079@1|root,COG1492@1|root,COG0079@2|Bacteria,COG1492@2|Bacteria,2G5PU@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,CbiA,GATase_3
CMS1_k127_4052500_1	765420.OSCT_2415	5.643e-113	372.0	COG2038@1|root,COG2038@2|Bacteria,2G5R3@200795|Chloroflexi,376BT@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)	cobT	-	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	-	DBI_PRT
CMS1_k127_4061504_2	1353531.AZNX01000014_gene3221	3.931e-120	400.0	COG2159@1|root,COG2159@2|Bacteria,1ND2I@1224|Proteobacteria,2UIP1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CMS1_k127_4061504_0	926550.CLDAP_10210	9.466e-153	497.0	COG0527@1|root,COG0527@2|Bacteria,2G5U9@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the aspartokinase family	metL	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
CMS1_k127_4061504_6	300852.55772218	7.719e-17	88.0	COG0607@1|root,COG0607@2|Bacteria,1WJ03@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CMS1_k127_4061504_3	485913.Krac_10951	3.365e-117	386.0	COG0476@1|root,COG0476@2|Bacteria,2G5Q1@200795|Chloroflexi	200795|Chloroflexi	H	ThiF family	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
CMS1_k127_4061504_5	123214.PERMA_1023	2.46e-22	102.0	COG1310@1|root,COG1310@2|Bacteria,2G540@200783|Aquificae	200783|Aquificae	S	Mov34 MPN PAD-1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Prok-JAB
CMS1_k127_4061504_1	926550.CLDAP_15990	2.172e-139	454.0	COG0626@1|root,COG0626@2|Bacteria	2|Bacteria	E	cystathionine gamma-synthase activity	metB	-	2.5.1.48,4.4.1.11,4.4.1.8	ko:K01739,ko:K01760,ko:K01761	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00654,R00782,R00999,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04941,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00196,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
CMS1_k127_4061504_7	357808.RoseRS_1208	1.269e-05	52.0	28I2M@1|root,2Z85A@2|Bacteria,2GBPD@200795|Chloroflexi,376A1@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function (DUF4058)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4058
CMS1_k127_4061504_4	1121403.AUCV01000065_gene4170	1.443e-93	326.0	COG0025@1|root,COG0025@2|Bacteria,1MW5T@1224|Proteobacteria,42M9Y@68525|delta/epsilon subdivisions,2X5IZ@28221|Deltaproteobacteria,2MPF3@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger
CMS1_k127_4074236_2	880073.Calab_3471	6.17e-06	59.0	COG1672@1|root,COG3710@1|root,COG1672@2|Bacteria,COG3710@2|Bacteria,2NR41@2323|unclassified Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	AAA_16,DUF234,LRR_4,Trans_reg_C,WG_beta_rep
CMS1_k127_4074236_1	926569.ANT_28690	1.051e-25	124.0	COG3868@1|root,COG3868@2|Bacteria,2G983@200795|Chloroflexi	200795|Chloroflexi	S	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
CMS1_k127_4074236_0	526225.Gobs_1155	8.08e-46	187.0	COG4995@1|root,COG4995@2|Bacteria,2IJMG@201174|Actinobacteria,4EW9G@85013|Frankiales	201174|Actinobacteria	S	SIR2-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,SIR2_2
CMS1_k127_4083070_12	665956.HMPREF1032_02902	1.002e-25	108.0	COG0110@1|root,COG2827@1|root,COG0110@2|Bacteria,COG2827@2|Bacteria,1VEZF@1239|Firmicutes,24QYU@186801|Clostridia,3WKVK@541000|Ruminococcaceae	186801|Clostridia	L	GIY-YIG catalytic domain protein	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
CMS1_k127_4083070_9	926569.ANT_30860	1.256e-40	158.0	COG0204@1|root,COG0204@2|Bacteria,2G78P@200795|Chloroflexi	200795|Chloroflexi	I	PFAM phospholipid glycerol acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
CMS1_k127_4083070_6	926550.CLDAP_03010	7.986e-53	198.0	COG1388@1|root,COG1388@2|Bacteria,2G9RQ@200795|Chloroflexi	200795|Chloroflexi	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
CMS1_k127_4083070_5	926550.CLDAP_01660	2.063e-86	294.0	COG4974@1|root,COG4974@2|Bacteria,2G6CI@200795|Chloroflexi	200795|Chloroflexi	L	Belongs to the 'phage' integrase family	xerC	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
CMS1_k127_4083070_10	926550.CLDAP_01480	1.169e-33	131.0	COG0184@1|root,COG0184@2|Bacteria,2G791@200795|Chloroflexi	200795|Chloroflexi	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
CMS1_k127_4083070_0	926569.ANT_10570	1.102e-265	837.0	COG1185@1|root,COG1185@2|Bacteria,2G5TS@200795|Chloroflexi	200795|Chloroflexi	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
CMS1_k127_4083070_7	926550.CLDAP_07070	1.526e-50	186.0	COG0681@1|root,COG0681@2|Bacteria	2|Bacteria	U	signal peptide processing	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
CMS1_k127_4083070_1	926569.ANT_11040	1.033e-164	536.0	COG0441@1|root,COG0572@1|root,COG0441@2|Bacteria,COG0572@2|Bacteria,2G9NH@200795|Chloroflexi	200795|Chloroflexi	F	Phosphoribulokinase / Uridine kinase family	-	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
CMS1_k127_4083070_2	926561.KB900618_gene142	2.984e-100	337.0	COG1363@1|root,COG1363@2|Bacteria,1TNZT@1239|Firmicutes,248D0@186801|Clostridia	186801|Clostridia	G	M42 glutamyl aminopeptidase	celM	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Peptidase_M42
CMS1_k127_4083070_4	644966.Tmar_1691	1.768e-90	309.0	COG1363@1|root,COG1363@2|Bacteria,1TNZT@1239|Firmicutes,248D0@186801|Clostridia	186801|Clostridia	G	M42 glutamyl aminopeptidase	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Peptidase_M42
CMS1_k127_4083070_3	2325.TKV_c04220	1.28e-96	327.0	COG1363@1|root,COG1363@2|Bacteria,1TNZT@1239|Firmicutes,24BAN@186801|Clostridia,42F2W@68295|Thermoanaerobacterales	186801|Clostridia	C	peptidase M42 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
CMS1_k127_4083070_8	1333523.L593_12400	1.22e-44	167.0	COG3358@1|root,arCOG04570@2157|Archaea,2XX3J@28890|Euryarchaeota,23VM5@183963|Halobacteria	183963|Halobacteria	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
CMS1_k127_4083070_11	515635.Dtur_1616	3.875e-32	135.0	COG0561@1|root,COG0561@2|Bacteria	2|Bacteria	Q	phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
CMS1_k127_4093784_1	1128421.JAGA01000002_gene1765	2.35e-70	245.0	COG2197@1|root,COG2197@2|Bacteria,2NPMZ@2323|unclassified Bacteria	2|Bacteria	T	helix_turn_helix, Lux Regulon	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	GerE,Response_reg
CMS1_k127_4093784_2	1382306.JNIM01000001_gene1046	1.443e-65	237.0	COG4585@1|root,COG4585@2|Bacteria,2G6F0@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA_3,sCache_3_2
CMS1_k127_4093784_0	134676.ACPL_4277	4.322e-100	340.0	COG0053@1|root,COG0053@2|Bacteria,2GJ8Q@201174|Actinobacteria,4DAXX@85008|Micromonosporales	201174|Actinobacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
CMS1_k127_4093784_4	485913.Krac_4458	2.073e-27	116.0	COG0640@1|root,COG0640@2|Bacteria,2G78R@200795|Chloroflexi	485913.Krac_4458|-	K	PFAM regulatory protein, ArsR	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4093784_3	383372.Rcas_2710	6.879e-52	186.0	COG0664@1|root,COG1136@1|root,COG0664@2|Bacteria,COG1136@2|Bacteria,2G6C9@200795|Chloroflexi,37685@32061|Chloroflexia	32061|Chloroflexia	V	ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,cNMP_binding
CMS1_k127_4094722_4	521045.Kole_0693	5.211e-23	107.0	COG1653@1|root,COG1653@2|Bacteria,2GCPM@200918|Thermotogae	200918|Thermotogae	G	Extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1
CMS1_k127_4094722_2	309807.SRU_1615	4.559e-35	136.0	COG0296@1|root,COG0296@2|Bacteria	2|Bacteria	G	1,4-alpha-glucan branching enzyme activity	-	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	AMPK1_CBM,Alpha-amylase,Alpha-amylase_C,CBM_48
CMS1_k127_4094722_0	63737.Npun_F1795	0.0	1116.0	COG3387@1|root,COG3387@2|Bacteria,1G3RH@1117|Cyanobacteria,1HR83@1161|Nostocales	1117|Cyanobacteria	G	Glucodextranase, domain N	-	-	3.2.1.3	ko:K01178	ko00500,ko01100,map00500,map01100	-	R01790,R01791,R06199	-	ko00000,ko00001,ko01000	-	GH15	-	Glucodextran_N,Glyco_hydro_15
CMS1_k127_4094722_1	240302.BN982_03964	3.997e-98	328.0	COG1230@1|root,COG1230@2|Bacteria,1TR92@1239|Firmicutes,4HBCQ@91061|Bacilli,3NEHQ@45667|Halobacillus	91061|Bacilli	P	Cation efflux family	czcD	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
CMS1_k127_4094722_3	649638.Trad_1692	3.005e-30	120.0	COG1917@1|root,COG1917@2|Bacteria,1WMW1@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS1_k127_4094722_6	551115.Aazo_4773	1.825e-15	77.0	COG1917@1|root,COG1917@2|Bacteria,1G6N4@1117|Cyanobacteria,1HNHN@1161|Nostocales	1117|Cyanobacteria	S	PFAM Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS1_k127_4094722_5	323848.Nmul_A1287	9.566e-21	95.0	COG0642@1|root,COG2199@1|root,COG2202@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,1NRP8@1224|Proteobacteria,2VJNX@28216|Betaproteobacteria,3729X@32003|Nitrosomonadales	28216|Betaproteobacteria	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
CMS1_k127_4111283_0	552811.Dehly_1516	3.856e-188	620.0	COG2909@1|root,COG2909@2|Bacteria,2G7Q4@200795|Chloroflexi	200795|Chloroflexi	K	ATP-dependent transcriptional regulator, MalT-like, LuxR family	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
CMS1_k127_4111283_1	1007103.AFHW01000028_gene1695	8.749e-97	335.0	COG1680@1|root,COG1680@2|Bacteria,1UZZ5@1239|Firmicutes,4HA1I@91061|Bacilli,274N2@186822|Paenibacillaceae	91061|Bacilli	V	Beta-lactamase	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase
CMS1_k127_4111376_0	2002.JOEQ01000003_gene2490	1.825e-144	463.0	COG0031@1|root,COG0031@2|Bacteria,2GIXE@201174|Actinobacteria,4EI60@85012|Streptosporangiales	201174|Actinobacteria	EK	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS1_k127_4111376_3	413404.Rmag_1064	5.465e-07	61.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,1RMAU@1236|Gammaproteobacteria,1J4ZD@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008425,GO:0008757,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016741,GO:0030580,GO:0032259,GO:0042180,GO:0042181,GO:0043333,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b3833,iBWG_1329.BWG_3511,iE2348C_1286.E2348C_4147,iEC042_1314.EC042_4213,iEC55989_1330.EC55989_4310,iECDH10B_1368.ECDH10B_4024,iECDH1ME8569_1439.ECDH1ME8569_3712,iECH74115_1262.ECH74115_5274,iECIAI1_1343.ECIAI1_4028,iECIAI39_1322.ECIAI39_3162,iECO103_1326.ECO103_4330,iECO111_1330.ECO111_4661,iECO26_1355.ECO26_4752,iECSE_1348.ECSE_4121,iECSP_1301.ECSP_4888,iECUMN_1333.ECUMN_4359,iECW_1372.ECW_m4135,iECs_1301.ECs4763,iEKO11_1354.EKO11_4524,iETEC_1333.ETEC_4110,iEcDH1_1363.EcDH1_4146,iEcE24377_1341.EcE24377A_4354,iEcHS_1320.EcHS_A4057,iEcSMS35_1347.EcSMS35_4216,iEcolC_1368.EcolC_4175,iG2583_1286.G2583_4633,iJO1366.b3833,iJR904.b3833,iSBO_1134.SBO_3847,iSDY_1059.SDY_3910,iSFV_1184.SFV_3665,iSF_1195.SF3911,iSFxv_1172.SFxv_4263,iSSON_1240.SSON_4008,iS_1188.S3843,iSbBS512_1146.SbBS512_E4305,iUMNK88_1353.UMNK88_4663,iWFL_1372.ECW_m4135,iY75_1357.Y75_RS17910,iZ_1308.Z5355	Ubie_methyltran
CMS1_k127_4111376_2	335659.S23_68830	3.029e-27	124.0	COG3173@1|root,COG3173@2|Bacteria,1R7XK@1224|Proteobacteria,2TTWB@28211|Alphaproteobacteria,3JSZR@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Ecdysteroid kinase	-	-	-	-	-	-	-	-	-	-	-	-	APH,EcKinase
CMS1_k127_4111376_1	485913.Krac_4803	7.482e-68	240.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
CMS1_k127_4112677_5	1168289.AJKI01000004_gene2942	1.834e-05	56.0	COG0457@1|root,COG2972@1|root,COG0457@2|Bacteria,COG2972@2|Bacteria,4NF45@976|Bacteroidetes,2G0ER@200643|Bacteroidia,3XIJ8@558415|Marinilabiliaceae	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase,TPR_12
CMS1_k127_4112677_2	293826.Amet_4544	8.501e-94	325.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,248TY@186801|Clostridia,36EWX@31979|Clostridiaceae	186801|Clostridia	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
CMS1_k127_4112677_0	316274.Haur_3718	3.261e-167	537.0	COG0031@1|root,COG0517@1|root,COG0031@2|Bacteria,COG0517@2|Bacteria,2G5PG@200795|Chloroflexi,3751N@32061|Chloroflexia	2|Bacteria	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47,4.2.1.22	ko:K01697,ko:K01738,ko:K18926	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00035,M00338,M00715	R00891,R00897,R01290,R03601,R04859,R04942	RC00020,RC00056,RC00069,RC00256,RC00489,RC01246,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000,ko02000	2.A.1.3.30	-	-	CBS,MFS_1,PALP
CMS1_k127_4112677_3	383372.Rcas_2993	2.064e-90	310.0	COG0116@1|root,COG0116@2|Bacteria,2GBRV@200795|Chloroflexi,376UC@32061|Chloroflexia	32061|Chloroflexia	L	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	UPF0020
CMS1_k127_4112677_4	479434.Sthe_3307	2.001e-52	196.0	COG0500@1|root,COG2226@2|Bacteria,2G8RQ@200795|Chloroflexi	200795|Chloroflexi	H	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS1_k127_4112677_1	926550.CLDAP_05410	2.629e-131	428.0	COG1167@1|root,COG1167@2|Bacteria,2G81Z@200795|Chloroflexi	200795|Chloroflexi	EK	PFAM Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
CMS1_k127_4118073_5	1123229.AUBC01000047_gene3803	4.271e-16	81.0	COG4126@1|root,COG4126@2|Bacteria,1MVNB@1224|Proteobacteria,2U28G@28211|Alphaproteobacteria,3JVNQ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Asp/Glu/Hydantoin racemase	MA20_32210	-	5.1.99.3	ko:K16841	ko00230,ko01120,map00230,map01120	-	R03925	RC01027	ko00000,ko00001,ko01000	-	-	-	Asp_Glu_race
CMS1_k127_4118073_4	865861.AZSU01000003_gene2104	2.557e-82	288.0	COG1228@1|root,COG1228@2|Bacteria,1TQQ0@1239|Firmicutes,24EHA@186801|Clostridia,36DKU@31979|Clostridiaceae	186801|Clostridia	Q	Psort location Cytoplasmic, score 7.50	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
CMS1_k127_4118073_0	1532558.JL39_17055	2.825e-182	587.0	COG0747@1|root,COG0747@2|Bacteria,1R59W@1224|Proteobacteria,2U7T7@28211|Alphaproteobacteria,4BC9V@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_4118073_2	1532558.JL39_17050	2.6e-122	400.0	COG0601@1|root,COG0601@2|Bacteria,1NH5E@1224|Proteobacteria,2U684@28211|Alphaproteobacteria,4BBG7@82115|Rhizobiaceae	28211|Alphaproteobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_4118073_3	1342301.JASD01000008_gene1981	6.312e-112	370.0	COG1173@1|root,COG1173@2|Bacteria,1RBAG@1224|Proteobacteria,2U6R4@28211|Alphaproteobacteria,3ZWMU@60136|Sulfitobacter	28211|Alphaproteobacteria	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
CMS1_k127_4118073_1	1118153.MOY_05510	2.947e-128	425.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,1RMEI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Belongs to the ABC transporter superfamily	sapF	GO:0000166,GO:0003674,GO:0005215,GO:0005488,GO:0005524,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008144,GO:0008150,GO:0008324,GO:0008519,GO:0009987,GO:0015075,GO:0015101,GO:0015203,GO:0015489,GO:0015672,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0017076,GO:0022857,GO:0030001,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034220,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071804,GO:0071805,GO:0072488,GO:0097159,GO:0097367,GO:0098655,GO:0098660,GO:0098662,GO:1901265,GO:1901363,GO:1902047	-	ko:K02031,ko:K02032,ko:K13896,ko:K19229,ko:K19230	ko01503,ko02010,ko02024,map01503,map02010,map02024	M00239,M00349,M00739	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.21,3.A.1.5.24,3.A.1.5.5	-	iYL1228.KPN_01288	ABC_tran,oligo_HPY
CMS1_k127_4124269_5	913865.DOT_4010	1.884e-05	56.0	COG0457@1|root,COG0457@2|Bacteria,1UUYP@1239|Firmicutes,24BRK@186801|Clostridia,2610N@186807|Peptococcaceae	186801|Clostridia	O	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_19,TPR_2,TPR_8
CMS1_k127_4124269_3	926550.CLDAP_39400	4.949e-41	160.0	COG0235@1|root,COG0235@2|Bacteria	2|Bacteria	G	Class ii aldolase	-	-	4.1.2.17,5.1.3.4	ko:K01628,ko:K03077	ko00040,ko00051,ko00053,ko01100,ko01120,map00040,map00051,map00053,map01100,map01120	M00550	R02262,R05850	RC00603,RC00604,RC01479	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
CMS1_k127_4124269_4	1110697.NCAST_32_09030	7.964e-21	101.0	2E0MB@1|root,32W6J@2|Bacteria,2IR53@201174|Actinobacteria,4FZRV@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4124269_2	1121106.JQKB01000047_gene4008	8.252e-50	192.0	COG4948@1|root,COG4948@2|Bacteria,1MXK7@1224|Proteobacteria,2TVB4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	mandelate racemase muconate lactonizing	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
CMS1_k127_4124269_0	1487921.DP68_07075	1.52e-82	282.0	COG1387@1|root,COG1387@2|Bacteria,1TQQX@1239|Firmicutes,247MM@186801|Clostridia,36GKW@31979|Clostridiaceae	186801|Clostridia	E	TIGRFAM histidinol phosphate phosphatase HisJ	hisK	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
CMS1_k127_4124269_1	426117.M446_2713	6.723e-75	256.0	COG0028@1|root,COG0028@2|Bacteria,1MX6Q@1224|Proteobacteria,2TR5N@28211|Alphaproteobacteria,1JRFY@119045|Methylobacteriaceae	28211|Alphaproteobacteria	EH	PFAM thiamine pyrophosphate protein domain protein TPP-binding	-	-	2.2.1.6,4.1.1.7	ko:K01576,ko:K01652	ko00290,ko00627,ko00650,ko00660,ko00770,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00290,map00627,map00650,map00660,map00770,map01100,map01110,map01120,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R01764,R02672,R03050,R04672,R04673,R08648	RC00027,RC00106,RC00595,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS1_k127_413387_0	1499967.BAYZ01000171_gene5534	1.126e-142	467.0	COG0589@1|root,COG1475@1|root,COG0589@2|Bacteria,COG1475@2|Bacteria,2NS1X@2323|unclassified Bacteria	2|Bacteria	K	DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF4032,ParBc,Usp
CMS1_k127_413387_6	621372.ACIH01000197_gene2592	2.864e-07	63.0	COG0477@1|root,COG2814@2|Bacteria,1TPW3@1239|Firmicutes,4H9R6@91061|Bacilli,26SHS@186822|Paenibacillaceae	91061|Bacilli	EGP	of the major facilitator superfamily	yfkF	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like,Sugar_tr
CMS1_k127_413387_3	1499967.BAYZ01000043_gene2310	2.168e-27	114.0	COG2886@1|root,COG2886@2|Bacteria	2|Bacteria	E	Uncharacterised protein family (UPF0175)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0175
CMS1_k127_413387_4	195250.CM001776_gene685	3.536e-23	100.0	2C72C@1|root,32Y9W@2|Bacteria,1G9PB@1117|Cyanobacteria,1H1VP@1129|Synechococcus	1117|Cyanobacteria	S	Domain of unknown function (DUF4926)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4926
CMS1_k127_413387_1	926560.KE387023_gene3595	4.119e-101	372.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,1WMBC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,TPR_12
CMS1_k127_413387_2	1128421.JAGA01000002_gene1680	3.557e-53	216.0	COG0515@1|root,COG0515@2|Bacteria,2NQWH@2323|unclassified Bacteria	2|Bacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_8
CMS1_k127_413387_5	335283.Neut_1379	8.963e-12	75.0	COG0265@1|root,COG0308@1|root,COG2234@1|root,COG0265@2|Bacteria,COG0308@2|Bacteria,COG2234@2|Bacteria,1MV86@1224|Proteobacteria,2WEJA@28216|Betaproteobacteria,374P7@32003|Nitrosomonadales	28216|Betaproteobacteria	EO	pdz dhr glgf	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M1,Peptidase_M28
CMS1_k127_4135143_5	926569.ANT_19080	4.56e-08	61.0	COG0593@1|root,COG0593@2|Bacteria,2G5W8@200795|Chloroflexi	200795|Chloroflexi	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
CMS1_k127_4135143_4	926569.ANT_24330	7.331e-13	80.0	COG0593@1|root,COG0593@2|Bacteria	2|Bacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N,Y1_Tnp
CMS1_k127_4135143_2	350688.Clos_1924	9.147e-41	161.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,247R1@186801|Clostridia,36H17@31979|Clostridiaceae	186801|Clostridia	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
CMS1_k127_4135143_6	358220.C380_00040	1.182e-07	58.0	COG0526@1|root,COG0526@2|Bacteria,1QTY9@1224|Proteobacteria,2VRG2@28216|Betaproteobacteria,4AJAS@80864|Comamonadaceae	28216|Betaproteobacteria	CO	PFAM Redoxin domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
CMS1_k127_4135143_3	639283.Snov_0827	3.381e-33	131.0	COG0526@1|root,COG0785@1|root,COG0526@2|Bacteria,COG0785@2|Bacteria,1MVV0@1224|Proteobacteria,2TUNG@28211|Alphaproteobacteria,3F1TP@335928|Xanthobacteraceae	28211|Alphaproteobacteria	O	Cytochrome C biogenesis protein transmembrane region	MA20_22750	-	-	-	-	-	-	-	-	-	-	-	DsbD
CMS1_k127_4135143_1	926550.CLDAP_00720	9.26e-77	262.0	COG4122@1|root,COG4122@2|Bacteria	2|Bacteria	E	O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
CMS1_k127_4135143_0	1123242.JH636435_gene1673	2.161e-141	459.0	COG1092@1|root,COG1092@2|Bacteria,2J1TU@203682|Planctomycetes	203682|Planctomycetes	J	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
CMS1_k127_4135143_7	926550.CLDAP_16480	6.321e-07	57.0	COG0745@1|root,COG1672@1|root,COG0745@2|Bacteria,COG1672@2|Bacteria,2G778@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
CMS1_k127_4169720_0	383372.Rcas_2537	4.466e-214	690.0	COG0577@1|root,COG0577@2|Bacteria,2G68F@200795|Chloroflexi,376ZY@32061|Chloroflexia	32061|Chloroflexia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS1_k127_4169720_1	439235.Dalk_2094	7.669e-141	476.0	COG0664@1|root,COG1752@1|root,COG0664@2|Bacteria,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,42RSN@68525|delta/epsilon subdivisions,2WNDI@28221|Deltaproteobacteria,2MPUY@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin,cNMP_binding
CMS1_k127_4169720_3	47839.CCAU010000001_gene3096	1.233e-15	81.0	COG4319@1|root,COG4319@2|Bacteria,2IPRQ@201174|Actinobacteria,23AH0@1762|Mycobacteriaceae	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
CMS1_k127_4169720_4	243272.MARTH_orf091	2.659e-08	62.0	COG3557@1|root,COG3557@2|Bacteria,3WTPJ@544448|Tenericutes	544448|Tenericutes	J	domain protein associated with RNAses G and E	-	-	-	ko:K07586	-	-	-	-	ko00000	-	-	-	DUF402
CMS1_k127_4169720_5	985255.APHJ01000039_gene124	3.558e-05	54.0	COG0813@1|root,COG0813@2|Bacteria,4NE52@976|Bacteroidetes,1HWNI@117743|Flavobacteriia,2P77C@244698|Gillisia	976|Bacteroidetes	F	Phosphorylase superfamily	deoD	-	2.4.2.1	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
CMS1_k127_4169720_2	1265505.ATUG01000002_gene1171	8.714e-117	407.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,1MWPD@1224|Proteobacteria,434EE@68525|delta/epsilon subdivisions,2WYRT@28221|Deltaproteobacteria,2MN3I@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD
CMS1_k127_4170941_11	926550.CLDAP_26360	9.073e-26	121.0	COG5276@1|root,COG5295@1|root,COG5276@2|Bacteria,COG5295@2|Bacteria,2G7I4@200795|Chloroflexi	200795|Chloroflexi	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4170941_15	1122927.KB895419_gene2345	5.705e-06	59.0	COG2366@1|root,COG3525@1|root,COG4099@1|root,COG5492@1|root,COG2366@2|Bacteria,COG3525@2|Bacteria,COG4099@2|Bacteria,COG5492@2|Bacteria,1TQ3T@1239|Firmicutes,4IQDX@91061|Bacilli,276CY@186822|Paenibacillaceae	91061|Bacilli	G	Glycosyl hydrolase family 20, domain 2	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	F5_F8_type_C,Glyco_hydro_20,Glyco_hydro_20b,Laminin_G_3
CMS1_k127_4170941_9	926550.CLDAP_26360	2.976e-30	133.0	COG5276@1|root,COG5295@1|root,COG5276@2|Bacteria,COG5295@2|Bacteria,2G7I4@200795|Chloroflexi	200795|Chloroflexi	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4170941_16	1174684.EBMC1_08000	0.0001875	53.0	COG4675@1|root,COG4675@2|Bacteria,1RESM@1224|Proteobacteria,2UQQX@28211|Alphaproteobacteria,2K578@204457|Sphingomonadales	204457|Sphingomonadales	S	tail collar domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4170941_13	1304865.JAGF01000001_gene2449	7.165e-14	83.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
CMS1_k127_4170941_7	1441930.Z042_18490	1.99e-35	146.0	COG2227@1|root,COG2227@2|Bacteria,1QYHT@1224|Proteobacteria,1T3QK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Methyltransferase small domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS1_k127_4170941_2	926569.ANT_07850	7.214e-101	334.0	COG2120@1|root,COG2120@2|Bacteria,2G6FB@200795|Chloroflexi	200795|Chloroflexi	S	PFAM LmbE family protein	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
CMS1_k127_4170941_10	1379698.RBG1_1C00001G1772	1.921e-29	127.0	COG0457@1|root,COG0457@2|Bacteria,2NQ3H@2323|unclassified Bacteria	2|Bacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2
CMS1_k127_4170941_6	1499967.BAYZ01000152_gene1397	4.414e-67	250.0	COG0457@1|root,COG0457@2|Bacteria,2NP5J@2323|unclassified Bacteria	2|Bacteria	S	Oxygen tolerance	-	-	-	-	-	-	-	-	-	-	-	-	BatD
CMS1_k127_4170941_12	316274.Haur_4899	7.292e-21	102.0	COG0457@1|root,COG0457@2|Bacteria	316274.Haur_4899|-	S	peptidyl-tyrosine sulfation	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	-
CMS1_k127_4170941_4	1379698.RBG1_1C00001G1774	1.18e-87	301.0	COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,2NP2F@2323|unclassified Bacteria	2|Bacteria	S	von Willebrand factor (vWF) type A domain	batB	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
CMS1_k127_4170941_5	880073.Calab_2474	1.585e-73	259.0	COG2304@1|root,COG2304@2|Bacteria,2NNYH@2323|unclassified Bacteria	2|Bacteria	NU	von Willebrand factor (vWF) type A domain	batA	-	-	ko:K07114,ko:K12511	-	-	-	-	ko00000,ko02000,ko02044	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
CMS1_k127_4170941_14	1517682.HW49_04080	3.42e-13	81.0	COG3088@1|root,COG3088@2|Bacteria,4NGHU@976|Bacteroidetes,2FP8Y@200643|Bacteroidia,22XR6@171551|Porphyromonadaceae	976|Bacteroidetes	O	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4170941_3	880073.Calab_2467	2.076e-100	335.0	COG1721@1|root,COG1721@2|Bacteria,2NNQI@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function DUF58	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF58
CMS1_k127_4170941_0	448385.sce6501	1.842e-130	424.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,42NCX@68525|delta/epsilon subdivisions,2WJUZ@28221|Deltaproteobacteria,2YUJY@29|Myxococcales	28221|Deltaproteobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS1_k127_4170941_8	926550.CLDAP_12950	1.627e-30	126.0	COG3695@1|root,COG3695@2|Bacteria,2G7CY@200795|Chloroflexi	200795|Chloroflexi	L	PFAM Methylated-DNA- protein -cysteine S-methyltransferase DNA binding	-	-	-	ko:K07443	-	-	-	-	ko00000	-	-	-	DNA_binding_1
CMS1_k127_4170941_1	1304865.JAGF01000001_gene3272	4.341e-114	377.0	COG1063@1|root,COG1063@2|Bacteria,2GKC7@201174|Actinobacteria	201174|Actinobacteria	E	alcohol dehydrogenase	-	-	1.1.1.14,1.1.1.303,1.1.1.4	ko:K00004,ko:K00008	ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100	M00014	R00875,R01896,R02855,R02946,R10504	RC00085,RC00102,RC00205,RC00525	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_417096_5	1123487.KB892865_gene1503	2.764e-61	216.0	COG0673@1|root,COG0673@2|Bacteria,1MXUP@1224|Proteobacteria,2VIRJ@28216|Betaproteobacteria,2KYJV@206389|Rhodocyclales	206389|Rhodocyclales	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	1.1.1.312	ko:K10219	ko00350,ko00362,ko00627,ko01120,ko01220,map00350,map00362,map00627,map01120,map01220	M00533	R04278,R04279,R04418,R04419	RC00251,RC00254	ko00000,ko00001,ko00002,ko01000	-	-	-	GFO_IDH_MocA
CMS1_k127_417096_2	316274.Haur_3199	5.032e-91	312.0	28SH2@1|root,2ZETH@2|Bacteria	2|Bacteria	S	Uncharacterized protein conserved in bacteria (DUF2236)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2236
CMS1_k127_417096_0	329726.AM1_2452	1.9e-322	1035.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1G335@1117|Cyanobacteria	1117|Cyanobacteria	T	SMART Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
CMS1_k127_417096_4	926550.CLDAP_38480	1.073e-77	263.0	COG4032@1|root,COG4032@2|Bacteria,2G8KU@200795|Chloroflexi	200795|Chloroflexi	S	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	-	-	4.1.1.79	ko:K06034	ko00680,ko01120,map00680,map01120	M00358	R05774	RC00506	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_N
CMS1_k127_417096_3	926550.CLDAP_38490	4.993e-87	290.0	COG0028@1|root,COG0028@2|Bacteria,2G8MK@200795|Chloroflexi	200795|Chloroflexi	EH	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C
CMS1_k127_417096_1	926550.CLDAP_38500	3.292e-128	414.0	COG1878@1|root,COG1878@2|Bacteria,2G6WM@200795|Chloroflexi	200795|Chloroflexi	S	PFAM cyclase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
CMS1_k127_417096_6	1173027.Mic7113_0883	7.637e-50	183.0	COG3292@1|root,COG3829@1|root,COG3920@1|root,COG3292@2|Bacteria,COG3829@2|Bacteria,COG3920@2|Bacteria,1GCAC@1117|Cyanobacteria,1HEG6@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Reg_prop,Response_reg,Y_Y_Y
CMS1_k127_4187463_1	1121472.AQWN01000001_gene168	2.353e-34	135.0	COG1489@1|root,COG1489@2|Bacteria,1V1GZ@1239|Firmicutes,24A0M@186801|Clostridia,2626X@186807|Peptococcaceae	186801|Clostridia	S	Belongs to the SfsA family	sfsA	-	-	ko:K06206	-	-	-	-	ko00000	-	-	-	SfsA
CMS1_k127_4187463_2	118173.KB235914_gene2547	1.475e-17	84.0	COG1476@1|root,COG1476@2|Bacteria,1GFFE@1117|Cyanobacteria,1HG93@1150|Oscillatoriales	1117|Cyanobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
CMS1_k127_4187463_4	195250.CM001776_gene2818	1.184e-09	66.0	COG2442@1|root,COG2442@2|Bacteria,1G7CJ@1117|Cyanobacteria	1117|Cyanobacteria	S	InterPro IPR007367	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4187463_3	211165.AJLN01000042_gene519	1.143e-15	81.0	2DNAA@1|root,32WEP@2|Bacteria,1G8A9@1117|Cyanobacteria,1JMBD@1189|Stigonemataceae	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4187463_0	234267.Acid_1816	1.702e-120	393.0	COG0178@1|root,COG0178@2|Bacteria,3Y3G9@57723|Acidobacteria	2|Bacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
CMS1_k127_4189763_6	1111728.ATYS01000005_gene1018	4.76e-23	102.0	2CBVU@1|root,3324G@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4418)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4418
CMS1_k127_4189763_1	292459.STH855	3.008e-71	257.0	COG0577@1|root,COG0577@2|Bacteria,1UYZ9@1239|Firmicutes,2484S@186801|Clostridia	186801|Clostridia	V	Efflux ABC transporter, permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS1_k127_4189763_2	456442.Mboo_0165	1.494e-60	217.0	COG1136@1|root,arCOG00922@2157|Archaea,2XUH3@28890|Euryarchaeota,2N9GV@224756|Methanomicrobia	224756|Methanomicrobia	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_4189763_0	309799.DICTH_0179	1.636e-127	418.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	ko:K20952	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Beta-prism_lec,PQQ_2,PQQ_3,Pkinase,VCBS
CMS1_k127_4189763_5	118005.AWNK01000010_gene334	8.03e-25	108.0	COG4633@1|root,COG4633@2|Bacteria	2|Bacteria	-	-	silP	-	1.9.3.1,3.6.3.54	ko:K02275,ko:K17686	ko00190,ko01100,ko01524,ko04016,map00190,map01100,map01524,map04016	M00155	R00081,R00086	RC00002,RC00016	ko00000,ko00001,ko00002,ko01000	3.A.3.5,3.D.4.2,3.D.4.4,3.D.4.6	-	-	Cupredoxin_1,DsbD_2,HMA
CMS1_k127_4189763_4	485913.Krac_6225	1.416e-34	139.0	COG0500@1|root,COG2226@2|Bacteria,2G8IB@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
CMS1_k127_4189763_3	479434.Sthe_1950	1.879e-50	193.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2G5Q5@200795|Chloroflexi,27Y10@189775|Thermomicrobia	200795|Chloroflexi	EU	PFAM peptidase S9 prolyl oligopeptidase active site domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
CMS1_k127_419767_9	1122915.AUGY01000065_gene5608	1.899e-91	303.0	COG5285@1|root,COG5285@2|Bacteria	2|Bacteria	Q	dioxygenase activity	-	-	-	ko:K18565	ko00332,ko01130,map00332,map01130	-	R10740,R10741,R10742	RC03267,RC03268,RC03269	ko00000,ko00001,ko01000	-	-	-	PhyH
CMS1_k127_419767_14	1123242.JH636434_gene5554	3.698e-88	304.0	COG0673@1|root,COG0673@2|Bacteria,2IYB5@203682|Planctomycetes	2|Bacteria	S	PFAM oxidoreductase	ophB	-	1.3.1.64	ko:K18067	ko00624,ko01100,ko01120,ko01220,map00624,map01100,map01120,map01220	M00623	R05275	RC00386	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_419767_11	1385511.N783_00270	1.087e-90	307.0	COG3608@1|root,COG3608@2|Bacteria	2|Bacteria	G	succinylglutamate desuccinylase aspartoacylase	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
CMS1_k127_419767_18	1504981.KO116_4135	2.011e-44	169.0	COG1335@1|root,COG1335@2|Bacteria,1MV0W@1224|Proteobacteria,1RQJ7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Isochorismatase hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
CMS1_k127_419767_12	1385511.N783_00275	2.255e-89	304.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4HBB9@91061|Bacilli,2Y8V6@289201|Pontibacillus	91061|Bacilli	U	ABC transporter permease	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1,OppC_N
CMS1_k127_419767_6	1307436.PBF_16419	4.426e-102	341.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,4HATR@91061|Bacilli,1ZCAV@1386|Bacillus	91061|Bacilli	P	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components	appB	GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0022857,GO:0051179,GO:0051234,GO:0055085	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_419767_3	1307436.PBF_16424	6.231e-157	511.0	COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,4HARF@91061|Bacilli,1ZC4E@1386|Bacillus	91061|Bacilli	E	COG0747 ABC-type dipeptide transport system, periplasmic component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_419767_17	986075.CathTA2_3012	1.5e-48	183.0	COG1414@1|root,COG1414@2|Bacteria,1TRMW@1239|Firmicutes,4HCSI@91061|Bacilli	91061|Bacilli	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
CMS1_k127_419767_2	1499967.BAYZ01000151_gene1662	7.236e-167	536.0	COG0534@1|root,COG0534@2|Bacteria,2NP6T@2323|unclassified Bacteria	2|Bacteria	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
CMS1_k127_419767_19	349521.HCH_04239	2.247e-44	180.0	COG2936@1|root,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,1RN7H@1236|Gammaproteobacteria,1XM3D@135619|Oceanospirillales	135619|Oceanospirillales	S	Peptidase S15	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
CMS1_k127_419767_20	797299.HALLA_04525	6.581e-28	122.0	COG4813@1|root,arCOG08124@2157|Archaea,2Y7IJ@28890|Euryarchaeota,241I1@183963|Halobacteria	183963|Halobacteria	G	Trehalose utilisation	-	-	-	ko:K09992	-	-	-	-	ko00000	-	-	-	ThuA
CMS1_k127_419767_16	1429916.X566_18465	7.897e-71	253.0	COG2055@1|root,COG2055@2|Bacteria,1MWQY@1224|Proteobacteria,2TR37@28211|Alphaproteobacteria,3JVES@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Malate/L-lactate dehydrogenase	MA20_06110	-	1.1.1.350	ko:K00073,ko:K13574	ko00230,ko01120,map00230,map01120	-	R02935,R02936	RC00169	ko00000,ko00001,ko01000	-	-	-	Ldh_2
CMS1_k127_419767_1	1144275.COCOR_01292	4.117e-181	585.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,42N2U@68525|delta/epsilon subdivisions,2WJRR@28221|Deltaproteobacteria,2YXAZ@29|Myxococcales	28221|Deltaproteobacteria	P	ABC transporter transmembrane region	msbA1	-	-	ko:K06147,ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS1_k127_419767_0	357808.RoseRS_2719	1.999e-219	695.0	COG1132@1|root,COG1132@2|Bacteria,2G5QH@200795|Chloroflexi,377YK@32061|Chloroflexia	32061|Chloroflexia	P	PFAM ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS1_k127_419767_8	309800.C498_01345	1.836e-91	309.0	COG3386@1|root,arCOG05370@2157|Archaea	2157|Archaea	G	SMP-30 Gluconolaconase	-	-	-	ko:K14274	ko00040,map00040	-	R02427	RC00713	ko00000,ko00001,ko01000	-	-	-	SGL
CMS1_k127_419767_4	526227.Mesil_2408	8.238e-123	411.0	COG1574@1|root,COG1574@2|Bacteria,1WINV@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
CMS1_k127_419767_15	1380763.BG53_05610	1.079e-77	268.0	COG1082@1|root,COG1082@2|Bacteria,1VXMT@1239|Firmicutes,4I7IE@91061|Bacilli,26WWM@186822|Paenibacillaceae	91061|Bacilli	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS1_k127_419767_10	428125.CLOLEP_02326	7.431e-91	312.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	1.1.99.28	ko:K00118	-	-	-	-	ko00000,ko01000	-	-	-	GFO_IDH_MocA
CMS1_k127_419767_7	357808.RoseRS_4254	9.847e-96	328.0	COG3964@1|root,COG3964@2|Bacteria,2G7WR@200795|Chloroflexi	200795|Chloroflexi	S	Amidohydrolase family	-	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
CMS1_k127_419767_13	1429916.X566_14890	3.251e-88	299.0	COG0179@1|root,COG0179@2|Bacteria,1R7SI@1224|Proteobacteria,2VFC0@28211|Alphaproteobacteria,3K3FV@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
CMS1_k127_419767_21	926569.ANT_08280	1.137e-11	76.0	COG0673@1|root,COG0673@2|Bacteria,2G8AS@200795|Chloroflexi	200795|Chloroflexi	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_419767_5	64471.sync_0860	4.466e-109	358.0	COG1028@1|root,COG1028@2|Bacteria,1GPIE@1117|Cyanobacteria,1H3BI@1129|Synechococcus	1117|Cyanobacteria	C	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS1_k127_419767_22	1267535.KB906767_gene4663	4.319e-06	50.0	COG4948@1|root,COG4948@2|Bacteria,3Y7D6@57723|Acidobacteria	57723|Acidobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
CMS1_k127_4199420_3	357804.Ping_3145	2.112e-47	176.0	COG0494@1|root,COG0494@2|Bacteria,1RHH9@1224|Proteobacteria,1S8DK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS1_k127_4199420_4	1268068.PG5_36550	7.214e-25	108.0	COG0642@1|root,COG2205@2|Bacteria,1MW8M@1224|Proteobacteria,1RNDA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	member of a two-component regulatory system	copS	-	2.7.13.3	ko:K07644	ko02020,map02020	M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	HAMP,HATPase_c,HisKA
CMS1_k127_4199420_0	926569.ANT_09340	2.068e-98	335.0	COG0265@1|root,COG0265@2|Bacteria,2G6KG@200795|Chloroflexi	200795|Chloroflexi	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	1.3.1.74,3.4.21.107	ko:K04771,ko:K08070	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
CMS1_k127_4199420_5	1117108.PAALTS15_02912	7.389e-24	109.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,4HIRK@91061|Bacilli,26X19@186822|Paenibacillaceae	91061|Bacilli	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
CMS1_k127_4199420_1	357808.RoseRS_3094	1.527e-94	319.0	COG0484@1|root,COG0484@2|Bacteria,2G61V@200795|Chloroflexi,37696@32061|Chloroflexia	32061|Chloroflexia	O	PFAM heat shock protein DnaJ domain protein	-	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
CMS1_k127_4199420_2	926550.CLDAP_24450	1.089e-63	237.0	2EZVX@1|root,33T0B@2|Bacteria,2G87X@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_420663_2	765952.PUV_21420	3.834e-22	103.0	COG0572@1|root,COG0572@2|Bacteria	2|Bacteria	F	uridine kinase	-	-	2.7.1.48,3.1.3.18	ko:K00876,ko:K01091	ko00240,ko00630,ko00983,ko01100,ko01110,ko01130,map00240,map00630,map00983,map01100,map01110,map01130	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01334,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	AAA_18,PRK
CMS1_k127_420663_1	696747.NIES39_O05150	1.258e-60	224.0	COG0515@1|root,COG1520@1|root,COG0515@2|Bacteria,COG1520@2|Bacteria,1G7CP@1117|Cyanobacteria	1117|Cyanobacteria	KLT	PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
CMS1_k127_420663_0	926550.CLDAP_01230	1.517e-84	302.0	COG3463@1|root,COG3463@2|Bacteria,2G8G9@200795|Chloroflexi	200795|Chloroflexi	S	Predicted membrane protein (DUF2079)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2079
CMS1_k127_421378_7	926550.CLDAP_09690	5.273e-24	110.0	COG4485@1|root,COG4485@2|Bacteria,2G75F@200795|Chloroflexi	200795|Chloroflexi	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
CMS1_k127_421378_0	926569.ANT_15160	5.096e-176	576.0	COG0515@1|root,COG1520@1|root,COG0515@2|Bacteria,COG1520@2|Bacteria,2G5NM@200795|Chloroflexi	200795|Chloroflexi	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PQQ_3,Pkinase
CMS1_k127_421378_5	926569.ANT_15150	6.566e-56	207.0	COG0631@1|root,COG0631@2|Bacteria,2G8RD@200795|Chloroflexi	200795|Chloroflexi	T	SMART protein phosphatase 2C domain protein	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
CMS1_k127_421378_2	765420.OSCT_2728	2.303e-67	245.0	COG2304@1|root,COG2304@2|Bacteria,2G8H5@200795|Chloroflexi,374V6@32061|Chloroflexia	32061|Chloroflexia	S	PFAM von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
CMS1_k127_421378_6	1128421.JAGA01000002_gene182	1.957e-26	116.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	DZR,FHA,zinc_ribbon_2
CMS1_k127_421378_8	765420.OSCT_2726	4.777e-18	85.0	2EMHG@1|root,33F64@2|Bacteria,2G7IC@200795|Chloroflexi,375VD@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_421378_3	383372.Rcas_2656	8.413e-63	233.0	2DMUC@1|root,32TQR@2|Bacteria,2G6MF@200795|Chloroflexi,374YD@32061|Chloroflexia	32061|Chloroflexia	S	CpXC protein	-	-	-	-	-	-	-	-	-	-	-	-	CpXC
CMS1_k127_421378_4	926550.CLDAP_23360	4.449e-57	205.0	COG0745@1|root,COG1716@1|root,COG0745@2|Bacteria,COG1716@2|Bacteria,2G8QX@200795|Chloroflexi	200795|Chloroflexi	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
CMS1_k127_421378_1	926569.ANT_13330	7.09e-108	359.0	COG0515@1|root,COG0515@2|Bacteria,2G850@200795|Chloroflexi	200795|Chloroflexi	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS1_k127_4222351_8	1229172.JQFA01000005_gene190	1.928e-27	117.0	COG0745@1|root,COG0745@2|Bacteria,1G2ME@1117|Cyanobacteria,1H95X@1150|Oscillatoriales	1117|Cyanobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_4222351_0	266117.Rxyl_2612	4.91e-139	452.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2I312@201174|Actinobacteria,4CRWF@84995|Rubrobacteria	84995|Rubrobacteria	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	2.7.13.3	ko:K02480	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA_3
CMS1_k127_4222351_3	1382306.JNIM01000001_gene3919	9.126e-78	266.0	COG2197@1|root,COG2197@2|Bacteria,2G6JC@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS1_k127_4222351_11	649831.L083_3499	2.958e-13	74.0	2EG61@1|root,339XX@2|Bacteria,2IMU8@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4222351_1	228410.NE2038	9.532e-135	442.0	COG2373@1|root,COG2373@2|Bacteria,1QXEG@1224|Proteobacteria	1224|Proteobacteria	S	Animal haem peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	An_peroxidase
CMS1_k127_4222351_12	1305735.JAFT01000005_gene3041	6.608e-09	67.0	COG0261@1|root,COG3743@1|root,COG0261@2|Bacteria,COG3743@2|Bacteria,1MZEW@1224|Proteobacteria,2UBT3@28211|Alphaproteobacteria,2PD8U@252301|Oceanicola	28211|Alphaproteobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	HHH_5,Ribosomal_L21p
CMS1_k127_4222351_9	33876.JNXY01000041_gene6470	1.633e-16	85.0	2B351@1|root,31VST@2|Bacteria,2GW63@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4222351_5	649831.L083_3500	1.105e-53	202.0	COG3629@1|root,COG3629@2|Bacteria,2I5I3@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
CMS1_k127_4222351_6	383372.Rcas_2803	1.876e-32	134.0	COG0640@1|root,COG3860@1|root,COG0640@2|Bacteria,COG3860@2|Bacteria,2G8TH@200795|Chloroflexi,377X2@32061|Chloroflexia	32061|Chloroflexia	K	Uncharacterized protein conserved in bacteria (DUF2087)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2087,HTH_5
CMS1_k127_4222351_4	1173026.Glo7428_2849	1.741e-75	257.0	COG0640@1|root,COG3860@1|root,COG0640@2|Bacteria,COG3860@2|Bacteria,1G59V@1117|Cyanobacteria	1117|Cyanobacteria	K	protein conserved in bacteria (DUF2087)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2087,HTH_5
CMS1_k127_4222351_7	316274.Haur_0593	6.175e-30	123.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,2GA6X@200795|Chloroflexi,375DW@32061|Chloroflexia	32061|Chloroflexia	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
CMS1_k127_4222351_2	211114.JOEF01000004_gene6604	3.04e-98	337.0	28XJV@1|root,2ZJGZ@2|Bacteria,2I3N6@201174|Actinobacteria,4E08F@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4222351_10	1121904.ARBP01000009_gene4242	1.323e-13	76.0	COG2867@1|root,COG2867@2|Bacteria,4NZC8@976|Bacteroidetes,47WXU@768503|Cytophagia	976|Bacteroidetes	I	negative regulation of translational initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4229445_0	1499967.BAYZ01000177_gene5755	4.559e-225	708.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2NNS9@2323|unclassified Bacteria	2|Bacteria	EU	peptidase S9 prolyl oligopeptidase active site	yuxL	-	3.4.19.1	ko:K01303	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S9
CMS1_k127_4229445_1	570268.ANBB01000014_gene5357	1.106e-117	389.0	COG0665@1|root,COG0665@2|Bacteria,2GNAE@201174|Actinobacteria	201174|Actinobacteria	E	PFAM FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
CMS1_k127_4229445_2	926550.CLDAP_15580	6.038e-91	309.0	COG1159@1|root,COG1159@2|Bacteria,2G69C@200795|Chloroflexi	200795|Chloroflexi	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
CMS1_k127_4229445_4	56780.SYN_01967	1.484e-51	185.0	COG0780@1|root,COG0780@2|Bacteria,1MW0M@1224|Proteobacteria,42RDZ@68525|delta/epsilon subdivisions,2WQ4Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K06879,ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
CMS1_k127_4229445_3	1219035.NT2_01_06320	2.034e-85	289.0	COG1738@1|root,COG1738@2|Bacteria,1NIPE@1224|Proteobacteria,2TTZV@28211|Alphaproteobacteria,2K1FS@204457|Sphingomonadales	204457|Sphingomonadales	S	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
CMS1_k127_423068_2	1462527.CCDM010000001_gene2904	8.049e-19	99.0	COG1160@1|root,COG3597@1|root,COG1160@2|Bacteria,COG3597@2|Bacteria,1TSZW@1239|Firmicutes,4HCAY@91061|Bacilli,23J5E@182709|Oceanobacillus	91061|Bacilli	S	Domain of unknown function (DUF697)	-	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	DUF697,MMR_HSR1
CMS1_k127_423068_1	671143.DAMO_0981	7.22e-226	711.0	COG1013@1|root,COG1145@1|root,COG1013@2|Bacteria,COG1145@2|Bacteria,2NQV4@2323|unclassified Bacteria	2|Bacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
CMS1_k127_423068_0	671143.DAMO_0980	6.789e-286	891.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2NP1J@2323|unclassified Bacteria	2|Bacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_13,Fer4_6,PFOR_II,POR,POR_N,TPP_enzyme_C
CMS1_k127_4238863_8	1499968.TCA2_2436	3.455e-10	64.0	COG0213@1|root,COG0213@2|Bacteria,1TPCH@1239|Firmicutes,4H9NP@91061|Bacilli,26QE9@186822|Paenibacillaceae	91061|Bacilli	F	Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate	pdp	GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464	2.4.2.2	ko:K00756	ko00240,ko01100,map00240,map01100	-	R01570,R01876,R02296,R02484	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
CMS1_k127_4238863_0	316274.Haur_1560	5.139e-201	631.0	COG1960@1|root,COG1960@2|Bacteria,2G5K3@200795|Chloroflexi,374SC@32061|Chloroflexia	200795|Chloroflexi	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS1_k127_4238863_1	666685.R2APBS1_0795	7.492e-179	569.0	COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,1RMP0@1236|Gammaproteobacteria,1X4KU@135614|Xanthomonadales	135614|Xanthomonadales	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CMS1_k127_4238863_7	357808.RoseRS_3512	2.081e-16	92.0	28UHB@1|root,2ZGN2@2|Bacteria,2G9K6@200795|Chloroflexi,377RV@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4238863_2	926550.CLDAP_02300	2.003e-121	415.0	COG5617@1|root,COG5617@2|Bacteria,2G8CQ@200795|Chloroflexi	200795|Chloroflexi	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4238863_6	714943.Mucpa_2851	1.007e-19	98.0	COG1011@1|root,COG1011@2|Bacteria,4NIMR@976|Bacteroidetes,1IPZN@117747|Sphingobacteriia	976|Bacteroidetes	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	3.8.1.2	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
CMS1_k127_4238863_9	1479623.JHEL01000015_gene797	1.576e-05	56.0	COG3173@1|root,COG3173@2|Bacteria,2HV2K@201174|Actinobacteria,4FS33@85023|Microbacteriaceae	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS1_k127_4238863_3	497965.Cyan7822_1404	3.714e-107	358.0	COG1051@1|root,COG1194@1|root,COG1051@2|Bacteria,COG1194@2|Bacteria,1G7MC@1117|Cyanobacteria,3KH3E@43988|Cyanothece	1117|Cyanobacteria	L	A G-specific adenine glycosylase	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
CMS1_k127_4238863_5	1499967.BAYZ01000184_gene4564	1.124e-45	174.0	COG1564@1|root,COG1564@2|Bacteria,2NPUG@2323|unclassified Bacteria	2|Bacteria	H	Thiamin pyrophosphokinase, vitamin B1 binding domain	thiN	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_B1_binding,TPK_catalytic
CMS1_k127_4238863_4	926569.ANT_06700	5.979e-98	329.0	COG4143@1|root,COG4143@2|Bacteria,2G615@200795|Chloroflexi	200795|Chloroflexi	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02064	ko02010,map02010	M00191	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.19	-	-	SBP_bac_6
CMS1_k127_4306507_4	391625.PPSIR1_14625	1.96e-19	98.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,42ZF8@68525|delta/epsilon subdivisions,2WUXM@28221|Deltaproteobacteria,2YUEW@29|Myxococcales	28221|Deltaproteobacteria	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
CMS1_k127_4306507_1	765420.OSCT_0728	3.258e-75	265.0	COG4585@1|root,COG4585@2|Bacteria,2G71C@200795|Chloroflexi,3752U@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	2.7.13.3	ko:K07777	ko02020,map02020	M00478	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DegS,HATPase_c,HisKA_3
CMS1_k127_4306507_0	309801.trd_1669	2.912e-76	261.0	COG2197@1|root,COG2197@2|Bacteria,2G6K0@200795|Chloroflexi,27Y3S@189775|Thermomicrobia	189775|Thermomicrobia	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS1_k127_4306507_3	373903.Hore_21830	8.405e-31	134.0	COG1196@1|root,COG4585@1|root,COG1196@2|Bacteria,COG4585@2|Bacteria,1TQI3@1239|Firmicutes,249R9@186801|Clostridia,3WB8N@53433|Halanaerobiales	186801|Clostridia	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	degS	-	2.7.13.3	ko:K07777	ko02020,map02020	M00478	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DegS,HATPase_c,HisKA_3
CMS1_k127_4306507_2	926569.ANT_11560	4.299e-44	164.0	COG1269@1|root,COG1269@2|Bacteria	2|Bacteria	C	ATP hydrolysis coupled proton transport	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS1_k127_432356_12	1521187.JPIM01000054_gene3102	4.859e-42	161.0	COG0705@1|root,COG0705@2|Bacteria,2G7BZ@200795|Chloroflexi,375SV@32061|Chloroflexia	32061|Chloroflexia	S	PFAM Rhomboid family protein	-	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
CMS1_k127_432356_1	1234664.AMRO01000072_gene3627	3.534e-162	546.0	COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,4H9WW@91061|Bacilli,1WEMW@129337|Geobacillus	91061|Bacilli	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
CMS1_k127_432356_19	685727.REQ_25100	0.000174	53.0	COG1846@1|root,COG1846@2|Bacteria,2GMDI@201174|Actinobacteria,4FVSD@85025|Nocardiaceae	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_432356_15	765420.OSCT_1795	4.725e-32	133.0	COG0526@1|root,COG0526@2|Bacteria,2G72F@200795|Chloroflexi,377HE@32061|Chloroflexia	32061|Chloroflexia	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS1_k127_432356_14	420246.GTNG_1407	2.404e-33	136.0	COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HJN1@91061|Bacilli,1WEHB@129337|Geobacillus	91061|Bacilli	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS1_k127_432356_17	635013.TherJR_2272	2.096e-22	106.0	COG0682@1|root,COG0682@2|Bacteria,1TPAK@1239|Firmicutes,24APG@186801|Clostridia,261Q5@186807|Peptococcaceae	186801|Clostridia	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
CMS1_k127_432356_13	926550.CLDAP_03020	3.361e-36	151.0	COG3764@1|root,COG3764@2|Bacteria,2G70I@200795|Chloroflexi	200795|Chloroflexi	M	peptidase C60 sortase A and B	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
CMS1_k127_432356_16	926569.ANT_30450	6.284e-29	122.0	28NSZ@1|root,337UE@2|Bacteria,2GA9H@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_432356_10	926569.ANT_30440	4.761e-47	181.0	COG1466@1|root,COG1466@2|Bacteria,2G6XX@200795|Chloroflexi	200795|Chloroflexi	L	TIGRFAM DNA polymerase III, delta' subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
CMS1_k127_432356_2	383372.Rcas_0299	9.085e-150	482.0	COG1168@1|root,COG1168@2|Bacteria,2G614@200795|Chloroflexi,375GA@32061|Chloroflexia	32061|Chloroflexia	E	PFAM aminotransferase, class I and II	-	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS1_k127_432356_0	1118054.CAGW01000053_gene1447	1.721e-203	651.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4H9TK@91061|Bacilli,26SV5@186822|Paenibacillaceae	91061|Bacilli	S	ABC transporter	yfmR	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
CMS1_k127_432356_4	926550.CLDAP_28180	4.299e-109	381.0	COG0642@1|root,COG0784@1|root,COG2204@1|root,COG0784@2|Bacteria,COG2204@2|Bacteria,COG2205@2|Bacteria,2G84W@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
CMS1_k127_432356_9	926550.CLDAP_28170	2.342e-49	192.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
CMS1_k127_432356_18	985665.HPL003_03180	1.626e-19	100.0	COG3221@1|root,COG3221@2|Bacteria,1TR0H@1239|Firmicutes,4HBJQ@91061|Bacilli,26TI5@186822|Paenibacillaceae	91061|Bacilli	P	ABC-type phosphate phosphonate transport system, periplasmic component	phnD	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
CMS1_k127_432356_6	1120950.KB892760_gene5740	4.297e-100	342.0	COG1653@1|root,COG1653@2|Bacteria,2HQR6@201174|Actinobacteria,4DTFS@85009|Propionibacteriales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
CMS1_k127_432356_7	1120950.KB892760_gene5738	7.659e-100	334.0	COG1175@1|root,COG1175@2|Bacteria,2GKBJ@201174|Actinobacteria,4DWRD@85009|Propionibacteriales	201174|Actinobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_432356_8	1120950.KB892760_gene5739	1.351e-87	298.0	COG0395@1|root,COG0395@2|Bacteria,2GMTH@201174|Actinobacteria,4DWRH@85009|Propionibacteriales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_432356_3	743719.PaelaDRAFT_4442	8.351e-111	370.0	COG2159@1|root,COG2159@2|Bacteria,1UZAH@1239|Firmicutes,4HA5S@91061|Bacilli,26SJA@186822|Paenibacillaceae	91061|Bacilli	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CMS1_k127_432356_11	333138.LQ50_24170	2.856e-43	162.0	COG2146@1|root,COG2146@2|Bacteria,1TU1F@1239|Firmicutes,4IM3H@91061|Bacilli,1ZJ0X@1386|Bacillus	91061|Bacilli	P	Rieske-like [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
CMS1_k127_432356_5	204669.Acid345_4386	2.987e-107	355.0	COG1649@1|root,COG1649@2|Bacteria,3Y2XT@57723|Acidobacteria,2JIYN@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM Uncharacterised BCR, COG1649	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4323649_3	1500301.JQMF01000038_gene5903	1.466e-53	200.0	COG0683@1|root,COG0683@2|Bacteria,1NHBN@1224|Proteobacteria,2TWTC@28211|Alphaproteobacteria,4BBUQ@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Periplasmic binding protein	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
CMS1_k127_4323649_11	235985.BBPN01000011_gene4296	0.0001663	48.0	COG1359@1|root,COG1359@2|Bacteria	2|Bacteria	S	Antibiotic biosynthesis monooxygenase	yjcS	GO:0003674,GO:0003824	-	-	-	-	-	-	-	-	-	-	ABM
CMS1_k127_4323649_0	1366050.N234_37045	2.916e-106	384.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2VKH1@28216|Betaproteobacteria,1JZT2@119060|Burkholderiaceae	28216|Betaproteobacteria	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
CMS1_k127_4323649_7	1040982.AXAL01000029_gene4283	7.189e-32	146.0	COG2267@1|root,COG3629@1|root,COG2267@2|Bacteria,COG3629@2|Bacteria,1NIJG@1224|Proteobacteria,2U09P@28211|Alphaproteobacteria,43PM5@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	IT	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,BTAD,Hydrolase_4,Trans_reg_C
CMS1_k127_4323649_5	649638.Trad_1778	5.845e-39	149.0	COG3744@1|root,COG3744@2|Bacteria,1WKBP@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
CMS1_k127_4323649_8	649638.Trad_1777	1.141e-21	98.0	COG4118@1|root,COG4118@2|Bacteria,1WKSW@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	D	Antitoxin Phd_YefM, type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
CMS1_k127_4323649_1	525904.Tter_2523	3.144e-105	350.0	COG1175@1|root,COG1175@2|Bacteria,2NQCB@2323|unclassified Bacteria	2|Bacteria	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025,ko:K05814,ko:K10118,ko:K10237,ko:K10241,ko:K15771,ko:K17235,ko:K17316	ko02010,map02010	M00196,M00198,M00204,M00206,M00207,M00491,M00602,M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.17,3.A.1.1.2,3.A.1.1.23,3.A.1.1.24,3.A.1.1.28,3.A.1.1.3,3.A.1.1.30,3.A.1.1.34	-	-	BPD_transp_1
CMS1_k127_4323649_2	525904.Tter_2522	4.46e-86	293.0	COG0395@1|root,COG0395@2|Bacteria,2NPII@2323|unclassified Bacteria	2|Bacteria	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02026,ko:K05815	ko02010,map02010	M00198,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.3	-	-	BPD_transp_1
CMS1_k127_4323649_6	66692.ABC3774	2.026e-34	149.0	COG1653@1|root,COG1653@2|Bacteria,1VSBH@1239|Firmicutes,4HTU3@91061|Bacilli,1ZEGS@1386|Bacillus	91061|Bacilli	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_8
CMS1_k127_4323649_10	314256.OG2516_05613	1.802e-07	53.0	COG0673@1|root,COG0673@2|Bacteria,1N0VK@1224|Proteobacteria,2TR13@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_4323649_9	153948.NAL212_0730	2.806e-08	58.0	28KEA@1|root,2ZA0J@2|Bacteria,1R5TS@1224|Proteobacteria,2WBU3@28216|Betaproteobacteria,373TA@32003|Nitrosomonadales	28216|Betaproteobacteria	H	PFAM Sulfotransferase	-	-	2.8.2.1	ko:K01014	ko05204,map05204	-	R01242	RC00007,RC00128	ko00000,ko00001,ko01000	-	-	-	Sulfotransfer_1
CMS1_k127_4323649_4	234267.Acid_1144	7.54e-52	186.0	COG3391@1|root,COG3391@2|Bacteria,3Y98W@57723|Acidobacteria	57723|Acidobacteria	S	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NHL
CMS1_k127_4335049_1	1487953.JMKF01000065_gene4648	7.452e-42	178.0	COG3629@1|root,COG3629@2|Bacteria,1G5W7@1117|Cyanobacteria	1117|Cyanobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,TPR_12
CMS1_k127_4335049_0	1173023.KE650771_gene3252	3.741e-150	509.0	COG2319@1|root,COG3903@1|root,COG2319@2|Bacteria,COG3903@2|Bacteria,1FZVW@1117|Cyanobacteria	1117|Cyanobacteria	A	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC,WD40
CMS1_k127_4336958_1	221288.JH992901_gene3415	1.482e-96	338.0	COG1672@1|root,COG2319@1|root,COG1672@2|Bacteria,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1JJ8I@1189|Stigonemataceae	1117|Cyanobacteria	S	AAA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_35,WD40
CMS1_k127_4336958_2	215803.DB30_6069	1.754e-91	329.0	COG1672@1|root,COG2319@1|root,COG1672@2|Bacteria,COG2319@2|Bacteria,1MWJA@1224|Proteobacteria,42P8D@68525|delta/epsilon subdivisions,2WMH1@28221|Deltaproteobacteria,2YXT4@29|Myxococcales	28221|Deltaproteobacteria	S	AAA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_35,Pkinase,WD40
CMS1_k127_4336958_0	373994.Riv7116_6098	3.226e-103	365.0	COG1672@1|root,COG1672@2|Bacteria,1G0F4@1117|Cyanobacteria,1HMJD@1161|Nostocales	1117|Cyanobacteria	K	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	AAA_35,CHAT,TIR_2
CMS1_k127_4336958_3	383372.Rcas_3701	3.804e-44	184.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GAAG@200795|Chloroflexi,374S4@32061|Chloroflexia	32061|Chloroflexia	K	transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,TPR_12,Trans_reg_C
CMS1_k127_433705_0	189425.PGRAT_19655	7.452e-37	143.0	COG2909@1|root,COG2909@2|Bacteria,1UIMV@1239|Firmicutes,4HD7H@91061|Bacilli,26QDM@186822|Paenibacillaceae	91061|Bacilli	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
CMS1_k127_433705_3	1173024.KI912148_gene2537	8.787e-06	58.0	COG0265@1|root,COG0457@1|root,COG0265@2|Bacteria,COG0457@2|Bacteria,1G46W@1117|Cyanobacteria	1117|Cyanobacteria	O	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8,Trypsin_2
CMS1_k127_433705_2	1122927.KB895412_gene776	1.14e-27	128.0	COG1595@1|root,COG1595@2|Bacteria,1V70Y@1239|Firmicutes,4HINM@91061|Bacilli,26T02@186822|Paenibacillaceae	91061|Bacilli	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoD3	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	DUF1835,Sigma70_r2,Sigma70_r4_2
CMS1_k127_433705_1	313612.L8106_12025	5.498e-33	130.0	COG0454@1|root,COG0456@2|Bacteria,1G8VD@1117|Cyanobacteria,1HGGD@1150|Oscillatoriales	1117|Cyanobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	ko:K03826	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_7
CMS1_k127_4345448_1	926550.CLDAP_39080	2.313e-169	539.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,2G5MU@200795|Chloroflexi	200795|Chloroflexi	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
CMS1_k127_4345448_5	1307761.L21SP2_0011	3.308e-47	173.0	COG0509@1|root,COG0509@2|Bacteria,2J8D7@203691|Spirochaetes	203691|Spirochaetes	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
CMS1_k127_4345448_2	926550.CLDAP_07520	2.562e-115	382.0	COG0404@1|root,COG0404@2|Bacteria,2G5VA@200795|Chloroflexi	200795|Chloroflexi	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
CMS1_k127_4345448_4	324602.Caur_1282	1.824e-50	190.0	COG0681@1|root,COG0681@2|Bacteria,2G701@200795|Chloroflexi,375E7@32061|Chloroflexia	32061|Chloroflexia	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
CMS1_k127_4345448_3	1211814.CAPG01000045_gene2440	3.052e-81	276.0	COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,4HAAJ@91061|Bacilli,1ZCZ6@1386|Bacillus	91061|Bacilli	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
CMS1_k127_4345448_9	697303.Thewi_0768	2.283e-05	49.0	2DR9H@1|root,33ASP@2|Bacteria,1VMWC@1239|Firmicutes,24V74@186801|Clostridia,42HF0@68295|Thermoanaerobacterales	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4345448_8	1196322.A370_01517	7.02e-22	99.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,36EKZ@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,Hpt,PAS_9,Response_reg,sCache_3_3
CMS1_k127_4345448_6	765420.OSCT_1933	2.363e-46	181.0	COG0745@1|root,COG4963@1|root,COG0745@2|Bacteria,COG4963@2|Bacteria,2G89B@200795|Chloroflexi,377XT@32061|Chloroflexia	200795|Chloroflexi	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	CBP_BcsQ,Response_reg
CMS1_k127_4345448_0	63737.Npun_F1222	4.944e-292	943.0	COG1672@1|root,COG2319@1|root,COG1672@2|Bacteria,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1HINJ@1161|Nostocales	1117|Cyanobacteria	L	PFAM WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,WD40
CMS1_k127_4345448_7	512565.AMIS_79660	4.325e-28	115.0	COG1680@1|root,COG1680@2|Bacteria,2GJJB@201174|Actinobacteria,4D9FK@85008|Micromonosporales	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS1_k127_440189_3	391612.CY0110_23356	4.032e-17	89.0	COG1833@1|root,COG1833@2|Bacteria,1GEFM@1117|Cyanobacteria,3KK05@43988|Cyanothece	1117|Cyanobacteria	S	Domain of unknown function DUF123	-	-	-	-	-	-	-	-	-	-	-	-	DUF123
CMS1_k127_440189_0	926569.ANT_14030	2.925e-201	647.0	COG0480@1|root,COG0480@2|Bacteria,2G680@200795|Chloroflexi	200795|Chloroflexi	J	elongation factor Tu domain 2 protein	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
CMS1_k127_440189_4	653045.Strvi_1653	1.245e-08	63.0	COG0457@1|root,COG3903@1|root,COG0457@2|Bacteria,COG3903@2|Bacteria,2GIRS@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator, SARP family	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC,TPR_12,TPR_7
CMS1_k127_440189_1	326427.Cagg_2820	3.573e-86	306.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G88D@200795|Chloroflexi,374V1@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA_3
CMS1_k127_440189_5	926569.ANT_13860	0.0004827	44.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
CMS1_k127_446416_2	479434.Sthe_3331	4.049e-34	134.0	2BVHN@1|root,32SWN@2|Bacteria,2G8ZV@200795|Chloroflexi	200795|Chloroflexi	S	Pfam:DUF385	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
CMS1_k127_446416_3	1499967.BAYZ01000068_gene1934	6.745e-07	57.0	COG5434@1|root,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,F5_F8_type_C,Glyco_hydro_28,Pectate_lyase_3,SdiA-regulated
CMS1_k127_446416_0	525904.Tter_0396	5.486e-89	301.0	COG2141@1|root,COG2141@2|Bacteria,2NQM2@2323|unclassified Bacteria	2|Bacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS1_k127_446416_1	102232.GLO73106DRAFT_00032890	1.901e-65	242.0	COG5305@1|root,COG5305@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS1_k127_4464292_2	357808.RoseRS_0650	2.459e-49	185.0	COG1203@1|root,COG1203@2|Bacteria,2G710@200795|Chloroflexi	200795|Chloroflexi	L	CRISPR-associated protein Cse1 (CRISPR_cse1)	-	-	-	ko:K19123	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_Cse1
CMS1_k127_4464292_0	357808.RoseRS_0651	1.189e-148	515.0	COG1203@1|root,COG1203@2|Bacteria,2G5RI@200795|Chloroflexi	200795|Chloroflexi	L	DEAD-like helicases superfamily	-	-	-	ko:K07012	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	-
CMS1_k127_4464292_1	867845.KI911784_gene3368	1.279e-62	247.0	COG2378@1|root,COG2378@2|Bacteria,2G9UN@200795|Chloroflexi,37763@32061|Chloroflexia	32061|Chloroflexia	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	WYL
CMS1_k127_4467709_3	1128421.JAGA01000001_gene2367	0.0008042	51.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase,DUF3471
CMS1_k127_4467709_1	316274.Haur_1928	8.132e-25	119.0	COG2931@1|root,COG3391@1|root,COG2931@2|Bacteria,COG3391@2|Bacteria,2GBI9@200795|Chloroflexi,377IY@32061|Chloroflexia	32061|Chloroflexia	Q	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
CMS1_k127_4467709_2	471853.Bcav_3390	0.0001795	53.0	COG2730@1|root,COG3537@1|root,COG4225@1|root,COG2730@2|Bacteria,COG3537@2|Bacteria,COG4225@2|Bacteria	2|Bacteria	S	unsaturated chondroitin disaccharide hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4962,F5_F8_type_C,Hepar_II_III,Ricin_B_lectin
CMS1_k127_4467709_0	697282.Mettu_2045	1.941e-45	180.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,1XFQY@135618|Methylococcales	135618|Methylococcales	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
CMS1_k127_4493334_0	1167006.UWK_01309	1.089e-218	694.0	COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,1MUEA@1224|Proteobacteria,42MER@68525|delta/epsilon subdivisions,2WIYV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
CMS1_k127_4493334_1	1167006.UWK_01323	6.208e-189	598.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,42M1W@68525|delta/epsilon subdivisions,2WK53@28221|Deltaproteobacteria,2MIJV@213118|Desulfobacterales	28221|Deltaproteobacteria	E	TIGRFAM threonine synthase	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS1_k127_4493334_2	926550.CLDAP_10970	1.01e-127	409.0	COG0078@1|root,COG0078@2|Bacteria,2G7QE@200795|Chloroflexi	200795|Chloroflexi	E	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	-	-	2.1.3.9	ko:K09065	ko00220,ko01100,ko01230,map00220,map01100,map01230	M00845	R07245	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
CMS1_k127_449340_5	331869.BAL199_28815	6.865e-11	72.0	COG5285@1|root,COG5285@2|Bacteria,1R84J@1224|Proteobacteria	1224|Proteobacteria	Q	COG5285 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
CMS1_k127_449340_6	1304880.JAGB01000001_gene916	6.382e-07	62.0	COG2182@1|root,COG2182@2|Bacteria,1UI6V@1239|Firmicutes	1239|Firmicutes	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
CMS1_k127_449340_3	604331.AUHY01000032_gene2502	6.043e-55	204.0	COG1175@1|root,COG1175@2|Bacteria,1WJ21@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_449340_2	926550.CLDAP_23080	1.123e-70	249.0	COG0395@1|root,COG0395@2|Bacteria	2|Bacteria	P	glycerophosphodiester transmembrane transport	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_449340_1	383372.Rcas_3851	5.761e-111	365.0	COG1028@1|root,COG1028@2|Bacteria,2GAK3@200795|Chloroflexi,3774Y@32061|Chloroflexia	32061|Chloroflexia	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS1_k127_449340_4	1429046.RR21198_0466	3.003e-21	97.0	COG1950@1|root,COG1950@2|Bacteria,2IHP5@201174|Actinobacteria,4G28G@85025|Nocardiaceae	201174|Actinobacteria	S	Mycobacterial 4 TMS phage holin, superfamily IV	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
CMS1_k127_449340_0	56780.SYN_02631	6.012e-125	416.0	COG0668@1|root,COG0668@2|Bacteria,1N2GE@1224|Proteobacteria,42XYJ@68525|delta/epsilon subdivisions,2WSKT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Conserved TM helix repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TM_helix
CMS1_k127_4498856_5	251221.35214038	2.035e-05	53.0	COG5485@1|root,COG5485@2|Bacteria,1GEUM@1117|Cyanobacteria	1117|Cyanobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
CMS1_k127_4498856_3	1346791.M529_01070	1.982e-13	75.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,2U3G1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,CIA30
CMS1_k127_4498856_1	58344.JOEL01000016_gene5882	4.449e-55	205.0	COG1228@1|root,COG1228@2|Bacteria	2|Bacteria	Q	imidazolonepropionase activity	-	-	3.5.2.18	ko:K15358	ko00760,ko01120,map00760,map01120	-	R07984	RC01933	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
CMS1_k127_4498856_0	251229.Chro_3306	2.991e-290	942.0	COG1357@1|root,COG2319@1|root,COG3903@1|root,COG1357@2|Bacteria,COG2319@2|Bacteria,COG3903@2|Bacteria,1FZVW@1117|Cyanobacteria,3VJ0W@52604|Pleurocapsales	1117|Cyanobacteria	K	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC,Pentapeptide,WD40
CMS1_k127_4498856_2	754035.Mesau_02654	5.118e-36	160.0	COG2267@1|root,COG3629@1|root,COG2267@2|Bacteria,COG3629@2|Bacteria,1NIJG@1224|Proteobacteria,2U09P@28211|Alphaproteobacteria,43PM5@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	IT	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,BTAD,Hydrolase_4,Trans_reg_C
CMS1_k127_4498856_4	1123070.KB899248_gene210	3.905e-13	81.0	COG4974@1|root,COG4974@2|Bacteria,46SQ4@74201|Verrucomicrobia,2ITUM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Phage integrase, N-terminal SAM-like domain	-	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
CMS1_k127_4499397_8	485913.Krac_5027	6.797e-14	76.0	COG2909@1|root,COG3903@1|root,COG2909@2|Bacteria,COG3903@2|Bacteria,2G7SC@200795|Chloroflexi	200795|Chloroflexi	K	intracellular signal transduction	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12
CMS1_k127_4499397_7	926550.CLDAP_32540	1.378e-40	154.0	COG1765@1|root,COG1765@2|Bacteria,2G978@200795|Chloroflexi	200795|Chloroflexi	O	OsmC-like protein	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
CMS1_k127_4499397_3	485913.Krac_2662	2.949e-104	345.0	COG1028@1|root,COG1028@2|Bacteria,2G5R0@200795|Chloroflexi	200795|Chloroflexi	IQ	Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
CMS1_k127_4499397_6	1123373.ATXI01000002_gene637	1.899e-69	243.0	28IGY@1|root,2Z8I9@2|Bacteria,2GHAZ@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4499397_0	1123024.AUII01000035_gene1226	2.545e-138	455.0	COG1653@1|root,COG1653@2|Bacteria,2IDWS@201174|Actinobacteria,4E16T@85010|Pseudonocardiales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
CMS1_k127_4499397_1	1038859.AXAU01000018_gene6727	1.541e-134	437.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQQJ@28211|Alphaproteobacteria,3JQYC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
CMS1_k127_4499397_4	2074.JNYD01000004_gene4950	5.566e-98	330.0	COG1175@1|root,COG1175@2|Bacteria,2GJGB@201174|Actinobacteria,4DY7F@85010|Pseudonocardiales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_4499397_2	2074.JNYD01000004_gene4951	4.491e-105	349.0	COG0395@1|root,COG0395@2|Bacteria,2IDQB@201174|Actinobacteria	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
CMS1_k127_4499397_5	1382306.JNIM01000001_gene3378	8.596e-94	316.0	COG3342@1|root,COG3342@2|Bacteria,2G663@200795|Chloroflexi	200795|Chloroflexi	S	Family of unknown function (DUF1028)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1028,PG_binding_2
CMS1_k127_4500031_1	765420.OSCT_1822	1.683e-190	606.0	COG0747@1|root,COG0747@2|Bacteria,2G7R4@200795|Chloroflexi,37759@32061|Chloroflexia	32061|Chloroflexia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_4500031_3	765420.OSCT_1821	1.474e-95	322.0	COG0601@1|root,COG0601@2|Bacteria,2G6BV@200795|Chloroflexi,376PM@32061|Chloroflexia	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_4500031_2	765420.OSCT_1820	6.091e-99	333.0	COG1173@1|root,COG1173@2|Bacteria,2G6HB@200795|Chloroflexi,375I1@32061|Chloroflexia	32061|Chloroflexia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_4500031_0	42256.RradSPS_0358	5.188e-208	679.0	COG2909@1|root,COG2909@2|Bacteria,2HENR@201174|Actinobacteria,4CPC9@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,AAA_22,GerE
CMS1_k127_4500031_4	318424.EU78_21390	2.89e-30	124.0	COG1225@1|root,COG1225@2|Bacteria,2IC3G@201174|Actinobacteria,23DK4@1762|Mycobacteriaceae	201174|Actinobacteria	O	AhpC/TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS1_k127_4500031_5	263358.VAB18032_07210	4.933e-06	49.0	COG1225@1|root,COG1225@2|Bacteria,2H4Y3@201174|Actinobacteria,4DH21@85008|Micromonosporales	201174|Actinobacteria	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
CMS1_k127_4500483_3	1499967.BAYZ01000152_gene1407	4.256e-11	66.0	COG1177@1|root,COG1177@2|Bacteria	2|Bacteria	P	DNA import into cell involved in transformation	-	-	-	ko:K02053	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
CMS1_k127_4500483_2	1499967.BAYZ01000152_gene1408	1.807e-92	315.0	COG1176@1|root,COG1176@2|Bacteria	2|Bacteria	P	putrescine transport	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
CMS1_k127_4500483_0	1499967.BAYZ01000152_gene1409	2.768e-151	489.0	COG4134@1|root,COG4134@2|Bacteria	2|Bacteria	S	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
CMS1_k127_4500483_1	373994.Riv7116_5347	2.654e-104	347.0	COG3211@1|root,COG3211@2|Bacteria,1GIZZ@1117|Cyanobacteria,1HJZZ@1161|Nostocales	1117|Cyanobacteria	Q	Bacterial protein of unknown function (DUF839)	-	-	-	-	-	-	-	-	-	-	-	-	DUF839
CMS1_k127_4502456_15	428125.CLOLEP_00561	2.765e-05	55.0	COG3757@1|root,COG3807@1|root,COG3757@2|Bacteria,COG3807@2|Bacteria,1V2DN@1239|Firmicutes,25BKK@186801|Clostridia,3WS6V@541000|Ruminococcaceae	186801|Clostridia	M	Glycosyl hydrolases family 25	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_25
CMS1_k127_4502456_0	1128421.JAGA01000002_gene1647	7.209e-134	451.0	COG4412@1|root,COG4412@2|Bacteria,2NQMP@2323|unclassified Bacteria	2|Bacteria	E	Immune inhibitor A peptidase M6	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M6
CMS1_k127_4502456_9	634956.Geoth_0920	1.199e-43	161.0	COG0292@1|root,COG0292@2|Bacteria,1V6DB@1239|Firmicutes,4HH2W@91061|Bacilli,1WGH8@129337|Geobacillus	91061|Bacilli	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
CMS1_k127_4502456_14	243164.DET0751	5.743e-12	69.0	COG0291@1|root,COG0291@2|Bacteria,2G7D1@200795|Chloroflexi,34DG6@301297|Dehalococcoidia	301297|Dehalococcoidia	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
CMS1_k127_4502456_8	926569.ANT_02480	9.996e-53	193.0	COG0290@1|root,COG0290@2|Bacteria,2G6N2@200795|Chloroflexi	200795|Chloroflexi	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
CMS1_k127_4502456_1	926569.ANT_06740	6.282e-133	437.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	ko:K08217	-	-	-	-	br01600,ko00000,ko01504,ko02000	2.A.1.21.1,2.A.1.21.22	-	-	MFS_1
CMS1_k127_4502456_11	926550.CLDAP_09770	4.435e-31	125.0	COG3877@1|root,COG3877@2|Bacteria,2G734@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF2089)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2089
CMS1_k127_4502456_13	645991.Sgly_2723	3.776e-23	103.0	2CPG6@1|root,32SJ1@2|Bacteria,1VAYH@1239|Firmicutes,24N9N@186801|Clostridia,262FC@186807|Peptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4502456_10	765420.OSCT_0641	1.934e-43	167.0	COG4330@1|root,COG4330@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1361)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1361
CMS1_k127_4502456_12	1347369.CCAD010000092_gene2071	9.389e-26	110.0	COG1695@1|root,COG1695@2|Bacteria,1V4NA@1239|Firmicutes,4HHWW@91061|Bacilli,1ZINR@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator PadR-like family	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
CMS1_k127_4502456_4	479434.Sthe_1856	1.747e-102	340.0	COG0330@1|root,COG0330@2|Bacteria,2G5SB@200795|Chloroflexi,27XRQ@189775|Thermomicrobia	189775|Thermomicrobia	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
CMS1_k127_4502456_6	765698.Mesci_1648	2.112e-78	279.0	COG1653@1|root,COG1653@2|Bacteria,1N8AS@1224|Proteobacteria,2U19M@28211|Alphaproteobacteria,43P25@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	G	Extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
CMS1_k127_4502456_5	28444.JODQ01000012_gene3399	1.554e-81	283.0	COG1175@1|root,COG1175@2|Bacteria,2GM6N@201174|Actinobacteria,4EP4R@85012|Streptosporangiales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025,ko:K10228	ko02010,map02010	M00200,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.5	-	-	BPD_transp_1
CMS1_k127_4502456_7	1298858.AUEL01000026_gene3422	6.107e-77	269.0	COG0395@1|root,COG0395@2|Bacteria,1MVVT@1224|Proteobacteria,2TU85@28211|Alphaproteobacteria,43NBE@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	G	ABC-type sugar transport system, permease component	-	-	-	ko:K02026,ko:K10229	ko02010,map02010	M00200,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.5	-	-	BPD_transp_1
CMS1_k127_4502456_3	935866.JAER01000012_gene3471	1.238e-110	370.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the ABC transporter superfamily	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
CMS1_k127_4502456_2	368408.Tpen_1165	7.018e-112	372.0	COG3839@1|root,arCOG00175@2157|Archaea,2XPUC@28889|Crenarchaeota	28889|Crenarchaeota	G	PFAM ABC transporter related	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
CMS1_k127_4508409_12	1217720.ALOX01000078_gene3178	4.175e-10	64.0	COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,2TRUK@28211|Alphaproteobacteria,2JPUE@204441|Rhodospirillales	204441|Rhodospirillales	E	Belongs to the peptidase M20A family. ArgE subfamily	-	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
CMS1_k127_4508409_11	869210.Marky_0902	3.761e-26	124.0	COG1621@1|root,COG1621@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 32 family	-	-	3.2.1.26	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R00802,R02410,R03635,R03921,R06088	RC00028,RC00077	ko00000,ko00001,ko01000	-	GH32	-	Glyco_hydro_32N
CMS1_k127_4508409_0	649638.Trad_2292	7.197e-258	804.0	COG2407@1|root,COG2407@2|Bacteria,1WKXP@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Converts the aldose L-fucose into the corresponding ketose L-fuculose	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4508409_2	521098.Aaci_2899	1.826e-204	651.0	COG1069@1|root,COG1069@2|Bacteria,1TP8T@1239|Firmicutes,4HC3A@91061|Bacilli	91061|Bacilli	C	Belongs to the ribulokinase family	araB	-	2.7.1.16	ko:K00853	ko00040,ko01100,map00040,map01100	-	R01526,R02439	RC00002,RC00538	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
CMS1_k127_4508409_4	926550.CLDAP_12710	1.125e-104	347.0	COG3347@1|root,COG3347@2|Bacteria	2|Bacteria	IQ	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
CMS1_k127_4508409_8	97139.C824_01928	1.83e-78	274.0	COG0673@1|root,COG0673@2|Bacteria,1TP83@1239|Firmicutes,248XQ@186801|Clostridia,36F4R@31979|Clostridiaceae	186801|Clostridia	S	Oxidoreductase family, C-terminal alpha beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_4508409_13	1280946.HY29_08475	3.816e-05	53.0	COG1905@1|root,COG3743@1|root,COG1905@2|Bacteria,COG3743@2|Bacteria,1MWS2@1224|Proteobacteria,2TSEJ@28211|Alphaproteobacteria,43W6C@69657|Hyphomonadaceae	28211|Alphaproteobacteria	C	COG1905 NADH ubiquinone oxidoreductase 24 kD subunit	nuoE	-	1.6.5.3,1.6.99.3	ko:K00334,ko:K03943	ko00190,ko01100,ko04714,ko04723,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04714,map04723,map04932,map05010,map05012,map05016	M00143,M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1,3.D.1.6	-	-	2Fe-2S_thioredx
CMS1_k127_4508409_1	1122138.AQUZ01000014_gene6984	1.838e-252	807.0	COG4354@1|root,COG4354@2|Bacteria,2I9UI@201174|Actinobacteria,4DTFP@85009|Propionibacteriales	201174|Actinobacteria	G	beta-glucosidase 2, glycosyl-hydrolase family 116 N-term	-	-	-	-	-	-	-	-	-	-	-	-	DUF608,Glyco_hydr_116N
CMS1_k127_4508409_7	697281.Mahau_0032	4.058e-94	321.0	COG0407@1|root,COG0407@2|Bacteria,1V5KX@1239|Firmicutes,24IAR@186801|Clostridia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
