## Mon Feb 16 05:31:32 2026 ## emapper-2.1.13 ## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/bins/CMS1_bin.18.fa -m mmseqs --output CMS1_bin.18 --output_dir /data/result/bins/wyx/eggqs50+/CMS1_bin.18 --itype genome --cpu 8 --override ## #query seed_ortholog evalue score eggNOG_OGs max_annot_lvl COG_category Description Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction PFAMs CMS1_k127_1005489_2 1304877.KI519399_gene2432 3.347e-119 391.0 COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,2TVFA@28211|Alphaproteobacteria,3JSH4@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Transporter associated domain tlyC - - ko:K06189 - - - - ko00000,ko02000 9.A.40.1.2 - - CBS,CorC_HlyC CMS1_k127_1005489_0 316057.RPD_0238 4.54e-223 706.0 COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,2TQRC@28211|Alphaproteobacteria,3JQPB@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Transfers the fatty acyl group on membrane lipoproteins lnt - - ko:K03820 - - - - ko00000,ko01000 - GT2 - CN_hydrolase CMS1_k127_1005489_7 78245.Xaut_1815 2.447e-56 199.0 COG1396@1|root,COG1396@2|Bacteria,1RDBW@1224|Proteobacteria,2U7CY@28211|Alphaproteobacteria,3EZDW@335928|Xanthobacteraceae 28211|Alphaproteobacteria K Helix-turn-helix XRE-family like proteins MA20_23890 - - - - - - - - - - - HTH_3 CMS1_k127_1005489_1 402881.Plav_3623 1.78e-159 514.0 COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,2TR4P@28211|Alphaproteobacteria,1JMYV@119043|Rhodobiaceae 28211|Alphaproteobacteria H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme metK - 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 - - - S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N CMS1_k127_1005489_5 1187851.A33M_4126 1.066e-81 279.0 COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,2TUU9@28211|Alphaproteobacteria,3FD47@34008|Rhodovulum 28211|Alphaproteobacteria J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA trmB GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 ko:K03439 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_4 CMS1_k127_1005489_4 1230476.C207_02318 1.801e-84 293.0 COG5330@1|root,COG5330@2|Bacteria,1R3VY@1224|Proteobacteria,2TSZ2@28211|Alphaproteobacteria,3JV4H@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Uncharacterised protein conserved in bacteria (DUF2336) - - - - - - - - - - - - DUF2336 CMS1_k127_1005489_6 316057.RPD_0234 1.143e-75 259.0 COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,2TS4E@28211|Alphaproteobacteria,3JTND@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Required for maturation of 30S ribosomal subunits rimP GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - ko:K09748 - - - - ko00000,ko03009 - - - DUF150,DUF150_C CMS1_k127_1005489_3 1187851.A33M_0732 5.912e-109 354.0 COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,2TRQN@28211|Alphaproteobacteria,3FCQ9@34008|Rhodovulum 28211|Alphaproteobacteria J Participates in both transcription termination and antitermination nusA - - ko:K02600 - - - - ko00000,ko03009,ko03021 - - - HHH_5,KH_5,NusA_N,S1 CMS1_k127_1008358_3 443598.AUFA01000005_gene3613 8.913e-108 355.0 COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,2TRBP@28211|Alphaproteobacteria,3JTTT@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) ppk - 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PP_kinase,PP_kinase_C,PP_kinase_N CMS1_k127_1008358_4 709797.CSIRO_2647 9.122e-84 291.0 COG0593@1|root,COG0593@2|Bacteria,1N4PG@1224|Proteobacteria,2U96K@28211|Alphaproteobacteria,3JQY4@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L Bacterial dnaA protein hda - - - - - - - - - - - Bac_DnaA CMS1_k127_1008358_2 1120792.JAFV01000001_gene960 2.413e-130 435.0 COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,2TRD3@28211|Alphaproteobacteria,36XIX@31993|Methylocystaceae 28211|Alphaproteobacteria S AI-2E family transporter perM - - ko:K03548 - - - - ko00000,ko02000 2.A.86.1 - - AI-2E_transport CMS1_k127_1008358_6 316057.RPD_2954 1.342e-72 255.0 COG0558@1|root,COG0558@2|Bacteria,1MZ8B@1224|Proteobacteria,2U7AP@28211|Alphaproteobacteria,3JT6T@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I CDP-alcohol phosphatidyltransferase MA20_28295 - 2.7.8.41,2.7.8.5 ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 - R01801,R02030 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf CMS1_k127_1008358_1 323097.Nham_2118 2.335e-168 535.0 COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,2TR6G@28211|Alphaproteobacteria,3JRRD@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria F Phosphoribosylformylglycinamidine cyclo-ligase purM - 6.3.3.1 ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04208 RC01100 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C CMS1_k127_1008358_5 1380355.JNIJ01000017_gene4711 1.381e-83 282.0 COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,2TRY6@28211|Alphaproteobacteria,3JS16@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate purN GO:0003674,GO:0003824,GO:0004644,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716 2.1.2.2 ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - - Formyl_trans_N,YjbR CMS1_k127_1008358_7 1380394.JADL01000001_gene2991 1.208e-31 129.0 COG2259@1|root,COG2259@2|Bacteria,1RDYW@1224|Proteobacteria,2UCQJ@28211|Alphaproteobacteria,2JTCM@204441|Rhodospirillales 204441|Rhodospirillales S DoxX - - - ko:K15977 - - - - ko00000 - - - DoxX CMS1_k127_1008358_0 883078.HMPREF9695_04340 0.0 1128.0 COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,2TTAY@28211|Alphaproteobacteria,3JSTW@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family MA20_38000 - - - - - - - - - - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding CMS1_k127_1008358_8 1187851.A33M_2401 0.0001454 46.0 COG0861@1|root,COG0861@2|Bacteria,1QZU6@1224|Proteobacteria,2TURK@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Integral membrane protein TerC MA20_28265 - - - - - - - - - - - TerC CMS1_k127_1012435_3 675635.Psed_1033 2.221e-27 116.0 COG0154@1|root,COG0154@2|Bacteria,2GKPZ@201174|Actinobacteria,4E1PC@85010|Pseudonocardiales 201174|Actinobacteria J Belongs to the amidase family - - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase CMS1_k127_1012435_4 316055.RPE_1673 4.003e-06 50.0 COG1801@1|root,COG1801@2|Bacteria,1MU7F@1224|Proteobacteria,2TT1D@28211|Alphaproteobacteria,3JRQY@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function DUF72 MA20_09500 - - - - - - - - - - - DUF72 CMS1_k127_1012435_0 1040989.AWZU01000004_gene6990 6.329e-303 936.0 COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,2TS07@28211|Alphaproteobacteria,3JTI3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL - - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 CMS1_k127_1012435_1 420324.KI911948_gene9173 1.554e-51 185.0 COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,2U9AQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter groS GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 CMS1_k127_1012435_2 883078.HMPREF9695_02576 1.404e-41 154.0 COG5425@1|root,COG5425@2|Bacteria,1N08I@1224|Proteobacteria,2UBVR@28211|Alphaproteobacteria,3JZGZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Usg-like family MA20_32470 - - - - - - - - - - - Usg CMS1_k127_1029040_0 709797.CSIRO_1773 2.073e-256 802.0 COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,2TQKJ@28211|Alphaproteobacteria,3JRW9@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Glycyl-tRNA synthetase beta subunit glyS - 6.1.1.14 ko:K01879 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_1,tRNA_synt_2f CMS1_k127_103357_8 292415.Tbd_1049 8.768e-24 104.0 COG3865@1|root,COG3865@2|Bacteria,1N7IY@1224|Proteobacteria,2VSAQ@28216|Betaproteobacteria,1KTCK@119069|Hydrogenophilales 119069|Hydrogenophilales S 3-demethylubiquinone-9 3-methyltransferase - - - - - - - - - - - - 3-dmu-9_3-mt CMS1_k127_103357_3 292415.Tbd_2635 2.058e-64 224.0 COG0494@1|root,COG0494@2|Bacteria,1MYSK@1224|Proteobacteria,2W3WC@28216|Betaproteobacteria 28216|Betaproteobacteria L NUDIX domain - - - - - - - - - - - - NUDIX CMS1_k127_103357_2 1049564.TevJSym_bh00190 3.543e-77 271.0 COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1RYRB@1236|Gammaproteobacteria,1JA3N@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B CMS1_k127_103357_6 1487953.JMKF01000054_gene1573 6.324e-42 160.0 COG2128@1|root,COG2128@2|Bacteria,1GDIA@1117|Cyanobacteria 1117|Cyanobacteria S Carboxymuconolactone decarboxylase family - - - - - - - - - - - - CMD CMS1_k127_103357_0 768671.ThimaDRAFT_0841 2.764e-122 413.0 COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1S720@1236|Gammaproteobacteria,1WYW3@135613|Chromatiales 135613|Chromatiales O Tetratricopeptide repeats - - - - - - - - - - - - TPR_16,TPR_8,Trans_reg_C CMS1_k127_103357_4 1123392.AQWL01000003_gene467 5.67e-59 208.0 COG4831@1|root,COG4831@2|Bacteria,1NMBS@1224|Proteobacteria 2|Bacteria S Uncharacterized conserved protein (DUF2173) - - - - - - - - - - - - DUF2173 CMS1_k127_103357_5 1123392.AQWL01000003_gene466 3.434e-51 183.0 COG4831@1|root,COG4831@2|Bacteria,1N4ET@1224|Proteobacteria 1224|Proteobacteria S Uncharacterized conserved protein (DUF2173) - - - - - - - - - - - - DUF2173 CMS1_k127_103357_7 292415.Tbd_1461 2.11e-34 139.0 COG4831@1|root,COG4831@2|Bacteria 2|Bacteria S Uncharacterized conserved protein (DUF2173) - - - - - - - - - - - - DUF2173 CMS1_k127_103357_1 1123368.AUIS01000032_gene1394 7e-105 353.0 COG1080@1|root,COG1080@2|Bacteria 2|Bacteria G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) ptsI - 2.7.3.9 ko:K08483 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 8.A.7 - - PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C CMS1_k127_1035227_2 1144319.PMI16_04569 0.0004509 46.0 COG0683@1|root,COG0683@2|Bacteria,1MV3Y@1224|Proteobacteria,2VJRG@28216|Betaproteobacteria 28216|Betaproteobacteria E Extracellular liganD-binding receptor - - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 CMS1_k127_1035227_0 1122603.ATVI01000006_gene324 2.725e-102 344.0 COG2141@1|root,COG2141@2|Bacteria,1NX0H@1224|Proteobacteria,1SZ37@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Luciferase-like monooxygenase luxB - 1.14.14.3 ko:K15854 ko02020,ko02024,map02020,map02024 - R10551 RC00080 ko00000,ko00001,ko01000 - - - Bac_luciferase CMS1_k127_1035227_1 331869.BAL199_17953 5.352e-40 151.0 COG0477@1|root,COG2814@2|Bacteria,1MX2P@1224|Proteobacteria,2TWIP@28211|Alphaproteobacteria,4BRIJ@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 CMS1_k127_1044978_0 1452718.JBOY01000035_gene2069 3.03e-311 959.0 COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,1RMWS@1236|Gammaproteobacteria 1236|Gammaproteobacteria F bifunctional purine biosynthesis protein purh purH GO:0003674,GO:0003824,GO:0004643,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 - - iEcHS_1320.EcHS_A4240,iPC815.YPO3728 AICARFT_IMPCHas,MGS CMS1_k127_1044978_2 1294143.H681_21720 9.232e-53 188.0 COG2901@1|root,COG2901@2|Bacteria,1N7MJ@1224|Proteobacteria,1SD35@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters fis GO:0000018,GO:0000229,GO:0000785,GO:0000786,GO:0000787,GO:0000789,GO:0000976,GO:0000984,GO:0000985,GO:0001017,GO:0001046,GO:0001047,GO:0001067,GO:0001121,GO:0001130,GO:0001131,GO:0001140,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008301,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016032,GO:0016070,GO:0018130,GO:0019042,GO:0019045,GO:0019046,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031421,GO:0032359,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0042803,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044374,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044427,GO:0044444,GO:0044446,GO:0044464,GO:0044815,GO:0045892,GO:0045893,GO:0045911,GO:0045934,GO:0045935,GO:0046483,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051054,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - ko:K03557 ko05111,map05111 - - - ko00000,ko00001,ko03000,ko03036,ko03400 - - - HTH_8 CMS1_k127_1044978_1 1182590.BN5_03413 1.397e-177 560.0 COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,1RMJP@1236|Gammaproteobacteria,1YF9V@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines dusB GO:0002943,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009314,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016627,GO:0017150,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050896,GO:0055114,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 - ko:K05540 - - - - ko00000,ko01000,ko03016 - - - Dus CMS1_k127_1044978_3 1395571.TMS3_0106195 3.266e-28 113.0 COG1273@1|root,COG1273@2|Bacteria,1MWCU@1224|Proteobacteria,1RYQ0@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Mj0042 family finger-like - - - - - - - - - - - - DUF3426,zinc_ribbon_4,zinc_ribbon_5 CMS1_k127_1045085_0 224911.27352567 1.783e-236 755.0 COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,2TRX2@28211|Alphaproteobacteria,3JSGG@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs rne - 3.1.26.12 ko:K08300 ko03018,map03018 M00394 - - ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 - - - RNase_E_G,S1 CMS1_k127_1053251_4 1218076.BAYB01000002_gene572 5.062e-13 70.0 COG1846@1|root,COG1846@2|Bacteria,1N7G0@1224|Proteobacteria,2VU14@28216|Betaproteobacteria,1K787@119060|Burkholderiaceae 28216|Betaproteobacteria K transcriptional regulator PadR family protein - - - - - - - - - - - - MarR,MarR_2 CMS1_k127_1053251_0 883078.HMPREF9695_04807 3.529e-184 586.0 COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,2TRN1@28211|Alphaproteobacteria,3JSH2@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine coaBC - 4.1.1.36,6.3.2.5 ko:K13038,ko:K21977 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 - - - DFP,Flavoprotein CMS1_k127_1053251_2 1125973.JNLC01000010_gene1228 2.384e-54 206.0 COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,2U7B5@28211|Alphaproteobacteria,3JYQC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA dut GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00053 R02100,R11896 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 - - - dUTPase CMS1_k127_1053251_3 1123229.AUBC01000008_gene444 4.454e-39 151.0 COG1959@1|root,COG1959@2|Bacteria,1RIJ8@1224|Proteobacteria,2U744@28211|Alphaproteobacteria,3K1QD@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K Transcriptional regulator - - - - - - - - - - - - Rrf2 CMS1_k127_1053251_1 504832.OCAR_4487 1.251e-114 387.0 COG0642@1|root,COG2205@2|Bacteria,1MVY8@1224|Proteobacteria,2TS5B@28211|Alphaproteobacteria,3JTRQ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Histidine kinase divL GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - HATPase_c,HisKA,PAS_7,PAS_8 CMS1_k127_1063764_1 438753.AZC_2855 1.575e-129 416.0 COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,2TRPR@28211|Alphaproteobacteria,3EYX6@335928|Xanthobacteraceae 28211|Alphaproteobacteria L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071496 - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA CMS1_k127_1063764_0 323098.Nwi_0189 1.821e-133 433.0 COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,2TS3N@28211|Alphaproteobacteria,3JTMB@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O Belongs to the peptidase M48B family htpX - - ko:K03799 - M00743 - - ko00000,ko00002,ko01000,ko01002 - - - Peptidase_M48 CMS1_k127_1063764_2 438753.AZC_2854 1.753e-104 343.0 COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,2TQV4@28211|Alphaproteobacteria,3EYTE@335928|Xanthobacteraceae 28211|Alphaproteobacteria J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD CMS1_k127_106470_11 713586.KB900536_gene2522 5.221e-29 115.0 COG1053@1|root,COG1053@2|Bacteria,1NZBR@1224|Proteobacteria,1RZ0U@1236|Gammaproteobacteria,1WW7B@135613|Chromatiales 135613|Chromatiales C reductase, alpha subunit - - 1.8.99.2 ko:K00394 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00596 R00860,R04927,R08553 RC00007,RC01239,RC02862 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C CMS1_k127_106470_7 580332.Slit_1716 1.04e-45 170.0 2BK43@1|root,32EHP@2|Bacteria,1RDAC@1224|Proteobacteria,2W3NZ@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_106470_4 1158182.KB905021_gene535 3.788e-69 239.0 COG1047@1|root,COG1047@2|Bacteria,1REQ1@1224|Proteobacteria,1S2MS@1236|Gammaproteobacteria,1WY6J@135613|Chromatiales 135613|Chromatiales O Peptidyl-prolyl cis-trans - - 5.2.1.8 ko:K03775 - - - - ko00000,ko01000,ko03110 - - - - CMS1_k127_106470_12 1266908.AQPB01000061_gene1235 5.255e-20 89.0 2E4KB@1|root,32ZFA@2|Bacteria,1N6R9@1224|Proteobacteria,1SFP8@1236|Gammaproteobacteria,1WZH8@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - CMS1_k127_106470_1 340177.Cag_1587 1.193e-158 509.0 COG2046@1|root,COG2046@2|Bacteria,1FF05@1090|Chlorobi 1090|Chlorobi F sulfate assimilation sat - 2.7.7.4 ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00529,R04929 RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - ATP-sulfurylase,PUA_2 CMS1_k127_106470_10 1207063.P24_01395 1.408e-39 157.0 COG1409@1|root,COG1409@2|Bacteria,1MWKX@1224|Proteobacteria,2U5HA@28211|Alphaproteobacteria,2JRUX@204441|Rhodospirillales 204441|Rhodospirillales S Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes cpdA - 3.1.4.53 ko:K03651 ko00230,ko02025,map00230,map02025 - R00191 RC00296 ko00000,ko00001,ko01000 - - - Metallophos CMS1_k127_106470_2 1192868.CAIU01000015_gene1966 1.032e-141 459.0 COG2391@1|root,COG2391@2|Bacteria,1MXSE@1224|Proteobacteria,2TRUQ@28211|Alphaproteobacteria,43HTU@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Sulphur transport - - - ko:K07112 - - - - ko00000 - - - Sulf_transp CMS1_k127_106470_9 391937.NA2_18305 3.428e-43 161.0 COG0640@1|root,COG0640@2|Bacteria,1N72Q@1224|Proteobacteria,2UFSY@28211|Alphaproteobacteria,43KJU@69277|Phyllobacteriaceae 28211|Alphaproteobacteria K transcriptional regulator soxR GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - - - - - - - - - - HTH_5 CMS1_k127_106470_6 1177928.TH2_13814 9.75e-52 188.0 COG2010@1|root,COG2010@2|Bacteria,1RIV2@1224|Proteobacteria,2U9C5@28211|Alphaproteobacteria,2JT7V@204441|Rhodospirillales 204441|Rhodospirillales C cytochrome c - - - ko:K17223 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 - - - Cytochrom_C CMS1_k127_106470_5 1120956.JHZK01000001_gene3490 6.093e-57 205.0 COG5501@1|root,COG5501@2|Bacteria,1RH4J@1224|Proteobacteria,2U72E@28211|Alphaproteobacteria,1JQ2U@119043|Rhodobiaceae 28211|Alphaproteobacteria S Sulfur oxidation protein SoxY soxY - - ko:K17226 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 - - - SoxY CMS1_k127_106470_8 411684.HPDFL43_11126 2.191e-45 167.0 COG5501@1|root,COG5501@2|Bacteria,1N097@1224|Proteobacteria,2U94T@28211|Alphaproteobacteria,43KEW@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Sulphur oxidation protein SoxZ soxZ - - ko:K17227 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 - - - SoxZ CMS1_k127_106470_3 1192868.CAIU01000015_gene1958 1.536e-134 434.0 COG3258@1|root,COG3258@2|Bacteria,1MXB0@1224|Proteobacteria,2TTDW@28211|Alphaproteobacteria,43IAF@69277|Phyllobacteriaceae 28211|Alphaproteobacteria C C-type diheme cytochrome, which is part of the SoxAX cytochrome complex involved in sulfur oxidation. The SoxAX complex catalyzes the formation of a heterodisulfide bond between the conserved cysteine residue on a sulfur carrier SoxYZ complex subunit SoxY and thiosulfate or other inorganic sulfur substrates. This leads to the liberation of two electrons, which may be transferred from the SoxAX complex to another cytochrome c that then channels them into the respiratory electron transport chain. Some electrons may be used for reductive CO(2) fixation soxA GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005623,GO:0006091,GO:0006464,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009055,GO:0009987,GO:0016491,GO:0016667,GO:0016669,GO:0016740,GO:0016782,GO:0016783,GO:0018192,GO:0018193,GO:0018198,GO:0018307,GO:0019417,GO:0019418,GO:0019538,GO:0020037,GO:0022900,GO:0032991,GO:0036211,GO:0042597,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046872,GO:0046906,GO:0046914,GO:0046982,GO:0046983,GO:0048037,GO:0055114,GO:0070069,GO:0071704,GO:0097159,GO:0098822,GO:1901363,GO:1901564 - ko:K17222 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 - - - - CMS1_k127_106470_0 1120956.JHZK01000001_gene3493 2.597e-244 762.0 COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,2TUAE@28211|Alphaproteobacteria,1JPYX@119043|Rhodobiaceae 28211|Alphaproteobacteria F 5'-nucleotidase, C-terminal domain soxB - - ko:K17224 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 - - - 5_nucleotid_C,Metallophos CMS1_k127_1077154_4 460265.Mnod_2431 8.729e-37 154.0 COG0457@1|root,COG4249@1|root,COG0457@2|Bacteria,COG4249@2|Bacteria,1RKBA@1224|Proteobacteria,2TRAV@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Tetratricopeptide TPR_2 repeat protein - - - - - - - - - - - - Peptidase_C14,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8 CMS1_k127_1077154_3 595536.ADVE02000001_gene810 5.309e-89 300.0 COG0293@1|root,COG0293@2|Bacteria,1MW1C@1224|Proteobacteria,2TSBW@28211|Alphaproteobacteria,36XU7@31993|Methylocystaceae 28211|Alphaproteobacteria J FtsJ-like methyltransferase ftsJ - 2.1.1.166 ko:K02427 - - - - ko00000,ko01000,ko03009 - - - FtsJ CMS1_k127_1077154_1 1125973.JNLC01000002_gene2021 3.686e-128 419.0 COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,2TT2C@28211|Alphaproteobacteria,3JRA2@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria FP Ppx/GppA phosphatase family ppx - 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 - R03409 RC00002 ko00000,ko00001,ko01000 - - - Ppx-GppA CMS1_k127_1077154_0 1040989.AWZU01000020_gene1990 2.124e-311 973.0 COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TQMW@28211|Alphaproteobacteria,3JQVN@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain MA20_27485 - 1.2.5.3 ko:K03520 - - R11168 RC02800 ko00000,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 CMS1_k127_1077154_2 1380394.JADL01000001_gene2973 4.169e-111 372.0 COG2271@1|root,COG2271@2|Bacteria,1QU9E@1224|Proteobacteria,2TWHH@28211|Alphaproteobacteria,2JR0J@204441|Rhodospirillales 204441|Rhodospirillales G Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 CMS1_k127_1082890_14 670292.JH26_07760 3.239e-34 134.0 COG2321@1|root,COG2321@2|Bacteria,1MU4U@1224|Proteobacteria,2TRCS@28211|Alphaproteobacteria,1JRZY@119045|Methylobacteriaceae 28211|Alphaproteobacteria S Putative neutral zinc metallopeptidase - - - ko:K07054 - - - - ko00000 - - - Zn_peptidase CMS1_k127_1082890_2 1040989.AWZU01000009_gene1112 1.112e-191 603.0 COG2189@1|root,COG2189@2|Bacteria,1MX9M@1224|Proteobacteria,2TSW9@28211|Alphaproteobacteria,3JT5A@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L Belongs to the N(4) N(6)-methyltransferase family ccrM - 2.1.1.72 ko:K13581 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko02048 - - - N6_N4_Mtase CMS1_k127_1082890_8 1038859.AXAU01000020_gene5398 7.302e-71 245.0 COG2755@1|root,COG2755@2|Bacteria,1MWT8@1224|Proteobacteria,2TTXF@28211|Alphaproteobacteria,3JRB1@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Domain of Unknown Function (DUF1080) - - - - - - - - - - - - DUF1080 CMS1_k127_1082890_10 1037409.BJ6T_85990 6.678e-55 198.0 COG1546@1|root,COG1546@2|Bacteria,1RHXH@1224|Proteobacteria,2UACN@28211|Alphaproteobacteria,3JQZR@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Belongs to the CinA family MA20_19320 - - - - - - - - - - - CinA CMS1_k127_1082890_16 1169143.KB911037_gene3835 1.573e-24 111.0 2A4JH@1|root,30T65@2|Bacteria,1R6JU@1224|Proteobacteria,2WIH3@28216|Betaproteobacteria,1KGAA@119060|Burkholderiaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_1082890_3 1380355.JNIJ01000034_gene4324 1.896e-191 604.0 COG1167@1|root,COG1167@2|Bacteria,1MV6F@1224|Proteobacteria,2TR7I@28211|Alphaproteobacteria,3JRS7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria EK Alanine-glyoxylate amino-transferase MA20_07365 - - ko:K00375,ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 - R01939 RC00006 ko00000,ko00001,ko01000,ko03000 - - - Aminotran_1_2,GntR CMS1_k127_1082890_15 172088.AUGA01000037_gene3694 6.317e-25 106.0 2E5T0@1|root,330HC@2|Bacteria,1N7GC@1224|Proteobacteria,2UHV0@28211|Alphaproteobacteria,3K0RW@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_1082890_12 670292.JH26_09300 3.64e-47 177.0 COG0251@1|root,COG0251@2|Bacteria,1MZ5K@1224|Proteobacteria,2U9DU@28211|Alphaproteobacteria,1JVSX@119045|Methylobacteriaceae 28211|Alphaproteobacteria J PFAM Endoribonuclease L-PSP - - - - - - - - - - - - Ribonuc_L-PSP CMS1_k127_1082890_4 1380394.JADL01000013_gene697 1.273e-155 499.0 COG3386@1|root,COG3386@2|Bacteria,1MU0C@1224|Proteobacteria,2TSXG@28211|Alphaproteobacteria,2JPR9@204441|Rhodospirillales 204441|Rhodospirillales G SMP-30/Gluconolaconase/LRE-like region - - 3.1.1.17 ko:K01053 ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220 M00129 R01519,R02933,R03751 RC00537,RC00983 ko00000,ko00001,ko00002,ko01000,ko04147 - - - SGL CMS1_k127_1082890_6 1429916.X566_03700 5.924e-145 473.0 COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,2TQVX@28211|Alphaproteobacteria,3JQMI@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L FES mutY GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03575 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD,NUDIX_4 CMS1_k127_1082890_11 258594.RPA4486 8.303e-49 189.0 COG5389@1|root,COG5389@2|Bacteria,1N82D@1224|Proteobacteria,2UFA9@28211|Alphaproteobacteria,3JY8X@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF721) MA20_42435 - - - - - - - - - - - DUF721 CMS1_k127_1082890_9 991905.SL003B_3364 2.968e-65 237.0 COG1651@1|root,COG1651@2|Bacteria,1RFF4@1224|Proteobacteria,2U5BN@28211|Alphaproteobacteria,4BQHQ@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria O Thioredoxin MA20_42440 - - - - - - - - - - - Thioredoxin_4 CMS1_k127_1082890_0 1429916.X566_03715 0.0 1389.0 COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,2TRQG@28211|Alphaproteobacteria,3JUPU@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria D Required for chromosome condensation and partitioning smc - - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N CMS1_k127_1082890_1 1500301.JQMF01000007_gene1512 1.254e-202 633.0 COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1MURA@1224|Proteobacteria,2TR1F@28211|Alphaproteobacteria,4B7TE@82115|Rhizobiaceae 28211|Alphaproteobacteria P metal ion binding MA20_22850 - - - - - - - - - - - Lactamase_B,Rhodanese CMS1_k127_1082890_18 932213.SPM24T3_06468 0.0002209 47.0 2CIZN@1|root,33BAP@2|Bacteria,1NJHF@1224|Proteobacteria,1SHYB@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Superinfection immunity protein - - - - - - - - - - - - Imm_superinfect,SHOCT CMS1_k127_1082890_7 1187851.A33M_2814 2.349e-88 295.0 COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,2U6EM@28211|Alphaproteobacteria 28211|Alphaproteobacteria S LemA family MA20_42455 - - ko:K03744 - - - - ko00000 - - - LemA CMS1_k127_1082890_5 316058.RPB_4314 4.732e-145 469.0 COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,2TS3N@28211|Alphaproteobacteria,3JRCT@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O Belongs to the peptidase M48B family htpX - - ko:K03799 - M00743 - - ko00000,ko00002,ko01000,ko01002 - - - Peptidase_M48 CMS1_k127_1082890_17 936455.KI421499_gene7699 2.151e-18 86.0 COG1942@1|root,COG1942@2|Bacteria,1MZXR@1224|Proteobacteria,2UG0Q@28211|Alphaproteobacteria,3K18H@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Tautomerase enzyme MA20_05500 - 5.3.2.6 ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 M00569 R03966,R05389 RC01040,RC01355 ko00000,ko00001,ko00002,ko01000 - - - Tautomerase CMS1_k127_1082890_13 1123229.AUBC01000011_gene2373 4.426e-44 161.0 COG0503@1|root,COG0503@2|Bacteria,1MVZ6@1224|Proteobacteria,2TV7J@28211|Alphaproteobacteria,3JQWV@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis apt - 2.4.2.7 ko:K00759 ko00230,ko01100,map00230,map01100 - R00190,R01229,R04378 RC00063 ko00000,ko00001,ko01000,ko04147 - - - Pribosyltran CMS1_k127_1085850_11 1163408.UU9_06639 1.334e-14 76.0 COG0053@1|root,COG0053@2|Bacteria,1MVH8@1224|Proteobacteria,1RQ3E@1236|Gammaproteobacteria,1X42A@135614|Xanthomonadales 135614|Xanthomonadales P Co Zn Cd cation transporters catA - - - - - - - - - - - Cation_efflux CMS1_k127_1085850_8 1287276.X752_24575 4.969e-32 131.0 COG0053@1|root,COG0053@2|Bacteria,1MVH8@1224|Proteobacteria,2TVQV@28211|Alphaproteobacteria,43HC5@69277|Phyllobacteriaceae 28211|Alphaproteobacteria P cation diffusion facilitator family transporter - - - - - - - - - - - - Cation_efflux,ZT_dimer CMS1_k127_1085850_10 1429916.X566_13195 4.475e-19 94.0 COG3187@1|root,COG3187@2|Bacteria,1RGWB@1224|Proteobacteria,2U9ZH@28211|Alphaproteobacteria,3JZRF@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O META domain MA20_05910 - - - - - - - - - - - META CMS1_k127_1085850_5 1380391.JIAS01000012_gene4371 1.782e-108 363.0 COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,2TTPH@28211|Alphaproteobacteria,2JS0P@204441|Rhodospirillales 204441|Rhodospirillales Q Dienelactone hydrolase family - - 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 - R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 - - - DLH CMS1_k127_1085850_4 631454.N177_0822 6.952e-146 476.0 COG0154@1|root,COG0154@2|Bacteria,1MWRI@1224|Proteobacteria,2TTJU@28211|Alphaproteobacteria,1JPPB@119043|Rhodobiaceae 28211|Alphaproteobacteria J Amidase - - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase CMS1_k127_1085850_1 1211115.ALIQ01000243_gene3768 1.011e-187 605.0 COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,2TQNR@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q TRAP-type mannitol chloroaromatic compound transport system large permease component - - - - - - - - - - - - DctM CMS1_k127_1085850_6 1211115.ALIQ01000243_gene3767 9.914e-80 270.0 COG4665@1|root,COG4665@2|Bacteria,1RHBW@1224|Proteobacteria,2U4QB@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - - - - - - - - - - DctQ CMS1_k127_1085850_3 1120956.JHZK01000001_gene3371 2.46e-170 542.0 COG4663@1|root,COG4663@2|Bacteria,1MUXI@1224|Proteobacteria,2TQVW@28211|Alphaproteobacteria,1JPPC@119043|Rhodobiaceae 28211|Alphaproteobacteria Q Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP,TAT_signal CMS1_k127_1085850_0 1297863.APJF01000007_gene2530 1.596e-236 746.0 COG4178@1|root,COG4178@2|Bacteria,1MW09@1224|Proteobacteria,2TS9Q@28211|Alphaproteobacteria,3JQVA@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter - - - ko:K02471 ko02010,map02010 - - - ko00000,ko00001,ko02000 3.A.1.203.11,3.A.1.203.4 - - ABC_membrane_2,ABC_tran CMS1_k127_1085850_2 1417296.U879_10130 8.314e-171 557.0 COG0038@1|root,COG0038@2|Bacteria,1MV4K@1224|Proteobacteria,2TTBG@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Chloride channel - - - ko:K03281 - - - - ko00000 2.A.49 - - CBS,Voltage_CLC CMS1_k127_1085850_9 1417296.U879_10125 2.488e-22 107.0 2ECH6@1|root,336FD@2|Bacteria,1NDZP@1224|Proteobacteria,2UGSK@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_1085850_7 1120792.JAFV01000001_gene3850 3.521e-50 188.0 2DQY9@1|root,339CR@2|Bacteria,1NR8Y@1224|Proteobacteria,2U152@28211|Alphaproteobacteria,370T2@31993|Methylocystaceae 28211|Alphaproteobacteria S Bacterial protein of unknown function (Gcw_chp) - - - - - - - - - - - - Gcw_chp CMS1_k127_1088805_0 1280953.HOC_20643 5.029e-255 787.0 COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,2TQP8@28211|Alphaproteobacteria,43WVI@69657|Hyphomonadaceae 28211|Alphaproteobacteria J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis tuf GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K02358 - - - - ko00000,ko03012,ko03029,ko04147 - - - GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 CMS1_k127_1088991_0 396588.Tgr7_2267 1.477e-218 688.0 COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,1RMA5@1236|Gammaproteobacteria,1WWCQ@135613|Chromatiales 135613|Chromatiales S modulator of DNA gyrase tldD - - ko:K03568 - - - - ko00000,ko01002 - - - PmbA_TldD CMS1_k127_1095064_1 1187851.A33M_2800 2.026e-141 452.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,3FCJC@34008|Rhodovulum 28211|Alphaproteobacteria C Aldehyde dehydrogenase family gabD1 - 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh CMS1_k127_1095064_2 426117.M446_5900 6.008e-121 403.0 COG0508@1|root,COG0508@2|Bacteria,1MUGY@1224|Proteobacteria,2TRXM@28211|Alphaproteobacteria,1JQYM@119045|Methylobacteriaceae 28211|Alphaproteobacteria C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) pdhC - 1.2.4.1,2.3.1.12 ko:K00162,ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R02569,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02857,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding CMS1_k127_1095064_3 936455.KI421499_gene7117 1.305e-120 395.0 COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,2TTJV@28211|Alphaproteobacteria,3JR7H@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria CH D-isomer specific 2-hydroxyacid dehydrogenase MA20_40345 - - - - - - - - - - - 2-Hacid_dh,2-Hacid_dh_C CMS1_k127_1095064_5 1187851.A33M_1853 5.847e-50 186.0 293Y3@1|root,2ZRD4@2|Bacteria,1MW85@1224|Proteobacteria,2TR4S@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protease inhibitor Inh MA20_40350 - - - - - - - - - - - Inh CMS1_k127_1095064_4 323098.Nwi_0335 2.096e-110 361.0 COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,2TQXM@28211|Alphaproteobacteria,3JUPY@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L Belongs to the UPF0758 family radC - - ko:K03630 - - - - ko00000 - - - RadC CMS1_k127_1095064_0 1187851.A33M_2086 7.49e-154 488.0 COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,2TQTH@28211|Alphaproteobacteria,3FCNS@34008|Rhodovulum 28211|Alphaproteobacteria J Metallopeptidase family M24 map - 3.4.11.18 ko:K01265 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 CMS1_k127_1095064_6 709797.CSIRO_0599 8.101e-44 161.0 COG1489@1|root,COG1489@2|Bacteria,1MUC3@1224|Proteobacteria,2U10V@28211|Alphaproteobacteria,3K3H5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Sugar fermentation stimulation protein sfsA - - ko:K06206 - - - - ko00000 - - - SfsA CMS1_k127_1104398_5 1297865.APJD01000010_gene4893 3.261e-118 387.0 COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,2TS2D@28211|Alphaproteobacteria,3JVAJ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate panC GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R02473 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - - Pantoate_ligase CMS1_k127_1104398_0 114615.BRADO4553 2.528e-140 451.0 COG1192@1|root,COG1192@2|Bacteria,1MVKR@1224|Proteobacteria,2TRZY@28211|Alphaproteobacteria,3JUQ2@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria D ATPase MipZ mipZ - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - MipZ CMS1_k127_1104398_6 113395.AXAI01000004_gene4555 1.788e-92 310.0 COG2304@1|root,COG2304@2|Bacteria,1RA4S@1224|Proteobacteria,2U5T8@28211|Alphaproteobacteria,3JQRD@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S von Willebrand factor (vWF) type A domain - - - - - - - - - - - - - CMS1_k127_1104398_7 1187851.A33M_1017 1.532e-75 259.0 COG2214@1|root,COG2214@2|Bacteria,1PUS9@1224|Proteobacteria,2TT35@28211|Alphaproteobacteria 28211|Alphaproteobacteria O PFAM heat shock protein DnaJ domain protein MA20_36100 - - - - - - - - - - - DnaJ CMS1_k127_1104398_2 316058.RPB_2393 1.045e-124 419.0 COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,2TRCV@28211|Alphaproteobacteria,3JT9T@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Belongs to the peptidase S11 family dacA1 - 3.4.16.4 ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - Peptidase_S11,SPOR CMS1_k127_1104398_9 1168059.KB899087_gene1462 6.082e-39 149.0 COG5490@1|root,COG5490@2|Bacteria,1MZW0@1224|Proteobacteria,2UC4T@28211|Alphaproteobacteria,3EZYW@335928|Xanthobacteraceae 28211|Alphaproteobacteria S Phasin protein MA20_36110 - - - - - - - - - - - Phasin_2 CMS1_k127_1104398_1 936455.KI421499_gene2126 1.015e-133 440.0 COG4961@1|root,COG4961@2|Bacteria,1MWXU@1224|Proteobacteria,2TRQP@28211|Alphaproteobacteria,3JSKJ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria U Putative Flp pilus-assembly TadE/G-like - - - - - - - - - - - - Tad,VWA CMS1_k127_1104398_4 1297863.APJF01000029_gene1438 7.696e-119 396.0 COG4961@1|root,COG4961@2|Bacteria,1MWXU@1224|Proteobacteria,2TRQP@28211|Alphaproteobacteria,3JSKJ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria U Putative Flp pilus-assembly TadE/G-like - - - - - - - - - - - - Tad,VWA CMS1_k127_1104398_3 443598.AUFA01000012_gene4903 3.167e-123 410.0 COG4961@1|root,COG4961@2|Bacteria,1MWXU@1224|Proteobacteria,2TRQP@28211|Alphaproteobacteria,3JSKJ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria U Putative Flp pilus-assembly TadE/G-like - - - - - - - - - - - - Tad,VWA CMS1_k127_1104398_8 318996.AXAZ01000019_gene1703 1.249e-60 216.0 COG4961@1|root,COG4961@2|Bacteria,1MWXU@1224|Proteobacteria,2TRQP@28211|Alphaproteobacteria,3JSKJ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria U Putative Flp pilus-assembly TadE/G-like - - - - - - - - - - - - Tad,VWA CMS1_k127_1104427_10 1245469.S58_70290 4.21e-13 70.0 COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,2TRDA@28211|Alphaproteobacteria,3JSY5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) aroB - 2.7.1.71,4.2.3.4 ko:K01735,ko:K13829 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412,R03083 RC00002,RC00078,RC00847 ko00000,ko00001,ko00002,ko01000 - - - DHQ_synthase,SKI CMS1_k127_1104427_8 1187851.A33M_3874 2.507e-62 226.0 COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,2U76C@28211|Alphaproteobacteria,3FD62@34008|Rhodovulum 28211|Alphaproteobacteria F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate aroK GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - SKI CMS1_k127_1104427_11 196490.AUEZ01000040_gene6040 9.326e-12 75.0 2EGFM@1|root,33A7M@2|Bacteria,1N8GQ@1224|Proteobacteria,2UG7D@28211|Alphaproteobacteria,3K0XF@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - MA20_39815 - - - - - - - - - - - - CMS1_k127_1104427_4 1187851.A33M_3879 1.239e-124 407.0 COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,2TRAA@28211|Alphaproteobacteria,3FCXV@34008|Rhodovulum 28211|Alphaproteobacteria L Phage integrase, N-terminal SAM-like domain xerD - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase CMS1_k127_1104427_2 709797.CSIRO_0654 1.893e-154 493.0 COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,2TR6V@28211|Alphaproteobacteria,3JVAA@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA accA - 2.1.3.15,6.4.1.2 ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - ACCA CMS1_k127_1104427_3 709797.CSIRO_0655 3.243e-137 453.0 COG3034@1|root,COG3034@2|Bacteria,1MXY6@1224|Proteobacteria,2TS2U@28211|Alphaproteobacteria,3JTHD@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria NU ErfK YbiS YcfS YnhG family protein - - - - - - - - - - - - YkuD CMS1_k127_1104427_9 652103.Rpdx1_1723 1.194e-28 117.0 COG2827@1|root,COG2827@2|Bacteria,1N2X6@1224|Proteobacteria,2UCV1@28211|Alphaproteobacteria,3K0NR@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L Excinuclease ABC, C subunit - - - ko:K07461 - - - - ko00000 - - - GIY-YIG CMS1_k127_1104427_0 1187851.A33M_3724 0.0 1513.0 COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,2TTBF@28211|Alphaproteobacteria,3FCG5@34008|Rhodovulum 28211|Alphaproteobacteria U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015627,GO:0015628,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:0098776,GO:1901265,GO:1901363,GO:1904680 - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW CMS1_k127_1104427_6 639283.Snov_2789 7.593e-79 289.0 COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,2TVQD@28211|Alphaproteobacteria,3EZ6E@335928|Xanthobacteraceae 28211|Alphaproteobacteria O PPIC-type PPIASE domain ppiC - 5.2.1.8 ko:K01802,ko:K03769 - - - - ko00000,ko01000,ko03110 - - - Rotamase,Rotamase_3 CMS1_k127_1104427_1 335659.S23_05980 6.645e-197 622.0 COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,2TS98@28211|Alphaproteobacteria,3JT8Y@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate argJ GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259,R02282 RC00004,RC00064 ko00000,ko00001,ko00002,ko01000 - - - ArgJ CMS1_k127_1104427_7 1038859.AXAU01000004_gene4490 1.493e-66 229.0 COG0494@1|root,COG0494@2|Bacteria,1RCZM@1224|Proteobacteria,2U7A4@28211|Alphaproteobacteria,3JY6Z@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L NUDIX domain mutT GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - Acetyltransf_3,NUDIX,NUDIX_4 CMS1_k127_1104427_12 114615.BRADO5643 3.253e-09 59.0 COG3847@1|root,COG3847@2|Bacteria,1NGVU@1224|Proteobacteria,2UJE8@28211|Alphaproteobacteria 28211|Alphaproteobacteria U Flp Fap pilin component - - - ko:K02651 ko04112,map04112 - - - ko00000,ko00001,ko02035,ko02044 - - - Flp_Fap CMS1_k127_1104427_5 1038858.AXBA01000012_gene1785 6.728e-91 304.0 COG0500@1|root,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,2TRFS@28211|Alphaproteobacteria,3EY58@335928|Xanthobacteraceae 28211|Alphaproteobacteria Q Methyltransferase domain bioC - - - - - - - - - - - Methyltransf_11,Methyltransf_23 CMS1_k127_1142307_3 1040989.AWZU01000006_gene558 8.459e-70 237.0 COG1692@1|root,COG1692@2|Bacteria,1MW12@1224|Proteobacteria,2TS4S@28211|Alphaproteobacteria,3JQZG@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S YmdB-like protein MA20_17970 - - ko:K09769 - - - - ko00000 - - - YmdB CMS1_k127_1142307_4 1038859.AXAU01000012_gene4219 1.251e-63 224.0 COG0212@1|root,COG0212@2|Bacteria,1MZG0@1224|Proteobacteria,2UBY4@28211|Alphaproteobacteria,3JTHS@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family MA20_17975 - 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 - R02301 RC00183 ko00000,ko00001,ko01000 - - - 5-FTHF_cyc-lig CMS1_k127_1142307_5 1502851.FG93_05458 9.126e-42 161.0 COG2050@1|root,COG2050@2|Bacteria,1RGVD@1224|Proteobacteria,2U9MH@28211|Alphaproteobacteria,3JY97@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria Q Thioesterase superfamily - - - - - - - - - - - - 4HBT CMS1_k127_1142307_6 1380355.JNIJ01000005_gene2628 1.157e-34 137.0 COG3027@1|root,COG3027@2|Bacteria,1N8NY@1224|Proteobacteria,2UCRX@28211|Alphaproteobacteria,3JZUM@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division MA20_17980 - - ko:K09888 - - - - ko00000,ko03036 - - - ZapA CMS1_k127_1142307_7 316056.RPC_4765 3.797e-21 95.0 2EA88@1|root,334CR@2|Bacteria,1N16P@1224|Proteobacteria,2U9E9@28211|Alphaproteobacteria,3K01M@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Domain of unknown function (DUF4164) MA20_17985 - - - - - - - - - - - DUF4164 CMS1_k127_1142307_0 709797.CSIRO_0506 3.154e-319 994.0 COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,2TQUX@28211|Alphaproteobacteria,3JUC9@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate tktA - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C,Transketolase_N CMS1_k127_1142307_1 196490.AUEZ01000009_gene5326 1.815e-192 604.0 COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,2TR6E@28211|Alphaproteobacteria,3JSED@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gapA - 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N CMS1_k127_1142307_2 1187851.A33M_1485 2.401e-188 596.0 COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,2TSKQ@28211|Alphaproteobacteria,3FCSM@34008|Rhodovulum 28211|Alphaproteobacteria F Phosphoglycerate kinase pgk GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.2.3 ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01512 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGK CMS1_k127_1144730_0 670292.JH26_14110 6.364e-126 408.0 COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,2TQZ6@28211|Alphaproteobacteria,1JUIC@119045|Methylobacteriaceae 28211|Alphaproteobacteria EQ PFAM Hydantoinase oxoprolinase hyuA - 3.5.2.14 ko:K01473 ko00330,ko01100,map00330,map01100 - R03187 RC00632 ko00000,ko00001,ko01000 - - - Hydant_A_N,Hydantoinase_A,Hydantoinase_B CMS1_k127_1144730_1 426117.M446_1936 2.645e-94 315.0 COG1335@1|root,COG1335@2|Bacteria,1MV0W@1224|Proteobacteria,2TUVZ@28211|Alphaproteobacteria,1JSXJ@119045|Methylobacteriaceae 28211|Alphaproteobacteria Q PFAM isochorismatase hydrolase - - 3.5.1.110 ko:K09020 ko00240,ko01100,map00240,map01100 - R09947,R09980 RC02737,RC02738 ko00000,ko00001,ko01000 - - - Glyoxalase,Isochorismatase CMS1_k127_1144730_2 1123060.JONP01000006_gene4742 2.711e-89 301.0 COG1053@1|root,COG1053@2|Bacteria,1MX5A@1224|Proteobacteria,2TV7T@28211|Alphaproteobacteria 28211|Alphaproteobacteria C COG1053 Succinate dehydrogenase fumarate reductase flavoprotein subunit - - 1.3.5.4 ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00150,M00173 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2 CMS1_k127_1153336_0 331869.BAL199_01069 2.664e-265 824.0 COG2936@1|root,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,2TU0R@28211|Alphaproteobacteria,4BRPC@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria S X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain - - - ko:K06978 - - - - ko00000 - - - PepX_C,Peptidase_S15 CMS1_k127_1153336_2 314278.NB231_00250 5.586e-92 313.0 COG1181@1|root,COG1181@2|Bacteria,1N4F5@1224|Proteobacteria,1SKJ8@1236|Gammaproteobacteria,1X0FH@135613|Chromatiales 135613|Chromatiales F Belongs to the D-alanine--D-alanine ligase family - - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C CMS1_k127_1153336_1 1038859.AXAU01000030_gene6770 1.563e-169 544.0 COG0428@1|root,COG0428@2|Bacteria,1NR95@1224|Proteobacteria,2TS59@28211|Alphaproteobacteria 28211|Alphaproteobacteria P transporter - - - - - - - - - - - - Zip CMS1_k127_1153336_3 420324.KI912074_gene5933 2.696e-73 248.0 COG2132@1|root,COG2132@2|Bacteria,1MXT2@1224|Proteobacteria,2VF0D@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q Multicopper oxidase - - - - - - - - - - - - Cu-oxidase_2,Cu-oxidase_3 CMS1_k127_115670_1 1205908.AKXW01000007_gene3230 5.095e-39 149.0 COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,1S233@1236|Gammaproteobacteria,1XWXN@135623|Vibrionales 135623|Vibrionales F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA dut - 3.6.1.23 ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00053 R02100,R11896 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 - - - dUTPase CMS1_k127_115670_0 1122194.AUHU01000009_gene3185 7.746e-144 466.0 COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,1RMKQ@1236|Gammaproteobacteria,464IR@72275|Alteromonadaceae 1236|Gammaproteobacteria H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine coaBC GO:0000166,GO:0003674,GO:0003824,GO:0004632,GO:0004633,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0010181,GO:0015936,GO:0015937,GO:0016829,GO:0016830,GO:0016831,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032553,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.1.1.36,6.3.2.5 ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 - - iEC042_1314.EC042_3945,iECUMN_1333.ECUMN_4154,iJN746.PP_5285,iSBO_1134.SBO_3641 DFP,Flavoprotein CMS1_k127_1157129_3 1040989.AWZU01000023_gene4895 1.226e-09 64.0 29CUQ@1|root,2ZZSV@2|Bacteria,1N1EJ@1224|Proteobacteria,2UE14@28211|Alphaproteobacteria,3K0KF@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_1157129_2 189753.AXAS01000011_gene7551 1.972e-54 203.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2URQN@28211|Alphaproteobacteria,3K6JB@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - - - - - - - - - - ABC_sub_bind CMS1_k127_1157129_1 189753.AXAS01000041_gene2534 1.807e-112 373.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind CMS1_k127_1157129_0 1298867.AUES01000016_gene3879 0.0 1027.0 COG2203@1|root,COG4191@1|root,COG5002@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,COG5002@2|Bacteria,1RCM9@1224|Proteobacteria,2TTJ0@28211|Alphaproteobacteria,3K6MV@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Cache domain - - - - - - - - - - - - GAF,GAF_2,HAMP,HATPase_c,HisKA,dCache_1 CMS1_k127_1158140_3 397945.Aave_3016 1.254e-81 276.0 COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,2VHV1@28216|Betaproteobacteria,4ABAB@80864|Comamonadaceae 28216|Betaproteobacteria C PFAM aldo keto reductase - - 1.1.1.91 ko:K05882 - - - - ko00000,ko01000 - - - Aldo_ket_red CMS1_k127_1158140_2 1380355.JNIJ01000004_gene2825 4.032e-194 611.0 COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,2TR4R@28211|Alphaproteobacteria,3JTAE@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Thiamine pyrophosphate enzyme, C-terminal TPP binding domain MA20_01040 - 1.2.7.11,1.2.7.3 ko:K00175 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - PFO_beta_C,TPP_enzyme_C CMS1_k127_1158140_0 196490.AUEZ01000019_gene553 0.0 1073.0 COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,2TU21@28211|Alphaproteobacteria,3JUZI@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg MA20_01045 - 1.2.7.11,1.2.7.3 ko:K00174 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - PFOR_II,POR,POR_N CMS1_k127_1158140_1 595537.Varpa_2455 2.19e-311 964.0 COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1MU2H@1224|Proteobacteria,2VM9R@28216|Betaproteobacteria,4AD4V@80864|Comamonadaceae 28216|Betaproteobacteria C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster korC - - - - - - - - - - - Fer4_20,Fer4_7,Pyr_redox_2,Pyr_redox_3 CMS1_k127_1159028_4 1380350.JIAP01000013_gene859 2.963e-63 224.0 COG0491@1|root,COG0491@2|Bacteria,1MY6G@1224|Proteobacteria,2TTBX@28211|Alphaproteobacteria,43JIG@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B CMS1_k127_1159028_6 1230343.CANP01000048_gene3714 7.138e-05 47.0 2DHAH@1|root,2ZYZJ@2|Bacteria,1QBV6@1224|Proteobacteria,1T7FX@1236|Gammaproteobacteria,1JFBW@118969|Legionellales 118969|Legionellales S Protein of unknown function (DUF3309) - - - - - - - - - - - - DUF3309 CMS1_k127_1159028_2 1187851.A33M_0556 5.101e-104 346.0 COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,2TSTN@28211|Alphaproteobacteria,3FCWY@34008|Rhodovulum 28211|Alphaproteobacteria K ParB-like nuclease domain parB - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc CMS1_k127_1159028_1 1429916.X566_09140 2.27e-135 438.0 COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,2TSWH@28211|Alphaproteobacteria,3JRXN@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria D Cellulose biosynthesis protein BcsQ parA - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 CMS1_k127_1159028_3 1429916.X566_09135 2.707e-68 241.0 COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,2U9T9@28211|Alphaproteobacteria,3JQQP@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Specifically methylates the N7 position of guanine in position 527 of 16S rRNA rsmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 ko:K03501 - - - - ko00000,ko01000,ko03009,ko03036 - - - GidB CMS1_k127_1159028_0 1187851.A33M_0559 2.866e-307 952.0 COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,2TRJS@28211|Alphaproteobacteria,3FCR9@34008|Rhodovulum 28211|Alphaproteobacteria D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 gidA GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - ko:K03495 - - R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 - - - GIDA,GIDA_assoc CMS1_k127_1159028_5 402881.Plav_1272 1.036e-12 67.0 COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,2TQZW@28211|Alphaproteobacteria,1JN2J@119043|Rhodobiaceae 28211|Alphaproteobacteria J Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 mnmE - - ko:K03650 - - R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 - - - MMR_HSR1,MnmE_helical,TrmE_N CMS1_k127_1166425_0 1510531.JQJJ01000012_gene1465 1.406e-129 419.0 COG0834@1|root,COG0834@2|Bacteria,1MV5D@1224|Proteobacteria,2TSRF@28211|Alphaproteobacteria,3JTG4@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria ET Belongs to the bacterial solute-binding protein 3 family MA20_30070 - - ko:K09969 ko02010,map02010 M00232 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.18,3.A.1.3.7,3.A.1.3.8 - - SBP_bac_3 CMS1_k127_1166425_1 1380355.JNIJ01000011_gene979 1.622e-106 350.0 COG0477@1|root,COG2814@2|Bacteria,1MWFH@1224|Proteobacteria,2TR0R@28211|Alphaproteobacteria,3JVQA@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria EGP Major Facilitator Superfamily - - - ko:K08224 - - - - ko00000,ko02000 2.A.1.36 - - MFS_1,Sugar_tr CMS1_k127_1167014_2 177437.HRM2_12250 1.961e-22 97.0 COG0834@1|root,COG0834@2|Bacteria,1MV3Q@1224|Proteobacteria,42MKG@68525|delta/epsilon subdivisions,2WPID@28221|Deltaproteobacteria,2MMR6@213118|Desulfobacterales 28221|Deltaproteobacteria ET Bacterial periplasmic substrate-binding proteins - - - ko:K02030,ko:K10022 ko02010,map02010 M00235,M00236 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.11 - - SBP_bac_3 CMS1_k127_1167014_1 536019.Mesop_4847 5.688e-45 172.0 COG4122@1|root,COG4122@2|Bacteria,1RF3H@1224|Proteobacteria,2U84F@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Macrocin-O-methyltransferase (TylF) - - - - - - - - - - - - Methyltransf_24,TylF CMS1_k127_1167014_0 493475.GARC_4612 8.94e-76 266.0 COG4798@1|root,COG4798@2|Bacteria,1NNHX@1224|Proteobacteria,1RN1A@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Methyltransferase - - - - - - - - - - - - - CMS1_k127_1167014_3 1333998.M2A_2759 4.677e-14 75.0 COG4731@1|root,COG4731@2|Bacteria,1RHT2@1224|Proteobacteria,2TZZZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Uncharacterized protein conserved in bacteria (DUF2147) - - - - - - - - - - - - - CMS1_k127_1191327_2 113395.AXAI01000011_gene6515 7.76e-52 188.0 COG1749@1|root,COG1749@2|Bacteria,1MU5J@1224|Proteobacteria,2TSF2@28211|Alphaproteobacteria,3JR44@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria N flagellar basal body flgE - - ko:K02390 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlaE,Flg_bb_rod,Flg_bbr_C CMS1_k127_1191327_0 1040989.AWZU01000004_gene7073 2.838e-193 628.0 COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1MVMG@1224|Proteobacteria,2TRVB@28211|Alphaproteobacteria,3K2NJ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O Glycosyl transferase family 41 - - - - - - - - - - - - Glyco_transf_41,TPR_11,TPR_16,TPR_2,TPR_8 CMS1_k127_1191327_1 631454.N177_0490 4.658e-67 233.0 COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,2U70T@28211|Alphaproteobacteria,1JP1B@119043|Rhodobiaceae 28211|Alphaproteobacteria O SelR domain msrB1 - 1.8.4.12 ko:K07305 - - - - ko00000,ko01000 - - - SelR CMS1_k127_1199831_0 391596.PBAL39_22625 1.758e-63 228.0 COG2133@1|root,COG2133@2|Bacteria,4NF0B@976|Bacteroidetes,1IPCH@117747|Sphingobacteriia 976|Bacteroidetes G Glucose / Sorbosone dehydrogenase - - - - - - - - - - - - CBM_6,GSDH,Ig_2,Malectin,PKD,VCBS,fn3 CMS1_k127_1199831_2 1117379.BABA_26071 1.645e-07 59.0 COG2010@1|root,COG4993@1|root,COG2010@2|Bacteria,COG4993@2|Bacteria,1V091@1239|Firmicutes,4HCPE@91061|Bacilli,1ZFCQ@1386|Bacillus 91061|Bacilli CG COG4993 Glucose dehydrogenase - - - - - - - - - - - - Cytochrome_CBB3,PQQ,PQQ_2 CMS1_k127_1199831_3 1550091.JROE01000002_gene1139 1.245e-06 57.0 2DZQQ@1|root,32VGE@2|Bacteria,4NTQG@976|Bacteroidetes,1IUJT@117747|Sphingobacteriia 976|Bacteroidetes S Transmembrane family 220, helix - - - - - - - - - - - - TMEM220 CMS1_k127_1199831_1 1411123.JQNH01000001_gene689 1.02e-30 128.0 COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,2U3RT@28211|Alphaproteobacteria 28211|Alphaproteobacteria E 3-dehydroquinate synthase - - 4.2.3.4 ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03083 RC00847 ko00000,ko00001,ko00002,ko01000 - - - DHQ_synthase CMS1_k127_1207016_1 1163617.SCD_n00008 7.956e-20 90.0 COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,2VIZJ@28216|Betaproteobacteria 28216|Betaproteobacteria S PFAM Peptidoglycan-binding LysM - - - - - - - - - - - - LysM CMS1_k127_1207016_0 1304883.KI912532_gene786 2.703e-116 385.0 COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,2VH3W@28216|Betaproteobacteria,2KUP7@206389|Rhodocyclales 206389|Rhodocyclales LU Rossmann fold nucleotide-binding protein involved in DNA uptake - - - ko:K04096 - - - - ko00000 - - - DNA_processg_A CMS1_k127_1207016_2 123899.JPQP01000003_gene1285 9.392e-10 61.0 COG2922@1|root,COG2922@2|Bacteria,1RD5F@1224|Proteobacteria,2VRJF@28216|Betaproteobacteria,3T3WZ@506|Alcaligenaceae 28216|Betaproteobacteria S Belongs to the Smg family smg - - ko:K03747 - - - - ko00000 - - - DUF494 CMS1_k127_1210405_3 479433.Caci_5582 1.646e-119 396.0 COG0677@1|root,COG0677@2|Bacteria,2GK5K@201174|Actinobacteria 201174|Actinobacteria M Belongs to the UDP-glucose GDP-mannose dehydrogenase family - - 1.1.1.336 ko:K02472 ko00520,ko05111,map00520,map05111 - R03317 RC00291 ko00000,ko00001,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N CMS1_k127_1210405_4 167542.P9515_07281 1.774e-50 188.0 COG1215@1|root,COG1215@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups - - 2.4.1.83 ko:K00721 ko00510,ko01100,map00510,map01100 - R01009 RC00005 ko00000,ko00001,ko01000,ko01003 - GT2 - Glycos_transf_2 CMS1_k127_1210405_6 189753.AXAS01000029_gene6926 2.201e-40 156.0 COG0494@1|root,COG0494@2|Bacteria,1Q4Q4@1224|Proteobacteria,2VB5B@28211|Alphaproteobacteria,3K5QY@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L NUDIX domain - - - - - - - - - - - - NUDIX CMS1_k127_1210405_0 288000.BBta_4023 1.563e-228 714.0 COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,2TQXI@28211|Alphaproteobacteria,3JSGC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E 5-aminolevulinic acid synthase hemA - 2.3.1.37 ko:K00643 ko00260,ko00860,ko01100,ko01110,map00260,map00860,map01100,map01110 - R00830 RC00004,RC02815 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 CMS1_k127_1210405_1 420324.KI912084_gene7392 2.326e-141 469.0 COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria 28211|Alphaproteobacteria T Adenylate cyclase - - - - - - - - - - - - Guanylate_cyc,Trans_reg_C CMS1_k127_1210405_2 1038859.AXAU01000001_gene3578 2.874e-128 414.0 COG1028@1|root,COG1028@2|Bacteria,1NCD3@1224|Proteobacteria,2TTFD@28211|Alphaproteobacteria,3JU73@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria IQ Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short_C2 CMS1_k127_1210405_5 1298867.AUES01000021_gene3282 2.565e-49 186.0 COG3180@1|root,COG3180@2|Bacteria,1MUFS@1224|Proteobacteria,2TUUX@28211|Alphaproteobacteria,3JRDZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Transition state regulatory protein AbrB MA20_20750 - - ko:K07120 - - - - ko00000 - - - AbrB CMS1_k127_1213543_4 1038858.AXBA01000012_gene1785 2.371e-24 106.0 COG0500@1|root,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,2TRFS@28211|Alphaproteobacteria,3EY58@335928|Xanthobacteraceae 28211|Alphaproteobacteria Q Methyltransferase domain bioC - - - - - - - - - - - Methyltransf_11,Methyltransf_23 CMS1_k127_1213543_1 709797.CSIRO_0662 3.1e-106 351.0 COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,2TV7G@28211|Alphaproteobacteria,3JW65@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Phosphoribosyl transferase domain comF - - - - - - - - - - - Pribosyltran CMS1_k127_1213543_3 1380367.JIBC01000005_gene3348 5.786e-27 120.0 COG0695@1|root,COG0695@2|Bacteria,1N72P@1224|Proteobacteria,2UFM1@28211|Alphaproteobacteria,3ZXTH@60136|Sulfitobacter 28211|Alphaproteobacteria O Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins grxC - - ko:K03676 - - - - ko00000,ko03110 - - - Glutaredoxin CMS1_k127_1213543_0 652103.Rpdx1_0679 6.611e-126 409.0 COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,2TRGZ@28211|Alphaproteobacteria,3JQX4@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Carbon-nitrogen hydrolase MA20_39720 - - ko:K11206 - - - - ko00000,ko01000 - - - CN_hydrolase CMS1_k127_1213543_2 1038860.AXAP01000016_gene2122 2.592e-56 203.0 COG5319@1|root,COG5319@2|Bacteria,1MZN2@1224|Proteobacteria,2UBTA@28211|Alphaproteobacteria,3JY8M@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF1178) MA20_39715 - - - - - - - - - - - DUF1178 CMS1_k127_1213543_5 189753.AXAS01000018_gene3295 5.788e-13 69.0 COG0697@1|root,COG0697@2|Bacteria,1PHRI@1224|Proteobacteria,2TUAQ@28211|Alphaproteobacteria,3JT9V@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria EG EamA-like transporter family MA20_39710 - - - - - - - - - - - EamA CMS1_k127_1214648_6 318996.AXAZ01000058_gene1233 6.502e-31 126.0 COG2960@1|root,COG2960@2|Bacteria,1N725@1224|Proteobacteria,2UFEP@28211|Alphaproteobacteria,3K0BI@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Membrane fusogenic activity MA20_05375 - - ko:K09806 - - - - ko00000 - - - BMFP CMS1_k127_1214648_3 1187851.A33M_0884 3.872e-83 283.0 COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,2U5P0@28211|Alphaproteobacteria,3FD8E@34008|Rhodovulum 28211|Alphaproteobacteria J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ctc GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02897 ko03010,map03010 M00178 - - ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L25p,Ribosomal_TL5_C CMS1_k127_1214648_2 666684.AfiDRAFT_2590 1.635e-87 293.0 COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,2TT6Q@28211|Alphaproteobacteria,3JSPW@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis pth GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 ko:K01056 - - - - ko00000,ko01000,ko03012 - - - Pept_tRNA_hydro CMS1_k127_1214648_0 1187851.A33M_0880 2.633e-187 589.0 COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,2TRAD@28211|Alphaproteobacteria,3FCGB@34008|Rhodovulum 28211|Alphaproteobacteria J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner ychF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - ko:K06942 - - - - ko00000,ko03009 - - - MMR_HSR1,YchF-GTPase_C CMS1_k127_1214648_4 438753.AZC_4151 4.496e-49 183.0 COG2030@1|root,COG2030@2|Bacteria,1RIBV@1224|Proteobacteria,2U9QR@28211|Alphaproteobacteria,3EZPC@335928|Xanthobacteraceae 28211|Alphaproteobacteria I MaoC like domain MA20_05350 - - - - - - - - - - - MaoC_dehydratas CMS1_k127_1214648_5 438753.AZC_4152 5.606e-47 177.0 COG2030@1|root,COG2030@2|Bacteria,1RIS6@1224|Proteobacteria,2UBEJ@28211|Alphaproteobacteria,3F29N@335928|Xanthobacteraceae 28211|Alphaproteobacteria I N-terminal half of MaoC dehydratase - - - - - - - - - - - - MaoC_dehydratas CMS1_k127_1214648_9 1187851.A33M_2791 9.234e-22 99.0 2DEHC@1|root,2ZN03@2|Bacteria,1P9RK@1224|Proteobacteria,2UX5E@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_1214648_12 1230476.C207_07051 5.461e-07 53.0 2BP8N@1|root,32I07@2|Bacteria,1NAZD@1224|Proteobacteria,2UGSV@28211|Alphaproteobacteria,3K0WU@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF3072) - - - - - - - - - - - - DUF3072 CMS1_k127_1214648_11 1411123.JQNH01000001_gene1323 1.844e-07 59.0 2EGV5@1|root,33AMB@2|Bacteria,1RESC@1224|Proteobacteria,2U7A9@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF1236) - - - - - - - - - - - - DUF1236 CMS1_k127_1214648_8 1187851.A33M_2200 1.067e-22 103.0 2FCGW@1|root,344KB@2|Bacteria,1RB9V@1224|Proteobacteria,2U6BG@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - MA20_05335 - - - - - - - - - - - - CMS1_k127_1214648_10 443598.AUFA01000008_gene4084 1.753e-21 106.0 2ETDR@1|root,33KXI@2|Bacteria,1N8C5@1224|Proteobacteria,2U178@28211|Alphaproteobacteria,3JSQ5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_1214648_7 258594.RPA2332 2.281e-28 124.0 COG0797@1|root,COG1525@1|root,COG0797@2|Bacteria,COG1525@2|Bacteria,1N145@1224|Proteobacteria,2UCUE@28211|Alphaproteobacteria,3K53S@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria LM Rare lipoprotein A - - - - - - - - - - - - DPBB_1,SNase CMS1_k127_1214648_1 717785.HYPMC_0271 5.572e-104 340.0 COG0402@1|root,COG0402@2|Bacteria,1MVMR@1224|Proteobacteria,2U0AM@28211|Alphaproteobacteria 28211|Alphaproteobacteria F Amidohydrolase family - - 3.5.2.18 ko:K15358 ko00760,ko01120,map00760,map01120 - R07984 RC01933 ko00000,ko00001,ko01000 - - - Amidohydro_1 CMS1_k127_1215821_0 1380355.JNIJ01000021_gene3688 6.779e-320 993.0 COG1028@1|root,COG3347@1|root,COG1028@2|Bacteria,COG3347@2|Bacteria,1MWSB@1224|Proteobacteria,2TSSM@28211|Alphaproteobacteria,3JWB4@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria IQ Class II Aldolase and Adducin N-terminal domain - - - - - - - - - - - - Aldolase_II,adh_short,adh_short_C2 CMS1_k127_1215821_1 1304878.AUGD01000002_gene1751 7.403e-05 48.0 COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,2TRX2@28211|Alphaproteobacteria,3JSGG@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs rne - 3.1.26.12 ko:K08300 ko03018,map03018 M00394 - - ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 - - - RNase_E_G,S1 CMS1_k127_1216648_1 367336.OM2255_12557 5.113e-41 155.0 COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,2TRUM@28211|Alphaproteobacteria 28211|Alphaproteobacteria E aminopeptidase N pepN GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0016020,GO:0016787,GO:0019538,GO:0033218,GO:0042277,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - DUF3458,DUF3458_C,Peptidase_M1 CMS1_k127_1216648_0 1123360.thalar_00737 1.128e-190 603.0 COG2225@1|root,COG2225@2|Bacteria,1MVEV@1224|Proteobacteria,2TS9R@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA glcB - 2.3.3.9 ko:K01638 ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200 M00012 R00472 RC00004,RC00308,RC02747 ko00000,ko00001,ko00002,ko01000 - - - Malate_synthase CMS1_k127_1220278_1 1187851.A33M_2300 2.304e-98 325.0 COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,2TRSU@28211|Alphaproteobacteria,3FCQ2@34008|Rhodovulum 28211|Alphaproteobacteria J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX - 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 - - - tRNA-synt_1c CMS1_k127_1220278_0 78245.Xaut_4425 5.607e-231 723.0 COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,2TS63@28211|Alphaproteobacteria,3EY7W@335928|Xanthobacteraceae 28211|Alphaproteobacteria C Citrate synthase, C-terminal domain gltA - 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt CMS1_k127_1223314_3 1380394.JADL01000001_gene2539 2.478e-106 353.0 COG0607@1|root,COG2897@1|root,COG0607@2|Bacteria,COG2897@2|Bacteria,1MU3V@1224|Proteobacteria,2TSGP@28211|Alphaproteobacteria,2JR05@204441|Rhodospirillales 204441|Rhodospirillales P Rhodanese Homology Domain - - - - - - - - - - - - Rhodanese CMS1_k127_1223314_10 331869.BAL199_27341 4.108e-55 198.0 2C02K@1|root,32R69@2|Bacteria,1RK2Q@1224|Proteobacteria,2U9PI@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_1223314_7 1187851.A33M_0612 1.297e-68 239.0 COG1670@1|root,COG1670@2|Bacteria,1N6Q1@1224|Proteobacteria,2UG72@28211|Alphaproteobacteria,3FE01@34008|Rhodovulum 28211|Alphaproteobacteria J Acetyltransferase (GNAT) domain MA20_44020 - - - - - - - - - - - Acetyltransf_3 CMS1_k127_1223314_13 1187851.A33M_0611 7.173e-38 144.0 COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,2UBUX@28211|Alphaproteobacteria,3FDDK@34008|Rhodovulum 28211|Alphaproteobacteria J Ribosomal L27 protein rpmA GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02899 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27 CMS1_k127_1223314_12 398525.KB900701_gene1808 1.358e-46 174.0 COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,2UBT3@28211|Alphaproteobacteria,3JZ0N@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J This protein binds to 23S rRNA in the presence of protein L20 rplU GO:0003674,GO:0003735,GO:0005198 - ko:K02888 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - HHH_5,Ribosomal_L21p CMS1_k127_1223314_9 1532558.JL39_17590 1.519e-59 222.0 COG2358@1|root,COG2358@2|Bacteria,1R8QD@1224|Proteobacteria,2U7M9@28211|Alphaproteobacteria,4BGNX@82115|Rhizobiaceae 28211|Alphaproteobacteria S NMT1-like family - - - ko:K07080 - - - - ko00000 - - - NMT1_3 CMS1_k127_1223314_0 935840.JAEQ01000016_gene2217 3.018e-195 629.0 COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,2TQY9@28211|Alphaproteobacteria,43I4Z@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Tripartite ATP-independent periplasmic transporter, DctM component - - - - - - - - - - - - DctM CMS1_k127_1223314_1 1537715.JQFJ01000002_gene881 7.23e-135 438.0 COG2159@1|root,COG2159@2|Bacteria,1R5PG@1224|Proteobacteria,2U4X1@28211|Alphaproteobacteria,2K9G4@204457|Sphingomonadales 204457|Sphingomonadales S Amidohydrolase - - 4.1.1.45 ko:K03392 ko00380,ko01100,map00380,map01100 M00038 R04323 RC00779 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_2 CMS1_k127_1223314_14 316058.RPB_1461 4.916e-22 96.0 2EGMT@1|root,33ADY@2|Bacteria,1NH3I@1224|Proteobacteria 1224|Proteobacteria S Phospholipase_D-nuclease N-terminal IV01_13290 - - - - - - - - - - - PLDc_N CMS1_k127_1223314_6 205918.Psyr_2051 1.529e-73 255.0 COG0745@1|root,COG0745@2|Bacteria,1MWZ5@1224|Proteobacteria,1RNY2@1236|Gammaproteobacteria,1Z6E6@136849|Pseudomonas syringae group 1236|Gammaproteobacteria K KDP operon transcriptional regulatory protein KdpE kdpE - - ko:K07667 ko02020,ko02024,map02020,map02024 M00454 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C CMS1_k127_1223314_5 1230476.C207_05377 1.588e-100 351.0 COG0642@1|root,COG2205@2|Bacteria,1NC1Z@1224|Proteobacteria,2U2BU@28211|Alphaproteobacteria,3JXGD@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Domain of unknown function (DUF4118) - - - - - - - - - - - - DUF4118,HATPase_c,HisKA CMS1_k127_1223314_15 622637.KE124774_gene2573 7.518e-12 74.0 COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,36XJI@31993|Methylocystaceae 28211|Alphaproteobacteria L Recombinase zinc beta ribbon domain - - - - - - - - - - - - Recombinase,Resolvase,Zn_ribbon_recom CMS1_k127_1223314_11 1230476.C207_05959 3.816e-53 196.0 COG3672@1|root,COG3672@2|Bacteria,1RDQS@1224|Proteobacteria,2TTZT@28211|Alphaproteobacteria,3JVGR@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Bacterial transglutaminase-like cysteine proteinase BTLCP - - - - - - - - - - - - Peptidase_C93 CMS1_k127_1223314_8 1336243.JAEA01000005_gene1447 6.481e-62 219.0 COG0664@1|root,COG0664@2|Bacteria,1Q93V@1224|Proteobacteria,2TTEY@28211|Alphaproteobacteria,1JTPF@119045|Methylobacteriaceae 28211|Alphaproteobacteria T PFAM Cyclic nucleotide-binding MA20_09210 - - - - - - - - - - - Imp-YgjV,cNMP_binding CMS1_k127_1223314_4 709797.CSIRO_2935 5.053e-103 342.0 COG1235@1|root,COG1235@2|Bacteria,1NW4Z@1224|Proteobacteria,2U14Z@28211|Alphaproteobacteria,3JSHK@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Beta-lactamase superfamily domain - - - - - - - - - - - - Lactamase_B_2 CMS1_k127_1223314_2 1040989.AWZU01000029_gene4361 1.174e-111 372.0 COG2905@1|root,COG2905@2|Bacteria,1QUQR@1224|Proteobacteria,2TWQS@28211|Alphaproteobacteria,3JT9S@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Ion transport protein - - - ko:K10716 - - - - ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 - - Ion_trans,cNMP_binding CMS1_k127_1223314_16 288000.BBta_7154 7.244e-05 48.0 COG3210@1|root,COG4254@1|root,COG3210@2|Bacteria,COG4254@2|Bacteria,1QUXB@1224|Proteobacteria,2TWQT@28211|Alphaproteobacteria,3K6MB@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria U FecR protein - - - - - - - - - - - - FecR,Hyphal_reg_CWP CMS1_k127_1231035_3 323097.Nham_3171 1.172e-37 143.0 COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,2TQP2@28211|Alphaproteobacteria,3JUYZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Belongs to the pseudouridine synthase RsuA family rluB - 5.4.99.22 ko:K06178 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 CMS1_k127_1231035_2 1429916.X566_13340 5.529e-68 233.0 COG0590@1|root,COG0590@2|Bacteria,1RGU0@1224|Proteobacteria,2U77Q@28211|Alphaproteobacteria,3JY4W@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) tadA - 3.5.4.1,3.5.4.3,3.5.4.33 ko:K01485,ko:K01487,ko:K11991 ko00230,ko00240,ko00330,ko01100,map00230,map00240,map00330,map01100 - R00974,R01411,R01676,R02922,R10223 RC00074,RC00204,RC00477,RC00514,RC00809 ko00000,ko00001,ko01000,ko03016 - - - MafB19-deam,dCMP_cyt_deam_1 CMS1_k127_1231035_0 883078.HMPREF9695_00581 2.671e-136 437.0 COG0426@1|root,COG0426@2|Bacteria,1MXIE@1224|Proteobacteria,2U3GM@28211|Alphaproteobacteria,3JTJ2@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C domain, Protein - - - - - - - - - - - - Lactamase_B CMS1_k127_1231035_1 420324.KI912064_gene6646 5.648e-76 259.0 COG1309@1|root,COG1309@2|Bacteria,1RBV0@1224|Proteobacteria,2U7VY@28211|Alphaproteobacteria 28211|Alphaproteobacteria K COG1309 Transcriptional regulator - - - - - - - - - - - - TetR_N CMS1_k127_1231035_4 1168059.KB899087_gene3448 2.045e-11 64.0 COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,2TVQR@28211|Alphaproteobacteria,3EZZS@335928|Xanthobacteraceae 28211|Alphaproteobacteria S Patatin-like phospholipase - - - ko:K07001 - - - - ko00000 - - - Patatin CMS1_k127_1234834_1 266779.Meso_1150 9.944e-90 305.0 COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,2TRSZ@28211|Alphaproteobacteria,43IJ1@69277|Phyllobacteriaceae 28211|Alphaproteobacteria L DNA ligase - - 6.5.1.1 ko:K01971 ko03450,map03450 - R00381 RC00005 ko00000,ko00001,ko01000,ko03400 - - - DNA_ligase_A_C,DNA_ligase_A_M,LigD_N CMS1_k127_1234834_4 1380394.JADL01000001_gene2144 4.004e-25 108.0 2CA9Y@1|root,2ZXAA@2|Bacteria,1P4FN@1224|Proteobacteria,2UY3R@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_1234834_0 1230476.C207_01049 1.162e-110 363.0 COG0778@1|root,COG0778@2|Bacteria,1Q7UM@1224|Proteobacteria,2VDZM@28211|Alphaproteobacteria,3JX3R@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Nitroreductase family - - - - - - - - - - - - Nitroreductase CMS1_k127_1234834_2 1178482.BJB45_14430 1.776e-50 186.0 COG2128@1|root,COG2128@2|Bacteria,1NFKC@1224|Proteobacteria,1S22D@1236|Gammaproteobacteria 1236|Gammaproteobacteria S decarboxylase pcaC - 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 - R03470 RC00938 ko00000,ko00001,ko01000 - - - CMD CMS1_k127_1234834_3 504832.OCAR_5946 6.108e-46 170.0 COG2847@1|root,COG2847@2|Bacteria,1MZ3M@1224|Proteobacteria,2UBUR@28211|Alphaproteobacteria,3JX1P@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Copper chaperone PCu(A)C - - - ko:K09796 - - - - ko00000,ko03110 - - - PCuAC CMS1_k127_1236724_4 113395.AXAI01000001_gene3288 6.544e-86 287.0 COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,2U70Y@28211|Alphaproteobacteria,3JR5U@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L Conserved hypothetical protein 95 rsmD - 2.1.1.171 ko:K08316 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - Cons_hypoth95 CMS1_k127_1236724_0 1187851.A33M_3639 4.864e-278 867.0 COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,2TR2M@28211|Alphaproteobacteria,3FCRG@34008|Rhodovulum 28211|Alphaproteobacteria L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex mutL GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03572 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - DNA_mis_repair,HATPase_c_3,MutL_C CMS1_k127_1236724_5 1187851.A33M_3638 5.247e-51 184.0 COG1186@1|root,COG1186@2|Bacteria,1RH75@1224|Proteobacteria,2U9M7@28211|Alphaproteobacteria,3FD9Y@34008|Rhodovulum 28211|Alphaproteobacteria J RF-1 domain MA20_05665 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - ko:K15034 - - - - ko00000,ko03012 - - - RF-1 CMS1_k127_1236724_2 1429916.X566_13365 1.299e-173 555.0 COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,2TQKP@28211|Alphaproteobacteria,3JR2T@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway tal - 2.2.1.2,5.3.1.9 ko:K01810,ko:K13810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00004,M00007,M00114 R01827,R02739,R02740,R03321 RC00376,RC00439,RC00563,RC00604 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGI,TAL_FSA CMS1_k127_1236724_3 398525.KB900701_gene2723 4.989e-157 510.0 COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,2TRMX@28211|Alphaproteobacteria,3JSBY@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Peptidase M16 inactive domain pqqG - - ko:K07263,ko:K07623 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C CMS1_k127_1236724_1 1187851.A33M_0944 6.835e-180 574.0 COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2TRFB@28211|Alphaproteobacteria,3FCYB@34008|Rhodovulum 28211|Alphaproteobacteria O Peptidase M16 inactive domain MA20_05655 - - ko:K07263 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M16,Peptidase_M16_C CMS1_k127_1236724_8 1187851.A33M_0945 4.525e-31 132.0 2AXUQ@1|root,31PVX@2|Bacteria,1R6KT@1224|Proteobacteria,2UGTF@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_1236724_6 323097.Nham_3163 1.235e-49 180.0 COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,2UBUC@28211|Alphaproteobacteria,3JT06@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins lspA - 3.4.23.36 ko:K03101 ko03060,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_A8 CMS1_k127_1237271_7 1040989.AWZU01000022_gene4793 2.093e-125 404.0 COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,2TRFZ@28211|Alphaproteobacteria,3JRGR@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Transcriptional regulatory protein, C terminal phoB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K07657 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C CMS1_k127_1237271_8 1187851.A33M_3701 1.358e-106 350.0 COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,2TQMN@28211|Alphaproteobacteria,3FD4T@34008|Rhodovulum 28211|Alphaproteobacteria P Plays a role in the regulation of phosphate uptake phoU GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - ko:K02039 - - - - ko00000 - - - PhoU CMS1_k127_1237271_5 316055.RPE_4888 5.53e-131 430.0 COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,2TQX9@28211|Alphaproteobacteria,3JTBM@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran CMS1_k127_1237271_6 395964.KE386496_gene1908 2.796e-130 421.0 COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,2TQYQ@28211|Alphaproteobacteria,3NAJM@45404|Beijerinckiaceae 28211|Alphaproteobacteria P Binding-protein-dependent transport system inner membrane component pstA GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0010921,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0019220,GO:0019222,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0031323,GO:0033554,GO:0034220,GO:0035303,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051174,GO:0051179,GO:0051234,GO:0051336,GO:0051716,GO:0055085,GO:0065007,GO:0065009,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 CMS1_k127_1237271_2 1187851.A33M_3704 5.414e-156 498.0 COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,2TQU1@28211|Alphaproteobacteria,3FDA6@34008|Rhodovulum 28211|Alphaproteobacteria U probably responsible for the translocation of the substrate across the membrane pstC - - ko:K02037 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 CMS1_k127_1237271_1 1205680.CAKO01000040_gene845 1.176e-163 524.0 COG0226@1|root,COG0226@2|Bacteria,1MUAZ@1224|Proteobacteria,2TTJA@28211|Alphaproteobacteria,2JV0W@204441|Rhodospirillales 204441|Rhodospirillales P Part of the ABC transporter complex PstSACB involved in phosphate import - - - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like_2 CMS1_k127_1237271_4 288000.BBta_0757 7.306e-133 435.0 COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,2TR46@28211|Alphaproteobacteria,3JSP1@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T His Kinase A (phosphoacceptor) domain phoR - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS_4,PAS_8 CMS1_k127_1237271_3 1380355.JNIJ01000010_gene1612 5.339e-136 443.0 COG0392@1|root,COG0392@2|Bacteria,1MXH9@1224|Proteobacteria,2TUMC@28211|Alphaproteobacteria,3JTNM@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Lysylphosphatidylglycerol synthase TM region MA20_22425 - 2.3.2.3 ko:K07027,ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00726 - - ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 2.A.1.3.37,4.D.2 - - DUF2156,LPG_synthase_TM CMS1_k127_1237271_14 652103.Rpdx1_3940 1.44e-11 67.0 2ADBI@1|root,301ZK@2|Bacteria,1NAH9@1224|Proteobacteria,2UIXA@28211|Alphaproteobacteria,3K1FI@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_1237271_9 1038862.KB893895_gene6999 2.62e-87 294.0 COG1595@1|root,COG1595@2|Bacteria,1MVPD@1224|Proteobacteria,2TVKC@28211|Alphaproteobacteria,3JTB7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K Belongs to the sigma-70 factor family. ECF subfamily MA20_15865 - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4,Sigma70_r4_2 CMS1_k127_1237271_11 1126627.BAWE01000004_gene3178 3.229e-56 207.0 COG5662@1|root,COG5662@2|Bacteria,1QPSZ@1224|Proteobacteria,2TU7W@28211|Alphaproteobacteria,3JSW8@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K AntiSigma factor - - - - - - - - - - - - - CMS1_k127_1237271_13 288000.BBta_4769 9.738e-18 87.0 COG2010@1|root,COG2010@2|Bacteria,1N2SP@1224|Proteobacteria,2UEVE@28211|Alphaproteobacteria,3K0D9@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Cytochrome c - - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 CMS1_k127_1237271_10 1411123.JQNH01000001_gene2362 1.227e-67 236.0 COG0664@1|root,COG0664@2|Bacteria,1Q93V@1224|Proteobacteria,2TTEY@28211|Alphaproteobacteria 28211|Alphaproteobacteria T cyclic nucleotide-binding MA20_09210 - - - - - - - - - - - Imp-YgjV,cNMP_binding CMS1_k127_1237271_15 1267005.KB911255_gene2387 7.529e-07 52.0 COG1961@1|root,COG1961@2|Bacteria,1PWCY@1224|Proteobacteria,2TVME@28211|Alphaproteobacteria 28211|Alphaproteobacteria L COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - - - - - - - - - - Recombinase,Resolvase,Zn_ribbon_recom CMS1_k127_1237271_0 1532558.JL39_17070 5.225e-215 694.0 COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TQMW@28211|Alphaproteobacteria,4B7Q0@82115|Rhizobiaceae 28211|Alphaproteobacteria C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - 1.2.5.3 ko:K03520 - - R11168 RC02800 ko00000,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 CMS1_k127_1237271_12 1120983.KB894573_gene121 1.05e-44 168.0 COG2188@1|root,COG2188@2|Bacteria,1MVPT@1224|Proteobacteria,2U13F@28211|Alphaproteobacteria 28211|Alphaproteobacteria K UTRA domain - - - ko:K03710 - - - - ko00000,ko03000 - - - GntR,UTRA CMS1_k127_1240296_1 627192.SLG_31510 3.874e-36 139.0 COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,2TS9E@28211|Alphaproteobacteria,2K0N3@204457|Sphingomonadales 204457|Sphingomonadales J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS - 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 CMS1_k127_1240296_0 1123270.ATUR01000003_gene1121 2.242e-100 329.0 COG0433@1|root,COG0433@2|Bacteria,1MUSH@1224|Proteobacteria,2TUN9@28211|Alphaproteobacteria,2K091@204457|Sphingomonadales 204457|Sphingomonadales S Domain of unknown function DUF87 - - - ko:K06915 - - - - ko00000 - - - DUF853,DUF87 CMS1_k127_1242505_1 1218084.BBJK01000007_gene913 1.077e-62 218.0 COG2080@1|root,COG2080@2|Bacteria,1PI3V@1224|Proteobacteria,2W6PI@28216|Betaproteobacteria,1KC83@119060|Burkholderiaceae 28216|Betaproteobacteria C [2Fe-2S] binding domain - - - - - - - - - - - - Fer2,Fer2_2 CMS1_k127_1242505_0 948106.AWZT01000001_gene5084 1.889e-297 925.0 COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2VIR8@28216|Betaproteobacteria,1K1D1@119060|Burkholderiaceae 28216|Betaproteobacteria C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - - - - - - - - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 CMS1_k127_1243844_5 1298867.AUES01000017_gene3993 1.891e-10 61.0 COG0662@1|root,COG0662@2|Bacteria,1N1XN@1224|Proteobacteria,2U6GE@28211|Alphaproteobacteria,3JY7Y@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G Cupin - - - - - - - - - - - - Cupin_2 CMS1_k127_1243844_0 1100720.ALKN01000028_gene2446 4.797e-193 627.0 COG1053@1|root,COG1053@2|Bacteria,1R0GR@1224|Proteobacteria,2WHU3@28216|Betaproteobacteria 28216|Betaproteobacteria C FAD dependent oxidoreductase - - - - - - - - - - - - FAD_binding_2 CMS1_k127_1243844_3 189753.AXAS01000058_gene150 2.507e-118 387.0 COG1414@1|root,COG1414@2|Bacteria,1MUNW@1224|Proteobacteria,2TSY8@28211|Alphaproteobacteria,3JTIU@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K helix_turn_helix isocitrate lyase regulation - - - - - - - - - - - - HTH_IclR,IclR CMS1_k127_1243844_1 1038860.AXAP01000017_gene2908 6.37e-183 574.0 COG0329@1|root,COG0329@2|Bacteria,1MWAH@1224|Proteobacteria,2TSXX@28211|Alphaproteobacteria,3JX92@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria EM Dihydrodipicolinate synthetase family dapAch4 - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS CMS1_k127_1243844_2 1411123.JQNH01000001_gene2684 4.937e-126 410.0 COG4336@1|root,COG4336@2|Bacteria,1MW52@1224|Proteobacteria,2TST8@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Belongs to the D-glutamate cyclase family MA20_16485 - - - - - - - - - - - DUF1445 CMS1_k127_1243844_4 1038860.AXAP01000017_gene2909 1.032e-96 318.0 COG0683@1|root,COG0683@2|Bacteria,1MUNS@1224|Proteobacteria,2TTNM@28211|Alphaproteobacteria,3K61P@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Periplasmic binding protein domain - - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 CMS1_k127_126296_2 1131813.AQVT01000001_gene344 2.271e-13 77.0 COG0438@1|root,COG0438@2|Bacteria,1MUTA@1224|Proteobacteria,2TSPN@28211|Alphaproteobacteria,1JQP4@119045|Methylobacteriaceae 28211|Alphaproteobacteria M PFAM glycosyl transferase group 1 capM - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 CMS1_k127_126296_0 189753.AXAS01000026_gene8283 1.182e-111 368.0 COG1073@1|root,COG1073@2|Bacteria,1MX88@1224|Proteobacteria,2TSRE@28211|Alphaproteobacteria,3JSR8@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Serine aminopeptidase, S33 MA20_24420 - - ko:K06889 - - - - ko00000 - - - Abhydrolase_6,Hydrolase_4 CMS1_k127_126296_1 189753.AXAS01000026_gene8286 1.15e-60 211.0 COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,2TR5E@28211|Alphaproteobacteria,3JSKT@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) queG GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 ko:K18979 - - - - ko00000,ko01000,ko03016 - - - DUF1730,Fer4_16,HEAT_2 CMS1_k127_1265034_1 172088.AUGA01000052_gene2738 2.739e-10 66.0 29CXU@1|root,2ZZVX@2|Bacteria,1N1UK@1224|Proteobacteria,2UCXX@28211|Alphaproteobacteria,3K03H@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - MA20_24680 - - - - - - - - - - - PilZ CMS1_k127_1265034_0 172088.AUGA01000025_gene433 4.324e-68 245.0 COG3437@1|root,COG3437@2|Bacteria,1QW6V@1224|Proteobacteria,2TWQE@28211|Alphaproteobacteria,3K6P4@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria KT HD domain - - - - - - - - - - - - HD,HD_5,Response_reg CMS1_k127_1275365_1 945713.IALB_0896 3.459e-17 85.0 COG0606@1|root,COG0606@2|Bacteria 2|Bacteria O chelatase, subunit chli comM - - ko:K07391 - - - - ko00000 - - - ChlI,Mg_chelatase,Mg_chelatase_C CMS1_k127_1275365_0 1267533.KB906733_gene3355 3.009e-140 477.0 COG0577@1|root,COG0577@2|Bacteria,3Y3KJ@57723|Acidobacteria 57723|Acidobacteria V FtsX-like permease family - - - - - - - - - - - - FtsX,MacB_PCD CMS1_k127_128318_0 1232683.ADIMK_0681 2.263e-128 417.0 COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,1RN6J@1236|Gammaproteobacteria,4641I@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the cysteine synthase cystathionine beta- synthase family cysK - 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 - - - Glutaredoxin,PALP CMS1_k127_128318_1 314278.NB231_03090 1.402e-99 330.0 COG0428@1|root,COG0428@2|Bacteria,1N3QA@1224|Proteobacteria,1RR8U@1236|Gammaproteobacteria,1WY6T@135613|Chromatiales 135613|Chromatiales P divalent heavy-metal cations transporter - - - ko:K07238 - - - - ko00000,ko02000 2.A.5.5 - - - CMS1_k127_128318_3 742159.HMPREF0004_5399 2.387e-38 148.0 COG3255@1|root,COG3255@2|Bacteria,1RG3A@1224|Proteobacteria,2VX1T@28216|Betaproteobacteria,3T80I@506|Alcaligenaceae 28216|Betaproteobacteria I Sterol carrier protein - - - - - - - - - - - - - CMS1_k127_128318_2 1429916.X566_14905 1.473e-58 220.0 COG0596@1|root,COG0596@2|Bacteria,1NUT9@1224|Proteobacteria,2TVMS@28211|Alphaproteobacteria,3JT3H@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1 CMS1_k127_1285273_2 1187851.A33M_0462 0.0006272 49.0 COG1451@1|root,COG1451@2|Bacteria,1MXZU@1224|Proteobacteria,2U1JG@28211|Alphaproteobacteria,3FDB6@34008|Rhodovulum 28211|Alphaproteobacteria S Protein of unknown function DUF45 MA20_23375 - - ko:K07043 - - - - ko00000 - - - DUF45 CMS1_k127_1285273_0 1125973.JNLC01000011_gene260 2.392e-210 663.0 COG4553@1|root,COG4553@2|Bacteria,1MVUH@1224|Proteobacteria,2TQXW@28211|Alphaproteobacteria,3JTT6@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I PHB de-polymerase C-terminus phaZ - 3.1.1.75 ko:K05973 ko00650,map00650 - R05118 - ko00000,ko00001,ko01000 - - - PHB_depo_C CMS1_k127_1285273_1 1187851.A33M_0466 5.735e-130 419.0 COG0842@1|root,COG0842@2|Bacteria,1MUF4@1224|Proteobacteria,2TRTS@28211|Alphaproteobacteria 28211|Alphaproteobacteria V Transport permease protein MA20_23385 - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane CMS1_k127_1285411_3 1187851.A33M_2855 7.007e-40 158.0 COG1266@1|root,COG1266@2|Bacteria,1QPQ0@1224|Proteobacteria,2TTX7@28211|Alphaproteobacteria 28211|Alphaproteobacteria S CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi CMS1_k127_1285411_0 1187851.A33M_2856 2.973e-154 492.0 COG0604@1|root,COG0604@2|Bacteria,1MWBD@1224|Proteobacteria,2TS3Z@28211|Alphaproteobacteria,3FDZA@34008|Rhodovulum 28211|Alphaproteobacteria C Zinc-binding dehydrogenase qor - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N CMS1_k127_1285411_1 1380394.JADL01000008_gene3734 4.644e-85 287.0 COG1028@1|root,COG1028@2|Bacteria,1MW9A@1224|Proteobacteria,2TRFW@28211|Alphaproteobacteria,2JSF8@204441|Rhodospirillales 204441|Rhodospirillales IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - - - - - - - - - - adh_short_C2 CMS1_k127_1285411_2 1429916.X566_20790 2.043e-68 239.0 COG1183@1|root,COG1183@2|Bacteria,1NGCJ@1224|Proteobacteria,2TS1K@28211|Alphaproteobacteria,3JTX5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP pcs GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050520,GO:0071704,GO:0090407,GO:1901576 2.7.8.24 ko:K01004 ko00564,ko01110,map00564,map01110 - R05794 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf CMS1_k127_1304189_0 1123228.AUIH01000002_gene1626 7.969e-37 154.0 COG1664@1|root,COG1664@2|Bacteria,1NBUN@1224|Proteobacteria 1224|Proteobacteria M Polymer-forming cytoskeletal - - - - - - - - - - - - - CMS1_k127_1304189_1 1123368.AUIS01000009_gene2451 1.074e-32 146.0 COG4103@1|root,COG4103@2|Bacteria,1N6YZ@1224|Proteobacteria,1SD1K@1236|Gammaproteobacteria 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - TerB CMS1_k127_1320672_2 1089551.KE386572_gene2534 1.352e-48 175.0 COG0656@1|root,COG0656@2|Bacteria,1MX6S@1224|Proteobacteria,2U0AU@28211|Alphaproteobacteria 28211|Alphaproteobacteria S PFAM aldo keto reductase - - - - - - - - - - - - Aldo_ket_red CMS1_k127_1320672_1 420324.KI911999_gene8063 1.944e-65 235.0 2CDHC@1|root,32RXT@2|Bacteria,1N2M3@1224|Proteobacteria,2U77A@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_1320672_0 1110502.TMO_0740 2.11e-94 318.0 COG0697@1|root,COG0697@2|Bacteria,1MZQM@1224|Proteobacteria,2TUPG@28211|Alphaproteobacteria,2JQS8@204441|Rhodospirillales 204441|Rhodospirillales EG EamA-like transporter family - - - - - - - - - - - - EamA CMS1_k127_1320672_3 870187.Thini_1466 1.306e-32 132.0 COG3791@1|root,COG3791@2|Bacteria,1REMP@1224|Proteobacteria,1SXS7@1236|Gammaproteobacteria,462ZE@72273|Thiotrichales 72273|Thiotrichales S Glutathione-dependent formaldehyde-activating enzyme - - - - - - - - - - - - GFA CMS1_k127_1337353_0 1502851.FG93_04307 1.05e-55 199.0 COG1566@1|root,COG1566@2|Bacteria,1NAMI@1224|Proteobacteria,2TV2P@28211|Alphaproteobacteria,3JR6U@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria V Biotin-lipoyl like - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 CMS1_k127_1337353_1 288000.BBta_7361 1.418e-34 142.0 2CKRE@1|root,34B8T@2|Bacteria,1MX6I@1224|Proteobacteria,2TSDC@28211|Alphaproteobacteria,3JUEU@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF2865) - - - - - - - - - - - - DUF2865 CMS1_k127_1362518_1 1125973.JNLC01000010_gene1417 8.775e-273 848.0 COG2936@1|root,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,2TU0R@28211|Alphaproteobacteria,3JZ96@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain - - - ko:K06978 - - - - ko00000 - - - PepX_C,Peptidase_S15 CMS1_k127_1362518_0 1211115.ALIQ01000140_gene1266 3.357e-309 957.0 COG0129@1|root,COG0129@2|Bacteria,1MV4I@1224|Proteobacteria,2TQRW@28211|Alphaproteobacteria,3NC6A@45404|Beijerinckiaceae 28211|Alphaproteobacteria EG Dehydratase family MA20_27195 - 4.2.1.82,4.2.1.9 ko:K01687,ko:K22186 ko00040,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00040,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R01209,R02429,R04441,R05070 RC00468,RC00543,RC01714 ko00000,ko00001,ko00002,ko01000 - - - ILVD_EDD CMS1_k127_1362518_5 1038858.AXBA01000024_gene4026 3.641e-100 332.0 COG1028@1|root,COG1028@2|Bacteria,1MURZ@1224|Proteobacteria,2TQJ6@28211|Alphaproteobacteria,3EYZ9@335928|Xanthobacteraceae 28211|Alphaproteobacteria IQ Enoyl-(Acyl carrier protein) reductase MA20_27190 - 1.1.1.30 ko:K00019,ko:K18335 ko00051,ko00072,ko00650,ko01100,ko01120,map00051,map00072,map00650,map01100,map01120 M00088 R01361,R10690 RC00089,RC00117 ko00000,ko00001,ko00002,ko01000 - - - adh_short_C2 CMS1_k127_1362518_3 288000.BBta_3776 2.912e-201 635.0 COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,2TT38@28211|Alphaproteobacteria,3JT1G@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S GTPase that plays an essential role in the late steps of ribosome biogenesis der - - ko:K03977 - - - - ko00000,ko03009 - - - KH_dom-like,MMR_HSR1 CMS1_k127_1362518_10 709797.CSIRO_2587 5.26e-17 89.0 2CH5S@1|root,2ZUHH@2|Bacteria,1RKQR@1224|Proteobacteria,2TSDT@28211|Alphaproteobacteria,3JTRA@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_1362518_6 1038862.KB893856_gene822 2.295e-65 230.0 COG4649@1|root,COG4649@2|Bacteria,1P2GI@1224|Proteobacteria,2UCFZ@28211|Alphaproteobacteria,3JS1T@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Tetratricopeptide repeat-like domain - - - - - - - - - - - - TPR_21 CMS1_k127_1362518_4 316058.RPB_2445 1.037e-141 455.0 COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,2TQT1@28211|Alphaproteobacteria,3JTTZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate panB - 2.1.2.11 ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R01226 RC00022,RC00200 ko00000,ko00001,ko00002,ko01000 - - - Pantoate_transf CMS1_k127_1362518_7 1197906.CAJQ02000011_gene1070 1.289e-60 226.0 COG4094@1|root,COG4094@2|Bacteria,1RDHB@1224|Proteobacteria,2TQWY@28211|Alphaproteobacteria,3JTFH@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S NnrU protein nnrU - - - - - - - - - - - NnrU CMS1_k127_1362518_2 1125973.JNLC01000016_gene2992 4.176e-270 845.0 COG4108@1|root,COG4108@2|Bacteria,1MU7X@1224|Proteobacteria,2TRP5@28211|Alphaproteobacteria,3JRKD@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP prfC - - ko:K02837 - - - - ko00000,ko03012 - - - GTP_EFTU,GTP_EFTU_D2,RF3_C CMS1_k127_1362518_9 69395.JQLZ01000001_gene2710 6.129e-32 134.0 COG2867@1|root,COG2867@2|Bacteria,1P2TF@1224|Proteobacteria,2UUFJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Polyketide cyclase / dehydrase and lipid transport - - - - - - - - - - - - Polyketide_cyc CMS1_k127_1362518_8 288000.BBta_3754 9.705e-52 185.0 COG1393@1|root,COG1393@2|Bacteria,1MZ6S@1224|Proteobacteria,2U98B@28211|Alphaproteobacteria,3JYSH@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P Belongs to the ArsC family MA20_27840 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.20.4.1 ko:K00537 - - - - ko00000,ko01000 - - - ArsC CMS1_k127_1375333_1 316055.RPE_2750 9.961e-137 440.0 COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,2TS9E@28211|Alphaproteobacteria,3JTU7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 CMS1_k127_1375333_2 1205680.CAKO01000037_gene1225 3.282e-90 314.0 COG0477@1|root,COG2814@2|Bacteria,1R7QS@1224|Proteobacteria,2TUXM@28211|Alphaproteobacteria 28211|Alphaproteobacteria EGP Major Facilitator - - - - - - - - - - - - MFS_1 CMS1_k127_1375333_4 1230476.C207_01012 6.162e-52 192.0 COG3827@1|root,COG3827@2|Bacteria,1MX61@1224|Proteobacteria,2TSG8@28211|Alphaproteobacteria,3JS94@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF2497) - - - ko:K09991 - - - - ko00000 - - - DUF2497 CMS1_k127_1375333_0 1187851.A33M_2342 9.244e-168 541.0 COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,2TR3S@28211|Alphaproteobacteria,3FD2M@34008|Rhodovulum 28211|Alphaproteobacteria MU Outer membrane efflux protein tolC - - ko:K12340 ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133 M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko02044 1.B.17,2.A.6.2 - - OEP CMS1_k127_1375333_3 1187851.A33M_2343 1.175e-55 201.0 COG2518@1|root,COG2518@2|Bacteria,1RD6S@1224|Proteobacteria,2U704@28211|Alphaproteobacteria,3FD5P@34008|Rhodovulum 28211|Alphaproteobacteria J Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) pcm2 - 2.1.1.77 ko:K00573 - - - - ko00000,ko01000 - - - PCMT CMS1_k127_1382638_3 1397528.Q671_10595 4.621e-05 50.0 COG2963@1|root,COG2963@2|Bacteria,1NGD6@1224|Proteobacteria,1SFD4@1236|Gammaproteobacteria,1XMMN@135619|Oceanospirillales 135619|Oceanospirillales L Transposase - - - - - - - - - - - - HTH_Tnp_1 CMS1_k127_1382638_1 497964.CfE428DRAFT_4733 3.313e-29 121.0 COG3436@1|root,COG3436@2|Bacteria 2|Bacteria L PFAM IS66 Orf2 family protein - - - ko:K07484 - - - - ko00000 - - - TnpB_IS66 CMS1_k127_1382638_0 497964.CfE428DRAFT_4819 1.623e-86 305.0 COG2433@1|root,COG2433@2|Bacteria,46Z8U@74201|Verrucomicrobia 2|Bacteria S PFAM transposase IS66 - - - ko:K07484 - - - - ko00000 - - - DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66 CMS1_k127_1382638_2 997346.HMPREF9374_1123 3.584e-08 60.0 COG0507@1|root,COG0507@2|Bacteria,1TQWH@1239|Firmicutes,4HF2Y@91061|Bacilli 91061|Bacilli L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD - - - - - - - - - - - - - CMS1_k127_1391158_1 1038859.AXAU01000001_gene2965 5.342e-258 802.0 COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,2TSNK@28211|Alphaproteobacteria,3JTNA@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C NADH-ubiquinone oxidoreductase chain 4, amino terminus nuoM GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 ko:K00342 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q5_N,Proton_antipo_M CMS1_k127_1391158_0 1380355.JNIJ01000025_gene1205 4.529e-320 985.0 COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,2TQSS@28211|Alphaproteobacteria,3JSBH@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria CP NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus nuoL - 1.6.5.3 ko:K00341 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - NADH5_C,Proton_antipo_M,Proton_antipo_N CMS1_k127_1400798_3 1197906.CAJQ02000051_gene70 2.748e-47 174.0 COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,2UBUP@28211|Alphaproteobacteria,3JZQH@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria D Important for reducing fluoride concentration in the cell, thus reducing its toxicity crcB - - ko:K06199 - - - - ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 - - CRCB CMS1_k127_1400798_0 1411123.JQNH01000001_gene2483 1.448e-170 541.0 COG3055@1|root,COG3055@2|Bacteria,1QSB4@1224|Proteobacteria,2U0J2@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Kelch repeat protein - - - - - - - - - - - - Kelch_1,Kelch_2,Kelch_4,Kelch_6 CMS1_k127_1400798_1 1187851.A33M_0606 1.671e-153 494.0 COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,2TSD6@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism bioB - 2.8.1.6 ko:K01012 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R01078 RC00441 ko00000,ko00001,ko00002,ko01000 - - - BATS,Radical_SAM CMS1_k127_1400798_2 1530186.JQEY01000015_gene353 5.326e-103 343.0 COG2133@1|root,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,2TRN9@28211|Alphaproteobacteria 28211|Alphaproteobacteria G glucose sorbosone - - - - - - - - - - - - GSDH,PBP CMS1_k127_1410819_0 288000.BBta_1749 0.0 1186.0 COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TQMW@28211|Alphaproteobacteria,3JUMW@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain coxL - 1.2.5.3 ko:K03520 - - R11168 RC02800 ko00000,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 CMS1_k127_1410819_1 1411123.JQNH01000001_gene1485 1.577e-85 301.0 COG0714@1|root,COG0714@2|Bacteria,1MV5I@1224|Proteobacteria,2TREB@28211|Alphaproteobacteria 28211|Alphaproteobacteria S COG0714 MoxR-like ATPases coxD - - - - - - - - - - - AAA_5 CMS1_k127_1428712_8 1094489.BAnh1_11600 5.237e-20 97.0 COG5480@1|root,COG5480@2|Bacteria,1RISQ@1224|Proteobacteria,2U9NW@28211|Alphaproteobacteria,48SXZ@772|Bartonellaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF1036) MA20_03870 - - - - - - - - - - - DUF1036 CMS1_k127_1428712_2 391937.NA2_11175 2.778e-100 332.0 COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,2TSIZ@28211|Alphaproteobacteria,43HN5@69277|Phyllobacteriaceae 28211|Alphaproteobacteria J Belongs to the RNA methyltransferase TrmD family trmD GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 ko:K00554 - - R00597 RC00003,RC00334 ko00000,ko01000,ko03016 - - - tRNA_m1G_MT CMS1_k127_1428712_4 1125973.JNLC01000013_gene4068 7.343e-60 214.0 COG0806@1|root,COG0806@2|Bacteria,1MWQR@1224|Proteobacteria,2U9UT@28211|Alphaproteobacteria,3JT77@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes rimM - - ko:K02860 - - - - ko00000,ko03009 - - - PRC,RimM CMS1_k127_1428712_6 504832.OCAR_4268 7.157e-49 178.0 COG0228@1|root,COG0228@2|Bacteria,1MZCT@1224|Proteobacteria,2U94X@28211|Alphaproteobacteria,3JYTG@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Belongs to the bacterial ribosomal protein bS16 family rpsP GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02959 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S16 CMS1_k127_1428712_0 666684.AfiDRAFT_1413 7.772e-244 763.0 COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,2TQSW@28211|Alphaproteobacteria,3JR15@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components ffh - 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 - - SRP54,SRP54_N,SRP_SPB CMS1_k127_1428712_5 1298867.AUES01000040_gene948 1.767e-52 193.0 COG2968@1|root,COG2968@2|Bacteria,1RH7T@1224|Proteobacteria,2U981@28211|Alphaproteobacteria,3JVGB@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF541) omp28 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - ko:K09807 - - - - ko00000 - - - SIMPL CMS1_k127_1428712_7 652103.Rpdx1_0385 9.904e-46 174.0 COG4978@1|root,COG4978@2|Bacteria,1R4X9@1224|Proteobacteria,2TUZK@28211|Alphaproteobacteria,3JTV1@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria KT Bacterial transcription activator, effector binding domain MA20_43725 - - - - - - - - - - - GyrI-like CMS1_k127_1428712_1 1297863.APJF01000016_gene4286 5.673e-140 450.0 COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,2TUF2@28211|Alphaproteobacteria,3JR65@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan dapF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00527 R02735 RC00302 ko00000,ko00001,ko00002,ko01000 - - - DAP_epimerase CMS1_k127_1428712_3 1207063.P24_06651 1.36e-79 269.0 COG0621@1|root,COG0621@2|Bacteria,1MUCS@1224|Proteobacteria,2TRYD@28211|Alphaproteobacteria,2JPRM@204441|Rhodospirillales 204441|Rhodospirillales J Uncharacterized protein family UPF0004 - - 2.8.4.5 ko:K18707 - - R10649 RC00003,RC03221 ko00000,ko01000,ko03016 - - - Radical_SAM,UPF0004 CMS1_k127_1428907_5 258594.RPA3588 2.272e-56 198.0 COG0654@1|root,COG0654@2|Bacteria,1MXEW@1224|Proteobacteria,2TRRC@28211|Alphaproteobacteria,3JV1F@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria CH Function proposed based on presence of conserved amino acid motif, structural feature or limited homology MA20_42420 - 1.14.13.218 ko:K20940 ko00405,ko01130,map00405,map01130 M00835 - - ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 CMS1_k127_1428907_7 1429916.X566_19140 1.091e-28 121.0 2EH5K@1|root,33AXH@2|Bacteria,1RJRX@1224|Proteobacteria,2UB40@28211|Alphaproteobacteria,3JZR3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_1428907_4 323098.Nwi_2117 2.57e-58 209.0 COG0071@1|root,COG0071@2|Bacteria,1RH2X@1224|Proteobacteria,2U6S6@28211|Alphaproteobacteria,3JY2U@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O Hsp20/alpha crystallin family - - - ko:K04080 - - - - ko00000,ko03110 - - - HSP20 CMS1_k127_1428907_0 460265.Mnod_0848 2.21e-177 561.0 COG0604@1|root,COG0604@2|Bacteria,1R8NX@1224|Proteobacteria,2TUG0@28211|Alphaproteobacteria,1JYZZ@119045|Methylobacteriaceae 28211|Alphaproteobacteria C PFAM Alcohol dehydrogenase zinc-binding domain protein - - - - - - - - - - - - ADH_N,ADH_zinc_N_2 CMS1_k127_1428907_1 1532558.JL39_30970 1.322e-104 342.0 COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,1PH90@1224|Proteobacteria,2V8I7@28211|Alphaproteobacteria,4BE6C@82115|Rhizobiaceae 28211|Alphaproteobacteria K AraC-like ligand binding domain - - - - - - - - - - - - Cupin_2,HTH_3 CMS1_k127_1428907_2 224911.27353466 6.207e-77 262.0 COG2335@1|root,COG2335@2|Bacteria,1RD06@1224|Proteobacteria,2U7H5@28211|Alphaproteobacteria,3JYDJ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - - - - - - - - - - Fasciclin CMS1_k127_1428907_3 1038867.AXAY01000028_gene4730 1.424e-62 226.0 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TR8X@28211|Alphaproteobacteria 28211|Alphaproteobacteria T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,PAS,PAS_3,Response_reg CMS1_k127_1428907_6 1197906.CAJQ02000043_gene2051 2.114e-48 177.0 COG0302@1|root,COG0302@2|Bacteria,1MY3N@1224|Proteobacteria,2TSZI@28211|Alphaproteobacteria,3JSQ7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H GTP cyclohydrolase folE - 3.5.4.16 ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 - - - GTP_cyclohydroI CMS1_k127_1432578_0 700508.D174_16915 9.178e-126 414.0 COG4638@1|root,COG4638@2|Bacteria,2GP4B@201174|Actinobacteria,23306@1762|Mycobacteriaceae 201174|Actinobacteria P PFAM ring hydroxylating dioxygenase, alpha subunit - - 1.14.12.10,1.14.12.25 ko:K05549,ko:K10619 ko00362,ko00364,ko00622,ko01100,ko01120,ko01220,map00362,map00364,map00622,map01100,map01120,map01220 M00539,M00551 R05247,R05290,R05291,R05428,R05621,R05622,R05665,R08100,R08101,R08108,R08109,R08110 RC00267,RC00270,RC01378,RC01450,RC01910 br01602,ko00000,ko00001,ko00002,ko01000 - - - Rieske,Ring_hydroxyl_A CMS1_k127_1432578_2 1231391.AMZF01000041_gene723 3.825e-30 130.0 COG1309@1|root,COG1309@2|Bacteria,1N7FT@1224|Proteobacteria 1224|Proteobacteria K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_C_9,TetR_N CMS1_k127_1432578_1 1068978.AMETH_1184 6.445e-38 155.0 COG1028@1|root,COG1028@2|Bacteria,2IDH2@201174|Actinobacteria 201174|Actinobacteria IQ Enoyl-(Acyl carrier protein) reductase - - 1.3.1.58 ko:K10620 ko00622,ko01120,ko01220,map00622,map01120,map01220 M00539 R05240 RC00057 br01602,ko00000,ko00001,ko00002,ko01000 - - - adh_short_C2 CMS1_k127_1450311_2 935261.JAGL01000024_gene24 6.879e-36 136.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TR15@28211|Alphaproteobacteria,43I97@69277|Phyllobacteriaceae 28211|Alphaproteobacteria I acyl-CoA dehydrogenase ACADL - 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N CMS1_k127_1450311_0 1411123.JQNH01000001_gene3622 1.254e-214 673.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2TS1R@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Belongs to the thiolase family fadA GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006725,GO:0006805,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016020,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019439,GO:0019748,GO:0019752,GO:0030258,GO:0030312,GO:0032787,GO:0033554,GO:0033812,GO:0034440,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0071944,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N CMS1_k127_1450311_1 1187851.A33M_2218 8.395e-66 228.0 COG3837@1|root,COG3837@2|Bacteria,1R9WZ@1224|Proteobacteria,2VARS@28211|Alphaproteobacteria,3FEBA@34008|Rhodovulum 28211|Alphaproteobacteria S Protein of unknown function (DUF861) - - - - - - - - - - - - Cupin_2 CMS1_k127_1450311_3 316058.RPB_4604 1.704e-31 125.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2TS8E@28211|Alphaproteobacteria,3JSUZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I enoyl-CoA hydratase isomerase fadJ - 1.1.1.35,4.2.1.17,5.1.2.3 ko:K01782 ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212 M00032,M00087 R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094 RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - - 3HCDH,3HCDH_N,ECH_1 CMS1_k127_1452543_10 631454.N177_3544 4.913e-45 163.0 COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,2TS63@28211|Alphaproteobacteria,1JN3Z@119043|Rhodobiaceae 28211|Alphaproteobacteria C Citrate synthase, C-terminal domain gltA - 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt CMS1_k127_1452543_9 998674.ATTE01000001_gene3829 1.035e-62 220.0 COG3193@1|root,COG3193@2|Bacteria,1N08N@1224|Proteobacteria,1S8SV@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Glcg protein glcG - - - - - - - - - - - Haem_degrading CMS1_k127_1452543_2 1166018.FAES_0948 7.395e-156 498.0 COG0332@1|root,COG0332@2|Bacteria,4NEYH@976|Bacteroidetes,47KV4@768503|Cytophagia 976|Bacteroidetes I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids fabH GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0071704 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C CMS1_k127_1452543_3 323098.Nwi_1846 1.114e-136 445.0 COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,2TSEA@28211|Alphaproteobacteria,3JUMR@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxB GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 ko:K00748 ko00540,ko01100,map00540,map01100 M00060 R04606 RC00005,RC00059 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT19 - LpxB CMS1_k127_1452543_7 1187851.A33M_2122 9.842e-97 324.0 COG3494@1|root,COG3494@2|Bacteria,1MWTH@1224|Proteobacteria,2U4AB@28211|Alphaproteobacteria,3FD74@34008|Rhodovulum 28211|Alphaproteobacteria S Protein of unknown function (DUF1009) cdsA2 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - ko:K09949 - - - - ko00000 - - - DUF1009 CMS1_k127_1452543_6 1187851.A33M_2121 2.425e-103 347.0 COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,2TRK9@28211|Alphaproteobacteria,3FD23@34008|Rhodovulum 28211|Alphaproteobacteria M Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxA - 2.3.1.129 ko:K00677 ko00540,ko01100,ko01503,map00540,map01100,map01503 M00060 R04567 RC00039,RC00055 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Acetyltransf_11,Hexapep CMS1_k127_1452543_8 1411123.JQNH01000001_gene1432 2.932e-63 221.0 COG0764@1|root,COG0764@2|Bacteria,1RH2T@1224|Proteobacteria,2U7G4@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs fabZ - 4.2.1.59 ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121 RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FabA CMS1_k127_1452543_4 1187851.A33M_2119 1.892e-124 413.0 COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,2TS8U@28211|Alphaproteobacteria,3FD96@34008|Rhodovulum 28211|Alphaproteobacteria I Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxD - 2.3.1.191 ko:K02536 ko00540,ko01100,map00540,map01100 M00060 R04550 RC00039,RC00166 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Hexapep,Hexapep_2,LpxD CMS1_k127_1452543_0 1187851.A33M_2118 1.274e-318 993.0 COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,2TR7W@28211|Alphaproteobacteria,3FCTT@34008|Rhodovulum 28211|Alphaproteobacteria M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane bamA - - ko:K07277 - - - - ko00000,ko02000,ko03029 1.B.33 - - Bac_surface_Ag,POTRA CMS1_k127_1452543_1 1429916.X566_21490 1.821e-168 537.0 COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,2TQXJ@28211|Alphaproteobacteria,3JSGZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M zinc metalloprotease rseP - - ko:K11749 ko02024,ko04112,map02024,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ_2,Peptidase_M50 CMS1_k127_1452543_5 1187851.A33M_2116 1.366e-113 370.0 COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,2TSD1@28211|Alphaproteobacteria,3FCQK@34008|Rhodovulum 28211|Alphaproteobacteria I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) dxr GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05688 RC01452 ko00000,ko00001,ko00002,ko01000 - - - DXPR_C,DXP_redisom_C,DXP_reductoisom CMS1_k127_1474208_6 1429916.X566_24130 8.765e-45 169.0 COG2343@1|root,COG2343@2|Bacteria,1RHXD@1224|Proteobacteria,2UC5N@28211|Alphaproteobacteria,3JYPZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Domain of unknown function (DUF427) MA20_09120 - - - - - - - - - - - NTP_transf_9 CMS1_k127_1474208_0 1380355.JNIJ01000039_gene5391 3.575e-160 509.0 COG0265@1|root,COG0265@2|Bacteria,1MURF@1224|Proteobacteria,2TUVW@28211|Alphaproteobacteria,3JT2K@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O Domain present in PSD-95, Dlg, and ZO-1/2. MA20_20705 - - - - - - - - - - - PDZ_2,Trypsin_2 CMS1_k127_1474208_1 1230476.C207_03063 8.385e-136 439.0 COG2141@1|root,COG2141@2|Bacteria,1MVF0@1224|Proteobacteria,2TTR7@28211|Alphaproteobacteria,3JV9M@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Luciferase-like monooxygenase MA20_18520 - - - - - - - - - - - Bac_luciferase CMS1_k127_1474208_3 335659.S23_69470 8.476e-88 296.0 COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,2TTPH@28211|Alphaproteobacteria,3JRDU@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria Q Dienelactone hydrolase family MA20_23640 - 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 - R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 - - - DLH CMS1_k127_1474208_5 258594.RPA4833 3.067e-58 214.0 COG1596@1|root,COG1596@2|Bacteria,1MXYS@1224|Proteobacteria,2U93S@28211|Alphaproteobacteria,3JTS2@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Polysaccharide biosynthesis/export protein gumB - - ko:K01991 ko02026,map02026 - - - ko00000,ko00001,ko02000 1.B.18 - - Poly_export,SLBB CMS1_k127_1474208_2 402881.Plav_2156 1.473e-111 364.0 COG0225@1|root,COG0225@2|Bacteria,1MVUS@1224|Proteobacteria,2TSAM@28211|Alphaproteobacteria,1JN6P@119043|Rhodobiaceae 28211|Alphaproteobacteria O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine msrA - 1.8.4.11 ko:K07304 - - - - ko00000,ko01000 - - - PMSR CMS1_k127_1474208_7 1187851.A33M_2517 3.801e-26 111.0 2EH7Y@1|root,33AZT@2|Bacteria,1RHZF@1224|Proteobacteria,2U9CY@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - MA20_23660 - - - - - - - - - - - - CMS1_k127_1474208_4 426117.M446_6546 1.151e-67 233.0 COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,2TQJT@28211|Alphaproteobacteria,1JQS0@119045|Methylobacteriaceae 28211|Alphaproteobacteria C Phosphate acetyl butaryl transferase tme - 1.1.1.40 ko:K00029 ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200 M00169,M00172 R00216 RC00105 ko00000,ko00001,ko00002,ko01000 - - - Malic_M,PTA_PTB,malic CMS1_k127_1475315_4 570967.JMLV01000005_gene57 0.0009972 45.0 COG4325@1|root,COG4325@2|Bacteria,1MXTM@1224|Proteobacteria,2TRWI@28211|Alphaproteobacteria,2JSM4@204441|Rhodospirillales 204441|Rhodospirillales S Predicted membrane protein (DUF2254) - - - - - - - - - - - - DUF2254 CMS1_k127_1475315_0 1510531.JQJJ01000009_gene860 3.739e-129 419.0 COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,2TRHR@28211|Alphaproteobacteria,3JSBB@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Belongs to the pirin family MA20_23765 - - ko:K06911 - - - - ko00000 - - - Pirin,Pirin_C CMS1_k127_1475315_2 1041139.KB902724_gene4151 6.529e-86 294.0 COG0625@1|root,COG0625@2|Bacteria,1RK1K@1224|Proteobacteria,2V5U1@28211|Alphaproteobacteria,4BGB5@82115|Rhizobiaceae 28211|Alphaproteobacteria O Glutathione S-transferase, C-terminal domain - - - - - - - - - - - - GST_C,GST_N CMS1_k127_1475315_1 1120792.JAFV01000001_gene970 2.897e-97 338.0 COG4943@1|root,COG4943@2|Bacteria,1MVTH@1224|Proteobacteria,2TTKR@28211|Alphaproteobacteria,36ZA1@31993|Methylocystaceae 28211|Alphaproteobacteria T Putative diguanylate phosphodiesterase - - - - - - - - - - - - CSS-motif,EAL CMS1_k127_1475315_3 1187851.A33M_3309 1.787e-19 92.0 2CFWH@1|root,2ZXU9@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Gly-zipper_Omp,Gly-zipper_YMGG CMS1_k127_148314_5 1187851.A33M_1992 2.192e-87 297.0 COG3745@1|root,COG3745@2|Bacteria,1MW75@1224|Proteobacteria,2TTPE@28211|Alphaproteobacteria,3FDAN@34008|Rhodovulum 28211|Alphaproteobacteria U SAF cpaB - - ko:K02279 - - - - ko00000,ko02035,ko02044 - - - RcpC,SAF CMS1_k127_148314_1 1187851.A33M_1993 9.026e-170 549.0 COG4964@1|root,COG4964@2|Bacteria,1MV8G@1224|Proteobacteria,2TRNN@28211|Alphaproteobacteria,3FCWR@34008|Rhodovulum 28211|Alphaproteobacteria U Pilus formation protein N terminal region cpaC - - ko:K02280 - - - - ko00000,ko02035,ko02044 - - - BON,Secretin,T2SS-T3SS_pil_N CMS1_k127_148314_10 460265.Mnod_3785 3.45e-20 94.0 2EIGZ@1|root,33C8B@2|Bacteria,1PNJ7@1224|Proteobacteria,2UMFX@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_148314_2 1187851.A33M_1995 2.936e-164 526.0 COG4963@1|root,COG4963@2|Bacteria,1MWNY@1224|Proteobacteria,2TUDS@28211|Alphaproteobacteria,3FDF1@34008|Rhodovulum 28211|Alphaproteobacteria U AAA domain minD - - ko:K02282 - - - - ko00000,ko02035,ko02044 - - - AAA_31 CMS1_k127_148314_0 1187851.A33M_1996 1.108e-231 725.0 COG4962@1|root,COG4962@2|Bacteria,1R7EN@1224|Proteobacteria,2TRNT@28211|Alphaproteobacteria,3FCFW@34008|Rhodovulum 28211|Alphaproteobacteria U Type II/IV secretion system protein cpaF - - ko:K02283 - - - - ko00000,ko02035,ko02044 - - - T2SSE CMS1_k127_148314_3 1187851.A33M_1997 6.576e-112 385.0 COG4965@1|root,COG4965@2|Bacteria,1MUXK@1224|Proteobacteria,2TRBI@28211|Alphaproteobacteria,3FD3Q@34008|Rhodovulum 28211|Alphaproteobacteria U Type II secretion system (T2SS), protein F - - - ko:K12510 - - - - ko00000,ko02044 - - - T2SSF CMS1_k127_148314_4 1187851.A33M_1998 1.115e-109 363.0 COG2064@1|root,COG2064@2|Bacteria,1MWAZ@1224|Proteobacteria,2TSFA@28211|Alphaproteobacteria,3FD8W@34008|Rhodovulum 28211|Alphaproteobacteria NU Type II secretion system (T2SS), protein F - - - ko:K12511 - - - - ko00000,ko02044 - - - T2SSF CMS1_k127_148314_7 1187851.A33M_1991 7.14e-39 155.0 COG3063@1|root,COG3063@2|Bacteria,1R6IJ@1224|Proteobacteria,2TTCB@28211|Alphaproteobacteria 28211|Alphaproteobacteria NU Tetratricopeptide TPR_2 repeat protein - - - - - - - - - - - - TPR_16,TPR_2,TPR_8 CMS1_k127_148314_8 1298867.AUES01000057_gene4849 4.18e-29 121.