CMS1_k127_4508409_6	428125.CLOLEP_02139	7.497e-98	327.0	COG0395@1|root,COG0395@2|Bacteria,1TRCP@1239|Firmicutes,249NY@186801|Clostridia,3WHKY@541000|Ruminococcaceae	186801|Clostridia	P	ABC-type sugar transport system, permease component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_4508409_5	428125.CLOLEP_02138	3.095e-98	331.0	COG1175@1|root,COG1175@2|Bacteria,1TREE@1239|Firmicutes,249MK@186801|Clostridia,3WRTG@541000|Ruminococcaceae	186801|Clostridia	P	COG COG1175 ABC-type sugar transport systems, permease components	-	-	-	ko:K02025,ko:K17242	ko02010,map02010	M00207,M00600	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.39	-	-	BPD_transp_1
CMS1_k127_4508409_3	1041159.AZUW01000033_gene2487	7.076e-130	428.0	COG1653@1|root,COG1653@2|Bacteria,1R4ZH@1224|Proteobacteria,2VGH8@28211|Alphaproteobacteria,4BD2X@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027,ko:K10117	ko02010,map02010	M00196,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.28	-	-	SBP_bac_8
CMS1_k127_4508409_9	525904.Tter_2210	4.222e-78	273.0	COG1609@1|root,COG1609@2|Bacteria,2NR26@2323|unclassified Bacteria	2|Bacteria	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
CMS1_k127_4508409_10	479434.Sthe_2433	3.38e-48	174.0	COG0277@1|root,COG0277@2|Bacteria,2G7TD@200795|Chloroflexi	200795|Chloroflexi	C	D-arabinono-1,4-lactone oxidase	-	-	-	-	-	-	-	-	-	-	-	-	ALO,FAD_binding_4
CMS1_k127_4509284_7	926564.KI911664_gene850	6.97e-09	68.0	COG1653@1|root,COG1653@2|Bacteria,2GJIP@201174|Actinobacteria	201174|Actinobacteria	G	Extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
CMS1_k127_4509284_4	1274374.CBLK010000070_gene1201	3.624e-44	174.0	COG1175@1|root,COG1175@2|Bacteria,1TRC0@1239|Firmicutes,4HGQR@91061|Bacilli,26T06@186822|Paenibacillaceae	91061|Bacilli	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025,ko:K05814	ko02010,map02010	M00198,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.3	-	-	BPD_transp_1
CMS1_k127_4509284_5	1463857.JOFZ01000011_gene2094	4.814e-41	162.0	COG0395@1|root,COG0395@2|Bacteria,2GMTH@201174|Actinobacteria	201174|Actinobacteria	G	ABC transporter (Permease)	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_4509284_2	247490.KSU1_C0907	1.879e-101	344.0	COG0644@1|root,COG0644@2|Bacteria,2J1WS@203682|Planctomycetes	203682|Planctomycetes	C	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4509284_3	237368.SCABRO_02137	2.674e-64	241.0	COG0644@1|root,COG0644@2|Bacteria	2|Bacteria	C	geranylgeranyl reductase activity	prnA	-	1.14.19.9	ko:K14266	ko00404,ko01130,map00404,map01130	M00789,M00790	R09570	RC00949	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_halogenase
CMS1_k127_4509284_6	1540257.JQMW01000004_gene368	2.233e-22	104.0	29UV3@1|root,316MX@2|Bacteria,1UH1R@1239|Firmicutes,24QZD@186801|Clostridia,36VDG@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3
CMS1_k127_4509284_0	1501230.ET33_37205	3.828e-178	575.0	COG1132@1|root,COG1132@2|Bacteria,1TRCZ@1239|Firmicutes,4HCDT@91061|Bacilli,26RQU@186822|Paenibacillaceae	91061|Bacilli	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
CMS1_k127_4509284_1	292459.STH1427	4.504e-154	508.0	COG1132@1|root,COG1132@2|Bacteria,1UZA0@1239|Firmicutes,24DXZ@186801|Clostridia	186801|Clostridia	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS1_k127_4511487_0	556261.HMPREF0240_03852	4.726e-135	440.0	COG0407@1|root,COG0407@2|Bacteria,1UY51@1239|Firmicutes,24DZF@186801|Clostridia,36QW9@31979|Clostridiaceae	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
CMS1_k127_4511487_2	765420.OSCT_3186	1.311e-10	66.0	COG4995@1|root,COG4995@2|Bacteria,2G8YF@200795|Chloroflexi,377C0@32061|Chloroflexia	32061|Chloroflexia	P	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,SIR2_2
CMS1_k127_4511487_1	745718.JADT01000011_gene752	1.396e-29	138.0	COG0739@1|root,COG0739@2|Bacteria,4NMHB@976|Bacteroidetes,1I1UE@117743|Flavobacteriia	976|Bacteroidetes	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CMS1_k127_4511487_3	85681.XP_006444660.1	7.162e-10	73.0	COG3934@1|root,2QS4Q@2759|Eukaryota,37PFM@33090|Viridiplantae,3GCR2@35493|Streptophyta	35493|Streptophyta	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0004567,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010412,GO:0015923,GO:0016052,GO:0016787,GO:0016798,GO:0016985,GO:0016998,GO:0043170,GO:0044036,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0046355,GO:0071554,GO:0071704,GO:1901575	3.2.1.78	ko:K19355	ko00051,map00051	-	R01332	RC00467	ko00000,ko00001,ko01000	-	-	-	Cellulase
CMS1_k127_4520484_5	1158050.KB895461_gene2928	1.367e-27	124.0	COG0125@1|root,COG3173@1|root,COG0125@2|Bacteria,COG3173@2|Bacteria,2H78H@201174|Actinobacteria	201174|Actinobacteria	F	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4520484_2	316274.Haur_0194	1.124e-60	231.0	COG0489@1|root,COG3206@1|root,COG3944@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,COG3944@2|Bacteria,2G5WM@200795|Chloroflexi,376C8@32061|Chloroflexia	32061|Chloroflexia	M	PFAM lipopolysaccharide biosynthesis protein	-	-	2.7.10.2	ko:K08253	-	-	-	-	ko00000,ko01000	-	-	-	CbiA,Wzz
CMS1_k127_4520484_10	1196028.ALEF01000043_gene496	9.894e-05	49.0	COG1396@1|root,COG1396@2|Bacteria,1VGZQ@1239|Firmicutes	1239|Firmicutes	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
CMS1_k127_4520484_1	316274.Haur_5252	3.751e-89	316.0	COG2801@1|root,COG2801@2|Bacteria,2G8JR@200795|Chloroflexi	200795|Chloroflexi	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	rve
CMS1_k127_4520484_3	493475.GARC_0477	6.08e-39	156.0	COG2819@1|root,COG2819@2|Bacteria,1R54Q@1224|Proteobacteria,1SAFU@1236|Gammaproteobacteria,468T4@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Putative esterase	-	-	-	ko:K07017	-	-	-	-	ko00000	-	-	-	Esterase
CMS1_k127_4520484_0	1396141.BATP01000044_gene1481	7.087e-119	395.0	COG4941@1|root,COG4941@2|Bacteria,46SEY@74201|Verrucomicrobia,2IV8H@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
CMS1_k127_4520484_6	1121904.ARBP01000026_gene656	2.746e-27	115.0	COG3795@1|root,COG3795@2|Bacteria,4NS2I@976|Bacteroidetes,47RFW@768503|Cytophagia	976|Bacteroidetes	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
CMS1_k127_4520484_7	743722.Sph21_2582	9.675e-27	115.0	COG3832@1|root,COG3832@2|Bacteria,4NNTR@976|Bacteroidetes,1IQR8@117747|Sphingobacteriia	976|Bacteroidetes	S	Pfam Activator of Hsp90 ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
CMS1_k127_4520484_8	926550.CLDAP_34220	1.41e-26	110.0	COG1278@1|root,COG1278@2|Bacteria,2G7EU@200795|Chloroflexi	200795|Chloroflexi	K	'Cold-shock' DNA-binding domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
CMS1_k127_4520484_9	1246448.ANAZ01000048_gene3280	7.482e-07	53.0	COG2267@1|root,COG2267@2|Bacteria,2GJUE@201174|Actinobacteria	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
CMS1_k127_4520484_4	1463909.KL585966_gene449	4.215e-38	148.0	COG3576@1|root,COG3576@2|Bacteria	2|Bacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
CMS1_k127_4523552_2	118166.JH976537_gene1110	4.275e-66	229.0	COG1171@1|root,COG1171@2|Bacteria,1GC6F@1117|Cyanobacteria,1HE54@1150|Oscillatoriales	1117|Cyanobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	PALP
CMS1_k127_4523552_0	240016.ABIZ01000001_gene2223	1.305e-120	400.0	COG0624@1|root,COG0624@2|Bacteria,46VZE@74201|Verrucomicrobia,2IW3Z@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
CMS1_k127_4523552_3	449447.MAE_59050	1.685e-11	70.0	COG1366@1|root,COG1366@2|Bacteria,1G7NW@1117|Cyanobacteria	1117|Cyanobacteria	T	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	-	-	-	-	-	-	-	-	-	-	-	-	STAS
CMS1_k127_4523552_1	926550.CLDAP_19010	2.657e-87	291.0	COG2818@1|root,COG2818@2|Bacteria,2G78E@200795|Chloroflexi	200795|Chloroflexi	L	Methyladenine glycosylase	-	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
CMS1_k127_4528058_2	196367.JNFG01000003_gene5636	6.503e-78	270.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,2W0B8@28216|Betaproteobacteria,1K0YP@119060|Burkholderiaceae	28216|Betaproteobacteria	C	C-terminal domain of alpha-glycerophosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	DAO,DAO_C
CMS1_k127_4528058_0	378806.STAUR_3903	1.127e-274	852.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,42M1X@68525|delta/epsilon subdivisions,2WJA2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	TIGRFAM acetolactate synthase, large subunit, biosynthetic type	-	-	2.2.1.6,2.3.3.15	ko:K01652,ko:K03852	ko00290,ko00430,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00430,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R05651,R08648	RC00027,RC00106,RC01192,RC02744,RC02893,RC02903,RC02909	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS1_k127_4528058_1	1122221.JHVI01000016_gene1617	9.123e-145	467.0	COG0479@1|root,COG0479@2|Bacteria	2|Bacteria	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	asrA	-	-	ko:K16950	ko00920,ko01120,map00920,map01120	-	R00858,R10146	RC00065	ko00000,ko00001	-	-	-	Fer4_22
CMS1_k127_4528058_3	344747.PM8797T_02809	2.898e-42	161.0	COG0543@1|root,COG0543@2|Bacteria,2IYBB@203682|Planctomycetes	203682|Planctomycetes	C	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B	-	-	-	-	-	-	-	-	-	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
CMS1_k127_4528253_0	1125863.JAFN01000001_gene1552	0.0	1684.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,1QUM4@1224|Proteobacteria,42MPP@68525|delta/epsilon subdivisions,2WJ3U@28221|Deltaproteobacteria	2|Bacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,Fer4_4,Fer4_7,NAD_binding_8,Pyr_redox_2
CMS1_k127_4528253_12	768706.Desor_4438	1.082e-50	183.0	COG1908@1|root,COG1908@2|Bacteria,1V638@1239|Firmicutes,24J0E@186801|Clostridia,261V3@186807|Peptococcaceae	186801|Clostridia	C	PFAM methyl-viologen-reducing hydrogenase delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	FlpD
CMS1_k127_4528253_1	1121472.AQWN01000006_gene1827	1.619e-280	899.0	COG1148@1|root,COG1249@1|root,COG1148@2|Bacteria,COG1249@2|Bacteria,1V5YJ@1239|Firmicutes,248CC@186801|Clostridia,2641A@186807|Peptococcaceae	186801|Clostridia	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Pyr_redox_2
CMS1_k127_4528253_13	926569.ANT_29820	3.484e-43	166.0	COG0517@1|root,COG0517@2|Bacteria,2G6TI@200795|Chloroflexi	200795|Chloroflexi	S	amino acid-binding ACT domain protein	-	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	CBS
CMS1_k127_4528253_10	1122947.FR7_3972	2.767e-63	228.0	COG3634@1|root,COG3634@2|Bacteria,1TPYN@1239|Firmicutes,4H46S@909932|Negativicutes	909932|Negativicutes	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	-	-	-	ko:K03387	-	-	-	-	ko00000,ko01000	-	-	-	Pyr_redox_2
CMS1_k127_4528253_4	1480694.DC28_13880	7.203e-205	645.0	COG0281@1|root,COG0281@2|Bacteria,2J5DN@203691|Spirochaetes	203691|Spirochaetes	C	Malic enzyme, NAD binding domain	mdh	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,malic
CMS1_k127_4528253_11	555779.Dthio_PD3223	1.634e-60	220.0	COG1410@1|root,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,42Q13@68525|delta/epsilon subdivisions,2WIT3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM dihydropteroate synthase, DHPS	-	-	2.1.1.258	ko:K15023	ko00720,ko01120,ko01200,map00720,map01120,map01200	M00377	R02289,R10243	RC00004,RC00113,RC01144,RC02871,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
CMS1_k127_4528253_9	1121472.AQWN01000006_gene1841	1.606e-65	233.0	COG3640@1|root,COG3640@2|Bacteria,1UZHR@1239|Firmicutes,24BYR@186801|Clostridia,260D8@186807|Peptococcaceae	186801|Clostridia	D	PFAM CobQ CobB MinD ParA nucleotide binding domain	cooC1	-	-	ko:K07321	-	-	-	-	ko00000	-	-	-	CbiA
CMS1_k127_4528253_7	485916.Dtox_1611	4.977e-103	343.0	COG0535@1|root,COG0535@2|Bacteria,1URM8@1239|Firmicutes,24XB8@186801|Clostridia	186801|Clostridia	C	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
CMS1_k127_4528253_5	429009.Adeg_0338	1.945e-148	494.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,1TP0H@1239|Firmicutes,247S0@186801|Clostridia,42F3G@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
CMS1_k127_4528253_6	429009.Adeg_0337	3.661e-119	397.0	COG1456@1|root,COG1456@2|Bacteria,1TPWJ@1239|Firmicutes,24CTU@186801|Clostridia,42EP5@68295|Thermoanaerobacterales	186801|Clostridia	C	CO dehydrogenase/acetyl-CoA synthase delta subunit	acsC	-	2.1.1.245	ko:K00197	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00357,M00377,M00422	R09096,R10219,R10243	RC00004,RC00113,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhD,FeS
CMS1_k127_4528253_8	574087.Acear_1300	4.826e-95	322.0	COG2069@1|root,COG2069@2|Bacteria,1TSSY@1239|Firmicutes,24BVJ@186801|Clostridia	186801|Clostridia	C	CO dehydrogenase acetyl-CoA synthase delta subunit	acsD	-	2.1.1.245	ko:K00194	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00357,M00377,M00422	R09096,R10219,R10243	RC00004,RC00113,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhD
CMS1_k127_4528253_15	439235.Dalk_0950	5.824e-25	106.0	COG3360@1|root,COG3360@2|Bacteria,1Q2I5@1224|Proteobacteria,42VRR@68525|delta/epsilon subdivisions,2WRD2@28221|Deltaproteobacteria,2MM5C@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
CMS1_k127_4528253_17	1521187.JPIM01000032_gene1978	1.929e-09	64.0	COG2905@1|root,COG2905@2|Bacteria,2G9RT@200795|Chloroflexi,375Z7@32061|Chloroflexia	32061|Chloroflexia	T	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
CMS1_k127_4528253_2	555779.Dthio_PD3239	1.5e-277	874.0	COG1614@1|root,COG1614@2|Bacteria,1MVI5@1224|Proteobacteria,42N9A@68525|delta/epsilon subdivisions,2WK4H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit	-	-	2.3.1.169	ko:K14138	ko00720,ko01120,ko01200,map00720,map01120,map01200	M00377	R08433,R10243	RC00004,RC00113,RC01144,RC02963,RC02964,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhC
CMS1_k127_4528253_3	909663.KI867150_gene97	6.179e-222	706.0	COG0369@1|root,COG1151@2|Bacteria,1NYH2@1224|Proteobacteria,42NE1@68525|delta/epsilon subdivisions,2WIVX@28221|Deltaproteobacteria,2MQ8Q@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit	-	-	1.2.7.4	ko:K00198	ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200	M00377	R07157,R08034	RC00250,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Prismane
CMS1_k127_4528253_16	1048339.KB913029_gene1432	6.641e-10	68.0	COG2452@1|root,COG2452@2|Bacteria,2GQJ9@201174|Actinobacteria,4ETDG@85013|Frankiales	201174|Actinobacteria	L	TIGRFAM DNA binding domain	bldC	-	-	-	-	-	-	-	-	-	-	-	HTH_17
CMS1_k127_4528253_14	243164.DET0185	3.13e-32	135.0	COG3058@1|root,COG3058@2|Bacteria,2G9S5@200795|Chloroflexi,34CZK@301297|Dehalococcoidia	301297|Dehalococcoidia	O	Necessary for formate dehydrogenase activity	-	-	-	ko:K02380	-	-	-	-	ko00000	-	-	-	FdhE
CMS1_k127_4529322_0	1500281.JQKZ01000004_gene3588	3.55e-67	243.0	COG1680@1|root,COG1680@2|Bacteria,4NGKK@976|Bacteroidetes,1HX0I@117743|Flavobacteriia,3ZSG5@59732|Chryseobacterium	976|Bacteroidetes	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS1_k127_4529322_2	324602.Caur_3143	2.222e-26	119.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
CMS1_k127_4529322_1	1380384.JADN01000007_gene1608	4.621e-34	148.0	COG1228@1|root,COG1228@2|Bacteria,4NEV0@976|Bacteroidetes,1HZW4@117743|Flavobacteriia	976|Bacteroidetes	Q	COG1228 Imidazolonepropionase and related	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
CMS1_k127_4533047_1	1382304.JNIL01000001_gene1212	2.432e-114	384.0	COG0165@1|root,COG0165@2|Bacteria,1U4V0@1239|Firmicutes,4HE7Q@91061|Bacilli,27ARF@186823|Alicyclobacillaceae	91061|Bacilli	E	Argininosuccinate lyase C-terminal	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
CMS1_k127_4533047_2	1122223.KB890697_gene1219	1.59e-105	350.0	COG0395@1|root,COG0395@2|Bacteria,1WIW4@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_4533047_3	526227.Mesil_2465	6.781e-96	323.0	COG1175@1|root,COG1175@2|Bacteria,1WJ21@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_4533047_0	1380394.JADL01000005_gene5693	1.338e-123	410.0	COG1653@1|root,COG1653@2|Bacteria,1MVMW@1224|Proteobacteria,2TTMX@28211|Alphaproteobacteria,2JR91@204441|Rhodospirillales	204441|Rhodospirillales	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4533047_4	416591.Tlet_1114	2.469e-84	285.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
CMS1_k127_4533655_2	926569.ANT_27010	3.745e-43	161.0	COG0071@1|root,COG0071@2|Bacteria,2G71M@200795|Chloroflexi	200795|Chloroflexi	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
CMS1_k127_4533655_0	1463857.JOFZ01000015_gene938	5.939e-157	501.0	COG1082@1|root,COG1082@2|Bacteria,2GK1S@201174|Actinobacteria	201174|Actinobacteria	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
CMS1_k127_4533655_1	937777.Deipe_3129	5.484e-72	248.0	COG0673@1|root,COG0673@2|Bacteria,1WM59@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_4534159_2	1303518.CCALI_01047	7.638e-58	210.0	COG1801@1|root,COG1801@2|Bacteria	2|Bacteria	L	Protein of unknown function DUF72	yecE	-	-	-	-	-	-	-	-	-	-	-	DUF72
CMS1_k127_4534159_0	869210.Marky_1959	3.759e-110	364.0	COG0109@1|root,COG1612@1|root,COG0109@2|Bacteria,COG1612@2|Bacteria,1WIAB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	COX15-CtaA,UbiA
CMS1_k127_4534159_1	485913.Krac_10314	1.261e-67	243.0	COG1718@1|root,COG1718@2|Bacteria	2|Bacteria	DT	cellular response to dsDNA	IV02_22125	-	2.7.11.1	ko:K07178	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko01001,ko03009	-	-	-	RIO1
CMS1_k127_4537103_9	926550.CLDAP_16150	3.136e-08	59.0	COG2128@1|root,COG2128@2|Bacteria	2|Bacteria	S	hydroperoxide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD,DUF3179
CMS1_k127_4537103_2	926550.CLDAP_37690	3.766e-76	259.0	COG1898@1|root,COG1898@2|Bacteria,2G7AS@200795|Chloroflexi	200795|Chloroflexi	M	dTDP-4-dehydrorhamnose 3,5-epimerase	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
CMS1_k127_4537103_8	383372.Rcas_3831	2.243e-08	65.0	COG0457@1|root,COG0457@2|Bacteria,2G9Z0@200795|Chloroflexi,377FD@32061|Chloroflexia	32061|Chloroflexia	NU	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4537103_6	926550.CLDAP_23410	2.686e-40	153.0	2FJCP@1|root,34B2I@2|Bacteria,2G94J@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4537103_1	926550.CLDAP_23400	7.131e-93	325.0	2EYH8@1|root,33RR4@2|Bacteria,2G7WE@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4537103_7	926569.ANT_30300	4.2e-32	132.0	2FH2K@1|root,348XD@2|Bacteria,2G93E@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4537103_0	269800.Tfu_1753	1.47e-242	769.0	COG0507@1|root,COG0507@2|Bacteria,2GJRK@201174|Actinobacteria,4EHE2@85012|Streptosporangiales	201174|Actinobacteria	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
CMS1_k127_4537103_4	926550.CLDAP_05580	2.521e-58	213.0	COG1608@1|root,COG1608@2|Bacteria,2G6TH@200795|Chloroflexi	200795|Chloroflexi	S	PFAM aspartate glutamate uridylate kinase	-	-	2.7.4.26	ko:K06981	ko00900,ko01110,ko01130,map00900,map01110,map01130	-	R10093	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
CMS1_k127_4537103_5	1499967.BAYZ01000073_gene2016	1.396e-54	198.0	COG1739@1|root,COG1739@2|Bacteria,2NPZP@2323|unclassified Bacteria	2|Bacteria	S	Uncharacterized protein family UPF0029	yigZ	-	2.1.1.45,3.4.13.9	ko:K00560,ko:K01271	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	DUF1949,UPF0029
CMS1_k127_4537103_3	1487953.JMKF01000020_gene2252	2.153e-67	241.0	COG3173@1|root,COG3173@2|Bacteria	2|Bacteria	S	very-long-chain-acyl-CoA dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS1_k127_4538775_0	395961.Cyan7425_1965	9.448e-131	423.0	COG0174@1|root,COG0174@2|Bacteria	2|Bacteria	E	glutamine synthetase	glnA2	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C
CMS1_k127_4538775_2	395961.Cyan7425_1964	5.97e-62	221.0	COG2071@1|root,COG2071@2|Bacteria,1G5CB@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Peptidase C26	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
CMS1_k127_4538775_1	671143.DAMO_1998	1.028e-66	256.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	DUF3367,DUF5122
CMS1_k127_4538775_3	1089547.KB913014_gene4920	3.81e-29	136.0	COG3210@1|root,COG3210@2|Bacteria,4NTNN@976|Bacteroidetes,47K8B@768503|Cytophagia	976|Bacteroidetes	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Chlam_PMP,SprB
CMS1_k127_4539959_2	1131462.DCF50_p756	1.039e-54	198.0	COG0596@1|root,COG0596@2|Bacteria,1V0M4@1239|Firmicutes,24AEI@186801|Clostridia,262HK@186807|Peptococcaceae	186801|Clostridia	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CMS1_k127_4539959_4	1268072.PSAB_10230	1.019e-21	102.0	COG2074@1|root,COG2074@2|Bacteria,1UJSS@1239|Firmicutes,4HQUT@91061|Bacilli,272FT@186822|Paenibacillaceae	91061|Bacilli	G	phosphotransferase activity, carboxyl group as acceptor	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4539959_1	1089551.KE386572_gene2233	1.137e-99	332.0	COG0500@1|root,COG2226@2|Bacteria,1PPKI@1224|Proteobacteria,2TRIB@28211|Alphaproteobacteria,4BSGF@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
CMS1_k127_4539959_5	1501230.ET33_02970	2.066e-12	81.0	COG2909@1|root,COG2909@2|Bacteria,1UIMV@1239|Firmicutes,4HD7H@91061|Bacilli,26QDM@186822|Paenibacillaceae	91061|Bacilli	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
CMS1_k127_4539959_0	926560.KE387023_gene3263	4.836e-120	417.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,1WM5I@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12
CMS1_k127_4539959_3	1173024.KI912149_gene5629	1.329e-52	193.0	COG1309@1|root,COG1309@2|Bacteria,1G5HM@1117|Cyanobacteria,1JI00@1189|Stigonemataceae	1117|Cyanobacteria	K	Bacterial transcriptional repressor C-terminal	-	-	-	ko:K16137	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_11,TetR_C_13,TetR_C_6,TetR_N
CMS1_k127_4544520_0	479434.Sthe_1742	1.115e-161	515.0	COG4447@1|root,COG4447@2|Bacteria,2G678@200795|Chloroflexi,27YSS@189775|Thermomicrobia	189775|Thermomicrobia	S	PFAM glycosyl hydrolase BNR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CMS1_k127_4544520_3	485915.Dret_0274	1.708e-34	145.0	COG0701@1|root,COG0701@2|Bacteria,1NC9P@1224|Proteobacteria,42UV0@68525|delta/epsilon subdivisions,2WNWM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Predicted permease	-	-	-	-	-	-	-	-	-	-	-	-	ArsP_1,Nitro_FeMo-Co
CMS1_k127_4544520_2	485915.Dret_0275	9.692e-45	168.0	COG0701@1|root,COG0701@2|Bacteria	2|Bacteria	S	Predicted permease	MA20_06590	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
CMS1_k127_4544520_1	357808.RoseRS_1433	3.249e-112	372.0	COG0010@1|root,COG0010@2|Bacteria,2G8DY@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the arginase family	-	-	3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
CMS1_k127_4545243_5	926550.CLDAP_35990	1.688e-63	225.0	2F1C8@1|root,33UD3@2|Bacteria,2G8D9@200795|Chloroflexi	200795|Chloroflexi	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
CMS1_k127_4545243_4	926550.CLDAP_31570	1.49e-168	535.0	COG0673@1|root,COG0673@2|Bacteria,2G6KB@200795|Chloroflexi	200795|Chloroflexi	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_4545243_1	1265505.ATUG01000002_gene1633	2.402e-232	727.0	COG3033@1|root,COG3033@2|Bacteria,1NG5U@1224|Proteobacteria,42QJ3@68525|delta/epsilon subdivisions,2WKUT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Beta-eliminating lyase	-	-	4.1.99.1	ko:K01667	ko00380,map00380	-	R00673	RC00209,RC00355	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
CMS1_k127_4545243_2	357808.RoseRS_2871	6.649e-211	685.0	COG0744@1|root,COG0744@2|Bacteria,2G5ZG@200795|Chloroflexi,376FV@32061|Chloroflexia	32061|Chloroflexia	M	Penicillin-Binding Protein C-terminus Family	-	-	-	-	-	-	-	-	-	-	-	-	BiPBP_C,Transgly,Transpeptidase
CMS1_k127_4545243_3	1499967.BAYZ01000050_gene2808	1.652e-175	554.0	COG1087@1|root,COG1087@2|Bacteria,2NNVI@2323|unclassified Bacteria	2|Bacteria	M	NAD(P)H-binding	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
CMS1_k127_4545243_6	1499967.BAYZ01000105_gene3517	2.225e-21	108.0	COG2755@1|root,COG2755@2|Bacteria,2NR42@2323|unclassified Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	ChitinaseA_N,Lipase_GDSL_2
CMS1_k127_4545243_0	926550.CLDAP_29090	0.0	1235.0	COG2373@1|root,COG2373@2|Bacteria,2G5XN@200795|Chloroflexi	200795|Chloroflexi	S	PFAM alpha-2-macroglobulin domain protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,Big_5,MG1
CMS1_k127_4554312_3	1227453.C444_08765	6.49e-25	117.0	COG4748@1|root,arCOG04669@2157|Archaea	2157|Archaea	V	Type I restriction enzyme R protein N terminus (HSDR_N)	-	-	-	ko:K07504	-	-	-	-	ko00000	-	-	-	HSDR_N_2
CMS1_k127_4554312_2	383372.Rcas_4057	2.587e-30	123.0	COG2127@1|root,COG2127@2|Bacteria,2G9F8@200795|Chloroflexi,375WT@32061|Chloroflexia	32061|Chloroflexia	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
CMS1_k127_4554312_1	383372.Rcas_0802	1.181e-32	136.0	COG1719@1|root,COG1719@2|Bacteria,2G8D0@200795|Chloroflexi,375HS@32061|Chloroflexia	32061|Chloroflexia	S	4-vinyl reductase, 4VR	-	-	-	-	-	-	-	-	-	-	-	-	V4R
CMS1_k127_4554312_0	357808.RoseRS_3212	3.028e-106	352.0	COG0664@1|root,COG1136@1|root,COG0664@2|Bacteria,COG1136@2|Bacteria,2G6C9@200795|Chloroflexi,37685@32061|Chloroflexia	32061|Chloroflexia	V	ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,cNMP_binding
CMS1_k127_4555325_1	926569.ANT_13030	2.637e-77	263.0	COG0174@1|root,COG0174@2|Bacteria,2G61M@200795|Chloroflexi	200795|Chloroflexi	E	PFAM glutamine synthetase catalytic region	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
CMS1_k127_4555325_0	357808.RoseRS_0076	5.221e-167	542.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,2G5K6@200795|Chloroflexi,376BY@32061|Chloroflexia	32061|Chloroflexia	L	Helix-hairpin-helix DNA-binding, class 1	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_thumb,HHH_5,HHH_8,PHP
CMS1_k127_4555325_3	1034769.KB910518_gene2779	9.346e-22	100.0	COG0745@1|root,COG0745@2|Bacteria,1TSWT@1239|Firmicutes,4HGB5@91061|Bacilli,26RSX@186822|Paenibacillaceae	91061|Bacilli	T	Heme response regulator HssR	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_4555325_2	765420.OSCT_0593	3.467e-64	235.0	COG0664@1|root,COG2208@1|root,COG0664@2|Bacteria,COG2208@2|Bacteria,2G790@200795|Chloroflexi	200795|Chloroflexi	T	Stage II sporulation E family protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,SpoIIE,cNMP_binding
CMS1_k127_4555325_5	383372.Rcas_2165	0.0003135	50.0	2C4GS@1|root,2ZTIR@2|Bacteria,2GBQH@200795|Chloroflexi,3761W@32061|Chloroflexia	32061|Chloroflexia	S	Bacterial SH3 domain	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
CMS1_k127_4555325_4	7897.ENSLACP00000009742	8.253e-12	65.0	COG1960@1|root,KOG0140@2759|Eukaryota,38BNR@33154|Opisthokonta,3BCJM@33208|Metazoa,3CV7W@33213|Bilateria,484GK@7711|Chordata,4905F@7742|Vertebrata	33208|Metazoa	I	acyl-CoA dehydrogenase	ACADM	GO:0000062,GO:0000166,GO:0000271,GO:0001889,GO:0003674,GO:0003824,GO:0003995,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005740,GO:0005759,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006082,GO:0006091,GO:0006109,GO:0006111,GO:0006112,GO:0006575,GO:0006577,GO:0006578,GO:0006629,GO:0006631,GO:0006635,GO:0006807,GO:0006950,GO:0007275,GO:0007507,GO:0007584,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009059,GO:0009062,GO:0009250,GO:0009266,GO:0009409,GO:0009437,GO:0009605,GO:0009628,GO:0009719,GO:0009725,GO:0009791,GO:0009888,GO:0009889,GO:0009987,GO:0009991,GO:0010033,GO:0010035,GO:0010038,GO:0010675,GO:0010906,GO:0014070,GO:0014706,GO:0015980,GO:0016020,GO:0016042,GO:0016043,GO:0016051,GO:0016054,GO:0016491,GO:0016604,GO:0016607,GO:0016627,GO:0016853,GO:0017076,GO:0019216,GO:0019222,GO:0019254,GO:0019395,GO:0019752,GO:0022607,GO:0030154,GO:0030258,GO:0030424,GO:0030554,GO:0031090,GO:0031323,GO:0031667,GO:0031960,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033218,GO:0033539,GO:0033692,GO:0033993,GO:0034440,GO:0034637,GO:0034641,GO:0034645,GO:0035051,GO:0036094,GO:0042221,GO:0042398,GO:0042493,GO:0042594,GO:0042692,GO:0042802,GO:0042995,GO:0043005,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043255,GO:0043436,GO:0043933,GO:0044042,GO:0044085,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0045329,GO:0046395,GO:0046688,GO:0048037,GO:0048513,GO:0048545,GO:0048731,GO:0048732,GO:0048738,GO:0048856,GO:0048869,GO:0050660,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051146,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051384,GO:0051791,GO:0051793,GO:0055007,GO:0055114,GO:0060537,GO:0061008,GO:0061061,GO:0062012,GO:0065003,GO:0065007,GO:0070013,GO:0070991,GO:0071704,GO:0071840,GO:0072329,GO:0072359,GO:0080090,GO:0097159,GO:0097164,GO:0097367,GO:0097458,GO:0120025,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901567,GO:1901575,GO:1901576,GO:1901681	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS1_k127_4557161_2	926550.CLDAP_14720	2.414e-190	612.0	COG0322@1|root,COG0322@2|Bacteria,2G651@200795|Chloroflexi	200795|Chloroflexi	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
CMS1_k127_4557161_16	886293.Sinac_4920	2.753e-14	86.0	COG0664@1|root,COG1136@1|root,COG0664@2|Bacteria,COG1136@2|Bacteria,2IZ14@203682|Planctomycetes	203682|Planctomycetes	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,cNMP_binding
CMS1_k127_4557161_13	1128421.JAGA01000002_gene171	1.214e-32	145.0	COG3428@1|root,COG3428@2|Bacteria,2NS34@2323|unclassified Bacteria	2|Bacteria	S	Bacterial PH domain	-	-	-	ko:K08981	-	-	-	-	ko00000	-	-	-	PASTA,bPH_2
CMS1_k127_4557161_1	880073.Calab_0633	1.724e-199	632.0	COG2403@1|root,COG2403@2|Bacteria,2NNTB@2323|unclassified Bacteria	2|Bacteria	S	cyclic 2,3-diphosphoglycerate synthetase activity	cpgS	-	-	ko:K05716	-	-	R03298	RC00900	ko00000,ko01000	-	-	-	cobW
CMS1_k127_4557161_18	1408303.JNJJ01000048_gene2706	0.000376	50.0	COG2318@1|root,COG2318@2|Bacteria,1VAGC@1239|Firmicutes,4HMA9@91061|Bacilli,1ZFRM@1386|Bacillus	91061|Bacilli	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
CMS1_k127_4557161_10	926569.ANT_30110	2.497e-47	180.0	COG0860@1|root,COG0860@2|Bacteria,2G7IE@200795|Chloroflexi	200795|Chloroflexi	M	PFAM cell wall hydrolase autolysin	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
CMS1_k127_4557161_15	1521187.JPIM01000013_gene2757	7.832e-22	106.0	COG1426@1|root,COG1426@2|Bacteria,2G773@200795|Chloroflexi,375R5@32061|Chloroflexia	32061|Chloroflexia	S	SMART helix-turn-helix domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4115,HTH_25
CMS1_k127_4557161_5	357808.RoseRS_3212	1.358e-102	340.0	COG0664@1|root,COG1136@1|root,COG0664@2|Bacteria,COG1136@2|Bacteria,2G6C9@200795|Chloroflexi,37685@32061|Chloroflexia	32061|Chloroflexia	V	ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,cNMP_binding
CMS1_k127_4557161_0	357808.RoseRS_1075	1.707e-245	783.0	COG0577@1|root,COG0577@2|Bacteria,2G68F@200795|Chloroflexi,376ZY@32061|Chloroflexia	32061|Chloroflexia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS1_k127_4557161_7	517418.Ctha_0151	2.01e-97	332.0	COG0205@1|root,COG0205@2|Bacteria,1FDFG@1090|Chlorobi	1090|Chlorobi	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	-	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
CMS1_k127_4557161_8	357808.RoseRS_3212	7.479e-86	291.0	COG0664@1|root,COG1136@1|root,COG0664@2|Bacteria,COG1136@2|Bacteria,2G6C9@200795|Chloroflexi,37685@32061|Chloroflexia	32061|Chloroflexia	V	ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,cNMP_binding
CMS1_k127_4557161_3	857087.Metme_3931	1.3e-174	575.0	COG0577@1|root,COG0577@2|Bacteria,1PJZX@1224|Proteobacteria,1RU56@1236|Gammaproteobacteria,1XDTW@135618|Methylococcales	135618|Methylococcales	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS1_k127_4557161_4	484770.UFO1_1183	2.153e-133	454.0	COG0577@1|root,COG0577@2|Bacteria,1U388@1239|Firmicutes,4H32X@909932|Negativicutes	909932|Negativicutes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS1_k127_4557161_9	765420.OSCT_2140	2.387e-63	236.0	COG0845@1|root,COG1566@1|root,COG0845@2|Bacteria,COG1566@2|Bacteria,2G8X1@200795|Chloroflexi,376YI@32061|Chloroflexia	32061|Chloroflexia	MV	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
CMS1_k127_4557161_14	926550.CLDAP_04490	5.181e-32	143.0	COG0823@1|root,COG3103@1|root,COG0823@2|Bacteria,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	NLPC_P60,Rick_17kDa_Anti,SH3_3
CMS1_k127_4557161_12	926550.CLDAP_18050	1.784e-35	155.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
CMS1_k127_4557161_11	926550.CLDAP_29840	5.875e-41	173.0	COG3023@1|root,COG4423@1|root,COG3023@2|Bacteria,COG4423@2|Bacteria	2|Bacteria	S	positive regulation of growth	-	-	-	ko:K19687	-	-	-	-	ko00000,ko02048	-	-	-	Amidase_2,PG_binding_1,PSK_trans_fac
CMS1_k127_4557161_6	926550.CLDAP_01930	1.998e-99	347.0	COG4713@1|root,COG4713@2|Bacteria,2GA9E@200795|Chloroflexi	2|Bacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2142
CMS1_k127_4557426_5	1499967.BAYZ01000054_gene4816	8.308e-90	306.0	COG0747@1|root,COG0747@2|Bacteria	2|Bacteria	E	dipeptide transport	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_4557426_2	324602.Caur_2783	1.059e-103	347.0	COG0601@1|root,COG0601@2|Bacteria,2G662@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_4557426_7	986075.CathTA2_2614	7.255e-87	297.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4HBB9@91061|Bacilli	91061|Bacilli	EP	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components	appC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
CMS1_k127_4557426_8	309801.trd_0073	1.863e-86	302.0	COG2234@1|root,COG2234@2|Bacteria,2G9MK@200795|Chloroflexi,27XKJ@189775|Thermomicrobia	189775|Thermomicrobia	S	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
CMS1_k127_4557426_9	1382356.JQMP01000003_gene2027	7.273e-65	229.0	COG0412@1|root,COG0412@2|Bacteria,2G9WC@200795|Chloroflexi,27Z94@189775|Thermomicrobia	189775|Thermomicrobia	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
CMS1_k127_4557426_11	926569.ANT_14200	1.129e-29	122.0	COG0347@1|root,COG0347@2|Bacteria	2|Bacteria	K	Belongs to the P(II) protein family	-	-	-	ko:K02806,ko:K04752	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	P-II
CMS1_k127_4557426_3	926569.ANT_02580	4.97e-103	350.0	COG0530@1|root,COG0530@2|Bacteria,2G7I2@200795|Chloroflexi	200795|Chloroflexi	P	PFAM sodium calcium exchanger membrane region	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
CMS1_k127_4557426_6	886293.Sinac_0183	1.277e-88	302.0	28I2M@1|root,32UVP@2|Bacteria,2J194@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF4058)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4058
CMS1_k127_4557426_1	357808.RoseRS_1075	3.759e-148	498.0	COG0577@1|root,COG0577@2|Bacteria,2G68F@200795|Chloroflexi,376ZY@32061|Chloroflexia	32061|Chloroflexia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS1_k127_4557426_4	357808.RoseRS_3212	8.911e-98	326.0	COG0664@1|root,COG1136@1|root,COG0664@2|Bacteria,COG1136@2|Bacteria,2G6C9@200795|Chloroflexi,37685@32061|Chloroflexia	32061|Chloroflexia	V	ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,cNMP_binding
CMS1_k127_4557426_10	485913.Krac_6152	6.432e-35	141.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_8,TetR_N
CMS1_k127_4557426_12	326427.Cagg_0214	2.134e-05	51.0	COG4848@1|root,COG4848@2|Bacteria,2GAD2@200795|Chloroflexi,375H8@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function (DUF1444)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1444
CMS1_k127_4557426_13	153721.MYP_3633	7.549e-05	48.0	COG1943@1|root,COG1943@2|Bacteria,4NQK5@976|Bacteroidetes,47QUD@768503|Cytophagia	976|Bacteroidetes	L	PFAM Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
CMS1_k127_4557426_0	357808.RoseRS_2459	2.771e-191	610.0	COG5012@1|root,COG5012@2|Bacteria,2G66F@200795|Chloroflexi,376VS@32061|Chloroflexia	32061|Chloroflexia	S	cobalamin binding	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding
CMS1_k127_4561374_0	247490.KSU1_D1011	2.173e-159	511.0	COG0462@1|root,COG0462@2|Bacteria,2IXI0@203682|Planctomycetes	2|Bacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran,Pribosyltran_N
CMS1_k127_4561374_2	1460634.JCM19037_121	3.306e-86	294.0	COG0179@1|root,COG0179@2|Bacteria,1TUD1@1239|Firmicutes,4HBI1@91061|Bacilli	91061|Bacilli	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
CMS1_k127_4561374_3	1235792.C808_04908	2.262e-48	186.0	COG1397@1|root,COG1397@2|Bacteria,1VJGR@1239|Firmicutes,24SQ2@186801|Clostridia	186801|Clostridia	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
CMS1_k127_4561374_1	1207063.P24_12622	3.496e-141	453.0	COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,2TQSB@28211|Alphaproteobacteria,2JR2I@204441|Rhodospirillales	204441|Rhodospirillales	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
CMS1_k127_4561374_4	330084.JNYZ01000038_gene4138	7.517e-27	114.0	COG1809@1|root,COG1809@2|Bacteria	2|Bacteria	S	phosphosulfolactate synthase activity	comA	-	4.4.1.19	ko:K08097	ko00680,ko01120,map00680,map01120	M00358	R07476	RC01799	ko00000,ko00001,ko00002,ko01000	-	-	-	ComA
CMS1_k127_4564041_2	1480694.DC28_05675	3.784e-106	350.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS1_k127_4564041_4	392499.Swit_3583	4.147e-62	228.0	COG0665@1|root,COG0665@2|Bacteria,1R4U7@1224|Proteobacteria,2U26T@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	D-amino acid	-	-	-	-	-	-	-	-	-	-	-	-	DAO
CMS1_k127_4564041_5	926560.KE387023_gene2611	2.268e-31	128.0	2CFP9@1|root,344WT@2|Bacteria,1WN5W@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4564041_1	382464.ABSI01000010_gene3494	9.923e-128	417.0	COG1063@1|root,COG1063@2|Bacteria	2|Bacteria	E	alcohol dehydrogenase	-	-	1.1.1.396	ko:K11337	ko00860,ko01110,map00860,map01110	-	R09055	RC01377	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_4564041_3	382464.ABSI01000010_gene3493	1.456e-102	348.0	COG1063@1|root,COG1063@2|Bacteria	2|Bacteria	E	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_4564041_6	1218086.BBNB01000016_gene1608	6.308e-14	81.0	COG2227@1|root,COG2519@1|root,COG2227@2|Bacteria,COG2519@2|Bacteria,1MXAK@1224|Proteobacteria,1RSIH@1236|Gammaproteobacteria,3WWXF@544|Citrobacter	1236|Gammaproteobacteria	HJ	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
CMS1_k127_4564041_0	1121904.ARBP01000027_gene729	5.51e-231	730.0	COG3250@1|root,COG3250@2|Bacteria,4NFPC@976|Bacteroidetes,47K4T@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
CMS1_k127_4564875_3	479434.Sthe_3397	5.208e-35	139.0	COG3839@1|root,COG3839@2|Bacteria	2|Bacteria	P	tungstate ion transport	tupC	-	3.6.3.55	ko:K06857	ko02010,map02010	M00186	R10531	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	ABC_tran
CMS1_k127_4564875_1	479434.Sthe_3396	3.6e-74	256.0	COG4662@1|root,COG4662@2|Bacteria,2G6ZF@200795|Chloroflexi,27Z7U@189775|Thermomicrobia	189775|Thermomicrobia	H	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K05773	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	BPD_transp_1
CMS1_k127_4564875_0	479434.Sthe_3395	1.368e-86	300.0	COG2998@1|root,COG2998@2|Bacteria,2G7MD@200795|Chloroflexi,27Z56@189775|Thermomicrobia	189775|Thermomicrobia	H	PBP superfamily domain	-	-	-	ko:K05772	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	PBP_like_2
CMS1_k127_4564875_2	477974.Daud_1894	2.602e-58	217.0	COG0303@1|root,COG1910@1|root,COG0303@2|Bacteria,COG1910@2|Bacteria,1TRH3@1239|Firmicutes,24ATZ@186801|Clostridia,2612F@186807|Peptococcaceae	186801|Clostridia	HP	TIGRFAM molybdenum cofactor synthesis	-	-	2.10.1.1	ko:K03750,ko:K07219	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N,PBP_like
CMS1_k127_4564875_4	1125725.HMPREF1325_1347	1.783e-10	71.0	COG0457@1|root,COG0457@2|Bacteria	1125725.HMPREF1325_1347|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4569461_8	1122221.JHVI01000001_gene1935	1.242e-68	239.0	COG0174@1|root,COG0174@2|Bacteria,1WM8G@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Glutamine synthetase, catalytic domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C
CMS1_k127_4569461_5	926550.CLDAP_37410	3.636e-81	276.0	COG1136@1|root,COG1136@2|Bacteria,2G8HT@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_4569461_1	118161.KB235922_gene5012	1.741e-220	711.0	COG0577@1|root,COG0577@2|Bacteria,1G04T@1117|Cyanobacteria	1117|Cyanobacteria	V	ABC-type transport system involved in lipoprotein release permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS1_k127_4569461_7	316274.Haur_3102	5.166e-70	269.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,2GABQ@200795|Chloroflexi,3751C@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3369,GAF,GAF_2,HATPase_c,HisKA,PAS_4
CMS1_k127_4569461_4	760568.Desku_0806	3.69e-90	307.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,260BA@186807|Peptococcaceae	186801|Clostridia	C	electron transfer flavoprotein, alpha subunit	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha,Fer4
CMS1_k127_4569461_10	909663.KI867150_gene2942	1.401e-55	203.0	COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,42RCI@68525|delta/epsilon subdivisions,2WM55@28221|Deltaproteobacteria,2MQDQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM Electron transfer flavoprotein	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
CMS1_k127_4569461_3	926550.CLDAP_05970	1.03e-188	596.0	COG1960@1|root,COG1960@2|Bacteria,2G65J@200795|Chloroflexi	200795|Chloroflexi	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS1_k127_4569461_13	1128421.JAGA01000002_gene667	2.222e-13	83.0	COG0457@1|root,COG5635@1|root,COG0457@2|Bacteria,COG5635@2|Bacteria	2|Bacteria	T	Nacht domain	-	-	-	-	-	-	-	-	-	-	-	-	NACHT,TPR_16,TPR_19,TPR_2,TPR_8,Trypsin_2
CMS1_k127_4569461_0	1480694.DC28_03555	3.15e-266	837.0	COG1523@1|root,COG1523@2|Bacteria,2J61K@203691|Spirochaetes	203691|Spirochaetes	G	Belongs to the glycosyl hydrolase 13 family	glgX	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
CMS1_k127_4569461_11	886293.Sinac_3291	4.12e-44	166.0	COG4636@1|root,COG4636@2|Bacteria,2J0XX@203682|Planctomycetes	203682|Planctomycetes	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
CMS1_k127_4569461_2	1521187.JPIM01000123_gene3610	7.897e-219	698.0	COG0272@1|root,COG0272@2|Bacteria,2G5TK@200795|Chloroflexi,3756T@32061|Chloroflexia	32061|Chloroflexia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
CMS1_k127_4569461_6	383372.Rcas_0482	1.211e-78	268.0	COG2006@1|root,COG2006@2|Bacteria	2|Bacteria	U	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,CBM9_2,DUF362
CMS1_k127_4569461_12	1123288.SOV_4c07160	3.811e-39	152.0	COG0251@1|root,COG0251@2|Bacteria,1V6G4@1239|Firmicutes,4H8F8@909932|Negativicutes	909932|Negativicutes	J	YjgF/chorismate_mutase-like, putative endoribonuclease	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
CMS1_k127_4569461_9	1267211.KI669560_gene610	3.523e-65	232.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS1_k127_4569461_15	1403819.BATR01000051_gene1505	0.0005064	46.0	COG1680@1|root,COG1680@2|Bacteria,46TM4@74201|Verrucomicrobia	74201|Verrucomicrobia	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS1_k127_4583865_4	383372.Rcas_3701	5.661e-62	225.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GAAG@200795|Chloroflexi,374S4@32061|Chloroflexia	32061|Chloroflexia	K	transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,TPR_12,Trans_reg_C
CMS1_k127_4583865_0	1415780.JPOG01000001_gene1457	2.551e-108	357.0	COG2267@1|root,COG2267@2|Bacteria,1MUG8@1224|Proteobacteria,1RMFE@1236|Gammaproteobacteria,1X43J@135614|Xanthomonadales	135614|Xanthomonadales	I	Alpha beta hydrolase	cpo	-	1.11.1.10	ko:K00433	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1
CMS1_k127_4583865_3	926560.KE387027_gene519	2.451e-70	245.0	COG2045@1|root,COG2045@2|Bacteria,1WMIA@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	2-phosphosulpholactate phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	2-ph_phosp
CMS1_k127_4583865_1	1444309.JAQG01000065_gene2431	3.703e-105	353.0	COG3173@1|root,COG3173@2|Bacteria,1UIXX@1239|Firmicutes,4ISW9@91061|Bacilli,26VY7@186822|Paenibacillaceae	91061|Bacilli	S	Protein of unknown function (DUF1679)	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS1_k127_4583865_2	344747.PM8797T_06255	3.671e-96	322.0	COG4427@1|root,COG4427@2|Bacteria	2|Bacteria	S	Uncharacterized protein conserved in bacteria (DUF2332)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2332
CMS1_k127_4598498_7	316274.Haur_3574	4.89e-63	226.0	291JP@1|root,2ZP62@2|Bacteria,2GASU@200795|Chloroflexi,3778Y@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4598498_3	316274.Haur_3576	6.816e-134	439.0	COG0438@1|root,COG0438@2|Bacteria,2G9B8@200795|Chloroflexi,376I5@32061|Chloroflexia	32061|Chloroflexia	H	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS1_k127_4598498_1	316274.Haur_3583	2.111e-143	465.0	COG1215@1|root,COG1215@2|Bacteria,2GAJA@200795|Chloroflexi,376HJ@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
CMS1_k127_4598498_18	1449350.OCH239_10180	7.469e-11	64.0	COG3464@1|root,COG3464@2|Bacteria,1N2KA@1224|Proteobacteria,2TVCT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase	MA20_12025	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,zf-ISL3
CMS1_k127_4598498_6	1121957.ATVL01000006_gene2934	1.056e-93	321.0	COG1409@1|root,COG1520@1|root,COG1409@2|Bacteria,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	phoA	-	3.1.3.2	ko:K14379	ko00740,ko01100,ko04142,ko04380,ko05323,map00740,map01100,map04142,map04380,map05323	-	R00548	RC00017	ko00000,ko00001,ko01000	-	-	-	Metallophos,PQQ_2,PQQ_3
CMS1_k127_4598498_9	402777.KB235899_gene4898	2.764e-57	224.0	COG2931@1|root,COG3210@1|root,COG3266@1|root,COG3391@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3266@2|Bacteria,COG3391@2|Bacteria,1G4T5@1117|Cyanobacteria,1HHYV@1150|Oscillatoriales	1117|Cyanobacteria	U	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF4347,Haemagg_act,HemolysinCabind
CMS1_k127_4598498_11	644968.DFW101_1113	1.035e-47	181.0	COG0745@1|root,COG0745@2|Bacteria,1MWZ5@1224|Proteobacteria,42QTM@68525|delta/epsilon subdivisions,2WN5R@28221|Deltaproteobacteria,2MAN8@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Two component transcriptional regulator, winged helix family	kdpE	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_4598498_14	357808.RoseRS_0196	2.215e-32	141.0	COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,2G66G@200795|Chloroflexi,3754U@32061|Chloroflexia	32061|Chloroflexia	T	SMART PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA,PAS
CMS1_k127_4598498_13	386456.JQKN01000004_gene176	4.479e-40	172.0	COG0642@1|root,COG0784@1|root,arCOG02333@2157|Archaea,arCOG02358@2157|Archaea	2157|Archaea	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GAF_3,HATPase_c,HisKA,HisKA_4TM,PAS,PAS_3,PAS_4,PAS_9,Response_reg
CMS1_k127_4598498_15	316274.Haur_2729	1.21e-30	141.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G8GW@200795|Chloroflexi,3776B@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
CMS1_k127_4598498_10	479434.Sthe_0243	2.668e-56	204.0	COG2197@1|root,COG2197@2|Bacteria,2G6C5@200795|Chloroflexi	200795|Chloroflexi	K	COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS1_k127_4598498_0	1089553.Tph_c18770	0.0	1215.0	COG2132@1|root,COG2132@2|Bacteria,1V17J@1239|Firmicutes,24FAM@186801|Clostridia	186801|Clostridia	Q	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	SdrD_B
CMS1_k127_4598498_5	1120949.KB903316_gene79	5.461e-106	358.0	COG2132@1|root,COG2132@2|Bacteria,2IAV7@201174|Actinobacteria	201174|Actinobacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
CMS1_k127_4598498_2	543632.JOJL01000023_gene1812	3.447e-138	454.0	COG2132@1|root,COG2132@2|Bacteria,2IDXQ@201174|Actinobacteria	201174|Actinobacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_3
CMS1_k127_4598498_8	1120949.KB903316_gene77	1.982e-58	228.0	COG2132@1|root,COG2132@2|Bacteria,2IQHJ@201174|Actinobacteria	201174|Actinobacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_3
CMS1_k127_4598498_17	1120949.KB903316_gene76	3.327e-18	90.0	2DQ3J@1|root,334KB@2|Bacteria,2GZZK@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4598498_16	1296415.JACC01000052_gene3696	5.689e-22	108.0	COG1470@1|root,COG2356@1|root,COG4733@1|root,COG1470@2|Bacteria,COG2356@2|Bacteria,COG4733@2|Bacteria,4PKY7@976|Bacteroidetes,1IJH4@117743|Flavobacteriia,2YICG@290174|Aquimarina	976|Bacteroidetes	L	Metallo-peptidase family M12B Reprolysin-like	-	-	-	-	-	-	-	-	-	-	-	-	MAM,Reprolysin_4,fn3
CMS1_k127_4598498_19	1116472.MGMO_91c00040	2.886e-06	57.0	COG2372@1|root,COG2372@2|Bacteria,1N8WP@1224|Proteobacteria,1RUCK@1236|Gammaproteobacteria,1XFR1@135618|Methylococcales	135618|Methylococcales	S	CopC domain	-	-	-	ko:K07156	-	-	-	-	ko00000,ko02000	9.B.62.2	-	-	CopC
CMS1_k127_4598498_12	485913.Krac_7870	1.302e-43	182.0	COG1276@1|root,COG2372@1|root,COG1276@2|Bacteria,COG2372@2|Bacteria,2G8KM@200795|Chloroflexi	200795|Chloroflexi	P	PFAM copper resistance protein CopC	-	-	-	-	-	-	-	-	-	-	-	-	CopC,CopD
CMS1_k127_4598498_4	697282.Mettu_2045	2.782e-115	382.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria,1XFQY@135618|Methylococcales	135618|Methylococcales	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
CMS1_k127_459997_4	1122176.KB903538_gene1452	6.563e-15	85.0	28X89@1|root,2ZJ6D@2|Bacteria,4NM59@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS1_k127_459997_1	926550.CLDAP_02170	2.122e-70	242.0	arCOG03391@1|root,33KRQ@2|Bacteria	2|Bacteria	S	LexA-binding, inner membrane-associated putative hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	YdjM
CMS1_k127_459997_2	1165096.ARWF01000001_gene2108	9.887e-43	169.0	COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,2VM6F@28216|Betaproteobacteria,2KNQP@206350|Nitrosomonadales	206350|Nitrosomonadales	T	PFAM Protein phosphatase	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2,SpoIIE
CMS1_k127_459997_5	526227.Mesil_0032	3.911e-06	50.0	2A1Y8@1|root,30Q7R@2|Bacteria,1WMYR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_459997_3	383372.Rcas_2349	8.757e-24	102.0	COG2886@1|root,COG2886@2|Bacteria	2|Bacteria	E	Uncharacterised protein family (UPF0175)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0175
CMS1_k127_459997_0	1499967.BAYZ01000015_gene6575	2.745e-89	301.0	COG0846@1|root,COG0846@2|Bacteria,2NPJR@2323|unclassified Bacteria	2|Bacteria	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
CMS1_k127_4605817_7	926550.CLDAP_12370	2.507e-110	379.0	COG5305@1|root,COG5305@2|Bacteria,2G7EE@200795|Chloroflexi	200795|Chloroflexi	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4605817_5	926550.CLDAP_12360	2.649e-154	507.0	COG2723@1|root,COG2723@2|Bacteria	2|Bacteria	G	beta-glucosidase activity	-	-	3.2.1.21	ko:K05350,ko:K21000	ko00460,ko00500,ko00940,ko01100,ko01110,ko02025,map00460,map00500,map00940,map01100,map01110,map02025	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH39	-	Cellulase,Glyco_hydro_1
CMS1_k127_4605817_8	926550.CLDAP_07940	3.787e-87	305.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	ko:K14340	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	PMT_2
CMS1_k127_4605817_6	926550.CLDAP_05570	1.763e-137	451.0	COG1921@1|root,COG1921@2|Bacteria,2G5VV@200795|Chloroflexi	200795|Chloroflexi	H	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
CMS1_k127_4605817_0	326427.Cagg_2702	0.0	1056.0	COG0205@1|root,COG0205@2|Bacteria,2G62R@200795|Chloroflexi,375FT@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	-	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
CMS1_k127_4605817_19	648757.Rvan_2917	4.261e-06	58.0	COG0745@1|root,COG0745@2|Bacteria,1MU3A@1224|Proteobacteria,2TR97@28211|Alphaproteobacteria,3N6G6@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	K	Transcriptional regulator	mtrA	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_4605817_11	926569.ANT_04400	6.593e-77	269.0	COG0454@1|root,COG1247@1|root,COG0456@2|Bacteria,COG1247@2|Bacteria,2G6N6@200795|Chloroflexi	200795|Chloroflexi	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS1_k127_4605817_3	926569.ANT_00880	2.606e-171	555.0	COG0488@1|root,COG0488@2|Bacteria,2G5VD@200795|Chloroflexi	200795|Chloroflexi	S	PFAM ABC transporter related	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
CMS1_k127_4605817_9	716544.wcw_1745	4.618e-79	273.0	COG0566@1|root,COG0566@2|Bacteria,2JFQK@204428|Chlamydiae	204428|Chlamydiae	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	spoU_1	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
CMS1_k127_4605817_14	1173024.KI912149_gene6258	4.83e-44	165.0	COG0454@1|root,COG0456@2|Bacteria,1GKU0@1117|Cyanobacteria,1JMQW@1189|Stigonemataceae	1117|Cyanobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS1_k127_4605817_12	926550.CLDAP_35280	7.032e-69	242.0	COG0454@1|root,COG0456@2|Bacteria,2G91C@200795|Chloroflexi	200795|Chloroflexi	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS1_k127_4605817_10	383372.Rcas_2582	1.858e-77	273.0	COG0116@1|root,COG0116@2|Bacteria,2G8DP@200795|Chloroflexi,375KK@32061|Chloroflexia	32061|Chloroflexia	L	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	UPF0020
CMS1_k127_4605817_4	1521187.JPIM01000067_gene1071	1.079e-158	515.0	COG1160@1|root,COG1160@2|Bacteria,2G5M0@200795|Chloroflexi,375A1@32061|Chloroflexia	32061|Chloroflexia	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
CMS1_k127_4605817_18	1484460.JSWG01000015_gene990	5.535e-14	83.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_P460,F5_F8_type_C,Glyco_hydro_98C,Glyco_hydro_98M
CMS1_k127_4605817_20	511051.CSE_02410	1.505e-05	57.0	COG1361@1|root,COG3210@1|root,COG4719@1|root,COG1361@2|Bacteria,COG3210@2|Bacteria,COG4719@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11
CMS1_k127_4605817_2	316274.Haur_3626	5.324e-232	732.0	COG1132@1|root,COG1132@2|Bacteria,2G5QH@200795|Chloroflexi,377YK@32061|Chloroflexia	32061|Chloroflexia	P	PFAM ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS1_k127_4605817_1	316274.Haur_3627	2.954e-271	847.0	COG1132@1|root,COG1132@2|Bacteria,2G66A@200795|Chloroflexi,37630@32061|Chloroflexia	32061|Chloroflexia	V	PFAM ABC transporter transmembrane region	-	-	-	ko:K06147,ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS1_k127_4605817_13	330214.NIDE0036	5.007e-51	185.0	COG2259@1|root,COG2259@2|Bacteria,3J13I@40117|Nitrospirae	40117|Nitrospirae	S	Evidence 4 Homologs of previously reported genes of	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
CMS1_k127_4605817_15	926554.KI912671_gene194	1.081e-39	152.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
CMS1_k127_4605817_16	642492.Clole_2616	3.386e-24	107.0	29W5C@1|root,309R7@2|Bacteria,1UFWQ@1239|Firmicutes,24KA7@186801|Clostridia	186801|Clostridia	S	Streptomycin adenylyltransferase	-	-	-	ko:K05593	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Adenyl_transf
CMS1_k127_4606610_5	1304880.JAGB01000002_gene2308	6.193e-63	222.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia	186801|Clostridia	P	ABC-type dipeptide oligopeptide nickel transport	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
CMS1_k127_4606610_3	697281.Mahau_1199	8.082e-116	381.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,42GB7@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	appB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_4606610_1	697281.Mahau_1197	6.83e-178	579.0	COG0747@1|root,COG0747@2|Bacteria,1W71F@1239|Firmicutes,24D0K@186801|Clostridia,42J19@68295|Thermoanaerobacterales	186801|Clostridia	E	COGs COG0747 ABC-type dipeptide transport system periplasmic component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_4606610_0	926550.CLDAP_17290	4.761e-260	808.0	COG3119@1|root,COG3119@2|Bacteria,2G7YZ@200795|Chloroflexi	200795|Chloroflexi	P	PFAM Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS1_k127_4606610_4	1120950.KB892746_gene3503	6.567e-107	352.0	COG5285@1|root,COG5285@2|Bacteria	2|Bacteria	Q	dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
CMS1_k127_4606610_2	697281.Mahau_1212	5.559e-134	434.0	COG0673@1|root,COG0673@2|Bacteria,1VRY8@1239|Firmicutes,24PM0@186801|Clostridia	186801|Clostridia	S	COGs COG0673 dehydrogenase and related protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_4622582_1	326427.Cagg_3070	8.24e-143	460.0	COG0173@1|root,COG0173@2|Bacteria,2G5RX@200795|Chloroflexi,374WK@32061|Chloroflexia	32061|Chloroflexia	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
CMS1_k127_4622582_3	545694.TREPR_2318	5.26e-60	224.0	COG1235@1|root,COG1235@2|Bacteria,2J5C5@203691|Spirochaetes	203691|Spirochaetes	S	Metallo-beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
CMS1_k127_4622582_0	926569.ANT_21050	1.403e-220	702.0	COG0402@1|root,COG1437@1|root,COG0402@2|Bacteria,COG1437@2|Bacteria,2G6DG@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,CYTH
CMS1_k127_4622582_2	1128421.JAGA01000002_gene1035	2.055e-112	377.0	COG0303@1|root,COG0303@2|Bacteria,2NP4N@2323|unclassified Bacteria	2|Bacteria	H	MoeA N-terminal region (domain I and II)	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
CMS1_k127_4628428_4	926550.CLDAP_38380	1.998e-180	576.0	COG1653@1|root,COG1653@2|Bacteria,2G82H@200795|Chloroflexi	200795|Chloroflexi	G	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K02027,ko:K10188	ko02010,map02010	M00199,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.4	-	-	SBP_bac_1,SBP_bac_8
CMS1_k127_4628428_6	63737.Npun_F4445	4.212e-137	445.0	COG0075@1|root,COG0075@2|Bacteria,1G2P6@1117|Cyanobacteria,1HM90@1161|Nostocales	1117|Cyanobacteria	E	PFAM Aminotransferase	spt	-	2.6.1.44,2.6.1.45,2.6.1.51	ko:K00830	ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	M00346,M00532	R00369,R00372,R00585,R00588	RC00006,RC00008,RC00018	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
CMS1_k127_4628428_5	357808.RoseRS_2189	1.843e-151	484.0	COG0673@1|root,COG0673@2|Bacteria,2G5VJ@200795|Chloroflexi	200795|Chloroflexi	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_4628428_7	926550.CLDAP_03590	8.723e-121	391.0	COG4813@1|root,COG4813@2|Bacteria,2G5QZ@200795|Chloroflexi	200795|Chloroflexi	G	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	ThuA
CMS1_k127_4628428_10	1174528.JH992898_gene2677	4.871e-82	282.0	COG3173@1|root,COG3173@2|Bacteria,1GKJB@1117|Cyanobacteria,1JMB4@1189|Stigonemataceae	1117|Cyanobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS1_k127_4628428_9	1382306.JNIM01000001_gene3158	7.428e-84	293.0	COG3842@1|root,COG3842@2|Bacteria,2G5X9@200795|Chloroflexi	2|Bacteria	P	PFAM ABC transporter related	-	-	-	ko:K10111,ko:K10112,ko:K17240	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00204,M00206,M00207,M00491,M00599,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.1,3.A.1.1.38	-	-	ABC_tran,TOBE_2
CMS1_k127_4628428_0	1173026.Glo7428_0407	1.713e-239	749.0	COG2317@1|root,COG2317@2|Bacteria,1G143@1117|Cyanobacteria	1117|Cyanobacteria	E	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues	cxp	-	3.4.17.19	ko:K01299	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M32
CMS1_k127_4628428_12	357808.RoseRS_2041	1.115e-61	226.0	COG1697@1|root,COG1697@2|Bacteria,2GBTD@200795|Chloroflexi,376KT@32061|Chloroflexia	32061|Chloroflexia	L	DNA topoisomerase VI subunit A	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4628428_11	383372.Rcas_3019	1.679e-62	228.0	COG1697@1|root,COG1697@2|Bacteria,2GAAB@200795|Chloroflexi,376R1@32061|Chloroflexia	32061|Chloroflexia	L	DNA topoisomerase VI subunit A	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4628428_13	383372.Rcas_3020	9.862e-53	192.0	2F8F0@1|root,340TR@2|Bacteria,2GA68@200795|Chloroflexi,3774A@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4628428_2	357808.RoseRS_2044	2.729e-229	724.0	COG0367@1|root,COG0367@2|Bacteria,2G7R3@200795|Chloroflexi,3766Q@32061|Chloroflexia	32061|Chloroflexia	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
CMS1_k127_4628428_8	1122604.JONR01000025_gene4558	1.154e-93	316.0	COG4106@1|root,COG4106@2|Bacteria,1Q2Y3@1224|Proteobacteria,1S2MJ@1236|Gammaproteobacteria,1X6B4@135614|Xanthomonadales	135614|Xanthomonadales	S	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS1_k127_4628428_1	266117.Rxyl_1005	2.765e-232	735.0	28HJF@1|root,2Z7UK@2|Bacteria,2ICK7@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4628428_3	383372.Rcas_1569	3.46e-192	627.0	COG1404@1|root,COG1404@2|Bacteria,2G80X@200795|Chloroflexi,375FY@32061|Chloroflexia	32061|Chloroflexia	O	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
CMS1_k127_4628428_14	525904.Tter_2546	0.0003393	47.0	COG0589@1|root,COG0589@2|Bacteria,2NRGN@2323|unclassified Bacteria	2|Bacteria	T	PFAM UspA domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS1_k127_4632399_1	697284.ERIC2_c33950	3.244e-42	159.0	COG1175@1|root,COG1175@2|Bacteria,1TPTZ@1239|Firmicutes,4HAIH@91061|Bacilli,276G2@186822|Paenibacillaceae	91061|Bacilli	G	Binding-protein-dependent transport system inner membrane component	ugpA7	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_4632399_0	525904.Tter_2040	9.833e-89	301.0	COG0395@1|root,COG0395@2|Bacteria	2|Bacteria	P	glycerophosphodiester transmembrane transport	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_4632399_2	661478.OP10G_0717	7.224e-36	153.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K02025,ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
CMS1_k127_4632399_3	936136.ARRT01000003_gene6316	0.000314	48.0	COG3119@1|root,COG3119@2|Bacteria,1MV0B@1224|Proteobacteria,2TRI6@28211|Alphaproteobacteria,4B825@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CMS1_k127_4648897_4	187272.Mlg_0137	1.712e-05	55.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,1RYBJ@1236|Gammaproteobacteria,1WX72@135613|Chromatiales	135613|Chromatiales	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glycos_transf_1
CMS1_k127_4648897_0	926550.CLDAP_02020	3.328e-167	546.0	COG1520@1|root,COG1520@2|Bacteria,2G93W@200795|Chloroflexi	200795|Chloroflexi	S	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
CMS1_k127_4648897_5	679926.Mpet_1402	9.713e-05	50.0	COG0500@1|root,arCOG04340@2157|Archaea,arCOG04347@2157|Archaea,2XWDS@28890|Euryarchaeota,2N9F1@224756|Methanomicrobia	224756|Methanomicrobia	Q	Methionine biosynthesis protein MetW	-	-	2.1.1.294,2.7.1.181	ko:K18827	-	-	R10657,R10658	RC00002,RC00003,RC00078,RC03220	ko00000,ko01000,ko01005	-	-	-	Methyltransf_11
CMS1_k127_4648897_1	644282.Deba_0452	1.827e-77	272.0	COG0438@1|root,COG0438@2|Bacteria,1RM3H@1224|Proteobacteria,42WAY@68525|delta/epsilon subdivisions,2WRXX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
CMS1_k127_4648897_2	56110.Oscil6304_0196	2.226e-72	254.0	COG0500@1|root,COG2226@2|Bacteria,1G681@1117|Cyanobacteria,1HBRE@1150|Oscillatoriales	1117|Cyanobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,TPR_11,TPR_2
CMS1_k127_4648897_3	221288.JH992901_gene5376	5.244e-60	216.0	COG0438@1|root,COG0438@2|Bacteria,1G3U9@1117|Cyanobacteria	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CMS1_k127_4656194_14	1499967.BAYZ01000147_gene726	2.104e-29	131.0	COG0664@1|root,COG1752@1|root,COG3437@1|root,COG0664@2|Bacteria,COG1752@2|Bacteria,COG3437@2|Bacteria	2|Bacteria	T	response regulator, receiver	-	-	3.1.3.3	ko:K07001,ko:K07315,ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03021	-	-	-	HTH_Crp_2,Patatin,Response_reg,SpoIIE,cNMP_binding
CMS1_k127_4656194_11	1499967.BAYZ01000147_gene726	3.126e-52	205.0	COG0664@1|root,COG1752@1|root,COG3437@1|root,COG0664@2|Bacteria,COG1752@2|Bacteria,COG3437@2|Bacteria	2|Bacteria	T	response regulator, receiver	-	-	3.1.3.3	ko:K07001,ko:K07315,ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03021	-	-	-	HTH_Crp_2,Patatin,Response_reg,SpoIIE,cNMP_binding
CMS1_k127_4656194_13	1128421.JAGA01000002_gene728	2.087e-32	132.0	2DQ01@1|root,32UN7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4656194_0	309799.DICTH_1454	3.519e-286	903.0	COG0495@1|root,COG0495@2|Bacteria	2|Bacteria	J	leucyl-tRNA aminoacylation	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iAF987.Gmet_2300	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
CMS1_k127_4656194_10	386456.JQKN01000013_gene2982	2.308e-59	213.0	arCOG01788@1|root,arCOG01788@2157|Archaea,2XXVU@28890|Euryarchaeota	28890|Euryarchaeota	Q	Methyltransferase	-	-	-	ko:K15256	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_25
CMS1_k127_4656194_1	485913.Krac_9333	7.249e-264	824.0	COG0119@1|root,COG0119@2|Bacteria,2G5V9@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
CMS1_k127_4656194_9	797299.HALLA_03760	1.793e-83	287.0	COG0697@1|root,arCOG00271@2157|Archaea,2XY2J@28890|Euryarchaeota,23Z1Z@183963|Halobacteria	183963|Halobacteria	G	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS1_k127_4656194_7	1469245.JFBG01000016_gene949	1.098e-104	346.0	COG1940@1|root,COG1940@2|Bacteria,1NSQA@1224|Proteobacteria,1S0A5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	GK	ROK family	-	-	2.7.1.63	ko:K00886	ko00010,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R02187,R02189	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
CMS1_k127_4656194_8	1123252.ATZF01000007_gene162	1.77e-99	333.0	COG0122@1|root,COG0122@2|Bacteria,1TQAF@1239|Firmicutes,4HBYM@91061|Bacilli,27BP3@186824|Thermoactinomycetaceae	91061|Bacilli	L	endonuclease III	alkA	-	3.2.2.21	ko:K01247,ko:K13529	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	AlkA_N,HhH-GPD,OGG_N
CMS1_k127_4656194_6	1499967.BAYZ01000060_gene6006	2.735e-108	357.0	COG0350@1|root,COG2207@1|root,COG0350@2|Bacteria,COG2207@2|Bacteria,2NPJ5@2323|unclassified Bacteria	2|Bacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ada	-	2.1.1.63	ko:K00567,ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	DNA_binding_1,HTH_18,Methyltransf_1N
CMS1_k127_4656194_12	357808.RoseRS_3186	2.57e-33	140.0	2ECS5@1|root,336PT@2|Bacteria,2G96H@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF4129)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
CMS1_k127_4656194_3	357808.RoseRS_3184	4.089e-145	466.0	COG0714@1|root,COG0714@2|Bacteria,2G8BI@200795|Chloroflexi,377XH@32061|Chloroflexia	32061|Chloroflexia	S	PFAM ATPase associated with various cellular activities, AAA_3	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS1_k127_4656194_5	357808.RoseRS_3183	1.369e-114	383.0	COG1721@1|root,COG1721@2|Bacteria,2G7JJ@200795|Chloroflexi	200795|Chloroflexi	M	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CMS1_k127_4656194_16	867845.KI911784_gene1691	8.359e-21	99.0	COG0484@1|root,COG0484@2|Bacteria,2G5NV@200795|Chloroflexi,374VC@32061|Chloroflexia	32061|Chloroflexia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
CMS1_k127_4656194_19	8932.XP_005504135.1	4.516e-05	53.0	KOG3689@1|root,KOG3689@2759|Eukaryota,38BQB@33154|Opisthokonta,3B9XB@33208|Metazoa,3CSEF@33213|Bilateria,4803J@7711|Chordata,491P8@7742|Vertebrata,4GPHZ@8782|Aves	33208|Metazoa	T	Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase	PDE11A	GO:0000166,GO:0003674,GO:0003824,GO:0004112,GO:0004114,GO:0004115,GO:0004118,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005758,GO:0005829,GO:0006091,GO:0006119,GO:0006122,GO:0006123,GO:0006139,GO:0006163,GO:0006195,GO:0006198,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0007186,GO:0008081,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009154,GO:0009161,GO:0009166,GO:0009167,GO:0009187,GO:0009199,GO:0009205,GO:0009214,GO:0009259,GO:0009261,GO:0009893,GO:0009966,GO:0009968,GO:0009987,GO:0010604,GO:0010646,GO:0010648,GO:0010752,GO:0010754,GO:0010941,GO:0010942,GO:0010950,GO:0010952,GO:0015980,GO:0016310,GO:0016787,GO:0016788,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019222,GO:0019438,GO:0019439,GO:0019637,GO:0019646,GO:0019693,GO:0022900,GO:0022904,GO:0023051,GO:0023052,GO:0023057,GO:0030162,GO:0030551,GO:0030552,GO:0030553,GO:0030554,GO:0031323,GO:0031325,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0032268,GO:0032270,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0036477,GO:0042578,GO:0042773,GO:0042775,GO:0042981,GO:0043025,GO:0043065,GO:0043067,GO:0043068,GO:0043085,GO:0043167,GO:0043168,GO:0043204,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043280,GO:0043281,GO:0043949,GO:0043951,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044297,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045333,GO:0045862,GO:0046034,GO:0046058,GO:0046068,GO:0046069,GO:0046434,GO:0046483,GO:0046700,GO:0047555,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051336,GO:0051345,GO:0051716,GO:0052547,GO:0052548,GO:0055086,GO:0055114,GO:0060255,GO:0065007,GO:0065009,GO:0070013,GO:0071704,GO:0072521,GO:0072523,GO:0080090,GO:0097159,GO:0097367,GO:0097458,GO:1901135,GO:1901136,GO:1901265,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1902531,GO:1902532,GO:2000116,GO:2001056	3.1.4.17,3.1.4.35	ko:K13298	ko00230,ko04934,ko05032,map00230,map04934,map05032	-	R00191,R01234	RC00296	ko00000,ko00001,ko01000	-	-	-	GAF,PDEase_I
CMS1_k127_4656194_4	439235.Dalk_2094	1.724e-141	476.0	COG0664@1|root,COG1752@1|root,COG0664@2|Bacteria,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,42RSN@68525|delta/epsilon subdivisions,2WNDI@28221|Deltaproteobacteria,2MPUY@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin,cNMP_binding
CMS1_k127_4656194_2	765420.OSCT_0643	2.386e-175	574.0	COG4585@1|root,COG4585@2|Bacteria,2G7W5@200795|Chloroflexi,3767N@32061|Chloroflexia	32061|Chloroflexia	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4656194_15	926569.ANT_16820	3.872e-22	97.0	COG1408@1|root,COG1408@2|Bacteria,2G6VC@200795|Chloroflexi	200795|Chloroflexi	S	PFAM metallophosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
CMS1_k127_4667750_11	543632.JOJL01000056_gene313	9.4e-14	74.0	COG5659@1|root,COG5659@2|Bacteria,2GIU9@201174|Actinobacteria,4DC2W@85008|Micromonosporales	201174|Actinobacteria	L	FOG Transposase	insA	-	-	-	-	-	-	-	-	-	-	-	DDE_5
CMS1_k127_4667750_1	1382306.JNIM01000001_gene1763	1.814e-110	366.0	COG4586@1|root,COG4586@2|Bacteria,2G7JN@200795|Chloroflexi	200795|Chloroflexi	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
CMS1_k127_4667750_6	189426.PODO_11575	4.966e-65	231.0	COG4587@1|root,COG4587@2|Bacteria,1V4UC@1239|Firmicutes,4HMTT@91061|Bacilli,26WCZ@186822|Paenibacillaceae	91061|Bacilli	S	transport system permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
CMS1_k127_4667750_7	189426.PODO_11580	1.348e-55	203.0	COG3694@1|root,COG3694@2|Bacteria,1UZ6K@1239|Firmicutes,4HCYU@91061|Bacilli,276WH@186822|Paenibacillaceae	91061|Bacilli	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
CMS1_k127_4667750_9	326297.Sama_0493	1.08e-17	86.0	COG0640@1|root,COG0640@2|Bacteria,1MZT1@1224|Proteobacteria,1SAI5@1236|Gammaproteobacteria,2QCJ1@267890|Shewanellaceae	1236|Gammaproteobacteria	K	PFAM regulatory protein, ArsR	arsR	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5,LMWPc
CMS1_k127_4667750_5	926550.CLDAP_37010	3.597e-75	262.0	COG0500@1|root,COG2226@2|Bacteria,2G6GD@200795|Chloroflexi	200795|Chloroflexi	Q	Methyltransferase type 11	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
CMS1_k127_4667750_2	926550.CLDAP_25450	2.853e-108	365.0	COG1674@1|root,COG1674@2|Bacteria,2G5XC@200795|Chloroflexi	2|Bacteria	D	PFAM cell divisionFtsK SpoIIIE	ftsK	GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
CMS1_k127_4667750_8	357808.RoseRS_0570	2.522e-55	203.0	COG2243@1|root,COG2243@2|Bacteria,2G7XJ@200795|Chloroflexi,3764Z@32061|Chloroflexia	32061|Chloroflexia	H	PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase	-	-	2.1.1.130,2.1.1.151	ko:K03394	ko00860,ko01100,map00860,map01100	-	R03948,R05808	RC00003,RC01035,RC01662	ko00000,ko00001,ko01000	-	-	-	TP_methylase
CMS1_k127_4667750_4	383372.Rcas_1877	2.057e-87	297.0	COG0639@1|root,COG0639@2|Bacteria,2G71P@200795|Chloroflexi,375UU@32061|Chloroflexia	32061|Chloroflexia	T	PFAM metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
CMS1_k127_4667750_0	1123073.KB899241_gene3250	8.1e-119	392.0	COG3239@1|root,COG3239@2|Bacteria,1MY4I@1224|Proteobacteria,1S0IS@1236|Gammaproteobacteria,1X4IQ@135614|Xanthomonadales	135614|Xanthomonadales	I	Fatty acid desaturase	-	-	1.14.19.23,1.14.19.45	ko:K10255	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
CMS1_k127_4667750_3	306281.AJLK01000099_gene5396	3.877e-94	315.0	COG0842@1|root,COG0842@2|Bacteria	2|Bacteria	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC_tran
CMS1_k127_4667750_10	66373.JOFQ01000028_gene4345	7.958e-15	78.0	COG1131@1|root,COG1131@2|Bacteria,2GJ84@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990,ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC_tran
CMS1_k127_4669041_4	278957.ABEA03000202_gene4281	5.576e-24	102.0	COG0111@1|root,COG0111@2|Bacteria,46YD6@74201|Verrucomicrobia,3K9CB@414999|Opitutae	414999|Opitutae	EH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh_C
CMS1_k127_4669041_1	1499967.BAYZ01000145_gene6189	6.701e-115	374.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS1_k127_4669041_0	886293.Sinac_0734	2.083e-142	461.0	COG4225@1|root,COG4225@2|Bacteria,2IY9U@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Glycosyl Hydrolase Family 88	-	-	3.2.1.180	ko:K18581	-	-	R10867	RC00049,RC02427	ko00000,ko01000	-	GH88	-	Glyco_hydro_88
CMS1_k127_4669041_3	794903.OPIT5_16130	4.731e-90	303.0	COG1028@1|root,COG1028@2|Bacteria,46TD2@74201|Verrucomicrobia,3K7W5@414999|Opitutae	414999|Opitutae	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS1_k127_4669041_2	1187851.A33M_2010	2.809e-94	313.0	COG0800@1|root,COG0800@2|Bacteria,1MUVJ@1224|Proteobacteria,2TUMH@28211|Alphaproteobacteria,3FDIF@34008|Rhodovulum	28211|Alphaproteobacteria	G	KDPG and KHG aldolase	eda	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
CMS1_k127_4669041_5	926550.CLDAP_38290	2.69e-12	69.0	COG1977@1|root,COG1977@2|Bacteria,2G9DU@200795|Chloroflexi	200795|Chloroflexi	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
CMS1_k127_4675168_5	1122927.KB895414_gene5455	3.202e-18	86.0	COG2038@1|root,COG2038@2|Bacteria,1TPC1@1239|Firmicutes,4HAE0@91061|Bacilli,26RX1@186822|Paenibacillaceae	91061|Bacilli	H	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)	cobT	-	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	-	DBI_PRT
CMS1_k127_4675168_2	926550.CLDAP_27240	1.461e-75	265.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS1_k127_4675168_3	485916.Dtox_1386	1.941e-75	273.0	COG0863@1|root,COG1743@1|root,COG0863@2|Bacteria,COG1743@2|Bacteria,1TQWC@1239|Firmicutes,2492S@186801|Clostridia	186801|Clostridia	L	PFAM DNA methylase N-4 N-6	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase
CMS1_k127_4675168_4	1444309.JAQG01000181_gene3492	1.854e-32	133.0	COG3576@1|root,COG3576@2|Bacteria,1UZ02@1239|Firmicutes,4HEN8@91061|Bacilli,26R91@186822|Paenibacillaceae	91061|Bacilli	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
CMS1_k127_4675168_0	926569.ANT_00780	0.0	1114.0	COG3250@1|root,COG3250@2|Bacteria,2G61D@200795|Chloroflexi	200795|Chloroflexi	G	glycoside hydrolase family 2 immunoglobulin domain protein beta-sandwich	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
CMS1_k127_4675168_1	926569.ANT_16220	8.833e-160	512.0	COG0366@1|root,COG0366@2|Bacteria,2G7K6@200795|Chloroflexi	200795|Chloroflexi	G	SMART alpha amylase catalytic sub domain	-	-	3.2.1.1,3.2.1.20,5.4.99.16	ko:K01187,ko:K05343	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R01557,R02108,R02112,R06087,R06088,R11262	RC00028,RC00049,RC00077,RC01816	ko00000,ko00001,ko01000	-	GH13,GH31	-	Alpha-amylase,Malt_amylase_C
CMS1_k127_4676026_8	658086.HMPREF0994_03506	8.665e-06	53.0	COG2755@1|root,COG2755@2|Bacteria,1UIPA@1239|Firmicutes,25EQ0@186801|Clostridia	186801|Clostridia	E	Carbohydrate esterase, sialic acid-specific acetylesterase	-	-	-	-	-	-	-	-	-	-	-	-	SASA
CMS1_k127_4676026_7	1380350.JIAP01000003_gene4885	8.37e-11	68.0	COG0491@1|root,COG0491@2|Bacteria,1MY6G@1224|Proteobacteria,2TTBX@28211|Alphaproteobacteria,43JIG@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS1_k127_4676026_0	926569.ANT_10660	0.0	1030.0	COG0495@1|root,COG0495@2|Bacteria,2G5MX@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
CMS1_k127_4676026_4	357808.RoseRS_1962	4.465e-127	417.0	COG0115@1|root,COG0115@2|Bacteria,2G6AX@200795|Chloroflexi,3753Z@32061|Chloroflexia	32061|Chloroflexia	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
CMS1_k127_4676026_5	1173027.Mic7113_4388	9.793e-48	175.0	COG1403@1|root,COG1403@2|Bacteria,1G7ZB@1117|Cyanobacteria,1HC2V@1150|Oscillatoriales	1117|Cyanobacteria	L	PFAM HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH
CMS1_k127_4676026_6	118168.MC7420_3784	1.447e-25	112.0	2E16Z@1|root,32WMU@2|Bacteria,1G8XR@1117|Cyanobacteria,1HCB6@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4676026_1	926569.ANT_27120	1.478e-204	662.0	COG0574@1|root,COG0574@2|Bacteria	2|Bacteria	G	Belongs to the PEP-utilizing enzyme family	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PPDK_N
CMS1_k127_4676026_2	290317.Cpha266_0167	1.87e-181	576.0	COG0334@1|root,COG0334@2|Bacteria,1FE0H@1090|Chlorobi	1090|Chlorobi	C	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.3,1.4.1.4	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
CMS1_k127_4676026_3	289376.THEYE_A1151	1.98e-163	527.0	COG0064@1|root,COG0064@2|Bacteria,3J0FK@40117|Nitrospirae	40117|Nitrospirae	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
CMS1_k127_4677402_1	398527.Bphyt_5013	4.171e-203	643.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,2VZEK@28216|Betaproteobacteria,1K56M@119060|Burkholderiaceae	28216|Betaproteobacteria	J	tRNA synthetases class I (C) catalytic domain	-	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1e
CMS1_k127_4677402_3	1131462.DCF50_p77	1.366e-119	397.0	COG1055@1|root,COG1055@2|Bacteria,1TPNN@1239|Firmicutes,2494X@186801|Clostridia,261AN@186807|Peptococcaceae	186801|Clostridia	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
CMS1_k127_4677402_0	309807.SRU_2257	1.224e-211	680.0	COG0531@1|root,COG0531@2|Bacteria,4NFFX@976|Bacteroidetes,1FJSS@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease
CMS1_k127_4677402_2	1167006.UWK_00703	4.218e-164	535.0	COG0038@1|root,COG0517@1|root,COG0569@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,COG0569@2|Bacteria,1MV4K@1224|Proteobacteria,42N93@68525|delta/epsilon subdivisions,2WJ9N@28221|Deltaproteobacteria,2MHX8@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,TrkA_C,Voltage_CLC
CMS1_k127_4677682_3	1196323.ALKF01000199_gene2497	3.447e-81	276.0	COG3119@1|root,COG3119@2|Bacteria,1UDRD@1239|Firmicutes,4HD9J@91061|Bacilli,26R87@186822|Paenibacillaceae	91061|Bacilli	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CMS1_k127_4677682_1	266117.Rxyl_2349	1.272e-178	575.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria	201174|Actinobacteria	P	Pfam Sulfatase	atsG	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS1_k127_4677682_0	1121413.JMKT01000009_gene2096	9.069e-213	686.0	COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,42MR7@68525|delta/epsilon subdivisions,2WIKA@28221|Deltaproteobacteria,2M9JU@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	PFAM Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,Na_sulph_symp,TrkA_C
CMS1_k127_4677825_2	926569.ANT_22300	9.915e-28	129.0	COG3299@1|root,COG3299@2|Bacteria	2|Bacteria	S	Baseplate J-like protein	-	-	3.2.1.78	ko:K01218	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000	-	GH26	-	Baseplate_J,PA14,fn3
CMS1_k127_4677825_3	1499689.CCNN01000007_gene1624	6.43e-21	99.0	COG0816@1|root,COG0816@2|Bacteria,1V6ER@1239|Firmicutes,24JGP@186801|Clostridia,36IV4@31979|Clostridiaceae	186801|Clostridia	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	yrrK	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
CMS1_k127_4677825_0	926550.CLDAP_39240	1.681e-82	289.0	COG1559@1|root,COG1559@2|Bacteria,2G6G8@200795|Chloroflexi	200795|Chloroflexi	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