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind CMS1_k127_148314_6 1297863.APJF01000008_gene764 6.731e-44 166.0 2DMYT@1|root,32UF9@2|Bacteria,1REV0@1224|Proteobacteria,2U8Z0@28211|Alphaproteobacteria,3K0D4@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S SPW repeat - - - - - - - - - - - - SPW CMS1_k127_148314_9 1040989.AWZU01000065_gene6522 2.229e-26 108.0 COG0745@1|root,COG2203@1|root,COG0745@2|Bacteria,COG2203@2|Bacteria,1RBCR@1224|Proteobacteria,2U9JF@28211|Alphaproteobacteria,3JYAE@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria KT cheY-homologous receiver domain MA20_16795 - - - - - - - - - - - Response_reg CMS1_k127_1490372_1 1123393.KB891330_gene878 4.08e-11 63.0 COG1881@1|root,COG1881@2|Bacteria,1N0Y4@1224|Proteobacteria,2VR39@28216|Betaproteobacteria 28216|Betaproteobacteria S PFAM PEBP family protein - - - ko:K06910 - - - - ko00000 - - - PBP CMS1_k127_1490372_0 1095769.CAHF01000011_gene2303 2.792e-192 618.0 COG1368@1|root,COG1368@2|Bacteria,1MVCM@1224|Proteobacteria,2VMSK@28216|Betaproteobacteria,4759H@75682|Oxalobacteraceae 28216|Betaproteobacteria M Sulfatase - - - - - - - - - - - - Sulfatase CMS1_k127_1511612_4 1038859.AXAU01000019_gene4794 1.425e-103 345.0 COG0560@1|root,COG0560@2|Bacteria,1MWA3@1224|Proteobacteria,2TSEU@28211|Alphaproteobacteria,3JSAV@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E phosphoserine phosphatase serB - 3.1.3.3 ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R00582 RC00017 ko00000,ko00001,ko00002,ko01000,ko01009 - - - HAD CMS1_k127_1511612_0 1187851.A33M_3363 4.847e-212 669.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2TQPZ@28211|Alphaproteobacteria,3FCKC@34008|Rhodovulum 28211|Alphaproteobacteria O Trypsin degP GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ,PDZ_2,Trypsin_2 CMS1_k127_1511612_12 1231190.NA8A_04988 1.066e-15 78.0 COG3242@1|root,COG3242@2|Bacteria,1NGPZ@1224|Proteobacteria,2UJA9@28211|Alphaproteobacteria,43M7X@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S protein conserved in bacteria MA20_02305 - - ko:K09937 - - - - ko00000 - - - DUF2065 CMS1_k127_1511612_3 1187851.A33M_3361 1.704e-129 421.0 COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,2TRP4@28211|Alphaproteobacteria,3FD2U@34008|Rhodovulum 28211|Alphaproteobacteria O HflC and HflK could regulate a protease hflC - - ko:K04087 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7 CMS1_k127_1511612_1 1298867.AUES01000006_gene408 9.63e-173 550.0 COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,2TRTP@28211|Alphaproteobacteria,3JVAF@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O HflC and HflK could encode or regulate a protease hflK - - ko:K04088 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7,HflK_N CMS1_k127_1511612_7 652103.Rpdx1_1866 3.898e-53 192.0 COG0262@1|root,COG0262@2|Bacteria,1RH0P@1224|Proteobacteria,2U9GC@28211|Alphaproteobacteria,3JQWH@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis folA - 1.5.1.3 ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 ko00000,ko00001,ko00002,ko01000 - - - DHFR_1 CMS1_k127_1511612_5 172088.AUGA01000004_gene3875 8.353e-66 229.0 COG0454@1|root,COG0454@2|Bacteria,1QTZ4@1224|Proteobacteria,2U7E4@28211|Alphaproteobacteria,3JV2E@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K FR47-like protein MA20_02285 - 2.3.1.57 ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 M00135 R01154 RC00004,RC00096 ko00000,ko00001,ko00002,ko01000 - - - Acetyltransf_1 CMS1_k127_1511612_2 883078.HMPREF9695_02969 6.153e-151 489.0 COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,2TQSB@28211|Alphaproteobacteria,3JV7Q@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA - 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt CMS1_k127_1511612_10 1287116.X734_08590 2.273e-37 147.0 2DRYZ@1|root,33DRE@2|Bacteria,1NWP2@1224|Proteobacteria,2USAQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_1511612_6 196490.AUEZ01000002_gene4292 9.469e-62 219.0 COG2059@1|root,COG2059@2|Bacteria,1RAZW@1224|Proteobacteria,2U4CM@28211|Alphaproteobacteria,3JTFF@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P Chromate transporter MA20_02260 - - ko:K07240 - - - - ko00000,ko02000 2.A.51.1 - - Chromate_transp CMS1_k127_1511612_8 652103.Rpdx1_1859 1.786e-47 177.0 COG2059@1|root,COG2059@2|Bacteria,1MZHQ@1224|Proteobacteria,2U0QZ@28211|Alphaproteobacteria,3JRKM@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P Chromate transporter - - - ko:K07240 - - - - ko00000,ko02000 2.A.51.1 - - Chromate_transp CMS1_k127_1511612_9 296591.Bpro_0015 2.542e-43 168.0 COG1073@1|root,COG1073@2|Bacteria,1N03B@1224|Proteobacteria,2VV1P@28216|Betaproteobacteria,4AFPY@80864|Comamonadaceae 28216|Betaproteobacteria S alpha beta - - - - - - - - - - - - Abhydrolase_6,Hydrolase_4 CMS1_k127_1511612_11 189753.AXAS01000029_gene6960 4.304e-25 114.0 2F5Y8@1|root,33YGV@2|Bacteria,1MV4P@1224|Proteobacteria,2TUJF@28211|Alphaproteobacteria,3JWNU@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - MA20_10390 - - - - - - - - - - - - CMS1_k127_157117_9 1206720.BAFQ01000111_gene2779 1.084e-50 188.0 COG2030@1|root,COG2030@2|Bacteria,2HFAT@201174|Actinobacteria,4G2BV@85025|Nocardiaceae 201174|Actinobacteria I MaoC like domain - - - - - - - - - - - - MaoC_dehydratas CMS1_k127_157117_6 1187851.A33M_1562 6.148e-124 404.0 COG1082@1|root,COG1082@2|Bacteria,1Q173@1224|Proteobacteria,2TTFM@28211|Alphaproteobacteria 28211|Alphaproteobacteria G xylose isomerase MA20_16875 - - - - - - - - - - - AP_endonuc_2 CMS1_k127_157117_3 1041138.KB890253_gene4344 2.407e-182 577.0 COG0329@1|root,COG0329@2|Bacteria,1MV7E@1224|Proteobacteria,2TTT5@28211|Alphaproteobacteria,4BAJF@82115|Rhizobiaceae 28211|Alphaproteobacteria EM Protein of unknown function (DUF993) - - - - - - - - - - - - DUF993 CMS1_k127_157117_2 311403.Arad_4620 1.075e-202 636.0 COG0673@1|root,COG0673@2|Bacteria,1PYTN@1224|Proteobacteria,2TS0G@28211|Alphaproteobacteria,4B8GX@82115|Rhizobiaceae 28211|Alphaproteobacteria S oxidoreductase MA20_16885 - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C CMS1_k127_157117_8 1500306.JQLA01000007_gene6215 8.801e-70 244.0 COG1309@1|root,COG1309@2|Bacteria,1R5AI@1224|Proteobacteria,2U7HG@28211|Alphaproteobacteria,4B7TX@82115|Rhizobiaceae 28211|Alphaproteobacteria K transcriptional regulator - - - ko:K09017 - - - - ko00000,ko03000 - - - TetR_C_3,TetR_N CMS1_k127_157117_0 1042326.AZNV01000005_gene4346 4.053e-317 978.0 COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,2TT2P@28211|Alphaproteobacteria,4B9EQ@82115|Rhizobiaceae 28211|Alphaproteobacteria C Elongator protein 3, MiaB family, Radical SAM - - - - - - - - - - - - Radical_SAM CMS1_k127_157117_10 717785.HYPMC_3315 1.625e-33 131.0 COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria 1224|Proteobacteria K Cold shock cspA - - ko:K03704 - - - - ko00000,ko03000 - - - CSD CMS1_k127_157117_12 224911.27348613 2.796e-27 118.0 COG0828@1|root,COG0828@2|Bacteria,1MZA1@1224|Proteobacteria,2UBYP@28211|Alphaproteobacteria,3K0J2@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Ribosomal protein S21 rpsU GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - ko:K02970 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S21 CMS1_k127_157117_5 1037409.BJ6T_23800 8.458e-139 446.0 COG1733@1|root,COG1733@2|Bacteria,1NEKW@1224|Proteobacteria,2U0MC@28211|Alphaproteobacteria,3JTRU@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K HxlR-like helix-turn-helix - - - - - - - - - - - - HxlR,SCP2 CMS1_k127_157117_1 1037409.BJ6T_23810 1.083e-275 852.0 COG0277@1|root,COG0277@2|Bacteria,1MUPW@1224|Proteobacteria,2TUNK@28211|Alphaproteobacteria,3JSHP@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Berberine and berberine like - - - - - - - - - - - - BBE,FAD_binding_4 CMS1_k127_157117_11 709797.CSIRO_4146 1.33e-27 113.0 COG2261@1|root,COG2261@2|Bacteria,1N72Y@1224|Proteobacteria,2UFM5@28211|Alphaproteobacteria,3K0CJ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Transglycosylase associated protein MA20_01300 - - - - - - - - - - - Transgly_assoc CMS1_k127_157117_4 316056.RPC_1940 2.137e-152 497.0 COG0668@1|root,COG0668@2|Bacteria,1MW1F@1224|Proteobacteria,2TTVC@28211|Alphaproteobacteria 28211|Alphaproteobacteria M mechanosensitive ion channel - - - - - - - - - - - - BON,MS_channel CMS1_k127_157117_7 323097.Nham_2535 4.197e-90 302.0 COG0664@1|root,COG0664@2|Bacteria,1MV7G@1224|Proteobacteria,2U1I4@28211|Alphaproteobacteria,3JUCQ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K Transcriptional regulator, Crp Fnr family - - - - - - - - - - - - HTH_Crp_2,cNMP_binding CMS1_k127_1572973_3 639283.Snov_1787 3.724e-26 111.0 COG1546@1|root,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,2U94H@28211|Alphaproteobacteria,3EZT1@335928|Xanthobacteraceae 28211|Alphaproteobacteria S Belongs to the CinA family cinA - 3.5.1.42 ko:K03743 ko00760,map00760 - R02322 RC00100 ko00000,ko00001,ko01000 - - - CinA CMS1_k127_1572973_0 1187851.A33M_2250 2.065e-163 522.0 COG0245@1|root,COG1211@1|root,COG0245@2|Bacteria,COG1211@2|Bacteria,1MVHA@1224|Proteobacteria,2TRQC@28211|Alphaproteobacteria,3FCMY@34008|Rhodovulum 28211|Alphaproteobacteria I Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) ispDF - 2.7.7.60,4.6.1.12 ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05633,R05637 RC00002,RC01440 ko00000,ko00001,ko00002,ko01000 - - - IspD,YgbB CMS1_k127_1572973_1 323097.Nham_1835 2.229e-135 439.0 COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,2TRC8@28211|Alphaproteobacteria,3JSGQ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines dusB - - ko:K05540 - - - - ko00000,ko01000,ko03016 - - - Dus CMS1_k127_1572973_2 1297863.APJF01000001_gene2222 3.904e-42 157.0 COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,2TQS1@28211|Alphaproteobacteria,3JRY2@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Signal transduction histidine kinase, nitrogen specific ntrB - 2.7.13.3 ko:K07708 ko02020,map02020 M00497 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_4 CMS1_k127_16181_1 1380391.JIAS01000013_gene3706 3.289e-91 303.0 COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,2TUWE@28211|Alphaproteobacteria,2JRQU@204441|Rhodospirillales 204441|Rhodospirillales J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase efp - - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C CMS1_k127_16181_0 414684.RC1_1824 2.836e-96 320.0 COG0352@1|root,COG0352@2|Bacteria,1MV42@1224|Proteobacteria,2TSSA@28211|Alphaproteobacteria,2JQJQ@204441|Rhodospirillales 204441|Rhodospirillales H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) thiE - 2.5.1.3 ko:K00788 ko00730,ko01100,map00730,map01100 M00127 R03223,R10712 RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 - - - TMP-TENI CMS1_k127_16181_2 1089552.KI911559_gene1621 7.56e-23 103.0 2EJ0G@1|root,332ZP@2|Bacteria,1N9QV@1224|Proteobacteria,2UJ4G@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_16181_3 331869.BAL199_17428 1.218e-09 61.0 COG0782@1|root,COG0782@2|Bacteria,1RAP0@1224|Proteobacteria,2U75V@28211|Alphaproteobacteria,4BRZM@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length greB - - ko:K04760 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N CMS1_k127_1629006_1 1038859.AXAU01000007_gene5816 2.641e-117 382.0 COG0477@1|root,COG2814@2|Bacteria,1MVKJ@1224|Proteobacteria,2TUK5@28211|Alphaproteobacteria,3JQXB@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria EGP Sugar (and other) transporter MA20_39450 - - - - - - - - - - - Sugar_tr CMS1_k127_1629006_3 1197906.CAJQ02000011_gene734 1.923e-45 175.0 COG3672@1|root,COG3672@2|Bacteria,1RDQS@1224|Proteobacteria,2TTZT@28211|Alphaproteobacteria,3JVGR@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Bacterial transglutaminase-like cysteine proteinase BTLCP - - - - - - - - - - - - Peptidase_C93 CMS1_k127_1629006_5 314231.FP2506_03054 9.979e-15 83.0 2B9G4@1|root,322U3@2|Bacteria,1P0JW@1224|Proteobacteria,2UEFE@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_1629006_2 883078.HMPREF9695_04139 1.116e-80 284.0 COG5330@1|root,COG5330@2|Bacteria,1R3VY@1224|Proteobacteria,2TUGG@28211|Alphaproteobacteria,3JUE9@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Uncharacterised protein conserved in bacteria (DUF2336) MA20_43740 - - - - - - - - - - - DUF2336 CMS1_k127_1629006_4 715226.ABI_39770 2.472e-27 115.0 COG0745@1|root,COG0745@2|Bacteria,1RDNP@1224|Proteobacteria,2U7BP@28211|Alphaproteobacteria,2KGQS@204458|Caulobacterales 204458|Caulobacterales T Chemotaxis regulator that, when phosphorylated, interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble - - - ko:K03413 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - Response_reg CMS1_k127_1629006_0 323097.Nham_2631 4.07e-185 584.0 COG0433@1|root,COG0433@2|Bacteria,1MU59@1224|Proteobacteria,2TRU8@28211|Alphaproteobacteria,3JRPZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Bacterial protein of unknown function (DUF853) yjgR - - ko:K06915 - - - - ko00000 - - - DUF853 CMS1_k127_164511_2 754035.Mesau_05725 8.226e-05 45.0 COG1396@1|root,COG1396@2|Bacteria 2|Bacteria K sequence-specific DNA binding - - - - - - - - - - - - HTH_19,HTH_3,HTH_31,TPR_12,TPR_16,TPR_8 CMS1_k127_164511_0 1205680.CAKO01000002_gene2378 8.921e-109 361.0 COG2175@1|root,COG2175@2|Bacteria,1MVI6@1224|Proteobacteria,2TVHF@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q PFAM Taurine catabolism dioxygenase TauD, TfdA family - - - ko:K06912 ko00361,ko01120,ko01220,map00361,map01120,map01220 - R05419,R05493 RC01371,RC01372 ko00000,ko00001,ko01000 - - - TauD CMS1_k127_164511_1 991905.SL003B_0366 4.041e-59 213.0 COG0730@1|root,COG0730@2|Bacteria,1RAG9@1224|Proteobacteria,2VEQZ@28211|Alphaproteobacteria,4BQPH@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria S Sulfite exporter TauE/SafE - - - - - - - - - - - - TauE CMS1_k127_1662703_2 1469245.JFBG01000002_gene450 2.172e-32 132.0 COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,1S8RG@1236|Gammaproteobacteria,1WYG6@135613|Chromatiales 135613|Chromatiales M Belongs to the ompA family - - - ko:K03640 - - - - ko00000,ko02000 2.C.1.2 - - OmpA CMS1_k127_1662703_1 713586.KB900536_gene1044 4.369e-50 187.0 COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,1RQWA@1236|Gammaproteobacteria,1WW2G@135613|Chromatiales 135613|Chromatiales D Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division cpoB - - - - - - - - - - - TPR_16,TPR_6,TolA_bind_tri,YfiO CMS1_k127_1662703_0 396588.Tgr7_2226 1.049e-95 318.0 COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,1RNQZ@1236|Gammaproteobacteria,1WW37@135613|Chromatiales 135613|Chromatiales O Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds queE - 4.3.99.3 ko:K10026 ko00790,ko01100,map00790,map01100 - R10002 RC02989 ko00000,ko00001,ko01000,ko03016 - - - Fer4_14,Radical_SAM CMS1_k127_1662703_3 565045.NOR51B_1291 1.062e-10 64.0 COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,1RMG9@1236|Gammaproteobacteria,1J4T0@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) queC - 6.3.4.20 ko:K06920 ko00790,ko01100,map00790,map01100 - R09978 RC00959 ko00000,ko00001,ko01000,ko03016 - - - QueC CMS1_k127_170115_3 1187851.A33M_0317 2.914e-16 80.0 COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,2TRIG@28211|Alphaproteobacteria,3FD76@34008|Rhodovulum 28211|Alphaproteobacteria K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate CMS1_k127_170115_0 224911.27354891 9.479e-103 342.0 COG3023@1|root,COG3023@2|Bacteria,1RDHU@1224|Proteobacteria,2TSW3@28211|Alphaproteobacteria,3JSSX@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria V N-acetylmuramoyl-L-alanine amidase (Family 2) amiD - 3.5.1.28 ko:K01447,ko:K03806 - - R04112 RC00064,RC00141 ko00000,ko01000,ko01011 - - - Amidase_2,PG_binding_1 CMS1_k127_170115_2 1187851.A33M_0312 8.269e-64 223.0 COG2001@1|root,COG2001@2|Bacteria,1RHCG@1224|Proteobacteria,2UD3W@28211|Alphaproteobacteria,3FDIE@34008|Rhodovulum 28211|Alphaproteobacteria K MraZ protein, putative antitoxin-like mraZ - - ko:K03925 - - - - ko00000 - - - MraZ CMS1_k127_170115_1 1038860.AXAP01000065_gene3598 5.377e-77 273.0 COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,2TRQA@28211|Alphaproteobacteria,3JT8T@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 - - - - ko00000,ko01000,ko03009 - - - Methyltransf_5 CMS1_k127_170771_1 1040989.AWZU01000036_gene7251 3.265e-261 818.0 COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,2TQYK@28211|Alphaproteobacteria,3JRUG@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA - 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N CMS1_k127_170771_2 1245469.S58_04230 3.328e-78 265.0 COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,2U5IC@28211|Alphaproteobacteria,3JSRB@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpH - - ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - OSCP CMS1_k127_170771_3 1144342.PMI40_00367 2.174e-73 263.0 COG0697@1|root,COG0697@2|Bacteria,1NEYM@1224|Proteobacteria,2VIII@28216|Betaproteobacteria 28216|Betaproteobacteria EG of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA CMS1_k127_170771_4 1144342.PMI40_00367 2.94e-68 252.0 COG0697@1|root,COG0697@2|Bacteria,1NEYM@1224|Proteobacteria,2VIII@28216|Betaproteobacteria 28216|Betaproteobacteria EG of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA CMS1_k127_170771_0 652103.Rpdx1_0458 0.0 1120.0 COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,2TQTQ@28211|Alphaproteobacteria,3JSST@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA - - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C CMS1_k127_1720617_1 1380394.JADL01000001_gene2539 6.989e-59 211.0 COG0607@1|root,COG2897@1|root,COG0607@2|Bacteria,COG2897@2|Bacteria,1MU3V@1224|Proteobacteria,2TSGP@28211|Alphaproteobacteria,2JR05@204441|Rhodospirillales 204441|Rhodospirillales P Rhodanese Homology Domain - - - - - - - - - - - - Rhodanese CMS1_k127_1720617_0 1211115.ALIQ01000171_gene4076 9.09e-98 328.0 COG0697@1|root,COG0697@2|Bacteria,1MXVF@1224|Proteobacteria,2TU7N@28211|Alphaproteobacteria,3N9WI@45404|Beijerinckiaceae 28211|Alphaproteobacteria EG EamA-like transporter family sam - - ko:K15270 - - - - ko00000,ko02000 2.A.7.3.7 - - EamA CMS1_k127_1720617_2 288000.BBta_0423 5.549e-28 115.0 COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,2TR5I@28211|Alphaproteobacteria,3JR6H@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control obg - - ko:K03979 - - - - ko00000,ko01000,ko03009 - - - GTP1_OBG,MMR_HSR1 CMS1_k127_172409_5 1038858.AXBA01000029_gene771 2.462e-85 284.0 COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,2TQWP@28211|Alphaproteobacteria,3EZ1F@335928|Xanthobacteraceae 28211|Alphaproteobacteria E Gamma-glutamyltranspeptidase - - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept CMS1_k127_172409_8 1038860.AXAP01000031_gene5707 3.573e-59 211.0 2E3CR@1|root,32YC0@2|Bacteria,1N9Q9@1224|Proteobacteria,2UF5B@28211|Alphaproteobacteria,3JYQP@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Nitrile hydratase beta subunit MA20_29595 - - - - - - - - - - - NHase_beta CMS1_k127_172409_4 1380355.JNIJ01000013_gene452 4.5e-103 342.0 28I45@1|root,2Z87Q@2|Bacteria,1R432@1224|Proteobacteria,2U3PK@28211|Alphaproteobacteria,3JS7H@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E NHase catalyzes the hydration of various nitrile compounds to the corresponding amides nthB - 4.2.1.84 ko:K20807 ko00364,ko00380,ko00627,ko00643,ko01120,map00364,map00380,map00627,map00643,map01120 - R04020,R05379,R05596,R07780,R07854 RC00483,RC01345,RC01432 ko00000,ko00001,ko01000 - - - NHase_beta CMS1_k127_172409_2 1297863.APJF01000038_gene1769 8.221e-118 380.0 2BZ0R@1|root,2Z7U0@2|Bacteria,1MX37@1224|Proteobacteria,2TSBD@28211|Alphaproteobacteria,3JT2X@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Nitrile hydratase, alpha chain nthA - 4.2.1.84 ko:K01721 ko00364,ko00380,ko00627,ko00643,ko01120,map00364,map00380,map00627,map00643,map01120 - R02828,R04020,R05379,R05596,R07780,R07854 RC00483,RC00792,RC01345,RC01432 ko00000,ko00001,ko01000 - - - NHase_alpha CMS1_k127_172409_9 1187851.A33M_1848 2.586e-45 169.0 COG4665@1|root,COG4665@2|Bacteria,1PJN9@1224|Proteobacteria,2V8T6@28211|Alphaproteobacteria,3FEH7@34008|Rhodovulum 28211|Alphaproteobacteria Q Tripartite ATP-independent periplasmic transporters, DctQ component - - - - - - - - - - - - DctQ CMS1_k127_172409_1 1187851.A33M_1847 2.243e-175 562.0 COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,2TQNR@28211|Alphaproteobacteria,3FCVW@34008|Rhodovulum 28211|Alphaproteobacteria Q Tripartite ATP-independent periplasmic transporter, DctM component - - - - - - - - - - - - DctM CMS1_k127_172409_3 566466.NOR53_1646 1.97e-107 355.0 COG0625@1|root,COG0625@2|Bacteria,1R6UY@1224|Proteobacteria,1RY70@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Glutathione S-transferase, C-terminal domain - - - - - - - - - - - - GST_C,GST_C_2,GST_N_3 CMS1_k127_172409_6 1120956.JHZK01000008_gene571 1.489e-75 261.0 COG1028@1|root,COG1028@2|Bacteria,1MXWI@1224|Proteobacteria,2TQQ6@28211|Alphaproteobacteria,1JP45@119043|Rhodobiaceae 28211|Alphaproteobacteria IQ KR domain - - 1.1.1.127 ko:K00065 ko00040,map00040 - R01542 RC00089 ko00000,ko00001,ko01000 - - - adh_short_C2 CMS1_k127_172409_0 909943.HIMB100_00021040 6.204e-192 605.0 COG1960@1|root,COG1960@2|Bacteria,1MU2V@1224|Proteobacteria,2TSK3@28211|Alphaproteobacteria,4BPRD@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria I Acyl-CoA dehydrogenase, C-terminal domain - - 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N CMS1_k127_172409_17 1248760.ANFZ01000002_gene2984 1.699e-06 60.0 COG2885@1|root,COG2885@2|Bacteria,1NABG@1224|Proteobacteria,2VFV3@28211|Alphaproteobacteria,2KDZS@204457|Sphingomonadales 204457|Sphingomonadales M OmpA family - - - - - - - - - - - - OmpA CMS1_k127_172409_16 1144343.PMI41_00150 1.045e-06 55.0 COG3103@1|root,COG4991@2|Bacteria,1N1DV@1224|Proteobacteria,2UER1@28211|Alphaproteobacteria,43KNZ@69277|Phyllobacteriaceae 28211|Alphaproteobacteria T sh3 domain protein - - - - - - - - - - - - - CMS1_k127_172409_18 652103.Rpdx1_2871 3.375e-05 50.0 2B8MF@1|root,321WS@2|Bacteria,1N4A0@1224|Proteobacteria,2UCWJ@28211|Alphaproteobacteria,3K02W@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_172409_7 196490.AUEZ01000047_gene6720 5.003e-74 254.0 COG1376@1|root,COG1376@2|Bacteria,1MVYT@1224|Proteobacteria,2TUXV@28211|Alphaproteobacteria,3JUKK@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S L,D-transpeptidase catalytic domain - - - - - - - - - - - - YkuD CMS1_k127_172409_11 1038858.AXBA01000001_gene3141 2.206e-26 113.0 COG0797@1|root,COG0797@2|Bacteria,1MZ8S@1224|Proteobacteria,2UBTC@28211|Alphaproteobacteria,3EZZF@335928|Xanthobacteraceae 28211|Alphaproteobacteria M Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - ko:K03642 - - - - ko00000 - - - DPBB_1 CMS1_k127_172409_15 335659.S23_52010 3.408e-12 72.0 2AD3C@1|root,312RN@2|Bacteria,1N4AJ@1224|Proteobacteria,2UCDU@28211|Alphaproteobacteria,3K0EN@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_172409_12 1038858.AXBA01000001_gene3185 7.793e-24 105.0 COG5490@1|root,COG5490@2|Bacteria,1RAUN@1224|Proteobacteria,2U5EB@28211|Alphaproteobacteria,3EZPR@335928|Xanthobacteraceae 28211|Alphaproteobacteria S Phasin protein - - - - - - - - - - - - Phasin_2 CMS1_k127_172409_14 1037409.BJ6T_31870 1.713e-18 90.0 2E46N@1|root,32Z2M@2|Bacteria,1N6SH@1224|Proteobacteria,2UHDJ@28211|Alphaproteobacteria,3K55U@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_172409_10 1380394.JADL01000013_gene701 3.843e-34 132.0 COG5496@1|root,COG5496@2|Bacteria,1RKFT@1224|Proteobacteria,2U5DE@28211|Alphaproteobacteria,2JUSB@204441|Rhodospirillales 204441|Rhodospirillales S Thioesterase - - 3.1.2.29 ko:K18700 - - - - ko00000,ko01000 - - - 4HBT CMS1_k127_1746176_10 1123229.AUBC01000005_gene759 1.373e-13 76.0 COG1018@1|root,COG1600@1|root,COG1018@2|Bacteria,COG1600@2|Bacteria,1MU6E@1224|Proteobacteria,2TRE9@28211|Alphaproteobacteria,3JSXZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C 2Fe-2S iron-sulfur cluster binding domain vanB - - ko:K03863 ko00627,ko01120,map00627,map01120 - R05274 RC00392,RC01533 ko00000,ko00001 - - - Dehalogenase,FAD_binding_6,Fer2,Fer4_16,Fer4_7,NAD_binding_1 CMS1_k127_1746176_7 258594.RPA3704 4.217e-44 161.0 COG2827@1|root,COG2827@2|Bacteria,1MZME@1224|Proteobacteria,2UCNX@28211|Alphaproteobacteria,3JZIP@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L Excinuclease ABC, C subunit - - - ko:K07461 - - - - ko00000 - - - GIY-YIG CMS1_k127_1746176_0 1297863.APJF01000013_gene3932 0.0 1102.0 COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,2TRHK@28211|Alphaproteobacteria,3JVTG@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA ligA GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2 CMS1_k127_1746176_4 1429916.X566_15275 2.199e-91 316.0 COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,2TRQD@28211|Alphaproteobacteria,3JSD8@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria EGP drug resistance transporter, Bcr CflA MA20_01870 - - ko:K07552 - - - - ko00000,ko02000 2.A.1.2 - - MFS_1 CMS1_k127_1746176_1 1187851.A33M_3120 9.152e-258 809.0 COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,2TQXN@28211|Alphaproteobacteria,3FCQZ@34008|Rhodovulum 28211|Alphaproteobacteria E Creatinase/Prolidase N-terminal domain pepP - 3.4.11.9 ko:K01262 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C CMS1_k127_1746176_6 1232410.KI421422_gene1940 1.932e-74 263.0 COG1638@1|root,COG1638@2|Bacteria,1MVHI@1224|Proteobacteria,42MVD@68525|delta/epsilon subdivisions,2WIY3@28221|Deltaproteobacteria,43U0W@69541|Desulfuromonadales 28221|Deltaproteobacteria G Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP CMS1_k127_1746176_8 376733.IT41_11230 1.57e-30 127.0 COG3090@1|root,COG3090@2|Bacteria,1N9D4@1224|Proteobacteria,2U7Z5@28211|Alphaproteobacteria,2PX1A@265|Paracoccus 28211|Alphaproteobacteria G Tripartite ATP-independent periplasmic transporters, DctQ component - - - - - - - - - - - - DctQ CMS1_k127_1746176_2 331869.BAL199_10697 3.372e-147 481.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQNK@28211|Alphaproteobacteria,4BR75@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria G COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - - - - - - - - - - DctM CMS1_k127_1746176_3 1123060.JONP01000002_gene1011 3.99e-137 447.0 COG0654@1|root,COG0654@2|Bacteria,1MWWT@1224|Proteobacteria,2TRZP@28211|Alphaproteobacteria,2JU43@204441|Rhodospirillales 204441|Rhodospirillales CH FAD binding domain - - - - - - - - - - - - FAD_binding_3 CMS1_k127_1746176_5 1429916.X566_15290 4.033e-87 297.0 COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,2TTP3@28211|Alphaproteobacteria,3JR3H@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Ribosomal protein L11 methyltransferase prmA - - ko:K02687 - - - - ko00000,ko01000,ko03009 - - - PrmA CMS1_k127_1746176_9 1040987.AZUY01000062_gene5320 1.12e-14 85.0 2DKUM@1|root,30DC7@2|Bacteria,1RDKZ@1224|Proteobacteria,2U8IU@28211|Alphaproteobacteria,43JHW@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Hemerythrin HHE cation binding domain - - - - - - - - - - - - Hemerythrin CMS1_k127_1780753_9 123899.JPQP01000022_gene3429 3.424e-24 103.0 COG0624@1|root,COG0624@2|Bacteria,1MW20@1224|Proteobacteria,2VHV4@28216|Betaproteobacteria,3T5P0@506|Alcaligenaceae 28216|Betaproteobacteria E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases - - - - - - - - - - - - M20_dimer,Peptidase_M20 CMS1_k127_1780753_13 1161401.ASJA01000002_gene2590 0.0001483 48.0 COG4530@1|root,COG4530@2|Bacteria,1PVIW@1224|Proteobacteria,2V6XG@28211|Alphaproteobacteria,43YHS@69657|Hyphomonadaceae 28211|Alphaproteobacteria S Protein of unknown function (FYDLN_acid) - - - - - - - - - - - - FYDLN_acid CMS1_k127_1780753_8 1205680.CAKO01000024_gene4503 2.003e-29 121.0 2EM0K@1|root,33EQ3@2|Bacteria,1NIHC@1224|Proteobacteria,2UMWX@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_1780753_2 570952.ATVH01000014_gene2235 1.516e-116 384.0 COG1305@1|root,COG1305@2|Bacteria,1MWAI@1224|Proteobacteria,2TURT@28211|Alphaproteobacteria,2JQTU@204441|Rhodospirillales 204441|Rhodospirillales E Transglutaminase-like superfamily - - - - - - - - - - - - Transglut_core CMS1_k127_1780753_14 1205680.CAKO01000005_gene3546 0.0004353 44.0 COG0624@1|root,COG0624@2|Bacteria,1MW20@1224|Proteobacteria,2TTGM@28211|Alphaproteobacteria,2JPI4@204441|Rhodospirillales 204441|Rhodospirillales E Peptidase family M20/M25/M40 - - - - - - - - - - - - M20_dimer,Peptidase_M20 CMS1_k127_1780753_5 411902.CLOBOL_02063 2.311e-84 297.0 COG1073@1|root,COG1073@2|Bacteria,1TRSD@1239|Firmicutes 1239|Firmicutes S Belongs to the UPF0255 family - - - - - - - - - - - - DUF1100 CMS1_k127_1780753_1 1248916.ANFY01000007_gene2486 3.773e-134 441.0 COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,2TTWK@28211|Alphaproteobacteria,2K0DU@204457|Sphingomonadales 204457|Sphingomonadales E Methionine synthase - - - - - - - - - - - - Meth_synt_2 CMS1_k127_1780753_7 1123355.JHYO01000017_gene3573 5.473e-53 193.0 COG1309@1|root,COG1309@2|Bacteria,1N0XU@1224|Proteobacteria,2U82V@28211|Alphaproteobacteria,36YQ2@31993|Methylocystaceae 28211|Alphaproteobacteria K WHG domain - - - - - - - - - - - - TetR_N,WHG CMS1_k127_1780753_0 1210884.HG799466_gene12511 3.509e-154 506.0 COG1032@1|root,COG1032@2|Bacteria,2IYYP@203682|Planctomycetes 203682|Planctomycetes C B12 binding domain - - - - - - - - - - - - B12-binding,DUF4070,Radical_SAM CMS1_k127_1780753_6 1089552.KI911559_gene1439 3.439e-75 264.0 COG1192@1|root,COG1192@2|Bacteria,1MVKR@1224|Proteobacteria,2TRZY@28211|Alphaproteobacteria,2JP8S@204441|Rhodospirillales 204441|Rhodospirillales D COG1192 ATPases involved in chromosome partitioning - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - MipZ CMS1_k127_1780753_12 313612.L8106_07641 2.755e-07 59.0 COG0515@1|root,COG0515@2|Bacteria,1GA7B@1117|Cyanobacteria,1HCYX@1150|Oscillatoriales 1117|Cyanobacteria KLT Domain of unknown function (DUF4189) - - - - - - - - - - - - DUF4189 CMS1_k127_1780753_3 1430440.MGMSRv2_2149 2.628e-99 347.0 COG0642@1|root,COG0642@2|Bacteria,1MX6R@1224|Proteobacteria,2TS9N@28211|Alphaproteobacteria,2JPH2@204441|Rhodospirillales 204441|Rhodospirillales T Histidine kinase-like ATPases - - - - - - - - - - - - HATPase_c CMS1_k127_1780753_4 1316936.K678_06118 1.382e-86 297.0 COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,2TSV8@28211|Alphaproteobacteria,2JYKR@204441|Rhodospirillales 204441|Rhodospirillales T Transcriptional regulatory protein, C terminal - - - ko:K02483 - - - - ko00000,ko02022 - - - Response_reg,Trans_reg_C CMS1_k127_1780753_11 1003200.AXXA_04443 5.343e-13 73.0 COG3212@1|root,COG3212@2|Bacteria,1NHDB@1224|Proteobacteria,2VWE0@28216|Betaproteobacteria,3T51X@506|Alcaligenaceae 28216|Betaproteobacteria S Peptidase propeptide and ypeb - - - - - - - - - - - - PepSY CMS1_k127_1780753_10 1463936.JOJI01000026_gene3333 2.871e-20 95.0 COG1073@1|root,COG1073@2|Bacteria,2GK5B@201174|Actinobacteria 201174|Actinobacteria S Alpha/beta hydrolase of unknown function (DUF1100) - - - - - - - - - - - - DUF1100 CMS1_k127_1807044_0 1429916.X566_08215 0.0 1433.0 COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,2TRBQ@28211|Alphaproteobacteria,3JRD5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C E1 component sucA - 1.2.4.2 ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R00621,R01933,R01940,R03316,R08549 RC00004,RC00027,RC00627,RC02743,RC02833,RC02883 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr CMS1_k127_1807044_3 1411123.JQNH01000001_gene103 2.256e-167 528.0 COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,2TQKB@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit sucD - 6.2.1.5 ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - CoA_binding,Ligase_CoA CMS1_k127_1807044_1 1187851.A33M_0594 2.78e-183 580.0 COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,2TRXK@28211|Alphaproteobacteria,3FCJK@34008|Rhodovulum 28211|Alphaproteobacteria F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit sucC GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 6.2.1.5 ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp_2,Ligase_CoA CMS1_k127_1807044_2 1197906.CAJQ02000029_gene3895 8.297e-174 550.0 COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,2TSV6@28211|Alphaproteobacteria,3JRQU@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Catalyzes the reversible oxidation of malate to oxaloacetate mdh GO:0003674,GO:0003824,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0030060,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.37 ko:K00024 ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740 R00342,R07136 RC00031 ko00000,ko00001,ko00002,ko01000 - - - Ldh_1_C,Ldh_1_N CMS1_k127_1807044_4 1298867.AUES01000036_gene2350 1.488e-26 109.0 COG1485@1|root,COG1485@2|Bacteria,1MUUW@1224|Proteobacteria,2TRG1@28211|Alphaproteobacteria,3JRCC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S AFG1-like ATPase zapE GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0006091,GO:0006119,GO:0006123,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007005,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016310,GO:0017144,GO:0019538,GO:0019637,GO:0019646,GO:0019693,GO:0022900,GO:0022904,GO:0030163,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0035694,GO:0042773,GO:0042775,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071840,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901565,GO:1901575 - ko:K06916 - - - - ko00000,ko03036 - - - AFG1_ATPase CMS1_k127_1810671_2 1187851.A33M_3034 1.929e-67 245.0 COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,2V870@28211|Alphaproteobacteria,3FEFS@34008|Rhodovulum 28211|Alphaproteobacteria S Patatin-like phospholipase - - - - - - - - - - - - Patatin CMS1_k127_1810671_0 1411123.JQNH01000001_gene241 1.268e-152 490.0 COG3173@1|root,COG3173@2|Bacteria,1MWAK@1224|Proteobacteria,2TT2N@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Aminoglycoside phosphotransferase - - - - - - - - - - - - APH CMS1_k127_1810671_1 189753.AXAS01000010_gene7220 1.95e-75 260.0 2ER8M@1|root,33IU6@2|Bacteria,1NBUC@1224|Proteobacteria,2UFGX@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_1810671_3 1187851.A33M_3035 3.304e-20 91.0 COG0596@1|root,COG0596@2|Bacteria,1MUVB@1224|Proteobacteria,2TREP@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Alpha beta hydrolase MA20_05720 - 3.8.1.3 ko:K01561 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05287 RC00697 ko00000,ko00001,ko01000 - - - Abhydrolase_1 CMS1_k127_1811560_1 883078.HMPREF9695_00095 5.318e-75 258.0 COG2096@1|root,COG2096@2|Bacteria,1RDUF@1224|Proteobacteria,2U5J1@28211|Alphaproteobacteria,3JS3E@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Cobalamin adenosyltransferase MA20_20540 - 2.5.1.17 ko:K00798 ko00860,ko01100,map00860,map01100 M00122 R01492,R05220,R07268 RC00533 ko00000,ko00001,ko00002,ko01000 - - - Cob_adeno_trans CMS1_k127_1811560_0 1131814.JAFO01000001_gene266 1.504e-132 426.0 COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,2TR4J@28211|Alphaproteobacteria,3EYZA@335928|Xanthobacteraceae 28211|Alphaproteobacteria C Electron transfer flavoprotein domain etfB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114 - ko:K03521 - - - - ko00000 - - - ETF CMS1_k127_1814037_0 247633.GP2143_11639 5.092e-140 454.0 COG2358@1|root,COG2358@2|Bacteria,1R3ZR@1224|Proteobacteria,1RVRS@1236|Gammaproteobacteria 1236|Gammaproteobacteria S transport system periplasmic component - - - - - - - - - - - - NMT1_3 CMS1_k127_1814037_1 1242864.D187_006233 4.219e-94 317.0 COG1414@1|root,COG1414@2|Bacteria,1PFIS@1224|Proteobacteria,43A8I@68525|delta/epsilon subdivisions,2X28Q@28221|Deltaproteobacteria,2Z2MT@29|Myxococcales 28221|Deltaproteobacteria K helix_turn_helix isocitrate lyase regulation - - - ko:K02624 - - - - ko00000,ko03000 - - - HTH_IclR,IclR CMS1_k127_1814037_2 78245.Xaut_2056 5.794e-12 68.0 COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,2TRKB@28211|Alphaproteobacteria,3EZ65@335928|Xanthobacteraceae 28211|Alphaproteobacteria E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate proB GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 M00015 R00239 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,PUA CMS1_k127_1814608_1 1187851.A33M_1148 2.026e-205 651.0 COG0802@1|root,COG3178@1|root,COG0802@2|Bacteria,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,2TSJD@28211|Alphaproteobacteria,3FD30@34008|Rhodovulum 28211|Alphaproteobacteria S Phosphotransferase enzyme family MA20_24090 - 2.7.1.221 ko:K07102 ko00520,ko01100,map00520,map01100 - R08968,R11024 RC00002,RC00078 ko00000,ko00001,ko01000 - - - APH,TsaE CMS1_k127_1814608_2 258594.RPA0076 1.671e-102 344.0 COG1208@1|root,COG1208@2|Bacteria,1R9ZD@1224|Proteobacteria,2TU2V@28211|Alphaproteobacteria,3JRYE@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria JM Nucleotidyl transferase MA20_24100 - 2.7.7.13,2.7.7.99 ko:K00966,ko:K00992 ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110 M00114,M00361,M00362 R00885,R11025 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transf_3,NTP_transferase CMS1_k127_1814608_0 1187851.A33M_1979 0.0 1086.0 COG2887@1|root,COG3893@1|root,COG2887@2|Bacteria,COG3893@2|Bacteria,1MY2G@1224|Proteobacteria,2TS74@28211|Alphaproteobacteria,3FCKT@34008|Rhodovulum 28211|Alphaproteobacteria L PD-(D/E)XK nuclease superfamily addB - 3.6.4.12 ko:K16899 - - - - ko00000,ko01000,ko03400 - - - PDDEXK_1 CMS1_k127_1814608_3 114615.BRADO0084 2.697e-39 153.0 COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,2TQJZ@28211|Alphaproteobacteria,3JSGA@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L Belongs to the helicase family. UvrD subfamily addA - 3.6.4.12 ko:K16898 - - - - ko00000,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C CMS1_k127_1822061_8 1187848.AJYQ01000032_gene2249 4.167e-05 49.0 COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RMQQ@1236|Gammaproteobacteria,1XSYI@135623|Vibrionales 135623|Vibrionales H COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase ilvI - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N CMS1_k127_1822061_3 1034347.CAHJ01000023_gene3260 7.147e-39 162.0 COG1638@1|root,COG1638@2|Bacteria,1TP3I@1239|Firmicutes,4HD0U@91061|Bacilli,1ZCY6@1386|Bacillus 91061|Bacilli G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - - - - - - - - - - DctP CMS1_k127_1822061_5 1395587.P364_0120850 7.749e-20 102.0 COG0673@1|root,COG0673@2|Bacteria,1TQ72@1239|Firmicutes,4HAGN@91061|Bacilli,26RKY@186822|Paenibacillaceae 91061|Bacilli S Oxidoreductase - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C CMS1_k127_1822061_2 1502851.FG93_04754 4.367e-39 162.0 COG4655@1|root,COG4655@2|Bacteria,1RGJG@1224|Proteobacteria,2U32U@28211|Alphaproteobacteria 28211|Alphaproteobacteria U Putative Flp pilus-assembly TadE/G-like - - - - - - - - - - - - Tad CMS1_k127_1822061_7 426117.M446_5904 3.822e-07 57.0 COG4961@1|root,COG4961@2|Bacteria,1PPJ4@1224|Proteobacteria,2V20V@28211|Alphaproteobacteria,1JXX1@119045|Methylobacteriaceae 28211|Alphaproteobacteria U PFAM TadE family protein - - - - - - - - - - - - TadE CMS1_k127_1822061_0 1040989.AWZU01000002_gene5330 4.402e-202 643.0 COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,2TQKQ@28211|Alphaproteobacteria,3JSS3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E GMC oxidoreductase MA20_44990 - 1.1.99.1 ko:K00108 ko00260,ko01100,map00260,map01100 M00555 R01025 RC00087 ko00000,ko00001,ko00002,ko01000 - - - GMC_oxred_C,GMC_oxred_N CMS1_k127_1822061_1 1565314.OA34_11340 2.715e-43 160.0 COG4679@1|root,COG4679@2|Bacteria,1MZ3N@1224|Proteobacteria,42TST@68525|delta/epsilon subdivisions 1224|Proteobacteria S Phage derived protein Gp49-like (DUF891) - - - - - - - - - - - - Gp49 CMS1_k127_1822061_4 426117.M446_7032 7.558e-28 116.0 COG3093@1|root,COG3093@2|Bacteria,1NA48@1224|Proteobacteria,2UGHZ@28211|Alphaproteobacteria,1JYXA@119045|Methylobacteriaceae 28211|Alphaproteobacteria K Helix-turn-helix domain - - - - - - - - - - - - HTH_37 CMS1_k127_1822061_6 639283.Snov_0185 2.486e-08 56.0 COG0673@1|root,COG0673@2|Bacteria 2|Bacteria S inositol 2-dehydrogenase activity - - - ko:K18106 ko00040,ko01100,map00040,map01100 M00630 R07676,R10565 RC00108 ko00000,ko00001,ko00002,ko01000 - - - GFO_IDH_MocA,GFO_IDH_MocA_C CMS1_k127_1823541_0 1244869.H261_05239 6.285e-168 532.0 COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,2VF1V@28211|Alphaproteobacteria 28211|Alphaproteobacteria C COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing - - - - - - - - - - - - FAD_binding_6,Fer2,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NAD_binding_1 CMS1_k127_1823541_1 1244869.H261_19923 2.075e-104 348.0 COG0583@1|root,COG0583@2|Bacteria,1P2I1@1224|Proteobacteria,2UDDD@28211|Alphaproteobacteria,2JXCP@204441|Rhodospirillales 204441|Rhodospirillales K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate CMS1_k127_1823541_2 1244869.H261_19918 8.5e-44 166.0 COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,2TSAP@28211|Alphaproteobacteria,2JRAB@204441|Rhodospirillales 204441|Rhodospirillales C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - - - - - - - - - - Molybdopterin,Molydop_binding CMS1_k127_1828323_0 639283.Snov_2529 0.0 1144.0 COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2TSN5@28211|Alphaproteobacteria,3EY0Y@335928|Xanthobacteraceae 28211|Alphaproteobacteria C FAD linked oxidases, C-terminal domain MA20_43170 - - - - - - - - - - - CCG,FAD-oxidase_C,FAD_binding_4,Fer4_8 CMS1_k127_1828323_1 1248917.ANFX01000040_gene766 1.706e-178 568.0 COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,2TTWK@28211|Alphaproteobacteria,2K3CA@204457|Sphingomonadales 204457|Sphingomonadales E Cobalamin-independent synthase, Catalytic domain - - - - - - - - - - - - Meth_synt_2 CMS1_k127_1828323_2 1394178.AWOO02000004_gene2433 1.043e-97 327.0 COG0500@1|root,COG2226@2|Bacteria,2GNTH@201174|Actinobacteria 201174|Actinobacteria Q methyltransferase - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 CMS1_k127_1828323_4 1121939.L861_17290 2.631e-61 222.0 COG1733@1|root,COG1733@2|Bacteria,1NEKW@1224|Proteobacteria,1RYP5@1236|Gammaproteobacteria,1XRI6@135619|Oceanospirillales 135619|Oceanospirillales K HxlR-like helix-turn-helix - - - - - - - - - - - - HxlR CMS1_k127_1828323_3 1248916.ANFY01000007_gene2487 1.48e-61 215.0 COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,2TTWK@28211|Alphaproteobacteria,2K3CA@204457|Sphingomonadales 204457|Sphingomonadales E Cobalamin-independent synthase, Catalytic domain - - - - - - - - - - - - Meth_synt_2 CMS1_k127_1831061_1 1187851.A33M_0290 2.953e-155 502.0 COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,2TU12@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose hldE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046835,GO:0071704 2.7.1.167,2.7.7.70 ko:K03272 ko00540,ko01100,map00540,map01100 M00064 R05644,R05646 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CTP_transf_like,PfkB CMS1_k127_1831061_0 443598.AUFA01000028_gene7171 1.806e-159 507.0 COG0451@1|root,COG0451@2|Bacteria,1MVE4@1224|Proteobacteria,2TQJI@28211|Alphaproteobacteria,3JU88@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria GM Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose hldD - 5.1.3.2,5.1.3.20 ko:K01784,ko:K03274 ko00052,ko00520,ko00540,ko01100,map00052,map00520,map00540,map01100 M00064,M00361,M00362,M00632 R00291,R02984,R05176 RC00289,RC01291 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Epimerase CMS1_k127_1831061_3 316056.RPC_1430 2.736e-116 384.0 COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,2TSXD@28211|Alphaproteobacteria,3JU3C@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Glycosyltransferase family 9 (heptosyltransferase) rfaF - - ko:K02843 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 CMS1_k127_1831061_2 316058.RPB_4539 2.056e-135 440.0 COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,2TU5X@28211|Alphaproteobacteria,3JR9G@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Belongs to the SIS family. GutQ KpsF subfamily kdsD - 5.3.1.13 ko:K06041 ko00540,ko01100,map00540,map01100 M00063 R01530 RC00541 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CBS,SIS CMS1_k127_1831061_4 1187851.A33M_0287 5.249e-81 275.0 COG0859@1|root,COG0859@2|Bacteria,1MYZA@1224|Proteobacteria,2U0ZB@28211|Alphaproteobacteria 28211|Alphaproteobacteria M PFAM glycosyl transferase family 9 waaC - - ko:K02841 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 CMS1_k127_183180_6 450851.PHZ_p0154 5.612e-79 271.0 COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,2TR2P@28211|Alphaproteobacteria,2KK9G@204458|Caulobacterales 204458|Caulobacterales V AAA domain, putative AbiEii toxin, Type IV TA system - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran CMS1_k127_183180_5 450851.PHZ_p0153 5.214e-82 283.0 COG1566@1|root,COG1566@2|Bacteria,1QU7Z@1224|Proteobacteria,2TW9Z@28211|Alphaproteobacteria 28211|Alphaproteobacteria V secretion protein yhiI - - ko:K01993 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 CMS1_k127_183180_9 1177928.TH2_19939 5.1e-25 108.0 COG3462@1|root,COG3462@2|Bacteria,1NGXC@1224|Proteobacteria,2UKQ8@28211|Alphaproteobacteria,2JUIX@204441|Rhodospirillales 204441|Rhodospirillales S Short C-terminal domain - - - - - - - - - - - - SHOCT CMS1_k127_183180_4 1444711.CCJF01000003_gene87 6.679e-107 357.0 COG0462@1|root,COG0462@2|Bacteria 2|Bacteria F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) - - 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyltran,Pribosyltran_N CMS1_k127_183180_2 1297865.APJD01000017_gene4290 4.909e-200 635.0 COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,2TS24@28211|Alphaproteobacteria,3JQN1@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria F Thymidine phosphorylase - - 2.4.2.4 ko:K00758 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 - R01570,R02484,R08222,R08230 RC00063 ko00000,ko00001,ko01000 - - - Glycos_trans_3N,Glycos_transf_3,PYNP_C CMS1_k127_183180_1 570952.ATVH01000013_gene2690 5.07e-224 701.0 COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,2TVFM@28211|Alphaproteobacteria,2JRI1@204441|Rhodospirillales 204441|Rhodospirillales J exonuclease of the beta-lactamase fold involved in RNA processing - - - ko:K07576 - - - - ko00000 - - - Beta-Casp,Lactamase_B,RMMBL CMS1_k127_183180_8 1177928.TH2_19879 1.225e-48 178.0 COG1226@1|root,31669@2|Bacteria,1RIW0@1224|Proteobacteria,2VGPK@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Ion channel - - - - - - - - - - - - Ion_trans_2 CMS1_k127_183180_3 1280944.HY17_07590 6.107e-139 454.0 COG0644@1|root,COG0644@2|Bacteria,1R4JF@1224|Proteobacteria,2U0P0@28211|Alphaproteobacteria 28211|Alphaproteobacteria C COG0644 Dehydrogenases (flavoproteins) - - - - - - - - - - - - HI0933_like,NAD_binding_8 CMS1_k127_183180_0 1038866.KB902773_gene800 0.0 1137.0 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2TR80@28211|Alphaproteobacteria,3JQNW@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P ATPase, P-type (transporting), HAD superfamily, subfamily IC - - 3.6.3.54 ko:K17686,ko:K19597 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5,3.A.3.5.20 - - E1-E2_ATPase,HMA,Hydrolase CMS1_k127_183180_7 1282876.BAOK01000001_gene2741 5.611e-61 220.0 COG4633@1|root,COG4633@2|Bacteria,1N1UQ@1224|Proteobacteria,2UEDS@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Cupredoxin-like domain - - - - - - - - - - - - Cupredoxin_1 CMS1_k127_183180_11 631454.N177_0052 0.0002427 46.0 COG3391@1|root,COG3391@2|Bacteria,1P862@1224|Proteobacteria,2TV3X@28211|Alphaproteobacteria 28211|Alphaproteobacteria S TIGRFAM 40-residue YVTN family beta-propeller repeat protein - - - - - - - - - - - - Lactonase,PQQ_2 CMS1_k127_1837277_1 292415.Tbd_0748 3.307e-70 238.0 COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,2VRJN@28216|Betaproteobacteria 28216|Betaproteobacteria S associated with various cellular activities - - - - - - - - - - - - AAA,AAA_5 CMS1_k127_1837277_0 1123393.KB891317_gene2265 1.24e-243 754.0 COG3864@1|root,COG3864@2|Bacteria,1MY13@1224|Proteobacteria,2VS6Y@28216|Betaproteobacteria,1KSGS@119069|Hydrogenophilales 119069|Hydrogenophilales S Putative metallopeptidase domain - - - - - - - - - - - - DUF2201,DUF2201_N CMS1_k127_1845097_0 1040989.AWZU01000014_gene4494 3.614e-285 879.0 COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,2TRI1@28211|Alphaproteobacteria,3JTM9@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Carboxyl transferase domain pccB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0031974,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0070013,GO:0071704,GO:0072329,GO:1901575 2.1.3.15,6.4.1.3 ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 M00373,M00741 R01859 RC00097,RC00609 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans CMS1_k127_1845097_2 670292.JH26_01350 9.338e-143 460.0 COG2159@1|root,COG2159@2|Bacteria,1MXI7@1224|Proteobacteria,2U256@28211|Alphaproteobacteria,1JYIK@119045|Methylobacteriaceae 28211|Alphaproteobacteria S Amidohydrolase - - 4.2.1.83 ko:K10220 ko00362,ko01120,map00362,map01120 - R04478 RC00498 ko00000,ko00001,ko01000 - - - Amidohydro_2 CMS1_k127_1845097_8 1040983.AXAE01000036_gene1967 9.752e-35 137.0 2EE5U@1|root,3380C@2|Bacteria,1NFP0@1224|Proteobacteria,2UIKT@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - DUF4440 CMS1_k127_1845097_6 670292.JH26_08660 8.74e-51 185.0 COG3019@1|root,COG3019@2|Bacteria,1MZ9V@1224|Proteobacteria,2UC0B@28211|Alphaproteobacteria,1JUQH@119045|Methylobacteriaceae 28211|Alphaproteobacteria S Protein of unknown function, DUF - - - - - - - - - - - - DUF411 CMS1_k127_1845097_1 1469245.JFBG01000062_gene2271 1.277e-216 691.0 COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,1RMH7@1236|Gammaproteobacteria 1236|Gammaproteobacteria S TRAP transporter, 4TM 12TM fusion protein - - - - - - - - - - - - DctM CMS1_k127_1845097_3 713586.KB900536_gene844 2.129e-117 391.0 COG2358@1|root,COG2358@2|Bacteria,1NRSC@1224|Proteobacteria 1224|Proteobacteria S TRAP transporter, solute receptor (TAXI family - - - - - - - - - - - - NMT1_3 CMS1_k127_1845097_4 1123229.AUBC01000003_gene2029 1.899e-107 357.0 COG1712@1|root,COG1712@2|Bacteria,1MX8S@1224|Proteobacteria,2TV48@28211|Alphaproteobacteria,3JSWD@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate nadX - 1.4.1.21 ko:K06989 ko00760,ko01100,map00760,map01100 - R07407,R07410 RC02566 ko00000,ko00001,ko01000 - - - DUF108,NAD_binding_3 CMS1_k127_1845097_5 631454.N177_1749 8.643e-59 214.0 COG0517@1|root,COG0517@2|Bacteria,1NY5H@1224|Proteobacteria,2U1GG@28211|Alphaproteobacteria,1JQ6B@119043|Rhodobiaceae 28211|Alphaproteobacteria S BON domain - - - - - - - - - - - - BON,CBS CMS1_k127_1845097_10 316056.RPC_1188 3.401e-12 73.0 COG3182@1|root,COG3182@2|Bacteria,1QVAW@1224|Proteobacteria,2U1PP@28211|Alphaproteobacteria,3JUTK@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S PepSY-associated TM region - - - - - - - - - - - - PepSY_TM CMS1_k127_1845097_7 331869.BAL199_21269 3.327e-44 170.0 COG0387@1|root,COG0387@2|Bacteria,1MWD8@1224|Proteobacteria,2TS6S@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Sodium calcium exchanger membrane - - - ko:K07300 - - - - ko00000,ko02000 2.A.19 - - Na_Ca_ex CMS1_k127_1847130_2 258594.RPA2903 2.978e-14 73.0 COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,2TT7W@28211|Alphaproteobacteria,3JS89@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair lexA GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 ko:K01356 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - LexA_DNA_bind,Peptidase_S24 CMS1_k127_1847130_0 1197906.CAJQ02000011_gene579 7.887e-154 497.0 COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,2TQRI@28211|Alphaproteobacteria,3JRTS@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H MoeA C-terminal region (domain IV) moeA GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0042802,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.10.1.1 ko:K03750 ko00790,ko01100,map00790,map01100 - R09735 RC03462 ko00000,ko00001,ko01000 - - - MoCF_biosynth,MoeA_C,MoeA_N CMS1_k127_1847130_1 1131814.JAFO01000001_gene2369 8.464e-55 194.0 COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,2U747@28211|Alphaproteobacteria,3EZHK@335928|Xanthobacteraceae 28211|Alphaproteobacteria H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) moaC - 4.6.1.17 ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R11372 RC03425 ko00000,ko00001,ko01000 - - - MoaC CMS1_k127_1849308_0 1122137.AQXF01000003_gene1870 1.355e-214 689.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria 28211|Alphaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran CMS1_k127_1852942_3 1500301.JQMF01000006_gene1689 1.301e-06 50.0 COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,2TQRI@28211|Alphaproteobacteria,4BA4I@82115|Rhizobiaceae 28211|Alphaproteobacteria H molybdopterin moeA GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0042802,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.10.1.1 ko:K03750 ko00790,ko01100,map00790,map01100 - R09735 RC03462 ko00000,ko00001,ko01000 - - - MoCF_biosynth,MoeA_C,MoeA_N CMS1_k127_1852942_2 1187851.A33M_2295 4.604e-119 387.0 COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,2TT7W@28211|Alphaproteobacteria,3FCYT@34008|Rhodovulum 28211|Alphaproteobacteria K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair lexA GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 ko:K01356 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - LexA_DNA_bind,Peptidase_S24 CMS1_k127_1852942_0 1187851.A33M_2296 3.954e-239 762.0 COG0658@1|root,COG0658@2|Bacteria,1MUKF@1224|Proteobacteria,2TRD5@28211|Alphaproteobacteria,3FD4W@34008|Rhodovulum 28211|Alphaproteobacteria S Domain of unknown function (DUF4131) - - - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131 CMS1_k127_1852942_1 1038859.AXAU01000001_gene3023 1.568e-185 584.0 COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,2TRKX@28211|Alphaproteobacteria,3JUGQ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J glutaminyl-tRNA synthetase glnS - 6.1.1.18 ko:K01886 ko00970,ko01100,map00970,map01100 M00359,M00360 R03652 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1c,tRNA-synt_1c_C CMS1_k127_1858692_1 1187851.A33M_2516 4.282e-110 361.0 COG0329@1|root,COG0329@2|Bacteria,1MXM5@1224|Proteobacteria,2TUAG@28211|Alphaproteobacteria 28211|Alphaproteobacteria EM Belongs to the DapA family - - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS CMS1_k127_1858692_2 114615.BRADO3920 1.533e-06 53.0 COG4953@1|root,COG4953@2|Bacteria,1MUA9@1224|Proteobacteria,2TR2R@28211|Alphaproteobacteria,3JS2X@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Penicillin-Binding Protein C-terminus Family pbpC - 2.4.1.129 ko:K05367 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - BiPBP_C,Transgly,Transpeptidase CMS1_k127_1858692_0 1502851.FG93_02720 7.119e-315 972.0 COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,2TQJT@28211|Alphaproteobacteria,3K2TK@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Malic enzyme, NAD binding domain tme - 1.1.1.40 ko:K00029 ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200 M00169,M00172 R00216 RC00105 ko00000,ko00001,ko00002,ko01000 - - - Malic_M,PTA_PTB,malic CMS1_k127_1864470_4 1380394.JADL01000014_gene137 3.189e-56 208.0 COG2230@1|root,COG2230@2|Bacteria,1QXKQ@1224|Proteobacteria,2TXBW@28211|Alphaproteobacteria,2JYX5@204441|Rhodospirillales 204441|Rhodospirillales M Methyltransferase domain - - - - - - - - - - - - Methyltransf_25 CMS1_k127_1864470_2 1187851.A33M_1786 2.93e-101 337.0 COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,2TR5Z@28211|Alphaproteobacteria,3FCY1@34008|Rhodovulum 28211|Alphaproteobacteria S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis MA20_24865 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 - ko:K06997 - - - - ko00000 - - - Ala_racemase_N CMS1_k127_1864470_3 1500257.JQNM01000002_gene4731 1.632e-84 290.0 COG0664@1|root,COG0664@2|Bacteria,1PIN3@1224|Proteobacteria,2TSFE@28211|Alphaproteobacteria,4BAV9@82115|Rhizobiaceae 28211|Alphaproteobacteria K cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases fixK - - - - - - - - - - - HTH_Crp_2,cNMP_binding CMS1_k127_1864470_5 426355.Mrad2831_2089 8.516e-18 89.0 COG0784@1|root,COG0784@2|Bacteria,1N70P@1224|Proteobacteria,2UF5P@28211|Alphaproteobacteria,1JUPA@119045|Methylobacteriaceae 28211|Alphaproteobacteria T cheY-homologous receiver domain - - - - - - - - - - - - Response_reg CMS1_k127_1864470_1 1123229.AUBC01000003_gene2190 3.992e-137 447.0 COG0845@1|root,COG0845@2|Bacteria,1Q10W@1224|Proteobacteria,2TSC8@28211|Alphaproteobacteria,3JT5F@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Evidence Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - ko:K02005 - - - - ko00000 - - - HlyD_3 CMS1_k127_1864470_0 1123229.AUBC01000003_gene2191 3.652e-290 904.0 COG0577@1|root,COG0577@2|Bacteria,1MW6D@1224|Proteobacteria,2TTJZ@28211|Alphaproteobacteria,3JVPM@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS1_k127_1864612_4 1230476.C207_06963 1.203e-82 276.0 COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,2U25Z@28211|Alphaproteobacteria,3JTBZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Biotin carboxylase accC GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 CMS1_k127_1864612_6 1197906.CAJQ02000011_gene902 3.213e-52 188.0 COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,2U93Y@28211|Alphaproteobacteria,3JY4E@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA accB GO:0003674,GO:0003824,GO:0003989,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009305,GO:0009987,GO:0016049,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576 - ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742 RC00040,RC00367 ko00000,ko00001,ko00002 - - - Biotin_lipoyl CMS1_k127_1864612_5 1187851.A33M_1367 1.432e-55 199.0 COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,2U9BV@28211|Alphaproteobacteria,3FD7K@34008|Rhodovulum 28211|Alphaproteobacteria E Catalyzes a trans-dehydration via an enolate intermediate aroQ - 4.2.1.10 ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03084 RC00848 ko00000,ko00001,ko00002,ko01000 - - - DHquinase_II CMS1_k127_1864612_2 639283.Snov_0344 3.685e-113 376.0 COG2170@1|root,COG2170@2|Bacteria,1MX4N@1224|Proteobacteria,2TR20@28211|Alphaproteobacteria,3EYNI@335928|Xanthobacteraceae 28211|Alphaproteobacteria H ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity - - - ko:K06048 - - - - ko00000,ko01000 - - - GCS2 CMS1_k127_1864612_3 1298867.AUES01000002_gene1340 2.474e-99 334.0 COG1651@1|root,COG1651@2|Bacteria,1MY3H@1224|Proteobacteria,2TTXR@28211|Alphaproteobacteria,3JSBQ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O Thioredoxin MA20_29175 - - - - - - - - - - - DSBA,Thioredoxin_4 CMS1_k127_1864612_1 1297865.APJD01000001_gene5985 4.73e-177 566.0 COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,2TTV2@28211|Alphaproteobacteria,3JSBC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Peptidase family M48 MA20_29180 - - - - - - - - - - - Peptidase_M48,TPR_16,TPR_19 CMS1_k127_1864612_0 316057.RPD_2440 5.936e-181 575.0 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2TS06@28211|Alphaproteobacteria,3JRRH@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Aminotransferase class I and II aspB - - - - - - - - - - - Aminotran_1_2 CMS1_k127_1864612_7 267608.RSc0238 8.634e-07 55.0 COG3619@1|root,COG3619@2|Bacteria,1R5V0@1224|Proteobacteria,2VRY4@28216|Betaproteobacteria,1K4XG@119060|Burkholderiaceae 28216|Betaproteobacteria S Protein of unknown function (DUF1275) - - - - - - - - - - - - DUF1275 CMS1_k127_1887079_8 438753.AZC_0997 2.168e-52 186.0 COG0604@1|root,COG0604@2|Bacteria,1MXIK@1224|Proteobacteria,2TQPR@28211|Alphaproteobacteria,3F088@335928|Xanthobacteraceae 28211|Alphaproteobacteria C Alcohol dehydrogenase GroES-like domain ccrA - 1.1.1.1,1.3.1.85 ko:K00001,ko:K14446 ko00010,ko00071,ko00350,ko00625,ko00626,ko00630,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00010,map00071,map00350,map00625,map00626,map00630,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220 M00373 R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310,R09291 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273,RC02481 ko00000,ko00001,ko00002,ko01000 - - - ADH_N,ADH_zinc_N CMS1_k127_1887079_2 1038859.AXAU01000012_gene4329 6.694e-110 368.0 2CIPC@1|root,2Z9HB@2|Bacteria,1R3W8@1224|Proteobacteria,2TST7@28211|Alphaproteobacteria,3JTHB@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Glycosyltransferase family 87 - - - - - - - - - - - - GT87 CMS1_k127_1887079_0 438753.AZC_0992 0.0 1015.0 COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,2TQYC@28211|Alphaproteobacteria,3F14A@335928|Xanthobacteraceae 28211|Alphaproteobacteria I B12 binding domain mutB - 5.4.99.63 ko:K14447 ko00630,ko01120,ko01200,map00630,map01120,map01200 M00373 R09292 RC02835 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,MM_CoA_mutase CMS1_k127_1887079_3 1040989.AWZU01000001_gene5540 5.701e-108 365.0 COG0642@1|root,COG0784@1|root,COG0642@2|Bacteria,COG0784@2|Bacteria,1NC9X@1224|Proteobacteria,2TWQ8@28211|Alphaproteobacteria,3K6KY@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,Response_reg CMS1_k127_1887079_1 443598.AUFA01000009_gene5843 2.701e-137 441.0 COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,2TR2V@28211|Alphaproteobacteria,3JUNB@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Belongs to the class-I aminoacyl-tRNA synthetase family gluQ - - ko:K01894 - - - - ko00000,ko01000,ko01007,ko03016 - - - tRNA-synt_1c CMS1_k127_1887079_6 258594.RPA4755 1.195e-78 270.0 COG0122@1|root,COG0122@2|Bacteria,1MX9C@1224|Proteobacteria,2TVJ7@28211|Alphaproteobacteria,3JU5E@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L endonuclease III alkA - 3.2.2.21 ko:K01247 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - HhH-GPD CMS1_k127_1887079_5 1211115.ALIQ01000145_gene1003 8.909e-100 331.0 COG0400@1|root,COG0400@2|Bacteria,1RA02@1224|Proteobacteria,2TTWP@28211|Alphaproteobacteria,3NA1J@45404|Beijerinckiaceae 28211|Alphaproteobacteria S Phospholipase/Carboxylesterase - - - ko:K06999 - - - - ko00000 - - - Abhydrolase_2 CMS1_k127_1887079_4 1429916.X566_05405 5.561e-107 348.0 COG1403@1|root,COG1403@2|Bacteria,1MWEQ@1224|Proteobacteria,2TR3M@28211|Alphaproteobacteria,3JS4T@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L HNH endonuclease MA20_20605 - - - - - - - - - - - HNH,HNH_5 CMS1_k127_1887079_7 1297863.APJF01000010_gene3395 2.1e-54 196.0 COG1495@1|root,COG1495@2|Bacteria,1N89I@1224|Proteobacteria,2UF49@28211|Alphaproteobacteria,3JUXI@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O Disulfide bond formation protein DsbB dsbB - - ko:K03611 - - - - ko00000,ko03110 5.A.2.1 - - DsbB CMS1_k127_1887079_9 1297863.APJF01000022_gene4610 3.736e-23 102.0 2E7PS@1|root,3325B@2|Bacteria,1N7R7@1224|Proteobacteria,2UFCM@28211|Alphaproteobacteria,3K0ZR@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Evidence 4 Homologs of previously reported genes of - - - - - - - - - - - - - CMS1_k127_1887079_10 936455.KI421499_gene1371 1.68e-09 59.0 COG4091@1|root,COG4091@2|Bacteria,1MUZX@1224|Proteobacteria,2TRZ0@28211|Alphaproteobacteria,3JU4R@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E homoserine dehydrogenase - - 1.1.1.3 ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00017,M00018 R01773,R01775 RC00087 ko00000,ko00001,ko00002,ko01000 - - - GFO_IDH_MocA,NAD_binding_3,SAF CMS1_k127_1890093_1 1123229.AUBC01000013_gene2572 8.379e-36 137.0 COG3536@1|root,COG3536@2|Bacteria,1MZ5M@1224|Proteobacteria,2U9GJ@28211|Alphaproteobacteria,3JZ74@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF971) - - - - - - - - - - - - DUF971 CMS1_k127_1890093_0 1231391.AMZF01000001_gene2886 1.396e-119 402.0 COG0654@1|root,COG0654@2|Bacteria,1MUN4@1224|Proteobacteria,2VN4I@28216|Betaproteobacteria,3T6WQ@506|Alcaligenaceae 28216|Betaproteobacteria CH FAD binding domain - - - - - - - - - - - - FAD_binding_3 CMS1_k127_1892658_0 1429916.X566_09110 9.322e-97 317.0 COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,2TRB4@28211|Alphaproteobacteria,3JQY5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template rho - - ko:K03628 ko03018,map03018 - - - ko00000,ko00001,ko03019,ko03021 - - - ATP-synt_ab,Rho_N,Rho_RNA_bind CMS1_k127_1892658_1 1245469.S58_67480 6.904e-25 113.0 2A7V7@1|root,30WUE@2|Bacteria,1REVV@1224|Proteobacteria,2U8RW@28211|Alphaproteobacteria,3JZ5W@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_1916851_4 1380355.JNIJ01000009_gene1790 2.105e-42 157.0 COG0604@1|root,COG0604@2|Bacteria,1MUTW@1224|Proteobacteria,2U1CB@28211|Alphaproteobacteria,3JU0H@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Zinc-binding dehydrogenase adh - 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N CMS1_k127_1916851_0 323097.Nham_1503 8.278e-197 622.0 COG0304@1|root,COG0304@2|Bacteria,1PVH9@1224|Proteobacteria,2TSMB@28211|Alphaproteobacteria,3JR29@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria IQ Belongs to the beta-ketoacyl-ACP synthases family fabF3 - 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt CMS1_k127_1916851_1 1187851.A33M_2132 1.123e-168 539.0 COG0304@1|root,COG0304@2|Bacteria,1MXZ7@1224|Proteobacteria,2TVEB@28211|Alphaproteobacteria 28211|Alphaproteobacteria IQ synthase fabF2 - 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ketoacyl-synt CMS1_k127_1916851_2 316058.RPB_3354 3.276e-57 203.0 COG0764@1|root,COG0764@2|Bacteria,1RJND@1224|Proteobacteria,2UA4J@28211|Alphaproteobacteria,3JYDB@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I FabA-like domain - - 4.2.1.59 ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121 RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FabA CMS1_k127_1916851_3 316055.RPE_2023 2.203e-47 173.0 COG0236@1|root,COG0236@2|Bacteria,1RI81@1224|Proteobacteria,2U9I5@28211|Alphaproteobacteria,3JZEG@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria IQ Phosphopantetheine attachment site acpXL GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - - - - - - - - - - PP-binding CMS1_k127_1916851_5 1038867.AXAY01000011_gene5324 5.387e-17 84.0 2A87P@1|root,30X8R@2|Bacteria,1RFTN@1224|Proteobacteria,2U7BA@28211|Alphaproteobacteria,3JYXG@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_192_1 1187851.A33M_3947 6.84e-118 398.0 COG0389@1|root,COG0389@2|Bacteria,1MU5X@1224|Proteobacteria,2TQVR@28211|Alphaproteobacteria,3FD85@34008|Rhodovulum 28211|Alphaproteobacteria L Nucleotidyltransferase DNA polymerase involved in DNA repair imuB - - ko:K14161 - - - - ko00000,ko03400 - - - IMS CMS1_k127_192_2 1187851.A33M_3946 1.824e-36 148.0 COG4544@1|root,COG4544@2|Bacteria,1MY56@1224|Proteobacteria,2TT91@28211|Alphaproteobacteria 28211|Alphaproteobacteria S SOS response - - - ko:K14160 - - - - ko00000,ko03400 - - - - CMS1_k127_192_0 1187851.A33M_3633 4.677e-130 434.0 COG0845@1|root,COG0845@2|Bacteria,1MXU4@1224|Proteobacteria,2TUXB@28211|Alphaproteobacteria,3FD1B@34008|Rhodovulum 28211|Alphaproteobacteria M HlyD family secretion protein - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 CMS1_k127_192_3 316056.RPC_3221 1.911e-35 136.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria,3JURY@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran CMS1_k127_1920089_7 371731.Rsw2DRAFT_3303 1.119e-61 215.0 COG0509@1|root,COG0509@2|Bacteria,1RKRS@1224|Proteobacteria,2UAPN@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Glycine cleavage H-protein - - - ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 - - - GCV_H CMS1_k127_1920089_6 1417296.U879_08110 2.575e-73 250.0 COG2210@1|root,COG2210@2|Bacteria,1RDUG@1224|Proteobacteria,2U6FZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S DsrE/DsrF/DrsH-like family - - - - - - - - - - - - DrsE_2 CMS1_k127_1920089_8 1417296.U879_08115 1.501e-31 124.0 COG0425@1|root,COG0425@2|Bacteria,1MZA5@1224|Proteobacteria 1224|Proteobacteria O Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin - - - ko:K04085 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - TusA CMS1_k127_1920089_1 1430440.MGMSRv2_3818 1.563e-128 420.0 COG2391@1|root,COG2391@2|Bacteria,1MXSE@1224|Proteobacteria,2TRUQ@28211|Alphaproteobacteria,2JSW4@204441|Rhodospirillales 204441|Rhodospirillales S Sulphur transport - - - ko:K07112 - - - - ko00000 - - - Sulf_transp CMS1_k127_1920089_2 1192868.CAIU01000013_gene1762 8.771e-123 404.0 COG2855@1|root,COG2855@2|Bacteria,1MVIP@1224|Proteobacteria,2TVK9@28211|Alphaproteobacteria,43HQF@69277|Phyllobacteriaceae 28211|Alphaproteobacteria C membrane yeiH - - - - - - - - - - - Cons_hypoth698 CMS1_k127_1920089_3 876269.ARWA01000001_gene1382 1.171e-120 394.0 COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,2TQS4@28211|Alphaproteobacteria,3NA37@45404|Beijerinckiaceae 28211|Alphaproteobacteria K PBP superfamily domain yeiE - - - - - - - - - - - HTH_1,LysR_substrate CMS1_k127_1920089_4 1255043.TVNIR_3613 1.626e-109 361.0 2BX2I@1|root,2Z9KR@2|Bacteria,1MXKC@1224|Proteobacteria,1RRV2@1236|Gammaproteobacteria,1WXVA@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - CMS1_k127_1920089_5 713587.THITH_01410 7.032e-95 311.0 COG1146@1|root,COG1146@2|Bacteria,1R4GP@1224|Proteobacteria,1RXXW@1236|Gammaproteobacteria,1WVWW@135613|Chromatiales 135613|Chromatiales C reductase beta subunit - - 1.8.99.2 ko:K00395 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00596 R00860,R04927,R08553 RC00007,RC01239,RC02862 ko00000,ko00001,ko00002,ko01000 - - - APS-reductase_C,Fer4,Fer4_9 CMS1_k127_1920089_0 765912.Thimo_1219 0.0 1204.0 COG1053@1|root,COG1053@2|Bacteria,1NZBR@1224|Proteobacteria,1RZ0U@1236|Gammaproteobacteria,1WW7B@135613|Chromatiales 135613|Chromatiales C reductase, alpha subunit - - 1.8.99.2 ko:K00394 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00596 R00860,R04927,R08553 RC00007,RC01239,RC02862 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C CMS1_k127_1920089_9 1249627.D779_0179 3.338e-14 76.0 2BK43@1|root,32EHP@2|Bacteria,1RDAC@1224|Proteobacteria,1S4CA@1236|Gammaproteobacteria,1WY9U@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - CMS1_k127_1930994_4 1187851.A33M_0591 6.098e-66 231.0 COG1247@1|root,COG1247@2|Bacteria,1N0PB@1224|Proteobacteria,2UC2G@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Acetyltransferase (GNAT) family MA20_28525 - - - - - - - - - - - Acetyltransf_1 CMS1_k127_1930994_2 1126627.BAWE01000002_gene942 3.157e-78 264.0 COG1514@1|root,COG1514@2|Bacteria,1RDB2@1224|Proteobacteria,2U7FV@28211|Alphaproteobacteria,3JTFI@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester ligT - 3.1.4.58 ko:K01975 - - - - ko00000,ko01000,ko03016 - - - LigT_PEase CMS1_k127_1930994_3 1411123.JQNH01000001_gene2645 4.028e-72 250.0 COG2755@1|root,COG2755@2|Bacteria,1RCXZ@1224|Proteobacteria,2U74E@28211|Alphaproteobacteria 28211|Alphaproteobacteria E COG2755 Lysophospholipase L1 and related esterases tesA - 3.1.1.5 ko:K10804 ko01040,map01040 - - - ko00000,ko00001,ko01000,ko01004 - - - Lipase_GDSL_2 CMS1_k127_1930994_1 316056.RPC_0198 6.286e-101 334.0 COG4181@1|root,COG4181@2|Bacteria,1MXG9@1224|Proteobacteria,2TS0J@28211|Alphaproteobacteria,3JS8X@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria Q ABC transporter ybbA GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran CMS1_k127_1930994_0 1380355.JNIJ01000014_gene481 0.0 1061.0 COG3127@1|root,COG3127@2|Bacteria,1MU9R@1224|Proteobacteria,2TS8V@28211|Alphaproteobacteria,3JUPK@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria Q FtsX-like permease family MA20_43810 - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS1_k127_1933923_3 1187851.A33M_4202 2.299e-64 234.0 COG1232@1|root,COG1232@2|Bacteria,1NQUH@1224|Proteobacteria,2TTH7@28211|Alphaproteobacteria 28211|Alphaproteobacteria H PFAM amine oxidase hpnE - 1.17.8.1 ko:K21677 - - - - ko00000,ko01000 - - - Amino_oxidase CMS1_k127_1933923_2 1040989.AWZU01000012_gene1357 4.457e-98 329.0 COG1562@1|root,COG1562@2|Bacteria,1MX4W@1224|Proteobacteria,2TTI0@28211|Alphaproteobacteria,3JUXY@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Squalene/phytoene synthase hpnD - 2.5.1.103,2.5.1.32,2.5.1.99 ko:K02291,ko:K21678 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 M00097 R02065,R04218,R07270,R10177 RC00362,RC01101,RC02869 ko00000,ko00001,ko00002,ko01000,ko01006 - - - SQS_PSY CMS1_k127_1933923_1 172088.AUGA01000024_gene874 1.115e-100 343.0 COG1562@1|root,COG1562@2|Bacteria,1N6J2@1224|Proteobacteria,2TT8U@28211|Alphaproteobacteria,3JQW6@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Squalene/phytoene synthase hpnC - 2.5.1.103,4.2.3.156 ko:K21678,ko:K21679 - - - - ko00000,ko01000 - - - SQS_PSY CMS1_k127_1933923_0 1054213.HMPREF9946_02995 2.407e-129 428.0 COG1215@1|root,COG1215@2|Bacteria,1MW1E@1224|Proteobacteria,2U30S@28211|Alphaproteobacteria,2JR6T@204441|Rhodospirillales 204441|Rhodospirillales M Glycosyl transferase family 21 - - - - - - - - - - - - Glyco_tranf_2_3,Glycos_transf_2,SQS_PSY CMS1_k127_1933923_4 1101192.KB910516_gene1738 9.991e-44 166.0 COG1215@1|root,COG1215@2|Bacteria,1Q6U2@1224|Proteobacteria,2VG3U@28211|Alphaproteobacteria,1JR0E@119045|Methylobacteriaceae 28211|Alphaproteobacteria M TIGRFAM hopanoid biosynthesis associated glycosyl transferase protein HpnI - - 2.4.1.80 ko:K00720 ko00600,ko01100,map00600,map01100 M00066 R01497 RC00005,RC00059 ko00000,ko00001,ko00002,ko01000,ko01003,ko02000 4.D.1.4 GT21 - Glyco_transf_21 CMS1_k127_1934997_11 1205680.CAKO01000007_gene4442 3.02e-50 183.0 COG0848@1|root,COG0848@2|Bacteria,1RDJZ@1224|Proteobacteria,2U77T@28211|Alphaproteobacteria,2JT2S@204441|Rhodospirillales 204441|Rhodospirillales U Biopolymer transport protein exbD - - ko:K03559 - - - - ko00000,ko02000 1.A.30.2.1 - - ExbD CMS1_k127_1934997_6 935548.KI912159_gene3526 3.404e-81 280.0 COG0811@1|root,COG0811@2|Bacteria,1MXHR@1224|Proteobacteria,2TQNN@28211|Alphaproteobacteria,43GRG@69277|Phyllobacteriaceae 28211|Alphaproteobacteria U tonB-system energizer ExbB exbB - - ko:K03561 - - - - ko00000,ko02000 1.A.30.2.1 - - MotA_ExbB CMS1_k127_1934997_4 1380394.JADL01000008_gene3571 2.255e-94 322.0 COG0715@1|root,COG0715@2|Bacteria,1NUSF@1224|Proteobacteria,2TTKK@28211|Alphaproteobacteria 28211|Alphaproteobacteria P ABC transporter, phosphonate, periplasmic substrate-binding protein MA20_38205 - - ko:K02051,ko:K15553 ko00920,ko02010,map00920,map02010 M00188,M00436 - - ko00000,ko00001,ko00002,ko02000 3.A.1.16,3.A.1.17,3.A.1.17.2 - - NMT1,NMT1_2 CMS1_k127_1934997_8 639283.Snov_0220 1.845e-73 261.0 COG0600@1|root,COG0600@2|Bacteria,1NSKG@1224|Proteobacteria,2TTPZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Function proposed based on presence of conserved amino acid motif, structural feature or limited homology MA20_38185 - - ko:K02050 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - BPD_transp_1 CMS1_k127_1934997_7 1380394.JADL01000008_gene3563 7.016e-74 272.0 COG0600@1|root,COG0600@2|Bacteria,1QZW9@1224|Proteobacteria,2TVF6@28211|Alphaproteobacteria,2JX2G@204441|Rhodospirillales 204441|Rhodospirillales P Binding-protein-dependent transport system inner membrane component - - - - - - - - - - - - BPD_transp_1 CMS1_k127_1934997_3 1380394.JADL01000008_gene3564 1.092e-114 375.0 COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,2TSH9@28211|Alphaproteobacteria,2JPWP@204441|Rhodospirillales 204441|Rhodospirillales P ATPases associated with a variety of cellular activities - - - ko:K02049 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - ABC_tran CMS1_k127_1934997_9 1502851.FG93_02504 6.16e-68 241.0 COG2084@1|root,COG2084@2|Bacteria,1MX8V@1224|Proteobacteria,2TVBS@28211|Alphaproteobacteria,3JTCY@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Domain of unknown function (DUF1932) MA20_26655 - - - - - - - - - - - DUF1932,F420_oxidored,NAD_binding_2 CMS1_k127_1934997_0 1038859.AXAU01000001_gene3915 1.074e-177 563.0 COG0346@1|root,COG0346@2|Bacteria,1MUWY@1224|Proteobacteria,2TTMJ@28211|Alphaproteobacteria,3JSUU@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily xylE - 1.13.11.2 ko:K00446 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 M00569 R00816,R04089,R05295,R05404,R05406,R07795 RC00387,RC00643,RC01075,RC01364,RC01914 br01602,ko00000,ko00001,ko00002,ko01000 - - - Glyoxalase CMS1_k127_1934997_5 288000.BBta_0698 8.554e-86 289.0 COG0220@1|root,COG0220@2|Bacteria,1QTX5@1224|Proteobacteria,2TWA0@28211|Alphaproteobacteria,3K6SX@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Protein of unknown function (DUF938) - - - - - - - - - - - - DUF938 CMS1_k127_1934997_12 1144342.PMI40_04322 1.178e-18 98.0 COG0715@1|root,COG0715@2|Bacteria,1MWC5@1224|Proteobacteria,2W625@28216|Betaproteobacteria 28216|Betaproteobacteria P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 CMS1_k127_1934997_10 1123023.JIAI01000002_gene4972 3.098e-64 231.0 COG0600@1|root,COG0600@2|Bacteria,2GP2J@201174|Actinobacteria 201174|Actinobacteria P ABC-type nitrate sulfonate bicarbonate transport system, permease component - - - ko:K02050 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - BPD_transp_1 CMS1_k127_1934997_1 443598.AUFA01000058_gene7306 2.421e-156 501.0 COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,2TTWK@28211|Alphaproteobacteria,3K3T8@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Cobalamin-independent synthase, Catalytic domain metE - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_2 CMS1_k127_1934997_13 454957.IA64_08840 1.047e-08 64.0 COG2259@1|root,COG2259@2|Bacteria,1RDYW@1224|Proteobacteria,1S6UK@1236|Gammaproteobacteria,1XARI@135614|Xanthomonadales 135614|Xanthomonadales S DoxX - - - ko:K15977 - - - - ko00000 - - - DoxX CMS1_k127_1934997_2 319003.Bra1253DRAFT_01456 2.079e-117 380.0 COG0684@1|root,COG0684@2|Bacteria,1MW9P@1224|Proteobacteria,2TTGT@28211|Alphaproteobacteria,3JSDX@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H Aldolase/RraA ligK - 4.1.3.17 ko:K02553,ko:K10218 ko00362,ko00660,ko01120,map00362,map00660,map01120 - R00008,R00350 RC00067,RC00502,RC01205 ko00000,ko00001,ko01000,ko03019 - - - RraA-like CMS1_k127_1936427_2 1187851.A33M_2481 1.167e-170 555.0 COG3825@1|root,COG3825@2|Bacteria,1MUAJ@1224|Proteobacteria,2TS5P@28211|Alphaproteobacteria,3FCW3@34008|Rhodovulum 28211|Alphaproteobacteria S Protein conserved in bacteria MA20_01305 - - ko:K09989 - - - - ko00000 - - - VWA_CoxE CMS1_k127_1936427_8 1123060.JONP01000014_gene4161 1.303e-71 258.0 COG0834@1|root,COG0834@2|Bacteria,1N2RR@1224|Proteobacteria,2U0AF@28211|Alphaproteobacteria 28211|Alphaproteobacteria ET COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain - - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 CMS1_k127_1936427_12 1230476.C207_00822 6.939e-36 141.0 COG0824@1|root,COG0824@2|Bacteria,1MZFI@1224|Proteobacteria,2U5Q6@28211|Alphaproteobacteria,3JSEZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Acyl-ACP thioesterase MA20_08165 - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT,4HBT_2,Acyl-ACP_TE CMS1_k127_1936427_1 402881.Plav_3170 1.931e-171 546.0 COG0654@1|root,COG0654@2|Bacteria,1P1NX@1224|Proteobacteria,2TRZX@28211|Alphaproteobacteria,1JPMJ@119043|Rhodobiaceae 28211|Alphaproteobacteria CH FAD binding domain - - - - - - - - - - - - FAD_binding_3 CMS1_k127_1936427_9 1125973.JNLC01000001_gene123 3.835e-53 193.0 COG0633@1|root,COG0633@2|Bacteria,1RHDC@1224|Proteobacteria,2U97J@28211|Alphaproteobacteria,3JYP7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C 2Fe-2S iron-sulfur cluster binding domain fdx - - ko:K04755 - - - - ko00000 - - - Fer2 CMS1_k127_1936427_14 1187851.A33M_2490 7.473e-15 80.0 COG2198@1|root,COG2198@2|Bacteria 2|Bacteria T Histidine kinase - - 2.7.13.3 ko:K07647 ko02020,map02020 M00455 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - Hpt CMS1_k127_1936427_0 666684.AfiDRAFT_0142 3.457e-293 947.0 COG1196@1|root,COG1196@2|Bacteria,1MVEP@1224|Proteobacteria,2TR50@28211|Alphaproteobacteria,3K6UN@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria D Apolipoprotein A1/A4/E domain - - - - - - - - - - - - Apolipoprotein CMS1_k127_1936427_10 1120792.JAFV01000001_gene1273 1.25e-42 166.0 COG3218@1|root,COG3218@2|Bacteria,1RI22@1224|Proteobacteria,2UB1D@28211|Alphaproteobacteria,36YW2@31993|Methylocystaceae 28211|Alphaproteobacteria S ABC-type transport auxiliary lipoprotein component - - - ko:K18480 - M00669 - - ko00000,ko00002,ko02000 3.A.1.27.1 - - ABC_trans_aux CMS1_k127_1936427_7 1429916.X566_01665 4.105e-74 259.0 COG1463@1|root,COG1463@2|Bacteria,1MU4B@1224|Proteobacteria,2U1JN@28211|Alphaproteobacteria,3JU5J@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria Q MlaD protein MA20_08125 - - ko:K02067 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaD CMS1_k127_1936427_5 1038858.AXBA01000001_gene3221 5.815e-115 376.0 COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,2TR2I@28211|Alphaproteobacteria,3EXUZ@335928|Xanthobacteraceae 28211|Alphaproteobacteria Q ATPases associated with a variety of cellular activities yrbF - - ko:K02065 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - ABC_tran CMS1_k127_1936427_3 1187851.A33M_1134 1.085e-140 457.0 COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,2TSGS@28211|Alphaproteobacteria,3FDC7@34008|Rhodovulum 28211|Alphaproteobacteria Q Permease MlaE - - - ko:K02066 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaE,STAS,STAS_2 CMS1_k127_1936427_4 1297865.APJD01000047_gene4782 1.73e-127 415.0 COG4948@1|root,COG4948@2|Bacteria,1MW76@1224|Proteobacteria,2TR16@28211|Alphaproteobacteria,3JUPA@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M mandelate racemase muconate lactonizing ycjG GO:0003674,GO:0003824,GO:0016853,GO:0016854,GO:0016855 5.1.1.20 ko:K19802 - - R10938 RC03309 ko00000,ko01000 - - - MR_MLE_C,MR_MLE_N CMS1_k127_1936427_11 652103.Rpdx1_4865 3.956e-40 155.0 2EHAM@1|root,33B2H@2|Bacteria,1MY41@1224|Proteobacteria,2U1A7@28211|Alphaproteobacteria,3JRY4@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - MA20_22125 - - - - - - - - - - - - CMS1_k127_1936427_6 316056.RPC_1450 4.514e-88 304.0 COG0477@1|root,COG2814@2|Bacteria,1MVZI@1224|Proteobacteria,2U5H1@28211|Alphaproteobacteria,3JSND@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria EGP Nucleoside H+ symporter - - - ko:K05820 - - - - ko00000,ko02000 2.A.1.27 - - MFS_1_like CMS1_k127_1936427_15 1411123.JQNH01000001_gene1919 4.516e-08 64.0 COG3143@1|root,COG3143@2|Bacteria,1MX6Z@1224|Proteobacteria,2TVRM@28211|Alphaproteobacteria 28211|Alphaproteobacteria NT Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) - - - - - - - - - - - - CheZ CMS1_k127_1936427_13 1298867.AUES01000043_gene3642 4.265e-24 102.0 COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2TQN9@28211|Alphaproteobacteria,3JQZ0@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Pyridoxal-phosphate dependent enzyme tdcB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006520,GO:0006563,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016841,GO:0016853,GO:0016854,GO:0016855,GO:0017144,GO:0018249,GO:0019538,GO:0019752,GO:0019842,GO:0030170,GO:0030378,GO:0030848,GO:0036094,GO:0036211,GO:0036361,GO:0042219,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046416,GO:0046437,GO:0046872,GO:0047661,GO:0048037,GO:0050662,GO:0070178,GO:0070179,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901607 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP CMS1_k127_194060_3 323097.Nham_0679 3.01e-43 159.0 COG3409@1|root,COG3409@2|Bacteria,1R4RS@1224|Proteobacteria,2U0FF@28211|Alphaproteobacteria,3JYB3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M CHAP domain - - - - - - - - - - - - CHAP CMS1_k127_194060_2 316055.RPE_4338 1.566e-43 169.0 COG3409@1|root,COG3409@2|Bacteria,1R4RS@1224|Proteobacteria,2U0FF@28211|Alphaproteobacteria,3JYB3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M CHAP domain - - - - - - - - - - - - CHAP CMS1_k127_194060_1 709797.CSIRO_1597 2.455e-108 356.0 COG3217@1|root,COG3217@2|Bacteria,1MVSP@1224|Proteobacteria,2U1ST@28211|Alphaproteobacteria,3JSY4@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S MOSC N-terminal beta barrel domain - - - ko:K07140 - - - - ko00000 - - - MOSC,MOSC_N CMS1_k127_194060_0 1429916.X566_05120 0.0 1008.0 COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,2TRKI@28211|Alphaproteobacteria,3JRD0@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpB - - ko:K03695 ko04213,map04213 - - - ko00000,ko00001,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N CMS1_k127_1958828_5 1187851.A33M_0462 1.247e-118 390.0 COG1451@1|root,COG1451@2|Bacteria,1MXZU@1224|Proteobacteria,2U1JG@28211|Alphaproteobacteria,3FDB6@34008|Rhodovulum 28211|Alphaproteobacteria S Protein of unknown function DUF45 MA20_23375 - - ko:K07043 - - - - ko00000 - - - DUF45 CMS1_k127_1958828_6 1187851.A33M_3471 1.677e-115 384.0 COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,2TRQD@28211|Alphaproteobacteria,3FDSD@34008|Rhodovulum 28211|Alphaproteobacteria EGP Major Facilitator Superfamily - - - ko:K07552 - - - - ko00000,ko02000 2.A.1.2 - - MFS_1 CMS1_k127_1958828_10 1294273.roselon_00351 5.437e-06 53.0 COG3703@1|root,COG3703@2|Bacteria,1QA7D@1224|Proteobacteria,2U84Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides - - - ko:K07232 - - - - ko00000 - - - ChaC CMS1_k127_1958828_7 1380355.JNIJ01000025_gene1187 5.517e-70 248.0 COG0500@1|root,COG2226@2|Bacteria,1PPKI@1224|Proteobacteria,2TRIB@28211|Alphaproteobacteria,3JRP5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria Q ubiE/COQ5 methyltransferase family MA20_37085 - - - - - - - - - - - Methyltransf_11,Methyltransf_25 CMS1_k127_1958828_9 172088.AUGA01000057_gene3455 1.354e-07 54.0 COG3293@1|root,COG3293@2|Bacteria,1P5HD@1224|Proteobacteria,2TUQI@28211|Alphaproteobacteria,3JZFP@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L Transposase DDE domain - - - - - - - - - - - - DDE_Tnp_1_2,DUF4096 CMS1_k127_1958828_0 323097.Nham_0227 1.969e-276 865.0 COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,2TQQ8@28211|Alphaproteobacteria,3JR5K@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Penicillin-binding Protein pbpC - 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase CMS1_k127_1958828_3 1245469.S58_03430 1.209e-178 603.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria,3JRAF@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL,GGDEF,PAS_3,PAS_4,PAS_7,PAS_8,dCache_1 CMS1_k127_1958828_2 639283.Snov_1187 1.74e-263 819.0 COG0213@1|root,COG0213@2|Bacteria 2|Bacteria F phosphorylase activity pdp GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.2,2.4.2.4 ko:K00756,ko:K00758 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 - R01570,R01876,R02296,R02484,R08222,R08230 RC00063 ko00000,ko00001,ko01000 - - iHN637.CLJU_RS08925 Glycos_trans_3N,Glycos_transf_3,PYNP_C CMS1_k127_1958828_4 335659.S23_48880 4.594e-119 393.0 COG0462@1|root,COG0462@2|Bacteria,1MUV7@1224|Proteobacteria,2U3AB@28211|Alphaproteobacteria,3JVN2@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria F N-terminal domain of ribose phosphate pyrophosphokinase - - 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyltran,Pribosyltran_N CMS1_k127_1958828_1 398525.KB900701_gene766 1.097e-271 843.0 COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,2TVFM@28211|Alphaproteobacteria,3JU89@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Beta-Casp domain - - - ko:K07576 - - - - ko00000 - - - Beta-Casp,Lactamase_B,Lactamase_B_2,RMMBL CMS1_k127_1958828_8 316056.RPC_0342 3.204e-35 135.0 COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,2TSV0@28211|Alphaproteobacteria,3JV2M@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen glnD GO:0006355,GO:0006464,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008150,GO:0008152,GO:0009605,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0018175,GO:0018177,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:1901564,GO:1901698,GO:1901699,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 2.7.7.59 ko:K00990 ko02020,map02020 - - - ko00000,ko00001,ko01000 - - - ACT,GlnD_UR_UTase,GlnE,HD,NTP_transf_2 CMS1_k127_1968519_26 1205680.CAKO01000038_gene1586 3.649e-20 96.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2TQWK@28211|Alphaproteobacteria,2JRXA@204441|Rhodospirillales 204441|Rhodospirillales S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC CMS1_k127_1968519_2 1089551.KE386572_gene3222 2.865e-147 469.0 COG1878@1|root,COG1878@2|Bacteria,1MV8S@1224|Proteobacteria,2TSUJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S PFAM cyclase family protein - - - - - - - - - - - - Cyclase CMS1_k127_1968519_24 1187851.A33M_2600 3.837e-43 174.0 COG5470@1|root,COG5470@2|Bacteria,1NHS6@1224|Proteobacteria,2UMFK@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Domain of unknown function (DUF1330) - - - - - - - - - - - - DUF1330 CMS1_k127_1968519_1 1380394.JADL01000004_gene5935 1.092e-149 488.0 COG0683@1|root,COG0683@2|Bacteria,1NHBN@1224|Proteobacteria,2TWTC@28211|Alphaproteobacteria,2JR5U@204441|Rhodospirillales 204441|Rhodospirillales E Periplasmic binding protein domain - - - - - - - - - - - - Peripla_BP_6 CMS1_k127_1968519_8 1187851.A33M_2606 2.18e-113 372.0 COG0559@1|root,COG0559@2|Bacteria,1R5JM@1224|Proteobacteria,2TUSY@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Branched-chain amino acid transport system / permease component - - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 CMS1_k127_1968519_9 1380394.JADL01000004_gene5933 1.488e-102 342.0 COG4177@1|root,COG4177@2|Bacteria,1PSHZ@1224|Proteobacteria,2TVQQ@28211|Alphaproteobacteria,2JVEV@204441|Rhodospirillales 204441|Rhodospirillales E Branched-chain amino acid transport system / permease component - - - - - - - - - - - - BPD_transp_2 CMS1_k127_1968519_22 698757.Pogu_1364 1.21e-46 177.0 COG0411@1|root,arCOG00925@2157|Archaea 698757.Pogu_1364|- E COG0411 ABC-type branched-chain amino acid transport systems ATPase component - - - ko:K01995 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - - CMS1_k127_1968519_11 1187851.A33M_2603 9.651e-98 325.0 COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2TR61@28211|Alphaproteobacteria,3FD1Y@34008|Rhodovulum 28211|Alphaproteobacteria E ATPases associated with a variety of cellular activities - - - ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C CMS1_k127_1968519_23 1187851.A33M_2607 7.834e-45 168.0 COG1917@1|root,COG1917@2|Bacteria,1RH1R@1224|Proteobacteria,2UBCW@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Cupin 2, conserved barrel domain protein - - - - - - - - - - - - - CMS1_k127_1968519_6 460265.Mnod_3158 2.202e-117 390.0 COG0654@1|root,COG0654@2|Bacteria,1QXV0@1224|Proteobacteria,2TWCX@28211|Alphaproteobacteria,1JU7N@119045|Methylobacteriaceae 28211|Alphaproteobacteria C PFAM monooxygenase FAD-binding - - - - - - - - - - - - FAD_binding_3 CMS1_k127_1968519_5 639283.Snov_0217 2.056e-127 418.0 COG2159@1|root,COG2159@2|Bacteria,1R5PG@1224|Proteobacteria,2U2G9@28211|Alphaproteobacteria,3F1EG@335928|Xanthobacteraceae 28211|Alphaproteobacteria S Amidohydrolase - - 4.1.1.45 ko:K03392 ko00380,ko01100,map00380,map01100 M00038 R04323 RC00779 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_2 CMS1_k127_1968519_3 1207063.P24_07784 2.286e-133 430.0 COG2175@1|root,COG2175@2|Bacteria,1MV5K@1224|Proteobacteria,2TQTZ@28211|Alphaproteobacteria,2JSGW@204441|Rhodospirillales 204441|Rhodospirillales Q Taurine catabolism dioxygenase TauD, TfdA family tauD - 1.14.11.17 ko:K03119,ko:K22303 ko00430,ko00920,map00430,map00920 - R05320 RC01331 ko00000,ko00001,ko01000 - - - TauD CMS1_k127_1968519_4 258594.RPA3963 2.521e-132 432.0 COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,2TSGS@28211|Alphaproteobacteria,3JTST@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria Q Permease MlaE MA20_08115 - - ko:K02066 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaE,STAS,STAS_2 CMS1_k127_1968519_7 258594.RPA3962 3.11e-115 376.0 COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,2TR2I@28211|Alphaproteobacteria,3JRZD@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria Q ABC transporter yrbF - - ko:K02065 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - ABC_tran CMS1_k127_1968519_20 1429916.X566_01665 7.407e-65 231.0 COG1463@1|root,COG1463@2|Bacteria,1MU4B@1224|Proteobacteria,2U1JN@28211|Alphaproteobacteria,3JU5J@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria Q MlaD protein MA20_08125 - - ko:K02067 ko02010,map02010 M00210,M00669,M00670 - - ko00000,ko00001,ko00002,ko02000 3.A.1.27 - - MlaD CMS1_k127_1968519_14 1118054.CAGW01000061_gene2426 7.13e-81 275.0 COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,4HABJ@91061|Bacilli,26RRC@186822|Paenibacillaceae 91061|Bacilli E ABC transporter - - - - - - - - - - - - ABC_tran CMS1_k127_1968519_16 706587.Desti_0846 2.477e-73 256.0 COG0411@1|root,COG0411@2|Bacteria,1MX51@1224|Proteobacteria,42S2H@68525|delta/epsilon subdivisions,2WNMT@28221|Deltaproteobacteria 28221|Deltaproteobacteria E Branched-chain amino acid ATP-binding cassette transporter - - - ko:K01995 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C CMS1_k127_1968519_13 666684.AfiDRAFT_2647 9.274e-85 297.0 COG0683@1|root,COG0683@2|Bacteria,1MVV2@1224|Proteobacteria,2TRFU@28211|Alphaproteobacteria,3K2UM@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Receptor family ligand binding region MA20_13905 - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 CMS1_k127_1968519_17 871963.Desdi_3046 3.849e-69 247.0 COG4177@1|root,COG4177@2|Bacteria,1V7V4@1239|Firmicutes,24K2K@186801|Clostridia,265DU@186807|Peptococcaceae 186801|Clostridia U PFAM Branched-chain amino acid transport system permease component - - - ko:K01997,ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 CMS1_k127_1968519_19 706587.Desti_0843 4.115e-66 238.0 COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,42RHF@68525|delta/epsilon subdivisions,2WNRC@28221|Deltaproteobacteria 28221|Deltaproteobacteria E PFAM Branched-chain amino acid transport system permease component - - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 CMS1_k127_1968519_0 1342299.Z947_120 9.409e-287 891.0 COG2936@1|root,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,2TU0R@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Hydrolase CocE NonD family - - - ko:K06978 - - - - ko00000 - - - PepX_C,Peptidase_S15 CMS1_k127_1968519_10 1187851.A33M_2608 4.285e-102 342.0 COG2084@1|root,COG2084@2|Bacteria,1R889@1224|Proteobacteria,2TUEY@28211|Alphaproteobacteria 28211|Alphaproteobacteria I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - - - - - - - - - - NAD_binding_11,NAD_binding_2 CMS1_k127_1968519_12 1123072.AUDH01000010_gene3474 6.172e-88 303.0 COG2084@1|root,COG2084@2|Bacteria,1RBRD@1224|Proteobacteria,2U7V8@28211|Alphaproteobacteria 28211|Alphaproteobacteria I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - 1.1.1.31 ko:K00020 ko00280,ko01100,map00280,map01100 - R05066 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 CMS1_k127_1968519_21 1187851.A33M_2609 2.428e-49 179.0 COG3193@1|root,COG3193@2|Bacteria,1N08N@1224|Proteobacteria,2U5ES@28211|Alphaproteobacteria,3FEFG@34008|Rhodovulum 28211|Alphaproteobacteria S Haem-degrading - - - - - - - - - - - - Haem_degrading CMS1_k127_1968519_18 1298867.AUES01000010_gene5789 6.055e-69 241.0 COG0625@1|root,COG0625@2|Bacteria,1RA4Y@1224|Proteobacteria,2U5B6@28211|Alphaproteobacteria,3JWH3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O Glutathione S-transferase, N-terminal domain - - 5.2.1.2 ko:K01800 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R03181 RC00867 ko00000,ko00001,ko00002,ko01000 - - - GST_C,GST_C_2,GST_C_3,GST_N_3 CMS1_k127_1968519_15 113395.AXAI01000013_gene6847 1.578e-75 265.0 COG0673@1|root,COG0673@2|Bacteria,1MU8F@1224|Proteobacteria,2U12U@28211|Alphaproteobacteria,3JX1N@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C CMS1_k127_1968519_25 267608.RSp0038 2.03e-24 108.0 COG0824@1|root,COG0824@2|Bacteria,1MZPN@1224|Proteobacteria,2VTCV@28216|Betaproteobacteria,1K82U@119060|Burkholderiaceae 28216|Betaproteobacteria S thioesterase - - 3.1.2.23 ko:K01075 ko00130,ko00362,ko01100,ko01110,ko01120,map00130,map00362,map01100,map01110,map01120 - R01301 RC00004,RC00174 ko00000,ko00001,ko01000 - - - 4HBT,4HBT_2 CMS1_k127_1990176_4 472175.EL18_02924 9.038e-68 231.0 COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,2TRGP@28211|Alphaproteobacteria,43H5H@69277|Phyllobacteriaceae 28211|Alphaproteobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits atpD - 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_N CMS1_k127_1990176_6 441620.Mpop_1464 7.252e-17 85.0 2EHAQ@1|root,33B2K@2|Bacteria,1NJCK@1224|Proteobacteria,2UNJE@28211|Alphaproteobacteria,1JWBZ@119045|Methylobacteriaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_1990176_5 316055.RPE_0279 2.274e-45 168.0 COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,2UBXX@28211|Alphaproteobacteria,3JY3Y@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane atpC GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02113,ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_DE_N CMS1_k127_1990176_1 224911.27351605 4.414e-111 367.0 COG2421@1|root,COG2421@2|Bacteria,1MXKY@1224|Proteobacteria,2TSVA@28211|Alphaproteobacteria,3JW8A@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Acetamidase/Formamidase family - - - - - - - - - - - - FmdA_AmdA CMS1_k127_1990176_3 1187851.A33M_0860 4.346e-79 271.0 COG1051@1|root,COG1051@2|Bacteria,1QU0T@1224|Proteobacteria,2TW25@28211|Alphaproteobacteria,3FD7J@34008|Rhodovulum 28211|Alphaproteobacteria F Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage nudH - - ko:K08311 ko03018,map03018 - R10816 RC00002 ko00000,ko00001,ko01000,ko03019 - - - NUDIX CMS1_k127_1990176_2 316056.RPC_0167 1.253e-109 367.0 COG2861@1|root,COG2861@2|Bacteria,1N3JP@1224|Proteobacteria,2TUFD@28211|Alphaproteobacteria,3JRPC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Divergent polysaccharide deacetylase - - - ko:K09798 - - - - ko00000 - - - Polysacc_deac_2 CMS1_k127_1990176_0 316055.RPE_0271 5.454e-168 531.0 COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,2TRW2@28211|Alphaproteobacteria,3JRNU@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Belongs to the peptidase S41A family ctpA - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ_2,Peptidase_S41 CMS1_k127_1992389_4 883078.HMPREF9695_04031 1.299e-29 126.0 COG4961@1|root,COG4961@2|Bacteria,1N744@1224|Proteobacteria,2UGR2@28211|Alphaproteobacteria,3JWHX@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria U TadE-like protein - - - - - - - - - - - - TadE CMS1_k127_1992389_2 288000.BBta_7024 7.238e-47 175.0 COG4961@1|root,COG4961@2|Bacteria,1N3XK@1224|Proteobacteria,2UBRJ@28211|Alphaproteobacteria,3JXUI@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria U TadE-like protein - - - ko:K02651 ko04112,map04112 - - - ko00000,ko00001,ko02035,ko02044 - - - TadE CMS1_k127_1992389_3 1187851.A33M_3684 1.194e-45 172.0 COG4964@1|root,COG4964@2|Bacteria,1R3QI@1224|Proteobacteria,2UGFC@28211|Alphaproteobacteria 28211|Alphaproteobacteria U Flp pilus assembly protein secretin CpaC pilQ - - - - - - - - - - - T2SS-T3SS_pil_N CMS1_k127_1992389_5 316058.RPB_1787 2.917e-17 83.0 COG3847@1|root,COG3847@2|Bacteria,1NGVU@1224|Proteobacteria,2UJE8@28211|Alphaproteobacteria,3K1BG@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria U Flp/Fap pilin component pilA2 - - ko:K02651 ko04112,map04112 - - - ko00000,ko00001,ko02035,ko02044 - - - Flp_Fap CMS1_k127_1992389_1 1429916.X566_06855 2.996e-56 209.0 COG4960@1|root,COG4960@2|Bacteria,1RAYG@1224|Proteobacteria,2TSVX@28211|Alphaproteobacteria,3JYGP@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria OU Type IV leader peptidase family cpaA - 3.4.23.43 ko:K02278 - - - - ko00000,ko01000,ko02035,ko02044 - - - Peptidase_A24 CMS1_k127_1992389_0 323097.Nham_0392 1.69e-82 282.0 COG3745@1|root,COG3745@2|Bacteria,1MW75@1224|Proteobacteria,2TTPE@28211|Alphaproteobacteria,3JTGM@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria U pilus assembly protein CpaB cpaB - - ko:K02279 - - - - ko00000,ko02035,ko02044 - - - RcpC,SAF CMS1_k127_2000846_13 864069.MicloDRAFT_00024060 5.255e-37 141.0 COG1593@1|root,COG1593@2|Bacteria,1MUQE@1224|Proteobacteria,2TSSE@28211|Alphaproteobacteria,1JSA3@119045|Methylobacteriaceae 28211|Alphaproteobacteria G PFAM Malonyl-CoA decarboxylase matA - 4.1.1.9 ko:K01578 ko00410,ko00640,ko01100,ko04146,ko04152,map00410,map00640,map01100,map04146,map04152 - R00233 RC00040 ko00000,ko00001,ko01000 - - - MCD,MCD_N CMS1_k127_2000846_10 1380394.JADL01000007_gene4457 5.099e-91 305.0 COG1028@1|root,COG1028@2|Bacteria,1N8G3@1224|Proteobacteria,2TUTY@28211|Alphaproteobacteria,2JXEK@204441|Rhodospirillales 204441|Rhodospirillales IQ Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - - CMS1_k127_2000846_9 438753.AZC_4594 6.384e-109 360.0 COG0518@1|root,COG0518@2|Bacteria,1Q2PQ@1224|Proteobacteria,2U196@28211|Alphaproteobacteria,3F0JM@335928|Xanthobacteraceae 28211|Alphaproteobacteria F Peptidase C26 - - 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase CMS1_k127_2000846_5 426117.M446_1975 1.443e-164 532.0 COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,2TU11@28211|Alphaproteobacteria,1JRVG@119045|Methylobacteriaceae 28211|Alphaproteobacteria C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family glpD - 1.1.5.3 ko:K00111 ko00564,ko01110,map00564,map01110 - R00848 RC00029 ko00000,ko00001,ko01000 - - - DAO,DAO_C CMS1_k127_2000846_11 1187851.A33M_0385 3.664e-46 173.0 COG0745@1|root,COG0745@2|Bacteria,1QYPQ@1224|Proteobacteria,2TXUW@28211|Alphaproteobacteria 28211|Alphaproteobacteria T Response regulator receiver - - - - - - - - - - - - Response_reg CMS1_k127_2000846_0 1120792.JAFV01000001_gene2214 4.471e-216 681.0 COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,2TRD7@28211|Alphaproteobacteria,36XPE@31993|Methylocystaceae 28211|Alphaproteobacteria C FGGY family of carbohydrate kinases, N-terminal domain glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 - R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 - - - FGGY_C,FGGY_N CMS1_k127_2000846_12 744980.TRICHSKD4_0029 5.22e-39 151.0 COG0745@1|root,COG0745@2|Bacteria,1QYPQ@1224|Proteobacteria,2TXUW@28211|Alphaproteobacteria 28211|Alphaproteobacteria T Response regulator receiver - - - - - - - - - - - - Response_reg CMS1_k127_2000846_7 1028801.RG1141_CH02990 3.853e-129 423.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQMJ@28211|Alphaproteobacteria,4B8X7@82115|Rhizobiaceae 28211|Alphaproteobacteria P Part of the ABC transporter complex potABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system potA GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0016020,GO:0016021,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - ko:K11076 ko02010,map02010 M00300 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.2 - - ABC_tran,TOBE_2 CMS1_k127_2000846_6 316058.RPB_1455 8.328e-133 430.0 COG1176@1|root,COG1176@2|Bacteria,1MVGM@1224|Proteobacteria,2TSFD@28211|Alphaproteobacteria,3JSPC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P Binding-protein-dependent transport system inner membrane component potH GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - ko:K11075 ko02010,map02010 M00300 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.2 - - BPD_transp_1 CMS1_k127_2000846_8 1125973.JNLC01000010_gene1186 1.238e-112 384.0 COG1177@1|root,COG1177@2|Bacteria,1MVC5@1224|Proteobacteria,2TRRJ@28211|Alphaproteobacteria,3JT34@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Binding-protein-dependent transport system inner membrane component potI GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0016020,GO:0016021,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - ko:K11074 ko02010,map02010 M00300 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.2 - - BPD_transp_1 CMS1_k127_2000846_15 1187851.A33M_0380 1.925e-21 96.0 2E8GA@1|root,339WI@2|Bacteria,1NJTR@1224|Proteobacteria,2UM3X@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_2000846_2 1187851.A33M_0381 1.168e-195 629.0 COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,2TVI7@28211|Alphaproteobacteria,3FDAK@34008|Rhodovulum 28211|Alphaproteobacteria M AsmA-like C-terminal region MA20_03680 - - ko:K07289 - - - - ko00000 - - - AsmA,AsmA_2 CMS1_k127_2000846_3 1187851.A33M_1304 7.093e-191 612.0 COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,2TSTS@28211|Alphaproteobacteria,3FCSN@34008|Rhodovulum 28211|Alphaproteobacteria U Binding-protein-dependent transport system inner membrane component sfuB - - ko:K02011 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - BPD_transp_1 CMS1_k127_2000846_4 883078.HMPREF9695_03425 8.789e-167 531.0 COG1840@1|root,COG1840@2|Bacteria,1MUEG@1224|Proteobacteria,2TR6P@28211|Alphaproteobacteria,3JSIV@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P Bacterial extracellular solute-binding protein futA1 - - ko:K02012 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - SBP_bac_6,SBP_bac_8 CMS1_k127_2000846_1 196490.AUEZ01000051_gene390 3.2e-209 685.0 COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2TQU3@28211|Alphaproteobacteria,3JTYM@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T His Kinase A (phosphoacceptor) domain pdhS - - - - - - - - - - - HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9 CMS1_k127_2000846_14 1211115.ALIQ01000123_gene985 9.521e-23 103.0 COG5490@1|root,COG5490@2|Bacteria,1MZM4@1224|Proteobacteria,2UCPK@28211|Alphaproteobacteria,3NCN8@45404|Beijerinckiaceae 28211|Alphaproteobacteria S Phasin protein - - - - - - - - - - - - Phasin_2 CMS1_k127_2010185_2 1231392.OCGS_2830 1.386e-147 477.0 COG0183@1|root,COG0183@2|Bacteria,1MU8C@1224|Proteobacteria,2TS6P@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Belongs to the thiolase family - - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N CMS1_k127_2010185_0 247634.GPB2148_3709 1.121e-176 562.0 COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,1RQS1@1236|Gammaproteobacteria,1J93S@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Pyridine nucleotide-disulphide oxidoreductase sqrdl - 1.8.5.4 ko:K17218 ko00920,map00920 - R10152 RC03155 ko00000,ko00001,ko01000 - - - DUF442,Pyr_redox_2 CMS1_k127_2010185_1 1333998.M2A_0456 8.847e-164 529.0 COG1545@1|root,COG3425@1|root,COG1545@2|Bacteria,COG3425@2|Bacteria,1QV6D@1224|Proteobacteria,2TTB1@28211|Alphaproteobacteria 28211|Alphaproteobacteria I 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III - - - - - - - - - - - - ACP_syn_III_C,OB_aCoA_assoc CMS1_k127_2010185_3 1380394.JADL01000003_gene4779 4.643e-96 325.0 COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,2TRF8@28211|Alphaproteobacteria,2JPD2@204441|Rhodospirillales 204441|Rhodospirillales F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor pyrD - 1.3.5.2 ko:K00254 ko00240,ko01100,map00240,map01100 M00051 R01868 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh CMS1_k127_2010185_5 660470.Theba_0227 1.472e-40 166.0 COG4932@1|root,COG4932@2|Bacteria 2|Bacteria M domain protein - - - - - - - - - - - - CarboxypepD_reg,Collagen_bind,DUF11,DUF4015,DUF5011,Gram_pos_anchor,SdrD_B,SprB CMS1_k127_2010185_4 472759.Nhal_1036 3.904e-52 201.0 COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,1RMJ1@1236|Gammaproteobacteria,1WYP2@135613|Chromatiales 135613|Chromatiales L Belongs to the 'phage' integrase family - - - - - - - - - - - - Arm-DNA-bind_3,Phage_integrase CMS1_k127_2010185_7 1005058.UMN179_02348 1.26e-05 52.0 COG3311@1|root,COG3311@2|Bacteria,1QA6A@1224|Proteobacteria,1TG02@1236|Gammaproteobacteria,1YAJ6@135625|Pasteurellales 135625|Pasteurellales K Prophage CP4-57 regulatory protein (AlpA) - - - ko:K07733 - - - - ko00000,ko03000 - - - Phage_AlpA CMS1_k127_2010185_8 1331060.RLDS_11310 2.139e-05 55.0 COG2244@1|root,COG2244@2|Bacteria 2|Bacteria S polysaccharide biosynthetic process - - - - - - - - - - - - MatE,Polysacc_synt,Polysacc_synt_C CMS1_k127_2011658_1 883078.HMPREF9695_04139 1.142e-36 145.0 COG5330@1|root,COG5330@2|Bacteria,1R3VY@1224|Proteobacteria,2TUGG@28211|Alphaproteobacteria,3JUE9@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Uncharacterised protein conserved in bacteria (DUF2336) MA20_43740 - - - - - - - - - - - DUF2336 CMS1_k127_2011658_0 1187851.A33M_2319 4.091e-127 411.0 COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,2TTIX@28211|Alphaproteobacteria,3FD6K@34008|Rhodovulum 28211|Alphaproteobacteria U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides tatC - - ko:K03118 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - TatC CMS1_k127_20164_5 1187851.A33M_2868 2.793e-41 160.0 COG0318@1|root,COG0318@2|Bacteria,1MV6U@1224|Proteobacteria,2TT3F@28211|Alphaproteobacteria 28211|Alphaproteobacteria IQ AMP-binding enzyme MA20_13015 - - - - - - - - - - - AMP-binding CMS1_k127_20164_3 1187851.A33M_2870 2.544e-100 342.0 COG2199@1|root,COG3706@2|Bacteria,1N16G@1224|Proteobacteria,2U0J6@28211|Alphaproteobacteria 28211|Alphaproteobacteria T GGDEF domain MA20_13010 - - - - - - - - - - - - CMS1_k127_20164_4 196490.AUEZ01000025_gene2289 6.755e-85 290.0 COG2761@1|root,COG2761@2|Bacteria,1NXUB@1224|Proteobacteria,2TRJ6@28211|Alphaproteobacteria,3JS82@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria Q DSBA-like thioredoxin domain dsb - - - - - - - - - - - DSBA CMS1_k127_20164_2 266117.Rxyl_1758 3.755e-115 390.0 COG1062@1|root,COG1062@2|Bacteria,2GKJC@201174|Actinobacteria,4CQWP@84995|Rubrobacteria 84995|Rubrobacteria C Alcohol dehydrogenase GroES-like domain - - 1.1.1.90 ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 M00537,M00538 R01763,R02611,R04304,R05282,R05347,R05348 RC00087,RC00116 ko00000,ko00001,ko00002,ko01000 - - - ADH_N,ADH_zinc_N CMS1_k127_20164_0 1298867.AUES01000007_gene4982 0.0 1737.0 COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,2TR2H@28211|Alphaproteobacteria,3JU46@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF CMS1_k127_20164_6 1123229.AUBC01000005_gene780 1.573e-32 129.0 COG2938@1|root,COG2938@2|Bacteria,1N6SJ@1224|Proteobacteria,2UFF5@28211|Alphaproteobacteria,3K0G7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Flavinator of succinate dehydrogenase - - - ko:K09159 - - - - ko00000,ko02048 - - - Sdh5 CMS1_k127_20164_1 504832.OCAR_6213 2.09e-213 673.0 COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,2TR86@28211|Alphaproteobacteria,3JQTX@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L RecG wedge domain recG GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge CMS1_k127_2035044_8 388399.SSE37_24424 6.287e-23 98.0 COG3396@1|root,COG3396@2|Bacteria,1MXUK@1224|Proteobacteria,2TTIG@28211|Alphaproteobacteria 28211|Alphaproteobacteria S benzoyl-CoA oxygenase boxB - 1.14.13.208 ko:K15512 ko00362,map00362 - R09555 RC01739 ko00000,ko00001,ko01000 - - - - CMS1_k127_2035044_2 1244869.H261_19651 4.537e-175 563.0 COG1012@1|root,COG1012@2|Bacteria,1MWD4@1224|Proteobacteria,2TUPI@28211|Alphaproteobacteria,2JW5K@204441|Rhodospirillales 204441|Rhodospirillales C Aldehyde dehydrogenase family - - - - - - - - - - - - Aldedh CMS1_k127_2035044_1 1304877.KI519399_gene5684 1.925e-194 616.0 COG0642@1|root,COG0642@2|Bacteria,1MX6R@1224|Proteobacteria,2TS9N@28211|Alphaproteobacteria,3JWKT@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Histidine kinase - - - - - - - - - - - - HATPase_c CMS1_k127_2035044_3 1126627.BAWE01000004_gene4002 1.804e-121 393.0 COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,2TSV8@28211|Alphaproteobacteria,3JRM1@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K transcriptional regulator, winged helix family ctrA - - - - - - - - - - - Response_reg,Trans_reg_C CMS1_k127_2035044_7 1304877.KI519399_gene5686 3.468e-38 145.0 COG3212@1|root,COG3212@2|Bacteria,1NHDB@1224|Proteobacteria,2UJN5@28211|Alphaproteobacteria,3K19C@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Peptidase propeptide and YPEB domain - - - - - - - - - - - - PepSY,PepSY_2 CMS1_k127_2035044_5 1304877.KI519399_gene5688 1.823e-84 283.0 COG3658@1|root,COG3658@2|Bacteria,1RB03@1224|Proteobacteria,2VGBI@28211|Alphaproteobacteria 28211|Alphaproteobacteria C cytochrome - - - - - - - - - - - - Ni_hydr_CYTB CMS1_k127_2035044_0 316058.RPB_4656 4.486e-195 623.0 COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2TR3P@28211|Alphaproteobacteria,3JQQ5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I benzoate-CoA ligase MA20_22485 - 6.2.1.25,6.2.1.27 ko:K04105 ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220 - R01300,R01422 RC00004,RC00174 ko00000,ko00001,ko01000 - - - AMP-binding,AMP-binding_C CMS1_k127_2035044_4 258594.RPA0672 9.68e-103 344.0 COG1319@1|root,COG1319@2|Bacteria,1MVJS@1224|Proteobacteria,2U506@28211|Alphaproteobacteria 28211|Alphaproteobacteria C CO dehydrogenase flavoprotein C-terminal domain - - 1.3.7.9 ko:K04109 ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220 - R05316 RC00490 ko00000,ko00001,ko01000 - - - CO_deh_flav_C,FAD_binding_5 CMS1_k127_2035044_6 316055.RPE_0590 8.565e-70 241.0 COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TWGU@28211|Alphaproteobacteria,3JQT8@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - 1.17.1.4,1.2.5.3,1.3.7.9 ko:K00087,ko:K03520,ko:K04108 ko00230,ko00362,ko00627,ko01100,ko01120,ko01220,map00230,map00362,map00627,map01100,map01120,map01220 M00546 R01768,R02103,R05316,R11168 RC00143,RC00490,RC02800 ko00000,ko00001,ko00002,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2 CMS1_k127_20354_6 318996.AXAZ01000022_gene574 1.442e-27 114.0 COG1376@1|root,COG1376@2|Bacteria,1MVYT@1224|Proteobacteria,2U60K@28211|Alphaproteobacteria,3JT37@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S L,D-transpeptidase catalytic domain - - - - - - - - - - - - YkuD CMS1_k127_20354_2 622637.KE124770_gene147 1.241e-193 610.0 COG1697@1|root,COG1697@2|Bacteria,1NBFJ@1224|Proteobacteria 1224|Proteobacteria L DNA topoisomerase VI subunit A top6A - 5.99.1.3 ko:K03166 - - - - ko00000,ko01000,ko03032 - - - TP6A_N CMS1_k127_20354_1 622637.KE124770_gene148 9.658e-252 786.0 COG1389@1|root,COG1389@2|Bacteria,1R6T0@1224|Proteobacteria 1224|Proteobacteria L Relaxes both positive and negative superturns and exhibits a strong decatenase activity top6B - 5.99.1.3 ko:K03167 - - - - ko00000,ko01000,ko03032 - - - HATPase_c,HATPase_c_3,Topo-VIb_trans CMS1_k127_20354_4 398525.KB900701_gene5904 1.004e-116 383.0 COG1893@1|root,COG1893@2|Bacteria,1MX5M@1224|Proteobacteria,2TVRD@28211|Alphaproteobacteria,3K5Z9@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - - - - - - - - - - ApbA,ApbA_C CMS1_k127_20354_3 323097.Nham_2886 1.138e-160 523.0 2EB2V@1|root,3353M@2|Bacteria,1NDM7@1224|Proteobacteria,2TV7H@28211|Alphaproteobacteria,3JQS2@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Domain of unknown function (DUF4403) MA20_01580 - - - - - - - - - - - DUF4403 CMS1_k127_20354_5 1197906.CAJQ02000023_gene2466 1.036e-31 131.0 2ENBK@1|root,33FZ7@2|Bacteria,1N3KU@1224|Proteobacteria,2UE58@28211|Alphaproteobacteria,3K5UU@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_20354_0 1230476.C207_05649 1.961e-262 813.0 COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,2TS0S@28211|Alphaproteobacteria,3JUK5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction thiC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 ko:K03147 ko00730,ko01100,map00730,map01100 M00127 R03472 RC03251,RC03252 ko00000,ko00001,ko00002,ko01000 - - - ThiC-associated,ThiC_Rad_SAM CMS1_k127_2039953_14 1038867.AXAY01000009_gene5751 4.573e-53 189.0 COG0586@1|root,COG0586@2|Bacteria,1R0F3@1224|Proteobacteria,2U088@28211|Alphaproteobacteria,3K35U@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S SNARE associated Golgi protein - - - - - - - - - - - - SNARE_assoc CMS1_k127_2039953_11 1267005.KB911255_gene2772 8.076e-80 282.0 COG0628@1|root,COG0628@2|Bacteria,1MXXU@1224|Proteobacteria,2TVPN@28211|Alphaproteobacteria,3N9GN@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria S AI-2E family transporter - - - - - - - - - - - - AI-2E_transport CMS1_k127_2039953_0 1038859.AXAU01000001_gene3452 0.0 1055.0 COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,2TQZV@28211|Alphaproteobacteria,3JRV8@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parE - - ko:K02622 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim CMS1_k127_2039953_21 1245469.S58_53960 1.614e-05 53.0 2A6QX@1|root,30VJ0@2|Bacteria,1RA5F@1224|Proteobacteria,2U6RF@28211|Alphaproteobacteria,3JYBB@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_2039953_4 323097.Nham_3773 1.405e-177 568.0 COG3104@1|root,COG3104@2|Bacteria,1MW6W@1224|Proteobacteria,2U15C@28211|Alphaproteobacteria 28211|Alphaproteobacteria E amino acid peptide transporter - - - ko:K03305 - - - - ko00000 2.A.17 - - MFS_1,PTR2 CMS1_k127_2039953_5 1123229.AUBC01000005_gene716 2.931e-149 481.0 COG0654@1|root,COG0654@2|Bacteria,1MV8T@1224|Proteobacteria,2TRB8@28211|Alphaproteobacteria,3JSNQ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria CH FAD binding domain - - 1.14.13.2 ko:K00481 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 - R01298 RC00046 ko00000,ko00001,ko01000 - - - FAD_binding_3 CMS1_k127_2039953_16 1187851.A33M_1047 1.149e-40 156.0 COG2020@1|root,COG2020@2|Bacteria 2|Bacteria O methyltransferase activity - - - - - - - - - - - - PEMT CMS1_k127_2039953_12 196490.AUEZ01000051_gene419 5.957e-78 267.0 COG2267@1|root,COG2267@2|Bacteria,1QUZX@1224|Proteobacteria,2TWE4@28211|Alphaproteobacteria,3JTRZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Thioesterase domain - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 CMS1_k127_2039953_3 1429916.X566_19720 8.025e-198 625.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2TR6Q@28211|Alphaproteobacteria,3JS2G@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L Belongs to the DEAD box helicase family rhlE - 3.6.4.13 ko:K03732,ko:K11927 ko03018,map03018 M00394 - - ko00000,ko00001,ko00002,ko01000,ko03019 - - - DEAD,Helicase_C CMS1_k127_2039953_6 1187851.A33M_3378 1.077e-135 440.0 COG2199@1|root,COG3706@2|Bacteria,1NC00@1224|Proteobacteria,2TU9T@28211|Alphaproteobacteria 28211|Alphaproteobacteria T Diguanylate cyclase MA20_30680 - 2.7.7.65 ko:K13590 ko04112,map04112 - - - ko00000,ko00001,ko01000 - - - GGDEF CMS1_k127_2039953_18 316058.RPB_2987 2.35e-28 124.0 COG3070@1|root,COG3070@2|Bacteria,1N8X8@1224|Proteobacteria,2UFNC@28211|Alphaproteobacteria,3JYWH@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K TfoX N-terminal domain MA20_30690 - - ko:K07343 - - - - ko00000 - - - TfoX_N CMS1_k127_2039953_13 883080.HMPREF9697_00965 1.848e-56 199.0 COG0316@1|root,COG0316@2|Bacteria,1RH6T@1224|Proteobacteria,2UBWJ@28211|Alphaproteobacteria,3JYPC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Belongs to the HesB IscA family iscA GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009058,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0018130,GO:0019438,GO:0019538,GO:0022607,GO:0031163,GO:0031974,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0051604,GO:0070013,GO:0071704,GO:0071840,GO:0097428,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - ko:K13628 - - - - ko00000,ko03016 - - - Fe-S_biosyn CMS1_k127_2039953_15 1187851.A33M_3376 1.042e-46 174.0 COG2151@1|root,COG2151@2|Bacteria,1MZ9Y@1224|Proteobacteria,2U72U@28211|Alphaproteobacteria,3FDF2@34008|Rhodovulum 28211|Alphaproteobacteria S Pfam:DUF59 MA20_30700 - - - - - - - - - - - FeS_assembly_P CMS1_k127_2039953_2 1187851.A33M_3375 5.49e-223 696.0 COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,2TRNY@28211|Alphaproteobacteria,3FCS5@34008|Rhodovulum 28211|Alphaproteobacteria E Cys/Met metabolism PLP-dependent enzyme sufS - 2.8.1.7,4.4.1.16 ko:K11717 ko00450,ko01100,map00450,map01100 - R03599,R11528 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000 - - - Aminotran_5 CMS1_k127_2039953_7 78245.Xaut_0086 2.648e-130 437.0 COG0719@1|root,COG0719@2|Bacteria,1MVK0@1224|Proteobacteria,2TTK9@28211|Alphaproteobacteria,3F0J1@335928|Xanthobacteraceae 28211|Alphaproteobacteria O Uncharacterized protein family (UPF0051) sufD - - ko:K09015 - - - - ko00000 - - - UPF0051 CMS1_k127_2039953_10 316055.RPE_2966 1.634e-119 389.0 COG0396@1|root,COG0396@2|Bacteria,1MUGK@1224|Proteobacteria,2TS8T@28211|Alphaproteobacteria,3JTK7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O ATPases associated with a variety of cellular activities sufC - - ko:K09013 - - - - ko00000,ko02000 - - - ABC_tran CMS1_k127_2039953_17 1535287.JP74_09120 9.848e-38 162.0 COG3837@1|root,COG3837@2|Bacteria,1N15Q@1224|Proteobacteria,2UDER@28211|Alphaproteobacteria,3N73T@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria S Cupin domain manC - - - - - - - - - - - Cupin_2 CMS1_k127_2039953_1 391937.NA2_18685 4.836e-286 883.0 COG0719@1|root,COG0719@2|Bacteria,1MVKY@1224|Proteobacteria,2TRU6@28211|Alphaproteobacteria,43I2X@69277|Phyllobacteriaceae 28211|Alphaproteobacteria O COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component sufB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009536,GO:0009842,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 - ko:K09014 - - - - ko00000 - - - UPF0051 CMS1_k127_2039953_8 1187851.A33M_3369 2.7e-127 418.0 COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,2TSQE@28211|Alphaproteobacteria,3FCWX@34008|Rhodovulum 28211|Alphaproteobacteria E Aminotransferase class-V nifS GO:0000096,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006464,GO:0006520,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016043,GO:0016226,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0018282,GO:0018283,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0031071,GO:0031163,GO:0031974,GO:0031981,GO:0032324,GO:0034641,GO:0036211,GO:0042278,GO:0042802,GO:0042803,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043545,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0046983,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 CMS1_k127_2039953_9 1187851.A33M_3368 4.068e-124 400.0 COG2945@1|root,COG2945@2|Bacteria,1MUDY@1224|Proteobacteria,2TRMI@28211|Alphaproteobacteria,3FCQA@34008|Rhodovulum 28211|Alphaproteobacteria S X-Pro dipeptidyl-peptidase (S15 family) QU41_16170 - - ko:K07018 - - - - ko00000 - - - Hydrolase_4,Peptidase_S15 CMS1_k127_2039953_20 335659.S23_62270 2.504e-27 111.0 297CE@1|root,2ZUJZ@2|Bacteria,1N70S@1224|Proteobacteria,2UHEE@28211|Alphaproteobacteria,3K0J5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - MA20_06225 - - - - - - - - - - - - CMS1_k127_2039953_19 269796.Rru_A0045 1.618e-27 112.0 COG0304@1|root,COG0304@2|Bacteria,1MV30@1224|Proteobacteria,2TRYK@28211|Alphaproteobacteria,2JW3W@204441|Rhodospirillales 204441|Rhodospirillales IQ Beta-ketoacyl synthase, C-terminal domain - - - ko:K14660 - - - - ko00000,ko01000 - - - Ketoacyl-synt_C,ketoacyl-synt CMS1_k127_2040592_0 1187851.A33M_4310 4.756e-132 428.0 COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,2TUHH@28211|Alphaproteobacteria,3FD1X@34008|Rhodovulum 28211|Alphaproteobacteria M Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis lpxC - 3.5.1.108 ko:K02535 ko00540,ko01100,map00540,map01100 M00060 R04587 RC00166,RC00300 ko00000,ko00001,ko00002,ko01000,ko01005 - - - LpxC CMS1_k127_2045211_2 450851.PHZ_c3369 1.206e-26 111.0 COG0523@1|root,COG0523@2|Bacteria,1MVZV@1224|Proteobacteria,2TS4B@28211|Alphaproteobacteria,2KFAH@204458|Caulobacterales 204458|Caulobacterales S Cobalamin synthesis protein - - - - - - - - - - - - CobW_C,cobW CMS1_k127_2045211_1 443152.MDG893_15427 1.317e-81 281.0 COG0684@1|root,COG0684@2|Bacteria,1MW9P@1224|Proteobacteria,1RNV3@1236|Gammaproteobacteria,466ME@72275|Alteromonadaceae 1236|Gammaproteobacteria H Aldolase/RraA ligK GO:0003674,GO:0003824,GO:0006082,GO:0006725,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0017144,GO:0018918,GO:0018958,GO:0019336,GO:0019396,GO:0019439,GO:0019752,GO:0032787,GO:0042537,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901575,GO:1901615,GO:1901616 4.1.3.17 ko:K10218 ko00362,ko00660,ko01120,map00362,map00660,map01120 - R00008,R00350 RC00067,RC00502,RC01205 ko00000,ko00001,ko01000 - - - RraA-like CMS1_k127_2045211_0 443152.MDG893_15422 1.332e-191 604.0 COG2159@1|root,COG2159@2|Bacteria,1MVHB@1224|Proteobacteria,1RMYJ@1236|Gammaproteobacteria,469V2@72275|Alteromonadaceae 1236|Gammaproteobacteria S Amidohydrolase fldW - 4.1.1.45,4.2.1.83 ko:K03392,ko:K10220 ko00362,ko00380,ko01100,ko01120,map00362,map00380,map01100,map01120 M00038 R04323,R04478 RC00498,RC00779 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_2 CMS1_k127_2046690_0 935261.JAGL01000009_gene1222 7.304e-137 447.0 COG0683@1|root,COG0683@2|Bacteria,1MV3Y@1224|Proteobacteria,2TU2B@28211|Alphaproteobacteria,43HZY@69277|Phyllobacteriaceae 28211|Alphaproteobacteria E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component MA20_07775 - - ko:K01999,ko:K11959 ko02010,ko02024,map02010,map02024 M00237,M00323 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4,3.A.1.4.4,3.A.1.4.5 - - Peripla_BP_6 CMS1_k127_2046690_2 1381123.AYOD01000015_gene2539 1.678e-108 358.0 COG0559@1|root,COG0559@2|Bacteria,1NQYP@1224|Proteobacteria,2TSH6@28211|Alphaproteobacteria,43HDY@69277|Phyllobacteriaceae 28211|Alphaproteobacteria E Branched-chain amino acid transport system / permease component MA20_07780 - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 CMS1_k127_2046690_1 1381123.AYOD01000015_gene2540 2.495e-126 411.0 COG4177@1|root,COG4177@2|Bacteria,1MYF5@1224|Proteobacteria,2TUHM@28211|Alphaproteobacteria,43GR5@69277|Phyllobacteriaceae 28211|Alphaproteobacteria E Branched-chain amino acid transport system permease component MA20_07785 - - ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 CMS1_k127_2046690_3 935261.JAGL01000009_gene1225 3.676e-90 317.0 COG0411@1|root,COG0411@2|Bacteria,1MXHT@1224|Proteobacteria,2TSIU@28211|Alphaproteobacteria,43JPZ@69277|Phyllobacteriaceae 28211|Alphaproteobacteria E branched-chain amino acid MA20_07790 - - ko:K01995,ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C CMS1_k127_2046690_4 267608.RSc2245 6.934e-43 161.0 COG0410@1|root,COG0410@2|Bacteria,1MUFR@1224|Proteobacteria,2VM45@28216|Betaproteobacteria,1K0FZ@119060|Burkholderiaceae 28216|Betaproteobacteria E ABC transporter - - - ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran CMS1_k127_2053747_4 1380394.JADL01000001_gene3039 8.324e-68 241.0 COG4177@1|root,COG4177@2|Bacteria,1MYF5@1224|Proteobacteria,2TUHM@28211|Alphaproteobacteria,2JS28@204441|Rhodospirillales 204441|Rhodospirillales E Branched-chain amino acid transport system / permease component - - - ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 CMS1_k127_2053747_1 1380394.JADL01000001_gene3040 9.7e-86 292.0 COG0559@1|root,COG0559@2|Bacteria,1NQYP@1224|Proteobacteria,2TSH6@28211|Alphaproteobacteria,2JRU1@204441|Rhodospirillales 204441|Rhodospirillales E Branched-chain amino acid transport system / permease component - - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 CMS1_k127_2053747_2 1380394.JADL01000001_gene3041 9.343e-81 284.0 COG0683@1|root,COG0683@2|Bacteria,1MV3Y@1224|Proteobacteria,2TU2B@28211|Alphaproteobacteria,2JQHQ@204441|Rhodospirillales 204441|Rhodospirillales E Receptor family ligand binding region - - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 CMS1_k127_2053747_0 1411123.JQNH01000001_gene267 1.861e-203 639.0 COG0654@1|root,COG0654@2|Bacteria,1MXEW@1224|Proteobacteria,2TRRC@28211|Alphaproteobacteria 28211|Alphaproteobacteria CH COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases MA20_38140 - 1.14.13.218 ko:K20940 ko00405,ko01130,map00405,map01130 M00835 - - ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 CMS1_k127_2053747_3 1502851.FG93_05635 8.656e-72 246.0 COG0662@1|root,COG0662@2|Bacteria,1QWSD@1224|Proteobacteria,2TX3S@28211|Alphaproteobacteria,3JUV4@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G Cupin MA20_38135 - - - - - - - - - - - Cupin_2 CMS1_k127_2053747_5 309798.COPRO5265_0558 1.091e-50 198.0 COG1028@1|root,COG1028@2|Bacteria,1TR1J@1239|Firmicutes,248AA@186801|Clostridia,42F7Y@68295|Thermoanaerobacterales 186801|Clostridia IQ PFAM Short-chain dehydrogenase reductase SDR - - - - - - - - - - - - adh_short_C2 CMS1_k127_2053747_6 1041159.AZUW01000023_gene3045 8.362e-43 164.0 COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,2TS2B@28211|Alphaproteobacteria,4B7JX@82115|Rhizobiaceae 28211|Alphaproteobacteria L DNA helicase uvrD - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C CMS1_k127_2070743_3 1123393.KB891326_gene82 2.931e-07 52.0 COG2843@1|root,COG2843@2|Bacteria,1P1MG@1224|Proteobacteria,2VIGZ@28216|Betaproteobacteria,1KTA6@119069|Hydrogenophilales 119069|Hydrogenophilales M Bacterial capsule synthesis protein PGA_cap - - - ko:K07282 - - - - ko00000 - - - PGA_cap CMS1_k127_2070743_0 1123393.KB891326_gene81 9.976e-103 340.0 COG0177@1|root,COG0177@2|Bacteria,1N2HB@1224|Proteobacteria 1224|Proteobacteria L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate - - - - - - - - - - - - - CMS1_k127_2070743_1 1123393.KB891326_gene80 1.155e-89 299.0 COG1544@1|root,COG1544@2|Bacteria,1RJ55@1224|Proteobacteria,2VR5Q@28216|Betaproteobacteria,1KSAT@119069|Hydrogenophilales 119069|Hydrogenophilales J 'Cold-shock' DNA-binding domain - - - - - - - - - - - - CSD,Ribosomal_S30AE CMS1_k127_2070743_2 748247.AZKH_1502 4.375e-69 240.0 COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,2VHEH@28216|Betaproteobacteria,2KUWF@206389|Rhodocyclales 28216|Betaproteobacteria O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins - - - ko:K03686 - - - - ko00000,ko03029,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG CMS1_k127_207559_7 891968.Anamo_1375 1.209e-22 102.0 COG3333@1|root,COG3333@2|Bacteria,3TAA8@508458|Synergistetes 508458|Synergistetes S PFAM Tripartite tricarboxylate transporter TctA family - - - ko:K07793 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctA CMS1_k127_207559_10 716928.AJQT01000061_gene4256 2.902e-05 53.0 2E4UV@1|root,32ZP8@2|Bacteria,1N4X4@1224|Proteobacteria,2U7VJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter TctB family - - - ko:K07794 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctB CMS1_k127_207559_1 1380394.JADL01000005_gene5556 1.803e-67 236.0 COG2761@1|root,COG2761@2|Bacteria,1NXUB@1224|Proteobacteria,2TRJ6@28211|Alphaproteobacteria,2JS92@204441|Rhodospirillales 204441|Rhodospirillales Q dithiol-disulfide isomerase involved in polyketide biosynthesis - - - - - - - - - - - - DSBA CMS1_k127_207559_4 1294143.H681_11115 2.393e-51 191.0 2F4QS@1|root,33XDT@2|Bacteria,1NW62@1224|Proteobacteria 1224|Proteobacteria S NIPSNAP - - - - - - - - - - - - NIPSNAP CMS1_k127_207559_6 264198.Reut_A1134 6.356e-43 161.0 COG2350@1|root,COG2350@2|Bacteria,1N0W9@1224|Proteobacteria,2WE22@28216|Betaproteobacteria,1KBFZ@119060|Burkholderiaceae 28216|Betaproteobacteria S YCII-related domain - - - - - - - - - - - - YCII CMS1_k127_207559_8 1395516.PMO01_11800 9.183e-10 65.0 2EKSU@1|root,33EGJ@2|Bacteria,1NGQH@1224|Proteobacteria,1ST4J@1236|Gammaproteobacteria 1236|Gammaproteobacteria S cobalt transporter cbtB - - - - - - - - - - - CbtB CMS1_k127_207559_3 1192868.CAIU01000008_gene900 7.147e-57 207.0 COG5446@1|root,COG5446@2|Bacteria,1RBWQ@1224|Proteobacteria,2U9NN@28211|Alphaproteobacteria,43IPW@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S cobalt transporter, subunit CbtA cbtA - - - - - - - - - - - CbtA CMS1_k127_207559_5 1057002.KB905370_gene1391 3.527e-48 177.0 COG2020@1|root,COG2020@2|Bacteria,1MZ7S@1224|Proteobacteria,2UAQH@28211|Alphaproteobacteria,4BMR4@82115|Rhizobiaceae 28211|Alphaproteobacteria O Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - - - - - - - - - - PEMT CMS1_k127_207559_0 1282876.BAOK01000001_gene2353 7.105e-107 356.0 2DBIF@1|root,2Z9FG@2|Bacteria,1QYR5@1224|Proteobacteria,2TTVX@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_207559_9 570967.JMLV01000001_gene2838 4.306e-09 68.0 COG3087@1|root,COG3087@2|Bacteria,1MXII@1224|Proteobacteria,2TTG3@28211|Alphaproteobacteria,2JT9Z@204441|Rhodospirillales 204441|Rhodospirillales D Sporulation related domain - - - - - - - - - - - - SPOR CMS1_k127_2077843_1 195250.CM001776_gene3668 2.29e-37 149.0 COG3495@1|root,COG3495@2|Bacteria,1GPMD@1117|Cyanobacteria,1H3HM@1129|Synechococcus 1117|Cyanobacteria S Protein of unknown function (DUF3299) - - - - - - - - - - - - DUF3299 CMS1_k127_2077843_0 648757.Rvan_0576 6.738e-39 153.0 COG4531@1|root,COG4531@2|Bacteria,1N099@1224|Proteobacteria,2UHIQ@28211|Alphaproteobacteria,3N8RF@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria P Protein of unknown function (DUF2796) - - - - - - - - - - - - DUF2796 CMS1_k127_2087017_0 991905.SL003B_3341 1.652e-107 366.0 COG4907@1|root,COG4907@2|Bacteria,1MXPY@1224|Proteobacteria,2TUBP@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Predicted membrane protein (DUF2207) - - - - - - - - - - - - DUF2207 CMS1_k127_2099561_7 1123060.JONP01000036_gene3567 5.364e-16 80.0 COG2079@1|root,COG2079@2|Bacteria,1MU3X@1224|Proteobacteria,2U4FQ@28211|Alphaproteobacteria,2JV6F@204441|Rhodospirillales 204441|Rhodospirillales S MmgE/PrpD family - - - - - - - - - - - - MmgE_PrpD CMS1_k127_2099561_2 1123060.JONP01000036_gene3568 1.199e-157 509.0 COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TS6V@28211|Alphaproteobacteria 28211|Alphaproteobacteria C CoA-transferase family III - - - - - - - - - - - - CoA_transf_3 CMS1_k127_2099561_3 1123060.JONP01000036_gene3569 2.531e-129 418.0 COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,2U2KH@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Belongs to the enoyl-CoA hydratase isomerase family - - 4.2.1.17 ko:K01715,ko:K16880 ko00365,ko00650,ko01120,ko01200,map00365,map00650,map01120,map01200 - R03026,R10210 RC00004,RC00831,RC01903 ko00000,ko00001,ko01000 - - - ECH_1 CMS1_k127_2099561_0 1123060.JONP01000036_gene3570 2.736e-206 646.0 COG1960@1|root,COG1960@2|Bacteria,1MVAH@1224|Proteobacteria,2TR02@28211|Alphaproteobacteria 28211|Alphaproteobacteria I acyl-CoA dehydrogenase - - 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N CMS1_k127_2099561_5 1297570.MESS4_30020 2.399e-60 217.0 COG1028@1|root,COG1028@2|Bacteria,1R3U8@1224|Proteobacteria,2U1SI@28211|Alphaproteobacteria 28211|Alphaproteobacteria IQ KR domain - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 CMS1_k127_2099561_1 314270.RB2083_2750 2.243e-159 515.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQNK@28211|Alphaproteobacteria 1224|Proteobacteria G COG1593 TRAP-type C4-dicarboxylate transport system, large permease component MA20_18685 - - - - - - - - - - - DctM CMS1_k127_2099561_6 314270.RB2083_529 1.287e-23 107.0 COG3090@1|root,COG3090@2|Bacteria,1NCEM@1224|Proteobacteria,2UFJP@28211|Alphaproteobacteria 28211|Alphaproteobacteria G COG3090 TRAP-type C4-dicarboxylate transport system, small permease component - - - - - - - - - - - - DctQ CMS1_k127_2099561_4 314270.RB2083_60 1.312e-93 318.0 COG1638@1|root,COG1638@2|Bacteria,1MVHI@1224|Proteobacteria,2TRHD@28211|Alphaproteobacteria 28211|Alphaproteobacteria G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - - - - - - - - - - DctP CMS1_k127_2126489_0 265072.Mfla_2518 1.729e-147 495.0 COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,2VHY8@28216|Betaproteobacteria,2KKXA@206350|Nitrosomonadales 206350|Nitrosomonadales NU Neisseria PilC beta-propeller domain - - - ko:K02674 - - - - ko00000,ko02035,ko02044 - - - Neisseria_PilC CMS1_k127_2127712_1 1187851.A33M_1969 4.598e-87 291.0 COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2TVTA@28211|Alphaproteobacteria,3FDPP@34008|Rhodovulum 28211|Alphaproteobacteria M DegT/DnrJ/EryC1/StrS aminotransferase family - - - - - - - - - - - - DegT_DnrJ_EryC1 CMS1_k127_2127712_0 395964.KE386496_gene2505 1.893e-161 511.0 COG0175@1|root,COG0175@2|Bacteria,1MUCZ@1224|Proteobacteria,2TT2D@28211|Alphaproteobacteria,3NACY@45404|Beijerinckiaceae 28211|Alphaproteobacteria EH Phosphoadenosine phosphosulfate reductase family cysD - 2.7.7.4 ko:K00957 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00529,R04929 RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - PAPS_reduct CMS1_k127_2127712_2 876269.ARWA01000001_gene1298 1.169e-46 171.0 COG0529@1|root,COG2895@1|root,COG0529@2|Bacteria,COG2895@2|Bacteria,1MUD9@1224|Proteobacteria,2TQNJ@28211|Alphaproteobacteria,3NARA@45404|Beijerinckiaceae 28211|Alphaproteobacteria P Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily cysC - 2.7.1.25,2.7.7.4 ko:K00955 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176 R00509,R00529,R04928,R04929 RC00002,RC00078,RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - APS_kinase,GTP_EFTU CMS1_k127_2128610_4 1187851.A33M_2655 1.905e-43 162.0 COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,2TR76@28211|Alphaproteobacteria,3FD4G@34008|Rhodovulum 28211|Alphaproteobacteria S Predicted permease YjgP/YjgQ family lptG - - ko:K11720 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - - YjgP_YjgQ CMS1_k127_2128610_1 316056.RPC_2313 2.254e-130 428.0 COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,2TQUB@28211|Alphaproteobacteria,3JSK7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Permease MA20_28210 - - ko:K07091 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko02000 1.B.42.1 - - YjgP_YjgQ CMS1_k127_2128610_0 1126627.BAWE01000004_gene3980 7.385e-220 691.0 COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,2TQU9@28211|Alphaproteobacteria,3JUA7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides pepA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.11.1 ko:K01255 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M17,Peptidase_M17_N CMS1_k127_2128610_2 288000.BBta_3833 4.212e-64 224.0 COG2927@1|root,COG2927@2|Bacteria,1RGVC@1224|Proteobacteria,2U94V@28211|Alphaproteobacteria,3JY2F@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L DNA polymerase III, chi subunit holC - 2.7.7.7 ko:K02339 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_chi CMS1_k127_2128610_5 1429916.X566_19215 3.186e-07 61.0 293K0@1|root,2ZR1Z@2|Bacteria,1QXT6@1224|Proteobacteria,2U07A@28211|Alphaproteobacteria,3JZ3X@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_2128610_3 1187851.A33M_2643 5.157e-49 179.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2TQRZ@28211|Alphaproteobacteria,3FCPB@34008|Rhodovulum 28211|Alphaproteobacteria S ABC transporter yheS GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K06158 - - - - ko00000,ko03012 - - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn CMS1_k127_2133751_0 290397.Adeh_2245 5.464e-219 687.0 COG1012@1|root,COG1012@2|Bacteria,1MUHV@1224|Proteobacteria,42MVJ@68525|delta/epsilon subdivisions,2WKM4@28221|Deltaproteobacteria,2YTUB@29|Myxococcales 28221|Deltaproteobacteria C Aldehyde dehydrogenase family mmsA - 1.2.1.18,1.2.1.27 ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 M00013 R00705,R00706,R00922,R00935 RC00004,RC02723,RC02817 ko00000,ko00001,ko00002,ko01000 - - - Aldedh CMS1_k127_2133751_1 1288494.EBAPG3_24560 6.471e-134 437.0 COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,2VH1F@28216|Betaproteobacteria,372TF@32003|Nitrosomonadales 28216|Betaproteobacteria KT PFAM Metal-dependent phosphohydrolase, HD - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - CHASE2,GAF_2,HD CMS1_k127_2133751_2 1163617.SCD_n02136 6.513e-105 345.0 28M8G@1|root,2ZAMM@2|Bacteria,1MVBT@1224|Proteobacteria,2VRKU@28216|Betaproteobacteria 28216|Betaproteobacteria S RES - - - - - - - - - - - - RES CMS1_k127_2133751_3 1163617.SCD_n02135 7.525e-56 197.0 COG5642@1|root,COG5642@2|Bacteria,1N2DF@1224|Proteobacteria,2VUY5@28216|Betaproteobacteria 28216|Betaproteobacteria S Protein of unknown function (DUF2384) - - - - - - - - - - - - DUF2384 CMS1_k127_2133751_4 1123392.AQWL01000007_gene883 3.666e-11 63.0 COG1926@1|root,COG1926@2|Bacteria,1RAG8@1224|Proteobacteria,2VPNZ@28216|Betaproteobacteria,1KS7V@119069|Hydrogenophilales 119069|Hydrogenophilales S Phosphoribosyl transferase domain - - - - - - - - - - - - Pribosyltran CMS1_k127_2136392_14 936455.KI421499_gene1777 1.768e-45 166.0 COG0431@1|root,COG0431@2|Bacteria,1RAFI@1224|Proteobacteria,2VG85@28211|Alphaproteobacteria,3K0N1@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Flavodoxin-like fold - - - ko:K19784 - - - - ko00000 - - - FMN_red CMS1_k127_2136392_15 316058.RPB_1638 1.988e-35 156.0 COG2911@1|root,COG2931@1|root,COG3420@1|root,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3420@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,3JVDZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria MQ COG2931 RTX toxins and related Ca2 -binding proteins - - - - - - - - - - - - Collar,HemolysinCabind,Peptidase_M10_C CMS1_k127_2136392_20 685035.ADAE01000017_gene260 1.153e-07 65.0 COG2931@1|root,COG4932@1|root,COG2931@2|Bacteria,COG4932@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q COG2931 RTX toxins and related Ca2 -binding proteins - - 3.4.24.40 ko:K01406 ko01503,map01503 - - - ko00000,ko00001,ko01000,ko01002 - - - HemolysinCabind,PPC,Peptidase_M10_C,VCBS CMS1_k127_2136392_19 797302.Halru_2781 2.197e-08 68.0 COG1404@1|root,COG1470@1|root,COG3420@1|root,arCOG06738@1|root,arCOG00702@2157|Archaea,arCOG02087@2157|Archaea,arCOG02519@2157|Archaea,arCOG06738@2157|Archaea,2XTGN@28890|Euryarchaeota,23TTV@183963|Halobacteria 183963|Halobacteria O Belongs to the peptidase S8 family - - - - - - - - - - - - CarboxypepD_reg,Cohesin,Peptidase_S8 CMS1_k127_2136392_3 345341.KUTG_08851 1.044e-137 444.0 COG0596@1|root,COG0596@2|Bacteria,2I99I@201174|Actinobacteria,4E4K3@85010|Pseudonocardiales 201174|Actinobacteria S Alpha/beta hydrolase family dhaA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009410,GO:0009987,GO:0016020,GO:0016787,GO:0016824,GO:0018786,GO:0019120,GO:0030312,GO:0042178,GO:0042197,GO:0042206,GO:0042221,GO:0044237,GO:0044248,GO:0044464,GO:0050896,GO:0051716,GO:0070887,GO:0071466,GO:0071704,GO:0071944,GO:1901575 3.8.1.5 ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05284,R05367,R05368,R05369,R05370,R07669,R07670 RC01317,RC01340,RC01341,RC02013 ko00000,ko00001,ko01000 - - - Abhydrolase_1 CMS1_k127_2136392_16 288000.BBta_2401 1.058e-22 102.0 COG2259@1|root,COG2259@2|Bacteria,1RCKY@1224|Proteobacteria,2U6KP@28211|Alphaproteobacteria,3JYKN@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S DoxX - - - ko:K15977 - - - - ko00000 - - - DoxX CMS1_k127_2136392_6 991905.SL003B_2483 1.68e-92 307.0 28N0F@1|root,2ZB6V@2|Bacteria,1R4J3@1224|Proteobacteria,2VCSJ@28211|Alphaproteobacteria,4BSIC@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria S SnoaL-like domain - - - - - - - - - - - - SnoaL_4 CMS1_k127_2136392_9 1218352.B597_002415 5.398e-79 271.0 COG1028@1|root,COG1028@2|Bacteria,1PG34@1224|Proteobacteria,1RWX6@1236|Gammaproteobacteria,1Z3TP@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria IQ KR domain - - - - - - - - - - - - adh_short_C2 CMS1_k127_2136392_4 1097668.BYI23_C002820 1.935e-114 380.0 COG3435@1|root,COG3435@2|Bacteria,1MVJP@1224|Proteobacteria,2VM1T@28216|Betaproteobacteria,1JZPS@119060|Burkholderiaceae 28216|Betaproteobacteria Q Gentisate 1,2-dioxygenase - - 1.13.11.4 ko:K00450 ko00350,ko01100,ko01120,map00350,map01100,map01120 - R02656 RC00764 ko00000,ko00001,ko01000 - - - Cupin_2 CMS1_k127_2136392_1 1231391.AMZF01000014_gene2316 1.401e-177 579.0 COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,2VHUG@28216|Betaproteobacteria,3T1N0@506|Alcaligenaceae 28216|Betaproteobacteria S Transporter - - - - - - - - - - - - DctM CMS1_k127_2136392_13 1231391.AMZF01000014_gene2317 2.037e-56 211.0 COG2358@1|root,COG2358@2|Bacteria,1R8QD@1224|Proteobacteria 1224|Proteobacteria S TRAP transporter, solute receptor (TAXI family - - - ko:K07080 - - - - ko00000 - - - NMT1_3 CMS1_k127_2136392_11 1038860.AXAP01000089_gene3711 9.625e-74 256.0 COG2267@1|root,COG2267@2|Bacteria,1MX0N@1224|Proteobacteria,2TU74@28211|Alphaproteobacteria,3JVQG@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Alpha/beta hydrolase family - - 3.1.1.24 ko:K01055 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00568 R02991 RC00825 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_1,Abhydrolase_6 CMS1_k127_2136392_10 426117.M446_6336 3.943e-75 271.0 COG0392@1|root,COG0392@2|Bacteria,1RF8R@1224|Proteobacteria,2U9FV@28211|Alphaproteobacteria,1JSV7@119045|Methylobacteriaceae 28211|Alphaproteobacteria S Lysylphosphatidylglycerol synthase TM region - - - - - - - - - - - - LPG_synthase_TM CMS1_k127_2136392_2 65393.PCC7424_4663 7.031e-154 494.0 COG0535@1|root,COG0535@2|Bacteria,1G4VB@1117|Cyanobacteria,3KJ21@43988|Cyanothece 1117|Cyanobacteria S PFAM Radical SAM domain protein - - - - - - - - - - - - Fer4_12,Radical_SAM,SPASM CMS1_k127_2136392_5 1231391.AMZF01000010_gene1645 1.007e-113 381.0 COG1960@1|root,COG1960@2|Bacteria,1MXMQ@1224|Proteobacteria,2VJZ7@28216|Betaproteobacteria,3T4QU@506|Alcaligenaceae 28216|Betaproteobacteria I Acyl-CoA dehydrogenase, C-terminal domain - - 1.14.14.12,1.14.14.27 ko:K16047,ko:K20942 ko00362,ko00984,ko01100,ko01120,map00362,map00984,map01100,map01120 - R09819,R11348 RC00046,RC00236 ko00000,ko00001,ko01000 - - - Acyl-CoA_dh_2,Acyl-CoA_dh_N CMS1_k127_2136392_17 1131814.JAFO01000001_gene4140 2.986e-20 95.0 COG2350@1|root,COG2350@2|Bacteria,1RH9Y@1224|Proteobacteria,2V6NU@28211|Alphaproteobacteria,3F1QH@335928|Xanthobacteraceae 28211|Alphaproteobacteria S YCII-related domain - - - ko:K09780 - - - - ko00000 - - - YCII CMS1_k127_2136392_0 1304877.KI519399_gene3949 2.278e-181 574.0 COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,2TSXM@28211|Alphaproteobacteria,3JUNR@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria CE Isocitrate/isopropylmalate dehydrogenase MA20_17220 GO:0006082,GO:0006575,GO:0006732,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016053,GO:0019297,GO:0019298,GO:0019752,GO:0032787,GO:0042398,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh,MoCF_biosynth CMS1_k127_2136392_8 670292.JH26_20915 1.373e-87 300.0 COG3622@1|root,COG3622@2|Bacteria,1MV53@1224|Proteobacteria,2TSVI@28211|Alphaproteobacteria,1JS4Y@119045|Methylobacteriaceae 28211|Alphaproteobacteria G Belongs to the hyi family - - 5.3.1.22,5.3.1.35 ko:K01816,ko:K22131 ko00630,ko01100,map00630,map01100 - R01394 RC00511 ko00000,ko00001,ko01000 - - - AP_endonuc_2 CMS1_k127_2136392_12 113395.AXAI01000001_gene2954 8.779e-60 212.0 28KZ2@1|root,2ZAEF@2|Bacteria,1RAF2@1224|Proteobacteria,2U3QP@28211|Alphaproteobacteria,3JY2Z@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_2136392_7 883078.HMPREF9695_00258 4.323e-92 311.0 COG1409@1|root,COG1409@2|Bacteria,1MXD6@1224|Proteobacteria,2TSJ4@28211|Alphaproteobacteria,3JSN9@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Calcineurin-like phosphoesterase superfamily domain - - - - - - - - - - - - Metallophos CMS1_k127_2136392_18 883080.HMPREF9697_01578 1.244e-08 55.0 COG1633@1|root,COG1633@2|Bacteria,1MUET@1224|Proteobacteria,2TQMZ@28211|Alphaproteobacteria,3JR4J@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Rubrerythrin - - - - - - - - - - - - Rubrerythrin CMS1_k127_2138709_1 1297865.APJD01000054_gene2623 3.579e-75 256.0 COG1319@1|root,COG1319@2|Bacteria,1MUDB@1224|Proteobacteria,2TTJF@28211|Alphaproteobacteria,3JR5X@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C CO dehydrogenase flavoprotein C-terminal domain coxM - 1.2.5.3 ko:K03519 - - R11168 RC02800 ko00000,ko01000 - - - CO_deh_flav_C,FAD_binding_5 CMS1_k127_2138709_0 1297865.APJD01000054_gene2624 4.714e-78 263.0 COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,2U5BM@28211|Alphaproteobacteria,3JTFS@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C [2Fe-2S] binding domain coxS - 1.2.5.3 ko:K03518 - - R11168 RC02800 ko00000,ko01000 - - - Fer2,Fer2_2 CMS1_k127_2138709_2 666509.RCA23_c11300 8.757e-66 228.0 COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TQMW@28211|Alphaproteobacteria 28211|Alphaproteobacteria C COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs coxL - 1.2.5.3 ko:K03520 - - R11168 RC02800 ko00000,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 CMS1_k127_2139924_0 639283.Snov_0680 4.288e-155 498.0 COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,2TQNW@28211|Alphaproteobacteria,3EYAT@335928|Xanthobacteraceae 28211|Alphaproteobacteria C FMN-dependent alpha-hydroxy acid dehydrogenase lldD - 1.1.2.3 ko:K00101 ko00620,ko01100,map00620,map01100 - R00196 RC00044 ko00000,ko00001,ko01000 - - - FMN_dh CMS1_k127_2139924_2 1187851.A33M_2019 1.1e-110 364.0 COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,2TSUR@28211|Alphaproteobacteria,3FDCW@34008|Rhodovulum 28211|Alphaproteobacteria V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin uppP - 3.6.1.27 ko:K06153 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - BacA CMS1_k127_2139924_1 1297863.APJF01000006_gene1160 8.385e-136 439.0 COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,2TR5E@28211|Alphaproteobacteria,3JSKT@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) queG GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 ko:K18979 - - - - ko00000,ko01000,ko03016 - - - DUF1730,Fer4_16,HEAT_2 CMS1_k127_2156022_2 709797.CSIRO_1361 1.692e-61 212.0 COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,2TSS5@28211|Alphaproteobacteria,3JQSH@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria D nucleoside-triphosphate diphosphatase activity maf - - ko:K06287 - - - - ko00000 - - - Maf CMS1_k127_2156022_0 1411123.JQNH01000001_gene1970 8.754e-224 703.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria 28211|Alphaproteobacteria IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C CMS1_k127_2156022_1 1120983.KB894571_gene2128 3.11e-89 298.0 COG3384@1|root,COG3384@2|Bacteria,1R3TY@1224|Proteobacteria,2VGIR@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Catalytic LigB subunit of aromatic ring-opening dioxygenase - - - - - - - - - - - - LigB CMS1_k127_2160562_3 384765.SIAM614_04060 5.748e-71 244.0 COG2223@1|root,COG2223@2|Bacteria,1QVKP@1224|Proteobacteria,2TRVV@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Major facilitator superfamily - - - - - - - - - - - - MFS_1 CMS1_k127_2160562_0 944435.AXAJ01000001_gene660 6.274e-191 612.0 COG1053@1|root,COG1053@2|Bacteria,1MURY@1224|Proteobacteria,2VJYH@28216|Betaproteobacteria,1K1DW@119060|Burkholderiaceae 28216|Betaproteobacteria C PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein - - - - - - - - - - - - FAD_binding_2 CMS1_k127_2160562_4 1304878.AUGD01000002_gene1439 4.168e-50 182.0 COG1285@1|root,COG1285@2|Bacteria,1MURJ@1224|Proteobacteria,2U5UM@28211|Alphaproteobacteria,3JYFF@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S MgtC family - - - ko:K07507 - - - - ko00000,ko02000 9.B.20 - - MgtC CMS1_k127_2160562_1 1101190.ARWB01000001_gene1937 3.795e-138 451.0 COG1231@1|root,COG1231@2|Bacteria,1MUPQ@1224|Proteobacteria,2TRVT@28211|Alphaproteobacteria 28211|Alphaproteobacteria E amine oxidase - - 1.4.3.4 ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 M00135 R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354 RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713 ko00000,ko00001,ko00002,ko01000 - - - Amino_oxidase CMS1_k127_2160562_7 316056.RPC_2864 0.0003284 46.0 2CHK4@1|root,2ZDQM@2|Bacteria,1N1BQ@1224|Proteobacteria,2UCMX@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_2160562_6 1461693.ATO10_03500 2.12e-25 106.0 COG0607@1|root,32YCZ@2|Bacteria,1N6NN@1224|Proteobacteria,2UFC1@28211|Alphaproteobacteria 28211|Alphaproteobacteria P sulfurtransferase - - - - - - - - - - - - DUF2892 CMS1_k127_2160562_2 66429.JOFL01000028_gene5062 1.655e-86 301.0 COG2141@1|root,COG2141@2|Bacteria 2|Bacteria C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - - - - - - - - - - Bac_luciferase CMS1_k127_2160562_5 1120934.KB894419_gene2119 1.391e-32 131.0 COG2936@1|root,COG2936@2|Bacteria,2GKZH@201174|Actinobacteria,4E0CY@85010|Pseudonocardiales 201174|Actinobacteria S X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain - - - ko:K06978 - - - - ko00000 - - - PepX_C,Peptidase_S15 CMS1_k127_2171577_0 1282876.BAOK01000001_gene2124 0.0 1288.0 COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,2TQJ7@28211|Alphaproteobacteria,4BPKE@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria C Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity katG - 1.11.1.21 ko:K03782 ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110 - R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906 RC00034,RC00213,RC00767,RC02141 ko00000,ko00001,ko01000 - - - peroxidase CMS1_k127_2171577_1 83219.PM02_16260 9.448e-38 146.0 2C8CV@1|root,2Z8NV@2|Bacteria,1MWPM@1224|Proteobacteria,2TU5G@28211|Alphaproteobacteria,3ZVU7@60136|Sulfitobacter 28211|Alphaproteobacteria S Protein of unknown function (DUF3095) MA20_06625 - - - - - - - - - - - DUF3095 CMS1_k127_217637_5 1187851.A33M_0325 3.673e-52 188.0 COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,2TSEY@28211|Alphaproteobacteria,3FCVC@34008|Rhodovulum 28211|Alphaproteobacteria M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) murG - 2.4.1.227 ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 - R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011 - GT28 - Glyco_tran_28_C,Glyco_transf_28 CMS1_k127_217637_4 1197906.CAJQ02000023_gene2431 5.757e-170 541.0 COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,2TQSA@28211|Alphaproteobacteria,3JV9H@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria D Belongs to the SEDS family ftsW - - ko:K03588 ko04112,map04112 - - - ko00000,ko00001,ko02000,ko03036 2.A.103.1 - - FTSW_RODA_SPOVE CMS1_k127_217637_6 1230476.C207_05247 1.899e-45 167.0 COG2827@1|root,COG2827@2|Bacteria,1MZME@1224|Proteobacteria,2UCNX@28211|Alphaproteobacteria,3JZEM@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L GIY-YIG type nucleases (URI domain) - - - ko:K07461 - - - - ko00000 - - - GIY-YIG CMS1_k127_217637_1 1429916.X566_15200 2.993e-188 598.0 COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,2TTE8@28211|Alphaproteobacteria,3JSWK@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD - 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase_C,Mur_ligase_M CMS1_k127_217637_2 323097.Nham_1276 3.937e-185 591.0 COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,2TRUG@28211|Alphaproteobacteria,3JSUT@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan mraY - 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 - R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 - - Glycos_transf_4,MraY_sig1 CMS1_k127_217637_3 709797.CSIRO_4077 4.702e-185 594.0 COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,2TR0Q@28211|Alphaproteobacteria,3JT30@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF - 6.3.2.10,6.3.2.13 ko:K01928,ko:K01929,ko:K15792 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R02788,R04573,R04617 RC00064,RC00090,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M CMS1_k127_217637_0 883080.HMPREF9697_03857 5.704e-193 614.0 COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,2TVXI@28211|Alphaproteobacteria,3JS79@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE - 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M CMS1_k127_2189300_4 1131814.JAFO01000001_gene2851 1.857e-18 86.0 COG0834@1|root,COG0834@2|Bacteria,1MV5D@1224|Proteobacteria,2TTXX@28211|Alphaproteobacteria,3F1W5@335928|Xanthobacteraceae 28211|Alphaproteobacteria ET Bacterial periplasmic substrate-binding proteins gltI - - ko:K02030,ko:K10001 ko02010,ko02020,map02010,map02020 M00230,M00236 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.19,3.A.1.3.4 - - SBP_bac_3 CMS1_k127_2189300_1 1187851.A33M_2414 5.365e-221 701.0 COG0028@1|root,COG0028@2|Bacteria,1MWVW@1224|Proteobacteria,2TTH5@28211|Alphaproteobacteria 28211|Alphaproteobacteria EH Belongs to the TPP enzyme family ilvB - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N CMS1_k127_2189300_3 1187851.A33M_2409 4.611e-185 588.0 COG0349@1|root,COG0349@2|Bacteria,1MURV@1224|Proteobacteria,2TSQM@28211|Alphaproteobacteria,3FCTE@34008|Rhodovulum 28211|Alphaproteobacteria J Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides rnd - 3.1.13.5 ko:K03684 - - - - ko00000,ko01000,ko03016 - - - DNA_pol_A_exo1,HRDC CMS1_k127_2189300_2 1187851.A33M_2408 1.085e-217 687.0 COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,2TR1W@28211|Alphaproteobacteria,3FCGS@34008|Rhodovulum 28211|Alphaproteobacteria FP Ppx/GppA phosphatase family ppx - 3.6.1.11,3.6.1.40 ko:K01524 ko00230,map00230 - R03409 RC00002 ko00000,ko00001,ko01000 - - - Ppx-GppA CMS1_k127_2189300_0 1187851.A33M_2407 3.028e-279 863.0 COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,2TRBP@28211|Alphaproteobacteria,3FCR7@34008|Rhodovulum 28211|Alphaproteobacteria F Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) ppk - 2.7.4.1 ko:K00937 ko00190,ko03018,map00190,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - PP_kinase,PP_kinase_C,PP_kinase_N CMS1_k127_218955_1 652103.Rpdx1_4283 5.222e-164 523.0 COG0620@1|root,COG0620@2|Bacteria,1MV2Z@1224|Proteobacteria,2TSRH@28211|Alphaproteobacteria,3JTC4@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Cobalamin-independent synthase, Catalytic domain MA20_07800 - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_2 CMS1_k127_218955_5 1043493.BBLU01000008_gene528 4.644e-55 203.0 COG0685@1|root,COG0685@2|Bacteria,2I92A@201174|Actinobacteria 201174|Actinobacteria E Methylenetetrahydrofolate reductase - - 1.5.1.20 ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 M00377 R01224,R07168 RC00081 ko00000,ko00001,ko00002,ko01000 - - - MTHFR CMS1_k127_218955_0 1429916.X566_17250 1.052e-200 634.0 COG0742@1|root,COG0742@2|Bacteria,1MW6A@1224|Proteobacteria,2TQNI@28211|Alphaproteobacteria,3JR22@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L ribosomal rna small subunit methyltransferase MA20_07810 - - - - - - - - - - - - CMS1_k127_218955_8 709797.CSIRO_3986 3.05e-19 89.0 COG3485@1|root,COG3485@2|Bacteria,1MV3B@1224|Proteobacteria,2TTZJ@28211|Alphaproteobacteria,3JSK1@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria Q Dioxygenase pcaG - 1.13.11.3 ko:K00448 ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220 - R01631,R03549 RC00388,RC00953 br01602,ko00000,ko00001,ko01000 - - - Dioxygenase_C CMS1_k127_218955_9 1502851.FG93_02679 7.898e-07 56.0 COG3485@1|root,COG3485@2|Bacteria,1MUYX@1224|Proteobacteria,2TU2C@28211|Alphaproteobacteria,3JT90@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria Q Protocatechuate 3,4-dioxygenase beta subunit N terminal pcaH - 1.13.11.3 ko:K00449 ko00362,ko00624,ko01100,ko01120,ko01220,map00362,map00624,map01100,map01120,map01220 - R01631,R03549 RC00388,RC00953 br01602,ko00000,ko00001,ko01000 - - - Dioxygenase_C,PCDO_beta_N CMS1_k127_218955_2 566466.NOR53_1585 1.553e-136 440.0 COG0673@1|root,COG0673@2|Bacteria,1MXUP@1224|Proteobacteria,1RP9K@1236|Gammaproteobacteria,1J9Q9@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S dehydrogenases and related proteins - - 1.1.1.312 ko:K10219 ko00350,ko00362,ko00627,ko01120,ko01220,map00350,map00362,map00627,map01120,map01220 M00533 R04278,R04279,R04418,R04419 RC00251,RC00254 ko00000,ko00001,ko00002,ko01000 - - - GFO_IDH_MocA,GFO_IDH_MocA_C CMS1_k127_218955_3 1121033.AUCF01000026_gene2985 5.563e-133 432.0 COG3384@1|root,COG3384@2|Bacteria,1MW77@1224|Proteobacteria,2TRP1@28211|Alphaproteobacteria,2JVBN@204441|Rhodospirillales 204441|Rhodospirillales S Catalytic LigB subunit of aromatic ring-opening dioxygenase - - - - - - - - - - - - LigA,LigB CMS1_k127_218955_6 1437824.BN940_08551 3.868e-46 171.0 COG3384@1|root,COG3384@2|Bacteria,1RA8A@1224|Proteobacteria,2VQ2B@28216|Betaproteobacteria,3T7IJ@506|Alcaligenaceae 28216|Betaproteobacteria S Aromatic-ring-opening dioxygenase LigAB, LigA subunit - - 1.13.11.8 ko:K04100 ko00362,ko00624,ko00627,ko01120,map00362,map00624,map00627,map01120 - R01632,R03550,R04280,R09565 RC00233,RC00387,RC00535,RC02567,RC02694 br01602,ko00000,ko00001,ko01000 - - - LigA CMS1_k127_218955_4 1449049.JONW01000005_gene1781 1.798e-59 211.0 COG1720@1|root,COG1720@2|Bacteria,1MUF0@1224|Proteobacteria,2TVD8@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Uncharacterised protein family UPF0066 - - - - - - - - - - - - UPF0066 CMS1_k127_218955_7 314271.RB2654_21003 2.87e-43 159.0 COG3618@1|root,COG3618@2|Bacteria,1N2QM@1224|Proteobacteria,2TTZK@28211|Alphaproteobacteria 28211|Alphaproteobacteria K metal-dependent hydrolase of the TIM-barrel fold ligI - 3.1.1.57 ko:K10221 ko00362,ko00627,ko01120,map00362,map00627,map01120 - R04277 RC03110 ko00000,ko00001,ko01000 - - - Amidohydro_2 CMS1_k127_2193299_0 883078.HMPREF9695_01231 0.0 1009.0 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2TR80@28211|Alphaproteobacteria,3JQNW@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P ATPase, P-type (transporting), HAD superfamily, subfamily IC - - 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,Hydrolase,YHS CMS1_k127_2193299_1 395494.Galf_2723 2.056e-17 87.0 2DY16@1|root,347JT@2|Bacteria,1P2MN@1224|Proteobacteria,2W4PM@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_2196237_2 1121028.ARQE01000013_gene67 8.515e-141 448.0 COG0538@1|root,COG0538@2|Bacteria,1MUIB@1224|Proteobacteria,2TQWD@28211|Alphaproteobacteria,2PJIG@255475|Aurantimonadaceae 28211|Alphaproteobacteria C Isocitrate/isopropylmalate dehydrogenase icd - 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh CMS1_k127_2196237_3 1187851.A33M_1140 1.835e-140 456.0 COG0664@1|root,COG0664@2|Bacteria,1QU34@1224|Proteobacteria,2TVH6@28211|Alphaproteobacteria 28211|Alphaproteobacteria T COG1226 Kef-type K transport systems - GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0042802,GO:0044464,GO:0071944 - ko:K10716 - - - - ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 - - Ion_trans,Ion_trans_2,cNMP_binding CMS1_k127_2196237_1 631454.N177_0579 1.987e-166 542.0 COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,2TRC5@28211|Alphaproteobacteria,1JNPE@119043|Rhodobiaceae 28211|Alphaproteobacteria P Sodium/hydrogen exchanger family kefB - - ko:K03455 - - - - ko00000 2.A.37 - - Na_H_Exchanger,TrkA_N CMS1_k127_2196237_0 1429916.X566_24235 2.561e-219 688.0 COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,2TQV4@28211|Alphaproteobacteria,3JS26@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD CMS1_k127_2210980_1 1123392.AQWL01000005_gene3070 1.522e-78 262.0 COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,2VHBC@28216|Betaproteobacteria,1KRX6@119069|Hydrogenophilales 119069|Hydrogenophilales S Phosphotransferase enzyme family - - 2.7.1.221 ko:K07102 ko00520,ko01100,map00520,map01100 - R08968,R11024 RC00002,RC00078 ko00000,ko00001,ko01000 - - - APH CMS1_k127_2210980_0 1123393.KB891316_gene1658 2.08e-122 396.0 COG1208@1|root,COG1208@2|Bacteria,1R9ZD@1224|Proteobacteria,2VJUN@28216|Betaproteobacteria,1KSTP@119069|Hydrogenophilales 119069|Hydrogenophilales JM Nucleotidyl transferase - - - - - - - - - - - - NTP_transferase CMS1_k127_221494_2 76114.ebA5393 5.219e-146 467.0 COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,2VMWP@28216|Betaproteobacteria,2KVYZ@206389|Rhodocyclales 206389|Rhodocyclales C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family padB - 1.17.5.1,3.1.2.25 ko:K18361 ko00360,map00360 - R07222,R07294 RC00004,RC01844,RC01903 ko00000,ko00001,ko01000 - - - Molybdopterin,Molydop_binding CMS1_k127_221494_6 1380394.JADL01000002_gene1592 1.591e-36 143.0 COG5496@1|root,COG5496@2|Bacteria,1RKFT@1224|Proteobacteria,2U5DE@28211|Alphaproteobacteria,2JUEU@204441|Rhodospirillales 204441|Rhodospirillales S Thioesterase - - - - - - - - - - - - - CMS1_k127_221494_7 1245469.S58_03710 7.939e-15 81.0 2EHR2@1|root,33BGW@2|Bacteria,1RAEI@1224|Proteobacteria,2U6T1@28211|Alphaproteobacteria,3JYHP@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - MA20_43630 - - - - - - - - - - - - CMS1_k127_221494_5 1380355.JNIJ01000001_gene3891 1.607e-98 332.0 COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,2TQK1@28211|Alphaproteobacteria,3JVWU@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Branched-chain amino acid ATP-binding cassette transporter - - - ko:K01995 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C CMS1_k127_221494_4 1411123.JQNH01000001_gene1842 8.442e-120 392.0 COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,2TSJQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Belongs to the binding-protein-dependent transport system permease family - - - ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 CMS1_k127_221494_3 1120983.KB894570_gene1259 2.347e-131 424.0 COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,2TSDS@28211|Alphaproteobacteria,1JP9F@119043|Rhodobiaceae 28211|Alphaproteobacteria E Branched-chain amino acid transport system / permease component - - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 CMS1_k127_221494_1 1120956.JHZK01000027_gene1168 9.393e-188 592.0 COG0683@1|root,COG0683@2|Bacteria,1MXR4@1224|Proteobacteria,2TU0F@28211|Alphaproteobacteria,1JPS1@119043|Rhodobiaceae 28211|Alphaproteobacteria E Receptor family ligand binding region - - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 CMS1_k127_221494_0 1244869.H261_05239 9.285e-222 692.0 COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,2VF1V@28211|Alphaproteobacteria 28211|Alphaproteobacteria C COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing - - - - - - - - - - - - FAD_binding_6,Fer2,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NAD_binding_1 CMS1_k127_2264922_0 570952.ATVH01000015_gene1382 2.344e-119 396.0 COG3039@1|root,COG3039@2|Bacteria,1MVDK@1224|Proteobacteria,2TS7B@28211|Alphaproteobacteria,2JQR2@204441|Rhodospirillales 204441|Rhodospirillales L Transposase - - - - - - - - - - - - DDE_Tnp_1,DUF772 CMS1_k127_2264922_1 1207063.P24_15289 2.791e-51 184.0 COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,2TR2H@28211|Alphaproteobacteria,2JPMN@204441|Rhodospirillales 204441|Rhodospirillales L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF CMS1_k127_2279729_0 1038867.AXAY01000047_gene5909 1.276e-227 718.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2TQRZ@28211|Alphaproteobacteria,3JS3I@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter yheS GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K06158 - - - - ko00000,ko03012 - - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn CMS1_k127_2279729_2 1336243.JAEA01000003_gene2483 5.174e-69 239.0 COG2318@1|root,COG2318@2|Bacteria,1RD3M@1224|Proteobacteria,2U8HG@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein conserved in bacteria dinB - - - - - - - - - - - DinB CMS1_k127_2279729_1 1187851.A33M_2400 5.442e-72 245.0 COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,2U5CS@28211|Alphaproteobacteria,3FD0I@34008|Rhodovulum 28211|Alphaproteobacteria F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate ndk GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 M00049,M00050,M00052,M00053 R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895 RC00002 ko00000,ko00001,ko00002,ko01000,ko04131 - - - NDK CMS1_k127_2286210_0 1120965.AUBV01000001_gene3274 2.778e-97 329.0 COG1048@1|root,COG1048@2|Bacteria,4NDZT@976|Bacteroidetes,47KF9@768503|Cytophagia 976|Bacteroidetes C aconitate hydratase acnA - 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C CMS1_k127_2286210_1 265072.Mfla_2079 5.213e-17 91.0 2DP0A@1|root,3300Q@2|Bacteria,1N78Y@1224|Proteobacteria,2VVZ5@28216|Betaproteobacteria,2KMZB@206350|Nitrosomonadales 206350|Nitrosomonadales S PFAM Sporulation domain protein - - - - - - - - - - - - - CMS1_k127_2286210_2 557598.LHK_03253 3.364e-05 46.0 COG1521@1|root,COG1521@2|Bacteria,1MUYA@1224|Proteobacteria,2VK1G@28216|Betaproteobacteria,2KQC6@206351|Neisseriales 206351|Neisseriales H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis coaX - 2.7.1.33,6.3.4.15 ko:K01947,ko:K03525 ko00770,ko00780,ko01100,map00770,map00780,map01100 M00120 R01074,R02971,R03018,R04391,R05145 RC00002,RC00017,RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko00002,ko01000 - - - BPL_C,BPL_LplA_LipB,Pan_kinase CMS1_k127_2287189_5 883080.HMPREF9697_00628 2.209e-44 173.0 COG0725@1|root,COG0725@2|Bacteria,1PTVK@1224|Proteobacteria,2TU4Y@28211|Alphaproteobacteria,3K6CP@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P Bacterial extracellular solute-binding protein - - - - - - - - - - - - SBP_bac_11 CMS1_k127_2287189_4 1187851.A33M_0877 3.245e-55 197.0 2CN5Z@1|root,32SGB@2|Bacteria,1N1FB@1224|Proteobacteria,2UBV1@28211|Alphaproteobacteria,3FDGF@34008|Rhodovulum 28211|Alphaproteobacteria S Protein of unknown function (DUF2948) MA20_21100 - - - - - - - - - - - DUF2948 CMS1_k127_2287189_0 113395.AXAI01000007_gene1526 1.441e-197 624.0 COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,2TSBN@28211|Alphaproteobacteria,3JR34@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine hisD GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01158,R01163,R03012 RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 - - - Histidinol_dh CMS1_k127_2287189_1 1298867.AUES01000005_gene73 1.569e-71 261.0 COG5328@1|root,COG5328@2|Bacteria,1RA93@1224|Proteobacteria,2U741@28211|Alphaproteobacteria,3JTW9@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Belongs to the UPF0262 family MA20_21090 - - - - - - - - - - - UPF0262 CMS1_k127_2287189_3 1429916.X566_05645 5.723e-61 214.0 COG0394@1|root,COG0394@2|Bacteria,1RANV@1224|Proteobacteria,2U5EE@28211|Alphaproteobacteria,3JU2V@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Low molecular weight phosphotyrosine protein phosphatase MA20_21085 - 1.20.4.1,3.1.3.48 ko:K01104,ko:K03741 - - - - ko00000,ko01000 - - - LMWPc CMS1_k127_2287189_2 709797.CSIRO_1361 4.472e-70 239.0 COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,2TSS5@28211|Alphaproteobacteria,3JQSH@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria D nucleoside-triphosphate diphosphatase activity maf - - ko:K06287 - - - - ko00000 - - - Maf CMS1_k127_2299830_0 1254432.SCE1572_16030 9.1e-112 374.0 COG0620@1|root,COG0620@2|Bacteria,1MV2Z@1224|Proteobacteria,42NPA@68525|delta/epsilon subdivisions,2WT46@28221|Deltaproteobacteria 28221|Deltaproteobacteria E Cobalamin-independent synthase, Catalytic domain - - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_2 CMS1_k127_2299830_1 1380355.JNIJ01000016_gene5750 1.834e-27 116.0 COG0742@1|root,COG0742@2|Bacteria,1MW6A@1224|Proteobacteria,2TQNI@28211|Alphaproteobacteria,3JR22@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L ribosomal rna small subunit methyltransferase MA20_07810 - - - - - - - - - - - - CMS1_k127_2305329_0 1380394.JADL01000002_gene1240 3.31e-96 339.0 COG3712@1|root,COG3712@2|Bacteria,1N941@1224|Proteobacteria,2U29D@28211|Alphaproteobacteria,2JPIM@204441|Rhodospirillales 204441|Rhodospirillales PT iron ion homeostasis - - - - - - - - - - - - - CMS1_k127_2305329_1 1430440.MGMSRv2_4057 5.832e-55 196.0 COG4520@1|root,COG4520@2|Bacteria,1N0YF@1224|Proteobacteria,2UA8D@28211|Alphaproteobacteria,2JSUH@204441|Rhodospirillales 204441|Rhodospirillales M 17 kDa outer membrane surface antigen - - - - - - - - - - - - 17kDa_Anti_2,Rick_17kDa_Anti CMS1_k127_2305329_8 1122612.AUBA01000002_gene1931 1.633e-08 57.0 COG3385@1|root,COG3385@2|Bacteria,1QURV@1224|Proteobacteria,2TW56@28211|Alphaproteobacteria,2KEB3@204457|Sphingomonadales 204457|Sphingomonadales L Transposase DDE domain group 1 - - - - - - - - - - - - DDE_Tnp_1_4 CMS1_k127_2305329_2 1177928.TH2_01480 7.05e-44 168.0 COG4520@1|root,COG4520@2|Bacteria,1N0YF@1224|Proteobacteria,2UD20@28211|Alphaproteobacteria,2JU71@204441|Rhodospirillales 204441|Rhodospirillales M surface antigen - - - - - - - - - - - - 17kDa_Anti_2,Rick_17kDa_Anti CMS1_k127_2305329_6 1082931.KKY_3060 1.287e-09 59.0 COG3293@1|root,COG3293@2|Bacteria,1QXE6@1224|Proteobacteria,2TX8K@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Transposase DDE domain - - - - - - - - - - - - DDE_Tnp_1,DDE_Tnp_1_2 CMS1_k127_2305329_7 596153.Alide_3006 9.078e-09 57.0 COG3385@1|root,COG3385@2|Bacteria,1RGQ2@1224|Proteobacteria,2WHJZ@28216|Betaproteobacteria,4AK3U@80864|Comamonadaceae 28216|Betaproteobacteria L DDE superfamily endonuclease - - - - - - - - - - - - DDE_Tnp_1,DDE_Tnp_1_2 CMS1_k127_2305329_5 13689.BV96_01649 2.002e-14 74.0 COG3293@1|root,COG3293@2|Bacteria,1REVC@1224|Proteobacteria,2U6ZB@28211|Alphaproteobacteria,2KCRY@204457|Sphingomonadales 204457|Sphingomonadales L Putative transposase of IS4/5 family (DUF4096) - - - - - - - - - - - - DUF4096 CMS1_k127_2305329_3 13689.BV96_01649 3.433e-26 108.0 COG3293@1|root,COG3293@2|Bacteria,1REVC@1224|Proteobacteria,2U6ZB@28211|Alphaproteobacteria,2KCRY@204457|Sphingomonadales 204457|Sphingomonadales L Putative transposase of IS4/5 family (DUF4096) - - - - - - - - - - - - DUF4096 CMS1_k127_2305329_4 318161.Sden_1471 1.304e-14 79.0 293WK@1|root,2ZRBR@2|Bacteria,1PBHQ@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - CMS1_k127_2305329_9 204773.HEAR0939 3.186e-05 46.0 2E4YG@1|root,32ZSB@2|Bacteria,1N74T@1224|Proteobacteria,2VVYY@28216|Betaproteobacteria,4756X@75682|Oxalobacteraceae 28216|Betaproteobacteria S Protein of unknown function (DUF3309) - - - - - - - - - - - - DUF3309 CMS1_k127_232677_4 1187851.A33M_2431 7.841e-31 130.0 COG0726@1|root,COG0726@2|Bacteria,1MVKH@1224|Proteobacteria,2TTEI@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Polysaccharide deacetylase - - - - - - - - - - - - Polysacc_deac_1 CMS1_k127_232677_2 316055.RPE_2846 5.708e-83 290.0 COG5653@1|root,COG5653@2|Bacteria,1MVAR@1224|Proteobacteria,2TTKY@28211|Alphaproteobacteria,3JRH4@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_6 CMS1_k127_232677_1 316056.RPC_2684 9.881e-180 587.0 COG3206@1|root,COG3206@2|Bacteria,1RK0N@1224|Proteobacteria,2TSFQ@28211|Alphaproteobacteria,3JS8J@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Chain length determinant protein - - - - - - - - - - - - GNVR,Wzz CMS1_k127_232677_0 443598.AUFA01000003_gene1988 1.56e-204 649.0 COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,2TRZA@28211|Alphaproteobacteria,3JSJ2@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M CoA-binding domain wcaJ - - ko:K03606,ko:K20997 ko02025,ko05111,map02025,map05111 - - - ko00000,ko00001 - - - Bac_transf,CoA_binding_3 CMS1_k127_232677_3 1502851.FG93_00773 2.188e-74 281.0 COG3307@1|root,COG3307@2|Bacteria,1MWJM@1224|Proteobacteria,2TRG6@28211|Alphaproteobacteria,3JUWK@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M -O-antigen MA20_36890 - - - - - - - - - - - Wzy_C CMS1_k127_2327577_1 716928.AJQT01000068_gene3393 8.172e-222 694.0 28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,2TSGX@28211|Alphaproteobacteria,4BCDP@82115|Rhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF3604) - - - - - - - - - - - - DUF3604 CMS1_k127_2327577_0 1123242.JH636434_gene4533 9.514e-299 924.0 COG3119@1|root,COG3119@2|Bacteria,2IXNZ@203682|Planctomycetes 203682|Planctomycetes P PFAM sulfatase - - 3.1.6.1 ko:K01130 ko00140,ko00600,map00140,map00600 - R03980,R04856 RC00128,RC00231 ko00000,ko00001,ko01000 - - - Sulfatase,Sulfatase_C CMS1_k127_2327577_2 1429916.X566_06255 3.608e-13 69.0 COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,2TRFZ@28211|Alphaproteobacteria,3JRGR@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Transcriptional regulatory protein, C terminal phoB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K07657 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C CMS1_k127_2343737_7 224911.27353463 1.079e-33 132.0 COG3293@1|root,COG3293@2|Bacteria,1P5HD@1224|Proteobacteria,2TUQI@28211|Alphaproteobacteria,3JZFP@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L Transposase DDE domain - - - - - - - - - - - - DDE_Tnp_1_2,DUF4096 CMS1_k127_2343737_8 670307.HYPDE_37393 1.433e-05 52.0 COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,2TRPB@28211|Alphaproteobacteria,3N671@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria H DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX - 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3,DUF3646 CMS1_k127_2343737_0 883080.HMPREF9697_03249 6.265e-236 746.0 COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,2TRPB@28211|Alphaproteobacteria,3JS32@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX - 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3,DUF3646 CMS1_k127_2343737_6 876269.ARWA01000001_gene814 1.182e-38 146.0 COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,2UBQB@28211|Alphaproteobacteria,3NBEP@45404|Beijerinckiaceae 28211|Alphaproteobacteria L Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection ybaB - - ko:K09747 - - - - ko00000 - - - YbaB_DNA_bd CMS1_k127_2343737_4 316055.RPE_4811 8.104e-109 354.0 COG0353@1|root,COG0353@2|Bacteria,1MV9Q@1224|Proteobacteria,2TRZM@28211|Alphaproteobacteria,3JSDW@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO recR - - ko:K06187 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecR,Toprim_4 CMS1_k127_2343737_1 1380355.JNIJ01000022_gene3553 2.449e-188 606.0 COG0633@1|root,COG2114@1|root,COG0633@2|Bacteria,COG2114@2|Bacteria,1N5XC@1224|Proteobacteria,2TRGX@28211|Alphaproteobacteria,3JQU2@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria CT Adenylyl- / guanylyl cyclase, catalytic domain cyaA - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - Fer2,Guanylate_cyc CMS1_k127_2343737_2 639283.Snov_4377 5.37e-186 592.0 COG2211@1|root,COG2211@2|Bacteria,1QTSE@1224|Proteobacteria,2TWGV@28211|Alphaproteobacteria,3EZ47@335928|Xanthobacteraceae 28211|Alphaproteobacteria G Acetyl-coenzyme A transporter 1 ampG - - ko:K08218 ko01501,map01501 M00628 - - ko00000,ko00001,ko00002,ko02000 2.A.1.25 - - Acatn,MFS_1 CMS1_k127_2343737_3 666684.AfiDRAFT_0928 9.251e-111 369.0 COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,2TTX6@28211|Alphaproteobacteria,3JTBH@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S RmuC family rmuC - - ko:K09760 - - - - ko00000 - - - RmuC CMS1_k127_2343737_5 1510531.JQJJ01000009_gene439 1.044e-72 249.0 COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,2U797@28211|Alphaproteobacteria,3JTAJ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions def GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.31,3.5.1.88 ko:K01450,ko:K01462 ko00270,ko00630,map00270,map00630 - R00653 RC00165,RC00323 ko00000,ko00001,ko01000 - - - Pep_deformylase CMS1_k127_2348540_0 105559.Nwat_0725 9.256e-104 347.0 COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,1RN0F@1236|Gammaproteobacteria,1WWCF@135613|Chromatiales 135613|Chromatiales T Histidine kinase - - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - DUF3329,HATPase_c,HisKA,PAS,PAS_8 CMS1_k127_2348540_1 1033802.SSPSH_000086 2.357e-36 141.0 COG0640@1|root,COG0640@2|Bacteria,1MZT1@1224|Proteobacteria,1SAI5@1236|Gammaproteobacteria 1236|Gammaproteobacteria K transcriptional regulator arsR - - ko:K03892 - - - - ko00000,ko03000 - - - HTH_5,LMWPc CMS1_k127_2351828_2 399739.Pmen_3614 4.746e-17 84.0 COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,1RM8G@1236|Gammaproteobacteria,1YCV3@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives folP GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042221,GO:0042364,GO:0042398,GO:0042493,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046655,GO:0046656,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15 ko:K00796 ko00790,ko01100,map00790,map01100 M00126,M00841 R03066,R03067 RC00121,RC00842 ko00000,ko00001,ko00002,ko01000 - - iECO103_1326.ECO103_3924,iPC815.YPO3501 Pterin_bind CMS1_k127_2351828_0 1038922.PflQ2_0715 0.0 1022.0 COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,1RME8@1236|Gammaproteobacteria,1YMRK@136843|Pseudomonas fluorescens group 1236|Gammaproteobacteria O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins ftsH GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41 CMS1_k127_2351828_1 1390370.O203_13465 2.19e-123 396.0 COG0293@1|root,COG0293@2|Bacteria,1MW1C@1224|Proteobacteria,1RN5M@1236|Gammaproteobacteria,1YF14@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria J Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit ftsJ GO:0000027,GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008650,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.166 ko:K02427 - - - - ko00000,ko01000,ko03009 - - - FtsJ CMS1_k127_2351828_3 160488.PP_4720 2.976e-11 66.0 COG1534@1|root,COG1534@2|Bacteria,1N8K5@1224|Proteobacteria,1S67P@1236|Gammaproteobacteria,1YVKI@136845|Pseudomonas putida group 1236|Gammaproteobacteria J CRS1 / YhbY (CRM) domain IV02_28930 - - ko:K07574 - - - - ko00000,ko03009 - - - CRS1_YhbY CMS1_k127_2374544_16 1297569.MESS2_1190054 2.731e-24 104.0 COG0673@1|root,COG0673@2|Bacteria,1MU8F@1224|Proteobacteria,2U12U@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C CMS1_k127_2374544_6 1187851.A33M_1549 8.915e-175 561.0 COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,2TT78@28211|Alphaproteobacteria,3FDGI@34008|Rhodovulum 28211|Alphaproteobacteria U Dimerisation domain of Zinc Transporter MA20_15190 - - ko:K13283 - - - - ko00000,ko02000 2.A.4.7.1 - - Cation_efflux,ZT_dimer CMS1_k127_2374544_7 136993.KB900626_gene2801 1.143e-158 505.0 COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,2TTI9@28211|Alphaproteobacteria,36ZWP@31993|Methylocystaceae 28211|Alphaproteobacteria S Alcohol dehydrogenase GroES-like domain - - 1.1.1.1 ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N CMS1_k127_2374544_1 1120792.JAFV01000001_gene1619 0.0 1077.0 COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,2TRUM@28211|Alphaproteobacteria,36XNP@31993|Methylocystaceae 28211|Alphaproteobacteria E Domain of unknown function (DUF3458_C) ARM repeats pepN GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0016020,GO:0016787,GO:0019538,GO:0033218,GO:0042277,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - DUF3458,DUF3458_C,Peptidase_M1 CMS1_k127_2374544_3 1187851.A33M_0444 1.066e-292 917.0 COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2TZRH@28211|Alphaproteobacteria,3FDTS@34008|Rhodovulum 1224|Proteobacteria T His Kinase A (phosphoacceptor) domain pleC - 2.7.13.3 ko:K07716 ko02020,ko04112,map02020,map04112 M00511 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_3,PAS_7 CMS1_k127_2374544_8 1380391.JIAS01000011_gene5498 3.199e-147 472.0 COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2TUWV@28211|Alphaproteobacteria,2JQWC@204441|Rhodospirillales 204441|Rhodospirillales E Pyridoxal-phosphate dependent enzyme - - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP CMS1_k127_2374544_0 323098.Nwi_1199 0.0 1114.0 COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,2TRY7@28211|Alphaproteobacteria,3JR47@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell glnE GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0031323,GO:0033238,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0080090 2.7.7.42,2.7.7.89 ko:K00982 - - - - ko00000,ko01000 - - - GlnD_UR_UTase,GlnE CMS1_k127_2374544_4 1187851.A33M_0435 1.872e-195 619.0 COG0642@1|root,COG0642@2|Bacteria,1QTVA@1224|Proteobacteria,2U5EI@28211|Alphaproteobacteria 28211|Alphaproteobacteria T Histidine kinase MA20_15235 - - - - - - - - - - - HAMP,HATPase_c,HisKA CMS1_k127_2374544_10 1041147.AUFB01000002_gene3258 6.964e-108 354.0 COG0745@1|root,COG0745@2|Bacteria,1MU67@1224|Proteobacteria,2TRTZ@28211|Alphaproteobacteria,4B8KP@82115|Rhizobiaceae 28211|Alphaproteobacteria T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain ragA GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009889,GO:0009893,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010556,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0023052,GO:0031323,GO:0031326,GO:0035556,GO:0042221,GO:0042802,GO:0046688,GO:0048518,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - ko:K02483 - - - - ko00000,ko02022 - - - Response_reg,Trans_reg_C CMS1_k127_2374544_5 172088.AUGA01000026_gene296 4.302e-192 613.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2TQPZ@28211|Alphaproteobacteria,3JQQI@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O Belongs to the peptidase S1C family MA20_15480 - 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 CMS1_k127_2374544_15 114615.BRADO2735 3.132e-48 178.0 COG3088@1|root,COG3088@2|Bacteria,1MZZ5@1224|Proteobacteria,2U96P@28211|Alphaproteobacteria,3JYWC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O subunit of a heme lyase cycL - - ko:K02200 - - - - ko00000 - - - CcmH CMS1_k127_2374544_2 316057.RPD_2003 1.534e-306 951.0 COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,2TRNG@28211|Alphaproteobacteria,3JRX0@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O Cytochrome c-type biogenesis protein ccmF - - ko:K02198 - - - - ko00000,ko02000 9.B.14.1 - - CcmF_C,Cytochrom_C_asm CMS1_k127_2374544_14 1380355.JNIJ01000033_gene4221 1.673e-58 207.0 COG2332@1|root,COG2332@2|Bacteria,1RHN5@1224|Proteobacteria,2U99J@28211|Alphaproteobacteria,3JYFM@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH ccmE GO:0003674,GO:0003824,GO:0008150,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840 - ko:K02197 - - - - ko00000 - - - CcmE CMS1_k127_2374544_9 398525.KB900701_gene3842 8.844e-112 372.0 COG4235@1|root,COG4235@2|Bacteria,1MY4J@1224|Proteobacteria,2TSI7@28211|Alphaproteobacteria,3JT3X@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O Cytochrome c-type biogenesis protein cycH - - ko:K02200 - - - - ko00000 - - - TPR_16,TPR_19 CMS1_k127_2374544_11 504832.OCAR_6577 2.051e-86 303.0 28K9G@1|root,2Z9X1@2|Bacteria,1NEMY@1224|Proteobacteria,2U0J7@28211|Alphaproteobacteria,3JSTQ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - MA20_15515 - - - - - - - - - - - - CMS1_k127_2374544_13 1187851.A33M_0420 9.742e-65 230.0 COG4520@1|root,COG4520@2|Bacteria,1N0YF@1224|Proteobacteria,2UA8D@28211|Alphaproteobacteria 28211|Alphaproteobacteria M surface antigen omp - - - - - - - - - - - 17kDa_Anti_2,Gly-zipper_Omp,Rick_17kDa_Anti CMS1_k127_2374544_12 1218076.BAYB01000053_gene6082 7.696e-84 285.0 COG0778@1|root,COG0778@2|Bacteria,1PG8V@1224|Proteobacteria,2VKIZ@28216|Betaproteobacteria,1K24T@119060|Burkholderiaceae 28216|Betaproteobacteria C nitroreductase - - - - - - - - - - - - Nitroreductase CMS1_k127_237619_2 1126627.BAWE01000002_gene383 1.912e-50 188.0 COG0701@1|root,COG0701@2|Bacteria,1PS2M@1224|Proteobacteria,2TSWG@28211|Alphaproteobacteria,3JUKF@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Predicted permease MA20_06590 - - - - - - - - - - - - CMS1_k127_237619_3 1297863.APJF01000010_gene3315 3.393e-49 183.0 COG0701@1|root,COG0701@2|Bacteria,1P74D@1224|Proteobacteria,2TR7H@28211|Alphaproteobacteria,3JSBG@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Predicted permease MA20_06595 - - - - - - - - - - - ArsP_1 CMS1_k127_237619_0 1211115.ALIQ01000185_gene3124 0.0 1457.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria 28211|Alphaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family ttgE - - ko:K18989 - M00720 - - ko00000,ko00002,ko02000 2.A.6.2.30 - - ACR_tran CMS1_k127_237619_1 1123229.AUBC01000014_gene2891 9.086e-96 326.0 COG0845@1|root,COG0845@2|Bacteria,1NQZ0@1224|Proteobacteria,2U105@28211|Alphaproteobacteria,3JUK0@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Biotin-lipoyl like ragD - - - - - - - - - - - HlyD_D23 CMS1_k127_237619_4 582899.Hden_2913 4.723e-41 159.0 COG1309@1|root,COG1309@2|Bacteria,1RARJ@1224|Proteobacteria,2UAVR@28211|Alphaproteobacteria,3N992@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_C_6,TetR_N CMS1_k127_2389149_2 1121106.JQKB01000013_gene5482 2.311e-110 367.0 COG0477@1|root,COG2814@2|Bacteria,1MX2P@1224|Proteobacteria,2V9TU@28211|Alphaproteobacteria,2JVBG@204441|Rhodospirillales 204441|Rhodospirillales EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 CMS1_k127_2389149_0 443598.AUFA01000001_gene1078 1.286e-141 466.0 2CJVH@1|root,2Z82D@2|Bacteria,1MX2M@1224|Proteobacteria,2TTCY@28211|Alphaproteobacteria,3JSEN@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - MA20_19455 - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - - CMS1_k127_2389149_1 1297865.APJD01000011_gene6577 1.395e-111 366.0 COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,2TY37@28211|Alphaproteobacteria,3JRC1@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria V ATPases associated with a variety of cellular activities MA20_19450 - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran CMS1_k127_2389149_3 935837.JAEK01000016_gene1270 0.0003561 48.0 COG1638@1|root,COG1638@2|Bacteria,1TP3I@1239|Firmicutes,4HD0U@91061|Bacilli,1ZCY6@1386|Bacillus 91061|Bacilli G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - - - - - - - - - - DctP CMS1_k127_2390147_2 388399.SSE37_00950 1.518e-53 200.0 COG2358@1|root,COG2358@2|Bacteria,1R8QD@1224|Proteobacteria,2U7M9@28211|Alphaproteobacteria 28211|Alphaproteobacteria S TRAP transporter solute receptor TAXI family protein - - - - - - - - - - - - NMT1_3 CMS1_k127_2390147_3 883078.HMPREF9695_00199 9.178e-17 84.0 2EPTB@1|root,33HDV@2|Bacteria,1N08E@1224|Proteobacteria,2UC66@28211|Alphaproteobacteria,3K0I8@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_2390147_1 1187851.A33M_0345 2.926e-95 321.0 COG0500@1|root,COG2226@2|Bacteria,1MVIS@1224|Proteobacteria,2TV8R@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q phosphatidylethanolamine N-methyltransferase pmtA - 2.1.1.17,2.1.1.71 ko:K00570 ko00564,ko01100,ko01110,map00564,map01100,map01110 M00091 R01320,R02056,R03424 RC00003,RC00060,RC00181,RC00496 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_11 CMS1_k127_2390147_0 316058.RPB_4116 6.17e-139 447.0 COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,2TQU7@28211|Alphaproteobacteria,3JQMX@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 mnmA - 2.8.1.13 ko:K00566 ko04122,map04122 - R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 - - - tRNA_Me_trans CMS1_k127_2430803_11 1411123.JQNH01000001_gene1483 1.864e-71 245.0 COG1975@1|root,COG1975@2|Bacteria,1MWFN@1224|Proteobacteria,2TS6Z@28211|Alphaproteobacteria 28211|Alphaproteobacteria O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family coxF - - ko:K07402 - - - - ko00000 - - - XdhC_C,XdhC_CoxI CMS1_k127_2430803_10 1125973.JNLC01000001_gene42 3.326e-80 287.0 COG1376@1|root,COG1376@2|Bacteria,1MXZM@1224|Proteobacteria,2TSBH@28211|Alphaproteobacteria,3JU61@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S L,D-transpeptidase catalytic domain MA20_01325 - - - - - - - - - - - YkuD CMS1_k127_2430803_13 176299.Atu5225 2.993e-45 169.0 COG0599@1|root,COG0599@2|Bacteria,1RJU6@1224|Proteobacteria,2U5JQ@28211|Alphaproteobacteria,4BE4F@82115|Rhizobiaceae 28211|Alphaproteobacteria S Carboxymuconolactone decarboxylase family MA20_20490 - 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 - R03470 RC00938 ko00000,ko00001,ko01000 - - - CMD CMS1_k127_2430803_3 296591.Bpro_2199 6.623e-175 560.0 COG0654@1|root,COG0654@2|Bacteria,1MXEW@1224|Proteobacteria,2VIVN@28216|Betaproteobacteria,4AC5F@80864|Comamonadaceae 28216|Betaproteobacteria C PFAM monooxygenase FAD-binding - - 1.14.13.218 ko:K20940 ko00405,ko01130,map00405,map01130 M00835 - - ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 CMS1_k127_2430803_12 648757.Rvan_3453 7.319e-53 192.0 COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,2U5A1@28211|Alphaproteobacteria,3N7C5@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria K TIGRFAM RNA polymerase sigma factor, sigma-70 family sigW - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 CMS1_k127_2430803_15 1131814.JAFO01000001_gene4095 1.826e-12 74.0 2AFC2@1|root,315BK@2|Bacteria,1PVDB@1224|Proteobacteria,2V6TA@28211|Alphaproteobacteria,3F22D@335928|Xanthobacteraceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_2430803_14 438753.AZC_2428 2.553e-21 99.0 COG5612@1|root,COG5612@2|Bacteria,1NMCU@1224|Proteobacteria,2UK1R@28211|Alphaproteobacteria,3F2CN@335928|Xanthobacteraceae 28211|Alphaproteobacteria S Heavy-metal resistance - - - - - - - - - - - - Metal_resist CMS1_k127_2430803_4 196490.AUEZ01000003_gene3815 6.652e-155 512.0 COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,2TSN8@28211|Alphaproteobacteria,3JQRY@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria MU Outer membrane efflux protein MA20_30040 - - - - - - - - - - - OEP CMS1_k127_2430803_7 1429916.X566_20400 2.688e-124 415.0 COG0845@1|root,COG0845@2|Bacteria,1MW65@1224|Proteobacteria,2TSB6@28211|Alphaproteobacteria,3JR4W@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family mdtA - - ko:K07799,ko:K18990 ko02020,map02020 M00648,M00720 - - ko00000,ko00001,ko00002,ko02000 2.A.6.2.30,8.A.1 - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 CMS1_k127_2430803_0 1187851.A33M_0131 0.0 1389.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria 28211|Alphaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family mdtB - - ko:K07788 ko02020,map02020 M00648 - - ko00000,ko00001,ko00002,ko02000 2.A.6.2 - - ACR_tran CMS1_k127_2430803_1 1187851.A33M_0130 0.0 1311.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria 28211|Alphaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family mdtC - - ko:K07789 ko02020,map02020 M00648 - - ko00000,ko00001,ko00002,ko02000 2.A.6.2 - - ACR_tran CMS1_k127_2430803_8 318996.AXAZ01000038_gene1326 3.93e-110 361.0 COG0410@1|root,COG0410@2|Bacteria,1MVYI@1224|Proteobacteria,2TSRT@28211|Alphaproteobacteria,3JR1U@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E ABC transporter MA20_22545 - - ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran CMS1_k127_2430803_9 398525.KB900701_gene2238 2.26e-100 335.0 COG0411@1|root,COG0411@2|Bacteria,1MXHT@1224|Proteobacteria,2TSWS@28211|Alphaproteobacteria,3JT2Q@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Branched-chain amino acid ATP-binding cassette transporter MA20_22550 - - ko:K01995 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C CMS1_k127_2430803_5 196490.AUEZ01000018_gene3427 1.158e-139 454.0 COG4177@1|root,COG4177@2|Bacteria,1MUPI@1224|Proteobacteria,2TSID@28211|Alphaproteobacteria,3JU2M@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Branched-chain amino acid transport system / permease component MA20_22555 - - ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 CMS1_k127_2430803_6 189753.AXAS01000003_gene4800 5.7e-137 446.0 COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,2TSCF@28211|Alphaproteobacteria,3JSV3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Belongs to the binding-protein-dependent transport system permease family MA20_22560 - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 CMS1_k127_2430803_2 1126627.BAWE01000004_gene1737 7.68e-191 602.0 COG0683@1|root,COG0683@2|Bacteria,1MVV2@1224|Proteobacteria,2TRFU@28211|Alphaproteobacteria,3JRAY@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Receptor family ligand binding region MA20_22630 - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 CMS1_k127_246052_1 1110502.TMO_2816 6.069e-97 323.0 COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,2TQY9@28211|Alphaproteobacteria,2JQJ8@204441|Rhodospirillales 204441|Rhodospirillales S transport system, fused permease components - - - - - - - - - - - - DUF3394,DctM CMS1_k127_246052_2 1089552.KI911559_gene1493 2.455e-54 196.0 COG0589@1|root,COG0589@2|Bacteria,1RI97@1224|Proteobacteria,2UABJ@28211|Alphaproteobacteria,2JSV0@204441|Rhodospirillales 204441|Rhodospirillales T COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - - - - - - - - - - Usp CMS1_k127_246052_3 1265505.ATUG01000003_gene860 3.259e-05 46.0 COG0642@1|root,COG2205@2|Bacteria,1R7QH@1224|Proteobacteria,42PSC@68525|delta/epsilon subdivisions,2WKFW@28221|Deltaproteobacteria,2MJNP@213118|Desulfobacterales 28221|Deltaproteobacteria T Histidine kinase-like ATPases - - - - - - - - - - - - HATPase_c CMS1_k127_246052_0 1210884.HG799466_gene12511 8.688e-171 550.0 COG1032@1|root,COG1032@2|Bacteria,2IYYP@203682|Planctomycetes 203682|Planctomycetes C B12 binding domain - - - - - - - - - - - - B12-binding,DUF4070,Radical_SAM CMS1_k127_249313_5 1187851.A33M_1116 1.638e-101 335.0 COG2197@1|root,COG2197@2|Bacteria,1P4TD@1224|Proteobacteria,2U06A@28211|Alphaproteobacteria,3FE8J@34008|Rhodovulum 28211|Alphaproteobacteria K helix_turn_helix, Lux Regulon MA20_19670 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - - - - - - - - - - GerE,Response_reg CMS1_k127_249313_17 1231190.NA8A_21386 6.004e-34 132.0 COG4327@1|root,COG4327@2|Bacteria,1QA0K@1224|Proteobacteria,2VDY4@28211|Alphaproteobacteria,43MG3@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Domain of unknown function (DUF4212) - - - - - - - - - - - - DUF4212 CMS1_k127_249313_0 391937.NA2_13450 5.333e-313 966.0 COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,2TTA4@28211|Alphaproteobacteria,43H7D@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family yjcG - - ko:K14393 - - - - ko00000,ko02000 2.A.21.7 - - DUF4212,SSF CMS1_k127_249313_9 391937.NA2_13455 4.665e-50 180.0 2CXUS@1|root,32T2P@2|Bacteria,1MZIZ@1224|Proteobacteria,2UBZF@28211|Alphaproteobacteria,43PP0@69277|Phyllobacteriaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - YGGT CMS1_k127_249313_8 391937.NA2_13440 2.478e-55 201.0 2E55J@1|root,32ZYF@2|Bacteria,1N9FR@1224|Proteobacteria,2UGVB@28211|Alphaproteobacteria,43P5B@69277|Phyllobacteriaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_249313_20 1380355.JNIJ01000010_gene1502 6.949e-05 51.0 2EIES@1|root,33C66@2|Bacteria,1NK2A@1224|Proteobacteria,2UMNM@28211|Alphaproteobacteria,3K45Z@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_249313_14 1380355.JNIJ01000010_gene1502 1.14e-36 142.0 2EIES@1|root,33C66@2|Bacteria,1NK2A@1224|Proteobacteria,2UMNM@28211|Alphaproteobacteria,3K45Z@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_249313_7 1187851.A33M_1117 1.949e-62 218.0 COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,2U945@28211|Alphaproteobacteria,3FEFX@34008|Rhodovulum 28211|Alphaproteobacteria S Uncharacterised protein family UPF0047 - - - - - - - - - - - - UPF0047 CMS1_k127_249313_19 1125973.JNLC01000010_gene1677 1.652e-06 60.0 2E3E3@1|root,32YD6@2|Bacteria,1N9CW@1224|Proteobacteria,2UH8F@28211|Alphaproteobacteria,3JTZH@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_249313_18 883078.HMPREF9695_04182 4.382e-32 129.0 COG5336@1|root,COG5336@2|Bacteria,1NHIS@1224|Proteobacteria,2UFJJ@28211|Alphaproteobacteria,3JZII@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex atpI - - ko:K02116 - - - - ko00000,ko00194 3.A.2.1 - - ATPase_gene1 CMS1_k127_249313_4 1038859.AXAU01000005_gene5100 2.401e-104 344.0 COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,2TRNV@28211|Alphaproteobacteria,3JTDK@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C it plays a direct role in the translocation of protons across the membrane atpB - - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - - ATP-synt_A CMS1_k127_249313_16 323098.Nwi_0237 6.109e-36 137.0 COG0636@1|root,COG0636@2|Bacteria,1MZBU@1224|Proteobacteria,2UFPN@28211|Alphaproteobacteria,3K02Q@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpE - - ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_C CMS1_k127_249313_12 639283.Snov_4432 6.148e-45 169.0 COG0711@1|root,COG0711@2|Bacteria,1MZGU@1224|Proteobacteria,2UBVW@28211|Alphaproteobacteria,3EZF9@335928|Xanthobacteraceae 28211|Alphaproteobacteria C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpF2 - - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_B CMS1_k127_249313_11 113395.AXAI01000007_gene1495 4.187e-46 177.0 COG0711@1|root,COG0711@2|Bacteria,1N0P5@1224|Proteobacteria,2U5DD@28211|Alphaproteobacteria,3JY46@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpF - - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_B CMS1_k127_249313_10 316057.RPD_0243 7.093e-47 176.0 COG0637@1|root,COG0637@2|Bacteria,1NSPA@1224|Proteobacteria,2U0W3@28211|Alphaproteobacteria,3JT7R@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S HAD-hyrolase-like MA20_23860 - - - - - - - - - - - HAD_2 CMS1_k127_249313_13 1187851.A33M_1975 1.019e-38 154.0 2CB63@1|root,3349C@2|Bacteria,1RKRV@1224|Proteobacteria,2U0FI@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_249313_6 1187851.A33M_1976 6.742e-91 302.0 COG1670@1|root,COG1670@2|Bacteria,1MVG4@1224|Proteobacteria,2TUIK@28211|Alphaproteobacteria,3FD4Z@34008|Rhodovulum 28211|Alphaproteobacteria J Acetyltransferase (GNAT) domain rimJ - 2.3.1.128 ko:K03790 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 CMS1_k127_249313_2 316056.RPC_4796 3.426e-173 567.0 COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2TR39@28211|Alphaproteobacteria,3JR41@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Belongs to the peptidase M16 family mpp - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C CMS1_k127_249313_1 1187851.A33M_1978 9.543e-204 643.0 COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,2TT0D@28211|Alphaproteobacteria,3FDJV@34008|Rhodovulum 28211|Alphaproteobacteria E Threonine synthase N terminus thrC GO:0003674,GO:0003824,GO:0004795,GO:0006082,GO:0006520,GO:0006566,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016053,GO:0016311,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 - - - PALP,Thr_synth_N CMS1_k127_249313_3 189753.AXAS01000058_gene147 5.156e-110 360.0 COG1028@1|root,COG1028@2|Bacteria,1RBGC@1224|Proteobacteria,2U6FD@28211|Alphaproteobacteria,3JXHW@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria IQ Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short_C2 CMS1_k127_249313_15 1411123.JQNH01000001_gene405 2.586e-36 141.0 COG3346@1|root,COG3346@2|Bacteria,1MWWG@1224|Proteobacteria,2U0N5@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Surf1-like protein surf1 - - ko:K14998 - - - - ko00000,ko03029 3.D.4.8 - - SURF1 CMS1_k127_250000_0 331869.BAL199_02804 3.622e-212 680.0 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria 28211|Alphaproteobacteria T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,PAS_3,PAS_4,Response_reg CMS1_k127_250000_1 172088.AUGA01000044_gene6941 1.489e-132 432.0 COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,2TQSP@28211|Alphaproteobacteria,3JR4I@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage uvrB - - ko:K03702 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - Helicase_C,ResIII,UVR,UvrB CMS1_k127_2506567_3 1131814.JAFO01000001_gene2475 1.428e-58 209.0 COG0115@1|root,COG0115@2|Bacteria,1MVAT@1224|Proteobacteria,2TR7R@28211|Alphaproteobacteria,3EYM4@335928|Xanthobacteraceae 28211|Alphaproteobacteria EH Amino-transferase class IV dat GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016769,GO:0019478,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046416,GO:0046437,GO:0047810,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.6.1.21 ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 - R01148,R01582,R02459,R02851,R02924,R05053 RC00006,RC00008,RC00025 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_4 CMS1_k127_2506567_1 1187851.A33M_2255 2.39e-240 750.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQW2@28211|Alphaproteobacteria,3FCSX@34008|Rhodovulum 28211|Alphaproteobacteria T Sigma-54 interaction domain ntrX - - ko:K13599 ko02020,map02020 M00498 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat CMS1_k127_2506567_0 1187851.A33M_2254 2.294e-303 947.0 COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,2TQTB@28211|Alphaproteobacteria,3FCRE@34008|Rhodovulum 28211|Alphaproteobacteria T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain ntrY GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 ko:K13598 ko02020,map02020 M00498 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,PAS_4 CMS1_k127_2506567_2 1187851.A33M_2253 5.096e-172 542.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria,3FCIS@34008|Rhodovulum 28211|Alphaproteobacteria T Sigma-54 interaction domain ntrC - - ko:K07712 ko02020,map02020 M00497 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activ_2,Sigma54_activat CMS1_k127_2513872_13 1255043.TVNIR_1743 5.132e-10 65.0 COG5033@1|root,COG5033@2|Bacteria,1NBJM@1224|Proteobacteria,1SGE8@1236|Gammaproteobacteria 1236|Gammaproteobacteria K YEATS family - - - - - - - - - - - - YEATS CMS1_k127_2513872_12 468059.AUHA01000002_gene622 4.215e-12 73.0 2F8TK@1|root,3415N@2|Bacteria,4P43P@976|Bacteroidetes,1IYQK@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - CMS1_k127_2513872_6 395964.KE386496_gene183 8.887e-35 140.0 COG0758@1|root,COG0758@2|Bacteria,1MZGB@1224|Proteobacteria,2UG1X@28211|Alphaproteobacteria 28211|Alphaproteobacteria LU Putative molybdenum carrier - - - - - - - - - - - - MoCo_carrier CMS1_k127_2513872_8 1071679.BG57_17755 1.127e-25 115.0 COG0412@1|root,COG0412@2|Bacteria,1MW88@1224|Proteobacteria,2VQD1@28216|Betaproteobacteria,1JZSD@119060|Burkholderiaceae 28216|Betaproteobacteria Q Carboxymethylenebutenolidase clcD - 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 - R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 - - - DLH CMS1_k127_2513872_10 744980.TRICHSKD4_1996 1.063e-20 93.0 COG2885@1|root,COG2885@2|Bacteria,1MYXS@1224|Proteobacteria,2UBGB@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Belongs to the ompA family - - - - - - - - - - - - OmpA CMS1_k127_2513872_4 331869.BAL199_06988 1.158e-67 236.0 COG3791@1|root,COG3791@2|Bacteria,1RCYS@1224|Proteobacteria,2U5UG@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Glutathione-dependent formaldehyde-activating enzyme MA20_19505 - - - - - - - - - - - GFA CMS1_k127_2513872_3 1038866.KB902771_gene3695 3.19e-69 243.0 COG0526@1|root,COG0526@2|Bacteria,1QTY9@1224|Proteobacteria,2TW6Y@28211|Alphaproteobacteria,3JRHB@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria CO Thioredoxin-like - - - - - - - - - - - - AhpC-TSA,NHL,Redoxin,Thioredoxin_8 CMS1_k127_2513872_0 1187851.A33M_0224 2.727e-116 380.0 COG1226@1|root,2Z9WE@2|Bacteria,1QV7C@1224|Proteobacteria,2TU7Y@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Ion transport 2 domain protein - - - ko:K10716 - - - - ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 - - Ion_trans,Ion_trans_2 CMS1_k127_2513872_11 316058.RPB_1157 1.425e-18 88.0 2EHHA@1|root,33B97@2|Bacteria,1NINN@1224|Proteobacteria,2UK9H@28211|Alphaproteobacteria,3K5IG@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_2513872_14 1040989.AWZU01000035_gene1751 3.096e-09 59.0 2DK2Y@1|root,3089X@2|Bacteria,1NPJ5@1224|Proteobacteria,2UKXX@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_2513872_1 622637.KE124774_gene301 2.482e-87 300.0 COG3000@1|root,COG3000@2|Bacteria,1MW5G@1224|Proteobacteria,2TU63@28211|Alphaproteobacteria,370UH@31993|Methylocystaceae 28211|Alphaproteobacteria I Fatty acid hydroxylase superfamily - - - - - - - - - - - - FA_hydroxylase CMS1_k127_2513872_5 1333998.M2A_2139 6.076e-56 214.0 COG2249@1|root,COG2249@2|Bacteria,1RA5X@1224|Proteobacteria,2U7JU@28211|Alphaproteobacteria,4BTCF@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria S Flavodoxin-like fold - - - - - - - - - - - - Flavodoxin_2 CMS1_k127_2513872_9 414684.RC1_1853 2.411e-22 110.0 COG5589@1|root,COG5589@2|Bacteria,1N6W5@1224|Proteobacteria,2UFIE@28211|Alphaproteobacteria,2JTVV@204441|Rhodospirillales 204441|Rhodospirillales S Protein of unknown function (DUF2390) - - - - - - - - - - - - DUF2390 CMS1_k127_2513872_2 1028800.RG540_PA12590 1.515e-83 287.0 COG0715@1|root,COG0715@2|Bacteria 2|Bacteria P thiamine-containing compound biosynthetic process - - - ko:K02051,ko:K15553 ko00920,ko02010,map00920,map02010 M00188,M00436 - - ko00000,ko00001,ko00002,ko02000 3.A.1.16,3.A.1.17,3.A.1.17.2 - - NMT1,NMT1_2 CMS1_k127_2513872_7 998674.ATTE01000001_gene3828 5.462e-30 127.0 COG2358@1|root,COG2358@2|Bacteria,1R8QD@1224|Proteobacteria,1S5V9@1236|Gammaproteobacteria 1236|Gammaproteobacteria S TIGRFAM TRAP transporter solute receptor, TAXI family - - - ko:K07080 - - - - ko00000 - - - NMT1_3 CMS1_k127_2517533_0 1187851.A33M_3833 2.485e-170 541.0 COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,2TQTG@28211|Alphaproteobacteria,3FDN3@34008|Rhodovulum 28211|Alphaproteobacteria E B12 binding domain metH GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans CMS1_k127_2517533_1 1187851.A33M_3831 1.743e-144 463.0 COG0685@1|root,COG0685@2|Bacteria,1MUC9@1224|Proteobacteria,2TQZA@28211|Alphaproteobacteria,3FCXI@34008|Rhodovulum 28211|Alphaproteobacteria E Methylenetetrahydrofolate reductase metF GO:0003674,GO:0003824,GO:0004489,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.20 ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 M00377 R01224,R07168 RC00081 ko00000,ko00001,ko00002,ko01000 - - - MTHFR CMS1_k127_2517533_2 1187851.A33M_3830 6.696e-143 461.0 COG0500@1|root,COG0640@1|root,COG0640@2|Bacteria,COG2226@2|Bacteria,1NFSV@1224|Proteobacteria,2TSMV@28211|Alphaproteobacteria 28211|Alphaproteobacteria KQ arsR family arsR - - - - - - - - - - - HTH_20,HTH_5,Methyltransf_11,Methyltransf_31 CMS1_k127_253875_0 1297865.APJD01000002_gene4045 5.21e-317 981.0 COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,2TS8I@28211|Alphaproteobacteria,3JRH5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Pyridine nucleotide-disulphide oxidoreductase nirB - 1.2.1.58,1.7.1.15 ko:K00362,ko:K18359 ko00360,ko00910,ko01120,map00360,map00910,map01120 M00530 R00787,R02450 RC00004,RC00176,RC02860 br01601,ko00000,ko00001,ko00002,ko01000 - - - Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2,Rieske_2 CMS1_k127_2551005_1 1279015.KB908462_gene1900 1.064e-95 344.0 COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,1RMH7@1236|Gammaproteobacteria 1236|Gammaproteobacteria S TRAP transporter, 4TM 12TM fusion protein - - - - - - - - - - - - DctM CMS1_k127_2551005_2 1238182.C882_3365 2.629e-28 128.0 COG2358@1|root,COG2358@2|Bacteria,1MXW1@1224|Proteobacteria,2TSK2@28211|Alphaproteobacteria,2JPCR@204441|Rhodospirillales 204441|Rhodospirillales S NMT1-like family - - - ko:K07080 - - - - ko00000 - - - NMT1_3 CMS1_k127_2551005_0 864069.MicloDRAFT_00008450 2.579e-155 511.0 COG0477@1|root,COG2814@2|Bacteria,1MX2Q@1224|Proteobacteria,2TRNS@28211|Alphaproteobacteria,1JU1T@119045|Methylobacteriaceae 28211|Alphaproteobacteria EGP Major facilitator superfamily MA20_15570 - - - - - - - - - - - MFS_1 CMS1_k127_2551005_3 136993.KB900626_gene1647 6.209e-16 81.0 COG2173@1|root,COG2173@2|Bacteria,1RENK@1224|Proteobacteria,2TRK8@28211|Alphaproteobacteria,36YEG@31993|Methylocystaceae 28211|Alphaproteobacteria M D-ala-D-ala dipeptidase ddpX - 3.4.13.22 ko:K08641 ko01502,ko02020,map01502,map02020 M00651 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 - - - Peptidase_M15 CMS1_k127_2577072_1 1380394.JADL01000010_gene4329 8.611e-84 284.0 COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1MWRF@1224|Proteobacteria,2TS2A@28211|Alphaproteobacteria,2JVIJ@204441|Rhodospirillales 204441|Rhodospirillales S CHAT domain - - - - - - - - - - - - CHAT CMS1_k127_2577072_2 1380394.JADL01000001_gene2526 4.964e-25 113.0 2F5Y8@1|root,33YGV@2|Bacteria,1MV4P@1224|Proteobacteria,2TUJF@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - MA20_10390 - - - - - - - - - - - - CMS1_k127_2577072_0 335659.S23_56900 1.396e-103 366.0 COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,2TU52@28211|Alphaproteobacteria,3JSN7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T CHASE2 - - 4.6.1.1,4.6.1.2 ko:K01768,ko:K01769 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - CHASE2,Guanylate_cyc CMS1_k127_2577072_3 420324.KI911970_gene1558 4.76e-10 63.0 COG0642@1|root,COG2202@1|root,COG4585@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG4585@2|Bacteria,1MWPN@1224|Proteobacteria,2TSY5@28211|Alphaproteobacteria,1JZGS@119045|Methylobacteriaceae 28211|Alphaproteobacteria T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - HAMP,HATPase_c,HisKA_3,PAS_4 CMS1_k127_2577072_4 1219045.BV98_003305 5.664e-05 47.0 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,2K01C@204457|Sphingomonadales 204457|Sphingomonadales T Histidine kinase - - - - - - - - - - - - GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,Response_reg CMS1_k127_259469_10 266779.Meso_1125 7.529e-42 159.0 COG1196@1|root,COG1196@2|Bacteria,1QY4Z@1224|Proteobacteria,2TXFY@28211|Alphaproteobacteria,43RRX@69277|Phyllobacteriaceae 28211|Alphaproteobacteria D nuclear chromosome segregation - - - - - - - - - - - - - CMS1_k127_259469_4 1040989.AWZU01000004_gene7104 3.192e-156 506.0 COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,2U21P@28211|Alphaproteobacteria,3JWJB@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M tail specific protease - - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - PDZ_2,Peptidase_S41 CMS1_k127_259469_14 1380394.JADL01000012_gene868 1.193e-16 83.0 28YT2@1|root,2ZKKC@2|Bacteria,1N93U@1224|Proteobacteria,2UF4E@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_259469_6 1038859.AXAU01000012_gene4276 1.617e-90 305.0 COG0730@1|root,COG0730@2|Bacteria,1RCVI@1224|Proteobacteria,2U5XM@28211|Alphaproteobacteria,3JQXX@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Sulfite exporter TauE/SafE MA20_18170 - - ko:K07090 - - - - ko00000 - - - TauE CMS1_k127_259469_5 450851.PHZ_c0451 1.219e-95 323.0 COG1105@1|root,COG1105@2|Bacteria,1MVNW@1224|Proteobacteria,2U1H0@28211|Alphaproteobacteria 28211|Alphaproteobacteria H belongs to the carbohydrate kinase PfkB family - - 2.7.1.11 ko:K16370 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00345 R00756,R03236,R03237,R03238,R03239,R04779 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - PfkB CMS1_k127_259469_11 1267005.KB911255_gene3030 9.441e-42 162.0 COG0860@1|root,COG0860@2|Bacteria 2|Bacteria M N-Acetylmuramoyl-L-alanine amidase - GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008745,GO:0016787,GO:0016810,GO:0016811,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0061783 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3 CMS1_k127_259469_2 1038859.AXAU01000010_gene1746 4.382e-174 558.0 COG1368@1|root,COG1368@2|Bacteria,1R6IX@1224|Proteobacteria,2UQZM@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Sulfatase - - - - - - - - - - - - Sulfatase CMS1_k127_259469_1 318996.AXAZ01000045_gene1456 8.297e-186 588.0 COG0717@1|root,COG0717@2|Bacteria,1MVDH@1224|Proteobacteria,2TR5U@28211|Alphaproteobacteria,3JRYW@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria F 2'-deoxycytidine 5'-triphosphate deaminase (DCD) dcd - 3.5.4.13 ko:K01494 ko00240,ko01100,map00240,map01100 M00053 R00568,R02325 RC00074 ko00000,ko00001,ko00002,ko01000 - - - DCD CMS1_k127_259469_0 709797.CSIRO_1266 2.784e-188 594.0 COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,2TTMF@28211|Alphaproteobacteria,3JR3R@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide metZ GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48 ko:K01739,ko:K10764 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017 R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00420,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 - - - Cys_Met_Meta_PP CMS1_k127_259469_7 1187851.A33M_4160 1.077e-66 237.0 COG2755@1|root,COG2755@2|Bacteria,1MWPZ@1224|Proteobacteria,2TSYR@28211|Alphaproteobacteria 28211|Alphaproteobacteria E PFAM lipolytic protein G-D-S-L family - - - - - - - - - - - - Lipase_GDSL_2 CMS1_k127_259469_8 1187851.A33M_4161 5.478e-60 216.0 COG2755@1|root,COG2755@2|Bacteria,1R505@1224|Proteobacteria,2TT25@28211|Alphaproteobacteria 28211|Alphaproteobacteria E lipolytic protein G-D-S-L family - - - - - - - - - - - - Lipase_GDSL_2 CMS1_k127_259469_3 1187851.A33M_4162 9.503e-157 504.0 COG4645@1|root,COG4645@2|Bacteria,1PI9Q@1224|Proteobacteria,2U1C7@28211|Alphaproteobacteria,3FEFQ@34008|Rhodovulum 28211|Alphaproteobacteria S OpgC protein MA20_22360 - - - - - - - - - - - OpgC_C CMS1_k127_259469_9 1297863.APJF01000022_gene4475 1.124e-53 191.0 COG2967@1|root,COG2967@2|Bacteria,1MZ2Z@1224|Proteobacteria,2U9JM@28211|Alphaproteobacteria,3JY59@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P ApaG domain apaG - - ko:K06195 - - - - ko00000 - - - DUF525 CMS1_k127_259469_13 573370.DMR_14120 2.145e-29 126.0 COG3786@1|root,COG3786@2|Bacteria,1RH22@1224|Proteobacteria,42U32@68525|delta/epsilon subdivisions,2WSHT@28221|Deltaproteobacteria,2M9M3@213115|Desulfovibrionales 28221|Deltaproteobacteria S Protein conserved in bacteria - - - - - - - - - - - - YkuD CMS1_k127_259469_12 1297865.APJD01000003_gene6376 4.314e-34 132.0 COG1281@1|root,COG1281@2|Bacteria,1MUMU@1224|Proteobacteria,2TTUR@28211|Alphaproteobacteria,3JTPI@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress hslO - - ko:K04083 - - - - ko00000,ko03110 - - - HSP33 CMS1_k127_2607134_6 1211115.ALIQ01000002_gene4365 3.674e-12 69.0 COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,2TUF7@28211|Alphaproteobacteria,3N9SD@45404|Beijerinckiaceae 28211|Alphaproteobacteria I CDP-alcohol phosphatidyltransferase pssA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.8.8 ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 M00093 R01800 RC00002,RC00017,RC02795 ko00000,ko00001,ko00002,ko01000 - - - CDP-OH_P_tran_2,CDP-OH_P_transf CMS1_k127_2607134_2 113395.AXAI01000006_gene1615 6.831e-112 366.0 COG0688@1|root,COG0688@2|Bacteria,1MW45@1224|Proteobacteria,2TRMG@28211|Alphaproteobacteria,3JRU2@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) psd - 4.1.1.65 ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 M00093 R02055 RC00299 ko00000,ko00001,ko00002,ko01000 - - - PS_Dcarbxylase CMS1_k127_2607134_0 113395.AXAI01000006_gene1614 5.57e-313 970.0 COG5265@1|root,COG5265@2|Bacteria,1NSKS@1224|Proteobacteria,2UQAG@28211|Alphaproteobacteria,3JSVP@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria V ABC transporter atm1 GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006996,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009507,GO:0009526,GO:0009536,GO:0009555,GO:0009657,GO:0009658,GO:0009889,GO:0009941,GO:0009987,GO:0010035,GO:0010038,GO:0010288,GO:0010380,GO:0016020,GO:0016043,GO:0018130,GO:0019222,GO:0019538,GO:0019637,GO:0019720,GO:0019725,GO:0019866,GO:0022622,GO:0030003,GO:0031090,GO:0031323,GO:0031326,GO:0031966,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0042221,GO:0042592,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044429,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0046686,GO:0046916,GO:0048229,GO:0048364,GO:0048731,GO:0048856,GO:0048878,GO:0050789,GO:0050790,GO:0050794,GO:0050801,GO:0050896,GO:0051171,GO:0051186,GO:0051188,GO:0051189,GO:0051193,GO:0051276,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0065009,GO:0071704,GO:0071840,GO:0090056,GO:0090407,GO:0098771,GO:0099402,GO:1901360,GO:1901362,GO:1901401,GO:1901463,GO:1901564,GO:1901566,GO:1901576 - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran CMS1_k127_2607134_4 1197906.CAJQ02000016_gene130 1.901e-70 267.0 COG1611@1|root,COG1611@2|Bacteria,1RD59@1224|Proteobacteria,2U5DP@28211|Alphaproteobacteria,3JU4A@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Belongs to the LOG family yvdD - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox CMS1_k127_2607134_1 1231391.AMZF01000022_gene1229 8.623e-215 681.0 COG0654@1|root,COG0654@2|Bacteria,1MUN4@1224|Proteobacteria,2VN4I@28216|Betaproteobacteria,3T6WQ@506|Alcaligenaceae 28216|Betaproteobacteria CH FAD binding domain - - - - - - - - - - - - FAD_binding_3 CMS1_k127_2607134_5 113395.AXAI01000006_gene1612 3.396e-46 171.0 COG0346@1|root,COG0346@2|Bacteria,1RH4D@1224|Proteobacteria,2U7GX@28211|Alphaproteobacteria,3JYQ4@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase CMS1_k127_2607134_3 224911.27352053 2.639e-82 275.0 COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,2TSK4@28211|Alphaproteobacteria,3JUJJ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Belongs to the alpha-IPM synthase homocitrate synthase family MA20_26350 - 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 - - - HMGL-like,LeuA_dimer CMS1_k127_262114_1 1187851.A33M_1129 1.135e-131 428.0 COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2TQN9@28211|Alphaproteobacteria,3FCTN@34008|Rhodovulum 28211|Alphaproteobacteria E Pyridoxal-phosphate dependent enzyme tdcB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006520,GO:0006563,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016841,GO:0016853,GO:0016854,GO:0016855,GO:0017144,GO:0018249,GO:0019538,GO:0019752,GO:0019842,GO:0030170,GO:0030378,GO:0030848,GO:0036094,GO:0036211,GO:0036361,GO:0042219,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046416,GO:0046437,GO:0046872,GO:0047661,GO:0048037,GO:0050662,GO:0070178,GO:0070179,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901607 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP CMS1_k127_262114_4 1279019.ARQK01000058_gene761 5.219e-102 338.0 COG0500@1|root,COG2226@2|Bacteria,1MXP4@1224|Proteobacteria,1S7AD@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q ubiE/COQ5 methyltransferase family - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 CMS1_k127_262114_5 439496.RBY4I_3230 1.712e-79 275.0 COG1733@1|root,COG1733@2|Bacteria,1NEKW@1224|Proteobacteria,2U0MC@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Transcriptional regulator - - - - - - - - - - - - HxlR,SCP2 CMS1_k127_262114_3 1187851.A33M_0951 1.436e-109 360.0 COG1028@1|root,COG1028@2|Bacteria,1MWJI@1224|Proteobacteria,2TRNJ@28211|Alphaproteobacteria,3FCZZ@34008|Rhodovulum 28211|Alphaproteobacteria IQ Enoyl-(Acyl carrier protein) reductase - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 CMS1_k127_262114_8 666684.AfiDRAFT_0861 2.517e-22 99.0 COG2199@1|root,COG3706@2|Bacteria,1NAVK@1224|Proteobacteria,2UF4H@28211|Alphaproteobacteria,3K0YM@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T PilZ domain - - - - - - - - - - - - PilZ CMS1_k127_262114_7 420324.KI912051_gene6015 4.362e-42 163.0 COG2020@1|root,COG2020@2|Bacteria,1N4VF@1224|Proteobacteria,2UFPE@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - - - - - - - - - - ICMT,PEMT CMS1_k127_262114_2 595537.Varpa_0813 1.452e-117 384.0 COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,2VI5Z@28216|Betaproteobacteria,4AA1T@80864|Comamonadaceae 28216|Betaproteobacteria Q PFAM fumarylacetoacetate (FAA) hydrolase - - - - - - - - - - - - FAA_hydrolase CMS1_k127_262114_0 1187851.A33M_0396 7.371e-184 587.0 COG5323@1|root,COG5323@2|Bacteria,1MW8S@1224|Proteobacteria,2TREI@28211|Alphaproteobacteria,3FCK4@34008|Rhodovulum 28211|Alphaproteobacteria S Terminase RNaseH-like domain - - - - - - - - - - - - Terminase_6,Terminase_6C CMS1_k127_262114_10 652103.Rpdx1_3619 9.407e-08 63.0 2DS6E@1|root,33ES8@2|Bacteria,1NJQC@1224|Proteobacteria,2UJKY@28211|Alphaproteobacteria,3K5C2@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - Terminase_5 CMS1_k127_262114_9 113395.AXAI01000014_gene320 1.807e-19 100.0 COG0664@1|root,COG0664@2|Bacteria,1QW7C@1224|Proteobacteria,2TWR0@28211|Alphaproteobacteria,3K6MN@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - - - - - - - - - - cNMP_binding CMS1_k127_262114_6 1380394.JADL01000001_gene2665 6.101e-48 185.0 COG3247@1|root,COG3247@2|Bacteria,1R63F@1224|Proteobacteria,2U3AR@28211|Alphaproteobacteria,2JUM2@204441|Rhodospirillales 204441|Rhodospirillales S Short repeat of unknown function (DUF308) - - - - - - - - - - - - DUF308 CMS1_k127_262114_11 1245469.S58_49720 6.95e-05 46.0 COG0587@1|root,COG0587@2|Bacteria,1MUE4@1224|Proteobacteria,2TRUB@28211|Alphaproteobacteria,3JUU5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase dnaE2 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 ko:K02337,ko:K14162 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon CMS1_k127_263551_2 1101190.ARWB01000001_gene1255 2.193e-67 231.0 COG0223@1|root,COG0223@2|Bacteria,1MW07@1224|Proteobacteria,2U0GD@28211|Alphaproteobacteria,371CA@31993|Methylocystaceae 28211|Alphaproteobacteria J Formyl transferase, C-terminal domain - - 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 - R03940 RC00026,RC00165 ko00000,ko00001,ko01000 - - - Formyl_trans_C,Formyl_trans_N CMS1_k127_263551_1 1038859.AXAU01000010_gene1745 3.983e-230 730.0 COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TTM5@28211|Alphaproteobacteria,3JR50@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate frc - 2.8.3.16 ko:K07749 - - - - ko00000,ko01000 - - - CoA_transf_3 CMS1_k127_263551_0 1297863.APJF01000013_gene4051 0.0 1041.0 COG0028@1|root,COG0028@2|Bacteria,1MXDW@1224|Proteobacteria,2TT9X@28211|Alphaproteobacteria,3JRKI@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria EH Belongs to the TPP enzyme family oxc - 2.2.1.6,4.1.1.8 ko:K01577,ko:K01652 ko00290,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R01908,R03050,R04672,R04673,R08648 RC00027,RC00106,RC00620,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N CMS1_k127_26402_6 1211115.ALIQ01000060_gene3434 2.122e-30 120.0 COG3386@1|root,COG3386@2|Bacteria,1MU0C@1224|Proteobacteria,2TSXG@28211|Alphaproteobacteria,3NCCT@45404|Beijerinckiaceae 28211|Alphaproteobacteria G SMP-30/Gluconolaconase/LRE-like region - - 3.1.1.17 ko:K01053,ko:K14274 ko00030,ko00040,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00040,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220 M00129 R01519,R02427,R02933,R03751 RC00537,RC00713,RC00983 ko00000,ko00001,ko00002,ko01000,ko04147 - - - SGL CMS1_k127_26402_0 1411123.JQNH01000001_gene841 6.975e-183 582.0 COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TR7Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria C L-carnitine dehydratase bile acid-inducible protein F - - - - - - - - - - - - CoA_transf_3 CMS1_k127_26402_2 1411123.JQNH01000001_gene840 2.106e-100 333.0 COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,2U6QF@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Enoyl-CoA hydratase/isomerase - - - - - - - - - - - - ECH_1 CMS1_k127_26402_1 290400.Jann_2941 2.468e-125 415.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TRM1@28211|Alphaproteobacteria 28211|Alphaproteobacteria G COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - - - - - - - - - - DctM CMS1_k127_26402_7 290400.Jann_2942 5.065e-22 103.0 COG3090@1|root,COG3090@2|Bacteria,1QYHJ@1224|Proteobacteria,2UI8I@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Tripartite ATP-independent periplasmic transporters, DctQ component - - - - - - - - - - - - DctQ CMS1_k127_26402_4 290400.Jann_2943 1.573e-82 288.0 COG1638@1|root,COG1638@2|Bacteria,1MUJY@1224|Proteobacteria,2TQNU@28211|Alphaproteobacteria 28211|Alphaproteobacteria G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - - - - - - - - - - DctP CMS1_k127_26402_5 290400.Jann_2940 3.507e-74 260.0 COG0583@1|root,COG0583@2|Bacteria,1R550@1224|Proteobacteria,2U4SA@28211|Alphaproteobacteria 28211|Alphaproteobacteria K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate CMS1_k127_26402_8 331869.BAL199_30512 3.649e-16 86.0 COG1961@1|root,COG1961@2|Bacteria,1RAYT@1224|Proteobacteria,2UKS5@28211|Alphaproteobacteria 28211|Alphaproteobacteria L COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - - - - - - - - - - - CMS1_k127_26402_3 189753.AXAS01000041_gene2523 3.359e-88 298.0 COG0582@1|root,COG0582@2|Bacteria,1P1R9@1224|Proteobacteria,2U190@28211|Alphaproteobacteria,3JVWC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L Phage integrase family - - - - - - - - - - - - Phage_integrase CMS1_k127_2645722_3 1120934.KB894419_gene2119 6.072e-103 350.0 COG2936@1|root,COG2936@2|Bacteria,2GKZH@201174|Actinobacteria,4E0CY@85010|Pseudonocardiales 201174|Actinobacteria S X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain - - - ko:K06978 - - - - ko00000 - - - PepX_C,Peptidase_S15 CMS1_k127_2645722_0 1123239.KB898631_gene2323 9.384e-142 460.0 COG4948@1|root,COG4948@2|Bacteria,1U140@1239|Firmicutes,4HAT9@91061|Bacilli 91061|Bacilli M Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - - - - - - - - - - MR_MLE_C CMS1_k127_2645722_1 1231391.AMZF01000037_gene583 3.463e-131 427.0 COG1878@1|root,COG1878@2|Bacteria,1MVWU@1224|Proteobacteria,2VI5X@28216|Betaproteobacteria,3T6F3@506|Alcaligenaceae 28216|Betaproteobacteria S Putative cyclase - - - - - - - - - - - - Cyclase CMS1_k127_2645722_2 1394178.AWOO02000008_gene2961 7.433e-126 411.0 COG0028@1|root,COG0028@2|Bacteria,2I9V6@201174|Actinobacteria 201174|Actinobacteria EH Belongs to the TPP enzyme family - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N CMS1_k127_264856_0 348824.LPU83_4057 1.039e-90 306.0 COG3335@1|root,COG3335@2|Bacteria,1RB1C@1224|Proteobacteria,2U367@28211|Alphaproteobacteria,4BC4T@82115|Rhizobiaceae 28211|Alphaproteobacteria L protein y4pE y4sA - - - - - - - - - - - - DDE_3 CMS1_k127_264856_1 1238182.C882_1327 7.194e-61 216.0 COG3415@1|root,COG3415@2|Bacteria,1RDMQ@1224|Proteobacteria,2U7PU@28211|Alphaproteobacteria,2JZ7V@204441|Rhodospirillales 204441|Rhodospirillales L Winged helix-turn helix - - - - - - - - - - - - HTH_32,HTH_33 CMS1_k127_266038_0 1297863.APJF01000001_gene2091 8.718e-221 706.0 COG3164@1|root,COG3164@2|Bacteria,1MVDY@1224|Proteobacteria,2TSGG@28211|Alphaproteobacteria,3JTCH@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function MA20_30770 - - - - - - - - - - - AsmA_2,DUF3971 CMS1_k127_266038_2 319003.Bra1253DRAFT_01774 1.194e-27 115.0 COG4786@1|root,COG4786@2|Bacteria,1MZXB@1224|Proteobacteria,2TTM8@28211|Alphaproteobacteria,3JW7P@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria N Protein of unknown function (DUF2950) - - - - - - - - - - - - DUF2950 CMS1_k127_266038_1 1187851.A33M_3366 1.68e-161 513.0 COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,2TQPA@28211|Alphaproteobacteria,3FCKS@34008|Rhodovulum 28211|Alphaproteobacteria J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - S4,tRNA-synt_1b CMS1_k127_2697843_0 319003.Bra1253DRAFT_07051 8.469e-128 413.0 COG2368@1|root,COG2368@2|Bacteria,1PEQG@1224|Proteobacteria,2TVQ7@28211|Alphaproteobacteria,3JWEV@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria Q 4-hydroxyphenylacetate 3-hydroxylase C terminal - - 1.14.14.9 ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 - R02698,R03299 RC00046 ko00000,ko00001,ko01000 - - - HpaB,HpaB_N CMS1_k127_2697843_1 991905.SL003B_4177 6.707e-92 308.0 COG2223@1|root,COG2223@2|Bacteria,1QVKP@1224|Proteobacteria,2TRVV@28211|Alphaproteobacteria,4BR8Y@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria P Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 CMS1_k127_2698382_2 1429916.X566_11345 4.813e-112 363.0 COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,2TQK1@28211|Alphaproteobacteria,3JT7I@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Branched-chain amino acid ATP-binding cassette transporter cysA - - ko:K01995,ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C CMS1_k127_2698382_1 1211115.ALIQ01000225_gene1816 3.572e-166 526.0 COG0559@1|root,COG0559@2|Bacteria,1N54M@1224|Proteobacteria,2TTF5@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Belongs to the binding-protein-dependent transport system permease family livH3 - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 CMS1_k127_2698382_0 1211115.ALIQ01000225_gene1817 1.212e-170 541.0 COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,2TT26@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Belongs to the binding-protein-dependent transport system permease family livM - - ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 CMS1_k127_2698382_3 670292.JH26_06110 2.946e-98 327.0 COG0683@1|root,COG0683@2|Bacteria,1MV5T@1224|Proteobacteria,2TQZC@28211|Alphaproteobacteria,1JRPF@119045|Methylobacteriaceae 28211|Alphaproteobacteria E Periplasmic binding protein - - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 CMS1_k127_2704303_2 1121106.JQKB01000016_gene5290 1.028e-08 58.0 COG2175@1|root,COG2175@2|Bacteria,1Q0C7@1224|Proteobacteria,2TRGF@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q Taurine catabolism dioxygenase TauD, TfdA - - - - - - - - - - - - TauD CMS1_k127_2704303_0 1082931.KKY_2537 9.756e-87 297.0 COG0673@1|root,COG0673@2|Bacteria,1R4SZ@1224|Proteobacteria,2TRR2@28211|Alphaproteobacteria,3N8YQ@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria S Oxidoreductase family, C-terminal alpha/beta domain bplA - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C CMS1_k127_2704303_1 666684.AfiDRAFT_3131 1.404e-41 154.0 COG0028@1|root,COG0028@2|Bacteria,1R743@1224|Proteobacteria,2U4KA@28211|Alphaproteobacteria 28211|Alphaproteobacteria EH Thiamine pyrophosphate enzyme, central domain - - 3.7.1.22 ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 - R08603 RC02331 ko00000,ko00001,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N CMS1_k127_2705382_3 1211115.ALIQ01000225_gene1759 2.144e-47 175.0 COG3153@1|root,COG3153@2|Bacteria,1RD0C@1224|Proteobacteria,2U7AS@28211|Alphaproteobacteria,3NBBY@45404|Beijerinckiaceae 28211|Alphaproteobacteria S Acetyltransferase (GNAT) family MA20_06530 - - - - - - - - - - - Acetyltransf_1,Acetyltransf_9 CMS1_k127_2705382_1 1429916.X566_12980 5.322e-206 644.0 COG0019@1|root,COG0019@2|Bacteria,1MZ7Y@1224|Proteobacteria,2TSKB@28211|Alphaproteobacteria,3JRBN@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Belongs to the Orn Lys Arg decarboxylase class-II family speF - 4.1.1.17 ko:K01581 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 M00134 R00670 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC CMS1_k127_2705382_4 1187851.A33M_4145 1.7e-20 98.0 2EMGS@1|root,33F5F@2|Bacteria,1N1UH@1224|Proteobacteria,2UC3W@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - MA20_06520 - - - - - - - - - - - - CMS1_k127_2705382_0 335659.S23_66210 1.35e-249 784.0 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2TR56@28211|Alphaproteobacteria,3JW4E@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P Function proposed based on presence of conserved amino acid motif, structural feature or limited homology cadA - - - - - - - - - - - E1-E2_ATPase,Hemerythrin,HlyD_D23,Hydrolase CMS1_k127_2705382_2 1336243.JAEA01000001_gene1986 5.568e-204 647.0 COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,2TRCK@28211|Alphaproteobacteria,1JRCG@119045|Methylobacteriaceae 28211|Alphaproteobacteria E PFAM peptidase M3A and M3B thimet oligopeptidase F dcp GO:0003674,GO:0003824,GO:0004180,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0016787,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.15.5 ko:K01284 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3 CMS1_k127_2708613_6 936455.KI421499_gene2933 1.885e-148 474.0 COG0715@1|root,COG0715@2|Bacteria,1R8AT@1224|Proteobacteria,2U2Z7@28211|Alphaproteobacteria,3K3AI@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - - - - - - - - - - - CMS1_k127_2708613_18 1123023.JIAI01000003_gene2856 2.066e-43 169.0 COG2186@1|root,COG2186@2|Bacteria 2|Bacteria K Transcriptional regulator - - - ko:K05799 - - - - ko00000,ko03000 - - - FCD,GntR CMS1_k127_2708613_17 1230476.C207_06360 8.568e-44 166.0 COG2755@1|root,COG2755@2|Bacteria,1RC1Q@1224|Proteobacteria,2U6XX@28211|Alphaproteobacteria,3JYMT@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E GDSL-like Lipase/Acylhydrolase family - - - - - - - - - - - - Lipase_GDSL_2 CMS1_k127_2708613_4 314265.R2601_06378 1.432e-167 535.0 COG2159@1|root,COG2159@2|Bacteria,1N0C7@1224|Proteobacteria,2TRXY@28211|Alphaproteobacteria 28211|Alphaproteobacteria P PFAM amidohydrolase - - - ko:K07045 - - - - ko00000 - - - Amidohydro_2 CMS1_k127_2708613_21 1123023.JIAI01000003_gene2864 2.318e-33 133.0 COG2146@1|root,COG2146@2|Bacteria,2IFRC@201174|Actinobacteria,4E71A@85010|Pseudonocardiales 201174|Actinobacteria P Rieske [2Fe-2S] domain - - - - - - - - - - - - Rieske CMS1_k127_2708613_14 1510531.JQJJ01000009_gene662 5.289e-72 250.0 COG0730@1|root,COG0730@2|Bacteria,1MWAN@1224|Proteobacteria,2TS4X@28211|Alphaproteobacteria,3JS3F@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S membrane transporter protein MA20_06400 - - ko:K07090 - - - - ko00000 - - - TauE CMS1_k127_2708613_8 1038860.AXAP01000001_gene6477 1.624e-141 453.0 COG1878@1|root,COG1878@2|Bacteria,1Q49R@1224|Proteobacteria,2UI8Z@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Putative cyclase - - - - - - - - - - - - Cyclase CMS1_k127_2708613_7 709797.CSIRO_0034 6.92e-142 455.0 COG0596@1|root,COG0596@2|Bacteria,1NJ2B@1224|Proteobacteria,2TR54@28211|Alphaproteobacteria,3JQWT@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1 CMS1_k127_2708613_9 709797.CSIRO_0040 6.121e-138 443.0 COG1028@1|root,COG1028@2|Bacteria,1NBB6@1224|Proteobacteria,2TVF5@28211|Alphaproteobacteria,3JXK5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria IQ Enoyl-(Acyl carrier protein) reductase - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short,adh_short_C2 CMS1_k127_2708613_22 665959.HMPREF1013_03864 3.517e-28 123.0 COG3665@1|root,COG3665@2|Bacteria,1V2S5@1239|Firmicutes,4HGCJ@91061|Bacilli,1ZF9X@1386|Bacillus 91061|Bacilli S Domain of unknown function (DUF1989) - - - ko:K09967 - - - - ko00000 - - - DUF1989 CMS1_k127_2708613_3 1187851.A33M_4136 4.639e-196 619.0 COG0683@1|root,COG0683@2|Bacteria,1MWNB@1224|Proteobacteria,2TTAH@28211|Alphaproteobacteria 28211|Alphaproteobacteria E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component MA20_26550 - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 CMS1_k127_2708613_2 1187851.A33M_4134 3.899e-256 805.0 COG0559@1|root,COG4177@1|root,COG0559@2|Bacteria,COG4177@2|Bacteria,1MY1E@1224|Proteobacteria,2TTC6@28211|Alphaproteobacteria,3FE9K@34008|Rhodovulum 28211|Alphaproteobacteria U Branched-chain amino acid transport system / permease component - - - ko:K01997,ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 CMS1_k127_2708613_11 257310.BB1774 1.096e-101 360.0 COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,2VI2N@28216|Betaproteobacteria,3T2JX@506|Alcaligenaceae 28216|Betaproteobacteria E ABC-type branched-chain amino acid transport systems ATPase component - - - ko:K01995 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C CMS1_k127_2708613_10 1123504.JQKD01000010_gene2576 2.329e-103 347.0 COG0410@1|root,COG0410@2|Bacteria,1MUR3@1224|Proteobacteria,2VI3W@28216|Betaproteobacteria,4AAJ0@80864|Comamonadaceae 28216|Betaproteobacteria E ABC transporter - - - ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran CMS1_k127_2708613_16 639283.Snov_0283 2.083e-46 173.0 COG1846@1|root,COG1846@2|Bacteria,1N0MG@1224|Proteobacteria,2UDDI@28211|Alphaproteobacteria,3EZVM@335928|Xanthobacteraceae 28211|Alphaproteobacteria K helix_turn_helix multiple antibiotic resistance protein - - - ko:K22296 - - - - ko00000,ko03000 - - - MarR,MarR_2 CMS1_k127_2708613_1 1123060.JONP01000025_gene3359 7.05e-298 934.0 COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2U2QW@28211|Alphaproteobacteria,2JV3N@204441|Rhodospirillales 204441|Rhodospirillales C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - - - - - - - - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 CMS1_k127_2708613_13 1038860.AXAP01000009_gene7944 3.015e-78 264.0 COG2080@1|root,COG2080@2|Bacteria,1RJC4@1224|Proteobacteria,2U85C@28211|Alphaproteobacteria,3K635@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C [2Fe-2S] binding domain - - - - - - - - - - - - Fer2,Fer2_2 CMS1_k127_2708613_0 1038860.AXAP01000009_gene7943 3.351e-306 958.0 COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TQMW@28211|Alphaproteobacteria,3JSZE@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - - - - - - - - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 CMS1_k127_2708613_12 1123060.JONP01000025_gene3361 4.121e-85 290.0 COG1319@1|root,COG1319@2|Bacteria,1MUDB@1224|Proteobacteria,2TTJF@28211|Alphaproteobacteria 28211|Alphaproteobacteria C carbon monoxide dehydrogenase - - 1.2.5.3 ko:K03519 - - R11168 RC02800 ko00000,ko01000 - - - CO_deh_flav_C,FAD_binding_5 CMS1_k127_2708613_19 1333998.M2A_2228 5.621e-38 153.0 COG2845@1|root,COG2845@2|Bacteria,1R4X7@1224|Proteobacteria,2U5AU@28211|Alphaproteobacteria,4BT3D@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF459) - - - ko:K09795 - - - - ko00000 - - - DUF459,Lipase_GDSL_2 CMS1_k127_2708613_15 648757.Rvan_3294 6.866e-62 220.0 COG2928@1|root,COG2928@2|Bacteria,1PZ1I@1224|Proteobacteria,2V734@28211|Alphaproteobacteria,3N8W5@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF502) - - - - - - - - - - - - DUF502 CMS1_k127_2708613_5 402881.Plav_1959 1.571e-157 511.0 COG1696@1|root,COG1696@2|Bacteria,1MUXN@1224|Proteobacteria,2TRD1@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Membrane bound O-acyl transferase, MBOAT family protein algI - - - - - - - - - - - MBOAT CMS1_k127_2708613_20 472175.EL18_00139 3.142e-35 145.0 COG2845@1|root,COG2845@2|Bacteria,1R4X7@1224|Proteobacteria,2U5AU@28211|Alphaproteobacteria,43HMH@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF459) - - - ko:K09795 - - - - ko00000 - - - DUF459 CMS1_k127_2708637_3 1040989.AWZU01000042_gene67 1.21e-52 192.0 COG2981@1|root,COG2981@2|Bacteria,1MWAA@1224|Proteobacteria,2TT6E@28211|Alphaproteobacteria,3JT5R@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Etoposide-induced protein 2.4 (EI24) MA20_24505 - - ko:K06203 - - - - ko00000 - - - EI24 CMS1_k127_2708637_1 1038862.KB893845_gene6016 1.624e-112 377.0 28JXP@1|root,2Z9N4@2|Bacteria,1MXG4@1224|Proteobacteria,2TSXI@28211|Alphaproteobacteria,3JSBT@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family MA20_24470 - - - - - - - - - - - Peptidase_C92 CMS1_k127_2708637_0 316056.RPC_0443 3.108e-137 451.0 COG1231@1|root,COG1231@2|Bacteria,1MXYC@1224|Proteobacteria,2TVDF@28211|Alphaproteobacteria,3JUJ6@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Flavin containing amine oxidoreductase - - - - - - - - - - - - Amino_oxidase CMS1_k127_2708637_2 1038859.AXAU01000008_gene1896 5.608e-93 315.0 COG2102@1|root,COG2102@2|Bacteria,1R97Y@1224|Proteobacteria,2VG9S@28211|Alphaproteobacteria,3K6IP@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Diphthamide synthase - - - - - - - - - - - - Diphthami_syn_2 CMS1_k127_2708637_4 1038859.AXAU01000004_gene4762 1.549e-32 126.0 COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1MWKS@1224|Proteobacteria,2TQV8@28211|Alphaproteobacteria,3JUGP@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily pheT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - B3_4,B5,FDX-ACB,tRNA_bind CMS1_k127_2709889_1 1038859.AXAU01000003_gene6087 8.404e-86 296.0 COG1295@1|root,COG1295@2|Bacteria,1MXQA@1224|Proteobacteria,2TSFP@28211|Alphaproteobacteria,3K2VT@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Virulence factor BrkB - - - ko:K07058 - - - - ko00000 - - - Virul_fac_BrkB CMS1_k127_2709889_0 1211115.ALIQ01000018_gene2180 0.0 1150.0 COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,2TQZU@28211|Alphaproteobacteria,3NA05@45404|Beijerinckiaceae 28211|Alphaproteobacteria EF Carbamoyl-phosphate synthetase large chain, oligomerisation domain carB - 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS CMS1_k127_2710819_3 709797.CSIRO_0382 2.698e-108 372.0 COG3108@1|root,COG3108@2|Bacteria,1MWW2@1224|Proteobacteria,2TQZ1@28211|Alphaproteobacteria,3JUBS@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Bacterial protein of unknown function (DUF882) - - - - - - - - - - - - Peptidase_M15_2 CMS1_k127_2710819_8 323097.Nham_1221 4.113e-34 132.0 COG3750@1|root,COG3750@2|Bacteria,1N77J@1224|Proteobacteria,2UFX6@28211|Alphaproteobacteria,3JZE3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Belongs to the UPF0335 family MA20_03860 - - - - - - - - - - - DUF2312 CMS1_k127_2710819_7 384765.SIAM614_23942 2.295e-45 168.0 COG3492@1|root,COG3492@2|Bacteria,1MZ3I@1224|Proteobacteria,2UC11@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein conserved in bacteria MA20_03865 - - ko:K09948 - - - - ko00000 - - - DUF1244 CMS1_k127_2710819_0 935557.ATYB01000014_gene2950 2.123e-181 592.0 COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2TQVK@28211|Alphaproteobacteria,4B9W8@82115|Rhizobiaceae 28211|Alphaproteobacteria C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - 1.3.99.16 ko:K07303 - - - - ko00000,ko01000 - - - Ald_Xan_dh_C2 CMS1_k127_2710819_4 935557.ATYB01000014_gene2949 1.313e-73 251.0 COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,2U6Z6@28211|Alphaproteobacteria,4BEIQ@82115|Rhizobiaceae 28211|Alphaproteobacteria C [2Fe-2S] binding domain - - 1.3.99.16 ko:K00256,ko:K07302 - - - - ko00000,ko01000 - - - Fer2,Fer2_2 CMS1_k127_2710819_6 1304877.KI519399_gene5335 1.616e-61 215.