CMS1_k127_4677825_1	383372.Rcas_0801	1.043e-34	138.0	COG0438@1|root,COG0438@2|Bacteria,2G713@200795|Chloroflexi,37525@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glycos_transf_1
CMS1_k127_4678314_3	649638.Trad_2350	7.969e-16	80.0	COG1132@1|root,COG1132@2|Bacteria	2|Bacteria	V	(ABC) transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS1_k127_4678314_5	1122176.KB903619_gene5349	1.625e-09	70.0	COG1652@1|root,COG1652@2|Bacteria	2|Bacteria	S	positive regulation of growth rate	-	-	3.2.1.17	ko:K01185,ko:K02030,ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	M00236	-	-	ko00000,ko00001,ko00002,ko01000,ko02000,ko03019,ko03029,ko03110,ko04147	1.A.33.1,3.A.1.3	-	-	LysM,SBP_bac_3
CMS1_k127_4678314_0	1121380.JNIW01000002_gene2332	3.963e-81	287.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	SGL
CMS1_k127_4678314_2	929712.KI912613_gene2826	1.806e-29	122.0	COG1733@1|root,COG1733@2|Bacteria,2IM83@201174|Actinobacteria,4CQEM@84995|Rubrobacteria	84995|Rubrobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
CMS1_k127_4678314_1	926550.CLDAP_17320	2.649e-48	176.0	COG2259@1|root,COG2259@2|Bacteria	2|Bacteria	S	methylamine metabolic process	doxX	-	1.6.99.3	ko:K03885,ko:K15977	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	DoxX
CMS1_k127_4678314_4	1131462.DCF50_p850	7.144e-14	72.0	2E55P@1|root,32ZYJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4696208_0	867845.KI911784_gene1368	2.802e-151	493.0	COG1674@1|root,COG1674@2|Bacteria,2G5XC@200795|Chloroflexi,3753X@32061|Chloroflexia	32061|Chloroflexia	D	PFAM cell divisionFtsK SpoIIIE	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
CMS1_k127_4696208_3	926554.KI912674_gene2567	9.565e-32	139.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_4696208_1	479434.Sthe_1490	1.83e-138	458.0	COG0488@1|root,COG0488@2|Bacteria,2G5VD@200795|Chloroflexi,27XQY@189775|Thermomicrobia	200795|Chloroflexi	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
CMS1_k127_4696208_2	485913.Krac_11135	1.293e-51	192.0	COG4552@1|root,COG4552@2|Bacteria,2G7MV@200795|Chloroflexi	200795|Chloroflexi	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9
CMS1_k127_4697022_1	1501230.ET33_29385	7.477e-88	297.0	COG2159@1|root,COG2159@2|Bacteria,1TSSX@1239|Firmicutes,4IQZ6@91061|Bacilli,276K3@186822|Paenibacillaceae	91061|Bacilli	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
CMS1_k127_4697022_0	1123242.JH636434_gene4865	2.852e-99	336.0	COG4948@1|root,COG4948@2|Bacteria,2IYKA@203682|Planctomycetes	203682|Planctomycetes	M	Belongs to the mandelate racemase muconate lactonizing enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
CMS1_k127_4697022_3	926569.ANT_04400	3.913e-44	174.0	COG0454@1|root,COG1247@1|root,COG0456@2|Bacteria,COG1247@2|Bacteria,2G6N6@200795|Chloroflexi	200795|Chloroflexi	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS1_k127_4697022_8	118173.KB235914_gene2547	1.056e-13	72.0	COG1476@1|root,COG1476@2|Bacteria,1GFFE@1117|Cyanobacteria,1HG93@1150|Oscillatoriales	1117|Cyanobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
CMS1_k127_4697022_10	1089548.KI783301_gene1128	6.083e-08	65.0	COG3391@1|root,COG3391@2|Bacteria,1V255@1239|Firmicutes,4HFUF@91061|Bacilli	91061|Bacilli	M	40-residue YVTN family beta-propeller repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Collagen,Cytochrom_D1,Lactonase,Phosphoesterase
CMS1_k127_4697022_9	319795.Dgeo_2081	5.603e-09	70.0	COG1404@1|root,COG1404@2|Bacteria,1WKW6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	S53, subtilisin kexin sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
CMS1_k127_4697022_6	926550.CLDAP_09600	5.293e-21	109.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704	-	-	-	-	-	-	-	-	-	-	Collagen
CMS1_k127_4697022_4	1230457.C476_02062	2.494e-36	149.0	COG0616@1|root,arCOG01311@2157|Archaea,2XUZ2@28890|Euryarchaeota,23V1R@183963|Halobacteria	183963|Halobacteria	O	COG0616 Periplasmic serine proteases (ClpP class)	sppA2	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
CMS1_k127_4697022_7	926550.CLDAP_13230	2.322e-14	84.0	COG1840@1|root,COG1840@2|Bacteria	2|Bacteria	P	iron ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_11,SBP_bac_6
CMS1_k127_4697022_5	1173028.ANKO01000081_gene3815	6.087e-35	137.0	COG3809@1|root,COG3809@2|Bacteria,1G6XN@1117|Cyanobacteria,1HBMB@1150|Oscillatoriales	1117|Cyanobacteria	S	Transcription factor zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-TFIIB
CMS1_k127_4697022_2	1521187.JPIM01000023_gene785	7.862e-84	297.0	COG1840@1|root,COG2304@1|root,COG1840@2|Bacteria,COG2304@2|Bacteria,2G8ES@200795|Chloroflexi,3759V@32061|Chloroflexia	32061|Chloroflexia	P	PFAM von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	SBP_bac_11,VWA
CMS1_k127_4698540_5	926569.ANT_29190	6.244e-114	375.0	COG0697@1|root,COG0697@2|Bacteria,2G98J@200795|Chloroflexi	200795|Chloroflexi	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS1_k127_4698540_13	680198.SCAB_85771	6.964e-08	54.0	COG0667@1|root,COG0667@2|Bacteria,2GMNA@201174|Actinobacteria	201174|Actinobacteria	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS1_k127_4698540_1	1123276.KB893247_gene198	1.561e-240	752.0	COG2272@1|root,COG2272@2|Bacteria,4NG5B@976|Bacteroidetes,47UCC@768503|Cytophagia	976|Bacteroidetes	I	Carboxylesterase family	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
CMS1_k127_4698540_0	383372.Rcas_0921	1.181e-279	880.0	COG3408@1|root,COG3408@2|Bacteria	2|Bacteria	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
CMS1_k127_4698540_8	665942.HMPREF1022_02873	2.115e-92	307.0	COG0599@1|root,COG0599@2|Bacteria,1QTZH@1224|Proteobacteria,42TJW@68525|delta/epsilon subdivisions,2X9XM@28221|Deltaproteobacteria,2M9YY@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Carboxymuconolactone decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS1_k127_4698540_11	1536775.H70737_03205	5.784e-78	282.0	COG1472@1|root,COG1472@2|Bacteria,1TP63@1239|Firmicutes,4HBDB@91061|Bacilli,26TD5@186822|Paenibacillaceae	91061|Bacilli	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
CMS1_k127_4698540_2	485913.Krac_11430	1.854e-232	732.0	COG2936@1|root,COG2936@2|Bacteria,2G85Q@200795|Chloroflexi	2|Bacteria	S	PFAM X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
CMS1_k127_4698540_4	926569.ANT_29190	8.126e-126	409.0	COG0697@1|root,COG0697@2|Bacteria,2G98J@200795|Chloroflexi	200795|Chloroflexi	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS1_k127_4698540_6	28444.JODQ01000002_gene4637	2.228e-101	343.0	COG1063@1|root,COG1063@2|Bacteria,2GKC7@201174|Actinobacteria,4EPKW@85012|Streptosporangiales	201174|Actinobacteria	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_4698540_9	28444.JODQ01000002_gene4636	6.491e-92	309.0	COG1830@1|root,COG1830@2|Bacteria,2IB09@201174|Actinobacteria,4EKUU@85012|Streptosporangiales	201174|Actinobacteria	G	DeoC/LacD family aldolase	griI	-	2.3.1.245,4.1.2.13,4.1.2.56	ko:K08321,ko:K11645,ko:K18287	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko02024,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map02024	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
CMS1_k127_4698540_10	926569.ANT_24910	6.458e-90	316.0	COG1070@1|root,COG1070@2|Bacteria,2G5QX@200795|Chloroflexi	200795|Chloroflexi	G	PFAM carbohydrate kinase	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
CMS1_k127_4698540_7	28444.JODQ01000002_gene4635	1.404e-97	329.0	COG1063@1|root,COG1063@2|Bacteria,2GKC7@201174|Actinobacteria,4EPFQ@85012|Streptosporangiales	201174|Actinobacteria	E	Glucose dehydrogenase C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_4698540_3	525904.Tter_1881	3.602e-149	480.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_4698540_12	525904.Tter_1882	1.922e-57	214.0	COG0673@1|root,COG0673@2|Bacteria,2NRE6@2323|unclassified Bacteria	2|Bacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_4703141_2	926550.CLDAP_09690	8.252e-139	471.0	COG4485@1|root,COG4485@2|Bacteria,2G75F@200795|Chloroflexi	200795|Chloroflexi	S	Bacterial membrane protein YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
CMS1_k127_4703141_7	926550.CLDAP_09700	2.266e-38	161.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS1_k127_4703141_3	926550.CLDAP_09710	1.031e-79	273.0	COG1215@1|root,COG1215@2|Bacteria,2G6BS@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS1_k127_4703141_9	1329516.JPST01000023_gene2616	3.36e-32	136.0	COG0500@1|root,COG2226@2|Bacteria,1TSBS@1239|Firmicutes,4HMH8@91061|Bacilli	91061|Bacilli	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
CMS1_k127_4703141_1	1173024.KI912150_gene1283	8.489e-182	604.0	COG2374@1|root,COG2931@1|root,COG2374@2|Bacteria,COG2931@2|Bacteria,1GHDU@1117|Cyanobacteria,1JKFU@1189|Stigonemataceae	1117|Cyanobacteria	Q	Lamin Tail Domain	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Calx-beta,Exo_endo_phos,HemolysinCabind,LTD
CMS1_k127_4703141_0	56110.Oscil6304_5340	0.0	1212.0	COG1042@1|root,COG1670@1|root,COG1042@2|Bacteria,COG1670@2|Bacteria,1G2D3@1117|Cyanobacteria,1H81U@1150|Oscillatoriales	1117|Cyanobacteria	CJ	TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain	-	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
CMS1_k127_4703141_8	1121445.ATUZ01000011_gene329	1.411e-37	147.0	COG0517@1|root,COG0517@2|Bacteria,1RA25@1224|Proteobacteria,42R80@68525|delta/epsilon subdivisions,2WMW6@28221|Deltaproteobacteria,2MARF@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM CBS domain containing protein	-	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	CBS
CMS1_k127_4703141_4	926569.ANT_14300	9.825e-76	260.0	COG2197@1|root,COG2197@2|Bacteria,2G80G@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS1_k127_4703141_10	324602.Caur_0293	1.106e-29	135.0	COG0526@1|root,COG4243@1|root,COG0526@2|Bacteria,COG4243@2|Bacteria,2G9QC@200795|Chloroflexi,3764Y@32061|Chloroflexia	32061|Chloroflexia	CO	PFAM Vitamin K epoxide reductase	-	-	-	-	-	-	-	-	-	-	-	-	VKOR
CMS1_k127_4703141_6	1403819.BATR01000085_gene2460	1.419e-65	244.0	COG0785@1|root,COG0785@2|Bacteria	2|Bacteria	O	Cytochrome C biogenesis protein	-	-	-	-	-	-	-	-	-	-	-	-	DsbD,Glutaredoxin,SfLAP
CMS1_k127_4703141_5	1049564.TevJSym_ay00180	3.641e-75	278.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1S5BV@1236|Gammaproteobacteria,1J8NN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA,MASE1
CMS1_k127_4703141_11	204669.Acid345_1623	1.35e-14	73.0	COG0205@1|root,COG0205@2|Bacteria,3Y4A9@57723|Acidobacteria,2JKQ8@204432|Acidobacteriia	204432|Acidobacteriia	G	Phosphofructokinase	-	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
CMS1_k127_4712488_1	926569.ANT_03530	8.819e-186	609.0	COG0188@1|root,COG0188@2|Bacteria,2G5Q2@200795|Chloroflexi	200795|Chloroflexi	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
CMS1_k127_4712488_2	1449126.JQKL01000061_gene1910	6.936e-166	546.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,248AV@186801|Clostridia,2682S@186813|unclassified Clostridiales	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
CMS1_k127_4712488_0	324602.Caur_0868	2.284e-258	816.0	COG2217@1|root,COG2217@2|Bacteria,2G5QF@200795|Chloroflexi,376ZJ@32061|Chloroflexia	32061|Chloroflexia	P	TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,HMA,Hydrolase
CMS1_k127_4712488_3	1415780.JPOG01000001_gene3348	1.849e-16	89.0	COG0789@1|root,COG0789@2|Bacteria,1RGX6@1224|Proteobacteria,1SYIJ@1236|Gammaproteobacteria,1X7E5@135614|Xanthomonadales	135614|Xanthomonadales	K	helix_turn_helix, mercury resistance	-	-	-	ko:K19591	-	M00769	-	-	ko00000,ko00002,ko01504,ko03000	-	-	-	MerR,MerR-DNA-bind,MerR_1
CMS1_k127_4712488_4	1158345.JNLL01000001_gene619	1.047e-14	87.0	COG1752@1|root,COG1752@2|Bacteria,2G44Y@200783|Aquificae	200783|Aquificae	S	PFAM Patatin	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
CMS1_k127_4712488_5	984892.SPSE_1449	7.318e-11	72.0	COG1525@1|root,COG1525@2|Bacteria,1VASF@1239|Firmicutes,4HM0N@91061|Bacilli,4GZ2J@90964|Staphylococcaceae	91061|Bacilli	L	thermonuclease	nucI	-	3.1.31.1	ko:K01174	-	-	-	-	ko00000,ko01000	-	-	-	SNase
CMS1_k127_4712488_6	180332.JTGN01000025_gene1534	1.251e-07	53.0	COG3119@1|root,COG3119@2|Bacteria,1TSUU@1239|Firmicutes,25CDH@186801|Clostridia	186801|Clostridia	P	Psort location Cytoplasmic, score	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	DUF4976,Sulfatase
CMS1_k127_4713643_1	926550.CLDAP_10530	2.721e-37	159.0	COG0457@1|root,COG0823@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria,2G8PZ@200795|Chloroflexi	200795|Chloroflexi	U	WD40 domain protein beta Propeller	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
CMS1_k127_4713643_3	383372.Rcas_2068	1.648e-30	128.0	COG1595@1|root,COG1595@2|Bacteria,2G6T5@200795|Chloroflexi,375JF@32061|Chloroflexia	32061|Chloroflexia	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_4713643_0	479434.Sthe_2652	6.022e-148	479.0	COG0304@1|root,COG0304@2|Bacteria,2G5K7@200795|Chloroflexi,27Y13@189775|Thermomicrobia	189775|Thermomicrobia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
CMS1_k127_4713643_2	1094508.Tsac_2061	5.51e-31	126.0	COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,247P8@186801|Clostridia,42F9T@68295|Thermoanaerobacterales	186801|Clostridia	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
CMS1_k127_4727310_3	269799.Gmet_1782	4.124e-99	331.0	COG0861@1|root,COG0861@2|Bacteria,1MWC9@1224|Proteobacteria,42MZB@68525|delta/epsilon subdivisions,2WKV4@28221|Deltaproteobacteria,43TDE@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Integral membrane protein TerC family	-	-	-	-	-	-	-	-	-	-	-	-	TerC
CMS1_k127_4727310_9	309801.trd_0816	2.123e-37	146.0	COG3448@1|root,COG3448@2|Bacteria,2GBGW@200795|Chloroflexi	200795|Chloroflexi	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
CMS1_k127_4727310_8	937777.Deipe_1221	6.933e-38	148.0	COG1403@1|root,COG1403@2|Bacteria,1WICD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	PFAM HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
CMS1_k127_4727310_6	1122915.AUGY01000110_gene6806	1.696e-67	241.0	COG1082@1|root,COG1082@2|Bacteria,1VZJ0@1239|Firmicutes,4I7Y0@91061|Bacilli,26Y2S@186822|Paenibacillaceae	91061|Bacilli	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS1_k127_4727310_7	1267211.KI669560_gene610	1.73e-45	175.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS1_k127_4727310_0	1304880.JAGB01000002_gene2262	1.541e-172	547.0	COG0673@1|root,COG0673@2|Bacteria,1U4A4@1239|Firmicutes,249UF@186801|Clostridia	186801|Clostridia	E	PFAM oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_4727310_11	446470.Snas_6281	0.0006705	49.0	COG1175@1|root,COG1175@2|Bacteria,2GMV4@201174|Actinobacteria,4EZNC@85014|Glycomycetales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10241	ko02010,map02010	M00206	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.23	-	-	BPD_transp_1
CMS1_k127_4727310_2	926550.CLDAP_35620	1.623e-100	339.0	COG1175@1|root,COG1175@2|Bacteria	2|Bacteria	P	transmembrane transport	-	-	-	ko:K02025,ko:K05814,ko:K10118,ko:K10237,ko:K10241,ko:K15771,ko:K17235,ko:K17242,ko:K17316	ko02010,map02010	M00196,M00198,M00204,M00206,M00207,M00491,M00600,M00602,M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.17,3.A.1.1.2,3.A.1.1.23,3.A.1.1.24,3.A.1.1.28,3.A.1.1.3,3.A.1.1.30,3.A.1.1.34,3.A.1.1.39	-	-	BPD_transp_1
CMS1_k127_4727310_4	649638.Trad_2281	1.031e-84	289.0	COG0395@1|root,COG0395@2|Bacteria,1WJ2E@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	ABC-type sugar transport system, permease component	-	-	-	ko:K02026,ko:K05815	ko02010,map02010	M00198,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.3	-	-	BPD_transp_1
CMS1_k127_4727310_1	926550.CLDAP_35600	1.596e-133	443.0	COG1653@1|root,COG1653@2|Bacteria,2G8XC@200795|Chloroflexi	200795|Chloroflexi	G	COGs COG1653 ABC-type sugar transport system periplasmic component	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_8
CMS1_k127_4727310_5	926550.CLDAP_09650	8.903e-78	275.0	COG4907@1|root,COG4907@2|Bacteria	2|Bacteria	P	membrane protein (DUF2207)	yciQ	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF2207
CMS1_k127_4729022_3	1121405.dsmv_1613	5.742e-102	339.0	COG0618@1|root,COG0618@2|Bacteria,1N0JS@1224|Proteobacteria	1224|Proteobacteria	S	PFAM phosphoesterase, RecJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
CMS1_k127_4729022_1	1128421.JAGA01000002_gene468	1.782e-240	754.0	COG0504@1|root,COG0504@2|Bacteria,2NNVG@2323|unclassified Bacteria	2|Bacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1276,iECO103_1326.ECO103_3323,iHN637.CLJU_RS01075,iNJ661.Rv1699,iPC815.YPO3377	CTP_synth_N,GATase
CMS1_k127_4729022_6	926550.CLDAP_19750	5.772e-10	64.0	COG5012@1|root,COG5012@2|Bacteria	2|Bacteria	T	cobalamin binding	-	-	-	-	-	-	-	-	-	-	-	-	Virulence_fact
CMS1_k127_4729022_2	1120971.AUCA01000015_gene325	2.348e-103	347.0	COG0604@1|root,COG0604@2|Bacteria,1TPGA@1239|Firmicutes,4HBKZ@91061|Bacilli	91061|Bacilli	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	qor	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
CMS1_k127_4729022_0	1227352.C173_13242	2.26e-243	778.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,4HAAG@91061|Bacilli,26QA6@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the glycosyl hydrolase 3 family	-	-	3.2.1.21,3.2.1.52	ko:K01207,ko:K05349	ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501	M00628	R00022,R00026,R02558,R02887,R02985,R03527,R04949,R04998,R05963,R07809,R07810,R10035,R10039,R10040,R10831	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko00002,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
CMS1_k127_4729022_5	926550.CLDAP_24540	1.443e-52	194.0	COG2186@1|root,COG2186@2|Bacteria,2G8XU@200795|Chloroflexi	200795|Chloroflexi	K	FCD domain	-	-	-	-	-	-	-	-	-	-	-	-	FCD
CMS1_k127_4729022_4	1128421.JAGA01000003_gene2821	1.874e-73	254.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2NPPN@2323|unclassified Bacteria	2|Bacteria	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
CMS1_k127_473020_1	1382306.JNIM01000001_gene466	1.414e-108	361.0	COG1331@1|root,COG1331@2|Bacteria,2G5R1@200795|Chloroflexi	200795|Chloroflexi	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
CMS1_k127_473020_3	926550.CLDAP_27240	3.214e-63	228.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS1_k127_473020_4	391612.CY0110_12327	2.568e-56	206.0	COG2912@1|root,COG2912@2|Bacteria,1G11S@1117|Cyanobacteria,3KGMC@43988|Cyanothece	1117|Cyanobacteria	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	TPR_9,Transglut_core2
CMS1_k127_473020_2	383372.Rcas_3322	2.583e-67	236.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,2G6N4@200795|Chloroflexi,375K6@32061|Chloroflexia	32061|Chloroflexia	K	iron dependent repressor	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
CMS1_k127_473020_6	3649.evm.model.supercontig_5.125	6.227e-25	111.0	KOG0568@1|root,KOG0568@2759|Eukaryota,37PDH@33090|Viridiplantae,3GEYN@35493|Streptophyta,3HVVH@3699|Brassicales	35493|Streptophyta	O	Domain of unknown function (DUF1992)	-	-	-	ko:K19373	-	-	-	-	ko00000,ko03110	-	-	-	DUF1992
CMS1_k127_473020_0	1191523.MROS_0178	1.234e-241	752.0	COG0114@1|root,COG0114@2|Bacteria	2|Bacteria	C	fumarate hydratase activity	fumC	GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
CMS1_k127_473020_7	760568.Desku_1972	4.965e-07	54.0	COG4636@1|root,COG4636@2|Bacteria	2|Bacteria	D	protein conserved in cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
CMS1_k127_473020_5	1521187.JPIM01000023_gene785	5.066e-35	142.0	COG1840@1|root,COG2304@1|root,COG1840@2|Bacteria,COG2304@2|Bacteria,2G8ES@200795|Chloroflexi,3759V@32061|Chloroflexia	32061|Chloroflexia	P	PFAM von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	SBP_bac_11,VWA
CMS1_k127_4730464_7	472759.Nhal_1492	6.295e-29	121.0	COG1262@1|root,COG1672@1|root,COG1262@2|Bacteria,COG1672@2|Bacteria,1RAMU@1224|Proteobacteria,1S87Q@1236|Gammaproteobacteria,1X2AR@135613|Chromatiales	135613|Chromatiales	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
CMS1_k127_4730464_8	649639.Bcell_0867	2.433e-14	76.0	COG1476@1|root,COG1476@2|Bacteria,1VCMF@1239|Firmicutes,4HQAM@91061|Bacilli,1ZJDE@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
CMS1_k127_4730464_10	991905.SL003B_1086	3.697e-06	53.0	2EFRX@1|root,339HW@2|Bacteria,1NEME@1224|Proteobacteria,2UFXW@28211|Alphaproteobacteria,4BSX5@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4730464_5	926569.ANT_28790	1.409e-50	182.0	COG1545@1|root,COG1545@2|Bacteria,2G73Z@200795|Chloroflexi	200795|Chloroflexi	S	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
CMS1_k127_4730464_3	926550.CLDAP_27990	1.498e-149	483.0	COG0183@1|root,COG0183@2|Bacteria,2G63J@200795|Chloroflexi	200795|Chloroflexi	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
CMS1_k127_4730464_2	926569.ANT_28810	1.156e-150	483.0	COG3425@1|root,COG3425@2|Bacteria,2G606@200795|Chloroflexi	200795|Chloroflexi	I	3-Oxoacyl- acyl-carrier-protein (ACP) synthase III domain protein	-	-	2.3.3.10	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	M00088,M00095	R01978	RC00004,RC00503	ko00000,ko00001,ko00002,ko01000	-	-	-	ACP_syn_III_C
CMS1_k127_4730464_1	926550.CLDAP_37800	6.308e-159	511.0	COG1257@1|root,COG1257@2|Bacteria,2G5QV@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the HMG-CoA reductase family	mvaA	-	1.1.1.88	ko:K00054	ko00900,ko01110,ko01130,map00900,map01110,map01130	-	R02081	RC00004,RC00644	ko00000,ko00001,ko01000	-	-	-	HMG-CoA_red
CMS1_k127_4730464_4	926550.CLDAP_36690	2.486e-127	417.0	COG3876@1|root,COG3876@2|Bacteria,2G655@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF1343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
CMS1_k127_4730464_0	926569.ANT_12970	1.146e-160	524.0	COG0323@1|root,COG0323@2|Bacteria,2G5XU@200795|Chloroflexi	200795|Chloroflexi	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
CMS1_k127_4730464_6	309801.trd_0439	2.914e-29	127.0	COG0204@1|root,COG0204@2|Bacteria,2G78P@200795|Chloroflexi,27Y83@189775|Thermomicrobia	189775|Thermomicrobia	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
CMS1_k127_4730464_9	626887.J057_19075	1.587e-10	63.0	COG0695@1|root,COG0695@2|Bacteria,1NH8Z@1224|Proteobacteria,1SGAT@1236|Gammaproteobacteria,46903@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	COG0526 Thiol-disulfide isomerase and thioredoxins	XAC3035	-	-	-	-	-	-	-	-	-	-	-	DUF836
CMS1_k127_4731178_3	1121335.Clst_0017	1.418e-39	151.0	COG0432@1|root,COG0432@2|Bacteria,1V6J7@1239|Firmicutes,24J8G@186801|Clostridia,3WIZN@541000|Ruminococcaceae	186801|Clostridia	S	Secondary thiamine-phosphate synthase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
CMS1_k127_4731178_0	926550.CLDAP_22040	8.263e-140	467.0	COG0358@1|root,COG0358@2|Bacteria,2G65X@200795|Chloroflexi	200795|Chloroflexi	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
CMS1_k127_4731178_1	926550.CLDAP_22030	3.209e-126	416.0	COG0568@1|root,COG0568@2|Bacteria,2G5W3@200795|Chloroflexi	200795|Chloroflexi	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
CMS1_k127_4731178_2	926550.CLDAP_14450	2.845e-47	179.0	COG3815@1|root,COG3815@2|Bacteria	2|Bacteria	S	Predicted membrane protein (DUF2085)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2085
CMS1_k127_4741850_4	298654.FraEuI1c_1520	8.353e-35	141.0	COG1228@1|root,COG1228@2|Bacteria,2GMUS@201174|Actinobacteria,4ETZT@85013|Frankiales	201174|Actinobacteria	Q	PFAM amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
CMS1_k127_4741850_5	1347086.CCBA010000022_gene2949	3.334e-24	117.0	COG0477@1|root,COG2814@2|Bacteria,1TS1D@1239|Firmicutes,4HCUB@91061|Bacilli,1ZBCP@1386|Bacillus	91061|Bacilli	EGP	MFS_1 like family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like
CMS1_k127_4741850_3	1122611.KB903985_gene3897	4.534e-45	173.0	COG1028@1|root,COG1028@2|Bacteria,2IAJK@201174|Actinobacteria,4EMQJ@85012|Streptosporangiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.127	ko:K00065	ko00040,map00040	-	R01542	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
CMS1_k127_4741850_1	1303518.CCALI_00161	5.898e-85	289.0	COG3622@1|root,COG3622@2|Bacteria	2|Bacteria	G	hydroxypyruvate isomerase activity	gip	-	5.3.1.22	ko:K01816	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
CMS1_k127_4741850_2	1380394.JADL01000002_gene1318	4.999e-82	287.0	COG2141@1|root,COG2141@2|Bacteria,1MX64@1224|Proteobacteria,2TT8C@28211|Alphaproteobacteria,2JW97@204441|Rhodospirillales	204441|Rhodospirillales	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS1_k127_4741850_0	1120950.KB892765_gene5704	7.991e-166	535.0	COG3119@1|root,COG3119@2|Bacteria,2IK10@201174|Actinobacteria	201174|Actinobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS1_k127_4742604_3	1120950.KB892746_gene3548	5.193e-117	381.0	COG4948@1|root,COG4948@2|Bacteria,2IA82@201174|Actinobacteria	201174|Actinobacteria	M	Mandelate racemase / muconate lactonizing enzyme, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
CMS1_k127_4742604_0	649638.Trad_2420	1.44e-245	767.0	COG0405@1|root,COG0405@2|Bacteria,1WI9V@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	PFAM Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
CMS1_k127_4742604_6	313603.FB2170_04525	5.538e-92	310.0	COG0684@1|root,COG0684@2|Bacteria,4NF3M@976|Bacteroidetes,1HZ8J@117743|Flavobacteriia,2PHRX@252356|Maribacter	976|Bacteroidetes	H	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
CMS1_k127_4742604_1	1122605.KB893625_gene1882	2.498e-240	771.0	COG4354@1|root,COG4354@2|Bacteria,4NFQW@976|Bacteroidetes,1IR0K@117747|Sphingobacteriia	976|Bacteroidetes	G	beta-glucosidase 2, glycosyl-hydrolase family 116 N-term	-	-	3.2.1.45	ko:K17108	ko00511,ko00600,ko01100,map00511,map00600,map01100	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH116	-	DUF608,Glyco_hydr_116N
CMS1_k127_4742604_16	386456.JQKN01000001_gene2066	5.018e-43	169.0	COG1208@1|root,arCOG00666@2157|Archaea,2XT8U@28890|Euryarchaeota,23NRH@183925|Methanobacteria	183925|Methanobacteria	M	Bacterial transferase hexapeptide repeat	-	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
CMS1_k127_4742604_21	926550.CLDAP_04900	4.538e-09	68.0	COG3391@1|root,COG4447@1|root,COG3391@2|Bacteria,COG4447@2|Bacteria,2G9C0@200795|Chloroflexi	200795|Chloroflexi	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4742604_18	1198114.AciX9_2489	1.346e-30	132.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	wcoG	-	-	-	-	-	-	-	-	-	-	-	DUF5122,Laminin_G_3,PKD
CMS1_k127_4742604_4	926569.ANT_16070	6.793e-98	331.0	COG0006@1|root,COG0006@2|Bacteria,2G6AH@200795|Chloroflexi	200795|Chloroflexi	E	peptidase M24	-	-	3.4.13.9	ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Creatinase_N,Peptidase_M24
CMS1_k127_4742604_10	696281.Desru_0856	1.768e-68	245.0	COG0715@1|root,COG0715@2|Bacteria,1UW7X@1239|Firmicutes,25M8F@186801|Clostridia,266N3@186807|Peptococcaceae	186801|Clostridia	P	NMT1/THI5 like	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
CMS1_k127_4742604_9	1444306.JFZC01000041_gene74	1.909e-73	256.0	COG0600@1|root,COG0600@2|Bacteria,1UYCY@1239|Firmicutes,4HFWQ@91061|Bacilli,26Q0K@186821|Sporolactobacillaceae	91061|Bacilli	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
CMS1_k127_4742604_12	1304877.KI519400_gene607	6.476e-67	237.0	COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,2TSH9@28211|Alphaproteobacteria,3JQW2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	ABC transporter	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
CMS1_k127_4742604_8	1128421.JAGA01000002_gene1263	1.111e-76	261.0	COG1335@1|root,COG1335@2|Bacteria,2NRUW@2323|unclassified Bacteria	2|Bacteria	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
CMS1_k127_4742604_13	324602.Caur_2456	1.188e-64	231.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
CMS1_k127_4742604_15	926569.ANT_15020	5.509e-60	224.0	COG0477@1|root,COG2814@2|Bacteria,2G71K@200795|Chloroflexi	200795|Chloroflexi	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_4742604_17	316274.Haur_1219	3.372e-34	135.0	COG0784@1|root,COG0784@2|Bacteria,2GA6X@200795|Chloroflexi,375DW@32061|Chloroflexia	2|Bacteria	T	PFAM response regulator receiver	-	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
CMS1_k127_4742604_19	483215.BACFIN_06821	6.138e-16	92.0	COG0642@1|root,COG2199@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria,4NGZ0@976|Bacteroidetes,2FNI2@200643|Bacteroidia,4ANTW@815|Bacteroidaceae	976|Bacteroidetes	T	Response regulator receiver domain protein	pleD	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Response_reg
CMS1_k127_4742604_2	926569.ANT_11770	1.034e-168	553.0	COG0498@1|root,COG0784@1|root,COG0498@2|Bacteria,COG0784@2|Bacteria,2G5RK@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS1_k127_4742604_7	926569.ANT_11780	2.396e-82	306.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG2203@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,2G84W@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
CMS1_k127_4742604_14	439235.Dalk_3399	3.45e-64	232.0	COG0715@1|root,COG0715@2|Bacteria,1QVUU@1224|Proteobacteria,43CS5@68525|delta/epsilon subdivisions,2X5E2@28221|Deltaproteobacteria,2MQ33@213118|Desulfobacterales	28221|Deltaproteobacteria	P	NMT1/THI5 like	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
CMS1_k127_4742604_20	1267534.KB906755_gene3968	1.176e-10	74.0	COG1956@1|root,COG2203@1|root,COG2208@1|root,COG1956@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,3Y358@57723|Acidobacteria,2JIID@204432|Acidobacteriia	204432|Acidobacteriia	T	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_2,SpoIIE
CMS1_k127_4742604_5	316274.Haur_1217	8.543e-98	353.0	COG0642@1|root,COG2202@1|root,COG3290@1|root,COG3829@1|root,COG3850@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3290@2|Bacteria,COG3829@2|Bacteria,COG3850@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.7.13.3,4.6.1.1	ko:K01768,ko:K11527,ko:K18143	ko00230,ko01501,ko02025,ko04113,ko04213,map00230,map01501,map02025,map04113,map04213	M00649,M00655,M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	CHASE,GAF,GGDEF,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
CMS1_k127_4742604_11	756067.MicvaDRAFT_3601	1.094e-67	262.0	COG0840@1|root,COG2202@1|root,COG3829@1|root,COG4191@1|root,COG0840@2|Bacteria,COG2202@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1GBFY@1117|Cyanobacteria,1HE1Q@1150|Oscillatoriales	1117|Cyanobacteria	T	Methyl-accepting chemotaxis sensory transducer with Pas Pac sensor	-	-	-	ko:K02660	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	MCPsignal,PAS_3,PAS_4,PAS_8,PAS_9
CMS1_k127_4742749_1	926550.CLDAP_13670	9.475e-83	280.0	COG1070@1|root,COG1070@2|Bacteria,2G7KS@200795|Chloroflexi	200795|Chloroflexi	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
CMS1_k127_4742749_2	1173026.Glo7428_1028	9.322e-70	241.0	COG0454@1|root,COG0456@2|Bacteria,1G5CH@1117|Cyanobacteria	1117|Cyanobacteria	K	PFAM Acetyltransferase (GNAT) family	-	-	2.3.1.82	ko:K18815	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	Acetyltransf_1
CMS1_k127_4742749_8	589865.DaAHT2_0985	5.872e-25	119.0	COG1051@1|root,COG1051@2|Bacteria,1Q6B8@1224|Proteobacteria,432SA@68525|delta/epsilon subdivisions,2WXPX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	NUDIX domain	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
CMS1_k127_4742749_10	1173026.Glo7428_1028	6.324e-18	86.0	COG0454@1|root,COG0456@2|Bacteria,1G5CH@1117|Cyanobacteria	1117|Cyanobacteria	K	PFAM Acetyltransferase (GNAT) family	-	-	2.3.1.82	ko:K18815	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	Acetyltransf_1
CMS1_k127_4742749_3	316274.Haur_4550	2.54e-59	211.0	COG4552@1|root,COG4552@2|Bacteria,2GAIZ@200795|Chloroflexi,376FX@32061|Chloroflexia	32061|Chloroflexia	S	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9
CMS1_k127_4742749_7	1206733.BAGC01000040_gene1764	1.686e-25	110.0	2E8H6@1|root,332VD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
CMS1_k127_4742749_0	373903.Hore_09710	2.519e-126	411.0	COG0524@1|root,COG0524@2|Bacteria,1TRRQ@1239|Firmicutes,258PD@186801|Clostridia,3WC27@53433|Halanaerobiales	186801|Clostridia	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
CMS1_k127_4742749_4	324602.Caur_2225	4.214e-53	213.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2G790@200795|Chloroflexi,3750C@32061|Chloroflexia	32061|Chloroflexia	T	SMART protein phosphatase 2C domain protein	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_2,GAF_3,SpoIIE
CMS1_k127_4742749_5	926550.CLDAP_32480	1.436e-34	153.0	COG1807@1|root,COG1807@2|Bacteria	926550.CLDAP_32480|-	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4742749_6	926550.CLDAP_32480	9.156e-34	150.0	COG1807@1|root,COG1807@2|Bacteria	926550.CLDAP_32480|-	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4747088_3	661478.OP10G_0033	3.351e-23	109.0	2F765@1|root,2ZKNT@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4747088_1	1459636.NTE_01256	2.601e-42	167.0	COG1478@1|root,arCOG02714@2157|Archaea,41SHA@651137|Thaumarchaeota	651137|Thaumarchaeota	H	F420-0:Gamma-glutamyl ligase	-	-	-	-	-	-	-	-	-	-	-	-	F420_ligase
CMS1_k127_4747088_2	1210884.HG799463_gene9610	7.935e-35	138.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS1_k127_4747088_0	335543.Sfum_3416	1.324e-58	208.0	COG0596@1|root,COG0596@2|Bacteria,1NEZY@1224|Proteobacteria,42WGF@68525|delta/epsilon subdivisions,2WSB8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4751589_7	926550.CLDAP_32820	9.569e-48	187.0	COG3307@1|root,COG3307@2|Bacteria,2G79D@200795|Chloroflexi	200795|Chloroflexi	M	O-Antigen ligase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
CMS1_k127_4751589_10	1382356.JQMP01000003_gene2407	5.04e-08	63.0	2ETJ3@1|root,33M2W@2|Bacteria,2G7IK@200795|Chloroflexi,27YKN@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4751589_5	649638.Trad_0975	1.404e-96	322.0	COG0410@1|root,COG0410@2|Bacteria,1WJM5@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	ABC-type branched-chain amino acid transport systems ATPase component	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
CMS1_k127_4751589_4	1122138.AQUZ01000019_gene8164	4.816e-102	338.0	COG0411@1|root,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria,4DPPJ@85009|Propionibacteriales	201174|Actinobacteria	E	Amino acid amide ABC transporter ATP-binding protein 1, HAAT family	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
CMS1_k127_4751589_1	1122138.AQUZ01000019_gene8165	1.87e-119	409.0	COG4177@1|root,COG4177@2|Bacteria,2I8MK@201174|Actinobacteria,4DRJH@85009|Propionibacteriales	201174|Actinobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
CMS1_k127_4751589_2	1128421.JAGA01000002_gene1295	1.989e-119	393.0	COG0559@1|root,COG0559@2|Bacteria,2NP7Z@2323|unclassified Bacteria	2|Bacteria	E	Branched-chain amino acid transport system / permease component	livH	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
CMS1_k127_4751589_3	309801.trd_A0634	7.315e-110	373.0	COG0683@1|root,COG0683@2|Bacteria,2G7TX@200795|Chloroflexi,27YY0@189775|Thermomicrobia	189775|Thermomicrobia	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
CMS1_k127_4751589_9	697282.Mettu_2817	2.655e-14	87.0	COG0715@1|root,COG4191@1|root,COG0715@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RR5W@1236|Gammaproteobacteria,1XE73@135618|Methylococcales	135618|Methylococcales	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_9
CMS1_k127_4751589_8	1396141.BATP01000005_gene5985	3.362e-16	90.0	COG2319@1|root,COG2319@2|Bacteria,46UIQ@74201|Verrucomicrobia,2IV42@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1,WD40
CMS1_k127_4751589_12	626887.J057_16620	0.0001577	53.0	2EJZ3@1|root,33DPP@2|Bacteria,1NKIC@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4751589_0	1128421.JAGA01000003_gene2874	2.239e-123	407.0	COG4531@1|root,COG4531@2|Bacteria,2NP5Y@2323|unclassified Bacteria	2|Bacteria	P	ABC-type Zn2 transport system, periplasmic component surface adhesin	actF	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4751589_6	1128421.JAGA01000003_gene2873	8.845e-54	195.0	COG2010@1|root,COG2010@2|Bacteria,2NPQJ@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	actE	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CMS1_k127_4751589_11	941770.GL622182_gene1303	1.604e-06	55.0	COG1418@1|root,COG1418@2|Bacteria,1V7IZ@1239|Firmicutes,4HIVB@91061|Bacilli,3F3PN@33958|Lactobacillaceae	91061|Bacilli	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	yagB	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
CMS1_k127_4759738_3	926550.CLDAP_03810	6.778e-62	222.0	COG0101@1|root,COG0101@2|Bacteria,2G6PE@200795|Chloroflexi	200795|Chloroflexi	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
CMS1_k127_4759738_6	697303.Thewi_2226	9.16e-40	150.0	COG0203@1|root,COG0203@2|Bacteria,1V6JQ@1239|Firmicutes,24J9T@186801|Clostridia,42GJW@68295|Thermoanaerobacterales	186801|Clostridia	J	ribosomal protein l17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
CMS1_k127_4759738_1	926550.CLDAP_03830	2.242e-130	424.0	COG0202@1|root,COG0202@2|Bacteria,2G5M9@200795|Chloroflexi	200795|Chloroflexi	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
CMS1_k127_4759738_2	264732.Moth_2432	3.133e-77	263.0	COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,248Y5@186801|Clostridia,42ENH@68295|Thermoanaerobacterales	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
CMS1_k127_4759738_4	1382356.JQMP01000003_gene2286	1.343e-52	188.0	COG0100@1|root,COG0100@2|Bacteria,2G6HG@200795|Chloroflexi,27YAA@189775|Thermomicrobia	189775|Thermomicrobia	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
CMS1_k127_4759738_5	485913.Krac_12504	1.992e-49	178.0	COG0099@1|root,COG0099@2|Bacteria,2G6PF@200795|Chloroflexi	200795|Chloroflexi	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
CMS1_k127_4759738_7	760154.Sulba_2061	3.901e-14	72.0	COG0257@1|root,COG0257@2|Bacteria,1NGEI@1224|Proteobacteria,42WXD@68525|delta/epsilon subdivisions,2YQQ9@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
CMS1_k127_4759738_0	525904.Tter_0735	2.12e-140	458.0	COG0201@1|root,COG0201@2|Bacteria,2NNVK@2323|unclassified Bacteria	2|Bacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
CMS1_k127_4774517_1	671143.DAMO_2439	6.21e-21	99.0	COG2197@1|root,COG2202@1|root,COG2197@2|Bacteria,COG2202@2|Bacteria	2|Bacteria	T	Pas domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF_2,GGDEF,GerE,HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,Response_reg
CMS1_k127_4774517_0	1121007.AUML01000002_gene1598	3.157e-210	667.0	COG1018@1|root,COG1020@1|root,COG1018@2|Bacteria,COG1020@2|Bacteria,4P29Y@976|Bacteroidetes,1I7GR@117743|Flavobacteriia,2YI39@290174|Aquimarina	976|Bacteroidetes	CQ	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
CMS1_k127_47750_1	383372.Rcas_3060	9.322e-40	160.0	COG1277@1|root,COG1277@2|Bacteria,2GBME@200795|Chloroflexi,3782B@32061|Chloroflexia	32061|Chloroflexia	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_47750_0	326427.Cagg_1671	1.37e-68	239.0	COG1131@1|root,COG1131@2|Bacteria,2GAQH@200795|Chloroflexi,3753M@32061|Chloroflexia	32061|Chloroflexia	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
CMS1_k127_4779806_7	1356854.N007_02060	3.638e-40	153.0	COG0684@1|root,COG0684@2|Bacteria,1V1ME@1239|Firmicutes,4HGQE@91061|Bacilli,27ARM@186823|Alicyclobacillaceae	91061|Bacilli	H	Aldolase/RraA	-	-	4.1.3.17	ko:K10218	ko00362,ko00660,ko01120,map00362,map00660,map01120	-	R00008,R00350	RC00067,RC00502,RC01205	ko00000,ko00001,ko01000	-	-	-	RraA-like
CMS1_k127_4779806_0	926550.CLDAP_27060	0.0	2006.0	COG0366@1|root,COG4733@1|root,COG0366@2|Bacteria,COG4733@2|Bacteria,2G7WY@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the glycosyl hydrolase 13 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,CBM_20,fn3
CMS1_k127_4779806_15	1121405.dsmv_2300	3.336e-13	70.0	2EFZF@1|root,339RM@2|Bacteria,1NH6S@1224|Proteobacteria,42WYZ@68525|delta/epsilon subdivisions,2WT48@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4779806_11	941449.dsx2_0361	2.369e-14	74.0	2E4YG@1|root,32ZSB@2|Bacteria,1N74T@1224|Proteobacteria,42XBI@68525|delta/epsilon subdivisions,2WSNB@28221|Deltaproteobacteria,2MD29@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3309)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3309
CMS1_k127_4779806_9	1569209.BBPH01000022_gene350	6.109e-21	94.0	COG3237@1|root,COG3237@2|Bacteria,1N6X4@1224|Proteobacteria,2UF5Q@28211|Alphaproteobacteria,2PXST@265|Paracoccus	28211|Alphaproteobacteria	S	CsbD-like	csbD	-	-	-	-	-	-	-	-	-	-	-	CsbD
CMS1_k127_4779806_14	102129.Lepto7375DRAFT_7320	2.423e-13	76.0	COG2389@1|root,COG2389@2|Bacteria,1G6XV@1117|Cyanobacteria,1HAKZ@1150|Oscillatoriales	1117|Cyanobacteria	S	metal-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2227
CMS1_k127_4779806_17	1079986.JH164838_gene4242	8.915e-10	68.0	COG4454@1|root,COG4454@2|Bacteria,2GS6Z@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
CMS1_k127_4779806_1	247490.KSU1_C1040	0.0	1108.0	COG0474@1|root,COG0474@2|Bacteria,2IXV7@203682|Planctomycetes	203682|Planctomycetes	P	TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.2	ko:K01531	-	-	-	-	ko00000,ko01000	3.A.3.4	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,SBP_bac_1
CMS1_k127_4779806_3	1173028.ANKO01000174_gene2700	2.395e-155	502.0	COG4325@1|root,COG4325@2|Bacteria,1G2Y0@1117|Cyanobacteria,1H8XM@1150|Oscillatoriales	1117|Cyanobacteria	S	membrane protein (DUF2254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2254
CMS1_k127_4779806_5	927677.ALVU02000001_gene922	1.135e-82	282.0	2DBB1@1|root,2Z854@2|Bacteria,1G05N@1117|Cyanobacteria	1117|Cyanobacteria	S	Domain of Unknown Function (DUF1206)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1206
CMS1_k127_4779806_10	204669.Acid345_3970	3.778e-20	96.0	2DQJB@1|root,3377V@2|Bacteria,3Y8JD@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4779806_6	702113.PP1Y_AT34256	4.973e-46	173.0	2ADQJ@1|root,313FX@2|Bacteria,1MYNR@1224|Proteobacteria,2UCQS@28211|Alphaproteobacteria,2K5ZN@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4779806_16	1121921.KB898706_gene2834	3.237e-11	64.0	COG5487@1|root,COG5487@2|Bacteria	2|Bacteria	S	UPF0391 membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1328
CMS1_k127_4779806_12	690850.Desaf_2012	7.886e-14	72.0	COG5487@1|root,COG5487@2|Bacteria,1NGAH@1224|Proteobacteria,436FM@68525|delta/epsilon subdivisions,2X115@28221|Deltaproteobacteria,2MDZC@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	UPF0391 membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1328
CMS1_k127_4779806_4	1519464.HY22_07245	2.736e-103	347.0	COG4783@1|root,COG4783@2|Bacteria,1FFG5@1090|Chlorobi	1090|Chlorobi	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
CMS1_k127_4779806_18	316274.Haur_2800	3.599e-06	53.0	COG0628@1|root,COG0628@2|Bacteria	2|Bacteria	D	permease	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
CMS1_k127_4779806_8	479434.Sthe_0419	1.888e-21	97.0	COG0842@1|root,COG0842@2|Bacteria,2G8I5@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
CMS1_k127_4779806_2	1499967.BAYZ01000058_gene4744	1.751e-217	679.0	COG0673@1|root,COG0673@2|Bacteria,2NRVS@2323|unclassified Bacteria	2|Bacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_4791621_2	926550.CLDAP_32470	1.014e-15	83.0	COG1807@1|root,COG1807@2|Bacteria,2G8DG@200795|Chloroflexi	200795|Chloroflexi	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS1_k127_4791621_1	1128421.JAGA01000002_gene78	1.658e-21	111.0	COG1928@1|root,COG1928@2|Bacteria	2|Bacteria	O	C-terminal four TMM region of protein-O-mannosyltransferase	-	-	2.4.1.109	ko:K00728	ko00514,ko00515,ko01100,map00514,map00515,map01100	-	R04072,R07620,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003	-	GT39	-	PMT,PMT_2,PMT_4TMC
CMS1_k127_4791621_0	926550.CLDAP_32470	4.583e-23	117.0	COG1807@1|root,COG1807@2|Bacteria,2G8DG@200795|Chloroflexi	200795|Chloroflexi	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS1_k127_4791621_3	469383.Cwoe_5488	0.0005507	51.0	COG1807@1|root,COG1807@2|Bacteria,2GVIK@201174|Actinobacteria,4CQCI@84995|Rubrobacteria	84995|Rubrobacteria	M	Predicted membrane protein (DUF2142)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2142
CMS1_k127_4794160_0	933262.AXAM01000171_gene929	2.958e-31	126.0	2DYI2@1|root,349W0@2|Bacteria,1NZTD@1224|Proteobacteria,431EW@68525|delta/epsilon subdivisions,2WWNI@28221|Deltaproteobacteria,2MNU2@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4794160_3	345341.KUTG_07608	0.0002091	50.0	COG3903@1|root,COG3903@2|Bacteria,2GIRS@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator, SARP family	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,NB-ARC,TPR_12,Trans_reg_C
CMS1_k127_4794160_1	326427.Cagg_1682	2.166e-23	103.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	MA20_23570	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_34
CMS1_k127_480584_2	926569.ANT_25740	4.369e-29	133.0	COG0863@1|root,COG0863@2|Bacteria	2|Bacteria	L	N-4 methylation of cytosine	-	-	2.1.1.113	ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	-
CMS1_k127_480584_0	429009.Adeg_1192	4.536e-142	458.0	COG1064@1|root,COG1064@2|Bacteria,1TP5B@1239|Firmicutes,24GKF@186801|Clostridia,42HT2@68295|Thermoanaerobacterales	186801|Clostridia	C	TIGRFAM zinc-binding alcohol dehydrogenase family protein	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_480584_3	316274.Haur_3749	7.333e-27	119.0	COG1994@1|root,COG1994@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50B
CMS1_k127_480584_1	926550.CLDAP_22220	2.333e-141	469.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2G5J0@200795|Chloroflexi	200795|Chloroflexi	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
CMS1_k127_4808213_5	926569.ANT_26580	6.248e-13	72.0	COG3462@1|root,COG3462@2|Bacteria	2|Bacteria	S	membrane protein (DUF2078)	-	-	-	ko:K08982	-	-	-	-	ko00000	-	-	-	SHOCT
CMS1_k127_4808213_3	2002.JOEQ01000022_gene6889	6.34e-17	82.0	COG2197@1|root,COG2197@2|Bacteria,2GKBX@201174|Actinobacteria,4EN6R@85012|Streptosporangiales	201174|Actinobacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS1_k127_4808213_4	408672.NBCG_03850	1.148e-13	78.0	2E5KE@1|root,330BK@2|Bacteria,2IKV9@201174|Actinobacteria,4DSID@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4808213_6	383372.Rcas_3701	6.612e-05	46.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GAAG@200795|Chloroflexi,374S4@32061|Chloroflexia	32061|Chloroflexia	K	transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,TPR_12,Trans_reg_C
CMS1_k127_4808213_1	926569.ANT_30210	4.893e-96	331.0	COG4585@1|root,COG4585@2|Bacteria	2|Bacteria	T	Histidine kinase	salK	-	2.7.13.3	ko:K07680,ko:K07778,ko:K11617,ko:K14988	ko02020,ko02024,map02020,map02024	M00476,M00479,M00481,M00522,M00754	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3
CMS1_k127_4808213_2	926569.ANT_30220	1.101e-71	249.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	devR	GO:0001666,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005576,GO:0005615,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006950,GO:0008150,GO:0009405,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010565,GO:0010604,GO:0010628,GO:0016020,GO:0018995,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0022611,GO:0030312,GO:0030430,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032502,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0036293,GO:0043656,GO:0043657,GO:0044174,GO:0044215,GO:0044216,GO:0044217,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0070482,GO:0071944,GO:0072493,GO:0080090,GO:0080134,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1902882,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K02479,ko:K07695	ko02020,map02020	M00482	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
CMS1_k127_4808213_0	1236976.JCM16418_1289	8.693e-163	523.0	COG0624@1|root,COG0624@2|Bacteria,1TQS9@1239|Firmicutes,4HDHW@91061|Bacilli,26UDI@186822|Paenibacillaceae	91061|Bacilli	E	Peptidase family M20/M25/M40	-	-	3.5.1.16,3.5.1.18	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R00669,R02734,R09107	RC00064,RC00090,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
CMS1_k127_4808213_7	643473.KB235930_gene3809	0.0001283	47.0	2BGW7@1|root,32AW1@2|Bacteria,1G7FK@1117|Cyanobacteria,1HSIC@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4808758_5	179408.Osc7112_4373	9.735e-20	104.0	COG0438@1|root,COG0457@1|root,COG0859@1|root,COG0438@2|Bacteria,COG0457@2|Bacteria,COG0859@2|Bacteria,1G193@1117|Cyanobacteria,1H799@1150|Oscillatoriales	1117|Cyanobacteria	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF4915,Glyco_transf_9,Glycos_transf_1,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
CMS1_k127_4808758_1	926550.CLDAP_34270	3.488e-105	351.0	COG1482@1|root,COG1482@2|Bacteria,2G6I2@200795|Chloroflexi	200795|Chloroflexi	G	PFAM mannose-6-phosphate isomerase type I	-	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	PMI_typeI
CMS1_k127_4808758_3	926550.CLDAP_34250	3.324e-62	225.0	COG0696@1|root,COG0696@2|Bacteria,2G7GD@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	-	-	-	-	-	-	-	-	-	-	-	-	Metalloenzyme
CMS1_k127_4808758_4	485916.Dtox_2823	1.981e-28	121.0	COG4122@1|root,COG4122@2|Bacteria,1UF4M@1239|Firmicutes,24B70@186801|Clostridia,261M7@186807|Peptococcaceae	186801|Clostridia	S	PFAM O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_3
CMS1_k127_4808758_6	765420.OSCT_1119	1.025e-07	65.0	COG0642@1|root,COG2205@2|Bacteria,2G5YI@200795|Chloroflexi,37540@32061|Chloroflexia	32061|Chloroflexia	T	N-terminal 7TM region of histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_7TM
CMS1_k127_4808758_2	926550.CLDAP_27070	1.014e-67	242.0	2BWNB@1|root,32WFI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4808758_0	224325.AF_1815	2.713e-116	380.0	COG4992@1|root,arCOG00914@2157|Archaea,2XTKV@28890|Euryarchaeota,24610@183980|Archaeoglobi	28890|Euryarchaeota	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	lysJ	GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	-	ko:K05830	ko00220,ko00300,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01130,map01210,map01230	M00031,M00763	R09778,R10932	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CMS1_k127_4819012_4	768704.Desmer_0002	0.0001926	53.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,2490S@186801|Clostridia,260P2@186807|Peptococcaceae	186801|Clostridia	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
CMS1_k127_4819012_1	1210884.HG799464_gene11306	7.376e-32	140.0	COG5534@1|root,COG5534@2|Bacteria,2IZC7@203682|Planctomycetes	203682|Planctomycetes	L	Replication initiator protein A	-	-	-	-	-	-	-	-	-	-	-	-	RPA
CMS1_k127_4819012_2	644966.Tmar_2366	1.186e-31	136.0	COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,249VV@186801|Clostridia,3WCHW@538999|Clostridiales incertae sedis	186801|Clostridia	K	Belongs to the ParB family	spo0J	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
CMS1_k127_4819012_0	525904.Tter_0941	4.452e-80	274.0	COG1192@1|root,COG1192@2|Bacteria,2NQVW@2323|unclassified Bacteria	2|Bacteria	D	4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family	soj	GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
CMS1_k127_4829134_0	911045.PSE_1026	1.333e-28	120.0	29YAY@1|root,30K56@2|Bacteria,1P8DZ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4829134_3	1128421.JAGA01000002_gene1598	1.464e-07	64.0	COG1807@1|root,COG1807@2|Bacteria,2NRMD@2323|unclassified Bacteria	2|Bacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS1_k127_4829134_1	1121091.AUMP01000033_gene1564	1.878e-23	107.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,4HC17@91061|Bacilli	91061|Bacilli	K	Belongs to the sigma-70 factor family. ECF subfamily	sigW	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_4829134_2	661478.OP10G_2200	6.602e-17	89.0	2DQGC@1|root,336PP@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4872)	-	-	-	-	-	-	-	-	-	-	-	-	BtrH_N,DUF4872
CMS1_k127_4836774_4	926550.CLDAP_24180	8.577e-157	500.0	COG0667@1|root,COG0667@2|Bacteria,2G7T1@200795|Chloroflexi	200795|Chloroflexi	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS1_k127_4836774_5	179408.Osc7112_1695	1.586e-135	438.0	COG2207@1|root,COG2207@2|Bacteria,1G0B1@1117|Cyanobacteria,1HDY1@1150|Oscillatoriales	1117|Cyanobacteria	K	PFAM AraC-type transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AraC_N,HTH_18
CMS1_k127_4836774_9	511051.CSE_11920	5.922e-80	276.0	COG2116@1|root,COG2116@2|Bacteria	2|Bacteria	P	formate transmembrane transporter activity	focA	GO:0003674,GO:0005215,GO:0005342,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008028,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015318,GO:0015499,GO:0015711,GO:0015718,GO:0015724,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0042802,GO:0042891,GO:0042895,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098656,GO:1903825,GO:1905039	-	ko:K03459,ko:K06212,ko:K21993	-	-	-	-	ko00000,ko02000	1.A.16.1.1,1.A.16.1.2,1.A.16.1.3,1.A.16.2	-	iB21_1397.B21_02346,iECBD_1354.ECBD_1196,iECB_1328.ECB_02384,iECD_1391.ECD_02384,iECIAI39_1322.ECIAI39_2632,iEcSMS35_1347.EcSMS35_2639,iSF_1195.SF0899,iS_1188.S0963	CBS,Form_Nir_trans
CMS1_k127_4836774_11	479432.Sros_5737	2.053e-66	239.0	COG1063@1|root,COG1063@2|Bacteria,2GMNX@201174|Actinobacteria,4EQQJ@85012|Streptosporangiales	201174|Actinobacteria	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_4836774_15	1408254.T458_19885	1.73e-52	196.0	COG1402@1|root,COG1402@2|Bacteria,1V0N8@1239|Firmicutes,4HK2P@91061|Bacilli,276QJ@186822|Paenibacillaceae	91061|Bacilli	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
CMS1_k127_4836774_3	886293.Sinac_0917	1.38e-165	529.0	COG4948@1|root,COG4948@2|Bacteria,2IX5W@203682|Planctomycetes	203682|Planctomycetes	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
CMS1_k127_4836774_19	1536775.H70737_02075	1.097e-10	73.0	2F3MY@1|root,33WF3@2|Bacteria,1UIQE@1239|Firmicutes,4ISQA@91061|Bacilli,26T8T@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
CMS1_k127_4836774_17	1298864.AUEQ01000006_gene5211	1.101e-28	119.0	COG4910@1|root,COG4910@2|Bacteria,2IN09@201174|Actinobacteria,23A8V@1762|Mycobacteriaceae	201174|Actinobacteria	Q	Dehydratase small subunit	-	-	4.2.1.28	ko:K13920	ko00640,map00640	-	R02376	RC00707	ko00000,ko00001,ko01000	-	-	-	Dehydratase_SU
CMS1_k127_4836774_0	247490.KSU1_B0582	0.0	1245.0	COG3227@1|root,COG4935@1|root,COG3227@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	3.4.24.28	ko:K01400,ko:K01417,ko:K20274	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CARDB,CarboxypepD_reg,DUF11,F5_F8_type_C,FTP,P_proprotein,Peptidase_M36,Peptidase_S8
CMS1_k127_4836774_16	634956.Geoth_1928	1.328e-39	169.0	COG4909@1|root,COG4909@2|Bacteria,1UT3J@1239|Firmicutes,4HFWN@91061|Bacilli	91061|Bacilli	Q	Dehydratase	pduD	-	4.2.1.28	ko:K13919	ko00640,map00640	-	R02376	RC00707	ko00000,ko00001,ko01000	-	-	-	Dehydratase_MU
CMS1_k127_4836774_2	1121430.JMLG01000004_gene924	2.132e-229	732.0	COG4909@1|root,COG4909@2|Bacteria,1TPU7@1239|Firmicutes,24AFR@186801|Clostridia,26436@186807|Peptococcaceae	186801|Clostridia	Q	Dehydratase large subunit	dhaB	-	4.2.1.28,4.2.1.30	ko:K01699,ko:K06120	ko00561,ko00640,map00561,map00640	-	R01047,R02376	RC00429,RC00707	ko00000,ko00001,ko01000	-	-	-	Dehydratase_LU
CMS1_k127_4836774_13	118168.MC7420_1583	1.184e-58	232.0	COG1357@1|root,COG1357@2|Bacteria,1G5FM@1117|Cyanobacteria,1HA7H@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
CMS1_k127_4836774_8	1128421.JAGA01000001_gene2146	5.236e-86	317.0	2CA5R@1|root,2Z81H@2|Bacteria,2NRJU@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4153
CMS1_k127_4836774_10	402777.KB235898_gene5286	8.861e-67	237.0	COG2194@1|root,COG2194@2|Bacteria,1G0XR@1117|Cyanobacteria,1HAKG@1150|Oscillatoriales	1117|Cyanobacteria	S	sulfuric ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4836774_7	756067.MicvaDRAFT_1841	1.362e-109	367.0	COG1672@1|root,COG1672@2|Bacteria,1G15R@1117|Cyanobacteria,1HHE7@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Archaeal ATPase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4836774_1	1173028.ANKO01000112_gene4922	1.121e-238	768.0	COG1672@1|root,COG1672@2|Bacteria,1G4AU@1117|Cyanobacteria,1HAF9@1150|Oscillatoriales	1117|Cyanobacteria	S	Pfam:Arch_ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
CMS1_k127_4836774_14	251229.Chro_2803	2.249e-53	191.0	COG1846@1|root,COG1846@2|Bacteria,1G6XI@1117|Cyanobacteria	1117|Cyanobacteria	K	MarR family transcriptional	-	-	-	ko:K15973	-	-	-	-	ko00000,ko03000	-	-	-	MarR
CMS1_k127_4836774_6	1121382.JQKG01000004_gene4029	4.199e-117	385.0	COG0346@1|root,COG0346@2|Bacteria,1WICF@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K15975	-	-	-	-	ko00000	-	-	-	Abhydrolase_2,Glyoxalase
CMS1_k127_4836774_12	485913.Krac_5625	5.447e-60	211.0	COG0400@1|root,COG0400@2|Bacteria,2G8M6@200795|Chloroflexi	200795|Chloroflexi	S	Phospholipase/Carboxylesterase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
CMS1_k127_4840135_3	479434.Sthe_1008	6.223e-18	89.0	COG0454@1|root,COG0456@2|Bacteria,2G6N6@200795|Chloroflexi	200795|Chloroflexi	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS1_k127_4840135_5	416348.Hlac_2685	1.865e-05	53.0	COG0456@1|root,arCOG00833@2157|Archaea,2Y0G0@28890|Euryarchaeota,23WBW@183963|Halobacteria	183963|Halobacteria	K	COG0456 Acetyltransferases	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
CMS1_k127_4840135_2	1408437.JNJN01000017_gene2250	7.782e-27	119.0	COG1670@1|root,COG1670@2|Bacteria,1TQUK@1239|Firmicutes,24BF7@186801|Clostridia,25WKU@186806|Eubacteriaceae	186801|Clostridia	J	GNAT acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	GNAT_acetyltran
CMS1_k127_4840135_4	1444712.BN1013_01006	4.425e-06	49.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	yokL3	-	2.3.1.57	ko:K00657,ko:K07023	ko00330,ko01100,ko04216,map00330,map01100,map04216	M00135	R01154	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_3
CMS1_k127_4840135_0	485913.Krac_4709	1.201e-54	203.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	2.3.1.4	ko:K00621	ko00520,map00520	-	R02058	RC00004,RC00166	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1
CMS1_k127_4840135_1	1068980.ARVW01000001_gene5314	5.692e-27	119.0	COG3173@1|root,COG3173@2|Bacteria,2HH8W@201174|Actinobacteria,4E34T@85010|Pseudonocardiales	2|Bacteria	S	Phosphotransferase enzyme family	-	-	2.7.1.119	ko:K17880	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	APH
CMS1_k127_484146_4	1303518.CCALI_02457	2.368e-11	72.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	2.3.1.128	ko:K03789,ko:K06323	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
CMS1_k127_484146_0	543526.Htur_1030	4.857e-173	555.0	COG0277@1|root,arCOG00340@2157|Archaea,2Y85H@28890|Euryarchaeota,24157@183963|Halobacteria	183963|Halobacteria	C	COG0277 FAD FMN-containing dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
CMS1_k127_484146_1	1173026.Glo7428_1707	6.129e-164	524.0	COG2890@1|root,COG2890@2|Bacteria	2|Bacteria	J	protein-(glutamine-N5) methyltransferase activity	-	-	2.1.1.156,2.1.1.157,2.1.1.209,2.1.1.4	ko:K00543,ko:K16130,ko:K18896,ko:K18897,ko:K21515	ko00260,ko00380,ko01054,ko01100,map00260,map00380,map01054,map01100	M00037	R03130,R04905,R10060,R10061	RC00003,RC00392,RC03038,RC03040	ko00000,ko00001,ko00002,ko01000,ko01008,ko03009	-	-	-	AMP-binding,Aminotran_1_2,AviRa,Condensation,Dimerisation2,Hen1_L,MTS,Methyltransf_12,Methyltransf_2,Methyltransf_23,Methyltransf_25,Methyltransf_31,PP-binding
CMS1_k127_484146_3	555088.DealDRAFT_1223	5.029e-15	89.0	COG2909@1|root,COG2909@2|Bacteria,1VKHN@1239|Firmicutes	1239|Firmicutes	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
CMS1_k127_484146_2	926560.KE387023_gene3263	1.921e-52	206.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,1WM5I@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12
CMS1_k127_4845707_1	246194.CHY_1212	1.362e-103	343.0	COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,248II@186801|Clostridia,42EMC@68295|Thermoanaerobacterales	186801|Clostridia	H	PFAM aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CMS1_k127_4845707_0	1229780.BN381_250054	1.651e-163	542.0	COG0383@1|root,COG0383@2|Bacteria	2|Bacteria	G	mannose metabolic process	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
CMS1_k127_4845707_2	269800.Tfu_2257	1.801e-60	225.0	COG0438@1|root,COG0438@2|Bacteria,2GIZG@201174|Actinobacteria,4EIFG@85012|Streptosporangiales	201174|Actinobacteria	M	Glycosyl transferase 4-like	-	-	2.4.1.337	ko:K19002	ko00561,ko01100,map00561,map01100	-	R10850	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
CMS1_k127_4845707_3	42256.RradSPS_2905	3.827e-09	59.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	mprF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.3.2.3	ko:K07027,ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00726	-	-	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	2.A.1.3.37,4.D.2	-	iYO844.BG12900	DUF2156,LPG_synthase_TM
CMS1_k127_48561_4	357808.RoseRS_2515	8.757e-66	228.0	COG1028@1|root,COG1028@2|Bacteria,2G8DK@200795|Chloroflexi,3776U@32061|Chloroflexia	32061|Chloroflexia	IQ	short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS1_k127_48561_8	10224.XP_002738304.1	3.507e-28	126.0	COG0620@1|root,KOG2263@2759|Eukaryota,38GZS@33154|Opisthokonta,3BNKS@33208|Metazoa,3E47H@33213|Bilateria	33208|Metazoa	E	Cobalamin-independent synthase, Catalytic domain	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
CMS1_k127_48561_0	502025.Hoch_4258	1.24e-297	932.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1P6E1@1224|Proteobacteria,437TW@68525|delta/epsilon subdivisions,2X33B@28221|Deltaproteobacteria,2YU23@29|Myxococcales	28221|Deltaproteobacteria	EU	peptidase S9B dipeptidylpeptidase IV domain protein	-	-	3.4.14.5	ko:K01278	ko04974,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	DPPIV_N,Peptidase_S9
CMS1_k127_48561_2	485913.Krac_10989	5.069e-239	751.0	COG1061@1|root,COG1061@2|Bacteria,2G861@200795|Chloroflexi	200795|Chloroflexi	L	type III restriction protein res subunit	-	-	3.6.4.12	ko:K10843	ko03022,ko03420,map03022,map03420	M00290	-	-	ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	ERCC3_RAD25_C,Helicase_C_3,ResIII
CMS1_k127_48561_1	1499967.BAYZ01000157_gene589	1.47e-246	766.0	COG1486@1|root,COG1486@2|Bacteria,2NQ9I@2323|unclassified Bacteria	2|Bacteria	G	Family 4 glycosyl hydrolase	-	-	3.2.1.22,3.2.1.86	ko:K01222,ko:K07406	ko00010,ko00052,ko00500,ko00561,ko00600,ko00603,map00010,map00052,map00500,map00561,map00600,map00603	-	R00839,R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05133,R05134,R05549,R05961,R06091	RC00049,RC00059,RC00171,RC00451,RC00714	ko00000,ko00001,ko01000	-	GT4	-	Glyco_hydro_4,Glyco_hydro_4C
CMS1_k127_48561_3	357808.RoseRS_2891	5.806e-234	728.0	COG1486@1|root,COG1486@2|Bacteria,2G5M6@200795|Chloroflexi	200795|Chloroflexi	G	Family 4 glycosyl hydrolase	-	-	3.2.1.22	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_4,Glyco_hydro_4C
CMS1_k127_48561_5	1501230.ET33_36050	4.836e-55	197.0	COG0454@1|root,COG0456@2|Bacteria,1UTRR@1239|Firmicutes,4IS0V@91061|Bacilli,276ZV@186822|Paenibacillaceae	91061|Bacilli	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Clp_N
CMS1_k127_48561_7	743719.PaelaDRAFT_3980	5.682e-42	162.0	COG0454@1|root,COG0456@2|Bacteria,1V2CK@1239|Firmicutes,4HGP5@91061|Bacilli,26WI0@186822|Paenibacillaceae	91061|Bacilli	K	Acetyltransferase (GNAT) domain	yyaR	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS1_k127_48561_6	1278073.MYSTI_01384	3.939e-46	169.0	COG0317@1|root,COG0317@2|Bacteria,1N2BZ@1224|Proteobacteria,430HK@68525|delta/epsilon subdivisions,2WVNF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_4
CMS1_k127_4860452_1	351607.Acel_1510	3.249e-28	116.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
CMS1_k127_4860452_2	1123405.AUMM01000012_gene2272	2.794e-24	109.0	COG1595@1|root,COG1595@2|Bacteria,1V94Z@1239|Firmicutes,4HJG5@91061|Bacilli	91061|Bacilli	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_4860452_0	1382306.JNIM01000001_gene4186	5.459e-123	402.0	COG0714@1|root,COG0714@2|Bacteria,2G669@200795|Chloroflexi	200795|Chloroflexi	S	ATPase associated with various cellular activities, AAA_3	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS1_k127_4869836_0	316274.Haur_3458	2.666e-23	114.0	COG2203@1|root,COG2204@1|root,COG5002@1|root,COG2203@2|Bacteria,COG2204@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	phoR	GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0016036,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0035556,GO:0036211,GO:0042578,GO:0042594,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071496,GO:0071704,GO:0071944,GO:0140096,GO:1901564	2.7.13.3	ko:K02484,ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF3329,HATPase_c,HisKA,PAS,PAS_8
CMS1_k127_4869836_1	1177154.Y5S_03775	2.561e-12	75.0	2DNZB@1|root,32ZW6@2|Bacteria,1QMYT@1224|Proteobacteria,1TM16@1236|Gammaproteobacteria,1XQD8@135619|Oceanospirillales	135619|Oceanospirillales	S	Cysteine-rich CPCC	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_CPCC
CMS1_k127_4883084_6	1122919.KB905555_gene984	3.926e-23	101.0	COG2890@1|root,COG2890@2|Bacteria,1V4FF@1239|Firmicutes,4HHHN@91061|Bacilli,26XJ6@186822|Paenibacillaceae	91061|Bacilli	J	RRNA methyltransferase AviRa	-	-	2.1.1.209	ko:K21515	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	AviRa
CMS1_k127_4883084_9	1123400.KB904754_gene983	1.025e-14	85.0	COG1708@1|root,COG2105@1|root,COG1708@2|Bacteria,COG2105@2|Bacteria,1N814@1224|Proteobacteria,1SB38@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Gamma-glutamyl cyclotransferase, AIG2-like	-	-	-	-	-	-	-	-	-	-	-	-	GGACT
CMS1_k127_4883084_1	926550.CLDAP_32590	8.954e-151	489.0	COG1349@1|root,COG2865@1|root,COG1349@2|Bacteria,COG2865@2|Bacteria,2G7JP@200795|Chloroflexi	2|Bacteria	K	PFAM AAA-4 family protein	-	-	3.6.4.12	ko:K02444,ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	AlbA_2,DUF1670,DeoRC,HATPase_c_4,HTH_DeoR
CMS1_k127_4883084_4	1128421.JAGA01000001_gene2365	1.257e-118	391.0	COG1600@1|root,COG1600@2|Bacteria,2NNWV@2323|unclassified Bacteria	2|Bacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
CMS1_k127_4883084_7	1210884.HG799462_gene8487	5.08e-23	104.0	COG0517@1|root,COG0517@2|Bacteria,2J0FD@203682|Planctomycetes	203682|Planctomycetes	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
CMS1_k127_4883084_0	756272.Plabr_2853	1.458e-242	763.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2IXH6@203682|Planctomycetes	203682|Planctomycetes	C	Pyruvate ferredoxin oxidoreductase and related	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
CMS1_k127_4883084_2	530564.Psta_0806	1.044e-148	486.0	COG1013@1|root,COG1013@2|Bacteria,2IY6Z@203682|Planctomycetes	203682|Planctomycetes	C	COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
CMS1_k127_4883084_3	3067.XP_002948919.1	3.151e-130	422.0	COG0190@1|root,KOG0089@2759|Eukaryota,37K6Z@33090|Viridiplantae,34H22@3041|Chlorophyta	3041|Chlorophyta	H	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
CMS1_k127_4883084_8	926550.CLDAP_22180	8.553e-21	105.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
CMS1_k127_4883084_5	479434.Sthe_1850	3.71e-100	348.0	COG0419@1|root,COG0419@2|Bacteria,2G682@200795|Chloroflexi,27XPG@189775|Thermomicrobia	189775|Thermomicrobia	L	Rad50 zinc hook motif	-	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,Rad50_zn_hook,SbcCD_C
CMS1_k127_4884629_1	1210884.HG799468_gene13564	1.131e-17	83.0	COG0520@1|root,COG0520@2|Bacteria,2IZJW@203682|Planctomycetes	203682|Planctomycetes	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
CMS1_k127_4884629_0	1304880.JAGB01000002_gene1778	1.075e-120	401.0	COG0673@1|root,COG0673@2|Bacteria,1UY90@1239|Firmicutes,24DQA@186801|Clostridia	186801|Clostridia	S	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_4887982_4	765420.OSCT_2800	2.119e-12	78.0	COG3903@1|root,COG3903@2|Bacteria,2GBIP@200795|Chloroflexi,376KC@32061|Chloroflexia	32061|Chloroflexia	K	NB-ARC domain	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC,TPR_12
CMS1_k127_4887982_2	313612.L8106_14990	2.415e-21	105.0	COG2856@1|root,COG2856@2|Bacteria,1G0X5@1117|Cyanobacteria,1H9SD@1150|Oscillatoriales	1117|Cyanobacteria	E	IrrE N-terminal-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M78
CMS1_k127_4887982_3	1173028.ANKO01000036_gene3683	6.611e-14	76.0	COG1426@1|root,COG1426@2|Bacteria,1GQRC@1117|Cyanobacteria,1HI75@1150|Oscillatoriales	1117|Cyanobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19
CMS1_k127_4887982_0	1499967.BAYZ01000184_gene4600	3.996e-169	538.0	COG4608@1|root,COG4608@2|Bacteria,2NQH4@2323|unclassified Bacteria	2|Bacteria	P	Oligopeptide/dipeptide transporter, C-terminal region	gsiA_8	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
CMS1_k127_4887982_1	1499967.BAYZ01000184_gene4599	4.539e-46	168.0	COG0444@1|root,COG0444@2|Bacteria	2|Bacteria	P	Belongs to the ABC transporter superfamily	oppD	-	-	ko:K02031,ko:K02032,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
CMS1_k127_4892181_0	357808.RoseRS_1075	9.799e-148	485.0	COG0577@1|root,COG0577@2|Bacteria,2G68F@200795|Chloroflexi,376ZY@32061|Chloroflexia	32061|Chloroflexia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS1_k127_4892181_1	35754.JNYJ01000009_gene1953	5.81e-59	230.0	COG0457@1|root,COG3629@1|root,COG3903@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG3903@2|Bacteria,2H3FC@201174|Actinobacteria	201174|Actinobacteria	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD
CMS1_k127_4897461_3	1246459.KB898355_gene4106	5.897e-45	167.0	COG1082@1|root,COG1082@2|Bacteria,1N1AK@1224|Proteobacteria,2U3TU@28211|Alphaproteobacteria,4BB6Q@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS1_k127_4897461_2	32057.KB217478_gene1744	1.402e-84	296.0	COG1028@1|root,COG1028@2|Bacteria,1GJY4@1117|Cyanobacteria,1HSV8@1161|Nostocales	1117|Cyanobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS1_k127_4897461_0	326427.Cagg_1752	6.999e-115	377.0	COG0601@1|root,COG0601@2|Bacteria	2|Bacteria	P	nitrogen compound transport	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_4897461_1	177437.HRM2_44150	1.845e-97	326.0	COG0444@1|root,COG4608@1|root,COG0444@2|Bacteria,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,42TDH@68525|delta/epsilon subdivisions,2X758@28221|Deltaproteobacteria,2MPK7@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
CMS1_k127_4898944_3	1121396.KB893122_gene3043	6.751e-34	135.0	COG5499@1|root,COG5499@2|Bacteria,1N89F@1224|Proteobacteria,42XNP@68525|delta/epsilon subdivisions,2WSJU@28221|Deltaproteobacteria,2MNH3@213118|Desulfobacterales	28221|Deltaproteobacteria	K	regulator	-	-	-	ko:K18831	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	HTH_3
CMS1_k127_4898944_2	1384049.CD29_05950	1.181e-53	197.0	COG2071@1|root,COG2071@2|Bacteria,1V1KC@1239|Firmicutes,4HI59@91061|Bacilli,3IXCI@400634|Lysinibacillus	91061|Bacilli	S	Peptidase C26	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
CMS1_k127_4898944_1	926550.CLDAP_23360	1.192e-58	211.0	COG0745@1|root,COG1716@1|root,COG0745@2|Bacteria,COG1716@2|Bacteria,2G8QX@200795|Chloroflexi	200795|Chloroflexi	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
CMS1_k127_4898944_0	926550.CLDAP_23370	1.972e-104	345.0	COG0515@1|root,COG0515@2|Bacteria,2G850@200795|Chloroflexi	200795|Chloroflexi	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS1_k127_4904741_0	743525.TSC_c11660	1.492e-92	330.0	COG3629@1|root,COG3899@1|root,COG3629@2|Bacteria,COG3899@2|Bacteria,1WKSF@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD
CMS1_k127_4904741_2	404589.Anae109_3347	6.948e-33	137.0	COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,1NKQ0@1224|Proteobacteria	1224|Proteobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD
CMS1_k127_4904741_1	1122179.KB890421_gene2573	3.703e-73	250.0	COG0644@1|root,COG0644@2|Bacteria,4P00N@976|Bacteroidetes	976|Bacteroidetes	C	Tryptophan halogenase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3,Trp_halogenase
CMS1_k127_4908117_2	552811.Dehly_1715	2.346e-38	151.0	COG1040@1|root,COG1040@2|Bacteria,2G6WB@200795|Chloroflexi,34CXG@301297|Dehalococcoidia	301297|Dehalococcoidia	S	competence protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4908117_3	926550.CLDAP_36380	5.148e-38	149.0	COG1544@1|root,COG1544@2|Bacteria,2G6Z4@200795|Chloroflexi	200795|Chloroflexi	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
CMS1_k127_4908117_1	321327.CYA_1063	3.119e-56	200.0	COG0105@1|root,COG0105@2|Bacteria,1G4ZN@1117|Cyanobacteria,1GYKN@1129|Synechococcus	1117|Cyanobacteria	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006165,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:1901360	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
CMS1_k127_4908117_0	926550.CLDAP_22920	5.608e-193	612.0	COG0178@1|root,COG0178@2|Bacteria,2G60U@200795|Chloroflexi	200795|Chloroflexi	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
CMS1_k127_4912278_5	1215092.PA6_008_00210	1.367e-29	139.0	COG2114@1|root,COG3629@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3629@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,1S0DF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,Guanylate_cyc
CMS1_k127_4912278_0	1173023.KE650771_gene5533	9.101e-225	746.0	COG2319@1|root,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1JJVB@1189|Stigonemataceae	1117|Cyanobacteria	K	NB-ARC domain	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC,Pentapeptide,WD40
CMS1_k127_4912278_6	255470.cbdbA1387	1.774e-05	47.0	COG0501@1|root,COG0501@2|Bacteria,2G6KE@200795|Chloroflexi,34D32@301297|Dehalococcoidia	301297|Dehalococcoidia	O	CAAX prenyl protease N-terminal, five membrane helices	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
CMS1_k127_4912278_3	1382306.JNIM01000001_gene3678	3.512e-37	146.0	COG0501@1|root,COG0501@2|Bacteria,2G6KE@200795|Chloroflexi	200795|Chloroflexi	O	PFAM peptidase M48 Ste24p	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
CMS1_k127_4912278_2	234267.Acid_5062	5.045e-52	187.0	COG1312@1|root,COG1312@2|Bacteria,3Y6UB@57723|Acidobacteria	57723|Acidobacteria	G	D-mannonate dehydratase (UxuA)	-	-	4.2.1.8	ko:K01686	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	UxuA
CMS1_k127_4912278_4	1210884.HG799471_gene14682	1.155e-32	136.0	COG0500@1|root,COG2226@2|Bacteria,2J1IZ@203682|Planctomycetes	203682|Planctomycetes	Q	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS1_k127_4912278_1	1147.D082_34190	1.507e-65	245.0	COG0747@1|root,COG0747@2|Bacteria,1G0S3@1117|Cyanobacteria,1H6HB@1142|Synechocystis	1117|Cyanobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_4939713_4	3075.A0A087SRP8	4.221e-18	86.0	COG0165@1|root,KOG1316@2759|Eukaryota,37J59@33090|Viridiplantae,34JIC@3041|Chlorophyta	3041|Chlorophyta	E	Argininosuccinate lyase	-	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
CMS1_k127_4939713_3	926569.ANT_28280	3.248e-26	109.0	COG0361@1|root,COG0361@2|Bacteria,2G7AQ@200795|Chloroflexi	200795|Chloroflexi	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
CMS1_k127_4939713_0	748449.Halha_0399	1.237e-129	429.0	COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,2489V@186801|Clostridia,3WABC@53433|Halanaerobiales	186801|Clostridia	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PEP-utilizers,PK,PK_C
CMS1_k127_4939713_2	118168.MC7420_5252	6.427e-33	133.0	COG2944@1|root,COG2944@2|Bacteria,1G6V7@1117|Cyanobacteria,1HBR9@1150|Oscillatoriales	1117|Cyanobacteria	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
CMS1_k127_4939713_1	255470.cbdbA524	1.861e-38	145.0	COG0419@1|root,COG0419@2|Bacteria,2G682@200795|Chloroflexi,34CWU@301297|Dehalococcoidia	301297|Dehalococcoidia	L	Putative exonuclease SbcCD, C subunit	-	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SbcCD_C
CMS1_k127_4940614_5	1123277.KB893228_gene2052	2.72e-24	106.0	COG1574@1|root,COG1574@2|Bacteria,4NFMV@976|Bacteroidetes,47TV8@768503|Cytophagia	976|Bacteroidetes	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
CMS1_k127_4940614_6	869210.Marky_1921	5.009e-10	69.0	COG0517@1|root,COG5485@1|root,COG0517@2|Bacteria,COG5485@2|Bacteria,1WK3F@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
CMS1_k127_4940614_0	485913.Krac_2926	1.114e-163	546.0	COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2G7W3@200795|Chloroflexi	200795|Chloroflexi	K	transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,GerE,NB-ARC,TPR_12
CMS1_k127_4940614_3	1408254.T458_00735	5.41e-61	219.0	COG0778@1|root,COG0778@2|Bacteria,1UB8S@1239|Firmicutes,4HEGP@91061|Bacilli,26TNF@186822|Paenibacillaceae	91061|Bacilli	C	NAD(P)H-dependent oxidoreductase	nfrA	-	1.5.1.38	ko:K10678,ko:K19285	ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120	-	R05706,R08014,R08017,R08042	RC00126,RC00250	ko00000,ko00001,ko01000	-	-	-	Nitroreductase
CMS1_k127_4940614_1	234267.Acid_2605	4.783e-94	314.0	COG2133@1|root,COG2133@2|Bacteria,3Y3FI@57723|Acidobacteria	57723|Acidobacteria	G	Domain of Unknown Function (DUF1080)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1080
CMS1_k127_4940614_4	1469245.JFBG01000008_gene751	3.624e-60	214.0	COG0778@1|root,COG0778@2|Bacteria,1NCBD@1224|Proteobacteria,1SVTW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CMS1_k127_4940614_2	234267.Acid_1144	2.279e-88	298.0	COG3391@1|root,COG3391@2|Bacteria,3Y98W@57723|Acidobacteria	57723|Acidobacteria	S	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NHL
CMS1_k127_4941091_5	1120950.KB892802_gene1415	9.583e-124	405.0	COG4608@1|root,COG4608@2|Bacteria,2IBD7@201174|Actinobacteria,4DU7N@85009|Propionibacteriales	2|Bacteria	E	Oligopeptide/dipeptide transporter, C-terminal region	nikV	-	3.6.3.24	ko:K02031,ko:K02032,ko:K10823,ko:K10824	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439,M00440	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
CMS1_k127_4941091_7	1382356.JQMP01000001_gene960	8.141e-120	393.0	COG0444@1|root,COG0444@2|Bacteria,2GBE3@200795|Chloroflexi,27Z2B@189775|Thermomicrobia	189775|Thermomicrobia	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
CMS1_k127_4941091_13	1120950.KB892802_gene1417	5.258e-86	293.0	COG1173@1|root,COG1173@2|Bacteria,2GMJC@201174|Actinobacteria,4DTND@85009|Propionibacteriales	201174|Actinobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_4941091_6	309801.trd_1951	1.465e-120	395.0	COG0601@1|root,COG0601@2|Bacteria,2GAQS@200795|Chloroflexi,27YWJ@189775|Thermomicrobia	189775|Thermomicrobia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_4941091_0	1382356.JQMP01000001_gene961	2.039e-175	569.0	COG0747@1|root,COG0747@2|Bacteria,2GASZ@200795|Chloroflexi,27YY9@189775|Thermomicrobia	189775|Thermomicrobia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_4941091_4	357808.RoseRS_0178	4.159e-131	454.0	COG0577@1|root,COG0577@2|Bacteria,2G5WX@200795|Chloroflexi	200795|Chloroflexi	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
CMS1_k127_4941091_15	471853.Bcav_0935	4.837e-63	229.0	COG5285@1|root,COG5285@2|Bacteria,2IPFS@201174|Actinobacteria	201174|Actinobacteria	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
CMS1_k127_4941091_1	383372.Rcas_2455	2.677e-145	468.0	COG4608@1|root,COG4608@2|Bacteria,2G5R5@200795|Chloroflexi,3754I@32061|Chloroflexia	200795|Chloroflexi	P	TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
CMS1_k127_4941091_3	383372.Rcas_2451	3.459e-133	435.0	COG0444@1|root,COG0444@2|Bacteria,2G893@200795|Chloroflexi	200795|Chloroflexi	P	TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