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TRI3@28211|Alphaproteobacteria,3JUNS@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Aldehyde dehydrogenase family MA20_29510 - 1.2.1.67 ko:K21802 ko00627,ko01120,map00627,map01120 - R05699 RC00075 ko00000,ko00001,ko01000 - - - Aldedh CMS1_k127_2710819_1 1187851.A33M_3403 7.519e-168 541.0 COG2379@1|root,COG2379@2|Bacteria,1MVIK@1224|Proteobacteria,2TQJY@28211|Alphaproteobacteria,3FCHB@34008|Rhodovulum 28211|Alphaproteobacteria G MOFRL family MA20_18630 - 2.7.1.165 ko:K11529 ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200 M00346 R08572 RC00002,RC00428 ko00000,ko00001,ko00002,ko01000 - - - DUF4147,MOFRL CMS1_k127_2710819_5 936455.KI421499_gene5509 5.266e-67 233.0 COG5480@1|root,COG5480@2|Bacteria,1RISQ@1224|Proteobacteria,2U9NW@28211|Alphaproteobacteria,3JTM3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF1036) MA20_03870 - - - - - - - - - - - DUF1036 CMS1_k127_2710819_2 1429916.X566_13730 1.931e-166 533.0 COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,2TRFV@28211|Alphaproteobacteria,3JU12@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G Belongs to the pyruvate kinase family pyk - 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PK,PK_C CMS1_k127_2711946_3 1502852.FG94_03124 1.078e-65 229.0 COG0656@1|root,COG0656@2|Bacteria,1MX6S@1224|Proteobacteria,2VNCV@28216|Betaproteobacteria,475IH@75682|Oxalobacteraceae 28216|Betaproteobacteria S Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red CMS1_k127_2711946_1 1187851.A33M_1807 2.381e-230 718.0 COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,2TRPH@28211|Alphaproteobacteria,3FCRC@34008|Rhodovulum 28211|Alphaproteobacteria M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine murA - 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - - EPSP_synthase CMS1_k127_2711946_5 331869.BAL199_21349 2.795e-05 50.0 COG1961@1|root,COG1961@2|Bacteria,1PWCY@1224|Proteobacteria,2TVME@28211|Alphaproteobacteria 28211|Alphaproteobacteria L COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - - - - - - - - - - Recombinase,Resolvase,Zn_ribbon_recom CMS1_k127_2711946_2 981384.AEYW01000003_gene1999 9.05e-135 440.0 COG2114@1|root,COG2114@2|Bacteria 2|Bacteria T Pfam Adenylate and Guanylate cyclase catalytic domain - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - FHA,GAF,GAF_2,Guanylate_cyc,HAMP,PAS,PAS_4,Response_reg CMS1_k127_2711946_4 1380394.JADL01000003_gene5039 4.282e-53 197.0 COG1073@1|root,COG1073@2|Bacteria,1QKK6@1224|Proteobacteria,2TUZ6@28211|Alphaproteobacteria,2JU1J@204441|Rhodospirillales 204441|Rhodospirillales S alpha beta - - - - - - - - - - - - - CMS1_k127_2711946_0 883080.HMPREF9697_01392 3.611e-281 890.0 COG0129@1|root,COG0129@2|Bacteria,1MV4I@1224|Proteobacteria,2TQRW@28211|Alphaproteobacteria,3K2F5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria EG Dehydratase family - - 4.2.1.9 ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R01209,R04441,R05070 RC00468,RC01714 ko00000,ko00001,ko00002,ko01000 - - - ILVD_EDD CMS1_k127_2712785_3 395019.Bmul_5112 5.247e-33 132.0 COG1846@1|root,COG1846@2|Bacteria,1N7G0@1224|Proteobacteria,2VU14@28216|Betaproteobacteria,1K787@119060|Burkholderiaceae 28216|Betaproteobacteria K transcriptional regulator PadR family protein - - - - - - - - - - - - MarR,MarR_2 CMS1_k127_2712785_0 709797.CSIRO_1111 2.024e-233 734.0 COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,2TS87@28211|Alphaproteobacteria,3JQV2@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis ubiB - - ko:K03688 - - - - ko00000 - - - ABC1 CMS1_k127_2712785_1 1187851.A33M_1156 2.958e-114 372.0 COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,2TRWR@28211|Alphaproteobacteria,3FCY6@34008|Rhodovulum 28211|Alphaproteobacteria H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) ubiE - 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 - - - Ubie_methyltran CMS1_k127_2712785_2 1040989.AWZU01000018_gene2731 9.653e-67 231.0 COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,2TS4C@28211|Alphaproteobacteria,3JRJ8@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates fpg - 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS CMS1_k127_2720594_0 1187851.A33M_4106 1.711e-107 357.0 COG2220@1|root,COG2220@2|Bacteria,1NVME@1224|Proteobacteria,2U180@28211|Alphaproteobacteria,3FD37@34008|Rhodovulum 28211|Alphaproteobacteria S Beta-lactamase superfamily domain - - - - - - - - - - - - Lactamase_B_3 CMS1_k127_2720594_2 666684.AfiDRAFT_0416 4.12e-20 101.0 COG4223@1|root,COG4223@2|Bacteria,1MW1G@1224|Proteobacteria,2TVKB@28211|Alphaproteobacteria,3JRNP@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria DZ transferase activity, transferring acyl groups other than amino-acyl groups - - - - - - - - - - - - - CMS1_k127_2720594_1 1211115.ALIQ01000175_gene3657 2.648e-70 241.0 COG0524@1|root,COG0524@2|Bacteria,1MUUC@1224|Proteobacteria,2TS9D@28211|Alphaproteobacteria,3NA09@45404|Beijerinckiaceae 28211|Alphaproteobacteria G pfkB family carbohydrate kinase pfkB - 2.7.1.20,2.7.1.4 ko:K00847,ko:K00856 ko00051,ko00230,ko00500,ko00520,ko01100,map00051,map00230,map00500,map00520,map01100 - R00185,R00760,R00867,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB CMS1_k127_2728655_1 1123393.KB891327_gene394 3.96e-208 676.0 COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,2VI3Z@28216|Betaproteobacteria,1KRJ3@119069|Hydrogenophilales 119069|Hydrogenophilales L ATPase domain of DNA mismatch repair MUTS family - - - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V CMS1_k127_2728655_2 1123393.KB891327_gene395 8.268e-166 522.0 COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,2VIXG@28216|Betaproteobacteria,1KSE9@119069|Hydrogenophilales 119069|Hydrogenophilales G Inositol monophosphatase family - - 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P CMS1_k127_2728655_4 1123392.AQWL01000003_gene377 8.562e-137 438.0 COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,2VI2D@28216|Betaproteobacteria,1KS42@119069|Hydrogenophilales 119069|Hydrogenophilales J SpoU rRNA Methylase family - - - ko:K02533 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase CMS1_k127_2728655_3 292415.Tbd_1162 2.243e-154 488.0 COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,2VH8C@28216|Betaproteobacteria,1KSH1@119069|Hydrogenophilales 119069|Hydrogenophilales E Bacterial transferase hexapeptide (six repeats) - - 2.3.1.30 ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 M00021 R00586 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,SATase_N CMS1_k127_2728655_5 1123393.KB891327_gene398 2.919e-91 301.0 COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,2VRGK@28216|Betaproteobacteria,1KRQI@119069|Hydrogenophilales 119069|Hydrogenophilales K Transcriptional regulator - - - ko:K13643 - - - - ko00000,ko03000 - - - Rrf2 CMS1_k127_2728655_0 1123392.AQWL01000003_gene374 1.225e-250 775.0 COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,2VH91@28216|Betaproteobacteria,1KRGW@119069|Hydrogenophilales 119069|Hydrogenophilales E Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins iscS - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 CMS1_k127_2728655_6 292415.Tbd_1165 1.569e-75 254.0 COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,2VQ2I@28216|Betaproteobacteria,1KT3S@119069|Hydrogenophilales 119069|Hydrogenophilales C NifU-like N terminal domain - - - ko:K04488 - - - - ko00000 - - - NifU_N CMS1_k127_2728655_7 1123393.KB891327_gene401 8.45e-64 218.0 COG0316@1|root,COG0316@2|Bacteria,1RH6T@1224|Proteobacteria,2VSKY@28216|Betaproteobacteria,1KT53@119069|Hydrogenophilales 119069|Hydrogenophilales S Iron-sulphur cluster biosynthesis - - - ko:K13628 - - - - ko00000,ko03016 - - - Fe-S_biosyn CMS1_k127_2739746_2 420324.KI912034_gene2635 3.363e-25 104.0 COG3316@1|root,COG3316@2|Bacteria,1PIDR@1224|Proteobacteria,2V2P0@28211|Alphaproteobacteria,1JYRM@119045|Methylobacteriaceae 28211|Alphaproteobacteria L Transposase and inactivated derivatives - - - - - - - - - - - - - CMS1_k127_2739746_0 1282876.BAOK01000001_gene2986 6.14e-167 532.0 COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,2TSD0@28211|Alphaproteobacteria,4BSFY@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria G Phosphofructokinase pfkA - 2.7.1.11,2.7.1.90 ko:K00850,ko:K21071 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 M00001,M00345 R00756,R00764,R02073,R03236,R03237,R03238,R03239,R04779 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 - - - PFK CMS1_k127_2739746_1 258594.RPA0768 3.823e-27 119.0 COG2801@1|root,COG2801@2|Bacteria,1MZ45@1224|Proteobacteria,2TTG7@28211|Alphaproteobacteria,3JZ1H@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L Integrase core domain - - - - - - - - - - - - HTH_29,HTH_32,rve CMS1_k127_2739746_3 1287116.X734_06070 1.402e-13 79.0 COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,1NKZK@1224|Proteobacteria,2U0EG@28211|Alphaproteobacteria,43K78@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Terminase-like family - - - - - - - - - - - - Terminase_6,Terminase_6C CMS1_k127_2747232_1 319003.Bra1253DRAFT_01256 5.816e-229 715.0 COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,2TS6F@28211|Alphaproteobacteria,3JR45@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function radA - - ko:K04485 - - - - ko00000,ko03400 - - - AAA_25,ATPase,ChlI CMS1_k127_2747232_2 1187851.A33M_1086 3.209e-71 248.0 COG1286@1|root,COG1286@2|Bacteria,1NF4G@1224|Proteobacteria,2TUVR@28211|Alphaproteobacteria,3FDH7@34008|Rhodovulum 28211|Alphaproteobacteria S Colicin V production protein cvpA - - ko:K03558 - - - - ko00000 - - - Colicin_V CMS1_k127_2747232_0 1429916.X566_18900 2.632e-245 763.0 COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,2TR8V@28211|Alphaproteobacteria,3JUSU@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine purF GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase_6,GATase_7,Pribosyltran CMS1_k127_2747699_3 1432050.IE4771_CH03223 4.714e-191 619.0 COG2114@1|root,COG4192@1|root,COG2114@2|Bacteria,COG4192@2|Bacteria,1MV1V@1224|Proteobacteria,2U2BQ@28211|Alphaproteobacteria,4BN8Y@82115|Rhizobiaceae 28211|Alphaproteobacteria T PAS fold - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_cyc,HAMP,PAS_7 CMS1_k127_2747699_5 1120956.JHZK01000001_gene3371 5.078e-163 521.0 COG4663@1|root,COG4663@2|Bacteria,1MUXI@1224|Proteobacteria,2TQVW@28211|Alphaproteobacteria,1JPPC@119043|Rhodobiaceae 28211|Alphaproteobacteria Q Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP,TAT_signal CMS1_k127_2747699_14 398525.KB900701_gene4550 3.9e-11 66.0 COG2114@1|root,COG3899@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,COG3903@2|Bacteria,1MUDT@1224|Proteobacteria,2TQVN@28211|Alphaproteobacteria,3JTQ7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Adenylate and Guanylate cyclase catalytic domain - - - - - - - - - - - - AAA_16,DZR,Guanylate_cyc,SAM_1 CMS1_k127_2747699_8 118166.JH976537_gene3002 1.728e-70 248.0 COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G1QI@1117|Cyanobacteria,1H7BP@1150|Oscillatoriales 1117|Cyanobacteria NU TPR repeat - - - - - - - - - - - - CHAT,TPR_10,TPR_12,TPR_7,TPR_8 CMS1_k127_2747699_11 765912.Thimo_2324 7.857e-55 200.0 COG4566@1|root,COG4566@2|Bacteria,1N6WR@1224|Proteobacteria,1S0TV@1236|Gammaproteobacteria,1WXDV@135613|Chromatiales 135613|Chromatiales K response regulator receiver - - - ko:K13041 ko02020,map02020 M00514 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg CMS1_k127_2747699_9 158500.BV97_04730 1.449e-56 217.0 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TR8X@28211|Alphaproteobacteria,2K0ZS@204457|Sphingomonadales 204457|Sphingomonadales T nitrogen fixation sensor protein fixL - - 2.7.13.3 ko:K14986 ko02020,map02020 M00524 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS CMS1_k127_2747699_1 1207063.P24_10176 8.852e-224 708.0 COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,2TRZQ@28211|Alphaproteobacteria,2JQDW@204441|Rhodospirillales 204441|Rhodospirillales L single-stranded-DNA-specific exonuclease recJ recJ - - ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 CMS1_k127_2747699_7 331869.BAL199_26801 2.67e-142 458.0 COG1494@1|root,COG1494@2|Bacteria,1MUB1@1224|Proteobacteria,2TSPE@28211|Alphaproteobacteria,4BP5E@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria G Bacterial fructose-1,6-bisphosphatase, glpX-encoded glpX - 3.1.3.11,3.1.3.37 ko:K02446,ko:K11532 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00165,M00167 R00762,R01845,R04780 RC00017 ko00000,ko00001,ko00002,ko01000 - - - FBPase_glpX CMS1_k127_2747699_4 269796.Rru_A2410 6.453e-169 540.0 COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,2TQWS@28211|Alphaproteobacteria,2JPAR@204441|Rhodospirillales 204441|Rhodospirillales E homoserine dehydrogenase hom - 1.1.1.3 ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00017,M00018 R01773,R01775 RC00087 ko00000,ko00001,ko00002,ko01000 - - - ACT,Homoserine_dh,NAD_binding_3 CMS1_k127_2747699_2 1316936.K678_01998 2.868e-206 647.0 COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,2TRE3@28211|Alphaproteobacteria,2JPZZ@204441|Rhodospirillales 204441|Rhodospirillales E Aminotransferase - - - ko:K14261 - - - - ko00000,ko01000,ko01007 - - - Aminotran_1_2 CMS1_k127_2747699_13 1122135.KB893166_gene2834 2.352e-24 114.0 COG2885@1|root,COG2885@2|Bacteria,1N2EI@1224|Proteobacteria,2UD4D@28211|Alphaproteobacteria 28211|Alphaproteobacteria M OmpA family - - - - - - - - - - - - OmpA CMS1_k127_2747699_0 1380391.JIAS01000015_gene380 2.497e-279 871.0 COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,2TR7S@28211|Alphaproteobacteria,2JQCH@204441|Rhodospirillales 204441|Rhodospirillales I Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus phbC - - ko:K03821 ko00650,map00650 - R04254 RC00004 ko00000,ko00001,ko01000 - - - Abhydrolase_1,PhaC_N CMS1_k127_2747699_10 1089552.KI911559_gene2542 1.325e-55 200.0 COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,2U5GR@28211|Alphaproteobacteria,2JSBC@204441|Rhodospirillales 204441|Rhodospirillales S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - - - - - - - - - - Hexapep CMS1_k127_2747699_6 1089552.KI911559_gene2543 4.213e-155 497.0 COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,2TRMT@28211|Alphaproteobacteria,2JQ0D@204441|Rhodospirillales 204441|Rhodospirillales E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde argC - 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC CMS1_k127_2747990_0 1380355.JNIJ01000015_gene5977 2.21e-236 737.0 COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,2TR0F@28211|Alphaproteobacteria,3JV0H@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E D-isomer specific 2-hydroxyacid dehydrogenase serA - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C,ACT CMS1_k127_2747990_1 323098.Nwi_2965 1.388e-230 721.0 COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,2TRKY@28211|Alphaproteobacteria,3JQNC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP purA GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 - - - Adenylsucc_synt CMS1_k127_2747990_6 172088.AUGA01000005_gene7725 1.972e-108 366.0 COG0508@1|root,COG4249@1|root,COG0508@2|Bacteria,COG4249@2|Bacteria,1R954@1224|Proteobacteria,2TWG4@28211|Alphaproteobacteria,3JTD6@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Peptidase C14 caspase catalytic subunit p20 - - - - - - - - - - - - - CMS1_k127_2747990_9 1245469.S58_29720 3.129e-21 97.0 COG0818@1|root,COG0818@2|Bacteria,1MZ3Q@1224|Proteobacteria,2U9IE@28211|Alphaproteobacteria,3JYQQ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Recycling of diacylglycerol produced during the turnover of membrane phospholipid dgkA - 2.7.1.107 ko:K00901 ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231 - R02240 RC00002,RC00017 ko00000,ko00001,ko01000 - - - DAGK_prokar CMS1_k127_2747990_2 1089551.KE386572_gene3823 2.558e-185 597.0 COG2194@1|root,COG2194@2|Bacteria 2|Bacteria T sulfuric ester hydrolase activity - - 2.7.8.43 ko:K03760,ko:K19353 ko00540,ko01503,map00540,map01503 M00722 R11555,R11556,R11557 RC00002 ko00000,ko00001,ko00002,ko01000,ko01005 - - - DUF1499,DUF1705,Sulfatase CMS1_k127_2747990_7 1197906.CAJQ02000004_gene2982 6.758e-97 326.0 COG5473@1|root,COG5473@2|Bacteria,1MVRU@1224|Proteobacteria,2TRUD@28211|Alphaproteobacteria,3JT5T@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Predicted integral membrane protein (DUF2189) - - - - - - - - - - - - DUF2189 CMS1_k127_2747990_3 1187851.A33M_0376 1.286e-156 499.0 COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,2TR9Q@28211|Alphaproteobacteria,3FCHM@34008|Rhodovulum 28211|Alphaproteobacteria K Sigma-70 factor, region 1.2 rpoH - - ko:K03089 - - - - ko00000,ko03021 - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r4 CMS1_k127_2747990_5 936455.KI421499_gene5909 6.158e-129 427.0 COG3409@1|root,COG3772@1|root,COG3409@2|Bacteria,COG3772@2|Bacteria,1QW72@1224|Proteobacteria,2UBY3@28211|Alphaproteobacteria,3K0F5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Peptidoglycan-binding domain 1 protein - - - - - - - - - - - - - CMS1_k127_2747990_4 652103.Rpdx1_0198 1.168e-137 445.0 COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,2TSBK@28211|Alphaproteobacteria,3JRC8@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Responsible for synthesis of pseudouridine from uracil rluD GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 CMS1_k127_2747990_8 316055.RPE_0816 4.776e-22 100.0 2ECXJ@1|root,336US@2|Bacteria,1RE34@1224|Proteobacteria,2U7UX@28211|Alphaproteobacteria,3JYR1@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - MA20_04830 - - - - - - - - - - - - CMS1_k127_2747990_10 1298867.AUES01000018_gene4126 4.866e-20 90.0 COG0596@1|root,COG0596@2|Bacteria,1NUT9@1224|Proteobacteria,2TVMS@28211|Alphaproteobacteria,3JUAG@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Putative esterase - - - - - - - - - - - - Abhydrolase_1 CMS1_k127_2749082_0 113395.AXAI01000005_gene4150 2.918e-200 634.0 COG0457@1|root,COG1413@1|root,COG0457@2|Bacteria,COG1413@2|Bacteria,1MX2U@1224|Proteobacteria,2TVI2@28211|Alphaproteobacteria,3JUS1@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Cytochrome c554 and c-prime - - - - - - - - - - - - Cytochrome_C554,HEAT_2,Paired_CXXCH_1,TPR_14,TPR_16,TPR_19,TPR_2,TPR_8 CMS1_k127_2749082_6 323098.Nwi_0999 3.7e-36 139.0 COG0828@1|root,COG0828@2|Bacteria,1MZA1@1224|Proteobacteria,2UC58@28211|Alphaproteobacteria,3JZDH@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Belongs to the bacterial ribosomal protein bS21 family rpsU GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - ko:K02970 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S21 CMS1_k127_2749082_1 316058.RPB_1446 2.761e-154 495.0 COG0026@1|root,COG0026@2|Bacteria,1MU70@1224|Proteobacteria,2TRSV@28211|Alphaproteobacteria,3JR4N@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) purK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp CMS1_k127_2749082_3 1381123.AYOD01000016_gene2667 3.501e-71 244.0 COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,2U58D@28211|Alphaproteobacteria,43JRI@69277|Phyllobacteriaceae 28211|Alphaproteobacteria F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) purE - 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 - - - AIRC CMS1_k127_2749082_5 709797.CSIRO_0363 9.166e-50 184.0 COG2199@1|root,COG2199@2|Bacteria,1Q7FU@1224|Proteobacteria,2TRE7@28211|Alphaproteobacteria,3JTVT@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T diguanylate cyclase - - - - - - - - - - - - GGDEF CMS1_k127_2749082_7 113395.AXAI01000016_gene5004 1.546e-22 101.0 COG5481@1|root,COG5481@2|Bacteria,1NG9U@1224|Proteobacteria,2UFXJ@28211|Alphaproteobacteria,3K07E@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF465) MA20_03740 - - - - - - - - - - - DUF465 CMS1_k127_2749082_8 316056.RPC_3957 7.075e-17 81.0 COG5570@1|root,COG5570@2|Bacteria,1NGRE@1224|Proteobacteria,2UJAX@28211|Alphaproteobacteria,3K16F@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF465) - - - - - - - - - - - - DUF465 CMS1_k127_2749082_4 666684.AfiDRAFT_3069 2.326e-68 244.0 COG1024@1|root,COG1024@2|Bacteria,1Q67Q@1224|Proteobacteria,2U2T5@28211|Alphaproteobacteria,3JRE3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Enoyl-CoA hydratase/isomerase - - - - - - - - - - - - ECH_1 CMS1_k127_2749082_2 1411123.JQNH01000001_gene2548 2.051e-112 364.0 COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,2TR96@28211|Alphaproteobacteria 28211|Alphaproteobacteria IQ COG0318, Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II MA20_29420 - 6.2.1.48 ko:K00666,ko:K02182 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C CMS1_k127_2757912_0 1123237.Salmuc_02987 1.267e-73 255.0 COG0604@1|root,COG0604@2|Bacteria,1MXRX@1224|Proteobacteria,2TRSQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N CMS1_k127_2757912_3 546414.Deide_22680 3.563e-17 88.0 COG4263@1|root,COG4263@2|Bacteria 2|Bacteria C nitrous-oxide reductase activity - - - - - - - - - - - - Cupredoxin_1 CMS1_k127_2757912_1 1318628.MARLIPOL_02715 2.496e-49 184.0 2CDFF@1|root,32RXP@2|Bacteria,1N26W@1224|Proteobacteria,1SUQW@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_2757912_2 1318628.MARLIPOL_02720 5.335e-22 99.0 2F7U0@1|root,34084@2|Bacteria,1NZJ4@1224|Proteobacteria 1318628.MARLIPOL_02720|- - - - - - - - - - - - - - - - CMS1_k127_2759726_0 1304878.AUGD01000001_gene936 5.734e-154 515.0 COG4191@1|root,COG5001@1|root,COG4191@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria,3JRAF@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL,GGDEF,PAS_4,PAS_7,dCache_1 CMS1_k127_2759727_2 1429916.X566_06915 1.93e-89 297.0 COG4674@1|root,COG4674@2|Bacteria,1MUBR@1224|Proteobacteria,2TQVJ@28211|Alphaproteobacteria,3JVGV@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Branched-chain amino acid ATP-binding cassette transporter urtD - - ko:K11962 ko02010,map02010 M00323 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4.4,3.A.1.4.5 - - ABC_tran,BCA_ABC_TP_C CMS1_k127_2759727_1 1187851.A33M_3892 1.176e-111 364.0 COG0410@1|root,COG0410@2|Bacteria,1MU4Z@1224|Proteobacteria,2TS23@28211|Alphaproteobacteria,3FE1C@34008|Rhodovulum 28211|Alphaproteobacteria E ATPases associated with a variety of cellular activities urtE - - ko:K11963 ko02010,map02010 M00323 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4.4,3.A.1.4.5 - - ABC_tran CMS1_k127_2759727_3 398525.KB900701_gene2313 6.812e-86 292.0 COG0829@1|root,COG0829@2|Bacteria,1RABD@1224|Proteobacteria,2U57R@28211|Alphaproteobacteria,3JVJT@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter ureD - - ko:K03190 - - - - ko00000 - - - UreD CMS1_k127_2759727_5 991905.SL003B_0106 1.801e-51 184.0 COG0831@1|root,COG0831@2|Bacteria,1RGXE@1224|Proteobacteria,2U947@28211|Alphaproteobacteria,4BQGV@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria E Urease, gamma subunit ureA - 3.5.1.5 ko:K01430,ko:K14048 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 - R00131 RC02798,RC02806 ko00000,ko00001,ko01000 - - - Urease_beta,Urease_gamma CMS1_k127_2759727_4 1197906.CAJQ02000052_gene4460 2.565e-54 191.0 COG0832@1|root,COG0832@2|Bacteria,1RGW0@1224|Proteobacteria,2U9T4@28211|Alphaproteobacteria,3JYUT@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Belongs to the urease beta subunit family ureB - 3.5.1.5 ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 - R00131 RC02798,RC02806 ko00000,ko00001,ko01000 - - - Urease_beta CMS1_k127_2759727_0 1298867.AUES01000010_gene5746 9.958e-143 454.0 COG0804@1|root,COG0804@2|Bacteria,1MU5P@1224|Proteobacteria,2TSXP@28211|Alphaproteobacteria,3JSTP@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family ureC - 3.5.1.5 ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 - R00131 RC02798,RC02806 ko00000,ko00001,ko01000 - - - Amidohydro_1,Urease_alpha CMS1_k127_2764688_4 1187851.A33M_4108 2.628e-92 306.0 COG0524@1|root,COG0524@2|Bacteria,1MUUC@1224|Proteobacteria,2TS9D@28211|Alphaproteobacteria,3FCY7@34008|Rhodovulum 28211|Alphaproteobacteria G pfkB family carbohydrate kinase pfkB - 2.7.1.20,2.7.1.4 ko:K00847,ko:K00856 ko00051,ko00230,ko00500,ko00520,ko01100,map00051,map00230,map00500,map00520,map01100 - R00185,R00760,R00867,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB CMS1_k127_2764688_3 1187851.A33M_4109 1.03e-131 439.0 COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,2TS44@28211|Alphaproteobacteria,3FCWU@34008|Rhodovulum 28211|Alphaproteobacteria U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane murJ - - ko:K03980 - - - - ko00000,ko01011,ko02000 2.A.66.4 - - MVIN CMS1_k127_2764688_1 883078.HMPREF9695_04846 2.098e-184 589.0 COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,2TQZX@28211|Alphaproteobacteria,3JT4N@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Tryptophanyl-tRNA synthetase trpS - 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1b CMS1_k127_2764688_9 1197906.CAJQ02000034_gene2673 7.395e-55 199.0 COG0589@1|root,COG0589@2|Bacteria,1R9XB@1224|Proteobacteria,2U59E@28211|Alphaproteobacteria,3JTIW@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Universal stress protein family MA20_23830 - - - - - - - - - - - Usp CMS1_k127_2764688_5 1038859.AXAU01000004_gene4659 1.259e-88 301.0 COG0694@1|root,COG0694@2|Bacteria,1MVQ1@1224|Proteobacteria,2TUD1@28211|Alphaproteobacteria,3JR1N@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O Scaffold protein Nfu/NifU N terminal nifU - - - - - - - - - - - Nfu_N,NifU CMS1_k127_2764688_6 1187851.A33M_4116 4.733e-79 271.0 COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,2TTM2@28211|Alphaproteobacteria,3FDCB@34008|Rhodovulum 28211|Alphaproteobacteria O Glycoprotease family yeaZ - 2.3.1.234 ko:K01409,ko:K14742 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 CMS1_k127_2764688_11 196490.AUEZ01000027_gene1759 8.497e-40 161.0 COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,2UF5C@28211|Alphaproteobacteria,3JX20@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K FR47-like protein rimI - 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1,Acetyltransf_10 CMS1_k127_2764688_8 1187851.A33M_4118 2.723e-66 229.0 COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,2U6ZS@28211|Alphaproteobacteria,3FEAI@34008|Rhodovulum 28211|Alphaproteobacteria K Ferric uptake regulator family fur - - ko:K03711 - - - - ko00000,ko03000 - - - FUR CMS1_k127_2764688_7 1131814.JAFO01000001_gene4942 1.221e-73 257.0 COG0204@1|root,COG0204@2|Bacteria,1N2DG@1224|Proteobacteria,2TT8Q@28211|Alphaproteobacteria,3EY47@335928|Xanthobacteraceae 28211|Alphaproteobacteria I Phosphate acyltransferases plsC - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase CMS1_k127_2764688_0 1411123.JQNH01000001_gene3461 3.997e-193 613.0 COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,2TQN6@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine miaB - 2.8.4.3 ko:K06168 - - R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 - - - Radical_SAM,TRAM,UPF0004 CMS1_k127_2764688_2 1429916.X566_10205 1.425e-168 535.0 COG1702@1|root,COG1702@2|Bacteria,1MVDV@1224|Proteobacteria,2TRV3@28211|Alphaproteobacteria,3JS5Z@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T PhoH-like protein phoH - - ko:K06217 - - - - ko00000 - - - PhoH CMS1_k127_2764688_10 1297863.APJF01000016_gene4238 4.654e-45 169.0 COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,2UBXV@28211|Alphaproteobacteria,3JWAC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ybeY - - ko:K07042 - - - - ko00000,ko03009 - - - UPF0054 CMS1_k127_2764688_12 1304877.KI519399_gene2432 4.885e-27 113.0 COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,2TVFA@28211|Alphaproteobacteria,3JSH4@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Transporter associated domain tlyC - - ko:K06189 - - - - ko00000,ko02000 9.A.40.1.2 - - CBS,CorC_HlyC CMS1_k127_2764773_0 639283.Snov_1877 4.496e-139 447.0 COG2607@1|root,COG2607@2|Bacteria,1MVMX@1224|Proteobacteria,2TTFE@28211|Alphaproteobacteria,3EY0G@335928|Xanthobacteraceae 28211|Alphaproteobacteria S Protein of unknown function (DUF815) MA20_41470 - - ko:K06923 - - - - ko00000 - - - DUF815 CMS1_k127_2764773_3 1089551.KE386572_gene1513 2.186e-95 319.0 COG2114@1|root,COG2114@2|Bacteria,1N6I7@1224|Proteobacteria,2U3M0@28211|Alphaproteobacteria 28211|Alphaproteobacteria T Adenylate cyclase, family 3 (some proteins contain HAMP domain) - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - DUF4242,Guanylate_cyc CMS1_k127_2764773_2 1429916.X566_21210 5.033e-107 361.0 COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,1QV29@1224|Proteobacteria,2TW8Q@28211|Alphaproteobacteria,3JTS0@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Lysin motif lysM - - - - - - - - - - - LysM,Peptidase_M23 CMS1_k127_2764773_4 1187851.A33M_2315 1.258e-89 300.0 COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,2TVCY@28211|Alphaproteobacteria,3FD11@34008|Rhodovulum 28211|Alphaproteobacteria J Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins pcm - 2.1.1.77 ko:K00573 - - - - ko00000,ko01000 - - - PCMT CMS1_k127_2764773_6 1187851.A33M_2316 5.361e-33 135.0 COG0784@1|root,COG0784@2|Bacteria,1N70P@1224|Proteobacteria,2UF5P@28211|Alphaproteobacteria 28211|Alphaproteobacteria T Response regulator receiver MA20_41525 - - - - - - - - - - - Response_reg CMS1_k127_2764773_7 196490.AUEZ01000007_gene5083 1.14e-05 47.0 COG1028@1|root,COG1028@2|Bacteria,1MVT2@1224|Proteobacteria,2TQKU@28211|Alphaproteobacteria,3JS01@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria IQ Enoyl-(Acyl carrier protein) reductase fixR - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 CMS1_k127_2764773_1 1187851.A33M_2317 5.633e-116 378.0 COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,2TQXZ@28211|Alphaproteobacteria,3FD5Y@34008|Rhodovulum 28211|Alphaproteobacteria S Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates surE - 3.1.3.5 ko:K03787 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - SurE CMS1_k127_2764773_5 78245.Xaut_4404 1.011e-74 252.0 COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,2TR4T@28211|Alphaproteobacteria,3EYPA@335928|Xanthobacteraceae 28211|Alphaproteobacteria J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) serS - 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Seryl_tRNA_N,tRNA-synt_2b CMS1_k127_2771820_6 441620.Mpop_4038 2.824e-34 135.0 COG0762@1|root,COG0762@2|Bacteria,1N73Q@1224|Proteobacteria,2UFZR@28211|Alphaproteobacteria,1JVBJ@119045|Methylobacteriaceae 28211|Alphaproteobacteria S YGGT family MA20_25225 - - ko:K02221 - - - - ko00000,ko02044 - - - YGGT CMS1_k127_2771820_7 595536.ADVE02000001_gene3829 3.4e-28 116.0 COG1872@1|root,COG1872@2|Bacteria,1N6V2@1224|Proteobacteria,2UF67@28211|Alphaproteobacteria,36YSU@31993|Methylocystaceae 28211|Alphaproteobacteria S DUF167 MA20_25230 - - ko:K09131 - - - - ko00000 - - - DUF167 CMS1_k127_2771820_2 316058.RPB_0108 1.147e-126 415.0 COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,2TRZZ@28211|Alphaproteobacteria,3JQPP@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate folD GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 - - - THF_DHG_CYH,THF_DHG_CYH_C CMS1_k127_2771820_3 323097.Nham_0611 2.741e-93 308.0 COG1247@1|root,COG1247@2|Bacteria,1QU6B@1224|Proteobacteria,2TW1F@28211|Alphaproteobacteria,3JSZM@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M FR47-like protein - - - - - - - - - - - - Acetyltransf_1,FR47 CMS1_k127_2771820_0 1040989.AWZU01000033_gene3573 0.0 1037.0 COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,2TR63@28211|Alphaproteobacteria,3JTCG@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T GTP-binding protein TypA typA GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840 - ko:K06207 - - - - ko00000 - - - EFG_C,GTP_EFTU,GTP_EFTU_D2 CMS1_k127_2771820_4 566466.NOR53_1646 1.062e-51 194.0 COG0625@1|root,COG0625@2|Bacteria,1R6UY@1224|Proteobacteria,1RY70@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Glutathione S-transferase, C-terminal domain - - - - - - - - - - - - GST_C,GST_C_2,GST_N_3 CMS1_k127_2771820_1 1038867.AXAY01000009_gene5752 4.82e-147 475.0 COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,1MY9R@1224|Proteobacteria,2TTFW@28211|Alphaproteobacteria,3JXFM@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Peptidase family M50 - - - ko:K06402 - - - - ko00000,ko01000,ko01002 - - - CBS,Peptidase_M50 CMS1_k127_2771820_5 1297863.APJF01000016_gene4347 2.856e-42 158.0 COG2154@1|root,COG2154@2|Bacteria,1MZ5Q@1224|Proteobacteria,2UBWN@28211|Alphaproteobacteria,3JZHK@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H pterin-4-alpha-carbinolamine dehydratase phhB - 4.2.1.96 ko:K01724 ko00790,map00790 - R04734 RC01208 ko00000,ko00001,ko01000,ko04147 - - - Pterin_4a CMS1_k127_2771820_8 652103.Rpdx1_0241 3.206e-17 83.0 COG3339@1|root,COG3339@2|Bacteria,1MZR5@1224|Proteobacteria,2UCIB@28211|Alphaproteobacteria,3JYQE@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF1232) MA20_25305 - - - - - - - - - - - DUF1232 CMS1_k127_2772006_1 1187851.A33M_1829 7.296e-100 327.0 COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,2TQNE@28211|Alphaproteobacteria,3FCH9@34008|Rhodovulum 28211|Alphaproteobacteria F Prokaryotic glutathione synthetase, N-terminal domain gshB GO:0003674,GO:0003824,GO:0004363,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0019184,GO:0034641,GO:0042398,GO:0043043,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044424,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901564,GO:1901566,GO:1901576 6.3.2.3 ko:K01920 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00497,R10994 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - - GSH-S_ATP,GSH-S_N CMS1_k127_2772006_0 1040989.AWZU01000042_gene97 8.531e-260 808.0 COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,2TQU6@28211|Alphaproteobacteria,3JVC0@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O Magnesium chelatase, subunit ChlI C-terminal comM - - ko:K07391 - - - - ko00000 - - - ChlI,Mg_chelatase,Mg_chelatase_C CMS1_k127_2772006_3 1038867.AXAY01000037_gene360 1.881e-05 53.0 2A6SJ@1|root,30VKT@2|Bacteria,1RAEW@1224|Proteobacteria,2U654@28211|Alphaproteobacteria,3JYG8@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_2772006_2 936455.KI421499_gene6629 4.516e-36 143.0 COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2TWPZ@28211|Alphaproteobacteria,3JTJD@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,PAS,PAS_4,PAS_8,Response_reg CMS1_k127_2774754_10 765698.Mesci_4428 1.917e-31 136.0 COG1832@1|root,COG1832@2|Bacteria,1N03D@1224|Proteobacteria,2TUIY@28211|Alphaproteobacteria,43HG8@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S CoA-binding protein yccU GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K06929 - - - - ko00000 - - - CoA_binding_2 CMS1_k127_2774754_8 404589.Anae109_3650 1.657e-61 233.0 COG3576@1|root,COG3576@2|Bacteria,1NBWC@1224|Proteobacteria,42X9X@68525|delta/epsilon subdivisions,2X3AH@28221|Deltaproteobacteria,2YV4Q@29|Myxococcales 28221|Deltaproteobacteria S Pfam:Pyridox_oxidase - - - ko:K07006 - - - - ko00000 - - - Putative_PNPOx CMS1_k127_2774754_3 883078.HMPREF9695_02081 2.963e-114 376.0 COG1024@1|root,COG1024@2|Bacteria,1MUJ7@1224|Proteobacteria,2TTMB@28211|Alphaproteobacteria,3JRTP@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I enoyl-CoA hydratase MA20_36945 - - - - - - - - - - - ECH_1 CMS1_k127_2774754_11 666684.AfiDRAFT_0399 1.301e-29 121.0 2C3CF@1|root,32RRR@2|Bacteria,1MZUG@1224|Proteobacteria,2UC1Q@28211|Alphaproteobacteria,3K03D@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF3175) - - - - - - - - - - - - DUF3175 CMS1_k127_2774754_9 1187851.A33M_0672 5.533e-42 158.0 COG2050@1|root,COG2050@2|Bacteria,1MZRJ@1224|Proteobacteria,2U9BM@28211|Alphaproteobacteria,3FD9B@34008|Rhodovulum 28211|Alphaproteobacteria Q Thioesterase superfamily MA20_36950 - - - - - - - - - - - 4HBT CMS1_k127_2774754_5 1187851.A33M_0671 1.588e-78 268.0 COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,2U5FM@28211|Alphaproteobacteria,3FD10@34008|Rhodovulum 28211|Alphaproteobacteria J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly rplM GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02871 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L13 CMS1_k127_2774754_6 1040989.AWZU01000003_gene6660 2.039e-75 255.0 COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,2U5B5@28211|Alphaproteobacteria,3JR49@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Belongs to the universal ribosomal protein uS9 family rpsI GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02996 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S9 CMS1_k127_2774754_4 1187851.A33M_3213 2.489e-98 339.0 COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,2TRAF@28211|Alphaproteobacteria 28211|Alphaproteobacteria T GGDEF domain MA20_36965 - - - - - - - - - - - GGDEF CMS1_k127_2774754_0 1187851.A33M_0499 1.361e-280 867.0 COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,2TSCR@28211|Alphaproteobacteria,3FCI2@34008|Rhodovulum 28211|Alphaproteobacteria E Glutamine synthetase, catalytic domain glnA - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C,Gln-synt_N CMS1_k127_2774754_7 384765.SIAM614_15350 1.275e-61 214.0 COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2U73Z@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Belongs to the P(II) protein family glnB GO:0003674,GO:0006808,GO:0008150,GO:0030234,GO:0050789,GO:0050790,GO:0065007,GO:0065009,GO:0098772 - ko:K04751 ko02020,map02020 - - - ko00000,ko00001 - - - P-II CMS1_k127_2774754_1 883080.HMPREF9697_00534 6.616e-177 569.0 COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,2TT58@28211|Alphaproteobacteria,3JU34@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD - - - - - - - - - - - Carb_kinase,YjeF_N CMS1_k127_2774754_2 1297569.MESS2_730265 2.55e-116 392.0 COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,2TQXH@28211|Alphaproteobacteria,43NR1@69277|Phyllobacteriaceae 28211|Alphaproteobacteria Q Multicopper oxidase - - - - - - - - - - - - Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3 CMS1_k127_2774754_13 1120963.KB894491_gene1107 1.14e-08 57.0 2DE24@1|root,2ZK69@2|Bacteria,1P9N5@1224|Proteobacteria,1SU0Y@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_2774754_12 1125973.JNLC01000016_gene2780 4.273e-27 111.0 COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,2TS8W@28211|Alphaproteobacteria,3JSQU@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase tig GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K03545 - - - - ko00000 - - - FKBP_C,Trigger_C,Trigger_N CMS1_k127_2775493_13 504832.OCAR_5461 5.087e-31 124.0 COG3545@1|root,COG3545@2|Bacteria,1RDB7@1224|Proteobacteria,2U607@28211|Alphaproteobacteria,3JZMZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Serine hydrolase - - - ko:K07002 - - - - ko00000 - - - Ser_hydrolase CMS1_k127_2775493_0 1429916.X566_24070 5.3e-239 743.0 COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,2TQUE@28211|Alphaproteobacteria,3JSWI@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily purB GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 - - - ADSL_C,Lyase_1 CMS1_k127_2775493_9 1429916.X566_24065 4.423e-105 347.0 COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,2TQKR@28211|Alphaproteobacteria,3JR4Q@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G Belongs to the ribulose-phosphate 3-epimerase family rpe - 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - - Ribul_P_3_epim CMS1_k127_2775493_12 1197906.CAJQ02000004_gene3041 2.091e-68 247.0 COG0385@1|root,COG0385@2|Bacteria,1MVXH@1224|Proteobacteria,2TTE0@28211|Alphaproteobacteria,3JTHY@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Bile acid - - - ko:K03453 - - - - ko00000 2.A.28 - - SBF CMS1_k127_2775493_4 1168059.KB899087_gene1132 2.189e-140 458.0 COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,2TSQI@28211|Alphaproteobacteria,3EZ3A@335928|Xanthobacteraceae 28211|Alphaproteobacteria E FAD dependent oxidoreductase MA20_29210 - 1.4.5.1 ko:K00285 ko00360,map00360 - R01374,R09493 RC00006,RC00025 ko00000,ko00001,ko01000 - - - DAO CMS1_k127_2775493_6 1038859.AXAU01000016_gene6862 2.509e-136 441.0 COG3191@1|root,COG3191@2|Bacteria,1MWDP@1224|Proteobacteria,2TRDC@28211|Alphaproteobacteria,3JUMH@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria EQ Peptidase family S58 dmpA - 3.4.11.19 ko:K01266 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S58 CMS1_k127_2775493_11 1429916.X566_24030 5.377e-98 328.0 COG0785@1|root,COG0785@2|Bacteria,1RCP7@1224|Proteobacteria,2TSAI@28211|Alphaproteobacteria,3JS7I@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O cytochrome c biogenesis protein MA20_17170 - - ko:K06196 - - - - ko00000,ko02000 5.A.1.2 - - DsbD CMS1_k127_2775493_2 113395.AXAI01000018_gene4788 2.656e-169 539.0 COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,2TT0T@28211|Alphaproteobacteria,3JR5R@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Receptor family ligand binding region livK - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 CMS1_k127_2775493_14 1211115.ALIQ01000095_gene278 1.36e-30 128.0 2C07J@1|root,32SWS@2|Bacteria,1N0NW@1224|Proteobacteria,2UCVR@28211|Alphaproteobacteria,3NBR9@45404|Beijerinckiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_2775493_8 639283.Snov_2132 8.082e-122 396.0 COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2TR61@28211|Alphaproteobacteria,3EYUN@335928|Xanthobacteraceae 28211|Alphaproteobacteria E ATPases associated with a variety of cellular activities livF - - ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran CMS1_k127_2775493_7 426355.Mrad2831_2251 1.512e-132 428.0 COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,2TQK1@28211|Alphaproteobacteria,1JRX6@119045|Methylobacteriaceae 28211|Alphaproteobacteria E PFAM ABC transporter braF GO:0003333,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0015711,GO:0015803,GO:0015804,GO:0015807,GO:0015808,GO:0015818,GO:0015829,GO:0015849,GO:0015893,GO:0032328,GO:0034220,GO:0042221,GO:0042493,GO:0042940,GO:0042941,GO:0043090,GO:0046942,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903805,GO:1903806,GO:1903825,GO:1905039 3.5.4.44 ko:K01995,ko:K15783 ko00260,ko01100,ko02010,ko02024,map00260,map01100,map02010,map02024 M00237 R09800 RC02661 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C CMS1_k127_2775493_1 1429916.X566_24005 1.215e-175 561.0 COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,2TSJQ@28211|Alphaproteobacteria,3JQQ9@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Belongs to the binding-protein-dependent transport system permease family livM - - ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2,DUF3382 CMS1_k127_2775493_3 883078.HMPREF9695_02615 4.914e-151 484.0 COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,2TSDS@28211|Alphaproteobacteria,3JT5S@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Belongs to the binding-protein-dependent transport system permease family livH GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0043090,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098713,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 CMS1_k127_2775493_10 1187851.A33M_4365 3.792e-104 346.0 COG2207@1|root,COG2207@2|Bacteria,1MXDJ@1224|Proteobacteria,2U1T4@28211|Alphaproteobacteria,3FDD9@34008|Rhodovulum 28211|Alphaproteobacteria K helix_turn_helix, arabinose operon control protein pobR - - ko:K18954 - - - - ko00000,ko03000 - - - AraC_binding,HTH_18 CMS1_k127_2775493_5 491916.RHECIAT_PC0000523 1.43e-137 443.0 COG0655@1|root,COG0655@2|Bacteria,1MX6A@1224|Proteobacteria,2TU75@28211|Alphaproteobacteria,4B7D5@82115|Rhizobiaceae 28211|Alphaproteobacteria S NADPH-dependent FMN reductase - - - - - - - - - - - - FMN_red CMS1_k127_2800906_9 935261.JAGL01000009_gene1226 1.939e-61 215.0 COG0410@1|root,COG0410@2|Bacteria,1MUFR@1224|Proteobacteria,2TUBS@28211|Alphaproteobacteria,43QXB@69277|Phyllobacteriaceae 28211|Alphaproteobacteria E ATPases associated with a variety of cellular activities - - - ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran CMS1_k127_2800906_4 1380355.JNIJ01000007_gene3233 2.595e-154 492.0 COG0726@1|root,COG0726@2|Bacteria,1MV3V@1224|Proteobacteria,2TR0I@28211|Alphaproteobacteria,3JWN0@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G Polysaccharide deacetylase - - - - - - - - - - - - Polysacc_deac_1 CMS1_k127_2800906_16 1280953.HOC_07967 5.376e-13 74.0 COG2827@1|root,COG2827@2|Bacteria,1MZME@1224|Proteobacteria,2UCNX@28211|Alphaproteobacteria,43YEU@69657|Hyphomonadaceae 28211|Alphaproteobacteria L PFAM Excinuclease ABC C subunit domain protein - - - ko:K07461 - - - - ko00000 - - - GIY-YIG CMS1_k127_2800906_3 1380355.JNIJ01000007_gene3231 1.799e-154 491.0 COG0726@1|root,COG0726@2|Bacteria,1MV3V@1224|Proteobacteria,2TR0I@28211|Alphaproteobacteria,3JWN0@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G Polysaccharide deacetylase - - - - - - - - - - - - Polysacc_deac_1 CMS1_k127_2800906_12 985054.JQEZ01000004_gene966 2.218e-44 163.0 COG1917@1|root,COG1917@2|Bacteria,1MZD8@1224|Proteobacteria,2UBX5@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Cupin domain - - - - - - - - - - - - Cupin_2 CMS1_k127_2800906_6 1121106.JQKB01000015_gene5830 2.034e-108 359.0 COG0726@1|root,COG0726@2|Bacteria,1MV3V@1224|Proteobacteria,2TR0I@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Polysaccharide deacetylase - - - - - - - - - - - - Polysacc_deac_1 CMS1_k127_2800906_2 1187851.A33M_3273 1.42e-154 502.0 COG0154@1|root,COG0154@2|Bacteria,1MU51@1224|Proteobacteria,2TS1E@28211|Alphaproteobacteria,3FCZP@34008|Rhodovulum 28211|Alphaproteobacteria J Amidase - - 3.5.1.4 ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 - R02540,R03096,R03180,R03909,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000 - - - Amidase CMS1_k127_2800906_7 438753.AZC_4639 2.051e-95 317.0 COG0461@1|root,COG0461@2|Bacteria,1MVP7@1224|Proteobacteria,2TTSB@28211|Alphaproteobacteria,3F191@335928|Xanthobacteraceae 28211|Alphaproteobacteria F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) pyrE - 2.4.2.10 ko:K00762 ko00240,ko01100,map00240,map01100 M00051 R01870 RC00611 ko00000,ko00001,ko00002,ko01000 - - - Pribosyltran CMS1_k127_2800906_10 717785.HYPMC_3364 1.342e-48 187.0 COG1638@1|root,COG1638@2|Bacteria,1RFVB@1224|Proteobacteria,2U7FE@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Bacterial extracellular solute-binding protein, family 7 - - - ko:K21395 - - - - ko00000,ko02000 2.A.56.1 - - DctP CMS1_k127_2800906_14 1123060.JONP01000001_gene1514 1.645e-16 88.0 COG3090@1|root,COG3090@2|Bacteria,1RJ0S@1224|Proteobacteria,2VERE@28211|Alphaproteobacteria,2JY43@204441|Rhodospirillales 204441|Rhodospirillales G COG3090 TRAP-type C4-dicarboxylate transport system, small permease component - - - - - - - - - - - - DctQ CMS1_k127_2800906_5 1123060.JONP01000001_gene1515 3.701e-121 402.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQW5@28211|Alphaproteobacteria,2JQGA@204441|Rhodospirillales 204441|Rhodospirillales G COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - ko:K11690 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.56.1 - - DctM CMS1_k127_2800906_17 768671.ThimaDRAFT_2451 1.454e-06 55.0 COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,1S720@1236|Gammaproteobacteria 1236|Gammaproteobacteria K Adenylate cyclase - - - - - - - - - - - - TPR_11,TPR_16,TPR_19,TPR_2,TPR_8,Trans_reg_C CMS1_k127_2800906_11 1297863.APJF01000012_gene1559 2.12e-46 172.0 COG1917@1|root,COG1917@2|Bacteria,1NNBT@1224|Proteobacteria,2U1PR@28211|Alphaproteobacteria,3JR2X@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Cupin 2, conserved barrel domain protein - - - - - - - - - - - - Cupin_2 CMS1_k127_2800906_15 1168059.KB899087_gene3034 4.942e-15 77.0 COG3197@1|root,COG3197@2|Bacteria,1NG90@1224|Proteobacteria,2UJFJ@28211|Alphaproteobacteria,3F063@335928|Xanthobacteraceae 28211|Alphaproteobacteria P Cytochrome oxidase maturation protein cbb3-type fixS - - - - - - - - - - - FixS CMS1_k127_2800906_0 864069.MicloDRAFT_00022710 1.619e-273 858.0 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2TR80@28211|Alphaproteobacteria,1JS3H@119045|Methylobacteriaceae 28211|Alphaproteobacteria P ATPase, P-type (transporting), HAD superfamily, subfamily IC fixI GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.4 ko:K01533 - - R00086 RC00002 ko00000,ko01000 3.A.3.5 - - E1-E2_ATPase,HMA,Hydrolase CMS1_k127_2800906_13 1131814.JAFO01000001_gene925 2.088e-38 156.0 COG5456@1|root,COG5456@2|Bacteria,1RHKI@1224|Proteobacteria,2U9GB@28211|Alphaproteobacteria,3EZY5@335928|Xanthobacteraceae 28211|Alphaproteobacteria P FixH fixH - - - - - - - - - - - FixH CMS1_k127_2800906_1 1125973.JNLC01000010_gene1621 2.636e-225 707.0 COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,2TRYB@28211|Alphaproteobacteria,3JQTF@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C 4Fe-4S ferredoxin, iron-sulfur binding domain ccoG GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - Fer4_18,Fer4_5,FixG_C CMS1_k127_2800906_8 1125973.JNLC01000010_gene1620 1.282e-85 286.0 COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,2TQW1@28211|Alphaproteobacteria,3JQXG@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex ccoP - - ko:K00406 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - Cytochrome_CBB3,FixP_N CMS1_k127_2837654_0 349163.Acry_0002 1.619e-127 415.0 COG0627@1|root,COG0627@2|Bacteria,1MUID@1224|Proteobacteria,2TQSM@28211|Alphaproteobacteria,2JQF9@204441|Rhodospirillales 204441|Rhodospirillales S Serine hydrolase involved in the detoxification of formaldehyde - - 3.1.2.12 ko:K01070 ko00680,ko01120,ko01200,map00680,map01120,map01200 - R00527 RC00167,RC00320 ko00000,ko00001,ko01000 - CE1 - Esterase CMS1_k127_2857985_2 648757.Rvan_0577 2.592e-55 197.0 COG1136@1|root,COG1136@2|Bacteria,1RA1K@1224|Proteobacteria,2U7CA@28211|Alphaproteobacteria,3N811@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria V ATPases associated with a variety of cellular activities bceA - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran CMS1_k127_2857985_0 717785.HYPMC_0711 1.651e-173 561.0 COG0577@1|root,COG0577@2|Bacteria,1MVN1@1224|Proteobacteria,2TTEF@28211|Alphaproteobacteria,3N77U@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria V FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD CMS1_k127_2857985_1 189753.AXAS01000073_gene7670 1.492e-92 316.0 COG4191@1|root,COG4191@2|Bacteria,1MXK6@1224|Proteobacteria,2U4TI@28211|Alphaproteobacteria,3JX1R@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T MASE1 - - - - - - - - - - - - HATPase_c,MASE1 CMS1_k127_2859479_7 1380394.JADL01000007_gene4470 1.336e-110 362.0 COG2057@1|root,COG2057@2|Bacteria,1MY3S@1224|Proteobacteria,2TUZ8@28211|Alphaproteobacteria,2JS0R@204441|Rhodospirillales 204441|Rhodospirillales I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit - - 2.8.3.12 ko:K01040 ko00643,ko00650,ko01120,map00643,map00650,map01120 - R04000,R05509 RC00012,RC00131,RC00137 ko00000,ko00001,ko01000 - - - CoA_trans CMS1_k127_2859479_1 639283.Snov_0185 1.219e-181 574.0 COG0673@1|root,COG0673@2|Bacteria 2|Bacteria S inositol 2-dehydrogenase activity - - - ko:K18106 ko00040,ko01100,map00040,map01100 M00630 R07676,R10565 RC00108 ko00000,ko00001,ko00002,ko01000 - - - GFO_IDH_MocA,GFO_IDH_MocA_C CMS1_k127_2859479_8 1230476.C207_04853 1.517e-86 299.0 COG5330@1|root,COG5330@2|Bacteria,1R3VY@1224|Proteobacteria,2TUQ8@28211|Alphaproteobacteria,3JWA9@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Uncharacterised protein conserved in bacteria (DUF2336) - - - - - - - - - - - - DUF2336 CMS1_k127_2859479_3 113395.AXAI01000009_gene2454 1.304e-148 489.0 COG0457@1|root,COG0457@2|Bacteria,1MUZK@1224|Proteobacteria,2TS0U@28211|Alphaproteobacteria,3JRSC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - - - - - - - - - - Glyco_transf_9,TPR_1,TPR_11,TPR_12,TPR_16,TPR_19,TPR_2,TPR_4,TPR_8 CMS1_k127_2859479_5 1123060.JONP01000028_gene3690 1.565e-120 403.0 COG2055@1|root,COG2055@2|Bacteria,1MWQY@1224|Proteobacteria,2TR37@28211|Alphaproteobacteria,2JQIF@204441|Rhodospirillales 204441|Rhodospirillales C Belongs to the LDH2 MDH2 oxidoreductase family - - - - - - - - - - - - Ldh_2 CMS1_k127_2859479_6 1125973.JNLC01000011_gene580 1.49e-116 385.0 COG2159@1|root,COG2159@2|Bacteria,1R5PG@1224|Proteobacteria,2U2G9@28211|Alphaproteobacteria,3JWBY@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Amidohydrolase - - 4.1.1.45 ko:K03392 ko00380,ko01100,map00380,map01100 M00038 R04323 RC00779 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_2 CMS1_k127_2859479_0 1123060.JONP01000011_gene3068 2.311e-219 706.0 COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TQMW@28211|Alphaproteobacteria 28211|Alphaproteobacteria C COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs - - 1.2.5.3 ko:K03520 - - R11168 RC02800 ko00000,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 CMS1_k127_2859479_4 1280948.HY36_06075 5.865e-142 466.0 COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,2TURI@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q Multi-copper - - 1.3.3.5 ko:K08100 ko00860,ko01110,map00860,map01110 - R02394 RC01983 ko00000,ko00001,ko01000 - - - Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3 CMS1_k127_2859479_2 1121861.KB899926_gene2664 1.197e-174 554.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,2JRDI@204441|Rhodospirillales 204441|Rhodospirillales C Aldehyde dehydrogenase family - - 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh CMS1_k127_2866244_14 1187851.A33M_4106 3.523e-09 57.0 COG2220@1|root,COG2220@2|Bacteria,1NVME@1224|Proteobacteria,2U180@28211|Alphaproteobacteria,3FD37@34008|Rhodovulum 28211|Alphaproteobacteria S Beta-lactamase superfamily domain - - - - - - - - - - - - Lactamase_B_3 CMS1_k127_2866244_11 1197906.CAJQ02000034_gene2677 2.221e-20 94.0 2ENEC@1|root,33G1V@2|Bacteria,1RDM6@1224|Proteobacteria,2U7B6@28211|Alphaproteobacteria,3JZ0W@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - MA20_23800 - - - - - - - - - - - - CMS1_k127_2866244_6 1122207.MUS1_15245 1.392e-150 488.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RQH6@1236|Gammaproteobacteria,1XN38@135619|Oceanospirillales 135619|Oceanospirillales G Tripartite ATP-independent periplasmic transporter, DctM component - - - - - - - - - - - - DctM CMS1_k127_2866244_9 1100720.ALKN01000035_gene953 3.572e-27 119.0 COG4665@1|root,COG4665@2|Bacteria,1RBTR@1224|Proteobacteria 1224|Proteobacteria Q Tripartite ATP-independent periplasmic transporters, DctQ component - - - - - - - - - - - - DctQ CMS1_k127_2866244_8 1469245.JFBG01000011_gene805 7.257e-95 323.0 COG1638@1|root,COG1638@2|Bacteria,1MUJY@1224|Proteobacteria,1S63M@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP CMS1_k127_2866244_2 1197906.CAJQ02000023_gene2325 4.328e-205 647.0 COG4638@1|root,COG4638@2|Bacteria,1MX47@1224|Proteobacteria,2TV03@28211|Alphaproteobacteria,3JV2C@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P Rieske [2Fe-2S] domain MA20_22525 - - - - - - - - - - - Aromatic_hydrox,Rieske CMS1_k127_2866244_3 196490.AUEZ01000122_gene2585 2.182e-203 643.0 COG0174@1|root,COG0174@2|Bacteria,1MU6V@1224|Proteobacteria,2VG5K@28211|Alphaproteobacteria,3JTG6@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Belongs to the glutamine synthetase family MA20_22530 - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C,Gln-synt_N_2 CMS1_k127_2866244_7 113395.AXAI01000013_gene6896 3.382e-110 366.0 COG0596@1|root,COG0596@2|Bacteria,1NJ2B@1224|Proteobacteria,2TR54@28211|Alphaproteobacteria,3JQWT@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Alpha/beta hydrolase family MA20_20400 - 3.4.11.5 ko:K01259 ko00330,map00330 - R00135 - ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_1 CMS1_k127_2866244_13 626418.bglu_1g17740 1.137e-11 71.0 COG5487@1|root,COG5487@2|Bacteria,1NGAH@1224|Proteobacteria,2VXNN@28216|Betaproteobacteria,1KAB0@119060|Burkholderiaceae 28216|Betaproteobacteria S UPF0391 membrane protein - - - - - - - - - - - - DUF1328 CMS1_k127_2866244_0 1429916.X566_07945 0.0 1285.0 COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,2TRBK@28211|Alphaproteobacteria,3JQQ2@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrB - 5.99.1.3 ko:K02470 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim CMS1_k127_2866244_5 316055.RPE_0003 2.353e-154 496.0 COG1195@1|root,COG1195@2|Bacteria,1MX8N@1224|Proteobacteria,2TQRD@28211|Alphaproteobacteria,3JS71@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP recF - - ko:K03629 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - AAA_21,AAA_23,SMC_N CMS1_k127_2866244_4 1429916.X566_07935 2.389e-201 633.0 COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,2TSRZ@28211|Alphaproteobacteria,3JUE8@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria dnaN - 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 CMS1_k127_2866244_1 1230476.C207_03874 1.289e-231 728.0 COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,2TT03@28211|Alphaproteobacteria,3JSPI@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N CMS1_k127_2866244_10 1502851.FG93_02616 1.865e-25 107.0 COG0268@1|root,COG0268@2|Bacteria,1MZ94@1224|Proteobacteria,2UC42@28211|Alphaproteobacteria,3K06W@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Binds directly to 16S ribosomal RNA rpsT - - ko:K02968 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S20p CMS1_k127_2866244_12 1187851.A33M_2516 2.236e-20 92.0 COG0329@1|root,COG0329@2|Bacteria,1MXM5@1224|Proteobacteria,2TUAG@28211|Alphaproteobacteria 28211|Alphaproteobacteria EM Belongs to the DapA family - - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS CMS1_k127_2869030_0 296591.Bpro_2800 8.058e-170 535.0 COG0028@1|root,COG0028@2|Bacteria,1MXDW@1224|Proteobacteria,2VHRD@28216|Betaproteobacteria,4ABWV@80864|Comamonadaceae 28216|Betaproteobacteria EH Belongs to the TPP enzyme family oxc - 4.1.1.8 ko:K01577 ko00630,ko01100,map00630,map01100 - R01908 RC00620 ko00000,ko00001,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N CMS1_k127_2869030_1 375286.mma_2347 6.963e-108 353.0 COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VHB0@28216|Betaproteobacteria,476TX@75682|Oxalobacteraceae 28216|Betaproteobacteria H CoA-transferase family III - - 2.8.3.16,2.8.3.22 ko:K07749,ko:K14471,ko:K14472 ko00660,ko00720,ko01120,ko01200,map00660,map00720,map01120,map01200 M00376 R00406,R03154 RC00014 ko00000,ko00001,ko00002,ko01000 - - - CoA_transf_3 CMS1_k127_2874776_3 1163617.SCD_n02152 1.754e-68 236.0 COG0500@1|root,COG2226@2|Bacteria,1MVXN@1224|Proteobacteria,2VQVG@28216|Betaproteobacteria 28216|Betaproteobacteria Q Methyltransferase type 11 arsM - 2.1.1.137 ko:K07755 - - - - ko00000,ko01000 - - - Methyltransf_31 CMS1_k127_2874776_2 1305735.JAFT01000005_gene1251 5.51e-106 352.0 COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,2TR8F@28211|Alphaproteobacteria 28211|Alphaproteobacteria P COG0491 Zn-dependent hydrolases, including glyoxylases - - - - - - - - - - - - Lactamase_B CMS1_k127_2874776_5 395494.Galf_2173 4.568e-42 156.0 COG1553@1|root,COG1553@2|Bacteria,1NFRH@1224|Proteobacteria 1224|Proteobacteria P Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE - - - ko:K06039 - - - - ko00000 - - - DrsE CMS1_k127_2874776_0 1255043.TVNIR_1705 1.36e-150 485.0 COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,1RQS1@1236|Gammaproteobacteria 1236|Gammaproteobacteria S oxidoreductase - - 1.8.5.4 ko:K17218 ko00920,map00920 - R10152 RC03155 ko00000,ko00001,ko01000 - - - Pyr_redox_2 CMS1_k127_2874776_7 765911.Thivi_1975 0.000308 49.0 2EPYJ@1|root,33HJ5@2|Bacteria,1NGGR@1224|Proteobacteria,1SI73@1236|Gammaproteobacteria,1X1UP@135613|Chromatiales 135613|Chromatiales - - - - - - - - - - - - - - - CMS1_k127_2874776_4 338969.Rfer_0463 1.905e-48 175.0 COG1553@1|root,COG1553@2|Bacteria,1RDFR@1224|Proteobacteria,2VSFK@28216|Betaproteobacteria,4AFYB@80864|Comamonadaceae 28216|Betaproteobacteria P DsrE/DsrF-like family - - - ko:K06039 - - - - ko00000 - - - DrsE CMS1_k127_2874776_1 1049564.TevJSym_ae00660 3.815e-107 363.0 COG0398@1|root,COG0607@1|root,COG0398@2|Bacteria,COG0607@2|Bacteria,1MVF3@1224|Proteobacteria,1RSK1@1236|Gammaproteobacteria 1236|Gammaproteobacteria P SNARE associated Golgi protein ydjX GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - Rhodanese,SNARE_assoc CMS1_k127_2874776_6 1049564.TevJSym_ae00650 3.741e-32 126.0 COG3000@1|root,COG3000@2|Bacteria,1MW5G@1224|Proteobacteria,1RQJQ@1236|Gammaproteobacteria,1J5P9@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria I Fatty acid hydroxylase superfamily - - - - - - - - - - - - FA_hydroxylase CMS1_k127_287857_3 1125973.JNLC01000010_gene1586 6.986e-21 92.0 COG4965@1|root,COG4965@2|Bacteria,1MUXK@1224|Proteobacteria,2TRBI@28211|Alphaproteobacteria,3JR8Y@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria U Type II secretion system (T2SS), protein F MA20_18445 - - ko:K12510 - - - - ko00000,ko02044 - - - T2SSF CMS1_k127_287857_1 1187851.A33M_3696 1.249e-124 409.0 COG2064@1|root,COG2064@2|Bacteria,1MWAZ@1224|Proteobacteria,2TSFA@28211|Alphaproteobacteria,3FD8W@34008|Rhodovulum 28211|Alphaproteobacteria NU Type II secretion system (T2SS), protein F MA20_18450 - - ko:K12511 - - - - ko00000,ko02044 - - - T2SSF CMS1_k127_287857_2 1187851.A33M_3697 1.384e-85 292.0 COG5010@1|root,COG5010@2|Bacteria,1MVTK@1224|Proteobacteria,2TVBA@28211|Alphaproteobacteria 28211|Alphaproteobacteria U COG0457 FOG TPR repeat MA20_18455 - - - - - - - - - - - TPR_10,TPR_12,TPR_16,TPR_19,TPR_2,TPR_4,TPR_8 CMS1_k127_287857_0 1038866.KB902789_gene2652 7.158e-194 612.0 COG1960@1|root,COG1960@2|Bacteria,1MX17@1224|Proteobacteria,2TTRE@28211|Alphaproteobacteria,3JYE6@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Acyl-CoA dehydrogenase, C-terminal domain - - 3.13.1.4 ko:K19966 - - - - ko00000,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N CMS1_k127_287857_4 1429916.X566_06810 3.284e-05 48.0 COG0260@1|root,COG0260@2|Bacteria,1MUIN@1224|Proteobacteria,2TSI6@28211|Alphaproteobacteria,3JTK4@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Belongs to the peptidase M17 family pepA - 3.4.11.1 ko:K01255 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M17 CMS1_k127_2878743_4 331869.BAL199_06619 3.84e-147 471.0 COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TRS8@28211|Alphaproteobacteria 28211|Alphaproteobacteria EP Binding-protein-dependent transport system inner membrane component nikB - - ko:K02033,ko:K15585 ko02010,ko02024,map02010,map02024 M00239,M00440 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 CMS1_k127_2878743_1 1038859.AXAU01000026_gene2330 2.918e-264 826.0 COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,2TT1G@28211|Alphaproteobacteria,3JQQ7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Bacterial extracellular solute-binding proteins, family 5 Middle - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 CMS1_k127_2878743_2 1038859.AXAU01000026_gene2329 4.331e-187 589.0 COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,2TQTV@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Belongs to the ABC transporter superfamily - - - ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY CMS1_k127_2878743_3 1038859.AXAU01000026_gene2328 5.012e-168 532.0 COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,2TR0J@28211|Alphaproteobacteria,3JRF7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria EP Oligopeptide/dipeptide transporter, C-terminal region - - - ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY CMS1_k127_2878743_6 1411123.JQNH01000001_gene1838 8.305e-121 394.0 COG1024@1|root,COG1024@2|Bacteria,1MVQN@1224|Proteobacteria,2TUXD@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Enoyl-CoA hydratase - - 5.3.3.18 ko:K15866 ko00360,ko01120,map00360,map01120 - R09837,R09839 RC00004,RC00326,RC02689,RC03003 ko00000,ko00001,ko01000 - - - ECH_1 CMS1_k127_2878743_5 1125973.JNLC01000010_gene1962 4.326e-143 465.0 COG0446@1|root,COG0446@2|Bacteria,1NR3M@1224|Proteobacteria,2TS0K@28211|Alphaproteobacteria,3JURU@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Reductase C-terminal MA20_16930 - 1.18.1.3 ko:K00529 ko00071,ko00360,ko01120,ko01220,map00071,map00360,map01120,map01220 M00545 R02000,R06782,R06783 RC00098 br01602,ko00000,ko00001,ko00002,ko01000 - - - Pyr_redox_2,Reductase_C CMS1_k127_2878743_7 1297863.APJF01000026_gene3715 5.836e-117 384.0 COG2159@1|root,COG2159@2|Bacteria,1R5PG@1224|Proteobacteria,2U2G9@28211|Alphaproteobacteria,3JWBY@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Amidohydrolase - - - - - - - - - - - - Amidohydro_2 CMS1_k127_2878743_0 1038858.AXBA01000011_gene1446 0.0 1097.0 COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TQMW@28211|Alphaproteobacteria,3EY29@335928|Xanthobacteraceae 28211|Alphaproteobacteria C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - - - - - - - - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 CMS1_k127_2878743_9 1297863.APJF01000026_gene3713 1.743e-72 250.0 COG2080@1|root,COG2080@2|Bacteria,1RKCM@1224|Proteobacteria,2V8HD@28211|Alphaproteobacteria,3K3A7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C [2Fe-2S] binding domain - - - - - - - - - - - - Fer2,Fer2_2 CMS1_k127_2878743_8 1038858.AXBA01000011_gene1444 1.003e-84 290.0 COG1319@1|root,COG1319@2|Bacteria,1MUDB@1224|Proteobacteria,2TTJF@28211|Alphaproteobacteria 28211|Alphaproteobacteria C carbon monoxide dehydrogenase - - - - - - - - - - - - CO_deh_flav_C,FAD_binding_5 CMS1_k127_2878743_10 189753.AXAS01000058_gene146 5.494e-61 212.0 COG0662@1|root,COG0662@2|Bacteria,1N1XN@1224|Proteobacteria,2U6GE@28211|Alphaproteobacteria,3JY7Y@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G Cupin - - - - - - - - - - - - Cupin_2 CMS1_k127_2887900_12 269799.Gmet_0910 1.817e-46 183.0 COG3303@1|root,COG3303@2|Bacteria,1R8WP@1224|Proteobacteria,42VEM@68525|delta/epsilon subdivisions,2WRGV@28221|Deltaproteobacteria 28221|Deltaproteobacteria C Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - - - - - - - - - - - CMS1_k127_2887900_5 1283300.ATXB01000002_gene2887 7.806e-112 370.0 COG3005@1|root,COG3005@2|Bacteria,1R4UP@1224|Proteobacteria,1RZUI@1236|Gammaproteobacteria 1236|Gammaproteobacteria C cytochrome C family protein - - - - - - - - - - - - Cytochrome_C554,Paired_CXXCH_1 CMS1_k127_2887900_3 1283300.ATXB01000002_gene2886 1.768e-156 519.0 COG3637@1|root,COG3637@2|Bacteria,1R42W@1224|Proteobacteria,1RYPE@1236|Gammaproteobacteria 1236|Gammaproteobacteria M Putative outer membrane beta-barrel porin, MtrB/PioB - - - - - - - - - - - - MtrB_PioB CMS1_k127_2887900_16 1349767.GJA_4406 6.885e-26 113.0 2E193@1|root,32WPE@2|Bacteria,1PA4R@1224|Proteobacteria,2VVMZ@28216|Betaproteobacteria,474M6@75682|Oxalobacteraceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_2887900_2 1288494.EBAPG3_25340 2.276e-177 563.0 COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,2VM1X@28216|Betaproteobacteria,374KT@32003|Nitrosomonadales 28216|Betaproteobacteria U Type II secretion system (T2SS), protein F gspF - - ko:K02455 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSF CMS1_k127_2887900_0 1288494.EBAPG3_25330 4.777e-241 755.0 COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria,3727G@32003|Nitrosomonadales 28216|Betaproteobacteria NU Type II/IV secretion system protein gspE - - ko:K02454 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSE,T2SSE_N CMS1_k127_2887900_1 1163408.UU9_12123 1.13e-235 749.0 COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,1RPJS@1236|Gammaproteobacteria,1X4RY@135614|Xanthomonadales 135614|Xanthomonadales NU secretion system protein xcsD - - ko:K02453 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - Secretin,Secretin_N CMS1_k127_2887900_13 1288494.EBAPG3_25310 1.548e-40 155.0 2DTKB@1|root,33KR8@2|Bacteria,1NGWI@1224|Proteobacteria,2VY5N@28216|Betaproteobacteria,374CG@32003|Nitrosomonadales 28216|Betaproteobacteria U Type II secretion system protein C - - - ko:K02452 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSC CMS1_k127_2887900_7 1288494.EBAPG3_25270 6.905e-68 233.0 COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,2VR7N@28216|Betaproteobacteria,3743R@32003|Nitrosomonadales 28216|Betaproteobacteria U Type II secretion system (T2SS), protein G gspG - - ko:K02456 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - N_methyl,T2SSG CMS1_k127_2887900_10 1288494.EBAPG3_25260 1.163e-58 212.0 COG4970@1|root,COG4970@2|Bacteria,1N9H1@1224|Proteobacteria,2WHHG@28216|Betaproteobacteria,3748R@32003|Nitrosomonadales 28216|Betaproteobacteria U Type II transport protein GspH - - - ko:K02457 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - GspH,N_methyl CMS1_k127_2887900_14 1288494.EBAPG3_25250 8.752e-39 151.0 COG2165@1|root,COG2165@2|Bacteria,1N0C2@1224|Proteobacteria,2VVJ8@28216|Betaproteobacteria,374BR@32003|Nitrosomonadales 28216|Betaproteobacteria NU Type II secretion system (T2SS), protein I gspI - - ko:K02458 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - N_methyl,T2SSI CMS1_k127_2887900_6 1288494.EBAPG3_25240 2.895e-69 244.0 COG4795@1|root,COG4795@2|Bacteria,1Q8VQ@1224|Proteobacteria,2WBWY@28216|Betaproteobacteria,373Y8@32003|Nitrosomonadales 28216|Betaproteobacteria U Type II secretion system (T2SS), protein J - - - ko:K02459 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - N_methyl,T2SSJ CMS1_k127_2887900_8 580332.Slit_0492 4.199e-67 243.0 COG3156@1|root,COG3156@2|Bacteria,1RBNV@1224|Proteobacteria,2VS9P@28216|Betaproteobacteria 28216|Betaproteobacteria U general secretion pathway protein K gspK - - ko:K02460 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSK CMS1_k127_2887900_4 1288494.EBAPG3_25220 1.243e-136 448.0 COG3297@1|root,COG3297@2|Bacteria,1PWC1@1224|Proteobacteria,2WBWZ@28216|Betaproteobacteria,373YD@32003|Nitrosomonadales 28216|Betaproteobacteria U GspL periplasmic domain - - - ko:K02461 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - GspL_C,T2SSL CMS1_k127_2887900_15 323848.Nmul_A1892 9.401e-39 151.0 COG3149@1|root,COG3149@2|Bacteria,1NMTJ@1224|Proteobacteria,2WC57@28216|Betaproteobacteria,374BE@32003|Nitrosomonadales 28216|Betaproteobacteria U Type II secretion system (T2SS), protein M - - - ko:K02462 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - T2SSM CMS1_k127_2887900_11 338969.Rfer_2737 1.293e-50 183.0 COG2204@1|root,COG2204@2|Bacteria,1P58Q@1224|Proteobacteria 1224|Proteobacteria T Pfam Response regulator receiver - - - - - - - - - - - - Response_reg CMS1_k127_2887900_17 338969.Rfer_2738 4.617e-06 50.0 COG2204@1|root,COG2204@2|Bacteria,1QZ6X@1224|Proteobacteria 1224|Proteobacteria T response regulator - - - - - - - - - - - - Response_reg CMS1_k127_2898146_2 1197906.CAJQ02000011_gene580 9.909e-29 117.0 COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,2U747@28211|Alphaproteobacteria,3JR9A@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) moaC - 4.6.1.17 ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R11372 RC03425 ko00000,ko00001,ko01000 - - - MoaC CMS1_k127_2898146_0 316055.RPE_2590 1.624e-114 375.0 COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,2TSZE@28211|Alphaproteobacteria,3JQR7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Belongs to the TrpC family trpC GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48,5.3.1.24 ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03508,R03509 RC00944,RC00945 ko00000,ko00001,ko00002,ko01000 - - - IGPS CMS1_k127_2898146_1 316057.RPD_2828 1.593e-60 211.0 COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,2TR8S@28211|Alphaproteobacteria,3JVIJ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) trpD GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R00985,R00986,R01073 RC00010,RC00440,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Glycos_trans_3N,Glycos_transf_3 CMS1_k127_2903907_4 1038860.AXAP01000011_gene257 1.26e-05 52.0 COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TQMW@28211|Alphaproteobacteria,3JS8F@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain MA20_08005 - 1.2.5.3 ko:K03520 - - R11168 RC02800 ko00000,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 CMS1_k127_2903907_0 1187851.A33M_2503 0.0 1556.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria,3FCUQ@34008|Rhodovulum 28211|Alphaproteobacteria U AcrB/AcrD/AcrF family - - - ko:K18138,ko:K18146 ko01501,ko01503,map01501,map01503 M00647,M00649,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000 2.A.6.2,2.A.6.2.40 - - ACR_tran CMS1_k127_2903907_2 1187851.A33M_2504 1.02e-144 470.0 COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,2V90E@28211|Alphaproteobacteria,3FE5W@34008|Rhodovulum 1224|Proteobacteria M Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 CMS1_k127_2903907_1 1187851.A33M_2505 4.075e-205 649.0 COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,2TS44@28211|Alphaproteobacteria,3FCWU@34008|Rhodovulum 28211|Alphaproteobacteria U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane murJ - - ko:K03980 - - - - ko00000,ko01011,ko02000 2.A.66.4 - - MVIN CMS1_k127_2903907_3 1187851.A33M_4197 1.971e-82 279.0 COG0662@1|root,COG0836@1|root,COG0662@2|Bacteria,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,2TT0R@28211|Alphaproteobacteria,3FCHV@34008|Rhodovulum 28211|Alphaproteobacteria GM Mannose-6-phosphate isomerase manC - 2.7.7.13,5.3.1.8 ko:K00971,ko:K16011 ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025 M00114,M00361,M00362 R00885,R01819 RC00002,RC00376 ko00000,ko00001,ko00002,ko01000 - - - MannoseP_isomer,NTP_transferase CMS1_k127_2908372_5 1187851.A33M_3035 8.215e-124 401.0 COG0596@1|root,COG0596@2|Bacteria,1MUVB@1224|Proteobacteria,2TREP@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Alpha beta hydrolase MA20_05720 - 3.8.1.3 ko:K01561 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05287 RC00697 ko00000,ko00001,ko01000 - - - Abhydrolase_1 CMS1_k127_2908372_0 323098.Nwi_2552 4.123e-207 651.0 COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,2TQR5@28211|Alphaproteobacteria,3JSI5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria F Belongs to the GARS family purD - 6.3.4.13 ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144 RC00090,RC00166 ko00000,ko00001,ko00002,ko01000 - - - GARS_A,GARS_C,GARS_N CMS1_k127_2908372_2 1380355.JNIJ01000015_gene5862 1.125e-193 617.0 COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,2TR1R@28211|Alphaproteobacteria,3JR19@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseA - 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 CMS1_k127_2908372_11 1125973.JNLC01000011_gene230 1.752e-27 120.0 COG3908@1|root,COG3908@2|Bacteria,1N7PA@1224|Proteobacteria,2UFTN@28211|Alphaproteobacteria,3K02P@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Uncharacterized protein conserved in bacteria (DUF2093) MA20_05765 - - - - - - - - - - - DUF2093 CMS1_k127_2908372_6 1429916.X566_13315 4.178e-91 326.0 COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,2TTZ4@28211|Alphaproteobacteria,3JS77@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) lpxK - 2.7.1.130 ko:K00912 ko00540,ko01100,map00540,map01100 M00060 R04657 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 - - - LpxK CMS1_k127_2908372_4 189753.AXAS01000030_gene7204 8.431e-149 482.0 COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,2TS37@28211|Alphaproteobacteria,3JTXY@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) kdtA - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 ko:K02527 ko00540,ko01100,map00540,map01100 M00060,M00080 R04658,R05074,R09763 RC00009,RC00077,RC00247 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT30 - Glycos_transf_N CMS1_k127_2908372_8 189753.AXAS01000030_gene7203 7.268e-71 252.0 COG2121@1|root,COG2121@2|Bacteria,1MZID@1224|Proteobacteria,2TSGQ@28211|Alphaproteobacteria,3JT7J@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Domain of unknown function (DUF374) MA20_05800 - - ko:K09778 - - - - ko00000 - - - DUF374 CMS1_k127_2908372_10 323097.Nham_3180 9.853e-33 132.0 COG0483@1|root,COG0483@2|Bacteria,1N7D7@1224|Proteobacteria,2UF6T@28211|Alphaproteobacteria,3K0ED@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G Domain of unknown function (DUF4170) MA20_05805 - - - - - - - - - - - DUF4170 CMS1_k127_2908372_7 1187851.A33M_3444 3.161e-81 279.0 COG0483@1|root,COG0483@2|Bacteria,1MV4W@1224|Proteobacteria,2TV4R@28211|Alphaproteobacteria,3FDB5@34008|Rhodovulum 28211|Alphaproteobacteria G Inositol monophosphatase family suhB2 - 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P CMS1_k127_2908372_1 1038862.KB893906_gene5320 6.716e-195 618.0 COG0312@1|root,COG0312@2|Bacteria,1MUVW@1224|Proteobacteria,2TSAV@28211|Alphaproteobacteria,3JR0G@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Putative modulator of DNA gyrase pmbA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 - ko:K03592 - - - - ko00000,ko01002 - - - PmbA_TldD CMS1_k127_2908372_9 316055.RPE_0876 4.83e-43 165.0 2E431@1|root,32YZE@2|Bacteria,1N7IT@1224|Proteobacteria,2U6AF@28211|Alphaproteobacteria,3JZ90@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_2908372_3 1038858.AXBA01000006_gene815 7.068e-162 513.0 COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,1MU2Y@1224|Proteobacteria,2TQZ6@28211|Alphaproteobacteria,3F0S7@335928|Xanthobacteraceae 28211|Alphaproteobacteria EQ Hydantoinase/oxoprolinase N-terminal region - - 3.5.2.9 ko:K01469 ko00480,map00480 - R00251 RC00553 ko00000,ko00001,ko01000 - - - Hydant_A_N,Hydantoinase_A,Hydantoinase_B CMS1_k127_2915159_1 316058.RPB_0998 1.064e-230 724.0 COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2TSB1@28211|Alphaproteobacteria,3JTWC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria EH Thiamine pyrophosphate enzyme, central domain MA20_00650 - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N CMS1_k127_2915159_7 1279038.KB907353_gene2312 6.572e-27 117.0 2E5W4@1|root,330K6@2|Bacteria,1N893@1224|Proteobacteria,2UGUZ@28211|Alphaproteobacteria,2JU7W@204441|Rhodospirillales 204441|Rhodospirillales S NIPSNAP - - - - - - - - - - - - NIPSNAP CMS1_k127_2915159_2 1122132.AQYH01000019_gene359 5.206e-221 699.0 COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,2TRJ9@28211|Alphaproteobacteria,4B71U@82115|Rhizobiaceae 28211|Alphaproteobacteria S protein conserved in bacteria - - - ko:K21470 - - - - ko00000,ko01002,ko01011 - - - PG_binding_1,YkuD CMS1_k127_2915159_4 1122132.AQYH01000019_gene358 1.642e-131 427.0 COG0834@1|root,COG0834@2|Bacteria,1MV5D@1224|Proteobacteria,2TSRF@28211|Alphaproteobacteria,4B97N@82115|Rhizobiaceae 28211|Alphaproteobacteria ET ABC-type amino acid transport signal transduction systems, periplasmic component domain aapJ GO:0005575,GO:0005623,GO:0042597,GO:0044464 - ko:K09969 ko02010,map02010 M00232 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.18,3.A.1.3.7,3.A.1.3.8 - - SBP_bac_3 CMS1_k127_2915159_0 861299.J421_0319 4.205e-264 827.0 COG3387@1|root,COG3387@2|Bacteria 2|Bacteria G glucan 1,4-alpha-glucosidase activity - - - - - - - - - - - - Glyco_hydro_15 CMS1_k127_2915159_6 1187851.A33M_0097 3.917e-62 216.0 2D1BA@1|root,32TAA@2|Bacteria,1RJQD@1224|Proteobacteria,2U780@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_2915159_3 1187851.A33M_0095 3.314e-164 531.0 COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,1MU9M@1224|Proteobacteria,2TQJN@28211|Alphaproteobacteria,3FCV5@34008|Rhodovulum 28211|Alphaproteobacteria S AAA domain - - - ko:K07028 - - - - ko00000 - - - AAA_33,APH CMS1_k127_2915159_5 1187851.A33M_0094 8.305e-131 429.0 COG0477@1|root,COG2814@2|Bacteria,1MWFH@1224|Proteobacteria,2TR0R@28211|Alphaproteobacteria 28211|Alphaproteobacteria EGP Major facilitator superfamily - - - - - - - - - - - - MFS_1,Sugar_tr CMS1_k127_2917694_0 1411123.JQNH01000001_gene1127 5.702e-136 443.0 COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,2TRC2@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Acetyl propionyl-CoA carboxylase alpha subunit MA20_30205 - 6.4.1.4 ko:K01968 ko00280,ko01100,map00280,map01100 M00036 R04138 RC00367,RC00942 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2 CMS1_k127_2917694_5 666684.AfiDRAFT_3492 4.907e-31 135.0 2FGXG@1|root,348SR@2|Bacteria,1MXYU@1224|Proteobacteria,2TTD5@28211|Alphaproteobacteria,3JTBT@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_2917694_4 1411123.JQNH01000001_gene3509 4.971e-33 133.0 COG4274@1|root,COG4274@2|Bacteria,1RJBN@1224|Proteobacteria,2UIN0@28211|Alphaproteobacteria 28211|Alphaproteobacteria S GYD domain - - - - - - - - - - - - GYD CMS1_k127_2917694_7 196490.AUEZ01000031_gene2817 1.399e-18 92.0 2DS8Z@1|root,33F1X@2|Bacteria,1N095@1224|Proteobacteria,2UCJ3@28211|Alphaproteobacteria,3K03Q@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - MA20_36060 - - - - - - - - - - - - CMS1_k127_2917694_9 395964.KE386496_gene2788 1.509e-06 54.0 2DS3J@1|root,33ECT@2|Bacteria,1PRVP@1224|Proteobacteria,2V43J@28211|Alphaproteobacteria,3NBUQ@45404|Beijerinckiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_2917694_1 1123072.AUDH01000009_gene444 9.82e-99 332.0 COG0604@1|root,COG0604@2|Bacteria,1MXRX@1224|Proteobacteria,2TRSQ@28211|Alphaproteobacteria,2JWFS@204441|Rhodospirillales 204441|Rhodospirillales C Zinc-binding dehydrogenase - - - - - - - - - - - - ADH_N,ADH_zinc_N CMS1_k127_2917694_10 709797.CSIRO_3938 0.0009593 44.0 COG2211@1|root,COG2211@2|Bacteria,1PF5K@1224|Proteobacteria,2TSWN@28211|Alphaproteobacteria,3JW1C@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G Major facilitator Superfamily - - - - - - - - - - - - MFS_1 CMS1_k127_2917694_3 450851.PHZ_c0642 8.094e-46 175.0 arCOG05203@1|root,31A0K@2|Bacteria,1RHZR@1224|Proteobacteria,2U9JR@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_2917694_2 189753.AXAS01000012_gene4337 1.712e-62 229.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind CMS1_k127_2917694_6 883078.HMPREF9695_02889 7.513e-27 113.0 COG0834@1|root,COG0834@2|Bacteria,1N2RR@1224|Proteobacteria,2U0AF@28211|Alphaproteobacteria,3JUWS@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria ET Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 CMS1_k127_2924613_3 394221.Mmar10_0175 1.613e-101 333.0 COG3316@1|root,COG3316@2|Bacteria,1P9SM@1224|Proteobacteria,2TV17@28211|Alphaproteobacteria,43XZD@69657|Hyphomonadaceae 28211|Alphaproteobacteria L COG3316 Transposase and inactivated derivatives - - - ko:K07498 - - - - ko00000 - - - DDE_Tnp_IS240 CMS1_k127_2924613_0 1346791.M529_21515 1.825e-111 375.0 COG1506@1|root,COG1506@2|Bacteria,1QURS@1224|Proteobacteria,2TW50@28211|Alphaproteobacteria,2KEAZ@204457|Sphingomonadales 204457|Sphingomonadales E BAAT / Acyl-CoA thioester hydrolase C terminal - - - - - - - - - - - - DUF1100,Peptidase_S9 CMS1_k127_2924613_5 1088721.NSU_3476 3.061e-65 234.0 COG0179@1|root,COG0179@2|Bacteria,1R7SI@1224|Proteobacteria,2VFC0@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q Fumarylacetoacetate (FAA) hydrolase family - - - - - - - - - - - - FAA_hydrolase CMS1_k127_2924613_1 314271.RB2654_22053 5.52e-111 379.0 COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,2TVQS@28211|Alphaproteobacteria 28211|Alphaproteobacteria P ABC-type Fe3 transport system permease component - - - ko:K02011 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - BPD_transp_1 CMS1_k127_2924613_7 1298867.AUES01000055_gene4816 1.771e-12 79.0 COG1840@1|root,COG1840@2|Bacteria,1MXZ8@1224|Proteobacteria,2V7DS@28211|Alphaproteobacteria,3JXI6@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P Bacterial extracellular solute-binding protein - - - - - - - - - - - - SBP_bac_11,SBP_bac_6 CMS1_k127_2924613_4 314271.RB2654_22058 1.021e-90 311.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQMJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system - - - - - - - - - - - - ABC_tran,TOBE_2 CMS1_k127_2924613_2 1283283.ATXA01000006_gene1844 6.196e-108 361.0 COG3384@1|root,COG3384@2|Bacteria,2GJDG@201174|Actinobacteria 201174|Actinobacteria S PFAM Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B - - - - - - - - - - - - LigB CMS1_k127_2924613_6 2074.JNYD01000037_gene5138 2.97e-43 163.0 COG5517@1|root,COG5517@2|Bacteria,2HPI9@201174|Actinobacteria,4ECAK@85010|Pseudonocardiales 201174|Actinobacteria Q Ring hydroxylating beta subunit - - 1.14.12.25 ko:K16303 ko00622,ko01120,ko01220,map00622,map01120,map01220 M00539 R05247 RC00267 br01602,ko00000,ko00001,ko00002,ko01000 - - - Ring_hydroxyl_B CMS1_k127_2924613_8 1168065.DOK_00190 6.145e-12 67.0 COG4638@1|root,COG4638@2|Bacteria,1N6MJ@1224|Proteobacteria,1RYGT@1236|Gammaproteobacteria,1JANX@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit - - 1.14.12.25 ko:K10619 ko00622,ko01120,ko01220,map00622,map01120,map01220 M00539 R05247 RC00267 br01602,ko00000,ko00001,ko00002,ko01000 - - - Rieske,Ring_hydroxyl_A CMS1_k127_2927804_5 113395.AXAI01000018_gene4835 1.618e-07 57.0 COG1972@1|root,COG1972@2|Bacteria,1MXXX@1224|Proteobacteria,2TU8A@28211|Alphaproteobacteria,3JUMX@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria F Na+ dependent nucleoside transporter C-terminus MA20_32460 - - ko:K03317 - - - - ko00000 2.A.41 - - Gate,Nucleos_tra2_C,Nucleos_tra2_N CMS1_k127_2927804_3 1187851.A33M_2549 2.113e-43 165.0 COG2164@1|root,COG2164@2|Bacteria,1N81P@1224|Proteobacteria,2UF42@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Cyclophilin-like - - - ko:K09143 - - - - ko00000 - - - Cyclophil_like CMS1_k127_2927804_6 316055.RPE_1827 0.0003912 43.0 COG0587@1|root,COG0587@2|Bacteria,1MUE4@1224|Proteobacteria,2TRUB@28211|Alphaproteobacteria,3JUU5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase dnaE2 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 ko:K02337,ko:K14162 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon CMS1_k127_2927804_0 1205680.CAKO01000037_gene1295 5.982e-109 359.0 COG4221@1|root,COG4221@2|Bacteria,1MWXS@1224|Proteobacteria,2TQYY@28211|Alphaproteobacteria,2JRNC@204441|Rhodospirillales 204441|Rhodospirillales S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short CMS1_k127_2927804_4 1120973.AQXL01000126_gene2964 6.667e-41 155.0 COG0853@1|root,COG0853@2|Bacteria,1V70F@1239|Firmicutes,4HIWU@91061|Bacilli,279U2@186823|Alicyclobacillaceae 91061|Bacilli H Aspartate decarboxylase - - 4.1.1.11 ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R00489 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Asp_decarbox CMS1_k127_2927804_2 1443111.JASG01000004_gene3323 4.906e-76 268.0 COG0189@1|root,COG0189@2|Bacteria,1R31M@1224|Proteobacteria,2TVP6@28211|Alphaproteobacteria 28211|Alphaproteobacteria HJ Sugar-transfer associated ATP-grasp - - - - - - - - - - - - ATPgrasp_ST CMS1_k127_2927804_1 113395.AXAI01000011_gene6519 3.432e-105 360.0 COG0520@1|root,COG0520@2|Bacteria,1QEVJ@1224|Proteobacteria,2TX67@28211|Alphaproteobacteria,3JTSQ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - - - - - - - - - - - CMS1_k127_2947149_0 768671.ThimaDRAFT_1023 1.881e-189 602.0 COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,1RN88@1236|Gammaproteobacteria,1WW6B@135613|Chromatiales 135613|Chromatiales M Belongs to the MurCDEF family murC - 6.3.2.8 ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M CMS1_k127_2947149_2 1123399.AQVE01000003_gene2188 5.707e-109 363.0 COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,1RMQ3@1236|Gammaproteobacteria,45ZMS@72273|Thiotrichales 72273|Thiotrichales M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) murG - 2.4.1.227 ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 - R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011 - GT28 - Glyco_tran_28_C,Glyco_transf_28 CMS1_k127_2947149_1 713586.KB900536_gene1374 5.67e-111 369.0 COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,1RMIV@1236|Gammaproteobacteria,1WWCK@135613|Chromatiales 135613|Chromatiales M Peptidoglycan polymerase that is essential for cell division ftsW - - ko:K03588 ko04112,map04112 - - - ko00000,ko00001,ko02000,ko03036 2.A.103.1 - - FTSW_RODA_SPOVE CMS1_k127_2947828_3 398525.KB900701_gene5967 1.809e-27 114.0 COG0596@1|root,COG0596@2|Bacteria,1QTTN@1224|Proteobacteria,2TRYE@28211|Alphaproteobacteria,3JRD7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Serine aminopeptidase, S33 MA20_09375 - 3.1.1.24 ko:K01055 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00568 R02991 RC00825 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_1 CMS1_k127_2947828_2 1038859.AXAU01000016_gene6848 2.852e-75 256.0 COG3427@1|root,COG3427@2|Bacteria,1RHUC@1224|Proteobacteria,2U9HD@28211|Alphaproteobacteria,3JTDF@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Carbon monoxide dehydrogenase subunit G (CoxG) QU41_36325 - - ko:K09386 - - - - ko00000 - - - COXG CMS1_k127_2947828_1 1211115.ALIQ01000118_gene4575 8.006e-80 268.0 COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,2U5BM@28211|Alphaproteobacteria,3NCGW@45404|Beijerinckiaceae 28211|Alphaproteobacteria C [2Fe-2S] binding domain MA20_09390 - 1.2.5.3 ko:K03518 - - R11168 RC02800 ko00000,ko01000 - - - Fer2,Fer2_2 CMS1_k127_2947828_0 1211115.ALIQ01000118_gene4576 7.685e-158 507.0 COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TQMW@28211|Alphaproteobacteria,3NBXQ@45404|Beijerinckiaceae 28211|Alphaproteobacteria C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain coxL - 1.2.5.3 ko:K03520 - - R11168 RC02800 ko00000,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 CMS1_k127_2953677_0 1038859.AXAU01000002_gene424 2.374e-122 404.0 COG0477@1|root,COG2814@2|Bacteria,1MVHG@1224|Proteobacteria,2TRA4@28211|Alphaproteobacteria,3JSPN@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria EGP Major Facilitator Superfamily MA20_42180 - - - - - - - - - - - MFS_1 CMS1_k127_2953677_1 709797.CSIRO_1777 7.279e-83 287.0 COG3773@1|root,COG3773@2|Bacteria,1MWX3@1224|Proteobacteria,2TT15@28211|Alphaproteobacteria,3JT5Q@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Cell Wall Hydrolase sleB - - - - - - - - - - - Hydrolase_2 CMS1_k127_2983756_1 883080.HMPREF9697_02354 8.57e-72 245.0 COG5352@1|root,COG5352@2|Bacteria,1RHI6@1224|Proteobacteria,2TS7F@28211|Alphaproteobacteria,3JSUB@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S GcrA cell cycle regulator gcrA - - ko:K13583 ko04112,map04112 - - - ko00000,ko00001 - - - GcrA CMS1_k127_2983756_0 1040989.AWZU01000022_gene4791 1.553e-136 438.0 COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,2TSGT@28211|Alphaproteobacteria,3JRG7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Aminotransferase class-III argD GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.17 ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 CMS1_k127_2988034_12 420324.KI912063_gene6832 9.005e-64 227.0 COG3219@1|root,COG3219@2|Bacteria,1PSSN@1224|Proteobacteria,2UVBT@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Putative DNA-binding domain - - - - - - - - - - - - DUF2063 CMS1_k127_2988034_11 420324.KI912063_gene6831 5.514e-64 222.0 COG2259@1|root,COG2259@2|Bacteria,1N1VA@1224|Proteobacteria,2UBY7@28211|Alphaproteobacteria 28211|Alphaproteobacteria S DoxX - - - ko:K15977 - - - - ko00000 - - - DoxX CMS1_k127_2988034_6 1429916.X566_04865 6.084e-144 470.0 COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,2TR47@28211|Alphaproteobacteria,3JTX8@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G Glucose / Sorbosone dehydrogenase yliI GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016901,GO:0019842,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046872,GO:0048037,GO:0048038,GO:0055114,GO:0070968,GO:0097159,GO:1901363 1.1.5.2 ko:K00117,ko:K21430 ko00030,ko01100,ko01110,ko01130,map00030,map01100,map01110,map01130 - R06620 RC00066 ko00000,ko00001,ko01000 - - - GSDH CMS1_k127_2988034_8 1429916.X566_04855 2.947e-101 334.0 COG0625@1|root,COG0625@2|Bacteria,1REDI@1224|Proteobacteria,2TR9W@28211|Alphaproteobacteria,3JRNA@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O Belongs to the GST superfamily MA20_05235 - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_N,GST_N_3 CMS1_k127_2988034_5 1197906.CAJQ02000047_gene4099 1.4e-147 474.0 COG1215@1|root,COG1215@2|Bacteria,1QU2F@1224|Proteobacteria,2U0P8@28211|Alphaproteobacteria,3JUHE@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 CMS1_k127_2988034_4 1429916.X566_04850 4.308e-152 494.0 2CIPC@1|root,2Z9HB@2|Bacteria,1R3W8@1224|Proteobacteria,2TST7@28211|Alphaproteobacteria,3JTHB@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Glycosyltransferase family 87 - - - - - - - - - - - - GT87 CMS1_k127_2988034_1 1245469.S58_61440 1.198e-214 671.0 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2TRPK@28211|Alphaproteobacteria,3JTIB@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E DegT/DnrJ/EryC1/StrS aminotransferase family aatA - 2.6.1.1 ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R02433,R02619,R05052 RC00006 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 CMS1_k127_2988034_10 1211115.ALIQ01000018_gene2168 4.838e-67 240.0 COG0715@1|root,COG0715@2|Bacteria,1NF3S@1224|Proteobacteria,2TREQ@28211|Alphaproteobacteria,3NCGM@45404|Beijerinckiaceae 28211|Alphaproteobacteria P NMT1-like family MA20_40210 - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 CMS1_k127_2988034_0 1187851.A33M_1937 0.0 1066.0 COG0480@1|root,COG0480@2|Bacteria,1MU2W@1224|Proteobacteria,2TYVK@28211|Alphaproteobacteria,3FE06@34008|Rhodovulum 28211|Alphaproteobacteria J Elongation factor G, domain IV MA20_05220 - - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 CMS1_k127_2988034_7 1380394.JADL01000001_gene2656 4.716e-141 454.0 COG2041@1|root,COG2041@2|Bacteria,1MUW0@1224|Proteobacteria,2TS40@28211|Alphaproteobacteria,2JQW1@204441|Rhodospirillales 204441|Rhodospirillales S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide msrP - - ko:K07147 - - - - ko00000,ko01000 - - - Oxidored_molyb CMS1_k127_2988034_2 1120792.JAFV01000001_gene779 1.775e-174 556.0 COG0624@1|root,COG0624@2|Bacteria,1MVUX@1224|Proteobacteria,2TR5X@28211|Alphaproteobacteria,36ZW3@31993|Methylocystaceae 28211|Alphaproteobacteria E Peptidase family M20/M25/M40 - - 3.5.1.6,3.5.1.87 ko:K06016 ko00240,ko01100,map00240,map01100 M00046 R00905,R04666 RC00096 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 CMS1_k127_2988034_3 196490.AUEZ01000017_gene3196 3.74e-165 533.0 COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TR4Q@28211|Alphaproteobacteria,3JVY3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter TctA family MA20_23145 - - ko:K07793 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctA CMS1_k127_2988034_13 742741.HMPREF9475_02068 8.845e-06 55.0 2EFUW@1|root,339M2@2|Bacteria,1VFXY@1239|Firmicutes,24NMR@186801|Clostridia,221EB@1506553|Lachnoclostridium 186801|Clostridia S Tripartite tricarboxylate transporter TctB family - - - - - - - - - - - - TctB CMS1_k127_2988034_9 1205680.CAKO01000038_gene1586 3.521e-68 239.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2TQWK@28211|Alphaproteobacteria,2JRXA@204441|Rhodospirillales 204441|Rhodospirillales S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC CMS1_k127_299510_1 1429916.X566_05120 1.42e-51 184.0 COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,2TRKI@28211|Alphaproteobacteria,3JRD0@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE clpB - - ko:K03695 ko04213,map04213 - - - ko00000,ko00001,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N CMS1_k127_299510_0 316058.RPB_4245 9.191e-247 779.0 COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2TT3Z@28211|Alphaproteobacteria,3JTRT@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Peptidase family M23 MA20_20375 - - - - - - - - - - - Peptidase_M23 CMS1_k127_299510_4 1408427.JADB01000006_gene134 2.413e-13 72.0 2DTS4@1|root,33MFD@2|Bacteria,1PTGB@1224|Proteobacteria,2V5BU@28211|Alphaproteobacteria,48UEV@772|Bartonellaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_299510_3 498761.HM1_3148 1.275e-20 92.0 2DN97@1|root,32W7A@2|Bacteria,1VANB@1239|Firmicutes,24Q9J@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - CMS1_k127_299976_0 1244869.H261_19913 5.614e-91 302.0 COG0437@1|root,COG0437@2|Bacteria,1R6XQ@1224|Proteobacteria 1224|Proteobacteria C Pyrogallol hydroxytransferase - - - - - - - - - - - - CarboxypepD_reg,Fer4_11 CMS1_k127_299976_1 1244869.H261_19918 3.345e-80 272.0 COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,2TSAP@28211|Alphaproteobacteria,2JRAB@204441|Rhodospirillales 204441|Rhodospirillales C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - - - - - - - - - - Molybdopterin,Molydop_binding CMS1_k127_3015396_4 1205680.CAKO01000004_gene3631 8.261e-56 197.0 COG4231@1|root,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,2TSHH@28211|Alphaproteobacteria,2JSZE@204441|Rhodospirillales 204441|Rhodospirillales C Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates - - - - - - - - - - - - TPP_enzyme_C CMS1_k127_3015396_2 1205680.CAKO01000004_gene3632 1.818e-142 468.0 COG1014@1|root,COG1014@2|Bacteria,1MV7Q@1224|Proteobacteria,2TTHE@28211|Alphaproteobacteria,2JQ2E@204441|Rhodospirillales 204441|Rhodospirillales C Pyruvate ferredoxin/flavodoxin oxidoreductase - - - - - - - - - - - - POR CMS1_k127_3015396_1 1442599.JAAN01000005_gene1025 4.696e-173 562.0 COG0028@1|root,COG0028@2|Bacteria,1MX3Q@1224|Proteobacteria,1RZ17@1236|Gammaproteobacteria 1236|Gammaproteobacteria EH COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N CMS1_k127_3015396_3 670292.JH26_01350 1.532e-137 445.0 COG2159@1|root,COG2159@2|Bacteria,1MXI7@1224|Proteobacteria,2U256@28211|Alphaproteobacteria,1JYIK@119045|Methylobacteriaceae 28211|Alphaproteobacteria S Amidohydrolase - - 4.2.1.83 ko:K10220 ko00362,ko01120,map00362,map01120 - R04478 RC00498 ko00000,ko00001,ko01000 - - - Amidohydro_2 CMS1_k127_3015396_0 1187851.A33M_2772 0.0 1180.0 COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,2TQRR@28211|Alphaproteobacteria,3FCFR@34008|Rhodovulum 28211|Alphaproteobacteria L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V CMS1_k127_3020516_5 1380394.JADL01000007_gene4469 7.202e-52 186.0 COG1788@1|root,COG1788@2|Bacteria,1NGS5@1224|Proteobacteria,2TVMU@28211|Alphaproteobacteria,2JU2U@204441|Rhodospirillales 204441|Rhodospirillales I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit - - 2.8.3.12 ko:K01039 ko00643,ko00650,ko01120,map00643,map00650,map01120 - R04000,R05509 RC00012,RC00131,RC00137 ko00000,ko00001,ko01000 - - - CoA_trans CMS1_k127_3020516_2 1380394.JADL01000020_gene1825 3.329e-114 376.0 COG0685@1|root,COG0685@2|Bacteria,1MXTZ@1224|Proteobacteria,2TWKE@28211|Alphaproteobacteria,2JRIW@204441|Rhodospirillales 28211|Alphaproteobacteria E Methylenetetrahydrofolate reductase - - - - - - - - - - - - MTHFR CMS1_k127_3020516_3 1430440.MGMSRv2_2139 3.613e-79 276.0 COG0523@1|root,COG0523@2|Bacteria,1MVZV@1224|Proteobacteria,2TS4B@28211|Alphaproteobacteria,2JQ6A@204441|Rhodospirillales 204441|Rhodospirillales S cobalamin synthesis protein - - - - - - - - - - - - CobW_C,cobW CMS1_k127_3020516_0 1120983.KB894577_gene3582 9.072e-173 550.0 COG5276@1|root,COG5276@2|Bacteria,1MU72@1224|Proteobacteria,2TZVG@28211|Alphaproteobacteria,1JQCV@119043|Rhodobiaceae 28211|Alphaproteobacteria S LVIVD repeat - - - - - - - - - - - - LVIVD CMS1_k127_3020516_9 658612.MD26_13340 1.682e-14 86.0 COG4521@1|root,COG4521@2|Bacteria,1R07T@1224|Proteobacteria 1224|Proteobacteria P Substrate binding domain of ABC-type glycine betaine transport system - - - - - - - - - - - - NMT1 CMS1_k127_3020516_4 579137.Metvu_0823 2.627e-77 271.0 COG1116@1|root,arCOG00193@2157|Archaea,2XT97@28890|Euryarchaeota,23QHW@183939|Methanococci 183939|Methanococci P PFAM ABC transporter related - - - ko:K02049 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - ABC_tran CMS1_k127_3020516_8 257310.BB3564 5.756e-41 162.0 COG0600@1|root,COG0600@2|Bacteria,1MU6Q@1224|Proteobacteria,2VH12@28216|Betaproteobacteria,3T6EC@506|Alcaligenaceae 28216|Betaproteobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K02050,ko:K15552 ko00920,ko02010,map00920,map02010 M00188,M00435 - - ko00000,ko00001,ko00002,ko02000 3.A.1.16,3.A.1.17,3.A.1.17.1,3.A.1.17.4 - - BPD_transp_1 CMS1_k127_3020516_7 257313.BP0915 1.27e-45 177.0 COG0600@1|root,COG0600@2|Bacteria,1MU6Q@1224|Proteobacteria,2VH12@28216|Betaproteobacteria,3T6EC@506|Alcaligenaceae 28216|Betaproteobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K02050,ko:K15552 ko00920,ko02010,map00920,map02010 M00188,M00435 - - ko00000,ko00001,ko00002,ko02000 3.A.1.16,3.A.1.17,3.A.1.17.1,3.A.1.17.4 - - BPD_transp_1 CMS1_k127_3020516_1 991905.SL003B_1045 6.719e-131 425.0 COG2084@1|root,COG2084@2|Bacteria,1P0X0@1224|Proteobacteria,2U255@28211|Alphaproteobacteria,4BSC8@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - 1.1.1.31 ko:K00020 ko00280,ko01100,map00280,map01100 - R05066 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 CMS1_k127_3020516_6 1280947.HY30_13390 1.107e-46 172.0 296ZZ@1|root,2ZU8H@2|Bacteria,1RED2@1224|Proteobacteria,2U6CK@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_3044332_14 1417296.U879_08105 5.943e-12 71.0 COG0509@1|root,COG0509@2|Bacteria,1RKRS@1224|Proteobacteria,2UAPN@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Glycine cleavage H-protein - - - ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 - - - GCV_H CMS1_k127_3044332_13 1417296.U879_08100 3.507e-50 187.0 2AKRU@1|root,31BIQ@2|Bacteria,1Q7DM@1224|Proteobacteria,2UEKS@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_3044332_3 1417296.U879_08095 1.59e-175 561.0 COG2048@1|root,COG2048@2|Bacteria,1N37J@1224|Proteobacteria,2U4AQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Cysteine-rich domain - - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 ko:K03389 ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200 M00356,M00357,M00563,M00567 R04540,R11928,R11931,R11943,R11944 RC00011 ko00000,ko00001,ko00002,ko01000 - - - CCG CMS1_k127_3044332_7 1417296.U879_08090 1.158e-129 417.0 COG1150@1|root,COG1150@2|Bacteria,1R874@1224|Proteobacteria,2U3QM@28211|Alphaproteobacteria 28211|Alphaproteobacteria C 4Fe-4S dicluster domain - - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 ko:K03390 ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200 M00356,M00357,M00563,M00567 R04540,R11928,R11931,R11943,R11944 RC00011 ko00000,ko00001,ko00002,ko01000 - - - Fer4_9 CMS1_k127_3044332_8 1417296.U879_08085 1.26e-115 380.0 arCOG05916@1|root,30GTU@2|Bacteria,1RDX8@1224|Proteobacteria,2U853@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_3044332_4 1417296.U879_08080 8.669e-174 550.0 COG0446@1|root,COG1148@1|root,COG0446@2|Bacteria,COG1148@2|Bacteria,1R882@1224|Proteobacteria,2U526@28211|Alphaproteobacteria 28211|Alphaproteobacteria C FAD dependent oxidoreductase - - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 ko:K03388 ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200 M00356,M00357,M00563,M00567 R04540,R11928,R11931,R11943,R11944 RC00011 ko00000,ko00001,ko00002,ko01000 - - - FAD_oxidored,Pyr_redox_2 CMS1_k127_3044332_1 1417296.U879_08075 5.778e-263 814.0 COG2048@1|root,COG2048@2|Bacteria,1R97P@1224|Proteobacteria,2TSIB@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Cysteine-rich domain - - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 ko:K03389 ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200 M00356,M00357,M00563,M00567 R04540,R11928,R11931,R11943,R11944 RC00011 ko00000,ko00001,ko00002,ko01000 - - - CCG CMS1_k127_3044332_5 1417296.U879_08070 2.956e-140 448.0 COG1150@1|root,COG1150@2|Bacteria,1R7PH@1224|Proteobacteria,2U2FE@28211|Alphaproteobacteria 28211|Alphaproteobacteria C 4Fe-4S dicluster domain - - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 ko:K03390 ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200 M00356,M00357,M00563,M00567 R04540,R11928,R11931,R11943,R11944 RC00011 ko00000,ko00001,ko00002,ko01000 - - - Fer4_8 CMS1_k127_3044332_12 371731.Rsw2DRAFT_3295 2.383e-71 242.0 COG2044@1|root,COG2044@2|Bacteria,1RGWS@1224|Proteobacteria,2UB97@28211|Alphaproteobacteria 28211|Alphaproteobacteria S DsrE/DsrF/DrsH-like family - - - - - - - - - - - - DrsE_2 CMS1_k127_3044332_11 1417296.U879_08060 5.015e-79 270.0 COG0518@1|root,COG0518@2|Bacteria,1MYXC@1224|Proteobacteria,2UBE9@28211|Alphaproteobacteria 28211|Alphaproteobacteria F GMP synthase (glutamine-hydrolyzing) activity - - - - - - - - - - - - - CMS1_k127_3044332_6 582899.Hden_0683 3.537e-137 444.0 COG1856@1|root,COG1856@2|Bacteria,1R6PW@1224|Proteobacteria,2U1YU@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Radical SAM - - - ko:K09711 - - - - ko00000 - - - Radical_SAM CMS1_k127_3044332_10 1417296.U879_08045 1.737e-92 316.0 COG0644@1|root,COG0644@2|Bacteria,1MXQY@1224|Proteobacteria,2TVK0@28211|Alphaproteobacteria 28211|Alphaproteobacteria C geranylgeranyl reductase - - - - - - - - - - - - FAD_binding_3,FAD_oxidored,Lycopene_cycl,Trp_halogenase CMS1_k127_3044332_2 371731.Rsw2DRAFT_1853 4.821e-192 608.0 COG2516@1|root,COG2516@2|Bacteria,1MWZQ@1224|Proteobacteria,2U4HP@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Radical SAM - - 2.8.1.6 ko:K01012 ko00780,ko01100,map00780,map01100 M00123,M00573,M00577 R01078 RC00441 ko00000,ko00001,ko00002,ko01000 - - - Radical_SAM CMS1_k127_3044332_9 1417296.U879_08035 1.09e-110 368.0 COG0095@1|root,COG0095@2|Bacteria,1N1T8@1224|Proteobacteria,2U1PC@28211|Alphaproteobacteria 28211|Alphaproteobacteria H biotin lipoate A B protein ligase - - 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 - R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB CMS1_k127_3044332_0 1131814.JAFO01000001_gene4492 0.0 1549.0 COG0604@1|root,COG1020@1|root,COG1028@1|root,COG3321@1|root,COG0604@2|Bacteria,COG1020@2|Bacteria,COG1028@2|Bacteria,COG3321@2|Bacteria,1QK4F@1224|Proteobacteria,2TRUN@28211|Alphaproteobacteria,3F2CR@335928|Xanthobacteraceae 28211|Alphaproteobacteria Q Acyl transferase domain in polyketide synthase (PKS) enzymes. - - - - - - - - - - - - ADH_N,ADH_zinc_N,AMP-binding,AMP-binding_C,Acyl_transf_1,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,NAD_binding_4,PP-binding,PS-DH,Thioesterase,ketoacyl-synt CMS1_k127_3045296_3 1298867.AUES01000010_gene5709 9.573e-67 237.0 COG4233@1|root,COG4233@2|Bacteria,1REVE@1224|Proteobacteria,2VEXK@28211|Alphaproteobacteria,3JTR6@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria CO Disulphide bond corrector protein DsbC - - - - - - - - - - - - DsbC CMS1_k127_3045296_2 1187851.A33M_1497 2.14e-101 335.0 COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,2TTX4@28211|Alphaproteobacteria,3FD46@34008|Rhodovulum 28211|Alphaproteobacteria K Uncharacterized ACR, COG1678 MA20_18155 - - ko:K07735 - - - - ko00000,ko03000 - - - DUF179 CMS1_k127_3045296_0 1298867.AUES01000010_gene5696 0.0 1499.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria,3JT9B@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Diguanylate cyclase MA20_18100 - 3.1.4.52 ko:K13245 ko04112,map04112 - R08991 RC00296 ko00000,ko00001,ko01000 - - - 7TMR-DISMED2,7TMR-DISM_7TM,EAL,GGDEF,PAS_3 CMS1_k127_3045296_1 1187851.A33M_1495 3.51e-113 369.0 COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,2TR1J@28211|Alphaproteobacteria,3FCNK@34008|Rhodovulum 28211|Alphaproteobacteria C Zinc-binding dehydrogenase MA20_18095 - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N CMS1_k127_3058616_3 323098.Nwi_1073 3.18e-25 109.0 COG0392@1|root,COG0392@2|Bacteria,1MVZ8@1224|Proteobacteria,2TTDM@28211|Alphaproteobacteria,3JS9U@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Lysylphosphatidylglycerol synthase TM region - - - ko:K07027 - - - - ko00000,ko02000 4.D.2 - - LPG_synthase_TM CMS1_k127_3058616_1 1429916.X566_01765 2.022e-114 375.0 COG0176@1|root,COG0176@2|Bacteria,1QAUK@1224|Proteobacteria 1224|Proteobacteria H Transaldolase tal - 2.2.1.2 ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01827 RC00439,RC00604 ko00000,ko00001,ko00002,ko01000 - - - TAL_FSA CMS1_k127_3058616_0 1297865.APJD01000047_gene4796 7.024e-155 495.0 COG0673@1|root,COG0673@2|Bacteria,1MV7C@1224|Proteobacteria,2TQM1@28211|Alphaproteobacteria,3JSWB@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Oxidoreductase family, NAD-binding Rossmann fold MA20_07975 - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C CMS1_k127_3058616_2 1038859.AXAU01000009_gene1445 3.811e-38 145.0 COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2TRIQ@28211|Alphaproteobacteria,3JSYW@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Belongs to the DegT DnrJ EryC1 family MA20_07980 - - - - - - - - - - - DegT_DnrJ_EryC1 CMS1_k127_30649_6 1123392.AQWL01000005_gene3007 4.057e-49 180.0 COG0589@1|root,COG0589@2|Bacteria,1N02E@1224|Proteobacteria,2VU60@28216|Betaproteobacteria,1KTAA@119069|Hydrogenophilales 119069|Hydrogenophilales T Universal stress protein family - - - - - - - - - - - - Usp CMS1_k127_30649_7 1123392.AQWL01000003_gene139 3.682e-40 153.0 COG2370@1|root,COG2370@2|Bacteria,1N08F@1224|Proteobacteria,2VTYR@28216|Betaproteobacteria,1KT35@119069|Hydrogenophilales 119069|Hydrogenophilales O HupE / UreJ protein - - - - - - - - - - - - HupE_UreJ CMS1_k127_30649_4 1123392.AQWL01000005_gene3007 5.086e-55 198.0 COG0589@1|root,COG0589@2|Bacteria,1N02E@1224|Proteobacteria,2VU60@28216|Betaproteobacteria,1KTAA@119069|Hydrogenophilales 119069|Hydrogenophilales T Universal stress protein family - - - - - - - - - - - - Usp CMS1_k127_30649_9 500635.MITSMUL_04252 1.131e-07 57.0 COG0298@1|root,COG0298@2|Bacteria,1VFE0@1239|Firmicutes,4H5P1@909932|Negativicutes 909932|Negativicutes O Hydrogenase assembly chaperone hypC hupF hypC - - ko:K04653 - - - - ko00000 - - - HupF_HypC CMS1_k127_30649_5 292415.Tbd_1382 1.461e-49 181.0 COG0375@1|root,COG0375@2|Bacteria,1MZJH@1224|Proteobacteria,2VYD4@28216|Betaproteobacteria 28216|Betaproteobacteria S Hydrogenase/urease nickel incorporation, metallochaperone, hypA - - - ko:K04651 - - - - ko00000,ko03110 - - - HypA CMS1_k127_30649_1 1123393.KB891326_gene128 4.434e-160 505.0 COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,2VJKH@28216|Betaproteobacteria,1KSKW@119069|Hydrogenophilales 119069|Hydrogenophilales KO CobW/HypB/UreG, nucleotide-binding domain - - - - - - - - - - - - cobW CMS1_k127_30649_3 118166.JH976537_gene2365 5.07e-76 257.0 COG3837@1|root,COG3837@2|Bacteria,1G62V@1117|Cyanobacteria,1HBPF@1150|Oscillatoriales 1117|Cyanobacteria S Cupin domain - - - - - - - - - - - - Cupin_2 CMS1_k127_30649_2 1163617.SCD_n02576 8.191e-100 329.0 COG2808@1|root,COG2808@2|Bacteria,1N1B9@1224|Proteobacteria,2VRAJ@28216|Betaproteobacteria 28216|Betaproteobacteria K Transcriptional regulator paiB - - ko:K07734 - - - - ko00000,ko03000 - - - FMN_bind_2 CMS1_k127_30649_0 1123392.AQWL01000003_gene149 3.837e-209 651.0 COG0409@1|root,COG0409@2|Bacteria,1MU1F@1224|Proteobacteria,2VHKM@28216|Betaproteobacteria,1KSAW@119069|Hydrogenophilales 119069|Hydrogenophilales O Hydrogenase formation hypA family - - - - - - - - - - - - HypD CMS1_k127_3073334_7 65071.PYU1_T002219 6.245e-46 175.0 COG1028@1|root,KOG0725@2759|Eukaryota,1MA7U@121069|Pythiales 121069|Pythiales Q Carbohydrate esterase. Source PGD - - - - - - - - - - - - adh_short_C2 CMS1_k127_3073334_12 1298867.AUES01000040_gene986 1.208e-05 48.0 COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,2TQKG@28211|Alphaproteobacteria,3JRCP@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate leuB GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh CMS1_k127_3073334_6 1157708.KB907452_gene4005 1.053e-64 223.0 COG2128@1|root,COG2128@2|Bacteria,1RD2I@1224|Proteobacteria,2VV72@28216|Betaproteobacteria 28216|Betaproteobacteria O Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - - - - - - - - - - CMD CMS1_k127_3073334_3 443598.AUFA01000034_gene7246 8.542e-97 333.0 COG0697@1|root,COG0697@2|Bacteria,1MXCD@1224|Proteobacteria,2TR27@28211|Alphaproteobacteria,3JRUH@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria EG EamA-like transporter family MA20_35690 - - - - - - - - - - - EamA CMS1_k127_3073334_8 1446473.JHWH01000007_gene571 5.01e-42 160.0 COG2050@1|root,COG2050@2|Bacteria,1PP3J@1224|Proteobacteria,2U5E4@28211|Alphaproteobacteria,2PX26@265|Paracoccus 28211|Alphaproteobacteria Q Domain of unknown function (DUF4442) MA20_28520 - - - - - - - - - - - 4HBT CMS1_k127_3073334_2 864069.MicloDRAFT_00055390 1.506e-121 399.0 COG0450@1|root,COG0450@2|Bacteria,1MX2B@1224|Proteobacteria,2TT09@28211|Alphaproteobacteria,1JUHK@119045|Methylobacteriaceae 28211|Alphaproteobacteria O C-terminal domain of 1-Cys peroxiredoxin MA20_35715 - 1.11.1.15 ko:K03386 ko04214,map04214 - - - ko00000,ko00001,ko01000,ko04147 - - - 1-cysPrx_C,AhpC-TSA CMS1_k127_3073334_1 1157490.EL26_22565 2.442e-159 529.0 COG3211@1|root,COG3211@2|Bacteria,1UYPE@1239|Firmicutes,4HCRC@91061|Bacilli,278TS@186823|Alicyclobacillaceae 91061|Bacilli S Bacterial protein of unknown function (DUF839) - - - ko:K07093 - - - - ko00000 - - - Cu_amine_oxidN1,DUF839 CMS1_k127_3073334_4 1038858.AXBA01000036_gene34 2.392e-83 293.0 COG3174@1|root,COG3174@2|Bacteria,1NDBI@1224|Proteobacteria,2U0C9@28211|Alphaproteobacteria,3EZBG@335928|Xanthobacteraceae 28211|Alphaproteobacteria S Domain of unknown function (DUF4010) - - - - - - - - - - - - DUF4010,MgtC CMS1_k127_3073334_0 1230476.C207_06006 0.0 1032.0 COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,2TRC2@28211|Alphaproteobacteria,3JSG7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Biotin carboxylase C-terminal domain pccA GO:0003674,GO:0003824,GO:0004658,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009374,GO:0009987,GO:0016421,GO:0016874,GO:0016885,GO:0017144,GO:0019752,GO:0019842,GO:0019899,GO:0031406,GO:0031974,GO:0032787,GO:0033218,GO:0033293,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0070013,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901681 6.4.1.3 ko:K01965 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 M00373,M00741 R01859 RC00097,RC00609 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2 CMS1_k127_3073334_5 1121861.KB899917_gene3594 2.749e-73 254.0 COG1878@1|root,COG1878@2|Bacteria,1MV8S@1224|Proteobacteria,2U0U0@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Putative cyclase - - - - - - - - - - - - Cyclase CMS1_k127_3073334_9 1187851.A33M_1737 3.198e-31 130.0 COG3703@1|root,COG3703@2|Bacteria,1RIGV@1224|Proteobacteria,2UA8X@28211|Alphaproteobacteria 28211|Alphaproteobacteria P PFAM AIG2 family protein - - - - - - - - - - - - AIG2_2,GGACT CMS1_k127_3073334_10 1038860.AXAP01000014_gene937 5.412e-29 122.0 COG1254@1|root,COG1254@2|Bacteria,1PU46@1224|Proteobacteria,2UF7Z@28211|Alphaproteobacteria,3K02B@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Belongs to the acylphosphatase family acyP GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 - R00317,R01421,R01515 RC00043 ko00000,ko00001,ko01000 - - - Acylphosphatase CMS1_k127_3073334_11 441620.Mpop_4726 1.359e-25 108.0 COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,2TRXJ@28211|Alphaproteobacteria,1JTNC@119045|Methylobacteriaceae 28211|Alphaproteobacteria H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate lipB GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 ko:K03801 ko00785,ko01100,map00785,map01100 - R07766,R07769 RC00039,RC00992,RC02867 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB CMS1_k127_3076959_2 1125973.JNLC01000002_gene1988 1.131e-148 494.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2TQND@28211|Alphaproteobacteria,3JQS8@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - 2.6.1.96 ko:K16871 ko00250,ko00650,ko01100,ko01120,map00250,map00650,map01100,map01120 M00027 R10178 RC00008,RC00062 ko00000,ko00001,ko00002,ko01000 - - - Aminotran_3 CMS1_k127_3076959_3 1238425.J07HQW2_03635 5.143e-139 462.0 COG0146@1|root,arCOG01512@2157|Archaea,2Y8DU@28890|Euryarchaeota,23S12@183963|Halobacteria 183963|Halobacteria E N-methylhydantoinase B acetone carboxylase, alpha subunit hyuB - 3.5.2.14 ko:K01474 ko00330,ko01100,map00330,map01100 - R03187 RC00632 ko00000,ko00001,ko01000 - - - Hydantoinase_B CMS1_k127_3076959_1 1343740.M271_44345 6.375e-160 527.0 COG0145@1|root,COG0145@2|Bacteria,2GIYE@201174|Actinobacteria 201174|Actinobacteria EQ PFAM Hydantoinase oxoprolinase - - 3.5.2.14,3.5.2.9 ko:K01469,ko:K01473 ko00330,ko00480,ko01100,map00330,map00480,map01100 - R00251,R03187 RC00553,RC00632 ko00000,ko00001,ko01000 - - - Hydant_A_N,Hydantoinase_A CMS1_k127_3076959_0 1411123.JQNH01000001_gene3587 5.112e-211 663.0 COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2TQND@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - - - - - - - - - - Aminotran_3 CMS1_k127_3076959_4 526222.Desal_2903 1.166e-22 100.0 2C477@1|root,32RDF@2|Bacteria,1RKW1@1224|Proteobacteria,42SWN@68525|delta/epsilon subdivisions,2WP88@28221|Deltaproteobacteria 28221|Deltaproteobacteria S DGC domain - - - - - - - - - - - - DGC CMS1_k127_308630_0 114615.BRADO6608 5.271e-133 426.0 COG0006@1|root,COG0006@2|Bacteria,1MVX5@1224|Proteobacteria,2TRMK@28211|Alphaproteobacteria,3JXT1@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - 3.4.13.9 ko:K01271 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 CMS1_k127_308630_3 1187851.A33M_0025 2.334e-34 136.0 COG1380@1|root,COG1380@2|Bacteria,1N753@1224|Proteobacteria,2UFFT@28211|Alphaproteobacteria,3FDGN@34008|Rhodovulum 28211|Alphaproteobacteria S LrgA family lrgA - - ko:K06518 - - - - ko00000,ko02000 1.E.14.2 - - LrgA CMS1_k127_308630_2 1187851.A33M_0024 8.085e-98 325.0 COG1346@1|root,COG1346@2|Bacteria,1MV81@1224|Proteobacteria,2TSP3@28211|Alphaproteobacteria,3FDAJ@34008|Rhodovulum 28211|Alphaproteobacteria M LrgB-like family lrgB - - - - - - - - - - - LrgB CMS1_k127_308630_1 172088.AUGA01000013_gene7367 4.038e-112 369.0 COG0654@1|root,COG0654@2|Bacteria,1MWWT@1224|Proteobacteria,2TRZP@28211|Alphaproteobacteria,3JWTI@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria CH FAD binding domain - - 1.14.13.1,1.14.13.114 ko:K00480,ko:K14974 ko00621,ko00624,ko00626,ko00760,ko01100,ko01120,ko01220,map00621,map00624,map00626,map00760,map01100,map01120,map01220 M00622 R00818,R05632,R06915,R06936,R06939,R08764 RC00115,RC00389 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3,NAD_binding_8 CMS1_k127_310082_0 1187851.A33M_3452 3.156e-278 863.0 COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2TQP0@28211|Alphaproteobacteria,3FCPG@34008|Rhodovulum 28211|Alphaproteobacteria P Oligopeptide/dipeptide transporter, C-terminal region yejF GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008144,GO:0008150,GO:0015399,GO:0015405,GO:0015833,GO:0015893,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035672,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042884,GO:0042886,GO:0042891,GO:0043167,GO:0043168,GO:0043492,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K02031,ko:K02032,ko:K13896 ko02010,ko02024,map02010,map02024 M00239,M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.21,3.A.1.5.24 - - ABC_tran,oligo_HPY CMS1_k127_310082_1 1197906.CAJQ02000052_gene4490 9.394e-163 516.0 COG4239@1|root,COG4239@2|Bacteria,1MUM5@1224|Proteobacteria,2TR1Y@28211|Alphaproteobacteria,3JSKV@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P N-terminal TM domain of oligopeptide transport permease C yejE GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0035672,GO:0042221,GO:0042493,GO:0042884,GO:0042886,GO:0042891,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944 - ko:K13895 ko02010,map02010 M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.21,3.A.1.5.24 - - BPD_transp_1,OppC_N CMS1_k127_3110791_2 316058.RPB_0998 7.233e-11 63.0 COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2TSB1@28211|Alphaproteobacteria,3JTWC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria EH Thiamine pyrophosphate enzyme, central domain MA20_00650 - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N CMS1_k127_3110791_1 1187851.A33M_0121 2.763e-62 225.0 COG1309@1|root,COG1309@2|Bacteria,1RJK5@1224|Proteobacteria,2TSES@28211|Alphaproteobacteria 28211|Alphaproteobacteria K PFAM regulatory protein TetR MA20_03880 - - - - - - - - - - - TetR_N CMS1_k127_3110791_0 113395.AXAI01000002_gene5219 3.296e-175 557.0 COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TTJ0@28211|Alphaproteobacteria,3JS5D@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - - - - - - - - - - GAF,GAF_2,HAMP,HATPase_c,HisKA,PAS_7,dCache_1 CMS1_k127_3116160_0 935261.JAGL01000019_gene596 1.9e-183 584.0 COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,2TSR0@28211|Alphaproteobacteria,43J3W@69277|Phyllobacteriaceae 28211|Alphaproteobacteria Q COG1233 Phytoene dehydrogenase and related - - - - - - - - - - - - Amino_oxidase,NAD_binding_8 CMS1_k127_3116160_2 1231190.NA8A_23834 3.562e-58 207.0 COG3476@1|root,COG3476@2|Bacteria,1MZC1@1224|Proteobacteria,2UBYB@28211|Alphaproteobacteria,43Q7M@69277|Phyllobacteriaceae 28211|Alphaproteobacteria T TspO/MBR family tspO - - ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 - - - ko00000,ko00001,ko02000 9.A.24 - - TspO_MBR CMS1_k127_3116160_1 670292.JH26_11480 5.919e-84 282.0 COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,1MVQY@1224|Proteobacteria,2U070@28211|Alphaproteobacteria,1JT5J@119045|Methylobacteriaceae 28211|Alphaproteobacteria K Cupin 2 conserved barrel domain protein - - - - - - - - - - - - Cupin_2,HTH_3,HTH_31 CMS1_k127_3116160_3 1336243.JAEA01000013_gene3244 4.225e-30 121.0 COG2335@1|root,COG2335@2|Bacteria,1RD06@1224|Proteobacteria,2U7H5@28211|Alphaproteobacteria,1JTC0@119045|Methylobacteriaceae 28211|Alphaproteobacteria M Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - - - - - - - - - - Fasciclin CMS1_k127_3116887_0 1120970.AUBZ01000009_gene2089 1.003e-111 367.0 COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,1RMR2@1236|Gammaproteobacteria,464J6@72275|Alteromonadaceae 1236|Gammaproteobacteria G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate glmM GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006464,GO:0006468,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008966,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0018130,GO:0019438,GO:0019538,GO:0034641,GO:0034654,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0046777,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576 5.4.2.10 ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 - R02060 RC00408 ko00000,ko00001,ko01000 - - iSBO_1134.SBO_3206 PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV CMS1_k127_3116887_1 1234364.AMSF01000016_gene1534 1.767e-100 339.0 COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,1RM8G@1236|Gammaproteobacteria,1X3ZA@135614|Xanthomonadales 135614|Xanthomonadales H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives folP - 2.5.1.15 ko:K00796 ko00790,ko01100,map00790,map01100 M00126,M00841 R03066,R03067 RC00121,RC00842 ko00000,ko00001,ko00002,ko01000 - - - Pterin_bind CMS1_k127_3116887_2 335283.Neut_0998 9.094e-53 190.0 COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,2VHEV@28216|Betaproteobacteria,372IS@32003|Nitrosomonadales 28216|Betaproteobacteria O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins ftsH GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41 CMS1_k127_3119022_1 1223521.BBJX01000002_gene2818 2.077e-37 145.0 COG0412@1|root,COG0412@2|Bacteria,1R3DI@1224|Proteobacteria,2VUJ3@28216|Betaproteobacteria 28216|Betaproteobacteria Q dienelactone hydrolase - - - - - - - - - - - - DLH CMS1_k127_3119022_0 1144319.PMI16_01348 0.0 1225.0 COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,2VH5H@28216|Betaproteobacteria,473GP@75682|Oxalobacteraceae 28216|Betaproteobacteria P Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity katG - 1.11.1.21 ko:K03782 ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110 - R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906 RC00034,RC00213,RC00767,RC02141 ko00000,ko00001,ko01000 - - - peroxidase CMS1_k127_3128019_1 765911.Thivi_0989 1.211e-74 262.0 COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,1RPNE@1236|Gammaproteobacteria,1WVYG@135613|Chromatiales 135613|Chromatiales I PFAM AMP-dependent synthetase - - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding CMS1_k127_3128019_0 716928.AJQT01000079_gene991 0.0 1234.0 COG0204@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TW3C@28211|Alphaproteobacteria,4BI55@82115|Rhizobiaceae 28211|Alphaproteobacteria IQ Phosphopantetheine attachment site - - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C_2,Acyltransferase,PP-binding CMS1_k127_3128019_8 1037409.BJ6T_62820 8.313e-10 66.0 2EQ6B@1|root,33HSN@2|Bacteria,1RJFQ@1224|Proteobacteria,2UBJY@28211|Alphaproteobacteria,3JZQB@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_3128019_10 648885.KB316284_gene4945 2.14e-05 55.0 COG2010@1|root,COG2010@2|Bacteria,1N8V1@1224|Proteobacteria,2UG8G@28211|Alphaproteobacteria,1JVEU@119045|Methylobacteriaceae 28211|Alphaproteobacteria C Cytochrome c, class I - - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 CMS1_k127_3128019_3 323098.Nwi_0402 1.86e-30 129.0 2E9WT@1|root,3342I@2|Bacteria,1NBEH@1224|Proteobacteria,2UFGC@28211|Alphaproteobacteria,3JZIT@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) MA20_00895 - - - - - - - - - - - PHA_gran_rgn CMS1_k127_3128019_5 1173026.Glo7428_2091 9.277e-29 122.0 COG0642@1|root,COG0784@1|root,COG2202@1|root,COG2203@1|root,COG3829@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,1G09B@1117|Cyanobacteria 1117|Cyanobacteria T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg CMS1_k127_3128019_7 1317124.DW2_00735 6.975e-14 78.0 COG2340@1|root,COG2340@2|Bacteria,1MZ84@1224|Proteobacteria,2UFSP@28211|Alphaproteobacteria,2XPF5@285107|Thioclava 28211|Alphaproteobacteria S Cysteine-rich secretory protein family MA20_18185 - - - - - - - - - - - CAP CMS1_k127_3128019_2 460265.Mnod_3630 2.99e-47 180.0 COG1376@1|root,COG1376@2|Bacteria,1MUAB@1224|Proteobacteria,2TTXM@28211|Alphaproteobacteria,1JU2J@119045|Methylobacteriaceae 28211|Alphaproteobacteria S PFAM ErfK YbiS YcfS YnhG family protein MA20_01915 - - - - - - - - - - - YkuD CMS1_k127_3128019_6 1038860.AXAP01000034_gene3878 2.285e-17 82.0 2E328@1|root,32Y2G@2|Bacteria,1N9RI@1224|Proteobacteria,2UFJ4@28211|Alphaproteobacteria,3K0VA@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_3128019_9 114615.BRADO3920 1.288e-05 48.0 COG4953@1|root,COG4953@2|Bacteria,1MUA9@1224|Proteobacteria,2TR2R@28211|Alphaproteobacteria,3JS2X@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Penicillin-Binding Protein C-terminus Family pbpC - 2.4.1.129 ko:K05367 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - BiPBP_C,Transgly,Transpeptidase CMS1_k127_3160900_10 1187851.A33M_0251 2.774e-42 165.0 COG5388@1|root,COG5388@2|Bacteria,1RCVG@1224|Proteobacteria,2U2IX@28211|Alphaproteobacteria,3FDHJ@34008|Rhodovulum 28211|Alphaproteobacteria S PAS domain - - - - - - - - - - - - PAS_5 CMS1_k127_3160900_5 1187851.A33M_0247 2.18e-90 302.0 28I3D@1|root,2Z876@2|Bacteria,1P0DR@1224|Proteobacteria,2TTG2@28211|Alphaproteobacteria 28211|Alphaproteobacteria S PFAM type IV pilus assembly PilZ MA20_31715 - - - - - - - - - - - PilZ CMS1_k127_3160900_6 1429916.X566_23695 3.107e-85 288.0 COG3672@1|root,COG3672@2|Bacteria,1NUXW@1224|Proteobacteria,2TTXC@28211|Alphaproteobacteria,3JV82@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Bacterial transglutaminase-like cysteine proteinase BTLCP MA20_31720 - - - - - - - - - - - Peptidase_C93 CMS1_k127_3160900_7 316058.RPB_2139 3.111e-70 248.0 COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,2U5GR@28211|Alphaproteobacteria,3JTNJ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Bacterial transferase hexapeptide (six repeats) MA20_32230 - - - - - - - - - - - Hexapep CMS1_k127_3160900_14 1040989.AWZU01000027_gene3092 6.551e-28 117.0 2DYTB@1|root,32V60@2|Bacteria,1RHCB@1224|Proteobacteria,2U9FA@28211|Alphaproteobacteria,3JZS9@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - MA20_32235 - - - - - - - - - - - - CMS1_k127_3160900_8 1187851.A33M_2102 3.988e-60 216.0 2D6JA@1|root,32TME@2|Bacteria,1MXVJ@1224|Proteobacteria,2TQNP@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_3160900_15 1134912.AJTV01000021_gene2994 4.44e-21 98.0 2E4B6@1|root,32Z6W@2|Bacteria,1N7QS@1224|Proteobacteria,2UFNH@28211|Alphaproteobacteria,36Z2M@31993|Methylocystaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF3126) MA20_32250 - - - - - - - - - - - DUF3126 CMS1_k127_3160900_1 1126627.BAWE01000005_gene5319 1.803e-137 442.0 COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,2TQQ5@28211|Alphaproteobacteria,3JWAU@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Serine acetyltransferase, N-terminal cysE GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009058,GO:0009069,GO:0009070,GO:0009314,GO:0009333,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016053,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.3.1.30 ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 M00021 R00586 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,SATase_N CMS1_k127_3160900_3 1187851.A33M_2953 3.11e-99 344.0 COG0596@1|root,COG0596@2|Bacteria,1MW2P@1224|Proteobacteria,2TSS3@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Alpha beta hydrolase MA20_32265 - 1.11.1.10 ko:K00433 - - - - ko00000,ko01000 - - - Abhydrolase_1 CMS1_k127_3160900_13 351607.Acel_0886 1.885e-32 144.0 COG0600@1|root,COG0600@2|Bacteria,2GP2J@201174|Actinobacteria,4EW2R@85013|Frankiales 201174|Actinobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K02050 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - BPD_transp_1 CMS1_k127_3160900_4 1187851.A33M_2952 5.042e-92 318.0 2AS1Y@1|root,31HEF@2|Bacteria,1R2Y6@1224|Proteobacteria,2TRKR@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_3160900_12 1126627.BAWE01000005_gene5326 5.762e-35 136.0 COG4391@1|root,COG4391@2|Bacteria,1MZNK@1224|Proteobacteria,2UD0H@28211|Alphaproteobacteria,3JZEI@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Zinc-finger domain MA20_32275 - - - - - - - - - - - zf-CHCC CMS1_k127_3160900_2 1187851.A33M_2950 1.206e-125 414.0 COG0654@1|root,COG0654@2|Bacteria,1MWWT@1224|Proteobacteria,2TRZP@28211|Alphaproteobacteria,3FDPR@34008|Rhodovulum 28211|Alphaproteobacteria CH FAD binding domain nah - 1.14.13.1 ko:K00480 ko00621,ko00624,ko00626,ko01100,ko01120,ko01220,map00621,map00624,map00626,map01100,map01120,map01220 - R00818,R05632,R06915,R06936,R06939 RC00389 ko00000,ko00001,ko01000 - - - FAD_binding_3 CMS1_k127_3160900_0 1038859.AXAU01000011_gene2594 1.866e-159 509.0 COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,2TTWK@28211|Alphaproteobacteria,3JS6D@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Cobalamin-independent synthase, Catalytic domain MA20_32395 - 2.1.1.14,4.4.1.23 ko:K00549,ko:K22363 ko00270,ko00450,ko00625,ko01100,ko01110,ko01230,map00270,map00450,map00625,map01100,map01110,map01230 M00017 R04405,R09365,R11897,R11899 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_2 CMS1_k127_3160900_11 504832.OCAR_7636 1.254e-38 154.0 COG1937@1|root,COG1937@2|Bacteria,1N9P2@1224|Proteobacteria,2UF3F@28211|Alphaproteobacteria,3JZE7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Metal-sensitive transcriptional repressor MA20_24475 - - ko:K21600 - - - - ko00000,ko03000 - - - Trns_repr_metal CMS1_k127_3160900_9 395494.Galf_2722 1.257e-43 163.0 28WAT@1|root,2ZIB9@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - CMS1_k127_3192469_1 1144312.PMI09_06009 1.69e-17 87.0 COG3698@1|root,COG3698@2|Bacteria,1NH9S@1224|Proteobacteria,2TT5B@28211|Alphaproteobacteria,4B8VH@82115|Rhizobiaceae 28211|Alphaproteobacteria S periplasmic protein - - - - - - - - - - - - NAGPA CMS1_k127_3192469_0 1500301.JQMF01000023_gene5528 3.113e-189 613.0 COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TTJ0@28211|Alphaproteobacteria,4BM4C@82115|Rhizobiaceae 28211|Alphaproteobacteria T GAF domain - - - - - - - - - - - - GAF,GAF_2,HAMP,HATPase_c,HisKA,dCache_1 CMS1_k127_3198327_8 1246995.AFR_13090 8.318e-09 59.0 COG0654@1|root,COG0654@2|Bacteria,2GKUZ@201174|Actinobacteria 201174|Actinobacteria CH COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - - - - - - - - - - FAD_binding_3 CMS1_k127_3198327_0 398525.KB900701_gene7357 1.866e-151 488.0 COG0346@1|root,COG0346@2|Bacteria,1MUWY@1224|Proteobacteria,2TTMJ@28211|Alphaproteobacteria,3JUBI@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - 1.13.11.2 ko:K00446 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 M00569 R00816,R04089,R05295,R05404,R05406,R07795 RC00387,RC00643,RC01075,RC01364,RC01914 br01602,ko00000,ko00001,ko00002,ko01000 - - - Glyoxalase CMS1_k127_3198327_6 479434.Sthe_2580 3.933e-43 169.0 COG0702@1|root,COG0702@2|Bacteria,2G78J@200795|Chloroflexi 200795|Chloroflexi GM PFAM NmrA family protein - - - - - - - - - - - - NmrA CMS1_k127_3198327_2 1040989.AWZU01000005_gene374 2.708e-122 406.0 COG5022@1|root,COG5022@2|Bacteria,1QU37@1224|Proteobacteria,2TVXC@28211|Alphaproteobacteria,3K6NA@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria Z motor activity - - - - - - - - - - - - - CMS1_k127_3198327_3 1429916.X566_03360 7.849e-86 287.0 COG5400@1|root,COG5400@2|Bacteria,1RASG@1224|Proteobacteria,2U590@28211|Alphaproteobacteria,3JSC3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF1134) MA20_46305 - - - - - - - - - - - DUF1134 CMS1_k127_3198327_7 196490.AUEZ01000006_gene5545 1.778e-41 159.0 COG3350@1|root,COG3350@2|Bacteria,1N0GC@1224|Proteobacteria,2UBRM@28211|Alphaproteobacteria,3JXT6@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S YHS domain protein - - - - - - - - - - - - YHS CMS1_k127_3198327_5 323097.Nham_3378 4.855e-76 264.0 COG1218@1|root,COG1218@2|Bacteria,1N0GY@1224|Proteobacteria,2TT7B@28211|Alphaproteobacteria,3JR4B@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P Inositol monophosphatase family cysQ - 3.1.3.7 ko:K01082 ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130 - R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03016 - - - Inositol_P CMS1_k127_3198327_4 1187851.A33M_2236 8.311e-78 276.0 COG5385@1|root,COG5385@2|Bacteria,1MVEY@1224|Proteobacteria,2TSE6@28211|Alphaproteobacteria,3FDG9@34008|Rhodovulum 28211|Alphaproteobacteria S Histidine phosphotransferase C-terminal domain MA20_46320 - - ko:K13588 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001 - - - HPTransfase CMS1_k127_3198327_1 1304877.KI519399_gene3389 1.252e-138 449.0 COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2TSN2@28211|Alphaproteobacteria,3JTYN@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Function of homologous gene experimentally demonstrated in an other organism cheA - 2.7.13.3 ko:K03407 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 - - - CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg CMS1_k127_3219794_3 383372.Rcas_4299 3.971e-24 111.0 COG0530@1|root,COG0530@2|Bacteria,2G7I2@200795|Chloroflexi 200795|Chloroflexi P PFAM sodium calcium exchanger membrane region - - - ko:K07301 - - - - ko00000,ko02000 2.A.19.5 - - Na_Ca_ex CMS1_k127_3219794_0 1458275.AZ34_11035 2.287e-150 481.0 COG3181@1|root,COG3181@2|Bacteria,1MXEX@1224|Proteobacteria,2VKSV@28216|Betaproteobacteria,4AC49@80864|Comamonadaceae 28216|Betaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC CMS1_k127_3219794_2 1037409.BJ6T_66100 2.175e-42 161.0 2BKYI@1|root,32FF5@2|Bacteria,1RB6X@1224|Proteobacteria,2VER9@28211|Alphaproteobacteria,3JY0I@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter TctB family MA20_15120 - - - - - - - - - - - TctB CMS1_k127_3219794_1 1038859.AXAU01000010_gene1751 1.174e-146 471.0 COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TR4Q@28211|Alphaproteobacteria,3JVYZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter TctA family MA20_15125 - - ko:K07793 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctA CMS1_k127_3239703_4 1040989.AWZU01000029_gene4329 4.622e-30 126.0 COG1396@1|root,COG1396@2|Bacteria,1MZQK@1224|Proteobacteria,2UCAK@28211|Alphaproteobacteria,3K0EH@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3,HTH_31 CMS1_k127_3239703_0 189753.AXAS01000003_gene4564 1.5e-315 982.0 COG0651@1|root,COG0651@2|Bacteria,1MXRW@1224|Proteobacteria,2TZIX@28211|Alphaproteobacteria,3JSF7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria CP Proton-conducting membrane transporter hyfB - - - - - - - - - - - Proton_antipo_M CMS1_k127_3239703_1 1040989.AWZU01000029_gene4327 1.836e-143 464.0 COG0650@1|root,COG0650@2|Bacteria,1MXV5@1224|Proteobacteria,2U0GZ@28211|Alphaproteobacteria,3JU8U@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C NADH dehydrogenase hycD - - - - - - - - - - - NADHdh CMS1_k127_3239703_2 398525.KB900701_gene3355 1.274e-101 351.0 COG4237@1|root,COG4237@2|Bacteria,1NAT8@1224|Proteobacteria,2TUAC@28211|Alphaproteobacteria,3JTK6@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C COG4237 Hydrogenase 4 membrane component (E) hyfE - - ko:K12140 - - - - ko00000,ko01000 - - - - CMS1_k127_3239703_3 1304877.KI519400_gene1384 3.243e-57 213.0 COG0651@1|root,COG0651@2|Bacteria,1MVBA@1224|Proteobacteria,2TSRU@28211|Alphaproteobacteria,3JWX4@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria CP Proton-conducting membrane transporter hyfF - - ko:K12141 - - - - ko00000,ko01000 - - - Proton_antipo_M CMS1_k127_3244447_2 329726.AM1_3560 6.589e-08 58.0 COG1396@1|root,COG1396@2|Bacteria,1G398@1117|Cyanobacteria 1117|Cyanobacteria K Transcriptional regulator - - - - - - - - - - - - HTH_3,HTH_31 CMS1_k127_3244447_0 566466.NOR53_396 2.91e-103 346.0 COG0491@1|root,COG0491@2|Bacteria,1P5NJ@1224|Proteobacteria,1S1CZ@1236|Gammaproteobacteria,1J740@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S COG0491 Zn-dependent hydrolases, including glyoxylases - - 3.5.2.6 ko:K17837 ko01501,map01501 - R06363 RC01499 ko00000,ko00001,ko01000 - - - Lactamase_B CMS1_k127_3244447_1 702113.PP1Y_AT6092 9.729e-09 57.0 COG2271@1|root,COG2271@2|Bacteria,1MWYR@1224|Proteobacteria,2TSXW@28211|Alphaproteobacteria,2K1KD@204457|Sphingomonadales 204457|Sphingomonadales G COG0477 Permeases of the major facilitator superfamily - - - - - - - - - - - - MFS_1 CMS1_k127_324821_0 1288963.ADIS_0251 1.241e-124 404.0 COG1082@1|root,COG1082@2|Bacteria 2|Bacteria G myo-inosose-2 dehydratase activity - - - - - - - - - - - - AP_endonuc_2 CMS1_k127_324821_1 332101.JIBU02000031_gene3172 3.909e-07 60.0 COG2138@1|root,COG2247@1|root,COG2138@2|Bacteria,COG2247@2|Bacteria,1V4KR@1239|Firmicutes,24A6B@186801|Clostridia,36GBT@31979|Clostridiaceae 186801|Clostridia M The GLUG motif - - - - - - - - - - - - CW_binding_2,Glug CMS1_k127_3268125_0 316056.RPC_2849 6.678e-153 495.0 COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2TQZE@28211|Alphaproteobacteria,3JRKV@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Peptidase family M23 MA20_30780 - - - - - - - - - - - Peptidase_M23 CMS1_k127_3268125_1 196490.AUEZ01000059_gene1111 3.091e-61 216.0 COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,2U6Z9@28211|Alphaproteobacteria,3JTEU@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O Redoxin bcp - 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - AhpC-TSA CMS1_k127_3286788_0 1187851.A33M_3629 3.219e-252 813.0 COG0457@1|root,COG0457@2|Bacteria,1N09H@1224|Proteobacteria,2TSKT@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Tetratricopeptide repeat - - - - - - - - - - - - - CMS1_k127_3290163_1 107636.JQNK01000006_gene963 3.132e-13 81.0 COG5433@1|root,COG5433@2|Bacteria,1NJCU@1224|Proteobacteria,2UKB3@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Transposase DDE domain group 1 - - - - - - - - - - - - DDE_Tnp_1_4 CMS1_k127_3290163_0 1121106.JQKB01000067_gene1792 2.971e-115 381.0 COG5433@1|root,COG5433@2|Bacteria,1MY25@1224|Proteobacteria,2U0Y8@28211|Alphaproteobacteria,2JVFX@204441|Rhodospirillales 204441|Rhodospirillales L Transposase DDE domain group 1 - - - - - - - - - - - - DDE_Tnp_1_4 CMS1_k127_3306189_1 1187851.A33M_0044 2.073e-74 254.0 28I53@1|root,2Z88I@2|Bacteria,1NE5N@1224|Proteobacteria,2TTBB@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF3750) - - - - - - - - - - - - DUF3750 CMS1_k127_3306189_0 1040989.AWZU01000012_gene1409 1.513e-133 440.0 COG5434@1|root,COG5434@2|Bacteria,1N3IG@1224|Proteobacteria,2U0A8@28211|Alphaproteobacteria,3JSMH@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Right handed beta helix region MA20_15840 - - - - - - - - - - - Beta_helix,Pectate_lyase_3 CMS1_k127_3306189_2 114615.BRADO2676 9.091e-10 61.0 COG2039@1|root,COG2039@2|Bacteria,1MWYG@1224|Proteobacteria,2TU8G@28211|Alphaproteobacteria,3JQYT@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O Removes 5-oxoproline from various penultimate amino acid residues except L-proline MA20_15835 - 3.4.19.3 ko:K01304 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C15 CMS1_k127_3309486_3 420324.KI911956_gene3388 2.034e-37 147.0 COG2940@1|root,COG2940@2|Bacteria,1MWFB@1224|Proteobacteria,2U05I@28211|Alphaproteobacteria 28211|Alphaproteobacteria S SET domain - - - ko:K07117 - - - - ko00000 - - - SET CMS1_k127_3309486_0 1238182.C882_0106 3.124e-102 344.0 COG2128@1|root,COG2128@2|Bacteria,1N82C@1224|Proteobacteria,2TSPV@28211|Alphaproteobacteria,2JU0E@204441|Rhodospirillales 204441|Rhodospirillales S Protein of unknown function (DUF3179) - - - - - - - - - - - - DUF3179 CMS1_k127_3309486_2 675635.Psed_1279 1.869e-46 181.0 COG2128@1|root,COG2128@2|Bacteria,2ICVV@201174|Actinobacteria,4E7X9@85010|Pseudonocardiales 201174|Actinobacteria S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - - - - - - - - - - CMD CMS1_k127_3309486_5 670307.HYPDE_27278 4.852e-21 97.0 2EKEB@1|root,33E4I@2|Bacteria,1NA5D@1224|Proteobacteria,2UHWF@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_3309486_1 187303.BN69_2562 2.904e-73 252.0 COG1376@1|root,COG1376@2|Bacteria,1MVYT@1224|Proteobacteria,2U5A0@28211|Alphaproteobacteria,36YA3@31993|Methylocystaceae 28211|Alphaproteobacteria S L,D-transpeptidase catalytic domain - - - ko:K16291 - - - - ko00000,ko01002,ko01011 - - - YkuD CMS1_k127_3309486_4 269796.Rru_A1705 1.805e-33 136.0 COG0797@1|root,COG0797@2|Bacteria,1MZ8S@1224|Proteobacteria,2TUER@28211|Alphaproteobacteria,2JQ68@204441|Rhodospirillales 204441|Rhodospirillales M Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides rlpA - - ko:K03642 - - - - ko00000 - - - DPBB_1,SPOR CMS1_k127_3309486_6 1038859.AXAU01000004_gene4436 2.116e-13 70.0 COG0684@1|root,COG0684@2|Bacteria,1MW9P@1224|Proteobacteria,2TTGT@28211|Alphaproteobacteria,3JTVV@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H Aldolase/RraA MA20_40110 - - ko:K02553 - - - - ko00000,ko03019 - - - RraA-like CMS1_k127_3320119_4 652103.Rpdx1_1676 3.759e-14 74.0 COG4961@1|root,COG4961@2|Bacteria,1N3XK@1224|Proteobacteria,2UBRJ@28211|Alphaproteobacteria,3JXUI@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria U TadE-like protein - - - ko:K02651 ko04112,map04112 - - - ko00000,ko00001,ko02035,ko02044 - - - TadE CMS1_k127_3320119_3 1038862.KB893862_gene2458 1.063e-27 120.0 COG4961@1|root,COG4961@2|Bacteria,1N744@1224|Proteobacteria,2UGR2@28211|Alphaproteobacteria,3JWHX@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria U TadE-like protein - - - - - - - - - - - - TadE CMS1_k127_3320119_1 1187851.A33M_3681 2.929e-75 255.0 COG1522@1|root,COG1522@2|Bacteria,1RDB3@1224|Proteobacteria,2U580@28211|Alphaproteobacteria,3FD6N@34008|Rhodovulum 28211|Alphaproteobacteria K helix_turn_helix ASNC type MA20_21975 - - ko:K05800 - - - - ko00000,ko03000 - - - AsnC_trans_reg,HTH_24,HTH_AsnC-type CMS1_k127_3320119_2 504832.OCAR_7547 9.989e-75 262.0 COG0524@1|root,COG0524@2|Bacteria,1MWX4@1224|Proteobacteria,2VF16@28211|Alphaproteobacteria,3JV89@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G Belongs to the carbohydrate kinase PfkB family - - - - - - - - - - - - PfkB CMS1_k127_3320119_0 1038858.AXBA01000007_gene1070 1.287e-105 346.0 COG2816@1|root,COG2816@2|Bacteria,1QGCX@1224|Proteobacteria,2TVMG@28211|Alphaproteobacteria,3EYBZ@335928|Xanthobacteraceae 28211|Alphaproteobacteria L NADH pyrophosphatase zinc ribbon domain nudC - 3.6.1.22 ko:K03426 ko00760,ko01100,ko04146,map00760,map01100,map04146 - R00103,R03004,R11104 RC00002 ko00000,ko00001,ko01000 - - - NUDIX,NUDIX-like,zf-NADH-PPase CMS1_k127_333299_4 1038858.AXBA01000002_gene3856 6.473e-08 55.0 COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,2TSK4@28211|Alphaproteobacteria,3F1BN@335928|Xanthobacteraceae 28211|Alphaproteobacteria E Belongs to the alpha-IPM synthase homocitrate synthase family MA20_26350 - 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 - - - HMGL-like,LeuA_dimer CMS1_k127_333299_1 1304878.AUGD01000002_gene2197 3.8e-66 231.0 COG0454@1|root,COG0454@2|Bacteria,1QUD7@1224|Proteobacteria,2U5MN@28211|Alphaproteobacteria,3JV1B@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K Acetyltransferase (GNAT) domain - - - ko:K03830 - - - - ko00000,ko01000 - - - Acetyltransf_10 CMS1_k127_333299_0 1411123.JQNH01000001_gene854 3.677e-211 664.0 COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,2TQQ1@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Belongs to the class-I aminoacyl-tRNA synthetase family cysS GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 ko:K01883 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_2,tRNA-synt_1e CMS1_k127_333299_3 1187851.A33M_1246 3.081e-27 114.0 2EAPA@1|root,334RR@2|Bacteria,1N1K3@1224|Proteobacteria,2UDBG@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_333299_2 258594.RPA4673 1.112e-36 139.0 COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,2TQUY@28211|Alphaproteobacteria,3JT70@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Metallo-beta-lactamase superfamily MA20_39390 - - - - - - - - - - - Lactamase_B CMS1_k127_3354799_1 883078.HMPREF9695_01849 9.759e-139 449.0 COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,2TS1P@28211|Alphaproteobacteria,3JSWY@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Belongs to the peptidase S11 family dacC - 3.4.16.4 ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 CMS1_k127_3354799_2 639283.Snov_1768 2.31e-81 281.0 COG0797@1|root,COG0797@2|Bacteria,1MZ8S@1224|Proteobacteria,2TUER@28211|Alphaproteobacteria,3EY5D@335928|Xanthobacteraceae 28211|Alphaproteobacteria M Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides rlpA - - ko:K03642 - - - - ko00000 - - - DPBB_1,SPOR CMS1_k127_3354799_3 1168059.KB899087_gene1061 1.561e-11 64.0 COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,3F0VP@335928|Xanthobacteraceae 28211|Alphaproteobacteria L Resolvase, N terminal domain - - - - - - - - - - - - Recombinase,Resolvase,Zn_ribbon_recom CMS1_k127_3354799_0 113395.AXAI01000002_gene5219 7.077e-250 797.0 COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TTJ0@28211|Alphaproteobacteria,3JS5D@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - - - - - - - - - - GAF,GAF_2,HAMP,HATPase_c,HisKA,PAS_7,dCache_1 CMS1_k127_3414739_1 189753.AXAS01000017_gene3070 2.048e-68 238.0 COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,2TRXE@28211|Alphaproteobacteria,3JQQ3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Belongs to the universal ribosomal protein uS2 family rpsB GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02967 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S2 CMS1_k127_3414739_0 883078.HMPREF9695_02023 9.522e-226 708.0 COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,2TSCN@28211|Alphaproteobacteria,3JQY6@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L DNA polymerase dnaE GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon CMS1_k127_3419130_2 1038860.AXAP01000080_gene1603 5.044e-77 268.0 COG0860@1|root,COG0860@2|Bacteria,1RJBG@1224|Proteobacteria,2TVMH@28211|Alphaproteobacteria,3JR6M@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M N-acetylmuramoyl-L-alanine amidase - - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3 CMS1_k127_3419130_0 1187851.A33M_0609 2.645e-124 411.0 COG2301@1|root,COG2301@2|Bacteria,1MW0A@1224|Proteobacteria,2TTC0@28211|Alphaproteobacteria,3FCZE@34008|Rhodovulum 28211|Alphaproteobacteria G HpcH/HpaI aldolase/citrate lyase family citE - 3.1.2.30,4.1.3.34 ko:K01644,ko:K14451 ko00630,ko01120,ko01200,ko02020,map00630,map01120,map01200,map02020 M00373 R00362,R10612 RC00004,RC00014,RC00067,RC01118 ko00000,ko00001,ko00002,ko01000 - - - HpcH_HpaI CMS1_k127_3419130_1 1123229.AUBC01000013_gene2512 4.269e-82 295.0 COG4923@1|root,COG4923@2|Bacteria,1MY1R@1224|Proteobacteria,2U4CU@28211|Alphaproteobacteria,3JRED@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF429) - - - - - - - - - - - - DUF429 CMS1_k127_3419130_3 338966.Ppro_1306 9.402e-63 232.0 COG4870@1|root,COG4870@2|Bacteria,1MV6S@1224|Proteobacteria,42P5Q@68525|delta/epsilon subdivisions,2WKD3@28221|Deltaproteobacteria,43TC9@69541|Desulfuromonadales 28221|Deltaproteobacteria O Papain family cysteine protease - - - - - - - - - - - - Peptidase_C1 CMS1_k127_350601_2 272560.BPSS2165 9.727e-51 182.0 COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,2VIQ7@28216|Betaproteobacteria,1K2DE@119060|Burkholderiaceae 28216|Betaproteobacteria M PFAM NAD-dependent epimerase dehydratase - - 1.1.1.219 ko:K00091 - - - - ko00000,ko01000 - - - Epimerase CMS1_k127_350601_1 426117.M446_6340 6.109e-89 306.0 COG3394@1|root,COG3394@2|Bacteria,1PP39@1224|Proteobacteria,2U2UW@28211|Alphaproteobacteria,1JRFB@119045|Methylobacteriaceae 28211|Alphaproteobacteria G TIGRFAM hopanoid biosynthesis associated protein HpnK - - 3.5.1.105 ko:K03478 - - - - ko00000,ko01000 - - - YdjC CMS1_k127_350601_0 460265.Mnod_7154 1.105e-239 748.0 COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,2TRFJ@28211|Alphaproteobacteria,1JS0K@119045|Methylobacteriaceae 28211|Alphaproteobacteria C TIGRFAM hopanoid biosynthesis associated radical SAM protein HpnJ - - - - - - - - - - - - Radical_SAM CMS1_k127_350910_0 568706.BN118_1403 2.413e-86 291.0 COG0726@1|root,COG0726@2|Bacteria,1MV3V@1224|Proteobacteria,2VJQR@28216|Betaproteobacteria,3T1FV@506|Alcaligenaceae 28216|Betaproteobacteria G Polysaccharide deacetylase - - 3.5.1.104 ko:K22278 - - - - ko00000,ko01000 - - - Polysacc_deac_1 CMS1_k127_350910_2 244447.XP_008321222.1 0.0002649 53.0 KOG1584@1|root,KOG1584@2759|Eukaryota,394HT@33154|Opisthokonta,3BI89@33208|Metazoa,3CWR8@33213|Bilateria,483TN@7711|Chordata,48V69@7742|Vertebrata,49XBG@7898|Actinopterygii 33208|Metazoa S Amine sulfotransferase-like - GO:0003674,GO:0003824,GO:0004062,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008146,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016782,GO:0034930,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0051923 2.8.2.1,2.8.2.2,2.8.2.3,2.8.2.4 ko:K01014,ko:K01015,ko:K01016,ko:K01025,ko:K16949 ko00140,ko05204,map00140,map05204 - R00629,R01242,R01861,R02350,R03405,R08977,R08978 RC00007,RC00128,RC00231,RC00341,RC00610 ko00000,ko00001,ko01000 - - - Sulfotransfer_1 CMS1_k127_350910_1 1123060.JONP01000009_gene2011 2.37e-57 205.0 COG0624@1|root,COG0624@2|Bacteria,1MUSU@1224|Proteobacteria,2TS6M@28211|Alphaproteobacteria,2JYJE@204441|Rhodospirillales 204441|Rhodospirillales E Peptidase dimerisation domain - - 3.4.17.11 ko:K01295 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 CMS1_k127_3526399_2 404380.Gbem_0061 2.762e-10 61.0 2DMNF@1|root,32SNT@2|Bacteria,1RA9F@1224|Proteobacteria 1224|Proteobacteria S FRG - - - - - - - - - - - - FRG CMS1_k127_3526399_0 1121861.KB899951_gene2301 1.461e-116 379.0 COG3039@1|root,COG3039@2|Bacteria,1MVDK@1224|Proteobacteria,2TS7B@28211|Alphaproteobacteria,2JQR2@204441|Rhodospirillales 28211|Alphaproteobacteria L Transposase - - - - - - - - - - - - DDE_Tnp_1,DUF772 CMS1_k127_3526399_1 1121861.KB899912_gene1160 2.418e-29 122.0 COG3039@1|root,COG3039@2|Bacteria 2|Bacteria L Transposase - - - - - - - - - - - - DDE_Tnp_1,DUF772 CMS1_k127_3529490_0 709797.CSIRO_2883 0.0 1137.0 COG1215@1|root,COG5309@1|root,COG1215@2|Bacteria,COG5309@2|Bacteria,1MWF8@1224|Proteobacteria,2VEZT@28211|Alphaproteobacteria,3JTNP@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Glycosyl transferase family 21 MA20_12920 - 2.4.1.12,3.2.1.58 ko:K00694,ko:K01210 ko00500,ko01100,ko02026,map00500,map01100,map02026 - R00308,R02889,R03115 RC00005,RC00467 ko00000,ko00001,ko01000,ko01003,ko02000 4.D.3.1.2,4.D.3.1.5,4.D.3.1.6 GT2 - Glyco_hydro_17,Glyco_tranf_2_3,Glyco_trans_2_3 CMS1_k127_3531622_1 1046724.KB889829_gene3064 3.691e-153 489.0 COG0155@1|root,COG0155@2|Bacteria,1MVVB@1224|Proteobacteria,1RMFH@1236|Gammaproteobacteria,46482@72275|Alteromonadaceae 1236|Gammaproteobacteria P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate cysI GO:0003674,GO:0003824,GO:0004783,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006790,GO:0008150,GO:0008152,GO:0009337,GO:0009987,GO:0016002,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016673,GO:0019419,GO:0020037,GO:0032991,GO:0044237,GO:0044424,GO:0044464,GO:0046906,GO:0048037,GO:0050311,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0097159,GO:1901363 1.8.1.2 ko:K00381 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R00858 RC00065 ko00000,ko00001,ko00002,ko01000 - - iEC55989_1330.EC55989_3037,iECH74115_1262.ECH74115_4017,iECIAI1_1343.ECIAI1_2867,iECNA114_1301.ECNA114_2794,iECO103_1326.ECO103_3307,iECSE_1348.ECSE_3019,iECSF_1327.ECSF_2552,iECSP_1301.ECSP_3712,iECUMN_1333.ECUMN_3091,iECW_1372.ECW_m2971,iECs_1301.ECs3618,iEKO11_1354.EKO11_1005,iEcE24377_1341.EcE24377A_3065,iSFV_1184.SFV_2742,iSbBS512_1146.SbBS512_E3112,iWFL_1372.ECW_m2971,iZ_1308.Z4073 NIR_SIR,NIR_SIR_ferr CMS1_k127_3531622_0 639283.Snov_4460 8.557e-174 558.0 COG0007@1|root,COG1648@1|root,COG0007@2|Bacteria,COG1648@2|Bacteria,1MUI0@1224|Proteobacteria,2TRJC@28211|Alphaproteobacteria,3EZ24@335928|Xanthobacteraceae 28211|Alphaproteobacteria H Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme cobA - 1.3.1.76,2.1.1.107,4.99.1.4 ko:K02302,ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02864,R03194,R03947 RC00003,RC00871,RC01012,RC01034 ko00000,ko00001,ko00002,ko01000 - - - CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase CMS1_k127_3545556_4 426117.M446_3101 2.146e-26 109.0 COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,2U3RS@28211|Alphaproteobacteria,1JRQJ@119045|Methylobacteriaceae 28211|Alphaproteobacteria H riboflavin synthase, alpha subunit ribE GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00066 RC00958,RC00960 ko00000,ko00001,ko00002,ko01000 - - - Lum_binding CMS1_k127_3545556_3 394.NGR_c09640 4.17e-49 181.0 COG0054@1|root,COG0054@2|Bacteria,1RD9J@1224|Proteobacteria,2U9IZ@28211|Alphaproteobacteria,4BEB3@82115|Rhizobiaceae 28211|Alphaproteobacteria H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin ribH GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R04457 RC00960 ko00000,ko00001,ko00002,ko01000 - - - DMRL_synthase CMS1_k127_3545556_2 1304877.KI519399_gene4836 4.346e-70 242.0 COG0781@1|root,COG0781@2|Bacteria,1RHFZ@1224|Proteobacteria,2UBQA@28211|Alphaproteobacteria,3JWKB@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons nusB - - ko:K03625 - - - - ko00000,ko03009,ko03021 - - - NusB CMS1_k127_3545556_0 1125973.JNLC01000017_gene3698 1.326e-108 361.0 COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,2TTI6@28211|Alphaproteobacteria,3JQYI@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 thiL - 2.7.4.16 ko:K00946 ko00730,ko01100,map00730,map01100 M00127 R00617 RC00002 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C CMS1_k127_3545556_1 1038858.AXBA01000001_gene3473 5.656e-98 337.0 COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,2TQNW@28211|Alphaproteobacteria 28211|Alphaproteobacteria C COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases lldD2 - 1.1.2.3,1.1.99.31 ko:K00101,ko:K15054 ko00620,ko00627,ko01100,ko01120,map00620,map00627,map01100,map01120 - R00196,R04160,R07664 RC00044,RC00240 ko00000,ko00001,ko01000 - - - FMN_dh CMS1_k127_354609_2 1187851.A33M_0352 1.155e-121 396.0 COG2240@1|root,COG2240@2|Bacteria,1MVC9@1224|Proteobacteria,2U2CH@28211|Alphaproteobacteria,3FEAQ@34008|Rhodovulum 28211|Alphaproteobacteria H Phosphomethylpyrimidine kinase pdxY - 2.7.1.35 ko:K00868 ko00750,ko01100,map00750,map01100 - R00174,R01909,R02493 RC00002,RC00017 ko00000,ko00001,ko01000 - - - Phos_pyr_kin CMS1_k127_354609_6 1073999.BN137_765 1.755e-13 76.0 COG2259@1|root,COG2259@2|Bacteria,1MZVP@1224|Proteobacteria,1S8UI@1236|Gammaproteobacteria 1236|Gammaproteobacteria S membrane yqjF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K15977 - - - - ko00000 - - - DoxX CMS1_k127_354609_0 709797.CSIRO_4010 2.126e-202 642.0 COG1174@1|root,COG1732@1|root,COG1174@2|Bacteria,COG1732@2|Bacteria,1MXA1@1224|Proteobacteria,2TUNH@28211|Alphaproteobacteria,3JTUK@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P Substrate binding domain of ABC-type glycine betaine transport system MA20_02380 - - ko:K05845,ko:K05846 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - BPD_transp_1,OpuAC CMS1_k127_354609_4 631454.N177_0065 1.646e-49 181.0 COG2010@1|root,COG2010@2|Bacteria,1MZSK@1224|Proteobacteria,2UC5Q@28211|Alphaproteobacteria,1JQ88@119043|Rhodobiaceae 28211|Alphaproteobacteria C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 CMS1_k127_354609_1 258594.RPA2035 2.818e-192 602.0 COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,2TRXI@28211|Alphaproteobacteria,3JT4K@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate ilvC - 1.1.1.86 ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R03051,R04439,R04440,R05068,R05069,R05071 RC00726,RC00836,RC00837,RC01726 ko00000,ko00001,ko00002,ko01000 - - - IlvC,IlvN CMS1_k127_354609_3 1040982.AXAL01000002_gene5728 2.258e-54 198.0 COG1280@1|root,COG1280@2|Bacteria,1RE3P@1224|Proteobacteria,2VG7C@28211|Alphaproteobacteria,43I5V@69277|Phyllobacteriaceae 28211|Alphaproteobacteria E PFAM Lysine exporter protein (LYSE YGGA) - - - - - - - - - - - - LysE CMS1_k127_354609_5 319003.Bra1253DRAFT_06580 1.019e-30 121.0 COG0440@1|root,COG0440@2|Bacteria,1RAGN@1224|Proteobacteria,2U5CW@28211|Alphaproteobacteria,3JS41@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Acetolactate synthase small subunit ilvH - 2.2.1.6 ko:K01653 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - ACT,ACT_5,ALS_ss_C CMS1_k127_3563520_1 1547437.LL06_07105 4.321e-10 62.0 COG1305@1|root,COG1305@2|Bacteria,1MWAI@1224|Proteobacteria,2TURT@28211|Alphaproteobacteria,43H12@69277|Phyllobacteriaceae 28211|Alphaproteobacteria E Transglutaminase/protease-like homologues - - - - - - - - - - - - Transglut_core CMS1_k127_3563520_0 1380355.JNIJ01000006_gene3041 5.42e-147 472.0 COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,2TQTP@28211|Alphaproteobacteria,3JR1M@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L PFAM transposase IS116 IS110 IS902 family - - - ko:K07486 - - - - ko00000 - - - DEDD_Tnp_IS110,Transposase_20 CMS1_k127_3575663_1 196490.AUEZ01000002_gene4337 1.155e-166 534.0 COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,2TQZB@28211|Alphaproteobacteria,3JS4R@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring ftsA - - ko:K03590 ko04112,map04112 - - - ko00000,ko00001,ko03036,ko04812 - - - FtsA,SHS2_FTSA CMS1_k127_3575663_0 883080.HMPREF9697_03869 1.732e-227 719.0 COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,2TS1Q@28211|Alphaproteobacteria,3JTNB@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity ftsZ - - ko:K03531 ko04112,map04112 - - - ko00000,ko00001,ko02048,ko03036,ko04812 - - - FtsZ_C,Tubulin CMS1_k127_3595413_2 316055.RPE_4389 1.465e-178 567.0 COG0044@1|root,COG0044@2|Bacteria,1MW10@1224|Proteobacteria,2TSQH@28211|Alphaproteobacteria,3JRZI@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria F Amidohydrolase family pyrC1 - 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 CMS1_k127_3595413_4 113395.AXAI01000001_gene2880 5.062e-107 354.0 COG0354@1|root,COG0354@2|Bacteria,1N852@1224|Proteobacteria,2TR8J@28211|Alphaproteobacteria,3JV0A@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Belongs to the GcvT family ygfZ - - ko:K06980 - - - - ko00000,ko03016 - - - GCV_T,GCV_T_C CMS1_k127_3595413_5 224911.27350809 4.623e-101 333.0 COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,2TUP5@28211|Alphaproteobacteria,3JR51@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L glycosylase i tag - 3.2.2.20 ko:K01246 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Adenine_glyco CMS1_k127_3595413_6 316057.RPD_1235 3.592e-85 293.0 COG1896@1|root,COG1896@2|Bacteria,1RACF@1224|Proteobacteria,2TUK3@28211|Alphaproteobacteria,3JS9G@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Metal dependent phosphohydrolases with conserved 'HD' motif. MA20_42120 - - ko:K06952 - - - - ko00000 - - - HD,HD_3 CMS1_k127_3595413_7 1038859.AXAU01000002_gene419 2.195e-59 210.0 COG5350@1|root,COG5350@2|Bacteria,1RDTX@1224|Proteobacteria,2U71X@28211|Alphaproteobacteria,3JV5K@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S protein tyrosine phosphatase MA20_42125 - - - - - - - - - - - DSPc,Y_phosphatase CMS1_k127_3595413_9 757424.Hsero_1267 5.972e-50 182.0 COG2050@1|root,COG2050@2|Bacteria,1RK46@1224|Proteobacteria,2VPWT@28216|Betaproteobacteria,475W2@75682|Oxalobacteraceae 28216|Betaproteobacteria Q Thioesterase superfamily - - - - - - - - - - - - 4HBT CMS1_k127_3595413_0 1238182.C882_1361 1.344e-270 844.0 COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2TSCY@28211|Alphaproteobacteria,2JQXF@204441|Rhodospirillales 204441|Rhodospirillales E COG0367 Asparagine synthase (glutamine-hydrolyzing) - - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 CMS1_k127_3595413_1 1238182.C882_1362 4.305e-210 670.0 COG0189@1|root,COG0454@1|root,COG0189@2|Bacteria,COG0456@2|Bacteria,1MVN2@1224|Proteobacteria,2TUT9@28211|Alphaproteobacteria,2JQH6@204441|Rhodospirillales 204441|Rhodospirillales HJK RimK-like ATP-grasp domain - - - - - - - - - - - - Acetyltransf_1,RimK CMS1_k127_3595413_3 1207063.P24_00880 1.194e-143 465.0 COG1363@1|root,COG1363@2|Bacteria,1MXEU@1224|Proteobacteria,2TSPX@28211|Alphaproteobacteria,2JQ84@204441|Rhodospirillales 204441|Rhodospirillales G M42 glutamyl aminopeptidase - - - - - - - - - - - - Peptidase_M42 CMS1_k127_3595413_10 1038860.AXAP01000051_gene5443 1.512e-37 147.0 2F6Z6@1|root,33ZF5@2|Bacteria,1MV4Y@1224|Proteobacteria,2TT12@28211|Alphaproteobacteria,3JTHQ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - MA20_42170 - - - - - - - - - - - - CMS1_k127_3595413_8 1038860.AXAP01000051_gene5442 7.235e-51 182.0 COG0604@1|root,COG0604@2|Bacteria,1MV3W@1224|Proteobacteria,2TRW7@28211|Alphaproteobacteria,3JQQ4@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Zinc-binding dehydrogenase MA20_42175 - - ko:K19745 ko00640,ko01100,map00640,map01100 - R00919 RC00095 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N CMS1_k127_3598007_8 211165.AJLN01000153_gene664 3.697e-16 80.0 COG1309@1|root,COG1309@2|Bacteria,1G5IR@1117|Cyanobacteria,1JKA7@1189|Stigonemataceae 1117|Cyanobacteria K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N CMS1_k127_3598007_4 1121033.AUCF01000011_gene1825 3.861e-22 105.0 2EBD7@1|root,335DY@2|Bacteria,1NCNQ@1224|Proteobacteria,2UIBP@28211|Alphaproteobacteria,2JY8R@204441|Rhodospirillales 204441|Rhodospirillales S Bacterial inner membrane protein - - - - - - - - - - - - Imp-YgjV CMS1_k127_3598007_0 1461694.ATO9_22530 5.508e-58 207.0 COG0454@1|root,COG0456@2|Bacteria,1QUS0@1224|Proteobacteria,2TXDS@28211|Alphaproteobacteria 28211|Alphaproteobacteria K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - - - - - - - - - - Acetyltransf_1 CMS1_k127_3598007_12 1245469.S58_06040 0.0006108 48.0 COG2010@1|root,COG2010@2|Bacteria,1N2E0@1224|Proteobacteria,2UDX6@28211|Alphaproteobacteria,3K0UC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - - - - - - - - - - - CMS1_k127_3598007_6 211114.JOEF01000062_gene1824 1.896e-17 92.0 COG0251@1|root,COG0251@2|Bacteria,2IHQ7@201174|Actinobacteria,4E715@85010|Pseudonocardiales 201174|Actinobacteria J Endoribonuclease L-PSP - - - - - - - - - - - - Ribonuc_L-PSP CMS1_k127_3598007_2 316056.RPC_2157 5.386e-45 168.0 COG1917@1|root,COG1917@2|Bacteria,1RHMM@1224|Proteobacteria,2U9W3@28211|Alphaproteobacteria,3K0B4@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Cupin domain - - - - - - - - - - - - Cupin_2 CMS1_k127_3598007_10 426117.M446_0584 3.038e-13 72.0 2EHBN@1|root,33B3H@2|Bacteria,1NH2U@1224|Proteobacteria,2UJFA@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_3598007_5 1134912.AJTV01000012_gene476 6.533e-18 87.0 2EHBN@1|root,33B3H@2|Bacteria,1NH2U@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - CMS1_k127_3598007_7 1297863.APJF01000001_gene2288 1.033e-16 83.0 29G04@1|root,302XX@2|Bacteria,1N9KT@1224|Proteobacteria,2UHEY@28211|Alphaproteobacteria,3K1DV@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - MA20_27245 - - - - - - - - - - - - CMS1_k127_3598007_9 1156919.QWC_19530 5.515e-16 83.0 2E46A@1|root,32Z28@2|Bacteria,1N6V5@1224|Proteobacteria,2VWQU@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_3598007_1 1248916.ANFY01000007_gene2565 3.618e-57 211.0 COG0596@1|root,COG0596@2|Bacteria,1Q47F@1224|Proteobacteria,2V788@28211|Alphaproteobacteria,2KBJW@204457|Sphingomonadales 204457|Sphingomonadales S hydrolases or acyltransferases, alpha beta hydrolase superfamily - - - - - - - - - - - - - CMS1_k127_3598007_3 1232437.KL662006_gene4388 7.992e-29 119.0 2C477@1|root,32RDF@2|Bacteria,1RKW1@1224|Proteobacteria,42SWN@68525|delta/epsilon subdivisions,2WP88@28221|Deltaproteobacteria 28221|Deltaproteobacteria S DGC domain - - - - - - - - - - - - DGC CMS1_k127_3600184_5 224911.27353463 1.749e-14 75.0 COG3293@1|root,COG3293@2|Bacteria,1P5HD@1224|Proteobacteria,2TUQI@28211|Alphaproteobacteria,3JZFP@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L Transposase DDE domain - - - - - - - - - - - - DDE_Tnp_1_2,DUF4096 CMS1_k127_3600184_6 1500301.JQMF01000005_gene3982 7.742e-08 54.0 COG3293@1|root,COG3293@2|Bacteria,1P5HD@1224|Proteobacteria,2TUQI@28211|Alphaproteobacteria,4BDQ5@82115|Rhizobiaceae 28211|Alphaproteobacteria L Transposase and inactivated - - - - - - - - - - - - DDE_Tnp_1_2,DUF4096 CMS1_k127_3600184_0 323097.Nham_2534 3.891e-134 439.0 COG3920@1|root,COG3920@2|Bacteria,1R720@1224|Proteobacteria,2U202@28211|Alphaproteobacteria,3JXV2@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Histidine kinase - - 2.1.1.80 ko:K00575 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko01000,ko02035 - - - HATPase_c,HATPase_c_2,HisKA_2,PAS,PAS_4 CMS1_k127_3600184_1 1037409.BJ6T_30630 1.432e-90 304.0 COG0664@1|root,COG0664@2|Bacteria,1MV7G@1224|Proteobacteria,2U1I4@28211|Alphaproteobacteria,3JUCQ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K Transcriptional regulator, Crp Fnr family - - - - - - - - - - - - HTH_Crp_2,cNMP_binding CMS1_k127_3600184_2 883078.HMPREF9695_03624 8.274e-50 183.0 COG0537@1|root,COG0537@2|Bacteria,1MZVD@1224|Proteobacteria,2UC00@28211|Alphaproteobacteria,3JY2G@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria FG HIT domain MA20_21960 - - - - - - - - - - - HIT CMS1_k127_3600184_3 469383.Cwoe_4341 5.237e-40 159.0 COG0388@1|root,COG0388@2|Bacteria 2|Bacteria S hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds - - 3.4.13.22 ko:K08641,ko:K11206 ko01502,ko02020,map01502,map02020 M00651 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 - - - CN_hydrolase,Peptidase_M15 CMS1_k127_3600184_4 438753.AZC_0140 5.741e-21 98.0 COG2816@1|root,COG2816@2|Bacteria,1QGCX@1224|Proteobacteria,2TVMG@28211|Alphaproteobacteria,3EYBZ@335928|Xanthobacteraceae 28211|Alphaproteobacteria L NADH pyrophosphatase zinc ribbon domain nudC - 3.6.1.22 ko:K03426 ko00760,ko01100,ko04146,map00760,map01100,map04146 - R00103,R03004,R11104 RC00002 ko00000,ko00001,ko01000 - - - NUDIX,NUDIX-like,zf-NADH-PPase CMS1_k127_3602093_0 330214.NIDE0553 3.738e-81 306.0 COG3210@1|root,COG3210@2|Bacteria 2|Bacteria U domain, Protein - - - - - - - - - - - - Haemagg_act CMS1_k127_3602093_1 330214.NIDE1953 1.1e-25 113.0 COG2831@1|root,COG2831@2|Bacteria 2|Bacteria U hemolysin activation secretion protein - - - - - - - - - - - - DUF285,POTRA_2,ShlB CMS1_k127_3604228_13 1187851.A33M_0252 4.468e-84 286.0 COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,2TSJG@28211|Alphaproteobacteria 28211|Alphaproteobacteria S membrane protein (homolog of Drosophila rhomboid) MA20_31620 - - - - - - - - - - - Rhomboid CMS1_k127_3604228_26 1038866.KB902813_gene1992 1.169e-44 167.0 COG0517@1|root,COG0517@2|Bacteria,1N0H3@1224|Proteobacteria,2UC0F@28211|Alphaproteobacteria,3JY3F@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Domain in cystathionine beta-synthase and other proteins. MA20_31615 - - - - - - - - - - - CBS CMS1_k127_3604228_6 883078.HMPREF9695_02537 5.867e-124 406.0 COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,2TVQR@28211|Alphaproteobacteria,3JS5E@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Patatin-like phospholipase rssA GO:0003674,GO:0003824,GO:0016787 - ko:K07001 - - - - ko00000 - - - Patatin CMS1_k127_3604228_17 1411123.JQNH01000001_gene1750 1.658e-75 258.0 COG1853@1|root,COG1853@2|Bacteria,1MUPP@1224|Proteobacteria,2TT7S@28211|Alphaproteobacteria 28211|Alphaproteobacteria S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family MA20_44860 - - - - - - - - - - - Flavin_Reduct CMS1_k127_3604228_14 1429916.X566_23630 7.282e-81 273.0 COG0778@1|root,COG0778@2|Bacteria,1PKUV@1224|Proteobacteria,2U5MZ@28211|Alphaproteobacteria,3JRWH@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Nitroreductase family MA20_31560 - - - - - - - - - - - Nitroreductase CMS1_k127_3604228_1 1231392.OCGS_0272 1.552e-279 867.0 COG3119@1|root,COG3119@2|Bacteria,1MV0B@1224|Proteobacteria,2TRI6@28211|Alphaproteobacteria 28211|Alphaproteobacteria P COG3119 Arylsulfatase A and related enzymes MA20_44000 - - - - - - - - - - - DUF4976,Sulfatase CMS1_k127_3604228_4 1231392.OCGS_0274 1.142e-159 518.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQNK@28211|Alphaproteobacteria 28211|Alphaproteobacteria G COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - - - - - - - - - - DctM CMS1_k127_3604228_27 1231392.OCGS_0275 8.279e-29 122.0 COG3090@1|root,COG3090@2|Bacteria 2|Bacteria G Trap-type c4-dicarboxylate transport system, small permease component - - - ko:K11689 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.56.1 - - DctQ CMS1_k127_3604228_16 1231392.OCGS_0273 1.806e-78 275.0 COG1638@1|root,COG1638@2|Bacteria,1MVHI@1224|Proteobacteria,2TRHD@28211|Alphaproteobacteria 28211|Alphaproteobacteria G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - - - - - - - - - - DctP CMS1_k127_3604228_23 1156935.QWE_04498 1.763e-52 198.0 COG0583@1|root,COG0583@2|Bacteria,1R6BU@1224|Proteobacteria,2U3I2@28211|Alphaproteobacteria,4BBV8@82115|Rhizobiaceae 28211|Alphaproteobacteria K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate CMS1_k127_3604228_8 1429916.X566_23640 1.128e-116 386.0 28NPA@1|root,2ZBP8@2|Bacteria,1R9WM@1224|Proteobacteria,2U197@28211|Alphaproteobacteria,3K6U8@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_3604228_19 652103.Rpdx1_4838 3.261e-69 244.0 COG1877@1|root,COG1877@2|Bacteria,1RGY2@1224|Proteobacteria,2U9NF@28211|Alphaproteobacteria,3JS8I@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G Removes the phosphate from trehalose 6-phosphate to produce free trehalose otsB - 3.1.3.12 ko:K01087 ko00500,ko01100,map00500,map01100 - R02778 RC00017 ko00000,ko00001,ko01000 - - - Trehalose_PPase CMS1_k127_3604228_3 438753.AZC_0482 5.656e-184 586.0 COG0380@1|root,COG0380@2|Bacteria,1MUIY@1224|Proteobacteria,2TQMP@28211|Alphaproteobacteria,3EYAW@335928|Xanthobacteraceae 28211|Alphaproteobacteria G Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor otsA - 2.4.1.15,2.4.1.347 ko:K00697 ko00500,ko01100,map00500,map01100 - R02737 RC00005,RC00049,RC02748 ko00000,ko00001,ko01000,ko01003 - GT20 - Glyco_transf_20 CMS1_k127_3604228_28 1304877.KI519400_gene485 2.84e-27 114.0 COG2010@1|root,COG2010@2|Bacteria,1NBAR@1224|Proteobacteria,2UHUQ@28211|Alphaproteobacteria,3K16V@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Cytochrome c cycB GO:0005575,GO:0005623,GO:0042597,GO:0044464 - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 CMS1_k127_3604228_0 196490.AUEZ01000066_gene2439 0.0 1127.0 COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,2TQWI@28211|Alphaproteobacteria,3JRSX@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS - 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD CMS1_k127_3604228_25 883080.HMPREF9697_00245 6.349e-45 165.0 COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,2UFKH@28211|Alphaproteobacteria,3JZFD@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Could be involved in insertion of integral membrane proteins into the membrane yidD - - ko:K08998 - - - - ko00000 - - - Haemolytic CMS1_k127_3604228_12 1187851.A33M_2680 2.51e-87 305.0 COG3904@1|root,COG3904@2|Bacteria,1QG8N@1224|Proteobacteria,2U0GJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S periplasmic protein - - - - - - - - - - - - - CMS1_k127_3604228_20 288000.BBta_5184 1.151e-68 238.0 COG0822@1|root,COG0822@2|Bacteria,1RDGB@1224|Proteobacteria,2U74A@28211|Alphaproteobacteria,3JRJR@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C NifU-like N terminal domain nifU - - - - - - - - - - - NifU_N CMS1_k127_3604228_11 1040989.AWZU01000027_gene3062 1.619e-88 299.0 COG0302@1|root,COG0302@2|Bacteria,1MY3N@1224|Proteobacteria,2TSZI@28211|Alphaproteobacteria,3JSEC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H GTP cyclohydrolase folE GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 - - - GTP_cyclohydroI CMS1_k127_3604228_22 1429916.X566_23585 1.059e-57 205.0 COG0139@1|root,COG0139@2|Bacteria,1MW67@1224|Proteobacteria,2UCKH@28211|Alphaproteobacteria,3JY07@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP hisI - 3.5.4.19,3.6.1.31 ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037 RC00002,RC01055 ko00000,ko00001,ko00002,ko01000 - - - PRA-CH,PRA-PH CMS1_k127_3604228_5 351348.Maqu_2864 8.966e-142 462.0 COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,1RQ50@1236|Gammaproteobacteria,46524@72275|Alteromonadaceae 1236|Gammaproteobacteria C COG0665 Glycine D-amino acid oxidases (deaminating) dadA - 1.4.5.1 ko:K00285 ko00360,map00360 - R01374,R09493 RC00006,RC00025 ko00000,ko00001,ko01000 - - - DAO CMS1_k127_3604228_15 1380394.JADL01000003_gene5040 6.932e-79 271.0 COG1024@1|root,COG1024@2|Bacteria,1PU1Q@1224|Proteobacteria,2TSW6@28211|Alphaproteobacteria,2JS2P@204441|Rhodospirillales 204441|Rhodospirillales I Enoyl-CoA hydratase/isomerase - - - - - - - - - - - - ECH_1 CMS1_k127_3604228_9 1187851.A33M_0202 3.328e-114 374.0 COG2301@1|root,COG2301@2|Bacteria,1MW0A@1224|Proteobacteria,2TTC0@28211|Alphaproteobacteria,3FE3T@34008|Rhodovulum 28211|Alphaproteobacteria G C-C_Bond_Lyase of the TIM-Barrel fold - - 4.1.3.34 ko:K01644 ko02020,map02020 - R00362 RC00067,RC01118 ko00000,ko00001,ko01000 - - - HpcH_HpaI CMS1_k127_3604228_18 1502851.FG93_03870 1.313e-74 271.0 COG2030@1|root,COG2030@2|Bacteria,1MW4N@1224|Proteobacteria,2U7FW@28211|Alphaproteobacteria,3K66C@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I MaoC like domain - - - - - - - - - - - - MaoC_dehydratas CMS1_k127_3604228_21 316058.RPB_2186 2.845e-66 239.0 COG0741@1|root,COG0741@2|Bacteria,1MUMA@1224|Proteobacteria,2TSA5@28211|Alphaproteobacteria,3JQZY@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M transglycosylase - - - - - - - - - - - - SLT CMS1_k127_3604228_7 196490.AUEZ01000066_gene2458 2.202e-117 390.0 COG5330@1|root,COG5330@2|Bacteria,1MXBZ@1224|Proteobacteria,2TT9C@28211|Alphaproteobacteria,3JR7Z@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Uncharacterised protein conserved in bacteria (DUF2336) MA20_31465 - - - - - - - - - - - DUF2336 CMS1_k127_3604228_24 1197906.CAJQ02000038_gene4674 2.134e-48 185.0 COG2198@1|root,COG2198@2|Bacteria,1NENQ@1224|Proteobacteria,2TSW1@28211|Alphaproteobacteria,3JQP2@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Histidine Phosphotransfer domain MA20_31460 - - - - - - - - - - - Hpt CMS1_k127_3604228_10 1187851.A33M_2478 2.817e-89 297.0 COG0784@1|root,COG0784@2|Bacteria,1N0NS@1224|Proteobacteria,2TV2S@28211|Alphaproteobacteria 28211|Alphaproteobacteria T Response regulator receiver MA20_31455 - - - - - - - - - - - Response_reg CMS1_k127_3604228_29 1187851.A33M_3589 1.752e-14 76.0 29A3V@1|root,2ZX51@2|Bacteria,1N1FQ@1224|Proteobacteria,2UDE2@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - MA20_05540 - - - - - - - - - - - - CMS1_k127_3604228_2 1028801.RG1141_PA14100 5.114e-208 661.0 COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2TQVK@28211|Alphaproteobacteria,4BNUF@82115|Rhizobiaceae 28211|Alphaproteobacteria C Molybdopterin-binding domain of aldehyde dehydrogenase - - - - - - - - - - - - Ald_Xan_dh_C2 CMS1_k127_3606855_2 674977.VMC_41810 9.397e-15 86.0 COG1361@1|root,COG1361@2|Bacteria,1MUQC@1224|Proteobacteria,1T39T@1236|Gammaproteobacteria,1XUYV@135623|Vibrionales 135623|Vibrionales M Gametolysin peptidase M11 - - - - - - - - - - - - NPCBM_assoc,Peptidase_M11 CMS1_k127_3606855_0 1366050.N234_33445 1.371e-81 281.0 COG3145@1|root,COG3145@2|Bacteria,1N5HB@1224|Proteobacteria,2VHNU@28216|Betaproteobacteria,1K2E9@119060|Burkholderiaceae 28216|Betaproteobacteria L Alkylated DNA repair protein alkB - 1.14.11.33 ko:K03919 - - - - ko00000,ko01000,ko03400 - - - 2OG-FeII_Oxy_2 CMS1_k127_3606855_1 28072.Nos7524_3008 1.05e-31 134.0 COG0642@1|root,COG0784@1|root,COG2202@1|root,COG3452@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3452@2|Bacteria,COG5002@2|Bacteria,1G09B@1117|Cyanobacteria,1HMEM@1161|Nostocales 1117|Cyanobacteria T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - CHASE,GAF,HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Response_reg CMS1_k127_3614662_1 666684.AfiDRAFT_1147 1.88e-159 506.0 COG3181@1|root,COG3181@2|Bacteria,1MXEX@1224|Proteobacteria,2TT5Y@28211|Alphaproteobacteria,3JT2E@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter family receptor MA20_15115 - - ko:K07795 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctC CMS1_k127_3614662_0 1089552.KI911559_gene3348 2.468e-224 705.0 COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TR4Q@28211|Alphaproteobacteria,2JPTU@204441|Rhodospirillales 204441|Rhodospirillales S Tripartite tricarboxylate transporter TctA family - - - - - - - - - - - - TctA CMS1_k127_3614662_6 1089552.KI911559_gene3349 6.992e-43 163.0 2B2JS@1|root,31V51@2|Bacteria,1QT11@1224|Proteobacteria,2VAWF@28211|Alphaproteobacteria,2JY2A@204441|Rhodospirillales 204441|Rhodospirillales S Tripartite tricarboxylate transporter TctB family - - - - - - - - - - - - TctB CMS1_k127_3614662_2 488538.SAR116_1208 4.24e-134 434.0 COG3181@1|root,COG3181@2|Bacteria,1MXEX@1224|Proteobacteria,2TT5Y@28211|Alphaproteobacteria,4BRQ7@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter family receptor MA20_43200 - - ko:K07795 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctC CMS1_k127_3614662_7 743836.AYNA01000052_gene52 7.769e-08 58.0 COG1376@1|root,COG1376@2|Bacteria,1Q823@1224|Proteobacteria,2TV64@28211|Alphaproteobacteria,36ZRF@31993|Methylocystaceae 28211|Alphaproteobacteria S L,D-transpeptidase catalytic domain - - - - - - - - - - - - YkuD CMS1_k127_3614662_5 504832.OCAR_7270 4.131e-43 165.0 2C86A@1|root,32VZQ@2|Bacteria,1MUVK@1224|Proteobacteria,2U1E4@28211|Alphaproteobacteria,3JS19@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - MA20_05890 - - - - - - - - - - - - CMS1_k127_3614662_4 1211115.ALIQ01000236_gene2478 1.309e-88 295.0 COG1376@1|root,COG1376@2|Bacteria,1MVYT@1224|Proteobacteria,2U60K@28211|Alphaproteobacteria 28211|Alphaproteobacteria S ErfK YbiS YcfS YnhG family protein MA20_22765 - - - - - - - - - - - YkuD CMS1_k127_3614662_3 1121861.KB899919_gene2758 9.959e-99 329.0 COG1053@1|root,COG1053@2|Bacteria,1MX5A@1224|Proteobacteria,2TV7T@28211|Alphaproteobacteria,2JXCI@204441|Rhodospirillales 204441|Rhodospirillales C FAD binding domain - - - - - - - - - - - - FAD_binding_2 CMS1_k127_361616_10 189753.AXAS01000035_gene1281 4.819e-50 179.0 COG2203@1|root,COG4191@1|root,COG5002@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,COG5002@2|Bacteria,1RCM9@1224|Proteobacteria,2TTJ0@28211|Alphaproteobacteria,3K6MV@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Cache domain - - - - - - - - - - - - GAF,GAF_2,HAMP,HATPase_c,HisKA,dCache_1 CMS1_k127_361616_6 1187851.A33M_3976 3.659e-92 309.0 COG1329@1|root,COG1329@2|Bacteria,1MWI2@1224|Proteobacteria,2TTVP@28211|Alphaproteobacteria,3FD0P@34008|Rhodovulum 28211|Alphaproteobacteria K CarD-like/TRCF domain carD - - ko:K07736 - - - - ko00000,ko03000 - - - CarD_CdnL_TRCF CMS1_k127_361616_9 266779.Meso_3378 1.029e-63 221.0 COG1146@1|root,COG1146@2|Bacteria,1RH5I@1224|Proteobacteria,2U98K@28211|Alphaproteobacteria,43K14@69277|Phyllobacteriaceae 28211|Alphaproteobacteria C Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions fdxA - - ko:K05524 - - - - ko00000 - - - DUF3470,Fer4,Fer4_4 CMS1_k127_361616_13 196490.AUEZ01000040_gene6071 6.006e-30 123.0 COG1188@1|root,COG1188@2|Bacteria,1MZR6@1224|Proteobacteria,2UBS3@28211|Alphaproteobacteria,3K08V@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J S4 domain hslR - - ko:K04762 - - - - ko00000,ko03110 - - - S4 CMS1_k127_361616_0 1187851.A33M_3980 0.0 1322.0 COG4581@1|root,COG4581@2|Bacteria,1MVD6@1224|Proteobacteria,2TR7N@28211|Alphaproteobacteria,3FCRP@34008|Rhodovulum 28211|Alphaproteobacteria L helicase superfamily c-terminal domain mgpS - 3.6.4.13 ko:K17675 - - - - ko00000,ko01000,ko03029 - - - Helicase_C CMS1_k127_361616_7 258594.RPA0492 1.473e-86 295.0 COG3064@1|root,COG3064@2|Bacteria,1NAWA@1224|Proteobacteria,2TSQY@28211|Alphaproteobacteria,3JUF1@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Protein of unknown function (DUF3108) - - - - - - - - - - - - DUF3108 CMS1_k127_361616_11 438753.AZC_0547 5.36e-39 147.0 COG0227@1|root,COG0227@2|Bacteria,1MZ57@1224|Proteobacteria,2UBQU@28211|Alphaproteobacteria,3EZZG@335928|Xanthobacteraceae 28211|Alphaproteobacteria J structural constituent of ribosome rpmB GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02902 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L28 CMS1_k127_361616_5 709797.CSIRO_0642 1.285e-98 342.0 COG4246@1|root,COG4246@2|Bacteria,1N7Y1@1224|Proteobacteria,2TTZW@28211|Alphaproteobacteria,3JTKP@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Esterase-like activity of phytase - - - - - - - - - - - - Phytase-like CMS1_k127_361616_1 1304877.KI519400_gene1835 6.267e-302 937.0 COG4547@1|root,COG4547@2|Bacteria,1MX11@1224|Proteobacteria,2TS4N@28211|Alphaproteobacteria,3JRPW@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H Cobalamin biosynthesis protein CobT VWA domain cobT - 6.6.1.2 ko:K09883 ko00860,ko01100,map00860,map01100 - R05227 RC02000 ko00000,ko00001,ko01000 - - - CobT,CobT_C CMS1_k127_361616_2 1187851.A33M_3971 1.632e-198 620.0 COG0714@1|root,COG0714@2|Bacteria,1MXIW@1224|Proteobacteria,2TS1Z@28211|Alphaproteobacteria,3FCFS@34008|Rhodovulum 28211|Alphaproteobacteria S Cobaltochelatase CobS subunit N terminal cobS - 6.6.1.2 ko:K09882 ko00860,ko01100,map00860,map01100 - R05227 RC02000 ko00000,ko00001,ko01000 - - - AAA_5,CbbQ_C,CobS_N CMS1_k127_361616_8 1125973.JNLC01000013_gene4036 4.243e-81 274.0 COG2214@1|root,COG2214@2|Bacteria,1MXTG@1224|Proteobacteria,2TRZH@28211|Alphaproteobacteria,3JRXF@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O DnaJ molecular chaperone homology domain - - - - - - - - - - - - DnaJ CMS1_k127_361616_12 189753.AXAS01000018_gene3320 5.8e-38 145.0 COG0271@1|root,COG0271@2|Bacteria,1MZG5@1224|Proteobacteria,2UF6U@28211|Alphaproteobacteria,3K0BM@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Belongs to the BolA IbaG family bolA GO:0006807,GO:0008150,GO:0008152,GO:0010467,GO:0019538,GO:0043170,GO:0044238,GO:0051604,GO:0071704,GO:0097428,GO:0106035,GO:1901564 - ko:K05527,ko:K22066 - - - - ko00000,ko03000,ko03029 - - - BolA CMS1_k127_361616_3 443598.AUFA01000014_gene6904 4.2e-179 573.0 COG4536@1|root,COG4536@2|Bacteria,1NZ99@1224|Proteobacteria,2TVZH@28211|Alphaproteobacteria,3JT6I@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P Transporter associated domain corB GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03699 - - - - ko00000,ko02042 - - - CBS,CorC_HlyC,DUF21 CMS1_k127_361616_4 113395.AXAI01000007_gene1396 1.006e-160 513.0 COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,2TRDA@28211|Alphaproteobacteria,3JSY5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) aroB - 2.7.1.71,4.2.3.4 ko:K01735,ko:K13829 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412,R03083 RC00002,RC00078,RC00847 ko00000,ko00001,ko00002,ko01000 - - - DHQ_synthase,SKI CMS1_k127_3618596_11 1245471.PCA10_31160 9.046e-12 70.0 COG3219@1|root,COG3219@2|Bacteria,1QAP4@1224|Proteobacteria,1S0G6@1236|Gammaproteobacteria,1YH3V@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Putative DNA-binding domain - - - - - - - - - - - - DUF2063 CMS1_k127_3618596_1 1297863.APJF01000021_gene170 2.709e-119 394.0 COG3220@1|root,COG3220@2|Bacteria,1MURE@1224|Proteobacteria,2TRZJ@28211|Alphaproteobacteria,3JR0V@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Belongs to the UPF0276 family - - - ko:K09930 - - - - ko00000 - - - DUF692 CMS1_k127_3618596_10 1297863.APJF01000021_gene171 5.057e-35 136.0 COG5572@1|root,COG5572@2|Bacteria,1MZ6Q@1224|Proteobacteria,2UJ9X@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Predicted integral membrane protein (DUF2282) - - - - - - - - - - - - DUF2282 CMS1_k127_3618596_6 420324.KI912063_gene6835 1.291e-62 222.0 COG1595@1|root,COG1595@2|Bacteria,1MVS7@1224|Proteobacteria,2UA8J@28211|Alphaproteobacteria,1JVKM@119045|Methylobacteriaceae 28211|Alphaproteobacteria K Sigma-70 region 2 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 CMS1_k127_3618596_4 420324.KI912063_gene6836 5.374e-73 254.0 COG4944@1|root,COG4944@2|Bacteria,1RD4P@1224|Proteobacteria,2U8EX@28211|Alphaproteobacteria,1JYWQ@119045|Methylobacteriaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF1109) - - - - - - - - - - - - DUF1109 CMS1_k127_3618596_5 365046.Rta_27470 7.524e-71 250.0 COG2128@1|root,COG2128@2|Bacteria,1QKTS@1224|Proteobacteria,2VWVV@28216|Betaproteobacteria,4AIAM@80864|Comamonadaceae 28216|Betaproteobacteria S Carboxymuconolactone decarboxylase family - - - - - - - - - - - - CMD CMS1_k127_3618596_13 319003.Bra1253DRAFT_03906 9.28e-10 64.0 2AEKQ@1|root,314GF@2|Bacteria,1NAA2@1224|Proteobacteria,2UI5N@28211|Alphaproteobacteria,3K15I@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - Cys_rich_CWC CMS1_k127_3618596_3 1429916.X566_23875 5.501e-111 372.0 2CIPC@1|root,2Z9HB@2|Bacteria,1R3W8@1224|Proteobacteria,2TST7@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Glycosyltransferase family 87 - - - - - - - - - - - - GT87 CMS1_k127_3618596_9 1380394.JADL01000001_gene2145 7.944e-36 138.0 COG2329@1|root,COG2329@2|Bacteria,1N078@1224|Proteobacteria,2U99H@28211|Alphaproteobacteria,2JXH5@204441|Rhodospirillales 204441|Rhodospirillales S Antibiotic biosynthesis monooxygenase - - - - - - - - - - - - ABM CMS1_k127_3618596_2 1123024.AUII01000016_gene1270 1.497e-113 377.0 COG0620@1|root,COG0620@2|Bacteria,2H8H4@201174|Actinobacteria 201174|Actinobacteria E Methionine synthase - - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_2 CMS1_k127_3618596_8 318996.AXAZ01000014_gene2901 4.474e-42 158.0 COG3011@1|root,COG3011@2|Bacteria,1N0YV@1224|Proteobacteria,2U5MD@28211|Alphaproteobacteria,3JY5Y@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria CH Protein of unknown function, DUF393 - - - - - - - - - - - - DUF393 CMS1_k127_3618596_0 1038866.KB902782_gene5913 3.77e-129 426.0 COG0702@1|root,COG0702@2|Bacteria,1MZ0C@1224|Proteobacteria,2TSBI@28211|Alphaproteobacteria,3JQMF@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria GM DoxX-like family - - - - - - - - - - - - DoxX_3,Epimerase,NAD_binding_10 CMS1_k127_3618596_7 1121028.ARQE01000001_gene3388 1.535e-59 210.0 COG5528@1|root,COG5528@2|Bacteria,1RDUE@1224|Proteobacteria,2U7HT@28211|Alphaproteobacteria 28211|Alphaproteobacteria S integral membrane protein - - - - - - - - - - - - DUF2269 CMS1_k127_3618596_12 331869.BAL199_02804 3.384e-10 66.0 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria 28211|Alphaproteobacteria T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,PAS_3,PAS_4,Response_reg CMS1_k127_3619844_0 395961.Cyan7425_1241 4.907e-46 179.0 COG0673@1|root,COG0673@2|Bacteria,1G18K@1117|Cyanobacteria,3KGS4@43988|Cyanothece 1117|Cyanobacteria S PFAM oxidoreductase domain protein mviM - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C CMS1_k127_3623751_0 1297569.MESS2_1190033 6.744e-179 563.0 COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,2TRW0@28211|Alphaproteobacteria,43IFQ@69277|Phyllobacteriaceae 28211|Alphaproteobacteria C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type alpha subunit - - 1.2.4.1 ko:K00161,ko:K21416 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh CMS1_k127_3623751_1 1297569.MESS2_1190032 3.671e-174 550.0 COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,2TRFK@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit - - 1.2.4.1 ko:K00162,ko:K21417 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C CMS1_k127_3623751_2 1120983.KB894571_gene2482 1.149e-96 319.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,1JN7Y@119043|Rhodobiaceae 28211|Alphaproteobacteria C Aldehyde dehydrogenase family gabD1 - 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh CMS1_k127_3630872_2 1411123.JQNH01000001_gene1175 1.953e-62 222.0 COG1215@1|root,COG1215@2|Bacteria,1RA75@1224|Proteobacteria,2TXAA@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Glycosyl transferase group 2 family protein - - - - - - - - - - - - Glyco_tranf_2_3,Glycos_transf_2 CMS1_k127_3630872_1 626418.bglu_2p1130 4.831e-97 329.0 COG0639@1|root,COG0639@2|Bacteria,1PXN4@1224|Proteobacteria 1224|Proteobacteria T COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - - - - - - - - - - Metallophos_2 CMS1_k127_3630872_0 1411123.JQNH01000001_gene1174 2.852e-141 462.0 COG0535@1|root,COG0535@2|Bacteria,1MU07@1224|Proteobacteria 1224|Proteobacteria T radical SAM - - - - - - - - - - - - DUF3641,Fer4_12,Radical_SAM CMS1_k127_3630872_3 1187851.A33M_0044 3.962e-37 141.0 28I53@1|root,2Z88I@2|Bacteria,1NE5N@1224|Proteobacteria,2TTBB@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF3750) - - - - - - - - - - - - DUF3750 CMS1_k127_3633436_2 266779.Meso_2237 6.549e-16 78.0 COG2010@1|root,COG2010@2|Bacteria,1N8V1@1224|Proteobacteria,2UG8G@28211|Alphaproteobacteria,43M64@69277|Phyllobacteriaceae 28211|Alphaproteobacteria C cytochrome C - - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 CMS1_k127_3633436_0 1187851.A33M_2467 3.888e-155 498.0 COG1902@1|root,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,2TQPY@28211|Alphaproteobacteria,3FDR1@34008|Rhodovulum 28211|Alphaproteobacteria C NADH:flavin oxidoreductase / NADH oxidase family namA - - - - - - - - - - - Oxidored_FMN CMS1_k127_3633436_1 1120983.KB894571_gene2641 2.933e-77 267.0 COG0697@1|root,COG0697@2|Bacteria,1R46X@1224|Proteobacteria,2TSE9@28211|Alphaproteobacteria,1JNZH@119043|Rhodobiaceae 28211|Alphaproteobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA CMS1_k127_3633436_3 1454004.AW11_02740 0.0005081 44.0 COG3222@1|root,COG3222@2|Bacteria,1RB1V@1224|Proteobacteria,2VRM0@28216|Betaproteobacteria 28216|Betaproteobacteria S Uncharacterized protein conserved in bacteria (DUF2064) - - - ko:K09931 - - - - ko00000 - - - DUF2064 CMS1_k127_3634110_9 652103.Rpdx1_4249 3.785e-47 173.0 COG0859@1|root,COG0859@2|Bacteria,1MYZA@1224|Proteobacteria,2U0ZB@28211|Alphaproteobacteria,3JVZA@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Glycosyltransferase family 9 (heptosyltransferase) waaC - - ko:K02841 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 CMS1_k127_3634110_2 1429916.X566_01805 1.045e-144 466.0 COG1087@1|root,COG1087@2|Bacteria,1MUHI@1224|Proteobacteria,2TTC7@28211|Alphaproteobacteria,3JVFI@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Belongs to the NAD(P)-dependent epimerase dehydratase family galE - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase CMS1_k127_3634110_0 316055.RPE_1447 3.073e-248 785.0 COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2TQMR@28211|Alphaproteobacteria,3JRJ4@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria V ABC transporter MA20_07905 - - ko:K06147,ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran CMS1_k127_3634110_7 1380355.JNIJ01000016_gene5740 7.502e-106 347.0 COG0179@1|root,COG0179@2|Bacteria,1MVFA@1224|Proteobacteria,2TRTM@28211|Alphaproteobacteria,3JR2I@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria Q Fumarylacetoacetate (FAA) hydrolase family MA20_07900 - 3.7.1.20 ko:K16165 ko00350,ko01100,ko01120,map00350,map01100,map01120 - R01085 RC00326,RC00446 ko00000,ko00001,ko01000 - - - FAA_hydrolase CMS1_k127_3634110_4 1187851.A33M_0281 1.645e-110 365.0 COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2TR61@28211|Alphaproteobacteria,3FD1Y@34008|Rhodovulum 28211|Alphaproteobacteria E ATPases associated with a variety of cellular activities - - - ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran CMS1_k127_3634110_8 1187851.A33M_0280 3.513e-104 345.0 COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,2TQVU@28211|Alphaproteobacteria,3FE3S@34008|Rhodovulum 28211|Alphaproteobacteria E Branched-chain amino acid ATP-binding cassette transporter - - - ko:K01995,ko:K01997,ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C,BPD_transp_2 CMS1_k127_3634110_5 1121033.AUCF01000030_gene167 1.216e-108 368.0 COG4177@1|root,COG4177@2|Bacteria,1NE3E@1224|Proteobacteria,2TTWY@28211|Alphaproteobacteria,2JT5A@204441|Rhodospirillales 204441|Rhodospirillales E Branched-chain amino acid transport system / permease component - - - - - - - - - - - - BPD_transp_2 CMS1_k127_3634110_6 1187851.A33M_0278 3.167e-108 358.0 COG0559@1|root,COG0559@2|Bacteria,1N5XH@1224|Proteobacteria,2TSH5@28211|Alphaproteobacteria,3FEM5@34008|Rhodovulum 28211|Alphaproteobacteria U Branched-chain amino acid transport system / permease component - - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 CMS1_k127_3634110_3 1205680.CAKO01000002_gene3007 2.266e-120 402.0 COG0683@1|root,COG0683@2|Bacteria,1MWQB@1224|Proteobacteria,2U16N@28211|Alphaproteobacteria,2JVNK@204441|Rhodospirillales 204441|Rhodospirillales E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - - - - - - - - - - Peripla_BP_6 CMS1_k127_3634110_10 936455.KI421499_gene7014 1.154e-32 134.0 COG1846@1|root,COG1846@2|Bacteria,1N7PQ@1224|Proteobacteria,2UF5S@28211|Alphaproteobacteria,3JRI5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - - - - - - - - - - MarR,MarR_2 CMS1_k127_3634110_1 1144307.PMI04_02905 9.533e-148 478.0 COG0154@1|root,COG0154@2|Bacteria,1MU51@1224|Proteobacteria,2TSYS@28211|Alphaproteobacteria,2K1WY@204457|Sphingomonadales 204457|Sphingomonadales J Amidase - - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase CMS1_k127_3635066_3 1550073.JROH01000027_gene933 2.899e-07 57.0 2AM5R@1|root,31C05@2|Bacteria,1NNC3@1224|Proteobacteria,2UN04@28211|Alphaproteobacteria,2K6VS@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - CMS1_k127_3635066_0 351607.Acel_1041 8.555e-52 194.0 COG0662@1|root,COG0662@2|Bacteria,2GN99@201174|Actinobacteria 201174|Actinobacteria G Cupin domain - - - - - - - - - - - - Cupin_2 CMS1_k127_3635066_1 450851.PHZ_p0116 2.487e-26 111.0 COG0789@1|root,COG0789@2|Bacteria,1N831@1224|Proteobacteria,2UFMB@28211|Alphaproteobacteria 28211|Alphaproteobacteria K MerR HTH family regulatory protein - - - ko:K18997 - - - - ko00000,ko03036 - - - MerR_2 CMS1_k127_3635066_2 648757.Rvan_1941 1.316e-07 53.0 COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,2TR01@28211|Alphaproteobacteria,3N87N@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria O DnaJ C terminal domain - - - - - - - - - - - - DnaJ,DnaJ_C CMS1_k127_3641191_0 1207063.P24_08439 1.398e-214 680.0 COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,2TQZ6@28211|Alphaproteobacteria,2JREA@204441|Rhodospirillales 204441|Rhodospirillales EQ Hydantoinase/oxoprolinase N-terminal region - - - - - - - - - - - - Hydant_A_N,Hydantoinase_A CMS1_k127_3645876_0 85643.Tmz1t_2959 5.9e-304 943.0 COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,2VMWP@28216|Betaproteobacteria,2KVYZ@206389|Rhodocyclales 206389|Rhodocyclales C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - 1.17.5.1,3.1.2.25 ko:K18361 ko00360,map00360 - R07222,R07294 RC00004,RC01844,RC01903 ko00000,ko00001,ko01000 - - - Molybdopterin,Molydop_binding CMS1_k127_3645876_11 62928.azo1947 1.353e-91 323.0 COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,2VKVM@28216|Betaproteobacteria,2KXUS@206389|Rhodocyclales 206389|Rhodocyclales C 4Fe-4S binding domain - - - ko:K18362 ko00360,map00360 - R07222,R07294 RC00004,RC01844,RC01903 ko00000,ko00001 - - - - CMS1_k127_3645876_13 748247.AZKH_2902 1.596e-47 192.0 COG3302@1|root,COG3302@2|Bacteria,1R64Q@1224|Proteobacteria,2VNSS@28216|Betaproteobacteria,2KVPW@206389|Rhodocyclales 206389|Rhodocyclales S DMSO reductase anchor subunit (DmsC) padD - - ko:K18363 ko00360,map00360 - R07222,R07294 RC00004,RC01844,RC01903 ko00000,ko00001 - - - DmsC CMS1_k127_3645876_3 316055.RPE_0981 1.532e-222 698.0 COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,2TRVF@28211|Alphaproteobacteria,3K64X@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - 6.2.1.30 ko:K01912 ko00360,ko01120,ko05111,map00360,map01120,map05111 - R02539 RC00004,RC00014 ko00000,ko00001,ko01000 - - - AMP-binding,AMP-binding_C_2 CMS1_k127_3645876_16 1121033.AUCF01000020_gene670 3.864e-33 134.0 COG1633@1|root,COG1633@2|Bacteria,1RJFW@1224|Proteobacteria,2U6JY@28211|Alphaproteobacteria,2JTDY@204441|Rhodospirillales 204441|Rhodospirillales S Rubrerythrin - - - - - - - - - - - - Rubrerythrin CMS1_k127_3645876_8 316055.RPE_0601 8.934e-129 416.0 COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,2TR4R@28211|Alphaproteobacteria,3JTAE@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Thiamine pyrophosphate enzyme, C-terminal TPP binding domain MA20_01040 - 1.2.7.11,1.2.7.3 ko:K00175 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - PFO_beta_C,TPP_enzyme_C CMS1_k127_3645876_4 1316936.K678_14799 3.092e-212 673.0 COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,2TU21@28211|Alphaproteobacteria,2JRK3@204441|Rhodospirillales 204441|Rhodospirillales C Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg - - 1.2.7.11,1.2.7.3 ko:K00174 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - PFOR_II,POR,POR_N,Transketolase_C CMS1_k127_3645876_7 85643.Tmz1t_2954 6.038e-157 503.0 COG1064@1|root,COG1064@2|Bacteria,1QVIH@1224|Proteobacteria,2VP5E@28216|Betaproteobacteria,2KVHQ@206389|Rhodocyclales 28216|Betaproteobacteria C Zinc-binding dehydrogenase - - 1.1.1.368 ko:K07538 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00541 R05581 RC00850 ko00000,ko00001,ko00002,ko01000 - - - ADH_N,ADH_zinc_N CMS1_k127_3645876_6 1187851.A33M_3194 1.582e-185 586.0 COG1024@1|root,COG1024@2|Bacteria,1QY95@1224|Proteobacteria,2U4PY@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Enoyl-CoA hydratase/isomerase - - 3.7.1.21 ko:K07539 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00541 R05593,R05594,R10696 RC01430,RC01431,RC03237 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 CMS1_k127_3645876_10 1232410.KI421412_gene165 2.891e-104 346.0 COG1024@1|root,COG1024@2|Bacteria,1R8QP@1224|Proteobacteria,42S3Y@68525|delta/epsilon subdivisions,2WNXJ@28221|Deltaproteobacteria,43UFV@69541|Desulfuromonadales 28221|Deltaproteobacteria I Enoyl-CoA hydratase/isomerase bamR - 4.2.1.100 ko:K07537 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00541 R05597 RC03168 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 CMS1_k127_3645876_5 85643.Tmz1t_2951 1.432e-185 587.0 COG1775@1|root,COG1775@2|Bacteria,1NNW9@1224|Proteobacteria,2VV78@28216|Betaproteobacteria,2KXPH@206389|Rhodocyclales 206389|Rhodocyclales E 2-hydroxyglutaryl-CoA dehydratase, D-component - - 1.3.7.8 ko:K04112 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00541 R02451 RC00002,RC01839 ko00000,ko00001,ko00002,ko01000 - - - HGD-D CMS1_k127_3645876_1 652103.Rpdx1_4128 2.004e-245 763.0 COG1775@1|root,COG1775@2|Bacteria,1NKED@1224|Proteobacteria,2U31W@28211|Alphaproteobacteria 28211|Alphaproteobacteria E benzoyl-CoA reductase - - 1.3.7.8 ko:K04113 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00541 R02451 RC00002,RC01839 ko00000,ko00001,ko00002,ko01000 - - - HGD-D CMS1_k127_3645876_2 316055.RPE_0606 5.421e-231 721.0 COG1924@1|root,COG1924@2|Bacteria,1R411@1224|Proteobacteria,2U1DN@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Benzoyl-CoA reductase subunit - - 1.3.7.8 ko:K04114 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00541 R02451 RC00002,RC01839 ko00000,ko00001,ko00002,ko01000 - - - BcrAD_BadFG CMS1_k127_3645876_9 85643.Tmz1t_2948 6.492e-123 402.0 COG1924@1|root,COG1924@2|Bacteria,1R6HU@1224|Proteobacteria,2VSQQ@28216|Betaproteobacteria,2KXX8@206389|Rhodocyclales 206389|Rhodocyclales I BadF/BadG/BcrA/BcrD ATPase family - - 1.3.7.8 ko:K04115 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00541 R02451 RC00002,RC01839 ko00000,ko00001,ko00002,ko01000 - - - BcrAD_BadFG CMS1_k127_3645876_15 258594.RPA0662 1.683e-36 139.0 COG1145@1|root,COG1145@2|Bacteria,1MZ6H@1224|Proteobacteria,2UG0Z@28211|Alphaproteobacteria 28211|Alphaproteobacteria C ferredoxin - - - - - - - - - - - - Fer4 CMS1_k127_3645876_12 652103.Rpdx1_3434 8.171e-48 179.0 2E0AX@1|root,32VY8@2|Bacteria,1N21Q@1224|Proteobacteria,2UECC@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Hemerythrin HHE cation binding domain - - - - - - - - - - - - Hemerythrin CMS1_k127_3645876_17 1244869.H261_10407 3.293e-27 120.0 COG0454@1|root,COG0456@2|Bacteria,1RGZ2@1224|Proteobacteria 1224|Proteobacteria K Acetyltransferase (GNAT) family - - - - - - - - - - - - Acetyltransf_1 CMS1_k127_3645876_14 85643.Tmz1t_2945 6.778e-47 177.0 COG0454@1|root,COG0456@2|Bacteria,1RGZ2@1224|Proteobacteria,2VXB4@28216|Betaproteobacteria,2KXES@206389|Rhodocyclales 206389|Rhodocyclales K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 CMS1_k127_3645876_18 1244869.H261_15767 3.285e-15 78.0 COG3278@1|root,COG3278@2|Bacteria,1PU2D@1224|Proteobacteria,2U5ID@28211|Alphaproteobacteria,2JS12@204441|Rhodospirillales 204441|Rhodospirillales O Belongs to the heme-copper respiratory oxidase family - - - - - - - - - - - - - CMS1_k127_3653575_0 1187851.A33M_4201 7.501e-198 626.0 COG1657@1|root,COG1657@2|Bacteria,1MUIP@1224|Proteobacteria,2TRF3@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Squalene--hopene cyclase shc - 4.2.1.129,5.4.99.17 ko:K06045 ko00909,ko01110,map00909,map01110 - R07322,R07323 RC01850,RC01851 ko00000,ko00001,ko01000 - - - SQHop_cyclase_C,SQHop_cyclase_N CMS1_k127_3653575_1 652103.Rpdx1_1604 1.654e-57 203.0 COG1232@1|root,COG1232@2|Bacteria,1NQUH@1224|Proteobacteria,2TTH7@28211|Alphaproteobacteria,3K6M8@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H Flavin containing amine oxidoreductase hpnE - 1.17.8.1 ko:K21677 - - - - ko00000,ko01000 - - - Amino_oxidase CMS1_k127_3660230_1 936455.KI421499_gene1283 4.869e-102 336.0 COG2063@1|root,COG2063@2|Bacteria,1RDEY@1224|Proteobacteria,2TRHN@28211|Alphaproteobacteria,3JQVQ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria N Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation flgH - - ko:K02393 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlgH CMS1_k127_3660230_2 78245.Xaut_4637 3.884e-67 231.0 COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,2U74V@28211|Alphaproteobacteria,3EZ9C@335928|Xanthobacteraceae 28211|Alphaproteobacteria K Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters dksA - - ko:K06204 ko02026,map02026 - - - ko00000,ko00001,ko03000,ko03009,ko03021 - - - zf-dskA_traR CMS1_k127_3660230_3 1297863.APJF01000024_gene1731 7.781e-37 147.0 2E5SK@1|root,330GZ@2|Bacteria,1N7R1@1224|Proteobacteria,2UFAX@28211|Alphaproteobacteria,3JY0K@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria N Class II flagellar assembly regulator fliX GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - FliX CMS1_k127_3660230_0 1429916.X566_24605 4.569e-179 568.0 COG1706@1|root,COG1706@2|Bacteria,1MVKW@1224|Proteobacteria,2TQNX@28211|Alphaproteobacteria,3JTS6@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria N Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation flgI GO:0005575,GO:0005623,GO:0009288,GO:0009425,GO:0042597,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464 - ko:K02394 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FlgI CMS1_k127_3660230_5 883080.HMPREF9697_00077 6.397e-22 105.0 COG3951@1|root,COG3951@2|Bacteria,1N7K5@1224|Proteobacteria,2UFY2@28211|Alphaproteobacteria,3JZX3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria MNO Rod binding protein cheL - - - - - - - - - - - Rod-binding CMS1_k127_3660230_4 316055.RPE_1529 1.303e-27 118.0 2BW5Z@1|root,32QZ3@2|Bacteria,1RDZK@1224|Proteobacteria,2UD61@28211|Alphaproteobacteria,3JYRH@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_3660230_6 990285.RGCCGE502_00120 6.612e-12 71.0 COG0438@1|root,COG0438@2|Bacteria,1REXS@1224|Proteobacteria,2UAS6@28211|Alphaproteobacteria,4BJ70@82115|Rhizobiaceae 28211|Alphaproteobacteria M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glycos_transf_1 CMS1_k127_3662810_7 411684.HPDFL43_19022 2.646e-11 71.0 COG1376@1|root,COG1376@2|Bacteria,1MVYT@1224|Proteobacteria,2U055@28211|Alphaproteobacteria,43QZA@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S L,D-transpeptidase catalytic domain - - - - - - - - - - - - YkuD CMS1_k127_3662810_1 1449065.JMLL01000011_gene2616 9.401e-86 290.0 COG0508@1|root,COG0508@2|Bacteria,1NBIZ@1224|Proteobacteria,2TR2F@28211|Alphaproteobacteria,43NXX@69277|Phyllobacteriaceae 28211|Alphaproteobacteria C dehydrogenase complex catalyzes the overall conversion of - - - - - - - - - - - - - CMS1_k127_3662810_3 1038858.AXBA01000002_gene3943 1.369e-60 214.0 COG2020@1|root,COG2020@2|Bacteria,1RECR@1224|Proteobacteria,2U6MH@28211|Alphaproteobacteria,3EZ8Z@335928|Xanthobacteraceae 28211|Alphaproteobacteria O Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - - - - - - - - - - ICMT,PEMT CMS1_k127_3662810_4 1126627.BAWE01000002_gene1214 4.675e-60 213.0 COG1376@1|root,COG1376@2|Bacteria,1MVYT@1224|Proteobacteria,2U7F8@28211|Alphaproteobacteria,3JTDU@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S L,D-transpeptidase catalytic domain MA20_25100 - - - - - - - - - - - YkuD CMS1_k127_3662810_5 266779.Meso_3519 4.223e-41 164.0 2B9G4@1|root,322U3@2|Bacteria,1P0JW@1224|Proteobacteria,2UEFE@28211|Alphaproteobacteria,43PCH@69277|Phyllobacteriaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_3662810_0 864069.MicloDRAFT_00056030 7.433e-246 777.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2TS8E@28211|Alphaproteobacteria,1JSMW@119045|Methylobacteriaceae 28211|Alphaproteobacteria I PFAM Enoyl-CoA hydratase isomerase - - 1.1.1.35 ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 M00087 R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000 - - - 3HCDH,3HCDH_N,ECH_1 CMS1_k127_3662810_2 392499.Swit_4246 2e-77 268.0 COG0235@1|root,COG0235@2|Bacteria,1MWP9@1224|Proteobacteria,2TRMV@28211|Alphaproteobacteria,2K8Y9@204457|Sphingomonadales 204457|Sphingomonadales G Class II Aldolase and Adducin N-terminal domain - - - - - - - - - - - - Aldolase_II CMS1_k127_3662810_6 1038862.KB893805_gene4087 5.001e-29 124.0 COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,2TRZE@28211|Alphaproteobacteria,3JRN3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP CMS1_k127_3663087_3 113395.AXAI01000002_gene5132 2.446e-29 118.0 COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,2TSCJ@28211|Alphaproteobacteria,3JSNP@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) leuA - 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 - - - HMGL-like,LeuA_dimer CMS1_k127_3663087_5 666684.AfiDRAFT_2927 3.436e-06 55.0 2AJI9@1|root,31A4Y@2|Bacteria,1NVJ4@1224|Proteobacteria,2US8T@28211|Alphaproteobacteria,3K45W@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_3663087_0 396588.Tgr7_1471 1.625e-253 798.0 COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,1RMH7@1236|Gammaproteobacteria 1236|Gammaproteobacteria S TRAP transporter, 4TM 12TM fusion protein - - - - - - - - - - - - DctM CMS1_k127_3663087_1 396588.Tgr7_1470 2.989e-112 372.0 COG2358@1|root,COG2358@2|Bacteria 2|Bacteria G TRAP transporter, solute receptor (TAXI family MA20_27285 - - ko:K07080 - - - - ko00000 - - - NMT1_3 CMS1_k127_3663087_2 316057.RPD_2116 4.528e-33 134.0 2EAB6@1|root,334FE@2|Bacteria,1R4B5@1224|Proteobacteria,2U21J@28211|Alphaproteobacteria,3JWR9@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S LTXXQ motif family protein - - - ko:K07803 ko02020,map02020 - - - ko00000,ko00001,ko03110 - - - LTXXQ CMS1_k127_3663087_4 1187851.A33M_3824 2.876e-25 111.0 2E560@1|root,32ZYT@2|Bacteria,1RAE3@1224|Proteobacteria,2U5G6@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - MA20_01460 - - - - - - - - - - - - CMS1_k127_3670043_4 631454.N177_1885 7.381e-77 271.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VFM7@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC CMS1_k127_3670043_3 631454.N177_1887 1.31e-132 439.0 COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TR4Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein conserved in bacteria - - - ko:K07793 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctA CMS1_k127_3670043_1 1125973.JNLC01000011_gene592 1.276e-181 574.0 COG0673@1|root,COG0673@2|Bacteria,1QSNV@1224|Proteobacteria,2TUMB@28211|Alphaproteobacteria 28211|Alphaproteobacteria S oxidoreductase - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C CMS1_k127_3670043_6 1150469.RSPPHO_01282 2.916e-12 71.0 2EQH0@1|root,33I30@2|Bacteria,1NJ7T@1224|Proteobacteria,2UKW8@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_3670043_2 1123060.JONP01000001_gene1519 6.639e-137 441.0 COG0235@1|root,COG0235@2|Bacteria,1MWP9@1224|Proteobacteria,2TRMV@28211|Alphaproteobacteria,2JRJV@204441|Rhodospirillales 204441|Rhodospirillales G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases - - - - - - - - - - - - Aldolase_II CMS1_k127_3670043_0 323098.Nwi_0756 8.496e-182 575.0 COG0523@1|root,COG0523@2|Bacteria,1MVZV@1224|Proteobacteria,2TS4B@28211|Alphaproteobacteria,3JSTE@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S cobalamin synthesis protein - - - - - - - - - - - - CobW_C,cobW CMS1_k127_3670043_5 318996.AXAZ01000022_gene574 4.646e-34 134.0 COG1376@1|root,COG1376@2|Bacteria,1MVYT@1224|Proteobacteria,2U60K@28211|Alphaproteobacteria,3JT37@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S L,D-transpeptidase catalytic domain - - - - - - - - - - - - YkuD CMS1_k127_3717261_4 639283.Snov_1691 2.708e-65 227.0 COG1763@1|root,COG1763@2|Bacteria,1RD3Q@1224|Proteobacteria,2U5T0@28211|Alphaproteobacteria,3F09F@335928|Xanthobacteraceae 28211|Alphaproteobacteria H Molybdopterin guanine dinucleotide synthesis protein B mobB GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03753 - - - - ko00000 - - - MobB CMS1_k127_3717261_0 1101191.KI912577_gene1935 4.495e-151 489.0 COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,2TQRI@28211|Alphaproteobacteria,1JTF1@119045|Methylobacteriaceae 28211|Alphaproteobacteria H MoeA domain protein domain I and II moeA - 2.10.1.1 ko:K03750 ko00790,ko01100,map00790,map01100 - R09735 RC03462 ko00000,ko00001,ko01000 - - - MoCF_biosynth,MoeA_C,MoeA_N CMS1_k127_3717261_5 1038867.AXAY01000038_gene739 7.437e-05 47.0 2AHJS@1|root,317XI@2|Bacteria,1NM4X@1224|Proteobacteria,2UJPX@28211|Alphaproteobacteria,3K1TS@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_3717261_3 1304877.KI519399_gene3476 1.696e-72 252.0 COG0746@1|root,COG0746@2|Bacteria,1RH3M@1224|Proteobacteria,2TV2G@28211|Alphaproteobacteria,3JT8E@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor mobA - 2.7.7.77 ko:K03752 ko00790,ko01100,map00790,map01100 - R11581 - ko00000,ko00001,ko01000 - - - NTP_transf_3 CMS1_k127_3717261_1 1411123.JQNH01000001_gene2290 1.403e-145 466.0 COG1526@1|root,COG1526@2|Bacteria,1MY28@1224|Proteobacteria,2VFYH@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH fdhD - - ko:K02379 - - - - ko00000 - - - FdhD-NarQ CMS1_k127_3717261_2 1254432.SCE1572_16030 3.606e-118 392.0 COG0620@1|root,COG0620@2|Bacteria,1MV2Z@1224|Proteobacteria,42NPA@68525|delta/epsilon subdivisions,2WT46@28221|Deltaproteobacteria 28221|Deltaproteobacteria E Cobalamin-independent synthase, Catalytic domain - - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_2 CMS1_k127_3722003_0 323098.Nwi_3077 4.733e-193 614.0 COG4191@1|root,COG4191@2|Bacteria,1MVK7@1224|Proteobacteria,2TR44@28211|Alphaproteobacteria,3JU63@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T His Kinase A (phosphoacceptor) domain regM - - - - - - - - - - - HATPase_c,HisKA CMS1_k127_3722003_1 391937.NA2_02609 3.94e-175 561.0 COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2TU0K@28211|Alphaproteobacteria,43HE3@69277|Phyllobacteriaceae 28211|Alphaproteobacteria C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family merA - - - - - - - - - - - Pyr_redox_2,Pyr_redox_dim CMS1_k127_3722003_2 1120792.JAFV01000001_gene3199 6.985e-61 220.0 COG0398@1|root,COG0398@2|Bacteria,1MVF3@1224|Proteobacteria,2U6DE@28211|Alphaproteobacteria,370E1@31993|Methylocystaceae 28211|Alphaproteobacteria S SNARE associated Golgi protein merA_1 - - - - - - - - - - - SNARE_assoc CMS1_k127_3722003_5 323098.Nwi_3076 5.579e-16 79.0 COG0230@1|root,COG0230@2|Bacteria,1NGGS@1224|Proteobacteria,2UJCE@28211|Alphaproteobacteria,3K10Q@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Belongs to the bacterial ribosomal protein bL34 family rpmH - - ko:K02914 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L34 CMS1_k127_3722003_3 1187851.A33M_1040 3.847e-39 151.0 COG0594@1|root,COG0594@2|Bacteria,1N6QY@1224|Proteobacteria,2UFAB@28211|Alphaproteobacteria,3FDI6@34008|Rhodovulum 28211|Alphaproteobacteria J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme rnpA - 3.1.26.5 ko:K03536 - - - - ko00000,ko01000,ko03016 - - - Ribonuclease_P CMS1_k127_3722003_4 1038860.AXAP01000061_gene2373 1.153e-17 88.0 COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,2TSTJ@28211|Alphaproteobacteria,3JQU3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins yidC GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032940,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP,YidC_periplas CMS1_k127_3732937_19 883078.HMPREF9695_02892 5.612e-103 339.0 COG1024@1|root,COG1024@2|Bacteria,1MXBB@1224|Proteobacteria,2TU4V@28211|Alphaproteobacteria,3JRS0@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Belongs to the enoyl-CoA hydratase isomerase family - - 4.1.1.41,4.2.1.17 ko:K01692,ko:K11264 ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212 M00032,M00087 R00923,R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093 RC00097,RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 CMS1_k127_3732937_11 224911.27354307 1.172e-189 600.0 COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TR7Q@28211|Alphaproteobacteria,3JT4Z@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C CoA-transferase family III MA20_43260 - - - - - - - - - - - CoA_transf_3 CMS1_k127_3732937_17 631454.N177_1314 3.949e-152 493.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2TR6Q@28211|Alphaproteobacteria,1JNCZ@119043|Rhodobiaceae 28211|Alphaproteobacteria L DEAD-like helicases superfamily rhlE - 3.6.4.13 ko:K11927 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DEAD,Helicase_C CMS1_k127_3732937_29 631454.N177_1313 1.702e-35 142.0 COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,2UBRU@28211|Alphaproteobacteria,1JPAA@119043|Rhodobiaceae 28211|Alphaproteobacteria J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex infA GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - ko:K02518 - - - - ko00000,ko03012 - - - eIF-1a CMS1_k127_3732937_27 1122603.ATVI01000005_gene3042 2.986e-41 164.0 COG0668@1|root,COG0668@2|Bacteria,1N4UN@1224|Proteobacteria,1T9TX@1236|Gammaproteobacteria,1XBUR@135614|Xanthomonadales 135614|Xanthomonadales M Conserved TM helix - - - - - - - - - - - - MS_channel,TM_helix CMS1_k127_3732937_31 1415778.JQMM01000001_gene1964 2.414e-33 139.0 COG2239@1|root,COG2239@2|Bacteria,1NNAQ@1224|Proteobacteria,1SHM4@1236|Gammaproteobacteria 1236|Gammaproteobacteria P MgtE intracellular N domain - - - - - - - - - - - - CBS,MgtE_N CMS1_k127_3732937_18 1415778.JQMM01000001_gene1963 3.78e-141 462.0 COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,1RNE4@1236|Gammaproteobacteria,1J4XQ@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria P Acts as a magnesium transporter mgtE - - ko:K06213 - - - - ko00000,ko02000 1.A.26.1 - - CBS,MgtE,MgtE_N CMS1_k127_3732937_15 1041142.ATTP01000016_gene2739 1.792e-165 556.0 COG2939@1|root,COG2939@2|Bacteria,1MW05@1224|Proteobacteria,2TS7R@28211|Alphaproteobacteria,4BBYF@82115|Rhizobiaceae 28211|Alphaproteobacteria E carboxypeptidase MA20_31445 - - - - - - - - - - - Peptidase_S10 CMS1_k127_3732937_4 1038859.AXAU01000002_gene332 0.0 1097.0 COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2TSTW@28211|Alphaproteobacteria,3JW5G@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria EH Thiamine pyrophosphate enzyme, central domain ilvB - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N CMS1_k127_3732937_6 1125973.JNLC01000012_gene948 0.0 1034.0 COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,2TRER@28211|Alphaproteobacteria,3JR6I@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties glgP GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 - Phosphorylase CMS1_k127_3732937_16 504832.OCAR_7061 4.424e-163 532.0 COG1640@1|root,COG1640@2|Bacteria,1QTVJ@1224|Proteobacteria,2TW4K@28211|Alphaproteobacteria,3JR1W@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G 4-alpha-glucanotransferase malQ - 2.4.1.25,5.4.99.15 ko:K00705,ko:K06044 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R01824,R05196,R09995 RC00049 ko00000,ko00001,ko00002,ko01000 - GH13,GH77 - Alpha-amylase,Glyco_hydro_77 CMS1_k127_3732937_7 1038860.AXAP01000044_gene7641 7.485e-295 917.0 COG0366@1|root,COG0366@2|Bacteria,1MWBZ@1224|Proteobacteria,2TVJ1@28211|Alphaproteobacteria,3JTJN@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB glgE - 2.4.99.16 ko:K16147 ko00500,ko01100,map00500,map01100 - R09994 - ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,DUF3416,Malt_amylase_C CMS1_k127_3732937_0 316056.RPC_3679 0.0 1474.0 COG0366@1|root,COG3281@1|root,COG0366@2|Bacteria,COG3281@2|Bacteria,1MVKX@1224|Proteobacteria,2TRS3@28211|Alphaproteobacteria,3JT1J@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G Maltogenic Amylase, C-terminal domain treS - 3.2.1.1,5.4.99.16 ko:K05343 ko00500,ko01100,map00500,map01100 - R01557,R02108,R02112,R11262 RC01816 ko00000,ko00001,ko01000 - GH13 - APH,Alpha-amylase,Malt_amylase_C CMS1_k127_3732937_2 189753.AXAS01000025_gene398 0.0 1164.0 COG0296@1|root,COG0296@2|Bacteria,1QTVN@1224|Proteobacteria,2TR5K@28211|Alphaproteobacteria,3JUN5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position glgB - 2.4.1.18 ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 - ko00000,ko00001,ko00002,ko01000,ko04147 - CBM48,GH13 - Alpha-amylase,Alpha-amylase_C,CBM_48 CMS1_k127_3732937_8 1150626.PHAMO_230004 7.33e-257 811.0 COG1523@1|root,COG1523@2|Bacteria,1MU19@1224|Proteobacteria,2TRVS@28211|Alphaproteobacteria,2JQKB@204441|Rhodospirillales 204441|Rhodospirillales G Belongs to the glycosyl hydrolase 13 family glgX - 3.2.1.68 ko:K01214 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R09995,R11261 - ko00000,ko00001,ko00002,ko01000 - CBM48,GH13 - Alpha-amylase,CBM_48 CMS1_k127_3732937_10 316058.RPB_1880 1.091e-229 728.0 COG0296@1|root,COG0296@2|Bacteria,1MVM7@1224|Proteobacteria,2TQUJ@28211|Alphaproteobacteria,3JUR0@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G 4-alpha-D-((1- 4)-alpha-D-glucano)trehalose trehalohydrolase treZ - 2.4.1.18,3.2.1.141 ko:K00700,ko:K01236 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110,R09995,R11256 RC00049 ko00000,ko00001,ko00002,ko01000,ko04147 - CBM48,GH13 - Alpha-amylase,CBM_48,DUF3459 CMS1_k127_3732937_3 172088.AUGA01000004_gene4126 0.0 1098.0 COG3280@1|root,COG3280@2|Bacteria,1QTVK@1224|Proteobacteria,2TW4J@28211|Alphaproteobacteria,3JS6B@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G Alpha amylase, catalytic domain treY - 5.4.99.15 ko:K06044 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R01824,R09995 - ko00000,ko00001,ko00002,ko01000 - GH13 - Alpha-amylase CMS1_k127_3732937_13 316055.RPE_4553 4.554e-172 554.0 COG0380@1|root,COG0380@2|Bacteria,1MUIY@1224|Proteobacteria,2TQMP@28211|Alphaproteobacteria,3JUU9@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor otsA - 2.4.1.15,2.4.1.347 ko:K00697 ko00500,ko01100,map00500,map01100 - R02737 RC00005,RC00049,RC02748 ko00000,ko00001,ko01000,ko01003 - GT20 - Glyco_transf_20 CMS1_k127_3732937_22 991905.SL003B_2535 1.93e-71 255.0 COG1082@1|root,COG1082@2|Bacteria,1N0QZ@1224|Proteobacteria,2UDUZ@28211|Alphaproteobacteria,4BSD5@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria G Xylose isomerase-like TIM barrel - - 3.1.21.2 ko:K01151 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - AP_endonuc_2 CMS1_k127_3732937_26 189753.AXAS01000004_gene996 5.819e-60 215.0 COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,2TT42@28211|Alphaproteobacteria,3JUY5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K helix_turn_helix, cAMP Regulatory protein MA20_38050 - - ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 - - - ko00000,ko00001,ko03000 - - - HTH_Crp_2,cNMP_binding CMS1_k127_3732937_21 1429046.RR21198_2552 2.017e-75 267.0 COG1752@1|root,COG1752@2|Bacteria,2IDUX@201174|Actinobacteria 201174|Actinobacteria S Patatin-like phospholipase - - - ko:K07001 - - - - ko00000 - - - Patatin CMS1_k127_3732937_5 319003.Bra1253DRAFT_00133 0.0 1041.0 COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2TQVN@28211|Alphaproteobacteria,3JTQ7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Adenylate and Guanylate cyclase catalytic domain - - - - - - - - - - - - AAA_16,DZR,Guanylate_cyc,SAM_1 CMS1_k127_3732937_1 378806.STAUR_4016 0.0 1257.0 COG1020@1|root,COG1028@1|root,COG3321@1|root,COG1020@2|Bacteria,COG1028@2|Bacteria,COG3321@2|Bacteria,1QK4F@1224|Proteobacteria,43C79@68525|delta/epsilon subdivisions,2X7HI@28221|Deltaproteobacteria,2YXR8@29|Myxococcales 28221|Deltaproteobacteria Q Pfam:NRPS - - - ko:K16395 ko01052,map01052 - - - ko00000,ko00001 - - - AMP-binding,AMP-binding_C,Acyl_transf_1,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Nitroreductase,PP-binding,PS-DH,ketoacyl-synt CMS1_k127_3732937_24 1167006.UWK_03221 1.525e-64 237.0 COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,42PQZ@68525|delta/epsilon subdivisions,2WMD9@28221|Deltaproteobacteria,2MNAP@213118|Desulfobacterales 28221|Deltaproteobacteria Q Hemolysin-type calcium-binding - - - - - - - - - - - - Cadherin_3,HCBP_related,He_PIG,HemolysinCabind,Peptidase_M91,VWA_2 CMS1_k127_3732937_20 1123060.JONP01000009_gene2108 3.336e-94 320.0 COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,2TSKF@28211|Alphaproteobacteria,2JRWE@204441|Rhodospirillales 28211|Alphaproteobacteria H Pyridoxal phosphate biosynthetic protein PdxA pdxA - 1.1.1.262 ko:K00097 ko00750,ko01100,map00750,map01100 M00124 R05681,R05837,R07406 RC00089,RC00675,RC01475 ko00000,ko00001,ko00002,ko01000 - - - PdxA CMS1_k127_3732937_28 443152.MDG893_15160 7.225e-39 147.0 COG2146@1|root,COG2146@2|Bacteria,1N8PE@1224|Proteobacteria 1224|Proteobacteria P COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases - - - ko:K05710,ko:K14750,ko:K15752 ko00360,ko00621,ko00642,ko01100,ko01120,ko01220,map00360,map00621,map00642,map01100,map01120,map01220 M00544,M00545 R05414,R05440,R06782,R06783,R09512 RC00098,RC01370 br01602,ko00000,ko00001,ko00002 - - - Rieske CMS1_k127_3732937_9 1500257.JQNM01000014_gene2919 3.151e-231 721.0 COG4638@1|root,COG4638@2|Bacteria,1MX47@1224|Proteobacteria,2TV03@28211|Alphaproteobacteria,4B9MF@82115|Rhizobiaceae 28211|Alphaproteobacteria P Rieske [2Fe-2S] domain - - - - - - - - - - - - Rieske CMS1_k127_3732937_30 492774.JQMB01000002_gene773 9.745e-34 137.0 2AAE0@1|root,30ZQ8@2|Bacteria,1PMNU@1224|Proteobacteria,2V08Z@28211|Alphaproteobacteria,4BJFF@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_3732937_14 631454.N177_1694 8.885e-171 558.0 COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TVI3@28211|Alphaproteobacteria,1JN67@119043|Rhodobiaceae 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter TctA family - - - - - - - - - - - - TctA CMS1_k127_3732937_25 443152.MDG893_15327 5.074e-64 233.0 COG3181@1|root,COG3181@2|Bacteria 2|Bacteria E Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC CMS1_k127_3732937_12 1437425.CSEC_1391 2.869e-180 580.0 COG3119@1|root,COG3119@2|Bacteria 2|Bacteria P arylsulfatase activity - - - - - - - - - - - - DUF4976,Sulfatase CMS1_k127_3732937_23 1382306.JNIM01000001_gene1871 1.154e-64 235.0 COG2897@1|root,COG2897@2|Bacteria,2G8GM@200795|Chloroflexi 200795|Chloroflexi P Rhodanese Homology Domain - - - - - - - - - - - - Rhodanese CMS1_k127_3734202_48 1510531.JQJJ01000009_gene504 2.439e-07 53.0 COG4166@1|root,COG4166@2|Bacteria,1MUVU@1224|Proteobacteria,2TQJX@28211|Alphaproteobacteria,3JTJ1@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Bacterial extracellular solute-binding proteins, family 5 Middle yejA - - ko:K13893 ko02010,map02010 M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.21,3.A.1.5.24 - - SBP_bac_5 CMS1_k127_3734202_3 323098.Nwi_0288 5.719e-308 953.0 COG4166@1|root,COG4166@2|Bacteria,1MUVU@1224|Proteobacteria,2TQJX@28211|Alphaproteobacteria,3JTQZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Bacterial extracellular solute-binding proteins, family 5 Middle MA20_18500 - - ko:K02035,ko:K13893 ko02010,ko02024,map02010,map02024 M00239,M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.21,3.A.1.5.24 - - SBP_bac_5 CMS1_k127_3734202_29 1187851.A33M_3460 1.468e-64 229.0 COG3474@1|root,COG3474@2|Bacteria,1RIDN@1224|Proteobacteria,2U142@28211|Alphaproteobacteria,3FDCC@34008|Rhodovulum 28211|Alphaproteobacteria C Cytochrome c cyc - - ko:K08738 ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.6 - - Cytochrom_C CMS1_k127_3734202_26 1211115.ALIQ01000034_gene2018 2.833e-97 323.0 COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,2TUQM@28211|Alphaproteobacteria,3NC10@45404|Beijerinckiaceae 28211|Alphaproteobacteria M Cytidylyltransferase kdsB - 2.7.7.38 ko:K00979 ko00540,ko01100,map00540,map01100 M00063 R03351,R11396 RC00152,RC00910 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CTP_transf_3 CMS1_k127_3734202_18 639283.Snov_0250 7.717e-139 447.0 COG0077@1|root,COG0077@2|Bacteria,1MU60@1224|Proteobacteria,2TSUT@28211|Alphaproteobacteria,3EYVX@335928|Xanthobacteraceae 28211|Alphaproteobacteria E Prephenate dehydratase pheA - 4.2.1.51 ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024 R00691,R01373 RC00360 ko00000,ko00001,ko00002,ko01000 - - - PDT CMS1_k127_3734202_47 504832.OCAR_7057 2.81e-13 73.0 2A8W6@1|root,30XZI@2|Bacteria,1RHFY@1224|Proteobacteria,2U9DG@28211|Alphaproteobacteria,3JZF7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_3734202_22 883078.HMPREF9695_00119 1.662e-121 394.0 COG1028@1|root,COG1028@2|Bacteria,1MXVZ@1224|Proteobacteria,2TSQ4@28211|Alphaproteobacteria,3JQZU@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria IQ Enoyl-(Acyl carrier protein) reductase - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 CMS1_k127_3734202_17 1297865.APJD01000011_gene6524 3.719e-140 455.0 COG0654@1|root,COG0654@2|Bacteria,1QW6Y@1224|Proteobacteria,2TWQJ@28211|Alphaproteobacteria,3JS5Y@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria CH FAD binding domain MA20_40245 - - - - - - - - - - - FAD_binding_3,NAD_binding_8 CMS1_k127_3734202_35 396588.Tgr7_2880 7.383e-49 179.0 COG5615@1|root,COG5615@2|Bacteria,1RH6D@1224|Proteobacteria,1S6S2@1236|Gammaproteobacteria,1WZE3@135613|Chromatiales 135613|Chromatiales S Copper resistance protein D - - - - - - - - - - - - CopD CMS1_k127_3734202_4 1038859.AXAU01000049_gene2266 8.663e-280 866.0 COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,2TRIJ@28211|Alphaproteobacteria,3JTAW@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G phosphoglucomutase phosphomannomutase alpha beta alpha domain I algC - 5.4.2.2,5.4.2.8 ko:K15778 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00114 R00959,R01057,R01818,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV CMS1_k127_3734202_36 1038859.AXAU01000049_gene2264 6.954e-48 177.0 COG3577@1|root,COG3577@2|Bacteria,1N2PE@1224|Proteobacteria,2U61J@28211|Alphaproteobacteria,3JVUR@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S gag-polyprotein putative aspartyl protease MA20_21995 - - ko:K06985 ko04112,map04112 - - - ko00000,ko00001 - - - gag-asp_proteas CMS1_k127_3734202_45 1123242.JH636435_gene2942 3.68e-24 117.0 2E79V@1|root,331TF@2|Bacteria,2J35R@203682|Planctomycetes 203682|Planctomycetes S Pfam:DUF2029 - - - - - - - - - - - - GT87 CMS1_k127_3734202_1 316055.RPE_4818 0.0 1131.0 COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,2TRMJ@28211|Alphaproteobacteria,3JT3T@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L ATP-dependent helicase hrpB - 3.6.4.13 ko:K03579 - - - - ko00000,ko01000 - - - DEAD,HA2,Helicase_C,HrpB_C CMS1_k127_3734202_8 1187851.A33M_3593 2.432e-223 702.0 COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,2TREV@28211|Alphaproteobacteria,3FDUM@34008|Rhodovulum 28211|Alphaproteobacteria M UDP binding domain rkpK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.22 ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 M00014,M00129,M00361,M00362 R00286 RC00291 ko00000,ko00001,ko00002,ko01000 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N CMS1_k127_3734202_0 1380355.JNIJ01000007_gene3320 0.0 1383.