CMS1_k127_4941091_2	1219084.AP014508_gene1007	5.037e-134	441.0	COG1173@1|root,COG1173@2|Bacteria,2GCBY@200918|Thermotogae	200918|Thermotogae	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
CMS1_k127_4941091_8	1122214.AQWH01000028_gene155	9.992e-115	378.0	COG0601@1|root,COG0601@2|Bacteria,1MWXF@1224|Proteobacteria,2TR7C@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_4941091_10	390874.Tpet_1677	2.59e-102	359.0	COG0747@1|root,COG0747@2|Bacteria,2GCNZ@200918|Thermotogae	200918|Thermotogae	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_4941091_12	926569.ANT_13700	7.116e-98	330.0	COG1609@1|root,COG1609@2|Bacteria,2G6BD@200795|Chloroflexi	200795|Chloroflexi	K	Periplasmic binding protein-like domain	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
CMS1_k127_4941091_11	926550.CLDAP_19970	6.767e-98	328.0	COG0395@1|root,COG0395@2|Bacteria,2G7M8@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_4941091_9	926550.CLDAP_19980	8.886e-111	365.0	COG1175@1|root,COG1175@2|Bacteria,2G6TJ@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_4941091_14	926550.CLDAP_19990	2.829e-68	250.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
CMS1_k127_4948923_5	926569.ANT_05570	1.421e-18	87.0	COG1816@1|root,COG1816@2|Bacteria,2G6AT@200795|Chloroflexi	200795|Chloroflexi	F	PFAM Adenosine AMP deaminase	-	-	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
CMS1_k127_4948923_2	926550.CLDAP_19020	2.05e-65	235.0	COG0491@1|root,COG0491@2|Bacteria,2G9AW@200795|Chloroflexi	200795|Chloroflexi	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS1_k127_4948923_0	326427.Cagg_3343	8.931e-151	485.0	COG0863@1|root,COG2189@1|root,COG0863@2|Bacteria,COG2189@2|Bacteria,2GAC9@200795|Chloroflexi,376M5@32061|Chloroflexia	32061|Chloroflexia	H	PFAM DNA methylase N-4 N-6 domain protein	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
CMS1_k127_4948923_3	696281.Desru_1825	6.112e-39	149.0	COG3603@1|root,COG3603@2|Bacteria,1V9Y8@1239|Firmicutes,24JKN@186801|Clostridia,2663Q@186807|Peptococcaceae	186801|Clostridia	S	ACT domain	-	-	-	ko:K09707	-	-	-	-	ko00000	-	-	-	ACT_7
CMS1_k127_4948923_1	926550.CLDAP_01110	6.804e-117	394.0	COG0728@1|root,COG0728@2|Bacteria,2G5MD@200795|Chloroflexi	200795|Chloroflexi	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	-	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
CMS1_k127_4948923_6	63737.Npun_R2559	1.022e-15	84.0	COG1357@1|root,COG1357@2|Bacteria,1G78U@1117|Cyanobacteria,1HMKT@1161|Nostocales	1117|Cyanobacteria	T	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
CMS1_k127_4948923_4	1499967.BAYZ01000010_gene5191	4.061e-22	97.0	COG2402@1|root,COG2402@2|Bacteria	2|Bacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07065	-	-	-	-	ko00000	-	-	-	PIN
CMS1_k127_4949051_0	926550.CLDAP_31090	1.363e-157	514.0	COG0747@1|root,COG0747@2|Bacteria,2G7MY@200795|Chloroflexi	200795|Chloroflexi	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_4949051_1	1121451.DESAM_22149	2.651e-60	228.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42Q40@68525|delta/epsilon subdivisions,2WKYI@28221|Deltaproteobacteria,2MA7Y@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	response regulator, receiver	-	-	-	ko:K02479	-	-	-	-	ko00000,ko02022	-	-	-	GerE,Response_reg
CMS1_k127_4949051_2	1238450.VIBNISOn1_80019	7.26e-33	134.0	COG2606@1|root,COG2606@2|Bacteria,1QJRS@1224|Proteobacteria,1SHYA@1236|Gammaproteobacteria,1XXFV@135623|Vibrionales	135623|Vibrionales	S	Aminoacyl-tRNA editing domain	-	-	-	ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
CMS1_k127_4949051_3	1313172.YM304_11330	1.826e-22	103.0	2E65M@1|root,330UB@2|Bacteria	2|Bacteria	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
CMS1_k127_4949051_4	439235.Dalk_0004	0.0001915	51.0	COG1572@1|root,COG1572@2|Bacteria,1NHGZ@1224|Proteobacteria,42XGC@68525|delta/epsilon subdivisions,2WSK0@28221|Deltaproteobacteria,2MM7M@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Propeptide_C25	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25,Propeptide_C25
CMS1_k127_4953190_2	1382356.JQMP01000003_gene2180	1.845e-19	90.0	COG1974@1|root,COG1974@2|Bacteria,2G6NC@200795|Chloroflexi,27Y6E@189775|Thermomicrobia	189775|Thermomicrobia	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
CMS1_k127_4953190_1	398767.Glov_3125	1.151e-128	426.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,42P7Z@68525|delta/epsilon subdivisions,2WK06@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
CMS1_k127_4953190_0	926550.CLDAP_08660	4.669e-168	541.0	COG1008@1|root,COG1008@2|Bacteria,2G5VU@200795|Chloroflexi	200795|Chloroflexi	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
CMS1_k127_4956439_2	1121380.JNIW01000067_gene1785	5.161e-74	258.0	COG4587@1|root,COG4587@2|Bacteria	2|Bacteria	S	transport system, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
CMS1_k127_4956439_1	926554.KI912620_gene1119	4.601e-89	301.0	COG3694@1|root,COG3694@2|Bacteria	2|Bacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
CMS1_k127_4956439_0	926554.KI912620_gene1118	9.01e-131	426.0	COG4586@1|root,COG4586@2|Bacteria	2|Bacteria	S	(ABC) transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_4957805_19	1233950.IW22_16660	2.172e-05	53.0	COG2253@1|root,COG2253@2|Bacteria,4NQ2B@976|Bacteroidetes,1II6N@117743|Flavobacteriia,3ZUH7@59732|Chryseobacterium	976|Bacteroidetes	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
CMS1_k127_4957805_3	1122605.KB893637_gene3182	2.335e-89	309.0	COG3356@1|root,COG3356@2|Bacteria,4P09D@976|Bacteroidetes	976|Bacteroidetes	S	PFAM Neutral alkaline nonlysosomal ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4957805_18	530564.Psta_3252	4.483e-07	61.0	COG0454@1|root,COG0456@2|Bacteria,2IZJ9@203682|Planctomycetes	203682|Planctomycetes	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS1_k127_4957805_1	1122917.KB899660_gene1492	7.219e-97	333.0	COG4948@1|root,COG4948@2|Bacteria,1TS0S@1239|Firmicutes,4HC1G@91061|Bacilli,26VB1@186822|Paenibacillaceae	91061|Bacilli	M	mandelate racemase muconate lactonizing	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
CMS1_k127_4957805_7	1303518.CCALI_00692	1.683e-62	226.0	COG2971@1|root,COG2971@2|Bacteria	2|Bacteria	G	N-acetylglucosamine kinase activity	nagk	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006040,GO:0006044,GO:0006082,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0045127,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901071,GO:1901135,GO:1901265,GO:1901363	2.7.1.59	ko:K00884	ko00520,ko01100,map00520,map01100	-	R01201	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	BcrAD_BadFG
CMS1_k127_4957805_17	266117.Rxyl_1184	7.826e-18	89.0	COG3871@1|root,COG3871@2|Bacteria,2I2TZ@201174|Actinobacteria	201174|Actinobacteria	S	pyridoxamine 5-phosphate	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
CMS1_k127_4957805_6	330084.JNYZ01000028_gene8375	8.633e-66	254.0	COG0383@1|root,COG0383@2|Bacteria,2I5ZD@201174|Actinobacteria	201174|Actinobacteria	G	Polysaccharide lyase family 4, domain III	-	-	-	-	-	-	-	-	-	-	-	-	CBM-like
CMS1_k127_4957805_9	1329516.JPST01000008_gene2017	3.385e-61	223.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,4HBAU@91061|Bacilli,27BN4@186824|Thermoactinomycetaceae	91061|Bacilli	GK	ROK family	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
CMS1_k127_4957805_14	1122927.KB895420_gene4173	2.872e-32	143.0	COG1653@1|root,COG1653@2|Bacteria,1TSBD@1239|Firmicutes,4HBMA@91061|Bacilli,277FS@186822|Paenibacillaceae	91061|Bacilli	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_8
CMS1_k127_4957805_4	697284.ERIC2_c33940	3.313e-84	289.0	COG0395@1|root,COG0395@2|Bacteria,1UY7D@1239|Firmicutes,4HCWU@91061|Bacilli,26QC7@186822|Paenibacillaceae	91061|Bacilli	G	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02026,ko:K10242	ko02010,map02010	M00206,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.23	-	-	BPD_transp_1
CMS1_k127_4957805_2	1111479.AXAR01000001_gene314	5.69e-96	324.0	COG1175@1|root,COG1175@2|Bacteria,1TPTZ@1239|Firmicutes,4HAIH@91061|Bacilli	91061|Bacilli	G	ABC-type sugar transport systems, permease components	ugpA7	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_4957805_15	880070.Cycma_0166	2.086e-25	120.0	COG3356@1|root,COG3356@2|Bacteria,4NUXP@976|Bacteroidetes	976|Bacteroidetes	S	PFAM Neutral alkaline nonlysosomal ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
CMS1_k127_4957805_13	530564.Psta_2338	1.529e-37	157.0	COG3356@1|root,COG3356@2|Bacteria,2IXKA@203682|Planctomycetes	203682|Planctomycetes	S	Neutral/alkaline non-lysosomal ceramidase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
CMS1_k127_4957805_20	1408424.JHYI01000025_gene1760	0.0008114	50.0	COG4288@1|root,COG4288@2|Bacteria,1V87Q@1239|Firmicutes,4HJH6@91061|Bacilli,1ZHA8@1386|Bacillus	91061|Bacilli	S	Anabaena sensory rhodopsin transducer	M1-951	-	-	-	-	-	-	-	-	-	-	-	ASRT
CMS1_k127_4957805_11	555088.DealDRAFT_1542	2.09e-46	177.0	COG2140@1|root,COG2140@2|Bacteria,1V13Z@1239|Firmicutes,25CH3@186801|Clostridia	186801|Clostridia	G	Glucose-6-phosphate isomerase (GPI)	-	-	-	-	-	-	-	-	-	-	-	-	GPI
CMS1_k127_4957805_5	926561.KB900618_gene55	2.676e-74	266.0	COG1486@1|root,COG1486@2|Bacteria,1TQ9I@1239|Firmicutes,24995@186801|Clostridia	186801|Clostridia	G	family 4	-	-	3.2.1.86	ko:K01222	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT4	-	Glyco_hydro_4,Glyco_hydro_4C
CMS1_k127_4957805_0	234267.Acid_0283	3.6e-131	428.0	COG0399@1|root,COG0399@2|Bacteria,3Y3PT@57723|Acidobacteria	57723|Acidobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
CMS1_k127_4957805_10	1382358.JHVN01000010_gene1529	5.335e-58	209.0	COG4821@1|root,COG4821@2|Bacteria,1TQS7@1239|Firmicutes,4HCR4@91061|Bacilli,21X32@150247|Anoxybacillus	91061|Bacilli	S	SIS domain	-	-	-	-	-	-	-	-	-	-	-	-	SIS_2
CMS1_k127_4957805_12	1382306.JNIM01000001_gene1421	2.378e-39	156.0	COG2188@1|root,COG2188@2|Bacteria,2G6ST@200795|Chloroflexi	200795|Chloroflexi	K	SPTR D1CI93 Phophonate C-P lyase system transcriptional regulator PhnF, GntR family	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
CMS1_k127_4957805_8	1122915.AUGY01000010_gene4529	5.765e-62	223.0	COG0451@1|root,COG0451@2|Bacteria,1TWPP@1239|Firmicutes,4HCTV@91061|Bacilli,26RTK@186822|Paenibacillaceae	91061|Bacilli	GM	epimerase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
CMS1_k127_4957805_16	1197130.BAFM01000022_gene2915	2.261e-19	96.0	COG4803@1|root,arCOG05227@2157|Archaea,2XXG6@28890|Euryarchaeota,23VR0@183963|Halobacteria	183963|Halobacteria	S	Protein of unknown function (DUF1269)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1269
CMS1_k127_4963302_0	401526.TcarDRAFT_0648	1.54e-137	452.0	COG3875@1|root,COG3875@2|Bacteria,1TQ1C@1239|Firmicutes,4H28D@909932|Negativicutes	909932|Negativicutes	S	Domain of unknown function (DUF2088)	-	-	5.1.2.1	ko:K22373	ko00620,map00620	-	R01450	RC00519	ko00000,ko00001,ko01000	-	-	-	DUF2088
CMS1_k127_4963302_1	1303518.CCALI_01379	1.29e-30	140.0	COG1413@1|root,COG2211@1|root,COG1413@2|Bacteria,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	3.4.11.2	ko:K01256,ko:K16210	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002,ko02000	2.A.2.5	-	-	HEAT_2,MFS_1
CMS1_k127_4968270_0	926550.CLDAP_02690	3.831e-181	575.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,2G5ZX@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
CMS1_k127_4968270_8	111780.Sta7437_0790	1.979e-55	198.0	COG3007@1|root,COG3007@2|Bacteria,1G5U3@1117|Cyanobacteria	1117|Cyanobacteria	I	enoyl-[acyl-carrier-protein] reductase (NADH) activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4968270_11	56110.Oscil6304_1756	6.067e-22	99.0	COG1669@1|root,COG1669@2|Bacteria,1G8RK@1117|Cyanobacteria,1HG84@1150|Oscillatoriales	1117|Cyanobacteria	S	nucleotidyltransferase activity	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	-
CMS1_k127_4968270_1	631362.Thi970DRAFT_04818	5.18e-152	500.0	COG0443@1|root,COG0443@2|Bacteria,1Q5TZ@1224|Proteobacteria,1RZCY@1236|Gammaproteobacteria,1WWTR@135613|Chromatiales	135613|Chromatiales	O	heat shock protein 70	-	-	-	-	-	-	-	-	-	-	-	iECO26_1355.ECO26_0725	HSP70
CMS1_k127_4968270_12	1499967.BAYZ01000012_gene2467	4.486e-21	102.0	COG0576@1|root,COG0576@2|Bacteria	2|Bacteria	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	-	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
CMS1_k127_4968270_14	1499967.BAYZ01000012_gene2466	3.59e-15	81.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
CMS1_k127_4968270_9	1499967.BAYZ01000012_gene2465	6.471e-46	190.0	COG3063@1|root,COG3063@2|Bacteria	2|Bacteria	NU	photosynthesis	-	-	-	ko:K02656	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	TPR_16,TPR_2,TPR_8
CMS1_k127_4968270_15	555088.DealDRAFT_1301	3.697e-06	53.0	COG5611@1|root,COG5611@2|Bacteria,1V69I@1239|Firmicutes,24HMU@186801|Clostridia	186801|Clostridia	S	PFAM PilT protein domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PIN
CMS1_k127_4968270_10	368407.Memar_1256	1.311e-26	112.0	COG0724@1|root,arCOG06896@2157|Archaea	2157|Archaea	S	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
CMS1_k127_4968270_7	272134.KB731324_gene2968	1.254e-56	200.0	COG1047@1|root,COG1047@2|Bacteria,1G5R4@1117|Cyanobacteria,1HBDB@1150|Oscillatoriales	1117|Cyanobacteria	O	PFAM FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C
CMS1_k127_4968270_4	251229.Chro_1416	5.744e-96	320.0	COG3340@1|root,COG3340@2|Bacteria,1G6TI@1117|Cyanobacteria,3VMJQ@52604|Pleurocapsales	1117|Cyanobacteria	E	Peptidase family S51	-	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S51
CMS1_k127_4968270_13	1120931.KB893949_gene1962	1.7e-17	92.0	COG2820@1|root,COG2820@2|Bacteria,1P0EC@1224|Proteobacteria,1RN3N@1236|Gammaproteobacteria,1Y6YB@135625|Pasteurellales	135625|Pasteurellales	F	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis	udp	-	2.4.2.3	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01876,R02484,R08229	RC00063	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
CMS1_k127_4968270_2	673860.AciM339_0160	8.258e-105	349.0	COG4608@1|root,arCOG00184@2157|Archaea,2Y5BH@28890|Euryarchaeota,3F31T@33867|unclassified Euryarchaeota	28890|Euryarchaeota	E	TIGRFAM oligopeptide dipeptide ABC transporter	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	iAF692.Mbar_A0472	ABC_tran,oligo_HPY
CMS1_k127_4968270_3	591019.Shell_1120	3.885e-99	335.0	COG0444@1|root,arCOG00181@2157|Archaea,2XPR3@28889|Crenarchaeota	28889|Crenarchaeota	E	TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
CMS1_k127_4968270_5	1499967.BAYZ01000132_gene306	2.957e-71	251.0	COG1173@1|root,COG1173@2|Bacteria	2|Bacteria	P	ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
CMS1_k127_4968270_6	1304874.JAFY01000002_gene135	1.084e-58	211.0	COG0601@1|root,COG0601@2|Bacteria,3TAG1@508458|Synergistetes	508458|Synergistetes	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_4970076_9	316274.Haur_1217	1.469e-92	334.0	COG0642@1|root,COG2202@1|root,COG3290@1|root,COG3829@1|root,COG3850@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3290@2|Bacteria,COG3829@2|Bacteria,COG3850@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.7.13.3,4.6.1.1	ko:K01768,ko:K11527,ko:K18143	ko00230,ko01501,ko02025,ko04113,ko04213,map00230,map01501,map02025,map04113,map04213	M00649,M00655,M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	CHASE,GAF,GGDEF,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
CMS1_k127_4970076_10	1444309.JAQG01000139_gene1538	6.081e-78	282.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,4HAM7@91061|Bacilli,26TIQ@186822|Paenibacillaceae	91061|Bacilli	E	ABC transporter substrate-binding protein	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_4970076_17	316274.Haur_1217	3.248e-29	134.0	COG0642@1|root,COG2202@1|root,COG3290@1|root,COG3829@1|root,COG3850@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3290@2|Bacteria,COG3829@2|Bacteria,COG3850@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.7.13.3,4.6.1.1	ko:K01768,ko:K11527,ko:K18143	ko00230,ko01501,ko02025,ko04113,ko04213,map00230,map01501,map02025,map04113,map04213	M00649,M00655,M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	CHASE,GAF,GGDEF,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
CMS1_k127_4970076_25	1144275.COCOR_00615	7.853e-08	60.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42MW4@68525|delta/epsilon subdivisions,2WKWD@28221|Deltaproteobacteria,2YXU5@29|Myxococcales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,PAS_4,Response_reg
CMS1_k127_4970076_3	1278073.MYSTI_00710	5.957e-173	549.0	COG3287@1|root,COG3287@2|Bacteria,1MVUZ@1224|Proteobacteria,42TFQ@68525|delta/epsilon subdivisions,2WPIZ@28221|Deltaproteobacteria,2YYD9@29|Myxococcales	28221|Deltaproteobacteria	S	FIST N domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
CMS1_k127_4970076_23	1121468.AUBR01000046_gene1908	1.54e-20	102.0	COG1082@1|root,COG1082@2|Bacteria,1V1Y1@1239|Firmicutes,24Y9G@186801|Clostridia,42HWD@68295|Thermoanaerobacterales	186801|Clostridia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS1_k127_4970076_1	926569.ANT_16680	3.757e-231	737.0	COG0317@1|root,COG0317@2|Bacteria,2G67Y@200795|Chloroflexi	200795|Chloroflexi	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
CMS1_k127_4970076_19	203119.Cthe_1268	8.797e-27	117.0	COG4585@1|root,COG4585@2|Bacteria,1TQI3@1239|Firmicutes,249R9@186801|Clostridia,3WN3W@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	degS	-	2.7.13.3	ko:K07777	ko02020,map02020	M00478	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DegS,HATPase_c,HisKA_3
CMS1_k127_4970076_5	926550.CLDAP_00360	2.113e-123	400.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
CMS1_k127_4970076_26	1276229.SSYRP_v1c04030	6.289e-05	53.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
CMS1_k127_4970076_14	326427.Cagg_3700	3.054e-60	219.0	COG1597@1|root,COG1597@2|Bacteria,2G6UK@200795|Chloroflexi,375KA@32061|Chloroflexia	32061|Chloroflexia	I	PFAM diacylglycerol kinase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
CMS1_k127_4970076_22	1118054.CAGW01000071_gene1857	2.434e-24	109.0	COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,4HC55@91061|Bacilli,26SNK@186822|Paenibacillaceae	91061|Bacilli	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
CMS1_k127_4970076_20	1340493.JNIF01000004_gene973	2.036e-26	113.0	COG0745@1|root,COG0745@2|Bacteria	1340493.JNIF01000004_gene973|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4970076_8	45157.CMK245CT	5.91e-100	336.0	COG0040@1|root,KOG2831@2759|Eukaryota	2759|Eukaryota	E	ATP phosphoribosyltransferase activity	-	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
CMS1_k127_4970076_4	1128421.JAGA01000001_gene2397	1.389e-157	509.0	COG0141@1|root,COG0141@2|Bacteria,2NNTS@2323|unclassified Bacteria	2|Bacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23,1.1.1.308	ko:K00013,ko:K15509	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1599	Histidinol_dh
CMS1_k127_4970076_6	926550.CLDAP_22110	1.922e-121	403.0	COG0079@1|root,COG0079@2|Bacteria,2G5U4@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS1_k127_4970076_12	326427.Cagg_2584	1.066e-70	244.0	COG0131@1|root,COG0131@2|Bacteria,2G6JA@200795|Chloroflexi,375HN@32061|Chloroflexia	32061|Chloroflexia	E	PFAM imidazoleglycerol-phosphate dehydratase	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
CMS1_k127_4970076_16	246197.MXAN_5465	2.171e-41	159.0	COG0454@1|root,COG0454@2|Bacteria,1RIFC@1224|Proteobacteria,42XMV@68525|delta/epsilon subdivisions,2WX09@28221|Deltaproteobacteria,2Z14Y@29|Myxococcales	28221|Deltaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7
CMS1_k127_4970076_13	1158338.JNLJ01000001_gene840	1.972e-61	218.0	COG0118@1|root,COG0118@2|Bacteria,2G3XA@200783|Aquificae	200783|Aquificae	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
CMS1_k127_4970076_11	926550.CLDAP_33900	1.049e-73	255.0	COG0106@1|root,COG0494@1|root,COG0106@2|Bacteria,COG0494@2|Bacteria,2G6EC@200795|Chloroflexi	200795|Chloroflexi	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
CMS1_k127_4970076_18	370438.PTH_1329	2.619e-27	119.0	COG0494@1|root,COG0494@2|Bacteria,1V6F5@1239|Firmicutes,24JFS@186801|Clostridia,26230@186807|Peptococcaceae	186801|Clostridia	L	pfam nudix	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
CMS1_k127_4970076_7	926550.CLDAP_33910	9.831e-107	351.0	COG0107@1|root,COG0107@2|Bacteria,2G5Y2@200795|Chloroflexi	200795|Chloroflexi	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
CMS1_k127_4970076_15	1122927.KB895424_gene2112	2.586e-44	163.0	COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,1UYNA@1239|Firmicutes,4HA9R@91061|Bacilli,26S4F@186822|Paenibacillaceae	91061|Bacilli	E	Histidine biosynthesis bifunctional protein HisIE	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS14110,iYO844.BSU34860	PRA-CH,PRA-PH
CMS1_k127_4970076_2	926550.CLDAP_33860	5.747e-178	566.0	COG0104@1|root,COG0104@2|Bacteria,2G602@200795|Chloroflexi	200795|Chloroflexi	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
CMS1_k127_4970076_24	1280673.AUJJ01000011_gene1942	5.796e-18	86.0	COG0107@1|root,COG0139@1|root,COG0140@1|root,COG0107@2|Bacteria,COG0139@2|Bacteria,COG0140@2|Bacteria,1UYNA@1239|Firmicutes,247RS@186801|Clostridia,4BXVZ@830|Butyrivibrio	186801|Clostridia	E	Phosphoribosyl-AMP cyclohydrolase	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS05760	His_biosynth,PRA-CH,PRA-PH
CMS1_k127_4970076_0	7739.XP_002591625.1	1.154e-236	745.0	COG0138@1|root,KOG2555@2759|Eukaryota,38H8U@33154|Opisthokonta,3BDGJ@33208|Metazoa,3CVFQ@33213|Bilateria,48B9G@7711|Chordata	33208|Metazoa	F	IMP cyclohydrolase activity	ATIC	GO:0003360,GO:0003674,GO:0003824,GO:0003937,GO:0004643,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006760,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009235,GO:0009259,GO:0009260,GO:0009396,GO:0009611,GO:0009987,GO:0010035,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0016742,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019238,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0021537,GO:0021543,GO:0021549,GO:0021987,GO:0022037,GO:0030900,GO:0030902,GO:0031099,GO:0031100,GO:0032501,GO:0032502,GO:0033013,GO:0034641,GO:0034654,GO:0042060,GO:0042221,GO:0042398,GO:0042558,GO:0042559,GO:0042802,GO:0042803,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046394,GO:0046452,GO:0046483,GO:0046653,GO:0046654,GO:0046983,GO:0048513,GO:0048731,GO:0048856,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0060322,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
CMS1_k127_4970076_21	136273.GY22_15995	3.165e-26	116.0	COG2227@1|root,COG2227@2|Bacteria,2IIE2@201174|Actinobacteria	201174|Actinobacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.1.1.11	ko:K03428	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R04237	RC00003,RC00460	ko00000,ko00001,ko01000	-	-	-	Methyltransf_11,Methyltransf_25
CMS1_k127_4982946_1	1207063.P24_14519	1.649e-84	292.0	COG1063@1|root,COG1063@2|Bacteria,1QTU5@1224|Proteobacteria,2TW9Q@28211|Alphaproteobacteria,2JQP9@204441|Rhodospirillales	204441|Rhodospirillales	E	Alanine dehydrogenase/PNT, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_4982946_0	1120950.KB892757_gene6491	4.637e-156	501.0	COG4948@1|root,COG4948@2|Bacteria,2GKSK@201174|Actinobacteria,4DPES@85009|Propionibacteriales	201174|Actinobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	4.2.1.156,4.2.1.42,5.5.1.27	ko:K18983,ko:K20023	ko00053,map00053	-	R05608,R10847	RC00543,RC03287	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
CMS1_k127_4982946_2	1121106.JQKB01000037_gene668	5.358e-67	231.0	COG0684@1|root,COG0684@2|Bacteria	2|Bacteria	H	ribonuclease inhibitor activity	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
CMS1_k127_4983883_7	1219084.AP014508_gene1004	3.092e-10	62.0	COG0747@1|root,COG0747@2|Bacteria,2GCNZ@200918|Thermotogae	200918|Thermotogae	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_4983883_5	1449063.JMLS01000001_gene4186	2e-49	191.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	ogl	-	4.2.2.6	ko:K01730,ko:K03641	ko00040,map00040	-	R04382	RC02124,RC02427	ko00000,ko00001,ko01000,ko02000	2.C.1.2	-	-	PD40,Pectate_lyase22
CMS1_k127_4983883_3	706587.Desti_5628	1.194e-128	421.0	COG0601@1|root,COG0601@2|Bacteria,1NS80@1224|Proteobacteria,42N5D@68525|delta/epsilon subdivisions,2WIRR@28221|Deltaproteobacteria,2MQBC@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_4983883_0	1231241.Mc24_01883	4.136e-151	486.0	COG1173@1|root,COG1173@2|Bacteria,2GCBY@200918|Thermotogae	200918|Thermotogae	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
CMS1_k127_4983883_2	1304880.JAGB01000002_gene2307	1.33e-131	428.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia	186801|Clostridia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
CMS1_k127_4983883_1	515635.Dtur_1704	3.079e-139	449.0	COG4608@1|root,COG4608@2|Bacteria	2|Bacteria	P	Belongs to the ABC transporter superfamily	gsiA_8	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
CMS1_k127_4983883_4	443143.GM18_4304	3.91e-65	234.0	COG2006@1|root,COG2006@2|Bacteria,1QMGX@1224|Proteobacteria,42PRJ@68525|delta/epsilon subdivisions,2WMFN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
CMS1_k127_4983883_6	96561.Dole_0347	4.247e-17	90.0	COG0348@1|root,COG1143@1|root,COG1245@1|root,COG0348@2|Bacteria,COG1143@2|Bacteria,COG1245@2|Bacteria,1QW0T@1224|Proteobacteria,43BQQ@68525|delta/epsilon subdivisions,2X71S@28221|Deltaproteobacteria,2MPIV@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5
CMS1_k127_4988402_2	382464.ABSI01000010_gene3494	2.126e-12	70.0	COG1063@1|root,COG1063@2|Bacteria	2|Bacteria	E	alcohol dehydrogenase	-	-	1.1.1.396	ko:K11337	ko00860,ko01110,map00860,map01110	-	R09055	RC01377	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_4988402_0	1121346.KB899812_gene2057	1.935e-302	946.0	COG1554@1|root,COG1554@2|Bacteria,1TPKN@1239|Firmicutes,4HCCF@91061|Bacilli,26QVY@186822|Paenibacillaceae	91061|Bacilli	G	alpha-L-fucosidase	-	-	3.2.1.51	ko:K15923	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	GH95	-	Glyco_hyd_65N_2
CMS1_k127_4988402_1	679937.Bcop_1988	4.948e-51	189.0	COG1387@1|root,COG1387@2|Bacteria	2|Bacteria	E	zinc ion binding	-	-	-	-	-	-	-	-	-	-	-	-	PHP
CMS1_k127_4992642_6	671143.DAMO_0935	1.204e-14	83.0	COG0673@1|root,COG0673@2|Bacteria,2NQ2X@2323|unclassified Bacteria	2|Bacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	1.1.1.335	ko:K13020	ko00520,map00520	-	R10140	RC00182	ko00000,ko00001,ko01000,ko01005	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_4992642_2	479434.Sthe_3011	7.245e-78	282.0	COG0405@1|root,COG0405@2|Bacteria,2GABC@200795|Chloroflexi,27XH8@189775|Thermomicrobia	189775|Thermomicrobia	E	TIGRFAM gamma-glutamyltransferase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
CMS1_k127_4992642_3	221288.JH992901_gene5641	3.132e-76	262.0	COG1225@1|root,COG1278@1|root,COG1225@2|Bacteria,COG1278@2|Bacteria,1GB7U@1117|Cyanobacteria,1JK51@1189|Stigonemataceae	1117|Cyanobacteria	KO	'Cold-shock' DNA-binding domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	AhpC-TSA,CSD
CMS1_k127_4992642_7	221288.JH992901_gene5641	1.271e-12	72.0	COG1225@1|root,COG1278@1|root,COG1225@2|Bacteria,COG1278@2|Bacteria,1GB7U@1117|Cyanobacteria,1JK51@1189|Stigonemataceae	1117|Cyanobacteria	KO	'Cold-shock' DNA-binding domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	AhpC-TSA,CSD
CMS1_k127_4992642_1	926550.CLDAP_32760	1.158e-171	557.0	COG0747@1|root,COG0747@2|Bacteria,2G8RA@200795|Chloroflexi	200795|Chloroflexi	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_4992642_0	1265505.ATUG01000002_gene1455	6.894e-174	564.0	COG0747@1|root,COG0747@2|Bacteria,1MUPE@1224|Proteobacteria,42QHA@68525|delta/epsilon subdivisions,2WMFT@28221|Deltaproteobacteria,2MHYN@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_4992642_4	926550.CLDAP_12130	1.509e-59	216.0	COG5551@1|root,COG5551@2|Bacteria,2G6SA@200795|Chloroflexi	200795|Chloroflexi	L	CRISPR-associated endoribonuclease Cas6	-	-	-	ko:K19091	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	CRISPR_Cas6
CMS1_k127_4992642_5	926550.CLDAP_12140	4.391e-29	117.0	COG2865@1|root,COG2865@2|Bacteria,2G8TZ@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_501342_5	338966.Ppro_1722	8.911e-06	52.0	COG4980@1|root,COG4980@2|Bacteria,1NEPD@1224|Proteobacteria,42WE2@68525|delta/epsilon subdivisions,2WRDT@28221|Deltaproteobacteria,43SRZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	YtxH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
CMS1_k127_501342_1	485913.Krac_5908	8.74e-51	185.0	COG0778@1|root,COG0778@2|Bacteria,2G7DQ@200795|Chloroflexi	200795|Chloroflexi	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CMS1_k127_501342_4	710685.MycrhN_2748	3.92e-11	66.0	COG4454@1|root,COG4454@2|Bacteria,2GS6Z@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
CMS1_k127_501342_0	525904.Tter_0222	9.547e-140	454.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2NPE1@2323|unclassified Bacteria	2|Bacteria	S	Peptidase family M50	rip3	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K06212,ko:K06402	-	-	-	-	ko00000,ko01000,ko01002,ko02000	1.A.16.1.1,1.A.16.1.3	-	-	CBS,Form_Nir_trans,Peptidase_M50
CMS1_k127_501342_3	479434.Sthe_0895	3.684e-27	115.0	COG2193@1|root,COG2193@2|Bacteria,2G6RN@200795|Chloroflexi,27YGA@189775|Thermomicrobia	189775|Thermomicrobia	P	Ferritin-like domain	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
CMS1_k127_501342_2	266117.Rxyl_0141	3.016e-46	170.0	COG1335@1|root,COG1335@2|Bacteria,2HENZ@201174|Actinobacteria,4CSAE@84995|Rubrobacteria	84995|Rubrobacteria	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
CMS1_k127_5015614_3	96561.Dole_2715	1.086e-07	55.0	COG0714@1|root,COG0714@2|Bacteria	2|Bacteria	KLT	Associated with various cellular activities	-	-	-	ko:K04748	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	AAA_5,DUF3987
CMS1_k127_5015614_1	272134.KB731324_gene2703	7.092e-126	413.0	COG1508@1|root,COG1508@2|Bacteria,1G2GU@1117|Cyanobacteria,1HA33@1150|Oscillatoriales	1117|Cyanobacteria	K	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5015614_0	383372.Rcas_0581	7.874e-218	681.0	COG0372@1|root,COG0372@2|Bacteria,2G637@200795|Chloroflexi,3765M@32061|Chloroflexia	32061|Chloroflexia	H	Belongs to the citrate synthase family	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
CMS1_k127_5015614_2	316274.Haur_4146	6.353e-112	370.0	COG0372@1|root,COG0372@2|Bacteria,2G7NR@200795|Chloroflexi,3776D@32061|Chloroflexia	32061|Chloroflexia	H	Citrate synthase, C-terminal domain	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
CMS1_k127_5020838_4	926550.CLDAP_03020	1.035e-45	179.0	COG3764@1|root,COG3764@2|Bacteria,2G70I@200795|Chloroflexi	200795|Chloroflexi	M	peptidase C60 sortase A and B	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
CMS1_k127_5020838_5	383372.Rcas_0089	3.105e-42	161.0	COG2361@1|root,COG2361@2|Bacteria,2G8W4@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
CMS1_k127_5020838_6	395961.Cyan7425_3265	9.878e-23	102.0	COG1669@1|root,COG1669@2|Bacteria,1G8HY@1117|Cyanobacteria	1117|Cyanobacteria	S	Nucleotidyltransferase domain	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
CMS1_k127_5020838_1	1089553.Tph_c25190	3.044e-103	356.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,248A3@186801|Clostridia	2|Bacteria	E	Family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_5020838_0	760568.Desku_0104	3.414e-107	356.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,260KR@186807|Peptococcaceae	186801|Clostridia	P	PFAM Binding-protein-dependent transport system inner membrane component	nikB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_5020838_3	2325.TKV_c10220	2.485e-96	323.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,42EYJ@68295|Thermoanaerobacterales	186801|Clostridia	P	ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
CMS1_k127_5020838_7	1449044.JMLE01000030_gene36	5.076e-06	51.0	2CDDX@1|root,3058G@2|Bacteria,2H42J@201174|Actinobacteria	201174|Actinobacteria	E	Alkylmercury lyase	-	-	4.99.1.2	ko:K00221	-	-	-	-	ko00000,ko01000	-	-	-	HTH_15,MerB
CMS1_k127_5021340_0	383372.Rcas_2024	1.169e-141	464.0	COG1232@1|root,COG1232@2|Bacteria,2G687@200795|Chloroflexi,375MK@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	-	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
CMS1_k127_5021340_1	1463879.JOHP01000008_gene367	2.973e-138	450.0	COG0535@1|root,COG0535@2|Bacteria,2GNSY@201174|Actinobacteria	201174|Actinobacteria	C	Radical SAM	pqqE	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
CMS1_k127_5021340_2	926550.CLDAP_19090	1.908e-100	342.0	COG0373@1|root,COG0373@2|Bacteria,2G5T4@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
CMS1_k127_5021340_5	591019.Shell_1483	1.437e-48	183.0	COG0395@1|root,arCOG00159@2157|Archaea,2XQMV@28889|Crenarchaeota	28889|Crenarchaeota	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K10198,ko:K17317	ko02010,map02010	M00203,M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.13,3.A.1.1.14,3.A.1.1.24,3.A.1.1.30	-	-	BPD_transp_1
CMS1_k127_5021340_4	768706.Desor_4702	3.833e-53	197.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,260VS@186807|Peptococcaceae	186801|Clostridia	IQ	PFAM short chain dehydrogenase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS1_k127_5021340_3	530564.Psta_3167	2.241e-94	320.0	COG0673@1|root,COG0673@2|Bacteria,2IYB5@203682|Planctomycetes	203682|Planctomycetes	S	PFAM oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_5042939_0	572477.Alvin_1360	1.363e-41	163.0	COG3267@1|root,COG3409@1|root,COG3267@2|Bacteria,COG3409@2|Bacteria,1MU3G@1224|Proteobacteria,1RMI0@1236|Gammaproteobacteria,1WWX7@135613|Chromatiales	135613|Chromatiales	U	Type II secretory pathway component ExeA	-	-	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22,PG_binding_1
CMS1_k127_5042939_3	768710.DesyoDRAFT_0002	7.881e-06	58.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,2490S@186801|Clostridia,260P2@186807|Peptococcaceae	186801|Clostridia	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
CMS1_k127_5042939_1	1123366.TH3_01405	2.332e-37	151.0	COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,2TSWH@28211|Alphaproteobacteria,2JQ3M@204441|Rhodospirillales	204441|Rhodospirillales	D	Chromosome partitioning	parA	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
CMS1_k127_5042939_2	1305737.JAFX01000001_gene283	6.256e-07	61.0	COG1475@1|root,COG1475@2|Bacteria,4NFZ9@976|Bacteroidetes,47K9I@768503|Cytophagia	976|Bacteroidetes	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
CMS1_k127_5046296_1	211165.AJLN01000040_gene6476	5.381e-114	381.0	COG0654@1|root,COG0654@2|Bacteria,1G27V@1117|Cyanobacteria,1JGY3@1189|Stigonemataceae	1117|Cyanobacteria	CH	Monooxygenase fad-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
CMS1_k127_5046296_3	521674.Plim_3648	5.702e-47	197.0	COG0515@1|root,COG0515@2|Bacteria,2IYF2@203682|Planctomycetes	203682|Planctomycetes	KLT	COG0515 Serine threonine protein	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF1080,LRR_5,Pkinase
CMS1_k127_5046296_0	338969.Rfer_2227	9.392e-189	658.0	COG0457@1|root,COG1396@1|root,COG3899@1|root,COG0457@2|Bacteria,COG1396@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2VPH8@28216|Betaproteobacteria,4AF3Y@80864|Comamonadaceae	28216|Betaproteobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD
CMS1_k127_5046296_2	926560.KE387023_gene3595	3.733e-112	412.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,1WMBC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,TPR_12
CMS1_k127_5069291_2	1089548.KI783301_gene1217	1.17e-70	259.0	COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,4H9PH@91061|Bacilli	91061|Bacilli	EH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iYO844.BSU23070	2-Hacid_dh,2-Hacid_dh_C,ACT
CMS1_k127_5069291_1	1521187.JPIM01000035_gene3396	2.72e-76	276.0	COG0617@1|root,COG0617@2|Bacteria,2G6B7@200795|Chloroflexi,376Z1@32061|Chloroflexia	32061|Chloroflexia	H	PFAM Polynucleotide adenylyltransferase region	-	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
CMS1_k127_5069291_7	903818.KI912268_gene2743	2.146e-08	64.0	COG1716@1|root,COG1716@2|Bacteria,3Y90T@57723|Acidobacteria	2|Bacteria	T	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	FHA,HTH_8,Sigma54_activat,Yop-YscD_cpl
CMS1_k127_5069291_3	316274.Haur_3169	2.912e-68	239.0	COG2208@1|root,COG2208@2|Bacteria,2G6HM@200795|Chloroflexi,375D4@32061|Chloroflexia	32061|Chloroflexia	KT	PFAM Stage II sporulation E family protein	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
CMS1_k127_5069291_4	316274.Haur_3336	2.689e-56	211.0	COG0569@1|root,COG0569@2|Bacteria	2|Bacteria	P	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2,TrkA_C,TrkA_N
CMS1_k127_5069291_6	401526.TcarDRAFT_0427	8.827e-26	111.0	COG0283@1|root,COG0283@2|Bacteria,1UK1X@1239|Firmicutes,4H9AI@909932|Negativicutes	909932|Negativicutes	F	belongs to the cytidylate kinase family. Type 1 subfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5069291_0	479434.Sthe_3518	1.068e-138	454.0	COG0215@1|root,COG0215@2|Bacteria,2G5Z0@200795|Chloroflexi,27XXR@189775|Thermomicrobia	189775|Thermomicrobia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.3.1.13	ko:K15526	-	-	-	-	ko00000,ko01000	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
CMS1_k127_5069291_5	1121405.dsmv_1613	2.882e-31	124.0	COG0618@1|root,COG0618@2|Bacteria,1N0JS@1224|Proteobacteria	1224|Proteobacteria	S	PFAM phosphoesterase, RecJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
CMS1_k127_5069635_2	652103.Rpdx1_3644	1.817e-16	79.0	COG1752@1|root,COG1752@2|Bacteria,1MUI6@1224|Proteobacteria,2U3P9@28211|Alphaproteobacteria,3JRA5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
CMS1_k127_5069635_0	402777.KB235904_gene2692	1.199e-285	889.0	COG0366@1|root,COG0366@2|Bacteria,1G0NX@1117|Cyanobacteria,1H7KE@1150|Oscillatoriales	1117|Cyanobacteria	G	Alpha amylase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,CBM_20
CMS1_k127_5069635_1	1121377.KB906399_gene1729	2.707e-185	586.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_5069635_3	979556.MTES_1043	3.206e-12	76.0	COG0524@1|root,COG0524@2|Bacteria,2GMD4@201174|Actinobacteria,4FM2B@85023|Microbacteriaceae	201174|Actinobacteria	G	pfkB family carbohydrate kinase	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
CMS1_k127_5087924_1	926569.ANT_15320	1.908e-93	323.0	COG0285@1|root,COG0285@2|Bacteria,2G64M@200795|Chloroflexi	200795|Chloroflexi	H	PFAM cytoplasmic peptidoglycan synthetase domain protein	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
CMS1_k127_5087924_0	926550.CLDAP_21420	4.3e-95	327.0	COG0457@1|root,COG0457@2|Bacteria,2G8PU@200795|Chloroflexi	200795|Chloroflexi	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
CMS1_k127_5087924_2	926550.CLDAP_01110	8.16e-34	135.0	COG0728@1|root,COG0728@2|Bacteria,2G5MD@200795|Chloroflexi	200795|Chloroflexi	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	-	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
CMS1_k127_5108476_5	926569.ANT_26780	2.814e-19	88.0	COG1247@1|root,COG1247@2|Bacteria	2|Bacteria	M	phosphinothricin N-acetyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS1_k127_5108476_3	1122917.KB899660_gene1335	2.55e-34	137.0	COG2146@1|root,COG2146@2|Bacteria,1V904@1239|Firmicutes,4HI5W@91061|Bacilli	91061|Bacilli	P	Rieske-like [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
CMS1_k127_5108476_2	1449063.JMLS01000021_gene758	7.655e-93	317.0	COG2159@1|root,COG2159@2|Bacteria,1UZAH@1239|Firmicutes,4HA5S@91061|Bacilli,26SJA@186822|Paenibacillaceae	91061|Bacilli	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CMS1_k127_5108476_0	886293.Sinac_2824	1.221e-178	567.0	COG0412@1|root,COG0412@2|Bacteria	2|Bacteria	Q	carboxymethylenebutenolidase activity	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_7,DLH,Peptidase_S9
CMS1_k127_5108476_1	1267535.KB906767_gene1478	2.56e-119	393.0	COG3173@1|root,COG3173@2|Bacteria	2|Bacteria	S	very-long-chain-acyl-CoA dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS1_k127_5108476_4	1267535.KB906767_gene1479	2.263e-27	114.0	COG0148@1|root,COG0148@2|Bacteria,3Y2IT@57723|Acidobacteria,2JI6Q@204432|Acidobacteriia	57723|Acidobacteria	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	-	-	-	-	-	-	-	-	-	-	-	-	Enolase_C,Enolase_N
CMS1_k127_5118255_10	696747.NIES39_D06370	2.644e-47	182.0	COG4372@1|root,COG4372@2|Bacteria,1G5CR@1117|Cyanobacteria,1HAQQ@1150|Oscillatoriales	1117|Cyanobacteria	S	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5118255_4	926569.ANT_13260	4.821e-128	422.0	COG0391@1|root,COG0391@2|Bacteria,2G5MJ@200795|Chloroflexi	200795|Chloroflexi	S	Required for morphogenesis under gluconeogenic growth conditions	-	-	-	-	-	-	-	-	-	-	-	-	UPF0052
CMS1_k127_5118255_2	926550.CLDAP_03680	1.481e-147	473.0	COG0057@1|root,COG0057@2|Bacteria,2G5MG@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
CMS1_k127_5118255_3	926561.KB900617_gene1889	2.711e-147	477.0	COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia,3WAD6@53433|Halanaerobiales	186801|Clostridia	G	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
CMS1_k127_5118255_8	926550.CLDAP_05540	5.061e-62	227.0	COG0726@1|root,COG0726@2|Bacteria,2G6VJ@200795|Chloroflexi	200795|Chloroflexi	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
CMS1_k127_5118255_6	459349.CLOAM0170	5.805e-81	293.0	COG0863@1|root,COG0863@2|Bacteria	2|Bacteria	L	N-4 methylation of cytosine	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase
CMS1_k127_5118255_1	926569.ANT_20890	4.91e-204	653.0	COG0465@1|root,COG0465@2|Bacteria,2G5J3@200795|Chloroflexi	200795|Chloroflexi	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
CMS1_k127_5118255_5	357808.RoseRS_3600	4.13e-88	313.0	COG1293@1|root,COG1293@2|Bacteria,2G5TC@200795|Chloroflexi,375AD@32061|Chloroflexia	32061|Chloroflexia	K	Fibronectin-binding A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
CMS1_k127_5118255_7	1173028.ANKO01000193_gene5867	3.062e-63	231.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,1G4N6@1117|Cyanobacteria	1117|Cyanobacteria	KLT	Serine Threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
CMS1_k127_5118255_11	479434.Sthe_1569	2.594e-15	79.0	COG1977@1|root,COG1977@2|Bacteria,2G9GM@200795|Chloroflexi	200795|Chloroflexi	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
CMS1_k127_5118255_0	479434.Sthe_1570	3.584e-245	762.0	COG2421@1|root,COG2421@2|Bacteria,2G88K@200795|Chloroflexi	200795|Chloroflexi	C	Acetamidase/Formamidase family	-	-	-	-	-	-	-	-	-	-	-	-	FmdA_AmdA
CMS1_k127_5118255_9	383372.Rcas_3983	5.788e-48	173.0	COG1529@1|root,COG1529@2|Bacteria,2G65D@200795|Chloroflexi,376KF@32061|Chloroflexia	32061|Chloroflexia	C	PFAM aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
CMS1_k127_5149420_1	765420.OSCT_3196	3.367e-74	258.0	COG0515@1|root,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	200795|Chloroflexi	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
CMS1_k127_5149420_0	1380394.JADL01000009_gene3136	3.209e-128	418.0	COG0111@1|root,COG0111@2|Bacteria,1NU4B@1224|Proteobacteria,2TZ0Y@28211|Alphaproteobacteria,2JVW6@204441|Rhodospirillales	204441|Rhodospirillales	EH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
CMS1_k127_5149420_2	926550.CLDAP_14740	1.044e-68	241.0	COG0639@1|root,COG0639@2|Bacteria,2G6GC@200795|Chloroflexi	200795|Chloroflexi	T	PFAM metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
CMS1_k127_5149420_4	1173027.Mic7113_4724	9.236e-36	150.0	COG3743@1|root,COG3743@2|Bacteria,1GACW@1117|Cyanobacteria,1HDG3@1150|Oscillatoriales	1117|Cyanobacteria	S	rRNA binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5149420_7	33876.JNXY01000041_gene6470	6.251e-07	57.0	2B351@1|root,31VST@2|Bacteria,2GW63@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5149420_3	649831.L083_3500	2.781e-58	222.0	COG3629@1|root,COG3629@2|Bacteria,2I5I3@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
CMS1_k127_5149420_6	136273.GY22_03740	7.273e-18	96.0	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,1W7NZ@1268|Micrococcaceae	201174|Actinobacteria	L	tyrosine recombinase	xerD	GO:0008150,GO:0040007	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
CMS1_k127_5149420_5	158190.SpiGrapes_1178	4.506e-28	124.0	COG0115@1|root,COG0115@2|Bacteria	2|Bacteria	E	branched-chain-amino-acid transaminase activity	ilvE	GO:0003674,GO:0003824,GO:0004084,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006531,GO:0006532,GO:0006551,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009098,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.21,2.6.1.42	ko:K00824,ko:K00826	ko00270,ko00280,ko00290,ko00310,ko00330,ko00360,ko00472,ko00473,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00310,map00330,map00360,map00472,map00473,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01148,R01214,R01582,R02199,R02459,R02851,R02924,R05053,R10991	RC00006,RC00008,RC00025,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iB21_1397.B21_03597,iECBD_1354.ECBD_4269,iECB_1328.ECB_03648,iECD_1391.ECD_03648,iECO103_1326.ECO103_4394	Aminotran_4
CMS1_k127_5149420_8	1265505.ATUG01000003_gene491	0.0006157	42.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42MHP@68525|delta/epsilon subdivisions,2WIQG@28221|Deltaproteobacteria,2MHMH@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	-	-	6.2.1.1,6.2.1.17	ko:K01895,ko:K01908	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
CMS1_k127_516457_0	926550.CLDAP_18560	2.36e-147	468.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
CMS1_k127_516457_1	867845.KI911784_gene362	1.29e-119	437.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	P_proprotein,Peptidase_S8,SLH,fn3
CMS1_k127_516457_3	926569.ANT_30430	1.054e-14	91.0	COG0739@1|root,COG4733@1|root,COG0739@2|Bacteria,COG4733@2|Bacteria,2G8J0@200795|Chloroflexi	200795|Chloroflexi	M	Bacterial pre-peptidase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	PPC,Peptidase_M23
CMS1_k127_516457_5	203124.Tery_0117	3.762e-08	69.0	COG1404@1|root,COG4412@1|root,COG1404@2|Bacteria,COG4412@2|Bacteria,1G04D@1117|Cyanobacteria,1H779@1150|Oscillatoriales	1117|Cyanobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,HemolysinCabind,Peptidase_S8,SdrD_B
CMS1_k127_5167839_0	1499967.BAYZ01000089_gene4997	5.541e-81	276.0	COG1943@1|root,COG1943@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
CMS1_k127_5167839_1	1379698.RBG1_1C00001G1071	2.911e-54	195.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
CMS1_k127_5180386_1	926550.CLDAP_19990	5.208e-112	374.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
CMS1_k127_5180386_2	926550.CLDAP_19980	5.537e-109	360.0	COG1175@1|root,COG1175@2|Bacteria,2G6TJ@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_5180386_3	926550.CLDAP_19970	5.846e-107	355.0	COG0395@1|root,COG0395@2|Bacteria,2G7M8@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_5180386_7	1340434.AXVA01000005_gene4820	1.132e-08	58.0	COG1396@1|root,COG1396@2|Bacteria,1VK84@1239|Firmicutes	1239|Firmicutes	K	Transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
CMS1_k127_5180386_4	316274.Haur_3833	1.105e-43	170.0	COG0789@1|root,COG4978@1|root,COG0789@2|Bacteria,COG4978@2|Bacteria	2|Bacteria	K	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like,MerR_1
CMS1_k127_5180386_5	945713.IALB_1719	7.966e-34	148.0	COG1404@1|root,COG4409@1|root,COG1404@2|Bacteria,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,CelD_N,FlgD_ig,Glyco_hydro_9,VCBS
CMS1_k127_5180386_0	761193.Runsl_0720	1.226e-123	400.0	COG1028@1|root,COG1028@2|Bacteria,4NGQY@976|Bacteroidetes,47Q3U@768503|Cytophagia	976|Bacteroidetes	IQ	KR domain	-	-	1.1.1.53	ko:K00038	ko00140,ko01100,map00140,map01100	-	R04831,R04834,R04844,R04847	RC00139,RC01219,RC01220	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
CMS1_k127_5180386_6	926550.CLDAP_19500	2.926e-26	116.0	COG0584@1|root,COG0823@1|root,COG3210@1|root,COG4886@1|root,COG0584@2|Bacteria,COG0823@2|Bacteria,COG3210@2|Bacteria,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	3.1.4.46	ko:K01126,ko:K21449	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000,ko02000	1.B.40.2	-	-	GDPD_2
CMS1_k127_5181234_0	794903.OPIT5_22740	2.4e-184	587.0	COG0383@1|root,COG0383@2|Bacteria,46Y9K@74201|Verrucomicrobia,3K96C@414999|Opitutae	414999|Opitutae	G	Alpha mannosidase, middle domain	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
CMS1_k127_5181234_2	383372.Rcas_0181	1.211e-102	345.0	COG0451@1|root,COG0451@2|Bacteria,2G87T@200795|Chloroflexi	200795|Chloroflexi	M	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
CMS1_k127_5181234_3	1499967.BAYZ01000158_gene465	2.075e-93	315.0	COG0179@1|root,COG0179@2|Bacteria,2NP4G@2323|unclassified Bacteria	2|Bacteria	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	5.3.3.10	ko:K01826	ko00350,ko01120,ko01220,map00350,map01120,map01220	M00533	R04379,R04482	RC01141,RC01162	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF2437,FAA_hydrolase
CMS1_k127_5181234_4	279714.FuraDRAFT_2532	6.143e-79	289.0	COG1306@1|root,COG1306@2|Bacteria,1MWBY@1224|Proteobacteria,2VPH9@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Putative glycosyl hydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4015
CMS1_k127_5181234_1	1128421.JAGA01000002_gene119	2.206e-145	473.0	COG0334@1|root,COG0334@2|Bacteria,2NNRJ@2323|unclassified Bacteria	2|Bacteria	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
CMS1_k127_520533_11	870187.Thini_1962	1.199e-45	181.0	COG3947@1|root,COG3947@2|Bacteria,1QDFD@1224|Proteobacteria,1SVG9@1236|Gammaproteobacteria	2|Bacteria	K	COGs COG3629 DNA-binding transcriptional activator of the SARP family	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
CMS1_k127_520533_9	192952.MM_0421	2.954e-85	293.0	COG0675@1|root,arCOG00684@2157|Archaea,2Y38N@28890|Euryarchaeota,2NAM7@224756|Methanomicrobia	224756|Methanomicrobia	L	Probable transposase	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
CMS1_k127_520533_19	472759.Nhal_0358	4.569e-08	57.0	COG0675@1|root,COG0675@2|Bacteria,1MUU0@1224|Proteobacteria,1RS1J@1236|Gammaproteobacteria,1X0FZ@135613|Chromatiales	135613|Chromatiales	L	Transposase, IS605 OrfB	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
CMS1_k127_520533_4	247634.GPB2148_239	2.155e-118	391.0	COG1062@1|root,COG1062@2|Bacteria,1MUK4@1224|Proteobacteria,1S0H1@1236|Gammaproteobacteria,1JBTT@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Zn-dependent alcohol dehydrogenases	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_520533_18	1123288.SOV_2c06210	3.833e-08	54.0	COG1051@1|root,COG1051@2|Bacteria,1V7E6@1239|Firmicutes,4H4XZ@909932|Negativicutes	909932|Negativicutes	F	Hydrolase, NUDIX family	-	-	3.6.1.55,3.6.1.56	ko:K03574,ko:K17816	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
CMS1_k127_520533_8	765420.OSCT_2658	8.49e-98	329.0	COG0491@1|root,COG0491@2|Bacteria,2G7QF@200795|Chloroflexi,375EQ@32061|Chloroflexia	32061|Chloroflexia	S	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS1_k127_520533_13	706587.Desti_0717	5.462e-19	92.0	COG0466@1|root,COG0466@2|Bacteria,1R6HF@1224|Proteobacteria,42QHZ@68525|delta/epsilon subdivisions,2WJNZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Response regulator receiver	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,Lon_C,Response_reg
CMS1_k127_520533_3	1123501.KB902276_gene1401	1.223e-144	481.0	COG0395@1|root,COG1175@1|root,COG0395@2|Bacteria,COG1175@2|Bacteria,1N4I0@1224|Proteobacteria,2TT14@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	ABC-type sugar transport system, permease component	MA20_03550	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_520533_5	926560.KE387027_gene789	2.587e-114	394.0	COG0739@1|root,COG0739@2|Bacteria,1WM9M@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CMS1_k127_520533_14	1121403.AUCV01000006_gene415	5.942e-19	101.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,42NVA@68525|delta/epsilon subdivisions,2WMQK@28221|Deltaproteobacteria,2MHTJ@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
CMS1_k127_520533_7	765420.OSCT_0805	6.612e-101	342.0	COG0577@1|root,COG0577@2|Bacteria,2G65B@200795|Chloroflexi,37660@32061|Chloroflexia	32061|Chloroflexia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS1_k127_520533_10	292459.STH976	4.867e-84	286.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia	186801|Clostridia	V	ABC transporter	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_520533_12	926550.CLDAP_04490	6.999e-27	125.0	COG0823@1|root,COG3103@1|root,COG0823@2|Bacteria,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	NLPC_P60,Rick_17kDa_Anti,SH3_3
CMS1_k127_520533_20	1128421.JAGA01000003_gene3538	8.045e-08	56.0	COG2353@1|root,COG2353@2|Bacteria,2NR1J@2323|unclassified Bacteria	2|Bacteria	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
CMS1_k127_520533_0	1499967.BAYZ01000151_gene1666	7.976e-182	587.0	COG1132@1|root,COG1132@2|Bacteria,2NNP8@2323|unclassified Bacteria	2|Bacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS1_k127_520533_1	1499967.BAYZ01000151_gene1665	1.252e-163	535.0	COG1132@1|root,COG1132@2|Bacteria,2NP2M@2323|unclassified Bacteria	2|Bacteria	V	ABC transporter transmembrane region	yfiB	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS1_k127_520533_16	1395516.PMO01_18740	1.178e-09	65.0	COG1846@1|root,COG1846@2|Bacteria,1RH1F@1224|Proteobacteria,1S8WM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Transcriptional regulator	ohrR	-	-	-	-	-	-	-	-	-	-	-	MarR
CMS1_k127_520533_6	1128421.JAGA01000003_gene3537	2.932e-107	351.0	COG0745@1|root,COG0745@2|Bacteria,2NPCK@2323|unclassified Bacteria	2|Bacteria	T	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_520533_2	1128421.JAGA01000003_gene3536	3.057e-146	479.0	COG5002@1|root,COG5002@2|Bacteria,2NS5D@2323|unclassified Bacteria	2|Bacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K02484,ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
CMS1_k127_520533_15	118173.KB235914_gene2547	8.308e-17	82.0	COG1476@1|root,COG1476@2|Bacteria,1GFFE@1117|Cyanobacteria,1HG93@1150|Oscillatoriales	1117|Cyanobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
CMS1_k127_521106_2	479434.Sthe_3135	1.623e-74	267.0	COG1721@1|root,COG1721@2|Bacteria,2G6Y7@200795|Chloroflexi,27Y3Z@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CMS1_k127_521106_5	717785.HYPMC_3215	2.745e-56	202.0	COG2940@1|root,COG2940@2|Bacteria,1NEA4@1224|Proteobacteria,2VGQI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain	-	-	-	-	-	-	-	-	-	-	-	-	SET
CMS1_k127_521106_6	479434.Sthe_1631	3.119e-52	200.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_521106_8	67356.KL575627_gene3471	9.378e-10	70.0	COG5635@1|root,COG5635@2|Bacteria,2GNCH@201174|Actinobacteria	201174|Actinobacteria	T	Signal transduction protein with Nacht domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4062,HEAT_2,NACHT
CMS1_k127_521106_4	67356.KL575627_gene3470	2.265e-64	247.0	COG1192@1|root,COG1672@1|root,COG1192@2|Bacteria,COG1672@2|Bacteria,2I39W@201174|Actinobacteria	201174|Actinobacteria	K	Involved in chromosome partitioning	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,HTH_31,Trypsin_2
CMS1_k127_521106_9	313606.M23134_08363	9.381e-09	69.0	COG0457@1|root,COG2208@1|root,COG0457@2|Bacteria,COG2208@2|Bacteria,4NP26@976|Bacteroidetes,47XH9@768503|Cytophagia	976|Bacteroidetes	T	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_10,TPR_12,TPR_8
CMS1_k127_521106_3	525904.Tter_2643	4.952e-65	243.0	2APCB@1|root,31EEJ@2|Bacteria,2NRJG@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF4129)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
CMS1_k127_521106_1	525904.Tter_2276	8.308e-103	347.0	COG1721@1|root,COG1721@2|Bacteria,2NR5R@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CMS1_k127_521106_0	525904.Tter_2275	3.537e-137	444.0	COG0714@1|root,COG0714@2|Bacteria,2NNMQ@2323|unclassified Bacteria	2|Bacteria	S	ATPase associated with various cellular	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS1_k127_521106_7	1242864.D187_009937	5.744e-30	129.0	COG1741@1|root,COG1741@2|Bacteria,1MVSW@1224|Proteobacteria,42T87@68525|delta/epsilon subdivisions,2WP52@28221|Deltaproteobacteria,2YURQ@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
CMS1_k127_521570_5	1382356.JQMP01000003_gene2180	3.762e-49	180.0	COG1974@1|root,COG1974@2|Bacteria,2G6NC@200795|Chloroflexi,27Y6E@189775|Thermomicrobia	189775|Thermomicrobia	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
CMS1_k127_521570_0	867903.ThesuDRAFT_02019	2.194e-257	814.0	COG1529@1|root,COG1529@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,3WD5H@538999|Clostridiales incertae sedis	186801|Clostridia	C	Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead domain	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
CMS1_k127_521570_1	1128421.JAGA01000002_gene1517	3.132e-165	529.0	COG3844@1|root,COG3844@2|Bacteria,2NS52@2323|unclassified Bacteria	2|Bacteria	E	Aminotransferase class-V	kynU	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016822,GO:0016823,GO:0019439,GO:0019441,GO:0019752,GO:0030429,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
CMS1_k127_521570_7	1321778.HMPREF1982_03143	2.381e-08	66.0	COG3745@1|root,COG3745@2|Bacteria,1V5FZ@1239|Firmicutes,24I7V@186801|Clostridia	186801|Clostridia	U	Flp pilus assembly protein CpaB	-	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	LysM,RcpC,SAF
CMS1_k127_521570_6	675816.VIA_000956	5.841e-42	165.0	COG0697@1|root,COG0697@2|Bacteria,1R46X@1224|Proteobacteria,1RYTA@1236|Gammaproteobacteria,1Y27F@135623|Vibrionales	135623|Vibrionales	EG	of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS1_k127_521570_2	1197477.IA57_09655	4.406e-104	347.0	COG0451@1|root,COG0451@2|Bacteria,4NEKA@976|Bacteroidetes,1HY26@117743|Flavobacteriia	976|Bacteroidetes	M	epimerase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,GDP_Man_Dehyd
CMS1_k127_521570_4	1121378.KB899704_gene2420	5.126e-57	203.0	COG2132@1|root,COG2132@2|Bacteria,1WJQI@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2,Cu-oxidase_3
CMS1_k127_5223184_21	911045.PSE_3895	1.437e-12	67.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,2TQP8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
CMS1_k127_5223184_9	926550.CLDAP_04110	4.328e-49	176.0	COG0051@1|root,COG0051@2|Bacteria,2G6RB@200795|Chloroflexi	200795|Chloroflexi	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
CMS1_k127_5223184_1	326427.Cagg_3024	7.868e-82	278.0	COG0087@1|root,COG0087@2|Bacteria,2G6DQ@200795|Chloroflexi,375C3@32061|Chloroflexia	32061|Chloroflexia	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
CMS1_k127_5223184_5	316274.Haur_4916	2.824e-64	226.0	COG0088@1|root,COG0088@2|Bacteria,2G6K2@200795|Chloroflexi,374Y7@32061|Chloroflexia	32061|Chloroflexia	J	Forms part of the polypeptide exit tunnel	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
CMS1_k127_5223184_19	1051632.TPY_0325	9.377e-19	89.0	COG0089@1|root,COG0089@2|Bacteria,1VA4W@1239|Firmicutes,24MN8@186801|Clostridia,3WDFR@538999|Clostridiales incertae sedis	186801|Clostridia	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
CMS1_k127_5223184_0	926550.CLDAP_04070	3.626e-135	434.0	COG0090@1|root,COG0090@2|Bacteria,2G65E@200795|Chloroflexi	200795|Chloroflexi	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
CMS1_k127_5223184_12	926569.ANT_10080	4.363e-43	158.0	COG0185@1|root,COG0185@2|Bacteria,2G6US@200795|Chloroflexi	200795|Chloroflexi	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
CMS1_k127_5223184_15	1125779.HMPREF1219_02241	8.912e-27	113.0	COG0091@1|root,COG0091@2|Bacteria,2IM3J@201174|Actinobacteria,22N5U@1653|Corynebacteriaceae	201174|Actinobacteria	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
CMS1_k127_5223184_3	1521187.JPIM01000007_gene1387	1.116e-73	255.0	COG0092@1|root,COG0092@2|Bacteria,2G691@200795|Chloroflexi,3757R@32061|Chloroflexia	32061|Chloroflexia	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
CMS1_k127_5223184_6	111780.Sta7437_4095	6.108e-62	215.0	COG0197@1|root,COG0197@2|Bacteria,1G55B@1117|Cyanobacteria,3VJMQ@52604|Pleurocapsales	1117|Cyanobacteria	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
CMS1_k127_5223184_22	1514668.JOOA01000002_gene1970	9.717e-11	64.0	COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes,24QV1@186801|Clostridia,3WKVV@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
CMS1_k127_5223184_16	1111479.AXAR01000008_gene2349	1.509e-25	108.0	COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,4HKDN@91061|Bacilli,27A6H@186823|Alicyclobacillaceae	91061|Bacilli	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
CMS1_k127_5223184_8	266940.Krad_0698	7.297e-55	195.0	COG0093@1|root,COG0093@2|Bacteria,2IHNX@201174|Actinobacteria	201174|Actinobacteria	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071944,GO:0097159,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
CMS1_k127_5223184_14	771875.Ferpe_1405	1.42e-29	121.0	COG0198@1|root,COG0198@2|Bacteria,2GD31@200918|Thermotogae	200918|Thermotogae	J	One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
CMS1_k127_5223184_2	926550.CLDAP_03980	8.364e-82	275.0	COG0094@1|root,COG0094@2|Bacteria,2G6C6@200795|Chloroflexi	200795|Chloroflexi	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
CMS1_k127_5223184_17	926569.ANT_10170	8.191e-25	104.0	COG0199@1|root,COG0199@2|Bacteria,2G74J@200795|Chloroflexi	200795|Chloroflexi	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
CMS1_k127_5223184_10	383372.Rcas_4012	3.005e-45	167.0	COG0096@1|root,COG0096@2|Bacteria,2G6XS@200795|Chloroflexi,375RI@32061|Chloroflexia	32061|Chloroflexia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
CMS1_k127_5223184_4	796606.BMMGA3_00770	1.016e-67	234.0	COG0097@1|root,COG0097@2|Bacteria,1V1FC@1239|Firmicutes,4HFQD@91061|Bacilli,1ZCR5@1386|Bacillus	91061|Bacilli	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
CMS1_k127_5223184_11	926550.CLDAP_03940	3.118e-43	160.0	COG0256@1|root,COG0256@2|Bacteria,2G6Y4@200795|Chloroflexi	200795|Chloroflexi	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
CMS1_k127_5223184_7	926550.CLDAP_03930	1.834e-61	216.0	COG0098@1|root,COG0098@2|Bacteria,2G6M9@200795|Chloroflexi	200795|Chloroflexi	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
CMS1_k127_5223184_20	246194.CHY_2291	8.313e-16	79.0	COG1841@1|root,COG1841@2|Bacteria,1VEG4@1239|Firmicutes,24QKC@186801|Clostridia,42HG7@68295|Thermoanaerobacterales	186801|Clostridia	J	Ribosomal protein L30	rpmD	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
CMS1_k127_5223184_13	1034345.CAEM01000014_gene182	4.802e-42	159.0	COG0200@1|root,COG0200@2|Bacteria,2II6M@201174|Actinobacteria,4CVMS@84998|Coriobacteriia	84998|Coriobacteriia	J	binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
CMS1_k127_5223184_18	1540221.JQNI01000002_gene2845	2.285e-23	102.0	COG0201@1|root,COG0201@2|Bacteria,1WIJP@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
CMS1_k127_524500_3	324602.Caur_1344	5.222e-69	244.0	COG0682@1|root,COG0682@2|Bacteria,2G6QJ@200795|Chloroflexi	200795|Chloroflexi	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
CMS1_k127_524500_2	1128421.JAGA01000001_gene2121	4.712e-69	241.0	COG0569@1|root,COG0569@2|Bacteria,2NPKV@2323|unclassified Bacteria	2|Bacteria	P	TrkA-N domain	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
CMS1_k127_524500_1	1128421.JAGA01000001_gene2120	1.749e-118	396.0	COG0168@1|root,COG0168@2|Bacteria,2NNW1@2323|unclassified Bacteria	2|Bacteria	P	Cation transport protein	trkG	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
CMS1_k127_524500_0	880073.Calab_1860	4.307e-253	801.0	COG2183@1|root,COG2183@2|Bacteria,2NP2S@2323|unclassified Bacteria	2|Bacteria	K	Tex-like protein N-terminal domain	yhgF	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0044424,GO:0044444,GO:0044464,GO:0050896	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
CMS1_k127_524500_5	1173264.KI913949_gene761	9.685e-36	141.0	COG3007@1|root,COG3007@2|Bacteria	2|Bacteria	I	enoyl-[acyl-carrier-protein] reductase (NADH) activity	fabV	GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050343,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.3.1.44,1.3.1.9	ko:K00209	ko00061,ko00650,ko01100,ko01120,ko01200,ko01212,map00061,map00650,map01100,map01120,map01200,map01212	M00083	R01171,R04429,R04724,R04955,R04958,R04961,R04966,R04969	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Eno-Rase_FAD_bd,Eno-Rase_NADH_b,Enoyl_reductase
CMS1_k127_524500_6	391612.CY0110_27415	4.2e-34	135.0	COG1708@1|root,COG1708@2|Bacteria,1GAR8@1117|Cyanobacteria	1117|Cyanobacteria	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_524500_4	118173.KB235914_gene3652	2.124e-62	219.0	2DGVE@1|root,32U82@2|Bacteria,1G87Z@1117|Cyanobacteria,1HDAU@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_524500_7	1041147.AUFB01000001_gene4399	9.44e-26	111.0	COG1082@1|root,COG1082@2|Bacteria,1PJT1@1224|Proteobacteria,2VE23@28211|Alphaproteobacteria,4BCWJ@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
CMS1_k127_5246303_8	439235.Dalk_1475	1.242e-11	77.0	COG1470@1|root,COG4733@1|root,COG1470@2|Bacteria,COG4733@2|Bacteria,1QW0V@1224|Proteobacteria,42U6C@68525|delta/epsilon subdivisions,2WQX8@28221|Deltaproteobacteria,2MN90@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_3_2,DUF4215
CMS1_k127_5246303_4	324602.Caur_1283	1.009e-102	346.0	COG0438@1|root,COG0438@2|Bacteria,2G5PS@200795|Chloroflexi,375CY@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS1_k127_5246303_1	926550.CLDAP_04540	6.122e-148	486.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,2G66B@200795|Chloroflexi	200795|Chloroflexi	M	PFAM sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
CMS1_k127_5246303_2	926569.ANT_05010	6.206e-111	367.0	COG1234@1|root,COG1234@2|Bacteria,2G6YW@200795|Chloroflexi	200795|Chloroflexi	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
CMS1_k127_5246303_5	471852.Tcur_3197	4.155e-61	223.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4EHK1@85012|Streptosporangiales	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
CMS1_k127_5246303_0	926569.ANT_16550	1.305e-153	491.0	COG0451@1|root,COG0451@2|Bacteria,2G8B1@200795|Chloroflexi	200795|Chloroflexi	GM	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
CMS1_k127_5246303_7	765420.OSCT_0497	6.594e-27	118.0	2DPX2@1|root,333RW@2|Bacteria,2G7A0@200795|Chloroflexi,377B3@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function (DUF4013)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4013
CMS1_k127_5246303_6	926569.ANT_23560	7.182e-46	171.0	2DM5T@1|root,31U0Y@2|Bacteria,2G78W@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF4126)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4126
CMS1_k127_5246303_3	552811.Dehly_0095	7.592e-105	349.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2G5J0@200795|Chloroflexi,34CQM@301297|Dehalococcoidia	301297|Dehalococcoidia	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
CMS1_k127_5247289_12	485913.Krac_2635	3.066e-43	162.0	COG0457@1|root,COG3629@1|root,COG3899@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG3899@2|Bacteria,2G871@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,TPR_12
CMS1_k127_5247289_1	316274.Haur_3791	4.47e-201	636.0	COG0004@1|root,COG0004@2|Bacteria,2G5N8@200795|Chloroflexi,3753U@32061|Chloroflexia	32061|Chloroflexia	P	PFAM Rh family protein ammonium transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
CMS1_k127_5247289_14	42256.RradSPS_2994	1.05e-31	132.0	COG1309@1|root,COG1309@2|Bacteria,2GRIJ@201174|Actinobacteria,4CQMX@84995|Rubrobacteria	84995|Rubrobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS1_k127_5247289_13	523841.HFX_1807	2.286e-41	158.0	COG0492@1|root,arCOG01301@2157|Archaea,2XUTM@28890|Euryarchaeota,23S44@183963|Halobacteria	183963|Halobacteria	O	FAD-dependent pyridine nucleotide-disulfide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
CMS1_k127_5247289_5	644966.Tmar_0143	8.353e-89	302.0	COG5322@1|root,COG5322@2|Bacteria,1TQ2E@1239|Firmicutes,24A1Y@186801|Clostridia	186801|Clostridia	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5247289_0	926550.CLDAP_02700	1.363e-286	892.0	COG0296@1|root,COG0296@2|Bacteria,2G5IR@200795|Chloroflexi	200795|Chloroflexi	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
CMS1_k127_5247289_4	926569.ANT_19910	2.019e-99	334.0	COG3407@1|root,COG3407@2|Bacteria,2G5SQ@200795|Chloroflexi	200795|Chloroflexi	I	GHMP kinases N terminal domain	mvaD	-	4.1.1.33	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095	R01121	RC00453	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_N
CMS1_k127_5247289_16	1117644.MCANPG14_00938	3.519e-07	59.0	COG3557@1|root,COG3557@2|Bacteria,3WTPJ@544448|Tenericutes	544448|Tenericutes	J	domain protein associated with RNAses G and E	-	-	-	ko:K07586	-	-	-	-	ko00000	-	-	-	DUF402
CMS1_k127_5247289_7	525904.Tter_1708	6.975e-85	289.0	COG1606@1|root,COG1606@2|Bacteria,2NP5T@2323|unclassified Bacteria	2|Bacteria	L	tRNA processing	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	Asn_synthase,NAD_synthase
CMS1_k127_5247289_8	1122947.FR7_3519	1.808e-80	276.0	COG1691@1|root,COG1691@2|Bacteria,1TP0Z@1239|Firmicutes,4H25Y@909932|Negativicutes	909932|Negativicutes	S	AIR carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
CMS1_k127_5247289_3	240016.ABIZ01000001_gene502	6.745e-120	396.0	COG1641@1|root,COG1641@2|Bacteria,46THK@74201|Verrucomicrobia,2IUEA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes	larC	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
CMS1_k127_5247289_9	926550.CLDAP_05590	1.59e-62	231.0	COG0750@1|root,COG0750@2|Bacteria,2G6GY@200795|Chloroflexi	200795|Chloroflexi	M	SMART PDZ DHR GLGF domain protein	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
CMS1_k127_5247289_17	926550.CLDAP_01420	0.0009532	50.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	ratA	-	-	-	-	-	-	-	-	-	-	-	DUF823,DUF824,LysM,NLPC_P60,SH3_3
CMS1_k127_5247289_10	383372.Rcas_1417	3.535e-49	188.0	COG1413@1|root,COG1413@2|Bacteria,2G6MW@200795|Chloroflexi,375QB@32061|Chloroflexia	32061|Chloroflexia	C	PBS lyase HEAT domain protein repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
CMS1_k127_5247289_11	926550.CLDAP_39600	5.837e-47	180.0	COG0539@1|root,COG0539@2|Bacteria,2G90B@200795|Chloroflexi	200795|Chloroflexi	J	PFAM RNA binding S1 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	S1
CMS1_k127_5247289_2	926550.CLDAP_24880	2.651e-157	505.0	COG0468@1|root,COG0468@2|Bacteria,2G5WE@200795|Chloroflexi	200795|Chloroflexi	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
CMS1_k127_5247289_15	357808.RoseRS_1462	1.688e-24	109.0	COG1716@1|root,COG1716@2|Bacteria,2G9CS@200795|Chloroflexi,375YC@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA
CMS1_k127_5247518_4	306281.AJLK01000062_gene4978	1.885e-68	235.0	COG0399@1|root,COG0399@2|Bacteria,1G0IM@1117|Cyanobacteria,1JJ7R@1189|Stigonemataceae	1117|Cyanobacteria	M	Cys/Met metabolism PLP-dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
CMS1_k127_5247518_3	1170562.Cal6303_3090	1.352e-112	367.0	COG0110@1|root,COG0110@2|Bacteria,1GBCV@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Bacterial transferase hexapeptide (three repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
CMS1_k127_5247518_1	306281.AJLK01000062_gene4976	5.381e-166	526.0	COG0451@1|root,COG0451@2|Bacteria,1G44E@1117|Cyanobacteria,1JKD8@1189|Stigonemataceae	1117|Cyanobacteria	M	Male sterility protein	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
CMS1_k127_5247518_0	98439.AJLL01000028_gene4246	5.277e-204	640.0	COG0399@1|root,COG0399@2|Bacteria,1G5FI@1117|Cyanobacteria	1117|Cyanobacteria	E	COGs COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
CMS1_k127_5247518_2	1173024.KI912149_gene4994	3.506e-144	468.0	COG0463@1|root,COG0463@2|Bacteria,1G03Y@1117|Cyanobacteria,1JM6G@1189|Stigonemataceae	1117|Cyanobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS1_k127_5301552_2	1214101.BN159_6249	1.414e-28	132.0	COG1075@1|root,COG1075@2|Bacteria,2I090@201174|Actinobacteria	201174|Actinobacteria	S	Lecithin:cholesterol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	LCAT
CMS1_k127_5301552_3	383372.Rcas_3609	1.552e-20	106.0	COG0842@1|root,COG1131@1|root,COG1716@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,COG1716@2|Bacteria,2G7J8@200795|Chloroflexi,374RZ@32061|Chloroflexia	32061|Chloroflexia	V	ABC transporter related	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC_tran,FHA
CMS1_k127_5301552_0	264198.Reut_B4834	7.329e-115	410.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2VKH1@28216|Betaproteobacteria,1JZT2@119060|Burkholderiaceae	28216|Betaproteobacteria	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
CMS1_k127_5301552_1	1487953.JMKF01000089_gene5400	1.018e-32	149.0	COG3629@1|root,COG5635@1|root,COG3629@2|Bacteria,COG5635@2|Bacteria,1G14T@1117|Cyanobacteria,1H8RF@1150|Oscillatoriales	1117|Cyanobacteria	T	Ntpase (Nacht family)	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	NACHT,Pkinase,TIR_2
CMS1_k127_5341785_0	1499967.BAYZ01000019_gene6268	4.736e-202	638.0	COG1026@1|root,COG1026@2|Bacteria,2NQI2@2323|unclassified Bacteria	2|Bacteria	S	Peptidase M16C associated	CP_0875	-	-	ko:K06972	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M16C_assoc,Peptidase_M16,Peptidase_M16_C
CMS1_k127_5341785_4	1205910.B005_1613	3.941e-06	55.0	COG0454@1|root,COG0456@2|Bacteria,2IQSU@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS1_k127_5341785_3	383372.Rcas_0271	2.467e-06	50.0	2E9PK@1|root,333W0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4258
CMS1_k127_5341785_2	926550.CLDAP_21940	2.863e-28	115.0	COG5428@1|root,COG5428@2|Bacteria,2G9DH@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF2283)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2283
CMS1_k127_5341785_1	421072.IO89_06265	4.584e-46	173.0	COG4403@1|root,COG4403@2|Bacteria,4PKR3@976|Bacteroidetes,1I295@117743|Flavobacteriia,3HIJ4@358033|Chryseobacterium	976|Bacteroidetes	V	Lanthionine synthetase C family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_536151_6	1352941.M877_37060	2.011e-39	160.0	COG0451@1|root,COG0451@2|Bacteria,2GP24@201174|Actinobacteria	201174|Actinobacteria	M	Epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
CMS1_k127_536151_2	525904.Tter_1977	3.089e-137	441.0	COG2141@1|root,COG2141@2|Bacteria,2NQXW@2323|unclassified Bacteria	2|Bacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS1_k127_536151_5	1502724.FF80_01708	5.254e-83	296.0	COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,2TVAC@28211|Alphaproteobacteria,3N82X@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
CMS1_k127_536151_1	357808.RoseRS_2272	1.024e-220	699.0	COG1132@1|root,COG1132@2|Bacteria,2G7J5@200795|Chloroflexi,3758C@32061|Chloroflexia	32061|Chloroflexia	V	PFAM ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS1_k127_536151_0	357808.RoseRS_2270	1.15e-253	795.0	COG1132@1|root,COG1132@2|Bacteria,2G7QN@200795|Chloroflexi,374U2@32061|Chloroflexia	32061|Chloroflexia	V	PFAM ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
CMS1_k127_536151_4	1185876.BN8_00710	6.369e-100	337.0	COG2382@1|root,COG2382@2|Bacteria,4NFVV@976|Bacteroidetes,47PFY@768503|Cytophagia	976|Bacteroidetes	P	Belongs to the glycosyl hydrolase 13 family	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	CBM_48,Esterase
CMS1_k127_536151_3	886293.Sinac_2763	9.591e-112	372.0	COG2382@1|root,COG2382@2|Bacteria,2IYMZ@203682|Planctomycetes	203682|Planctomycetes	P	Putative esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase
CMS1_k127_5387719_1	1313172.YM304_36100	5.379e-145	469.0	COG0045@1|root,COG0045@2|Bacteria,2GKSB@201174|Actinobacteria,4CMVM@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
CMS1_k127_5387719_2	525909.Afer_0320	5.475e-131	424.0	COG0074@1|root,COG0074@2|Bacteria,2GK00@201174|Actinobacteria,4CMSK@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
CMS1_k127_5387719_0	1173027.Mic7113_5927	1.966e-224	710.0	COG5002@1|root,COG5002@2|Bacteria,1G4FM@1117|Cyanobacteria,1HH4Y@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_4
CMS1_k127_5387719_3	1173027.Mic7113_0944	1.417e-86	291.0	COG2204@1|root,COG2204@2|Bacteria,1G623@1117|Cyanobacteria,1HFTT@1150|Oscillatoriales	1117|Cyanobacteria	T	Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,TPR_8
CMS1_k127_5387719_4	1382306.JNIM01000001_gene1032	1.574e-42	158.0	COG1529@1|root,COG1529@2|Bacteria,2G65D@200795|Chloroflexi	200795|Chloroflexi	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
CMS1_k127_5401832_3	383372.Rcas_4390	1.538e-30	124.0	COG1420@1|root,COG1420@2|Bacteria,2G6AQ@200795|Chloroflexi,374VS@32061|Chloroflexia	32061|Chloroflexia	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA
CMS1_k127_5401832_4	926550.CLDAP_31430	4.343e-24	111.0	COG0576@1|root,COG0576@2|Bacteria,2G77I@200795|Chloroflexi	200795|Chloroflexi	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
CMS1_k127_5401832_0	926569.ANT_25050	3.215e-275	859.0	COG0443@1|root,COG0443@2|Bacteria,2G5U5@200795|Chloroflexi	200795|Chloroflexi	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
CMS1_k127_5401832_1	398767.Glov_2828	2.188e-114	380.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,42KZM@68525|delta/epsilon subdivisions,2WJGP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
CMS1_k127_5401832_2	926550.CLDAP_11360	3.548e-63	227.0	COG2264@1|root,COG2264@2|Bacteria,2G69X@200795|Chloroflexi	200795|Chloroflexi	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
CMS1_k127_5406280_3	266779.Meso_4489	7.137e-142	457.0	COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,2TQTV@28211|Alphaproteobacteria,43HF5@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
CMS1_k127_5406280_4	266779.Meso_4488	3.701e-128	418.0	COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,2TR0J@28211|Alphaproteobacteria,43IM6@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	EP	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
CMS1_k127_5406280_1	266779.Meso_4487	1.363e-170	543.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,2TUWG@28211|Alphaproteobacteria,43R5I@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
CMS1_k127_5406280_2	1380394.JADL01000001_gene2216	6.534e-142	457.0	COG0601@1|root,COG0601@2|Bacteria,1MWXF@1224|Proteobacteria,2TR7C@28211|Alphaproteobacteria,2JQ7B@204441|Rhodospirillales	204441|Rhodospirillales	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_5406280_0	1380394.JADL01000001_gene2217	5.253e-209	671.0	COG0747@1|root,COG0747@2|Bacteria,1MU3P@1224|Proteobacteria,2TT4M@28211|Alphaproteobacteria,2JQRE@204441|Rhodospirillales	204441|Rhodospirillales	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_5411158_3	321332.CYB_1018	1.383e-88	299.0	COG2103@1|root,COG2103@2|Bacteria,1G1DR@1117|Cyanobacteria,1GYHZ@1129|Synechococcus	1117|Cyanobacteria	H	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate	murQ	-	4.2.1.126	ko:K07106	ko00520,ko01100,map00520,map01100	-	R08555	RC00397,RC00746	ko00000,ko00001,ko01000	-	-	-	SIS,SIS_2
CMS1_k127_5411158_7	1123023.JIAI01000003_gene2772	9.481e-52	190.0	COG0684@1|root,COG0684@2|Bacteria,2IP83@201174|Actinobacteria	201174|Actinobacteria	H	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
CMS1_k127_5411158_2	316274.Haur_4664	5.68e-96	329.0	COG0642@1|root,COG2205@2|Bacteria,2GBIY@200795|Chloroflexi	200795|Chloroflexi	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