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2TRJF@28211|Alphaproteobacteria,3JRVT@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 CMS1_k127_3734202_15 1187851.A33M_0817 6.172e-154 501.0 COG1752@1|root,COG1752@2|Bacteria,1MUI6@1224|Proteobacteria,2TUZ3@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Patatin-like phospholipase - - - ko:K07001 - - - - ko00000 - - - Patatin CMS1_k127_3734202_44 1519464.HY22_11955 4.696e-28 119.0 COG0251@1|root,COG0251@2|Bacteria 2|Bacteria J oxidation-reduction process MA20_36215 - - - - - - - - - - - Ribonuc_L-PSP CMS1_k127_3734202_40 1122132.AQYH01000010_gene3783 1.094e-39 154.0 COG1863@1|root,COG1863@2|Bacteria,1PTAV@1224|Proteobacteria,2VAA4@28211|Alphaproteobacteria,4BKUD@82115|Rhizobiaceae 28211|Alphaproteobacteria P Na+/H+ ion antiporter subunit - - - - - - - - - - - - MNHE CMS1_k127_3734202_42 631454.N177_3889 2.045e-31 129.0 COG2212@1|root,COG2212@2|Bacteria,1N6VV@1224|Proteobacteria,2UHB7@28211|Alphaproteobacteria,1JQJT@119043|Rhodobiaceae 28211|Alphaproteobacteria P Multiple resistance and pH regulation protein F (MrpF / PhaF) - - - ko:K05570 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - MrpF_PhaF CMS1_k127_3734202_43 631454.N177_3890 1.369e-28 121.0 COG1320@1|root,COG1320@2|Bacteria,1N75I@1224|Proteobacteria,2UETR@28211|Alphaproteobacteria,1JPKS@119043|Rhodobiaceae 28211|Alphaproteobacteria P Na+/H+ antiporter subunit - - - ko:K05571 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - PhaG_MnhG_YufB CMS1_k127_3734202_30 631454.N177_3891 8.953e-63 220.0 COG2111@1|root,COG2111@2|Bacteria,1N1CK@1224|Proteobacteria,2U7UT@28211|Alphaproteobacteria,1JQ4B@119043|Rhodobiaceae 28211|Alphaproteobacteria P Domain of unknown function (DUF4040) - - - ko:K05566 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - DUF4040 CMS1_k127_3734202_34 631454.N177_3892 5.47e-51 185.0 COG2111@1|root,COG2111@2|Bacteria,1N1CK@1224|Proteobacteria,2UCMV@28211|Alphaproteobacteria,1JQAD@119043|Rhodobiaceae 28211|Alphaproteobacteria P Domain related to MnhB subunit of Na+/H+ antiporter - - - ko:K05566 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - MnhB CMS1_k127_3734202_37 631454.N177_3893 1.277e-45 168.0 COG1006@1|root,COG1006@2|Bacteria,1RGU1@1224|Proteobacteria,2UA1Z@28211|Alphaproteobacteria 28211|Alphaproteobacteria P COG1006 Multisubunit Na H antiporter, MnhC subunit - - - ko:K05567 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - Oxidored_q2 CMS1_k127_3734202_10 631454.N177_3894 2.327e-190 606.0 COG0651@1|root,COG0651@2|Bacteria,1MURB@1224|Proteobacteria,2TRQ2@28211|Alphaproteobacteria,1JP3A@119043|Rhodobiaceae 28211|Alphaproteobacteria CP Proton-conducting membrane transporter nuoN2 - 1.6.5.3 ko:K00343,ko:K05568 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000,ko02000 2.A.63.1,2.A.63.2,3.D.1 - - Proton_antipo_M CMS1_k127_3734202_13 1333998.M2A_0558 1.386e-167 546.0 COG0651@1|root,COG0651@2|Bacteria,1QU5Z@1224|Proteobacteria,2U1B0@28211|Alphaproteobacteria,4BPJI@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria CP Proton-conducting membrane transporter nuoL2 - 1.6.5.3 ko:K00341,ko:K05568 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000,ko02000 2.A.63.1,2.A.63.2,3.D.1 - - Proton_antipo_M,Proton_antipo_N CMS1_k127_3734202_46 523791.Kkor_0771 1.3e-18 91.0 2EAIM@1|root,334MN@2|Bacteria,1N6XM@1224|Proteobacteria,1SF6C@1236|Gammaproteobacteria,1XKYG@135619|Oceanospirillales 135619|Oceanospirillales - - - - - - - - - - - - - - - CMS1_k127_3734202_9 1282876.BAOK01000001_gene1964 6.005e-216 683.0 COG0651@1|root,COG0651@2|Bacteria,1MV6V@1224|Proteobacteria,2TSJC@28211|Alphaproteobacteria,4BRKG@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria CP Proton-conducting membrane transporter nuoL3 - - ko:K05568 - - - - ko00000,ko02000 2.A.63.1,2.A.63.2 - - Proton_antipo_M CMS1_k127_3734202_33 1230476.C207_02813 5.874e-52 198.0 2CKRE@1|root,34B8T@2|Bacteria,1MX6I@1224|Proteobacteria,2TSDC@28211|Alphaproteobacteria,3JUEU@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF2865) - - - - - - - - - - - - DUF2865 CMS1_k127_3734202_14 1411123.JQNH01000001_gene3484 1.071e-159 511.0 COG0579@1|root,COG0579@2|Bacteria,1N0QB@1224|Proteobacteria,2TU6K@28211|Alphaproteobacteria 28211|Alphaproteobacteria S FAD dependent oxidoreductase - - - - - - - - - - - - DAO CMS1_k127_3734202_16 1211115.ALIQ01000018_gene2150 6.179e-141 459.0 COG2951@1|root,COG3409@1|root,COG2951@2|Bacteria,COG3409@2|Bacteria,1MVY0@1224|Proteobacteria,2TTVI@28211|Alphaproteobacteria,3N9WS@45404|Beijerinckiaceae 28211|Alphaproteobacteria M Transglycosylase SLT domain MA20_41385 - - - - - - - - - - - SLT_2 CMS1_k127_3734202_7 693986.MOC_3527 8.348e-238 748.0 COG1866@1|root,COG1866@2|Bacteria,1MWXN@1224|Proteobacteria,2TRC4@28211|Alphaproteobacteria,1JSQ1@119045|Methylobacteriaceae 28211|Alphaproteobacteria C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA pckA GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00170 R00341 RC00002,RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPCK_ATP CMS1_k127_3734202_25 1187851.A33M_2217 1.06e-102 341.0 COG0748@1|root,COG0748@2|Bacteria,1RFVC@1224|Proteobacteria,2TV14@28211|Alphaproteobacteria,3FDEF@34008|Rhodovulum 28211|Alphaproteobacteria P Pyridoxamine 5'-phosphate oxidase MA20_19930 - - ko:K07226 - - - - ko00000 - - - DUF2470,Putative_PNPOx,Pyrid_oxidase_2 CMS1_k127_3734202_19 316057.RPD_0367 1.058e-135 434.0 COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,2TR43@28211|Alphaproteobacteria,3JR30@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Two component transcriptional regulator, winged helix family chvI GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - ko:K14981 ko02020,map02020 M00520 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C CMS1_k127_3734202_5 652103.Rpdx1_0269 3.471e-264 826.0 COG0642@1|root,COG2205@2|Bacteria,1N17V@1224|Proteobacteria,2TS69@28211|Alphaproteobacteria,3JS5W@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Histidine kinase chvG GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 ko:K14980 ko02020,map02020 M00520 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,Sensor_TM1,Stimulus_sens_1 CMS1_k127_3734202_38 1230476.C207_02823 5.856e-45 167.0 COG1493@1|root,COG1493@2|Bacteria,1NNN5@1224|Proteobacteria,2UFPB@28211|Alphaproteobacteria,3JZX2@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T HPr Serine kinase C-terminal domain hprK - - ko:K06023 - - - - ko00000,ko01000 - - - Hpr_kinase_C CMS1_k127_3734202_31 1245469.S58_68820 4.367e-60 213.0 COG2893@1|root,COG2893@2|Bacteria,1RHH7@1224|Proteobacteria,2U9E5@28211|Alphaproteobacteria,3JY47@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G PTS system fructose IIA component manX - 2.7.1.191 ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.6.1 - - EIIA-man CMS1_k127_3734202_41 316058.RPB_0467 1.703e-33 131.0 COG1925@1|root,COG1925@2|Bacteria,1N6RM@1224|Proteobacteria,2UC0H@28211|Alphaproteobacteria,3JZF9@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G system phosphocarrier protein HPr ptsH GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006808,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0044424,GO:0044464,GO:0050789,GO:0051179,GO:0051234,GO:0065007,GO:0071702 - ko:K11189 - - - - ko00000,ko02000 4.A.2.1 - - PTS-HPr CMS1_k127_3734202_6 1187851.A33M_0457 1.502e-262 814.0 COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,2TSJY@28211|Alphaproteobacteria,3FCRQ@34008|Rhodovulum 28211|Alphaproteobacteria H May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine ahcY GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 ko:K01251 ko00270,ko01100,map00270,map01100 M00035 R00192,R04936 RC00056,RC00069,RC01161,RC01243 ko00000,ko00001,ko00002,ko01000,ko01009,ko04147 - - - AdoHcyase,AdoHcyase_NAD CMS1_k127_3734202_24 1384056.N787_01670 7.079e-108 372.0 COG0842@1|root,COG0842@2|Bacteria,1MUIA@1224|Proteobacteria,1RQSE@1236|Gammaproteobacteria,1X7D8@135614|Xanthomonadales 135614|Xanthomonadales V ABC-2 family transporter protein - - - - - - - - - - - - ABC2_membrane_3 CMS1_k127_3734202_21 450851.PHZ_p0155 1.962e-122 404.0 COG0842@1|root,COG0842@2|Bacteria,1QVX7@1224|Proteobacteria,2TX9C@28211|Alphaproteobacteria 28211|Alphaproteobacteria V ABC-2 family transporter protein - - - ko:K01992,ko:K13926 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 CMS1_k127_3734202_12 450851.PHZ_p0154 7.702e-175 567.0 COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,2TR2P@28211|Alphaproteobacteria,2KK9G@204458|Caulobacterales 204458|Caulobacterales V AAA domain, putative AbiEii toxin, Type IV TA system - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran CMS1_k127_3734202_28 450851.PHZ_p0153 1.388e-77 270.0 COG1566@1|root,COG1566@2|Bacteria,1QU7Z@1224|Proteobacteria,2TW9Z@28211|Alphaproteobacteria 28211|Alphaproteobacteria V secretion protein yhiI - - ko:K01993 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 CMS1_k127_3734202_39 224911.27351724 1.072e-41 160.0 COG1226@1|root,32YV7@2|Bacteria,1N7MV@1224|Proteobacteria,2U76Q@28211|Alphaproteobacteria,3JYY2@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P Ion channel - - - - - - - - - - - - Ion_trans_2 CMS1_k127_3734202_23 331869.BAL199_03244 2.861e-113 374.0 COG3246@1|root,COG3246@2|Bacteria,1MZTP@1224|Proteobacteria,2TQKN@28211|Alphaproteobacteria,4BPXJ@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria S beta-keto acid cleavage enzyme - - - - - - - - - - - - BKACE CMS1_k127_3734202_11 1096546.WYO_5547 1.32e-179 571.0 COG2114@1|root,COG4753@1|root,COG2114@2|Bacteria,COG4753@2|Bacteria,1PYP4@1224|Proteobacteria,2TVEP@28211|Alphaproteobacteria,1JUEA@119045|Methylobacteriaceae 28211|Alphaproteobacteria T PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_cyc,Response_reg CMS1_k127_3734202_32 1408224.SAMCCGM7_c6617 3.189e-54 198.0 COG3437@1|root,COG3437@2|Bacteria,1REES@1224|Proteobacteria,2U7TN@28211|Alphaproteobacteria,4BF65@82115|Rhizobiaceae 28211|Alphaproteobacteria KT cheY-homologous receiver domain - - - - - - - - - - - - Response_reg CMS1_k127_3734202_2 113395.AXAI01000002_gene5219 0.0 1102.0 COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TTJ0@28211|Alphaproteobacteria,3JS5D@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - - - - - - - - - - GAF,GAF_2,HAMP,HATPase_c,HisKA,PAS_7,dCache_1 CMS1_k127_3734202_27 316057.RPD_0372 1.939e-96 340.0 COG1807@1|root,COG1807@2|Bacteria,1QIUU@1224|Proteobacteria,2TWT1@28211|Alphaproteobacteria,3JTS7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - PMT_2 CMS1_k127_3734202_20 323098.Nwi_0343 4.017e-123 396.0 COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,2TR3H@28211|Alphaproteobacteria,3JR8J@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA - - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C CMS1_k127_3734786_3 349521.HCH_05884 1.505e-37 144.0 COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,1RMIV@1236|Gammaproteobacteria,1XHZM@135619|Oceanospirillales 135619|Oceanospirillales M Peptidoglycan polymerase that is essential for cell division ftsW - - ko:K03588 ko04112,map04112 - - - ko00000,ko00001,ko02000,ko03036 2.A.103.1 - - FTSW_RODA_SPOVE CMS1_k127_3734786_1 105559.Nwat_0227 2.469e-113 376.0 COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,1RMQ3@1236|Gammaproteobacteria,1WWB9@135613|Chromatiales 135613|Chromatiales M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) murG - 2.4.1.227 ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 - R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011 - GT28 - Glyco_tran_28_C,Glyco_transf_28 CMS1_k127_3734786_0 519989.ECTPHS_01879 2.324e-188 599.0 COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,1RN88@1236|Gammaproteobacteria,1WW6B@135613|Chromatiales 135613|Chromatiales M Belongs to the MurCDEF family murC - 6.3.2.8 ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M CMS1_k127_3734786_2 713586.KB900536_gene1371 7.944e-108 361.0 COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,1RNXK@1236|Gammaproteobacteria,1WW8T@135613|Chromatiales 135613|Chromatiales M Cell wall formation murB - 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 - - - FAD_binding_4,MurB_C CMS1_k127_3734786_4 292415.Tbd_0122 5.613e-22 102.0 COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,2VHIW@28216|Betaproteobacteria,1KRC8@119069|Hydrogenophilales 119069|Hydrogenophilales M D-ala D-ala ligase N-terminus - - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C,Dala_Dala_lig_N CMS1_k127_3761078_1 582744.Msip34_0504 5.371e-65 228.0 COG0352@1|root,COG0494@1|root,COG0352@2|Bacteria,COG0494@2|Bacteria,1RCZM@1224|Proteobacteria,2VHTP@28216|Betaproteobacteria,2KM02@206350|Nitrosomonadales 206350|Nitrosomonadales HL Thiamine monophosphate synthase - - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX,TMP-TENI CMS1_k127_3761078_2 1415778.JQMM01000001_gene205 1.494e-07 57.0 2AVP4@1|root,31MG5@2|Bacteria,1QJBP@1224|Proteobacteria,1THAD@1236|Gammaproteobacteria,1JBEC@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S Alanine-zipper, major outer membrane lipoprotein - - - - - - - - - - - - Alanine_zipper CMS1_k127_3761078_0 1123368.AUIS01000007_gene2702 7.353e-107 357.0 COG1376@1|root,COG1376@2|Bacteria,1MVYT@1224|Proteobacteria,1RMNC@1236|Gammaproteobacteria,2NCX3@225057|Acidithiobacillales 225057|Acidithiobacillales S L,D-transpeptidase catalytic domain - - - ko:K16291 - - - - ko00000,ko01002,ko01011 - - - LysM,YkuD CMS1_k127_3765448_5 1429916.X566_13390 2.296e-44 162.0 COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,2TSE2@28211|Alphaproteobacteria,3JS73@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C NADH NADPH, small subunit gltD - 1.4.1.13,1.4.1.14 ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - Fer4_20,Pyr_redox_2 CMS1_k127_3765448_4 323097.Nham_1133 3.966e-106 367.0 COG2845@1|root,COG2845@2|Bacteria,1R4X7@1224|Proteobacteria,2U5AU@28211|Alphaproteobacteria,3JRNF@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF459) - - - ko:K09795 - - - - ko00000 - - - DUF459 CMS1_k127_3765448_2 1187851.A33M_1210 2.915e-136 439.0 COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,2TRT6@28211|Alphaproteobacteria,3FD06@34008|Rhodovulum 28211|Alphaproteobacteria M Nucleotidyl transferase galU - 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase CMS1_k127_3765448_3 709797.CSIRO_1654 1.023e-126 425.0 COG5338@1|root,COG5338@2|Bacteria,1PFWT@1224|Proteobacteria,2U090@28211|Alphaproteobacteria,3JS4K@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Putative beta-barrel porin 2 - - - - - - - - - - - - BBP2_2 CMS1_k127_3765448_0 1038858.AXBA01000013_gene2380 3.165e-157 502.0 COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,2TSMS@28211|Alphaproteobacteria,3EY97@335928|Xanthobacteraceae 28211|Alphaproteobacteria H Catalyzes the ferrous insertion into protoporphyrin IX hemH GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R00310,R11329 RC01012 ko00000,ko00001,ko00002,ko01000 - - - Ferrochelatase CMS1_k127_3765448_1 1429916.X566_11370 3.605e-156 499.0 COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,2TQN5@28211|Alphaproteobacteria,3JSCQ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H AMP-binding enzyme MA20_42595 - 6.2.1.30 ko:K01912 ko00360,ko01120,ko05111,map00360,map01120,map05111 - R02539 RC00004,RC00014 ko00000,ko00001,ko01000 - - - AMP-binding,AMP-binding_C_2 CMS1_k127_3773390_1 1429916.X566_10060 7.693e-85 288.0 COG2885@1|root,COG2885@2|Bacteria,1PQ3A@1224|Proteobacteria,2TRBD@28211|Alphaproteobacteria,3JSN0@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M OmpA family MA20_43500 - - - - - - - - - - - OmpA CMS1_k127_3773390_2 1380355.JNIJ01000004_gene2914 2.059e-79 274.0 COG0697@1|root,COG0697@2|Bacteria,1MVHN@1224|Proteobacteria,2TRCU@28211|Alphaproteobacteria,3JVKC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA CMS1_k127_3773390_0 438753.AZC_0168 0.0 1340.0 COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,1MU2Y@1224|Proteobacteria,2TQZ6@28211|Alphaproteobacteria,3F0S7@335928|Xanthobacteraceae 28211|Alphaproteobacteria EQ Hydantoinase/oxoprolinase N-terminal region - - 3.5.2.9 ko:K01469 ko00480,map00480 - R00251 RC00553 ko00000,ko00001,ko01000 - - - Hydant_A_N,Hydantoinase_A,Hydantoinase_B CMS1_k127_3784610_4 1541065.JRFE01000061_gene5845 4.108e-07 57.0 COG0843@1|root,COG0843@2|Bacteria,1G1B0@1117|Cyanobacteria,3VIRG@52604|Pleurocapsales 1117|Cyanobacteria C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B - - 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 - - COX1 CMS1_k127_3784610_2 644966.Tmar_1595 2.193e-15 84.0 COG1622@1|root,COG1622@2|Bacteria,1TRC3@1239|Firmicutes,25348@186801|Clostridia 186801|Clostridia C Cytochrome C oxidase subunit II, periplasmic domain - - 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 - - COX2 CMS1_k127_3784610_1 1121382.JQKG01000036_gene3899 3.839e-28 131.0 COG4585@1|root,COG4585@2|Bacteria,1WIV0@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - GAF,GAF_2,GAF_3,HATPase_c,HisKA_3 CMS1_k127_3784610_0 711393.AYRX01000094_gene3836 2.042e-47 179.0 COG2197@1|root,COG2197@2|Bacteria,2GJRY@201174|Actinobacteria 201174|Actinobacteria T response regulator - - - - - - - - - - - - GerE,Response_reg CMS1_k127_3784610_3 1384056.N787_01670 3.071e-10 61.0 COG0842@1|root,COG0842@2|Bacteria,1MUIA@1224|Proteobacteria,1RQSE@1236|Gammaproteobacteria,1X7D8@135614|Xanthomonadales 135614|Xanthomonadales V ABC-2 family transporter protein - - - - - - - - - - - - ABC2_membrane_3 CMS1_k127_380993_4 631454.N177_0166 2.026e-94 317.0 COG1319@1|root,COG1319@2|Bacteria,1RCRH@1224|Proteobacteria,2TSYF@28211|Alphaproteobacteria,1JPNZ@119043|Rhodobiaceae 28211|Alphaproteobacteria C CO dehydrogenase flavoprotein C-terminal domain - - - - - - - - - - - - CO_deh_flav_C,FAD_binding_5 CMS1_k127_380993_0 631454.N177_0165 1.02e-295 918.0 COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,1MUEA@1224|Proteobacteria,2TWGU@28211|Alphaproteobacteria,1JPZB@119043|Rhodobiaceae 28211|Alphaproteobacteria C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - - - - - - - - - - Ald_Xan_dh_C,Ald_Xan_dh_C2,CO_deh_flav_C,FAD_binding_5,Fer2,Fer2_2 CMS1_k127_380993_2 666684.AfiDRAFT_3129 3.704e-164 521.0 COG1529@1|root,COG1529@2|Bacteria,1NPGE@1224|Proteobacteria,2TTCC@28211|Alphaproteobacteria,3JTHK@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Molybdopterin-binding domain of aldehyde dehydrogenase MA20_13970 - - - - - - - - - - - Ald_Xan_dh_C2 CMS1_k127_380993_6 926556.Echvi_4505 5.12e-71 250.0 COG0491@1|root,COG0491@2|Bacteria 2|Bacteria GM Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - 3.1.1.81 ko:K13075 ko02024,map02024 - R08970 RC00713 ko00000,ko00001,ko01000 - - - Lactamase_B,Lactamase_B_2 CMS1_k127_380993_3 631454.N177_0163 4.318e-141 454.0 COG1082@1|root,COG1082@2|Bacteria,1NUTW@1224|Proteobacteria 1224|Proteobacteria G Xylose isomerase-like TIM barrel - - - - - - - - - - - - AP_endonuc_2 CMS1_k127_380993_5 631454.N177_0162 1.313e-92 315.0 COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2TTFX@28211|Alphaproteobacteria,1JPR6@119043|Rhodobiaceae 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC CMS1_k127_380993_8 1120983.KB894578_gene3831 1.483e-17 88.0 2AKDB@1|root,31B4H@2|Bacteria,1Q6VV@1224|Proteobacteria,2VCYU@28211|Alphaproteobacteria,1JQKA@119043|Rhodobiaceae 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter TctB family - - - - - - - - - - - - TctB CMS1_k127_380993_1 1120983.KB894578_gene3832 9.841e-199 631.0 COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TR4Q@28211|Alphaproteobacteria,1JPU6@119043|Rhodobiaceae 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter TctA family - - - - - - - - - - - - TctA CMS1_k127_380993_7 883080.HMPREF9697_01394 2.669e-42 160.0 COG0028@1|root,COG0028@2|Bacteria,1R743@1224|Proteobacteria,2U4KA@28211|Alphaproteobacteria 28211|Alphaproteobacteria EH Thiamine pyrophosphate enzyme, central domain - - 3.7.1.22 ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 - R08603 RC02331 ko00000,ko00001,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N CMS1_k127_3820430_1 1187851.A33M_3498 8.348e-144 482.0 COG2989@1|root,COG2989@2|Bacteria,1MV14@1224|Proteobacteria,2TRJ9@28211|Alphaproteobacteria,3FCZ0@34008|Rhodovulum 28211|Alphaproteobacteria S Putative peptidoglycan binding domain - - - ko:K21470 - - - - ko00000,ko01002,ko01011 - - - PG_binding_1,YkuD CMS1_k127_3820430_0 1187851.A33M_3499 1.866e-212 671.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria,3FCZN@34008|Rhodovulum 28211|Alphaproteobacteria T Sigma-54 interaction domain tacA GO:0003674,GO:0003700,GO:0004857,GO:0006355,GO:0008073,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0010967,GO:0019219,GO:0019222,GO:0030234,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033238,GO:0042979,GO:0043086,GO:0044092,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0065009,GO:0080090,GO:0098772,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - ko:K10912 ko02020,ko02024,ko05111,map02020,map02024,map05111 M00513 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activ_2,Sigma54_activat CMS1_k127_3820430_3 331869.BAL199_04504 1.132e-82 286.0 COG0530@1|root,COG0530@2|Bacteria,1MU3R@1224|Proteobacteria,2TST5@28211|Alphaproteobacteria 28211|Alphaproteobacteria P COG0530 Ca2 Na antiporter - - - ko:K07301 - - - - ko00000,ko02000 2.A.19.5 - - Na_Ca_ex CMS1_k127_3820430_6 189753.AXAS01000016_gene1421 0.0002198 51.0 29F7S@1|root,3025F@2|Bacteria,1NBFS@1224|Proteobacteria,2UISV@28211|Alphaproteobacteria,3K16J@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_3820430_5 1429916.X566_10925 2.63e-27 112.0 COG1396@1|root,COG1396@2|Bacteria,1N6V6@1224|Proteobacteria,2UGCV@28211|Alphaproteobacteria,3K4NQ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_19,HTH_3,HTH_31 CMS1_k127_3820430_4 1380355.JNIJ01000005_gene2694 1.826e-32 131.0 2AJX4@1|root,31AK3@2|Bacteria,1NWRW@1224|Proteobacteria,2USIQ@28211|Alphaproteobacteria,3K45C@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_3820430_2 398525.KB900701_gene337 2.577e-95 323.0 COG1164@1|root,COG1164@2|Bacteria,1MXAC@1224|Proteobacteria,2TRPY@28211|Alphaproteobacteria,3JUD8@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Oligopeptidase F pepF - - ko:K08602 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3,Peptidase_M3_N CMS1_k127_3866278_6 1177179.A11A3_06201 1.324e-75 257.0 COG2368@1|root,COG2368@2|Bacteria,1PEQG@1224|Proteobacteria,1RQ3I@1236|Gammaproteobacteria,1XPZR@135619|Oceanospirillales 135619|Oceanospirillales Q COG2368 Aromatic ring hydroxylase - - - - - - - - - - - - HpaB,HpaB_N CMS1_k127_3866278_7 469381.Dpep_1415 3.424e-47 182.0 COG2301@1|root,COG2301@2|Bacteria,3TA9J@508458|Synergistetes 508458|Synergistetes G Belongs to the HpcH HpaI aldolase family - - 4.1.3.34 ko:K01644 ko02020,map02020 - R00362 RC00067,RC01118 ko00000,ko00001,ko01000 - - - HpcH_HpaI CMS1_k127_3866278_4 1054213.HMPREF9946_02427 1.162e-104 352.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TVS9@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Acyl-CoA dehydrogenase, C-terminal domain - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N CMS1_k127_3866278_3 644966.Tmar_1575 6.222e-105 354.0 COG1804@1|root,COG1804@2|Bacteria,1TP54@1239|Firmicutes,24AFB@186801|Clostridia,3WD6V@538999|Clostridiales incertae sedis 186801|Clostridia C acyl-CoA transferase carnitine dehydratase - - 2.8.3.19 ko:K18702 - - - - ko00000,ko01000 - - - CoA_transf_3 CMS1_k127_3866278_8 1449357.JQLK01000001_gene1177 1.161e-42 161.0 COG2030@1|root,COG2030@2|Bacteria,1WJC4@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus I N-terminal half of MaoC dehydratase - - - - - - - - - - - - MaoC_dehydratas CMS1_k127_3866278_0 709797.CSIRO_2934 1.667e-294 920.0 COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,2TRTY@28211|Alphaproteobacteria,3JQS3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T CHASE2 cyaD - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - CHASE2,Guanylate_cyc CMS1_k127_3866278_2 1197906.CAJQ02000011_gene737 8.822e-174 556.0 COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,2TSP0@28211|Alphaproteobacteria,3JT9C@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M TIGRFAM type I secretion membrane fusion protein, HlyD family MA20_19340 - - ko:K02022 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD,HlyD_3 CMS1_k127_3866278_1 883078.HMPREF9695_01863 5.732e-242 760.0 COG4618@1|root,COG4618@2|Bacteria,1NTI5@1224|Proteobacteria,2TR17@28211|Alphaproteobacteria,3JRPY@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria V ABC transporter transmembrane region MA20_19345 - - ko:K06148 - - - - ko00000,ko02000 3.A.1 - - ABC_membrane,ABC_tran CMS1_k127_3866278_5 196490.AUEZ01000016_gene3159 1.677e-79 287.0 COG0823@1|root,COG2931@1|root,COG3468@1|root,COG4254@1|root,COG4932@1|root,COG0823@2|Bacteria,COG2931@2|Bacteria,COG3468@2|Bacteria,COG4254@2|Bacteria,COG4932@2|Bacteria,1MU7T@1224|Proteobacteria,2TV0C@28211|Alphaproteobacteria,3JS2H@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria QU FecR protein - - - - - - - - - - - - Cadherin_3,FecR,HemolysinCabind,Laminin_G_3,VWA CMS1_k127_3866278_9 1005395.CSV86_27833 6.414e-06 59.0 COG2931@1|root,COG5625@1|root,COG2931@2|Bacteria,COG5625@2|Bacteria,1MU7T@1224|Proteobacteria,1RMZW@1236|Gammaproteobacteria,1YZKD@136845|Pseudomonas putida group 1236|Gammaproteobacteria Q von Willebrand factor (vWF) type A domain lapA - - ko:K12549 - - - - ko00000 - - - Big_3_2,Cadherin_3,Calx-beta,HemolysinCabind,VCBS,VWA,VWA_2 CMS1_k127_3870748_1 585529.HMPREF0291_11942 8.039e-05 50.0 COG3064@1|root,COG3064@2|Bacteria 2|Bacteria M translation initiation factor activity - - - ko:K08930 ko02020,map02020 - - - ko00000,ko00001,ko00194 - - - VPEP CMS1_k127_3870748_0 1187851.A33M_2182 1.172e-107 357.0 COG1338@1|root,COG1338@2|Bacteria,1MVBU@1224|Proteobacteria,2TT93@28211|Alphaproteobacteria,3FD14@34008|Rhodovulum 28211|Alphaproteobacteria N Plays a role in the flagellum-specific transport system fliP - - ko:K02419 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - FliP CMS1_k127_3870748_2 40492.XP_007308539.1 0.0002511 49.0 COG1404@1|root,KOG3525@2759|Eukaryota,38EIV@33154|Opisthokonta,3P3I8@4751|Fungi,3V0QE@5204|Basidiomycota,22531@155619|Agaricomycetes,3H44G@355688|Agaricomycetes incertae sedis 4751|Fungi T EGF domain, unclasssified subfamily - - - - - - - - - - - - Furin-like_2 CMS1_k127_3871132_2 189753.AXAS01000010_gene7405 0.0003438 43.0 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TR8X@28211|Alphaproteobacteria,3JRJI@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Histidine kinase-like ATPases - - - - - - - - - - - - DUF4118,HATPase_c,HisKA,PAS_3,PAS_9 CMS1_k127_3871132_1 663610.JQKO01000007_gene2310 1.656e-30 131.0 COG0236@1|root,COG0236@2|Bacteria,1NHIC@1224|Proteobacteria,2UFUJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria IQ Phosphopantetheine attachment site - - - - - - - - - - - - PP-binding CMS1_k127_3871132_0 663610.JQKO01000007_gene2309 1.622e-147 475.0 COG0508@1|root,COG0508@2|Bacteria,1MUGY@1224|Proteobacteria,2TRXM@28211|Alphaproteobacteria,3N9QV@45404|Beijerinckiaceae 28211|Alphaproteobacteria C 2-oxoacid dehydrogenases acyltransferase (catalytic domain) - - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding CMS1_k127_3913680_4 1177928.TH2_18356 6.575e-64 220.0 COG1024@1|root,COG1024@2|Bacteria,1MXHV@1224|Proteobacteria,2TTEG@28211|Alphaproteobacteria,2JQRS@204441|Rhodospirillales 204441|Rhodospirillales I COG1024 Enoyl-CoA hydratase carnithine racemase - - - - - - - - - - - - ECH_1 CMS1_k127_3913680_1 1547437.LL06_13995 5.465e-171 546.0 COG1960@1|root,COG1960@2|Bacteria,1MVQH@1224|Proteobacteria,2TTX8@28211|Alphaproteobacteria,43J1N@69277|Phyllobacteriaceae 28211|Alphaproteobacteria I acyl-CoA dehydrogenase - - 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N CMS1_k127_3913680_0 1038860.AXAP01000027_gene1872 6.784e-301 930.0 COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2TR3P@28211|Alphaproteobacteria,3JQQ5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I benzoate-CoA ligase MA20_38120 - 6.2.1.32 ko:K08295 ko00627,ko01120,map00627,map01120 - R00982 RC00004,RC00174 ko00000,ko00001,ko01000 - - - AMP-binding,AMP-binding_C CMS1_k127_3913680_5 760117.JN27_04785 4.491e-47 173.0 COG0251@1|root,COG0251@2|Bacteria,1RHSP@1224|Proteobacteria,2VSJ7@28216|Betaproteobacteria,47795@75682|Oxalobacteraceae 28216|Betaproteobacteria J Endoribonuclease L-PSP abmE - - - - - - - - - - - Ribonuc_L-PSP CMS1_k127_3913680_2 1392838.AWNM01000035_gene284 2.29e-153 500.0 COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VMYW@28216|Betaproteobacteria,3T3PZ@506|Alcaligenaceae 28216|Betaproteobacteria C CoA-transferase family III - - - - - - - - - - - - CoA_transf_3 CMS1_k127_3913680_3 1469245.JFBG01000075_gene155 8.269e-82 274.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RMMJ@1236|Gammaproteobacteria,1WWVA@135613|Chromatiales 1236|Gammaproteobacteria I Acyl-CoA dehydrogenase, C-terminal domain - - - ko:K18244 - - - - ko00000,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N CMS1_k127_3916530_1 1038860.AXAP01000048_gene6832 2.349e-88 295.0 COG1028@1|root,COG1028@2|Bacteria,1MUBQ@1224|Proteobacteria,2TRPN@28211|Alphaproteobacteria,3JU36@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria IQ Belongs to the short-chain dehydrogenases reductases (SDR) family MA20_18715 - - - - - - - - - - - adh_short CMS1_k127_3916530_2 1502724.FF80_00654 2.167e-37 145.0 COG0824@1|root,COG0824@2|Bacteria,1PH9G@1224|Proteobacteria,2VBB1@28211|Alphaproteobacteria,3N8QD@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria S Thioesterase-like superfamily - - 3.1.2.23 ko:K01075 ko00130,ko00362,ko01100,ko01110,ko01120,map00130,map00362,map01100,map01110,map01120 - R01301 RC00004,RC00174 ko00000,ko00001,ko01000 - - - 4HBT CMS1_k127_3916530_3 1218074.BAXZ01000025_gene4470 1.673e-34 138.0 COG1846@1|root,COG1846@2|Bacteria,1N7PQ@1224|Proteobacteria,2VV8Y@28216|Betaproteobacteria,1KB3F@119060|Burkholderiaceae 28216|Betaproteobacteria K helix_turn_helix multiple antibiotic resistance protein - - - - - - - - - - - - MarR,MarR_2 CMS1_k127_3916530_0 1244869.H261_01676 8.97e-164 522.0 COG4231@1|root,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,2TSHH@28211|Alphaproteobacteria,2JSZE@204441|Rhodospirillales 204441|Rhodospirillales C Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates - - - - - - - - - - - - TPP_enzyme_C CMS1_k127_3921480_15 652103.Rpdx1_3435 1.842e-122 407.0 COG3278@1|root,COG3278@2|Bacteria,1PU2D@1224|Proteobacteria,2U5ID@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Belongs to the heme-copper respiratory oxidase family - - - - - - - - - - - - - CMS1_k127_3921480_33 1150469.RSPPHO_01831 4.105e-44 173.0 COG0454@1|root,COG0456@2|Bacteria,1N43K@1224|Proteobacteria,2UDB6@28211|Alphaproteobacteria,2JTG2@204441|Rhodospirillales 204441|Rhodospirillales K Acetyltransferase (GNAT) family - - - - - - - - - - - - Acetyltransf_1 CMS1_k127_3921480_37 1430440.MGMSRv2_1302 8.02e-34 136.0 COG1959@1|root,COG1959@2|Bacteria,1PZ79@1224|Proteobacteria,2UCUA@28211|Alphaproteobacteria,2JTF5@204441|Rhodospirillales 204441|Rhodospirillales K transcriptional regulator - - - - - - - - - - - - Rrf2 CMS1_k127_3921480_20 316057.RPD_1522 8.87e-101 334.0 COG0664@1|root,COG0664@2|Bacteria,1R5P7@1224|Proteobacteria,2TV0F@28211|Alphaproteobacteria,3JZ04@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K Cyclic nucleotide-monophosphate binding domain hbaR - - ko:K21563 - - - - ko00000,ko03000 - - - HTH_Crp_2,cNMP_binding CMS1_k127_3921480_29 1244869.H261_12176 1.182e-53 193.0 COG0251@1|root,COG0251@2|Bacteria,1RHSP@1224|Proteobacteria,2U9A9@28211|Alphaproteobacteria,2JSX2@204441|Rhodospirillales 204441|Rhodospirillales J translation initiation inhibitor, yjgF family - - - - - - - - - - - - Ribonuc_L-PSP CMS1_k127_3921480_16 652103.Rpdx1_4114 7.483e-120 397.0 COG1319@1|root,COG1319@2|Bacteria,1MVJS@1224|Proteobacteria,2U506@28211|Alphaproteobacteria 28211|Alphaproteobacteria C CO dehydrogenase flavoprotein C-terminal domain - - 1.3.7.9 ko:K04109 ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220 - R05316 RC00490 ko00000,ko00001,ko01000 - - - CO_deh_flav_C,FAD_binding_5 CMS1_k127_3921480_0 316055.RPE_0590 0.0 1251.0 COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TWGU@28211|Alphaproteobacteria,3JQT8@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - 1.17.1.4,1.2.5.3,1.3.7.9 ko:K00087,ko:K03520,ko:K04108 ko00230,ko00362,ko00627,ko01100,ko01120,ko01220,map00230,map00362,map00627,map01100,map01120,map01220 M00546 R01768,R02103,R05316,R11168 RC00143,RC00490,RC02800 ko00000,ko00001,ko00002,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2 CMS1_k127_3921480_25 316055.RPE_0591 1.066e-76 261.0 COG2080@1|root,COG2080@2|Bacteria,1MWA6@1224|Proteobacteria,2TS73@28211|Alphaproteobacteria 28211|Alphaproteobacteria C aerobic-type carbon monoxide dehydrogenase, small subunit CoxS MA20_13960 - 1.2.5.3,1.3.7.9 ko:K03518,ko:K04107 ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220 - R05316,R11168 RC00490,RC02800 ko00000,ko00001,ko01000 - - - Fer2,Fer2_2 CMS1_k127_3921480_5 316057.RPD_1526 2.371e-250 781.0 COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2TR3P@28211|Alphaproteobacteria,3JQQ5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I benzoate-CoA ligase - - 6.2.1.25,6.2.1.27 ko:K04105 ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220 - R01300,R01422 RC00004,RC00174 ko00000,ko00001,ko01000 - - - AMP-binding,AMP-binding_C CMS1_k127_3921480_10 670292.JH26_12415 1.078e-167 537.0 COG1960@1|root,COG1960@2|Bacteria,1MVQH@1224|Proteobacteria,2TTX8@28211|Alphaproteobacteria,1JX8D@119045|Methylobacteriaceae 28211|Alphaproteobacteria I Acyl-CoA dehydrogenase, middle domain - - 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N CMS1_k127_3921480_11 1244869.H261_15647 4.509e-157 504.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TQKE@28211|Alphaproteobacteria,2JPPM@204441|Rhodospirillales 204441|Rhodospirillales I COG1960 Acyl-CoA dehydrogenases - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N CMS1_k127_3921480_24 1244869.H261_01207 7.163e-80 278.0 COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,2TRYS@28211|Alphaproteobacteria,2JPVP@204441|Rhodospirillales 204441|Rhodospirillales I Belongs to the enoyl-CoA hydratase isomerase family - - - - - - - - - - - - ECH_1 CMS1_k127_3921480_22 76114.ebA723 2.39e-86 293.0 COG1028@1|root,COG1028@2|Bacteria,1RCD5@1224|Proteobacteria,2W04R@28216|Betaproteobacteria,2KXRA@206389|Rhodocyclales 206389|Rhodocyclales IQ KR domain - - - ko:K07535 ko00362,ko01120,ko01220,map00362,map01120,map01220 M00540 R05582 RC00154 ko00000,ko00001,ko00002,ko01000 - - - adh_short_C2 CMS1_k127_3921480_12 1187851.A33M_3177 3.916e-133 430.0 COG1024@1|root,COG1024@2|Bacteria,1MVQN@1224|Proteobacteria,2TUXD@28211|Alphaproteobacteria,3FE0K@34008|Rhodovulum 28211|Alphaproteobacteria I Enoyl-CoA hydratase/isomerase - - 5.3.3.18 ko:K15866 ko00360,ko01120,map00360,map01120 - R09837,R09839 RC00004,RC00326,RC02689,RC03003 ko00000,ko00001,ko01000 - - - ECH_1 CMS1_k127_3921480_31 883078.HMPREF9695_00881 2.192e-48 179.0 COG3474@1|root,COG3474@2|Bacteria,1MZGS@1224|Proteobacteria,2UCUT@28211|Alphaproteobacteria,3JY3A@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Cytochrome c cycA GO:0005575,GO:0005623,GO:0042597,GO:0044464 - ko:K08738 ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.6 - - Cytochrom_C CMS1_k127_3921480_32 1122194.AUHU01000004_gene1502 1.705e-46 179.0 COG1670@1|root,COG1670@2|Bacteria,1RB1I@1224|Proteobacteria,1S7ZE@1236|Gammaproteobacteria,467KT@72275|Alteromonadaceae 1236|Gammaproteobacteria J Domain of unknown function (DUF4202) - - - - - - - - - - - - DUF4202 CMS1_k127_3921480_19 1245469.S58_68230 9.075e-102 342.0 COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,2TRUU@28211|Alphaproteobacteria,3JTZN@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein nosX - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE CMS1_k127_3921480_2 1245469.S58_68220 5.492e-299 932.0 COG0348@1|root,COG3901@1|root,COG0348@2|Bacteria,COG3901@2|Bacteria,1MY5M@1224|Proteobacteria,2TR0X@28211|Alphaproteobacteria,3JV8E@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria CK FMN_bind nirI - - ko:K19339,ko:K19343 - - - - ko00000,ko03000 - - - FMN_bind,Fer4_5 CMS1_k127_3921480_1 1245469.S58_68210 0.0 1014.0 COG2010@1|root,COG2010@2|Bacteria,1N3PN@1224|Proteobacteria,2U2TJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria C nitrite reductase nirS GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.7.2.1,1.7.99.1 ko:K15864 ko00910,ko01120,map00910,map01120 M00529 R00143,R00783,R00785 RC00086,RC02797 ko00000,ko00001,ko00002,ko01000 - - - Cytochrom_D1,Cytochrome_CBB3 CMS1_k127_3921480_18 1245469.S58_68200 6.592e-104 344.0 COG0007@1|root,COG0007@2|Bacteria,1MUI0@1224|Proteobacteria,2TRJC@28211|Alphaproteobacteria,3JT91@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme nirE - 1.3.1.76,2.1.1.107,4.99.1.4 ko:K02302,ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02864,R03194,R03947 RC00003,RC00871,RC01012,RC01034 ko00000,ko00001,ko00002,ko01000 - - - CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase CMS1_k127_3921480_38 1245469.S58_68190 1.199e-33 132.0 COG2010@1|root,COG2010@2|Bacteria,1N73U@1224|Proteobacteria,2UGBE@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Cytochrome C oxidase, cbb3-type, subunit III nirC GO:0005575,GO:0005623,GO:0042597,GO:0044464 - ko:K19344 - - - - ko00000 - - - Cytochrome_CBB3 CMS1_k127_3921480_8 1245469.S58_68180 1.747e-188 600.0 COG3391@1|root,COG3391@2|Bacteria,1QD5Q@1224|Proteobacteria,2TVCB@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Cytochrome D1 heme domain nirF - - ko:K19345 - - - - ko00000 - - - Cytochrom_D1 CMS1_k127_3921480_17 1245469.S58_68170 5.78e-109 367.0 COG1522@1|root,COG1522@2|Bacteria,1NVYY@1224|Proteobacteria,2U1S8@28211|Alphaproteobacteria 28211|Alphaproteobacteria K overlaps another CDS with the same product name nirD - - - - - - - - - - - HTH_AsnC-type CMS1_k127_3921480_28 1245469.S58_68160 1.594e-61 217.0 COG1522@1|root,COG1522@2|Bacteria,1RIKY@1224|Proteobacteria,2U81N@28211|Alphaproteobacteria 28211|Alphaproteobacteria K COG1522 Transcriptional regulators nirG - - - - - - - - - - - HTH_AsnC-type CMS1_k127_3921480_9 1454004.AW11_00135 4.673e-175 557.0 COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,2VJD9@28216|Betaproteobacteria,1KR26@119066|unclassified Betaproteobacteria 28216|Betaproteobacteria C 4Fe-4S single cluster domain nirJ - - - - - - - - - - - Fer4_12,Radical_SAM,SPASM CMS1_k127_3921480_4 1245469.S58_68130 4.566e-265 823.0 COG2010@1|root,COG3391@1|root,COG2010@2|Bacteria,COG3391@2|Bacteria,1PYK3@1224|Proteobacteria,2TVHI@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Cytochrome D1 heme domain nirN - - - - - - - - - - - Cytochrom_D1,Cytochrome_CBB3 CMS1_k127_3921480_30 1245469.S58_68120 1.153e-48 184.0 COG2138@1|root,COG2138@2|Bacteria,1ND4B@1224|Proteobacteria,2UI9T@28211|Alphaproteobacteria,3K54T@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S CbiX - - - - - - - - - - - - CbiX CMS1_k127_3921480_41 1123360.thalar_02883 1.494e-14 75.0 2ERCE@1|root,33IY3@2|Bacteria,1NNN9@1224|Proteobacteria,2UXY5@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_3921480_23 1123360.thalar_02884 9.602e-82 276.0 COG1622@1|root,COG1622@2|Bacteria,1NZNI@1224|Proteobacteria,2UJSY@28211|Alphaproteobacteria 28211|Alphaproteobacteria C cytochrome c oxidase (Subunit II) - - - - - - - - - - - - - CMS1_k127_3921480_3 1123360.thalar_02885 4.269e-287 891.0 COG0843@1|root,COG0843@2|Bacteria,1R57U@1224|Proteobacteria,2U068@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Cytochrome C and Quinol oxidase polypeptide I - - 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 - - COX1 CMS1_k127_3921480_21 1123360.thalar_02886 1.738e-86 295.0 COG0109@1|root,COG0109@2|Bacteria,1MW3S@1224|Proteobacteria,2TRD8@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group ctaB - 2.5.1.141 ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 M00154 R07411 RC01786 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 - - - UbiA CMS1_k127_3921480_27 1123360.thalar_02887 7.351e-65 235.0 COG1999@1|root,COG1999@2|Bacteria 2|Bacteria M signal sequence binding sco - - ko:K07152 - - - - ko00000,ko03029 - - - SCO1-SenC CMS1_k127_3921480_7 1123360.thalar_02888 4.48e-189 604.0 COG1145@1|root,COG1290@1|root,COG1908@1|root,COG1145@2|Bacteria,COG1290@2|Bacteria,COG1908@2|Bacteria,1QSPU@1224|Proteobacteria,2UQID@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Methyl-viologen-reducing hydrogenase, delta subunit - - - - - - - - - - - - Cytochrome_B,FlpD CMS1_k127_3921480_34 522306.CAP2UW1_1325 8.963e-41 156.0 2CB7M@1|root,31H4T@2|Bacteria,1MYWT@1224|Proteobacteria,2VSTJ@28216|Betaproteobacteria 28216|Betaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_3921480_35 1123360.thalar_02890 1.3e-36 142.0 COG2703@1|root,COG2703@2|Bacteria 2|Bacteria P oxygen carrier activity - - - ko:K07216 - - - - ko00000 - - - Hemerythrin CMS1_k127_3921480_26 1122214.AQWH01000002_gene4339 2.071e-74 256.0 COG4094@1|root,COG4094@2|Bacteria,1RDV6@1224|Proteobacteria,2U609@28211|Alphaproteobacteria 28211|Alphaproteobacteria S NnrU family nnrU - - - - - - - - - - - NnrU CMS1_k127_3921480_14 460265.Mnod_2105 5.737e-123 406.0 COG3213@1|root,COG3213@2|Bacteria,1MUJK@1224|Proteobacteria,2TSQ2@28211|Alphaproteobacteria,1JT7N@119045|Methylobacteriaceae 28211|Alphaproteobacteria P PFAM NnrS family protein nnrS - - ko:K07234 - - - - ko00000 - - - NnrS CMS1_k127_3921480_6 1187851.A33M_0326 2.473e-248 772.0 COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,2TRT0@28211|Alphaproteobacteria,3FCKB@34008|Rhodovulum 28211|Alphaproteobacteria M Belongs to the MurCDEF family murC - 6.3.2.8 ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M CMS1_k127_3921480_13 1187851.A33M_4320 3.458e-129 430.0 COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,2TRQR@28211|Alphaproteobacteria,3FCT7@34008|Rhodovulum 28211|Alphaproteobacteria M Cell wall formation murB - 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 - - - FAD_binding_4,MurB_C CMS1_k127_3921480_39 1449351.RISW2_06795 1.27e-28 122.0 COG0457@1|root,COG0457@2|Bacteria,1PIGT@1224|Proteobacteria,2U93V@28211|Alphaproteobacteria 28211|Alphaproteobacteria S COG0457 FOG TPR repeat - - - - - - - - - - - - TPR_19,TPR_2,TPR_8 CMS1_k127_3921480_36 1297863.APJF01000013_gene3939 9.748e-35 134.0 COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,2TREC@28211|Alphaproteobacteria,3JR9C@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Belongs to the D-alanine--D-alanine ligase family ddl - 1.3.1.98,6.3.2.4 ko:K00075,ko:K01921 ko00473,ko00520,ko00550,ko01100,ko01502,map00473,map00520,map00550,map01100,map01502 - R01150,R03191,R03192 RC00064,RC00141,RC02639 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C,Dala_Dala_lig_N CMS1_k127_3926655_1 1297865.APJD01000011_gene6757 1.6e-211 662.0 COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,2TRSR@28211|Alphaproteobacteria,3JUF4@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Putative modulator of DNA gyrase tldD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K03568 - - - - ko00000,ko01002 - - - PmbA_TldD CMS1_k127_3926655_8 648885.KB316283_gene3595 3.229e-05 52.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2TQR7@28211|Alphaproteobacteria,1JR8G@119045|Methylobacteriaceae 28211|Alphaproteobacteria NT PAS domain - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal,PAS_3,PAS_4,PilZ CMS1_k127_3926655_5 582899.Hden_0829 1.235e-18 91.0 COG2940@1|root,COG2940@2|Bacteria,1N3VM@1224|Proteobacteria,2UDY0@28211|Alphaproteobacteria,3N93Y@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria S SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain - - - ko:K07117 - - - - ko00000 - - - SET CMS1_k127_3926655_7 110319.CF8_3653 1.586e-11 74.0 COG3971@1|root,COG3971@2|Bacteria,2GM4Z@201174|Actinobacteria,4DV2K@85009|Propionibacteriales 201174|Actinobacteria Q 4-oxalocrotonate decarboxylase - - 4.1.1.77 ko:K01617 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 M00569 R02602,R05374 RC00751,RC02672 ko00000,ko00001,ko00002,ko01000 - - - FAA_hydrolase CMS1_k127_3926655_6 1038867.AXAY01000009_gene5577 2.207e-16 85.0 COG0662@1|root,COG0662@2|Bacteria,1P7SH@1224|Proteobacteria,2UW18@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Cupin domain - - - - - - - - - - - - Cupin_2 CMS1_k127_3926655_4 485913.Krac_9361 5.866e-80 276.0 COG2084@1|root,COG2084@2|Bacteria,2G8RG@200795|Chloroflexi 200795|Chloroflexi C PFAM 6-phosphogluconate dehydrogenase NAD-binding - - 1.1.1.31 ko:K00020 ko00280,ko01100,map00280,map01100 - R05066 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 CMS1_k127_3926655_9 316055.RPE_2236 0.0001193 46.0 COG1429@1|root,COG1429@2|Bacteria,1MU5W@1224|Proteobacteria,2TQVD@28211|Alphaproteobacteria,3JUQP@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H CobN/Magnesium Chelatase cobN - 6.6.1.2 ko:K02230 ko00860,ko01100,map00860,map01100 - R05227 RC02000 ko00000,ko00001,ko01000 - - - CobN-Mg_chel CMS1_k127_3926655_3 323097.Nham_0254 2.789e-81 273.0 COG5342@1|root,COG5342@2|Bacteria,1NA8M@1224|Proteobacteria,2TSY3@28211|Alphaproteobacteria,3JR3U@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Invasion associated locus B (IalB) protein MA20_19790 - - - - - - - - - - - IalB CMS1_k127_3926655_2 1187851.A33M_3076 1.306e-120 393.0 COG1622@1|root,COG1622@2|Bacteria,1MWHZ@1224|Proteobacteria,2TRK6@28211|Alphaproteobacteria,3FE23@34008|Rhodovulum 28211|Alphaproteobacteria C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) coxB - 1.9.3.1 ko:K02275 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.4,3.D.4.6 - - COX2,COX2_TM CMS1_k127_3926655_0 1380355.JNIJ01000010_gene1522 1.362e-313 964.0 COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,2TQP1@28211|Alphaproteobacteria,3JTJ5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B ctaD GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 ko:K02274 ko00190,ko01100,map00190,map01100 M00155 R00081 RC00016 ko00000,ko00001,ko00002,ko01000 3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6 - - COX1 CMS1_k127_3938311_0 1411123.JQNH01000001_gene2548 3.254e-210 659.0 COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,2TR96@28211|Alphaproteobacteria 28211|Alphaproteobacteria IQ COG0318, Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II MA20_29420 - 6.2.1.48 ko:K00666,ko:K02182 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C CMS1_k127_3938311_1 179408.Osc7112_6220 3.39e-41 164.0 COG0457@1|root,COG0457@2|Bacteria,1G5VM@1117|Cyanobacteria,1HE7X@1150|Oscillatoriales 1117|Cyanobacteria S PFAM Tetratricopeptide repeat - - - - - - - - - - - - TPR_1,TPR_11,TPR_16,TPR_2,TPR_8,Trypsin_2 CMS1_k127_3938311_2 652103.Rpdx1_1172 3.394e-25 107.0 COG0730@1|root,COG0730@2|Bacteria,1MVY3@1224|Proteobacteria,2TU6M@28211|Alphaproteobacteria,3JWBV@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Sulfite exporter TauE/SafE - - - ko:K07090 - - - - ko00000 - - - TauE CMS1_k127_3954297_8 1197906.CAJQ02000062_gene4756 5.286e-07 60.0 COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TQMW@28211|Alphaproteobacteria,3JUMW@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain coxL - 1.2.5.3 ko:K03520 - - R11168 RC02800 ko00000,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 CMS1_k127_3954297_4 1336235.JAEG01000009_gene2797 4.419e-86 286.0 COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,2U5BM@28211|Alphaproteobacteria,4BAGY@82115|Rhizobiaceae 28211|Alphaproteobacteria C carbon monoxide dehydrogenase coxS - 1.2.5.3 ko:K03518 - - R11168 RC02800 ko00000,ko01000 - - - Fer2,Fer2_2 CMS1_k127_3954297_2 1197906.CAJQ02000062_gene4754 3.492e-130 421.0 COG1319@1|root,COG1319@2|Bacteria,1MUDB@1224|Proteobacteria,2TTJF@28211|Alphaproteobacteria,3JR5X@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C CO dehydrogenase flavoprotein C-terminal domain coxM - 1.2.5.3 ko:K03519 - - R11168 RC02800 ko00000,ko01000 - - - CO_deh_flav_C,FAD_binding_5 CMS1_k127_3954297_3 1411123.JQNH01000001_gene1489 2.525e-105 358.0 COG3279@1|root,COG3300@1|root,COG3279@2|Bacteria,COG3300@2|Bacteria,1PXIQ@1224|Proteobacteria,2TT3B@28211|Alphaproteobacteria 28211|Alphaproteobacteria KT Carbon monoxide dehydrogenase operon C protein coxC GO:0006355,GO:0006808,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - ko:K21696 - - - - ko00000,ko03000 - - - LytTR,MHYT CMS1_k127_3954297_1 1120983.KB894572_gene2926 1.582e-180 571.0 COG2141@1|root,COG2141@2|Bacteria,1PFU1@1224|Proteobacteria,2VA1B@28211|Alphaproteobacteria,1JQ6W@119043|Rhodobiaceae 28211|Alphaproteobacteria C Luciferase-like monooxygenase - - 1.14.13.107 ko:K14733 ko00903,map00903 - R06398,R09385,R09389,R09393 RC01506 ko00000,ko00001,ko01000 - - - Bac_luciferase CMS1_k127_3954297_7 1298867.AUES01000011_gene5567 2.247e-35 153.0 2CPI3@1|root,32SJ7@2|Bacteria,1N1IR@1224|Proteobacteria,2UBVS@28211|Alphaproteobacteria,3JY4X@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF992) - - - - - - - - - - - - DUF992 CMS1_k127_3954297_6 1123229.AUBC01000005_gene810 1.244e-57 219.0 COG0840@1|root,COG3290@1|root,COG0840@2|Bacteria,COG3290@2|Bacteria,1MU9B@1224|Proteobacteria,2TQR7@28211|Alphaproteobacteria,3JWSQ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria NT Single cache domain 3 MA20_35710 - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - Cache_3-Cache_2,HAMP,MCPsignal,sCache_3_3 CMS1_k127_3954297_5 296591.Bpro_0973 1.715e-73 250.0 COG3193@1|root,COG3193@2|Bacteria,1RB2H@1224|Proteobacteria,2VQCV@28216|Betaproteobacteria 28216|Betaproteobacteria S protein possibly involved in utilization of glycolate and propanediol - - - - - - - - - - - - Haem_degrading CMS1_k127_3954297_0 1123060.JONP01000011_gene3068 1.198e-224 715.0 COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TQMW@28211|Alphaproteobacteria 28211|Alphaproteobacteria C COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs - - 1.2.5.3 ko:K03520 - - R11168 RC02800 ko00000,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 CMS1_k127_3961233_2 1120792.JAFV01000001_gene2516 6.008e-35 134.0 COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,2TRBQ@28211|Alphaproteobacteria,36XIW@31993|Methylocystaceae 28211|Alphaproteobacteria C 2-oxoglutarate dehydrogenase C-terminal sucA - 1.2.4.2 ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R00621,R01933,R01940,R03316,R08549 RC00004,RC00027,RC00627,RC02743,RC02833,RC02883 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr CMS1_k127_3961233_0 323098.Nwi_0423 1.12e-193 612.0 COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,2TS5N@28211|Alphaproteobacteria,3JR1I@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) sucB - 2.3.1.61 ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00032 R02570,R02571,R08549 RC00004,RC02727,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding CMS1_k127_3961233_3 316055.RPE_2723 7.517e-06 48.0 COG4953@1|root,COG4953@2|Bacteria,1MUA9@1224|Proteobacteria,2TR2R@28211|Alphaproteobacteria,3JS2X@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Penicillin-Binding Protein C-terminus Family pbpC - 2.4.1.129 ko:K05367 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - BiPBP_C,Transgly,Transpeptidase CMS1_k127_3961233_1 1120792.JAFV01000001_gene2512 9.985e-116 379.0 COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2TRN7@28211|Alphaproteobacteria,36XSB@31993|Methylocystaceae 28211|Alphaproteobacteria C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain lpdA GO:0000166,GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009507,GO:0009536,GO:0010035,GO:0010038,GO:0016020,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0017076,GO:0019866,GO:0030554,GO:0030964,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045271,GO:0046686,GO:0046872,GO:0046914,GO:0048046,GO:0050896,GO:0050897,GO:0055114,GO:0070469,GO:0097159,GO:0097367,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim CMS1_k127_3980083_3 257310.BB0122 2.042e-135 441.0 COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2VJDZ@28216|Betaproteobacteria,3T8XM@506|Alcaligenaceae 28216|Betaproteobacteria E DegT/DnrJ/EryC1/StrS aminotransferase family - - - - - - - - - - - - DegT_DnrJ_EryC1 CMS1_k127_3980083_0 1230476.C207_01250 5.105e-165 523.0 COG0451@1|root,COG0451@2|Bacteria,1MVI8@1224|Proteobacteria,2TT7Q@28211|Alphaproteobacteria,3K62B@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M 3-beta hydroxysteroid dehydrogenase/isomerase family - - 5.1.3.2,5.1.3.7 ko:K01784,ko:K02473 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R00418,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase CMS1_k127_3980083_4 1121101.HMPREF1532_04047 4.438e-40 160.0 COG1044@1|root,COG1044@2|Bacteria,4NU6A@976|Bacteroidetes,2FYAP@200643|Bacteroidia,4AU9N@815|Bacteroidaceae 976|Bacteroidetes M Hexapeptide repeat of succinyl-transferase - - 2.3.1.191 ko:K02536 ko00540,ko01100,map00540,map01100 M00060 R04550 RC00039,RC00166 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Hexapep CMS1_k127_3980083_1 709797.CSIRO_3832 2.104e-140 455.0 COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2TRIQ@28211|Alphaproteobacteria,3JSYW@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Belongs to the DegT DnrJ EryC1 family MA20_07980 - - - - - - - - - - - DegT_DnrJ_EryC1 CMS1_k127_3980083_2 1316936.K678_09433 4.961e-138 446.0 COG0110@1|root,COG0673@1|root,COG0110@2|Bacteria,COG0673@2|Bacteria,1MZV9@1224|Proteobacteria,2TWJW@28211|Alphaproteobacteria,2JTP3@204441|Rhodospirillales 204441|Rhodospirillales S Bacterial transferase hexapeptide (six repeats) - - - - - - - - - - - - GFO_IDH_MocA,Hexapep,Hexapep_2 CMS1_k127_3999262_6 1280944.HY17_05480 1.194e-41 154.0 296ZZ@1|root,2ZU8H@2|Bacteria,1RED2@1224|Proteobacteria,2U6CK@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_3999262_3 1120983.KB894571_gene2474 6.798e-103 341.0 COG0625@1|root,COG0625@2|Bacteria,1R6UY@1224|Proteobacteria,2U1WS@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Glutathione S-transferase, C-terminal domain - - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_C_2,GST_N,GST_N_3 CMS1_k127_3999262_2 1197906.CAJQ02000006_gene2848 8.814e-171 554.0 COG1538@1|root,COG1538@2|Bacteria,1MWB0@1224|Proteobacteria,2TTSE@28211|Alphaproteobacteria,3JV4F@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria MU Outer membrane efflux protein - - - - - - - - - - - - OEP CMS1_k127_3999262_0 1429916.X566_16775 3.384e-253 786.0 COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,2TUTX@28211|Alphaproteobacteria,3JSM2@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria Q Multicopper oxidase - - 1.16.3.3 ko:K22348 - - - - ko00000,ko01000 - - - Cu-oxidase_2,Cu-oxidase_3 CMS1_k127_3999262_5 883078.HMPREF9695_01237 5.068e-64 223.0 COG4454@1|root,COG4454@2|Bacteria,1R91G@1224|Proteobacteria,2U6DH@28211|Alphaproteobacteria,3JVTM@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P Copper binding proteins, plastocyanin/azurin family copC - - - - - - - - - - - Copper-bind CMS1_k127_3999262_8 1197906.CAJQ02000027_gene1554 2.296e-26 113.0 COG5569@1|root,COG5569@2|Bacteria,1N8CJ@1224|Proteobacteria,2U9SU@28211|Alphaproteobacteria,3JZKA@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Copper binding periplasmic protein CusF - - - - - - - - - - - - CusF_Ec,DUF305 CMS1_k127_3999262_9 1187851.A33M_3863 1.453e-17 91.0 COG2010@1|root,COG2010@2|Bacteria 2|Bacteria C Cytochrome c - - - - - - - - - - - - Cytochrome_CBB3 CMS1_k127_3999262_7 1429916.X566_00305 4.725e-32 135.0 COG3038@1|root,COG3038@2|Bacteria,1NB7C@1224|Proteobacteria,2UGQW@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Prokaryotic cytochrome b561 - - - ko:K12262 - - - - ko00000 - - - Ni_hydr_CYTB CMS1_k127_3999262_11 1304878.AUGD01000014_gene3026 2.691e-05 50.0 COG2010@1|root,COG2010@2|Bacteria,1MZSK@1224|Proteobacteria,2UC5Q@28211|Alphaproteobacteria,3K0FX@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 CMS1_k127_3999262_4 1089551.KE386572_gene976 5.127e-75 253.0 COG3544@1|root,COG3544@2|Bacteria,1MVU8@1224|Proteobacteria,2TSBT@28211|Alphaproteobacteria,4BS60@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria S Domain of unknown function (DUF305) - - - - - - - - - - - - DUF305 CMS1_k127_3999262_1 392499.Swit_3062 3.341e-175 559.0 COG4638@1|root,COG4638@2|Bacteria,1MX47@1224|Proteobacteria,2TV03@28211|Alphaproteobacteria,2K0WS@204457|Sphingomonadales 204457|Sphingomonadales P Rieske (2Fe-2S) domain-containing protein ligX - - ko:K15060 ko00627,ko01120,map00627,map01120 - R09275 RC00392,RC01533 ko00000,ko00001 - - - Rieske CMS1_k127_4001656_1 663610.JQKO01000004_gene2843 1.213e-57 207.0 296ZZ@1|root,2ZU8H@2|Bacteria,1RED2@1224|Proteobacteria,2U6CK@28211|Alphaproteobacteria,3NCE0@45404|Beijerinckiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_4001656_2 717785.HYPMC_4521 2.68e-52 188.0 COG1671@1|root,COG1671@2|Bacteria,1RCZA@1224|Proteobacteria,2U997@28211|Alphaproteobacteria,3N6Z1@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria S Belongs to the UPF0178 family MA20_27470 - - ko:K09768 - - - - ko00000 - - - DUF188 CMS1_k127_4001656_3 1123355.JHYO01000018_gene1675 2.321e-38 148.0 2CKXE@1|root,32SD6@2|Bacteria,1N1MJ@1224|Proteobacteria,2UBTY@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_4001656_0 1144305.PMI02_04299 2.296e-219 683.0 COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,2TS6C@28211|Alphaproteobacteria,2K260@204457|Sphingomonadales 204457|Sphingomonadales K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth rpoD - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 CMS1_k127_40046_7 1187851.A33M_0645 1.513e-111 366.0 COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,2TUF7@28211|Alphaproteobacteria,3FE7Y@34008|Rhodovulum 28211|Alphaproteobacteria I CDP-alcohol phosphatidyltransferase pssA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.8.8 ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 M00093 R01800 RC00002,RC00017,RC02795 ko00000,ko00001,ko00002,ko01000 - - - CDP-OH_P_tran_2,CDP-OH_P_transf CMS1_k127_40046_10 1297865.APJD01000011_gene6825 1.238e-33 136.0 COG2371@1|root,COG2371@2|Bacteria,1MZQZ@1224|Proteobacteria,2TVBW@28211|Alphaproteobacteria,3JRXK@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly ureE - - ko:K03187 - - - - ko00000 - - - UreE_C,UreE_N CMS1_k127_40046_8 1187851.A33M_3426 7.007e-94 319.0 COG0625@1|root,COG0625@2|Bacteria,1REDI@1224|Proteobacteria,2TR9W@28211|Alphaproteobacteria,3FD5U@34008|Rhodovulum 28211|Alphaproteobacteria O Glutathione S-transferase, C-terminal domain MA20_04615 - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_C_2,GST_N,GST_N_3 CMS1_k127_40046_0 1429916.X566_04170 3.628e-283 876.0 COG1012@1|root,COG1012@2|Bacteria,1MUHV@1224|Proteobacteria,2TSMD@28211|Alphaproteobacteria,3JVCG@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Acyl-CoA reductase (LuxC) mmsA GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006950,GO:0006979,GO:0008150,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050896 1.2.1.18,1.2.1.27 ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 M00013 R00705,R00706,R00922,R00935 RC00004,RC02723,RC02817 ko00000,ko00001,ko00002,ko01000 - - - Aldedh CMS1_k127_40046_4 1429916.X566_18355 2.284e-134 431.0 COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,2TTXY@28211|Alphaproteobacteria,3JRM7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria N MotA/TolQ/ExbB proton channel family motA - - ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotA_ExbB CMS1_k127_40046_6 1187851.A33M_3429 7.105e-117 381.0 COG1360@1|root,COG1360@2|Bacteria,1MW1Y@1224|Proteobacteria,2TTW2@28211|Alphaproteobacteria,3FDIA@34008|Rhodovulum 28211|Alphaproteobacteria N Membrane MotB of proton-channel complex MotA/MotB motB - - ko:K02557 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - MotB_plug,OmpA CMS1_k127_40046_1 1187851.A33M_3433 4.99e-272 852.0 COG3158@1|root,COG3158@2|Bacteria,1MUVH@1224|Proteobacteria,2TRVJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Transport of potassium into the cell kup GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - ko:K03549 - - - - ko00000,ko02000 2.A.72 - - K_trans CMS1_k127_40046_9 883078.HMPREF9695_01319 7.055e-43 160.0 COG0607@1|root,COG0607@2|Bacteria,1N2R7@1224|Proteobacteria,2U9G7@28211|Alphaproteobacteria,3JZCR@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P Rhodanese Homology Domain MA20_26415 - - - - - - - - - - - Rhodanese CMS1_k127_40046_2 1245469.S58_29930 1.011e-164 528.0 COG0687@1|root,COG0687@2|Bacteria,1MUYW@1224|Proteobacteria,2TSUZ@28211|Alphaproteobacteria,3JUJ4@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P Required for the activity of the bacterial periplasmic transport system of putrescine potF - - ko:K11073 ko02010,map02010 M00300 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.2 - - SBP_bac_6,SBP_bac_8 CMS1_k127_40046_5 189753.AXAS01000016_gene1433 8.691e-123 400.0 COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,2TS2H@28211|Alphaproteobacteria,3JUSD@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M lipid A biosynthesis msbB - 2.3.1.241 ko:K02517 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Lip_A_acyltrans CMS1_k127_40046_3 1187851.A33M_2129 2.748e-140 449.0 COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,2TR1J@28211|Alphaproteobacteria,3FCNK@34008|Rhodovulum 28211|Alphaproteobacteria C Zinc-binding dehydrogenase - - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N,ADH_zinc_N_2 CMS1_k127_4021144_0 113395.AXAI01000009_gene2454 1.44e-171 559.0 COG0457@1|root,COG0457@2|Bacteria,1MUZK@1224|Proteobacteria,2TS0U@28211|Alphaproteobacteria,3JRSC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - - - - - - - - - - Glyco_transf_9,TPR_1,TPR_11,TPR_12,TPR_16,TPR_19,TPR_2,TPR_4,TPR_8 CMS1_k127_4021144_5 323097.Nham_3535 8.232e-65 228.0 COG0352@1|root,COG0352@2|Bacteria,1MV42@1224|Proteobacteria,2TSSA@28211|Alphaproteobacteria,3JS4M@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H Thiamine monophosphate synthase thiE - 2.5.1.3 ko:K00788 ko00730,ko01100,map00730,map01100 M00127 R03223,R10712 RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 - - - TMP-TENI CMS1_k127_4021144_3 1187851.A33M_1482 7.763e-105 352.0 COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2TR2B@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Sel1 domain protein repeat-containing protein - - - ko:K07126 - - - - ko00000 - - - Sel1 CMS1_k127_4021144_2 1187851.A33M_1481 5.45e-125 406.0 COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,2TR06@28211|Alphaproteobacteria,3FCZ2@34008|Rhodovulum 28211|Alphaproteobacteria G Inositol monophosphatase family suhB - 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P CMS1_k127_4021144_1 1429916.X566_12445 1.765e-136 441.0 COG1511@1|root,COG1511@2|Bacteria,1NYJB@1224|Proteobacteria,2TSX0@28211|Alphaproteobacteria,3JQXZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S MotA TolQ ExbB proton channel family MA20_18055 - - - - - - - - - - - MotA_ExbB CMS1_k127_4021144_4 1038859.AXAU01000012_gene4251 1.328e-83 282.0 COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,2TQKZ@28211|Alphaproteobacteria,3JQX8@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria N OmpA family MA20_18060 - - ko:K02557 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - OmpA CMS1_k127_402456_7 1429916.X566_13040 2.255e-65 231.0 2AP53@1|root,31E6R@2|Bacteria,1Q6T5@1224|Proteobacteria,2TVR4@28211|Alphaproteobacteria,3K72F@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_402456_1 1187851.A33M_2061 0.0 1134.0 COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,2TSYQ@28211|Alphaproteobacteria,3FCPT@34008|Rhodovulum 28211|Alphaproteobacteria O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins ftsH - - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41 CMS1_k127_402456_4 936455.KI421499_gene5520 3.909e-98 332.0 COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,2TRK1@28211|Alphaproteobacteria,3JS5P@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine tilS - 6.3.4.19 ko:K04075 - - R09597 RC02633,RC02634 ko00000,ko01000,ko03016 - - - ATP_bind_3 CMS1_k127_402456_5 1187851.A33M_2058 1.817e-82 287.0 COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,2U6ZQ@28211|Alphaproteobacteria,3FDG6@34008|Rhodovulum 28211|Alphaproteobacteria D Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division cpoB - - - - - - - - - - - TPR_16,TPR_6,TolA_bind_tri CMS1_k127_402456_0 670307.HYPDE_33583 0.0 1417.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria 28211|Alphaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family MA20_01135 - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran CMS1_k127_402456_3 443598.AUFA01000007_gene4478 6.907e-132 431.0 COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,2TU0W@28211|Alphaproteobacteria,3JRDK@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K03585 ko01501,ko01503,map01501,map01503 M00646,M00647,M00699,M00718 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 2.A.6.2,8.A.1.6 - - Biotin_lipoyl_2,HlyD_D23 CMS1_k127_402456_6 258594.RPA1123 6.534e-70 241.0 COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,2U758@28211|Alphaproteobacteria,3JUHJ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Belongs to the ompA family pal - - ko:K03640 - - - - ko00000,ko02000 2.C.1.2 - - OmpA CMS1_k127_402456_2 316055.RPE_4707 1.704e-223 700.0 COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,2TR03@28211|Alphaproteobacteria,3JTJA@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria U Involved in the TonB-independent uptake of proteins tolB - - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - PD40,TolB_N CMS1_k127_402456_8 1125973.JNLC01000013_gene3887 2.473e-25 107.0 COG3266@1|root,COG3266@2|Bacteria,1PZDQ@1224|Proteobacteria,2TWHN@28211|Alphaproteobacteria,3K6MQ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Cell division and transport-associated protein TolA tolA - - - - - - - - - - - - CMS1_k127_4030565_0 288000.BBta_p0205 7.475e-78 265.0 COG2801@1|root,COG2801@2|Bacteria,1MVN5@1224|Proteobacteria,2TQK0@28211|Alphaproteobacteria,3JZ81@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L Evidence Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - - - - - - - - - - HTH_21,rve_3 CMS1_k127_4030565_6 671143.DAMO_2594 5.561e-17 83.0 COG0745@1|root,COG0745@2|Bacteria 671143.DAMO_2594|- T phosphorelay signal transduction system - - - ko:K11443 ko02020,ko04112,map02020,map04112 M00511 - - ko00000,ko00001,ko00002,ko02022 - - - - CMS1_k127_4030565_2 1123258.AQXZ01000015_gene4550 2.236e-57 219.0 COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4FUZV@85025|Nocardiaceae 201174|Actinobacteria IQ synthetase - - - ko:K16029 ko01051,ko01052,map01051,map01052 - - - ko00000,ko00001 - - - AMP-binding,AMP-binding_C,Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH CMS1_k127_4030565_9 521003.COLINT_02830 0.0003874 48.0 COG0236@1|root,COG0236@2|Bacteria,2HAMZ@201174|Actinobacteria,4CWM1@84998|Coriobacteriia 84998|Coriobacteriia J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall dltC - 6.1.1.13 ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 M00725 R02718 RC00037,RC00094 ko00000,ko00001,ko00002,ko01000,ko01504 - - - PP-binding CMS1_k127_4030565_4 319003.Bra1253DRAFT_08264 1.539e-40 168.0 COG1696@1|root,COG1696@2|Bacteria,1R5WP@1224|Proteobacteria,2U7N8@28211|Alphaproteobacteria,3K3CQ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Membrane protein involved in D-alanine export - - - - - - - - - - - - - CMS1_k127_4030565_3 765911.Thivi_4065 1.798e-56 201.0 COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,1RPQF@1236|Gammaproteobacteria,1X2DV@135613|Chromatiales 135613|Chromatiales M Glycosyl transferases group 1 - - 2.4.1.346 ko:K13668 - - R11703,R11704 - ko00000,ko01000,ko01003 - GT4 - Glyco_transf_4,Glycos_transf_1 CMS1_k127_4030565_5 864051.BurJ1DRAFT_3207 2.059e-30 123.0 COG0399@1|root,COG0399@2|Bacteria,1MUMJ@1224|Proteobacteria,2VQRJ@28216|Betaproteobacteria 28216|Betaproteobacteria M Putative transposase - - - - - - - - - - - - Y2_Tnp,Zn_Tnp_IS91 CMS1_k127_4030565_8 666681.M301_0128 0.0001189 52.0 COG0582@1|root,COG0582@2|Bacteria,1QB64@1224|Proteobacteria,2VRP1@28216|Betaproteobacteria 28216|Betaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_integrase CMS1_k127_4030565_7 261292.Nit79A3_2441 3.089e-14 82.0 COG0582@1|root,COG0582@2|Bacteria,1QB64@1224|Proteobacteria,2VIGD@28216|Betaproteobacteria,373P0@32003|Nitrosomonadales 28216|Betaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_int_SAM_5,Phage_integrase CMS1_k127_4030565_1 1095769.CAHF01000022_gene372 5.632e-72 248.0 COG1285@1|root,COG1285@2|Bacteria,1MURJ@1224|Proteobacteria,2VNMB@28216|Betaproteobacteria,47374@75682|Oxalobacteraceae 28216|Betaproteobacteria S MgtC family - - - ko:K07507 - - - - ko00000,ko02000 9.B.20 - - MgtC CMS1_k127_4043483_3 1297863.APJF01000008_gene723 1.685e-123 401.0 COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,2TR5J@28211|Alphaproteobacteria,3JRXJ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L exodeoxyribonuclease III xth - 3.1.11.2 ko:K01142 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Exo_endo_phos CMS1_k127_4043483_4 1187851.A33M_2330 5.598e-114 381.0 COG0845@1|root,COG0845@2|Bacteria,1MW65@1224|Proteobacteria,2TV9W@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K07799 ko02020,map02020 M00648 - - ko00000,ko00001,ko00002,ko02000 8.A.1 - - Biotin_lipoyl_2,HlyD_D23 CMS1_k127_4043483_0 1187851.A33M_2329 0.0 1432.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria 28211|Alphaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family mdtC - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran CMS1_k127_4043483_5 258594.RPA2856 2.488e-49 178.0 COG0316@1|root,COG0316@2|Bacteria,1RHCW@1224|Proteobacteria,2UBR8@28211|Alphaproteobacteria,3JZKF@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Belongs to the HesB IscA family erpA - - ko:K13628,ko:K15724 - - - - ko00000,ko03016 - - - Fe-S_biosyn CMS1_k127_4043483_2 1197906.CAJQ02000011_gene625 1.448e-159 512.0 COG0232@1|root,COG0232@2|Bacteria,1MVQ2@1224|Proteobacteria,2TRCD@28211|Alphaproteobacteria,3JT2W@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria F Belongs to the dGTPase family. Type 2 subfamily dgt GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 ko:K01129 ko00230,map00230 - R01856 RC00017 ko00000,ko00001,ko01000 - - - HD,HD_assoc CMS1_k127_4043483_6 1123366.TH3_11155 3.965e-43 165.0 COG3247@1|root,COG3247@2|Bacteria,1R63F@1224|Proteobacteria,2U3AR@28211|Alphaproteobacteria,2JUM2@204441|Rhodospirillales 204441|Rhodospirillales S Short repeat of unknown function (DUF308) - - - - - - - - - - - - DUF308 CMS1_k127_4043483_1 1245469.S58_58300 1.151e-230 724.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,3JRKR@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria IQ AMP-binding enzyme C-terminal domain - - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C CMS1_k127_4043483_7 426117.M446_1919 2.949e-27 114.0 COG0028@1|root,COG0028@2|Bacteria,1MXDW@1224|Proteobacteria,2TT9X@28211|Alphaproteobacteria 28211|Alphaproteobacteria EH Belongs to the TPP enzyme family - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N CMS1_k127_4049636_7 1187851.A33M_2772 3.102e-37 143.0 COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,2TQRR@28211|Alphaproteobacteria,3FCFR@34008|Rhodovulum 28211|Alphaproteobacteria L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V CMS1_k127_4049636_2 450851.PHZ_c1270 9.487e-117 384.0 COG2040@1|root,COG2040@2|Bacteria,1MUXU@1224|Proteobacteria,2TURU@28211|Alphaproteobacteria,2KISH@204458|Caulobacterales 204458|Caulobacterales E Homocysteine S-methyltransferase - - - - - - - - - - - - S-methyl_trans CMS1_k127_4049636_3 1089552.KI911559_gene1689 1.374e-84 286.0 COG1309@1|root,COG1309@2|Bacteria,1RC7C@1224|Proteobacteria,2U5YR@28211|Alphaproteobacteria,2JSGT@204441|Rhodospirillales 204441|Rhodospirillales K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N CMS1_k127_4049636_6 335659.S23_68910 3.708e-40 163.0 2BKDV@1|root,32EUJ@2|Bacteria,1N9UU@1224|Proteobacteria,2TSMK@28211|Alphaproteobacteria,3JT65@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_4049636_5 318996.AXAZ01000010_gene5636 3.928e-66 235.0 2BKDV@1|root,32EUJ@2|Bacteria,1N9UU@1224|Proteobacteria,2TSMK@28211|Alphaproteobacteria,3JT65@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_4049636_4 716928.AJQT01000049_gene2011 4.874e-82 277.0 COG1765@1|root,COG1765@2|Bacteria,1R9XU@1224|Proteobacteria,2U6E4@28211|Alphaproteobacteria 28211|Alphaproteobacteria O PFAM OsmC family protein MA20_23315 - - - - - - - - - - - OsmC CMS1_k127_4049636_1 1380394.JADL01000003_gene4954 1.856e-139 451.0 COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,2TTMV@28211|Alphaproteobacteria,2JZJV@204441|Rhodospirillales 204441|Rhodospirillales S Alcohol dehydrogenase GroES-like domain - - 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N CMS1_k127_4049636_0 1038859.AXAU01000004_gene4558 0.0 1390.0 COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,2TSV0@28211|Alphaproteobacteria,3JV2M@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen glnD GO:0006355,GO:0006464,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008150,GO:0008152,GO:0009605,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0018175,GO:0018177,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:1901564,GO:1901698,GO:1901699,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 2.7.7.59 ko:K00990 ko02020,map02020 - - - ko00000,ko00001,ko01000 - - - ACT,GlnD_UR_UTase,GlnE,HD,NTP_transf_2 CMS1_k127_4052140_15 1187851.A33M_2087 4.331e-14 72.0 COG0670@1|root,COG0670@2|Bacteria,1MU69@1224|Proteobacteria,2TRSF@28211|Alphaproteobacteria,3FD0V@34008|Rhodovulum 28211|Alphaproteobacteria S Inhibitor of apoptosis-promoting Bax1 ybhL - - ko:K06890 - - - - ko00000 - - - Bax1-I CMS1_k127_4052140_13 1197906.CAJQ02000029_gene3902 7.144e-70 241.0 COG1247@1|root,COG1247@2|Bacteria,1RDHN@1224|Proteobacteria,2U98I@28211|Alphaproteobacteria,3JUN3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Acetyltransferase (GNAT) domain pat - 2.3.1.183 ko:K03823 ko00440,ko01130,map00440,map01130 - R08871,R08938 RC00004,RC00064 ko00000,ko00001,ko01000 - - - Acetyltransf_4 CMS1_k127_4052140_14 316056.RPC_0202 4.076e-47 174.0 2CCMQ@1|root,32RW3@2|Bacteria,1MZHB@1224|Proteobacteria,2UCC9@28211|Alphaproteobacteria,3JYQ9@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF2794) MA20_43795 - - - - - - - - - - - DUF2794 CMS1_k127_4052140_10 323098.Nwi_0324 8.958e-77 266.0 COG5429@1|root,COG5429@2|Bacteria,1MW6R@1224|Proteobacteria,2U33F@28211|Alphaproteobacteria,3JVYD@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF1223) MA20_43790 - - - - - - - - - - - DUF1223 CMS1_k127_4052140_0 1429916.X566_08275 0.0 1407.0 COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,2TT3T@28211|Alphaproteobacteria,3JQVB@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate acnA GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C CMS1_k127_4052140_11 1187851.A33M_2837 3.045e-73 253.0 COG4133@1|root,COG4133@2|Bacteria,1MZPC@1224|Proteobacteria,2TVBT@28211|Alphaproteobacteria,3FD7Z@34008|Rhodovulum 28211|Alphaproteobacteria O once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system ccmA - 3.6.3.41 ko:K02193 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.107 - - ABC_tran CMS1_k127_4052140_5 1187851.A33M_2838 7.62e-91 309.0 COG2386@1|root,COG2386@2|Bacteria,1NJB0@1224|Proteobacteria,2TUSG@28211|Alphaproteobacteria,3FD4B@34008|Rhodovulum 28211|Alphaproteobacteria U Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes ccmB GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016021,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - ko:K02194 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko02000 3.A.1.107 - - CcmB CMS1_k127_4052140_2 1037409.BJ6T_04380 5.438e-118 383.0 COG0755@1|root,COG0755@2|Bacteria,1MU61@1224|Proteobacteria,2TSW8@28211|Alphaproteobacteria,3JRN5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes ccmC GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748 - ko:K02195 ko02010,map02010 M00259 - - ko00000,ko00001,ko00002,ko02000 3.A.1.107 - - Cytochrom_C_asm CMS1_k127_4052140_16 652103.Rpdx1_0432 2.418e-06 58.0 2EIRC@1|root,33CGS@2|Bacteria,1N6T1@1224|Proteobacteria,2UFW2@28211|Alphaproteobacteria,3K0VT@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria U Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes ccmD - - ko:K02196 ko02010,map02010 - - - ko00000,ko00001,ko02000 3.A.1.107 - - CcmD CMS1_k127_4052140_7 1040989.AWZU01000036_gene7222 2.275e-80 275.0 COG0526@1|root,COG0526@2|Bacteria,1RI3N@1224|Proteobacteria,2TSEW@28211|Alphaproteobacteria,3JRPK@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria CO Redoxin ccmG GO:0005575,GO:0005623,GO:0042597,GO:0044464 - ko:K02199 - - - - ko00000,ko03110 - - - AhpC-TSA,Redoxin CMS1_k127_4052140_6 391735.Veis_0690 1.283e-84 293.0 COG1835@1|root,COG1835@2|Bacteria,1PD3F@1224|Proteobacteria,2VTV6@28216|Betaproteobacteria,4AEXD@80864|Comamonadaceae 28216|Betaproteobacteria I Acyltransferase family - - - - - - - - - - - - Acyl_transf_3 CMS1_k127_4052140_12 1120956.JHZK01000005_gene2264 5.048e-72 247.0 COG2917@1|root,COG2917@2|Bacteria,1NWIZ@1224|Proteobacteria,2U74X@28211|Alphaproteobacteria,1JNZI@119043|Rhodobiaceae 28211|Alphaproteobacteria D probably involved in intracellular septation ispZ - - ko:K06190 - - - - ko00000 - - - IspA CMS1_k127_4052140_1 1211115.ALIQ01000212_gene3264 1.96e-132 428.0 COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,2TS0M@28211|Alphaproteobacteria,3NA9D@45404|Beijerinckiaceae 28211|Alphaproteobacteria U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components ftsY - - ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 - - SRP54,SRP54_N CMS1_k127_4052140_4 666684.AfiDRAFT_1407 8.456e-116 377.0 COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,2TSCG@28211|Alphaproteobacteria,3JRTQ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Pseudouridine synthase MA20_43745 - 5.4.99.28,5.4.99.29 ko:K06177 - - - - ko00000,ko01000,ko03009,ko03016 - - - PseudoU_synth_2 CMS1_k127_4052140_9 670307.HYPDE_27243 8.935e-79 273.0 COG0500@1|root,COG2226@2|Bacteria,1MYPU@1224|Proteobacteria,2UD81@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Methyltransferase domain - - - - - - - - - - - - - CMS1_k127_4052140_8 1392838.AWNM01000049_gene2098 5.427e-80 272.0 COG3576@1|root,COG3576@2|Bacteria,1MWG9@1224|Proteobacteria,2VQ6P@28216|Betaproteobacteria,3T5FN@506|Alcaligenaceae 28216|Betaproteobacteria S Pyridoxamine 5'-phosphate oxidase - - - ko:K07006 - - - - ko00000 - - - Putative_PNPOx CMS1_k127_4052140_3 1411123.JQNH01000001_gene3759 3.935e-116 378.0 COG0621@1|root,COG0621@2|Bacteria,1MUCS@1224|Proteobacteria,2TRYD@28211|Alphaproteobacteria 28211|Alphaproteobacteria J MiaB-like tRNA modifying enzyme mtaB GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360 2.8.4.5 ko:K18707 - - R10649 RC00003,RC03221 ko00000,ko01000,ko03016 - - - Radical_SAM,UPF0004 CMS1_k127_4065804_1 172088.AUGA01000021_gene5274 3.868e-46 171.0 COG2128@1|root,COG2128@2|Bacteria,1N1YR@1224|Proteobacteria,2UENK@28211|Alphaproteobacteria,3K2S2@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - - - - - - - - - - - CMS1_k127_4065804_0 1038859.AXAU01000011_gene2468 6.052e-92 310.0 COG1595@1|root,COG1595@2|Bacteria,1MXVA@1224|Proteobacteria,2TV85@28211|Alphaproteobacteria,3JR9S@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 CMS1_k127_4065804_2 526226.Gbro_0287 1.205e-24 105.0 COG0640@1|root,COG0640@2|Bacteria,2IKQY@201174|Actinobacteria 201174|Actinobacteria K arsR family - - - - - - - - - - - - HTH_20 CMS1_k127_4085365_0 1429916.X566_08400 1.446e-74 251.0 COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,2TR6K@28211|Alphaproteobacteria,3JUMY@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuC - 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase CMS1_k127_4085365_5 1036674.A28LD_1830 8.513e-12 73.0 291GD@1|root,2ZP33@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - CMS1_k127_4085365_6 316056.RPC_0228 9.186e-06 53.0 29BSY@1|root,2ZYRA@2|Bacteria,1RKPZ@1224|Proteobacteria,2UA1S@28211|Alphaproteobacteria,3JZFM@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_4085365_2 1187851.A33M_3740 1.831e-62 217.0 COG3824@1|root,COG3824@2|Bacteria,1N18M@1224|Proteobacteria,2UBUK@28211|Alphaproteobacteria,3FEFF@34008|Rhodovulum 28211|Alphaproteobacteria S Zincin-like metallopeptidase MA20_43655 - 2.7.2.8 ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R02649 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - Zincin_1 CMS1_k127_4085365_4 1116369.KB890024_gene651 8.674e-37 144.0 COG3791@1|root,COG3791@2|Bacteria,1RBIH@1224|Proteobacteria,2U5D0@28211|Alphaproteobacteria,43KSG@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Glutathione-dependent formaldehyde-activating enzyme - - - - - - - - - - - - GFA CMS1_k127_4085365_3 1320556.AVBP01000007_gene538 7e-43 161.0 COG3791@1|root,COG3791@2|Bacteria,1RBIH@1224|Proteobacteria,2U5D0@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Glutathione-dependent formaldehyde-activating - - - - - - - - - - - - GFA CMS1_k127_4085365_1 1380355.JNIJ01000057_gene205 1.273e-63 219.0 COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,2TRRS@28211|Alphaproteobacteria,3JS0A@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuD - 4.2.1.33,4.2.1.35 ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R10170 RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase_C CMS1_k127_4087630_0 652103.Rpdx1_4170 4.359e-167 527.0 COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,2TR3W@28211|Alphaproteobacteria,3JU8E@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria F Belongs to the CarA family carA GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_sm_chain,GATase CMS1_k127_4087630_1 1187851.A33M_4274 2.383e-62 220.0 COG4297@1|root,COG4297@2|Bacteria,1RB1W@1224|Proteobacteria,2U14J@28211|Alphaproteobacteria 28211|Alphaproteobacteria S protein containing double-stranded beta helix domain - - - - - - - - - - - - Cupin_1,Cupin_2,Cupin_6 CMS1_k127_4087630_2 1038862.KB893906_gene5280 4.606e-22 97.0 COG1295@1|root,COG1295@2|Bacteria,1MXQA@1224|Proteobacteria,2TSFP@28211|Alphaproteobacteria,3JS43@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Virulence factor BrkB - - - ko:K07058 - - - - ko00000 - - - Virul_fac_BrkB CMS1_k127_4100809_0 709797.CSIRO_1847 1.138e-261 811.0 COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,2TRDD@28211|Alphaproteobacteria,3JSDV@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) dxs - 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 - - - DXP_synthase_N,Transket_pyr,Transketolase_C CMS1_k127_4100809_5 420324.KI912026_gene5009 1.326e-77 266.0 COG1189@1|root,COG1189@2|Bacteria,1MWP5@1224|Proteobacteria,2TRW9@28211|Alphaproteobacteria,1JTJK@119045|Methylobacteriaceae 28211|Alphaproteobacteria J PFAM ribosomal RNA methyltransferase RrmJ FtsJ tlyA - 2.1.1.226,2.1.1.227 ko:K06442 - - - - ko00000,ko01000,ko03009 - - - FtsJ,S4 CMS1_k127_4100809_3 652103.Rpdx1_1111 7.123e-162 520.0 COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,2TR40@28211|Alphaproteobacteria,3JT5J@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family rumA - 2.1.1.190,2.1.1.35 ko:K00557,ko:K03215 - - - - ko00000,ko01000,ko03009,ko03016 - - - tRNA_U5-meth_tr CMS1_k127_4100809_4 1038858.AXBA01000002_gene3933 5.479e-98 329.0 COG2304@1|root,COG2304@2|Bacteria,1PH4N@1224|Proteobacteria,2TQTJ@28211|Alphaproteobacteria,3EYXS@335928|Xanthobacteraceae 28211|Alphaproteobacteria S Protein of unknown function (DUF1194) MA20_07505 - - - - - - - - - - - DUF1194 CMS1_k127_4100809_2 1187851.A33M_0487 4.626e-175 558.0 COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,2TSMA@28211|Alphaproteobacteria,3FD1V@34008|Rhodovulum 28211|Alphaproteobacteria H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate ribB - 3.5.4.25,4.1.99.12 ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 M00125,M00840 R00425,R07281 RC00293,RC01792,RC01815,RC02504 ko00000,ko00001,ko00002,ko01000 - - - DHBP_synthase,GTP_cyclohydro2 CMS1_k127_4100809_1 1411123.JQNH01000001_gene498 1.561e-185 583.0 COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,2TQY2@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system aroC GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 - - - Chorismate_synt CMS1_k127_4145926_1 367336.OM2255_13409 3.349e-96 316.0 COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,2TQXD@28211|Alphaproteobacteria 28211|Alphaproteobacteria E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit hisF GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth CMS1_k127_4145926_0 1415756.JQMY01000001_gene2039 8.676e-127 408.0 COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,2TRSG@28211|Alphaproteobacteria,2PCAZ@252301|Oceanicola 28211|Alphaproteobacteria E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase hisA GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04640 RC00945 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth CMS1_k127_4175084_9 420324.KI912067_gene6546 3.266e-28 113.0 COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,2TQJ7@28211|Alphaproteobacteria,1JSVV@119045|Methylobacteriaceae 28211|Alphaproteobacteria P Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity katG GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 ko:K03782 ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110 - R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906 RC00034,RC00213,RC00767,RC02141 ko00000,ko00001,ko01000 - - - peroxidase CMS1_k127_4175084_2 323098.Nwi_0032 1.124e-141 453.0 COG0623@1|root,COG0623@2|Bacteria,1MV05@1224|Proteobacteria,2TSU4@28211|Alphaproteobacteria,3JS6H@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Enoyl- acyl-carrier-protein reductase NADH fabI GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901576 1.3.1.10,1.3.1.9 ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 M00083,M00572 R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671 RC00052,RC00076,RC00120 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 CMS1_k127_4175084_0 1211115.ALIQ01000170_gene4039 1.069e-226 707.0 COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,2TQYV@28211|Alphaproteobacteria,3N9WM@45404|Beijerinckiaceae 28211|Alphaproteobacteria IQ Beta-ketoacyl synthase, C-terminal domain fabB GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.41 ko:K00647 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt CMS1_k127_4175084_4 438753.AZC_4642 3.179e-96 322.0 COG0764@1|root,COG0764@2|Bacteria,1MWV8@1224|Proteobacteria,2TV8S@28211|Alphaproteobacteria,3EYRH@335928|Xanthobacteraceae 28211|Alphaproteobacteria I Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length fabA - 4.2.1.59,5.3.3.14 ko:K01716 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00083 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07639 RC00831,RC01078,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FabA CMS1_k127_4175084_8 1187851.A33M_0197 4.639e-65 232.0 COG0735@1|root,COG0735@2|Bacteria,1RH58@1224|Proteobacteria,2U75R@28211|Alphaproteobacteria,3FDAW@34008|Rhodovulum 28211|Alphaproteobacteria K Ferric uptake regulator family MA20_24005 - - ko:K09826 - - - - ko00000,ko03000 - - - FUR CMS1_k127_4175084_7 709797.CSIRO_1117 2.258e-65 228.0 COG3807@1|root,COG3807@2|Bacteria,1RHM2@1224|Proteobacteria,2UA1R@28211|Alphaproteobacteria,3JT0T@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Bacterial SH3 domain MA20_24010 - 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - SH3_4 CMS1_k127_4175084_1 1131814.JAFO01000001_gene2350 3.978e-178 562.0 COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,2TSM8@28211|Alphaproteobacteria,3EYA2@335928|Xanthobacteraceae 28211|Alphaproteobacteria CH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain gyaR GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.26 ko:K00015 ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120 - R00717,R01388 RC00031,RC00042 ko00000,ko00001,ko01000 - - - 2-Hacid_dh,2-Hacid_dh_C CMS1_k127_4175084_3 1187851.A33M_1473 3.479e-130 421.0 COG0476@1|root,COG0476@2|Bacteria,1MW7H@1224|Proteobacteria,2TRWY@28211|Alphaproteobacteria,3FCZR@34008|Rhodovulum 28211|Alphaproteobacteria H ThiF family moeB - 2.7.7.80 ko:K21029 ko04122,map04122 - R07459 RC00043 ko00000,ko00001,ko01000 - - - ThiF CMS1_k127_4175084_6 1429916.X566_08420 6.293e-83 295.0 COG0265@1|root,COG3409@1|root,COG0265@2|Bacteria,COG3409@2|Bacteria,1MV63@1224|Proteobacteria,2TU13@28211|Alphaproteobacteria,3JUXT@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria MO Putative peptidoglycan binding domain - - - - - - - - - - - - PG_binding_1,SPOR,Trypsin_2 CMS1_k127_4175084_5 622637.KE124774_gene4122 6.436e-90 300.0 COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,2TRYS@28211|Alphaproteobacteria,36XEH@31993|Methylocystaceae 28211|Alphaproteobacteria I Enoyl-CoA hydratase/isomerase paaF - 4.2.1.17 ko:K01692 ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212 M00032,M00087 R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093 RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 CMS1_k127_4188006_2 323097.Nham_1133 5.283e-96 332.0 COG2845@1|root,COG2845@2|Bacteria,1R4X7@1224|Proteobacteria,2U5AU@28211|Alphaproteobacteria,3JRNF@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF459) - - - ko:K09795 - - - - ko00000 - - - DUF459 CMS1_k127_4188006_0 1187851.A33M_3433 3.233e-262 822.0 COG3158@1|root,COG3158@2|Bacteria,1MUVH@1224|Proteobacteria,2TRVJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Transport of potassium into the cell kup GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - ko:K03549 - - - - ko00000,ko02000 2.A.72 - - K_trans CMS1_k127_4188006_1 981384.AEYW01000022_gene3737 2.004e-134 438.0 COG3000@1|root,COG3000@2|Bacteria,1MW5G@1224|Proteobacteria,2TU63@28211|Alphaproteobacteria,4NBW6@97050|Ruegeria 28211|Alphaproteobacteria I Fatty acid hydroxylase superfamily - - - - - - - - - - - - FA_hydroxylase CMS1_k127_4195352_15 639283.Snov_3911 8.619e-71 243.0 COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,2TQZP@28211|Alphaproteobacteria,3EYAX@335928|Xanthobacteraceae 28211|Alphaproteobacteria OU Serine dehydrogenase proteinase sohB - - ko:K04773,ko:K04774 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49 CMS1_k127_4195352_16 114615.BRADO2025 3.564e-68 241.0 COG4123@1|root,COG4123@2|Bacteria,1MXEQ@1224|Proteobacteria,2TUBR@28211|Alphaproteobacteria,3JWJT@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Methyltransferase small domain yfiC - 2.1.1.223 ko:K15460 - - - - ko00000,ko01000,ko03016 - - - MTS CMS1_k127_4195352_19 652103.Rpdx1_1205 1.06e-27 117.0 2E3KZ@1|root,32YJ8@2|Bacteria,1N7A7@1224|Proteobacteria,2UFMR@28211|Alphaproteobacteria,3K0FM@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Putative prokaryotic signal transducing protein MA20_42240 - - - - - - - - - - - DUF2007 CMS1_k127_4195352_6 1038860.AXAP01000051_gene5427 4.351e-167 530.0 COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,2TSDZ@28211|Alphaproteobacteria,3JRJF@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H Belongs to the FPP GGPP synthase family ispB GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663 2.5.1.90 ko:K02523 ko00900,ko01110,map00900,map01110 - R09248 RC00279 ko00000,ko00001,ko01000,ko01006 - - - polyprenyl_synt CMS1_k127_4195352_13 1187851.A33M_2188 2.386e-85 292.0 COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,2TUFV@28211|Alphaproteobacteria,3FD4N@34008|Rhodovulum 28211|Alphaproteobacteria F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol ispE GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 ko:K00919 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05634 RC00002,RC01439 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N CMS1_k127_4195352_1 652103.Rpdx1_1202 8.951e-223 711.0 COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,2TQV5@28211|Alphaproteobacteria,3JTV2@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Tetratricopeptide repeat MA20_42300 - - - - - - - - - - - TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8 CMS1_k127_4195352_0 1187851.A33M_3570 2.405e-287 890.0 COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,1MVU6@1224|Proteobacteria,2TS0R@28211|Alphaproteobacteria,3FCV7@34008|Rhodovulum 28211|Alphaproteobacteria C Thi4 family etf GO:0003674,GO:0003824,GO:0004174,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016645,GO:0016649,GO:0016722,GO:0017133,GO:0019866,GO:0022900,GO:0022904,GO:0031090,GO:0031224,GO:0031300,GO:0031301,GO:0031304,GO:0031305,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032592,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043783,GO:0044237,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045251,GO:0045333,GO:0048037,GO:0048038,GO:0048039,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070013,GO:0098573,GO:0098798,GO:1902494,GO:1990204 1.5.5.1 ko:K00311 - - - - ko00000,ko01000 - - - ETF_QO,FAD_binding_2,NAD_binding_8,Thi4 CMS1_k127_4195352_14 1089551.KE386572_gene4771 7.917e-72 246.0 COG1225@1|root,COG1225@2|Bacteria,1RA5K@1224|Proteobacteria,2U6EF@28211|Alphaproteobacteria,4BS6D@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria O Redoxin - - - - - - - - - - - - AhpC-TSA CMS1_k127_4195352_9 1125973.JNLC01000014_gene2624 7.582e-115 376.0 COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,2TT4Q@28211|Alphaproteobacteria,3JU3F@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L UreE urease accessory protein, C-terminal domain udgA - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG CMS1_k127_4195352_20 324602.Caur_2180 2.833e-18 90.0 COG1917@1|root,COG1917@2|Bacteria 2|Bacteria L Cupin 2, conserved barrel domain protein - - - - - - - - - - - - Cupin_2 CMS1_k127_4195352_3 1187851.A33M_4294 7.579e-202 637.0 COG2252@1|root,COG2252@2|Bacteria,1MUV0@1224|Proteobacteria,2TRC0@28211|Alphaproteobacteria 28211|Alphaproteobacteria S PFAM Xanthine uracil vitamin C permease purP - - ko:K06901 - - - - ko00000,ko02000 2.A.1.40 - - Xan_ur_permease CMS1_k127_4195352_4 1187851.A33M_4296 1.625e-198 629.0 COG1271@1|root,COG1271@2|Bacteria,1MV60@1224|Proteobacteria,2TQMA@28211|Alphaproteobacteria,3FCSV@34008|Rhodovulum 28211|Alphaproteobacteria C Cytochrome bd terminal oxidase subunit I - - 1.10.3.14 ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - Cyt_bd_oxida_I CMS1_k127_4195352_7 1131814.JAFO01000001_gene3379 1.659e-156 501.0 COG1294@1|root,COG1294@2|Bacteria,1MURP@1224|Proteobacteria,2TU3I@28211|Alphaproteobacteria,3EYKY@335928|Xanthobacteraceae 28211|Alphaproteobacteria C Cytochrome bd terminal oxidase subunit II - - 1.10.3.14 ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - Cyt_bd_oxida_II CMS1_k127_4195352_8 1187851.A33M_4298 6.241e-145 475.0 COG1807@1|root,COG1807@2|Bacteria,1QA8B@1224|Proteobacteria,2TY1E@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Dolichyl-phosphate-mannose-protein mannosyltransferase MA20_42315 - - - - - - - - - - - PMT_2 CMS1_k127_4195352_12 1187851.A33M_4299 3.127e-97 323.0 COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,2U73X@28211|Alphaproteobacteria,3FD3U@34008|Rhodovulum 28211|Alphaproteobacteria L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_HII CMS1_k127_4195352_2 1205680.CAKO01000002_gene2525 1.673e-203 645.0 COG2114@1|root,COG2114@2|Bacteria,1NAJG@1224|Proteobacteria,2TSVT@28211|Alphaproteobacteria,2JUSX@204441|Rhodospirillales 204441|Rhodospirillales T Adenylyl- / guanylyl cyclase, catalytic domain - - - - - - - - - - - - Guanylate_cyc CMS1_k127_4195352_17 1244869.H261_00235 1.187e-38 150.0 COG0346@1|root,COG0346@2|Bacteria,1N116@1224|Proteobacteria,2UC5P@28211|Alphaproteobacteria,2JTFT@204441|Rhodospirillales 204441|Rhodospirillales E COG0346 Lactoylglutathione lyase and related lyases - - - ko:K07032 - - - - ko00000 - - - Glyoxalase CMS1_k127_4195352_5 936455.KI421499_gene4817 1.274e-186 589.0 COG1533@1|root,COG1533@2|Bacteria,1MW0H@1224|Proteobacteria,2TQQB@28211|Alphaproteobacteria,3JSMU@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L Elongator protein 3, MiaB family, Radical SAM MA20_42330 - - - - - - - - - - - Radical_SAM CMS1_k127_4195352_18 1187851.A33M_4301 7.046e-38 149.0 COG1216@1|root,COG1216@2|Bacteria,1N6DH@1224|Proteobacteria,2TWBP@28211|Alphaproteobacteria 28211|Alphaproteobacteria S COG0463 Glycosyltransferases involved in cell wall biogenesis - - - - - - - - - - - - Glycos_transf_2 CMS1_k127_4195352_11 1173024.KI912149_gene6263 5.135e-100 335.0 COG0454@1|root,COG1846@1|root,COG0456@2|Bacteria,COG1846@2|Bacteria,1GKR9@1117|Cyanobacteria,1JMKR@1189|Stigonemataceae 1117|Cyanobacteria K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 CMS1_k127_4195352_10 384765.SIAM614_28462 2.827e-111 370.0 COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,2TVFM@28211|Alphaproteobacteria 28211|Alphaproteobacteria J exonuclease of the beta-lactamase fold involved in RNA processing - - - ko:K07576 - - - - ko00000 - - - Beta-Casp,Lactamase_B,RMMBL CMS1_k127_4201185_0 290400.Jann_0056 2.567e-16 80.0 COG1485@1|root,COG1485@2|Bacteria,1MUUW@1224|Proteobacteria,2TRG1@28211|Alphaproteobacteria 28211|Alphaproteobacteria E ATPase, AFG1 family zapE GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0006091,GO:0006119,GO:0006123,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007005,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016310,GO:0017144,GO:0019538,GO:0019637,GO:0019646,GO:0019693,GO:0022900,GO:0022904,GO:0030163,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0035694,GO:0042773,GO:0042775,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071840,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901565,GO:1901575 - ko:K06916 - - - - ko00000,ko03036 - - - AFG1_ATPase CMS1_k127_4201185_1 570967.JMLV01000012_gene3218 7.847e-09 58.0 COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,2TSV6@28211|Alphaproteobacteria,2JPAI@204441|Rhodospirillales 204441|Rhodospirillales C Catalyzes the reversible oxidation of malate to oxaloacetate mdh - 1.1.1.37 ko:K00024 ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740 R00342,R07136 RC00031 ko00000,ko00001,ko00002,ko01000 - - - Ldh_1_C,Ldh_1_N CMS1_k127_4228534_0 1452718.JBOY01000084_gene2664 3.656e-106 349.0 COG3288@1|root,COG3288@2|Bacteria,1MVXU@1224|Proteobacteria,1RN23@1236|Gammaproteobacteria 1236|Gammaproteobacteria C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane pntAA - 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N CMS1_k127_4228534_2 1266925.JHVX01000013_gene1611 1.05e-37 145.0 COG3288@1|root,COG3288@2|Bacteria,1MZ3E@1224|Proteobacteria,2VSM2@28216|Betaproteobacteria,373AX@32003|Nitrosomonadales 28216|Betaproteobacteria C 4TM region of pyridine nucleotide transhydrogenase, mitoch pntAb - 1.6.1.1,1.6.1.2 ko:K00322,ko:K00324 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - PNTB_4TM CMS1_k127_4228534_1 1288494.EBAPG3_22020 1.547e-73 253.0 COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,2VIDR@28216|Betaproteobacteria,372C8@32003|Nitrosomonadales 28216|Betaproteobacteria C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane pntB - 1.6.1.2 ko:K00325 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - PNTB CMS1_k127_4231658_1 1120956.JHZK01000009_gene1717 5.959e-95 325.0 COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria 1224|Proteobacteria M Glycosyl transferase group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 CMS1_k127_4231658_3 1280679.ATVX01000003_gene3079 8.888e-16 87.0 COG0500@1|root,COG2226@2|Bacteria 2|Bacteria Q methyltransferase - - - - - - - - - - - - Methyltransf_11 CMS1_k127_4231658_2 755178.Cyan10605_1081 3.163e-38 153.0 COG0500@1|root,COG2226@2|Bacteria,1GAPB@1117|Cyanobacteria 1117|Cyanobacteria Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_11 CMS1_k127_4231658_0 1122135.KB893134_gene3944 6.381e-121 397.0 COG0438@1|root,COG0438@2|Bacteria,1N0DG@1224|Proteobacteria,2U4R4@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Glycosyl transferase 4-like - - - - - - - - - - - - Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 CMS1_k127_4273278_1 335659.S23_54440 2.42e-55 194.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,2TR3C@28211|Alphaproteobacteria,3JSHW@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G pyruvate phosphate dikinase ppdK - 2.7.9.1 ko:K01006 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 M00169,M00171,M00172,M00173 R00206 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PEP-utilizers_C,PPDK_N CMS1_k127_4273278_0 991905.SL003B_3742 1.122e-59 224.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2TQQE@28211|Alphaproteobacteria,4BRDM@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - MCPsignal CMS1_k127_4273278_2 1197906.CAJQ02000023_gene2614 3.111e-10 64.0 COG3773@1|root,COG3773@2|Bacteria,1MWX3@1224|Proteobacteria,2TT15@28211|Alphaproteobacteria,3JT5Q@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Cell Wall Hydrolase sleB - - - - - - - - - - - Hydrolase_2 CMS1_k127_4277741_2 1510531.JQJJ01000012_gene1764 1.194e-05 55.0 COG0346@1|root,COG0346@2|Bacteria,1RB65@1224|Proteobacteria,2U7DP@28211|Alphaproteobacteria,3JYA1@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily MA20_35640 - - - - - - - - - - - Glyoxalase CMS1_k127_4277741_1 1298867.AUES01000010_gene5864 7.289e-144 467.0 COG1149@1|root,COG1149@2|Bacteria,1QTYV@1224|Proteobacteria,2TTH3@28211|Alphaproteobacteria,3JV8K@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C TIGRFAM CitB domain protein tcuB - - ko:K13795 - - - - ko00000 - - - - CMS1_k127_4277741_0 1121033.AUCF01000014_gene1335 3.351e-168 533.0 COG1053@1|root,COG1053@2|Bacteria,1MX5A@1224|Proteobacteria,2TV7T@28211|Alphaproteobacteria,2JPPK@204441|Rhodospirillales 204441|Rhodospirillales C FAD dependent oxidoreductase - - - ko:K13796 - - - - ko00000 - - - FAD_binding_2 CMS1_k127_4293108_0 1187851.A33M_1030 1.994e-105 348.0 COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,2TUG7@28211|Alphaproteobacteria,3FD3G@34008|Rhodovulum 28211|Alphaproteobacteria J RNA 2'-O ribose methyltransferase substrate binding rlmB - 2.1.1.185 ko:K03218 - - - - ko00000,ko01000,ko03009 - - - SpoU_methylase,SpoU_sub_bind CMS1_k127_4307187_1 1187851.A33M_4433 1.281e-145 466.0 COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,2TQPB@28211|Alphaproteobacteria,3FCKV@34008|Rhodovulum 28211|Alphaproteobacteria E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine lysA GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC CMS1_k127_4307187_0 1187851.A33M_4436 8.494e-298 936.0 COG0419@1|root,COG0419@2|Bacteria,1MWCT@1224|Proteobacteria,2TS61@28211|Alphaproteobacteria,3FCMF@34008|Rhodovulum 28211|Alphaproteobacteria L Domain of unknown function (DUF4175) - - - - - - - - - - - - DUF4175 CMS1_k127_4307187_8 288000.BBta_1175 2.807e-42 168.0 2E521@1|root,32ZVA@2|Bacteria,1N9PP@1224|Proteobacteria,2UG1E@28211|Alphaproteobacteria,3JVB9@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S TIGRFAM MJ0042 family finger-like protein - - - - - - - - - - - - DUF3426,zinc_ribbon_4 CMS1_k127_4307187_2 1187851.A33M_4412 3.216e-123 397.0 COG2884@1|root,COG2884@2|Bacteria,1MVQ4@1224|Proteobacteria,2TS9Y@28211|Alphaproteobacteria,3FD0X@34008|Rhodovulum 28211|Alphaproteobacteria D ATPases associated with a variety of cellular activities ftsE - - ko:K09812 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - ABC_tran CMS1_k127_4307187_3 316055.RPE_4831 6.403e-97 327.0 COG2177@1|root,COG2177@2|Bacteria,1MXKQ@1224|Proteobacteria,2TSNT@28211|Alphaproteobacteria,3JUMC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria D Cell division protein ftsX - - ko:K09811 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - - CMS1_k127_4307187_6 1187851.A33M_4410 5.919e-58 207.0 COG1434@1|root,COG1434@2|Bacteria,1RHMV@1224|Proteobacteria,2U957@28211|Alphaproteobacteria 28211|Alphaproteobacteria S DUF218 domain MA20_20455 - - - - - - - - - - - DUF218 CMS1_k127_4307187_4 1411123.JQNH01000001_gene3558 2.036e-86 296.0 COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,2TT3P@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Acyl-transferase plsC - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase CMS1_k127_4307187_5 1040989.AWZU01000001_gene5576 3.875e-80 273.0 COG3703@1|root,COG3703@2|Bacteria,1QA7D@1224|Proteobacteria,2U7C6@28211|Alphaproteobacteria,3JSG9@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides chaC - - ko:K07232 - - - - ko00000 - - - ChaC CMS1_k127_4307187_7 1380355.JNIJ01000042_gene5122 2.907e-43 164.0 COG4093@1|root,COG4093@2|Bacteria,1MXJA@1224|Proteobacteria,2TRH7@28211|Alphaproteobacteria,3JTXX@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Uncharacterized protein conserved in bacteria (DUF2125) MA20_20440 - - - - - - - - - - - DUF2125 CMS1_k127_4310676_1 1038867.AXAY01000001_gene6569 2.79e-79 271.0 COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2TRYI@28211|Alphaproteobacteria,3JT3S@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C FAD linked oxidases, C-terminal domain MA20_42035 GO:0000166,GO:0003674,GO:0003824,GO:0004457,GO:0004458,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006089,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016053,GO:0016491,GO:0016614,GO:0016898,GO:0019249,GO:0019516,GO:0019752,GO:0022900,GO:0022904,GO:0030447,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046394,GO:0048037,GO:0050660,GO:0050662,GO:0051990,GO:0055114,GO:0071704,GO:0071949,GO:0072330,GO:0097159,GO:0099615,GO:1901265,GO:1901363,GO:1901576,GO:1901615,GO:1901617 1.1.2.4 ko:K00102 ko00620,map00620 - R00197 RC00044 ko00000,ko00001,ko01000 - - - FAD-oxidase_C,FAD_binding_4 CMS1_k127_4310676_0 1245469.S58_54680 5.933e-126 410.0 COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,2TRIM@28211|Alphaproteobacteria,3JU6E@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine sua5 GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 ko:K07566 - - R10463 RC00745 ko00000,ko01000,ko03009,ko03016 - - - SUA5,Sua5_yciO_yrdC CMS1_k127_4310676_2 87626.PTD2_17885 3.55e-05 51.0 2DR6A@1|root,33ACN@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - CMS1_k127_4325627_4 1297863.APJF01000029_gene1438 1.323e-57 209.0 COG4961@1|root,COG4961@2|Bacteria,1MWXU@1224|Proteobacteria,2TRQP@28211|Alphaproteobacteria,3JSKJ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria U Putative Flp pilus-assembly TadE/G-like - - - - - - - - - - - - Tad,VWA CMS1_k127_4325627_5 1187851.A33M_2727 1.1e-55 200.0 COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,2U982@28211|Alphaproteobacteria,3FDAX@34008|Rhodovulum 28211|Alphaproteobacteria S Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation clpS - - ko:K06891 - - - - ko00000 - - - ClpS CMS1_k127_4325627_0 639283.Snov_1496 0.0 1367.0 COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,2TQUZ@28211|Alphaproteobacteria,3EZ3T@335928|Xanthobacteraceae 28211|Alphaproteobacteria O C-terminal, D2-small domain, of ClpB protein clpA GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043335,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 - ko:K03694 - - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N CMS1_k127_4325627_1 1187851.A33M_2730 2.704e-72 251.0 COG1296@1|root,COG1296@2|Bacteria,1QFIN@1224|Proteobacteria,2U0SX@28211|Alphaproteobacteria 28211|Alphaproteobacteria E PFAM AzlC family protein MA20_36175 - - - - - - - - - - - AzlC CMS1_k127_4325627_3 1187851.A33M_2730 3.81e-59 221.0 COG1296@1|root,COG1296@2|Bacteria,1QFIN@1224|Proteobacteria,2U0SX@28211|Alphaproteobacteria 28211|Alphaproteobacteria E PFAM AzlC family protein MA20_36175 - - - - - - - - - - - AzlC CMS1_k127_4325627_6 1187851.A33M_2731 6.355e-30 132.0 2E5FD@1|root,33072@2|Bacteria,1NBEM@1224|Proteobacteria,2UGG8@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Branched-chain amino acid transport - - - - - - - - - - - - AzlD CMS1_k127_4325627_2 1131814.JAFO01000001_gene2194 7.956e-64 222.0 COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,2U956@28211|Alphaproteobacteria,3EZGG@335928|Xanthobacteraceae 28211|Alphaproteobacteria FG Scavenger mRNA decapping enzyme C-term binding MA20_36190 - - ko:K02503 - - - - ko00000,ko04147 - - - HIT CMS1_k127_4325627_7 1040989.AWZU01000011_gene4167 2.71e-20 91.0 COG3146@1|root,COG3146@2|Bacteria,1MU35@1224|Proteobacteria,2TS5I@28211|Alphaproteobacteria,3JRHQ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Peptidogalycan biosysnthesis/recognition MA20_36195 - - ko:K09919 - - - - ko00000 - - - FemAB_like CMS1_k127_438547_1 583355.Caka_0053 9.672e-11 70.0 2E6EA@1|root,3311R@2|Bacteria 2|Bacteria S Outer membrane protein beta-barrel domain - - - - - - - - - - - - OMP_b-brl CMS1_k127_438547_0 279714.FuraDRAFT_0533 1.254e-12 76.0 COG3637@1|root,COG3637@2|Bacteria,1N7U7@1224|Proteobacteria,2VRRF@28216|Betaproteobacteria,2KTSV@206351|Neisseriales 206351|Neisseriales M OmpA-like transmembrane domain - - - - - - - - - - - - OmpA_membrane CMS1_k127_438547_2 279714.FuraDRAFT_0533 0.0006343 43.0 COG3637@1|root,COG3637@2|Bacteria,1N7U7@1224|Proteobacteria,2VRRF@28216|Betaproteobacteria,2KTSV@206351|Neisseriales 206351|Neisseriales M OmpA-like transmembrane domain - - - - - - - - - - - - OmpA_membrane CMS1_k127_4401743_0 666684.AfiDRAFT_2974 1.518e-115 377.0 COG1192@1|root,COG1192@2|Bacteria,1N4FM@1224|Proteobacteria,2U05C@28211|Alphaproteobacteria,3JSM8@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria D Involved in chromosome partitioning MA20_42465 - - - - - - - - - - - - CMS1_k127_4401743_1 1429916.X566_03745 2.177e-31 128.0 COG0489@1|root,COG0489@2|Bacteria,1MWQ7@1224|Proteobacteria,2TWDW@28211|Alphaproteobacteria,3JR0J@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria D protein tyrosine kinase activity MA20_42470 - - - - - - - - - - - - CMS1_k127_4427539_0 1121924.ATWH01000004_gene2320 1.063e-206 657.0 COG1233@1|root,COG1233@2|Bacteria,2GJ80@201174|Actinobacteria 201174|Actinobacteria Q FAD dependent oxidoreductase - - - - - - - - - - - - Amino_oxidase,NAD_binding_8 CMS1_k127_4427539_2 1335760.ASTG01000016_gene181 2.034e-87 299.0 COG1028@1|root,COG1028@2|Bacteria,1N3A2@1224|Proteobacteria,2VF24@28211|Alphaproteobacteria,2K57Y@204457|Sphingomonadales 204457|Sphingomonadales IQ KR domain - - - - - - - - - - - - adh_short_C2 CMS1_k127_4427539_1 316055.RPE_1624 1.165e-157 504.0 COG3239@1|root,COG3239@2|Bacteria,1MY4I@1224|Proteobacteria,2TUF8@28211|Alphaproteobacteria,3JS8B@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I fatty acid desaturase des - 1.14.19.23,1.14.19.45 ko:K10255 ko02020,map02020 - - - ko00000,ko00001,ko01000,ko01004 - - - FA_desaturase CMS1_k127_4427539_3 1038860.AXAP01000010_gene7797 1.474e-79 276.0 COG2084@1|root,COG2084@2|Bacteria,1MV27@1224|Proteobacteria,2TTCZ@28211|Alphaproteobacteria,3JT36@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Domain of unknown function (DUF1932) - - - - - - - - - - - - DUF1932,NAD_binding_2 CMS1_k127_447052_4 748247.AZKH_0471 9.49e-30 122.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2VHEJ@28216|Betaproteobacteria,2KW0A@206389|Rhodocyclales 206389|Rhodocyclales E Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system - - 3.6.3.29,3.6.3.30 ko:K02010,ko:K02017,ko:K02052 ko02010,ko02024,map02010,map02024 M00189,M00190,M00193 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10,3.A.1.11,3.A.1.8 - - ABC_tran CMS1_k127_447052_2 1197906.CAJQ02000023_gene2520 3.204e-144 467.0 COG0329@1|root,COG0329@2|Bacteria,1MXI1@1224|Proteobacteria,2TTWT@28211|Alphaproteobacteria,3JT10@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria EM Belongs to the DapA family MA20_04665 - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS CMS1_k127_447052_1 709797.CSIRO_1524 1.822e-147 481.0 COG2244@1|root,COG2244@2|Bacteria,1MWKV@1224|Proteobacteria,2TTYS@28211|Alphaproteobacteria,3JSUH@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Polysaccharide biosynthesis protein MA20_18165 - - - - - - - - - - - Polysacc_synt,Polysacc_synt_C CMS1_k127_447052_0 1411123.JQNH01000001_gene3598 6.239e-244 763.0 COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2TRII@28211|Alphaproteobacteria 28211|Alphaproteobacteria I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases acsA2 - 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - AMP-binding,AMP-binding_C CMS1_k127_447052_3 114615.BRADO4112 2.491e-31 131.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria,3JRAF@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL,GGDEF,PAS_4,PAS_7,dCache_1 CMS1_k127_44830_1 1040989.AWZU01000014_gene4510 3.217e-171 547.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2TS6B@28211|Alphaproteobacteria,3JRU8@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Belongs to the peptidase S1C family htrA2 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030163,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051603,GO:0061077,GO:0070011,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 CMS1_k127_44830_2 883078.HMPREF9695_02320 1.707e-140 454.0 COG0604@1|root,COG0604@2|Bacteria,1MU4N@1224|Proteobacteria,2TRDI@28211|Alphaproteobacteria,3JUIN@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily MA20_35420 - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N_2 CMS1_k127_44830_3 172088.AUGA01000011_gene2632 3.659e-130 421.0 COG2010@1|root,COG2010@2|Bacteria,1MV6D@1224|Proteobacteria,2TT9U@28211|Alphaproteobacteria,3JVU8@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Cytochrome c - - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 CMS1_k127_44830_4 279714.FuraDRAFT_1484 5.082e-77 265.0 COG0625@1|root,COG0625@2|Bacteria,1RK1K@1224|Proteobacteria,2WEV9@28216|Betaproteobacteria 28216|Betaproteobacteria O Glutathione S-transferase, C-terminal domain - - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_N_3 CMS1_k127_44830_6 438753.AZC_0697 8.277e-66 239.0 COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,2TTP1@28211|Alphaproteobacteria,3EYAF@335928|Xanthobacteraceae 28211|Alphaproteobacteria K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate CMS1_k127_44830_9 867903.ThesuDRAFT_01256 3.201e-47 175.0 COG0400@1|root,COG0400@2|Bacteria,1VZ3H@1239|Firmicutes 1239|Firmicutes S carboxylic ester hydrolase activity - - - - - - - - - - - - - CMS1_k127_44830_7 1187851.A33M_2358 3.773e-64 222.0 COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,2U749@28211|Alphaproteobacteria,3FD6P@34008|Rhodovulum 28211|Alphaproteobacteria J Ribosomal protein L17 rplQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02879 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L17 CMS1_k127_44830_0 318996.AXAZ01000026_gene6973 9.231e-206 646.0 COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,2TSI0@28211|Alphaproteobacteria,3JS3G@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L CMS1_k127_44830_5 1038860.AXAP01000085_gene344 6.288e-68 233.0 COG0100@1|root,COG0100@2|Bacteria,1RD0A@1224|Proteobacteria,2U717@28211|Alphaproteobacteria,3JY0A@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome rpsK GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02948 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S11 CMS1_k127_44830_8 59538.XP_005965754.1 8.55e-63 218.0 COG0099@1|root,KOG3311@2759|Eukaryota 2759|Eukaryota J rRNA binding rps13 GO:0000313,GO:0000314,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005761,GO:0005763,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009507,GO:0009526,GO:0009532,GO:0009536,GO:0009570,GO:0009941,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0031967,GO:0031974,GO:0031975,GO:0032543,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044429,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0070013,GO:0071704,GO:0071840,GO:0098798,GO:0140053,GO:1901564,GO:1901566,GO:1901576,GO:1990904 2.7.7.6 ko:K02952,ko:K03040 ko00230,ko00240,ko01100,ko03010,ko03020,map00230,map00240,map01100,map03010,map03020 M00178,M00179,M00183 R00435,R00441,R00442,R00443 RC02795 br01610,br01611,ko00000,ko00001,ko00002,ko01000,ko03011,ko03021,ko03400 - - - Ribosomal_S13 CMS1_k127_4498167_0 443598.AUFA01000035_gene6194 0.0 1751.0 COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,2TSAE@28211|Alphaproteobacteria,3JTU5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Alpha-2-Macroglobulin MA20_30110 - - ko:K06894 - - - - ko00000 - - - A2M,A2M_N,A2M_N_2,MG1,PAN_1,Thiol-ester_cl CMS1_k127_4498167_24 652103.Rpdx1_2915 1.444e-30 121.0 COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,2TSAE@28211|Alphaproteobacteria,3JTU5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Alpha-2-Macroglobulin MA20_30110 - - ko:K06894 - - - - ko00000 - - - A2M,A2M_N,A2M_N_2,MG1,PAN_1,Thiol-ester_cl CMS1_k127_4498167_1 1230476.C207_00973 4.398e-273 860.0 COG4953@1|root,COG4953@2|Bacteria,1MUA9@1224|Proteobacteria,2TR2R@28211|Alphaproteobacteria,3JS2X@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Penicillin-Binding Protein C-terminus Family pbpC - 2.4.1.129 ko:K05367 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - BiPBP_C,Transgly,Transpeptidase CMS1_k127_4498167_2 1429916.X566_20340 1.292e-220 699.0 COG1807@1|root,COG1807@2|Bacteria,1NMIZ@1224|Proteobacteria,2TRS4@28211|Alphaproteobacteria,3JUHV@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M glycosyl transferase, family 39 MA20_30100 - - - - - - - - - - - PMT,PMT_2 CMS1_k127_4498167_20 1187851.A33M_0698 2.737e-53 199.0 COG0671@1|root,COG0671@2|Bacteria,1N7CW@1224|Proteobacteria,2TRDP@28211|Alphaproteobacteria 28211|Alphaproteobacteria I phosphoesterase, PA-phosphatase related lpxE - 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - PAP2 CMS1_k127_4498167_11 1304878.AUGD01000002_gene1624 1.283e-117 382.0 COG0463@1|root,COG0463@2|Bacteria,1MW2G@1224|Proteobacteria,2TTR9@28211|Alphaproteobacteria,3JRY7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Glycosyl transferase family 2 MA20_30090 - 2.4.1.83 ko:K00721 ko00510,ko01100,map00510,map01100 - R01009 RC00005 ko00000,ko00001,ko01000,ko01003 - GT2 - Glycos_transf_2 CMS1_k127_4498167_21 1187851.A33M_0700 2.697e-49 177.0 COG3952@1|root,COG3952@2|Bacteria,1MZ60@1224|Proteobacteria,2UCCY@28211|Alphaproteobacteria,3FDEP@34008|Rhodovulum 28211|Alphaproteobacteria S Lipid A Biosynthesis N-terminal domain - - - - - - - - - - - - LAB_N CMS1_k127_4498167_4 709797.CSIRO_3013 1.616e-178 566.0 COG0626@1|root,COG0626@2|Bacteria,1MU9E@1224|Proteobacteria,2TS8Z@28211|Alphaproteobacteria,3JT5G@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E cystathionine beta-lyase metC - 4.4.1.8 ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko00002,ko01000 - - - Cys_Met_Meta_PP CMS1_k127_4498167_5 936455.KI421499_gene2804 1.603e-166 528.0 COG0834@1|root,COG0834@2|Bacteria,1MV5D@1224|Proteobacteria,2TSRF@28211|Alphaproteobacteria,3JTG4@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria ET Belongs to the bacterial solute-binding protein 3 family MA20_30070 - - ko:K09969 ko02010,map02010 M00232 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.18,3.A.1.3.7,3.A.1.3.8 - - SBP_bac_3 CMS1_k127_4498167_6 1502851.FG93_03701 1.48e-161 517.0 COG4597@1|root,COG4597@2|Bacteria,1MV0S@1224|Proteobacteria,2TR7G@28211|Alphaproteobacteria,3JV9Y@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E amino acid ABC transporter - - - ko:K09970 ko02010,map02010 M00232 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.18,3.A.1.3.7,3.A.1.3.8 - - BPD_transp_1 CMS1_k127_4498167_7 1211115.ALIQ01000069_gene3472 1.363e-151 488.0 COG0765@1|root,COG0765@2|Bacteria,1MV3I@1224|Proteobacteria,2TR9C@28211|Alphaproteobacteria,3NA1H@45404|Beijerinckiaceae 28211|Alphaproteobacteria E Binding-protein-dependent transport system inner membrane component - - - ko:K09971 ko02010,map02010 M00232 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.18,3.A.1.3.7,3.A.1.3.8 - - BPD_transp_1 CMS1_k127_4498167_10 1532558.JL39_21095 1.018e-139 448.0 COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,2TQX2@28211|Alphaproteobacteria,4B8RS@82115|Rhizobiaceae 28211|Alphaproteobacteria E ABC-type polar amino acid transport system, ATPase component aapP - 3.6.3.21 ko:K02028,ko:K09972 ko02010,map02010 M00232,M00236 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3,3.A.1.3.17,3.A.1.3.18,3.A.1.3.7,3.A.1.3.8 - - ABC_tran CMS1_k127_4498167_12 1125973.JNLC01000016_gene2840 2.237e-103 347.0 COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,2TR9R@28211|Alphaproteobacteria,3JT1H@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P Rhodanese Homology Domain sseA GO:0003674,GO:0003824,GO:0004792,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009605,GO:0009987,GO:0009991,GO:0016740,GO:0016782,GO:0016783,GO:0016784,GO:0031668,GO:0033554,GO:0034641,GO:0042221,GO:0042262,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 - R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 - - - Rhodanese CMS1_k127_4498167_23 1197906.CAJQ02000047_gene4077 2.944e-33 145.0 COG2329@1|root,COG2329@2|Bacteria,1N2ZS@1224|Proteobacteria,2UEPY@28211|Alphaproteobacteria,3K08M@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Antibiotic biosynthesis monooxygenase - - - - - - - - - - - - - CMS1_k127_4498167_15 639283.Snov_1402 3.046e-95 319.0 COG2872@1|root,COG2872@2|Bacteria,1MY0P@1224|Proteobacteria,2TRRW@28211|Alphaproteobacteria,3F0WW@335928|Xanthobacteraceae 28211|Alphaproteobacteria S Threonyl and Alanyl tRNA synthetase second additional domain alaS2 GO:0000049,GO:0002161,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0097159,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K07050 - - - - ko00000,ko01000,ko03016 - - - tRNA-synt_2c,tRNA_SAD CMS1_k127_4498167_3 883078.HMPREF9695_01790 7.949e-181 573.0 COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,2TR4W@28211|Alphaproteobacteria,3JRM9@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Pyridoxal-phosphate dependent enzyme cysB GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 - - - PALP CMS1_k127_4498167_8 1187851.A33M_0714 2.807e-148 483.0 COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,2TRAF@28211|Alphaproteobacteria 28211|Alphaproteobacteria T GGDEF domain - - - - - - - - - - - - GGDEF CMS1_k127_4498167_14 1380394.JADL01000001_gene3041 5.386e-96 328.0 COG0683@1|root,COG0683@2|Bacteria,1MV3Y@1224|Proteobacteria,2TU2B@28211|Alphaproteobacteria,2JQHQ@204441|Rhodospirillales 204441|Rhodospirillales E Receptor family ligand binding region - - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 CMS1_k127_4498167_16 1380394.JADL01000001_gene3040 2.045e-90 306.0 COG0559@1|root,COG0559@2|Bacteria,1NQYP@1224|Proteobacteria,2TSH6@28211|Alphaproteobacteria,2JRU1@204441|Rhodospirillales 204441|Rhodospirillales E Branched-chain amino acid transport system / permease component - - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 CMS1_k127_4498167_13 1380394.JADL01000001_gene3039 5.415e-97 332.0 COG4177@1|root,COG4177@2|Bacteria,1MYF5@1224|Proteobacteria,2TUHM@28211|Alphaproteobacteria,2JS28@204441|Rhodospirillales 204441|Rhodospirillales E Branched-chain amino acid transport system / permease component - - - ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 CMS1_k127_4498167_18 1380394.JADL01000001_gene3038 5.3e-84 286.0 COG0411@1|root,COG0411@2|Bacteria,1MXHT@1224|Proteobacteria,2TSIU@28211|Alphaproteobacteria,2JRZV@204441|Rhodospirillales 204441|Rhodospirillales E Branched-chain amino acid ATP-binding cassette transporter - - - ko:K01995 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C CMS1_k127_4498167_19 1231391.AMZF01000020_gene1998 3.384e-81 278.0 COG0410@1|root,COG0410@2|Bacteria,1MUFR@1224|Proteobacteria,2VM45@28216|Betaproteobacteria 1224|Proteobacteria E abc transporter - - - ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran CMS1_k127_4498167_17 1120983.KB894573_gene97 2.797e-89 297.0 COG1917@1|root,COG1917@2|Bacteria,1QVVQ@1224|Proteobacteria,2TVET@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate nbaC GO:0000334,GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0044237,GO:0044248,GO:0051213,GO:0055114 1.13.11.6 ko:K00452 ko00380,ko01100,map00380,map01100 M00038 R02665 RC00387 ko00000,ko00001,ko00002,ko01000 - - - 3-HAO CMS1_k127_4498167_9 1123023.JIAI01000004_gene8204 4.695e-140 458.0 COG0620@1|root,COG0620@2|Bacteria,2H8H4@201174|Actinobacteria 201174|Actinobacteria E Methionine synthase - - - - - - - - - - - - Meth_synt_2 CMS1_k127_4498167_22 936455.KI421499_gene2722 3.544e-37 143.0 COG0006@1|root,COG0006@2|Bacteria,1MVJK@1224|Proteobacteria,2TVVP@28211|Alphaproteobacteria,3JSAA@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Creatinase/Prolidase N-terminal domain - - - - - - - - - - - - Creatinase_N,Peptidase_M24 CMS1_k127_4507441_3 420324.KI911948_gene9332 3.137e-76 257.0 COG0620@1|root,COG0620@2|Bacteria,1MV2Z@1224|Proteobacteria,2TSRH@28211|Alphaproteobacteria,1JYKD@119045|Methylobacteriaceae 28211|Alphaproteobacteria E Cobalamin-independent synthase, Catalytic domain MA20_07800 - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_2 CMS1_k127_4507441_1 1411123.JQNH01000001_gene2063 8.46e-141 458.0 COG0620@1|root,COG0620@2|Bacteria,1MV2Z@1224|Proteobacteria,2TSRH@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Methionine synthase MA20_07800 - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_2 CMS1_k127_4507441_4 335659.S23_47560 1.924e-40 162.0 COG0797@1|root,COG0797@2|Bacteria,1RDQ1@1224|Proteobacteria,2U7GC@28211|Alphaproteobacteria,3JYVJ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Lytic transglycolase - - - ko:K03642 - - - - ko00000 - - - DPBB_1 CMS1_k127_4507441_2 1123261.AXDW01000001_gene1166 6.816e-104 346.0 COG2030@1|root,COG2030@2|Bacteria,1MUR2@1224|Proteobacteria,1S3WX@1236|Gammaproteobacteria,1X99R@135614|Xanthomonadales 135614|Xanthomonadales I N-terminal half of MaoC dehydratase - - - - - - - - - - - - MaoC_dehydrat_N,MaoC_dehydratas CMS1_k127_4507441_0 438753.AZC_2509 1.822e-201 632.0 COG1960@1|root,COG1960@2|Bacteria,1MVAH@1224|Proteobacteria,2TR02@28211|Alphaproteobacteria,3F10R@335928|Xanthobacteraceae 28211|Alphaproteobacteria C Acyl-CoA dehydrogenase, middle domain MA20_04510 - 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N CMS1_k127_4510619_4 395964.KE386496_gene2881 3.867e-95 319.0 COG1011@1|root,COG1011@2|Bacteria,1MU1H@1224|Proteobacteria,2TQVC@28211|Alphaproteobacteria,3NB7M@45404|Beijerinckiaceae 28211|Alphaproteobacteria S HAD-hyrolase-like - - 3.8.1.2 ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05287 RC00697 ko00000,ko00001,ko01000 - - - HAD_2,Hydrolase CMS1_k127_4510619_1 639283.Snov_0517 1.503e-132 428.0 COG2267@1|root,COG2267@2|Bacteria,1MV7P@1224|Proteobacteria,2TSQ8@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Alpha beta hydrolase - - - - - - - - - - - - Hydrolase_4 CMS1_k127_4510619_0 631454.N177_3090 9.179e-194 616.0 COG3333@1|root,COG3333@2|Bacteria 2|Bacteria S Tripartite tricarboxylate transporter TctA family - - - - - - - - - - - - TctA CMS1_k127_4510619_9 1168059.KB899087_gene740 2.203e-13 77.0 2A9Y7@1|root,30Z6D@2|Bacteria,1PM33@1224|Proteobacteria,2UZQM@28211|Alphaproteobacteria,3F1ED@335928|Xanthobacteraceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_4510619_3 631454.N177_3817 1.627e-101 344.0 COG3181@1|root,COG3181@2|Bacteria,1NYMI@1224|Proteobacteria,2UTM7@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC CMS1_k127_4510619_8 1220582.RRU01S_15_00550 1.409e-57 202.0 COG0838@1|root,COG0838@2|Bacteria,1RGUT@1224|Proteobacteria,2U72Q@28211|Alphaproteobacteria,4BEKE@82115|Rhizobiaceae 28211|Alphaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 ko:K00330 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q4 CMS1_k127_4510619_2 690585.JNNU01000005_gene3040 7.148e-111 360.0 COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,2TQK3@28211|Alphaproteobacteria,4B8RC@82115|Rhizobiaceae 28211|Alphaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoB GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 ko:K00331 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q6 CMS1_k127_4510619_6 1187851.A33M_4049 5.685e-89 303.0 COG0852@1|root,COG0852@2|Bacteria,1MX4B@1224|Proteobacteria,2TSMT@28211|Alphaproteobacteria,3FCZ4@34008|Rhodovulum 28211|Alphaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoC GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 ko:K00332 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_30kDa CMS1_k127_4510619_7 1187851.A33M_4050 1.748e-60 211.0 COG5496@1|root,COG5496@2|Bacteria,1RKFT@1224|Proteobacteria,2U5DE@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Thioesterase - - 3.1.2.29 ko:K18700 - - - - ko00000,ko01000 - - - 4HBT CMS1_k127_4510619_5 670307.HYPDE_28853 1.166e-91 301.0 COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,2TQZ0@28211|Alphaproteobacteria,3N65X@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoD GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 ko:K00333 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_49kDa CMS1_k127_4511845_2 1122135.KB893134_gene3693 7.446e-78 265.0 COG5394@1|root,COG5394@2|Bacteria,1RHRC@1224|Proteobacteria,2TQWQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Polyhydroxyalkanoate synthesis repressor PhaR phaR - - - - - - - - - - - PHB_acc,PHB_acc_N CMS1_k127_4511845_0 1122135.KB893134_gene3692 3.516e-214 679.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2UP6H@28211|Alphaproteobacteria 28211|Alphaproteobacteria T GGDEF domain - - - - - - - - - - - - EAL,GGDEF,PAS_3 CMS1_k127_4511845_1 1304877.KI519399_gene2903 3.954e-159 514.0 COG0154@1|root,COG0154@2|Bacteria,1MWRI@1224|Proteobacteria,2TTJU@28211|Alphaproteobacteria,3JVBW@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Amidase - - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase CMS1_k127_4525738_6 1380394.JADL01000001_gene2255 5.057e-54 199.0 COG0500@1|root,COG2226@2|Bacteria,1R6ZI@1224|Proteobacteria,2TRC6@28211|Alphaproteobacteria,2JT16@204441|Rhodospirillales 204441|Rhodospirillales Q ubiE/COQ5 methyltransferase family - - - - - - - - - - - - Methyltransf_11 CMS1_k127_4525738_0 631454.N177_1019 3.782e-183 589.0 COG0189@1|root,COG0189@2|Bacteria,1MX5X@1224|Proteobacteria,2TT53@28211|Alphaproteobacteria,1JPSA@119043|Rhodobiaceae 28211|Alphaproteobacteria HJ RimK-like ATPgrasp N-terminal domain - - - - - - - - - - - - RLAN,RimK CMS1_k127_4525738_2 991905.SL003B_1644 4.781e-102 348.0 COG0454@1|root,COG0456@2|Bacteria,1MVZ2@1224|Proteobacteria,2TTA3@28211|Alphaproteobacteria,4BR43@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,DUF3335 CMS1_k127_4525738_7 1123368.AUIS01000029_gene1290 8.764e-50 182.0 COG1499@1|root,COG1499@2|Bacteria,1RD49@1224|Proteobacteria,1S4E9@1236|Gammaproteobacteria 1236|Gammaproteobacteria J ribosomal large subunit export from nucleus - - - - - - - - - - - - NMD3 CMS1_k127_4525738_8 402626.Rpic_4395 1.305e-35 142.0 COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,2VV0Q@28216|Betaproteobacteria,1KH82@119060|Burkholderiaceae 28216|Betaproteobacteria O Hsp20/alpha crystallin family - - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 CMS1_k127_4525738_5 1207063.P24_13693 6.854e-56 207.0 COG3618@1|root,COG3618@2|Bacteria,1N2QM@1224|Proteobacteria,2TTZK@28211|Alphaproteobacteria,2JS33@204441|Rhodospirillales 204441|Rhodospirillales S Amidohydrolase - - - - - - - - - - - - Amidohydro_2 CMS1_k127_4525738_3 1380394.JADL01000001_gene2219 7.894e-94 312.0 COG2514@1|root,COG2514@2|Bacteria,1PNKQ@1224|Proteobacteria,2VAA8@28211|Alphaproteobacteria,2JY35@204441|Rhodospirillales 204441|Rhodospirillales S Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase CMS1_k127_4525738_4 314262.MED193_14497 1.22e-83 291.0 COG0596@1|root,COG0596@2|Bacteria,1R4ZX@1224|Proteobacteria,2TU6R@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons dhaA - 3.8.1.5 ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05284,R05367,R05368,R05369,R05370,R07669,R07670 RC01317,RC01340,RC01341,RC02013 ko00000,ko00001,ko01000 - - - Abhydrolase_1,Abhydrolase_6 CMS1_k127_4525738_9 1095769.CAHF01000013_gene3178 3.386e-24 107.0 COG5470@1|root,COG5470@2|Bacteria,1N54U@1224|Proteobacteria 1224|Proteobacteria S Domain of unknown function (DUF1330) - - - - - - - - - - - - DUF1330 CMS1_k127_4525738_1 1380355.JNIJ01000026_gene1315 1.79e-104 357.0 COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,3JR8W@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Adenylate cyclase - - - - - - - - - - - - Guanylate_cyc,Trans_reg_C CMS1_k127_4533370_7 1187851.A33M_2799 9.088e-31 127.0 COG0697@1|root,COG0697@2|Bacteria,1MXVF@1224|Proteobacteria,2TU7N@28211|Alphaproteobacteria,3FDBI@34008|Rhodovulum 28211|Alphaproteobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA CMS1_k127_4533370_3 1120792.JAFV01000001_gene3429 5.417e-106 349.0 COG1028@1|root,COG1028@2|Bacteria,1MU2T@1224|Proteobacteria,2TSDG@28211|Alphaproteobacteria,370DR@31993|Methylocystaceae 28211|Alphaproteobacteria IQ Enoyl-(Acyl carrier protein) reductase MA20_27185 - 1.1.1.401 ko:K21883 ko00051,ko01120,map00051,map01120 - R11339 RC00089 ko00000,ko00001,ko01000 - - - adh_short,adh_short_C2 CMS1_k127_4533370_5 1116369.KB890024_gene3282 1.68e-73 258.0 COG0607@1|root,COG4275@1|root,COG0607@2|Bacteria,COG4275@2|Bacteria,1MYDE@1224|Proteobacteria,2TRC3@28211|Alphaproteobacteria,43IM5@69277|Phyllobacteriaceae 28211|Alphaproteobacteria P Chromate resistance exported protein - - - - - - - - - - - - Chrome_Resist,Rhodanese CMS1_k127_4533370_1 331869.BAL199_12031 4.57e-140 457.0 COG2059@1|root,COG2059@2|Bacteria,1MUBW@1224|Proteobacteria,2TRXF@28211|Alphaproteobacteria,4BQQ0@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria P Chromate transporter chrA - - ko:K07240 - - - - ko00000,ko02000 2.A.51.1 - - Chromate_transp CMS1_k127_4533370_2 1429916.X566_11400 9.226e-113 370.0 COG0600@1|root,COG0600@2|Bacteria,1MVAE@1224|Proteobacteria,2TSP5@28211|Alphaproteobacteria,3JS67@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P Binding-protein-dependent transport system inner membrane component MA20_40340 - - ko:K02050 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - BPD_transp_1 CMS1_k127_4533370_4 196490.AUEZ01000018_gene3364 5.769e-94 319.0 COG1116@1|root,COG1116@2|Bacteria,1MUIM@1224|Proteobacteria,2TRHM@28211|Alphaproteobacteria,3JQMP@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P ATPases associated with a variety of cellular activities - - - ko:K02049 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - ABC_tran CMS1_k127_4533370_0 1038860.AXAP01000010_gene7664 8.583e-164 522.0 COG0715@1|root,COG0715@2|Bacteria,1MXA3@1224|Proteobacteria,2TTW8@28211|Alphaproteobacteria,3JR3I@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P NMT1/THI5 like MA20_40330 - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 CMS1_k127_4533370_8 1336249.JADW01000001_gene2035 3.17e-05 56.0 2EB58@1|root,3355X@2|Bacteria,1RHC2@1224|Proteobacteria,2UBHI@28211|Alphaproteobacteria,4BF6C@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_4533370_6 1054213.HMPREF9946_00360 3.507e-65 225.0 COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,2TTWK@28211|Alphaproteobacteria,2JZPA@204441|Rhodospirillales 204441|Rhodospirillales E Cobalamin-independent synthase, Catalytic domain - - - - - - - - - - - - Meth_synt_2 CMS1_k127_4534741_4 1187851.A33M_0344 1.211e-66 239.0 COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,2TQU7@28211|Alphaproteobacteria,3FCMS@34008|Rhodovulum 28211|Alphaproteobacteria J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 mnmA - 2.8.1.13 ko:K00566 ko04122,map04122 - R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 - - - tRNA_Me_trans CMS1_k127_4534741_8 323097.Nham_0694 1.795e-34 149.0 COG3144@1|root,COG3144@2|Bacteria,1N7X4@1224|Proteobacteria,2UF9W@28211|Alphaproteobacteria,3JS1U@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria N Flagellar hook-length control protein FliK - - - ko:K10565 - - - - ko00000,ko02035 - - - Flg_hook CMS1_k127_4534741_3 1038860.AXAP01000028_gene561 3.659e-69 244.0 COG1843@1|root,COG1843@2|Bacteria,1MXCG@1224|Proteobacteria,2UCHH@28211|Alphaproteobacteria,3JRET@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria N Required for flagellar hook formation. May act as a scaffolding protein flgD - - ko:K02389 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FLgD_tudor,FlgD,FlgD_ig CMS1_k127_4534741_6 1297865.APJD01000018_gene5685 9.023e-51 181.0 2AMHV@1|root,31CDG@2|Bacteria,1RGVA@1224|Proteobacteria,2U98Q@28211|Alphaproteobacteria,3JZCI@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF1153) MA20_11245 - - - - - - - - - - - DUF1153 CMS1_k127_4534741_1 1187851.A33M_0340 4.982e-216 684.0 COG1766@1|root,COG1766@2|Bacteria,1MUQR@1224|Proteobacteria,2TR6J@28211|Alphaproteobacteria,3FD24@34008|Rhodovulum 28211|Alphaproteobacteria N The M ring may be actively involved in energy transduction fliF - - ko:K02409 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - YscJ_FliF,YscJ_FliF_C CMS1_k127_4534741_2 883078.HMPREF9695_00192 7.244e-179 565.0 COG1536@1|root,COG1536@2|Bacteria,1MV9X@1224|Proteobacteria,2TRIV@28211|Alphaproteobacteria,3JSDH@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria N FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation fliG - - ko:K02410 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02035 - - - FliG_C,FliG_M,FliG_N CMS1_k127_4534741_5 1187851.A33M_0338 3.246e-53 194.0 COG1317@1|root,COG1317@2|Bacteria,1NSNC@1224|Proteobacteria,2TUID@28211|Alphaproteobacteria 28211|Alphaproteobacteria N Flagellar biosynthesis type III secretory pathway protein fliH - - ko:K02411 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - FliH CMS1_k127_4534741_7 316057.RPD_3843 5.605e-41 154.0 COG1886@1|root,COG1886@2|Bacteria,1RGWT@1224|Proteobacteria,2UC6U@28211|Alphaproteobacteria,3JYS1@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation fliN GO:0005575,GO:0005623,GO:0005886,GO:0009288,GO:0009425,GO:0016020,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0071944 - ko:K02417 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - FliMN_C CMS1_k127_4534741_0 316056.RPC_0945 2.142e-228 714.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria,3JTQK@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Sigma-54 interaction domain flbD - - ko:K10943 ko02020,ko05111,map02020,map05111 M00515 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat CMS1_k127_4534741_9 1429916.X566_06055 3.476e-06 48.0 COG3502@1|root,COG3502@2|Bacteria,1MZEQ@1224|Proteobacteria,2UBR3@28211|Alphaproteobacteria,3JZ4V@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF952) MA20_22095 - - - - - - - - - - - DUF952 CMS1_k127_4536435_6 1187851.A33M_0466 1.445e-06 51.0 COG0842@1|root,COG0842@2|Bacteria,1MUF4@1224|Proteobacteria,2TRTS@28211|Alphaproteobacteria 28211|Alphaproteobacteria V Transport permease protein MA20_23385 - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane CMS1_k127_4536435_2 1187851.A33M_0467 5.346e-116 381.0 COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,2TR2P@28211|Alphaproteobacteria,3FEMK@34008|Rhodovulum 28211|Alphaproteobacteria V ATPases associated with a variety of cellular activities - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran CMS1_k127_4536435_0 1040989.AWZU01000017_gene3185 8.065e-172 550.0 COG0642@1|root,COG0642@2|Bacteria,1QU3Y@1224|Proteobacteria,2TVYH@28211|Alphaproteobacteria,3K6M5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T His Kinase A (phosphoacceptor) domain regB - 2.7.13.3 ko:K15011 ko02020,map02020 M00523 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA CMS1_k127_4536435_3 1187851.A33M_0472 1.182e-86 291.0 COG4567@1|root,COG4567@2|Bacteria,1RD7J@1224|Proteobacteria,2TSK7@28211|Alphaproteobacteria,3FD1K@34008|Rhodovulum 28211|Alphaproteobacteria K Bacterial regulatory protein, Fis family actR - - ko:K15012 ko02020,map02020 M00523 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg CMS1_k127_4536435_4 172088.AUGA01000006_gene8078 3.918e-62 222.0 COG5321@1|root,COG5321@2|Bacteria,1RDXW@1224|Proteobacteria,2U73Y@28211|Alphaproteobacteria,3JQPD@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S DNA repair protein MmcB-like MA20_23405 - - - - - - - - - - - MmcB-like CMS1_k127_4536435_1 1187851.A33M_1372 9.988e-170 548.0 COG0182@1|root,COG0182@2|Bacteria,1MUPM@1224|Proteobacteria,2TSPP@28211|Alphaproteobacteria,3FDW3@34008|Rhodovulum 28211|Alphaproteobacteria J Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) mtnA - 5.3.1.23 ko:K08963 ko00270,ko01100,map00270,map01100 M00034 R04420 RC01151 ko00000,ko00001,ko00002,ko01000 - - - IF-2B CMS1_k127_4536435_5 1502851.FG93_05608 7.579e-34 148.0 COG0657@1|root,COG0657@2|Bacteria,1MV3J@1224|Proteobacteria,2TUQ3@28211|Alphaproteobacteria,3JW6A@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I alpha/beta hydrolase fold - - 3.5.1.9 ko:K01432 ko00380,ko00630,ko01100,map00380,map00630,map01100 M00038 R00988,R01959,R04911 RC00263,RC00323 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_3 CMS1_k127_4540555_1 1211115.ALIQ01000199_gene517 3.933e-270 841.0 COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,2TQTG@28211|Alphaproteobacteria,3NAD0@45404|Beijerinckiaceae 28211|Alphaproteobacteria E B12 binding domain metH GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 M00017 R00946,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans CMS1_k127_4540555_12 316055.RPE_2090 3.933e-97 335.0 COG3921@1|root,COG3921@2|Bacteria,1N3WR@1224|Proteobacteria,2U1ZC@28211|Alphaproteobacteria,3JQY3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Extensin-like protein C-terminus - - - - - - - - - - - - Extensin-like_C CMS1_k127_4540555_8 1429916.X566_13280 1.966e-125 414.0 COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,2TT3I@28211|Alphaproteobacteria,3JSFB@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate ubiA - 2.5.1.39 ko:K03179,ko:K06125 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117,M00128 R05000,R05615,R05616,R07273 RC00209,RC02895 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA CMS1_k127_4540555_30 709797.CSIRO_0446 7.53e-22 103.0 28WB1@1|root,2ZIBH@2|Bacteria,1MXYB@1224|Proteobacteria,2U1VT@28211|Alphaproteobacteria,3JSP3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_4540555_14 1230476.C207_03481 2.124e-89 302.0 COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,2TS0N@28211|Alphaproteobacteria,3JUEI@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit rsmE - 2.1.1.193 ko:K09761 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_RNA CMS1_k127_4540555_25 1429916.X566_12675 1.339e-48 178.0 2CSH4@1|root,32SR7@2|Bacteria,1N366@1224|Proteobacteria,2UE8T@28211|Alphaproteobacteria,3JX2G@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_4540555_18 113395.AXAI01000001_gene3262 1.478e-77 267.0 COG3719@1|root,COG3719@2|Bacteria,1PTUN@1224|Proteobacteria,2TQUU@28211|Alphaproteobacteria,3JSX9@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Belongs to the RNase T2 family rns - 3.1.27.1,3.1.27.6 ko:K01166,ko:K01169 - - - - ko00000,ko01000,ko03016 - - - Ribonuclease_T2 CMS1_k127_4540555_11 883078.HMPREF9695_03323 3.993e-100 334.0 COG2961@1|root,COG2961@2|Bacteria,1MWGA@1224|Proteobacteria,2TU5K@28211|Alphaproteobacteria,3JUDU@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Specifically methylates the adenine in position 2030 of 23S rRNA rlmJ GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008988,GO:0009451,GO:0009987,GO:0010467,GO:0015976,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036307,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.266 ko:K07115 - - - - ko00000,ko01000,ko03009 - - - RsmJ CMS1_k127_4540555_28 335659.S23_60990 5.79e-35 137.0 COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2UF6W@28211|Alphaproteobacteria,3K03T@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K 'Cold-shock' DNA-binding domain MA20_05565 - - ko:K03704 - - - - ko00000,ko03000 - - - CSD CMS1_k127_4540555_19 991905.SL003B_1220 1.153e-73 254.0 COG0625@1|root,COG0625@2|Bacteria,1RHSK@1224|Proteobacteria,2U5GF@28211|Alphaproteobacteria,4BQSF@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria O Glutathione S-transferase, N-terminal domain MA20_19220 - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C_2,GST_N_3 CMS1_k127_4540555_26 1038858.AXBA01000016_gene1923 3.199e-48 181.0 COG3637@1|root,COG3637@2|Bacteria,1RKNU@1224|Proteobacteria,2U7U5@28211|Alphaproteobacteria,3EZJK@335928|Xanthobacteraceae 28211|Alphaproteobacteria M PFAM porin - - - ko:K16079 - - - - ko00000,ko02000 1.B.4.2.1 - - OMP_b-brl CMS1_k127_4540555_20 1038867.AXAY01000028_gene4811 2.494e-72 250.0 COG3637@1|root,COG3637@2|Bacteria,1MXV4@1224|Proteobacteria,2U0JD@28211|Alphaproteobacteria,3JTF8@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Outer membrane protein beta-barrel domain hbp2 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - ko:K16079 - - - - ko00000,ko02000 1.B.4.2.1 - - OMP_b-brl CMS1_k127_4540555_17 1187851.A33M_4289 3.813e-82 280.0 COG1028@1|root,COG1028@2|Bacteria,1MUUV@1224|Proteobacteria,2TR0A@28211|Alphaproteobacteria,3FD1A@34008|Rhodovulum 28211|Alphaproteobacteria IQ KR domain ptr1 - - - - - - - - - - - adh_short,adh_short_C2 CMS1_k127_4540555_0 709797.CSIRO_0236 5.017e-302 941.0 COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,2TT32@28211|Alphaproteobacteria,3JS2S@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision uvrC GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009380,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N CMS1_k127_4540555_6 1123060.JONP01000010_gene2300 2.894e-129 418.0 COG3485@1|root,COG3485@2|Bacteria,1QBMH@1224|Proteobacteria,2TVTJ@28211|Alphaproteobacteria,2JYT4@204441|Rhodospirillales 28211|Alphaproteobacteria Q Catechol dioxygenase N terminus chqB GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006725,GO:0008150,GO:0008152,GO:0008199,GO:0009056,GO:0009712,GO:0009987,GO:0016491,GO:0016701,GO:0016702,GO:0018576,GO:0018958,GO:0019114,GO:0019336,GO:0019439,GO:0019614,GO:0019615,GO:0042952,GO:0043167,GO:0043169,GO:0044237,GO:0044248,GO:0046872,GO:0046914,GO:0051213,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901575,GO:1901615,GO:1901616 1.13.11.1 ko:K03381 ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220 M00568 R00817,R04258,R05299,R08114,R08115,R09134 RC00388,RC00535,RC01366 ko00000,ko00001,ko00002,ko01000 - - - Dioxygenase_C,Dioxygenase_N CMS1_k127_4540555_15 1297863.APJF01000005_gene1855 3.514e-87 292.0 COG0558@1|root,COG0558@2|Bacteria,1RCZ7@1224|Proteobacteria,2TUI7@28211|Alphaproteobacteria,3JRMH@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pgsA - 2.7.8.41,2.7.8.5 ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 - R01801,R02030 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf CMS1_k127_4540555_27 426355.Mrad2831_5403 1.767e-36 139.0 COG1977@1|root,COG1977@2|Bacteria,1N0IE@1224|Proteobacteria,2UF4F@28211|Alphaproteobacteria,1JVMU@119045|Methylobacteriaceae 28211|Alphaproteobacteria H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin moaD - - ko:K03636 ko04122,map04122 - - - ko00000,ko00001 - - - ThiS CMS1_k127_4540555_22 1038859.AXAU01000023_gene841 1.807e-65 227.0 COG0314@1|root,COG0314@2|Bacteria,1RGUX@1224|Proteobacteria,2U73K@28211|Alphaproteobacteria,3JYB8@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H MoaE protein moaE - 2.8.1.12 ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09395 RC02507 ko00000,ko00001,ko01000 - - - MoaE CMS1_k127_4540555_5 450851.PHZ_c1121 9.485e-130 422.0 COG4257@1|root,COG4257@2|Bacteria,1QR8W@1224|Proteobacteria,2TRQ1@28211|Alphaproteobacteria 28211|Alphaproteobacteria V Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid - - - ko:K18235 - - - - ko00000,ko01000,ko01504 - - - - CMS1_k127_4540555_31 1232410.KI421428_gene1148 1.776e-17 92.0 COG0657@1|root,COG0657@2|Bacteria,1R74D@1224|Proteobacteria 1224|Proteobacteria I Protein of unknown function (DUF1460) - - - - - - - - - - - - DUF1460 CMS1_k127_4540555_4 1187851.A33M_2499 7.911e-164 519.0 COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,2TR1H@28211|Alphaproteobacteria,3FCQJ@34008|Rhodovulum 28211|Alphaproteobacteria E Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family ilvE - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_4 CMS1_k127_4540555_23 883080.HMPREF9697_01978 7.452e-65 227.0 COG1846@1|root,COG1846@2|Bacteria,1RIX7@1224|Proteobacteria,2U94M@28211|Alphaproteobacteria,3JVPT@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K helix_turn_helix multiple antibiotic resistance protein petP - - - - - - - - - - - MarR_2 CMS1_k127_4540555_9 1297863.APJF01000005_gene1865 2.022e-105 346.0 COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,2TSQF@28211|Alphaproteobacteria,3JSI0@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T transcriptional regulator, winged helix family petR - - ko:K07659 ko02020,ko02026,map02020,map02026 M00445,M00742,M00743 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C CMS1_k127_4540555_2 883078.HMPREF9695_03311 7.781e-233 731.0 COG0642@1|root,COG2205@2|Bacteria,1MUAK@1224|Proteobacteria,2TQRE@28211|Alphaproteobacteria,3JR9T@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain envZ - 2.7.13.3 ko:K07638 ko02020,ko02026,map02020,map02026 M00445,M00742,M00743 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA CMS1_k127_4540555_24 1038858.AXBA01000032_gene2585 1.918e-55 202.0 COG1309@1|root,COG1309@2|Bacteria,1QE3S@1224|Proteobacteria,2U3XG@28211|Alphaproteobacteria,3EZFS@335928|Xanthobacteraceae 28211|Alphaproteobacteria K transcriptional regulator - - - - - - - - - - - - TetR_N CMS1_k127_4540555_13 323097.Nham_3106 9.879e-94 321.0 COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,2TTY7@28211|Alphaproteobacteria,3JR3K@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline proC GO:0003674,GO:0003824,GO:0004735,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 - - - F420_oxidored,P5CR_dimer CMS1_k127_4540555_21 1187851.A33M_3037 2.965e-70 243.0 COG5465@1|root,COG5465@2|Bacteria,1REC1@1224|Proteobacteria,2U7UP@28211|Alphaproteobacteria,3FD8J@34008|Rhodovulum 28211|Alphaproteobacteria S Putative bacterial sensory transduction regulator MA20_05485 - - - - - - - - - - - YbjN CMS1_k127_4540555_3 1187851.A33M_3038 2.204e-167 530.0 COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,2TR4Y@28211|Alphaproteobacteria,3FCW1@34008|Rhodovulum 28211|Alphaproteobacteria F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) prs - 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyl_synth,Pribosyltran,Pribosyltran_N CMS1_k127_4540555_29 443598.AUFA01000008_gene4100 1.074e-33 140.0 2E5ZA@1|root,330NT@2|Bacteria,1NDA4@1224|Proteobacteria,2TUTP@28211|Alphaproteobacteria,3JWAB@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - MA20_05405 - - - - - - - - - - - - CMS1_k127_4540555_10 1187851.A33M_3041 2.72e-101 336.0 COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,2TTXU@28211|Alphaproteobacteria,3FCZ8@34008|Rhodovulum 28211|Alphaproteobacteria S Multi-copper polyphenol oxidoreductase laccase yfiH - - ko:K05810 - - - - ko00000,ko01000 - - - Cu-oxidase_4 CMS1_k127_4540555_7 1038860.AXAP01000013_gene1146 1.946e-125 415.0 COG1565@1|root,COG1565@2|Bacteria,1N3CJ@1224|Proteobacteria,2TRHW@28211|Alphaproteobacteria,3JRRQ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Putative S-adenosyl-L-methionine-dependent methyltransferase MA20_05390 - 2.1.1.79 ko:K00574,ko:K18164 ko04714,map04714 - - - ko00000,ko00001,ko01000,ko03029 - - - Methyltransf_28 CMS1_k127_4540555_16 1429916.X566_12795 5.322e-85 284.0 COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,2TTNS@28211|Alphaproteobacteria,3JQZ7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins lgt - - ko:K13292 - - - - ko00000,ko01000 - - - LGT CMS1_k127_4544251_10 883078.HMPREF9695_03132 5.275e-63 220.0 COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TQMW@28211|Alphaproteobacteria,3JSZE@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - 1.2.5.3 ko:K03520 - - R11168 RC02800 ko00000,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 CMS1_k127_4544251_9 196490.AUEZ01000007_gene5120 6.206e-69 238.0 COG2080@1|root,COG2080@2|Bacteria,1RCC9@1224|Proteobacteria,2U3X8@28211|Alphaproteobacteria,3JR9Z@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C [2Fe-2S] binding domain - - 1.2.5.3 ko:K03518 - - R11168 RC02800 ko00000,ko01000 - - - Fer2,Fer2_2 CMS1_k127_4544251_7 426355.Mrad2831_5854 5.213e-82 281.0 COG1319@1|root,COG1319@2|Bacteria,1MUDB@1224|Proteobacteria,2TTJF@28211|Alphaproteobacteria,1JRRF@119045|Methylobacteriaceae 28211|Alphaproteobacteria C CO dehydrogenase flavoprotein domain protein - - 1.2.5.3 ko:K03519 - - R11168 RC02800 ko00000,ko01000 - - - CO_deh_flav_C,FAD_binding_5 CMS1_k127_4544251_8 488538.SAR116_0921 2.271e-70 248.0 COG1028@1|root,COG1028@2|Bacteria 488538.SAR116_0921|- IQ oxidoreductase activity, acting on CH-OH group of donors - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - - CMS1_k127_4544251_4 1187851.A33M_2615 3.386e-122 403.0 COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,2TYM9@28211|Alphaproteobacteria 28211|Alphaproteobacteria CH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C CMS1_k127_4544251_3 649638.Trad_1887 5.038e-144 464.0 COG0346@1|root,COG0346@2|Bacteria,1WJ1B@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus E PFAM Glyoxalase bleomycin resistance protein dioxygenase - - 1.13.11.2 ko:K00446 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 M00569 R00816,R04089,R05295,R05404,R05406,R07795 RC00387,RC00643,RC01075,RC01364,RC01914 br01602,ko00000,ko00001,ko00002,ko01000 - - - Glyoxalase CMS1_k127_4544251_12 1502851.FG93_00844 1.599e-21 100.0 COG3232@1|root,COG3232@2|Bacteria,1RB8A@1224|Proteobacteria,2U5N5@28211|Alphaproteobacteria,3JYAP@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E 5-carboxymethyl-2-hydroxymuconate isomerase hpcD - 5.3.3.10 ko:K01826 ko00350,ko01120,ko01220,map00350,map01120,map01220 M00533 R04379,R04482 RC01141,RC01162 ko00000,ko00001,ko00002,ko01000 - - - CHMI CMS1_k127_4544251_5 1187851.A33M_2616 4.247e-115 378.0 COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,2TQMB@28211|Alphaproteobacteria,3FE5M@34008|Rhodovulum 28211|Alphaproteobacteria Q Fumarylacetoacetate (FAA) hydrolase family - - - - - - - - - - - - FAA_hydrolase CMS1_k127_4544251_6 1187851.A33M_2617 1.225e-107 361.0 COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,2TS99@28211|Alphaproteobacteria,3FD0F@34008|Rhodovulum 28211|Alphaproteobacteria E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) aroE - 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 - - - Shikimate_DH,Shikimate_dh_N CMS1_k127_4544251_11 1205680.CAKO01000040_gene803 2.09e-50 186.0 2B41E@1|root,31WRS@2|Bacteria,1P8VA@1224|Proteobacteria,2TT81@28211|Alphaproteobacteria,2JX93@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - CMS1_k127_4544251_13 1380394.JADL01000002_gene1096 2.406e-14 76.0 2EIDG@1|root,33C4V@2|Bacteria,1N0P4@1224|Proteobacteria,2UC9K@28211|Alphaproteobacteria,2JY84@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - CMS1_k127_4544251_1 709797.CSIRO_1015 6.714e-174 554.0 COG1073@1|root,COG1765@1|root,COG1073@2|Bacteria,COG1765@2|Bacteria,1N2BT@1224|Proteobacteria,2TQN7@28211|Alphaproteobacteria,3JQSS@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O OsmC-like protein MA20_16590 - - ko:K06889,ko:K07397 - - - - ko00000 - - - Hydrolase_4,OsmC CMS1_k127_4544251_0 1230476.C207_02921 5.625e-175 561.0 COG4949@1|root,COG4949@2|Bacteria,1MVI2@1224|Proteobacteria,2TSQJ@28211|Alphaproteobacteria,3JQRM@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF3422) - - - - - - - - - - - - DUF3422 CMS1_k127_4544251_2 1380355.JNIJ01000015_gene5968 9.104e-169 540.0 COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,2TQNW@28211|Alphaproteobacteria,3JSM5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C FMN-dependent dehydrogenase lldD - 1.1.2.3 ko:K00101 ko00620,ko01100,map00620,map01100 - R00196 RC00044 ko00000,ko00001,ko01000 - - - FMN_dh CMS1_k127_4544251_14 693986.MOC_5001 2.092e-13 72.0 COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,2TQWH@28211|Alphaproteobacteria,1JR1K@119045|Methylobacteriaceae 28211|Alphaproteobacteria G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate glmM - 5.4.2.10 ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 - R02060 RC00408 ko00000,ko00001,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV CMS1_k127_4553183_15 1410620.SHLA_70c000050 4.19e-48 184.0 COG4177@1|root,COG4177@2|Bacteria,1NY9G@1224|Proteobacteria,2TTSN@28211|Alphaproteobacteria,4BC4I@82115|Rhizobiaceae 28211|Alphaproteobacteria E Belongs to the binding-protein-dependent transport system permease family - - - ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 CMS1_k127_4553183_5 1123060.JONP01000011_gene3074 8.828e-132 437.0 COG0559@1|root,COG0559@2|Bacteria,1QDNH@1224|Proteobacteria,2U1CJ@28211|Alphaproteobacteria,2JTED@204441|Rhodospirillales 204441|Rhodospirillales E Branched-chain amino acid transport system / permease component - - - - - - - - - - - - BPD_transp_2 CMS1_k127_4553183_12 1207075.PputUW4_02742 4.324e-88 297.0 COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria 1224|Proteobacteria E ABC transporter - - - ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran CMS1_k127_4553183_9 1123060.JONP01000011_gene3076 2.01e-107 354.0 COG0411@1|root,COG0411@2|Bacteria,1MUFT@1224|Proteobacteria,2U22X@28211|Alphaproteobacteria,2JS5W@204441|Rhodospirillales 204441|Rhodospirillales E Branched-chain amino acid ATP-binding cassette transporter - - - - - - - - - - - - ABC_tran,BCA_ABC_TP_C CMS1_k127_4553183_2 384765.SIAM614_29051 5.403e-185 587.0 COG0683@1|root,COG0683@2|Bacteria,1N0MT@1224|Proteobacteria,2TUMI@28211|Alphaproteobacteria 28211|Alphaproteobacteria E ABC transporter substrate-binding protein - - - - - - - - - - - - Peripla_BP_6 CMS1_k127_4553183_6 1123060.JONP01000011_gene3078 1.266e-129 421.0 COG1250@1|root,COG1250@2|Bacteria,1MV8M@1224|Proteobacteria,2TRAW@28211|Alphaproteobacteria,2JW8Q@204441|Rhodospirillales 204441|Rhodospirillales I 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain - - - - - - - - - - - - 3HCDH,3HCDH_N CMS1_k127_4553183_7 1123060.JONP01000011_gene3079 1.005e-120 392.0 COG1028@1|root,COG1028@2|Bacteria,1R6F7@1224|Proteobacteria,2UNSJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria IQ KR domain - - - - - - - - - - - - adh_short_C2 CMS1_k127_4553183_17 1410620.SHLA_70c000120 3.063e-34 135.0 COG1917@1|root,COG1917@2|Bacteria,1N26Z@1224|Proteobacteria,2UHTK@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Cupin domain - - - - - - - - - - - - Cupin_2 CMS1_k127_4553183_3 1131814.JAFO01000001_gene1204 1.727e-161 511.0 COG1878@1|root,COG1878@2|Bacteria,1Q49R@1224|Proteobacteria,2UI8Z@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Putative cyclase - - - - - - - - - - - - Cyclase CMS1_k127_4553183_11 1123060.JONP01000011_gene3082 1.207e-92 317.0 COG1414@1|root,COG1414@2|Bacteria,1R4S7@1224|Proteobacteria,2URNG@28211|Alphaproteobacteria 28211|Alphaproteobacteria K transcriptional regulator - - - - - - - - - - - - HTH_IclR,IclR CMS1_k127_4553183_8 1123060.JONP01000011_gene3069 5.162e-111 368.0 COG2159@1|root,COG2159@2|Bacteria,1MXI7@1224|Proteobacteria,2U15G@28211|Alphaproteobacteria 28211|Alphaproteobacteria S metal-dependent hydrolase of the TIM-barrel fold - - 4.1.1.46 ko:K07045,ko:K14333,ko:K15063 ko00362,ko00627,ko01120,map00362,map00627,map01120 - R00821,R09278 RC00390 ko00000,ko00001,ko01000 - - - Amidohydro_2 CMS1_k127_4553183_22 426117.M446_0622 1.549e-09 64.0 2A6WY@1|root,30VRU@2|Bacteria,1PPMH@1224|Proteobacteria,2V238@28211|Alphaproteobacteria,1JY0S@119045|Methylobacteriaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_4553183_4 1297863.APJF01000013_gene4014 2.726e-135 437.0 COG1052@1|root,COG1052@2|Bacteria,1QVZS@1224|Proteobacteria,2TUUQ@28211|Alphaproteobacteria,3JT4E@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria CH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain MA20_01330 - 1.1.1.29,1.1.1.399,1.1.1.95 ko:K00018,ko:K00058 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00020,M00346 R00717,R01388,R01513 RC00031,RC00042 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C CMS1_k127_4553183_24 323097.Nham_2912 1.951e-09 62.0 2B21Y@1|root,303Z9@2|Bacteria,1NMH4@1224|Proteobacteria,2UJI8@28211|Alphaproteobacteria,3K1WI@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_4553183_0 1040989.AWZU01000032_gene3400 2.812e-313 964.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2TS7G@28211|Alphaproteobacteria,3JSN6@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter chvD - - ko:K15738 - - - - ko00000,ko02000 3.A.1.120.6 - - ABC_tran,ABC_tran_Xtn CMS1_k127_4553183_10 316058.RPB_1922 2.78e-96 321.0 COG4106@1|root,COG4106@2|Bacteria,1Q2Y3@1224|Proteobacteria,2TU5T@28211|Alphaproteobacteria,3JXPE@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate tam - 2.1.1.144 ko:K00598 - - - - ko00000,ko01000 - - - Methyltransf_23,Methyltransf_25,Methyltransf_31 CMS1_k127_4553183_23 1449049.JONW01000005_gene1248 1.569e-09 66.0 COG5470@1|root,COG5470@2|Bacteria,1PJI6@1224|Proteobacteria,2VAQG@28211|Alphaproteobacteria,2KJIC@204458|Caulobacterales 204458|Caulobacterales S Domain of unknown function (DUF1330) - - - - - - - - - - - - DUF1330 CMS1_k127_4553183_1 258594.RPA3603 5.518e-201 643.0 COG2951@1|root,COG3409@1|root,COG2951@2|Bacteria,COG3409@2|Bacteria,1MUZ3@1224|Proteobacteria,2TRD2@28211|Alphaproteobacteria,3JSF9@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Transglycosylase SLT domain MA20_01345 - - - - - - - - - - - PG_binding_1,SLT_2 CMS1_k127_4553183_20 504832.OCAR_7043 1.624e-15 80.0 2EB58@1|root,3355X@2|Bacteria,1RGB3@1224|Proteobacteria,2U9WS@28211|Alphaproteobacteria,3JZPT@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_4553183_19 1429916.X566_15020 1.465e-23 104.0 2EB58@1|root,3355X@2|Bacteria,1RGB3@1224|Proteobacteria,2U9WS@28211|Alphaproteobacteria,3JZPT@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_4553183_16 443598.AUFA01000007_gene4560 2.173e-35 141.0 COG1051@1|root,COG1051@2|Bacteria,1R5RJ@1224|Proteobacteria,2U1BJ@28211|Alphaproteobacteria,3JV0X@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria F NUDIX domain - - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX CMS1_k127_4553183_13 1380355.JNIJ01000028_gene731 1.484e-51 185.0 COG0346@1|root,COG0346@2|Bacteria,1RB65@1224|Proteobacteria,2U7DP@28211|Alphaproteobacteria,3JYA1@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily MA20_35640 - - - - - - - - - - - Glyoxalase,Glyoxalase_4 CMS1_k127_4553183_18 504832.OCAR_4452 5.988e-30 125.0 2BZQA@1|root,32WE5@2|Bacteria,1N533@1224|Proteobacteria,2UD0J@28211|Alphaproteobacteria,3K0KR@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Domain of Unknown Function (DUF930) - - - - - - - - - - - - DUF930 CMS1_k127_4553183_21 1285583.CCASEI_11735 5.092e-13 75.0 COG0662@1|root,COG0662@2|Bacteria,2GSNK@201174|Actinobacteria 201174|Actinobacteria G Lipocalin-like domain - - - - - - - - - - - - Lipocalin_5 CMS1_k127_4553183_25 272568.GDI3510 4.424e-09 67.0 2E9G8@1|root,333PF@2|Bacteria,1NBXU@1224|Proteobacteria,2VFX2@28211|Alphaproteobacteria,2JXTH@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - CMS1_k127_4553183_14 102125.Xen7305DRAFT_00021890 1.057e-50 186.0 COG1309@1|root,COG1309@2|Bacteria,1G5HM@1117|Cyanobacteria,3VKUF@52604|Pleurocapsales 1117|Cyanobacteria K Bacterial regulatory proteins, tetR family - - - ko:K16137 - - - - ko00000,ko03000 - - - TetR_C_11,TetR_C_13,TetR_C_6,TetR_N CMS1_k127_4555660_4 1120792.JAFV01000001_gene1925 5.34e-39 148.0 COG3293@1|root,COG3293@2|Bacteria,1QXE6@1224|Proteobacteria,2TX8K@28211|Alphaproteobacteria,371IP@31993|Methylocystaceae 28211|Alphaproteobacteria L Transposase DDE domain - - - - - - - - - - - - DDE_Tnp_1,DDE_Tnp_1_2 CMS1_k127_4555660_5 395965.Msil_1527 2.567e-31 124.0 COG3293@1|root,COG3293@2|Bacteria,1P5HD@1224|Proteobacteria,2TUQI@28211|Alphaproteobacteria,3NCEM@45404|Beijerinckiaceae 28211|Alphaproteobacteria L Putative transposase of IS4/5 family (DUF4096) - - - - - - - - - - - - DDE_Tnp_1,DDE_Tnp_1_2,DUF4096 CMS1_k127_4555660_2 402881.Plav_2931 3.444e-79 267.0 COG3832@1|root,COG3832@2|Bacteria,1N3W1@1224|Proteobacteria,2TSB4@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Activator of Hsp90 ATPase MA20_35785 - - - - - - - - - - - AHSA1 CMS1_k127_4555660_3 402881.Plav_2932 3.261e-44 163.0 COG0640@1|root,COG0640@2|Bacteria,1RH5P@1224|Proteobacteria,2U960@28211|Alphaproteobacteria,1JQH9@119043|Rhodobiaceae 28211|Alphaproteobacteria K PFAM regulatory protein ArsR - - - - - - - - - - - - HTH_20 CMS1_k127_4555660_7 1121106.JQKB01000006_gene1264 8.195e-20 91.0 2EIDG@1|root,33C4V@2|Bacteria,1N0P4@1224|Proteobacteria,2UC9K@28211|Alphaproteobacteria,2JY4Y@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - CMS1_k127_4555660_1 1037409.BJ6T_24310 1.034e-94 313.0 COG1765@1|root,COG1765@2|Bacteria,1MWPR@1224|Proteobacteria,2U1VW@28211|Alphaproteobacteria,3K19I@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O OsmC-like protein - - - - - - - - - - - - OsmC CMS1_k127_4555660_0 1380394.JADL01000018_gene1922 8.778e-149 476.0 2CCCK@1|root,2Z7UH@2|Bacteria,1R3SV@1224|Proteobacteria,2UH90@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_4555660_6 118161.KB235922_gene5051 1.026e-26 118.0 COG1309@1|root,COG1309@2|Bacteria,1G58W@1117|Cyanobacteria,3VN4I@52604|Pleurocapsales 1117|Cyanobacteria K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_C_13,TetR_N CMS1_k127_4559008_11 398525.KB900701_gene6379 2.479e-36 139.0 COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TQMW@28211|Alphaproteobacteria,3JSZE@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - 1.2.5.3 ko:K03520 - - R11168 RC02800 ko00000,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 CMS1_k127_4559008_15 794846.AJQU01000006_gene910 2.448e-11 68.0 2CBAE@1|root,31814@2|Bacteria,1R3F3@1224|Proteobacteria,2UBEH@28211|Alphaproteobacteria,4BP4R@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_4559008_17 1238182.C882_0137 7.944e-10 60.0 2CBAE@1|root,32YK1@2|Bacteria,1N7NP@1224|Proteobacteria,2UH5V@28211|Alphaproteobacteria,2JU5C@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - CMS1_k127_4559008_18 172088.AUGA01000057_gene3455 7.739e-07 60.0 COG3293@1|root,COG3293@2|Bacteria,1P5HD@1224|Proteobacteria,2TUQI@28211|Alphaproteobacteria,3JZFP@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L Transposase DDE domain - - - - - - - - - - - - DDE_Tnp_1_2,DUF4096 CMS1_k127_4559008_8 189753.AXAS01000041_gene2534 9.019e-64 231.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind CMS1_k127_4559008_6 1126627.BAWE01000004_gene3922 2.223e-86 297.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JYHD@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind CMS1_k127_4559008_14 1380355.JNIJ01000004_gene2847 1.754e-21 98.0 2ERZB@1|root,33JIF@2|Bacteria,1N1EU@1224|Proteobacteria,2UD07@28211|Alphaproteobacteria,3K01K@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_4559008_10 864051.BurJ1DRAFT_1192 3.381e-39 150.0 2CK8Q@1|root,31PVK@2|Bacteria,1RIRH@1224|Proteobacteria,2VUMH@28216|Betaproteobacteria,1KNKT@119065|unclassified Burkholderiales 28216|Betaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_4559008_1 639283.Snov_0226 1.207e-193 606.0 COG1878@1|root,COG1878@2|Bacteria,1MVWU@1224|Proteobacteria,2TUQ1@28211|Alphaproteobacteria,3F03T@335928|Xanthobacteraceae 28211|Alphaproteobacteria S Putative cyclase - - - - - - - - - - - - Cyclase CMS1_k127_4559008_0 1297863.APJF01000013_gene4060 5.026e-223 698.0 COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,2TS04@28211|Alphaproteobacteria,3JVVK@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine hisD2 - 1.1.1.308 ko:K15509 - - - - ko00000,ko01000 - - - Histidinol_dh CMS1_k127_4559008_13 622637.KE124774_gene1397 1.429e-21 109.0 COG2863@1|root,COG2863@2|Bacteria,1PEBJ@1224|Proteobacteria,2V88U@28211|Alphaproteobacteria,36YZX@31993|Methylocystaceae 28211|Alphaproteobacteria C Cytochrome c - - - - - - - - - - - - Cytochrom_C CMS1_k127_4559008_4 1187851.A33M_2612 2.467e-109 359.0 COG1028@1|root,COG1028@2|Bacteria,1PHT2@1224|Proteobacteria,2U6AA@28211|Alphaproteobacteria,3FE95@34008|Rhodovulum 28211|Alphaproteobacteria IQ KR domain - - - - - - - - - - - - adh_short_C2 CMS1_k127_4559008_12 366394.Smed_3147 1.048e-34 152.0 COG0715@1|root,COG0715@2|Bacteria,1Q20D@1224|Proteobacteria,2VF5Z@28211|Alphaproteobacteria 28211|Alphaproteobacteria P NMT1-like family - - - ko:K02051,ko:K15553 ko00920,ko02010,map00920,map02010 M00188,M00436 - - ko00000,ko00001,ko00002,ko02000 3.A.1.16,3.A.1.17,3.A.1.17.2 - - NMT1,NMT1_2 CMS1_k127_4559008_3 1187851.A33M_2610 2.583e-112 375.0 COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,2TSM8@28211|Alphaproteobacteria 28211|Alphaproteobacteria CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family - - 1.1.1.26 ko:K00015 ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120 - R00717,R01388 RC00031,RC00042 ko00000,ko00001,ko01000 - - - 2-Hacid_dh,2-Hacid_dh_C CMS1_k127_4559008_9 997350.HMPREF9129_0024 8.451e-54 207.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,22GQ5@1570339|Peptoniphilaceae 186801|Clostridia G Belongs to the PEP-utilizing enzyme family ppsA - 2.7.9.1,2.7.9.2 ko:K01006,ko:K01007 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 M00169,M00171,M00172,M00173,M00374 R00199,R00206 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PEP-utilizers_C,PPDK_N CMS1_k127_4559008_7 1121877.JQKF01000006_gene952 2.194e-84 295.0 COG0006@1|root,COG0006@2|Bacteria,2H45Q@201174|Actinobacteria 201174|Actinobacteria E Metallopeptidase family M24 - - - - - - - - - - - - Creatinase_N,Peptidase_M24 CMS1_k127_4559008_5 290400.Jann_2940 1.516e-92 314.0 COG0583@1|root,COG0583@2|Bacteria,1R550@1224|Proteobacteria,2U4SA@28211|Alphaproteobacteria 28211|Alphaproteobacteria K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate CMS1_k127_4559008_2 1187851.A33M_1620 1.603e-117 383.0 COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,2U25R@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Rhodanese Homology Domain - - 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 - R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 - - - Rhodanese CMS1_k127_4559008_16 196367.JNFG01000061_gene471 5.635e-11 65.0 COG0824@1|root,COG0824@2|Bacteria,1MZPN@1224|Proteobacteria,2VTCV@28216|Betaproteobacteria,1K82U@119060|Burkholderiaceae 28216|Betaproteobacteria S thioesterase - - 3.1.2.23 ko:K01075 ko00130,ko00362,ko01100,ko01110,ko01120,map00130,map00362,map01100,map01110,map01120 - R01301 RC00004,RC00174 ko00000,ko00001,ko01000 - - - 4HBT,4HBT_2 CMS1_k127_4562595_0 1038858.AXBA01000022_gene3582 2.579e-286 888.0 COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,2USBB@28211|Alphaproteobacteria,3EZ61@335928|Xanthobacteraceae 28211|Alphaproteobacteria M Penicillin-binding protein OB-like domain mrcA - 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - PCB_OB,Transgly,Transpeptidase CMS1_k127_4562595_1 319003.Bra1253DRAFT_01003 2.225e-112 367.0 COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,2TR9V@28211|Alphaproteobacteria,3JUE0@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA prfB - - ko:K02836 - - - - ko00000,ko03012 - - - PCRF,RF-1 CMS1_k127_4563342_1 1123393.KB891317_gene2348 1.053e-202 632.0 COG0538@1|root,COG0538@2|Bacteria,1MW3J@1224|Proteobacteria,2VHVD@28216|Betaproteobacteria,1KS5I@119069|Hydrogenophilales 119069|Hydrogenophilales C Isocitrate/isopropylmalate dehydrogenase - - 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh CMS1_k127_4563342_2 1123392.AQWL01000009_gene1135 7.625e-36 139.0 COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2VVTG@28216|Betaproteobacteria,1KTEM@119069|Hydrogenophilales 119069|Hydrogenophilales K 'Cold-shock' DNA-binding domain - - - ko:K03704 - - - - ko00000,ko03000 - - - CSD CMS1_k127_4563342_0 1123393.KB891317_gene2351 2.013e-208 651.0 COG4394@1|root,COG4394@2|Bacteria,1MYVF@1224|Proteobacteria,2VHIB@28216|Betaproteobacteria,1KRKI@119069|Hydrogenophilales 119069|Hydrogenophilales S Uncharacterized protein conserved in bacteria (DUF2331) - - - - - - - - - - - - DUF2331 CMS1_k127_4563342_3 292415.Tbd_0857 2.01e-13 70.0 COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,2VH4A@28216|Betaproteobacteria,1KRCA@119069|Hydrogenophilales 119069|Hydrogenophilales J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase efp - - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C CMS1_k127_4573742_0 448385.sce6009 7.965e-122 403.0 COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,42QJP@68525|delta/epsilon subdivisions,2WMET@28221|Deltaproteobacteria,2YVF6@29|Myxococcales 28221|Deltaproteobacteria Q PFAM multicopper oxidase type 2 ompC - 1.16.3.3 ko:K22350 - - - - ko00000,ko01000 - - - Cu-oxidase_2 CMS1_k127_4576026_2 1429916.X566_05435 3.608e-29 121.0 COG3180@1|root,COG3180@2|Bacteria,1MUFS@1224|Proteobacteria,2TUUX@28211|Alphaproteobacteria,3JRDZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Transition state regulatory protein AbrB MA20_20750 - - ko:K07120 - - - - ko00000 - - - AbrB CMS1_k127_4576026_1 1038859.AXAU01000005_gene5111 3.008e-236 751.0 COG0847@1|root,COG2905@1|root,COG0847@2|Bacteria,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,2TRZC@28211|Alphaproteobacteria,3JTXA@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Putative nucleotidyltransferase substrate binding domain - - 2.7.7.7 ko:K02342,ko:K07182 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - CBS,DUF294,DUF294_C,RNase_T,cNMP_binding CMS1_k127_4576026_0 1125973.JNLC01000010_gene1682 0.0 1427.0 COG0591@1|root,COG0642@1|root,COG0784@1|root,COG0591@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,2TR1M@28211|Alphaproteobacteria,3JTFW@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Histidine kinase MA20_19630 - - - - - - - - - - - HATPase_c,HisKA,PAS_7,Response_reg CMS1_k127_4577431_0 1288494.EBAPG3_18720 1.523e-49 177.0 COG1981@1|root,COG1981@2|Bacteria,1RHGS@1224|Proteobacteria,2VR5Y@28216|Betaproteobacteria,3737C@32003|Nitrosomonadales 28216|Betaproteobacteria S Uncharacterised protein family (UPF0093) - - - ko:K08973 - - - - ko00000 - - - UPF0093 CMS1_k127_4577431_1 555778.Hneap_1162 3.984e-30 135.0 COG1538@1|root,COG1538@2|Bacteria,1MWX5@1224|Proteobacteria,1S4SH@1236|Gammaproteobacteria,1WZF6@135613|Chromatiales 135613|Chromatiales MU Outer membrane efflux protein - - - - - - - - - - - - OEP CMS1_k127_4577431_2 743299.Acife_2418 6.823e-12 71.0 COG0845@1|root,COG0845@2|Bacteria,1NQZ0@1224|Proteobacteria,1RR67@1236|Gammaproteobacteria,2NCFT@225057|Acidithiobacillales 225057|Acidithiobacillales M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - - - - - - - - - - Biotin_lipoyl_2,HlyD_3 CMS1_k127_45824_0 991905.SL003B_1643 1.627e-220 694.0 COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,2TT2P@28211|Alphaproteobacteria,4BRCE@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria C Elongator protein 3, MiaB family, Radical SAM - - - - - - - - - - - - Radical_SAM CMS1_k127_45824_1 1379698.RBG1_1C00001G1831 1.395e-15 86.0 COG2706@1|root,COG4733@1|root,COG2706@2|Bacteria,COG4733@2|Bacteria,2NR81@2323|unclassified Bacteria 2|Bacteria G Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - 3.2.1.31 ko:K01195 ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142 M00014,M00076,M00077,M00078,M00129 R01478,R04979,R07818,R08127,R08260,R10830 RC00055,RC00171,RC00529,RC00530,RC00714,RC01251 ko00000,ko00001,ko00002,ko01000 - - - PKD,VCBS CMS1_k127_4586285_1 883078.HMPREF9695_02047 2.703e-171 539.0 COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,2TQZ0@28211|Alphaproteobacteria,3JSWA@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoD GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 ko:K00333 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_49kDa CMS1_k127_4586285_2 1187851.A33M_4053 1.882e-91 311.0 COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,2TSEJ@28211|Alphaproteobacteria,3FCWF@34008|Rhodovulum 28211|Alphaproteobacteria C Thioredoxin-like [2Fe-2S] ferredoxin nuoE - 1.6.5.3,1.6.99.3 ko:K00334,ko:K03943 ko00190,ko01100,ko04714,ko04723,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04714,map04723,map04932,map05010,map05012,map05016 M00143,M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1,3.D.1.6 - - 2Fe-2S_thioredx CMS1_k127_4586285_0 1187851.A33M_4054 9.901e-244 756.0 COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,2TRAH@28211|Alphaproteobacteria,3FCVJ@34008|Rhodovulum 28211|Alphaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain nuoF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 ko:K00335 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_51K,NADH_4Fe-4S,SLBB CMS1_k127_4586285_3 398580.Dshi_1319 1.539e-50 184.0 COG2329@1|root,COG2329@2|Bacteria,1RAC6@1224|Proteobacteria,2U59M@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Domain of unknown function (DUF3291) - - - - - - - - - - - - DUF3291 CMS1_k127_4586678_1 317655.Sala_1871 3.711e-148 477.0 COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,2TRN4@28211|Alphaproteobacteria,2K1GI@204457|Sphingomonadales 204457|Sphingomonadales E Glycine cleavage system T protein gcvT - 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 - - - GCV_T,GCV_T_C CMS1_k127_4586678_3 291985.CCSI01000003_gene270 1.401e-54 193.0 COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,2U9BY@28211|Alphaproteobacteria,2K5E0@204457|Sphingomonadales 204457|Sphingomonadales E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein gcvH - - ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 - - - GCV_H CMS1_k127_4586678_0 1144307.PMI04_02943 4.737e-231 721.0 COG0403@1|root,COG0403@2|Bacteria,1MVC1@1224|Proteobacteria,2TR6C@28211|Alphaproteobacteria,2K0IW@204457|Sphingomonadales 204457|Sphingomonadales E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvPA - 1.4.4.2 ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 - R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko01000 - - - GDC-P CMS1_k127_4586678_2 1248760.ANFZ01000009_gene1065 4.979e-137 443.0 COG1003@1|root,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,2TSFF@28211|Alphaproteobacteria,2K1GP@204457|Sphingomonadales 204457|Sphingomonadales E Glycine dehydrogenase (aminomethyl-transferring) gcvPB - 1.4.4.2 ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 - R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko01000 - - - Aminotran_5 CMS1_k127_4588105_1 1038860.AXAP01000011_gene257 4.702e-308 961.0 COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TQMW@28211|Alphaproteobacteria,3JS8F@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain MA20_08005 - 1.2.5.3 ko:K03520 - - R11168 RC02800 ko00000,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 CMS1_k127_4588105_10 438753.AZC_1821 1.623e-26 117.0 COG3909@1|root,COG3909@2|Bacteria,1N6Z5@1224|Proteobacteria,2UCBU@28211|Alphaproteobacteria,3F03S@335928|Xanthobacteraceae 28211|Alphaproteobacteria C Cytochrome C' - - - - - - - - - - - - Cytochrom_C_2 CMS1_k127_4588105_3 652103.Rpdx1_4232 1.098e-137 443.0 COG2010@1|root,COG2010@2|Bacteria,1MV6D@1224|Proteobacteria,2TT9U@28211|Alphaproteobacteria,3JSQ0@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Cytochrome c, mono- and diheme variants cycG - - - - - - - - - - - Cytochrom_C CMS1_k127_4588105_5 1187851.A33M_0892 6.473e-100 334.0 COG0697@1|root,COG0697@2|Bacteria,1MZXM@1224|Proteobacteria,2TSZM@28211|Alphaproteobacteria,3FD2B@34008|Rhodovulum 28211|Alphaproteobacteria EG EamA-like transporter family - - - ko:K15270 - - - - ko00000,ko02000 2.A.7.3.7 - - EamA CMS1_k127_4588105_9 316057.RPD_1627 4.387e-38 145.0 COG1522@1|root,COG1522@2|Bacteria,1MZDV@1224|Proteobacteria,2UBTU@28211|Alphaproteobacteria,3K0HQ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K Lrp/AsnC ligand binding domain QU41_18010 - - - - - - - - - - - AsnC_trans_reg CMS1_k127_4588105_6 1211115.ALIQ01000043_gene2948 3.735e-76 263.0 COG2145@1|root,COG2145@2|Bacteria,1MVES@1224|Proteobacteria,2U13N@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) thiM - 2.7.1.50 ko:K00878 ko00730,ko01100,map00730,map01100 M00127 R04448 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HK CMS1_k127_4588105_7 1187851.A33M_0956 1.1e-68 243.0 COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,2U6B1@28211|Alphaproteobacteria,3FDI7@34008|Rhodovulum 28211|Alphaproteobacteria H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) thiE - 2.5.1.3 ko:K00788 ko00730,ko01100,map00730,map01100 M00127 R03223,R10712 RC00224,RC03255,RC03397 ko00000,ko00001,ko00002,ko01000 - - - TMP-TENI CMS1_k127_4588105_4 1125973.JNLC01000001_gene114 1.215e-109 362.0 COG0351@1|root,COG0351@2|Bacteria,1MU9J@1224|Proteobacteria,2TUKR@28211|Alphaproteobacteria,3JRSS@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H Phosphomethylpyrimidine kinase thiD - 2.7.1.49,2.7.4.7 ko:K00941 ko00730,ko01100,map00730,map01100 M00127 R03471,R04509 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Phos_pyr_kin CMS1_k127_4588105_2 1187851.A33M_0954 2.652e-167 536.0 COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,2TS4J@28211|Alphaproteobacteria,3FD2D@34008|Rhodovulum 28211|Alphaproteobacteria Q Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - - - - - - - - - - DctP CMS1_k127_4588105_0 1230476.C207_04006 0.0 1039.0 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,3JR0R@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Response regulator receiver - - - - - - - - - - - - HATPase_c,HisKA,MASE1,PAS,PAS_4,PAS_9,Response_reg CMS1_k127_4588105_8 1502851.FG93_01033 6.464e-45 173.0 COG3637@1|root,COG3637@2|Bacteria,1NJWW@1224|Proteobacteria,2UD8G@28211|Alphaproteobacteria,3K68N@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Porin subfamily - - - ko:K16079 - - - - ko00000,ko02000 1.B.4.2.1 - - OMP_b-brl CMS1_k127_4589141_10 1380355.JNIJ01000011_gene916 1.507e-120 392.0 COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,2TT62@28211|Alphaproteobacteria,3JSQG@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Fatty acid desaturase - - 1.14.19.1 ko:K00507 ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212 - R02222 RC00917 ko00000,ko00001,ko01000,ko01004 - - - FA_desaturase CMS1_k127_4589141_9 631454.N177_2223 1.113e-125 409.0 COG0491@1|root,COG0491@2|Bacteria,1MURA@1224|Proteobacteria,2TR1F@28211|Alphaproteobacteria,1JNGZ@119043|Rhodobiaceae 28211|Alphaproteobacteria S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B CMS1_k127_4589141_7 631454.N177_3020 8.526e-134 434.0 COG0604@1|root,COG0604@2|Bacteria,1MWRK@1224|Proteobacteria,2TQMF@28211|Alphaproteobacteria,1JNWZ@119043|Rhodobiaceae 28211|Alphaproteobacteria C PFAM Alcohol dehydrogenase zinc-binding domain protein - - - - - - - - - - - - ADH_N,ADH_zinc_N CMS1_k127_4589141_3 631454.N177_3021 7.674e-155 502.0 COG1804@1|root,COG1804@2|Bacteria,1MW1H@1224|Proteobacteria,2TR7D@28211|Alphaproteobacteria,1JN9E@119043|Rhodobiaceae 28211|Alphaproteobacteria C CoA-transferase family III - - 5.1.99.4 ko:K01796 ko00120,ko01100,ko04146,map00120,map01100,map04146 M00104 R08734,R08739 RC02345 ko00000,ko00001,ko00002,ko01000 - - - CoA_transf_3 CMS1_k127_4589141_14 631454.N177_3022 1.512e-77 267.0 COG1250@1|root,COG1250@2|Bacteria,1NRT0@1224|Proteobacteria,2UP0A@28211|Alphaproteobacteria 28211|Alphaproteobacteria I 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain - - - - - - - - - - - - 3HCDH CMS1_k127_4589141_6 1197906.CAJQ02000024_gene1319 2.637e-140 454.0 COG1250@1|root,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2TSQG@28211|Alphaproteobacteria,3K2AP@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain - - 1.1.1.157 ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 - R01976,R05576,R06941 RC00029,RC00117 ko00000,ko00001,ko01000 - - - 3HCDH,3HCDH_N CMS1_k127_4589141_1 1197906.CAJQ02000024_gene1320 9.672e-173 554.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TTIR@28211|Alphaproteobacteria,3K3C0@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Acyl-CoA dehydrogenase, C-terminal domain - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N CMS1_k127_4589141_12 1123261.AXDW01000023_gene3570 7.754e-105 349.0 COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,1S758@1236|Gammaproteobacteria,1XCHN@135614|Xanthomonadales 135614|Xanthomonadales I Belongs to the enoyl-CoA hydratase isomerase family crt - 4.2.1.17 ko:K01715 ko00650,ko01200,map00650,map01200 - R03026 RC00831 ko00000,ko00001,ko01000 - - - ECH_1 CMS1_k127_4589141_0 1197906.CAJQ02000024_gene1327 8.371e-256 798.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2U43D@28211|Alphaproteobacteria,3JYZU@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria IQ AMP-binding enzyme - - - - - - - - - - - - AMP-binding,AMP-binding_C CMS1_k127_4589141_5 631454.N177_3028 5.689e-141 454.0 COG0447@1|root,COG0447@2|Bacteria,1QTZ2@1224|Proteobacteria,2U0ZZ@28211|Alphaproteobacteria,1JNW4@119043|Rhodobiaceae 28211|Alphaproteobacteria H Enoyl-CoA hydratase/isomerase - - 4.1.3.36 ko:K01661,ko:K07536 ko00130,ko00362,ko01100,ko01110,ko01120,ko01220,map00130,map00362,map01100,map01110,map01120,map01220 M00116,M00540 R05592,R07263 RC01429,RC01923 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 CMS1_k127_4589141_2 631454.N177_3029 5.88e-167 534.0 COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2TR7Q@28211|Alphaproteobacteria,1JMZU@119043|Rhodobiaceae 28211|Alphaproteobacteria C CoA-transferase family III - - - - - - - - - - - - CoA_transf_3 CMS1_k127_4589141_8 316057.RPD_1391 1.26e-126 419.0 COG2244@1|root,COG2244@2|Bacteria,1MWKV@1224|Proteobacteria,2TTYS@28211|Alphaproteobacteria,3JSUH@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Polysaccharide biosynthesis protein MA20_18165 - - - - - - - - - - - Polysacc_synt,Polysacc_synt_C CMS1_k127_4589141_15 272630.MexAM1_META1p0537 2.391e-57 217.0 COG5653@1|root,COG5653@2|Bacteria,1R6MM@1224|Proteobacteria,2U3T9@28211|Alphaproteobacteria,1JQVD@119045|Methylobacteriaceae 28211|Alphaproteobacteria M Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_6 CMS1_k127_4589141_4 316055.RPE_3593 1.767e-153 494.0 COG0654@1|root,COG0654@2|Bacteria,1MUEW@1224|Proteobacteria,2TUIB@28211|Alphaproteobacteria,3JU6H@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria CH FAD binding domain - - - - - - - - - - - - FAD_binding_3 CMS1_k127_4589141_13 402881.Plav_2995 1.176e-96 332.0 COG5653@1|root,COG5653@2|Bacteria,1MVAR@1224|Proteobacteria,2TTKY@28211|Alphaproteobacteria,1JQ6T@119043|Rhodobiaceae 28211|Alphaproteobacteria M Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_6 CMS1_k127_4589141_11 1037409.BJ6T_47140 1.216e-106 361.0 COG0438@1|root,COG0438@2|Bacteria,1MVKK@1224|Proteobacteria,2TSHP@28211|Alphaproteobacteria,3JTSD@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M glycosyl transferase group 1 MA20_36900 - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 CMS1_k127_4589141_16 1380355.JNIJ01000004_gene2874 3.294e-08 55.0 2E560@1|root,32ZYT@2|Bacteria,1RAE3@1224|Proteobacteria,2U5G6@28211|Alphaproteobacteria,3JY3P@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - MA20_01460 - - - - - - - - - - - - CMS1_k127_4589871_0 1211115.ALIQ01000225_gene1771 3.983e-246 776.0 COG0471@1|root,COG0471@2|Bacteria,1MU0K@1224|Proteobacteria,2TSFS@28211|Alphaproteobacteria 28211|Alphaproteobacteria P COG0471 Di- and tricarboxylate transporters - - - - - - - - - - - - CitMHS,Na_sulph_symp,TrkA_C CMS1_k127_4589871_1 1206739.BAGJ01000039_gene4585 4.786e-75 268.0 28J6C@1|root,2Z923@2|Bacteria,2IC95@201174|Actinobacteria,4FZBF@85025|Nocardiaceae 201174|Actinobacteria - - - - - - - - - - - - - - - CMS1_k127_4589871_2 1157708.KB907456_gene2211 6.833e-58 207.0 COG0625@1|root,COG0625@2|Bacteria,1NF66@1224|Proteobacteria,2VH33@28216|Betaproteobacteria,4AAIZ@80864|Comamonadaceae 28216|Betaproteobacteria O Glutathione S-transferase, C-terminal domain - - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C_2,GST_N_2,GST_N_3 CMS1_k127_4589871_3 1122603.ATVI01000011_gene1969 1.394e-15 83.0 COG3619@1|root,COG3619@2|Bacteria,1R5V0@1224|Proteobacteria,1S7R1@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF1275) - - - - - - - - - - - - DUF1275 CMS1_k127_4592194_4 331869.BAL199_01069 1.385e-99 327.0 COG2936@1|root,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,2TU0R@28211|Alphaproteobacteria,4BRPC@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria S X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain - - - ko:K06978 - - - - ko00000 - - - PepX_C,Peptidase_S15 CMS1_k127_4592194_2 331869.BAL199_01064 3.423e-160 510.0 KOG2165@1|root,2Z911@2|Bacteria,1N8JM@1224|Proteobacteria,2UQZ0@28211|Alphaproteobacteria 28211|Alphaproteobacteria S ubiquitin protein ligase binding - - - - - - - - - - - - - CMS1_k127_4592194_1 189753.AXAS01000114_gene7956 2.151e-169 545.0 COG0247@1|root,COG0247@2|Bacteria,1R4HN@1224|Proteobacteria,2U3WW@28211|Alphaproteobacteria,3JXJX@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C lactate metabolic process - - - - - - - - - - - - CCG,Fer4 CMS1_k127_4592194_0 883080.HMPREF9697_00482 0.0 1129.0 COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,2TQRQ@28211|Alphaproteobacteria,3JWK5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parC - - ko:K02621 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseA_C,DNA_topoisoIV CMS1_k127_4592194_6 113395.AXAI01000004_gene4456 1.688e-96 322.0 COG1381@1|root,COG1381@2|Bacteria,1MVEJ@1224|Proteobacteria,2TTYW@28211|Alphaproteobacteria,3JVK5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L Involved in DNA repair and RecF pathway recombination recO - - ko:K03584 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecO_C,RecO_N CMS1_k127_4592194_3 1411123.JQNH01000001_gene1201 1.115e-132 433.0 COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,2TSHM@28211|Alphaproteobacteria 28211|Alphaproteobacteria J An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism era - - ko:K03595 - - - - ko00000,ko03009,ko03029 - - - KH_2,MMR_HSR1 CMS1_k127_4592194_5 1187851.A33M_3052 2.841e-98 328.0 COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,2TTIA@28211|Alphaproteobacteria,3FD4P@34008|Rhodovulum 28211|Alphaproteobacteria J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism rnc GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 - - - ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 - - - Ribonucleas_3_3,dsrm CMS1_k127_4592194_7 1282876.BAOK01000002_gene374 1.132e-08 58.0 COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,2TR9N@28211|Alphaproteobacteria,4BQ0P@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria U Belongs to the peptidase S26 family lepB - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24 CMS1_k127_4594927_1 1040989.AWZU01000029_gene4325 5.687e-199 623.0 COG0651@1|root,COG0651@2|Bacteria,1MVBA@1224|Proteobacteria,2TSRU@28211|Alphaproteobacteria,3JWX4@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria CP Proton-conducting membrane transporter hyfF - - ko:K12141 - - - - ko00000,ko01000 - - - Proton_antipo_M CMS1_k127_4594927_0 1040989.AWZU01000029_gene4324 2.152e-239 752.0 COG3261@1|root,COG3262@1|root,COG3261@2|Bacteria,COG3262@2|Bacteria,1QUBF@1224|Proteobacteria,2TRE0@28211|Alphaproteobacteria,3JV9R@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Respiratory-chain NADH dehydrogenase, 49 Kd subunit hycE - - - - - - - - - - - Complex1_30kDa,Complex1_49kDa,NiFeSe_Hases CMS1_k127_4594927_10 189753.AXAS01000003_gene4559 2.544e-88 294.0 COG3260@1|root,COG3260@2|Bacteria,1QUBE@1224|Proteobacteria,2U279@28211|Alphaproteobacteria,3JTGI@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C NADH ubiquinone oxidoreductase, 20 Kd subunit hycG - - - - - - - - - - - Oxidored_q6 CMS1_k127_4594927_8 266265.Bxe_B2813 7.274e-110 363.0 COG0329@1|root,COG0329@2|Bacteria,1NQJ0@1224|Proteobacteria 1224|Proteobacteria EM Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS CMS1_k127_4594927_2 1187851.A33M_3410 1.4e-175 559.0 COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria,2TQXE@28211|Alphaproteobacteria 28211|Alphaproteobacteria S DinB superfamily - - - - - - - - - - - - DinB_2,FGE-sulfatase,Methyltransf_33 CMS1_k127_4594927_6 1245469.S58_48250 1.225e-115 381.0 COG4301@1|root,COG4301@2|Bacteria,1MUCG@1224|Proteobacteria,2TRMH@28211|Alphaproteobacteria,3JRIF@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Histidine-specific methyltransferase, SAM-dependent MA20_09135 - - - - - - - - - - - Methyltransf_33 CMS1_k127_4594927_5 78245.Xaut_3965 2.053e-121 396.0 COG3639@1|root,COG3639@2|Bacteria,1MW4F@1224|Proteobacteria,2TTXJ@28211|Alphaproteobacteria,3EZRP@335928|Xanthobacteraceae 28211|Alphaproteobacteria P TIGRFAM phosphonate ABC transporter, inner membrane subunit phnE - - ko:K02042 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - BPD_transp_1 CMS1_k127_4594927_7 1207063.P24_14609 9.934e-114 372.0 COG3639@1|root,COG3639@2|Bacteria,1MW4F@1224|Proteobacteria,2U1BD@28211|Alphaproteobacteria,2JS09@204441|Rhodospirillales 204441|Rhodospirillales P COG3639 ABC-type phosphate phosphonate transport system, permease component - - - - - - - - - - - - BPD_transp_1 CMS1_k127_4594927_4 981384.AEYW01000004_gene1806 2.515e-128 415.0 COG3638@1|root,COG3638@2|Bacteria,1MVE9@1224|Proteobacteria,2TRR3@28211|Alphaproteobacteria,4NB95@97050|Ruegeria 28211|Alphaproteobacteria P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system phnC - 3.6.3.28 ko:K02041 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.9 - - ABC_tran CMS1_k127_4594927_3 653733.Selin_2168 6.174e-137 445.0 COG3221@1|root,COG3221@2|Bacteria 2|Bacteria P organic phosphonate transport phnD - - ko:K02044 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - Phosphonate-bd CMS1_k127_4594927_9 744979.R2A130_3653 4.758e-97 326.0 COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,2TQMB@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) - - - - - - - - - - - - DUF2437,FAA_hydrolase CMS1_k127_4600464_14 114615.BRADO2153 2.042e-32 128.0 COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,2TQY2@28211|Alphaproteobacteria,3JRF1@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system aroC GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 - - - Chorismate_synt CMS1_k127_4600464_10 1038862.KB893917_gene4272 1.417e-62 224.0 COG0406@1|root,COG0406@2|Bacteria,1NPC4@1224|Proteobacteria,2U9WD@28211|Alphaproteobacteria,3JRMW@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G Phosphoglycerate mutase family gpmB - 5.4.2.12 ko:K15634 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 - - - His_Phos_1 CMS1_k127_4600464_1 1187851.A33M_3644 8.807e-144 460.0 COG0623@1|root,COG0623@2|Bacteria,1MV05@1224|Proteobacteria,2TSU4@28211|Alphaproteobacteria,3FCKR@34008|Rhodovulum 28211|Alphaproteobacteria I Enoyl-(Acyl carrier protein) reductase fabI2 - 1.3.1.10,1.3.1.9 ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 M00083,M00572 R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671 RC00052,RC00076,RC00120 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 CMS1_k127_4600464_9 1429916.X566_17185 1.762e-70 241.0 COG1595@1|root,COG1595@2|Bacteria,1MZMC@1224|Proteobacteria,2TU76@28211|Alphaproteobacteria,3JTYJ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K Belongs to the sigma-70 factor family. ECF subfamily MA20_07455 - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 CMS1_k127_4600464_8 316057.RPD_1310 4.233e-84 290.0 COG5662@1|root,COG5662@2|Bacteria,1RK1X@1224|Proteobacteria,2U8SM@28211|Alphaproteobacteria,3JTT0@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K transmembrane transcriptional regulator (Anti-sigma factor) MA20_07450 - - - - - - - - - - - zf-HC2 CMS1_k127_4600464_4 1187851.A33M_2815 1.155e-126 413.0 COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,2TRZ1@28211|Alphaproteobacteria,3FCIT@34008|Rhodovulum 28211|Alphaproteobacteria O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins dnaJ GO:0006457,GO:0008150,GO:0009987 - ko:K03686 - - - - ko00000,ko03029,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG CMS1_k127_4600464_12 1230476.C207_02960 1.03e-43 166.0 COG4520@1|root,COG4520@2|Bacteria,1N1T9@1224|Proteobacteria,2UCN2@28211|Alphaproteobacteria,3JYD9@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M 17 kDa outer membrane surface antigen MA20_07440 - - - - - - - - - - - 17kDa_Anti_2 CMS1_k127_4600464_5 438753.AZC_1197 5.702e-99 327.0 COG0259@1|root,COG0259@2|Bacteria,1NZUU@1224|Proteobacteria,2TT1U@28211|Alphaproteobacteria,3EXXX@335928|Xanthobacteraceae 28211|Alphaproteobacteria H Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) pdxH GO:0003674,GO:0003824,GO:0004733,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.4.3.5 ko:K00275 ko00750,ko01100,ko01120,map00750,map01100,map01120 M00124 R00277,R00278,R01710,R01711 RC00048,RC00116 ko00000,ko00001,ko00002,ko01000 - - - PNP_phzG_C,Putative_PNPOx CMS1_k127_4600464_3 1187851.A33M_2818 5.816e-133 427.0 COG1028@1|root,COG1028@2|Bacteria,1MVT2@1224|Proteobacteria,2TQKU@28211|Alphaproteobacteria,3FDQV@34008|Rhodovulum 28211|Alphaproteobacteria IQ Enoyl-(Acyl carrier protein) reductase fixR - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 CMS1_k127_4600464_2 1038859.AXAU01000002_gene297 4.131e-141 454.0 COG0598@1|root,COG0598@2|Bacteria,1MWMP@1224|Proteobacteria,2TQQD@28211|Alphaproteobacteria,3JTS3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P CorA-like Mg2+ transporter protein corA - - ko:K03284 - - - - ko00000,ko02000 1.A.35.1,1.A.35.3 - - CorA CMS1_k127_4600464_7 1380355.JNIJ01000018_gene4430 1.883e-95 317.0 COG1376@1|root,COG1376@2|Bacteria,1N43Q@1224|Proteobacteria,2U0V6@28211|Alphaproteobacteria,3JS6V@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S L,D-transpeptidase catalytic domain MA20_28870 - - - - - - - - - - - YkuD CMS1_k127_4600464_6 1101190.ARWB01000001_gene320 9.04e-97 329.0 COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,2TVHN@28211|Alphaproteobacteria,36Y0T@31993|Methylocystaceae 28211|Alphaproteobacteria S Calcineurin-like phosphoesterase superfamily domain ykuE - - ko:K07098 - - - - ko00000 - - - Metallophos CMS1_k127_4600464_11 316058.RPB_1166 8.847e-61 229.0 COG3921@1|root,COG3921@2|Bacteria,1PZMM@1224|Proteobacteria,2TR6H@28211|Alphaproteobacteria,3JV1V@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Extensin-like protein C-terminus - - - - - - - - - - - - Extensin-like_C CMS1_k127_4600464_0 266835.14027021 3.427e-282 875.0 COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,2TR96@28211|Alphaproteobacteria,43IT5@69277|Phyllobacteriaceae 28211|Alphaproteobacteria IQ AMP-binding enzyme C-terminal domain alkK - 6.2.1.44,6.2.1.48 ko:K00666,ko:K02182,ko:K20034 ko00920,map00920 - R10820 RC00004,RC00014 ko00000,ko00001,ko01000,ko01004 - - - AMP-binding,AMP-binding_C CMS1_k127_4600464_13 335659.S23_12990 4.027e-34 133.0 COG0624@1|root,COG0624@2|Bacteria,1MUSU@1224|Proteobacteria,2TS6M@28211|Alphaproteobacteria,3JV9F@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Peptidase dimerisation domain MA20_11215 - 3.4.17.11 ko:K01295 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 CMS1_k127_4606688_0 709797.CSIRO_4079 3.233e-256 802.0 COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,2TSHQ@28211|Alphaproteobacteria,3JSUN@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Penicillin-binding Protein ftsI - 3.4.16.4 ko:K03587 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011,ko03036 - - - PBP_dimer,Transpeptidase CMS1_k127_4606688_2 323097.Nham_1272 1.792e-25 109.0 COG5462@1|root,COG5462@2|Bacteria,1RBGN@1224|Proteobacteria,2U75N@28211|Alphaproteobacteria,3JY94@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S secreted (periplasmic) protein MA20_01770 - - - - - - - - - - - - CMS1_k127_4606688_1 443598.AUFA01000007_gene4579 2.899e-60 212.0 COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,2TRQA@28211|Alphaproteobacteria,3JT8T@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 - - - - ko00000,ko01000,ko03009 - - - Methyltransf_5 CMS1_k127_4610639_2 1168059.KB899087_gene3443 4.858e-54 193.0 COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,2TQZP@28211|Alphaproteobacteria,3EYAX@335928|Xanthobacteraceae 28211|Alphaproteobacteria OU Serine dehydrogenase proteinase sohB - - ko:K04773,ko:K04774 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49 CMS1_k127_4610639_5 1429916.X566_02575 3.194e-07 55.0 2AEVZ@1|root,314TJ@2|Bacteria,1N6PC@1224|Proteobacteria,2UF9D@28211|Alphaproteobacteria,3K13D@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_4610639_0 1040989.AWZU01000009_gene1092 5.682e-178 561.0 COG0752@1|root,COG0752@2|Bacteria,1MVCJ@1224|Proteobacteria,2TS2N@28211|Alphaproteobacteria,3JQY2@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J glycyl-tRNA synthetase alpha subunit glyQ - 6.1.1.14 ko:K01878 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2e CMS1_k127_4610639_4 1280949.HAD_15272 1.804e-28 121.0 COG3369@1|root,COG3369@2|Bacteria,1N6QZ@1224|Proteobacteria,2UGR1@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Iron-binding zinc finger CDGSH type - - - - - - - - - - - - zf-CDGSH CMS1_k127_4610639_1 1132836.RCCGE510_20199 2.065e-67 234.0 COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,2U6EM@28211|Alphaproteobacteria,4B7ZG@82115|Rhizobiaceae 28211|Alphaproteobacteria S LemA family lemA - - ko:K03744 - - - - ko00000 - - - LemA CMS1_k127_4610639_3 1532558.JL39_28475 7.977e-41 161.0 COG4907@1|root,COG4907@2|Bacteria,1MXPY@1224|Proteobacteria,2TUBP@28211|Alphaproteobacteria,4B77J@82115|Rhizobiaceae 28211|Alphaproteobacteria S Predicted membrane protein (DUF2207) - - - - - - - - - - - - DUF2207 CMS1_k127_4622002_7 1411123.JQNH01000001_gene1988 7.799e-17 91.0 COG2607@1|root,COG2607@2|Bacteria,1MVMX@1224|Proteobacteria,2TTFE@28211|Alphaproteobacteria 28211|Alphaproteobacteria P ATPase (AAA) MA20_41470 - - ko:K06923 - - - - ko00000 - - - DUF815 CMS1_k127_4622002_4 709797.CSIRO_2846 5.133e-45 167.0 COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,2UBZ6@28211|Alphaproteobacteria,3JYU5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria U Preprotein translocase subunit yajC - - ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - YajC CMS1_k127_4622002_0 883078.HMPREF9695_01944 7.143e-253 789.0 COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,2TQYG@28211|Alphaproteobacteria,3JSE2@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secD - - ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD_SecF,Sec_GG CMS1_k127_4622002_2 316055.RPE_2906 2.848e-149 477.0 COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,2TSFW@28211|Alphaproteobacteria,3JUBX@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA secF - - ko:K03072,ko:K03074 ko03060,ko03070,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 2.A.6.4,3.A.5.2,3.A.5.7 - - SecD_SecF,Sec_GG CMS1_k127_4622002_5 883078.HMPREF9695_01942 1.117e-37 158.0 COG3737@1|root,COG3737@2|Bacteria,1N083@1224|Proteobacteria,2U95K@28211|Alphaproteobacteria,3JYVC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF498/DUF598) MA20_41450 - - - - - - - - - - - DUF498 CMS1_k127_4622002_3 1122929.KB908227_gene3175 5.666e-71 251.0 COG1562@1|root,COG1562@2|Bacteria,1MX4W@1224|Proteobacteria,2U08T@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Phytoene squalene synthetase crtB - 2.5.1.32,2.5.1.99 ko:K02291,ko:K18163 ko00906,ko01062,ko01100,ko01110,ko04714,map00906,map01062,map01100,map01110,map04714 M00097 R02065,R04218,R07270,R10177 RC00362,RC01101,RC02869 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 - - - SQS_PSY CMS1_k127_4622002_1 243277.VC_A0877 5.135e-150 484.0 COG3049@1|root,COG3049@2|Bacteria,1MWPQ@1224|Proteobacteria,1RN43@1236|Gammaproteobacteria,1Y2CP@135623|Vibrionales 135623|Vibrionales M Linear amide C-N hydrolases, choloylglycine hydrolase family - - 3.5.1.24 ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 - R02797,R03975,R03977,R04486,R04487,R05835 RC00090,RC00096 ko00000,ko00001,ko01000 - - - CBAH CMS1_k127_4622002_6 981384.AEYW01000004_gene1771 1.297e-17 84.0 COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,2TTYC@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q COG1228 Imidazolonepropionase and related amidohydrolases - - - - - - - - - - - - Amidohydro_1 CMS1_k127_4622522_0 1125863.JAFN01000001_gene1462 6.143e-283 885.0 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2WJ4J@28221|Deltaproteobacteria 28221|Deltaproteobacteria P ATPase, P-type (transporting), HAD superfamily, subfamily IC copF - 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,HMA,Hydrolase,YHS CMS1_k127_4641046_0 95619.PM1_0230015 0.0 1017.0 COG3387@1|root,COG3387@2|Bacteria,1MV08@1224|Proteobacteria,1RS4U@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Glucoamylase and related glycosyl hydrolases - - - - - - - - - - - - Glyco_hydro_15 CMS1_k127_4641046_1 95619.PM1_0230010 6.492e-89 304.0 COG1877@1|root,COG1877@2|Bacteria,1RGY2@1224|Proteobacteria,1RNIQ@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Removes the phosphate from trehalose 6-phosphate to produce free trehalose otsB GO:0000287,GO:0003674,GO:0003824,GO:0004805,GO:0005488,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0009058,GO:0009266,GO:0009311,GO:0009312,GO:0009409,GO:0009628,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0033554,GO:0034637,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0046351,GO:0046872,GO:0050896,GO:0051716,GO:0070413,GO:0070415,GO:0070417,GO:0071704,GO:1901576 3.1.3.12 ko:K01087 ko00500,ko01100,map00500,map01100 - R02778 RC00017 ko00000,ko00001,ko01000 - - iE2348C_1286.E2348C_2018,iECED1_1282.ECED1_2163,iECIAI39_1322.ECIAI39_1155,iECS88_1305.ECS88_1952,iLF82_1304.LF82_1582,iNRG857_1313.NRG857_09495 Trehalose_PPase CMS1_k127_4646629_4 883078.HMPREF9695_00128 5.288e-66 232.0 COG4093@1|root,COG4093@2|Bacteria,1MXJA@1224|Proteobacteria,2TRH7@28211|Alphaproteobacteria,3JTXX@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Uncharacterized protein conserved in bacteria (DUF2125) MA20_20440 - - - - - - - - - - - DUF2125 CMS1_k127_4646629_2 1297865.APJD01000004_gene5321 2.519e-151 488.0 COG0287@1|root,COG0287@2|Bacteria,1QTZA@1224|Proteobacteria,2TS12@28211|Alphaproteobacteria,3JS3K@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Prephenate dehydrogenase tyrC GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0047794,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12,1.3.1.43 ko:K00210,ko:K00220,ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00025,M00040 R00732,R01728 RC00125 ko00000,ko00001,ko00002,ko01000 - - - PDH CMS1_k127_4646629_1 1187851.A33M_4418 8.4e-166 528.0 COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,2TQPN@28211|Alphaproteobacteria,3FCK8@34008|Rhodovulum 28211|Alphaproteobacteria E Aminotransferase class I and II hisC - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 CMS1_k127_4646629_3 652103.Rpdx1_4656 1.714e-112 370.0 COG1605@1|root,COG1605@2|Bacteria,1MWTP@1224|Proteobacteria,2TV3Z@28211|Alphaproteobacteria,3JTJ3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Chorismate mutase type II MA20_20425 - - - - - - - - - - - CM_2 CMS1_k127_4646629_0 1187851.A33M_4420 2.443e-209 655.0 COG2021@1|root,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,2TQYA@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine metXA GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 ko:K00641 ko00270,ko01100,ko01130,map00270,map01100,map01130 - R01776 RC00004,RC00041 ko00000,ko00001,ko01000 - - - Abhydrolase_1 CMS1_k127_465464_7 1038866.KB902851_gene287 7.582e-67 230.0 COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,2TQNE@28211|Alphaproteobacteria,3JS1I@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H Belongs to the prokaryotic GSH synthase family gshB GO:0003674,GO:0003824,GO:0004363,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0019184,GO:0034641,GO:0042398,GO:0043043,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044424,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901564,GO:1901566,GO:1901576 6.3.2.3 ko:K01920 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00497,R10994 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - - GSH-S_ATP,GSH-S_N CMS1_k127_465464_6 1038860.AXAP01000057_gene3472 1.623e-95 334.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2TQR7@28211|Alphaproteobacteria,3JTBE@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). MA20_16110 - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - 4HB_MCP_1,HAMP,MCPsignal,sCache_2 CMS1_k127_465464_10 316057.RPD_0400 2.073e-40 153.0 COG0792@1|root,COG0792@2|Bacteria,1N6VN@1224|Proteobacteria,2UFTM@28211|Alphaproteobacteria,3JZ0S@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L Belongs to the UPF0102 family MA20_24645 - - ko:K07460 - - - - ko00000 - - - UPF0102 CMS1_k127_465464_4 1125973.JNLC01000011_gene396 9.153e-111 366.0 COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,2TR14@28211|Alphaproteobacteria,3JTNR@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA rsmI - 2.1.1.198 ko:K07056 - - - - ko00000,ko01000,ko03009 - - - TP_methylase CMS1_k127_465464_2 316058.RPB_0422 6.442e-135 452.0 COG0683@1|root,COG0683@2|Bacteria,1QURG@1224|Proteobacteria,2TS62@28211|Alphaproteobacteria,3JR0B@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E LppC putative lipoprotein MA20_24635 - - - - - - - - - - - Peripla_BP_6 CMS1_k127_465464_0 196490.AUEZ01000033_gene6641 1.097e-185 591.0 COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,2TT63@28211|Alphaproteobacteria,3JTNX@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H Involved in the biosynthesis of porphyrin-containing compound hemN - - - - - - - - - - - HemN_C,Radical_SAM CMS1_k127_465464_5 1040989.AWZU01000042_gene90 7.914e-101 333.0 COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,2TV4B@28211|Alphaproteobacteria,3JTQ6@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions rdgB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 ko:K02428 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 - - - Ham1p_like CMS1_k127_465464_3 196490.AUEZ01000033_gene6639 8.136e-129 417.0 COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,2TRMC@28211|Alphaproteobacteria,3JRP7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates rph GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 ko:K00989 - - - - ko00000,ko01000,ko03016 - - - RNase_PH,RNase_PH_C CMS1_k127_465464_1 1297865.APJD01000028_gene5163 7.219e-174 552.0 COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,2TRUF@28211|Alphaproteobacteria,3JS5A@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons hrcA - - ko:K03705 - - - - ko00000,ko03000 - - - HrcA,HrcA_DNA-bdg CMS1_k127_465464_8 1187851.A33M_1175 3.633e-59 212.0 COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,2U5V2@28211|Alphaproteobacteria,3FDAQ@34008|Rhodovulum 28211|Alphaproteobacteria J Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ grpE GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - ko:K03687 - - - - ko00000,ko03029,ko03110 - - - GrpE CMS1_k127_465464_9 1429916.X566_08800 6.227e-41 160.0 28JYF@1|root,2Z9NQ@2|Bacteria,1MXUQ@1224|Proteobacteria,2TS50@28211|Alphaproteobacteria,3JV8F@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - MA20_24600 - - - - - - - - - - - - CMS1_k127_4658081_1 1449351.RISW2_10800 2.972e-247 773.0 COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2TSB1@28211|Alphaproteobacteria,4KKKQ@93682|Roseivivax 28211|Alphaproteobacteria EH Belongs to the TPP enzyme family - - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N CMS1_k127_4658081_0 1380355.JNIJ01000024_gene2345 9.007e-279 868.0 COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,2TS3Y@28211|Alphaproteobacteria,3JUHD@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Arginyl-tRNA synthetase argS - 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d CMS1_k127_4658081_5 316055.RPE_2692 3.442e-60 225.0 COG3115@1|root,COG3115@2|Bacteria,1RE0F@1224|Proteobacteria,2TWI2@28211|Alphaproteobacteria,3JTB5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria D Sporulation related domain - - - - - - - - - - - - SPOR CMS1_k127_4658081_2 335659.S23_34110 7.19e-135 437.0 COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,2TRJK@28211|Alphaproteobacteria,3JRM6@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G Glycosyl hydrolase family 3 N terminal domain nagZ - 3.2.1.21,3.2.1.52 ko:K01207,ko:K05349 ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501 M00628 R00022,R00026,R02558,R02887,R02985,R03527,R04949,R04998,R05963,R07809,R07810,R10035,R10039,R10040,R10831 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko00002,ko01000 - GH3 - Glyco_hydro_3 CMS1_k127_4658081_3 504832.OCAR_6270 1.115e-108 360.0 COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,2TS1V@28211|Alphaproteobacteria,3JR69@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves scpA - - ko:K05896 - - - - ko00000,ko03036 - - - SMC_ScpA CMS1_k127_4658081_4 1040989.AWZU01000003_gene6856 1.341e-102 342.0 COG1386@1|root,COG1386@2|Bacteria,1PUA6@1224|Proteobacteria,2TU64@28211|Alphaproteobacteria,3JUGS@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves scpB - - ko:K06024 - - - - ko00000,ko03036 - - - SMC_ScpB CMS1_k127_4658081_7 652103.Rpdx1_2655 1.377e-26 111.0 COG1826@1|root,COG1826@2|Bacteria,1NGDP@1224|Proteobacteria,2UFBN@28211|Alphaproteobacteria,3K08F@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system tatA GO:0003674,GO:0005215 - ko:K03116 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 CMS1_k127_4658081_6 1038866.KB902777_gene2949 7.146e-30 123.0 COG1826@1|root,COG1826@2|Bacteria,1N73F@1224|Proteobacteria,2UF4Z@28211|Alphaproteobacteria,3JVG6@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation tatB GO:0003674,GO:0005215 - ko:K03117 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 CMS1_k127_4658081_8 1297863.APJF01000008_gene738 7.545e-09 59.0 COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,2TTIX@28211|Alphaproteobacteria,3JRJG@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides tatC - - ko:K03118 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - TatC CMS1_k127_4660505_2 85643.Tmz1t_1424 6.45e-65 224.0 COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,2VJKV@28216|Betaproteobacteria,2KV7M@206389|Rhodocyclales 206389|Rhodocyclales J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA prfA - - ko:K02835 - - - - ko00000,ko03012 - - - PCRF,RF-1 CMS1_k127_4660505_1 1163408.UU9_04599 1.437e-86 295.0 COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,1RNGK@1236|Gammaproteobacteria,1X4AP@135614|Xanthomonadales 135614|Xanthomonadales J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif prmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 ko:K02493 - - R10806 RC00003,RC03279 ko00000,ko01000,ko03012 - - - MTS,Methyltransf_31 CMS1_k127_4660505_0 1122194.AUHU01000013_gene671 4.712e-94 314.0 COG0476@1|root,COG0476@2|Bacteria,1MW7H@1224|Proteobacteria,1RPJ3@1236|Gammaproteobacteria,466BQ@72275|Alteromonadaceae 1236|Gammaproteobacteria H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 moeB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0061605,GO:0070566,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.73,2.7.7.80 ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07459 RC00043 ko00000,ko00001,ko01000 - - iECIAI1_1343.ECIAI1_0865,iECW_1372.ECW_m0884,iEKO11_1354.EKO11_3059,iETEC_1333.ETEC_0893,iEcE24377_1341.EcE24377A_0897,iEcSMS35_1347.EcSMS35_0851,iWFL_1372.ECW_m0884 ThiF CMS1_k127_4660505_3 105559.Nwat_2742 2.896e-40 156.0 COG1310@1|root,COG1310@2|Bacteria,1RJSM@1224|Proteobacteria,1S86M@1236|Gammaproteobacteria,1X21I@135613|Chromatiales 135613|Chromatiales S SMART Mov34 MPN PAD-1 family protein - - - - - - - - - - - - Prok-JAB CMS1_k127_4660505_4 1049564.TevJSym_ak00410 4.64e-35 137.0 COG1704@1|root,COG1704@2|Bacteria,1R9YG@1224|Proteobacteria,1T06D@1236|Gammaproteobacteria,1J62H@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria S LemA family lemA - - ko:K03744 - - - - ko00000 - - - LemA CMS1_k127_466754_13 391595.RLO149_c028090 1.879e-16 85.0 28I63@1|root,2Z897@2|Bacteria,1N3VY@1224|Proteobacteria,2TTW0@28211|Alphaproteobacteria,2P1K6@2433|Roseobacter 28211|Alphaproteobacteria S Amino acid synthesis - - - - - - - - - - - - AA_synth CMS1_k127_466754_8 331869.BAL199_24114 1.311e-66 237.0 COG1082@1|root,COG1082@2|Bacteria,1N0QZ@1224|Proteobacteria,2UDUZ@28211|Alphaproteobacteria,4BSD5@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria G Xylose isomerase-like TIM barrel - - 3.1.21.2 ko:K01151 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - AP_endonuc_2 CMS1_k127_466754_10 485915.Dret_0949 4.236e-45 172.0 2EGX7@1|root,33APC@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - CMS1_k127_466754_9 745014.OMB55_00020010 1.749e-45 171.0 2DQBG@1|root,335T7@2|Bacteria,1R35T@1224|Proteobacteria 1224|Proteobacteria S Selenoprotein B glycine betaine sarcosine D-proline reductase - - 1.21.4.1 ko:K10794 ko00330,map00330 - R02825 RC00790 ko00000,ko00001,ko01000 - - - GRDB CMS1_k127_466754_11 485915.Dret_0949 3.648e-44 169.0 2EGX7@1|root,33APC@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - CMS1_k127_466754_12 666684.AfiDRAFT_2785 1.952e-43 164.0 2DQBG@1|root,335T7@2|Bacteria,1R35T@1224|Proteobacteria 1224|Proteobacteria S Selenoprotein B glycine betaine sarcosine D-proline reductase - - 1.21.4.1 ko:K10794 ko00330,map00330 - R02825 RC00790 ko00000,ko00001,ko01000 - - - GRDB CMS1_k127_466754_5 1333998.M2A_0292 2.481e-148 485.0 COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,2TS44@28211|Alphaproteobacteria,4BPIC@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria S Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane murJ - - ko:K03980 - - - - ko00000,ko01011,ko02000 2.A.66.4 - - MVIN CMS1_k127_466754_1 1121033.AUCF01000003_gene3430 0.0 1117.0 COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,2TSV0@28211|Alphaproteobacteria,2JPGY@204441|Rhodospirillales 204441|Rhodospirillales O Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen glnD GO:0006355,GO:0006464,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008150,GO:0008152,GO:0009605,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0018175,GO:0018177,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:1901564,GO:1901698,GO:1901699,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 2.7.7.59 ko:K00990 ko02020,map02020 - - - ko00000,ko00001,ko01000 - - - ACT,GlnD_UR_UTase,HD,NTP_transf_2 CMS1_k127_466754_0 1380394.JADL01000020_gene1828 0.0 1144.0 COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,2TQRR@28211|Alphaproteobacteria,2JPD6@204441|Rhodospirillales 204441|Rhodospirillales L This protein is involved in the repair of mismatches in DNA mutS - - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V CMS1_k127_466754_2 1380394.JADL01000020_gene1823 0.0 1099.0 COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,2TQJT@28211|Alphaproteobacteria,2JQEQ@204441|Rhodospirillales 204441|Rhodospirillales C malic enzyme tme - 1.1.1.40 ko:K00029 ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200 M00169,M00172 R00216 RC00105 ko00000,ko00001,ko00002,ko01000 - - - Malic_M,PTA_PTB,malic CMS1_k127_466754_6 1207063.P24_02926 7.959e-107 364.0 COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,2TR46@28211|Alphaproteobacteria,2JQBI@204441|Rhodospirillales 204441|Rhodospirillales T signal transduction histidine kinase phoR - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS_4,PAS_8 CMS1_k127_466754_4 1469245.JFBG01000019_gene1149 9.421e-151 484.0 COG0226@1|root,COG0226@2|Bacteria,1MUH9@1224|Proteobacteria,1RN9U@1236|Gammaproteobacteria,1WW68@135613|Chromatiales 135613|Chromatiales P phosphate binding protein - - - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like_2 CMS1_k127_466754_3 269796.Rru_A0599 5.008e-176 563.0 COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,2TQU1@28211|Alphaproteobacteria,2JQK1@204441|Rhodospirillales 204441|Rhodospirillales P probably responsible for the translocation of the substrate across the membrane pstC - - ko:K02037 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1,DUF3708 CMS1_k127_466754_7 243233.MCA1073 2.049e-70 246.0 COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,1RPV9@1236|Gammaproteobacteria,1XDQG@135618|Methylococcales 135618|Methylococcales P Phosphate transport system permease protein - - - ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1,DUF3333 CMS1_k127_4674417_0 316055.RPE_2973 2.325e-92 322.0 COG3164@1|root,COG3164@2|Bacteria,1MVDY@1224|Proteobacteria,2TSGG@28211|Alphaproteobacteria,3JTCH@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function MA20_30770 - - - - - - - - - - - AsmA_2,DUF3971 CMS1_k127_4677026_0 1336243.JAEA01000009_gene126 2.089e-202 634.0 COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,2TQSI@28211|Alphaproteobacteria,1JRHE@119045|Methylobacteriaceae 28211|Alphaproteobacteria I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate ispG GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R08689,R10859 RC01486 ko00000,ko00001,ko00002,ko01000 - - - GcpE CMS1_k127_4677026_1 1245469.S58_70950 7.852e-94 317.0 COG0697@1|root,COG0697@2|Bacteria,1R6KH@1224|Proteobacteria,2TTBR@28211|Alphaproteobacteria,3JWIF@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria EG EamA-like transporter family MA20_23245 - - - - - - - - - - - EamA CMS1_k127_4677026_2 709797.CSIRO_2382 2.043e-65 228.0 2CK39@1|root,32SBG@2|Bacteria,1MZ6F@1224|Proteobacteria,2UBT5@28211|Alphaproteobacteria,3JYTE@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Phage gp6-like head-tail connector protein - - - - - - - - - - - - Phage_connect_1 CMS1_k127_4677026_4 1187851.A33M_0399 1.228e-21 102.0 COG5614@1|root,COG5614@2|Bacteria,1NFD0@1224|Proteobacteria 1224|Proteobacteria S Phage head-tail joining protein - - - - - - - - - - - - Phage_H_T_join CMS1_k127_4677026_3 652103.Rpdx1_3613 1.012e-33 137.0 2E3NG@1|root,32YKK@2|Bacteria,1NBBS@1224|Proteobacteria,2UGKW@28211|Alphaproteobacteria,3JZAK@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF3168) - - - - - - - - - - - - DUF3168 CMS1_k127_4696721_2 323097.Nham_2437 8.887e-80 268.0 COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,1MUFZ@1224|Proteobacteria,2TRGN@28211|Alphaproteobacteria,3JSU4@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom CMS1_k127_4696721_1 1336243.JAEA01000010_gene3425 2.426e-110 369.0 COG2951@1|root,COG3409@1|root,COG2951@2|Bacteria,COG3409@2|Bacteria,1MUZ3@1224|Proteobacteria,2TRP0@28211|Alphaproteobacteria,1JQR3@119045|Methylobacteriaceae 28211|Alphaproteobacteria M TIGRFAM lytic murein transglycosylase - - - ko:K00786,ko:K08305 - - - - ko00000,ko01000,ko01011 - GH103 - PG_binding_1,SLT_2 CMS1_k127_4696721_0 323097.Nham_2285 8.194e-141 456.0 COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,2TRQE@28211|Alphaproteobacteria,3JU47@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria LU DNA recombination-mediator protein A dprA - - ko:K04096 - - - - ko00000 - - - DNA_processg_A CMS1_k127_4696721_3 323097.Nham_2284 8.757e-24 102.0 COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,2U7BZ@28211|Alphaproteobacteria,3JRDJ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP plsY - 2.3.1.15 ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - G3P_acyltransf CMS1_k127_4698891_2 1163617.SCD_n00497 1.632e-07 53.0 COG2027@1|root,COG2027@2|Bacteria,1MW40@1224|Proteobacteria,2VH20@28216|Betaproteobacteria 28216|Betaproteobacteria M D-alanyl-D-alanine carboxypeptidase dacB - 3.4.16.4 ko:K07259 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - Peptidase_S13 CMS1_k127_4698891_0 441620.Mpop_5222 1.68e-174 557.0 COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,2TS63@28211|Alphaproteobacteria,1JRMQ@119045|Methylobacteriaceae 28211|Alphaproteobacteria C Belongs to the citrate synthase family gltA - 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt CMS1_k127_4698891_1 338963.Pcar_2627 1.895e-21 100.0 2EHUK@1|root,33BK8@2|Bacteria,1Q1PA@1224|Proteobacteria,437D9@68525|delta/epsilon subdivisions,2X2JB@28221|Deltaproteobacteria,43VPA@69541|Desulfuromonadales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_4714383_1 1126627.BAWE01000002_gene356 1.455e-225 704.0 COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,2TSE2@28211|Alphaproteobacteria,3JS73@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C NADH NADPH, small subunit gltD - 1.4.1.13,1.4.1.14 ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - Fer4_20,Pyr_redox_2 CMS1_k127_4714383_0 1187851.A33M_4165 0.0 2517.0 COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,2TRHQ@28211|Alphaproteobacteria,3FCN4@34008|Rhodovulum 28211|Alphaproteobacteria E Glutamate synthase central domain gltB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14 ko:K00265 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 - R00093,R00114,R00248 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase CMS1_k127_4714383_6 743836.AYNA01000141_gene257 3.863e-31 133.0 COG2259@1|root,COG2259@2|Bacteria,1N1VA@1224|Proteobacteria,2TVZ9@28211|Alphaproteobacteria,36YHY@31993|Methylocystaceae 28211|Alphaproteobacteria S DoxX - - - ko:K15977 - - - - ko00000 - - - DoxX CMS1_k127_4714383_9 1297863.APJF01000005_gene1821 5.602e-06 56.0 COG3147@1|root,COG3147@2|Bacteria,1MVVA@1224|Proteobacteria,2U3ZH@28211|Alphaproteobacteria,3JWHM@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Non-essential cell division protein that could be required for efficient cell constriction - - - - - - - - - - - - - CMS1_k127_4714383_5 316055.RPE_0685 7.675e-62 219.0 COG0071@1|root,COG0071@2|Bacteria,1RH2X@1224|Proteobacteria,2U96D@28211|Alphaproteobacteria,3JYEA@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O Belongs to the small heat shock protein (HSP20) family ibpA - - ko:K04080 - - - - ko00000,ko03110 - - - HSP20 CMS1_k127_4714383_3 1298867.AUES01000026_gene2993 1.103e-134 436.0 COG2267@1|root,COG2267@2|Bacteria,1MWDA@1224|Proteobacteria,2TSZ4@28211|Alphaproteobacteria,3JU64@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Serine aminopeptidase, S33 pldB - 3.1.1.5 ko:K01048 ko00564,map00564 - - - ko00000,ko00001,ko01000 - - - Hydrolase_4 CMS1_k127_4714383_8 1538295.JY96_05700 1.756e-10 69.0 29DIQ@1|root,300GG@2|Bacteria,1RJVY@1224|Proteobacteria,2VTHH@28216|Betaproteobacteria,1KMUD@119065|unclassified Burkholderiales 28216|Betaproteobacteria S Protein of unknown function (DUF3617) - - - - - - - - - - - - DUF3617 CMS1_k127_4714383_4 1187851.A33M_4169 3.675e-119 388.0 COG0483@1|root,COG0483@2|Bacteria,1PPJ0@1224|Proteobacteria,2TQTX@28211|Alphaproteobacteria,3FD04@34008|Rhodovulum 28211|Alphaproteobacteria G Inositol monophosphatase family hisN - 3.1.3.15,3.1.3.25,3.1.3.93 ko:K01092,ko:K18649 ko00053,ko00340,ko00521,ko00562,ko01100,ko01110,ko01230,ko04070,map00053,map00340,map00521,map00562,map01100,map01110,map01230,map04070 M00026,M00114,M00131 R01185,R01186,R01187,R03013,R07674 RC00017,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P CMS1_k127_4714383_2 1187851.A33M_4170 1.699e-147 473.0 COG3741@1|root,COG3741@2|Bacteria,1MY4D@1224|Proteobacteria,2TUPZ@28211|Alphaproteobacteria,3FD16@34008|Rhodovulum 28211|Alphaproteobacteria E N-formylglutamate amidohydrolase MA20_06380 - 3.5.1.68 ko:K01458 ko00340,ko00630,map00340,map00630 - R00525 RC00165,RC00323 ko00000,ko00001,ko01000 - - - FGase CMS1_k127_4714383_7 323098.Nwi_2946 3.804e-24 102.0 COG0745@1|root,COG0745@2|Bacteria,1QUSA@1224|Proteobacteria,2TW5G@28211|Alphaproteobacteria,3JYPM@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria KT Response regulator receiver QU41_05915 - - ko:K13589 ko02020,ko04112,map02020,map04112 M00512 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg CMS1_k127_4720160_0 883080.HMPREF9697_02680 2.003e-252 795.0 COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1MWKS@1224|Proteobacteria,2TQV8@28211|Alphaproteobacteria,3JUGP@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily pheT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - B3_4,B5,FDX-ACB,tRNA_bind CMS1_k127_4720160_1 652103.Rpdx1_0038 3.158e-161 508.0 COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,2TS2T@28211|Alphaproteobacteria,3JTB6@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily pheS GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Phe_tRNA-synt_N,tRNA-synt_2d CMS1_k127_4733790_5 224911.27354078 6.816e-49 179.0 28NKC@1|root,2ZBM7@2|Bacteria,1MWMY@1224|Proteobacteria,2TU05@28211|Alphaproteobacteria,3JS0Z@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - MA20_08580 - - - - - - - - - - - Endostatin CMS1_k127_4733790_4 113395.AXAI01000019_gene6165 1.739e-57 208.0 COG1917@1|root,COG1917@2|Bacteria,1RH1V@1224|Proteobacteria,2U990@28211|Alphaproteobacteria,3JYQR@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S AraC-like ligand binding domain MA20_13155 - - - - - - - - - - - Cupin_2 CMS1_k127_4733790_8 1089552.KI911559_gene624 8.75e-28 115.0 COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2UF6W@28211|Alphaproteobacteria,2JTV9@204441|Rhodospirillales 204441|Rhodospirillales K Cold shock - - - ko:K03704 - - - - ko00000,ko03000 - - - CSD CMS1_k127_4733790_11 1054213.HMPREF9946_05302 0.0001568 48.0 COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,2TRMJ@28211|Alphaproteobacteria,2JPN7@204441|Rhodospirillales 204441|Rhodospirillales L ATP-dependent helicase hrpB - 3.6.4.13 ko:K03579 - - - - ko00000,ko01000 - - - DEAD,HA2,Helicase_C,HrpB_C CMS1_k127_4733790_0 1187851.A33M_4462 0.0 1095.0 COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,3FDRR@34008|Rhodovulum 28211|Alphaproteobacteria T His Kinase A (phosphoacceptor) domain cckA - 2.7.13.3 ko:K13587 ko02020,ko04112,map02020,map04112 M00512 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,Response_reg CMS1_k127_4733790_1 1038866.KB902809_gene2490 1.182e-140 454.0 COG1377@1|root,COG1377@2|Bacteria,1MUWI@1224|Proteobacteria,2TS13@28211|Alphaproteobacteria,3JRW6@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin flhB - - ko:K02401 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - Bac_export_2 CMS1_k127_4733790_2 1429916.X566_24445 1.044e-100 335.0 COG1684@1|root,COG1684@2|Bacteria,1NIF4@1224|Proteobacteria,2TTHN@28211|Alphaproteobacteria,3JVDK@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria N Role in flagellar biosynthesis fliR - - ko:K02421 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - Bac_export_1 CMS1_k127_4733790_9 1187851.A33M_1525 7.624e-27 118.0 COG1987@1|root,COG1987@2|Bacteria,1N73W@1224|Proteobacteria,2UBX6@28211|Alphaproteobacteria,3FDGH@34008|Rhodovulum 28211|Alphaproteobacteria N Bacterial export proteins, family 3 fliQ - - ko:K02420 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2 - - Bac_export_3 CMS1_k127_4733790_10 1304878.AUGD01000009_gene6369 1.334e-21 97.0 COG1677@1|root,COG1677@2|Bacteria,1QFE1@1224|Proteobacteria,2V5VZ@28211|Alphaproteobacteria,3JZEN@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria N Flagellar hook-basal body complex protein FliE fliE - - ko:K02408 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - FliE CMS1_k127_4733790_3 1429916.X566_24460 1.399e-62 217.0 COG1558@1|root,COG1558@2|Bacteria,1RHI3@1224|Proteobacteria,2U94I@28211|Alphaproteobacteria,3JY7J@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria N Belongs to the flagella basal body rod proteins family flgC - - ko:K02388 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C CMS1_k127_4733790_7 1197906.CAJQ02000043_gene1921 2.088e-39 151.0 COG1815@1|root,COG1815@2|Bacteria,1N1G1@1224|Proteobacteria,2UCJ4@28211|Alphaproteobacteria,3JY2R@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body flgB - - ko:K02387 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod CMS1_k127_4733790_6 1038860.AXAP01000011_gene184 5.399e-46 175.0 COG3115@1|root,COG3115@2|Bacteria,1N9KJ@1224|Proteobacteria,2TUCT@28211|Alphaproteobacteria,3JSXR@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria D Flagellar biosynthesis protein, FliO - - - - - - - - - - - - FliO CMS1_k127_4744537_0 1336243.JAEA01000010_gene3414 0.0 1666.0 COG1014@1|root,COG4231@1|root,COG1014@2|Bacteria,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,2TSHH@28211|Alphaproteobacteria,1JTYW@119045|Methylobacteriaceae 28211|Alphaproteobacteria C PFAM pyruvate ferredoxin flavodoxin oxidoreductase - - 1.2.7.8 ko:K04090 - - - - br01601,ko00000,ko01000 - - - POR,TPP_enzyme_C CMS1_k127_4744537_1 1211115.ALIQ01000225_gene1814 0.0 1062.0 COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,2TSSI@28211|Alphaproteobacteria 28211|Alphaproteobacteria I COG1022 Long-chain acyl-CoA synthetases (AMP-forming) fadD3 - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding CMS1_k127_4744537_2 1411123.JQNH01000001_gene673 3.436e-44 164.0 COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,2TQK1@28211|Alphaproteobacteria 28211|Alphaproteobacteria E branched-chain amino acid cysA - - ko:K01995,ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C CMS1_k127_4750278_0 1123392.AQWL01000001_gene1447 3.046e-119 386.0 COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,2VH4U@28216|Betaproteobacteria,1KS6G@119069|Hydrogenophilales 119069|Hydrogenophilales E lysine 2,3-aminomutase - - - - - - - - - - - - - CMS1_k127_4750278_1 1123393.KB891327_gene498 5.744e-79 268.0 COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,2VPHG@28216|Betaproteobacteria,1KSHV@119069|Hydrogenophilales 119069|Hydrogenophilales S Sulfatase-modifying factor enzyme 1 - - - - - - - - - - - - FGE-sulfatase CMS1_k127_4758053_0 1049564.TevJSym_au00430 1.087e-119 396.0 COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,1RMFZ@1236|Gammaproteobacteria,1J524@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) mltD GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008932,GO:0008933,GO:0009893,GO:0016020,GO:0016740,GO:0016757,GO:0019222,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043085,GO:0044093,GO:0044464,GO:0048518,GO:0050789,GO:0050790,GO:0051341,GO:0051353,GO:0061783,GO:0065007,GO:0065009 - ko:K08307 - - - - ko00000,ko01000,ko01011 - - - LysM,SLT CMS1_k127_4758053_1 1266925.JHVX01000010_gene1321 1.926e-58 204.0 COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2VH5T@28216|Betaproteobacteria,372B6@32003|Nitrosomonadales 28216|Betaproteobacteria P Belongs to the ABC transporter superfamily dppF - - ko:K02031,ko:K02032 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,oligo_HPY CMS1_k127_475813_2 709797.CSIRO_1019 3.989e-15 75.0 COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,2TRZZ@28211|Alphaproteobacteria,3JQPP@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate folD GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 - - - THF_DHG_CYH,THF_DHG_CYH_C CMS1_k127_475813_0 1187851.A33M_1324 2.238e-89 297.0 COG0521@1|root,COG0521@2|Bacteria,1R9W2@1224|Proteobacteria,2TTA8@28211|Alphaproteobacteria,3FD22@34008|Rhodovulum 28211|Alphaproteobacteria H May be involved in the biosynthesis of molybdopterin moaB GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0042802,GO:0044424,GO:0044444,GO:0044464 2.7.7.75 ko:K03638 ko00790,ko01100,map00790,map01100 - R09726 RC00002 ko00000,ko00001,ko01000 - - - MoCF_biosynth CMS1_k127_475813_1 1187851.A33M_1325 4.071e-89 298.0 COG2321@1|root,COG2321@2|Bacteria,1MU4U@1224|Proteobacteria,2TRCS@28211|Alphaproteobacteria,3FE2G@34008|Rhodovulum 28211|Alphaproteobacteria S Putative neutral zinc metallopeptidase - - - ko:K07054 - - - - ko00000 - - - Zn_peptidase CMS1_k127_4761551_6 622637.KE124774_gene3177 8.726e-09 57.0 COG0087@1|root,COG0087@2|Bacteria,1MUST@1224|Proteobacteria,2TRHB@28211|Alphaproteobacteria,36XCX@31993|Methylocystaceae 28211|Alphaproteobacteria J Ribosomal protein L3 rplC - - ko:K02906 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L3 CMS1_k127_4761551_5 1122963.AUHB01000009_gene1928 9.255e-58 201.0 COG0051@1|root,COG0051@2|Bacteria,1RGWF@1224|Proteobacteria,2U95D@28211|Alphaproteobacteria,36YEW@31993|Methylocystaceae 28211|Alphaproteobacteria J Ribosomal protein S10p/S20e rpsJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02946 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S10 CMS1_k127_4761551_1 1187851.A33M_2385 1.528e-246 762.0 COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,2TQP8@28211|Alphaproteobacteria,3FCNI@34008|Rhodovulum 28211|Alphaproteobacteria J GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis tuf GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K02358 - - - - ko00000,ko03012,ko03029,ko04147 - - - GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 CMS1_k127_4761551_0 316058.RPB_2292 0.0 1255.0 COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,2TQVI@28211|Alphaproteobacteria,3JS6N@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome fusA - - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 CMS1_k127_4761551_3 504832.OCAR_5673 1.594e-84 281.0 COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,2TSI8@28211|Alphaproteobacteria,3JS8U@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA rpsG GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02992 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S7 CMS1_k127_4761551_4 639283.Snov_1443 3.34e-68 232.0 COG0048@1|root,COG0048@2|Bacteria,1RCWY@1224|Proteobacteria,2U70K@28211|Alphaproteobacteria,3EZBU@335928|Xanthobacteraceae 28211|Alphaproteobacteria J 30S ribosomal protein S12 rpsL GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02950 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosom_S12_S23 CMS1_k127_4761551_2 1187851.A33M_2391 3.03e-87 291.0 COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,2TRHV@28211|Alphaproteobacteria,3FCU5@34008|Rhodovulum 28211|Alphaproteobacteria K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03046,ko:K13797 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 CMS1_k127_479040_2 426117.M446_1935 9.031e-205 645.0 COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,2TQZ6@28211|Alphaproteobacteria,1JUIC@119045|Methylobacteriaceae 28211|Alphaproteobacteria EQ PFAM Hydantoinase oxoprolinase hyuA - 3.5.2.14 ko:K01473 ko00330,ko01100,map00330,map01100 - R03187 RC00632 ko00000,ko00001,ko01000 - - - Hydant_A_N,Hydantoinase_A CMS1_k127_479040_0 670292.JH26_14115 3.327e-287 896.0 COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,2TVYU@28211|Alphaproteobacteria,1JWYY@119045|Methylobacteriaceae 28211|Alphaproteobacteria EQ Hydantoinase B oxoprolinase hyuB - 3.5.2.14 ko:K01474 ko00330,ko01100,map00330,map01100 - R03187 RC00632 ko00000,ko00001,ko01000 - - - Hydantoinase_B CMS1_k127_479040_4 670292.JH26_14120 1.655e-122 399.0 COG2513@1|root,COG2513@2|Bacteria,1N4VT@1224|Proteobacteria,2TTP8@28211|Alphaproteobacteria,1JVBX@119045|Methylobacteriaceae 28211|Alphaproteobacteria G Isocitrate lyase family prpB - - - - - - - - - - - PEP_mutase CMS1_k127_479040_7 426117.M446_1931 9.285e-94 315.0 COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2TSCA@28211|Alphaproteobacteria,1JZCQ@119045|Methylobacteriaceae 28211|Alphaproteobacteria E ATPases associated with a variety of cellular activities - - - ko:K01996,ko:K11958 ko02010,ko02024,map02010,map02024 M00237,M00322 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4,3.A.1.4.2,3.A.1.4.6 - - ABC_tran CMS1_k127_479040_8 1123060.JONP01000006_gene4748 6.776e-92 309.0 COG0411@1|root,COG0411@2|Bacteria,1MUFT@1224|Proteobacteria,2U22X@28211|Alphaproteobacteria,2JS5W@204441|Rhodospirillales 204441|Rhodospirillales E Branched-chain amino acid ATP-binding cassette transporter - - - - - - - - - - - - ABC_tran,BCA_ABC_TP_C CMS1_k127_479040_6 1123229.AUBC01000015_gene4638 5.459e-117 394.0 COG4177@1|root,COG4177@2|Bacteria,1MU52@1224|Proteobacteria,2TSUI@28211|Alphaproteobacteria,3JWHR@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 CMS1_k127_479040_5 670292.JH26_14145 3.327e-121 396.0 COG0559@1|root,COG0559@2|Bacteria,1N5XH@1224|Proteobacteria,2TSH5@28211|Alphaproteobacteria,1JUV9@119045|Methylobacteriaceae 28211|Alphaproteobacteria E Belongs to the binding-protein-dependent transport system permease family - - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 CMS1_k127_479040_3 358220.C380_11740 2.236e-167 542.0 COG0683@1|root,COG0683@2|Bacteria,1MWQB@1224|Proteobacteria,2VJ1E@28216|Betaproteobacteria,4ACV2@80864|Comamonadaceae 28216|Betaproteobacteria E Extracellular liganD-binding receptor - - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 CMS1_k127_479040_10 438753.AZC_2108 3.641e-78 271.0 COG2188@1|root,COG2188@2|Bacteria,1MX3T@1224|Proteobacteria,2TVD7@28211|Alphaproteobacteria,3F29W@335928|Xanthobacteraceae 28211|Alphaproteobacteria K UTRA - - - ko:K03710 - - - - ko00000,ko03000 - - - GntR,UTRA CMS1_k127_479040_1 1038858.AXBA01000003_gene4261 3.395e-225 709.0 COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,2TVD2@28211|Alphaproteobacteria,3F29C@335928|Xanthobacteraceae 28211|Alphaproteobacteria E Aconitase family (aconitate hydratase) leuC3 - 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase CMS1_k127_479040_11 438753.AZC_2107 1.009e-63 224.0 COG0066@1|root,COG0066@2|Bacteria,1REBS@1224|Proteobacteria,2U7SV@28211|Alphaproteobacteria,3F28A@335928|Xanthobacteraceae 28211|Alphaproteobacteria E Aconitase C-terminal domain - - 4.2.1.33,4.2.1.35 ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R10170 RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase_C CMS1_k127_479040_9 1187851.A33M_0109 8.52e-80 276.0 COG5607@1|root,COG5607@2|Bacteria,1Q6AR@1224|Proteobacteria,2VCGI@28211|Alphaproteobacteria,3FEJI@34008|Rhodovulum 28211|Alphaproteobacteria S CHAD - - - - - - - - - - - - CHAD CMS1_k127_479040_13 1348338.ADILRU_1290 1.346e-40 165.0 28MZG@1|root,2ZB66@2|Bacteria 2|Bacteria S OsmC-like protein - - - - - - - - - - - - OsmC CMS1_k127_479040_12 573370.DMR_03420 3.937e-41 152.0 2AU0F@1|root,31JKB@2|Bacteria,1RGGF@1224|Proteobacteria,42S33@68525|delta/epsilon subdivisions,2WNKG@28221|Deltaproteobacteria,2MC3F@213115|Desulfovibrionales 28221|Deltaproteobacteria S COG NOG14600 non supervised orthologous group - - - - - - - - - - - - - CMS1_k127_4791107_2 1120792.JAFV01000001_gene381 2.705e-101 340.0 COG0491@1|root,COG0491@2|Bacteria,1MY6G@1224|Proteobacteria,2TTBX@28211|Alphaproteobacteria,370FP@31993|Methylocystaceae 28211|Alphaproteobacteria S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B CMS1_k127_4791107_0 1038859.AXAU01000007_gene5750 1.659e-193 629.0 COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,2TX02@28211|Alphaproteobacteria,3JUXU@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H TonB dependent receptor - - - ko:K02014 - - - - ko00000,ko02000 1.B.14 - - Plug,TonB_dep_Rec CMS1_k127_4791107_5 398525.KB900701_gene5849 1.19e-36 145.0 COG0457@1|root,COG0457@2|Bacteria,1R718@1224|Proteobacteria,2U3AD@28211|Alphaproteobacteria,3JWC5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_2 CMS1_k127_4791107_4 1187851.A33M_2475 5.75e-37 143.0 COG1324@1|root,COG1324@2|Bacteria,1Q6BZ@1224|Proteobacteria,2VCHQ@28211|Alphaproteobacteria,3FEJZ@34008|Rhodovulum 28211|Alphaproteobacteria P CutA1 divalent ion tolerance protein - - - ko:K03926 - - - - ko00000 - - - CutA1 CMS1_k127_4791107_1 323098.Nwi_1335 1.035e-118 386.0 COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,2TSKN@28211|Alphaproteobacteria,3JUS0@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP nadK - 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 - R00104 RC00002,RC00078 ko00000,ko00001,ko01000 - - - NAD_kinase CMS1_k127_4791107_3 1028801.RG1141_PA14110 1.409e-50 182.0 COG2080@1|root,COG2080@2|Bacteria,1N1KQ@1224|Proteobacteria,2U2YE@28211|Alphaproteobacteria,4BFP7@82115|Rhizobiaceae 28211|Alphaproteobacteria C [2Fe-2S] binding domain - - 1.17.2.1 ko:K18029 ko00760,ko01120,map00760,map01120 M00622 R09473 RC00589 ko00000,ko00001,ko00002,ko01000 - - - Fer2,Fer2_2 CMS1_k127_4798892_0 1298867.AUES01000137_gene4645 1.358e-165 533.0 COG3547@1|root,COG3547@2|Bacteria,1MW0N@1224|Proteobacteria,2TUGE@28211|Alphaproteobacteria,3JX5I@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L PFAM transposase IS116 IS110 IS902 family - - - ko:K07486 - - - - ko00000 - - - DEDD_Tnp_IS110,Transposase_20 CMS1_k127_4805913_1 1038858.AXBA01000028_gene1008 4.077e-108 362.0 COG0726@1|root,COG0726@2|Bacteria,1MV3V@1224|Proteobacteria,2TR0I@28211|Alphaproteobacteria,3F0MK@335928|Xanthobacteraceae 28211|Alphaproteobacteria G Polysaccharide deacetylase - - - - - - - - - - - - Polysacc_deac_1 CMS1_k127_4805913_0 1205680.CAKO01000038_gene1894 1.278e-138 459.0 COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2TUKZ@28211|Alphaproteobacteria,2JS3D@204441|Rhodospirillales 204441|Rhodospirillales J Amidase - - - - - - - - - - - - Amidase CMS1_k127_4805913_2 709797.CSIRO_2436 3.356e-06 51.0 COG0477@1|root,COG2814@2|Bacteria,1MVHG@1224|Proteobacteria,2TRA4@28211|Alphaproteobacteria,3JSPN@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria EGP Major Facilitator Superfamily MA20_36250 - - - - - - - - - - - MFS_1 CMS1_k127_4805922_0 1380394.JADL01000005_gene5609 1.323e-313 968.0 COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,2TVZI@28211|Alphaproteobacteria,2JQ15@204441|Rhodospirillales 204441|Rhodospirillales C Formate dehydrogenase subunit alpha - - - - - - - - - - - - Fer2_4,Fer4_7,Fer4_9,Molybdop_Fe4S4,Molybdopterin,Molydop_binding CMS1_k127_4808569_0 323097.Nham_2723 5.801e-115 379.0 COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,2TR8Z@28211|Alphaproteobacteria,3JT2U@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 - R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 - - - IPPT CMS1_k127_4808569_2 1122951.ATUE01000006_gene1057 1.883e-17 89.