CMS1_k127_5411158_4	66429.JOFL01000006_gene1998	2.288e-75	259.0	COG0745@1|root,COG0745@2|Bacteria,2GK5S@201174|Actinobacteria	201174|Actinobacteria	T	response regulator, receiver	resD	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_5411158_9	1341181.FLJC2902T_25080	1.703e-27	130.0	COG0823@1|root,COG0823@2|Bacteria,4NG4S@976|Bacteroidetes,1I1I2@117743|Flavobacteriia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
CMS1_k127_5411158_5	926550.CLDAP_29640	1.744e-55	218.0	COG3664@1|root,COG3664@2|Bacteria,2GBKT@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycoside hydrolase family 39	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5411158_1	326427.Cagg_2272	3.074e-118	391.0	COG0263@1|root,COG0263@2|Bacteria,2G67X@200795|Chloroflexi,3757K@32061|Chloroflexia	32061|Chloroflexia	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
CMS1_k127_5411158_6	316274.Haur_4101	1.083e-54	205.0	COG5530@1|root,COG5530@2|Bacteria	2|Bacteria	S	Predicted integral membrane protein (DUF2270)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2270
CMS1_k127_5411158_10	580327.Tthe_1965	5.926e-12	77.0	COG1284@1|root,COG1284@2|Bacteria,1TRAU@1239|Firmicutes,249DE@186801|Clostridia,42FZ6@68295|Thermoanaerobacterales	186801|Clostridia	S	Uncharacterised 5xTM membrane BCR, YitT family COG1284	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
CMS1_k127_5411158_0	926569.ANT_12200	1.063e-145	473.0	COG0014@1|root,COG0014@2|Bacteria,2G5TY@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS1_k127_5411158_8	266117.Rxyl_0489	5.561e-36	140.0	COG2135@1|root,COG2135@2|Bacteria,2GKY8@201174|Actinobacteria,4CQI8@84995|Rubrobacteria	84995|Rubrobacteria	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
CMS1_k127_5413302_2	1499689.CCNN01000007_gene865	3.316e-66	243.0	COG1680@1|root,COG1680@2|Bacteria,1TRPT@1239|Firmicutes,2495H@186801|Clostridia,36WDR@31979|Clostridiaceae	186801|Clostridia	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,Beta-lactamase,DUF302
CMS1_k127_5413302_0	1499967.BAYZ01000153_gene1548	6.734e-112	372.0	COG1672@1|root,COG1672@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AAA_13,AAA_22,AAA_35,PDDEXK_9
CMS1_k127_5413302_1	765910.MARPU_00280	1.361e-108	366.0	COG1055@1|root,COG1055@2|Bacteria,1MUX4@1224|Proteobacteria,1RMAV@1236|Gammaproteobacteria,1WZAK@135613|Chromatiales	135613|Chromatiales	U	Involved in arsenical resistance. Thought to form the channel of an arsenite pump	arsB	-	-	ko:K03893	-	-	-	-	ko00000,ko02000	2.A.45.1,3.A.4.1	-	-	ArsB
CMS1_k127_5413302_3	1408422.JHYF01000003_gene819	3.84e-12	72.0	COG0517@1|root,COG0517@2|Bacteria,1VA1X@1239|Firmicutes,24MNT@186801|Clostridia,36KWH@31979|Clostridiaceae	186801|Clostridia	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
CMS1_k127_5413302_4	697281.Mahau_0245	2.62e-09	68.0	COG0347@1|root,COG0347@2|Bacteria,1TTXT@1239|Firmicutes,25K0U@186801|Clostridia,42IT2@68295|Thermoanaerobacterales	186801|Clostridia	E	Belongs to the P(II) protein family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5416687_1	926550.CLDAP_25950	3.018e-98	325.0	COG1045@1|root,COG1045@2|Bacteria,2G6DI@200795|Chloroflexi	200795|Chloroflexi	E	TIGRFAM serine O-acetyltransferase	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
CMS1_k127_5416687_0	926550.CLDAP_20110	1.302e-158	504.0	COG0031@1|root,COG0031@2|Bacteria,2G5PG@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS1_k127_5416687_2	272558.10175365	3.561e-39	149.0	COG1742@1|root,COG1742@2|Bacteria,1V6YJ@1239|Firmicutes,4HIIY@91061|Bacilli,1ZHH6@1386|Bacillus	91061|Bacilli	S	UPF0060 membrane protein	yfjF	-	-	ko:K09771	-	-	-	-	ko00000,ko02000	2.A.7.26	-	-	UPF0060
CMS1_k127_5418345_4	926550.CLDAP_38780	1.114e-11	70.0	COG4249@1|root,COG4249@2|Bacteria,2G8EH@200795|Chloroflexi	200795|Chloroflexi	S	Peptidase C14 caspase catalytic subunit p20	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5418345_0	1121396.KB893056_gene2642	1.424e-58	210.0	COG4783@1|root,COG4783@2|Bacteria,1P1GF@1224|Proteobacteria	1224|Proteobacteria	S	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5418345_3	1267535.KB906767_gene4822	4.133e-30	124.0	COG1848@1|root,COG1848@2|Bacteria	2|Bacteria	G	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN,PIN_3
CMS1_k127_5418345_5	1123234.AUKI01000024_gene2188	1.469e-06	53.0	2DMNP@1|root,32SQ4@2|Bacteria,4NT2A@976|Bacteroidetes,1I3Z7@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5418345_1	1123508.JH636443_gene4610	3.97e-54	197.0	2AP53@1|root,31E6R@2|Bacteria,2J31B@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5418345_2	1128421.JAGA01000001_gene2454	1.483e-34	143.0	COG0745@1|root,COG0745@2|Bacteria,2NQZN@2323|unclassified Bacteria	2|Bacteria	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_5424129_0	765420.OSCT_1712	1.137e-85	308.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G8GW@200795|Chloroflexi,3776B@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
CMS1_k127_5424129_1	1121451.DESAM_22149	6.458e-75	259.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42Q40@68525|delta/epsilon subdivisions,2WKYI@28221|Deltaproteobacteria,2MA7Y@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	response regulator, receiver	-	-	-	ko:K02479	-	-	-	-	ko00000,ko02022	-	-	-	GerE,Response_reg
CMS1_k127_5424129_3	648757.Rvan_3194	1.711e-34	134.0	COG0599@1|root,COG0599@2|Bacteria,1N2A3@1224|Proteobacteria,2UC3T@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS1_k127_5424129_2	926560.KE387023_gene2407	3.534e-64	223.0	COG1832@1|root,COG1832@2|Bacteria	2|Bacteria	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
CMS1_k127_5428855_17	99598.Cal7507_5430	1.155e-05	48.0	COG0864@1|root,COG0864@2|Bacteria,1GAJD@1117|Cyanobacteria,1HTMI@1161|Nostocales	1117|Cyanobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5428855_8	555779.Dthio_PD3795	8.04e-48	173.0	COG2337@1|root,COG2337@2|Bacteria,1MYU1@1224|Proteobacteria,42UNN@68525|delta/epsilon subdivisions,2WQA2@28221|Deltaproteobacteria,2MFFM@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	Toxic component of a toxin-antitoxin (TA) module	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
CMS1_k127_5428855_4	504472.Slin_3912	3.655e-93	310.0	COG1434@1|root,COG1434@2|Bacteria,4NI3S@976|Bacteroidetes,47NUZ@768503|Cytophagia	976|Bacteroidetes	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
CMS1_k127_5428855_7	1519464.HY22_11450	2.347e-53	195.0	COG5135@1|root,COG5135@2|Bacteria	2|Bacteria	S	pyridoxal 5'-phosphate salvage	-	-	1.1.1.31,1.4.3.5	ko:K00020,ko:K00275	ko00280,ko00750,ko01100,ko01120,map00280,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711,R05066	RC00048,RC00099,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	Putative_PNPOx,Pyridox_oxase_2
CMS1_k127_5428855_14	926569.ANT_22190	9.832e-13	81.0	COG1572@1|root,COG1572@2|Bacteria,2G9M8@200795|Chloroflexi	2|Bacteria	S	Ig-like domain from next to BRCA1 gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,N_BRCA1_IG
CMS1_k127_5428855_16	471854.Dfer_0264	1.353e-08	67.0	COG4733@1|root,COG4733@2|Bacteria,4NK2V@976|Bacteroidetes,47P6C@768503|Cytophagia	976|Bacteroidetes	G	PFAM Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
CMS1_k127_5428855_15	1121430.JMLG01000006_gene1729	2.757e-12	80.0	COG1716@1|root,COG1716@2|Bacteria,1V5U0@1239|Firmicutes,24IDE@186801|Clostridia,261TT@186807|Peptococcaceae	186801|Clostridia	T	(FHA) domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3662,Yop-YscD_cpl
CMS1_k127_5428855_10	760568.Desku_1317	2.486e-21	101.0	COG1716@1|root,COG1716@2|Bacteria,1V5U0@1239|Firmicutes,24IDE@186801|Clostridia,261TT@186807|Peptococcaceae	186801|Clostridia	T	(FHA) domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3662,Yop-YscD_cpl
CMS1_k127_5428855_18	243090.RB12202	0.0008989	42.0	COG0582@1|root,COG0582@2|Bacteria,2J2X9@203682|Planctomycetes	203682|Planctomycetes	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
CMS1_k127_5428855_6	926550.CLDAP_04400	3.264e-84	284.0	COG0745@1|root,COG0745@2|Bacteria,2G5TG@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07669	ko02020,map02020	M00460	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_5428855_2	357808.RoseRS_2057	2.099e-99	341.0	COG2770@1|root,COG5002@1|root,COG2770@2|Bacteria,COG5002@2|Bacteria,2G68T@200795|Chloroflexi,375B4@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
CMS1_k127_5428855_0	926569.ANT_10550	8.539e-171	550.0	COG0769@1|root,COG0769@2|Bacteria,2G5U3@200795|Chloroflexi	200795|Chloroflexi	M	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS1_k127_5428855_13	1042877.GQS_04320	1.501e-13	86.0	COG1361@1|root,COG1404@1|root,arCOG03610@1|root,arCOG00704@2157|Archaea,arCOG02089@2157|Archaea,arCOG03610@2157|Archaea,2XV8N@28890|Euryarchaeota,243CT@183968|Thermococci	183968|Thermococci	O	Belongs to the peptidase S8 family	pls	GO:0005575,GO:0005623,GO:0031975,GO:0044464	-	-	-	-	-	-	-	-	-	-	CARDB,PPC,Peptidase_S8
CMS1_k127_5428855_3	1347087.CBYO010000016_gene2628	6.911e-99	365.0	COG1404@1|root,COG1520@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Inhibitor_I9,PQQ_2,PQQ_3,Peptidase_S8
CMS1_k127_5428855_12	1463855.JOHV01000002_gene2474	6.872e-14	76.0	COG1734@1|root,COG1734@2|Bacteria,2GJBE@201174|Actinobacteria	201174|Actinobacteria	T	Transcriptional regulator, TraR DksA family	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
CMS1_k127_5428855_1	926550.CLDAP_02580	3.173e-135	441.0	COG2255@1|root,COG2255@2|Bacteria,2G5QQ@200795|Chloroflexi	200795|Chloroflexi	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
CMS1_k127_5428855_9	1449063.JMLS01000001_gene4455	3.033e-34	142.0	COG0500@1|root,COG2226@2|Bacteria,1VIXJ@1239|Firmicutes,4HGT9@91061|Bacilli,277H6@186822|Paenibacillaceae	91061|Bacilli	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
CMS1_k127_5428855_11	1128421.JAGA01000002_gene1596	9.582e-16	79.0	29Y14@1|root,30JU1@2|Bacteria,2NRYB@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function (DUF2905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2905
CMS1_k127_5428855_5	926569.ANT_19880	3.31e-85	289.0	COG0809@1|root,COG0809@2|Bacteria,2G5UZ@200795|Chloroflexi	200795|Chloroflexi	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
CMS1_k127_5430790_2	765420.OSCT_0542	3.405e-57	203.0	COG1104@1|root,COG1104@2|Bacteria,2G63V@200795|Chloroflexi,3751V@32061|Chloroflexia	32061|Chloroflexia	E	aromatic amino acid beta-eliminating lyase threonine aldolase	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
CMS1_k127_5430790_1	926569.ANT_01810	5.984e-79	275.0	COG0673@1|root,COG0673@2|Bacteria,2G8FU@200795|Chloroflexi	200795|Chloroflexi	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_5430790_0	1033743.CAES01000098_gene2690	2.196e-96	324.0	COG2124@1|root,COG2124@2|Bacteria,1TPWZ@1239|Firmicutes,4HAGS@91061|Bacilli,26V2H@186822|Paenibacillaceae	91061|Bacilli	Q	cytochrome P450	bioI	GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.14.14.46	ko:K16593	ko00780,ko01100,map00780,map01100	M00573	R10123	-	ko00000,ko00001,ko00002,ko00199,ko01000	-	-	-	p450
CMS1_k127_5436092_3	709797.CSIRO_0066	3.846e-20	96.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2TSTW@28211|Alphaproteobacteria,3JVAX@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	EH	Thiamine pyrophosphate enzyme, central domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS1_k127_5436092_0	1347086.CCBA010000025_gene3148	9.36e-54	201.0	COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,4HA59@91061|Bacilli,1ZDWB@1386|Bacillus	91061|Bacilli	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
CMS1_k127_5436092_1	1227500.C494_08257	1.638e-52	195.0	COG1028@1|root,arCOG01259@2157|Archaea,2XVZM@28890|Euryarchaeota,23UKP@183963|Halobacteria	183963|Halobacteria	I	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS1_k127_5436092_2	411464.DESPIG_01769	1.867e-44	177.0	COG2271@1|root,COG2271@2|Bacteria,1QU9E@1224|Proteobacteria,43CQZ@68525|delta/epsilon subdivisions,2WNBR@28221|Deltaproteobacteria,2MA0B@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	Major Facilitator Superfamily	-	-	-	ko:K08223	-	-	-	-	ko00000,ko02000	2.A.1.35	-	-	MFS_1
CMS1_k127_5436092_4	485914.Hmuk_0322	6.021e-09	65.0	COG0673@1|root,arCOG01622@2157|Archaea,2XV19@28890|Euryarchaeota,23V24@183963|Halobacteria	183963|Halobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_5441236_4	1318628.MARLIPOL_09971	1.535e-10	72.0	COG1372@1|root,COG1520@1|root,COG3209@1|root,COG1372@2|Bacteria,COG1520@2|Bacteria,COG3209@2|Bacteria,1QW4H@1224|Proteobacteria,1T42N@1236|Gammaproteobacteria,46DDZ@72275|Alteromonadaceae	1236|Gammaproteobacteria	LM	Rhs Family	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,DUF5122,He_PIG,PT-HINT,RHS_repeat
CMS1_k127_5441236_1	1288963.ADIS_1161	2.329e-93	317.0	COG0667@1|root,COG0667@2|Bacteria,4NEB0@976|Bacteroidetes,47XEA@768503|Cytophagia	976|Bacteroidetes	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS1_k127_5441236_0	234267.Acid_5780	7.556e-95	353.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria	2|Bacteria	T	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,BTAD,TPR_12,TPR_8,Trans_reg_C
CMS1_k127_5441236_3	1121447.JONL01000001_gene404	3.03e-63	250.0	COG1235@1|root,COG1235@2|Bacteria,1NW4Z@1224|Proteobacteria,42PTI@68525|delta/epsilon subdivisions,2WIWT@28221|Deltaproteobacteria,2M93E@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
CMS1_k127_5441236_2	697282.Mettu_1373	2.736e-71	251.0	COG0647@1|root,COG0647@2|Bacteria,1QGX4@1224|Proteobacteria,1RRS1@1236|Gammaproteobacteria,1XE4Z@135618|Methylococcales	135618|Methylococcales	G	Belongs to the HAD-like hydrolase superfamily	-	-	3.1.3.41	ko:K01101	ko00627,ko01120,map00627,map01120	-	R03024	RC00151	ko00000,ko00001,ko01000	-	-	-	Hydrolase_6,Hydrolase_like
CMS1_k127_5444486_2	338963.Pcar_0628	1.937e-99	328.0	COG2513@1|root,COG2513@2|Bacteria,1N4VT@1224|Proteobacteria,42PWB@68525|delta/epsilon subdivisions,2X5K5@28221|Deltaproteobacteria,43VRB@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Phosphoenolpyruvate phosphomutase	-	-	5.4.2.9	ko:K01841	ko00440,ko01100,ko01120,ko01130,map00440,map01100,map01120,map01130	-	R00661	RC02792	ko00000,ko00001,ko01000	-	-	-	CTP_transf_like,NTP_transf_3,PEP_mutase
CMS1_k127_5444486_0	338966.Ppro_2168	2.213e-164	526.0	COG3919@1|root,COG3919@2|Bacteria,1N13P@1224|Proteobacteria,42WGT@68525|delta/epsilon subdivisions,2WRKR@28221|Deltaproteobacteria,43VRY@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_3
CMS1_k127_5444486_7	1280666.ATVS01000030_gene1624	5.332e-27	119.0	COG1285@1|root,COG1285@2|Bacteria,1TRUW@1239|Firmicutes,248G4@186801|Clostridia,4BY2S@830|Butyrivibrio	186801|Clostridia	S	Domain of unknown function (DUF4956)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
CMS1_k127_5444486_8	555088.DealDRAFT_0821	1.651e-21	104.0	COG5036@1|root,COG5036@2|Bacteria	2|Bacteria	P	cellular response to phosphate starvation	-	-	-	-	-	-	-	-	-	-	-	-	VTC
CMS1_k127_5444486_9	1366046.HIMB11_00410	6.98e-17	96.0	COG5337@1|root,COG5337@2|Bacteria,1QX5G@1224|Proteobacteria,2TZQE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH
CMS1_k127_5444486_5	272562.CA_C3056	2.677e-51	192.0	COG1208@1|root,COG1208@2|Bacteria,1VDBC@1239|Firmicutes,24AGU@186801|Clostridia,36UK6@31979|Clostridiaceae	186801|Clostridia	GJM	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	gmhB	-	2.7.7.13,2.7.7.71,3.1.3.82,3.1.3.83,5.4.2.8	ko:K00966,ko:K03273,ko:K15669,ko:K16881	ko00051,ko00520,ko00540,ko01100,ko01110,ko01130,map00051,map00520,map00540,map01100,map01110,map01130	M00064,M00114,M00361,M00362	R00885,R01818,R05647,R09771,R09772	RC00002,RC00017,RC00408	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hydrolase_like,NTP_transferase,PNK3P
CMS1_k127_5444486_1	592015.HMPREF1705_00545	4.526e-138	450.0	COG2605@1|root,COG2605@2|Bacteria,3TC8T@508458|Synergistetes	508458|Synergistetes	S	GHMP kinases C terminal	-	-	2.7.1.168	ko:K07031	ko00540,map00540	-	R09770	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
CMS1_k127_5444486_3	383372.Rcas_3096	2.104e-59	213.0	COG0279@1|root,COG0279@2|Bacteria,2G6QD@200795|Chloroflexi,375VE@32061|Chloroflexia	32061|Chloroflexia	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
CMS1_k127_5444486_4	1123242.JH636434_gene4144	3.55e-56	203.0	COG0241@1|root,COG0241@2|Bacteria,2IZYR@203682|Planctomycetes	203682|Planctomycetes	E	Polynucleotide kinase 3 phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_like
CMS1_k127_5444486_10	1125863.JAFN01000001_gene2260	6.835e-07	61.0	COG3420@1|root,COG3420@2|Bacteria,1Q48B@1224|Proteobacteria,42YK2@68525|delta/epsilon subdivisions,2WUN5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
CMS1_k127_5444486_6	46234.ANA_C10381	4.736e-40	164.0	COG0438@1|root,COG0438@2|Bacteria,1G0TI@1117|Cyanobacteria,1HKVT@1161|Nostocales	1117|Cyanobacteria	M	SPTR Glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
CMS1_k127_5458208_5	357808.RoseRS_0252	8.599e-78	283.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G8F9@200795|Chloroflexi,374XW@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA_3
CMS1_k127_5458208_9	1177154.Y5S_03661	1.461e-38	155.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
CMS1_k127_5458208_12	1273538.G159_19045	8.262e-08	57.0	COG0667@1|root,COG0667@2|Bacteria,1TQJC@1239|Firmicutes,4HC0W@91061|Bacilli,26EPP@186818|Planococcaceae	91061|Bacilli	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS1_k127_5458208_10	794903.OPIT5_14435	1.939e-34	138.0	COG4770@1|root,COG4770@2|Bacteria	2|Bacteria	I	CoA carboxylase activity	pccA	-	6.4.1.3	ko:K01965,ko:K02160	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00373,M00376,M00741	R00742,R01859	RC00040,RC00097,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
CMS1_k127_5458208_2	926550.CLDAP_21630	1.978e-182	584.0	COG0439@1|root,COG0439@2|Bacteria,2G62X@200795|Chloroflexi	200795|Chloroflexi	I	Carbamoyl-phosphate synthetase large chain domain protein	accC	-	6.3.4.14,6.4.1.2,6.4.1.3,6.4.1.4	ko:K01961,ko:K01968,ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00036,M00082,M00376,M00741	R00742,R01859,R04138,R04385	RC00040,RC00097,RC00253,RC00367,RC00609,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
CMS1_k127_5458208_1	382464.ABSI01000010_gene3728	1.874e-241	756.0	COG4799@1|root,COG4799@2|Bacteria	2|Bacteria	I	CoA carboxylase activity	pccB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0031974,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0070013,GO:0071704,GO:0072329,GO:1901575	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
CMS1_k127_5458208_3	1128421.JAGA01000003_gene3228	8.747e-101	338.0	COG0604@1|root,COG0604@2|Bacteria,2NP5I@2323|unclassified Bacteria	2|Bacteria	C	PFAM Alcohol dehydrogenase, zinc-binding	-	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_5458208_6	926569.ANT_15670	1.259e-69	263.0	COG0642@1|root,COG2205@2|Bacteria	926569.ANT_15670|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5458208_4	1128421.JAGA01000002_gene375	8.532e-87	292.0	COG2003@1|root,COG2003@2|Bacteria,2NPI9@2323|unclassified Bacteria	2|Bacteria	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
CMS1_k127_5458208_11	1265505.ATUG01000001_gene4622	2.366e-34	139.0	COG1051@1|root,COG1051@2|Bacteria,1MWNH@1224|Proteobacteria,42T59@68525|delta/epsilon subdivisions,2WPMV@28221|Deltaproteobacteria,2MKE0@213118|Desulfobacterales	28221|Deltaproteobacteria	F	NUDIX domain	-	-	3.6.1.13,3.6.1.55	ko:K01515,ko:K03574	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000,ko03400	-	-	-	NUDIX
CMS1_k127_5458208_0	926550.CLDAP_18760	5.879e-273	851.0	COG0529@1|root,COG2046@1|root,COG0529@2|Bacteria,COG2046@2|Bacteria,2G7JD@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the synthesis of activated sulfate	cysC	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,ATP-sulfurylase,PUA_2
CMS1_k127_5458208_8	1313172.YM304_13720	4.952e-51	209.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Big_2,CBM26,CBM_25,Calx-beta,DUF4114,P_proprotein,Peptidase_S8,SBBP,SLH,VCBS
CMS1_k127_5458208_7	755732.Fluta_3353	1.52e-63	249.0	COG5184@1|root,COG5184@2|Bacteria,4PKDT@976|Bacteroidetes	976|Bacteroidetes	DZ	M6 family metalloprotease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
CMS1_k127_5458433_0	1128421.JAGA01000003_gene3678	2.684e-74	272.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2NQCZ@2323|unclassified Bacteria	2|Bacteria	K	NB-ARC domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_22,BTAD,NB-ARC,TPR_10,TPR_12,TPR_8,Trans_reg_C
CMS1_k127_5458433_1	316274.Haur_2320	4.088e-47	177.0	COG1670@1|root,COG1670@2|Bacteria,2G9NS@200795|Chloroflexi	200795|Chloroflexi	J	COGs COG1670 Acetyltransferase including N-acetylase of ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
CMS1_k127_5458433_3	1382306.JNIM01000001_gene1518	2.085e-15	90.0	COG0515@1|root,COG1672@1|root,COG0515@2|Bacteria,COG1672@2|Bacteria,2G8HW@200795|Chloroflexi	200795|Chloroflexi	KLT	Peptidase C14 caspase catalytic subunit p20	-	-	-	-	-	-	-	-	-	-	-	-	WD40
CMS1_k127_5458433_2	370438.PTH_1394	1e-43	175.0	COG1414@1|root,COG3598@1|root,COG1414@2|Bacteria,COG3598@2|Bacteria,1TU5N@1239|Firmicutes,247KK@186801|Clostridia,265S3@186807|Peptococcaceae	186801|Clostridia	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_25
CMS1_k127_5458433_4	1249627.D779_1417	0.0001492	49.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,1S2PN@1236|Gammaproteobacteria,1WYNY@135613|Chromatiales	135613|Chromatiales	KLT	PFAM Sulphatase-modifying factor	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PEGA,PG_binding_1,Pkinase
CMS1_k127_5458541_0	926550.CLDAP_04130	5.854e-304	945.0	COG0480@1|root,COG0480@2|Bacteria,2G63B@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
CMS1_k127_5458541_1	649638.Trad_0655	1.076e-59	223.0	COG2271@1|root,COG2271@2|Bacteria	2|Bacteria	G	transmembrane transporter activity	-	-	-	ko:K05820	-	-	-	-	ko00000,ko02000	2.A.1.27	-	-	MFS_1
CMS1_k127_5458541_3	373903.Hore_06870	1.904e-30	124.0	COG3877@1|root,COG3877@2|Bacteria,1VAFG@1239|Firmicutes,24MSP@186801|Clostridia,3WC2X@53433|Halanaerobiales	186801|Clostridia	S	Protein of unknown function (DUF2089)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2089
CMS1_k127_5475436_4	880073.Calab_2864	7.035e-91	312.0	COG0389@1|root,COG0389@2|Bacteria,2NP5S@2323|unclassified Bacteria	2|Bacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
CMS1_k127_5475436_7	1122919.KB905548_gene2293	6.58e-61	220.0	COG3393@1|root,COG3393@2|Bacteria,1TRN7@1239|Firmicutes,4IGDW@91061|Bacilli,2717Q@186822|Paenibacillaceae	91061|Bacilli	S	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	GNAT_acetyltran
CMS1_k127_5475436_5	926569.ANT_01810	1.765e-81	282.0	COG0673@1|root,COG0673@2|Bacteria,2G8FU@200795|Chloroflexi	200795|Chloroflexi	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_5475436_8	323259.Mhun_1757	1.927e-50	186.0	COG1394@1|root,arCOG04101@2157|Archaea	2157|Archaea	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpD	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
CMS1_k127_5475436_1	1041930.Mtc_2333	1.21e-200	636.0	COG1156@1|root,arCOG00865@2157|Archaea,2XSYQ@28890|Euryarchaeota,2NAB4@224756|Methanomicrobia	224756|Methanomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit	atpB-2	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
CMS1_k127_5475436_0	1499689.CCNN01000006_gene486	1.449e-209	669.0	COG1155@1|root,COG1155@2|Bacteria,1TPGS@1239|Firmicutes,24882@186801|Clostridia,36DW7@31979|Clostridiaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit	atpA	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
CMS1_k127_5475436_12	42256.RradSPS_2938	3.37e-16	83.0	COG1436@1|root,COG1436@2|Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpF	-	-	ko:K02122	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_F
CMS1_k127_5475436_10	304371.MCP_2288	3.047e-47	183.0	COG1527@1|root,arCOG02459@2157|Archaea,2XTK5@28890|Euryarchaeota,2NAIS@224756|Methanomicrobia	224756|Methanomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC-2	-	-	ko:K02119	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_AC39
CMS1_k127_5475436_13	45157.CMQ010CT	0.0001844	51.0	COG1390@1|root,KOG1664@2759|Eukaryota	2759|Eukaryota	C	proton-transporting ATPase activity, rotational mechanism	ATP6V1E1	GO:0000003,GO:0000041,GO:0000221,GO:0000322,GO:0000323,GO:0000324,GO:0000325,GO:0000329,GO:0000331,GO:0001669,GO:0001763,GO:0002009,GO:0003006,GO:0003674,GO:0003735,GO:0003824,GO:0005198,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005773,GO:0005774,GO:0005794,GO:0005829,GO:0005840,GO:0005844,GO:0005886,GO:0005902,GO:0006810,GO:0006811,GO:0006812,GO:0006826,GO:0006873,GO:0006885,GO:0006950,GO:0006952,GO:0006970,GO:0006996,GO:0007030,GO:0007035,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0007275,GO:0007424,GO:0007430,GO:0008104,GO:0008150,GO:0008286,GO:0008324,GO:0008553,GO:0009266,GO:0009409,GO:0009605,GO:0009607,GO:0009617,GO:0009628,GO:0009651,GO:0009653,GO:0009705,GO:0009719,GO:0009725,GO:0009735,GO:0009790,GO:0009791,GO:0009793,GO:0009832,GO:0009888,GO:0009894,GO:0009987,GO:0010033,GO:0010154,GO:0010243,GO:0010256,GO:0010506,GO:0012505,GO:0015031,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0015682,GO:0015833,GO:0015988,GO:0015991,GO:0016020,GO:0016021,GO:0016043,GO:0016241,GO:0016324,GO:0016462,GO:0016469,GO:0016471,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019222,GO:0019725,GO:0019829,GO:0019899,GO:0022414,GO:0022626,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0023052,GO:0030001,GO:0030003,GO:0030004,GO:0030139,GO:0030141,GO:0030641,GO:0031090,GO:0031164,GO:0031224,GO:0031323,GO:0031329,GO:0031410,GO:0031982,GO:0032501,GO:0032502,GO:0032868,GO:0032869,GO:0032870,GO:0032991,GO:0033036,GO:0033176,GO:0033178,GO:0033180,GO:0033181,GO:0033572,GO:0034220,GO:0035239,GO:0035295,GO:0036442,GO:0042221,GO:0042546,GO:0042592,GO:0042623,GO:0042625,GO:0042626,GO:0042742,GO:0042788,GO:0042886,GO:0042995,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043434,GO:0043492,GO:0044085,GO:0044422,GO:0044424,GO:0044425,GO:0044433,GO:0044437,GO:0044444,GO:0044445,GO:0044446,GO:0044459,GO:0044464,GO:0044769,GO:0044877,GO:0045176,GO:0045177,GO:0045184,GO:0045851,GO:0046961,GO:0048316,GO:0048608,GO:0048729,GO:0048731,GO:0048754,GO:0048856,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051117,GO:0051179,GO:0051234,GO:0051452,GO:0051453,GO:0051704,GO:0051707,GO:0051716,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0060429,GO:0060446,GO:0060541,GO:0060562,GO:0061138,GO:0061458,GO:0065007,GO:0065008,GO:0070887,GO:0071310,GO:0071375,GO:0071417,GO:0071495,GO:0071554,GO:0071669,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072512,GO:0090662,GO:0097223,GO:0097708,GO:0098542,GO:0098588,GO:0098590,GO:0098655,GO:0098660,GO:0098662,GO:0098771,GO:0098796,GO:0098797,GO:0098805,GO:0098852,GO:0098858,GO:0099131,GO:0099132,GO:0099503,GO:0120025,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902600,GO:1990904	-	ko:K02150	ko00190,ko01100,ko04145,ko04150,ko04721,ko04966,ko05110,ko05120,ko05323,map00190,map01100,map04145,map04150,map04721,map04966,map05110,map05120,map05323	M00160	-	-	ko00000,ko00001,ko00002	3.A.2.2	-	-	vATP-synt_E
CMS1_k127_5475436_11	42256.RradSPS_2941	3.046e-22	97.0	COG0636@1|root,COG0636@2|Bacteria	2|Bacteria	C	ATP hydrolysis coupled proton transport	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110,ko:K02124	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157,M00159	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1,3.A.2.2,3.A.2.3	-	-	ATP-synt_C
CMS1_k127_5475436_2	323259.Mhun_1764	2.435e-111	383.0	COG1269@1|root,arCOG04138@2157|Archaea,2XTQP@28890|Euryarchaeota	28890|Euryarchaeota	C	Belongs to the V-ATPase 116 kDa subunit family	atpI-2	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
CMS1_k127_5475436_6	1382356.JQMP01000001_gene939	5.727e-71	252.0	COG1609@1|root,COG1609@2|Bacteria,2G6CQ@200795|Chloroflexi	200795|Chloroflexi	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
CMS1_k127_5475436_3	1459636.NTE_00534	3.309e-110	364.0	COG2070@1|root,arCOG00635@2157|Archaea	2157|Archaea	S	2-nitropropane dioxygenase	npd	-	1.13.12.16,1.3.1.9	ko:K00459,ko:K02371	ko00061,ko00910,ko01100,ko01212,map00061,map00910,map01100,map01212	M00083	R00025,R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076,RC02541,RC02759	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	NMO
CMS1_k127_5475436_9	251221.35211658	5.197e-50	182.0	COG3629@1|root,COG3629@2|Bacteria	2|Bacteria	K	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,NB-ARC,TPR_10,TPR_12,Trans_reg_C
CMS1_k127_5481534_1	1122919.KB905552_gene590	4.224e-238	743.0	COG1486@1|root,COG1486@2|Bacteria,1TQ9I@1239|Firmicutes,4HBV7@91061|Bacilli,275E9@186822|Paenibacillaceae	91061|Bacilli	G	alpha-galactosidase	melA7	-	3.2.1.22	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_4,Glyco_hydro_4C
CMS1_k127_5481534_0	926550.CLDAP_14400	4.175e-306	954.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,2G65R@200795|Chloroflexi	200795|Chloroflexi	C	malic protein domain protein	-	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_4,Malic_M,malic
CMS1_k127_5486613_3	1499967.BAYZ01000103_gene3718	4.925e-44	163.0	COG1028@1|root,COG1028@2|Bacteria,2NQZI@2323|unclassified Bacteria	2|Bacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS1_k127_5486613_0	926550.CLDAP_26040	3.196e-174	553.0	COG0673@1|root,COG0673@2|Bacteria,2G5VF@200795|Chloroflexi	2|Bacteria	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_5486613_1	926550.CLDAP_26150	8.755e-104	347.0	COG0673@1|root,COG0673@2|Bacteria,2G6E7@200795|Chloroflexi	2|Bacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	iolG	-	1.1.1.18,1.1.1.369	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	-	R01183,R09951	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_5486613_2	926550.CLDAP_26060	2.063e-95	317.0	COG1129@1|root,COG1129@2|Bacteria	2|Bacteria	G	ABC transporter	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
CMS1_k127_5491293_1	196490.AUEZ01000001_gene7530	6.175e-122	396.0	COG2159@1|root,COG2159@2|Bacteria,1R73N@1224|Proteobacteria	1224|Proteobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
CMS1_k127_5491293_3	525904.Tter_0291	1.238e-60	227.0	COG1508@1|root,COG1508@2|Bacteria,2NNZA@2323|unclassified Bacteria	2|Bacteria	K	RNA polymerase sigma-54 factor	rpoN	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0042802,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
CMS1_k127_5491293_0	105559.Nwat_0326	2.294e-155	503.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,1RMHY@1236|Gammaproteobacteria,1X2ND@135613|Chromatiales	135613|Chromatiales	KT	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	ko:K10941	ko02020,ko02025,ko05111,map02020,map02025,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_8,Sigma54_activat
CMS1_k127_5491293_2	266117.Rxyl_0547	2.835e-96	325.0	COG4948@1|root,COG4948@2|Bacteria,2GT81@201174|Actinobacteria,4CT8G@84995|Rubrobacteria	84995|Rubrobacteria	M	PFAM Mandelate racemase muconate lactonizing	-	-	4.2.1.6	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R03033	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
CMS1_k127_5499290_0	1502724.FF80_03561	4.702e-122	405.0	COG4225@1|root,COG4225@2|Bacteria,1N5V1@1224|Proteobacteria,2UTQQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Heparinase II/III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III
CMS1_k127_5499290_1	926550.CLDAP_12690	7.015e-66	229.0	COG3059@1|root,COG3059@2|Bacteria	2|Bacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF417,DoxX
CMS1_k127_5499290_4	926569.ANT_28790	2.458e-08	59.0	COG1545@1|root,COG1545@2|Bacteria,2G73Z@200795|Chloroflexi	200795|Chloroflexi	S	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
CMS1_k127_5499290_2	880072.Desac_1530	1.769e-48	182.0	COG0584@1|root,COG0584@2|Bacteria,1MU8H@1224|Proteobacteria,42U7W@68525|delta/epsilon subdivisions,2X29N@28221|Deltaproteobacteria,2MSB3@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM Glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
CMS1_k127_5499290_3	1449126.JQKL01000019_gene3249	3.918e-48	188.0	COG1063@1|root,COG1063@2|Bacteria,1U91N@1239|Firmicutes,24ARB@186801|Clostridia	186801|Clostridia	E	Zinc-binding dehydrogenase	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_5500033_1	1304880.JAGB01000002_gene2156	1.55e-71	246.0	COG0433@1|root,COG0433@2|Bacteria,1UD3Y@1239|Firmicutes,24DTE@186801|Clostridia	186801|Clostridia	S	Domain of unknown function DUF87	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF87
CMS1_k127_5500033_2	1173021.ALWA01000035_gene3699	1.256e-22	99.0	COG2319@1|root,COG3903@1|root,COG2319@2|Bacteria,COG3903@2|Bacteria,1FZVW@1117|Cyanobacteria	1117|Cyanobacteria	A	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC,WD40
CMS1_k127_5500033_0	1382356.JQMP01000001_gene704	1.118e-198	639.0	COG1529@1|root,COG1529@2|Bacteria,2G65D@200795|Chloroflexi,27Y2Q@189775|Thermomicrobia	189775|Thermomicrobia	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
CMS1_k127_5509552_5	479434.Sthe_3331	1.128e-09	61.0	2BVHN@1|root,32SWN@2|Bacteria,2G8ZV@200795|Chloroflexi	200795|Chloroflexi	S	Pfam:DUF385	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
CMS1_k127_5509552_3	489825.LYNGBM3L_53820	5.619e-46	168.0	COG0073@1|root,COG0073@2|Bacteria	2|Bacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10,6.1.1.20,6.1.1.6	ko:K01874,ko:K01890,ko:K04566,ko:K06878	ko00450,ko00970,map00450,map00970	M00359,M00360	R03658,R03659,R03660,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,B5,tRNA-synt_1f,tRNA-synt_1g,tRNA_bind
CMS1_k127_5509552_4	1396141.BATP01000058_gene1970	2.109e-24	114.0	COG0558@1|root,COG0558@2|Bacteria,46VXY@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5509552_0	247639.MGP2080_02126	1.46e-112	374.0	COG1062@1|root,COG1062@2|Bacteria,1MUK4@1224|Proteobacteria,1S0H1@1236|Gammaproteobacteria,1JBTT@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Zn-dependent alcohol dehydrogenases	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_5509552_2	1463885.KL578420_gene2111	9.87e-90	308.0	COG1680@1|root,COG1680@2|Bacteria,2GJJB@201174|Actinobacteria	201174|Actinobacteria	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS1_k127_5509552_1	102125.Xen7305DRAFT_00022750	9.632e-105	347.0	COG3677@1|root,COG3677@2|Bacteria,1GEA3@1117|Cyanobacteria	1117|Cyanobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5519154_7	1173026.Glo7428_1852	7.299e-46	177.0	COG2334@1|root,COG2334@2|Bacteria,1G3HF@1117|Cyanobacteria	1117|Cyanobacteria	S	homoserine kinase type II (Protein kinase fold)	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS1_k127_5519154_9	1173029.JH980292_gene2357	1.958e-17	88.0	2AFVV@1|root,33H4H@2|Bacteria,1GANU@1117|Cyanobacteria,1HGHN@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5519154_0	935948.KE386493_gene2380	1.707e-168	535.0	COG0407@1|root,COG0407@2|Bacteria,1V4YU@1239|Firmicutes,24FCZ@186801|Clostridia,42HY1@68295|Thermoanaerobacterales	186801|Clostridia	H	PFAM Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
CMS1_k127_5519154_4	880073.Calab_3431	4.821e-77	269.0	COG0407@1|root,COG0407@2|Bacteria,2NPXG@2323|unclassified Bacteria	2|Bacteria	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
CMS1_k127_5519154_6	545695.TREAZ_3613	1.13e-65	239.0	COG0407@1|root,COG0407@2|Bacteria	2|Bacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
CMS1_k127_5519154_3	697281.Mahau_2948	1.237e-101	343.0	COG0407@1|root,COG0407@2|Bacteria,1UY51@1239|Firmicutes,24DZF@186801|Clostridia,42FW9@68295|Thermoanaerobacterales	186801|Clostridia	H	PFAM Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
CMS1_k127_5519154_5	545695.TREAZ_3490	3.468e-68	244.0	COG5012@1|root,COG5012@2|Bacteria	2|Bacteria	T	cobalamin binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5519154_1	278957.ABEA03000166_gene4026	1.95e-118	391.0	COG0407@1|root,COG0407@2|Bacteria	278957.ABEA03000166_gene4026|-	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5519154_2	935948.KE386495_gene1239	4.011e-105	353.0	COG0407@1|root,COG0407@2|Bacteria,1UY51@1239|Firmicutes,24DZF@186801|Clostridia,42FW9@68295|Thermoanaerobacterales	186801|Clostridia	H	PFAM Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
CMS1_k127_5519154_8	1089553.Tph_c05860	2.239e-39	149.0	COG5012@1|root,COG5012@2|Bacteria,1V1P0@1239|Firmicutes,24G08@186801|Clostridia,42FJI@68295|Thermoanaerobacterales	186801|Clostridia	S	Methionine synthase B12-binding module cap domain protein	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2
CMS1_k127_5524522_7	765420.OSCT_2991	5.971e-33	142.0	COG2010@1|root,COG3258@1|root,COG2010@2|Bacteria,COG3258@2|Bacteria	2|Bacteria	C	Cytochrome c	qcrC	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005507,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006464,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016021,GO:0016491,GO:0016667,GO:0016669,GO:0016740,GO:0016782,GO:0016783,GO:0018192,GO:0018193,GO:0018198,GO:0018307,GO:0019417,GO:0019538,GO:0020037,GO:0022900,GO:0031224,GO:0031226,GO:0036211,GO:0040007,GO:0042597,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046906,GO:0046914,GO:0046982,GO:0046983,GO:0048037,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:0098822,GO:1901363,GO:1901564	1.8.2.2	ko:K00406,ko:K03889,ko:K17222,ko:K19713	ko00190,ko00920,ko01100,ko01120,ko02020,map00190,map00920,map01100,map01120,map02020	M00151,M00156,M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cytochrome_CBB3
CMS1_k127_5524522_5	765420.OSCT_2992	6.447e-37	145.0	COG0723@1|root,COG0723@2|Bacteria,2GB28@200795|Chloroflexi,377SJ@32061|Chloroflexia	32061|Chloroflexia	C	Rieske [2Fe-2S] domain	-	-	1.10.9.1	ko:K02636	ko00195,ko01100,map00195,map01100	M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Rieske
CMS1_k127_5524522_6	671143.DAMO_0768	2.197e-35	145.0	COG1290@1|root,COG1290@2|Bacteria,2NP8C@2323|unclassified Bacteria	2|Bacteria	C	Cytochrome b(N-terminal)/b6/petB	petB	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B_C,Cytochrome_B
CMS1_k127_5524522_1	1382306.JNIM01000001_gene1047	9.442e-89	298.0	COG1290@1|root,COG1290@2|Bacteria,2G8QQ@200795|Chloroflexi	200795|Chloroflexi	C	Cytochrome b(N-terminal)/b6/petB	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_B
CMS1_k127_5524522_3	1121033.AUCF01000010_gene4432	7.466e-53	205.0	COG2010@1|root,COG2010@2|Bacteria,1REKI@1224|Proteobacteria,2UA53@28211|Alphaproteobacteria,2JWXG@204441|Rhodospirillales	204441|Rhodospirillales	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CMS1_k127_5524522_0	671143.DAMO_0766	2.005e-185	599.0	COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,2NNUW@2323|unclassified Bacteria	2|Bacteria	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	pcmB	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6,1.97.1.9	ko:K03388,ko:K12527	ko00450,ko00680,ko01100,ko01120,ko01200,map00450,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R07229,R11928,R11931,R11943,R11944	RC00011,RC02420	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,FlpD,Pyr_redox_2,Pyr_redox_3
CMS1_k127_5524522_2	926569.ANT_19360	9.818e-66	232.0	COG0745@1|root,COG0745@2|Bacteria	926569.ANT_19360|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5524522_4	926569.ANT_19350	1.045e-44	180.0	COG0642@1|root,COG3283@1|root,COG2205@2|Bacteria,COG3283@2|Bacteria	2|Bacteria	EK	Transcriptional regulator of aromatic amino acids metabolism	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	ANTAR,GAF_2,GGDEF,HATPase_c,HD_5,HisKA,LytTR,PAS,PAS_3,PAS_4,PAS_9,Response_reg
CMS1_k127_5524522_8	935837.JAEK01000011_gene135	8.881e-07	55.0	COG4644@1|root,COG4644@2|Bacteria,1TRGX@1239|Firmicutes,4HAJF@91061|Bacilli,1ZB7A@1386|Bacillus	91061|Bacilli	L	Transposase and inactivated derivatives, TnpA family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_Tn3,DUF4158
CMS1_k127_5524916_3	941824.TCEL_00878	3.873e-37	143.0	COG2998@1|root,COG2998@2|Bacteria,1TQA9@1239|Firmicutes,249EZ@186801|Clostridia,36ERE@31979|Clostridiaceae	186801|Clostridia	H	PBP superfamily domain	tupA	-	-	ko:K05772	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	PBP_like_2
CMS1_k127_5524916_1	1122201.AUAZ01000003_gene2080	3.205e-58	212.0	COG0730@1|root,COG0730@2|Bacteria,1MVY3@1224|Proteobacteria,1S21M@1236|Gammaproteobacteria,467A8@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
CMS1_k127_5524916_4	1128421.JAGA01000001_gene2168	6.552e-21	96.0	COG2005@1|root,COG2005@2|Bacteria,2NRCV@2323|unclassified Bacteria	2|Bacteria	S	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	ko:K02019,ko:K05772	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000,ko03000	3.A.1.6.2,3.A.1.6.4	-	-	HTH_1,PBP_like_2
CMS1_k127_5524916_2	1254432.SCE1572_01090	7.908e-43	163.0	COG1403@1|root,COG1403@2|Bacteria,1NN2J@1224|Proteobacteria	1224|Proteobacteria	V	SMART HNH nuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
CMS1_k127_5524916_6	1444309.JAQG01000036_gene4840	3.223e-06	59.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	DUF5050
CMS1_k127_5524916_0	926550.CLDAP_00650	2.589e-150	482.0	COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,2G5NF@200795|Chloroflexi	200795|Chloroflexi	C	COGs COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs	xdh	-	-	ko:K12528	ko00450,map00450	-	R07229	RC02420	ko00000,ko00001	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
CMS1_k127_5532032_2	292459.STH292	6.284e-38	155.0	COG2971@1|root,COG2971@2|Bacteria,1V0VG@1239|Firmicutes,24BFK@186801|Clostridia	186801|Clostridia	G	BadF BadG BcrA BcrD	-	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006040,GO:0006044,GO:0006082,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0045127,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901071,GO:1901135,GO:1901265,GO:1901363	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
CMS1_k127_5532032_1	935839.JAGJ01000011_gene475	1.553e-236	753.0	COG1109@1|root,COG1207@1|root,COG1109@2|Bacteria,COG1207@2|Bacteria,2IB2T@201174|Actinobacteria,4F59Y@85017|Promicromonosporaceae	201174|Actinobacteria	GM	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3,PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
CMS1_k127_5532032_0	926550.CLDAP_32080	1.927e-244	768.0	COG0747@1|root,COG0747@2|Bacteria,2G7XC@200795|Chloroflexi	200795|Chloroflexi	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_5538597_6	999611.KI421504_gene1528	2.702e-06	50.0	COG3119@1|root,COG3119@2|Bacteria,1MV0B@1224|Proteobacteria,2TRI6@28211|Alphaproteobacteria,28147@191028|Leisingera	28211|Alphaproteobacteria	P	Choline sulfatase enzyme C terminal	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
CMS1_k127_5538597_5	497964.CfE428DRAFT_2331	1.049e-50	201.0	COG0627@1|root,COG0627@2|Bacteria	2|Bacteria	J	Serine hydrolase involved in the detoxification of formaldehyde	-	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	Esterase
CMS1_k127_5538597_3	530564.Psta_1537	1.263e-75	275.0	COG0657@1|root,COG0657@2|Bacteria,2IXCK@203682|Planctomycetes	203682|Planctomycetes	I	COG0657 Esterase lipase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,EF-hand_5,Peptidase_S9
CMS1_k127_5538597_1	1121904.ARBP01000040_gene530	1.818e-105	360.0	COG3119@1|root,COG3119@2|Bacteria,4NGX1@976|Bacteroidetes,47K2H@768503|Cytophagia	976|Bacteroidetes	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS1_k127_5538597_0	378806.STAUR_5260	7.23e-123	405.0	COG2706@1|root,COG2706@2|Bacteria,1MUKZ@1224|Proteobacteria,4394D@68525|delta/epsilon subdivisions,2X4AE@28221|Deltaproteobacteria,2YYM5@29|Myxococcales	28221|Deltaproteobacteria	G	Lactonase, 7-bladed beta-propeller	-	-	3.1.1.31	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Lactonase
CMS1_k127_5538597_2	1379698.RBG1_1C00001G0168	6.6e-101	334.0	COG1209@1|root,COG1209@2|Bacteria,2NNTJ@2323|unclassified Bacteria	2|Bacteria	M	Nucleotidyl transferase	spsI	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
CMS1_k127_5538597_4	1033743.CAES01000046_gene267	1.426e-56	207.0	COG0520@1|root,COG0520@2|Bacteria,1UNKQ@1239|Firmicutes,4HTGN@91061|Bacilli	91061|Bacilli	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
CMS1_k127_5541419_5	926550.CLDAP_11410	6.811e-26	115.0	COG1559@1|root,COG1559@2|Bacteria,2G6G8@200795|Chloroflexi	200795|Chloroflexi	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
CMS1_k127_5541419_0	502025.Hoch_4063	1.398e-160	514.0	COG4948@1|root,COG4948@2|Bacteria,1MURK@1224|Proteobacteria	1224|Proteobacteria	M	Belongs to the mandelate racemase muconate lactonizing enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
CMS1_k127_5541419_2	1051632.TPY_1196	2.172e-75	263.0	COG1809@1|root,COG1809@2|Bacteria,1V20V@1239|Firmicutes,24EBV@186801|Clostridia	186801|Clostridia	S	PFAM (2R)-phospho-3-sulfolactate synthase ComA	comA	-	4.4.1.19	ko:K08097	ko00680,ko01120,map00680,map01120	M00358	R07476	RC01799	ko00000,ko00001,ko00002,ko01000	-	-	-	ComA
CMS1_k127_5541419_3	589924.Ferp_1757	1.322e-44	166.0	COG0599@1|root,arCOG02148@2157|Archaea	2157|Archaea	S	PFAM Carboxymuconolactone decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS1_k127_5541419_1	292459.STH3153	4.933e-123	411.0	COG3278@1|root,COG3278@2|Bacteria,1V0VX@1239|Firmicutes	1239|Firmicutes	P	Cytochrome C and Quinol oxidase polypeptide I	-	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
CMS1_k127_5541419_4	292459.STH3152	4.927e-30	125.0	COG2010@1|root,COG2993@1|root,COG2010@2|Bacteria,COG2993@2|Bacteria,1V9A2@1239|Firmicutes	1239|Firmicutes	C	Cytochrome C oxidase, mono-heme subunit/FixO	-	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixO
CMS1_k127_5544695_0	1128421.JAGA01000002_gene1751	2.938e-149	479.0	COG0626@1|root,COG0626@2|Bacteria,2NNNS@2323|unclassified Bacteria	2|Bacteria	E	Cys/Met metabolism PLP-dependent enzyme	metB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8	ko:K01739,ko:K01758,ko:K01760,ko:K01761	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00654,R00782,R00999,R01001,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00196,RC00348,RC00382,RC00420,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iNJ661.Rv1079	Cys_Met_Meta_PP
CMS1_k127_5544695_1	439235.Dalk_1526	3.03e-42	179.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,42NXT@68525|delta/epsilon subdivisions,2WIZ3@28221|Deltaproteobacteria,2MKIU@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc,Pkinase,TPR_12
CMS1_k127_5549440_21	926550.CLDAP_04460	1.968e-17	84.0	COG1807@1|root,COG1807@2|Bacteria,2G8YZ@200795|Chloroflexi	200795|Chloroflexi	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5549440_4	926550.CLDAP_04470	4.443e-97	340.0	COG1807@1|root,COG1807@2|Bacteria,2G9RZ@200795|Chloroflexi	200795|Chloroflexi	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5549440_16	926550.CLDAP_04480	8.966e-40	161.0	COG0392@1|root,COG0392@2|Bacteria,2G6NX@200795|Chloroflexi	200795|Chloroflexi	S	PFAM conserved	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
CMS1_k127_5549440_12	316274.Haur_1551	2.935e-55	204.0	COG1496@1|root,COG1496@2|Bacteria,2G6N5@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the multicopper oxidase YfiH RL5 family	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
CMS1_k127_5549440_11	357808.RoseRS_3251	4.285e-63	224.0	COG0325@1|root,COG0325@2|Bacteria,2G6F1@200795|Chloroflexi,375I2@32061|Chloroflexia	32061|Chloroflexia	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
CMS1_k127_5549440_6	357808.RoseRS_0390	3.538e-88	299.0	COG0345@1|root,COG0345@2|Bacteria,2G5QD@200795|Chloroflexi,375AU@32061|Chloroflexia	32061|Chloroflexia	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
CMS1_k127_5549440_23	1123371.ATXH01000013_gene1554	2.94e-07	55.0	COG0762@1|root,COG0762@2|Bacteria,2GHYF@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
CMS1_k127_5549440_24	485916.Dtox_1088	9.652e-06	51.0	COG1872@1|root,COG1872@2|Bacteria,1VFSH@1239|Firmicutes,24T87@186801|Clostridia,262RJ@186807|Peptococcaceae	186801|Clostridia	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
CMS1_k127_5549440_18	351160.RCIX443	2.232e-28	118.0	COG0745@1|root,arCOG02595@2157|Archaea,2XZSB@28890|Euryarchaeota,2NAXV@224756|Methanomicrobia	224756|Methanomicrobia	T	cheY-homologous receiver domain	-	-	-	ko:K07668	ko02020,map02020	M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
CMS1_k127_5549440_14	926569.ANT_16430	1.324e-41	156.0	COG0745@1|root,COG0745@2|Bacteria	926569.ANT_16430|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5549440_20	999411.HMPREF1092_00949	1.056e-24	108.0	COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,25AZ2@186801|Clostridia,36ESG@31979|Clostridiaceae	186801|Clostridia	T	PFAM response regulator receiver	phoP	-	-	ko:K02483,ko:K07658,ko:K07668	ko02020,map02020	M00434,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_5549440_22	1111131.HMPREF1255_0606	2.249e-10	63.0	COG0230@1|root,COG0230@2|Bacteria,2GQFY@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
CMS1_k127_5549440_19	926550.CLDAP_04250	5.844e-28	116.0	COG0594@1|root,COG0594@2|Bacteria,2G76W@200795|Chloroflexi	200795|Chloroflexi	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
CMS1_k127_5549440_17	485913.Krac_8806	3.805e-30	119.0	COG0759@1|root,COG0759@2|Bacteria,2G76Q@200795|Chloroflexi	200795|Chloroflexi	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
CMS1_k127_5549440_10	3218.PP1S198_153V6.2	2.867e-65	233.0	COG0706@1|root,KOG1239@2759|Eukaryota,37IIV@33090|Viridiplantae,3GB9B@35493|Streptophyta	35493|Streptophyta	OU	Inner membrane protein PPF-1	-	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006605,GO:0006612,GO:0006810,GO:0006886,GO:0006996,GO:0008104,GO:0008150,GO:0009507,GO:0009534,GO:0009535,GO:0009536,GO:0009579,GO:0009657,GO:0009668,GO:0009987,GO:0010027,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0017038,GO:0019904,GO:0022607,GO:0031976,GO:0031984,GO:0032991,GO:0033036,GO:0033365,GO:0034357,GO:0034613,GO:0042651,GO:0042886,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0044743,GO:0045036,GO:0045038,GO:0045184,GO:0046907,GO:0050789,GO:0050793,GO:0050794,GO:0051179,GO:0051234,GO:0051259,GO:0051291,GO:0051641,GO:0051649,GO:0055035,GO:0055085,GO:0061024,GO:0065002,GO:0065003,GO:0065007,GO:0070206,GO:0070208,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0072594,GO:0072596,GO:0072598,GO:0072657,GO:0090150,GO:0090342	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
CMS1_k127_5549440_15	926569.ANT_22890	7.012e-41	162.0	COG1847@1|root,COG1847@2|Bacteria,2G6XH@200795|Chloroflexi	200795|Chloroflexi	S	PFAM single-stranded nucleic acid binding R3H domain protein	-	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
CMS1_k127_5549440_7	926550.CLDAP_04300	4.47e-87	296.0	COG1192@1|root,COG1192@2|Bacteria,2G62U@200795|Chloroflexi	200795|Chloroflexi	D	PFAM Cobyrinic acid a,c-diamide synthase	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
CMS1_k127_5549440_9	309801.trd_1054	1.651e-77	268.0	COG1475@1|root,COG1475@2|Bacteria,2G6EK@200795|Chloroflexi,27XFW@189775|Thermomicrobia	189775|Thermomicrobia	K	ParB-like nuclease domain	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
CMS1_k127_5549440_8	926569.ANT_12940	8.489e-82	286.0	COG0793@1|root,COG0793@2|Bacteria,2G6HR@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
CMS1_k127_5549440_5	926550.CLDAP_30680	4.729e-93	320.0	COG0793@1|root,COG0793@2|Bacteria,2G6HR@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
CMS1_k127_5549440_13	28042.GU90_16420	3.062e-52	188.0	COG0691@1|root,COG0691@2|Bacteria,2GJX1@201174|Actinobacteria,4E2R0@85010|Pseudonocardiales	201174|Actinobacteria	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
CMS1_k127_5549440_2	344747.PM8797T_00679	1.638e-120	400.0	COG0019@1|root,COG0019@2|Bacteria,2IX3R@203682|Planctomycetes	203682|Planctomycetes	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
CMS1_k127_5549440_0	926550.CLDAP_09870	8.221e-203	647.0	COG0366@1|root,COG0366@2|Bacteria	2|Bacteria	G	hydrolase activity, hydrolyzing O-glycosyl compounds	ycjM	-	2.4.1.7	ko:K00690	ko00500,map00500	-	R00803	RC00028	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459,Malt_amylase_C
CMS1_k127_5549440_3	1128421.JAGA01000002_gene531	4.87e-105	347.0	COG2013@1|root,COG2013@2|Bacteria	2|Bacteria	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
CMS1_k127_5549440_1	1047013.AQSP01000097_gene1950	1.392e-201	634.0	COG0205@1|root,COG0205@2|Bacteria,2NNY2@2323|unclassified Bacteria	2|Bacteria	G	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfk-3	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
CMS1_k127_557518_4	471852.Tcur_2549	1.378e-12	72.0	COG0457@1|root,COG1672@1|root,COG0457@2|Bacteria,COG1672@2|Bacteria,2IEQR@201174|Actinobacteria,4EIC4@85012|Streptosporangiales	201174|Actinobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
CMS1_k127_557518_2	765420.OSCT_3186	1.286e-86	312.0	COG4995@1|root,COG4995@2|Bacteria,2G8YF@200795|Chloroflexi,377C0@32061|Chloroflexia	32061|Chloroflexia	P	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,SIR2_2
CMS1_k127_557518_1	309801.trd_1433	3.488e-99	339.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_557518_0	1267535.KB906767_gene4392	1.168e-210	664.0	COG0161@1|root,COG0161@2|Bacteria,3Y99B@57723|Acidobacteria,2JP5I@204432|Acidobacteriia	204432|Acidobacteriia	H	Aminotransferase class-III	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
CMS1_k127_557518_3	1306990.BARG01000031_gene3531	6.63e-26	120.0	COG0624@1|root,COG0624@2|Bacteria,2I8IJ@201174|Actinobacteria	201174|Actinobacteria	E	Acetylornithine deacetylase	argE	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
CMS1_k127_5587943_7	1297742.A176_06397	5.006e-33	130.0	COG1352@1|root,COG1352@2|Bacteria,1RDBE@1224|Proteobacteria,42RSH@68525|delta/epsilon subdivisions,2WNHY@28221|Deltaproteobacteria,2YXP4@29|Myxococcales	28221|Deltaproteobacteria	NT	Methyltransferase, chemotaxis proteins	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
CMS1_k127_5587943_4	926550.CLDAP_21560	8.031e-60	229.0	COG5305@1|root,COG5305@2|Bacteria,2G7AA@200795|Chloroflexi	200795|Chloroflexi	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS1_k127_5587943_8	1110502.TMO_1613	0.0002926	46.0	COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,2TS4D@28211|Alphaproteobacteria,2JPKU@204441|Rhodospirillales	204441|Rhodospirillales	S	Penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
CMS1_k127_5587943_0	926560.KE387023_gene1159	3.507e-114	382.0	COG0513@1|root,COG0513@2|Bacteria,1WKZ3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	helicase superfamily c-terminal domain	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
CMS1_k127_5587943_1	883078.HMPREF9695_00945	1.372e-70	255.0	COG2271@1|root,COG2271@2|Bacteria,1QTW2@1224|Proteobacteria,2U07Z@28211|Alphaproteobacteria,3JR8H@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	Major Facilitator Superfamily	MA20_02120	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_5587943_2	219305.MCAG_01140	2.099e-68	241.0	COG0410@1|root,COG0410@2|Bacteria,2GKSQ@201174|Actinobacteria,4D9QU@85008|Micromonosporales	201174|Actinobacteria	E	COG0410 ABC-type branched-chain amino acid transport systems, ATPase component	livF	-	-	ko:K01995,ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
CMS1_k127_5587943_3	28072.Nos7524_4268	7.021e-66	233.0	COG0411@1|root,COG0411@2|Bacteria,1G07Z@1117|Cyanobacteria,1HIDV@1161|Nostocales	1117|Cyanobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	natA	-	-	ko:K01995,ko:K11957	ko02010,ko02024,map02010,map02024	M00237,M00322	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4,3.A.1.4.2,3.A.1.4.6	-	-	ABC_tran,BCA_ABC_TP_C
CMS1_k127_5587943_5	1121939.L861_19330	2.751e-53	202.0	COG4177@1|root,COG4177@2|Bacteria,1MU52@1224|Proteobacteria,1SZ2G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
CMS1_k127_5587943_6	666684.AfiDRAFT_1899	1.221e-52	196.0	COG0559@1|root,COG0559@2|Bacteria,1P3FU@1224|Proteobacteria,2TT3V@28211|Alphaproteobacteria,3JUY0@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
CMS1_k127_5589877_2	246197.MXAN_7206	2.236e-29	130.0	COG2204@1|root,COG3292@1|root,COG4191@1|root,COG2204@2|Bacteria,COG3292@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42Q3F@68525|delta/epsilon subdivisions,2WM2F@28221|Deltaproteobacteria,2YUEQ@29|Myxococcales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Reg_prop,Response_reg,Y_Y_Y
CMS1_k127_5589877_0	1128421.JAGA01000002_gene1889	1.2e-137	443.0	COG2084@1|root,COG2084@2|Bacteria	2|Bacteria	I	phosphogluconate dehydrogenase (decarboxylating) activity	glxR	-	1.1.1.31,1.1.1.60	ko:K00020,ko:K00042	ko00280,ko00630,ko01100,map00280,map00630,map01100	-	R01745,R01747,R05066	RC00099	ko00000,ko00001,ko01000	-	-	iJN678.mmsB	NAD_binding_11,NAD_binding_2
CMS1_k127_5589877_1	485913.Krac_2547	1.7e-129	423.0	COG0492@1|root,COG0492@2|Bacteria,2G5Z5@200795|Chloroflexi	2|Bacteria	C	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Glutaredoxin,Pyr_redox_2
CMS1_k127_5594596_0	485913.Krac_3174	8.467e-76	258.0	COG0617@1|root,COG0617@2|Bacteria,2G8X7@200795|Chloroflexi	200795|Chloroflexi	J	Aminoglycoside-2''-adenylyltransferase	-	-	-	ko:K19545	-	-	-	-	ko00000,ko01504	-	-	-	NTP_transf_5
CMS1_k127_5594596_4	675635.Psed_4970	1.036e-26	118.0	COG0500@1|root,COG2226@2|Bacteria,2GNJS@201174|Actinobacteria,4E1EP@85010|Pseudonocardiales	201174|Actinobacteria	Q	Hypothetical methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS1_k127_5594596_3	1487953.JMKF01000028_gene1227	8.474e-29	128.0	COG0454@1|root,COG0456@2|Bacteria,1G407@1117|Cyanobacteria,1H9GX@1150|Oscillatoriales	1117|Cyanobacteria	K	PFAM Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS1_k127_5594596_2	558169.AGAV01000022_gene246	1.771e-43	168.0	COG0500@1|root,COG2226@2|Bacteria,1UZN6@1239|Firmicutes,4HB38@91061|Bacilli	91061|Bacilli	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS1_k127_5594596_1	1227457.C451_15035	2.042e-47	179.0	COG0863@1|root,arCOG00115@2157|Archaea,2XXQ9@28890|Euryarchaeota,23VYI@183963|Halobacteria	183963|Halobacteria	L	COG0863 DNA modification methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase
CMS1_k127_5594596_5	316274.Haur_4733	9.31e-05	46.0	COG0494@1|root,COG0494@2|Bacteria	2|Bacteria	L	nUDIX hydrolase	-	-	3.6.1.17	ko:K01518,ko:K08296	ko00230,ko00240,map00230,map00240	-	R00184,R00969,R01232,R02805	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
CMS1_k127_5595722_3	1123242.JH636434_gene5497	1.264e-82	279.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2IXK8@203682|Planctomycetes	203682|Planctomycetes	E	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
CMS1_k127_5595722_2	1116232.AHBF01000139_gene1782	6.348e-84	293.0	COG0399@1|root,COG0399@2|Bacteria,2GKD7@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the DegT DnrJ EryC1 family	stsA	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
CMS1_k127_5595722_6	649747.HMPREF0083_03812	1.689e-66	244.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,1TRC3@1239|Firmicutes,4HADQ@91061|Bacilli,26R5S@186822|Paenibacillaceae	91061|Bacilli	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	ctaC	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C,Cytochrome_CBB3
CMS1_k127_5595722_1	469383.Cwoe_1902	2.779e-158	520.0	COG0843@1|root,COG0843@2|Bacteria,2GJHX@201174|Actinobacteria	201174|Actinobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
CMS1_k127_5595722_5	926550.CLDAP_10590	1.39e-75	258.0	COG1845@1|root,COG1845@2|Bacteria,2G74U@200795|Chloroflexi	200795|Chloroflexi	C	PFAM cytochrome c oxidase, subunit III	-	-	1.9.3.1	ko:K02276,ko:K02299	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX3
CMS1_k127_5595722_4	926550.CLDAP_10580	1.45e-76	266.0	COG3336@1|root,COG3336@2|Bacteria,2G725@200795|Chloroflexi	200795|Chloroflexi	C	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)	-	-	-	-	-	-	-	-	-	-	-	-	Caa3_CtaG
CMS1_k127_5595722_7	926550.CLDAP_10560	3.233e-45	175.0	COG3346@1|root,COG3346@2|Bacteria,2G8X9@200795|Chloroflexi	200795|Chloroflexi	S	SURF1 family	-	-	-	ko:K14998	-	-	-	-	ko00000,ko03029	3.D.4.8	-	-	SURF1
CMS1_k127_5595722_0	1313421.JHBV01000020_gene5217	1.197e-168	542.0	COG0076@1|root,COG0076@2|Bacteria,4NFUP@976|Bacteroidetes	976|Bacteroidetes	E	COG0076 Glutamate decarboxylase and related PLP-dependent	-	-	-	-	-	-	-	-	-	-	-	-	Pyridoxal_deC
CMS1_k127_5595722_11	926550.CLDAP_10570	1.16e-12	76.0	COG2373@1|root,COG2373@2|Bacteria	2|Bacteria	U	Large extracellular alpha-helical protein	-	-	-	ko:K13735	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	CHU_C,DUF11,SdrD_B
CMS1_k127_5595722_8	933801.Ahos_1093	3.631e-43	169.0	COG0109@1|root,arCOG00479@2157|Archaea,2XQH8@28889|Crenarchaeota	28889|Crenarchaeota	H	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
CMS1_k127_5595722_10	323259.Mhun_0970	2.427e-27	128.0	COG3291@1|root,arCOG02516@1|root,arCOG02508@2157|Archaea,arCOG02510@2157|Archaea,arCOG02516@2157|Archaea,2XUY6@28890|Euryarchaeota,2NAFS@224756|Methanomicrobia	224756|Methanomicrobia	O	PFAM PKD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	PKD
CMS1_k127_5595722_9	68170.KL590499_gene4927	3.355e-29	134.0	COG2931@1|root,COG2931@2|Bacteria,2GR03@201174|Actinobacteria,4E8ZQ@85010|Pseudonocardiales	201174|Actinobacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	An_peroxidase,HemolysinCabind,Peptidase_M91,fn3
CMS1_k127_5599565_0	756067.MicvaDRAFT_2506	3.099e-271	874.0	COG1020@1|root,COG1020@2|Bacteria,1G0XE@1117|Cyanobacteria,1H9T8@1150|Oscillatoriales	1117|Cyanobacteria	Q	Amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase
CMS1_k127_5599565_1	880073.Calab_0213	5.734e-98	329.0	COG0530@1|root,COG0530@2|Bacteria,2NPPD@2323|unclassified Bacteria	2|Bacteria	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
CMS1_k127_5629143_0	1128421.JAGA01000002_gene995	3.877e-156	507.0	COG1075@1|root,COG1075@2|Bacteria	2|Bacteria	KLT	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,CHAT,LCAT
CMS1_k127_5629143_1	880073.Calab_0031	1.871e-145	468.0	COG2017@1|root,COG2017@2|Bacteria,2NQA5@2323|unclassified Bacteria	2|Bacteria	G	Converts alpha-aldose to the beta-anomer	mro	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
CMS1_k127_5630423_3	926550.CLDAP_23100	7.66e-113	373.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
CMS1_k127_5630423_2	926550.CLDAP_23090	4.492e-114	376.0	COG1175@1|root,COG1175@2|Bacteria	2|Bacteria	P	transmembrane transport	-	-	-	ko:K02025,ko:K05814,ko:K10118,ko:K10237,ko:K10241,ko:K15771,ko:K17235,ko:K17242,ko:K17316	ko02010,map02010	M00196,M00198,M00204,M00206,M00207,M00491,M00600,M00602,M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.17,3.A.1.1.2,3.A.1.1.23,3.A.1.1.24,3.A.1.1.28,3.A.1.1.3,3.A.1.1.30,3.A.1.1.34,3.A.1.1.39	-	-	BPD_transp_1
CMS1_k127_5630423_1	926550.CLDAP_23080	4.192e-115	377.0	COG0395@1|root,COG0395@2|Bacteria	2|Bacteria	P	glycerophosphodiester transmembrane transport	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_5630423_6	649638.Trad_0655	1.141e-60	224.0	COG2271@1|root,COG2271@2|Bacteria	2|Bacteria	G	transmembrane transporter activity	-	-	-	ko:K05820	-	-	-	-	ko00000,ko02000	2.A.1.27	-	-	MFS_1
CMS1_k127_5630423_8	1122228.AQXR01000006_gene1178	8.002e-30	134.0	COG1653@1|root,COG1653@2|Bacteria,2HZBJ@201174|Actinobacteria,4CZJJ@85004|Bifidobacteriales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
CMS1_k127_5630423_4	525904.Tter_2572	2.335e-71	252.0	COG0395@1|root,COG0395@2|Bacteria,2NPFW@2323|unclassified Bacteria	2|Bacteria	U	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_5630423_5	1449357.JQLK01000001_gene398	4.229e-66	237.0	COG1175@1|root,COG1175@2|Bacteria,1WJ21@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_5630423_7	926550.CLDAP_32730	3.624e-33	145.0	COG5598@1|root,COG5598@2|Bacteria	2|Bacteria	H	trimethylamine methyltransferase	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
CMS1_k127_5630423_0	28444.JODQ01000004_gene6448	5.215e-152	494.0	COG1486@1|root,COG1486@2|Bacteria,2GK80@201174|Actinobacteria	201174|Actinobacteria	G	family 4	malH	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_4,Glyco_hydro_4C
CMS1_k127_5631669_1	28072.Nos7524_0911	1.243e-114	385.0	COG3385@1|root,COG3385@2|Bacteria,1G3D9@1117|Cyanobacteria	1117|Cyanobacteria	L	Transposase DNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,Dimer_Tnp_Tn5,Tnp_DNA_bind
CMS1_k127_5631669_2	926550.CLDAP_21770	1.268e-88	301.0	COG0077@1|root,COG0077@2|Bacteria,2G6AP@200795|Chloroflexi	200795|Chloroflexi	E	amino acid-binding ACT domain protein	pheA	-	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	PDT
CMS1_k127_5631669_0	926569.ANT_01870	5.293e-121	397.0	COG2876@1|root,COG2876@2|Bacteria,2G643@200795|Chloroflexi	200795|Chloroflexi	E	PFAM DAHP synthetase I KDSA	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
CMS1_k127_5631669_3	316067.Geob_3586	1.091e-80	272.0	COG0225@1|root,COG0225@2|Bacteria,1MVUS@1224|Proteobacteria,43BC4@68525|delta/epsilon subdivisions,2WPKB@28221|Deltaproteobacteria,43UN1@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Peptide methionine sulfoxide reductase	-	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
CMS1_k127_5631669_4	1121422.AUMW01000006_gene794	2.293e-50	202.0	COG1624@1|root,COG1624@2|Bacteria,1TPRW@1239|Firmicutes,249K8@186801|Clostridia,2611Q@186807|Peptococcaceae	186801|Clostridia	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
CMS1_k127_563426_1	502025.Hoch_6445	1.468e-140	454.0	COG3488@1|root,COG3488@2|Bacteria	2|Bacteria	C	Di-haem oxidoreductase, putative peroxidase	-	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	DHOR
CMS1_k127_563426_0	383372.Rcas_2454	5.355e-213	681.0	COG0747@1|root,COG0747@2|Bacteria,2G84E@200795|Chloroflexi	200795|Chloroflexi	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_563426_2	661478.OP10G_2681	6.323e-26	119.0	COG5285@1|root,COG5285@2|Bacteria	2|Bacteria	Q	dioxygenase activity	-	-	1.14.11.18	ko:K00477	ko04146,map04146	-	-	-	ko00000,ko00001,ko01000	-	-	-	PhyH
CMS1_k127_5637203_1	926550.CLDAP_11490	1.2e-94	312.0	COG1053@1|root,COG1053@2|Bacteria	2|Bacteria	C	succinate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
CMS1_k127_5637203_2	479434.Sthe_3401	3.283e-93	312.0	COG0664@1|root,COG0664@2|Bacteria,2G6WI@200795|Chloroflexi	200795|Chloroflexi	K	PFAM Cyclic nucleotide-binding	-	-	-	ko:K10914,ko:K21564	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CMS1_k127_5637203_3	479434.Sthe_3400	1.596e-26	109.0	COG2608@1|root,COG2608@2|Bacteria	2|Bacteria	P	mercury ion transmembrane transporter activity	-	-	-	ko:K07213	ko04978,map04978	-	-	-	ko00000,ko00001	-	-	-	HMA
CMS1_k127_5637203_0	479434.Sthe_3399	2.574e-260	818.0	COG2217@1|root,COG2217@2|Bacteria,2G5QF@200795|Chloroflexi	2|Bacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copA	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,Hydrolase
CMS1_k127_5637203_5	1200792.AKYF01000010_gene2809	1.566e-09	64.0	2ANJW@1|root,31DIZ@2|Bacteria,1W62E@1239|Firmicutes,4I0FA@91061|Bacilli	91061|Bacilli	S	Protein of unknown function (DUF3054)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3054
CMS1_k127_5637203_6	568816.Acin_1096	1.923e-06	54.0	COG0662@1|root,COG0662@2|Bacteria,1V70W@1239|Firmicutes,4H5H8@909932|Negativicutes	909932|Negativicutes	G	Cupin domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS1_k127_5637203_4	926560.KE387025_gene3959	5.376e-12	66.0	COG1506@1|root,COG1506@2|Bacteria,1WNJA@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	X-Pro dipeptidyl-peptidase (S15 family)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
CMS1_k127_5639740_3	1121918.ARWE01000001_gene1726	4.052e-34	134.0	COG3093@1|root,COG3093@2|Bacteria,1N76J@1224|Proteobacteria,42WQS@68525|delta/epsilon subdivisions,2WRPT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Helix-turn-helix XRE-family like proteins	higA	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
CMS1_k127_5639740_2	525904.Tter_2344	1.898e-56	201.0	COG1472@1|root,COG1472@2|Bacteria,2NQT7@2323|unclassified Bacteria	2|Bacteria	G	Glycosyl hydrolase family 3 C-terminal domain	bgxA	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Glyco_hydro_3,Glyco_hydro_3_C
CMS1_k127_5639740_1	485913.Krac_4790	4.651e-87	295.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS1_k127_5639740_0	497964.CfE428DRAFT_1242	2.11e-161	518.0	COG0823@1|root,COG0823@2|Bacteria,46SJJ@74201|Verrucomicrobia	74201|Verrucomicrobia	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5639740_4	1305737.JAFX01000001_gene3410	8.479e-14	76.0	COG1082@1|root,COG1082@2|Bacteria,4NI4H@976|Bacteroidetes,47MMY@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS1_k127_5639740_5	575540.Isop_0819	5.528e-12	68.0	COG1082@1|root,COG1082@2|Bacteria,2IZ3D@203682|Planctomycetes	203682|Planctomycetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS1_k127_5640174_1	246194.CHY_0668	1.877e-74	267.0	COG0438@1|root,COG0438@2|Bacteria,1V2NV@1239|Firmicutes,25ERN@186801|Clostridia,42HMK@68295|Thermoanaerobacterales	186801|Clostridia	M	Glycosyl transferase 4-like domain	-	-	2.4.1.348	ko:K06338,ko:K12995	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glyco_transf_4,Glycos_transf_1
CMS1_k127_5640174_0	1128421.JAGA01000003_gene3086	7.176e-270	838.0	COG0443@1|root,COG0443@2|Bacteria,2NNU1@2323|unclassified Bacteria	2|Bacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
CMS1_k127_5640174_2	1121447.JONL01000006_gene149	1.019e-08	57.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2WIWS@28221|Deltaproteobacteria,2M9A5@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
CMS1_k127_5649749_1	926569.ANT_08520	4.404e-17	83.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,2G5ZX@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
CMS1_k127_5649749_0	326427.Cagg_1771	1.344e-197	668.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2G699@200795|Chloroflexi,3764S@32061|Chloroflexia	32061|Chloroflexia	T	PFAM adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Guanylate_cyc,TPR_12,TPR_2
CMS1_k127_5649749_2	1157490.EL26_05245	2.794e-06	61.0	COG1404@1|root,COG1572@1|root,COG3227@1|root,COG1404@2|Bacteria,COG1572@2|Bacteria,COG3227@2|Bacteria,1TP08@1239|Firmicutes,4H9S6@91061|Bacilli	91061|Bacilli	E	COG3227 Zinc metalloprotease (elastase)	mpl	GO:0005575,GO:0005576	3.4.24.28,3.4.24.29	ko:K01400,ko:K01401,ko:K19351	ko01503,ko05150,map01503,map05150	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	FTP,PepSY,Peptidase_M4,Peptidase_M4_C
CMS1_k127_5658027_1	1499967.BAYZ01000103_gene3780	1.338e-25	124.0	COG0457@1|root,COG0457@2|Bacteria	1499967.BAYZ01000103_gene3780|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5658027_3	1009370.ALO_19097	7.625e-16	92.0	2DBE5@1|root,2Z8QQ@2|Bacteria,1TPFD@1239|Firmicutes,4H21Z@909932|Negativicutes	909932|Negativicutes	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5658027_4	1198232.CYCME_1435	2.457e-13	83.0	COG2244@1|root,COG2244@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
CMS1_k127_5658027_0	311424.DhcVS_1338	4.44e-46	185.0	COG1032@1|root,COG1032@2|Bacteria,2G6ZI@200795|Chloroflexi,34CU8@301297|Dehalococcoidia	301297|Dehalococcoidia	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
CMS1_k127_5658027_2	1499967.BAYZ01000030_gene1171	4.394e-17	92.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,Methyltransf_11,Methyltransf_23
CMS1_k127_5659757_0	927677.ALVU02000001_gene4596	5.304e-248	810.0	COG1858@1|root,COG3391@1|root,COG1858@2|Bacteria,COG3391@2|Bacteria,1GAED@1117|Cyanobacteria	1117|Cyanobacteria	C	Lactonase, 7-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
CMS1_k127_5659757_4	47716.JOFH01000009_gene304	8.08e-13	74.0	COG2197@1|root,COG2197@2|Bacteria,2GN80@201174|Actinobacteria	201174|Actinobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS1_k127_5659757_3	316274.Haur_4485	9.281e-72	248.0	COG2197@1|root,COG2197@2|Bacteria,2G6T1@200795|Chloroflexi,376HK@32061|Chloroflexia	200795|Chloroflexi	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS1_k127_5659757_2	316274.Haur_4486	1.975e-114	391.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G8GW@200795|Chloroflexi,3776B@32061|Chloroflexia	200795|Chloroflexi	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
CMS1_k127_5659757_1	1173024.KI912151_gene2085	1.296e-141	463.0	COG2319@1|root,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1JKKM@1189|Stigonemataceae	1117|Cyanobacteria	S	NB-ARC domain	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC,WD40
CMS1_k127_5672736_13	911045.PSE_3895	1.437e-12	67.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,2TQP8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
CMS1_k127_5672736_15	266809.PM03_16415	0.0007044	46.0	COG0690@1|root,COG0690@2|Bacteria,1N75P@1224|Proteobacteria,2UF51@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
CMS1_k127_5672736_5	383372.Rcas_4321	6.485e-78	265.0	COG0250@1|root,COG0250@2|Bacteria,2G6A3@200795|Chloroflexi,37569@32061|Chloroflexia	32061|Chloroflexia	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
CMS1_k127_5672736_7	1336234.JAGN01000058_gene657	5.895e-59	207.0	COG0080@1|root,COG0080@2|Bacteria,1V1BS@1239|Firmicutes,4HFQ0@91061|Bacilli,27G6R@186828|Carnobacteriaceae	91061|Bacilli	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
CMS1_k127_5672736_3	264732.Moth_2471	2.559e-89	301.0	COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,42ETC@68295|Thermoanaerobacterales	186801|Clostridia	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
CMS1_k127_5672736_11	926569.ANT_18960	6.453e-33	134.0	COG0244@1|root,COG0244@2|Bacteria,2G6XJ@200795|Chloroflexi	200795|Chloroflexi	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
CMS1_k127_5672736_8	926550.CLDAP_14870	3.398e-38	146.0	COG0222@1|root,COG0222@2|Bacteria,2G700@200795|Chloroflexi	200795|Chloroflexi	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
CMS1_k127_5672736_0	1382306.JNIM01000001_gene1224	2.549e-290	914.0	COG1109@1|root,COG1208@1|root,COG1109@2|Bacteria,COG1208@2|Bacteria,2G65W@200795|Chloroflexi	200795|Chloroflexi	M	PFAM transferase hexapeptide repeat containing protein	-	-	2.7.7.13,5.4.2.8	ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II,PGM_PMM_III
CMS1_k127_5672736_1	926550.CLDAP_07930	1.632e-110	379.0	COG2720@1|root,COG2720@2|Bacteria,2G67R@200795|Chloroflexi	200795|Chloroflexi	V	PFAM VanW family protein	-	-	-	-	-	-	-	-	-	-	-	-	G5,PG_binding_4,VanW
CMS1_k127_5672736_6	1382306.JNIM01000001_gene1173	9.482e-63	228.0	COG2812@1|root,COG2812@2|Bacteria,2G6K3@200795|Chloroflexi	200795|Chloroflexi	L	DNA polymerase III, delta prime subunit	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
CMS1_k127_5672736_4	926550.CLDAP_14890	1.853e-83	287.0	COG1774@1|root,COG1774@2|Bacteria,2G6AJ@200795|Chloroflexi	200795|Chloroflexi	NU	PFAM PSP1 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PSP1
CMS1_k127_5672736_12	941824.TCEL_01888	3.241e-31	125.0	COG2359@1|root,COG2359@2|Bacteria,1V6G8@1239|Firmicutes,24MXY@186801|Clostridia,36KP7@31979|Clostridiaceae	186801|Clostridia	S	Stage V sporulation protein S	spoVS	-	-	ko:K06416	-	-	-	-	ko00000	-	-	-	SpoVS
CMS1_k127_5672736_2	1128421.JAGA01000001_gene2396	1.267e-98	331.0	COG2234@1|root,COG2234@2|Bacteria,2NP7A@2323|unclassified Bacteria	2|Bacteria	S	Peptidase M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
CMS1_k127_5672736_14	491915.Aflv_2645	3.726e-09	67.0	COG3764@1|root,COG3764@2|Bacteria,1V1RS@1239|Firmicutes,4HFWK@91061|Bacilli,21X69@150247|Anoxybacillus	91061|Bacilli	M	Sortase family	yhcS	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
CMS1_k127_5672736_10	383372.Rcas_0405	1.99e-33	143.0	COG3385@1|root,COG3385@2|Bacteria,2G8GC@200795|Chloroflexi,3768R@32061|Chloroflexia	32061|Chloroflexia	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
CMS1_k127_5672736_9	1128421.JAGA01000002_gene822	1.853e-33	134.0	COG1385@1|root,COG1385@2|Bacteria	2|Bacteria	J	rRNA (uridine-N3-)-methyltransferase activity	rsmE	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
CMS1_k127_5682359_0	1120950.KB892759_gene6225	2.096e-119	390.0	COG5285@1|root,COG5285@2|Bacteria,2HZP9@201174|Actinobacteria,4DTG4@85009|Propionibacteriales	201174|Actinobacteria	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
CMS1_k127_5682359_4	1120950.KB892746_gene3500	1.478e-26	124.0	COG1653@1|root,COG1653@2|Bacteria,2HFIW@201174|Actinobacteria,4DTUT@85009|Propionibacteriales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_1
CMS1_k127_5682359_1	1121346.KB899813_gene2159	1.1e-86	298.0	COG1175@1|root,COG1175@2|Bacteria,1TPTZ@1239|Firmicutes,4HB63@91061|Bacilli,26S91@186822|Paenibacillaceae	91061|Bacilli	G	ABC transporter permease	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
CMS1_k127_5682359_2	697281.Mahau_0771	3.515e-76	264.0	COG0395@1|root,COG0395@2|Bacteria,1TSAB@1239|Firmicutes,25C5T@186801|Clostridia,42JEU@68295|Thermoanaerobacterales	186801|Clostridia	P	COGs COG0395 ABC-type sugar transport system permease component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_5682359_3	867903.ThesuDRAFT_01348	1.315e-69	250.0	COG1032@1|root,COG1032@2|Bacteria,1UZQC@1239|Firmicutes,24PDA@186801|Clostridia	186801|Clostridia	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
CMS1_k127_5682812_1	502025.Hoch_6548	2.411e-113	377.0	COG0745@1|root,COG4251@1|root,COG0745@2|Bacteria,COG4251@2|Bacteria,1QVDV@1224|Proteobacteria,43CYW@68525|delta/epsilon subdivisions,2X872@28221|Deltaproteobacteria,2Z18H@29|Myxococcales	1224|Proteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GerE,HATPase_c,HisKA,PAS_4,Response_reg,SpoIIE
CMS1_k127_5682812_0	316274.Haur_3716	7.889e-122	400.0	2DBVK@1|root,2ZBBH@2|Bacteria,2G7SF@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5682813_3	1205680.CAKO01000029_gene4983	1.582e-80	279.0	COG0667@1|root,COG0667@2|Bacteria,1R5BH@1224|Proteobacteria,2TS0A@28211|Alphaproteobacteria,2JVHZ@204441|Rhodospirillales	204441|Rhodospirillales	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS1_k127_5682813_2	309801.trd_A0791	1.388e-99	345.0	COG0028@1|root,COG0028@2|Bacteria,2GA3W@200795|Chloroflexi,27Z3I@189775|Thermomicrobia	189775|Thermomicrobia	EH	Thiamine pyrophosphate enzyme, central domain	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS1_k127_5682813_1	278957.ABEA03000102_gene367	1.686e-107	354.0	COG1387@1|root,COG1387@2|Bacteria,46U67@74201|Verrucomicrobia,3K8DP@414999|Opitutae	414999|Opitutae	E	PHP domain	-	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
CMS1_k127_5682813_0	1382306.JNIM01000001_gene2968	5.172e-200	636.0	COG1070@1|root,COG1070@2|Bacteria,2G7ND@200795|Chloroflexi	200795|Chloroflexi	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
CMS1_k127_5682813_4	948106.AWZT01000096_gene4620	1.096e-52	195.0	COG1028@1|root,COG1028@2|Bacteria,1P3AE@1224|Proteobacteria,2VN49@28216|Betaproteobacteria,1KGKH@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS1_k127_5682813_8	1303518.CCALI_00247	1.291e-21	106.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	ydzE	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS1_k127_5682813_7	926550.CLDAP_06330	2.687e-48	178.0	COG2606@1|root,COG2606@2|Bacteria,2G931@200795|Chloroflexi	200795|Chloroflexi	S	Aminoacyl-tRNA editing domain	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
CMS1_k127_5682813_6	307480.IW16_08765	2.03e-50	191.0	2DB8K@1|root,2Z7S1@2|Bacteria,4NI7A@976|Bacteroidetes,1I0N2@117743|Flavobacteriia,3ZRFB@59732|Chryseobacterium	976|Bacteroidetes	I	Streptomycin adenylyltransferase	aadK	-	-	ko:K05593	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Adenyl_transf
CMS1_k127_5682813_5	485913.Krac_5165	1.146e-52	194.0	COG2320@1|root,COG2320@2|Bacteria	2|Bacteria	Q	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	-	-	-	-	-	-	-	-	-	-	-	-	GrpB
CMS1_k127_5694100_2	1122132.AQYH01000004_gene1674	1.713e-98	328.0	COG1173@1|root,COG1173@2|Bacteria,1R4DJ@1224|Proteobacteria,2U44U@28211|Alphaproteobacteria,4B9Q2@82115|Rhizobiaceae	28211|Alphaproteobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_5694100_1	1122132.AQYH01000004_gene1675	7.199e-125	407.0	COG0601@1|root,COG0601@2|Bacteria,1QDMV@1224|Proteobacteria,2TTGN@28211|Alphaproteobacteria,4B6XV@82115|Rhizobiaceae	28211|Alphaproteobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_5694100_0	391735.Veis_0531	3.622e-233	738.0	COG0747@1|root,COG0747@2|Bacteria,1R49R@1224|Proteobacteria	1224|Proteobacteria	E	ABC-Type Dipeptide Transport System Periplasmic Component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_5694100_3	926569.ANT_16820	1.165e-62	232.0	COG1408@1|root,COG1408@2|Bacteria,2G6VC@200795|Chloroflexi	200795|Chloroflexi	S	PFAM metallophosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
CMS1_k127_5694100_4	309807.SRU_2151	2.423e-50	183.0	2DKY3@1|root,32UFX@2|Bacteria	2|Bacteria	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
CMS1_k127_5694100_5	326427.Cagg_2931	5.249e-17	82.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2G790@200795|Chloroflexi,3750C@32061|Chloroflexia	32061|Chloroflexia	T	SMART protein phosphatase 2C domain protein	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF_2,GAF_3,SpoIIE
CMS1_k127_5703589_2	661478.OP10G_0033	1.011e-23	109.0	2F765@1|root,2ZKNT@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5703589_1	383372.Rcas_2983	8.811e-44	162.0	COG0633@1|root,COG0633@2|Bacteria,2G8VJ@200795|Chloroflexi,375ZJ@32061|Chloroflexia	32061|Chloroflexia	C	PFAM ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Fer2
CMS1_k127_5703589_3	479434.Sthe_1215	6.835e-21	94.0	COG0268@1|root,COG0268@2|Bacteria,2G7AK@200795|Chloroflexi,27YPB@189775|Thermomicrobia	189775|Thermomicrobia	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
CMS1_k127_5703589_0	383372.Rcas_0997	4.868e-83	281.0	COG0745@1|root,COG0745@2|Bacteria,2G6A5@200795|Chloroflexi,3752X@32061|Chloroflexia	32061|Chloroflexia	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_5705219_0	215803.DB30_8412	1.368e-200	663.0	COG0457@1|root,COG0515@1|root,COG3899@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,COG3899@2|Bacteria,1PEJF@1224|Proteobacteria,433Y5@68525|delta/epsilon subdivisions,2X2KM@28221|Deltaproteobacteria,2YXZ5@29|Myxococcales	28221|Deltaproteobacteria	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
CMS1_k127_5705219_2	1382315.JPOI01000001_gene1506	7.641e-103	346.0	COG1062@1|root,COG1062@2|Bacteria,1TP8E@1239|Firmicutes,4HAH9@91061|Bacilli,1WG1U@129337|Geobacillus	91061|Bacilli	C	Zinc-binding dehydrogenase	-	-	1.1.1.1,1.1.1.284,1.1.1.90	ko:K00055,ko:K00121	ko00010,ko00071,ko00350,ko00360,ko00622,ko00623,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00360,map00622,map00623,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	M00537,M00538	R00623,R00754,R01763,R02124,R02611,R04304,R04880,R05233,R05234,R05282,R05347,R05348,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_5705219_1	1499967.BAYZ01000182_gene4442	1.206e-124	407.0	COG0673@1|root,COG0673@2|Bacteria,2NQJN@2323|unclassified Bacteria	2|Bacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	iolG	-	1.1.1.18,1.1.1.369	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	-	R01183,R09951	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_5707483_5	35841.BT1A1_0987	8.884e-44	171.0	COG0673@1|root,COG0673@2|Bacteria,1TQ72@1239|Firmicutes,4HCS4@91061|Bacilli,1ZCPA@1386|Bacillus	91061|Bacilli	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_5707483_4	926549.KI421517_gene1645	1.854e-57	210.0	COG1082@1|root,COG1082@2|Bacteria,4NK9X@976|Bacteroidetes,47KBS@768503|Cytophagia	976|Bacteroidetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
CMS1_k127_5707483_3	1123023.JIAI01000018_gene2470	3.385e-96	324.0	COG5285@1|root,COG5285@2|Bacteria	2|Bacteria	Q	dioxygenase activity	-	-	-	ko:K18565	ko00332,ko01130,map00332,map01130	-	R10740,R10741,R10742	RC03267,RC03268,RC03269	ko00000,ko00001,ko01000	-	-	-	PhyH
CMS1_k127_5707483_7	333138.LQ50_24170	3.541e-32	128.0	COG2146@1|root,COG2146@2|Bacteria,1TU1F@1239|Firmicutes,4IM3H@91061|Bacilli,1ZJ0X@1386|Bacillus	91061|Bacilli	P	Rieske-like [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
CMS1_k127_5707483_0	1449063.JMLS01000021_gene758	1.103e-111	372.0	COG2159@1|root,COG2159@2|Bacteria,1UZAH@1239|Firmicutes,4HA5S@91061|Bacilli,26SJA@186822|Paenibacillaceae	91061|Bacilli	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CMS1_k127_5707483_2	525904.Tter_2216	2.438e-96	323.0	COG0395@1|root,COG0395@2|Bacteria,2NPII@2323|unclassified Bacteria	2|Bacteria	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02026,ko:K05815	ko02010,map02010	M00198,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.3	-	-	BPD_transp_1
CMS1_k127_5707483_1	697281.Mahau_0018	5.951e-98	329.0	COG1175@1|root,COG1175@2|Bacteria,1TPTZ@1239|Firmicutes,2492R@186801|Clostridia,42JBI@68295|Thermoanaerobacterales	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_5707483_6	1385511.N783_18665	2.617e-40	162.0	COG1653@1|root,COG1653@2|Bacteria,1TRIH@1239|Firmicutes,4H9MG@91061|Bacilli,2YBH4@289201|Pontibacillus	91061|Bacilli	G	Sugar ABC transporter substrate-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1
CMS1_k127_5709980_6	304371.MCP_2710	2.001e-10	66.0	COG0438@1|root,arCOG01403@2157|Archaea,2XTRH@28890|Euryarchaeota	28890|Euryarchaeota	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS1_k127_5709980_5	326427.Cagg_0803	2.48e-14	86.0	COG4409@1|root,COG4409@2|Bacteria,2G76D@200795|Chloroflexi,3763D@32061|Chloroflexia	32061|Chloroflexia	M	BNR repeat-containing family member	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
CMS1_k127_5709980_3	43989.cce_2800	4.288e-49	192.0	COG0438@1|root,COG0438@2|Bacteria,1G271@1117|Cyanobacteria,3KH3R@43988|Cyanothece	1117|Cyanobacteria	H	Glycosyl transferase 4-like domain	icsA	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
CMS1_k127_5709980_2	596151.DesfrDRAFT_0608	1.097e-55	215.0	COG3379@1|root,COG3379@2|Bacteria,1NBJ6@1224|Proteobacteria,42XTF@68525|delta/epsilon subdivisions,2WSZG@28221|Deltaproteobacteria,2M8ME@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
CMS1_k127_5709980_0	1173028.ANKO01000159_gene5217	8.97e-148	479.0	COG1134@1|root,COG1134@2|Bacteria,1G28R@1117|Cyanobacteria,1H8CS@1150|Oscillatoriales	1117|Cyanobacteria	GM	ABC-type polysaccharide polyol phosphate transport system ATPase component	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
CMS1_k127_5709980_1	237368.SCABRO_01358	7.782e-129	417.0	COG1682@1|root,COG1682@2|Bacteria,2IYXC@203682|Planctomycetes	203682|Planctomycetes	U	COG1682 ABC-type polysaccharide polyol phosphate export systems, permease component	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
CMS1_k127_5709980_4	1147.D082_25660	1.35e-14	79.0	COG2931@1|root,COG3204@1|root,COG3210@1|root,COG5184@1|root,COG2931@2|Bacteria,COG3204@2|Bacteria,COG3210@2|Bacteria,COG5184@2|Bacteria,1G5KY@1117|Cyanobacteria,1H6DE@1142|Synechocystis	1117|Cyanobacteria	QU	Cadherin repeats.	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,Calx-beta,HemolysinCabind,VCBS
CMS1_k127_5710615_0	383372.Rcas_2847	4.454e-157	505.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_5710615_4	485913.Krac_5563	3.113e-31	135.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
CMS1_k127_5710615_3	383372.Rcas_2583	5.134e-70	254.0	COG2211@1|root,COG2211@2|Bacteria,2GA8Z@200795|Chloroflexi,3782P@32061|Chloroflexia	32061|Chloroflexia	G	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_5710615_2	1132509.C447_13097	8.363e-102	342.0	COG1312@1|root,arCOG05324@2157|Archaea,2XU9K@28890|Euryarchaeota,23UJN@183963|Halobacteria	183963|Halobacteria	G	COG1312 D-mannonate dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	UxuA
CMS1_k127_5710615_1	697281.Mahau_2566	7.059e-110	362.0	COG1175@1|root,COG1175@2|Bacteria,1TPTZ@1239|Firmicutes,2492R@186801|Clostridia,42FXR@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_5710615_5	697281.Mahau_2568	3.866e-18	85.0	COG0395@1|root,COG0395@2|Bacteria,1TSAB@1239|Firmicutes,25C5T@186801|Clostridia,42JEU@68295|Thermoanaerobacterales	186801|Clostridia	P	COGs COG0395 ABC-type sugar transport system permease component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_5717493_9	102125.Xen7305DRAFT_00026230	1.647e-11	65.0	2E2ED@1|root,32XIY@2|Bacteria,1G5KK@1117|Cyanobacteria,3VM6E@52604|Pleurocapsales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5717493_4	118168.MC7420_4493	2.293e-45	167.0	COG1403@1|root,COG1403@2|Bacteria,1G7ZB@1117|Cyanobacteria,1HC2V@1150|Oscillatoriales	1117|Cyanobacteria	L	PFAM HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH
CMS1_k127_5717493_8	1173027.Mic7113_4389	3.467e-18	88.0	2E16Z@1|root,32WMU@2|Bacteria,1G8XR@1117|Cyanobacteria,1HCB6@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5717493_5	357808.RoseRS_0376	3.72e-39	149.0	2A4IP@1|root,30T58@2|Bacteria,2GB1J@200795|Chloroflexi,377R1@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5717493_3	309799.DICTH_0356	1.411e-53	198.0	COG0637@1|root,COG0637@2|Bacteria	2|Bacteria	S	phosphonoacetaldehyde hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
CMS1_k127_5717493_7	1170562.Cal6303_4488	4.77e-20	95.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1G1PE@1117|Cyanobacteria,1HJAX@1161|Nostocales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
CMS1_k127_5717493_0	926550.CLDAP_39200	1.419e-155	503.0	COG1249@1|root,COG1249@2|Bacteria,2G5MR@200795|Chloroflexi	200795|Chloroflexi	C	Pyridine nucleotide-disulphide oxidoreductase dimerisation region	lpd	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
CMS1_k127_5717493_6	926550.CLDAP_03750	5.915e-22	106.0	2EV3Q@1|root,33NIR@2|Bacteria,2G9SC@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5717493_1	760568.Desku_3293	2.452e-89	301.0	COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,248JN@186801|Clostridia,260CH@186807|Peptococcaceae	186801|Clostridia	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
CMS1_k127_5717493_10	1042163.BRLA_c039360	0.0004335	47.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,1V3V0@1239|Firmicutes,4HGZD@91061|Bacilli,26TH1@186822|Paenibacillaceae	91061|Bacilli	H	molybdopterin converting factor	moaE	-	2.8.1.12	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
CMS1_k127_5717493_2	232346.JHQL01000001_gene2407	1.243e-58	209.0	COG2094@1|root,COG2094@2|Bacteria,1RE0A@1224|Proteobacteria,1S9CM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Belongs to the DNA glycosylase MPG family	-	GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
CMS1_k127_5719383_5	926569.ANT_06190	2.793e-14	78.0	COG2835@1|root,COG2835@2|Bacteria	2|Bacteria	EG	tetraacyldisaccharide 4'-kinase activity	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Methyltransf_11,Methyltransf_25,Trm112p
CMS1_k127_5719383_3	526227.Mesil_0168	2.402e-31	136.0	COG4635@1|root,COG4635@2|Bacteria	2|Bacteria	CH	menaquinone-dependent protoporphyrinogen oxidase activity	-	-	1.3.5.3	ko:K00230	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R09489	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavodoxin_5
CMS1_k127_5719383_4	666686.B1NLA3E_11550	3.128e-19	100.0	COG1357@1|root,COG1357@2|Bacteria,1VCZ3@1239|Firmicutes	1239|Firmicutes	S	Pentapeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide,Pentapeptide_4
CMS1_k127_5719383_2	331869.BAL199_10420	1.607e-157	512.0	COG5598@1|root,COG5598@2|Bacteria,1MWJN@1224|Proteobacteria,2TR0V@28211|Alphaproteobacteria,4BP93@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	H	Trimethylamine methyltransferase (MTTB)	mttB2	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
CMS1_k127_5719383_0	42256.RradSPS_0632	3.644e-179	568.0	COG0404@1|root,COG0404@2|Bacteria,2GJ47@201174|Actinobacteria	201174|Actinobacteria	E	The glycine cleavage system catalyzes the degradation of glycine	-	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_4,GCV_T,GCV_T_C,Pyr_redox_2
CMS1_k127_5719383_1	42256.RradSPS_0633	6.319e-172	549.0	COG0665@1|root,COG0665@2|Bacteria,2I9WR@201174|Actinobacteria,4CR0T@84995|Rubrobacteria	84995|Rubrobacteria	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
CMS1_k127_5728654_2	865861.AZSU01000002_gene2518	3.392e-72	252.0	COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,248HE@186801|Clostridia,36EDX@31979|Clostridiaceae	186801|Clostridia	L	Hydrolase, TatD family	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
CMS1_k127_5728654_1	926569.ANT_14700	4.14e-82	284.0	COG0142@1|root,COG0142@2|Bacteria,2G6IZ@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the FPP GGPP synthase family	hepT	-	2.5.1.30,2.5.1.90	ko:K00805,ko:K02523	ko00900,ko01110,map00900,map01110	-	R09247,R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
CMS1_k127_5728654_0	926569.ANT_22690	3.117e-126	415.0	COG1132@1|root,COG1132@2|Bacteria,2G7KM@200795|Chloroflexi	200795|Chloroflexi	P	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS1_k127_5733735_1	485913.Krac_3018	1.657e-67	234.0	COG1132@1|root,COG1132@2|Bacteria,2G86M@200795|Chloroflexi	2|Bacteria	P	COGs COG1132 ABC-type multidrug transport system ATPase and permease components	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS1_k127_5733735_3	485913.Krac_4723	2.325e-35	140.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS1_k127_5733735_0	1382306.JNIM01000001_gene79	3.645e-90	314.0	COG2518@1|root,COG2518@2|Bacteria,2G6NG@200795|Chloroflexi	2|Bacteria	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
CMS1_k127_5733735_2	1094508.Tsac_1765	1.129e-37	148.0	COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,24I1G@186801|Clostridia,42GJV@68295|Thermoanaerobacterales	186801|Clostridia	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
CMS1_k127_5733735_4	756499.Desde_3244	1.429e-12	68.0	COG1837@1|root,COG1837@2|Bacteria,1VEG7@1239|Firmicutes,24QKN@186801|Clostridia,262RX@186807|Peptococcaceae	186801|Clostridia	S	Belongs to the UPF0109 family	ylqC	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
CMS1_k127_5735206_3	1128421.JAGA01000002_gene142	1.452e-115	381.0	COG1894@1|root,COG1894@2|Bacteria,2NNM1@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
CMS1_k127_5735206_18	324602.Caur_2900	3.134e-38	149.0	COG1905@1|root,COG1905@2|Bacteria,2G70Y@200795|Chloroflexi,375IT@32061|Chloroflexia	32061|Chloroflexia	C	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
CMS1_k127_5735206_1	926550.CLDAP_08740	4.271e-198	633.0	COG0649@1|root,COG0852@1|root,COG0649@2|Bacteria,COG0852@2|Bacteria,2G5MM@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
CMS1_k127_5735206_9	926550.CLDAP_08750	1.491e-65	229.0	COG0377@1|root,COG0377@2|Bacteria,2G6GB@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB1	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
CMS1_k127_5735206_20	671143.DAMO_2700	5.321e-35	136.0	COG0838@1|root,COG0838@2|Bacteria,2NPTW@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
CMS1_k127_5735206_16	479434.Sthe_0382	4.02e-42	162.0	COG0242@1|root,COG0242@2|Bacteria,2G6VE@200795|Chloroflexi,27YB2@189775|Thermomicrobia	189775|Thermomicrobia	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
CMS1_k127_5735206_17	357808.RoseRS_3026	1.876e-38	164.0	COG0745@1|root,COG2203@1|root,COG2204@1|root,COG4191@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,COG2204@2|Bacteria,COG4191@2|Bacteria,2G7Y4@200795|Chloroflexi,374VX@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA,PAS_4,Response_reg
CMS1_k127_5735206_11	1128421.JAGA01000003_gene3534	3.005e-61	220.0	COG0406@1|root,COG0406@2|Bacteria	2|Bacteria	G	alpha-ribazole phosphatase activity	-	-	3.1.3.3,3.1.3.73,5.4.2.12	ko:K02226,ko:K15634,ko:K22305	ko00010,ko00260,ko00680,ko00860,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map00860,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00122	R00582,R01518,R04594,R11173	RC00017,RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
CMS1_k127_5735206_15	765420.OSCT_0511	1.768e-42	161.0	298YA@1|root,2ZW25@2|Bacteria,2G6UQ@200795|Chloroflexi,375RV@32061|Chloroflexia	32061|Chloroflexia	S	Protein of unknown function (DUF3090)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3090
CMS1_k127_5735206_8	357808.RoseRS_0006	1.46e-74	258.0	COG5032@1|root,COG5032@2|Bacteria,2G6FZ@200795|Chloroflexi,375HF@32061|Chloroflexia	32061|Chloroflexia	BDLTU	phosphatidylinositol kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	PI3_PI4_kinase
CMS1_k127_5735206_25	1121926.AXWO01000028_gene3919	1.207e-17	86.0	COG2331@1|root,COG2331@2|Bacteria,2IQHE@201174|Actinobacteria,4F019@85014|Glycomycetales	201174|Actinobacteria	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
CMS1_k127_5735206_19	479434.Sthe_0471	1.802e-36	141.0	COG0335@1|root,COG0335@2|Bacteria,2G6W0@200795|Chloroflexi,27YD2@189775|Thermomicrobia	189775|Thermomicrobia	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
CMS1_k127_5735206_13	269799.Gmet_2865	7.887e-54	199.0	COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,42REG@68525|delta/epsilon subdivisions,2WNK2@28221|Deltaproteobacteria,43SXH@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DUF208,RNase_HII
CMS1_k127_5735206_26	1029824.AFID01000005_gene747	2.722e-12	73.0	COG0745@1|root,COG0745@2|Bacteria,2IQWH@201174|Actinobacteria,1WA4T@1268|Micrococcaceae	201174|Actinobacteria	T	cheY-homologous receiver domain	ompR	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS1_k127_5735206_10	1128421.JAGA01000003_gene2967	2.807e-61	240.0	COG0642@1|root,COG2205@2|Bacteria	1128421.JAGA01000003_gene2967|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5735206_7	118168.MC7420_6482	2.188e-89	324.0	COG5002@1|root,COG5002@2|Bacteria,1GQB3@1117|Cyanobacteria,1H7YF@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	ko:K11959	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	HAMP,HATPase_c,HisKA,PAS_4
CMS1_k127_5735206_4	313612.L8106_21529	1.721e-101	340.0	COG3221@1|root,COG3221@2|Bacteria,1G2AZ@1117|Cyanobacteria,1HAC9@1150|Oscillatoriales	1117|Cyanobacteria	P	COG3221 ABC-type phosphate phosphonate transport system, periplasmic component	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
CMS1_k127_5735206_5	118168.MC7420_6482	6.502e-95	332.0	COG5002@1|root,COG5002@2|Bacteria,1GQB3@1117|Cyanobacteria,1H7YF@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	ko:K11959	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	HAMP,HATPase_c,HisKA,PAS_4
CMS1_k127_5735206_6	313612.L8106_21529	1.329e-94	319.0	COG3221@1|root,COG3221@2|Bacteria,1G2AZ@1117|Cyanobacteria,1HAC9@1150|Oscillatoriales	1117|Cyanobacteria	P	COG3221 ABC-type phosphate phosphonate transport system, periplasmic component	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
CMS1_k127_5735206_2	383372.Rcas_2639	2.143e-132	443.0	COG0642@1|root,COG2205@2|Bacteria,2GBI0@200795|Chloroflexi,3766M@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,HisKA_7TM,PAS_4
CMS1_k127_5735206_12	926550.CLDAP_14940	6.018e-55	199.0	COG2178@1|root,COG2178@2|Bacteria,2G6RW@200795|Chloroflexi	200795|Chloroflexi	J	PFAM Translin	-	-	-	ko:K07477	-	-	-	-	ko00000	-	-	-	-
CMS1_k127_5735206_27	765420.OSCT_0447	7.013e-07	62.0	COG0457@1|root,COG3170@1|root,COG0457@2|Bacteria,COG3170@2|Bacteria,2GBRC@200795|Chloroflexi,375MT@32061|Chloroflexia	32061|Chloroflexia	NU	Type IV pilus biogenesis stability protein PilW	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5735206_23	926550.CLDAP_10230	4.564e-21	108.0	COG1376@1|root,COG1388@1|root,COG1376@2|Bacteria,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	ratA	-	3.5.1.104	ko:K21449,ko:K22278	-	-	-	-	ko00000,ko01000,ko02000	1.B.40.2	-	-	LysM,PG_binding_1,PG_binding_4,YkuD
CMS1_k127_5735206_24	926550.CLDAP_18910	1.17e-19	100.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	BsuPI,Glyco_hydro_19,LysM,PG_binding_1,Peptidase_C39_2,SLT
CMS1_k127_5735206_22	926569.ANT_19040	3.132e-24	104.0	2EUFH@1|root,31CAS@2|Bacteria,2G9NZ@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5735206_0	1128421.JAGA01000002_gene1199	6.984e-233	732.0	COG0318@1|root,COG0318@2|Bacteria,2NPH9@2323|unclassified Bacteria	2|Bacteria	IQ	COGs COG0318 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
CMS1_k127_5735206_21	272569.rrnAC2123	8.088e-31	135.0	arCOG08113@1|root,arCOG08113@2157|Archaea,2XV1B@28890|Euryarchaeota,23TAX@183963|Halobacteria	183963|Halobacteria	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	BNR
CMS1_k127_5740425_7	1198232.CYCME_1431	7.968e-44	175.0	COG4745@1|root,COG4745@2|Bacteria,1P6CQ@1224|Proteobacteria	1224|Proteobacteria	O	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5740425_1	357808.RoseRS_3820	1.472e-146	496.0	28HGC@1|root,30IRW@2|Bacteria,2GA7N@200795|Chloroflexi,376R6@32061|Chloroflexia	32061|Chloroflexia	S	Bacterial cellulose synthase subunit	-	-	-	ko:K20541	-	-	-	-	ko00000,ko02000	4.D.3.1.6	-	-	BcsB
CMS1_k127_5740425_2	1128421.JAGA01000002_gene528	9.076e-142	459.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
CMS1_k127_5740425_4	1128421.JAGA01000002_gene527	3.37e-114	382.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	2.4.1.342	ko:K16148	ko00500,ko01100,map00500,map01100	-	R02421,R11530	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
CMS1_k127_5740425_0	419610.Mext_3554	1.047e-227	722.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2TSCY@28211|Alphaproteobacteria,1JTWU@119045|Methylobacteriaceae	28211|Alphaproteobacteria	E	TIGRFAM asparagine synthase (glutamine-hydrolyzing)	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
CMS1_k127_5740425_8	886293.Sinac_3903	0.0004362	43.0	COG2264@1|root,COG2264@2|Bacteria	2|Bacteria	J	protein methyltransferase activity	prmA	-	2.1.1.222,2.1.1.64	ko:K00568,ko:K02687	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000,ko03009	-	-	-	Methyltransf_12,Methyltransf_21,Methyltransf_23,Methyltransf_25,Methyltransf_31,PrmA
CMS1_k127_5740425_6	316274.Haur_3581	1.529e-73	263.0	COG0438@1|root,COG0438@2|Bacteria,2GBA1@200795|Chloroflexi,377MX@32061|Chloroflexia	32061|Chloroflexia	H	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS1_k127_5740425_3	316274.Haur_3580	1.717e-119	400.0	COG2244@1|root,COG2244@2|Bacteria,2G7NK@200795|Chloroflexi,3761V@32061|Chloroflexia	32061|Chloroflexia	S	PFAM polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_3,Polysacc_synt_C
CMS1_k127_5740425_5	316274.Haur_3579	1.388e-95	331.0	COG3307@1|root,COG3307@2|Bacteria,2GB55@200795|Chloroflexi,377AJ@32061|Chloroflexia	32061|Chloroflexia	M	PFAM O-antigen polymerase	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
CMS1_k127_5745318_5	1047013.AQSP01000138_gene1054	1.004e-05	51.0	2DTK7@1|root,33KQU@2|Bacteria,2NRAS@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5745318_0	118161.KB235922_gene3387	1.349e-123	405.0	COG1215@1|root,COG1215@2|Bacteria,1GQT8@1117|Cyanobacteria	1117|Cyanobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS1_k127_5745318_1	1198232.CYCME_1453	1.749e-93	325.0	COG1232@1|root,COG1232@2|Bacteria,1QX3T@1224|Proteobacteria,1T3RT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
CMS1_k127_5745318_2	1397696.KK211189_gene957	1.602e-35	151.0	COG1215@1|root,COG1215@2|Bacteria,1TRCI@1239|Firmicutes,4HAAK@91061|Bacilli,3WEGQ@539002|Bacillales incertae sedis	91061|Bacilli	M	Glycosyl transferase family group 2	ydaM	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
CMS1_k127_5745318_3	765912.Thimo_3569	5.109e-21	106.0	COG1216@1|root,COG1216@2|Bacteria,1N5RX@1224|Proteobacteria,1SH90@1236|Gammaproteobacteria,1WZUQ@135613|Chromatiales	135613|Chromatiales	S	Uncharacterised nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
CMS1_k127_5745318_4	43989.cce_4998	2.417e-10	68.0	COG4113@1|root,COG4113@2|Bacteria,1G7F7@1117|Cyanobacteria	1117|Cyanobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
CMS1_k127_5745881_3	1329516.JPST01000020_gene2268	8.621e-34	136.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1UYA0@1239|Firmicutes,4HD4S@91061|Bacilli,27CKJ@186824|Thermoactinomycetaceae	91061|Bacilli	GT	PEP-utilising enzyme, mobile domain	-	-	-	-	-	-	-	-	-	-	-	-	PEP-utilizers,PPDK_N
CMS1_k127_5745881_4	292415.Tbd_2380	2.866e-29	127.0	COG0730@1|root,COG0730@2|Bacteria,1MX4T@1224|Proteobacteria,2VRZJ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
CMS1_k127_5745881_1	926550.CLDAP_01280	7.484e-83	291.0	COG0477@1|root,COG2814@2|Bacteria,2GBNR@200795|Chloroflexi	200795|Chloroflexi	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5745881_2	314266.SKA58_03555	1.564e-56	205.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,2TR9H@28211|Alphaproteobacteria,2K3M8@204457|Sphingomonadales	204457|Sphingomonadales	C	Cysteine-rich domain	-	-	-	ko:K11473,ko:K18928	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_7
CMS1_k127_5745881_0	266117.Rxyl_2994	1.152e-128	426.0	COG0247@1|root,COG1139@1|root,COG0247@2|Bacteria,COG1139@2|Bacteria,2GJDR@201174|Actinobacteria,4CPII@84995|Rubrobacteria	84995|Rubrobacteria	C	Domain of unknown function (DUF3390)	-	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_8,LUD_dom
CMS1_k127_5745881_5	1121428.DESHY_50048___1	1.822e-23	108.0	COG1556@1|root,COG1556@2|Bacteria,1VATZ@1239|Firmicutes,24P3S@186801|Clostridia,262FK@186807|Peptococcaceae	186801|Clostridia	C	PFAM Uncharacterised ACR, YkgG family COG1556	-	-	-	ko:K00782	-	-	-	-	ko00000	-	-	-	LUD_dom
CMS1_k127_5745881_6	765420.OSCT_2861	1.098e-05	48.0	COG0823@1|root,COG0823@2|Bacteria,2GAJ0@200795|Chloroflexi,376FZ@32061|Chloroflexia	32061|Chloroflexia	U	PFAM WD40 domain protein beta Propeller	-	-	-	-	-	-	-	-	-	-	-	-	PD40
CMS1_k127_5746571_6	180281.CPCC7001_2429	7.273e-11	68.0	COG1042@1|root,COG1670@1|root,COG1042@2|Bacteria,COG1670@2|Bacteria,1G2D3@1117|Cyanobacteria,22TMZ@167375|Cyanobium	1117|Cyanobacteria	CJ	CoA binding domain	-	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
CMS1_k127_5746571_0	754035.Mesau_02654	1.574e-133	452.0	COG2267@1|root,COG3629@1|root,COG2267@2|Bacteria,COG3629@2|Bacteria,1NIJG@1224|Proteobacteria,2U09P@28211|Alphaproteobacteria,43PM5@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	IT	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,BTAD,Hydrolase_4,Trans_reg_C
CMS1_k127_5746571_5	1297865.APJD01000026_gene2438	1.994e-26	126.0	COG2114@1|root,COG2114@2|Bacteria,1P8ZU@1224|Proteobacteria,2TRC7@28211|Alphaproteobacteria,3JUCZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
CMS1_k127_5746571_2	1382356.JQMP01000004_gene492	6.683e-121	398.0	COG1506@1|root,COG1506@2|Bacteria,2G8QF@200795|Chloroflexi,27YT1@189775|Thermomicrobia	189775|Thermomicrobia	E	Alpha/beta hydrolase of unknown function (DUF1100)	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
CMS1_k127_5746571_3	1128421.JAGA01000003_gene3248	2.186e-77	276.0	COG0477@1|root,COG2814@2|Bacteria,2NQ08@2323|unclassified Bacteria	2|Bacteria	EGP	MFS_1 like family	-	-	-	ko:K08151,ko:K08153	-	M00668,M00717	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75,2.A.1.2.8	-	-	MFS_1,MFS_1_like,Sugar_tr
CMS1_k127_5746571_1	1122176.KB903576_gene5010	3.336e-124	420.0	COG2133@1|root,COG4886@1|root,COG2133@2|Bacteria,COG4886@2|Bacteria,4NF0B@976|Bacteroidetes,1IVY8@117747|Sphingobacteriia	976|Bacteroidetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,GSDH
CMS1_k127_5746571_4	525904.Tter_0620	1.669e-38	149.0	COG2006@1|root,COG2006@2|Bacteria	2|Bacteria	U	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088,DUF362
CMS1_k127_5748738_2	42256.RradSPS_0358	2.48e-139	468.0	COG2909@1|root,COG2909@2|Bacteria,2HENR@201174|Actinobacteria,4CPC9@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,AAA_22,GerE
CMS1_k127_5748738_11	316274.Haur_3775	6.439e-22	104.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G88D@200795|Chloroflexi,374V1@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA_3
CMS1_k127_5748738_10	1242864.D187_004967	1.224e-27	127.0	COG1388@1|root,COG3179@1|root,COG1388@2|Bacteria,COG3179@2|Bacteria,1MYUR@1224|Proteobacteria,42UGP@68525|delta/epsilon subdivisions,2WWB8@28221|Deltaproteobacteria,2YZ5E@29|Myxococcales	28221|Deltaproteobacteria	M	Chitinase class I	-	-	-	ko:K03791	-	-	-	-	ko00000	-	GH19	-	Glyco_hydro_19,LysM,PG_binding_1
CMS1_k127_5748738_1	926550.CLDAP_32030	5.226e-144	471.0	COG0673@1|root,COG0673@2|Bacteria,2G7RI@200795|Chloroflexi	200795|Chloroflexi	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_5748738_13	73044.JNXP01000005_gene248	2.096e-11	68.0	COG1734@1|root,COG1734@2|Bacteria,2GJBE@201174|Actinobacteria	201174|Actinobacteria	T	Transcriptional regulator, TraR DksA family	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
CMS1_k127_5748738_3	383372.Rcas_2015	2.21e-93	320.0	COG0539@1|root,COG0539@2|Bacteria,2G656@200795|Chloroflexi,3757Z@32061|Chloroflexia	32061|Chloroflexia	J	PFAM RNA binding S1 domain protein	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
CMS1_k127_5748738_6	313612.L8106_21167	2.279e-84	296.0	COG2823@1|root,COG2823@2|Bacteria,1G9YH@1117|Cyanobacteria	1117|Cyanobacteria	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
CMS1_k127_5748738_14	1121930.AQXG01000003_gene2608	1.512e-05	48.0	COG1048@1|root,COG1048@2|Bacteria,4NDZT@976|Bacteroidetes,1INUB@117747|Sphingobacteriia	976|Bacteroidetes	C	aconitate hydratase	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
CMS1_k127_5748738_12	472759.Nhal_1482	5.725e-20	92.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,1RN5I@1236|Gammaproteobacteria,1WZYZ@135613|Chromatiales	135613|Chromatiales	C	aconitate hydratase	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
CMS1_k127_5748738_0	502025.Hoch_0382	9.538e-155	500.0	COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,42PFG@68525|delta/epsilon subdivisions,2WKPM@28221|Deltaproteobacteria,2YTUX@29|Myxococcales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	ndh2	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
CMS1_k127_5748738_4	926569.ANT_09310	9.1e-87	294.0	COG0745@1|root,COG0745@2|Bacteria,2G6A5@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_5748738_7	502025.Hoch_6548	2.768e-79	277.0	COG0745@1|root,COG4251@1|root,COG0745@2|Bacteria,COG4251@2|Bacteria,1QVDV@1224|Proteobacteria,43CYW@68525|delta/epsilon subdivisions,2X872@28221|Deltaproteobacteria,2Z18H@29|Myxococcales	1224|Proteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GerE,HATPase_c,HisKA,PAS_4,Response_reg,SpoIIE
CMS1_k127_5748738_8	502025.Hoch_6548	7.357e-76	267.0	COG0745@1|root,COG4251@1|root,COG0745@2|Bacteria,COG4251@2|Bacteria,1QVDV@1224|Proteobacteria,43CYW@68525|delta/epsilon subdivisions,2X872@28221|Deltaproteobacteria,2Z18H@29|Myxococcales	1224|Proteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GerE,HATPase_c,HisKA,PAS_4,Response_reg,SpoIIE
CMS1_k127_5748738_5	1499967.BAYZ01000027_gene1810	6.195e-85	317.0	COG2203@1|root,COG3920@1|root,COG2203@2|Bacteria,COG3920@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_9,Response_reg
CMS1_k127_5748738_9	1121422.AUMW01000024_gene286	1.452e-28	135.0	COG0642@1|root,COG3829@1|root,COG4191@1|root,COG5002@1|root,COG2205@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,COG5002@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,264H3@186807|Peptococcaceae	186801|Clostridia	T	Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Fe_hyd_lg_C,GAF_2,HATPase_c,HisKA,PAS_9,Response_reg,dCache_3,sCache_3_3
CMS1_k127_5750016_1	383372.Rcas_2454	3.941e-127	417.0	COG0747@1|root,COG0747@2|Bacteria,2G84E@200795|Chloroflexi	200795|Chloroflexi	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_5750016_0	383372.Rcas_2455	4.8e-168	533.0	COG4608@1|root,COG4608@2|Bacteria,2G5R5@200795|Chloroflexi,3754I@32061|Chloroflexia	200795|Chloroflexi	P	TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
CMS1_k127_5750016_3	316274.Haur_0021	1.185e-62	228.0	COG3424@1|root,COG3424@2|Bacteria	2|Bacteria	Q	synthase	bcsA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006629,GO:0006725,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009273,GO:0009698,GO:0009699,GO:0009714,GO:0009715,GO:0009987,GO:0016020,GO:0016043,GO:0019438,GO:0019748,GO:0022607,GO:0032991,GO:0034081,GO:0042180,GO:0042181,GO:0042546,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0071554,GO:0071704,GO:0071766,GO:0071770,GO:0071840,GO:0071944,GO:1901360,GO:1901362,GO:1901576	-	ko:K16167	-	-	-	-	ko00000,ko01008	-	-	-	Chal_sti_synt_C,Chal_sti_synt_N
CMS1_k127_5750016_6	926550.CLDAP_04450	3.019e-14	88.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5750016_4	926550.CLDAP_07830	9.862e-47	195.0	COG4447@1|root,COG4447@2|Bacteria,2G66V@200795|Chloroflexi	200795|Chloroflexi	G	glycosyl hydrolase, BNR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
CMS1_k127_5750016_2	926550.CLDAP_18790	5.378e-79	271.0	COG0175@1|root,COG0175@2|Bacteria,2G8H1@200795|Chloroflexi	200795|Chloroflexi	C	Reduction of activated sulfate into sulfite	cysH	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
CMS1_k127_5750016_5	644966.Tmar_1599	8.507e-15	76.0	COG3682@1|root,COG3682@2|Bacteria,1VGZ0@1239|Firmicutes,24SJ1@186801|Clostridia	186801|Clostridia	K	PFAM Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
CMS1_k127_5751928_0	765420.OSCT_2114	5.689e-292	942.0	COG2931@1|root,COG2931@2|Bacteria,2GBI9@200795|Chloroflexi,377IY@32061|Chloroflexia	32061|Chloroflexia	Q	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
CMS1_k127_5751928_1	269797.Mbar_A2862	1.281e-208	699.0	COG2319@1|root,arCOG02561@2157|Archaea,2Y41K@28890|Euryarchaeota,2NAYQ@224756|Methanomicrobia	224756|Methanomicrobia	S	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	WD40
CMS1_k127_5751928_2	765420.OSCT_3186	1.212e-88	317.0	COG4995@1|root,COG4995@2|Bacteria,2G8YF@200795|Chloroflexi,377C0@32061|Chloroflexia	32061|Chloroflexia	P	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,SIR2_2
CMS1_k127_5771318_0	926560.KE387025_gene3969	1e-323	1000.0	COG2217@1|root,COG2217@2|Bacteria,1WJ55@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	ATPase P-type (Transporting), HAD superfamily, subfamily IC	-	-	-	-	-	-	-	-	-	-	-	-	E1-E2_ATPase,HMA,Hydrolase
CMS1_k127_5771318_2	926560.KE387025_gene3970	2.35e-54	198.0	COG4633@1|root,COG4633@2|Bacteria,1WMVC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Cupredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
CMS1_k127_5771318_6	1122609.AUGT01000022_gene621	1.246e-08	67.0	COG0477@1|root,COG2814@2|Bacteria,2GKHG@201174|Actinobacteria,4DPT4@85009|Propionibacteriales	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
CMS1_k127_5771318_5	187272.Mlg_1384	6.347e-12	68.0	COG3462@1|root,COG3462@2|Bacteria,1NGXC@1224|Proteobacteria,1TKC3@1236|Gammaproteobacteria,1X1RM@135613|Chromatiales	135613|Chromatiales	S	Short C-terminal domain	-	-	-	ko:K08982	-	-	-	-	ko00000	-	-	-	SHOCT
CMS1_k127_5771318_1	926560.KE387025_gene3939	3.062e-168	533.0	COG0057@1|root,COG0057@2|Bacteria	2|Bacteria	G	glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity	-	-	1.2.1.12,1.2.1.59,1.4.1.16	ko:K00134,ko:K00150,ko:K03340	ko00010,ko00300,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00300,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00526,M00552	R01061,R01063,R02755	RC00006,RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	DAPDH_C,DapB_N,Gp_dh_C,Gp_dh_N
CMS1_k127_5771318_7	1111069.TCCBUS3UF1_3820	1.604e-06	55.0	COG0071@1|root,COG0071@2|Bacteria,1WJU3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
CMS1_k127_5771318_4	1142394.PSMK_11260	4.567e-38	150.0	COG0563@1|root,COG0563@2|Bacteria,2IZRF@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK
CMS1_k127_5771318_3	926550.CLDAP_14450	5.23e-45	173.0	COG3815@1|root,COG3815@2|Bacteria	2|Bacteria	S	Predicted membrane protein (DUF2085)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2085
CMS1_k127_5771318_8	555088.DealDRAFT_2162	3.528e-06	56.0	29RA3@1|root,30CBN@2|Bacteria,1W5X6@1239|Firmicutes,25561@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5772226_18	1378168.N510_00844	0.0002544	44.0	COG1476@1|root,COG1476@2|Bacteria,1VMIP@1239|Firmicutes	1239|Firmicutes	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
CMS1_k127_5772226_4	926550.CLDAP_04910	2.965e-116	383.0	COG0837@1|root,COG0837@2|Bacteria,2G7R9@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the bacterial glucokinase family	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucokinase
CMS1_k127_5772226_13	1185766.DL1_07255	6.49e-36	149.0	COG0613@1|root,COG0613@2|Bacteria,1PBDI@1224|Proteobacteria,2U1HY@28211|Alphaproteobacteria,2XN4D@285107|Thioclava	28211|Alphaproteobacteria	S	DNA polymerase alpha chain like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5772226_0	710696.Intca_1127	1.016e-198	658.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,BNR,BNR_2,DUF11,SBBP
CMS1_k127_5772226_2	1123073.KB899245_gene90	3.152e-141	455.0	COG2021@1|root,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,1RQ2N@1236|Gammaproteobacteria,1X88E@135614|Xanthomonadales	135614|Xanthomonadales	E	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CMS1_k127_5772226_8	1121396.KB893051_gene3457	3.31e-88	301.0	COG2267@1|root,COG2267@2|Bacteria,1QVW4@1224|Proteobacteria,42T0R@68525|delta/epsilon subdivisions,2WPP3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
CMS1_k127_5772226_15	697281.Mahau_1207	5.513e-07	51.0	COG2730@1|root,COG2730@2|Bacteria,1V9GI@1239|Firmicutes,24KYA@186801|Clostridia	186801|Clostridia	G	Domain of unknown function (DUF5060)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4038,DUF5060
CMS1_k127_5772226_12	935837.JAEK01000010_gene72	6.741e-56	214.0	COG2182@1|root,COG2182@2|Bacteria,1UI6V@1239|Firmicutes,4ISFX@91061|Bacilli,1ZCIF@1386|Bacillus	91061|Bacilli	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_1,SBP_bac_8
CMS1_k127_5772226_5	697281.Mahau_2566	6.676e-107	355.0	COG1175@1|root,COG1175@2|Bacteria,1TPTZ@1239|Firmicutes,2492R@186801|Clostridia,42FXR@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_5772226_7	697281.Mahau_0771	5.563e-98	327.0	COG0395@1|root,COG0395@2|Bacteria,1TSAB@1239|Firmicutes,25C5T@186801|Clostridia,42JEU@68295|Thermoanaerobacterales	186801|Clostridia	P	COGs COG0395 ABC-type sugar transport system permease component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_5772226_1	1267535.KB906767_gene1629	5.237e-165	560.0	COG3387@1|root,COG3387@2|Bacteria	2|Bacteria	G	glucan 1,4-alpha-glucosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N,F5_F8_type_C,Glyco_hydro_125
CMS1_k127_5772226_10	1267535.KB906767_gene1633	1.538e-82	284.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	araB	-	-	ko:K14274	ko00040,map00040	-	R02427	RC00713	ko00000,ko00001,ko01000	-	-	-	HTH_IclR,IclR,SGL,adh_short
CMS1_k127_5772226_6	926569.ANT_25830	2.087e-104	344.0	COG1028@1|root,COG1028@2|Bacteria,2G6RP@200795|Chloroflexi	200795|Chloroflexi	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS1_k127_5772226_9	1232410.KI421417_gene2719	1.507e-83	284.0	COG1024@1|root,COG1024@2|Bacteria,1Q67Q@1224|Proteobacteria,42SEY@68525|delta/epsilon subdivisions,2WPN4@28221|Deltaproteobacteria,43V21@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS1_k127_5772226_16	886293.Sinac_0914	8.759e-07	59.0	COG2214@1|root,COG2214@2|Bacteria	2|Bacteria	O	Heat shock protein DnaJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
CMS1_k127_5772226_11	221288.JH992901_gene2459	3.506e-82	282.0	COG0454@1|root,COG0456@2|Bacteria,1GD5Y@1117|Cyanobacteria,1JHKK@1189|Stigonemataceae	1117|Cyanobacteria	K	GNAT acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,FR47
CMS1_k127_5772226_14	502025.Hoch_1577	3.421e-23	115.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,1P64D@1224|Proteobacteria,439PY@68525|delta/epsilon subdivisions,2X51T@28221|Deltaproteobacteria,2YZZT@29|Myxococcales	28221|Deltaproteobacteria	KLTU	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS1_k127_5772226_3	926550.CLDAP_19060	5.431e-117	381.0	COG2326@1|root,COG2326@2|Bacteria,2G5UP@200795|Chloroflexi	200795|Chloroflexi	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
CMS1_k127_5772226_17	909663.KI867150_gene786	1.686e-06	51.0	COG0028@1|root,COG0028@2|Bacteria,1MX6Q@1224|Proteobacteria,42T3U@68525|delta/epsilon subdivisions,2WPDH@28221|Deltaproteobacteria,2MRV1@213462|Syntrophobacterales	28221|Deltaproteobacteria	EH	Thiamine pyrophosphate enzyme, central domain	-	-	4.1.1.7	ko:K01576	ko00627,ko01120,map00627,map01120	-	R01764,R02672	RC00595	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS1_k127_5778843_4	1122915.AUGY01000034_gene955	4.781e-15	87.0	COG1653@1|root,COG1653@2|Bacteria,1UZIW@1239|Firmicutes,4HVDN@91061|Bacilli,26SGE@186822|Paenibacillaceae	91061|Bacilli	G	ABC transporter substrate-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_8
CMS1_k127_5778843_1	525904.Tter_0125	1.444e-91	310.0	COG1175@1|root,COG1175@2|Bacteria	2|Bacteria	P	transmembrane transport	-	-	-	ko:K02025,ko:K05814,ko:K10118,ko:K10237,ko:K10241,ko:K15771,ko:K17235,ko:K17316	ko02010,map02010	M00196,M00198,M00204,M00206,M00207,M00491,M00602,M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.17,3.A.1.1.2,3.A.1.1.23,3.A.1.1.24,3.A.1.1.28,3.A.1.1.3,3.A.1.1.30,3.A.1.1.34	-	-	BPD_transp_1
CMS1_k127_5778843_2	525904.Tter_0124	6.68e-80	276.0	COG0395@1|root,COG0395@2|Bacteria	2|Bacteria	P	glycerophosphodiester transmembrane transport	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_5778843_0	1173027.Mic7113_2138	2.7e-96	320.0	28JSX@1|root,2Z9I8@2|Bacteria,1G29W@1117|Cyanobacteria,1H9GC@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function (DUF4058)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4058
CMS1_k127_5783665_6	584708.Apau_1735	7.096e-48	177.0	COG1957@1|root,COG1957@2|Bacteria,3TBMC@508458|Synergistetes	508458|Synergistetes	F	Inosine-uridine preferring nucleoside hydrolase	-	-	3.2.2.8	ko:K10213	ko00230,ko00240,ko01100,map00230,map00240,map01100	-	R01245,R01677,R01770,R02137	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
CMS1_k127_5783665_0	316274.Haur_1060	1.62e-116	384.0	COG2109@1|root,COG3411@1|root,COG2109@2|Bacteria,COG3411@2|Bacteria,2G6Q6@200795|Chloroflexi,375GV@32061|Chloroflexia	32061|Chloroflexia	H	PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP	-	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
CMS1_k127_5783665_8	370438.PTH_1477	5.663e-39	153.0	COG1865@1|root,COG1865@2|Bacteria,1TQHV@1239|Firmicutes,24AA4@186801|Clostridia,262A9@186807|Peptococcaceae	186801|Clostridia	S	Adenosylcobinamide amidohydrolase	cbiZ	-	-	-	-	-	-	-	-	-	-	-	CbiZ
CMS1_k127_5783665_3	765420.OSCT_2409	3.263e-72	255.0	COG1270@1|root,COG1270@2|Bacteria,2G6JG@200795|Chloroflexi,37592@32061|Chloroflexia	32061|Chloroflexia	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	cobD	-	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
CMS1_k127_5783665_1	926550.CLDAP_23850	1.447e-75	267.0	COG0079@1|root,COG1492@1|root,COG0079@2|Bacteria,COG1492@2|Bacteria,2G5PU@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,CbiA,GATase_3
CMS1_k127_5783665_2	1121957.ATVL01000007_gene1734	3.246e-73	254.0	COG0368@1|root,COG0368@2|Bacteria,4NHNT@976|Bacteroidetes,47MF0@768503|Cytophagia	976|Bacteroidetes	H	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate	cobS	-	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CobS
CMS1_k127_5783665_5	926550.CLDAP_13470	6.346e-57	203.0	COG2087@1|root,COG2087@2|Bacteria,2G6SV@200795|Chloroflexi	200795|Chloroflexi	H	PFAM cobalbumin biosynthesis protein	cobU	-	2.7.1.156,2.7.7.62	ko:K02231	ko00860,ko01100,map00860,map01100	M00122	R05221,R05222,R06558	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	CobU
CMS1_k127_5783665_4	292459.STH1933	3.21e-62	222.0	COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,2492Z@186801|Clostridia	186801|Clostridia	HP	Abc transporter	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
CMS1_k127_5783665_7	316274.Haur_1055	3.355e-42	159.0	COG0609@1|root,COG0609@2|Bacteria,2G6E8@200795|Chloroflexi,376D1@32061|Chloroflexia	32061|Chloroflexia	P	FecCD transport family	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
CMS1_k127_5795898_5	1449976.KALB_8465	3.59e-98	336.0	COG5476@1|root,COG5476@2|Bacteria,2GMKS@201174|Actinobacteria,4E8SC@85010|Pseudonocardiales	201174|Actinobacteria	S	MlrC C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	DUF1485,MlrC_C
CMS1_k127_5795898_0	1071679.BG57_05100	4.216e-226	714.0	COG0129@1|root,COG0129@2|Bacteria,1MV4I@1224|Proteobacteria,2VKKY@28216|Betaproteobacteria,1K1H9@119060|Burkholderiaceae	28216|Betaproteobacteria	EG	Belongs to the IlvD Edd family	-	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
CMS1_k127_5795898_1	118163.Ple7327_1947	3.108e-159	510.0	COG4663@1|root,COG4663@2|Bacteria,1G1BA@1117|Cyanobacteria,3VHWR@52604|Pleurocapsales	1117|Cyanobacteria	Q	Part of the tripartite ATP-independent periplasmic (TRAP) transport system	-	GO:0003674,GO:0005215,GO:0005342,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0015849,GO:0022857,GO:0031317,GO:0032991,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043177,GO:0044464,GO:0046872,GO:0046983,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:1903825,GO:1990351	-	-	-	-	-	-	-	-	-	-	DctP
CMS1_k127_5795898_14	926550.CLDAP_39350	6.578e-11	66.0	2BH31@1|root,32B3S@2|Bacteria,2G9T0@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
CMS1_k127_5795898_6	390989.JOEG01000001_gene5303	5.361e-97	327.0	COG0667@1|root,COG0667@2|Bacteria,2GKW7@201174|Actinobacteria,4D98Y@85008|Micromonosporales	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	1.1.1.122	ko:K00064	ko00051,ko00053,ko01100,ko01110,ko01120,map00051,map00053,map01100,map01110,map01120	M00114	R07675,R08926	RC00066,RC00161	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldo_ket_red
CMS1_k127_5795898_13	525904.Tter_2213	3.296e-42	166.0	COG0726@1|root,COG0726@2|Bacteria,2NRJ2@2323|unclassified Bacteria	2|Bacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
CMS1_k127_5795898_7	1227349.C170_23115	4.63e-95	325.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,4HDN8@91061|Bacilli,275I6@186822|Paenibacillaceae	91061|Bacilli	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
CMS1_k127_5795898_12	196490.AUEZ01000002_gene4204	2.288e-53	202.0	COG4948@1|root,COG4948@2|Bacteria,1MW5B@1224|Proteobacteria,2UNXP@28211|Alphaproteobacteria,3K6K3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	gci	-	5.5.1.27	ko:K18983	ko00053,map00053	-	R10847	RC03287	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
CMS1_k127_5795898_9	246197.MXAN_1633	2.834e-75	259.0	COG1670@1|root,COG1670@2|Bacteria,1RKT9@1224|Proteobacteria,42VCK@68525|delta/epsilon subdivisions,2WS7R@28221|Deltaproteobacteria,2Z14V@29|Myxococcales	28221|Deltaproteobacteria	J	Acetyltransferase (GNAT) domain	rimJ2	-	-	ko:K03817	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
CMS1_k127_5795898_4	383372.Rcas_3023	3.09e-108	355.0	COG0684@1|root,COG0684@2|Bacteria,2G8FC@200795|Chloroflexi,377VT@32061|Chloroflexia	32061|Chloroflexia	H	PFAM Dimethylmenaquinone methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
CMS1_k127_5795898_10	411902.CLOBOL_02418	5.912e-70	250.0	COG2017@1|root,COG2017@2|Bacteria,1UEJW@1239|Firmicutes,25JI2@186801|Clostridia,222S6@1506553|Lachnoclostridium	186801|Clostridia	G	Domain of unknown function (DUF4432)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4432
CMS1_k127_5795898_11	1380391.JIAS01000004_gene2970	1.032e-62	225.0	COG3386@1|root,COG3386@2|Bacteria,1RJY7@1224|Proteobacteria	1224|Proteobacteria	G	SMP-30/Gluconolaconase/LRE-like region	-	-	-	-	-	-	-	-	-	-	-	-	SGL
CMS1_k127_5795898_2	525904.Tter_0202	5.014e-110	364.0	COG2141@1|root,COG2141@2|Bacteria	2|Bacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
CMS1_k127_5795898_3	1168289.AJKI01000040_gene3238	4.088e-109	357.0	COG3525@1|root,COG3537@1|root,COG3525@2|Bacteria,COG3537@2|Bacteria,4NE08@976|Bacteroidetes,2FNAR@200643|Bacteroidia,3XJV8@558415|Marinilabiliaceae	976|Bacteroidetes	G	Glycosyl hydrolase family 20, domain 2	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	CHB_HEX_C_1,Fn3_assoc,Glyco_hydro_20,Glyco_hydro_20b,PA14
CMS1_k127_5797576_1	933262.AXAM01000026_gene3097	2.846e-90	302.0	COG1672@1|root,COG1672@2|Bacteria,1R4NN@1224|Proteobacteria,42NMV@68525|delta/epsilon subdivisions,2WM2Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Archaeal ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,AAA_35
CMS1_k127_5797576_5	555779.Dthio_PD3548	1.411e-20	96.0	COG1708@1|root,COG1708@2|Bacteria,1PAUR@1224|Proteobacteria,43377@68525|delta/epsilon subdivisions,2WX93@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5797576_3	102129.Lepto7375DRAFT_2698	1.082e-52	190.0	COG3007@1|root,COG3007@2|Bacteria,1G85A@1117|Cyanobacteria,1HCBR@1150|Oscillatoriales	1117|Cyanobacteria	I	enoyl-[acyl-carrier-protein] reductase (NADH) activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5797576_4	471853.Bcav_4186	1.019e-49	187.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS1_k127_5797576_0	471853.Bcav_4191	7.813e-129	424.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_5797576_2	986075.CathTA2_1055	5.365e-87	293.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,4H9S9@91061|Bacilli	91061|Bacilli	E	Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
CMS1_k127_580437_2	383372.Rcas_3322	1.252e-89	302.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,2G6N4@200795|Chloroflexi,375K6@32061|Chloroflexia	32061|Chloroflexia	K	iron dependent repressor	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
CMS1_k127_580437_7	326427.Cagg_3241	4.961e-19	87.0	COG0267@1|root,COG0267@2|Bacteria,2G9SS@200795|Chloroflexi,377RW@32061|Chloroflexia	32061|Chloroflexia	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
CMS1_k127_580437_8	357808.RoseRS_0880	2.085e-08	59.0	COG2331@1|root,COG2331@2|Bacteria,2G9QZ@200795|Chloroflexi,377TZ@32061|Chloroflexia	32061|Chloroflexia	S	regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
CMS1_k127_580437_5	504728.K649_01800	5.377e-67	231.0	COG0521@1|root,COG0521@2|Bacteria,1WIRM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Molybdenum cofactor biosynthesis protein B	-	-	2.7.7.75	ko:K03638	ko00790,ko01100,map00790,map01100	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
CMS1_k127_580437_3	926550.CLDAP_14490	2.504e-84	284.0	COG0406@1|root,COG0406@2|Bacteria,2G72Q@200795|Chloroflexi	200795|Chloroflexi	G	Phosphoglycerate mutase family	-	-	5.4.2.12	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
CMS1_k127_580437_6	1123373.ATXI01000002_gene637	3.457e-47	181.0	28IGY@1|root,2Z8I9@2|Bacteria,2GHAZ@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_580437_4	1237149.C900_04897	2.466e-71	274.0	COG1672@1|root,COG1672@2|Bacteria,4NN64@976|Bacteroidetes,47UYI@768503|Cytophagia	976|Bacteroidetes	S	PFAM Archaeal ATPase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_580437_1	1121007.AUML01000002_gene1579	1.541e-92	315.0	COG0668@1|root,COG0668@2|Bacteria,4NHU7@976|Bacteroidetes,1I0RF@117743|Flavobacteriia	976|Bacteroidetes	M	Mechanosensitive ion channel	ynaI	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
CMS1_k127_580437_0	526227.Mesil_1427	2.286e-183	581.0	COG0247@1|root,COG0247@2|Bacteria,1WIQB@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	4Fe-4S dicluster domain	glcF	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_7,Fer4_8
CMS1_k127_580437_9	1122222.AXWR01000005_gene612	0.0001682	46.0	COG0277@1|root,COG0277@2|Bacteria,1WJI6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	PFAM FAD linked oxidase domain protein	glcE	-	-	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	FAD_binding_4
CMS1_k127_5805568_1	1121920.AUAU01000012_gene2648	3.417e-96	327.0	COG5557@1|root,COG5557@2|Bacteria,3Y3RF@57723|Acidobacteria	57723|Acidobacteria	C	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
CMS1_k127_5805568_2	439235.Dalk_1855	1.284e-91	309.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42NS2@68525|delta/epsilon subdivisions,2WMA0@28221|Deltaproteobacteria,2MN9Z@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	fdnH	-	-	ko:K00124	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Fer4_11,Fer4_4,NrfD
CMS1_k127_5805568_0	795359.TOPB45_0497	0.0	1037.0	COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,2GGUA@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CMS1_k127_5805568_3	1121413.JMKT01000009_gene2216	2.429e-63	222.0	COG0243@1|root,COG0243@2|Bacteria,1MWPS@1224|Proteobacteria,42QIW@68525|delta/epsilon subdivisions,2WJPY@28221|Deltaproteobacteria,2MB0B@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	molybdopterin oxidoreductase Fe4S4	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,TAT_signal
CMS1_k127_5805568_5	1089553.Tph_c04540	4.214e-10	66.0	COG1918@1|root,COG1918@2|Bacteria,1VMJD@1239|Firmicutes,24VI7@186801|Clostridia,42HGN@68295|Thermoanaerobacterales	186801|Clostridia	P	FeoA	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
CMS1_k127_5805568_4	62928.azo0606	3.413e-26	110.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,2VIRG@28216|Betaproteobacteria,2KVZR@206389|Rhodocyclales	206389|Rhodocyclales	P	transporter of a GTP-driven Fe(2 ) uptake system	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
CMS1_k127_5807567_4	1128421.JAGA01000001_gene2367	9.569e-11	72.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	Beta-lactamase,DUF3471
CMS1_k127_5807567_3	926569.ANT_09860	4.131e-25	111.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	yyaR	-	-	ko:K06889,ko:K19273	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Acetyltransf_1
CMS1_k127_5807567_0	926550.CLDAP_25230	5.835e-134	449.0	COG1595@1|root,COG1595@2|Bacteria,2GBP1@200795|Chloroflexi	200795|Chloroflexi	K	N-terminal 7TM region of histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_7TM
CMS1_k127_5807567_1	1158318.ATXC01000001_gene573	1.841e-84	286.0	COG0217@1|root,COG0217@2|Bacteria,2G3N5@200783|Aquificae	200783|Aquificae	K	transcriptional regulatory protein	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
CMS1_k127_5807567_2	316274.Haur_4753	6.76e-58	205.0	COG0817@1|root,COG0817@2|Bacteria,2G6MA@200795|Chloroflexi,375KP@32061|Chloroflexia	32061|Chloroflexia	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
CMS1_k127_5807567_5	1313172.YM304_19870	0.0004827	43.0	COG0632@1|root,COG0632@2|Bacteria,2GN17@201174|Actinobacteria,4CNA0@84992|Acidimicrobiia	84992|Acidimicrobiia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
CMS1_k127_5809331_0	1128421.JAGA01000003_gene3678	2.849e-194	641.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2NQCZ@2323|unclassified Bacteria	2|Bacteria	K	NB-ARC domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_22,BTAD,NB-ARC,TPR_10,TPR_12,TPR_8,Trans_reg_C
CMS1_k127_5809331_2	316274.Haur_0593	1.508e-26	113.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,2GA6X@200795|Chloroflexi,375DW@32061|Chloroflexia	32061|Chloroflexia	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
CMS1_k127_5809331_1	316274.Haur_1216	1.302e-62	226.0	COG0454@1|root,COG0456@2|Bacteria,2G9FH@200795|Chloroflexi	200795|Chloroflexi	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS1_k127_5825870_7	1121362.A605_04490	2.78e-47	183.0	COG2897@1|root,COG2897@2|Bacteria,2GMDR@201174|Actinobacteria,22MW2@1653|Corynebacteriaceae	201174|Actinobacteria	P	Rhodanese-related sulfurtransferase	sseA2	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
CMS1_k127_5825870_9	1123248.KB893359_gene2063	1.831e-20	98.0	COG5485@1|root,COG5485@2|Bacteria	2|Bacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
CMS1_k127_5825870_1	485913.Krac_2635	2.429e-104	376.0	COG0457@1|root,COG3629@1|root,COG3899@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG3899@2|Bacteria,2G871@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,TPR_12
CMS1_k127_5825870_10	1382306.JNIM01000001_gene3779	4.971e-06	55.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,2G699@200795|Chloroflexi	200795|Chloroflexi	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
CMS1_k127_5825870_12	1121440.AUMA01000009_gene708	0.0001269	48.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL,Lipase_GDSL_2
CMS1_k127_5825870_4	118166.JH976537_gene3690	1.647e-56	212.0	COG3385@1|root,2ZA2Q@2|Bacteria,1G4UP@1117|Cyanobacteria	1117|Cyanobacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
CMS1_k127_5825870_8	477974.Daud_1705	2.221e-25	113.0	COG0250@1|root,COG0250@2|Bacteria	2|Bacteria	K	Participates in transcription elongation, termination and antitermination	nusG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K02601,ko:K05785	-	-	-	-	ko00000,ko03000,ko03009,ko03021	-	-	-	KOW,NusG
CMS1_k127_5825870_5	765420.OSCT_1613	2.894e-56	204.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K10914,ko:K21563	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CMS1_k127_5825870_11	797302.Halru_0017	1.082e-05	53.0	arCOG11887@1|root,arCOG11887@2157|Archaea,2Y0PR@28890|Euryarchaeota,23XTJ@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5825870_0	1128421.JAGA01000002_gene371	1.568e-258	814.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,2NNW5@2323|unclassified Bacteria	2|Bacteria	C	synthetase (ADP forming), alpha	-	-	6.2.1.13	ko:K01905,ko:K09181,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,Acetyltransf_1,CoA_binding_2,Succ_CoA_lig
CMS1_k127_5825870_2	765420.OSCT_1411	6.493e-83	287.0	COG0857@1|root,COG0857@2|Bacteria,2GAB3@200795|Chloroflexi,374UU@32061|Chloroflexia	32061|Chloroflexia	C	PFAM DRTGG domain protein	-	-	-	ko:K06873	-	-	-	-	ko00000	-	-	-	AAA_26,DRTGG
CMS1_k127_5825870_3	1089553.Tph_c06120	2.929e-65	231.0	COG2014@1|root,COG2014@2|Bacteria,1V22I@1239|Firmicutes,24GWQ@186801|Clostridia,42HYX@68295|Thermoanaerobacterales	186801|Clostridia	S	Putative heavy-metal chelation	-	-	-	ko:K09138	-	-	-	-	ko00000	-	-	-	DUF364,DUF4213
CMS1_k127_5825870_6	1288494.EBAPG3_25050	6.114e-56	198.0	COG3588@1|root,COG3588@2|Bacteria,1MVFK@1224|Proteobacteria,2VMRG@28216|Betaproteobacteria,372J6@32003|Nitrosomonadales	28216|Betaproteobacteria	G	Fructose-bisphosphate aldolase class-I	fbaB	-	4.1.2.13	ko:K01623	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000,ko03036,ko04131,ko04147	-	-	-	Glycolytic
CMS1_k127_58272_0	391625.PPSIR1_37129	4.114e-273	848.0	COG0069@1|root,COG4638@1|root,COG0069@2|Bacteria,COG4638@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2WJJR@28221|Deltaproteobacteria,2Z2X8@29|Myxococcales	28221|Deltaproteobacteria	E	Conserved region in glutamate synthase	-	-	2.1.1.21	ko:K22083	ko00680,ko01120,map00680,map01120	-	R01586	RC00554	ko00000,ko00001,ko01000	-	-	-	Fer4,Fer4_10,Fer4_7,Fer4_9,GXGXG,Glu_syn_central,Glu_synthase
CMS1_k127_58272_7	1122179.KB890423_gene2354	8.077e-69	241.0	COG0062@1|root,COG0062@2|Bacteria,4P050@976|Bacteroidetes	976|Bacteroidetes	G	YjeF-related protein N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	YjeF_N
CMS1_k127_58272_4	1173029.JH980292_gene1206	1.726e-79	276.0	COG1028@1|root,COG1028@2|Bacteria,1G7CR@1117|Cyanobacteria,1HFY4@1150|Oscillatoriales	1117|Cyanobacteria	IQ	KR domain	gdh	-	1.1.1.47	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	-	R01520,R01521	RC00066	ko00000,ko00001,ko01000	-	-	-	adh_short,adh_short_C2
CMS1_k127_58272_6	869210.Marky_0686	8.662e-73	252.0	COG3358@1|root,COG3358@2|Bacteria,1WKRG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
CMS1_k127_58272_13	709991.Odosp_2802	5.319e-09	70.0	COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,2FPGA@200643|Bacteroidia,22XI5@171551|Porphyromonadaceae	976|Bacteroidetes	M	Tricorn protease homolog	-	-	-	ko:K08676	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PD40,Peptidase_S41,Tricorn_C1,Tricorn_PDZ
CMS1_k127_58272_2	221288.JH992901_gene3415	2.861e-83	309.0	COG1672@1|root,COG2319@1|root,COG1672@2|Bacteria,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1JJ8I@1189|Stigonemataceae	1117|Cyanobacteria	S	AAA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_35,WD40
CMS1_k127_58272_8	373994.Riv7116_6098	2.301e-68	250.0	COG1672@1|root,COG1672@2|Bacteria,1G0F4@1117|Cyanobacteria,1HMJD@1161|Nostocales	1117|Cyanobacteria	K	K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit	-	-	-	-	-	-	-	-	-	-	-	-	AAA_35,CHAT,TIR_2
CMS1_k127_58272_3	706587.Desti_3753	1.048e-82	286.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,42NUT@68525|delta/epsilon subdivisions,2WKQX@28221|Deltaproteobacteria,2MRX6@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
CMS1_k127_58272_5	1379281.AVAG01000091_gene580	2.564e-74	260.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,42N2V@68525|delta/epsilon subdivisions,2WIPS@28221|Deltaproteobacteria,2M7XX@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	HflC and HflK could regulate a protease	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
CMS1_k127_58272_12	398512.JQKC01000008_gene949	1.089e-34	142.0	COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,25B5Z@186801|Clostridia,3WKSE@541000|Ruminococcaceae	186801|Clostridia	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
CMS1_k127_58272_10	1307761.L21SP2_2777	4.285e-39	160.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	5.99.1.3	ko:K02470,ko:K03833	-	-	-	-	ko00000,ko01000,ko03012,ko03032,ko03400	-	-	-	HATPase_c,HTH_20
CMS1_k127_58272_1	1183438.GKIL_0760	7.498e-85	295.0	COG4398@1|root,COG4398@2|Bacteria,1G0TB@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM FIST C domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
CMS1_k127_58272_11	1296415.JACC01000014_gene1003	8.365e-36	139.0	COG3324@1|root,COG3324@2|Bacteria,4NMFV@976|Bacteroidetes,1I3SY@117743|Flavobacteriia,2YJI3@290174|Aquimarina	976|Bacteroidetes	S	Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
CMS1_k127_58272_9	1121904.ARBP01000010_gene2227	1.033e-54	199.0	2DBQR@1|root,2ZAG2@2|Bacteria,4NK84@976|Bacteroidetes,47NS0@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Collagen_bind_2
CMS1_k127_5827475_12	926550.CLDAP_04470	2.993e-16	83.0	COG1807@1|root,COG1807@2|Bacteria,2G9RZ@200795|Chloroflexi	200795|Chloroflexi	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5827475_4	246194.CHY_1050	1.643e-77	267.0	COG1215@1|root,COG1215@2|Bacteria,1UI5W@1239|Firmicutes,25EJ5@186801|Clostridia,42JFV@68295|Thermoanaerobacterales	186801|Clostridia	M	COGs COG0463 Glycosyltransferase involved in cell wall biogenesis	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
CMS1_k127_5827475_9	1499967.BAYZ01000158_gene458	1.137e-32	147.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_22,PMT_2
CMS1_k127_5827475_11	357808.RoseRS_2507	1.243e-19	103.0	COG5305@1|root,COG5305@2|Bacteria,2G7AA@200795|Chloroflexi,375E4@32061|Chloroflexia	200795|Chloroflexi	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS1_k127_5827475_10	926569.ANT_29310	1.499e-25	117.0	299R9@1|root,2ZWTI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5827475_16	1123319.AUBE01000014_gene5512	2.454e-07	63.0	COG1807@1|root,COG1807@2|Bacteria,2GP96@201174|Actinobacteria	201174|Actinobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS1_k127_5827475_6	1499967.BAYZ01000014_gene6406	1.242e-62	223.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	2.1.1.95	ko:K05928	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00112	R07236,R07504,R10491,R10492	RC00003,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
CMS1_k127_5827475_13	1192034.CAP_6866	1.132e-15	86.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
CMS1_k127_5827475_0	1128427.KB904821_gene205	9.273e-245	770.0	COG0367@1|root,COG0367@2|Bacteria,1G1WZ@1117|Cyanobacteria,1H9W9@1150|Oscillatoriales	1117|Cyanobacteria	E	Asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
CMS1_k127_5827475_17	32057.KB217478_gene4769	0.0002405	44.0	COG3549@1|root,COG3549@2|Bacteria,1G7K5@1117|Cyanobacteria,1HSSA@1161|Nostocales	1117|Cyanobacteria	S	Plasmid maintenance system killer	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5827475_8	575540.Isop_0468	9.668e-45	172.0	COG0500@1|root,COG1215@1|root,COG1215@2|Bacteria,COG2226@2|Bacteria,2J55B@203682|Planctomycetes	203682|Planctomycetes	H	Methylase involved in ubiquinone menaquinone biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS1_k127_5827475_1	926550.CLDAP_10910	3.673e-172	550.0	COG0399@1|root,COG0399@2|Bacteria,2G7Y0@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
CMS1_k127_5827475_5	43989.cce_1281	9.845e-73	252.0	COG1216@1|root,COG1216@2|Bacteria,1GC7H@1117|Cyanobacteria,3KHJE@43988|Cyanothece	1117|Cyanobacteria	S	Glycosyltransferase like family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
CMS1_k127_5827475_2	1382306.JNIM01000001_gene3764	4.471e-162	522.0	COG0277@1|root,COG0277@2|Bacteria,2G8B5@200795|Chloroflexi	200795|Chloroflexi	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_4
CMS1_k127_5827475_3	743299.Acife_3016	7.666e-87	296.0	COG0300@1|root,COG0300@2|Bacteria,1R735@1224|Proteobacteria,1RSHH@1236|Gammaproteobacteria,2ND0R@225057|Acidithiobacillales	225057|Acidithiobacillales	S	short-chain dehydrogenase reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS1_k127_5827475_15	292563.Cyast_0070	1.587e-11	77.0	COG5617@1|root,COG5617@2|Bacteria,1G6H7@1117|Cyanobacteria	1117|Cyanobacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	PTPS_related
CMS1_k127_5832668_0	1385935.N836_03385	3.957e-70	242.0	COG4974@1|root,COG4974@2|Bacteria,1G7AU@1117|Cyanobacteria,1HHKG@1150|Oscillatoriales	1117|Cyanobacteria	L	PFAM Plasmid pRiA4b ORF-3-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3
CMS1_k127_5832668_2	697281.Mahau_1760	2.041e-37	155.0	COG0407@1|root,COG0407@2|Bacteria,1V3M9@1239|Firmicutes,25AY7@186801|Clostridia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
CMS1_k127_5832668_4	479434.Sthe_0124	4.552e-09	68.0	COG0477@1|root,COG2814@2|Bacteria,2G6DM@200795|Chloroflexi,27YS9@189775|Thermomicrobia	189775|Thermomicrobia	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
CMS1_k127_5832668_1	861299.J421_2137	2.741e-68	247.0	COG4733@1|root,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
CMS1_k127_5832668_3	287986.DV20_31495	1.198e-22	99.0	COG1472@1|root,COG1472@2|Bacteria,2GJ5H@201174|Actinobacteria,4DZ5V@85010|Pseudonocardiales	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 3 family	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Glyco_hydro_3,Glyco_hydro_3_C
CMS1_k127_5832731_2	130081.XP_005709279.1	1.362e-33	132.0	COG0152@1|root,KOG2835@2759|Eukaryota	2759|Eukaryota	F	phosphoribosylaminoimidazole carboxylase activity	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009719,GO:0009725,GO:0009733,GO:0009987,GO:0010033,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
CMS1_k127_5832731_0	56110.Oscil6304_0896	3.735e-153	498.0	COG0034@1|root,COG0034@2|Bacteria,1G1C9@1117|Cyanobacteria,1H8KH@1150|Oscillatoriales	1117|Cyanobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
CMS1_k127_5832731_1	109760.SPPG_01143T0	8.722e-124	407.0	COG0151@1|root,KOG0237@2759|Eukaryota,38BPB@33154|Opisthokonta,3NXWQ@4751|Fungi	4751|Fungi	F	bifunctional purine biosynthetic protein	-	GO:0003674,GO:0003824,GO:0004637,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009112,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:1901360,GO:1901564	6.3.3.1,6.3.4.13	ko:K11788	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04208	RC00090,RC00166,RC01100	ko00000,ko00001,ko00002,ko01000	-	-	iMM904.YGL234W,iND750.YGL234W	AIRS,AIRS_C,GARS_A,GARS_C,GARS_N
CMS1_k127_5836476_0	192952.MM_3069	1.102e-278	870.0	COG0474@1|root,arCOG01578@2157|Archaea,2XT4B@28890|Euryarchaeota,2NAFK@224756|Methanomicrobia	224756|Methanomicrobia	P	TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
CMS1_k127_5836476_5	1169143.KB911035_gene2312	8.615e-19	86.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,2VGZV@28216|Betaproteobacteria,1K2IP@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Polyphosphate kinase 2 (PPK2)	-	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
CMS1_k127_5836476_1	1231392.OCGS_2088	7.649e-96	329.0	COG0025@1|root,COG0025@2|Bacteria,1QTUE@1224|Proteobacteria,2TS20@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	COG0025 NhaP-type Na H and K H antiporters	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
CMS1_k127_5836476_3	1123376.AUIU01000011_gene830	5.837e-25	121.0	COG4974@1|root,COG4974@2|Bacteria,3J0KV@40117|Nitrospirae	40117|Nitrospirae	D	Phage integrase, N-terminal SAM-like domain	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
CMS1_k127_5836476_4	289376.THEYE_A0054	2.104e-22	113.0	COG4974@1|root,COG4974@2|Bacteria,3J0KV@40117|Nitrospirae	40117|Nitrospirae	D	Phage integrase, N-terminal SAM-like domain	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
CMS1_k127_5836476_2	485913.Krac_5450	7.387e-34	140.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5,DDE_Tnp_1_4
CMS1_k127_5836476_6	485913.Krac_10336	1.014e-13	78.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5,DDE_Tnp_1_4
CMS1_k127_5838799_1	512565.AMIS_57300	2.31e-75	261.0	COG4221@1|root,COG4221@2|Bacteria,2ICEF@201174|Actinobacteria,4DCJA@85008|Micromonosporales	201174|Actinobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
CMS1_k127_5838799_0	383372.Rcas_2848	1.925e-151	482.0	COG3386@1|root,COG3386@2|Bacteria,2G76H@200795|Chloroflexi	200795|Chloroflexi	G	PFAM SMP-30 Gluconolaconase LRE domain protein	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
CMS1_k127_5838799_2	926569.ANT_29680	1.105e-32	128.0	COG1132@1|root,COG1132@2|Bacteria,2G66A@200795|Chloroflexi	200795|Chloroflexi	V	ABC transporter, transmembrane region	-	-	-	ko:K06147,ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS1_k127_5839725_0	765420.OSCT_1338	6.699e-93	321.0	COG2208@1|root,COG2208@2|Bacteria,2G790@200795|Chloroflexi,3773B@32061|Chloroflexia	32061|Chloroflexia	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
CMS1_k127_5839725_4	485917.Phep_2020	1.034e-25	118.0	COG1657@1|root,COG1657@2|Bacteria	2|Bacteria	I	PFAM Prenyltransferase squalene oxidase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4430,Laminin_G_3,Prenyltrans,SLH,SQHop_cyclase_C
CMS1_k127_5839725_2	517418.Ctha_1973	9.153e-39	151.0	COG1833@1|root,COG1833@2|Bacteria,1FE6Z@1090|Chlorobi	1090|Chlorobi	S	Domain of unknown function DUF123	-	-	-	-	-	-	-	-	-	-	-	-	DUF123
CMS1_k127_5839725_1	926550.CLDAP_32480	2.739e-43	181.0	COG1807@1|root,COG1807@2|Bacteria	926550.CLDAP_32480|-	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5839725_3	1396141.BATP01000006_gene5432	4.892e-34	138.0	COG2312@1|root,COG2885@1|root,COG3209@1|root,COG3210@1|root,COG2312@2|Bacteria,COG2885@2|Bacteria,COG3209@2|Bacteria,COG3210@2|Bacteria,46XSC@74201|Verrucomicrobia,2IWGQ@203494|Verrucomicrobiae	2|Bacteria	M	CotH kinase protein	-	-	-	ko:K02487,ko:K12543	ko02020,map02020	M00330,M00507	-	-	ko00000,ko00001,ko00002,ko02000,ko02022,ko02035,ko02044	1.B.17,3.A.1.109.4	-	-	CotH,Erythro_esteras,LTD,OmpA
CMS1_k127_5842079_21	756067.MicvaDRAFT_4362	1.777e-34	143.0	COG1357@1|root,COG1357@2|Bacteria,1G02C@1117|Cyanobacteria,1H8G5@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
CMS1_k127_5842079_23	2074.JNYD01000008_gene1124	3.042e-05	50.0	COG1708@1|root,COG1708@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	ko:K07076	-	-	-	-	ko00000	-	-	-	NTP_transf_2
CMS1_k127_5842079_10	1118054.CAGW01000015_gene4557	4.605e-85	291.0	COG0726@1|root,COG0726@2|Bacteria,1VA2Q@1239|Firmicutes,4HEX3@91061|Bacilli,2730V@186822|Paenibacillaceae	91061|Bacilli	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
CMS1_k127_5842079_5	357808.RoseRS_3955	4.672e-119	394.0	COG1355@1|root,COG1355@2|Bacteria,2G835@200795|Chloroflexi	200795|Chloroflexi	S	Memo-like protein	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
CMS1_k127_5842079_13	485913.Krac_12126	1.07e-69	241.0	COG0652@1|root,COG0652@2|Bacteria,2G69B@200795|Chloroflexi	200795|Chloroflexi	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
CMS1_k127_5842079_9	926550.CLDAP_35360	1.167e-87	303.0	COG1994@1|root,COG1994@2|Bacteria,2G8E2@200795|Chloroflexi	200795|Chloroflexi	S	PFAM peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
CMS1_k127_5842079_15	926569.ANT_29460	7.336e-56	198.0	COG0757@1|root,COG0757@2|Bacteria,2G70K@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
CMS1_k127_5842079_6	926550.CLDAP_07310	1.241e-112	375.0	COG0337@1|root,COG0703@1|root,COG0337@2|Bacteria,COG0703@2|Bacteria,2G5K8@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
CMS1_k127_5842079_20	243231.GSU2026	4.313e-36	143.0	COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,42WJW@68525|delta/epsilon subdivisions,2WRIA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
CMS1_k127_5842079_1	926550.CLDAP_07330	1.808e-188	597.0	COG0082@1|root,COG0082@2|Bacteria,2G645@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
CMS1_k127_5842079_11	706587.Desti_1326	6.25e-79	273.0	COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,42N54@68525|delta/epsilon subdivisions,2WMGU@28221|Deltaproteobacteria,2MRP9@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
CMS1_k127_5842079_4	289376.THEYE_A1767	3.654e-119	396.0	COG0128@1|root,COG0128@2|Bacteria,3J0BZ@40117|Nitrospirae	40117|Nitrospirae	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
CMS1_k127_5842079_3	868595.Desca_2498	6.788e-144	464.0	COG3535@1|root,COG3535@2|Bacteria,1TR39@1239|Firmicutes,24A65@186801|Clostridia,266Q3@186807|Peptococcaceae	186801|Clostridia	S	Protein of unknown function (DUF917)	-	-	-	ko:K09703	-	-	-	-	ko00000	-	-	-	DUF917
CMS1_k127_5842079_0	1082932.ATCR1_08274	8.429e-204	646.0	COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,2TRBN@28211|Alphaproteobacteria,4BBMU@82115|Rhizobiaceae	28211|Alphaproteobacteria	EQ	N-methylhydantoinase A acetone carboxylase, beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Hydant_A_N,Hydantoinase_A
CMS1_k127_5842079_22	1248760.ANFZ01000012_gene52	3.941e-11	67.0	2EBHU@1|root,335I9@2|Bacteria,1N2MU@1224|Proteobacteria,2UDTV@28211|Alphaproteobacteria,2K746@204457|Sphingomonadales	204457|Sphingomonadales	S	REDY-like protein HapK	-	-	-	-	-	-	-	-	-	-	-	-	HapK
CMS1_k127_5842079_2	2074.JNYD01000057_gene2986	1.123e-166	555.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria,4DZTZ@85010|Pseudonocardiales	201174|Actinobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
CMS1_k127_5842079_17	909663.KI867150_gene1692	1.476e-47	176.0	COG2080@1|root,COG2080@2|Bacteria,1PGQD@1224|Proteobacteria,434AK@68525|delta/epsilon subdivisions,2X9WM@28221|Deltaproteobacteria,2MRQZ@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
CMS1_k127_5842079_16	935840.JAEQ01000019_gene2104	4.449e-55	205.0	COG1319@1|root,COG1319@2|Bacteria,1RCRH@1224|Proteobacteria,2TU08@28211|Alphaproteobacteria,43PT0@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	C	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM	xdhB	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
CMS1_k127_5842079_18	537013.CLOSTMETH_03678	3.091e-41	163.0	COG1028@1|root,COG1028@2|Bacteria,1TZY6@1239|Firmicutes,248QZ@186801|Clostridia,3WIP8@541000|Ruminococcaceae	186801|Clostridia	IQ	Oxidoreductase, short chain dehydrogenase reductase family protein	fabG5	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
CMS1_k127_5842079_14	114615.BRADO4400	5.062e-66	246.0	COG0747@1|root,COG0747@2|Bacteria,1MWR7@1224|Proteobacteria,2TS51@28211|Alphaproteobacteria,3JT3B@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_5842079_7	1120792.JAFV01000001_gene3897	9.107e-101	340.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TQKK@28211|Alphaproteobacteria,36ZQD@31993|Methylocystaceae	28211|Alphaproteobacteria	EP	Binding-protein-dependent transport system inner membrane component	MA20_22705	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_5842079_12	1121033.AUCF01000012_gene938	1.084e-78	274.0	COG1173@1|root,COG1173@2|Bacteria,1MW3R@1224|Proteobacteria,2TUCW@28211|Alphaproteobacteria,2JPAG@204441|Rhodospirillales	204441|Rhodospirillales	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1,OppC_N
CMS1_k127_5842079_8	935836.JAEL01000014_gene2074	6.339e-93	315.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4HA4E@91061|Bacilli,1ZB72@1386|Bacillus	91061|Bacilli	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
CMS1_k127_5842079_19	1227739.Hsw_4241	7.817e-40	158.0	COG1123@1|root,COG4172@2|Bacteria,4NGDP@976|Bacteroidetes,47KUE@768503|Cytophagia	976|Bacteroidetes	P	Belongs to the ABC transporter superfamily	gsiA	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
CMS1_k127_5861255_1	926550.CLDAP_21290	1.828e-101	344.0	COG1541@1|root,COG1541@2|Bacteria,2G695@200795|Chloroflexi	200795|Chloroflexi	H	AMP-binding enzyme	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
CMS1_k127_5861255_0	926550.CLDAP_31570	9.607e-165	524.0	COG0673@1|root,COG0673@2|Bacteria,2G6KB@200795|Chloroflexi	200795|Chloroflexi	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_5861255_3	313606.M23134_07462	8.577e-59	216.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	yqjP	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS1_k127_5861255_2	765420.OSCT_0456	9.62e-61	223.0	COG1893@1|root,COG1893@2|Bacteria,2G718@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
CMS1_k127_5861255_4	429009.Adeg_1223	6.867e-24	106.0	COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,24JA2@186801|Clostridia,42GMG@68295|Thermoanaerobacterales	186801|Clostridia	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
CMS1_k127_5866165_3	1499967.BAYZ01000069_gene1916	2.744e-39	152.0	COG1262@1|root,COG1262@2|Bacteria,2NR8C@2323|unclassified Bacteria	2|Bacteria	S	Sulfatase-modifying factor enzyme 1	-	-	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	FGE-sulfatase,Pkinase
CMS1_k127_5866165_6	489825.LYNGBM3L_73560	7.585e-26	126.0	COG0683@1|root,COG1672@1|root,COG0683@2|Bacteria,COG1672@2|Bacteria,1G4E9@1117|Cyanobacteria,1HAXK@1150|Oscillatoriales	1117|Cyanobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	AAA_16,Peripla_BP_6,TPR_16
CMS1_k127_5866165_5	479434.Sthe_2612	7.542e-26	116.0	COG1920@1|root,COG1920@2|Bacteria,2G76R@200795|Chloroflexi,27YIQ@189775|Thermomicrobia	189775|Thermomicrobia	H	Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor	cofC	-	2.7.7.68	ko:K14941	ko00680,ko01120,map00680,map01120	M00378	R09397	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CofC
CMS1_k127_5866165_0	926550.CLDAP_12760	1.471e-93	316.0	COG0391@1|root,COG0391@2|Bacteria,2G5S2@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM LPPG domain protein containing protein	cofD	-	2.7.8.28	ko:K11212	ko00680,ko01120,map00680,map01120	M00378	R09398	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	UPF0052
CMS1_k127_5866165_2	795666.MW7_3328	1.484e-63	224.0	COG0778@1|root,COG0778@2|Bacteria,1Q9EX@1224|Proteobacteria,2W39R@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CMS1_k127_5866165_1	247634.GPB2148_1800	5.333e-76	262.0	COG1478@1|root,COG1478@2|Bacteria,1PQHN@1224|Proteobacteria,1S12T@1236|Gammaproteobacteria,1J5KY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	F420-0:Gamma-glutamyl ligase	-	-	6.3.2.31,6.3.2.34	ko:K12234	ko00680,ko01120,map00680,map01120	M00378	R09399,R09400	RC00064,RC00090,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_ligase
CMS1_k127_5866165_4	926550.CLDAP_04660	5.679e-26	108.0	COG2085@1|root,COG2085@2|Bacteria,2G7DD@200795|Chloroflexi	200795|Chloroflexi	S	NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
CMS1_k127_588042_2	926569.ANT_19780	8.637e-14	76.0	COG2887@1|root,COG2887@2|Bacteria,2G8SQ@200795|Chloroflexi	200795|Chloroflexi	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
CMS1_k127_588042_1	357808.RoseRS_4187	1.298e-109	363.0	COG1494@1|root,COG1494@2|Bacteria,2G5XR@200795|Chloroflexi,37645@32061|Chloroflexia	32061|Chloroflexia	G	TIGRFAM fructose-1,6-bisphosphatase, class II	-	-	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
CMS1_k127_588042_0	383372.Rcas_0893	4.397e-166	537.0	COG0607@1|root,COG0659@1|root,COG0607@2|Bacteria,COG0659@2|Bacteria,2G83D@200795|Chloroflexi,3764C@32061|Chloroflexia	32061|Chloroflexia	P	Sulfate permease family	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	Rhodanese,STAS,Sulfate_transp
CMS1_k127_5891095_0	306281.AJLK01000081_gene1678	0.0	1626.0	COG0318@1|root,COG1020@1|root,COG0318@2|Bacteria,COG1020@2|Bacteria,1G4CE@1117|Cyanobacteria	1117|Cyanobacteria	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Condensation,PP-binding
CMS1_k127_5896703_8	326427.Cagg_3501	3.9e-33	137.0	COG3850@1|root,COG5002@1|root,COG3850@2|Bacteria,COG5002@2|Bacteria,2G68T@200795|Chloroflexi,3767Z@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	2CSK_N,HAMP,HATPase_c,HisKA
CMS1_k127_5896703_4	383372.Rcas_2599	3.519e-94	313.0	COG0745@1|root,COG0745@2|Bacteria,2G6MM@200795|Chloroflexi,376T7@32061|Chloroflexia	32061|Chloroflexia	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_5896703_11	1158292.JPOE01000002_gene2279	2.295e-11	75.0	COG0675@1|root,COG0675@2|Bacteria,1MUU0@1224|Proteobacteria,2VJG9@28216|Betaproteobacteria,1KN7Z@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Helix-turn-helix domain	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
CMS1_k127_5896703_7	1158345.JNLL01000002_gene2179	9.819e-54	195.0	COG2452@1|root,COG2452@2|Bacteria	2|Bacteria	L	recombinase activity	-	-	-	-	-	-	-	-	-	-	-	-	Resolvase
CMS1_k127_5896703_9	237368.SCABRO_01246	3.088e-30	129.0	COG3415@1|root,COG3415@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_23,HTH_28,HTH_29,HTH_32,HTH_33
CMS1_k127_5896703_5	180332.JTGN01000005_gene2888	1.661e-70	251.0	COG0407@1|root,COG0407@2|Bacteria,1USM0@1239|Firmicutes,248G3@186801|Clostridia	186801|Clostridia	H	Methyltransferase MtaA CmuA family	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,URO-D
CMS1_k127_5896703_10	646529.Desaci_0681	3.917e-30	126.0	COG2020@1|root,COG2020@2|Bacteria,1VKIT@1239|Firmicutes	1239|Firmicutes	O	PFAM Isoprenylcysteine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
CMS1_k127_5896703_0	479434.Sthe_3153	6.781e-139	451.0	COG1108@1|root,COG1108@2|Bacteria,2G7XS@200795|Chloroflexi	200795|Chloroflexi	P	PFAM ABC-3 protein	-	-	-	ko:K11709	ko02010,map02010	M00319	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15	-	-	ABC-3
CMS1_k127_5896703_1	926550.CLDAP_26700	1.432e-124	407.0	COG1108@1|root,COG1108@2|Bacteria,2G5VY@200795|Chloroflexi	200795|Chloroflexi	P	PFAM ABC-3 protein	-	-	-	ko:K11708	ko02010,map02010	M00319	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15	-	-	ABC-3
CMS1_k127_5896703_2	383372.Rcas_1723	1.457e-122	396.0	COG1121@1|root,COG1121@2|Bacteria,2G5WQ@200795|Chloroflexi,374U1@32061|Chloroflexia	32061|Chloroflexia	P	PFAM ABC transporter related	-	-	-	ko:K11710	ko02010,map02010	M00319	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15	-	-	ABC_tran
CMS1_k127_5896703_3	479434.Sthe_3156	1.994e-99	336.0	COG0803@1|root,COG0803@2|Bacteria,2G8F6@200795|Chloroflexi,27XHP@189775|Thermomicrobia	200795|Chloroflexi	P	Belongs to the bacterial solute-binding protein 9 family	-	-	-	ko:K09818,ko:K11707	ko02010,map02010	M00243,M00319	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15	-	-	ZnuA
CMS1_k127_5896703_6	1128421.JAGA01000003_gene3096	5.601e-67	240.0	COG0803@1|root,COG0803@2|Bacteria,2NP5U@2323|unclassified Bacteria	2|Bacteria	P	Zinc-uptake complex component A periplasmic	-	-	-	ko:K02077,ko:K09818	-	M00243,M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ZnuA
CMS1_k127_5897386_4	324602.Caur_3056	5.948e-145	469.0	COG2271@1|root,COG2271@2|Bacteria	2|Bacteria	G	transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_5897386_10	926569.ANT_11650	2.305e-111	372.0	COG1239@1|root,COG1239@2|Bacteria,2G832@200795|Chloroflexi	200795|Chloroflexi	H	SMART AAA ATPase	-	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	Mg_chelatase
CMS1_k127_5897386_8	926550.CLDAP_06710	2.386e-122	405.0	COG0332@1|root,COG0332@2|Bacteria,2G630@200795|Chloroflexi	200795|Chloroflexi	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
CMS1_k127_5897386_3	760568.Desku_2292	5.93e-157	505.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia,2602N@186807|Peptococcaceae	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
CMS1_k127_5897386_11	338963.Pcar_0760	1.862e-104	352.0	COG0585@1|root,COG0585@2|Bacteria,1MXHD@1224|Proteobacteria,42P4E@68525|delta/epsilon subdivisions,2WN09@28221|Deltaproteobacteria,43SVP@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs	truD	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
CMS1_k127_5897386_22	357808.RoseRS_3288	3.236e-35	138.0	COG1366@1|root,COG1366@2|Bacteria,2G9K5@200795|Chloroflexi,375MW@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Sulfate transporter antisigma-factor antagonist STAS	-	-	-	-	-	-	-	-	-	-	-	-	STAS
CMS1_k127_5897386_25	316274.Haur_1623	3.386e-27	117.0	COG2172@1|root,COG2172@2|Bacteria,2GBV4@200795|Chloroflexi,375TN@32061|Chloroflexia	32061|Chloroflexia	T	Histidine kinase-like ATPase domain	-	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
CMS1_k127_5897386_27	926550.CLDAP_22170	2.473e-25	107.0	COG0236@1|root,COG0236@2|Bacteria,2G76M@200795|Chloroflexi	200795|Chloroflexi	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
CMS1_k127_5897386_23	309801.trd_0359	4.389e-34	139.0	COG0746@1|root,COG0746@2|Bacteria,2G786@200795|Chloroflexi,27Y9U@189775|Thermomicrobia	189775|Thermomicrobia	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
CMS1_k127_5897386_19	926569.ANT_04320	4.444e-65	234.0	COG0491@1|root,COG0491@2|Bacteria,2G8XN@200795|Chloroflexi	200795|Chloroflexi	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS1_k127_5897386_14	536227.CcarbDRAFT_0754	1.924e-98	326.0	COG2872@1|root,COG2872@2|Bacteria,1UHS6@1239|Firmicutes,24AK0@186801|Clostridia,36GRN@31979|Clostridiaceae	186801|Clostridia	S	Threonyl alanyl tRNA synthetase SAD	-	-	-	ko:K07050	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA-synt_2c,tRNA_SAD
CMS1_k127_5897386_30	926550.CLDAP_38780	1.712e-13	76.0	COG4249@1|root,COG4249@2|Bacteria,2G8EH@200795|Chloroflexi	200795|Chloroflexi	S	Peptidase C14 caspase catalytic subunit p20	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5897386_1	665571.STHERM_c15920	6.069e-315	995.0	COG0060@1|root,COG0060@2|Bacteria,2J57V@203691|Spirochaetes	203691|Spirochaetes	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
CMS1_k127_5897386_21	1173024.KI912148_gene2693	3.201e-52	188.0	COG0454@1|root,COG0456@2|Bacteria,1G5YW@1117|Cyanobacteria,1JM9F@1189|Stigonemataceae	1117|Cyanobacteria	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS1_k127_5897386_16	485913.Krac_8091	1.765e-80	276.0	COG3393@1|root,COG3393@2|Bacteria,2G8JB@200795|Chloroflexi	200795|Chloroflexi	S	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	FR47
CMS1_k127_5897386_0	479434.Sthe_0337	0.0	1219.0	COG0060@1|root,COG0060@2|Bacteria,2G5SN@200795|Chloroflexi,27XEH@189775|Thermomicrobia	189775|Thermomicrobia	J	Anticodon-binding domain of tRNA	-	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
CMS1_k127_5897386_28	926550.CLDAP_15590	7.477e-25	113.0	2FKQZ@1|root,30TRG@2|Bacteria,2G9KN@200795|Chloroflexi	200795|Chloroflexi	S	Yip1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Yip1
CMS1_k127_5897386_18	926550.CLDAP_37610	1.81e-68	246.0	COG5653@1|root,COG5653@2|Bacteria,2G6Z0@200795|Chloroflexi	200795|Chloroflexi	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
CMS1_k127_5897386_7	316274.Haur_2249	1.965e-130	429.0	COG0438@1|root,COG0438@2|Bacteria,2G5KS@200795|Chloroflexi,374UR@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	2.4.1.250	ko:K15521	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS1_k127_5897386_9	1382356.JQMP01000003_gene2503	7.254e-116	395.0	COG0195@1|root,COG0195@2|Bacteria,2G5M5@200795|Chloroflexi,27XPJ@189775|Thermomicrobia	189775|Thermomicrobia	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
CMS1_k127_5897386_29	1382306.JNIM01000001_gene2753	7.812e-21	94.0	COG2740@1|root,COG2740@2|Bacteria,2G72H@200795|Chloroflexi	200795|Chloroflexi	K	Protein of unknown function (DUF448)	-	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448
CMS1_k127_5897386_2	748727.CLJU_c13150	2.73e-198	634.0	COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,248SJ@186801|Clostridia,36EJE@31979|Clostridiaceae	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
CMS1_k127_5897386_26	621372.ACIH01000015_gene3941	5.383e-27	114.0	COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,4HII1@91061|Bacilli,26YF0@186822|Paenibacillaceae	91061|Bacilli	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
CMS1_k127_5897386_20	1382306.JNIM01000001_gene2748	8.61e-65	232.0	COG0130@1|root,COG0130@2|Bacteria,2G6F4@200795|Chloroflexi	200795|Chloroflexi	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C,TruB_C_2,TruB_N
CMS1_k127_5897386_17	316274.Haur_0245	7.242e-71	250.0	COG0196@1|root,COG0196@2|Bacteria,2G6JF@200795|Chloroflexi,374TG@32061|Chloroflexia	32061|Chloroflexia	H	TIGRFAM riboflavin biosynthesis protein RibF	-	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
CMS1_k127_5897386_31	357808.RoseRS_1951	2.873e-13	79.0	COG0457@1|root,COG0457@2|Bacteria,2G9Z0@200795|Chloroflexi,377FD@32061|Chloroflexia	32061|Chloroflexia	NU	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5897386_15	330214.NIDE0497	2.536e-87	319.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,3J0QY@40117|Nitrospirae	40117|Nitrospirae	G	PEP-utilising enzyme, mobile domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
CMS1_k127_5897386_13	926550.CLDAP_41090	1.583e-98	327.0	COG0745@1|root,COG0745@2|Bacteria,2G5ND@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07667,ko:K07668	ko02020,ko02024,map02020,map02024	M00454,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_5897386_5	765420.OSCT_0214	7.068e-134	444.0	COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,2G66G@200795|Chloroflexi,3754U@32061|Chloroflexia	32061|Chloroflexia	T	SMART PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA,PAS
CMS1_k127_5897386_6	324602.Caur_2872	4.838e-131	428.0	COG1085@1|root,COG1085@2|Bacteria,2G6K5@200795|Chloroflexi,376AM@32061|Chloroflexia	32061|Chloroflexia	H	TIGRFAM galactose-1-phosphate uridylyltransferase	-	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4921,GalP_UDP_tr_C,GalP_UDP_transf
CMS1_k127_5897386_12	326427.Cagg_1592	2.234e-101	340.0	COG0714@1|root,COG0714@2|Bacteria,2G66D@200795|Chloroflexi,374V5@32061|Chloroflexia	32061|Chloroflexia	S	ATPase associated with various cellular activities, AAA_5	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS1_k127_5897386_24	640081.Dsui_1000	2.307e-28	129.0	COG1721@1|root,COG1721@2|Bacteria	2|Bacteria	E	protein (some members contain a von Willebrand factor type A (vWA) domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CMS1_k127_5897386_32	1173022.Cri9333_4253	1.347e-10	73.0	COG1305@1|root,COG1305@2|Bacteria,1FZW2@1117|Cyanobacteria,1H7X1@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Transglutaminase-like superfamily	-	-	2.3.2.13	ko:K22452	-	-	-	-	ko00000,ko01000	-	-	-	DUF3488,DUF4129,Transglut_core
CMS1_k127_5900154_4	309798.COPRO5265_1549	4.425e-21	108.0	COG1653@1|root,COG1653@2|Bacteria,1TQFZ@1239|Firmicutes,249WU@186801|Clostridia,42ENP@68295|Thermoanaerobacterales	186801|Clostridia	G	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K02027,ko:K10236	ko02010,map02010	M00204,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.17	-	-	SBP_bac_1,SBP_bac_8
CMS1_k127_5900154_3	1033810.HLPCO_002949	6.961e-22	96.0	COG2128@1|root,COG2128@2|Bacteria,2NS09@2323|unclassified Bacteria	2|Bacteria	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS1_k127_5900154_5	1033810.HLPCO_002948	1.245e-17	85.0	COG2128@1|root,COG2128@2|Bacteria	2|Bacteria	S	hydroperoxide reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
CMS1_k127_5900154_2	1122132.AQYH01000006_gene3554	7.386e-61	220.0	COG0395@1|root,COG0395@2|Bacteria,1N4I0@1224|Proteobacteria,2TT14@28211|Alphaproteobacteria,4BMAS@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_5900154_1	457412.RSAG_02741	1.66e-63	229.0	COG1175@1|root,COG1175@2|Bacteria,1V0QC@1239|Firmicutes,24DRD@186801|Clostridia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
CMS1_k127_5900154_6	376733.IT41_01480	1.297e-15	90.0	COG1653@1|root,COG1653@2|Bacteria,1MU64@1224|Proteobacteria,2TTUB@28211|Alphaproteobacteria,2PWZB@265|Paracoccus	28211|Alphaproteobacteria	G	Extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_8
CMS1_k127_5900154_7	309807.SRU_0540	3.366e-12	69.0	COG3440@1|root,COG3440@2|Bacteria,4NFST@976|Bacteroidetes	976|Bacteroidetes	L	HNH endonuclease	-	-	-	ko:K07454	-	-	-	-	ko00000	-	-	-	HNH_2
CMS1_k127_5900154_0	1499967.BAYZ01000184_gene4596	3.076e-84	286.0	COG0747@1|root,COG0747@2|Bacteria,2NQSA@2323|unclassified Bacteria	2|Bacteria	E	PFAM extracellular solute-binding protein family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_5910394_0	383372.Rcas_3216	3.453e-145	465.0	COG0667@1|root,COG0667@2|Bacteria,2G6AM@200795|Chloroflexi	200795|Chloroflexi	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS1_k127_5910394_1	926550.CLDAP_00990	2.067e-130	425.0	COG0673@1|root,COG0673@2|Bacteria,2G7R0@200795|Chloroflexi	200795|Chloroflexi	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_5910394_2	357808.RoseRS_3453	1.804e-108	355.0	COG3828@1|root,COG3828@2|Bacteria,2G61G@200795|Chloroflexi	200795|Chloroflexi	S	Trehalose utilisation	-	-	-	ko:K09992	-	-	-	-	ko00000	-	-	-	ThuA
CMS1_k127_5910394_3	485913.Krac_9370	7.22e-94	312.0	COG1132@1|root,COG1132@2|Bacteria,2G86M@200795|Chloroflexi	2|Bacteria	P	COGs COG1132 ABC-type multidrug transport system ATPase and permease components	-	-	-	ko:K06147,ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS1_k127_5915573_0	926550.CLDAP_39030	5.049e-224	730.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2G699@200795|Chloroflexi	200795|Chloroflexi	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Guanylate_cyc,TPR_12
CMS1_k127_5915573_1	97139.C824_02421	3.425e-105	351.0	COG3964@1|root,COG3964@2|Bacteria,1TPXM@1239|Firmicutes,24EFP@186801|Clostridia,36EDQ@31979|Clostridiaceae	186801|Clostridia	S	Amidohydrolase family	-	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
CMS1_k127_5916564_0	926550.CLDAP_30290	5.047e-140	452.0	COG1482@1|root,COG1482@2|Bacteria	2|Bacteria	G	cell wall glycoprotein biosynthetic process	-	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
CMS1_k127_5916564_2	926550.CLDAP_30300	1.179e-56	203.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	manC	-	2.7.7.13,5.3.1.8	ko:K00971,ko:K16011	ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025	M00114,M00361,M00362	R00885,R01819	RC00002,RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	Cupin_2,MannoseP_isomer,NTP_transferase
CMS1_k127_5916564_1	926550.CLDAP_30310	3.119e-68	237.0	COG2140@1|root,COG2140@2|Bacteria	2|Bacteria	G	oxalate decarboxylase activity	pgiA	-	5.3.1.9	ko:K06859	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Cupin_2,GPI
CMS1_k127_5916564_3	1459636.NTE_02728	5.957e-37	155.0	COG0433@1|root,arCOG00280@2157|Archaea	2157|Archaea	I	COG0433 Predicted ATPase	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853,DUF87
CMS1_k127_5944261_1	583355.Caka_2095	1.521e-54	199.0	COG0546@1|root,COG0546@2|Bacteria,46YH3@74201|Verrucomicrobia,3K9K2@414999|Opitutae	414999|Opitutae	S	PFAM Haloacid dehalogenase domain protein hydrolase	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
CMS1_k127_5944261_0	448385.sce5328	1.336e-275	862.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,42N3P@68525|delta/epsilon subdivisions,2WJB7@28221|Deltaproteobacteria,2YWT1@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1259	ILVD_EDD
CMS1_k127_5948446_6	96561.Dole_1695	1.164e-76	269.0	COG1145@1|root,COG1145@2|Bacteria,1MW11@1224|Proteobacteria,42NUY@68525|delta/epsilon subdivisions,2WK01@28221|Deltaproteobacteria,2MMY1@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
CMS1_k127_5948446_4	765420.OSCT_1549	2.339e-180	578.0	COG0154@1|root,COG0154@2|Bacteria,2G7WJ@200795|Chloroflexi,3771Y@32061|Chloroflexia	32061|Chloroflexia	J	Belongs to the amidase family	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
CMS1_k127_5948446_10	675635.Psed_0203	5.213e-14	74.0	2DNVA@1|root,32ZBE@2|Bacteria,2GRAT@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5948446_3	391625.PPSIR1_31263	3.975e-186	612.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1MU0R@1224|Proteobacteria,42NYJ@68525|delta/epsilon subdivisions,2WKYM@28221|Deltaproteobacteria	68525|delta/epsilon subdivisions	GT	Phosphoenolpyruvate synthase	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
CMS1_k127_5948446_7	509191.AEDB02000016_gene22	1.913e-58	214.0	COG2890@1|root,COG2890@2|Bacteria	2|Bacteria	J	protein-(glutamine-N5) methyltransferase activity	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	MethyTransf_Reg,Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
CMS1_k127_5948446_0	913865.DOT_5073	7.018e-295	925.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1UIEA@1239|Firmicutes,25EJM@186801|Clostridia,2642N@186807|Peptococcaceae	186801|Clostridia	GT	Pyruvate phosphate dikinase, PEP pyruvate binding	ppdK	-	2.7.9.1,2.7.9.2	ko:K01006,ko:K01007	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173,M00374	R00199,R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
CMS1_k127_5948446_2	1449044.JMLE01000002_gene4297	8.509e-238	763.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2GMN4@201174|Actinobacteria,1W9JV@1268|Micrococcaceae	201174|Actinobacteria	G	pyruvate phosphate dikinase, PEP	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
CMS1_k127_5948446_5	406124.ACPC01000043_gene1820	1.508e-106	359.0	COG0477@1|root,COG2814@2|Bacteria,1TS6K@1239|Firmicutes,4HB1V@91061|Bacilli,1ZB90@1386|Bacillus	91061|Bacilli	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	ko:K08153	-	M00717	-	-	ko00000,ko00002,ko02000	2.A.1.2.8	-	-	MFS_1,Sugar_tr
CMS1_k127_5948446_1	42256.RradSPS_0358	1.309e-244	786.0	COG2909@1|root,COG2909@2|Bacteria,2HENR@201174|Actinobacteria,4CPC9@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,AAA_22,GerE
CMS1_k127_5948446_9	675635.Psed_0203	1.208e-14	78.0	2DNVA@1|root,32ZBE@2|Bacteria,2GRAT@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5948446_11	926569.ANT_13140	0.0006531	44.0	COG1595@1|root,COG1595@2|Bacteria,2G6T5@200795|Chloroflexi	200795|Chloroflexi	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_5963785_8	658086.HMPREF0994_01161	1.028e-50	187.0	COG1215@1|root,COG1215@2|Bacteria,1TPBB@1239|Firmicutes,24A20@186801|Clostridia,27IMV@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS1_k127_5963785_7	760568.Desku_1322	1.251e-60	233.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,26066@186807|Peptococcaceae	186801|Clostridia	KLT	PFAM Protein kinase domain	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
CMS1_k127_5963785_0	383372.Rcas_1852	1.01e-168	543.0	COG0364@1|root,COG0364@2|Bacteria,2G5MB@200795|Chloroflexi,374UD@32061|Chloroflexia	32061|Chloroflexia	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
CMS1_k127_5963785_5	926569.ANT_28000	1.211e-69	255.0	COG2203@1|root,COG2204@1|root,COG5002@1|root,COG2203@2|Bacteria,COG2204@2|Bacteria,COG5002@2|Bacteria,2GBJN@200795|Chloroflexi	200795|Chloroflexi	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,Response_reg
CMS1_k127_5963785_1	926550.CLDAP_12040	3.265e-154	497.0	COG0536@1|root,COG0536@2|Bacteria,2G5ZT@200795|Chloroflexi	200795|Chloroflexi	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
CMS1_k127_5963785_9	1382356.JQMP01000003_gene2167	3.553e-49	183.0	COG1057@1|root,COG1057@2|Bacteria,2G6MY@200795|Chloroflexi,27Y96@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
CMS1_k127_5963785_4	926550.CLDAP_21260	2.02e-92	308.0	COG0605@1|root,COG0605@2|Bacteria,2G5Q9@200795|Chloroflexi	200795|Chloroflexi	C	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sod	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
CMS1_k127_5963785_10	926550.CLDAP_18190	1.381e-46	170.0	COG1146@1|root,COG1146@2|Bacteria,2G75G@200795|Chloroflexi	200795|Chloroflexi	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4
CMS1_k127_5963785_6	309801.trd_0489	5.224e-62	221.0	COG2120@1|root,COG2120@2|Bacteria,2G6FB@200795|Chloroflexi,27XM3@189775|Thermomicrobia	189775|Thermomicrobia	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
CMS1_k127_5963785_3	1521187.JPIM01000035_gene3399	1.158e-103	344.0	COG0173@1|root,COG0173@2|Bacteria,2G5RX@200795|Chloroflexi,374WK@32061|Chloroflexia	32061|Chloroflexia	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
CMS1_k127_5964082_1	469383.Cwoe_1673	5.474e-20	92.0	COG0465@1|root,COG0465@2|Bacteria,2GJ4Q@201174|Actinobacteria,4CPFJ@84995|Rubrobacteria	84995|Rubrobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	-	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
CMS1_k127_5964082_0	103733.JNYO01000017_gene3187	5.509e-23	117.0	2F121@1|root,33TFM@2|Bacteria,2I3IA@201174|Actinobacteria,4E5QA@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5985821_7	1384049.CD29_10590	1.276e-10	64.0	COG0501@1|root,COG0501@2|Bacteria,1TRQE@1239|Firmicutes,4HD5G@91061|Bacilli,3IXBG@400634|Lysinibacillus	91061|Bacilli	O	Peptidase M48	yhfN	GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0070011,GO:0071586,GO:0071704,GO:0080120,GO:0140096,GO:1901564	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,Peptidase_M48_N
CMS1_k127_5985821_2	383372.Rcas_2455	5.962e-167	530.0	COG4608@1|root,COG4608@2|Bacteria,2G5R5@200795|Chloroflexi,3754I@32061|Chloroflexia	200795|Chloroflexi	P	TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
CMS1_k127_5985821_5	911045.PSE_2045	6.171e-127	432.0	COG0747@1|root,COG0747@2|Bacteria,1MU3P@1224|Proteobacteria,2TT4M@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	ABC-type dipeptide transport system periplasmic component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_5985821_6	383372.Rcas_2453	6.271e-127	414.0	COG0601@1|root,COG0601@2|Bacteria,2G7WN@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_5985821_3	383372.Rcas_2452	1.617e-142	463.0	COG1173@1|root,COG1173@2|Bacteria,2G7U9@200795|Chloroflexi,377XX@32061|Chloroflexia	32061|Chloroflexia	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
CMS1_k127_5985821_4	383372.Rcas_2451	4.414e-135	444.0	COG0444@1|root,COG0444@2|Bacteria,2G893@200795|Chloroflexi	200795|Chloroflexi	P	TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
CMS1_k127_5985821_1	383372.Rcas_2446	2.767e-188	617.0	2CC7E@1|root,2Z7WG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5985821_0	926550.CLDAP_12700	1.293e-191	617.0	COG0326@1|root,COG0326@2|Bacteria,2G60B@200795|Chloroflexi	200795|Chloroflexi	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
CMS1_k127_6010733_1	1122919.KB905617_gene161	2.178e-105	349.0	COG3119@1|root,COG3119@2|Bacteria,1UDRD@1239|Firmicutes,4HD9J@91061|Bacilli,26WKF@186822|Paenibacillaceae	91061|Bacilli	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CMS1_k127_6010733_5	653045.Strvi_4235	1.248e-36	147.0	COG1082@1|root,COG1082@2|Bacteria,2IHEN@201174|Actinobacteria	201174|Actinobacteria	G	Xylose isomerase-like TIM barrel	-	-	4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
CMS1_k127_6010733_2	485913.Krac_4710	2.354e-104	354.0	COG0477@1|root,COG2814@2|Bacteria,2G7RU@200795|Chloroflexi	200795|Chloroflexi	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
CMS1_k127_6010733_6	313628.LNTAR_19075	7.222e-21	102.0	COG1349@1|root,COG1349@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	3.6.4.12	ko:K02444,ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	AlbA_2,DUF1670,DeoRC,HATPase_c_4,HTH_DeoR
CMS1_k127_6010733_3	765420.OSCT_1145	9.04e-61	226.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_6010733_4	357804.Ping_3145	2.335e-59	214.0	COG0494@1|root,COG0494@2|Bacteria,1RHH9@1224|Proteobacteria,1S8DK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS1_k127_6010733_0	697281.Mahau_2031	4.49e-133	429.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia,42I0Z@68295|Thermoanaerobacterales	186801|Clostridia	G	Fibronectin type III-like domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
CMS1_k127_6023550_4	443255.SCLAV_2188	3.44e-20	93.0	COG4043@1|root,COG4043@2|Bacteria,2IMD7@201174|Actinobacteria	201174|Actinobacteria	S	ASCH	-	-	-	-	-	-	-	-	-	-	-	-	ASCH
CMS1_k127_6023550_3	1449063.JMLS01000005_gene3300	1.619e-106	349.0	29765@1|root,2ZUE2@2|Bacteria,1V4EN@1239|Firmicutes,4HU3Q@91061|Bacilli,275E7@186822|Paenibacillaceae	91061|Bacilli	S	Domain of unknown function (DUF1961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1961
CMS1_k127_6023550_5	113355.CM001775_gene441	3.612e-13	81.0	COG0823@1|root,COG1215@1|root,COG0823@2|Bacteria,COG1215@2|Bacteria,1GCQS@1117|Cyanobacteria	1117|Cyanobacteria	U	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_6023550_6	880070.Cycma_3900	2.337e-07	63.0	COG0823@1|root,COG0823@2|Bacteria,4NQ0C@976|Bacteroidetes,47PP7@768503|Cytophagia	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_6023550_1	1449063.JMLS01000007_gene3385	5.691e-199	630.0	COG3119@1|root,COG3119@2|Bacteria,1W717@1239|Firmicutes,4IACN@91061|Bacilli,272NH@186822|Paenibacillaceae	91061|Bacilli	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS1_k127_6023550_0	383372.Rcas_2454	3.236e-248	783.0	COG0747@1|root,COG0747@2|Bacteria,2G84E@200795|Chloroflexi	200795|Chloroflexi	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_6023550_2	1128421.JAGA01000001_gene2100	6.149e-161	513.0	COG0673@1|root,COG0673@2|Bacteria,2NR0C@2323|unclassified Bacteria	2|Bacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_6034494_8	926569.ANT_20880	3.215e-45	173.0	COG1011@1|root,COG1011@2|Bacteria,2G74Q@200795|Chloroflexi	200795|Chloroflexi	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
CMS1_k127_6034494_3	926550.CLDAP_34420	1.913e-97	337.0	COG1253@1|root,COG1253@2|Bacteria,2G6DE@200795|Chloroflexi	200795|Chloroflexi	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
CMS1_k127_6034494_2	1121382.JQKG01000016_gene1585	8.237e-105	355.0	COG1253@1|root,COG1253@2|Bacteria,1WI7Q@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	COGs COG1253 Hemolysins and related protein containing CBS domains	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
CMS1_k127_6034494_9	926550.CLDAP_23770	1.554e-43	176.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
CMS1_k127_6034494_6	926550.CLDAP_04380	9.261e-51	193.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,2G6Q7@200795|Chloroflexi	200795|Chloroflexi	M	Peptidoglycan-binding LysM	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23,SH3_3
CMS1_k127_6034494_7	926550.CLDAP_23360	1.67e-46	176.0	COG0745@1|root,COG1716@1|root,COG0745@2|Bacteria,COG1716@2|Bacteria,2G8QX@200795|Chloroflexi	200795|Chloroflexi	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
CMS1_k127_6034494_4	926569.ANT_13330	9.138e-93	315.0	COG0515@1|root,COG0515@2|Bacteria,2G850@200795|Chloroflexi	200795|Chloroflexi	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
CMS1_k127_6034494_0	485913.Krac_4320	1e-317	981.0	COG3962@1|root,COG3962@2|Bacteria,2G68S@200795|Chloroflexi	200795|Chloroflexi	E	Thiamine pyrophosphate enzyme, central domain	-	-	3.7.1.22	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R08603	RC02331	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS1_k127_6034494_1	926550.CLDAP_26030	1.425e-130	426.0	COG1082@1|root,COG1082@2|Bacteria,2G613@200795|Chloroflexi	200795|Chloroflexi	G	Xylose isomerase-like TIM barrel	-	-	4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
CMS1_k127_6034494_5	552811.Dehly_1218	1.264e-71	254.0	COG3684@1|root,COG3684@2|Bacteria,2G5XK@200795|Chloroflexi,34CKX@301297|Dehalococcoidia	301297|Dehalococcoidia	G	DeoC/LacD family aldolase	-	-	4.1.2.40	ko:K01635	ko00052,ko01100,ko02024,map00052,map01100,map02024	-	R01069	RC00438,RC00439	ko00000,ko00001,ko01000	-	-	-	DeoC
CMS1_k127_6034494_10	525904.Tter_2038	3.7e-38	147.0	COG2407@1|root,COG2407@2|Bacteria,2NR9P@2323|unclassified Bacteria	2|Bacteria	G	Catalyzes the conversion of L-arabinose to L-ribulose	-	-	5.3.1.4	ko:K01804	ko00040,ko01100,map00040,map01100	-	R01761	RC00516	ko00000,ko00001,ko01000	-	-	-	Arabinose_Isome,Fucose_iso_C
CMS1_k127_6039981_2	448385.sce1233	2.838e-34	143.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,42Q71@68525|delta/epsilon subdivisions,2WK8Q@28221|Deltaproteobacteria,2YTXS@29|Myxococcales	28221|Deltaproteobacteria	F	5'-nucleotidase, C-terminal domain	-	-	3.1.3.5,3.6.1.45	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C
CMS1_k127_6039981_1	1235792.C808_01392	5.852e-83	292.0	COG4690@1|root,COG4690@2|Bacteria,1V44V@1239|Firmicutes	1239|Firmicutes	E	Peptidase family C69	-	-	-	ko:K14358	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C69
CMS1_k127_6039981_0	697281.Mahau_1531	1.016e-91	314.0	COG0412@1|root,COG0412@2|Bacteria,1TQQS@1239|Firmicutes,24DCW@186801|Clostridia,42FHF@68295|Thermoanaerobacterales	186801|Clostridia	Q	Abhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_7,BAAT_C
CMS1_k127_6039981_3	1089551.KE386572_gene314	1.657e-15	81.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,2TRRH@28211|Alphaproteobacteria,4BPR6@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
CMS1_k127_606891_3	1121011.AUCB01000035_gene855	2.62e-117	385.0	COG1524@1|root,COG1524@2|Bacteria,4NIX9@976|Bacteroidetes,1I94B@117743|Flavobacteriia,23I38@178469|Arenibacter	976|Bacteroidetes	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	3.11.1.2	ko:K19670	ko00440,map00440	-	R00318	RC01309	ko00000,ko00001,ko01000	-	-	-	Phosphodiest
CMS1_k127_606891_4	1499967.BAYZ01000095_gene4153	6.103e-111	370.0	COG0738@1|root,COG0738@2|Bacteria,2NQUK@2323|unclassified Bacteria	2|Bacteria	G	Major Facilitator Superfamily	araJ1	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_606891_5	485913.Krac_5030	3.773e-84	288.0	COG2514@1|root,COG2514@2|Bacteria,2G6MQ@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	1.13.11.2	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	M00569	R00816,R04089,R05295,R05404,R05406,R07795	RC00387,RC00643,RC01075,RC01364,RC01914	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
CMS1_k127_606891_0	926550.CLDAP_05480	1.964e-156	501.0	COG3386@1|root,COG3386@2|Bacteria,2G76H@200795|Chloroflexi	200795|Chloroflexi	G	PFAM SMP-30 Gluconolaconase LRE domain protein	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
CMS1_k127_606891_7	1280390.CBQR020000102_gene2713	2.075e-39	159.0	COG3001@1|root,COG3001@2|Bacteria,1VRW7@1239|Firmicutes,4HV5D@91061|Bacilli,271W4@186822|Paenibacillaceae	91061|Bacilli	G	Fructosamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS1_k127_606891_1	570967.JMLV01000015_gene3094	3.784e-149	482.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,2TTYC@28211|Alphaproteobacteria,2JPTH@204441|Rhodospirillales	204441|Rhodospirillales	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
CMS1_k127_606891_2	861299.J421_1476	1.453e-135	438.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	-	-	4.1.1.45	ko:K03392	ko00380,ko01100,map00380,map01100	M00038	R04323	RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
CMS1_k127_606891_6	324602.Caur_0584	6.363e-84	316.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	cpeY	-	-	ko:K05385	ko00196,ko01100,map00196,map01100	-	-	-	ko00000,ko00001,ko00194	-	-	-	CHAT,DUF1822,HEAT_2,Lipase_GDSL_2,Vitellogenin_N
CMS1_k127_606891_8	1033743.CAES01000046_gene267	1.394e-27	118.0	COG0520@1|root,COG0520@2|Bacteria,1UNKQ@1239|Firmicutes,4HTGN@91061|Bacilli	91061|Bacilli	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
CMS1_k127_6069435_3	485913.Krac_4777	5.973e-15	79.0	COG2909@1|root,COG2909@2|Bacteria	2|Bacteria	K	trisaccharide binding	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
CMS1_k127_6069435_7	935948.KE386495_gene1080	1.5e-05	58.0	2BZHQ@1|root,33XJQ@2|Bacteria,1VVE3@1239|Firmicutes,250NM@186801|Clostridia,42IBT@68295|Thermoanaerobacterales	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_6069435_6	1047013.AQSP01000122_gene2228	8.224e-07	59.0	294GU@1|root,2ZRWK@2|Bacteria,2NRXQ@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_6069435_0	1047013.AQSP01000122_gene2229	1.573e-243	766.0	COG2192@1|root,COG2192@2|Bacteria,2NNRR@2323|unclassified Bacteria	2|Bacteria	O	Carbamoyltransferase C-terminus	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
CMS1_k127_6069435_2	1499967.BAYZ01000105_gene3517	4.621e-27	124.0	COG2755@1|root,COG2755@2|Bacteria,2NR42@2323|unclassified Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	ChitinaseA_N,Lipase_GDSL_2
CMS1_k127_6069435_1	1499967.BAYZ01000030_gene1167	6.379e-36	151.0	COG1520@1|root,COG1572@1|root,COG3210@1|root,COG1520@2|Bacteria,COG1572@2|Bacteria,COG3210@2|Bacteria,2NRGG@2323|unclassified Bacteria	2|Bacteria	U	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	1.1.2.6	ko:K05889,ko:K12678	-	-	R03136	-	ko00000,ko01000,ko02000,ko02044	1.B.12.1.1,1.B.12.1.3	-	-	CARDB,Cadherin-like,Calx-beta,Chlam_PMP,Flg_new,Lectin_legB,PQQ_2,SLH
CMS1_k127_6074921_1	525904.Tter_0583	1.274e-27	123.0	2AZDP@1|root,31RMA@2|Bacteria,2NRKB@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function (DUF4230)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4230
CMS1_k127_6074921_0	1128421.JAGA01000003_gene2995	3.278e-304	959.0	COG0013@1|root,COG0013@2|Bacteria,2NNYC@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0001130,GO:0001131,GO:0001141,GO:0001217,GO:0002161,GO:0002196,GO:0003674,GO:0003700,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006355,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009451,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019219,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:0140110,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iECABU_c1320.ECABU_c29670,iECED1_1282.ECED1_3146,iEcHS_1320.EcHS_A2833,iJN746.PP_4474	DHHA1,tRNA-synt_2c,tRNA_SAD
CMS1_k127_6074921_3	983917.RGE_09580	0.0008566	51.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,2VGZP@28216|Betaproteobacteria,1KJVQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
CMS1_k127_6103923_25	319795.Dgeo_2207	9.87e-06	48.0	COG2166@1|root,COG2166@2|Bacteria,1WK00@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	SufE protein probably involved in Fe-S center assembly	sufE	-	-	ko:K02426	-	-	-	-	ko00000	-	-	-	SufE
CMS1_k127_6103923_9	316274.Haur_0593	1.076e-58	222.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,2GA6X@200795|Chloroflexi,375DW@32061|Chloroflexia	32061|Chloroflexia	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
CMS1_k127_6103923_8	765420.OSCT_0969	2.766e-60	218.0	COG2264@1|root,COG2264@2|Bacteria,2G69X@200795|Chloroflexi,374X2@32061|Chloroflexia	32061|Chloroflexia	J	Methylates ribosomal protein L11	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
CMS1_k127_6103923_20	1038859.AXAU01000002_gene767	1.656e-34	146.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Cu-oxidase_3,Cupredoxin_1
CMS1_k127_6103923_24	479434.Sthe_3198	1.308e-10	72.0	COG5662@1|root,COG5662@2|Bacteria,2G96Y@200795|Chloroflexi,27YEM@189775|Thermomicrobia	189775|Thermomicrobia	K	Anti-sigma-K factor rskA	-	-	-	-	-	-	-	-	-	-	-	-	RskA,zf-HC2
CMS1_k127_6103923_19	1382356.JQMP01000004_gene183	7.82e-36	146.0	COG1595@1|root,COG1595@2|Bacteria,2G6UE@200795|Chloroflexi,27YAV@189775|Thermomicrobia	189775|Thermomicrobia	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_6103923_13	926550.CLDAP_10960	2.12e-46	172.0	COG2030@1|root,COG2030@2|Bacteria,2G966@200795|Chloroflexi	200795|Chloroflexi	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
CMS1_k127_6103923_15	324602.Caur_2667	1.819e-42	165.0	COG0170@1|root,COG0170@2|Bacteria,2GBR5@200795|Chloroflexi,3767Q@32061|Chloroflexia	32061|Chloroflexia	M	PFAM phosphatidate cytidylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_6103923_6	316274.Haur_3467	1.111e-71	252.0	COG0524@1|root,COG0524@2|Bacteria,2G8C3@200795|Chloroflexi,376T5@32061|Chloroflexia	32061|Chloroflexia	H	PFAM PfkB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
CMS1_k127_6103923_2	926550.CLDAP_02560	1.904e-179	570.0	COG0172@1|root,COG0172@2|Bacteria,2G5PD@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
CMS1_k127_6103923_7	926550.CLDAP_03610	3.825e-62	220.0	COG0424@1|root,COG0424@2|Bacteria,2G6U2@200795|Chloroflexi	200795|Chloroflexi	D	PFAM Maf family protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
CMS1_k127_6103923_5	324602.Caur_2094	3.388e-73	261.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,2GA6X@200795|Chloroflexi,375DW@32061|Chloroflexia	32061|Chloroflexia	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
CMS1_k127_6103923_1	926569.ANT_11770	1.536e-179	578.0	COG0498@1|root,COG0784@1|root,COG0498@2|Bacteria,COG0784@2|Bacteria,2G5RK@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS1_k127_6103923_3	926569.ANT_11780	2.01e-147	526.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG2203@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,2G84W@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
CMS1_k127_6103923_16	926569.ANT_11800	1.264e-39	172.0	COG2203@1|root,COG3850@1|root,COG2203@2|Bacteria,COG3850@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	2.7.13.3	ko:K07638,ko:K07673,ko:K21009	ko02020,ko02025,ko02026,map02020,map02025,map02026	M00445,M00471,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	AAA_16,GAF,GAF_2,GGDEF,HAMP,HATPase_c,HD,HisKA,PAS_3,PAS_9,PilJ,Pkinase,Response_reg,SpoIIE
CMS1_k127_6103923_23	211586.SO_0859	7.139e-15	90.0	COG0745@1|root,COG0784@1|root,COG2198@1|root,COG2202@1|root,COG3852@1|root,COG4251@1|root,COG5000@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2202@2|Bacteria,COG3852@2|Bacteria,COG4251@2|Bacteria,COG5000@2|Bacteria,1NC9X@1224|Proteobacteria,1SVEC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_9,Response_reg
CMS1_k127_6103923_14	926569.ANT_11820	4.256e-43	183.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF,HATPase_c,HisKA,SpoIIE
CMS1_k127_6103923_12	926569.ANT_11840	1.844e-48	177.0	COG0784@1|root,COG0784@2|Bacteria,2G9B3@200795|Chloroflexi	200795|Chloroflexi	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS1_k127_6103923_18	926569.ANT_11850	3.716e-37	143.0	COG0784@1|root,COG0784@2|Bacteria,2GBNB@200795|Chloroflexi	200795|Chloroflexi	T	cheY-homologous receiver domain	-	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
CMS1_k127_6103923_22	398767.Glov_2786	5.932e-17	85.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,43U5W@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	response regulator	gnfM	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS1_k127_6103923_17	1128421.JAGA01000001_gene2388	2.825e-39	156.0	COG0745@1|root,COG0745@2|Bacteria	1128421.JAGA01000001_gene2388|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_6103923_11	1121441.AUCX01000010_gene104	4.96e-52	206.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,42MC9@68525|delta/epsilon subdivisions,2WIYS@28221|Deltaproteobacteria,2M8UQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	2.7.13.3	ko:K07709	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,sCache_3_2
CMS1_k127_6103923_21	667014.Thein_1130	1.596e-24	120.0	COG2204@1|root,COG2204@2|Bacteria,2GGZ6@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	T	AAA domain (Cdc48 subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS1_k127_6103923_10	1163617.SCD_n02293	1.668e-56	222.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VJGE@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
CMS1_k127_6103923_4	383372.Rcas_1744	9.707e-131	432.0	COG1349@1|root,COG2865@1|root,COG1349@2|Bacteria,COG2865@2|Bacteria,2G7JP@200795|Chloroflexi,374XQ@32061|Chloroflexia	32061|Chloroflexia	K	PFAM AAA-4 family protein	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,HATPase_c_4,HTH_DeoR
CMS1_k127_6103923_0	748449.Halha_2025	4.232e-235	751.0	COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,247SH@186801|Clostridia,3WA90@53433|Halanaerobiales	186801|Clostridia	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
CMS1_k127_6111479_3	1123274.KB899406_gene1124	2.682e-61	228.0	COG2202@1|root,COG2203@1|root,COG2208@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	FHA,GAF,GAF_2,PAS_3,PAS_9,SSF,SpoIIE
CMS1_k127_6111479_8	1173028.ANKO01000130_gene1885	7.934e-13	72.0	COG1366@1|root,COG1366@2|Bacteria,1G7NW@1117|Cyanobacteria,1HCQQ@1150|Oscillatoriales	1117|Cyanobacteria	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	-	-	-	-	-	-	-	-	-	STAS
CMS1_k127_6111479_7	317619.ANKN01000060_gene2718	9.364e-16	81.0	COG1366@1|root,COG1366@2|Bacteria,1G5PW@1117|Cyanobacteria	1117|Cyanobacteria	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
CMS1_k127_6111479_6	1122201.AUAZ01000001_gene2422	7.793e-24	105.0	COG0745@1|root,COG0745@2|Bacteria,1RHCU@1224|Proteobacteria,1SBB6@1236|Gammaproteobacteria,46B2G@72275|Alteromonadaceae	1236|Gammaproteobacteria	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
CMS1_k127_6111479_5	383372.Rcas_2149	2.161e-47	183.0	COG0265@1|root,COG0265@2|Bacteria,2G6KV@200795|Chloroflexi,375DX@32061|Chloroflexia	32061|Chloroflexia	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	1.3.1.74	ko:K08070	-	-	-	-	ko00000,ko01000	-	-	-	PDZ_2,Trypsin_2
CMS1_k127_6111479_1	926569.ANT_09430	5.194e-116	382.0	COG0709@1|root,COG0709@2|Bacteria,2G5W4@200795|Chloroflexi	200795|Chloroflexi	H	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
CMS1_k127_6111479_0	1198232.CYCME_0501	1.968e-117	389.0	COG3568@1|root,COG3568@2|Bacteria,1RJX3@1224|Proteobacteria,1S7J9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CMS1_k127_6111479_2	926569.ANT_23660	1.339e-81	283.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
CMS1_k127_6111479_4	586416.GZ22_02435	4.064e-54	198.0	COG2074@1|root,COG2074@2|Bacteria,1VBU6@1239|Firmicutes,4HMME@91061|Bacilli	91061|Bacilli	G	An automated process has identified a potential problem with this gene model	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_6155978_4	383372.Rcas_0516	2.205e-158	513.0	COG1653@1|root,COG1653@2|Bacteria,2G7RQ@200795|Chloroflexi,377M8@32061|Chloroflexia	32061|Chloroflexia	G	PFAM extracellular solute-binding protein family 1	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_1,SBP_bac_8
CMS1_k127_6155978_2	357808.RoseRS_3618	1.048e-181	596.0	COG0421@1|root,COG4262@1|root,COG0421@2|Bacteria,COG4262@2|Bacteria	2|Bacteria	H	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	MFS_1,Spermine_synt_N,Spermine_synth
CMS1_k127_6155978_10	926550.CLDAP_03310	4.67e-91	306.0	COG1082@1|root,COG1082@2|Bacteria,2G9Q1@200795|Chloroflexi	2|Bacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS1_k127_6155978_3	926569.ANT_08280	5.1e-161	514.0	COG0673@1|root,COG0673@2|Bacteria,2G8AS@200795|Chloroflexi	200795|Chloroflexi	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_6155978_1	926550.CLDAP_05160	1.099e-185	595.0	COG5305@1|root,COG5305@2|Bacteria,2G7EE@200795|Chloroflexi	2|Bacteria	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS1_k127_6155978_13	1200792.AKYF01000012_gene1279	4.951e-75	258.0	COG0500@1|root,COG2226@2|Bacteria,1VR4R@1239|Firmicutes,4HUAS@91061|Bacilli,27563@186822|Paenibacillaceae	91061|Bacilli	Q	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS1_k127_6155978_20	595494.Tola_1479	8.595e-22	108.0	COG1994@1|root,COG1994@2|Bacteria,1NSFF@1224|Proteobacteria,1S4N8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
CMS1_k127_6155978_16	926569.ANT_20740	1.878e-59	211.0	COG1595@1|root,COG1595@2|Bacteria,2G6X7@200795|Chloroflexi	200795|Chloroflexi	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_6155978_15	697284.ERIC2_c22620	8.51e-62	223.0	COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,4HBIR@91061|Bacilli,26S8K@186822|Paenibacillaceae	91061|Bacilli	S	DegV family	degV3	-	-	-	-	-	-	-	-	-	-	-	DegV
CMS1_k127_6155978_9	656519.Halsa_1105	7.574e-110	368.0	COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,248V8@186801|Clostridia,3WAA2@53433|Halanaerobiales	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
CMS1_k127_6155978_0	926569.ANT_15410	2.888e-265	845.0	COG1199@1|root,COG2176@1|root,COG1199@2|Bacteria,COG2176@2|Bacteria,2G5P4@200795|Chloroflexi	200795|Chloroflexi	L	PFAM Exonuclease, RNase T and DNA polymerase III	-	-	2.7.7.7,3.6.4.12	ko:K02342,ko:K03722	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,RNase_T
CMS1_k127_6155978_8	479434.Sthe_2126	1.301e-118	390.0	COG0714@1|root,COG0714@2|Bacteria,2G669@200795|Chloroflexi,27YUB@189775|Thermomicrobia	189775|Thermomicrobia	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS1_k127_6155978_19	324602.Caur_3595	7.405e-22	101.0	COG0664@1|root,COG0664@2|Bacteria,2GBTI@200795|Chloroflexi,375RB@32061|Chloroflexia	32061|Chloroflexia	T	PFAM cyclic nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
CMS1_k127_6155978_5	324602.Caur_0673	2.562e-150	506.0	COG0318@1|root,COG0318@2|Bacteria,2G5Q8@200795|Chloroflexi,376GY@32061|Chloroflexia	32061|Chloroflexia	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
CMS1_k127_6155978_14	525904.Tter_1028	2.981e-62	228.0	COG0305@1|root,COG0305@2|Bacteria	2|Bacteria	L	Participates in initiation and elongation during chromosome replication	-	-	3.6.4.12	ko:K02314,ko:K02316,ko:K17680	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03029,ko03032	-	-	-	DnaB_C,Toprim_2,Toprim_N,zf-CHC2
CMS1_k127_6155978_6	1128421.JAGA01000002_gene1437	8.855e-139	449.0	COG0714@1|root,COG0714@2|Bacteria	2|Bacteria	KLT	Associated with various cellular activities	MA20_34740	-	-	-	-	-	-	-	-	-	-	-	AAA_5
CMS1_k127_6155978_7	316274.Haur_0047	1.362e-132	439.0	COG3552@1|root,COG3552@2|Bacteria,2G60I@200795|Chloroflexi,3757T@32061|Chloroflexia	32061|Chloroflexia	S	PFAM VWA containing CoxE family protein	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
CMS1_k127_6155978_18	316274.Haur_1215	3.709e-36	140.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	-	-	2.1.1.80,2.7.13.3,3.1.1.61	ko:K02030,ko:K03407,ko:K07679,ko:K11443,ko:K13924	ko02020,ko02030,ko04112,ko05133,map02020,map02030,map04112,map05133	M00236,M00477,M00506,M00511	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02000,ko02022,ko02035	3.A.1.3	-	-	CHASE3,HATPase_c,HisKA,NMT1,PAS_3,PAS_9,Response_reg,SBP_bac_3
CMS1_k127_6155978_21	1336803.PHEL49_1212	2.75e-15	89.0	COG3629@1|root,COG3629@2|Bacteria,4P0JF@976|Bacteroidetes,1I8ER@117743|Flavobacteriia,3VW21@52959|Polaribacter	976|Bacteroidetes	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD
CMS1_k127_6155978_17	1121396.KB893071_gene1279	7.348e-54	201.0	COG1235@1|root,COG1235@2|Bacteria,1NW4Z@1224|Proteobacteria,42PTI@68525|delta/epsilon subdivisions,2WIWT@28221|Deltaproteobacteria,2MIKY@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
CMS1_k127_6155978_11	926550.CLDAP_02720	3.653e-83	287.0	COG1577@1|root,COG1577@2|Bacteria,2G6DY@200795|Chloroflexi	200795|Chloroflexi	I	TIGRFAM mevalonate kinase	mvk	-	2.7.1.36	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	M00095	R02245	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
CMS1_k127_6155978_12	517418.Ctha_1556	7.639e-82	284.0	COG0490@1|root,COG1226@1|root,COG0490@2|Bacteria,COG1226@2|Bacteria,1FD8F@1090|Chlorobi	1090|Chlorobi	P	Ion transport 2 domain protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
CMS1_k127_6159998_0	63737.Npun_R6406	2.131e-166	537.0	COG0641@1|root,COG0641@2|Bacteria	2|Bacteria	C	radical SAM	hxsB	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM
CMS1_k127_6159998_1	926569.ANT_24710	3.748e-90	301.0	COG2041@1|root,COG2041@2|Bacteria,2G6ES@200795|Chloroflexi	200795|Chloroflexi	S	PFAM oxidoreductase, molybdopterin binding	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
CMS1_k127_6159998_2	100226.SCO0153	7.45e-12	66.0	COG1672@1|root,COG1672@2|Bacteria,2IGAA@201174|Actinobacteria	201174|Actinobacteria	S	Electron transfer DM13	-	-	-	-	-	-	-	-	-	-	-	-	DM13
CMS1_k127_6196351_0	1303518.CCALI_01048	1.865e-137	443.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
CMS1_k127_6196351_7	641491.DND132_2149	8.414e-06	57.0	COG1413@1|root,COG1413@2|Bacteria,1QE7F@1224|Proteobacteria,435WT@68525|delta/epsilon subdivisions,2X0D6@28221|Deltaproteobacteria,2MBW1@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
CMS1_k127_6196351_3	306281.AJLK01000204_gene5212	3.975e-111	377.0	COG0443@1|root,COG0443@2|Bacteria,1G26I@1117|Cyanobacteria,1JI6N@1189|Stigonemataceae	1117|Cyanobacteria	O	MreB/Mbl protein	-	-	-	-	-	-	-	-	-	-	-	-	HSP70
CMS1_k127_6196351_2	1122915.AUGY01000030_gene7744	3.545e-128	418.0	COG1052@1|root,COG1052@2|Bacteria	2|Bacteria	CH	NAD binding	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
CMS1_k127_6196351_4	357808.RoseRS_4052	6.102e-111	368.0	COG0002@1|root,COG0002@2|Bacteria,2G6D0@200795|Chloroflexi,3759I@32061|Chloroflexia	32061|Chloroflexia	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
CMS1_k127_6196351_6	357808.RoseRS_4053	8.361e-69	243.0	COG0548@1|root,COG0548@2|Bacteria,2G6ZG@200795|Chloroflexi,375PI@32061|Chloroflexia	32061|Chloroflexia	F	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
CMS1_k127_6196351_1	926550.CLDAP_16930	2.577e-135	441.0	COG4992@1|root,COG4992@2|Bacteria,2G5TW@200795|Chloroflexi	200795|Chloroflexi	E	TIGRFAM acetylornithine and succinylornithine aminotransferase	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CMS1_k127_6196351_5	1128421.JAGA01000003_gene3443	5.443e-100	336.0	COG1364@1|root,COG1364@2|Bacteria,2NQKS@2323|unclassified Bacteria	2|Bacteria	E	ArgJ family	argJ	GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,2.3.1.35,2.7.2.8	ko:K00620,ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282,R02649	RC00002,RC00004,RC00043,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
CMS1_k127_6202260_1	266117.Rxyl_0343	6.392e-89	300.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	2.1.1.301	ko:K21459	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_25
CMS1_k127_6202260_3	518766.Rmar_2862	0.0007114	47.0	COG2161@1|root,COG2161@2|Bacteria	2|Bacteria	D	toxin-antitoxin pair type II binding	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
CMS1_k127_6202260_2	370438.PTH_0703	4.455e-25	109.0	COG5611@1|root,COG5611@2|Bacteria,1V8UV@1239|Firmicutes,24KGR@186801|Clostridia	186801|Clostridia	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
CMS1_k127_6202260_0	926550.CLDAP_07090	4.424e-178	569.0	COG0665@1|root,COG0665@2|Bacteria	2|Bacteria	E	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity	-	-	1.5.3.1	ko:K00303	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
CMS1_k127_6206002_4	926569.ANT_13340	3.294e-161	545.0	COG1472@1|root,COG1472@2|Bacteria,2G7PD@200795|Chloroflexi	200795|Chloroflexi	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
CMS1_k127_6206002_2	485913.Krac_0006	4.625e-167	535.0	COG1219@1|root,COG1219@2|Bacteria,2G661@200795|Chloroflexi	200795|Chloroflexi	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
CMS1_k127_6206002_13	926550.CLDAP_06940	2.036e-79	269.0	COG0740@1|root,COG0740@2|Bacteria,2G6BN@200795|Chloroflexi	200795|Chloroflexi	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
CMS1_k127_6206002_14	926550.CLDAP_06930	1.019e-59	226.0	COG0544@1|root,COG0544@2|Bacteria,2G6GA@200795|Chloroflexi	200795|Chloroflexi	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
CMS1_k127_6206002_7	1547437.LL06_15680	2.032e-117	390.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TR7Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
CMS1_k127_6206002_3	926569.ANT_04950	2.185e-164	527.0	COG0183@1|root,COG0183@2|Bacteria,2G5YW@200795|Chloroflexi	200795|Chloroflexi	I	Belongs to the thiolase family	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
CMS1_k127_6206002_1	1163617.SCD_n00024	2.246e-214	672.0	COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,2VH4U@28216|Betaproteobacteria	28216|Betaproteobacteria	E	lysine 2,3-aminomutase	-	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,LAM_C,Radical_SAM
CMS1_k127_6206002_11	485913.Krac_10666	1.862e-94	325.0	COG0436@1|root,COG0436@2|Bacteria,2G5MC@200795|Chloroflexi	2|Bacteria	E	aminotransferase class I and II	aspC	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS1_k127_6206002_12	63737.Npun_F6039	1.208e-92	323.0	COG1100@1|root,COG4886@1|root,COG1100@2|Bacteria,COG4886@2|Bacteria,1G05B@1117|Cyanobacteria,1HJS7@1161|Nostocales	1117|Cyanobacteria	S	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,COR,LRR_4,LRR_8,Roc,TIR_2
CMS1_k127_6206002_10	391595.RLO149_c021540	2.653e-95	318.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2TSA6@28211|Alphaproteobacteria,2P11B@2433|Roseobacter	28211|Alphaproteobacteria	E	COG0410 ABC-type branched-chain amino acid transport systems, ATPase component	MA20_22615	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
CMS1_k127_6206002_9	391613.RTM1035_07023	6.151e-102	338.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,2TUQB@28211|Alphaproteobacteria,46RVU@74030|Roseovarius	28211|Alphaproteobacteria	E	COG0411 ABC-type branched-chain amino acid transport systems, ATPase component	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
CMS1_k127_6206002_8	391595.RLO149_c021560	1.888e-113	379.0	COG4177@1|root,COG4177@2|Bacteria,1RD1T@1224|Proteobacteria,2UAJ3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	COG4177 ABC-type branched-chain amino acid transport system, permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
CMS1_k127_6206002_5	391613.RTM1035_07013	3.967e-156	502.0	COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,2TRMA@28211|Alphaproteobacteria,46PPX@74030|Roseovarius	28211|Alphaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
CMS1_k127_6206002_6	391613.RTM1035_07008	2.743e-139	458.0	COG0683@1|root,COG0683@2|Bacteria,1MXPJ@1224|Proteobacteria,2TSZ5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
CMS1_k127_6206002_16	670487.Ocepr_0856	3.761e-06	59.0	COG1652@1|root,COG1652@2|Bacteria	2|Bacteria	S	positive regulation of growth rate	-	-	-	-	-	-	-	-	-	-	-	-	LysM
CMS1_k127_6206002_15	1131269.AQVV01000025_gene2327	1.805e-42	169.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	FGE-sulfatase,HTH_31
CMS1_k127_6206002_0	926569.ANT_24980	3.018e-255	812.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,2G5QR@200795|Chloroflexi	200795|Chloroflexi	J	phenylalanyl-tRNA synthetase beta subunit	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
CMS1_k127_6207214_2	1121924.ATWH01000001_gene4463	2.484e-26	119.0	COG1266@1|root,COG1266@2|Bacteria,2I8AH@201174|Actinobacteria,4FREE@85023|Microbacteriaceae	201174|Actinobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
CMS1_k127_6207214_1	1009370.ALO_00950	5.124e-46	184.0	COG0577@1|root,COG0577@2|Bacteria,1U388@1239|Firmicutes,4H32X@909932|Negativicutes	909932|Negativicutes	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS1_k127_6207214_0	357808.RoseRS_1075	3.978e-73	263.0	COG0577@1|root,COG0577@2|Bacteria,2G68F@200795|Chloroflexi,376ZY@32061|Chloroflexia	32061|Chloroflexia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS1_k127_6210978_5	479434.Sthe_1139	2.581e-24	111.0	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	-	ko:K02847	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	9.B.67.4,9.B.67.5	-	-	Wzy_C
CMS1_k127_6210978_0	479434.Sthe_1140	9.127e-158	507.0	COG0399@1|root,COG0399@2|Bacteria,2G7J4@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
CMS1_k127_6210978_1	479434.Sthe_1141	4.902e-135	439.0	COG0673@1|root,COG0673@2|Bacteria,2G6PI@200795|Chloroflexi	200795|Chloroflexi	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_6210978_2	479434.Sthe_1142	1.507e-80	274.0	COG2148@1|root,COG2148@2|Bacteria,2G66B@200795|Chloroflexi,27XNK@189775|Thermomicrobia	200795|Chloroflexi	M	PFAM sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
CMS1_k127_6210978_3	479434.Sthe_1143	1.765e-80	284.0	COG0489@1|root,COG3944@1|root,COG0489@2|Bacteria,COG3944@2|Bacteria,2G5WM@200795|Chloroflexi	200795|Chloroflexi	DM	PFAM lipopolysaccharide biosynthesis protein	-	-	2.7.10.2	ko:K08253	-	-	-	-	ko00000,ko01000	-	-	-	CbiA,GNVR,Wzz
CMS1_k127_6210978_4	1502724.FF80_03561	2.867e-44	168.0	COG4225@1|root,COG4225@2|Bacteria,1N5V1@1224|Proteobacteria,2UTQQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Heparinase II/III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III
CMS1_k127_6219346_2	42256.RradSPS_0358	2.817e-29	120.0	COG2909@1|root,COG2909@2|Bacteria,2HENR@201174|Actinobacteria,4CPC9@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,AAA_22,GerE
CMS1_k127_6219346_3	479431.Namu_2376	1.239e-12	70.0	COG2909@1|root,COG2909@2|Bacteria,2I50W@201174|Actinobacteria,4EU8S@85013|Frankiales	201174|Actinobacteria	K	PFAM regulatory protein LuxR	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
CMS1_k127_6219346_0	797209.ZOD2009_21577	2.076e-184	603.0	COG0531@1|root,COG0589@1|root,arCOG00009@2157|Archaea,arCOG00449@2157|Archaea,2XTX6@28890|Euryarchaeota,23SWT@183963|Halobacteria	183963|Halobacteria	E	COG0531 Amino acid transporters	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease,AA_permease_2,Usp
CMS1_k127_6219346_1	936455.KI421499_gene711	1.342e-107	356.0	COG0329@1|root,COG0329@2|Bacteria,1PE99@1224|Proteobacteria,2TSAK@28211|Alphaproteobacteria,3JWWX@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	EM	Dihydrodipicolinate synthetase family	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
CMS1_k127_6219346_4	1229205.BUPH_08527	0.0005876	47.0	COG5659@1|root,COG5659@2|Bacteria,1MWAV@1224|Proteobacteria,2W56T@28216|Betaproteobacteria,1KIBA@119060|Burkholderiaceae	28216|Betaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
CMS1_k127_6221399_4	383372.Rcas_2452	4.012e-122	398.0	COG1173@1|root,COG1173@2|Bacteria,2G7U9@200795|Chloroflexi,377XX@32061|Chloroflexia	32061|Chloroflexia	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
CMS1_k127_6221399_1	390874.Tpet_1677	1.184e-148	494.0	COG0747@1|root,COG0747@2|Bacteria,2GCNZ@200918|Thermotogae	200918|Thermotogae	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_6221399_3	390874.Tpet_1683	2.249e-133	432.0	COG0601@1|root,COG0601@2|Bacteria	2|Bacteria	P	nitrogen compound transport	oppB	-	2.4.2.7	ko:K00759,ko:K02033	ko00230,ko01100,ko02024,map00230,map01100,map02024	M00239	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko00002,ko01000,ko02000,ko04147	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_6221399_0	383372.Rcas_2452	1.782e-158	508.0	COG1173@1|root,COG1173@2|Bacteria,2G7U9@200795|Chloroflexi,377XX@32061|Chloroflexia	32061|Chloroflexia	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
CMS1_k127_6221399_13	485914.Hmuk_0567	1.237e-74	258.0	COG5285@1|root,arCOG09157@2157|Archaea,2XTXQ@28890|Euryarchaeota,23V37@183963|Halobacteria	183963|Halobacteria	Q	COG5285 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
CMS1_k127_6221399_9	794903.OPIT5_11265	6.899e-86	296.0	COG0673@1|root,COG0673@2|Bacteria,46YAS@74201|Verrucomicrobia,3K98D@414999|Opitutae	414999|Opitutae	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_6221399_10	1236973.JCM9157_2323	1.069e-85	290.0	COG1082@1|root,COG1082@2|Bacteria,1TRXP@1239|Firmicutes,4HC31@91061|Bacilli,1ZJIU@1386|Bacillus	91061|Bacilli	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS1_k127_6221399_5	926550.CLDAP_21490	8.694e-111	364.0	COG1082@1|root,COG1082@2|Bacteria,2G6J3@200795|Chloroflexi	200795|Chloroflexi	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS1_k127_6221399_7	935948.KE386495_gene1412	9.828e-100	333.0	COG1082@1|root,COG1082@2|Bacteria,1TSK3@1239|Firmicutes,24DCC@186801|Clostridia,42FNF@68295|Thermoanaerobacterales	186801|Clostridia	G	PFAM Xylose isomerase domain-containing protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS1_k127_6221399_8	1521187.JPIM01000144_gene3346	1.943e-94	315.0	COG4636@1|root,COG4636@2|Bacteria,2G98P@200795|Chloroflexi,3772T@32061|Chloroflexia	32061|Chloroflexia	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
CMS1_k127_6221399_6	324057.Pjdr2_0782	5.436e-110	367.0	COG4948@1|root,COG4948@2|Bacteria,1TS0S@1239|Firmicutes,4HC1G@91061|Bacilli,26VB1@186822|Paenibacillaceae	91061|Bacilli	M	mandelate racemase muconate lactonizing	-	-	4.2.1.6	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R03033	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
CMS1_k127_6221399_2	357808.RoseRS_4146	1.724e-135	441.0	COG1960@1|root,COG1960@2|Bacteria,2G65J@200795|Chloroflexi,374Z5@32061|Chloroflexia	32061|Chloroflexia	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
CMS1_k127_6221399_16	1410617.JHXH01000005_gene1090	2.148e-12	78.0	2DHAX@1|root,32U8Z@2|Bacteria,1VV1S@1239|Firmicutes,250GD@186801|Clostridia,3WM8Y@541000|Ruminococcaceae	186801|Clostridia	S	Zinc finger domain	-	-	-	-	-	-	-	-	-	-	-	-	DZR
CMS1_k127_6221399_14	1122919.KB905551_gene1682	1.679e-66	243.0	COG3828@1|root,COG3828@2|Bacteria	2|Bacteria	N	Trehalose utilisation	-	-	-	-	-	-	-	-	-	-	-	-	PmoA
CMS1_k127_6221399_12	1123242.JH636437_gene6142	3.28e-79	273.0	COG1082@1|root,COG1082@2|Bacteria,2IXNX@203682|Planctomycetes	203682|Planctomycetes	G	COG1082 Sugar phosphate	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
CMS1_k127_6221399_11	886293.Sinac_3103	1.156e-83	285.0	COG1082@1|root,COG1082@2|Bacteria,2IZ3D@203682|Planctomycetes	203682|Planctomycetes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS1_k127_6221399_15	1121904.ARBP01000040_gene522	9.21e-34	131.0	COG0823@1|root,COG0823@2|Bacteria,4NQ0C@976|Bacteroidetes,47PP7@768503|Cytophagia	976|Bacteroidetes	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_625459_2	926550.CLDAP_34690	1.628e-11	65.0	COG0075@1|root,COG0075@2|Bacteria,2G5P3@200795|Chloroflexi	200795|Chloroflexi	E	PFAM aminotransferase class V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
CMS1_k127_625459_1	326427.Cagg_0281	2.371e-41	162.0	COG1028@1|root,COG1028@2|Bacteria,2G5KB@200795|Chloroflexi,3759E@32061|Chloroflexia	32061|Chloroflexia	IQ	short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS1_k127_625459_0	321332.CYB_2088	4.805e-162	525.0	COG3119@1|root,COG3119@2|Bacteria,1G35S@1117|Cyanobacteria,1H28E@1129|Synechococcus	1117|Cyanobacteria	P	Sulfatase	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase,Sulfatase_C
CMS1_k127_6256771_1	1121382.JQKG01000005_gene3282	4.078e-59	216.0	COG0249@1|root,COG0249@2|Bacteria,1WJFP@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	ATPase domain of DNA mismatch repair MUTS family	-	-	-	-	-	-	-	-	-	-	-	-	MutS_V
CMS1_k127_6256771_3	1463879.JOHP01000016_gene4743	2.507e-11	72.0	COG4106@1|root,COG4106@2|Bacteria,2GK0K@201174|Actinobacteria	201174|Actinobacteria	S	Methyltransferase	metZ	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS1_k127_6256771_0	1246459.KB898354_gene5108	4.211e-93	319.0	COG0665@1|root,COG0665@2|Bacteria,1R652@1224|Proteobacteria,2TV72@28211|Alphaproteobacteria,4B7D6@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Glycine D-amino acid oxidases (deaminating)	-	-	-	-	-	-	-	-	-	-	-	-	DAO
CMS1_k127_6256771_2	1173026.Glo7428_4685	1.168e-47	186.0	COG1664@1|root,COG1664@2|Bacteria,1G2TI@1117|Cyanobacteria	1117|Cyanobacteria	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
CMS1_k127_626494_0	485913.Krac_4915	2.798e-180	572.0	COG1249@1|root,COG1249@2|Bacteria,2G5VW@200795|Chloroflexi	200795|Chloroflexi	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	merA	-	1.16.1.1	ko:K00520	-	-	-	-	ko00000,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
CMS1_k127_626494_2	118166.JH976538_gene5295	3.527e-48	179.0	COG3861@1|root,COG3861@2|Bacteria,1GE1R@1117|Cyanobacteria	1117|Cyanobacteria	S	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_626494_1	269799.Gmet_2436	2.289e-87	304.0	COG0642@1|root,COG2205@2|Bacteria,1MUZQ@1224|Proteobacteria,42NZF@68525|delta/epsilon subdivisions,2WJNR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,GAF_3,HATPase_c,HisKA,KdpD,Usp
CMS1_k127_6277518_0	765420.OSCT_2763	2.951e-60	214.0	COG4753@1|root,COG4963@1|root,COG4753@2|Bacteria,COG4963@2|Bacteria,2G6CH@200795|Chloroflexi,37524@32061|Chloroflexia	32061|Chloroflexia	D	PFAM response regulator receiver	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,ParA,Response_reg
CMS1_k127_6277518_1	926569.ANT_20630	1.215e-41	167.0	COG3745@1|root,COG3745@2|Bacteria	2|Bacteria	U	Flp pilus assembly protein CpaB	cpaB	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	RcpC,SAF
CMS1_k127_6277518_2	1230460.C495_06943	7.593e-06	56.0	COG2304@1|root,arCOG07561@1|root,arCOG02902@2157|Archaea,arCOG07561@2157|Archaea,2XVVH@28890|Euryarchaeota,23SGN@183963|Halobacteria	183963|Halobacteria	K	protein containing a von Willebrand factor type A (vWA) domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA
CMS1_k127_637355_3	661478.OP10G_3512	1.689e-27	113.0	COG1619@1|root,COG1619@2|Bacteria	2|Bacteria	V	carboxypeptidase activity	-	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
CMS1_k127_637355_1	99598.Cal7507_2327	6.514e-84	287.0	COG2084@1|root,COG2084@2|Bacteria,1GFKR@1117|Cyanobacteria,1HMUH@1161|Nostocales	1117|Cyanobacteria	I	Domain of unknown function (DUF1932)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1932,NAD_binding_2
CMS1_k127_637355_0	402777.KB235903_gene1681	2.405e-292	909.0	COG1506@1|root,COG1506@2|Bacteria,1G200@1117|Cyanobacteria,1H8T3@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Prolyl oligopeptidase family	dap2	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
CMS1_k127_637355_6	1392502.JNIO01000008_gene1336	6.681e-08	64.0	COG3023@1|root,COG3023@2|Bacteria,1V7WT@1239|Firmicutes,4H4PE@909932|Negativicutes	909932|Negativicutes	V	Ami_2	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2
CMS1_k127_637355_4	666685.R2APBS1_3743	2.236e-11	75.0	COG1652@1|root,COG1652@2|Bacteria,1N3P8@1224|Proteobacteria,1SY85@1236|Gammaproteobacteria,1X82C@135614|Xanthomonadales	135614|Xanthomonadales	S	peptidoglycan-binding protein, lysm	-	-	-	-	-	-	-	-	-	-	-	-	LysM
CMS1_k127_637355_5	382464.ABSI01000005_gene1155	2.368e-11	72.0	COG0431@1|root,COG0431@2|Bacteria,46T7B@74201|Verrucomicrobia	74201|Verrucomicrobia	S	NADPH-dependent FMN reductase	-	-	1.5.1.38	ko:K00299	ko00740,ko00920,ko01100,map00740,map00920,map01100	-	R05706,R07210,R10206	RC00126,RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	FMN_red
CMS1_k127_637355_2	269797.Mbar_A2910	2.416e-51	201.0	COG0477@1|root,arCOG00132@2157|Archaea,2XYHV@28890|Euryarchaeota,2NAK2@224756|Methanomicrobia	224756|Methanomicrobia	G	MFS/sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_640747_2	1379270.AUXF01000001_gene1884	9.214e-42	164.0	COG2367@1|root,COG2367@2|Bacteria	2|Bacteria	V	Beta-lactamase	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
CMS1_k127_640747_1	1183438.GKIL_3794	1.288e-49	183.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	yokL	-	-	ko:K03825	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_4,Acetyltransf_7
CMS1_k127_640747_0	1121935.AQXX01000064_gene3308	3.774e-139	451.0	COG4257@1|root,COG4257@2|Bacteria,1QR8W@1224|Proteobacteria,1RQM4@1236|Gammaproteobacteria,1XPTW@135619|Oceanospirillales	135619|Oceanospirillales	V	Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid	-	-	-	ko:K18235	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	-
CMS1_k127_640747_3	318167.Sfri_3700	6.023e-08	55.0	COG2208@1|root,COG2208@2|Bacteria,1N4K5@1224|Proteobacteria,1RNYP@1236|Gammaproteobacteria,2QB3I@267890|Shewanellaceae	1236|Gammaproteobacteria	T	SMART protein phosphatase 2C domain protein	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HATPase_c_2,Response_reg,SpoIIE
CMS1_k127_651018_0	383372.Rcas_4064	6.887e-72	252.0	COG3039@1|root,COG3039@2|Bacteria,2G9I4@200795|Chloroflexi	200795|Chloroflexi	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_3
CMS1_k127_654274_0	1286093.C266_25740	1.798e-35	138.0	COG2423@1|root,COG2423@2|Bacteria,1MWH6@1224|Proteobacteria,2WFNZ@28216|Betaproteobacteria,1KI4E@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Ornithine cyclodeaminase/mu-crystallin family	-	-	-	-	-	-	-	-	-	-	-	-	OCD_Mu_crystall
CMS1_k127_65887_0	670487.Ocepr_1024	1.514e-26	121.0	COG4758@1|root,COG4758@2|Bacteria	2|Bacteria	KT	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2154,Toast_rack_N
CMS1_k127_65887_1	926569.ANT_26890	3.294e-26	115.0	COG1595@1|root,COG1595@2|Bacteria,2G6X7@200795|Chloroflexi	2|Bacteria	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS1_k127_684177_5	1408473.JHXO01000008_gene2655	8.825e-08	55.0	COG0330@1|root,COG0330@2|Bacteria,4NH8V@976|Bacteroidetes,2FQPC@200643|Bacteroidia	976|Bacteroidetes	O	SPFH Band 7 PHB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
CMS1_k127_684177_2	926550.CLDAP_28530	2.548e-32	132.0	COG0589@1|root,COG0589@2|Bacteria,2G91P@200795|Chloroflexi	200795|Chloroflexi	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS1_k127_684177_0	1499967.BAYZ01000103_gene3778	7.537e-284	902.0	COG1352@1|root,COG2201@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria	2|Bacteria	NT	protein-glutamate methylesterase activity	cheB	-	2.1.1.80,3.1.1.61,3.5.1.44	ko:K03412,ko:K03413,ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,PAS,PAS_10,PAS_4,PAS_9,Response_reg
CMS1_k127_684177_1	765911.Thivi_4106	6.469e-69	250.0	COG2202@1|root,COG4585@1|root,COG2202@2|Bacteria,COG4585@2|Bacteria,1R6KY@1224|Proteobacteria,1S485@1236|Gammaproteobacteria,1WZHA@135613|Chromatiales	135613|Chromatiales	T	Histidine kinase	-	-	2.7.13.3	ko:K07675	ko02020,map02020	M00473	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3,PAS_4
CMS1_k127_684177_4	945713.IALB_2602	8.17e-08	54.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	vsrD	-	-	ko:K02282,ko:K07689	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	M00475	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	GerE,Response_reg
CMS1_k127_684177_3	1128421.JAGA01000002_gene949	3.456e-32	127.0	COG2261@1|root,COG2261@2|Bacteria	2|Bacteria	S	Transglycosylase associated protein	mltA	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
CMS1_k127_71237_7	1087481.AGFX01000012_gene3324	3.719e-44	165.0	COG0395@1|root,COG0395@2|Bacteria,1UCH2@1239|Firmicutes,4I78I@91061|Bacilli,26W7F@186822|Paenibacillaceae	91061|Bacilli	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_71237_5	324602.Caur_2727	2.038e-76	275.0	COG1621@1|root,COG1621@2|Bacteria,2G6WG@200795|Chloroflexi	200795|Chloroflexi	G	Glycosyl hydrolases family 32	-	-	3.2.1.26,3.2.1.80	ko:K01193,ko:K03332	ko00051,ko00052,ko00500,ko01100,map00051,map00052,map00500,map01100	-	R00801,R00802,R00879,R02410,R03635,R03921,R06088	RC00028,RC00077	ko00000,ko00001,ko01000	-	GH32	-	Glyco_hydro_32C,Glyco_hydro_32N
CMS1_k127_71237_8	530564.Psta_3684	1.913e-22	99.0	COG1977@1|root,COG1977@2|Bacteria,2J1I1@203682|Planctomycetes	203682|Planctomycetes	H	COG1977 Molybdopterin converting factor, small subunit	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
CMS1_k127_71237_0	926550.CLDAP_06490	1.479e-274	865.0	COG1529@1|root,COG1529@2|Bacteria,2G65D@200795|Chloroflexi	200795|Chloroflexi	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
CMS1_k127_71237_6	926550.CLDAP_06500	6.45e-68	234.0	COG2080@1|root,COG2080@2|Bacteria,2G6NT@200795|Chloroflexi	200795|Chloroflexi	C	2Fe-2S -binding domain protein	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
CMS1_k127_71237_4	926550.CLDAP_06510	7.991e-89	301.0	COG1319@1|root,COG1319@2|Bacteria,2G8QI@200795|Chloroflexi	200795|Chloroflexi	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
CMS1_k127_71237_2	113395.AXAI01000005_gene3866	6.908e-118	386.0	COG3836@1|root,COG3836@2|Bacteria,1R9U6@1224|Proteobacteria,2TSTY@28211|Alphaproteobacteria,3K39R@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	HpcH/HpaI aldolase/citrate lyase family	-	-	-	-	-	-	-	-	-	-	-	-	HpcH_HpaI
CMS1_k127_71237_9	1303518.CCALI_02277	4.587e-11	73.0	COG2220@1|root,COG2220@2|Bacteria	2|Bacteria	S	N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity	ulaG	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
CMS1_k127_71237_1	161934.XP_010690360.1	9.299e-166	531.0	COG1052@1|root,KOG0069@2759|Eukaryota,37ISZ@33090|Viridiplantae,3GC69@35493|Streptophyta	35493|Streptophyta	C	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	HPR	GO:0001101,GO:0003674,GO:0003676,GO:0003723,GO:0003727,GO:0003824,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005829,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008187,GO:0008266,GO:0008465,GO:0009314,GO:0009414,GO:0009415,GO:0009416,GO:0009507,GO:0009536,GO:0009605,GO:0009628,GO:0009853,GO:0009854,GO:0009987,GO:0009991,GO:0010035,GO:0016491,GO:0016614,GO:0016616,GO:0016618,GO:0030267,GO:0031668,GO:0033554,GO:0042221,GO:0042579,GO:0042631,GO:0043094,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048046,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071214,GO:0071229,GO:0071462,GO:0071478,GO:0071482,GO:0071496,GO:0097159,GO:0104004,GO:1901363,GO:1901700,GO:1901701	-	ko:K15893	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01388	RC00031	ko00000,ko00001,ko00002	-	-	-	2-Hacid_dh,2-Hacid_dh_C
CMS1_k127_71237_3	661478.OP10G_1120	1.617e-90	305.0	COG5285@1|root,COG5285@2|Bacteria	2|Bacteria	Q	dioxygenase activity	-	-	1.14.11.18	ko:K00477	ko04146,map04146	-	-	-	ko00000,ko00001,ko01000	-	-	-	PhyH
CMS1_k127_7156_6	1528106.JRJE01000031_gene3353	8.533e-46	174.0	COG0730@1|root,COG0730@2|Bacteria,1MVY3@1224|Proteobacteria,2TU6M@28211|Alphaproteobacteria,2JRRQ@204441|Rhodospirillales	204441|Rhodospirillales	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
CMS1_k127_7156_0	926550.CLDAP_09060	4.302e-151	488.0	COG0624@1|root,COG0624@2|Bacteria,2G8FI@200795|Chloroflexi	200795|Chloroflexi	E	peptidase dimerisation domain protein	-	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
CMS1_k127_7156_2	864069.MicloDRAFT_00027630	1.247e-100	338.0	COG3191@1|root,COG3191@2|Bacteria,1MWDP@1224|Proteobacteria,2TRDC@28211|Alphaproteobacteria,1JRNB@119045|Methylobacteriaceae	28211|Alphaproteobacteria	EQ	PFAM peptidase S58 DmpA	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S58
CMS1_k127_7156_1	1521187.JPIM01000037_gene3879	4.437e-102	339.0	COG0414@1|root,COG0414@2|Bacteria,2G64N@200795|Chloroflexi,374TX@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
CMS1_k127_7156_3	768706.Desor_3351	5.734e-98	329.0	COG0413@1|root,COG0413@2|Bacteria,1TPZA@1239|Firmicutes,248RR@186801|Clostridia,260CY@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	-	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
CMS1_k127_7156_4	765420.OSCT_0762	1.079e-82	284.0	COG1893@1|root,COG1893@2|Bacteria,2G9PB@200795|Chloroflexi,3772C@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
CMS1_k127_7156_5	926550.CLDAP_25300	3.526e-51	197.0	COG1819@1|root,COG1819@2|Bacteria	2|Bacteria	CG	transferase activity, transferring hexosyl groups	-	-	-	ko:K18101	ko02024,ko02025,map02024,map02025	-	-	-	ko00000,ko00001,ko01000,ko01003	-	GT1	-	Glyco_tran_28_C,Glyco_transf_28,UDPGT
CMS1_k127_75730_3	56107.Cylst_1158	1.61e-69	239.0	COG1404@1|root,COG1404@2|Bacteria,1G2T7@1117|Cyanobacteria,1HKA3@1161|Nostocales	1117|Cyanobacteria	O	TIGRFAM cyanobactin maturation protease, PatA PatG family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
CMS1_k127_75730_6	1116472.MGMO_8c00820	6.376e-28	115.0	2C82G@1|root,32RK9@2|Bacteria,1MZV5@1224|Proteobacteria,1SAWR@1236|Gammaproteobacteria,1XFGD@135618|Methylococcales	135618|Methylococcales	S	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
CMS1_k127_75730_2	266117.Rxyl_2946	1.807e-116	406.0	COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4CPZ0@84995|Rubrobacteria	84995|Rubrobacteria	T	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
CMS1_k127_75730_4	489825.LYNGBM3L_16340	3.202e-31	144.0	COG1672@1|root,COG2319@1|root,COG1672@2|Bacteria,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria,1H7DY@1150|Oscillatoriales	1117|Cyanobacteria	A	Wd40 repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_35,WD40
CMS1_k127_75730_0	489825.LYNGBM3L_52790	7.862e-123	437.0	COG5635@1|root,COG5635@2|Bacteria,1G14T@1117|Cyanobacteria,1H8RF@1150|Oscillatoriales	1117|Cyanobacteria	T	Ntpase (Nacht family)	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	NACHT,Pkinase,TIR_2
CMS1_k127_75730_5	765420.OSCT_1859	2.642e-29	138.0	COG4995@1|root,COG4995@2|Bacteria,2G8YF@200795|Chloroflexi,377C0@32061|Chloroflexia	200795|Chloroflexi	P	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,SIR2_2
CMS1_k127_75730_1	309801.trd_1951	1.972e-118	389.0	COG0601@1|root,COG0601@2|Bacteria,2GAQS@200795|Chloroflexi,27YWJ@189775|Thermomicrobia	189775|Thermomicrobia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_75730_7	309801.trd_1950	3.667e-18	87.0	COG1173@1|root,COG1173@2|Bacteria,2G8EC@200795|Chloroflexi,27YUP@189775|Thermomicrobia	189775|Thermomicrobia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_770695_3	926550.CLDAP_15140	8.228e-119	391.0	COG1653@1|root,COG1653@2|Bacteria,2G8MD@200795|Chloroflexi	200795|Chloroflexi	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K17234	ko02010,map02010	M00602	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.34	-	-	-
CMS1_k127_770695_8	710686.Mycsm_01877	0.0004605	44.0	COG1028@1|root,COG1028@2|Bacteria,2GP7P@201174|Actinobacteria,23EVA@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS1_k127_770695_2	479434.Sthe_0034	4.392e-126	415.0	COG0626@1|root,COG0626@2|Bacteria,2G684@200795|Chloroflexi,27Y2Y@189775|Thermomicrobia	189775|Thermomicrobia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.5.1.48,4.4.1.11	ko:K01739,ko:K01761	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00654,R00999,R01288,R02508,R03217,R03260,R04770,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00196,RC00348,RC00420,RC01209,RC01210,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
CMS1_k127_770695_4	66429.JOFL01000006_gene1938	3.375e-76	279.0	COG0823@1|root,COG0823@2|Bacteria,2GMNT@201174|Actinobacteria	201174|Actinobacteria	U	Periplasmic component of the Tol biopolymer transport system	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
CMS1_k127_770695_5	1082931.KKY_2561	5.388e-62	237.0	COG2342@1|root,COG2342@2|Bacteria,1N2HD@1224|Proteobacteria,2UEA7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Glycoside-hydrolase family GH114	-	-	6.1.1.16	ko:K01884	ko00970,map00970	M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Glyco_hydro_114,HemolysinCabind
CMS1_k127_770695_1	1121468.AUBR01000002_gene663	2.646e-126	420.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,42EUY@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	gltA	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
CMS1_k127_770695_7	272943.RSP_3670	1.454e-23	113.0	COG0673@1|root,COG0673@2|Bacteria,1MY5N@1224|Proteobacteria,2U0U7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	1.1.1.18,1.1.1.369	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	-	R01183,R09951	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA
CMS1_k127_770695_6	309801.trd_1313	6.73e-61	233.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2G67H@200795|Chloroflexi,27XI6@189775|Thermomicrobia	189775|Thermomicrobia	T	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
CMS1_k127_770695_0	479434.Sthe_0519	7.651e-127	417.0	COG4962@1|root,COG4962@2|Bacteria,2G68E@200795|Chloroflexi,27XTR@189775|Thermomicrobia	189775|Thermomicrobia	U	Type II/IV secretion system protein	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
CMS1_k127_774654_4	1385511.N783_16640	6.544e-32	130.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,4HBZ8@91061|Bacilli,2Y9SY@289201|Pontibacillus	91061|Bacilli	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
CMS1_k127_774654_2	562970.Btus_2621	1.548e-97	338.0	COG0672@1|root,COG0672@2|Bacteria,1TQIA@1239|Firmicutes,4HCJZ@91061|Bacilli,277XU@186823|Alicyclobacillaceae	91061|Bacilli	P	Iron permease FTR1 family	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	FTR1
CMS1_k127_774654_5	886293.Sinac_5984	3.698e-17	91.0	COG1082@1|root,COG1082@2|Bacteria,2IYUT@203682|Planctomycetes	203682|Planctomycetes	G	PFAM Xylose isomerase	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
CMS1_k127_774654_3	292459.STH2313	6.588e-86	294.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia	186801|Clostridia	P	ABC-type dipeptide oligopeptide nickel transport	-	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
CMS1_k127_774654_1	479434.Sthe_3428	1.438e-98	330.0	COG0601@1|root,COG0601@2|Bacteria,2G6BV@200795|Chloroflexi,27XFE@189775|Thermomicrobia	2|Bacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_774654_0	1054213.HMPREF9946_00347	6.083e-109	372.0	COG0747@1|root,COG0747@2|Bacteria,1P1HT@1224|Proteobacteria,2U18T@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	ABC transporter substrate-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
CMS1_k127_777898_6	446462.Amir_3822	3.023e-07	64.0	COG4932@1|root,COG4932@2|Bacteria,2I434@201174|Actinobacteria	201174|Actinobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,DUF11,SdrD_B
CMS1_k127_777898_5	511051.CSE_02410	4.927e-28	132.0	COG1361@1|root,COG3210@1|root,COG4719@1|root,COG1361@2|Bacteria,COG3210@2|Bacteria,COG4719@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11
CMS1_k127_777898_2	643648.Slip_1237	1.787e-78	280.0	COG1545@1|root,COG3425@1|root,COG1545@2|Bacteria,COG3425@2|Bacteria,1UDNN@1239|Firmicutes,24DF4@186801|Clostridia	186801|Clostridia	I	3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal	-	-	2.3.3.10	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	M00088,M00095	R01978	RC00004,RC00503	ko00000,ko00001,ko00002,ko01000	-	-	-	ACP_syn_III_C,DUF35_N,OB_aCoA_assoc
CMS1_k127_777898_0	1121468.AUBR01000090_gene747	8.078e-111	370.0	COG0183@1|root,COG0183@2|Bacteria,1TT8U@1239|Firmicutes,24AD9@186801|Clostridia	186801|Clostridia	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	DUF35_N,Thiolase_C,Thiolase_N,ketoacyl-synt
CMS1_k127_777898_1	867845.KI911784_gene3657	2.135e-81	278.0	COG0302@1|root,COG0302@2|Bacteria,2G6VZ@200795|Chloroflexi,375HB@32061|Chloroflexia	32061|Chloroflexia	H	PFAM GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
CMS1_k127_777898_4	396588.Tgr7_0327	2.393e-31	129.0	COG0801@1|root,COG0801@2|Bacteria,1RHNN@1224|Proteobacteria,1S62M@1236|Gammaproteobacteria,1WYX8@135613|Chromatiales	135613|Chromatiales	H	PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK	-	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
CMS1_k127_777898_3	344747.PM8797T_30012	4.478e-42	157.0	COG1539@1|root,COG1539@2|Bacteria	2|Bacteria	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folX	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008719,GO:0009987,GO:0016853,GO:0019752,GO:0034641,GO:0042558,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0071704,GO:1901360,GO:1901564	1.13.11.81,4.1.2.25,5.1.99.7,5.1.99.8	ko:K01633,ko:K07589	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073,R11082	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
CMS1_k127_77898_4	479434.Sthe_0949	2.58e-33	131.0	COG3870@1|root,COG3870@2|Bacteria,2G736@200795|Chloroflexi,27YHY@189775|Thermomicrobia	189775|Thermomicrobia	S	Cyclic-di-AMP receptor	-	-	-	-	-	-	-	-	-	-	-	-	CdAMP_rec
CMS1_k127_77898_2	926550.CLDAP_06830	4.375e-69	240.0	COG0125@1|root,COG0125@2|Bacteria,2G6G2@200795|Chloroflexi	200795|Chloroflexi	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
CMS1_k127_77898_1	926550.CLDAP_06820	3.586e-193	623.0	COG3854@1|root,COG3854@2|Bacteria,2G5P5@200795|Chloroflexi	200795|Chloroflexi	S	PFAM single-stranded nucleic acid binding R3H domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_30,R3H
CMS1_k127_77898_3	326427.Cagg_2938	3.632e-37	153.0	2E48V@1|root,32Z4P@2|Bacteria,2G7HY@200795|Chloroflexi,375NE@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_77898_0	864702.OsccyDRAFT_4021	9.527e-250	780.0	COG2256@1|root,COG2256@2|Bacteria,1G36R@1117|Cyanobacteria,1H9UW@1150|Oscillatoriales	1117|Cyanobacteria	L	ATPase family associated with various cellular activities (AAA)	mgs1	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
CMS1_k127_782287_5	998674.ATTE01000001_gene3907	3.254e-99	330.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,1RMK8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Branched-chain amino acid transport	livF3	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
CMS1_k127_782287_1	926550.CLDAP_14280	2.112e-157	511.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
CMS1_k127_782287_2	926550.CLDAP_14290	9.115e-150	481.0	COG4177@1|root,COG4177@2|Bacteria,2G6HP@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
CMS1_k127_782287_3	926550.CLDAP_14300	4.461e-134	434.0	COG0559@1|root,COG0559@2|Bacteria,2G6M5@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
CMS1_k127_782287_0	926550.CLDAP_14310	2.319e-265	831.0	COG1022@1|root,COG1022@2|Bacteria,2G5S9@200795|Chloroflexi	200795|Chloroflexi	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
CMS1_k127_782287_4	926550.CLDAP_14320	1.051e-114	374.0	COG0411@1|root,COG0411@2|Bacteria,2G5VI@200795|Chloroflexi	200795|Chloroflexi	E	PFAM ABC transporter related	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
CMS1_k127_782831_2	1227487.C474_17034	3.556e-18	88.0	COG0451@1|root,arCOG04704@2157|Archaea,2XUHT@28890|Euryarchaeota,23RXV@183963|Halobacteria	183963|Halobacteria	M	NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
CMS1_k127_782831_0	479434.Sthe_1490	2.061e-160	523.0	COG0488@1|root,COG0488@2|Bacteria,2G5VD@200795|Chloroflexi,27XQY@189775|Thermomicrobia	200795|Chloroflexi	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
CMS1_k127_782831_3	1348663.KCH_23180	2.274e-06	61.0	COG3227@1|root,COG3227@2|Bacteria,2IDQA@201174|Actinobacteria,2M09W@2063|Kitasatospora	201174|Actinobacteria	E	Putative Ig domain	-	-	-	-	-	-	-	-	-	-	-	-	FTP,He_PIG,PepSY,Peptidase_M4,Peptidase_M4_C
CMS1_k127_782831_1	298654.FraEuI1c_3163	3.963e-102	366.0	COG1361@1|root,COG3291@1|root,COG1361@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	DUF11,DUF4394,PKD,Peptidase_M8
CMS1_k127_79321_0	1121019.AUMN01000023_gene3451	2.098e-137	444.0	COG1063@1|root,COG1063@2|Bacteria,2GKC7@201174|Actinobacteria	201174|Actinobacteria	E	alcohol dehydrogenase	-	-	1.1.1.14,1.1.1.380	ko:K00008,ko:K08322	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896,R10848	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_79321_3	1033734.CAET01000006_gene3901	4.624e-71	248.0	COG0269@1|root,COG0269@2|Bacteria,1TQ55@1239|Firmicutes,4HBMT@91061|Bacilli,1ZBDI@1386|Bacillus	91061|Bacilli	G	3-hexulose-6-phosphate synthase	hxlA	GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.2.43	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	M00345,M00580	R05338	RC00421,RC00422	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
CMS1_k127_79321_1	383372.Rcas_1503	2.197e-125	416.0	COG0642@1|root,COG5000@1|root,COG2205@2|Bacteria,COG5000@2|Bacteria,2GBIC@200795|Chloroflexi,3780I@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
CMS1_k127_79321_2	765420.OSCT_0550	4.736e-98	324.0	COG0745@1|root,COG0745@2|Bacteria,2GBT3@200795|Chloroflexi,376HQ@32061|Chloroflexia	32061|Chloroflexia	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_79321_9	1476583.DEIPH_ctg001orf0045	3.552e-11	71.0	2E4CV@1|root,32Z89@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2680
CMS1_k127_79321_7	1140.Synpcc7942_1814	6.431e-26	117.0	COG0664@1|root,COG3850@1|root,COG0664@2|Bacteria,COG3850@2|Bacteria,1GEZE@1117|Cyanobacteria,1H27Y@1129|Synechococcus	1117|Cyanobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
CMS1_k127_79321_4	926569.ANT_18260	2.925e-60	214.0	COG0634@1|root,COG0634@2|Bacteria,2G6HX@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	GAF_2,Pribosyltran
CMS1_k127_79321_5	926569.ANT_18270	6.729e-43	160.0	COG1102@1|root,COG1102@2|Bacteria	2|Bacteria	F	Psort location Cytoplasmic, score	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Cytidylate_kin2,GAF_2,Pribosyltran
CMS1_k127_79321_6	926569.ANT_18280	7.532e-42	161.0	COG1102@1|root,COG1102@2|Bacteria	2|Bacteria	F	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
CMS1_k127_79321_8	926550.CLDAP_22510	3.363e-23	98.0	COG0488@1|root,COG0488@2|Bacteria	2|Bacteria	L	(ABC) transporter	yjjK	GO:0003674,GO:0003824,GO:0005488,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113	3.6.3.25	ko:K06020	-	-	-	-	ko00000,ko01000	-	-	-	ABC_tran,ABC_tran_Xtn
CMS1_k127_8070_3	489825.LYNGBM3L_13050	1.251e-158	505.0	COG4608@1|root,COG4608@2|Bacteria,1G1Q0@1117|Cyanobacteria,1HA59@1150|Oscillatoriales	1117|Cyanobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
CMS1_k127_8070_4	926550.CLDAP_11120	7.161e-157	500.0	COG0444@1|root,COG0444@2|Bacteria,2G61B@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
CMS1_k127_8070_10	1500257.JQNM01000001_gene4100	6.695e-76	265.0	COG1173@1|root,COG1173@2|Bacteria,1PAPF@1224|Proteobacteria,2TSUH@28211|Alphaproteobacteria,4BBYH@82115|Rhizobiaceae	28211|Alphaproteobacteria	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
CMS1_k127_8070_11	1121479.AUBS01000043_gene149	4.398e-64	230.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TRH6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components	MA20_32335	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_8070_5	765420.OSCT_1472	5.566e-128	430.0	COG4166@1|root,COG4166@2|Bacteria,2G5TA@200795|Chloroflexi,376RY@32061|Chloroflexia	32061|Chloroflexia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_8070_6	926550.CLDAP_02150	2.163e-124	411.0	COG0438@1|root,COG0438@2|Bacteria,2G67A@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
CMS1_k127_8070_8	479434.Sthe_0495	1.678e-104	354.0	COG0539@1|root,COG0539@2|Bacteria,2G656@200795|Chloroflexi,27XFV@189775|Thermomicrobia	189775|Thermomicrobia	J	Ribosomal protein S1-like RNA-binding domain	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
CMS1_k127_8070_0	926550.CLDAP_19360	0.0	1104.0	COG0542@1|root,COG0542@2|Bacteria,2G5RA@200795|Chloroflexi	200795|Chloroflexi	O	ATPase AAA-2 domain protein	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,HTH_17,UVR
CMS1_k127_8070_2	926550.CLDAP_11840	2.884e-167	538.0	COG1066@1|root,COG1066@2|Bacteria,2G5TE@200795|Chloroflexi	200795|Chloroflexi	L	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
CMS1_k127_8070_7	926569.ANT_30570	6.727e-109	363.0	COG4956@1|root,COG4956@2|Bacteria,2G5YK@200795|Chloroflexi	200795|Chloroflexi	S	SMART Nucleotide binding protein, PINc	-	-	-	-	-	-	-	-	-	-	-	-	TRAM
CMS1_k127_8070_1	247490.KSU1_D0522	1.355e-209	663.0	COG0215@1|root,COG0215@2|Bacteria,2IX9C@203682|Planctomycetes	203682|Planctomycetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
CMS1_k127_8070_9	765420.OSCT_0147	1.504e-78	269.0	COG0566@1|root,COG0566@2|Bacteria,2G6FR@200795|Chloroflexi,375AH@32061|Chloroflexia	32061|Chloroflexia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
CMS1_k127_8070_12	479434.Sthe_1611	1.667e-53	189.0	COG0050@1|root,COG0050@2|Bacteria,2G5KI@200795|Chloroflexi,27XXD@189775|Thermomicrobia	189775|Thermomicrobia	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	-	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
CMS1_k127_810771_2	926550.CLDAP_29830	1.537e-57	228.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Glucosaminidase,Peptidase_M23,Peptidase_M56,SLT
CMS1_k127_810771_4	670487.Ocepr_0156	1.392e-16	95.0	COG2730@1|root,COG2730@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	3.2.1.123,3.2.1.4	ko:K01179,ko:K05991	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase,Glyco_hydro_115,Glyco_hydro_67N
CMS1_k127_810771_0	269797.Mbar_A2862	5.687e-179	608.0	COG2319@1|root,arCOG02561@2157|Archaea,2Y41K@28890|Euryarchaeota,2NAYQ@224756|Methanomicrobia	224756|Methanomicrobia	S	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	WD40
CMS1_k127_810771_1	765420.OSCT_3186	9.84e-78	285.0	COG4995@1|root,COG4995@2|Bacteria,2G8YF@200795|Chloroflexi,377C0@32061|Chloroflexia	32061|Chloroflexia	P	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,SIR2_2
CMS1_k127_810771_3	179408.Osc7112_6105	1.408e-17	90.0	COG1366@1|root,COG1366@2|Bacteria,1G7NW@1117|Cyanobacteria,1HCQQ@1150|Oscillatoriales	1117|Cyanobacteria	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	-	-	-	-	-	-	-	-	-	STAS
CMS1_k127_861433_2	1082705.JIBP01000023_gene3141	0.0002932	45.0	COG2362@1|root,COG2362@2|Bacteria,1QH4F@1224|Proteobacteria,1RNPK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	peptidase M55 D-aminopeptidase	-	-	-	ko:K16203	-	-	-	-	ko00000,ko01000,ko01002	3.A.1.5.2	-	-	Peptidase_M55
CMS1_k127_861433_0	1232437.KL661985_gene3563	5.217e-155	506.0	COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,42RYP@68525|delta/epsilon subdivisions,2WNDE@28221|Deltaproteobacteria,2MK5X@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Amidase	-	-	3.5.1.4,3.5.1.99	ko:K01426,ko:K19176	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
CMS1_k127_861433_1	926554.KI912635_gene3019	1.346e-62	222.0	COG2258@1|root,COG2258@2|Bacteria,1WMGC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
CMS1_k127_889535_7	66875.JODY01000017_gene495	1.172e-30	136.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF11
CMS1_k127_889535_0	929556.Solca_3209	0.0	1691.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,4NFRF@976|Bacteroidetes,1IR6C@117747|Sphingobacteriia	976|Bacteroidetes	E	Methionine synthase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
CMS1_k127_889535_4	88036.EFJ15613	3.384e-67	235.0	COG0120@1|root,KOG3075@2759|Eukaryota,37IAG@33090|Viridiplantae,3G8FU@35493|Streptophyta	35493|Streptophyta	G	Ribose-5-phosphate isomerase	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006950,GO:0006952,GO:0008150,GO:0008152,GO:0009058,GO:0009507,GO:0009526,GO:0009532,GO:0009534,GO:0009535,GO:0009536,GO:0009570,GO:0009579,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009725,GO:0009735,GO:0009941,GO:0009987,GO:0010033,GO:0015977,GO:0015979,GO:0016020,GO:0016051,GO:0019253,GO:0019685,GO:0031967,GO:0031975,GO:0031976,GO:0031984,GO:0034357,GO:0042221,GO:0042651,GO:0042742,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0050896,GO:0051704,GO:0051707,GO:0055035,GO:0071704,GO:0098542,GO:1901576	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A
CMS1_k127_889535_9	411474.COPEUT_02526	6.571e-15	86.0	COG1266@1|root,COG1266@2|Bacteria,1VAFM@1239|Firmicutes,24DNF@186801|Clostridia	186801|Clostridia	S	CAAX amino terminal protease family protein	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
CMS1_k127_889535_5	1128421.JAGA01000001_gene2454	5.812e-50	186.0	COG0745@1|root,COG0745@2|Bacteria,2NQZN@2323|unclassified Bacteria	2|Bacteria	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_889535_8	479434.Sthe_2665	1.278e-27	131.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,2GA77@200795|Chloroflexi	200795|Chloroflexi	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_9
CMS1_k127_889535_6	765420.OSCT_2703	9.606e-36	157.0	COG0745@1|root,COG4191@1|root,COG0745@2|Bacteria,COG4191@2|Bacteria,2G7Y4@200795|Chloroflexi,374VX@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA,PAS_4,Response_reg
CMS1_k127_889535_1	357808.RoseRS_0178	6.941e-134	463.0	COG0577@1|root,COG0577@2|Bacteria,2G5WX@200795|Chloroflexi	200795|Chloroflexi	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
CMS1_k127_889535_10	525904.Tter_2712	1.467e-10	68.0	COG4283@1|root,COG4283@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1706)	M1-431	-	-	-	-	-	-	-	-	-	-	-	DUF1706
CMS1_k127_889535_12	243924.LT42_05370	5.504e-06	54.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1SMFA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_8,Response_reg
CMS1_k127_889535_11	926550.CLDAP_35070	2.73e-07	58.0	COG0784@1|root,COG2202@1|root,COG2203@1|root,COG3275@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3275@2|Bacteria,COG4191@2|Bacteria,2G7Y4@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	5TM-5TMR_LYT,GAF_2,HATPase_c,HisKA,HisKA_7TM,PAS,PAS_4,PAS_8,PAS_9,Response_reg
CMS1_k127_889535_2	1144319.PMI16_04926	2.1e-78	267.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,2VRBV@28216|Betaproteobacteria,478XB@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	ko:K14979	ko02020,map02020	M00663	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
CMS1_k127_889535_3	330214.NIDE3092	9.501e-70	257.0	COG2202@1|root,COG3829@1|root,COG4585@1|root,COG2202@2|Bacteria,COG3829@2|Bacteria,COG4585@2|Bacteria,3J12P@40117|Nitrospirae	40117|Nitrospirae	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,HATPase_c,HisKA_3,PAS_9
CMS1_k127_901263_5	105559.Nwat_2036	9.258e-28	124.0	COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,1SYQK@1236|Gammaproteobacteria,1X0BB@135613|Chromatiales	135613|Chromatiales	M	NmrA-like family	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
CMS1_k127_901263_0	926569.ANT_14670	1.593e-163	534.0	COG2414@1|root,COG2414@2|Bacteria,2G5XP@200795|Chloroflexi	200795|Chloroflexi	C	PFAM aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
CMS1_k127_901263_1	926569.ANT_14660	1.018e-131	432.0	COG1454@1|root,COG1454@2|Bacteria,2G6IU@200795|Chloroflexi	200795|Chloroflexi	C	PFAM iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
CMS1_k127_901263_4	926569.ANT_14650	3.195e-37	144.0	COG3255@1|root,COG3255@2|Bacteria,2G95B@200795|Chloroflexi	200795|Chloroflexi	I	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
CMS1_k127_901263_3	316274.Haur_4259	1.438e-58	228.0	COG0745@1|root,COG0784@1|root,COG2203@1|root,COG4191@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,2G7Y4@200795|Chloroflexi,374VX@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA,PAS_4,Response_reg
CMS1_k127_901263_2	765420.OSCT_2550	1.235e-61	220.0	COG0745@1|root,COG0745@2|Bacteria,2G6A5@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_901263_6	869210.Marky_0994	4.046e-16	78.0	COG2128@1|root,COG2128@2|Bacteria,1WJ8T@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Protein of unknown function (DUF3179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3179
CMS1_k127_901735_2	926550.CLDAP_19780	3.838e-147	470.0	COG0685@1|root,COG0685@2|Bacteria,2G7NU@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Methylenetetrahydrofolate reductase	-	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
CMS1_k127_901735_4	926550.CLDAP_32700	1.25e-107	353.0	COG5012@1|root,COG5012@2|Bacteria	2|Bacteria	T	cobalamin binding	mtbC	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2
CMS1_k127_901735_1	926550.CLDAP_32690	1.778e-300	934.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,2G7SW@200795|Chloroflexi	200795|Chloroflexi	C	Domain of unknown function (DUF4445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
CMS1_k127_901735_5	926550.CLDAP_19750	5.311e-29	118.0	COG5012@1|root,COG5012@2|Bacteria	2|Bacteria	T	cobalamin binding	-	-	-	-	-	-	-	-	-	-	-	-	Virulence_fact
CMS1_k127_901735_0	1541065.JRFE01000015_gene416	0.0	1032.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,1G0GR@1117|Cyanobacteria,3VI61@52604|Pleurocapsales	1117|Cyanobacteria	E	Glycine cleavage system T protein	-	-	1.5.3.1	ko:K00302	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	Fer2_4,GCV_T,GCV_T_C,Pyr_redox_2
CMS1_k127_901735_3	313624.NSP_51940	1.318e-114	379.0	COG5464@1|root,COG5464@2|Bacteria,1G2UF@1117|Cyanobacteria,1HKPY@1161|Nostocales	1117|Cyanobacteria	S	transposase or invertase	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_31
CMS1_k127_902328_5	485913.Krac_11786	5.743e-115	377.0	COG0249@1|root,COG0249@2|Bacteria,2G8CJ@200795|Chloroflexi	200795|Chloroflexi	L	PFAM DNA mismatch repair protein MutS domain protein	-	-	-	-	-	-	-	-	-	-	-	-	MutS_V
CMS1_k127_902328_14	525904.Tter_2599	8.264e-79	274.0	COG0451@1|root,COG0451@2|Bacteria,2NPZU@2323|unclassified Bacteria	2|Bacteria	M	Male sterility protein	-	-	1.1.1.219,5.1.3.26	ko:K00091,ko:K19997	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
CMS1_k127_902328_19	1382356.JQMP01000003_gene1459	4.774e-46	173.0	COG2096@1|root,COG2096@2|Bacteria,2G6TB@200795|Chloroflexi,27Y88@189775|Thermomicrobia	189775|Thermomicrobia	S	Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
CMS1_k127_902328_28	335283.Neut_2099	3.726e-10	66.0	COG4244@1|root,COG4244@2|Bacteria,1NJGN@1224|Proteobacteria,2VYSI@28216|Betaproteobacteria,37354@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Predicted membrane protein (DUF2231)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2231
CMS1_k127_902328_20	1122939.ATUD01000011_gene2304	3.029e-40	154.0	COG1528@1|root,COG1528@2|Bacteria,2IG5S@201174|Actinobacteria,4CU3R@84995|Rubrobacteria	84995|Rubrobacteria	P	Ferritin-like domain	-	-	1.16.3.1	ko:K22336	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
CMS1_k127_902328_15	118163.Ple7327_1594	2.675e-75	284.0	COG2203@1|root,COG3437@1|root,COG3452@1|root,COG5000@1|root,COG5002@1|root,COG2203@2|Bacteria,COG3437@2|Bacteria,COG3452@2|Bacteria,COG5000@2|Bacteria,COG5002@2|Bacteria,1FZYQ@1117|Cyanobacteria,3VIKA@52604|Pleurocapsales	1117|Cyanobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
CMS1_k127_902328_10	103690.17131278	6.343e-95	321.0	COG4759@1|root,COG4759@2|Bacteria,1G121@1117|Cyanobacteria,1HKJU@1161|Nostocales	1117|Cyanobacteria	O	PFAM Sucrase ferredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Suc_Fer-like
CMS1_k127_902328_18	479434.Sthe_1384	2.01e-51	190.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,2G6N4@200795|Chloroflexi,27YBV@189775|Thermomicrobia	189775|Thermomicrobia	K	FeoA	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
CMS1_k127_902328_30	670487.Ocepr_0856	4.239e-07	62.0	COG1652@1|root,COG1652@2|Bacteria	2|Bacteria	S	positive regulation of growth rate	-	-	-	-	-	-	-	-	-	-	-	-	LysM
CMS1_k127_902328_4	1128421.JAGA01000002_gene425	2.183e-125	415.0	COG1840@1|root,COG1840@2|Bacteria,2NPYA@2323|unclassified Bacteria	2|Bacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_1,SBP_bac_11,SBP_bac_6,SBP_bac_8
CMS1_k127_902328_1	266117.Rxyl_1174	3.953e-177	570.0	COG1178@1|root,COG1178@2|Bacteria,2GKPT@201174|Actinobacteria	201174|Actinobacteria	P	Binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
CMS1_k127_902328_7	326427.Cagg_2622	2.007e-104	349.0	COG3842@1|root,COG3842@2|Bacteria,2G5P8@200795|Chloroflexi,37556@32061|Chloroflexia	32061|Chloroflexia	P	Belongs to the ABC transporter superfamily	-	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
CMS1_k127_902328_16	765420.OSCT_3029	9.918e-71	259.0	COG0308@1|root,COG0308@2|Bacteria,2G75V@200795|Chloroflexi,375Q4@32061|Chloroflexia	32061|Chloroflexia	M	PFAM peptidase M1, membrane alanine aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
CMS1_k127_902328_26	1303692.SFUL_4880	4.989e-16	93.0	COG0457@1|root,COG0457@2|Bacteria,2IGEN@201174|Actinobacteria	201174|Actinobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TIR_2,TPR_12
CMS1_k127_902328_22	1203568.HMPREF1484_01540	7.735e-31	130.0	COG1555@1|root,COG1555@2|Bacteria,2IQDC@201174|Actinobacteria,4FCVN@85020|Dermabacteraceae	201174|Actinobacteria	L	SLBB domain	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
CMS1_k127_902328_11	926569.ANT_22600	2.561e-93	318.0	COG2348@1|root,COG2348@2|Bacteria,2G6KK@200795|Chloroflexi	200795|Chloroflexi	V	PFAM Methicillin resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	FemAB
CMS1_k127_902328_12	926569.ANT_22610	1.482e-83	288.0	COG2348@1|root,COG2348@2|Bacteria,2G6KK@200795|Chloroflexi	200795|Chloroflexi	V	PFAM Methicillin resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	FemAB
CMS1_k127_902328_21	316274.Haur_4980	1.302e-33	133.0	COG0838@1|root,COG0838@2|Bacteria,2G71E@200795|Chloroflexi,375NS@32061|Chloroflexia	32061|Chloroflexia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
CMS1_k127_902328_8	926569.ANT_10420	1.511e-99	338.0	COG1005@1|root,COG1005@2|Bacteria,2G60S@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
CMS1_k127_902328_24	316274.Haur_4986	2.46e-22	103.0	COG0839@1|root,COG0839@2|Bacteria,2G777@200795|Chloroflexi,375K1@32061|Chloroflexia	32061|Chloroflexia	C	Belongs to the complex I subunit 6 family	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
CMS1_k127_902328_23	383372.Rcas_2095	1.801e-29	120.0	COG0713@1|root,COG0713@2|Bacteria,2G782@200795|Chloroflexi,375VH@32061|Chloroflexia	32061|Chloroflexia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
CMS1_k127_902328_3	1382304.JNIL01000001_gene2381	4.942e-137	460.0	COG1009@1|root,COG1009@2|Bacteria,1TQW4@1239|Firmicutes,4H9YR@91061|Bacilli,27873@186823|Alicyclobacillaceae	91061|Bacilli	CP	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
CMS1_k127_902328_2	926550.CLDAP_08830	1.465e-156	510.0	COG1008@1|root,COG1008@2|Bacteria,2G5VU@200795|Chloroflexi	200795|Chloroflexi	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
CMS1_k127_902328_6	926550.CLDAP_08840	1.517e-104	358.0	COG1007@1|root,COG1007@2|Bacteria,2G5ZK@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
CMS1_k127_902328_29	2045.KR76_09265	1.096e-07	66.0	COG3087@1|root,COG3087@2|Bacteria,2GNX9@201174|Actinobacteria,4DQMG@85009|Propionibacteriales	201174|Actinobacteria	D	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_902328_9	671143.DAMO_1521	7.759e-98	324.0	COG0569@1|root,COG0569@2|Bacteria,2NPN3@2323|unclassified Bacteria	2|Bacteria	P	TrkA-C domain	trkA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
CMS1_k127_902328_13	671143.DAMO_1520	2.788e-83	284.0	COG0569@1|root,COG0569@2|Bacteria,2NPXT@2323|unclassified Bacteria	2|Bacteria	P	TrkA-N domain	ceoB	-	-	ko:K03499,ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6,2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
CMS1_k127_902328_0	671143.DAMO_0407	1.857e-314	974.0	COG0531@1|root,COG0531@2|Bacteria,2NNZQ@2323|unclassified Bacteria	2|Bacteria	E	Amino acid permease	ydaO	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039	-	-	-	-	-	-	-	-	-	-	AA_permease_2
CMS1_k127_902328_27	1304284.L21TH_1999	1.638e-15	89.0	COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,248FS@186801|Clostridia,36EAC@31979|Clostridiaceae	186801|Clostridia	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
CMS1_k127_902328_17	1246995.AFR_14815	1.228e-56	216.0	COG3291@1|root,COG3291@2|Bacteria,2H3GB@201174|Actinobacteria	201174|Actinobacteria	S	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	PKD
CMS1_k127_902328_25	926550.CLDAP_30620	3.322e-19	102.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Inhibitor_I9,Peptidase_S8,TIG
CMS1_k127_905248_1	926550.CLDAP_05000	4.135e-102	345.0	COG0046@1|root,COG1828@1|root,COG0046@2|Bacteria,COG1828@2|Bacteria,2G5Z1@200795|Chloroflexi	200795|Chloroflexi	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,PurS
CMS1_k127_905248_0	401526.TcarDRAFT_0254	5.084e-192	610.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,4H2GU@909932|Negativicutes	909932|Negativicutes	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
CMS1_k127_905248_3	1304878.AUGD01000001_gene289	2.674e-65	236.0	COG2055@1|root,COG2055@2|Bacteria,1MWQY@1224|Proteobacteria,2TR37@28211|Alphaproteobacteria,3JVES@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Malate/L-lactate dehydrogenase	MA20_06110	-	1.1.1.350	ko:K00073,ko:K13574	ko00230,ko01120,map00230,map01120	-	R02935,R02936	RC00169	ko00000,ko00001,ko01000	-	-	-	Ldh_2
CMS1_k127_905248_2	479434.Sthe_0255	2.761e-74	261.0	COG1250@1|root,COG1250@2|Bacteria,2G6EB@200795|Chloroflexi	2|Bacteria	C	3-hydroxyacyl-CoA dehydrogenase domain protein	fadB3	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
CMS1_k127_905248_4	765420.OSCT_1375	1.688e-33	146.0	COG4995@1|root,COG4995@2|Bacteria,2G8YF@200795|Chloroflexi	200795|Chloroflexi	P	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	SIR2_2
CMS1_k127_905248_5	102129.Lepto7375DRAFT_7471	2.717e-06	60.0	COG0775@1|root,COG1262@1|root,COG5635@1|root,COG0775@2|Bacteria,COG1262@2|Bacteria,COG5635@2|Bacteria	2|Bacteria	T	Nacht domain	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,HEAT_2,HEAT_PBS,NACHT,PNP_UDP_1
CMS1_k127_908527_6	1122207.MUS1_15200	6.125e-83	288.0	COG1482@1|root,COG1482@2|Bacteria,1QE1E@1224|Proteobacteria,1RZ8T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	cell wall glycoprotein biosynthetic process	manA	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	-
CMS1_k127_908527_0	926550.CLDAP_31970	0.0	1477.0	COG0383@1|root,COG0383@2|Bacteria,2G5U7@200795|Chloroflexi	200795|Chloroflexi	G	glycosyl hydrolase 38 domain protein	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
CMS1_k127_908527_9	926569.ANT_05130	0.0001023	55.0	COG3206@1|root,COG3206@2|Bacteria	2|Bacteria	M	extracellular polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Wzz
CMS1_k127_908527_8	797515.HMPREF9103_02557	3.44e-05	56.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli,3F4G6@33958|Lactobacillaceae	91061|Bacilli	KLT	serine threonine protein kinase	prkC	GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
CMS1_k127_908527_7	640081.Dsui_1522	6.345e-08	65.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria,2KV51@206389|Rhodocyclales	28216|Betaproteobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
CMS1_k127_908527_4	926550.CLDAP_31950	3.052e-148	478.0	COG4608@1|root,COG4608@2|Bacteria,2G6CB@200795|Chloroflexi	200795|Chloroflexi	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,oligo_HPY
CMS1_k127_908527_3	926550.CLDAP_31920	3.705e-154	493.0	COG0444@1|root,COG0444@2|Bacteria,2G61F@200795|Chloroflexi	200795|Chloroflexi	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
CMS1_k127_908527_5	926550.CLDAP_31910	7.737e-120	392.0	COG1173@1|root,COG1173@2|Bacteria	2|Bacteria	P	ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
CMS1_k127_908527_2	926550.CLDAP_31900	1.575e-154	494.0	COG0601@1|root,COG0601@2|Bacteria,2G6RM@200795|Chloroflexi	200795|Chloroflexi	P	COGs COG0601 ABC-type dipeptide oligopeptide nickel transport systems permease components	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_908527_1	926550.CLDAP_31890	2.477e-266	832.0	COG0747@1|root,COG0747@2|Bacteria,2G89C@200795|Chloroflexi	200795|Chloroflexi	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_910829_3	1454010.JEOE01000004_gene42	8.79e-40	151.0	28VK2@1|root,2ZHNE@2|Bacteria,2IBCS@201174|Actinobacteria	201174|Actinobacteria	S	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
CMS1_k127_910829_6	1122182.KB903815_gene1460	1.138e-07	64.0	COG1653@1|root,COG1653@2|Bacteria,2GJSR@201174|Actinobacteria,4DCVG@85008|Micromonosporales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
CMS1_k127_910829_1	521045.Kole_0692	4.123e-65	235.0	COG1175@1|root,COG1175@2|Bacteria,2GC8J@200918|Thermotogae	200918|Thermotogae	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025,ko:K17242	ko02010,map02010	M00207,M00600	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.39	-	-	BPD_transp_1
CMS1_k127_910829_0	373903.Hore_20610	1.976e-66	237.0	COG0395@1|root,COG0395@2|Bacteria,1TRCP@1239|Firmicutes,25C50@186801|Clostridia,3WCAF@53433|Halanaerobiales	186801|Clostridia	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_910829_2	1033743.CAES01000007_gene2053	4.845e-53	195.0	COG5285@1|root,COG5285@2|Bacteria,1V19S@1239|Firmicutes,4HEC1@91061|Bacilli,26RNZ@186822|Paenibacillaceae	91061|Bacilli	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
CMS1_k127_910829_4	383372.Rcas_2255	1.472e-30	136.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_911612_3	526227.Mesil_0667	2.148e-24	106.0	COG1063@1|root,COG1063@2|Bacteria	2|Bacteria	E	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_911612_2	1173264.KI913949_gene3115	3.214e-29	119.0	2E5P1@1|root,330DP@2|Bacteria,1G9FB@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
CMS1_k127_911612_1	926550.CLDAP_34490	1.655e-122	399.0	COG1210@1|root,COG1210@2|Bacteria,2G6XV@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Nucleotidyl transferase	-	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
CMS1_k127_911612_0	926550.CLDAP_27180	0.0	1338.0	COG4284@1|root,COG4284@2|Bacteria	2|Bacteria	G	Utp--glucose-1-phosphate uridylyltransferase	-	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPGP
CMS1_k127_913451_3	1121405.dsmv_1874	2.717e-89	299.0	COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,42MY7@68525|delta/epsilon subdivisions,2WJH7@28221|Deltaproteobacteria,2MIBN@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1988	QRPTase_C,QRPTase_N
CMS1_k127_913451_2	357808.RoseRS_0438	4.851e-172	548.0	COG0379@1|root,COG0379@2|Bacteria,2G64Y@200795|Chloroflexi,375TJ@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
CMS1_k127_913451_0	1121405.dsmv_1872	1.518e-204	648.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,43BKD@68525|delta/epsilon subdivisions,2WJNK@28221|Deltaproteobacteria,2MIMB@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
CMS1_k127_913451_5	1128421.JAGA01000001_gene2108	5.417e-60	212.0	COG1827@1|root,COG1827@2|Bacteria,2NR9J@2323|unclassified Bacteria	2|Bacteria	S	3H domain	niaR	-	-	ko:K07105	-	-	-	-	ko00000	-	-	-	3H,HTH_11
CMS1_k127_913451_4	926550.CLDAP_20570	3.931e-78	268.0	COG3634@1|root,COG3634@2|Bacteria,2G6SQ@200795|Chloroflexi	200795|Chloroflexi	O	TIGRFAM glutaredoxin-like domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
CMS1_k127_913451_7	926550.CLDAP_28250	2.369e-41	156.0	COG3439@1|root,COG3439@2|Bacteria,2G72I@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
CMS1_k127_913451_1	867845.KI911784_gene3494	1.574e-182	581.0	COG0446@1|root,COG0446@2|Bacteria,2G68U@200795|Chloroflexi,3771J@32061|Chloroflexia	32061|Chloroflexia	P	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
CMS1_k127_913451_10	1424334.W822_13735	9.381e-07	53.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,2VSHX@28216|Betaproteobacteria,3T488@506|Alcaligenaceae	28216|Betaproteobacteria	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
CMS1_k127_913451_6	926550.CLDAP_20580	9.624e-49	181.0	COG1595@1|root,COG1595@2|Bacteria,2G6PJ@200795|Chloroflexi	200795|Chloroflexi	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
CMS1_k127_913451_8	926550.CLDAP_20590	8.195e-20	91.0	COG5660@1|root,COG5660@2|Bacteria,2G7CH@200795|Chloroflexi	200795|Chloroflexi	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
CMS1_k127_914500_2	555088.DealDRAFT_0819	1.691e-08	59.0	COG2273@1|root,COG5337@1|root,COG2273@2|Bacteria,COG5337@2|Bacteria,1TRAW@1239|Firmicutes,24AQY@186801|Clostridia	186801|Clostridia	M	PFAM Spore coat protein CotH	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,Dockerin_1,Fn3_assoc,LTD
CMS1_k127_914500_1	880072.Desac_2131	2.904e-20	105.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,42PHP@68525|delta/epsilon subdivisions,2WIXN@28221|Deltaproteobacteria,2MQDX@213462|Syntrophobacterales	28221|Deltaproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
CMS1_k127_914500_0	332101.JIBU02000020_gene2066	1.775e-28	121.0	COG1595@1|root,COG1595@2|Bacteria,1V4E2@1239|Firmicutes,24GZP@186801|Clostridia,36HYP@31979|Clostridiaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS1_k127_915906_2	1380356.JNIK01000015_gene2406	3.284e-100	340.0	COG2120@1|root,COG2120@2|Bacteria,2IBQH@201174|Actinobacteria	201174|Actinobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
CMS1_k127_915906_5	485913.Krac_5264	4.194e-25	115.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7,Acetyltransf_9
CMS1_k127_915906_3	1237149.C900_05711	3.515e-67	240.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS1_k127_915906_0	1128421.JAGA01000003_gene3678	2.043e-183	614.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2NQCZ@2323|unclassified Bacteria	2|Bacteria	K	NB-ARC domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_22,BTAD,NB-ARC,TPR_10,TPR_12,TPR_8,Trans_reg_C
CMS1_k127_915906_1	1385935.N836_32270	1.196e-144	468.0	COG2230@1|root,COG2230@2|Bacteria,1G3TN@1117|Cyanobacteria,1H8KG@1150|Oscillatoriales	1117|Cyanobacteria	M	Methylase involved in ubiquinone menaquinone biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
CMS1_k127_915906_4	102129.Lepto7375DRAFT_7836	2.394e-38	151.0	2A53S@1|root,30TSD@2|Bacteria,1GGW0@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_915906_6	324602.Caur_3141	8.38e-20	96.0	COG2909@1|root,COG2909@2|Bacteria	2|Bacteria	K	trisaccharide binding	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,GerE,NACHT,TPR_12
CMS1_k127_916418_1	926550.CLDAP_24950	4.739e-70	257.0	COG0457@1|root,COG1846@1|root,COG0457@2|Bacteria,COG1846@2|Bacteria,2G9ET@200795|Chloroflexi	200795|Chloroflexi	NU	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
CMS1_k127_916418_5	1123368.AUIS01000030_gene1253	5.789e-32	127.0	COG1522@1|root,COG1522@2|Bacteria,1NC1H@1224|Proteobacteria,1SE9N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
CMS1_k127_916418_6	321332.CYB_0562	8.867e-23	115.0	COG2385@1|root,COG2385@2|Bacteria,1G0XG@1117|Cyanobacteria,1H0F9@1129|Synechococcus	1117|Cyanobacteria	D	COG2385 Sporulation protein and related proteins	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
CMS1_k127_916418_3	880073.Calab_3338	1.595e-56	210.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Trypsin,Trypsin_2
CMS1_k127_916418_0	926569.ANT_00850	1.181e-218	686.0	COG1350@1|root,COG1350@2|Bacteria,2G5YY@200795|Chloroflexi	200795|Chloroflexi	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS1_k127_916418_11	1210884.HG799476_gene15392	0.0001479	46.0	COG3483@1|root,COG3483@2|Bacteria,2J412@203682|Planctomycetes	203682|Planctomycetes	E	Tryptophan 2,3-dioxygenase	-	-	1.13.11.11	ko:K00453	ko00380,ko01100,map00380,map01100	M00038	R00678	RC00356	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_dioxygenase
CMS1_k127_916418_8	1444309.JAQG01000003_gene4439	2.274e-07	64.0	COG0840@1|root,COG0840@2|Bacteria,1V4DX@1239|Firmicutes,4IQFE@91061|Bacilli,26SEV@186822|Paenibacillaceae	91061|Bacilli	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,MCPsignal
CMS1_k127_916418_4	309801.trd_1552	6.566e-41	171.0	COG3850@1|root,COG3850@2|Bacteria,2GBH4@200795|Chloroflexi,27XF0@189775|Thermomicrobia	189775|Thermomicrobia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
CMS1_k127_916418_2	1449126.JQKL01000042_gene1033	2.433e-66	233.0	COG2197@1|root,COG2197@2|Bacteria,1TRXG@1239|Firmicutes,24FZX@186801|Clostridia,269AP@186813|unclassified Clostridiales	186801|Clostridia	T	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS1_k127_91807_8	926569.ANT_23380	1.009e-89	309.0	COG0707@1|root,COG0707@2|Bacteria,2G6EH@200795|Chloroflexi	200795|Chloroflexi	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
CMS1_k127_91807_6	1382306.JNIM01000001_gene36	1.131e-97	332.0	COG0772@1|root,COG0772@2|Bacteria,2G5MQ@200795|Chloroflexi	200795|Chloroflexi	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
CMS1_k127_91807_4	926550.CLDAP_38120	5.673e-103	351.0	COG0771@1|root,COG0771@2|Bacteria,2G5VE@200795|Chloroflexi	200795|Chloroflexi	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
CMS1_k127_91807_3	926569.ANT_23350	1.756e-104	348.0	COG0472@1|root,COG0472@2|Bacteria,2G5TJ@200795|Chloroflexi	200795|Chloroflexi	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
CMS1_k127_91807_1	926569.ANT_23340	3.82e-144	471.0	COG0770@1|root,COG0770@2|Bacteria,2G5PN@200795|Chloroflexi	200795|Chloroflexi	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS1_k127_91807_2	525904.Tter_1614	7.915e-129	431.0	COG0768@1|root,COG0768@2|Bacteria,2NNWR@2323|unclassified Bacteria	2|Bacteria	M	Penicillin-binding Protein dimerisation domain	ftsI	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681	3.4.16.4	ko:K03587,ko:K08384	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	iSSON_1240.SSON_0092	PASTA,PBP_dimer,Transpeptidase
CMS1_k127_91807_5	926550.CLDAP_38170	3.381e-99	333.0	COG0275@1|root,COG0275@2|Bacteria,2G658@200795|Chloroflexi	200795|Chloroflexi	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
CMS1_k127_91807_9	1121864.OMO_01045	5.369e-43	161.0	COG2001@1|root,COG2001@2|Bacteria,1V3JD@1239|Firmicutes,4HH23@91061|Bacilli,4B2CD@81852|Enterococcaceae	91061|Bacilli	K	Belongs to the MraZ family	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
CMS1_k127_91807_7	324602.Caur_2686	3.568e-90	308.0	COG1089@1|root,COG1089@2|Bacteria,2G6AN@200795|Chloroflexi,3755V@32061|Chloroflexia	32061|Chloroflexia	M	PFAM NAD-dependent epimerase dehydratase	-	-	1.1.1.281	ko:K15856	ko00051,ko00520,map00051,map00520	-	R03397,R03399	RC00182	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
CMS1_k127_91807_0	926550.CLDAP_05850	2.886e-167	529.0	COG1089@1|root,COG1089@2|Bacteria,2G5P2@200795|Chloroflexi	200795|Chloroflexi	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
CMS1_k127_91807_10	1220534.B655_1079	1.614e-40	155.0	COG3503@1|root,arCOG04370@2157|Archaea,2XWYK@28890|Euryarchaeota	28890|Euryarchaeota	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
CMS1_k127_918669_9	926550.CLDAP_18190	1.351e-27	112.0	COG1146@1|root,COG1146@2|Bacteria,2G75G@200795|Chloroflexi	200795|Chloroflexi	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4
CMS1_k127_918669_8	1216967.L100_13949	7.617e-29	123.0	COG0454@1|root,COG0456@2|Bacteria,4NUQU@976|Bacteroidetes,1I53H@117743|Flavobacteriia,34RR0@308865|Elizabethkingia	976|Bacteroidetes	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
CMS1_k127_918669_0	357808.RoseRS_3864	1.132e-143	466.0	COG3616@1|root,COG3616@2|Bacteria,2G69D@200795|Chloroflexi	200795|Chloroflexi	E	PFAM alanine racemase domain protein	-	-	4.3.1.27	ko:K20757	-	-	-	-	ko00000,ko01000	-	-	-	Ala_racemase_N,D-ser_dehydrat
CMS1_k127_918669_4	2002.JOEQ01000006_gene1443	3.671e-68	239.0	COG0500@1|root,COG2226@2|Bacteria,2IBY2@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS1_k127_918669_2	926569.ANT_02760	1.217e-95	327.0	COG3173@1|root,COG3173@2|Bacteria	2|Bacteria	S	very-long-chain-acyl-CoA dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	APH
CMS1_k127_918669_11	1210045.ALNP01000027_gene786	0.0001484	47.0	COG0399@1|root,COG0399@2|Bacteria,2GKD7@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the DegT DnrJ EryC1 family	stsC	-	2.6.1.50	ko:K05957	ko00521,ko01130,map00521,map01130	-	R02781	RC00006,RC00781	ko00000,ko00001,ko01000,ko01007	-	-	-	DegT_DnrJ_EryC1
CMS1_k127_918669_6	66692.ABC3774	3.912e-46	184.0	COG1653@1|root,COG1653@2|Bacteria,1VSBH@1239|Firmicutes,4HTU3@91061|Bacilli,1ZEGS@1386|Bacillus	91061|Bacilli	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_8
CMS1_k127_918669_7	1123248.KB893359_gene2154	1.188e-39	157.0	COG0726@1|root,COG0726@2|Bacteria,4NJK7@976|Bacteroidetes	976|Bacteroidetes	G	PFAM Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
CMS1_k127_918669_1	525904.Tter_2523	2.099e-109	364.0	COG1175@1|root,COG1175@2|Bacteria,2NQCB@2323|unclassified Bacteria	2|Bacteria	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025,ko:K05814,ko:K10118,ko:K10237,ko:K10241,ko:K15771,ko:K17235,ko:K17316	ko02010,map02010	M00196,M00198,M00204,M00206,M00207,M00491,M00602,M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.17,3.A.1.1.2,3.A.1.1.23,3.A.1.1.24,3.A.1.1.28,3.A.1.1.3,3.A.1.1.30,3.A.1.1.34	-	-	BPD_transp_1
CMS1_k127_918669_3	525904.Tter_2216	2.086e-88	301.0	COG0395@1|root,COG0395@2|Bacteria,2NPII@2323|unclassified Bacteria	2|Bacteria	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02026,ko:K05815	ko02010,map02010	M00198,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.3	-	-	BPD_transp_1
CMS1_k127_918669_5	1035308.AQYY01000001_gene2876	5.907e-63	228.0	COG3315@1|root,COG3315@2|Bacteria,1UPJI@1239|Firmicutes,24BUU@186801|Clostridia,261X6@186807|Peptococcaceae	186801|Clostridia	Q	Leucine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	LCM
CMS1_k127_925574_0	1173026.Glo7428_2548	1.686e-194	626.0	COG2202@1|root,COG5001@1|root,COG5002@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,COG5002@2|Bacteria,1G0SY@1117|Cyanobacteria	1117|Cyanobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,PAS_3,PAS_9
CMS1_k127_925574_1	335543.Sfum_3112	4.261e-141	480.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42M1R@68525|delta/epsilon subdivisions,2WK3J@28221|Deltaproteobacteria,2MSIC@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
CMS1_k127_925574_2	243924.LT42_10545	3.116e-27	115.0	COG1679@1|root,COG1786@1|root,COG1679@2|Bacteria,COG1786@2|Bacteria,1NFH4@1224|Proteobacteria,1S4TW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF521)	-	-	-	ko:K09123	-	-	-	-	ko00000	-	-	-	DUF126,DUF521
CMS1_k127_927859_2	290399.Arth_1858	9.744e-33	128.0	COG2303@1|root,COG2303@2|Bacteria,2I5YA@201174|Actinobacteria	201174|Actinobacteria	E	oxidoreductase	-	-	1.1.99.3	ko:K06151	ko00030,ko01100,ko01120,map00030,map01100,map01120	-	R01741	RC00084	ko00000,ko00001,ko01000	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N,Gluconate_2-dh3,NAD_binding_8
CMS1_k127_927859_1	391735.Veis_3571	8.734e-79	271.0	COG1024@1|root,COG1024@2|Bacteria,1MWXK@1224|Proteobacteria	1224|Proteobacteria	I	enoyl-CoA hydratase	-	GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0043956	-	-	-	-	-	-	-	-	-	-	ECH_1
CMS1_k127_927859_5	869210.Marky_1098	2.816e-09	68.0	COG1082@1|root,COG1082@2|Bacteria,1WKRX@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Xylose isomerase domain protein TIM barrel	-	-	5.1.3.30,5.1.3.31	ko:K18910	-	-	R10817,R10818	RC03111,RC03283	ko00000,ko01000	-	-	-	AP_endonuc_2
CMS1_k127_927859_3	476272.RUMHYD_01689	3.709e-23	111.0	COG0673@1|root,COG0673@2|Bacteria,1TQ72@1239|Firmicutes,25KD4@186801|Clostridia,3Y1KW@572511|Blautia	186801|Clostridia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_927859_4	525897.Dbac_1575	1.334e-22	100.0	COG1359@1|root,COG1359@2|Bacteria,1RI7W@1224|Proteobacteria,42Y4G@68525|delta/epsilon subdivisions,2WTC4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
CMS1_k127_927859_0	1457250.BBMO01000001_gene224	1.399e-107	373.0	arCOG06227@1|root,arCOG06227@2157|Archaea,2XVPI@28890|Euryarchaeota,23UUI@183963|Halobacteria	183963|Halobacteria	S	Domain of unknown function (DUF4397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4397
CMS1_k127_9289_3	1128421.JAGA01000003_gene3003	9.322e-70	241.0	COG1089@1|root,COG1089@2|Bacteria,2NNM2@2323|unclassified Bacteria	2|Bacteria	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
CMS1_k127_9289_1	525904.Tter_1925	7.092e-83	287.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_9289_5	1120972.AUMH01000018_gene1948	4.375e-21	103.0	COG1082@1|root,COG1082@2|Bacteria,1V2HT@1239|Firmicutes,4HFBJ@91061|Bacilli	91061|Bacilli	G	Xylulose 5-phosphate 3-epimerase	-	-	5.1.3.22	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R03244	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	AP_endonuc_2
CMS1_k127_9289_2	525904.Tter_2317	2.085e-82	283.0	COG0395@1|root,COG0395@2|Bacteria	2|Bacteria	P	glycerophosphodiester transmembrane transport	-	-	-	ko:K02026,ko:K05815	ko02010,map02010	M00198,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.3	-	-	BPD_transp_1
CMS1_k127_9289_0	525904.Tter_2523	4.53e-98	330.0	COG1175@1|root,COG1175@2|Bacteria,2NQCB@2323|unclassified Bacteria	2|Bacteria	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025,ko:K05814,ko:K10118,ko:K10237,ko:K10241,ko:K15771,ko:K17235,ko:K17316	ko02010,map02010	M00196,M00198,M00204,M00206,M00207,M00491,M00602,M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.17,3.A.1.1.2,3.A.1.1.23,3.A.1.1.24,3.A.1.1.28,3.A.1.1.3,3.A.1.1.30,3.A.1.1.34	-	-	BPD_transp_1
CMS1_k127_9289_4	670487.Ocepr_0409	8.956e-23	111.0	COG1653@1|root,COG1653@2|Bacteria,1WJIN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1
CMS1_k127_936120_1	926569.ANT_02330	5.193e-95	319.0	COG0842@1|root,COG0842@2|Bacteria,2G5UH@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
CMS1_k127_936120_0	485913.Krac_11103	5.101e-123	402.0	COG0451@1|root,COG0451@2|Bacteria,2G9SG@200795|Chloroflexi	200795|Chloroflexi	GM	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
CMS1_k127_936120_3	1142394.PSMK_21300	1.037e-19	97.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS1_k127_936120_2	1122915.AUGY01000051_gene1306	1.353e-30	132.0	COG0667@1|root,COG0667@2|Bacteria,1TTT8@1239|Firmicutes,4H9XM@91061|Bacilli,26UF9@186822|Paenibacillaceae	91061|Bacilli	C	Oxidoreductase	yqkF	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS1_k127_936120_4	1239962.C943_03877	1.482e-18	99.0	COG0823@1|root,COG0823@2|Bacteria,4NEPF@976|Bacteroidetes,47NVJ@768503|Cytophagia	976|Bacteroidetes	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	CarbopepD_reg_2,CarboxypepD_reg,PD40
CMS1_k127_936120_5	383372.Rcas_2249	2.034e-12	71.0	COG3411@1|root,COG3411@2|Bacteria,2G8UE@200795|Chloroflexi	200795|Chloroflexi	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_938236_2	525904.Tter_1802	1.975e-127	417.0	COG0444@1|root,COG0444@2|Bacteria,2NQJ7@2323|unclassified Bacteria	2|Bacteria	P	Oligopeptide/dipeptide transporter, C-terminal region	oppD	-	-	ko:K02031,ko:K02032,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
CMS1_k127_938236_0	383372.Rcas_2452	1.172e-166	536.0	COG1173@1|root,COG1173@2|Bacteria,2G7U9@200795|Chloroflexi,377XX@32061|Chloroflexia	32061|Chloroflexia	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
CMS1_k127_938236_1	383372.Rcas_2453	8.916e-151	482.0	COG0601@1|root,COG0601@2|Bacteria,2G7WN@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_938236_3	383372.Rcas_2454	3.577e-38	144.0	COG0747@1|root,COG0747@2|Bacteria,2G84E@200795|Chloroflexi	200795|Chloroflexi	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_943008_4	1122919.KB905617_gene161	2.621e-63	226.0	COG3119@1|root,COG3119@2|Bacteria,1UDRD@1239|Firmicutes,4HD9J@91061|Bacilli,26WKF@186822|Paenibacillaceae	91061|Bacilli	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
CMS1_k127_943008_1	1123075.AUDP01000042_gene304	1.48e-122	412.0	COG3119@1|root,COG3119@2|Bacteria,1TSHE@1239|Firmicutes,24YJN@186801|Clostridia	186801|Clostridia	P	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
CMS1_k127_943008_0	1122132.AQYH01000006_gene3455	1.419e-183	580.0	COG4948@1|root,COG4948@2|Bacteria,1MURK@1224|Proteobacteria,2U0BF@28211|Alphaproteobacteria,4BBCF@82115|Rhizobiaceae	28211|Alphaproteobacteria	M	Mandelate racemase muconate	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
CMS1_k127_943008_3	344747.PM8797T_11626	4.25e-119	398.0	2EZBQ@1|root,33SH2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_943008_6	926569.ANT_26720	2.774e-17	87.0	COG5637@1|root,COG5637@2|Bacteria,2G9J4@200795|Chloroflexi	200795|Chloroflexi	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
CMS1_k127_943008_2	1122919.KB905548_gene2346	1.165e-120	396.0	COG1063@1|root,COG1063@2|Bacteria,1TS6I@1239|Firmicutes,4HBDT@91061|Bacilli,26T81@186822|Paenibacillaceae	91061|Bacilli	E	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_943008_5	324602.Caur_2690	1.941e-22	102.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Usp
CMS1_k127_943008_7	525904.Tter_2547	1.474e-16	84.0	COG0589@1|root,COG0589@2|Bacteria,2NRGN@2323|unclassified Bacteria	2|Bacteria	T	PFAM UspA domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS1_k127_946839_0	880073.Calab_1754	2.179e-86	306.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,2NQ6Y@2323|unclassified Bacteria	2|Bacteria	M	PKD domain	-	-	3.2.1.4,3.4.21.66	ko:K01179,ko:K08651	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	GH5,GH9	-	Autotransporter,PKD,Peptidase_S8,Peptidase_S8_N,fn3
CMS1_k127_948193_11	742743.HMPREF9453_01933	5.643e-08	64.0	COG2385@1|root,COG2385@2|Bacteria,1UW6J@1239|Firmicutes,4H227@909932|Negativicutes	909932|Negativicutes	D	SpoIID LytB domain protein	spoIID	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
CMS1_k127_948193_12	391625.PPSIR1_31363	5.427e-07	61.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,42PHP@68525|delta/epsilon subdivisions,2WIXN@28221|Deltaproteobacteria,2YU93@29|Myxococcales	28221|Deltaproteobacteria	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
CMS1_k127_948193_1	1382306.JNIM01000001_gene2770	1.416e-84	301.0	COG1840@1|root,COG2304@1|root,COG1840@2|Bacteria,COG2304@2|Bacteria,2G7PB@200795|Chloroflexi	200795|Chloroflexi	P	PFAM von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	SBP_bac_11,VWA
CMS1_k127_948193_8	502025.Hoch_5086	2.189e-12	80.0	COG0715@1|root,COG2885@1|root,COG0715@2|Bacteria,COG2885@2|Bacteria,1R687@1224|Proteobacteria,42ZCB@68525|delta/epsilon subdivisions,2WTSU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	MP	NMT1/THI5 like	-	-	-	-	-	-	-	-	-	-	-	-	NMT1,OmpA
CMS1_k127_948193_0	867845.KI911784_gene1126	3.918e-101	346.0	COG0019@1|root,COG0019@2|Bacteria,2GA9U@200795|Chloroflexi,3750K@32061|Chloroflexia	32061|Chloroflexia	E	PFAM Orn DAP Arg decarboxylase 2	-	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N
CMS1_k127_948193_2	357808.RoseRS_2308	1.336e-65	239.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2G719@200795|Chloroflexi,377PJ@32061|Chloroflexia	32061|Chloroflexia	S	Belongs to the peptidase M50B family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50
CMS1_k127_948193_10	1299327.I546_0627	1.715e-08	64.0	COG3012@1|root,COG3012@2|Bacteria,2GMRR@201174|Actinobacteria,234MG@1762|Mycobacteriaceae	201174|Actinobacteria	S	SEC-C motif	-	-	-	-	-	-	-	-	-	-	-	-	SEC-C
CMS1_k127_948193_3	575540.Isop_3052	3.104e-46	172.0	COG3476@1|root,COG3476@2|Bacteria,2J03F@203682|Planctomycetes	203682|Planctomycetes	T	PFAM TspO MBR family	-	-	-	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	-	-	-	ko00000,ko00001,ko02000	9.A.24	-	-	TspO_MBR
CMS1_k127_948193_9	457570.Nther_2563	1.414e-10	68.0	COG1708@1|root,COG1708@2|Bacteria,1VNM9@1239|Firmicutes,24S6I@186801|Clostridia	186801|Clostridia	L	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
CMS1_k127_948193_5	459495.SPLC1_S420180	1.726e-38	145.0	COG1669@1|root,COG1669@2|Bacteria,1G8GD@1117|Cyanobacteria,1HCDB@1150|Oscillatoriales	1117|Cyanobacteria	S	Nucleotidyltransferase domain	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
CMS1_k127_948193_6	13035.Dacsa_1953	4.446e-25	106.0	COG2886@1|root,COG2886@2|Bacteria	2|Bacteria	E	Uncharacterised protein family (UPF0175)	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox,UPF0175
CMS1_k127_948193_7	449447.MAE_45540	4.509e-15	76.0	COG2442@1|root,COG2442@2|Bacteria	2|Bacteria	K	InterPro IPR007367	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
CMS1_k127_949769_0	497964.CfE428DRAFT_3846	2.193e-155	501.0	COG4948@1|root,COG4948@2|Bacteria,46S7G@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Mandelate Racemase Muconate Lactonizing	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C
CMS1_k127_949769_2	649638.Trad_0115	1.221e-102	344.0	COG0111@1|root,COG0111@2|Bacteria,1WI3I@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EH	PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh_C
CMS1_k127_949769_3	351627.Csac_1292	6.402e-82	293.0	COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,42EQM@68295|Thermoanaerobacterales	186801|Clostridia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
CMS1_k127_949769_4	1502851.FG93_03293	6.938e-46	177.0	COG0329@1|root,COG0329@2|Bacteria,1MWV5@1224|Proteobacteria,2TRE1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EM	Belongs to the DapA family	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
CMS1_k127_949769_1	68170.KL590524_gene3561	3.434e-117	391.0	COG0395@1|root,COG1175@1|root,COG0395@2|Bacteria,COG1175@2|Bacteria,2GJ3P@201174|Actinobacteria,4EEPR@85010|Pseudonocardiales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025,ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_955324_1	316274.Haur_1430	5.892e-87	303.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2G699@200795|Chloroflexi,3764S@32061|Chloroflexia	200795|Chloroflexi	T	PFAM adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc
CMS1_k127_955324_4	926550.CLDAP_39030	1.526e-28	131.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2G699@200795|Chloroflexi	200795|Chloroflexi	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Guanylate_cyc,TPR_12
CMS1_k127_955324_3	357808.RoseRS_4136	2.938e-47	175.0	29YXA@1|root,30KTZ@2|Bacteria,2GB35@200795|Chloroflexi,377U3@32061|Chloroflexia	32061|Chloroflexia	S	Domain of unknown function (DUF4281)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4281
CMS1_k127_955324_2	1173029.JH980292_gene4263	2.491e-68	243.0	COG5464@1|root,COG5464@2|Bacteria,1G21N@1117|Cyanobacteria,1H8ZC@1150|Oscillatoriales	1117|Cyanobacteria	S	COGs COG5464 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF4351
CMS1_k127_955324_0	1173024.KI912148_gene2841	1.962e-133	436.0	COG1770@1|root,COG1770@2|Bacteria,1G1RH@1117|Cyanobacteria,1JHGU@1189|Stigonemataceae	1117|Cyanobacteria	E	Prolyl oligopeptidase, N-terminal beta-propeller domain	-	-	3.4.21.83	ko:K01354	ko05142,ko05143,map05142,map05143	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
CMS1_k127_963635_4	1449063.JMLS01000001_gene4202	9.695e-72	249.0	COG0673@1|root,COG0673@2|Bacteria,1TQ2Y@1239|Firmicutes,4H9YK@91061|Bacilli,26RMI@186822|Paenibacillaceae	91061|Bacilli	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_963635_5	706587.Desti_4300	5.221e-36	148.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
CMS1_k127_963635_3	1499967.BAYZ01000076_gene782	2.644e-92	314.0	COG0329@1|root,COG0329@2|Bacteria	2|Bacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	nanA	-	4.1.3.3,4.3.3.7	ko:K01639,ko:K01714	ko00261,ko00300,ko00520,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map00520,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R01811,R10147	RC00159,RC00600,RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
CMS1_k127_963635_1	926550.CLDAP_17270	2.414e-137	445.0	COG0673@1|root,COG0673@2|Bacteria,2G7X7@200795|Chloroflexi	200795|Chloroflexi	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
CMS1_k127_963635_6	526227.Mesil_2967	1.401e-27	125.0	COG0673@1|root,COG0673@2|Bacteria,1WKW4@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Oxidoreductase family, C-terminal alpha beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_963635_7	205918.Psyr_3007	1.503e-06	55.0	COG3326@1|root,COG3326@2|Bacteria,1N6YM@1224|Proteobacteria,1SCMX@1236|Gammaproteobacteria,1Z7Y6@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1294)	-	-	-	-	-	-	-	-	-	-	-	-	CSD,DUF1294
CMS1_k127_963635_2	1210908.HSB1_03340	3.792e-104	346.0	COG2421@1|root,arCOG01004@2157|Archaea,2XU60@28890|Euryarchaeota,23S6B@183963|Halobacteria	183963|Halobacteria	C	acetamidase formamidase	-	-	-	-	-	-	-	-	-	-	-	-	FmdA_AmdA
CMS1_k127_963635_0	1265503.KB905170_gene176	2.028e-315	1011.0	COG0642@1|root,COG2199@1|root,COG3292@1|root,COG2205@2|Bacteria,COG3292@2|Bacteria,COG3706@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,2Q7NV@267889|Colwelliaceae	1236|Gammaproteobacteria	T	Two component regulator propeller	-	-	-	ko:K19694	-	-	-	-	ko00000,ko01001,ko02022	-	-	-	7TMR-DISM_7TM,GGDEF,HAMP,HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y,dCache_1
CMS1_k127_964318_4	360095.BARBAKC583_1248	1.519e-06	57.0	COG1396@1|root,COG1396@2|Bacteria,1RDBW@1224|Proteobacteria,2U7CY@28211|Alphaproteobacteria,48U07@772|Bartonellaceae	28211|Alphaproteobacteria	K	Helix-turn-helix domain	MA20_23890	-	-	-	-	-	-	-	-	-	-	-	HTH_3
CMS1_k127_964318_1	311424.DhcVS_979	2.185e-212	683.0	COG0210@1|root,COG0210@2|Bacteria,2G5XF@200795|Chloroflexi,34D7Z@301297|Dehalococcoidia	301297|Dehalococcoidia	L	UvrD/REP helicase N-terminal domain	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
CMS1_k127_964318_3	886293.Sinac_6539	1.609e-07	59.0	2DCNA@1|root,2ZEQT@2|Bacteria,2J447@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_964318_2	671143.DAMO_1865	3.604e-210	670.0	COG0441@1|root,COG0441@2|Bacteria,2NNMT@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
CMS1_k127_964318_0	926550.CLDAP_20840	1.003e-267	829.0	COG0441@1|root,COG0441@2|Bacteria,2G5PZ@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
CMS1_k127_965853_4	478749.BRYFOR_09053	6.951e-30	124.0	COG1694@1|root,COG1694@2|Bacteria,1VA3E@1239|Firmicutes,24NYY@186801|Clostridia	186801|Clostridia	S	MazG nucleotide pyrophosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	MazG-like
CMS1_k127_965853_2	1232683.ADIMK_3753	5.229e-89	301.0	COG1028@1|root,COG1028@2|Bacteria,1MWJI@1224|Proteobacteria,1RY5G@1236|Gammaproteobacteria,46B36@72275|Alteromonadaceae	1236|Gammaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS1_k127_965853_5	326427.Cagg_0649	1.675e-16	94.0	COG0642@1|root,COG2205@2|Bacteria,2G5YI@200795|Chloroflexi,37540@32061|Chloroflexia	32061|Chloroflexia	T	N-terminal 7TM region of histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_7TM
CMS1_k127_965853_3	187303.BN69_2328	4.824e-31	130.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_965853_1	926550.CLDAP_41040	1.053e-91	334.0	COG5305@1|root,COG5305@2|Bacteria,2G7EE@200795|Chloroflexi	2|Bacteria	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS1_k127_965853_0	1128421.JAGA01000003_gene3691	2.423e-99	338.0	COG0420@1|root,COG0420@2|Bacteria,2NQ16@2323|unclassified Bacteria	2|Bacteria	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	-	ko:K03546,ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos
CMS1_k127_965853_6	316274.Haur_2160	4.062e-16	82.0	COG0695@1|root,COG0695@2|Bacteria	2|Bacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	-	-	1.20.4.3	ko:K18917	-	-	-	-	ko00000,ko01000	-	-	-	Glutaredoxin
CMS1_k127_965853_7	1424334.W822_15805	6.294e-12	72.0	COG1846@1|root,COG1846@2|Bacteria,1RF8X@1224|Proteobacteria,2VXCT@28216|Betaproteobacteria,3T3NK@506|Alcaligenaceae	28216|Betaproteobacteria	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	MarR
CMS1_k127_967080_2	870187.Thini_1378	1.574e-65	231.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1Q7PK@1224|Proteobacteria,1RSF0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_23,HTH_29,HTH_33
CMS1_k127_967080_3	329726.AM1_4197	1.577e-25	111.0	COG4584@1|root,COG4584@2|Bacteria,1GR4Q@1117|Cyanobacteria	2|Bacteria	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,Dimer_Tnp_Tn5,HTH_23
CMS1_k127_967080_0	926569.ANT_29930	2.913e-111	368.0	COG2116@1|root,COG2116@2|Bacteria,2G967@200795|Chloroflexi	200795|Chloroflexi	P	Formate/nitrite transporter	-	-	-	ko:K06212	-	-	-	-	ko00000,ko02000	1.A.16.1.1,1.A.16.1.3	-	-	Form_Nir_trans
CMS1_k127_967080_1	485913.Krac_7185	4.065e-78	279.0	COG3629@1|root,COG3629@2|Bacteria,2G88E@200795|Chloroflexi	2|Bacteria	K	SPTR Q471D1 TPR repeat Bacterial transcriptional activator domain Tetratricopeptide TPR_4	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,NACHT,NB-ARC,WD40
CMS1_k127_967080_4	1278078.G419_05125	2.579e-17	95.0	COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4FUTU@85025|Nocardiaceae	201174|Actinobacteria	K	activity, protein serine threonine kinase activity, protein-tyrosine kinase activity, ATP binding, regulation of transcription, DNA-dependent, protein amino acid phosphorylation	pknK_2	-	2.7.11.1	ko:K08282,ko:K13419	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_22,GerE,NB-ARC,Pkinase,TPR_12,TPR_7
CMS1_k127_973247_0	1501230.ET33_02970	9.651e-186	603.0	COG2909@1|root,COG2909@2|Bacteria,1UIMV@1239|Firmicutes,4HD7H@91061|Bacilli,26QDM@186822|Paenibacillaceae	91061|Bacilli	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
CMS1_k127_973247_1	1173027.Mic7113_4793	2.718e-101	354.0	COG1680@1|root,COG1680@2|Bacteria,1G4D0@1117|Cyanobacteria,1HFEP@1150|Oscillatoriales	1117|Cyanobacteria	V	PFAM beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
CMS1_k127_973247_2	1380347.JNII01000008_gene4406	5.763e-19	89.0	2DNVA@1|root,32ZBE@2|Bacteria,2GRAT@201174|Actinobacteria,4EWV7@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_973260_1	926560.KE387027_gene413	3.595e-63	226.0	COG2072@1|root,COG2072@2|Bacteria,1WM1X@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	Flavin-binding monooxygenase-like	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_3
CMS1_k127_973260_0	1128421.JAGA01000003_gene3678	1.252e-143	498.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2NQCZ@2323|unclassified Bacteria	2|Bacteria	K	NB-ARC domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,AAA_22,BTAD,NB-ARC,TPR_10,TPR_12,TPR_8,Trans_reg_C
CMS1_k127_973260_2	767817.Desgi_3970	1.824e-36	149.0	COG0740@1|root,COG0740@2|Bacteria,1UKGT@1239|Firmicutes,25FWY@186801|Clostridia	186801|Clostridia	OU	serine-type endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_973517_2	926550.CLDAP_25270	3.842e-105	348.0	COG1032@1|root,COG1032@2|Bacteria,2G6X0@200795|Chloroflexi	200795|Chloroflexi	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
CMS1_k127_973517_0	649638.Trad_1847	6.542e-134	439.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
CMS1_k127_973517_1	518766.Rmar_0188	1.253e-115	378.0	COG2897@1|root,COG2897@2|Bacteria,4NF85@976|Bacteroidetes	976|Bacteroidetes	P	sulfurtransferase	sseA	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
CMS1_k127_973517_4	272123.Anacy_4446	3.071e-21	97.0	COG2442@1|root,COG2442@2|Bacteria,1G7T6@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
CMS1_k127_973517_3	1499967.BAYZ01000141_gene6156	1.874e-34	136.0	COG4634@1|root,COG4634@2|Bacteria,2NRUB@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Mut7-C
CMS1_k127_978898_1	1120949.KB903357_gene4895	3.588e-09	59.0	COG0028@1|root,COG0028@2|Bacteria,2I9V6@201174|Actinobacteria	201174|Actinobacteria	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS1_k127_978898_0	1521187.JPIM01000004_gene3074	5.039e-22	112.0	COG0631@1|root,COG0631@2|Bacteria,2G72P@200795|Chloroflexi,374Z2@32061|Chloroflexia	32061|Chloroflexia	T	protein serine/threonine phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_981314_3	640510.BC1001_5118	5.384e-05	48.0	COG4961@1|root,COG4961@2|Bacteria,1N247@1224|Proteobacteria,2VVE5@28216|Betaproteobacteria,1K8V9@119060|Burkholderiaceae	28216|Betaproteobacteria	U	PFAM TadE family protein	tadG1	-	-	-	-	-	-	-	-	-	-	-	TadE
CMS1_k127_981314_0	926569.ANT_13370	4.44e-131	433.0	COG0464@1|root,COG0464@2|Bacteria,2G642@200795|Chloroflexi	200795|Chloroflexi	O	SMART AAA ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA
CMS1_k127_981314_2	639282.DEFDS_1216	7.383e-21	99.0	COG4715@1|root,COG4715@2|Bacteria,2GFDQ@200930|Deferribacteres	200930|Deferribacteres	S	Zinc finger, swim domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_981314_1	525904.Tter_2130	2.275e-50	192.0	COG2971@1|root,COG2971@2|Bacteria	2|Bacteria	G	N-acetylglucosamine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
CMS1_k127_982361_0	926569.ANT_09770	2.717e-162	525.0	COG0008@1|root,COG0008@2|Bacteria,2G5WU@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
CMS1_k127_982361_5	926550.CLDAP_08110	1.64e-84	292.0	COG0772@1|root,COG0772@2|Bacteria,2G6GW@200795|Chloroflexi	200795|Chloroflexi	D	Belongs to the SEDS family	-	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
CMS1_k127_982361_8	1069080.KB913028_gene706	5.052e-18	86.0	COG0851@1|root,COG0851@2|Bacteria,1VFST@1239|Firmicutes,4H5QX@909932|Negativicutes	909932|Negativicutes	D	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell	minE	-	-	ko:K03608	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinE
CMS1_k127_982361_4	1121335.Clst_0318	3.125e-110	362.0	COG2894@1|root,COG2894@2|Bacteria,1TP6P@1239|Firmicutes,249BB@186801|Clostridia,3WH0T@541000|Ruminococcaceae	186801|Clostridia	D	Belongs to the ParA family	minD	-	-	ko:K03609	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
CMS1_k127_982361_7	357808.RoseRS_1559	1.723e-39	155.0	COG0850@1|root,COG0850@2|Bacteria,2G6VN@200795|Chloroflexi,375JV@32061|Chloroflexia	32061|Chloroflexia	D	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization	minC	-	-	ko:K03610	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinC_C,MinC_N
CMS1_k127_982361_2	926550.CLDAP_08140	1.338e-147	496.0	COG0768@1|root,COG0768@2|Bacteria,2G64Z@200795|Chloroflexi	200795|Chloroflexi	M	PFAM penicillin-binding protein transpeptidase	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
CMS1_k127_982361_9	479434.Sthe_2014	0.0001189	51.0	COG2891@1|root,COG2891@2|Bacteria,2GBC9@200795|Chloroflexi,27YRC@189775|Thermomicrobia	189775|Thermomicrobia	M	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	MreD
CMS1_k127_982361_6	926550.CLDAP_08160	4.23e-47	181.0	COG1792@1|root,COG1792@2|Bacteria,2G743@200795|Chloroflexi	200795|Chloroflexi	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
CMS1_k127_982361_1	926550.CLDAP_08170	2.227e-149	480.0	COG1077@1|root,COG1077@2|Bacteria,2G62K@200795|Chloroflexi	200795|Chloroflexi	D	TIGRFAM cell shape determining protein, MreB Mrl family	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
CMS1_k127_982361_3	177437.HRM2_26180	3.951e-129	446.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,42NXT@68525|delta/epsilon subdivisions,2WIZ3@28221|Deltaproteobacteria,2MKIU@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc,Pkinase,TPR_12
CMS1_k127_985242_3	1144275.COCOR_03123	2.359e-48	191.0	COG1520@1|root,COG1520@2|Bacteria,1QV8R@1224|Proteobacteria,42N00@68525|delta/epsilon subdivisions,2WMF6@28221|Deltaproteobacteria,2YZAM@29|Myxococcales	28221|Deltaproteobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_985242_5	1463917.JODC01000007_gene7491	2.687e-35	137.0	COG3070@1|root,COG3070@2|Bacteria,2IKKV@201174|Actinobacteria	201174|Actinobacteria	K	TfoX N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
CMS1_k127_985242_4	105559.Nwat_0046	4.061e-39	149.0	COG0399@1|root,COG0399@2|Bacteria,1N0QW@1224|Proteobacteria,1S8YK@1236|Gammaproteobacteria,1X28T@135613|Chromatiales	135613|Chromatiales	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
CMS1_k127_985242_0	926550.CLDAP_22570	3.598e-130	425.0	COG1158@1|root,COG1158@2|Bacteria,2G5UQ@200795|Chloroflexi	200795|Chloroflexi	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	-	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_RNA_bind
CMS1_k127_985242_1	316067.Geob_2072	4.784e-78	274.0	COG1148@1|root,COG1148@2|Bacteria,1RB0H@1224|Proteobacteria,42QQV@68525|delta/epsilon subdivisions,2WN7E@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
CMS1_k127_985242_6	1499967.BAYZ01000069_gene1864	8.725e-30	121.0	COG2886@1|root,COG2886@2|Bacteria	2|Bacteria	E	Uncharacterised protein family (UPF0175)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0175
CMS1_k127_985242_2	1121904.ARBP01000019_gene2730	1.833e-50	184.0	COG0667@1|root,COG0667@2|Bacteria,4NP8D@976|Bacteroidetes	976|Bacteroidetes	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS1_k127_98857_2	926550.CLDAP_10200	2.149e-148	473.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
CMS1_k127_98857_3	926550.CLDAP_10190	1.267e-138	446.0	COG1175@1|root,COG1175@2|Bacteria,2G80Q@200795|Chloroflexi	200795|Chloroflexi	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_98857_0	926550.CLDAP_10180	6.902e-159	507.0	COG0395@1|root,COG0395@2|Bacteria	2|Bacteria	P	glycerophosphodiester transmembrane transport	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
CMS1_k127_98857_4	251221.35211045	3.637e-69	243.0	COG2746@1|root,COG2746@2|Bacteria,1G8Z6@1117|Cyanobacteria	1117|Cyanobacteria	V	Aminoglycoside 3-N-acetyltransferase	-	-	2.3.1.81	ko:K00662	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Antibiotic_NAT
CMS1_k127_98857_1	1183438.GKIL_1936	1.138e-154	527.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,1G5W7@1117|Cyanobacteria	1117|Cyanobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,TPR_12
CMS1_k127_98857_6	394221.Mmar10_1682	0.0001959	47.0	COG2730@1|root,COG2730@2|Bacteria,1PUWU@1224|Proteobacteria,2V6EP@28211|Alphaproteobacteria,43ZQQ@69657|Hyphomonadaceae	28211|Alphaproteobacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_98857_5	383372.Rcas_1386	9.649e-16	81.0	COG0371@1|root,COG0371@2|Bacteria,2G95F@200795|Chloroflexi	200795|Chloroflexi	C	Iron-containing alcohol dehydrogenase	-	-	1.1.1.261	ko:K00096	ko00564,map00564	-	R05679,R05680	RC00029	ko00000,ko00001,ko01000	-	-	-	Fe-ADH_2
CMS1_k127_992668_1	479434.Sthe_2433	1.848e-85	287.0	COG0277@1|root,COG0277@2|Bacteria,2G7TD@200795|Chloroflexi	200795|Chloroflexi	C	D-arabinono-1,4-lactone oxidase	-	-	-	-	-	-	-	-	-	-	-	-	ALO,FAD_binding_4
CMS1_k127_992668_6	585.DR95_2354	0.0003459	53.0	28N4R@1|root,2ZBA5@2|Bacteria,1QUE6@1224|Proteobacteria,1RSJN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_992668_3	1234664.AMRO01000025_gene2060	1.21e-57	210.0	COG1028@1|root,COG1028@2|Bacteria,1TR5M@1239|Firmicutes,4HCD2@91061|Bacilli,1WF10@129337|Geobacillus	91061|Bacilli	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
CMS1_k127_992668_0	1274374.CBLK010000056_gene256	6.127e-91	310.0	COG4209@1|root,COG4209@2|Bacteria,1TP33@1239|Firmicutes,4HD71@91061|Bacilli,26QGE@186822|Paenibacillaceae	91061|Bacilli	G	binding-protein-dependent transport systems inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
CMS1_k127_992668_5	1274374.CBLK010000056_gene254	2.656e-31	140.0	COG1653@1|root,COG1653@2|Bacteria,1V5AZ@1239|Firmicutes,4HHD2@91061|Bacilli,276P0@186822|Paenibacillaceae	91061|Bacilli	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_1,SBP_bac_8
CMS1_k127_992668_2	1536769.P40081_30400	1.708e-67	239.0	COG0395@1|root,COG0395@2|Bacteria,1VR6P@1239|Firmicutes,4HUME@91061|Bacilli,26QUY@186822|Paenibacillaceae	91061|Bacilli	G	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K17320	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
CMS1_k127_992668_4	1033806.HTIA_0726	2.576e-53	194.0	COG1312@1|root,arCOG05324@2157|Archaea,2XU9K@28890|Euryarchaeota,23UJN@183963|Halobacteria	183963|Halobacteria	G	COG1312 D-mannonate dehydratase	-	-	4.2.1.8	ko:K01686	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	UxuA
CMS1_k127_994626_3	32049.SYNPCC7002_A2286	1.682e-65	226.0	COG0581@1|root,COG0581@2|Bacteria,1G2GA@1117|Cyanobacteria,1H3WW@1129|Synechococcus	1117|Cyanobacteria	P	Phosphate transport system permease	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
CMS1_k127_994626_0	926550.CLDAP_00810	4.062e-123	401.0	COG1117@1|root,COG1117@2|Bacteria,2G646@200795|Chloroflexi	200795|Chloroflexi	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
CMS1_k127_994626_2	552811.Dehly_1323	2.029e-72	258.0	COG0704@1|root,COG0704@2|Bacteria,2G6HD@200795|Chloroflexi,34D3P@301297|Dehalococcoidia	301297|Dehalococcoidia	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
CMS1_k127_994626_1	926569.ANT_11940	2.592e-99	330.0	COG1521@1|root,COG1521@2|Bacteria,2G6B4@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
CMS1_k127_994626_4	1408254.T458_17280	9.655e-51	185.0	COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,4HAK8@91061|Bacilli,26R8P@186822|Paenibacillaceae	91061|Bacilli	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
CMS1_k127_995804_0	926550.CLDAP_09480	4.601e-189	606.0	COG0465@1|root,COG0465@2|Bacteria,2G5J3@200795|Chloroflexi	200795|Chloroflexi	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
CMS1_k127_995804_2	935836.JAEL01000010_gene3715	3.444e-116	383.0	COG0460@1|root,COG0460@2|Bacteria,1URXW@1239|Firmicutes,4HBHY@91061|Bacilli,1ZC5K@1386|Bacillus	91061|Bacilli	E	Homoserine dehydrogenase	-	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	Homoserine_dh,NAD_binding_3
CMS1_k127_995804_4	316274.Haur_2220	1.497e-40	164.0	2A4MU@1|root,30T8S@2|Bacteria,2GB68@200795|Chloroflexi,377F3@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_995804_5	1123288.SOV_1c06440	3.49e-23	110.0	COG2227@1|root,COG2227@2|Bacteria,1UXZZ@1239|Firmicutes	1239|Firmicutes	H	Methyltransferase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
CMS1_k127_995804_1	313612.L8106_10392	2.028e-147	499.0	COG0745@1|root,COG2208@1|root,COG3452@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2208@2|Bacteria,COG3452@2|Bacteria,COG5002@2|Bacteria,1G160@1117|Cyanobacteria,1H75U@1150|Oscillatoriales	1117|Cyanobacteria	KT	Stage II sporulation protein E	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	CHASE,HATPase_c,HisKA,Response_reg,SpoIIE
CMS1_k127_995804_3	926550.CLDAP_31350	1.521e-81	291.0	COG5305@1|root,COG5305@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS1_k127_997427_4	1128421.JAGA01000003_gene3257	9.512e-36	139.0	COG2208@1|root,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,SpoIIE
CMS1_k127_997427_3	756067.MicvaDRAFT_4725	1.569e-52	193.0	COG4191@1|root,COG4191@2|Bacteria,1G2US@1117|Cyanobacteria,1H8YF@1150|Oscillatoriales	1117|Cyanobacteria	T	SMART Signal transduction response regulator, receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
CMS1_k127_997427_2	1501230.ET33_29415	5.323e-59	213.0	COG1028@1|root,COG1028@2|Bacteria,1TSPJ@1239|Firmicutes,4HCGT@91061|Bacilli,26VZM@186822|Paenibacillaceae	91061|Bacilli	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS1_k127_997427_0	525904.Tter_1959	9.774e-213	668.0	COG1486@1|root,COG1486@2|Bacteria	2|Bacteria	G	melibiose metabolic process	-	-	3.2.1.22,3.2.1.86	ko:K01222,ko:K07406	ko00010,ko00052,ko00500,ko00561,ko00600,ko00603,map00010,map00052,map00500,map00561,map00600,map00603	-	R00839,R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05133,R05134,R05549,R05961,R06091	RC00049,RC00059,RC00171,RC00451,RC00714	ko00000,ko00001,ko01000	-	GT4	iLJ478.TM1068	Glyco_hydro_4,Glyco_hydro_4C
CMS1_k127_997427_7	502025.Hoch_5415	5.805e-30	122.0	COG2154@1|root,COG2154@2|Bacteria,1RIEN@1224|Proteobacteria,43765@68525|delta/epsilon subdivisions,2X24N@28221|Deltaproteobacteria,2YW4N@29|Myxococcales	28221|Deltaproteobacteria	H	pterin-4-alpha-carbinolamine dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
CMS1_k127_997427_5	926550.CLDAP_08190	1.009e-35	141.0	COG2606@1|root,COG2606@2|Bacteria,2G9C3@200795|Chloroflexi	200795|Chloroflexi	S	Aminoacyl-tRNA editing domain	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
CMS1_k127_997427_8	316274.Haur_1271	2.267e-08	61.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HATPase_c,Response_reg
CMS1_k127_997427_1	215803.DB30_4979	1.062e-172	557.0	COG0028@1|root,COG0028@2|Bacteria,1MXDW@1224|Proteobacteria,42NVI@68525|delta/epsilon subdivisions,2WJTD@28221|Deltaproteobacteria,2YTYS@29|Myxococcales	28221|Deltaproteobacteria	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS1_k127_997427_6	926569.ANT_28060	8.451e-35	134.0	COG0336@1|root,COG0336@2|Bacteria,2G5MY@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
## 6329 queries scanned
## Total time (seconds): 93.79138016700745
## Rate: 67.48 q/s