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,3NPQ1@468|Moraxellaceae 1236|Gammaproteobacteria NT PAS fold - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal,PAS_3,PAS_9 CMS1_k127_4808569_1 1187851.A33M_1920 4.337e-95 314.0 COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2TR1I@28211|Alphaproteobacteria,3FCQM@34008|Rhodovulum 28211|Alphaproteobacteria EH Thiamine pyrophosphate enzyme, N-terminal TPP binding domain ilvI - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N CMS1_k127_481071_5 196162.Noca_4459 5.294e-88 295.0 COG2128@1|root,COG2128@2|Bacteria,2HZX3@201174|Actinobacteria,4DUDY@85009|Propionibacteriales 201174|Actinobacteria S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - - - - - - - - - - - CMS1_k127_481071_4 28444.JODQ01000007_gene5917 1.099e-89 308.0 COG1116@1|root,COG1116@2|Bacteria,2GN33@201174|Actinobacteria,4EGTJ@85012|Streptosporangiales 201174|Actinobacteria P ATPases associated with a variety of cellular activities - - - ko:K02049 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - AAA_assoc_C,ABC_tran CMS1_k127_481071_2 1120983.KB894571_gene2468 1.191e-120 405.0 COG1073@1|root,COG1073@2|Bacteria,1PJHR@1224|Proteobacteria,2U2QB@28211|Alphaproteobacteria 28211|Alphaproteobacteria S alpha beta - - - - - - - - - - - - - CMS1_k127_481071_3 397278.JOJN01000005_gene774 8.557e-93 317.0 COG0006@1|root,COG0006@2|Bacteria 2|Bacteria E proline dipeptidase activity - - 3.4.11.9 ko:K01262 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 CMS1_k127_481071_0 748247.AZKH_1924 7.498e-195 617.0 COG0015@1|root,COG0015@2|Bacteria,1MXNN@1224|Proteobacteria,2VID3@28216|Betaproteobacteria 28216|Betaproteobacteria F 3-carboxy-cis,cis-muconate cycloisomerase - - 5.5.1.2 ko:K01857 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 - R03307 RC00902 ko00000,ko00001,ko01000 - - - ADSL_C,Lyase_1 CMS1_k127_481071_1 1187851.A33M_2472 2.906e-141 462.0 COG0204@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,1MWDY@1224|Proteobacteria,2TTGI@28211|Alphaproteobacteria 28211|Alphaproteobacteria IQ Major facilitator Superfamily aas - 2.3.1.40,6.2.1.20 ko:K05939 ko00071,ko00564,map00071,map00564 - R01406,R04864 RC00014,RC00039,RC00041 ko00000,ko00001,ko01000 - - - AMP-binding,Acyltransferase,MFS_1 CMS1_k127_4817889_4 1380355.JNIJ01000011_gene960 1.318e-36 139.0 COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria,2U24Y@28211|Alphaproteobacteria,3JXTX@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L Integrase - - - - - - - - - - - - HTH_32,rve,rve_3 CMS1_k127_4817889_3 1380355.JNIJ01000041_gene5260 2.32e-131 427.0 COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria,2U24Y@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Integrase - - - - - - - - - - - - HTH_32,rve,rve_3 CMS1_k127_4817889_0 663610.JQKO01000007_gene2306 1.603e-319 984.0 COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2TRKS@28211|Alphaproteobacteria,3N9Z2@45404|Beijerinckiaceae 28211|Alphaproteobacteria I Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA - - 6.2.1.1,6.2.1.16 ko:K01895,ko:K01907 ko00010,ko00280,ko00620,ko00640,ko00650,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00280,map00620,map00640,map00650,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354,R01357 RC00004,RC00012,RC00014,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C CMS1_k127_4817889_1 663610.JQKO01000007_gene2307 2.903e-178 562.0 COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,2TRSS@28211|Alphaproteobacteria,3NACS@45404|Beijerinckiaceae 28211|Alphaproteobacteria C Dehydrogenase E1 component acoA - 1.2.4.1,1.2.4.4 ko:K00161,ko:K00166,ko:K21416 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00036,M00307 R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh,OxoDH_E1alpha_N CMS1_k127_4817889_2 663610.JQKO01000007_gene2308 6.306e-154 493.0 COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,2TRFK@28211|Alphaproteobacteria,3NCZ8@45404|Beijerinckiaceae 28211|Alphaproteobacteria C Transketolase, pyrimidine binding domain - - 1.2.4.1 ko:K00162,ko:K21417 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C CMS1_k127_4822193_17 426117.M446_2825 3.413e-12 70.0 COG0475@1|root,COG0589@1|root,COG0475@2|Bacteria,COG0589@2|Bacteria,1MVGV@1224|Proteobacteria,2TUCH@28211|Alphaproteobacteria,1JXK8@119045|Methylobacteriaceae 28211|Alphaproteobacteria PT PFAM UspA domain protein - - - - - - - - - - - - Na_H_Exchanger,Usp CMS1_k127_4822193_3 288000.BBta_1556 4.856e-195 617.0 COG1914@1|root,COG1914@2|Bacteria,1MW6X@1224|Proteobacteria,2TUTC@28211|Alphaproteobacteria,3JX8F@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P Natural resistance-associated macrophage protein mntH - - ko:K03322 - - - - ko00000,ko02000 2.A.55.2.6,2.A.55.3 - - Nramp CMS1_k127_4822193_7 709797.CSIRO_3306 1.404e-131 422.0 COG2935@1|root,COG2935@2|Bacteria,1MW62@1224|Proteobacteria,2TQY8@28211|Alphaproteobacteria,3JUT3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate ate GO:0003674,GO:0003824,GO:0004057,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016598,GO:0016740,GO:0016746,GO:0016755,GO:0019538,GO:0019941,GO:0030163,GO:0036211,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 2.3.2.29 ko:K21420 - - R11547,R11548 RC00064 ko00000,ko01000 - - - ATE_C,ATE_N CMS1_k127_4822193_14 288000.BBta_4656 1.443e-65 228.0 COG1714@1|root,COG1714@2|Bacteria,1P9TI@1224|Proteobacteria,2TRIS@28211|Alphaproteobacteria,3JQUB@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S RDD family MA20_36685 - - - - - - - - - - - RDD CMS1_k127_4822193_4 1187851.A33M_2535 8.159e-184 584.0 COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2TQN9@28211|Alphaproteobacteria,3FE9G@34008|Rhodovulum 28211|Alphaproteobacteria E Pyridoxal-phosphate dependent enzyme ilvA - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - ACT,ACT_4,PALP CMS1_k127_4822193_0 1205680.CAKO01000014_gene92 1.102e-250 795.0 COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TQMW@28211|Alphaproteobacteria,2JW0J@204441|Rhodospirillales 204441|Rhodospirillales C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - - - - - - - - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 CMS1_k127_4822193_5 1429916.X566_21965 3.107e-180 569.0 COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,2TS3F@28211|Alphaproteobacteria,3JRDV@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H Belongs to the ALAD family hemB GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00036 RC00918,RC01781 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ALAD CMS1_k127_4822193_2 1429916.X566_04165 6.474e-197 620.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TQKE@28211|Alphaproteobacteria,3JRHU@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I acyl-CoA dehydrogenase MA20_27425 - 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N CMS1_k127_4822193_13 1247726.MIM_c01680 8.487e-69 246.0 COG0662@1|root,COG0662@2|Bacteria 2|Bacteria G Cupin 2, conserved barrel domain protein - - - - - - - - - - - - - CMS1_k127_4822193_9 1411123.JQNH01000001_gene1241 1.304e-117 390.0 COG1024@1|root,COG1024@2|Bacteria,1MU0B@1224|Proteobacteria,2TQW3@28211|Alphaproteobacteria 28211|Alphaproteobacteria I enoyl-CoA hydratase hibch - 3.1.2.4,4.2.1.17 ko:K01692,ko:K05605 ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01200,map01212 M00013,M00032,M00087 R03026,R03045,R03158,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05064,R05595,R06411,R06412,R06942,R08093 RC00004,RC00014,RC00137,RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - - ECH_2 CMS1_k127_4822193_16 652103.Rpdx1_2791 2.563e-40 156.0 2D2F3@1|root,32TCM@2|Bacteria,1NECH@1224|Proteobacteria,2U5FZ@28211|Alphaproteobacteria,3JYBV@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - MA20_36695 - - - - - - - - - - - - CMS1_k127_4822193_8 1429916.X566_04160 6.5e-125 406.0 COG2084@1|root,COG2084@2|Bacteria,1RA7F@1224|Proteobacteria,2UVAZ@28211|Alphaproteobacteria,3JRFH@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Belongs to the 3-hydroxyisobutyrate dehydrogenase family mmsB - 1.1.1.31 ko:K00020 ko00280,ko01100,map00280,map01100 - R05066 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 CMS1_k127_4822193_10 1187851.A33M_2425 4.535e-91 301.0 COG1846@1|root,COG1846@2|Bacteria,1RA1V@1224|Proteobacteria,2U5W6@28211|Alphaproteobacteria,3FD4R@34008|Rhodovulum 28211|Alphaproteobacteria K Winged helix DNA-binding domain mucS - - - - - - - - - - - HTH_27 CMS1_k127_4822193_1 78245.Xaut_4276 1.605e-224 705.0 COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,2TQKT@28211|Alphaproteobacteria,3EY12@335928|Xanthobacteraceae 28211|Alphaproteobacteria E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism glyA - 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 - - - SHMT CMS1_k127_4822193_11 1245469.S58_33180 2.56e-78 268.0 COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,2U75W@28211|Alphaproteobacteria,3JVH1@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes nrdR - - ko:K07738 - - - - ko00000,ko03000 - - - ATP-cone CMS1_k127_4822193_6 1187851.A33M_4044 7.546e-134 445.0 COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,2TR70@28211|Alphaproteobacteria,3FCTK@34008|Rhodovulum 28211|Alphaproteobacteria F Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate ribD - 1.1.1.193,3.5.4.26 ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 M00125 R03458,R03459 RC00204,RC00933 ko00000,ko00001,ko00002,ko01000 - - - RibD_C,dCMP_cyt_deam_1 CMS1_k127_4822193_12 1187851.A33M_1908 9.681e-78 267.0 COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,2U3RS@28211|Alphaproteobacteria,3FD6G@34008|Rhodovulum 28211|Alphaproteobacteria H Lumazine binding domain ribE GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00066 RC00958,RC00960 ko00000,ko00001,ko00002,ko01000 - - - Lum_binding CMS1_k127_4822193_15 394.NGR_c09640 4.834e-48 177.0 COG0054@1|root,COG0054@2|Bacteria,1RD9J@1224|Proteobacteria,2U9IZ@28211|Alphaproteobacteria,4BEB3@82115|Rhizobiaceae 28211|Alphaproteobacteria H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin ribH GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R04457 RC00960 ko00000,ko00001,ko00002,ko01000 - - - DMRL_synthase CMS1_k127_4822363_5 1211115.ALIQ01000183_gene2912 6.869e-33 129.0 COG5470@1|root,COG5470@2|Bacteria,1N012@1224|Proteobacteria,2VG1G@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Domain of unknown function (DUF1330) - - - - - - - - - - - - DUF1330 CMS1_k127_4822363_0 1038859.AXAU01000004_gene4595 1.938e-160 517.0 COG0477@1|root,COG0477@2|Bacteria,1QTUM@1224|Proteobacteria,2TVX9@28211|Alphaproteobacteria,3K6WB@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1,Sugar_tr CMS1_k127_4822363_4 1297863.APJF01000013_gene3973 5.975e-39 151.0 COG0741@1|root,COG0741@2|Bacteria,1N08U@1224|Proteobacteria,2U82R@28211|Alphaproteobacteria,3JVY0@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Transglycosylase SLT domain - - - - - - - - - - - - SLT CMS1_k127_4822363_1 316058.RPB_3105 1.014e-123 404.0 COG2159@1|root,COG2159@2|Bacteria,1MXI7@1224|Proteobacteria,2U15G@28211|Alphaproteobacteria,3JVRP@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Amidohydrolase - - 4.1.1.103,4.1.1.46 ko:K07045,ko:K14333,ko:K15063,ko:K20941 ko00362,ko00627,ko01120,map00362,map00627,map01120 - R00821,R09278,R11353 RC00390,RC00569 ko00000,ko00001,ko01000 - - - Amidohydro_2 CMS1_k127_4822363_2 1297865.APJD01000009_gene2886 8.316e-59 206.0 COG1376@1|root,COG1376@2|Bacteria,1MVYT@1224|Proteobacteria,2U60K@28211|Alphaproteobacteria,3JQSZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ErfK YbiS YcfS YnhG - - - - - - - - - - - - YkuD CMS1_k127_4823528_1 1211115.ALIQ01000213_gene2522 1.665e-72 256.0 COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,2TTQC@28211|Alphaproteobacteria,3NA7Y@45404|Beijerinckiaceae 28211|Alphaproteobacteria J RNA pseudouridylate synthase rluC GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.24 ko:K06179 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 CMS1_k127_4823528_0 1040989.AWZU01000014_gene4509 1.791e-107 349.0 COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,2TQVF@28211|Alphaproteobacteria,3JSFI@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L AAA C-terminal domain rarA GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0030894,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - ko:K07478 - - - - ko00000 - - - AAA,AAA_assoc_2,MgsA_C,RuvB_N CMS1_k127_482366_5 864069.MicloDRAFT_00040990 5.861e-78 271.0 COG3836@1|root,COG3836@2|Bacteria,1MUSG@1224|Proteobacteria,2TT2W@28211|Alphaproteobacteria,1JSYG@119045|Methylobacteriaceae 28211|Alphaproteobacteria G Belongs to the HpcH HpaI aldolase family - - 4.1.2.20,4.1.2.52 ko:K01630,ko:K02510 ko00053,ko00350,ko01120,map00053,map00350,map01120 - R01645,R01647,R02754,R03277 RC00307,RC00435,RC00572,RC00574,RC03057 ko00000,ko00001,ko01000 - - - HpcH_HpaI CMS1_k127_482366_2 1038867.AXAY01000015_gene6941 1.347e-113 372.0 COG3971@1|root,COG3971@2|Bacteria,1MVVV@1224|Proteobacteria,2TUWC@28211|Alphaproteobacteria,3K2R0@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria Q Fumarylacetoacetate (FAA) hydrolase family hpcG - - ko:K02509 ko00350,ko01120,map00350,map01120 - R04132,R06897 RC01615,RC02595 ko00000,ko00001,ko01000 - - - FAA_hydrolase CMS1_k127_482366_7 414684.RC1_2465 2.58e-17 84.0 2DNNN@1|root,32YAU@2|Bacteria,1NA5K@1224|Proteobacteria,2UFEY@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_482366_3 1429916.X566_13900 2.043e-113 376.0 COG2057@1|root,COG2057@2|Bacteria,1RA4V@1224|Proteobacteria,2TQS5@28211|Alphaproteobacteria,3JRZ2@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Coenzyme A transferase scoB - 2.8.3.5 ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 - R00410 RC00014 ko00000,ko00001,ko01000 - - - CoA_trans CMS1_k127_482366_1 1502851.FG93_06110 3.108e-122 395.0 COG1788@1|root,COG1788@2|Bacteria,1MVEI@1224|Proteobacteria,2TTE6@28211|Alphaproteobacteria,3JRJ3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Coenzyme A transferase scoA - 2.8.3.5 ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 - R00410 RC00014 ko00000,ko00001,ko01000 - - - CoA_trans CMS1_k127_482366_4 1123060.JONP01000011_gene3085 2.407e-80 280.0 COG0111@1|root,COG0111@2|Bacteria,1MW1U@1224|Proteobacteria,2TSUU@28211|Alphaproteobacteria,2JWNR@204441|Rhodospirillales 204441|Rhodospirillales EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - - - - - - - - - - 2-Hacid_dh_C CMS1_k127_482366_0 1123060.JONP01000011_gene3084 1.265e-175 562.0 COG0006@1|root,COG0006@2|Bacteria,1R7EI@1224|Proteobacteria 1224|Proteobacteria E peptidase, M24 - - - - - - - - - - - - Creatinase_N,Peptidase_M24 CMS1_k127_482366_6 1057002.KB905371_gene17 1.388e-51 188.0 COG0251@1|root,COG0251@2|Bacteria 2|Bacteria J oxidation-reduction process - - - - - - - - - - - - Ribonuc_L-PSP CMS1_k127_4843017_0 1163617.SCD_n02918 5.237e-118 394.0 COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,2VHG1@28216|Betaproteobacteria 28216|Betaproteobacteria MU type I secretion outer membrane protein, TolC - - - ko:K12340 ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133 M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821 - - ko00000,ko00001,ko00002,ko01504,ko02000,ko02044 1.B.17,2.A.6.2 - - OEP CMS1_k127_4843017_1 570967.JMLV01000001_gene2627 6.44e-43 160.0 COG3146@1|root,COG3146@2|Bacteria,1MU35@1224|Proteobacteria,2TS5I@28211|Alphaproteobacteria,2JPA3@204441|Rhodospirillales 204441|Rhodospirillales S Peptidogalycan biosysnthesis/recognition - - - ko:K09919 - - - - ko00000 - - - FemAB_like CMS1_k127_4864882_3 1125973.JNLC01000017_gene3604 1.447e-23 99.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQW2@28211|Alphaproteobacteria,3JT3A@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Sigma-54 interaction domain ntrX - - ko:K13599 ko02020,map02020 M00498 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat CMS1_k127_4864882_1 1187851.A33M_2256 1.452e-115 381.0 COG0115@1|root,COG0115@2|Bacteria,1MVAT@1224|Proteobacteria,2TR7R@28211|Alphaproteobacteria,3FD0A@34008|Rhodovulum 28211|Alphaproteobacteria EH Amino-transferase class IV dat GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016769,GO:0019478,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046416,GO:0046437,GO:0047810,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.6.1.21 ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 - R01148,R01582,R02459,R02851,R02924,R05053 RC00006,RC00008,RC00025 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_4 CMS1_k127_4864882_2 1125973.JNLC01000017_gene3608 3.744e-44 163.0 COG1923@1|root,COG1923@2|Bacteria,1MZM1@1224|Proteobacteria,2UBTW@28211|Alphaproteobacteria,3JZC3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs hfq GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0006807,GO:0008150,GO:0008152,GO:0009399,GO:0071941,GO:0097159,GO:1901363 - ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 - - - ko00000,ko00001,ko03019,ko03036 - - - Hfq CMS1_k127_4864882_0 1187851.A33M_2258 7.227e-189 599.0 COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,2TUXJ@28211|Alphaproteobacteria,3FCIU@34008|Rhodovulum 28211|Alphaproteobacteria S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis hflX GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006464,GO:0006468,GO:0006518,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006996,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018105,GO:0018193,GO:0018209,GO:0019001,GO:0019222,GO:0019538,GO:0019843,GO:0022411,GO:0030554,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0032790,GO:0032984,GO:0032988,GO:0034248,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0036211,GO:0036289,GO:0043021,GO:0043022,GO:0043023,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:2000112 - ko:K03665 - - - - ko00000,ko03009 - - - GTP-bdg_M,GTP-bdg_N,MMR_HSR1 CMS1_k127_4865537_3 316058.RPB_3428 1.151e-21 94.0 COG3181@1|root,COG3181@2|Bacteria,1MXEX@1224|Proteobacteria,2TT5Y@28211|Alphaproteobacteria,3JUU2@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter family receptor MA20_15115 - - ko:K07795 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctC CMS1_k127_4865537_1 639283.Snov_3396 1.961e-48 178.0 2BKYI@1|root,32FF5@2|Bacteria,1RB6X@1224|Proteobacteria,2VER9@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter TctB family MA20_15120 - - - - - - - - - - - TctB CMS1_k127_4865537_0 316055.RPE_1955 8.868e-278 859.0 COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2TR4Q@28211|Alphaproteobacteria,3JVYZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter TctA family MA20_15125 - - ko:K07793 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.80.1 - - TctA CMS1_k127_4865537_2 1168059.KB899087_gene3933 8.167e-23 103.0 COG1802@1|root,COG1802@2|Bacteria,1MXNF@1224|Proteobacteria,2UPIM@28211|Alphaproteobacteria,3F0W7@335928|Xanthobacteraceae 28211|Alphaproteobacteria K FCD - - - - - - - - - - - - FCD,GntR CMS1_k127_4884145_3 1187851.A33M_0092 1.165e-24 110.0 COG3090@1|root,COG3090@2|Bacteria,1QYHJ@1224|Proteobacteria,2UI8I@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Tripartite ATP-independent periplasmic transporters, DctQ component - - - - - - - - - - - - DctQ CMS1_k127_4884145_0 1187851.A33M_0093 1.294e-130 441.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQNK@28211|Alphaproteobacteria,3FDTN@34008|Rhodovulum 28211|Alphaproteobacteria G C4-dicarboxylate ABC transporter permease - - - - - - - - - - - - DctM CMS1_k127_4884145_1 1125973.JNLC01000010_gene1581 7.102e-53 200.0 COG2304@1|root,COG2304@2|Bacteria,1PH4N@1224|Proteobacteria,2TQTJ@28211|Alphaproteobacteria,3JSMW@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF1194) MA20_07505 - - - - - - - - - - - DUF1194 CMS1_k127_4884145_2 296591.Bpro_1408 5.074e-39 148.0 COG5588@1|root,COG5588@2|Bacteria 2|Bacteria S Protein of unknown function (DUF1326) - - - - - - - - - - - - DUF1326 CMS1_k127_4890028_8 107635.AZUO01000001_gene2542 1.412e-13 73.0 COG0007@1|root,COG1648@1|root,COG0007@2|Bacteria,COG1648@2|Bacteria,1MUI0@1224|Proteobacteria,2TRJC@28211|Alphaproteobacteria,36XUD@31993|Methylocystaceae 28211|Alphaproteobacteria H Putative NAD(P)-binding cobA - 1.3.1.76,2.1.1.107,4.99.1.4 ko:K02302,ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02864,R03194,R03947 RC00003,RC00871,RC01012,RC01034 ko00000,ko00001,ko00002,ko01000 - - - CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase CMS1_k127_4890028_5 936455.KI421499_gene7011 2.515e-49 180.0 COG4319@1|root,COG4319@2|Bacteria,1RD4M@1224|Proteobacteria,2UA09@28211|Alphaproteobacteria,3JY8P@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF3225) MA20_22680 - - - - - - - - - - - DUF3225 CMS1_k127_4890028_2 1245469.S58_06490 3.495e-206 650.0 COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2TR00@28211|Alphaproteobacteria,3JVVN@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Amidase MA20_22670 - 3.5.1.54 ko:K01457 ko00220,ko00791,ko01100,ko01120,map00220,map00791,map01100,map01120 - R00005 RC02756 ko00000,ko00001,ko01000 - - - Amidase CMS1_k127_4890028_7 1187851.A33M_3423 4.028e-23 104.0 2E9ZT@1|root,33457@2|Bacteria,1N7P1@1224|Proteobacteria,2UF38@28211|Alphaproteobacteria 28211|Alphaproteobacteria S PFAM BA14K family protein - - - - - - - - - - - - BA14K CMS1_k127_4890028_1 316056.RPC_1727 4.527e-286 902.0 COG4258@1|root,COG4258@2|Bacteria,1QW57@1224|Proteobacteria,2TSFU@28211|Alphaproteobacteria,3JQM0@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S MMPL family MA20_16030 - - ko:K07003 - - - - ko00000 - - - MMPL CMS1_k127_4890028_3 1380394.JADL01000001_gene2242 6.878e-93 315.0 COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria,2TQMD@28211|Alphaproteobacteria,2JPKA@204441|Rhodospirillales 204441|Rhodospirillales GM NmrA-like family - - 1.6.5.3,1.6.99.3 ko:K00329,ko:K00356 ko00190,map00190 - R11945 RC00061 ko00000,ko00001,ko01000 - - - 3Beta_HSD,Epimerase,NAD_binding_10,RmlD_sub_bind CMS1_k127_4890028_4 1120983.KB894574_gene929 7.52e-64 224.0 COG0251@1|root,COG0251@2|Bacteria,1Q7E6@1224|Proteobacteria,2UTJ8@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Endoribonuclease L-PSP - - - - - - - - - - - - Ribonuc_L-PSP CMS1_k127_4890028_0 1123229.AUBC01000009_gene321 0.0 1388.0 COG0587@1|root,COG0587@2|Bacteria,1MUE4@1224|Proteobacteria,2TRUB@28211|Alphaproteobacteria,3JUU5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase dnaE2 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 ko:K02337,ko:K14162 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon CMS1_k127_4890028_6 663610.JQKO01000008_gene141 2.972e-35 136.0 COG0389@1|root,COG0389@2|Bacteria,1MU5X@1224|Proteobacteria,2TQVR@28211|Alphaproteobacteria,3NAHY@45404|Beijerinckiaceae 28211|Alphaproteobacteria L Nucleotidyltransferase DNA polymerase involved in DNA repair MA20_15945 - - ko:K14161 - - - - ko00000,ko03400 - - - IMS,IMS_C CMS1_k127_4897776_0 1232683.ADIMK_0681 6.819e-107 349.0 COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,1RN6J@1236|Gammaproteobacteria,4641I@72275|Alteromonadaceae 1236|Gammaproteobacteria E Belongs to the cysteine synthase cystathionine beta- synthase family cysK - 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 - - - Glutaredoxin,PALP CMS1_k127_4897776_3 1177928.TH2_11729 7.522e-31 133.0 2F9ZR@1|root,3428V@2|Bacteria,1NY5S@1224|Proteobacteria,2USXM@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_4897776_1 1408164.MOLA814_00044 3.318e-90 311.0 COG2271@1|root,COG2271@2|Bacteria,1QVY6@1224|Proteobacteria,2WGUI@28216|Betaproteobacteria 28216|Betaproteobacteria G Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 CMS1_k127_4897776_2 266779.Meso_2438 2.877e-59 209.0 COG1910@1|root,COG1910@2|Bacteria,1MVS4@1224|Proteobacteria,2TU96@28211|Alphaproteobacteria,43NYI@69277|Phyllobacteriaceae 28211|Alphaproteobacteria L Helix-turn-helix domain - - - - - - - - - - - - HTH_17,PBP_like CMS1_k127_4910071_3 883078.HMPREF9695_02892 5.489e-25 105.0 COG1024@1|root,COG1024@2|Bacteria,1MXBB@1224|Proteobacteria,2TU4V@28211|Alphaproteobacteria,3JRS0@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Belongs to the enoyl-CoA hydratase isomerase family - - 4.1.1.41,4.2.1.17 ko:K01692,ko:K11264 ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212 M00032,M00087 R00923,R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093 RC00097,RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 CMS1_k127_4910071_1 1298867.AUES01000055_gene4814 4e-168 534.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQMJ@28211|Alphaproteobacteria,3JVXD@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E TOBE domain - - 3.6.3.30 ko:K02010 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10 - - ABC_tran,TOBE_2 CMS1_k127_4910071_2 1038859.AXAU01000003_gene5874 1.265e-150 486.0 COG1840@1|root,COG1840@2|Bacteria,1MXZ8@1224|Proteobacteria,2TRY8@28211|Alphaproteobacteria 28211|Alphaproteobacteria P ABC-type Fe3 transport system, periplasmic component - - - - - - - - - - - - SBP_bac_6 CMS1_k127_4910071_0 1038859.AXAU01000043_gene1228 2.919e-240 755.0 COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,2TVQS@28211|Alphaproteobacteria,3JV51@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K02011 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - BPD_transp_1 CMS1_k127_4912513_0 883080.HMPREF9697_02588 1.053e-190 600.0 COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,2TRQN@28211|Alphaproteobacteria,3JTAN@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K Participates in both transcription termination and antitermination nusA - - ko:K02600 - - - - ko00000,ko03009,ko03021 - - - HHH_5,KH_5,NusA_N,S1 CMS1_k127_4912513_2 1380355.JNIJ01000020_gene3830 4.041e-59 213.0 COG2740@1|root,COG2740@2|Bacteria,1RHPR@1224|Proteobacteria,2U9RY@28211|Alphaproteobacteria,3JUXE@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K Protein of unknown function (DUF448) MA20_23920 - - ko:K07742 - - - - ko00000 - - - DUF448,Ribosomal_L7Ae CMS1_k127_4912513_1 1429916.X566_10155 6.113e-127 417.0 COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,2TQMY@28211|Alphaproteobacteria,3JRUZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB - - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N,IF2_assoc CMS1_k127_4934181_2 264198.Reut_C6311 1.518e-23 102.0 COG0715@1|root,COG0715@2|Bacteria,1NS24@1224|Proteobacteria 1224|Proteobacteria P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - - - - - - - - - - NMT1_2 CMS1_k127_4934181_0 1038858.AXBA01000011_gene1454 2.043e-284 881.0 COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,2TTSQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria H Belongs to the UbiD family - - 4.1.1.98 ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04985,R04986 RC00391 ko00000,ko00001,ko00002,ko01000 - - - UbiD CMS1_k127_4934181_1 998674.ATTE01000001_gene3827 1.869e-176 573.0 COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,1RMH7@1236|Gammaproteobacteria 1236|Gammaproteobacteria S TRAP transporter, 4TM 12TM fusion protein - - - - - - - - - - - - DctM CMS1_k127_4947857_1 504832.OCAR_6216 1.673e-73 249.0 COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,2TQPM@28211|Alphaproteobacteria,3JU26@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - - GATase_6,SIS CMS1_k127_4947857_0 883078.HMPREF9695_01902 9.466e-88 298.0 COG2928@1|root,COG2928@2|Bacteria,1MWT5@1224|Proteobacteria,2TZPK@28211|Alphaproteobacteria,3JSAM@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF502) MA20_12960 - - - - - - - - - - - DUF502 CMS1_k127_4947857_3 1187851.A33M_1059 3.92e-43 160.0 COG3152@1|root,COG3152@2|Bacteria,1QECY@1224|Proteobacteria,2VB92@28211|Alphaproteobacteria,3FEK5@34008|Rhodovulum 28211|Alphaproteobacteria S Protein of unknown function (DUF805) - - - - - - - - - - - - DUF805 CMS1_k127_4947857_2 1187851.A33M_2886 4.606e-53 188.0 COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,2TR86@28211|Alphaproteobacteria,3FCSC@34008|Rhodovulum 28211|Alphaproteobacteria L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge CMS1_k127_4951749_0 318996.AXAZ01000009_gene4364 0.0 1291.0 COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2TS2I@28211|Alphaproteobacteria,3JSVM@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen nrdJ - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - Ribonuc_red_2_N,Ribonuc_red_lgC CMS1_k127_4951749_4 1380355.JNIJ01000045_gene5502 5.773e-77 259.0 COG3761@1|root,COG3761@2|Bacteria,1RHS3@1224|Proteobacteria,2U95G@28211|Alphaproteobacteria,3JYGF@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C NADH ubiquinone oxidoreductase subunit NDUFA12 MA20_29090 - 1.6.99.3 ko:K00356 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - NDUFA12 CMS1_k127_4951749_5 1429916.X566_19525 1.657e-59 217.0 COG4765@1|root,COG4765@2|Bacteria,1RHI7@1224|Proteobacteria,2UBR9@28211|Alphaproteobacteria,3JR7X@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Uncharacterized protein conserved in bacteria (DUF2155) - - - - - - - - - - - - DUF2155 CMS1_k127_4951749_2 1187851.A33M_1363 2.007e-104 343.0 COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,2U59K@28211|Alphaproteobacteria,3FD29@34008|Rhodovulum 28211|Alphaproteobacteria O Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine aat GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0044424,GO:0044464,GO:0140096 2.3.2.6 ko:K00684 - - R03813,R11443,R11444 RC00055,RC00064 ko00000,ko01000 - - - Leu_Phe_trans CMS1_k127_4951749_7 1187851.A33M_0495 2.05e-18 91.0 COG0784@1|root,COG0784@2|Bacteria,1RKBP@1224|Proteobacteria,2UZMH@28211|Alphaproteobacteria,3FEGG@34008|Rhodovulum 2|Bacteria T cheY-homologous receiver domain - - - - - - - - - - - - HATPase_c,HisKA,PAS_3,PAS_9,Response_reg CMS1_k127_4951749_3 1161401.ASJA01000001_gene413 3.801e-85 291.0 COG0657@1|root,COG0657@2|Bacteria,1RGPG@1224|Proteobacteria,2UA65@28211|Alphaproteobacteria,43XAJ@69657|Hyphomonadaceae 28211|Alphaproteobacteria I alpha/beta hydrolase fold - - - - - - - - - - - - Abhydrolase_3,Abhydrolase_6 CMS1_k127_4951749_1 1429916.X566_19560 1.931e-251 780.0 COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,2U25Z@28211|Alphaproteobacteria,3JTBZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Biotin carboxylase accC GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 CMS1_k127_4951749_6 1040989.AWZU01000019_gene1947 8.674e-40 150.0 COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,2U93Y@28211|Alphaproteobacteria,3JY4E@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA accB GO:0003674,GO:0003824,GO:0003989,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009305,GO:0009987,GO:0016049,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576 - ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742 RC00040,RC00367 ko00000,ko00001,ko00002 - - - Biotin_lipoyl CMS1_k127_4968009_7 1187851.A33M_2283 7.47e-102 338.0 COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,2TRWB@28211|Alphaproteobacteria,3FCRA@34008|Rhodovulum 28211|Alphaproteobacteria EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia trpE - 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Anth_synt_I_N,Chorismate_bind CMS1_k127_4968009_2 316056.RPC_2468 4.584e-194 630.0 COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,2TRYU@28211|Alphaproteobacteria,3JQRF@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O Peptidylprolyl isomerase ppiD - 5.2.1.8 ko:K01802,ko:K03770 - - - - ko00000,ko01000,ko03110 - - - Rotamase_2,SurA_N_3 CMS1_k127_4968009_6 1187851.A33M_2281 1.56e-107 353.0 COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,2TS6I@28211|Alphaproteobacteria,3FCZ1@34008|Rhodovulum 28211|Alphaproteobacteria J Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - - TIM CMS1_k127_4968009_10 1125973.JNLC01000017_gene3573 1.443e-38 149.0 COG1314@1|root,COG1314@2|Bacteria,1N8MF@1224|Proteobacteria,2UCIP@28211|Alphaproteobacteria,3JYS8@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria U Preprotein translocase SecG subunit secG - - ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecG CMS1_k127_4968009_0 1040989.AWZU01000003_gene6824 0.0 1001.0 COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,2TS4Y@28211|Alphaproteobacteria,3JTRN@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates pyrG - 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 - - - CTP_synth_N,GATase CMS1_k127_4968009_8 1380355.JNIJ01000047_gene232 4.604e-77 270.0 COG0346@1|root,COG0346@2|Bacteria,1MZT5@1224|Proteobacteria,2U4GS@28211|Alphaproteobacteria,3JUDJ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Glyoxalase-like domain - - - - - - - - - - - - Glyoxalase_3 CMS1_k127_4968009_4 316056.RPC_2477 2.962e-143 458.0 COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,2TRJX@28211|Alphaproteobacteria,3JUB6@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase kdsA - 2.5.1.55 ko:K01627 ko00540,ko01100,map00540,map01100 M00063 R03254 RC00435 ko00000,ko00001,ko00002,ko01000,ko01005 - - - DAHP_synth_1 CMS1_k127_4968009_5 1187851.A33M_2276 3.596e-109 365.0 COG0477@1|root,COG2814@2|Bacteria,1R7QS@1224|Proteobacteria,2TUXM@28211|Alphaproteobacteria 28211|Alphaproteobacteria EGP Major Facilitator - - - - - - - - - - - - MFS_1 CMS1_k127_4968009_9 402881.Plav_3151 1.821e-73 265.0 COG0780@1|root,COG0780@2|Bacteria,1MW0M@1224|Proteobacteria,2U57X@28211|Alphaproteobacteria,1JQ5N@119043|Rhodobiaceae 28211|Alphaproteobacteria F Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) queF - 1.7.1.13 ko:K09457 ko00790,ko01100,map00790,map01100 - R07605 RC01875 ko00000,ko00001,ko01000,ko03016 - - - QueF CMS1_k127_4968009_1 258594.RPA2874 6.021e-223 697.0 COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,2TR04@28211|Alphaproteobacteria,3JQMG@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria F Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis eno - 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N CMS1_k127_4968009_11 113395.AXAI01000015_gene448 9.591e-29 118.0 COG2919@1|root,COG2919@2|Bacteria,1N8WI@1224|Proteobacteria,2UGEU@28211|Alphaproteobacteria,3JZFR@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria D Septum formation initiator MA20_41765 - - - - - - - - - - - DivIC CMS1_k127_4968009_3 666684.AfiDRAFT_3278 9.1e-172 547.0 COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,2TRSS@28211|Alphaproteobacteria,3JS9V@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) pdhA - 1.2.4.1 ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh CMS1_k127_4979297_1 1298867.AUES01000004_gene523 1.869e-35 135.0 COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,2TRHX@28211|Alphaproteobacteria,3JQRE@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatB GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 ko:K02434 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - GatB_N,GatB_Yqey CMS1_k127_4979297_4 652103.Rpdx1_4566 1.524e-16 85.0 COG3631@1|root,COG3631@2|Bacteria,1RBYP@1224|Proteobacteria,2U5DA@28211|Alphaproteobacteria,3JYF6@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S SnoaL-like domain MA20_05325 - - - - - - - - - - - SnoaL_2 CMS1_k127_4979297_3 1040989.AWZU01000001_gene5754 9.953e-24 108.0 COG3631@1|root,COG3631@2|Bacteria,1RBYP@1224|Proteobacteria,2U5DA@28211|Alphaproteobacteria,3JYF6@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S SnoaL-like domain MA20_05325 - - - - - - - - - - - SnoaL_2 CMS1_k127_4979297_2 1040989.AWZU01000053_gene2351 2.935e-32 128.0 2C4KB@1|root,32YM4@2|Bacteria,1N74A@1224|Proteobacteria,2UHJ4@28211|Alphaproteobacteria,3JZRB@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_4979297_0 316055.RPE_3358 2.463e-239 744.0 COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2TRFY@28211|Alphaproteobacteria,3JU77@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) gatA - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase CMS1_k127_4997047_6 1038859.AXAU01000010_gene1878 1.358e-69 237.0 COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,2TRUY@28211|Alphaproteobacteria,3JQPQ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O prohibitin homologues - - - - - - - - - - - - Band_7 CMS1_k127_4997047_2 395964.KE386496_gene2234 3.611e-134 432.0 COG0115@1|root,COG0115@2|Bacteria,1MX5D@1224|Proteobacteria,2TRVR@28211|Alphaproteobacteria,3NC55@45404|Beijerinckiaceae 28211|Alphaproteobacteria EH Amino-transferase class IV MA20_39585 - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_4 CMS1_k127_4997047_5 1187851.A33M_0023 5.759e-87 292.0 COG1011@1|root,COG1011@2|Bacteria,1MVWN@1224|Proteobacteria,2TS5K@28211|Alphaproteobacteria,3FD6W@34008|Rhodovulum 28211|Alphaproteobacteria S Haloacid dehalogenase-like hydrolase dehII - 3.8.1.2 ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05287 RC00697 ko00000,ko00001,ko01000 - - - HAD_2,Hydrolase CMS1_k127_4997047_1 1429916.X566_02705 3.398e-154 491.0 COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,2TR2Q@28211|Alphaproteobacteria,3JU27@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria V ABC transporter hndI GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran CMS1_k127_4997047_3 1429916.X566_02700 7.394e-128 413.0 COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,2TQSY@28211|Alphaproteobacteria,3JRRG@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria V transport, permease protein yadH GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane CMS1_k127_4997047_0 1211115.ALIQ01000056_gene2731 1.126e-203 644.0 COG0624@1|root,COG0624@2|Bacteria,1MW20@1224|Proteobacteria,2TQY4@28211|Alphaproteobacteria,3NAN8@45404|Beijerinckiaceae 28211|Alphaproteobacteria E Peptidase dimerisation domain MA20_15735 - - ko:K01436 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 CMS1_k127_4997047_9 224914.BMEI1371 1.159e-31 131.0 2AUTH@1|root,31KGJ@2|Bacteria,1RH09@1224|Proteobacteria,2UAJV@28211|Alphaproteobacteria,1J2YQ@118882|Brucellaceae 28211|Alphaproteobacteria - - MA20_15750 - - - - - - - - - - - DUF2780 CMS1_k127_4997047_8 1187851.A33M_0031 1.146e-41 164.0 COG3743@1|root,COG3743@2|Bacteria,1RA3K@1224|Proteobacteria,2U7GQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Domain of unknown function (DUF4332) MA20_15755 - - - - - - - - - - - DUF4332 CMS1_k127_4997047_4 504832.OCAR_6642 1.637e-116 381.0 COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,2TTMG@28211|Alphaproteobacteria,3JRVE@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives folP - 2.5.1.15,2.7.6.3 ko:K00796,ko:K13941,ko:K18824 ko00790,ko01100,map00790,map01100 M00126,M00840,M00841 R03066,R03067,R03503 RC00002,RC00017,RC00121,RC00842 ko00000,ko00001,ko00002,ko01000,ko01504 - - - Pterin_bind CMS1_k127_4997047_7 196490.AUEZ01000075_gene7644 5.867e-42 158.0 COG1539@1|root,COG1539@2|Bacteria,1RHII@1224|Proteobacteria,2UGT3@28211|Alphaproteobacteria,3JZ50@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin folB - 1.13.11.81,4.1.2.25,5.1.99.8 ko:K01633 ko00790,ko01100,map00790,map01100 M00126,M00840 R03504,R11037,R11073 RC00721,RC00943,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 - - - FolB CMS1_k127_4997479_0 318996.AXAZ01000017_gene823 4.489e-126 405.0 COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,2TRP3@28211|Alphaproteobacteria,3JQSF@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives lipA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 ko:K03644 ko00785,ko01100,map00785,map01100 - R07767,R07768 RC01978 ko00000,ko00001,ko01000 - - - LIAS_N,Radical_SAM CMS1_k127_4997479_2 883078.HMPREF9695_03087 1.743e-15 79.0 COG2261@1|root,COG2261@2|Bacteria,1N72Y@1224|Proteobacteria,2UFM5@28211|Alphaproteobacteria,3K0CJ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Transglycosylase associated protein MA20_01300 - - - - - - - - - - - Transgly_assoc CMS1_k127_4997479_1 392499.Swit_4248 1.129e-64 228.0 COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,2TQNW@28211|Alphaproteobacteria 28211|Alphaproteobacteria C COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases mdlB - 1.1.2.3,1.1.99.31 ko:K00101,ko:K15054 ko00620,ko00627,ko01100,ko01120,map00620,map00627,map01100,map01120 - R00196,R04160,R07664 RC00044,RC00240 ko00000,ko00001,ko01000 - - - FMN_dh CMS1_k127_4997527_1 666509.RCA23_c23240 5.185e-54 190.0 COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,2TQQG@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) hpaG - 5.3.3.10 ko:K01826 ko00350,ko01120,ko01220,map00350,map01120,map01220 M00533 R04379,R04482 RC01141,RC01162 ko00000,ko00001,ko00002,ko01000 - - - FAA_hydrolase CMS1_k127_4997527_0 1187851.A33M_0952 3.12e-207 652.0 COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,2TSCJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) - - - - - - - - - - - - HMGL-like CMS1_k127_5002237_1 1510531.JQJJ01000012_gene1648 2.371e-246 764.0 COG0604@1|root,COG0604@2|Bacteria,1MXIK@1224|Proteobacteria,2TQPR@28211|Alphaproteobacteria,3JWZS@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Alcohol dehydrogenase GroES-like domain ccrA - 1.1.1.1,1.3.1.85 ko:K00001,ko:K14446 ko00010,ko00071,ko00350,ko00625,ko00626,ko00630,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00010,map00071,map00350,map00625,map00626,map00630,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220 M00373 R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310,R09291 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273,RC02481 ko00000,ko00001,ko00002,ko01000 - - - ADH_N,ADH_zinc_N CMS1_k127_5002237_2 1168059.KB899087_gene3879 9.986e-103 342.0 COG1295@1|root,COG1295@2|Bacteria,1MXQA@1224|Proteobacteria,2TTN5@28211|Alphaproteobacteria,3EZ17@335928|Xanthobacteraceae 28211|Alphaproteobacteria S Virulence factor BrkB MA20_20550 - - ko:K07058 - - - - ko00000 - - - Virul_fac_BrkB CMS1_k127_5002237_3 1211115.ALIQ01000204_gene4778 7.324e-95 336.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2TQR7@28211|Alphaproteobacteria 28211|Alphaproteobacteria T methyl-accepting chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal CMS1_k127_5002237_0 1187851.A33M_3766 4.798e-267 831.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TR78@28211|Alphaproteobacteria,3FCMW@34008|Rhodovulum 28211|Alphaproteobacteria I Acyl-CoA dehydrogenase, C-terminal domain mcd - 1.3.8.12 ko:K14448 ko00630,ko01120,ko01200,map00630,map01120,map01200 M00373 R09293 RC02483 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N CMS1_k127_5002237_4 1304878.AUGD01000020_gene4307 1.028e-51 187.0 COG5622@1|root,COG5622@2|Bacteria,1RIEJ@1224|Proteobacteria,2U7UE@28211|Alphaproteobacteria,3JVUA@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria N Protein required for attachment to host cells MA20_35675 - - - - - - - - - - - Host_attach CMS1_k127_5002237_5 196490.AUEZ01000039_gene7067 6.829e-48 175.0 COG0834@1|root,COG0834@2|Bacteria,1MXIA@1224|Proteobacteria,2VETI@28211|Alphaproteobacteria,3JS6K@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria ET Bacterial periplasmic substrate-binding proteins MA20_22110 - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 CMS1_k127_5005341_2 670292.JH26_24865 1.808e-22 98.0 COG3514@1|root,COG3514@2|Bacteria,1MZPR@1224|Proteobacteria,2UCYI@28211|Alphaproteobacteria,1JVX4@119045|Methylobacteriaceae 28211|Alphaproteobacteria S BrnA antitoxin of type II toxin-antitoxin system - - - - - - - - - - - - BrnA_antitoxin CMS1_k127_5005341_0 420324.KI911996_gene7818 2.206e-36 149.0 COG1452@1|root,COG1452@2|Bacteria 2|Bacteria M lipopolysaccharide transport - - - ko:K09774 - - - - ko00000,ko02000 1.B.42.1 - - LptC CMS1_k127_5005341_1 83219.PM02_17835 1.067e-29 119.0 COG3000@1|root,COG3000@2|Bacteria,1MW5G@1224|Proteobacteria,2TU63@28211|Alphaproteobacteria,3ZXCP@60136|Sulfitobacter 28211|Alphaproteobacteria I Fatty acid hydroxylase superfamily - - - - - - - - - - - - FA_hydroxylase CMS1_k127_5009359_31 1144310.PMI07_005439 5.759e-15 76.0 COG0600@1|root,COG0600@2|Bacteria,1PF1W@1224|Proteobacteria,2UQ2K@28211|Alphaproteobacteria,4BJDU@82115|Rhizobiaceae 28211|Alphaproteobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K02050 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - BPD_transp_1 CMS1_k127_5009359_25 670307.HYPDE_36178 6.56e-32 132.0 COG3668@1|root,32ZH9@2|Bacteria,1N7YH@1224|Proteobacteria,2UC0X@28211|Alphaproteobacteria,3N8Z1@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria S Plasmid stabilization - - - - - - - - - - - - - CMS1_k127_5009359_23 1187851.A33M_3125 9.177e-45 169.0 COG1376@1|root,COG1376@2|Bacteria,1MUAB@1224|Proteobacteria,2TTXM@28211|Alphaproteobacteria,3FEDG@34008|Rhodovulum 28211|Alphaproteobacteria S L,D-transpeptidase catalytic domain - - - - - - - - - - - - YkuD CMS1_k127_5009359_16 1197906.CAJQ02000026_gene3734 5.869e-94 322.0 COG3770@1|root,COG3770@2|Bacteria,1MU9I@1224|Proteobacteria,2TR3K@28211|Alphaproteobacteria,3JRJZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Penicillin-insensitive murein endopeptidase mepA - - ko:K07261 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M74 CMS1_k127_5009359_0 864069.MicloDRAFT_00018460 0.0 1289.0 COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,2TSZ9@28211|Alphaproteobacteria,1JRSQ@119045|Methylobacteriaceae 28211|Alphaproteobacteria C Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) MA20_17010 - 1.2.4.1 ko:K00163 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transketolase_N CMS1_k127_5009359_1 258594.RPA3211 4.374e-306 982.0 COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1MWRF@1224|Proteobacteria,2TS2A@28211|Alphaproteobacteria,3JS1R@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S CHAT domain - - - - - - - - - - - - CHAT,TPR_10,TPR_12 CMS1_k127_5009359_2 1168059.KB899087_gene592 1.301e-258 806.0 COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,2TQKQ@28211|Alphaproteobacteria,3EYT4@335928|Xanthobacteraceae 28211|Alphaproteobacteria E GMC oxidoreductase MA20_15975 - 1.1.99.1 ko:K00108 ko00260,ko01100,map00260,map01100 M00555 R01025 RC00087 ko00000,ko00001,ko00002,ko01000 - - - GMC_oxred_C,GMC_oxred_N CMS1_k127_5009359_17 1298867.AUES01000068_gene3166 7.831e-85 291.0 COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,2U5B1@28211|Alphaproteobacteria,3JU6M@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein modA - - ko:K02020 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko02000 3.A.1.8 - - SBP_bac_11 CMS1_k127_5009359_15 113395.AXAI01000005_gene3948 9.752e-100 336.0 COG4149@1|root,COG4149@2|Bacteria,1MUXR@1224|Proteobacteria,2TSYJ@28211|Alphaproteobacteria,3JQTG@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P Binding-protein-dependent transport system inner membrane component modB - - ko:K02018 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko02000 3.A.1.8 - - BPD_transp_1 CMS1_k127_5009359_18 709797.CSIRO_0594 1.247e-84 286.0 COG4148@1|root,COG4148@2|Bacteria,1MU8K@1224|Proteobacteria,2TR1Z@28211|Alphaproteobacteria,3JUD5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system modC - 3.6.3.29 ko:K02017 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.8 - - ABC_tran,TOBE CMS1_k127_5009359_14 258594.RPA2805 4.241e-103 338.0 2BZ0R@1|root,2Z7U0@2|Bacteria,1MX37@1224|Proteobacteria,2TSBD@28211|Alphaproteobacteria,3JT2X@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Nitrile hydratase, alpha chain nthA - 4.2.1.84 ko:K01721 ko00364,ko00380,ko00627,ko00643,ko01120,map00364,map00380,map00627,map00643,map01120 - R02828,R04020,R05379,R05596,R07780,R07854 RC00483,RC00792,RC01345,RC01432 ko00000,ko00001,ko01000 - - - NHase_alpha CMS1_k127_5009359_20 1380355.JNIJ01000013_gene452 1.531e-77 266.0 28I45@1|root,2Z87Q@2|Bacteria,1R432@1224|Proteobacteria,2U3PK@28211|Alphaproteobacteria,3JS7H@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E NHase catalyzes the hydration of various nitrile compounds to the corresponding amides nthB - 4.2.1.84 ko:K20807 ko00364,ko00380,ko00627,ko00643,ko01120,map00364,map00380,map00627,map00643,map01120 - R04020,R05379,R05596,R07780,R07854 RC00483,RC01345,RC01432 ko00000,ko00001,ko01000 - - - NHase_beta CMS1_k127_5009359_5 1123257.AUFV01000019_gene2041 1.293e-178 586.0 COG0154@1|root,COG0154@2|Bacteria,1NS7J@1224|Proteobacteria,1SMJ8@1236|Gammaproteobacteria,1XA2W@135614|Xanthomonadales 135614|Xanthomonadales J Amidase - - - - - - - - - - - - Amidase CMS1_k127_5009359_12 1317124.DW2_03649 5.035e-108 355.0 COG0614@1|root,COG0614@2|Bacteria,1PK1C@1224|Proteobacteria,2TRF4@28211|Alphaproteobacteria,2XKIN@285107|Thioclava 28211|Alphaproteobacteria P Periplasmic binding protein - - - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - Peripla_BP_2 CMS1_k127_5009359_26 1242864.D187_004429 1.245e-29 125.0 2CBKC@1|root,32RTJ@2|Bacteria,1N5I0@1224|Proteobacteria,431GW@68525|delta/epsilon subdivisions,2WX2N@28221|Deltaproteobacteria 28221|Deltaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_5009359_3 1187851.A33M_0113 2.626e-227 718.0 COG3263@1|root,COG3263@2|Bacteria,1MVKV@1224|Proteobacteria,2TSZJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria P COG3263 NhaP-type Na H and K H antiporters with a unique C-terminal domain cvrA - - ko:K11105 - - - - ko00000,ko02000 2.A.36.6 - - CorC_HlyC,Na_H_Exchanger CMS1_k127_5009359_8 1187851.A33M_0093 1.279e-129 428.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQNK@28211|Alphaproteobacteria,3FDTN@34008|Rhodovulum 28211|Alphaproteobacteria G C4-dicarboxylate ABC transporter permease - - - - - - - - - - - - DctM CMS1_k127_5009359_27 1187851.A33M_0092 3.176e-26 115.0 COG3090@1|root,COG3090@2|Bacteria,1QYHJ@1224|Proteobacteria,2UI8I@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Tripartite ATP-independent periplasmic transporters, DctQ component - - - - - - - - - - - - DctQ CMS1_k127_5009359_11 1187851.A33M_0090 4.555e-115 382.0 COG1638@1|root,COG1638@2|Bacteria,1PJG1@1224|Proteobacteria,2V8IQ@28211|Alphaproteobacteria,3FEKB@34008|Rhodovulum 28211|Alphaproteobacteria G Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP CMS1_k127_5009359_6 1411123.JQNH01000001_gene3180 2.29e-166 527.0 COG3246@1|root,COG3246@2|Bacteria,1MZTP@1224|Proteobacteria,2TQKN@28211|Alphaproteobacteria 28211|Alphaproteobacteria S PFAM Prokaryotic protein of - - - - - - - - - - - - BKACE CMS1_k127_5009359_19 1038859.AXAU01000001_gene3549 7.091e-82 282.0 COG0697@1|root,COG0697@2|Bacteria,1RI87@1224|Proteobacteria,2UAJW@28211|Alphaproteobacteria,3JW3Q@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria EG EamA-like transporter family MA20_28970 - - - - - - - - - - - EamA CMS1_k127_5009359_9 316056.RPC_0579 1.738e-125 417.0 COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,2TRKK@28211|Alphaproteobacteria,3JSMB@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Mechanosensitive ion channel MA20_40450 - - - - - - - - - - - MS_channel CMS1_k127_5009359_4 1187851.A33M_0543 1.731e-215 674.0 COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2TRPK@28211|Alphaproteobacteria,3FCRW@34008|Rhodovulum 28211|Alphaproteobacteria E Aminotransferase class I and II - - - - - - - - - - - - Aminotran_1_2 CMS1_k127_5009359_13 595537.Varpa_0136 3.027e-104 347.0 COG2513@1|root,COG2513@2|Bacteria,1R3SD@1224|Proteobacteria,2VK7I@28216|Betaproteobacteria,4ACD1@80864|Comamonadaceae 28216|Betaproteobacteria G Phosphoenolpyruvate phosphomutase - - - - - - - - - - - - PEP_mutase CMS1_k127_5009359_22 1211115.ALIQ01000140_gene1264 6.667e-72 255.0 COG1670@1|root,COG1670@2|Bacteria,1MXEE@1224|Proteobacteria,2U62V@28211|Alphaproteobacteria 28211|Alphaproteobacteria J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - - - - - - - - - - Acetyltransf_3 CMS1_k127_5009359_10 1380394.JADL01000009_gene3331 3.322e-123 407.0 COG0477@1|root,COG2814@2|Bacteria,1QTX0@1224|Proteobacteria,2TUM5@28211|Alphaproteobacteria,2JZ6U@204441|Rhodospirillales 204441|Rhodospirillales EGP Transmembrane secretion effector - - - - - - - - - - - - MFS_3 CMS1_k127_5009359_7 1411123.JQNH01000001_gene140 2.097e-146 470.0 COG0451@1|root,COG0451@2|Bacteria,1MU1A@1224|Proteobacteria,2TU1A@28211|Alphaproteobacteria 28211|Alphaproteobacteria GM epimerase dehydratase MA20_27225 - 1.1.1.410 ko:K22025 - - - - ko00000,ko01000 - - - Epimerase CMS1_k127_5009359_29 449447.MAE_62950 4.803e-19 89.0 COG0628@1|root,COG0628@2|Bacteria,1G26W@1117|Cyanobacteria 1117|Cyanobacteria S AI-2E family transporter - - - - - - - - - - - - AI-2E_transport CMS1_k127_5009359_24 398525.KB900701_gene4139 3.995e-39 162.0 COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,2TVGG@28211|Alphaproteobacteria,3JSIB@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S AI-2E family transporter - - - - - - - - - - - - AI-2E_transport CMS1_k127_5009359_28 936455.KI421499_gene2590 7.315e-22 99.0 COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,2TVGG@28211|Alphaproteobacteria,3JSIB@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S AI-2E family transporter MA20_41055 - - - - - - - - - - - AI-2E_transport CMS1_k127_5009359_21 709797.CSIRO_0599 9.827e-77 263.0 COG1489@1|root,COG1489@2|Bacteria,1MUC3@1224|Proteobacteria,2U10V@28211|Alphaproteobacteria,3K3H5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Sugar fermentation stimulation protein sfsA - - ko:K06206 - - - - ko00000 - - - SfsA CMS1_k127_5044741_4 114615.BRADO6712 4.285e-24 101.0 COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,2TRSR@28211|Alphaproteobacteria,3JUF4@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Putative modulator of DNA gyrase tldD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K03568 - - - - ko00000,ko01002 - - - PmbA_TldD CMS1_k127_5044741_0 420324.KI912069_gene6373 9.473e-170 550.0 COG2374@1|root,COG2374@2|Bacteria,1R5QF@1224|Proteobacteria,2U002@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Endonuclease Exonuclease phosphatase - - - - - - - - - - - - Exo_endo_phos CMS1_k127_5044741_5 1187851.A33M_3424 9.095e-14 77.0 COG5457@1|root,COG5457@2|Bacteria,1NHP7@1224|Proteobacteria,2UJR8@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Domain of unknown function (DUF1127) - - - - - - - - - - - - DUF1127 CMS1_k127_5044741_1 1187851.A33M_3425 3.55e-143 458.0 COG0583@1|root,COG0583@2|Bacteria,1PR6U@1224|Proteobacteria,2TUC6@28211|Alphaproteobacteria,3FD7M@34008|Rhodovulum 28211|Alphaproteobacteria K LysR substrate binding domain dgdR - - - - - - - - - - - HTH_1,LysR_substrate CMS1_k127_5044741_3 1187851.A33M_4424 5.181e-60 213.0 COG2606@1|root,COG2606@2|Bacteria,1RGX5@1224|Proteobacteria,2U5DV@28211|Alphaproteobacteria,3FEAX@34008|Rhodovulum 28211|Alphaproteobacteria J Aminoacyl-tRNA editing domain ybaK GO:0002161,GO:0003674,GO:0003824,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0043906,GO:0044237,GO:0044238,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - ko:K03976 - - - - ko00000,ko01000,ko03016 - - - tRNA_edit CMS1_k127_5044741_2 258594.RPA0822 1.804e-121 393.0 COG3572@1|root,COG3572@2|Bacteria,1MU47@1224|Proteobacteria,2TRPT@28211|Alphaproteobacteria,3JR2Q@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H glutamate--cysteine ligase gshA - 6.3.2.2 ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - GCS2 CMS1_k127_5050631_0 1123368.AUIS01000003_gene1577 1.647e-125 409.0 COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,1RNVF@1236|Gammaproteobacteria,2NC14@225057|Acidithiobacillales 225057|Acidithiobacillales E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate argJ - 2.3.1.1,2.3.1.35 ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259,R02282 RC00004,RC00064 ko00000,ko00001,ko00002,ko01000 - - - ArgJ CMS1_k127_5050631_1 1049564.TevJSym_ai00320 1.553e-49 184.0 COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,1S3NR@1236|Gammaproteobacteria,1J5WU@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A coaE GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - iECP_1309.ECP_0104 CoaE CMS1_k127_5051188_1 1187851.A33M_0544 8.044e-83 280.0 COG0524@1|root,COG0524@2|Bacteria,1MVG2@1224|Proteobacteria,2TSDV@28211|Alphaproteobacteria,3FE8E@34008|Rhodovulum 28211|Alphaproteobacteria G pfkB family carbohydrate kinase kdgK - 2.7.1.45 ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 M00061,M00308,M00631 R01541 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - PfkB CMS1_k127_5051188_0 1040989.AWZU01000008_gene3768 5.557e-109 358.0 COG1108@1|root,COG1108@2|Bacteria,1PWU3@1224|Proteobacteria,2TVJQ@28211|Alphaproteobacteria,3K394@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P ABC 3 transport family - - - ko:K02075 - M00244 - - ko00000,ko00002,ko02000 3.A.1.15 - - ABC-3 CMS1_k127_5051188_2 1040989.AWZU01000008_gene3767 1.038e-41 155.0 COG1121@1|root,COG1121@2|Bacteria,1MUDW@1224|Proteobacteria,2TQUI@28211|Alphaproteobacteria,3K375@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P AAA domain, putative AbiEii toxin, Type IV TA system - - - ko:K02074,ko:K09817 ko02010,map02010 M00242,M00244 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 - - ABC_tran CMS1_k127_5080292_2 261292.Nit79A3_0736 1.461e-42 161.0 COG4324@1|root,COG4324@2|Bacteria,1N0FE@1224|Proteobacteria,2VH73@28216|Betaproteobacteria,371PB@32003|Nitrosomonadales 28216|Betaproteobacteria S Putative aminopeptidase - - - - - - - - - - - - Aminopep CMS1_k127_5080292_0 713586.KB900536_gene2508 8.145e-111 366.0 COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria,1RNS7@1236|Gammaproteobacteria,1WXE7@135613|Chromatiales 135613|Chromatiales GM NAD-dependent epimerase dehydratase - - 1.6.5.3,1.6.99.3 ko:K00329,ko:K00356 ko00190,map00190 - R11945 RC00061 ko00000,ko00001,ko01000 - - - Epimerase,NAD_binding_10 CMS1_k127_5080292_1 396588.Tgr7_1499 1.586e-47 179.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WVV9@135613|Chromatiales 135613|Chromatiales T Diguanylate cyclase - - - - - - - - - - - - EAL,GAF_2,GGDEF CMS1_k127_5080965_1 316057.RPD_4199 0.0 1146.0 COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria,3JURY@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - - - - - - - - - - ACR_tran CMS1_k127_5080965_3 414684.RC1_2441 0.0 1040.0 COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2TRZD@28211|Alphaproteobacteria,2JQS7@204441|Rhodospirillales 204441|Rhodospirillales P COG0474 Cation transport ATPase - - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 CMS1_k127_5080965_6 1304877.KI519399_gene6160 2.129e-147 473.0 COG0530@1|root,COG0530@2|Bacteria,1PW8G@1224|Proteobacteria,2U168@28211|Alphaproteobacteria 28211|Alphaproteobacteria P COG0530 Ca2 Na antiporter - - - ko:K07301 - - - - ko00000,ko02000 2.A.19.5 - - Na_Ca_ex CMS1_k127_5080965_2 991905.SL003B_2630 0.0 1068.0 COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2TRZD@28211|Alphaproteobacteria 28211|Alphaproteobacteria P TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC - - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 CMS1_k127_5080965_4 472759.Nhal_1697 3.542e-195 615.0 COG0438@1|root,COG0438@2|Bacteria,1MYTB@1224|Proteobacteria,1S04A@1236|Gammaproteobacteria 1224|Proteobacteria M glycosyl transferase group 1 - - 2.4.1.245 ko:K13057 ko00500,ko01100,map00500,map01100 - R08946,R10525,R11306 RC00005,RC00049,RC02748 ko00000,ko00001,ko01000 - GT4 - Glycos_transf_1 CMS1_k127_5080965_0 1336235.JAEG01000012_gene4143 0.0 1263.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,2TR38@28211|Alphaproteobacteria,4B9IV@82115|Rhizobiaceae 28211|Alphaproteobacteria G Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate - - 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PEP-utilizers_C,PPDK_N CMS1_k127_5080965_9 1125863.JAFN01000001_gene2498 1.289e-76 268.0 COG1085@1|root,COG1085@2|Bacteria,1MU3E@1224|Proteobacteria,42MP4@68525|delta/epsilon subdivisions,2WKT8@28221|Deltaproteobacteria 28221|Deltaproteobacteria C TIGRFAM galactose-1-phosphate uridylyltransferase galT - 2.7.7.12 ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 M00362,M00554,M00632 R00955 RC00002 ko00000,ko00001,ko00002,ko01000 - - - DUF4921,GalP_UDP_tr_C,GalP_UDP_transf CMS1_k127_5080965_7 118168.MC7420_848 1.041e-121 398.0 COG1052@1|root,COG1052@2|Bacteria,1G028@1117|Cyanobacteria,1H7XD@1150|Oscillatoriales 1117|Cyanobacteria CH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - - - - - - - - - - 2-Hacid_dh,2-Hacid_dh_C CMS1_k127_5080965_8 1380394.JADL01000002_gene1196 2.979e-101 338.0 COG0837@1|root,COG0837@2|Bacteria,1MVFI@1224|Proteobacteria,2U0CA@28211|Alphaproteobacteria,2JS5Q@204441|Rhodospirillales 204441|Rhodospirillales G Belongs to the bacterial glucokinase family glk - 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Glucokinase CMS1_k127_5080965_11 1120956.JHZK01000026_gene791 5.467e-12 70.0 2EBP1@1|root,335P7@2|Bacteria,1NEQC@1224|Proteobacteria,2UF3H@28211|Alphaproteobacteria,1JQJJ@119043|Rhodobiaceae 28211|Alphaproteobacteria S Glycine zipper - - - - - - - - - - - - Gly-zipper_Omp,Gly-zipper_YMGG CMS1_k127_5080965_5 1089552.KI911559_gene598 1.114e-169 547.0 COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,2TR24@28211|Alphaproteobacteria,2JPV8@204441|Rhodospirillales 204441|Rhodospirillales C COG1042 Acyl-CoA synthetase (NDP forming) yfiQ - - ko:K09181 - - - - ko00000 - - - ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig CMS1_k127_5085022_1 288000.BBta_0273 4.796e-63 219.0 COG0518@1|root,COG0518@2|Bacteria,1MUDH@1224|Proteobacteria,2TU60@28211|Alphaproteobacteria,3JRGP@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria F Glutamine amidotransferase class-I guaA2 - 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase CMS1_k127_5085022_0 323098.Nwi_0477 7.261e-85 292.0 COG0300@1|root,COG0300@2|Bacteria,1RG9T@1224|Proteobacteria,2TW0V@28211|Alphaproteobacteria,3JS8Y@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Belongs to the short-chain dehydrogenases reductases (SDR) family MA20_25205 - - ko:K07124 - - - - ko00000 - - - adh_short CMS1_k127_5085022_2 196490.AUEZ01000023_gene7105 4.971e-44 165.0 COG4103@1|root,COG4103@2|Bacteria,1N6YZ@1224|Proteobacteria,2U93G@28211|Alphaproteobacteria,3JUGW@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Tellurite resistance protein TerB - - - - - - - - - - - - TerB CMS1_k127_511542_3 936455.KI421499_gene2722 9.874e-129 419.0 COG0006@1|root,COG0006@2|Bacteria,1MVJK@1224|Proteobacteria,2TVVP@28211|Alphaproteobacteria,3JSAA@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Creatinase/Prolidase N-terminal domain - - - - - - - - - - - - Creatinase_N,Peptidase_M24 CMS1_k127_511542_6 1082931.KKY_2539 2.206e-84 288.0 COG3384@1|root,COG3384@2|Bacteria,1MW77@1224|Proteobacteria,2TRP1@28211|Alphaproteobacteria,3N93B@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria S Catalytic LigB subunit of aromatic ring-opening dioxygenase - - 1.13.11.16,1.13.11.8 ko:K04101,ko:K05713 ko00360,ko00362,ko00624,ko00627,ko01120,ko01220,map00360,map00362,map00624,map00627,map01120,map01220 M00545 R01632,R03550,R04280,R04376,R06788,R09565 RC00233,RC00387,RC00535,RC01140,RC01364,RC02567,RC02694 br01602,ko00000,ko00001,ko00002,ko01000 - - - LigB CMS1_k127_511542_8 991905.SL003B_1109 5.934e-17 85.0 arCOG11629@1|root,331VF@2|Bacteria,1NFTA@1224|Proteobacteria,2UGD8@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Aromatic-ring-opening dioxygenase LigAB, LigA subunit - - - - - - - - - - - - LigA CMS1_k127_511542_1 231434.JQJH01000004_gene557 1.902e-178 569.0 COG1488@1|root,COG1488@2|Bacteria,1Q4UX@1224|Proteobacteria,2VB9P@28211|Alphaproteobacteria,3NC9T@45404|Beijerinckiaceae 28211|Alphaproteobacteria H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP - - - - - - - - - - - - NAPRTase CMS1_k127_511542_0 1380394.JADL01000004_gene6060 0.0 1010.0 COG4231@1|root,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,2TSHH@28211|Alphaproteobacteria,2JSZE@204441|Rhodospirillales 204441|Rhodospirillales C Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates - - - - - - - - - - - - TPP_enzyme_C CMS1_k127_511542_4 1380394.JADL01000004_gene6059 9.968e-119 404.0 COG1014@1|root,COG1014@2|Bacteria,1MV7Q@1224|Proteobacteria,2TTHE@28211|Alphaproteobacteria,2JQ2E@204441|Rhodospirillales 204441|Rhodospirillales C Pyruvate ferredoxin/flavodoxin oxidoreductase - - - - - - - - - - - - POR CMS1_k127_511542_5 1380394.JADL01000004_gene6058 9.464e-104 348.0 COG1638@1|root,COG1638@2|Bacteria,1NTFS@1224|Proteobacteria,2U1QM@28211|Alphaproteobacteria,2JXNJ@204441|Rhodospirillales 204441|Rhodospirillales G Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP CMS1_k127_511542_7 391624.OIHEL45_15219 1.078e-29 125.0 COG3090@1|root,COG3090@2|Bacteria,1RA8Q@1224|Proteobacteria,2U67A@28211|Alphaproteobacteria 28211|Alphaproteobacteria G TRAP-type C4-dicarboxylate transport system small permease component - - - - - - - - - - - - DctQ CMS1_k127_511542_2 1380394.JADL01000004_gene6056 2.878e-155 501.0 COG4664@1|root,COG4664@2|Bacteria,1QU8F@1224|Proteobacteria,2TYAS@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q Tripartite ATP-independent periplasmic transporter, DctM component - - - - - - - - - - - - DctM CMS1_k127_5133523_0 1380355.JNIJ01000006_gene3041 4.638e-145 467.0 COG3547@1|root,COG3547@2|Bacteria,1MUER@1224|Proteobacteria,2TQTP@28211|Alphaproteobacteria,3JR1M@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L PFAM transposase IS116 IS110 IS902 family - - - ko:K07486 - - - - ko00000 - - - DEDD_Tnp_IS110,Transposase_20 CMS1_k127_5175852_0 565033.GACE_0100 5.485e-90 309.0 COG5557@1|root,arCOG02025@2157|Archaea,2XWFI@28890|Euryarchaeota,246T1@183980|Archaeoglobi 183980|Archaeoglobi C PFAM Polysulphide reductase, NrfD - - - ko:K00185 - - - - ko00000 5.A.3 - - NrfD CMS1_k127_5175852_1 159087.Daro_3859 2.521e-46 182.0 COG3245@1|root,COG3245@2|Bacteria,1MZBZ@1224|Proteobacteria,2VMBB@28216|Betaproteobacteria,2KWMI@206389|Rhodocyclales 206389|Rhodocyclales C cytochrome c5 - - - - - - - - - - - - Cytochrome_CBB3 CMS1_k127_5175852_2 702113.PP1Y_AT23279 6.967e-22 108.0 2E92Z@1|root,333BY@2|Bacteria,1N8J4@1224|Proteobacteria,2UI81@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_5175852_3 553385.JEMF01000021_gene3070 1.772e-19 101.0 COG2863@1|root,COG2863@2|Bacteria,1N2NB@1224|Proteobacteria,1RZFP@1236|Gammaproteobacteria,1XI5C@135619|Oceanospirillales 135619|Oceanospirillales C COG2863 Cytochrome c553 cc4 - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 CMS1_k127_5175852_4 305900.GV64_02245 4.371e-13 81.0 COG2863@1|root,COG2863@2|Bacteria,1N2NB@1224|Proteobacteria,1RZFP@1236|Gammaproteobacteria,1XI5C@135619|Oceanospirillales 135619|Oceanospirillales C COG2863 Cytochrome c553 cc4 - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 CMS1_k127_5193681_3 670292.JH26_24305 2.009e-21 100.0 COG0655@1|root,COG0655@2|Bacteria,1MX6A@1224|Proteobacteria,2TU75@28211|Alphaproteobacteria,1JUA9@119045|Methylobacteriaceae 28211|Alphaproteobacteria S NADPH-dependent FMN reductase - - - - - - - - - - - - FMN_red CMS1_k127_5193681_0 1380355.JNIJ01000012_gene1019 9.429e-87 291.0 COG0330@1|root,COG1230@1|root,COG0330@2|Bacteria,COG1230@2|Bacteria,1MUSS@1224|Proteobacteria,2TQWX@28211|Alphaproteobacteria,3JVSY@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P Cation efflux family - - - - - - - - - - - - Cation_efflux CMS1_k127_5193681_2 1197906.CAJQ02000041_gene4831 3.453e-35 140.0 COG0599@1|root,COG0599@2|Bacteria,1RDSG@1224|Proteobacteria,2U72V@28211|Alphaproteobacteria,3JY3U@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Carboxymuconolactone decarboxylase family pcaC - 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 - R03470 RC00938 ko00000,ko00001,ko01000 - - - CMD CMS1_k127_5193681_4 1144319.PMI16_04448 7.729e-05 48.0 COG0599@1|root,COG2267@1|root,COG0599@2|Bacteria,COG2267@2|Bacteria,1MX0N@1224|Proteobacteria,2WHT8@28216|Betaproteobacteria,478N1@75682|Oxalobacteraceae 28216|Betaproteobacteria I TAP-like protein - - 3.1.1.24 ko:K01055 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00568 R02991 RC00825 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_1,CMD CMS1_k127_5193681_1 196490.AUEZ01000056_gene1044 2.95e-82 278.0 COG0596@1|root,COG0596@2|Bacteria,1QTTN@1224|Proteobacteria,2TRYE@28211|Alphaproteobacteria,3JRD7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Serine aminopeptidase, S33 MA20_09375 - 3.1.1.24 ko:K01055 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00568 R02991 RC00825 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_1 CMS1_k127_5204087_0 367336.OM2255_09576 5.266e-247 768.0 COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,2TRHQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria E glutamate synthase gltB - 1.4.1.13,1.4.1.14,1.4.7.1 ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 - R00021,R00093,R00114,R00248,R10086 RC00006,RC00010,RC02799 ko00000,ko00001,ko01000 - - - GATase_2,GXGXG,Glu_syn_central,Glu_synthase CMS1_k127_52101_1 113395.AXAI01000010_gene2157 2.147e-202 643.0 COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,2TRMA@28211|Alphaproteobacteria,3JV23@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P Belongs to the binding-protein-dependent transport system permease family urtB - - ko:K11960 ko02010,map02010 M00323 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4.4,3.A.1.4.5 - - BPD_transp_2 CMS1_k127_52101_0 426355.Mrad2831_1443 3.889e-234 731.0 COG0683@1|root,COG0683@2|Bacteria,1MU8V@1224|Proteobacteria,2TS3I@28211|Alphaproteobacteria,1JR7U@119045|Methylobacteriaceae 28211|Alphaproteobacteria E TIGRFAM urea ABC transporter, urea binding protein urtA - - ko:K11959 ko02010,map02010 M00323 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4.4,3.A.1.4.5 - - Peripla_BP_5 CMS1_k127_52101_3 1040989.AWZU01000007_gene699 7.477e-91 307.0 COG0715@1|root,COG0715@2|Bacteria,1PKQN@1224|Proteobacteria,2TSRB@28211|Alphaproteobacteria,3JUQJ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P 4,5-dihydroxyphthalate decarboxylase MA20_26650 - - - - - - - - - - - NMT1 CMS1_k127_52101_2 1304878.AUGD01000002_gene2146 2.874e-112 363.0 COG2120@1|root,COG2120@2|Bacteria,1MUTM@1224|Proteobacteria,2TSJ8@28211|Alphaproteobacteria,3JTMN@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S GlcNAc-PI de-N-acetylase MA20_26640 - 4.2.1.83 ko:K16515 ko00362,map00362 - R04478 RC00498 ko00000,ko00001,ko01000 - - - PIG-L CMS1_k127_532033_1 1038867.AXAY01000039_gene4548 2.454e-75 259.0 COG1121@1|root,COG1121@2|Bacteria,1MUDW@1224|Proteobacteria,2TQUI@28211|Alphaproteobacteria,3K375@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P AAA domain, putative AbiEii toxin, Type IV TA system - - - ko:K02074,ko:K09817 ko02010,map02010 M00242,M00244 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 - - ABC_tran CMS1_k127_532033_0 1038869.AXAN01000013_gene6227 2.666e-93 315.0 COG0803@1|root,COG0803@2|Bacteria,1MVW9@1224|Proteobacteria,2VHKN@28216|Betaproteobacteria,1K0PR@119060|Burkholderiaceae 28216|Betaproteobacteria P Belongs to the bacterial solute-binding protein 9 family - - - ko:K02077 - M00244 - - ko00000,ko00002,ko02000 3.A.1.15 - - ZnuA CMS1_k127_532033_2 1279038.KB907348_gene3100 8.226e-73 269.0 COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2TR2B@28211|Alphaproteobacteria,2JQWU@204441|Rhodospirillales 204441|Rhodospirillales O COG0790 FOG TPR repeat, SEL1 subfamily - - - ko:K07126 - - - - ko00000 - - - Sel1 CMS1_k127_532033_5 2340.JV46_17660 1.161e-08 68.0 COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1J4WE@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain degS GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009897,GO:0009986,GO:0009987,GO:0010033,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0033554,GO:0035966,GO:0035967,GO:0042221,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051716,GO:0051788,GO:0070011,GO:0070887,GO:0071218,GO:0071310,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564 - ko:K04691,ko:K04772 - - - - ko00000,ko01000,ko01002 - - - PDZ_2,Trypsin_2 CMS1_k127_532033_6 640512.BC1003_4901 8.103e-08 65.0 COG1262@1|root,COG4249@1|root,COG1262@2|Bacteria,COG4249@2|Bacteria,1NQ5K@1224|Proteobacteria,2VPHG@28216|Betaproteobacteria,1K230@119060|Burkholderiaceae 28216|Betaproteobacteria S peptidase C14 caspase catalytic subunit p20 - - - - - - - - - - - - FGE-sulfatase,Peptidase_C14 CMS1_k127_532033_4 1297570.MESS4_150014 8.364e-17 96.0 2DH1I@1|root,2ZY2R@2|Bacteria,1QY6F@1224|Proteobacteria,2TXI6@28211|Alphaproteobacteria,43MIQ@69277|Phyllobacteriaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_532033_3 991905.SL003B_3402 1.336e-47 196.0 2D4E5@1|root,32TGX@2|Bacteria,1N482@1224|Proteobacteria,2UE4H@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - ko:K20276 ko02024,map02024 - - - ko00000,ko00001 - - - - CMS1_k127_5324055_0 1125973.JNLC01000017_gene3601 1.124e-192 606.0 COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,2TQS1@28211|Alphaproteobacteria,3JRY2@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Signal transduction histidine kinase, nitrogen specific ntrB - 2.7.13.3 ko:K07708 ko02020,map02020 M00497 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_4 CMS1_k127_5324055_1 316056.RPC_2578 5.183e-115 372.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria,3JSFA@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Sigma-54 interaction domain ntrC - - ko:K07712 ko02020,map02020 M00497 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activ_2,Sigma54_activat CMS1_k127_5329766_2 1123508.JH636443_gene4982 2.365e-102 340.0 COG0491@1|root,COG0491@2|Bacteria,2IXNH@203682|Planctomycetes 203682|Planctomycetes S Metallo-beta-lactamase superfamily - - - - - - - - - - - - - CMS1_k127_5329766_3 709797.CSIRO_1381 5.053e-94 319.0 COG3820@1|root,COG3820@2|Bacteria,1MVR2@1224|Proteobacteria,2TT8Z@28211|Alphaproteobacteria,3JT5H@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF1013) MA20_20925 - - ko:K09987 - - - - ko00000 - - - DUF1013 CMS1_k127_5329766_1 1380355.JNIJ01000039_gene5354 8.292e-152 493.0 COG0761@1|root,COG0761@2|Bacteria,1MU7G@1224|Proteobacteria,2TRNR@28211|Alphaproteobacteria,3JSP9@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis ispH - 1.17.7.4 ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05884,R08210 RC01137,RC01487 ko00000,ko00001,ko00002,ko01000 - - - LYTB CMS1_k127_5329766_0 1297863.APJF01000022_gene4617 1.926e-156 498.0 COG2334@1|root,COG2334@2|Bacteria,1MUKJ@1224|Proteobacteria,2TS6D@28211|Alphaproteobacteria,3JQS5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria F Belongs to the pseudomonas-type ThrB family thrB - 2.7.1.39 ko:K02204 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - APH CMS1_k127_5329766_4 113395.AXAI01000005_gene3845 2.3e-70 256.0 COG0328@1|root,COG0328@2|Bacteria,1RCZ1@1224|Proteobacteria,2U7C4@28211|Alphaproteobacteria,3JTPP@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhA GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03469 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_H CMS1_k127_5329766_6 504832.OCAR_7328 1.171e-59 210.0 COG0678@1|root,COG0678@2|Bacteria,1MU0H@1224|Proteobacteria,2U6ZN@28211|Alphaproteobacteria,3JU03@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O Redoxin MA20_20905 - 1.11.1.15 ko:K03386 ko04214,map04214 - - - ko00000,ko00001,ko01000,ko04147 - - - Redoxin CMS1_k127_5329766_5 1411123.JQNH01000001_gene399 4.397e-63 220.0 COG0678@1|root,COG0678@2|Bacteria,1MU0H@1224|Proteobacteria,2U6ZN@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Peroxiredoxin MA20_20905 - 1.11.1.15 ko:K03386 ko04214,map04214 - - - ko00000,ko00001,ko01000,ko04147 - - - Redoxin CMS1_k127_5348358_1 84531.JMTZ01000096_gene717 4.156e-48 176.0 COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,1RQ1X@1236|Gammaproteobacteria,1X4PU@135614|Xanthomonadales 135614|Xanthomonadales C oxidoreductases (related to aryl-alcohol dehydrogenases) - - - - - - - - - - - - Aldo_ket_red CMS1_k127_5348358_0 1187851.A33M_0759 3.574e-99 331.0 COG2116@1|root,COG2116@2|Bacteria,1N8YM@1224|Proteobacteria,2U0ZN@28211|Alphaproteobacteria,3FE1K@34008|Rhodovulum 28211|Alphaproteobacteria P Formate/nitrite transporter yfdC - - ko:K21990 - - - - ko00000 1.A.16.4 - - Form_Nir_trans CMS1_k127_5392200_7 1336208.JADY01000004_gene3711 4.442e-88 307.0 COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,2TQUY@28211|Alphaproteobacteria,2JRCR@204441|Rhodospirillales 204441|Rhodospirillales S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B CMS1_k127_5392200_11 1123366.TH3_01920 2.291e-35 139.0 COG2259@1|root,COG2259@2|Bacteria,1RDYW@1224|Proteobacteria,2UCQJ@28211|Alphaproteobacteria,2JTCM@204441|Rhodospirillales 204441|Rhodospirillales S DoxX - - - ko:K15977 - - - - ko00000 - - - DoxX CMS1_k127_5392200_4 1411123.JQNH01000001_gene977 1.591e-160 511.0 COG0179@1|root,COG0179@2|Bacteria,1MV0V@1224|Proteobacteria,2TQYU@28211|Alphaproteobacteria 28211|Alphaproteobacteria Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) - - 3.7.1.2 ko:K16171 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R01364 RC00326,RC00446 ko00000,ko00001,ko00002,ko01000 - - - FAA_hydrolase CMS1_k127_5392200_2 1123229.AUBC01000019_gene4119 9.538e-244 757.0 COG3508@1|root,COG3508@2|Bacteria,1MV9G@1224|Proteobacteria,2TRFI@28211|Alphaproteobacteria,3JS7Y@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria Q Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate hmgA - 1.13.11.5 ko:K00451 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R02519 RC00737 ko00000,ko00001,ko00002,ko01000 - - - HgmA CMS1_k127_5392200_10 1380391.JIAS01000012_gene4084 1.602e-36 147.0 COG1846@1|root,COG1846@2|Bacteria,1N1CJ@1224|Proteobacteria,2UCHN@28211|Alphaproteobacteria,2JTEZ@204441|Rhodospirillales 204441|Rhodospirillales K helix_turn_helix multiple antibiotic resistance protein - - - - - - - - - - - - HTH_27,MarR,MarR_2 CMS1_k127_5392200_9 670292.JH26_07605 1.928e-79 270.0 COG0625@1|root,COG0625@2|Bacteria,1RA4Y@1224|Proteobacteria,2U5B6@28211|Alphaproteobacteria,1JR40@119045|Methylobacteriaceae 28211|Alphaproteobacteria O PFAM Glutathione S-transferase maiA - 5.2.1.2,5.2.1.4 ko:K01800,ko:K01801 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R03181,R03868 RC00867 ko00000,ko00001,ko00002,ko01000 - - - GST_C_2,GST_N,GST_N_3 CMS1_k127_5392200_8 670292.JH26_04830 1.756e-87 298.0 COG0697@1|root,COG0697@2|Bacteria,1MV7Y@1224|Proteobacteria,2TUVM@28211|Alphaproteobacteria,1JX63@119045|Methylobacteriaceae 28211|Alphaproteobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA CMS1_k127_5392200_6 258594.RPA1995 7.431e-91 312.0 2CKRE@1|root,32SCW@2|Bacteria,1MWRU@1224|Proteobacteria,2TSRM@28211|Alphaproteobacteria,3JQVC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF2865) - - - - - - - - - - - - DUF2865 CMS1_k127_5392200_0 1125973.JNLC01000002_gene2073 2.755e-266 833.0 COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,2TRAU@28211|Alphaproteobacteria,3JSE7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source nadE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5,6.3.5.1 ko:K01916,ko:K01950 ko00760,ko01100,map00760,map01100 M00115 R00189,R00257 RC00010,RC00100 ko00000,ko00001,ko00002,ko01000 - - - CN_hydrolase,NAD_synthase CMS1_k127_5392200_1 1040989.AWZU01000028_gene2961 3.876e-264 817.0 COG3200@1|root,COG3200@2|Bacteria,1MUWF@1224|Proteobacteria,2TR0E@28211|Alphaproteobacteria,3JUF8@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E phospho-2-dehydro-3-deoxyheptonate aldolase aroF GO:0003674,GO:0003824,GO:0003849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009507,GO:0009536,GO:0009611,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019438,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0050896,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 - - - DAHP_synth_2 CMS1_k127_5392200_3 1187851.A33M_1880 3.89e-203 641.0 COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,2TQS7@28211|Alphaproteobacteria,3FCRD@34008|Rhodovulum 28211|Alphaproteobacteria C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain gor GO:0000166,GO:0000302,GO:0000305,GO:0003674,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0010035,GO:0017076,GO:0019725,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0045454,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0065007,GO:0065008,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901700 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 - R00094,R00115 RC00011 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Pyr_redox_dim CMS1_k127_5392200_12 1197906.CAJQ02000016_gene142 7.611e-28 119.0 COG3184@1|root,COG3184@2|Bacteria,1RGVX@1224|Proteobacteria,2UBE3@28211|Alphaproteobacteria,3JSJU@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Uncharacterized protein conserved in bacteria (DUF2059) - - - ko:K09924 - - - - ko00000 - - - DUF2059 CMS1_k127_5392200_5 316058.RPB_3386 5.615e-97 322.0 COG0120@1|root,COG0120@2|Bacteria,1MVGR@1224|Proteobacteria,2TU68@28211|Alphaproteobacteria,3JTM0@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate rpiA - 5.3.1.6 ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167,M00580 R01056 RC00434 ko00000,ko00001,ko00002,ko01000 - - - Rib_5-P_isom_A CMS1_k127_5392200_15 443598.AUFA01000005_gene3961 1.336e-07 57.0 COG0546@1|root,COG0546@2|Bacteria,1RDDY@1224|Proteobacteria,2U79T@28211|Alphaproteobacteria,3JVBQ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress gph - 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 CMS1_k127_5392200_13 709797.CSIRO_2449 3.495e-19 94.0 2C6J4@1|root,2ZDBZ@2|Bacteria,1RHUG@1224|Proteobacteria,2U9TF@28211|Alphaproteobacteria,3JYMH@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - PEGA CMS1_k127_5392200_14 388739.RSK20926_16172 7.29e-14 75.0 COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,2TQQP@28211|Alphaproteobacteria,2P14X@2433|Roseobacter 28211|Alphaproteobacteria H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate moaA - 4.1.99.22 ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09394 RC03420 ko00000,ko00001,ko01000 - - - Fer4_12,Mob_synth_C,Radical_SAM CMS1_k127_5395642_0 460265.Mnod_1226 1.704e-130 421.0 COG3391@1|root,COG3391@2|Bacteria,1MXDX@1224|Proteobacteria,2TQRB@28211|Alphaproteobacteria,1JQZ4@119045|Methylobacteriaceae 28211|Alphaproteobacteria S 56kDa selenium binding protein (SBP56) - - - ko:K17285 - - - - ko00000,ko04147 - - - SBP56 CMS1_k127_5401723_11 504832.OCAR_7371 1.013e-20 100.0 2934B@1|root,2ZQMF@2|Bacteria,1R4T1@1224|Proteobacteria,2U1KR@28211|Alphaproteobacteria,3JU5Z@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_5401723_7 504832.OCAR_7372 3.064e-90 303.0 COG1238@1|root,COG1238@2|Bacteria,1MWED@1224|Proteobacteria,2U78A@28211|Alphaproteobacteria,3JRI3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S DedA family MA20_20865 - - - - - - - - - - - SNARE_assoc CMS1_k127_5401723_10 1230476.C207_02603 8.534e-39 150.0 COG0140@1|root,COG0140@2|Bacteria,1MZEE@1224|Proteobacteria,2U7W6@28211|Alphaproteobacteria,3JZ2R@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E phosphoribosyl-ATP diphosphatase activity MA20_20870 - 3.6.1.31 ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - PRA-PH CMS1_k127_5401723_0 1187851.A33M_4221 0.0 1305.0 COG0506@1|root,COG4230@1|root,COG0506@2|Bacteria,COG4230@2|Bacteria,1MV93@1224|Proteobacteria,2TQPT@28211|Alphaproteobacteria,3FDS7@34008|Rhodovulum 28211|Alphaproteobacteria CE Oxidizes proline to glutamate for use as a carbon and nitrogen source putA - 1.2.1.88,1.5.5.2 ko:K13821 ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130 - R00245,R00707,R00708,R01253,R04444,R04445,R05051 RC00080,RC00083,RC00216,RC00242,RC00255 ko00000,ko00001,ko01000,ko03000 - - - Aldedh,Pro_dh,Pro_dh-DNA_bdg CMS1_k127_5401723_5 1211115.ALIQ01000179_gene1575 1.069e-108 362.0 COG0715@1|root,COG0715@2|Bacteria,1MW53@1224|Proteobacteria,2TSHF@28211|Alphaproteobacteria 28211|Alphaproteobacteria P ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 CMS1_k127_5401723_9 1187851.A33M_4219 7.104e-58 215.0 COG0583@1|root,COG0583@2|Bacteria,1R9H4@1224|Proteobacteria,2U420@28211|Alphaproteobacteria 28211|Alphaproteobacteria K LysR substrate binding domain - - - - - - - - - - - - HTH_1,LysR_substrate CMS1_k127_5401723_2 1211115.ALIQ01000212_gene3294 2.12e-203 637.0 COG0183@1|root,COG0183@2|Bacteria,1MU8C@1224|Proteobacteria,2TS6P@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Belongs to the thiolase family MA20_27240 - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N CMS1_k127_5401723_4 316058.RPB_1345 6.753e-131 429.0 COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,2TT24@28211|Alphaproteobacteria,3JS1K@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Belongs to the peptidase S11 family dacA3 - 3.4.16.4 ko:K01286 - - - - ko00000,ko01000 - - - Peptidase_S11 CMS1_k127_5401723_3 1187851.A33M_4217 3.994e-154 501.0 COG0523@1|root,COG0523@2|Bacteria,1MVZV@1224|Proteobacteria,2TS4B@28211|Alphaproteobacteria,3FE5U@34008|Rhodovulum 28211|Alphaproteobacteria S Cobalamin synthesis protein cobW C-terminal domain p47K - - - - - - - - - - - CobW_C,cobW CMS1_k127_5401723_1 1040989.AWZU01000018_gene2819 1.419e-255 801.0 COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,3K2KD@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria IQ AMP-binding enzyme C-terminal domain - - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C CMS1_k127_5401723_8 883078.HMPREF9695_03981 1.916e-65 229.0 COG3803@1|root,COG3803@2|Bacteria,1RHYI@1224|Proteobacteria,2U7AN@28211|Alphaproteobacteria,3JW9E@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Bacterial protein of unknown function (DUF924) - - - - - - - - - - - - DUF924 CMS1_k127_5401723_6 292.DM42_3710 1.82e-107 361.0 COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2VM0P@28216|Betaproteobacteria,1K1QN@119060|Burkholderiaceae 28216|Betaproteobacteria P Belongs to the ABC transporter superfamily potA3 - 3.6.3.30 ko:K02010 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10 - - ABC_tran CMS1_k127_5411897_0 1380394.JADL01000005_gene5609 1.037e-141 454.0 COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,2TVZI@28211|Alphaproteobacteria,2JQ15@204441|Rhodospirillales 204441|Rhodospirillales C Formate dehydrogenase subunit alpha - - - - - - - - - - - - Fer2_4,Fer4_7,Fer4_9,Molybdop_Fe4S4,Molybdopterin,Molydop_binding CMS1_k127_5411897_3 269796.Rru_A3728 1.613e-70 255.0 COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,2VEYD@28211|Alphaproteobacteria,2JYKT@204441|Rhodospirillales 204441|Rhodospirillales E Receptor family ligand binding region - - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 CMS1_k127_5411897_5 1037409.BJ6T_44340 1.005e-18 89.0 2CIJJ@1|root,33GFX@2|Bacteria,1RJ9J@1224|Proteobacteria,2U9V7@28211|Alphaproteobacteria,3JZNN@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_5411897_1 5127.CCT68103 3.323e-127 422.0 COG1053@1|root,KOG2404@2759|Eukaryota,39V3W@33154|Opisthokonta,3NUD6@4751|Fungi,3QS1F@4890|Ascomycota,21B5H@147550|Sordariomycetes,3TUEQ@5125|Hypocreales,1FX8B@110618|Nectriaceae 4751|Fungi C FAD binding domain - - - - - - - - - - - - FAD_binding_2 CMS1_k127_5411897_4 883078.HMPREF9695_01450 3.217e-54 198.0 COG2863@1|root,COG2863@2|Bacteria,1N7W9@1224|Proteobacteria,2TSFV@28211|Alphaproteobacteria,3JRG8@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Cytochrome c - - - ko:K17230 ko00920,ko01120,map00920,map01120 - R09499 - ko00000,ko00001 - - - Cytochrom_C,Cytochrome_CBB3 CMS1_k127_5411897_2 1380355.JNIJ01000004_gene2836 4.361e-74 251.0 COG2133@1|root,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,2TRN9@28211|Alphaproteobacteria,3JTUJ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G Glucose / Sorbosone dehydrogenase - - - - - - - - - - - - GSDH,PBP CMS1_k127_5413043_4 1038859.AXAU01000010_gene1766 2.925e-87 288.0 COG3618@1|root,COG3618@2|Bacteria,1R4T9@1224|Proteobacteria,2TRFM@28211|Alphaproteobacteria,3JX2A@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Amidohydrolase - - - - - - - - - - - - Amidohydro_2 CMS1_k127_5413043_3 460265.Mnod_0218 1.387e-123 411.0 COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,2TS56@28211|Alphaproteobacteria,1JSFI@119045|Methylobacteriaceae 28211|Alphaproteobacteria J PFAM Amidase - - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase CMS1_k127_5413043_0 1123355.JHYO01000016_gene1850 3.19e-232 732.0 COG0388@1|root,COG1247@1|root,COG0388@2|Bacteria,COG1247@2|Bacteria,1MX4I@1224|Proteobacteria,2TVMQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - - - - - - - - - - Acetyltransf_1,CN_hydrolase CMS1_k127_5413043_1 1187851.A33M_1043 1.076e-160 514.0 COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,2TT0J@28211|Alphaproteobacteria,3FCTB@34008|Rhodovulum 28211|Alphaproteobacteria E Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls dapE - 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20 CMS1_k127_5413043_2 1187851.A33M_0258 6.407e-134 430.0 COG2171@1|root,COG2171@2|Bacteria,1MU0Y@1224|Proteobacteria,2TS3H@28211|Alphaproteobacteria,3FCJ9@34008|Rhodovulum 28211|Alphaproteobacteria E Tetrahydrodipicolinate N-succinyltransferase N-terminal dapD - 2.3.1.117 ko:K00674 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R04365 RC00004,RC01136 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,Hexapep_2,THDPS_N_2 CMS1_k127_5432084_8 69279.BG36_15990 4.769e-112 374.0 COG1752@1|root,COG1752@2|Bacteria,1MWH2@1224|Proteobacteria,2TU16@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF3376) - - - - - - - - - - - - DUF3376,Patatin CMS1_k127_5432084_7 316055.RPE_0478 1.711e-119 389.0 COG2041@1|root,COG2041@2|Bacteria,1MUW0@1224|Proteobacteria,2TS40@28211|Alphaproteobacteria,3JSIU@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Oxidoreductase molybdopterin binding MA20_43580 - - - - - - - - - - - Oxidored_molyb,TAT_signal CMS1_k127_5432084_10 1038860.AXAP01000026_gene1730 2.442e-94 312.0 COG4117@1|root,COG4117@2|Bacteria,1MX97@1224|Proteobacteria,2U0ZF@28211|Alphaproteobacteria,3JSZD@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Prokaryotic cytochrome b561 MA20_43575 - - - - - - - - - - - Ni_hydr_CYTB CMS1_k127_5432084_22 1197906.CAJQ02000011_gene809 4.435e-09 63.0 2EMTK@1|root,33FFY@2|Bacteria,1N44C@1224|Proteobacteria,2UDYR@28211|Alphaproteobacteria,3K0VH@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S TIGRFAM pentapeptide MXKDX repeat protein MA20_30155 - - - - - - - - - - - - CMS1_k127_5432084_3 1187851.A33M_2084 8.809e-168 537.0 COG2030@1|root,COG2030@2|Bacteria,1MW4N@1224|Proteobacteria,2TQQ2@28211|Alphaproteobacteria,3FCJ5@34008|Rhodovulum 28211|Alphaproteobacteria I dehydratase mch GO:0003674,GO:0003824,GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0016999,GO:0017001,GO:0017144,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0045733,GO:0046395,GO:0071704,GO:0072329,GO:1901575 4.2.1.148 ko:K14449 ko00630,ko00660,ko00720,ko01120,ko01200,map00630,map00660,map00720,map01120,map01200 M00373,M00376,M00740 R05076 RC01984 ko00000,ko00001,ko00002,ko01000 - - - MaoC_dehydrat_N,MaoC_dehydratas CMS1_k127_5432084_15 1231185.BAMP01000081_gene3657 4.623e-46 176.0 COG2329@1|root,COG2329@2|Bacteria,1RGVV@1224|Proteobacteria,2U9A3@28211|Alphaproteobacteria,43KD2@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Involved in biosynthesis of extracellular polysaccharides MA20_35560 - - - - - - - - - - - ABM CMS1_k127_5432084_6 670292.JH26_25285 5.52e-131 423.0 COG0583@1|root,COG0583@2|Bacteria,1N3XX@1224|Proteobacteria,2TS9T@28211|Alphaproteobacteria,1JRNG@119045|Methylobacteriaceae 28211|Alphaproteobacteria K PFAM regulatory protein LysR - - - ko:K11921 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate CMS1_k127_5432084_14 1120983.KB894573_gene359 5.773e-52 187.0 COG2009@1|root,COG2009@2|Bacteria,1N02N@1224|Proteobacteria,2UC47@28211|Alphaproteobacteria,1JPAU@119043|Rhodobiaceae 28211|Alphaproteobacteria C Succinate dehydrogenase/Fumarate reductase transmembrane subunit sdhC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002 - - - Sdh_cyt CMS1_k127_5432084_18 1429916.X566_10020 4.619e-33 139.0 COG2142@1|root,COG2142@2|Bacteria,1MZND@1224|Proteobacteria,2UC3G@28211|Alphaproteobacteria,3JYRC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C succinate dehydrogenase sdhD - - ko:K00242 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173 R02164 RC00045 ko00000,ko00001,ko00002 - - - Sdh_cyt CMS1_k127_5432084_0 1502851.FG93_05917 0.0 1024.0 COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,2TQJA@28211|Alphaproteobacteria,3JR6R@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily sdhA - 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C CMS1_k127_5432084_4 366394.Smed_2956 2.692e-145 463.0 COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,2TQYF@28211|Alphaproteobacteria,4B9NK@82115|Rhizobiaceae 28211|Alphaproteobacteria C Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family sdhB - 1.3.5.1,1.3.5.4 ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - Fer2_3,Fer4_10,Fer4_17,Fer4_8 CMS1_k127_5432084_12 1028800.RG540_PA08940 1.411e-65 226.0 COG5485@1|root,COG5485@2|Bacteria,1N1VS@1224|Proteobacteria,2UG41@28211|Alphaproteobacteria 28211|Alphaproteobacteria S SnoaL-like polyketide cyclase - - - - - - - - - - - - SnoaL CMS1_k127_5432084_16 583345.Mmol_0710 7.36e-45 178.0 COG0501@1|root,COG0501@2|Bacteria,1RH15@1224|Proteobacteria,2VZ68@28216|Betaproteobacteria,2KNT2@206350|Nitrosomonadales 206350|Nitrosomonadales M Domain present in PSD-95, Dlg, and ZO-1/2. - - - - - - - - - - - - PDZ_2,Peptidase_M48 CMS1_k127_5432084_21 1429916.X566_23550 1.576e-12 77.0 2A8UK@1|root,30XXU@2|Bacteria,1RHB8@1224|Proteobacteria,2U9EM@28211|Alphaproteobacteria,3JZUA@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_5432084_1 1380355.JNIJ01000019_gene4656 1.651e-239 748.0 COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,2TTGS@28211|Alphaproteobacteria,3JRAJ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Belongs to the argininosuccinate synthase family. Type 2 subfamily argG GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 M00029,M00844,M00845 R01954 RC00380,RC00629 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Arginosuc_synth CMS1_k127_5432084_9 663610.JQKO01000002_gene1170 1.615e-100 337.0 COG2951@1|root,COG2951@2|Bacteria,1MVY0@1224|Proteobacteria,2TTVI@28211|Alphaproteobacteria,3N9WS@45404|Beijerinckiaceae 28211|Alphaproteobacteria M Transglycosylase SLT domain MA20_41385 - - - - - - - - - - - SLT_2 CMS1_k127_5432084_11 196490.AUEZ01000023_gene7132 3.093e-77 267.0 COG0671@1|root,COG0671@2|Bacteria,1N4GM@1224|Proteobacteria,2TURF@28211|Alphaproteobacteria,3JRG0@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I PAP2 superfamily MA20_43480 - - ko:K12978 - - - - ko00000,ko01000,ko01005 - - - PAP2 CMS1_k127_5432084_20 288000.BBta_0240 5.115e-18 89.0 2C8HF@1|root,2ZXE6@2|Bacteria,1R5PH@1224|Proteobacteria,2U64K@28211|Alphaproteobacteria,3JYIK@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - MA20_43475 - - - - - - - - - - - - CMS1_k127_5432084_2 114615.BRADO0246 6.329e-209 655.0 COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,2TQT3@28211|Alphaproteobacteria,3JUHU@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs rlmN GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 ko:K06941 - - - - ko00000,ko01000,ko03009 - - - Radical_SAM CMS1_k127_5432084_13 1380355.JNIJ01000019_gene4652 5.965e-54 194.0 COG5342@1|root,COG5342@2|Bacteria,1R46Z@1224|Proteobacteria,2U5KW@28211|Alphaproteobacteria,3JVKM@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S invasion associated locus B - - - - - - - - - - - - - CMS1_k127_5432084_5 443598.AUFA01000038_gene5058 3.546e-135 437.0 COG0604@1|root,COG0604@2|Bacteria,1MWRK@1224|Proteobacteria,2TQMF@28211|Alphaproteobacteria,3JRI0@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Zinc-binding dehydrogenase MA20_25320 - 1.1.1.1,1.6.5.5 ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N CMS1_k127_5432084_17 883078.HMPREF9695_04724 3.391e-36 140.0 COG3339@1|root,COG3339@2|Bacteria,1MZR5@1224|Proteobacteria,2UCIB@28211|Alphaproteobacteria,3JYQE@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF1232) MA20_25305 - - - - - - - - - - - DUF1232 CMS1_k127_5438292_0 1157708.KB907462_gene1030 4.389e-243 763.0 COG2936@1|root,COG2936@2|Bacteria,1MVA8@1224|Proteobacteria,2VTNQ@28216|Betaproteobacteria 28216|Betaproteobacteria S X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain - - - ko:K06978 - - - - ko00000 - - - PepX_C,Peptidase_S15 CMS1_k127_5438292_6 1394178.AWOO02000009_gene4270 2.323e-23 105.0 COG0251@1|root,COG0251@2|Bacteria,2IIMX@201174|Actinobacteria 201174|Actinobacteria J Endoribonuclease L-PSP - - 3.5.99.10 ko:K09022 - - R11098,R11099 RC03275,RC03354 ko00000,ko01000 - - - Ribonuc_L-PSP CMS1_k127_5438292_3 1286093.C266_02456 1.826e-63 228.0 COG0600@1|root,COG0600@2|Bacteria,1MVAE@1224|Proteobacteria,2VPSG@28216|Betaproteobacteria,1KGD1@119060|Burkholderiaceae 28216|Betaproteobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K02050 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - BPD_transp_1 CMS1_k127_5438292_2 1463855.JOHV01000036_gene5805 7.849e-85 290.0 COG1116@1|root,COG1116@2|Bacteria,2GN33@201174|Actinobacteria 201174|Actinobacteria P ABC transporter - - - ko:K02049 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - ABC_tran CMS1_k127_5438292_4 977880.RALTA_A0572 3.035e-38 156.0 COG0583@1|root,COG0583@2|Bacteria,1R8E9@1224|Proteobacteria,2VIAT@28216|Betaproteobacteria,1K6A8@119060|Burkholderiaceae 28216|Betaproteobacteria K Transcriptional regulator - - - ko:K19338 - - - - ko00000,ko03000 - - - HTH_1,LysR_substrate CMS1_k127_5438292_5 1229205.BUPH_02661 1.2e-29 132.0 COG0715@1|root,COG0715@2|Bacteria,1R60E@1224|Proteobacteria,2W4Q0@28216|Betaproteobacteria,1K6HY@119060|Burkholderiaceae 28216|Betaproteobacteria P ABC transporter, phosphonate, periplasmic substrate-binding protein - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 CMS1_k127_5438292_1 1122917.KB899675_gene241 1.09e-100 347.0 COG2141@1|root,COG2141@2|Bacteria,1TQZ0@1239|Firmicutes,4HAF9@91061|Bacilli,26W5G@186822|Paenibacillaceae 91061|Bacilli C Luciferase-like monooxygenase dmoA - 1.14.14.28 ko:K20938 - - - - ko00000,ko01000 - - - Bac_luciferase CMS1_k127_5438292_7 314225.ELI_14895 3.672e-10 62.0 COG2963@1|root,COG2963@2|Bacteria,1RGZ5@1224|Proteobacteria,2UAIS@28211|Alphaproteobacteria,2K5CA@204457|Sphingomonadales 204457|Sphingomonadales L COG2801 Transposase and inactivated derivatives - - - - - - - - - - - - HTH_Tnp_1 CMS1_k127_5449243_20 107636.JQNK01000002_gene549 4.112e-20 91.0 COG1051@1|root,COG1051@2|Bacteria,1N0YW@1224|Proteobacteria,2UC2E@28211|Alphaproteobacteria,36YKX@31993|Methylocystaceae 28211|Alphaproteobacteria F NUDIX domain - - - - - - - - - - - - NUDIX CMS1_k127_5449243_22 93220.LV28_01850 6.263e-11 72.0 2EIQJ@1|root,33CG0@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - CMS1_k127_5449243_21 426114.THI_1991 2.736e-13 74.0 COG3462@1|root,COG3462@2|Bacteria,1NGXC@1224|Proteobacteria,2VY74@28216|Betaproteobacteria 28216|Betaproteobacteria S Short C-terminal domain - - - ko:K08982 - - - - ko00000 - - - SHOCT CMS1_k127_5449243_7 1187851.A33M_3000 2.094e-140 452.0 COG0435@1|root,COG0435@2|Bacteria,1MV50@1224|Proteobacteria,2TRDE@28211|Alphaproteobacteria,3FCKK@34008|Rhodovulum 28211|Alphaproteobacteria O Glutathione S-transferase, C-terminal domain yqjG GO:0003674,GO:0003824,GO:0004364,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0016491,GO:0016667,GO:0016672,GO:0016740,GO:0016765,GO:0042221,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.5.7 ko:K07393 - - - - ko00000,ko01000 - - - GST_C_2,GST_N_2 CMS1_k127_5449243_14 323097.Nham_3258 1.005e-74 256.0 COG3153@1|root,COG3153@2|Bacteria,1RD0C@1224|Proteobacteria,2U7AS@28211|Alphaproteobacteria,3JTBQ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_9 CMS1_k127_5449243_1 1187851.A33M_2998 0.0 1006.0 COG5426@1|root,COG5426@2|Bacteria,1MVWA@1224|Proteobacteria,2TQNQ@28211|Alphaproteobacteria,3FCSI@34008|Rhodovulum 28211|Alphaproteobacteria S membrane MA20_44660 - - - - - - - - - - - GATase1_like CMS1_k127_5449243_0 1187851.A33M_2997 0.0 1259.0 28H8H@1|root,2Z7KE@2|Bacteria,1MV77@1224|Proteobacteria,2TSVV@28211|Alphaproteobacteria,3FCM7@34008|Rhodovulum 28211|Alphaproteobacteria S Aerotolerance regulator N-terminal MA20_44655 - - - - - - - - - - - BatA,DUF4159 CMS1_k127_5449243_8 1187851.A33M_2996 1.606e-135 437.0 COG1721@1|root,COG1721@2|Bacteria,1MWPG@1224|Proteobacteria,2TTDX@28211|Alphaproteobacteria,3FD5D@34008|Rhodovulum 28211|Alphaproteobacteria S Protein of unknown function DUF58 MA20_44650 - - - - - - - - - - - DUF58 CMS1_k127_5449243_3 1040989.AWZU01000009_gene1139 2.264e-175 556.0 COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,2TR0T@28211|Alphaproteobacteria,3JTNE@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ATPase family associated with various cellular activities (AAA) moxR GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 CMS1_k127_5449243_13 114615.BRADO1965 1.902e-75 258.0 COG3816@1|root,COG3816@2|Bacteria,1RD5Q@1224|Proteobacteria,2U7DA@28211|Alphaproteobacteria,3JSDP@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF1285) MA20_44640 - - ko:K09986 - - - - ko00000 - - - DUF1285 CMS1_k127_5449243_11 1038862.KB893917_gene4455 3.173e-81 281.0 COG0494@1|root,COG0494@2|Bacteria,1RD2C@1224|Proteobacteria,2TV3Q@28211|Alphaproteobacteria,3JU9N@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L NUDIX domain MA20_44635 - - - - - - - - - - - NUDIX CMS1_k127_5449243_19 1038860.AXAP01000064_gene4000 1.015e-22 102.0 2CETE@1|root,32ZH4@2|Bacteria,1N1NH@1224|Proteobacteria,2UBYE@28211|Alphaproteobacteria,3K03U@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_5449243_6 652103.Rpdx1_1359 5.395e-155 500.0 COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,2TRPZ@28211|Alphaproteobacteria,3JR2K@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Poly A polymerase head domain pcnB - 2.7.7.19,2.7.7.72 ko:K00970,ko:K00974 ko03013,ko03018,map03013,map03018 - R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016,ko03019 - - - PolyA_pol,PolyA_pol_RNAbd CMS1_k127_5449243_18 316058.RPB_0699 1.946e-24 104.0 2C0Z1@1|root,32Y66@2|Bacteria,1N9AH@1224|Proteobacteria,2UFBQ@28211|Alphaproteobacteria,3K07K@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_5449243_15 420324.KI912069_gene6356 4.87e-65 226.0 COG1672@1|root,COG1672@2|Bacteria,1N05N@1224|Proteobacteria,2UBUA@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Electron transfer DM13 - - - - - - - - - - - - DM13 CMS1_k127_5449243_12 1297865.APJD01000007_gene1934 8.481e-79 279.0 COG0730@1|root,COG0730@2|Bacteria,1MUJB@1224|Proteobacteria,2TRWP@28211|Alphaproteobacteria,3JT50@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Sulfite exporter TauE/SafE MA20_44620 - - ko:K07090 - - - - ko00000 - - - TauE CMS1_k127_5449243_4 1040989.AWZU01000009_gene1134 8.389e-162 512.0 COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,2TQNC@28211|Alphaproteobacteria,3JRIR@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX hemF GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 ko:K00228 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R03220 RC00884 ko00000,ko00001,ko00002,ko01000 - - - Coprogen_oxidas CMS1_k127_5449243_16 1245469.S58_55730 1.606e-60 216.0 COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,2U78W@28211|Alphaproteobacteria,3JYG0@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide trmL - 2.1.1.207 ko:K03216 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase CMS1_k127_5449243_10 1187851.A33M_1238 1.279e-87 291.0 COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,2TTT2@28211|Alphaproteobacteria,3FD3W@34008|Rhodovulum 28211|Alphaproteobacteria C Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis petA - 1.10.2.2 ko:K00411 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 - - ko00000,ko00001,ko00002,ko01000 - - - Rieske,UCR_Fe-S_N CMS1_k127_5449243_2 504832.OCAR_6995 2.48e-220 688.0 COG1290@1|root,COG2857@1|root,COG1290@2|Bacteria,COG2857@2|Bacteria,1MV97@1224|Proteobacteria,2TSZ3@28211|Alphaproteobacteria,3JUWH@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis petB - - ko:K00410,ko:K00412 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 - - ko00000,ko00001,ko00002,ko03029 - - - Cytochrom_B_C,Cytochrom_C1,Cytochrome_B CMS1_k127_5449243_9 666684.AfiDRAFT_2969 6.241e-110 369.0 COG1290@1|root,COG2857@1|root,COG1290@2|Bacteria,COG2857@2|Bacteria,1MV97@1224|Proteobacteria,2TSZ3@28211|Alphaproteobacteria,3JUWH@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis petB - - ko:K00410,ko:K00412 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 - - ko00000,ko00001,ko00002,ko03029 - - - Cytochrom_B_C,Cytochrom_C1,Cytochrome_B CMS1_k127_5449243_5 196490.AUEZ01000050_gene350 7.054e-161 511.0 COG0005@1|root,COG0005@2|Bacteria,1MUWW@1224|Proteobacteria,2TSN3@28211|Alphaproteobacteria,3JS3B@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria F Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates mtnP - 2.4.2.28 ko:K00772 ko00270,ko01100,map00270,map01100 M00034 R01402 RC00063,RC02819 ko00000,ko00001,ko00002,ko01000 - - - PNP_UDP_1 CMS1_k127_5449243_17 1187851.A33M_0002 2.289e-54 196.0 COG0503@1|root,COG0503@2|Bacteria,1MVZ6@1224|Proteobacteria,2TV7J@28211|Alphaproteobacteria,3FD12@34008|Rhodovulum 28211|Alphaproteobacteria F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis apt - 2.4.2.7 ko:K00759 ko00230,ko01100,map00230,map01100 - R00190,R01229,R04378 RC00063 ko00000,ko00001,ko01000,ko04147 - - - Pribosyltran CMS1_k127_5452265_13 78245.Xaut_0462 6.362e-58 203.0 COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,2TQW1@28211|Alphaproteobacteria,3EYF9@335928|Xanthobacteraceae 28211|Alphaproteobacteria C C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex ccoP - - ko:K00406 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - Cytochrome_CBB3,FixP_N CMS1_k127_5452265_16 1125973.JNLC01000010_gene1619 3.289e-14 79.0 COG4736@1|root,COG4736@2|Bacteria 2|Bacteria O Cbb3-type cytochrome oxidase ccoQ - - ko:K00407 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - FixQ CMS1_k127_5452265_3 864069.MicloDRAFT_00022660 7.606e-127 409.0 COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,2TRGW@28211|Alphaproteobacteria,1JTMI@119045|Methylobacteriaceae 28211|Alphaproteobacteria C PFAM cytochrome C oxidase mono-heme subunit FixO ccoO - - ko:K00405 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002 3.D.4.3 - - FixO CMS1_k127_5452265_0 670292.JH26_01485 3.014e-319 983.0 COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,2TR2C@28211|Alphaproteobacteria,1JUD2@119045|Methylobacteriaceae 28211|Alphaproteobacteria O TIGRFAM cytochrome c oxidase, cbb3-type, subunit I ccoN GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 ko:K00404 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00156 - - ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - COX1 CMS1_k127_5452265_12 666684.AfiDRAFT_0660 5.672e-58 207.0 COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,2UFRX@28211|Alphaproteobacteria,3JYE3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O Hsp20/alpha crystallin family - - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 CMS1_k127_5452265_2 479432.Sros_7299 2.239e-159 527.0 COG1233@1|root,COG1233@2|Bacteria,2GJ80@201174|Actinobacteria,4EQV7@85012|Streptosporangiales 201174|Actinobacteria Q Flavin containing amine oxidoreductase - - - - - - - - - - - - Amino_oxidase,NAD_binding_8 CMS1_k127_5452265_8 196490.AUEZ01000039_gene7055 5.881e-75 258.0 COG0664@1|root,COG0664@2|Bacteria,1MVGE@1224|Proteobacteria,2U36S@28211|Alphaproteobacteria,3JTBY@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K Crp Fnr family fixK - - ko:K01420,ko:K15861 ko02020,map02020 - - - ko00000,ko00001,ko03000 - - - HTH_Crp_2,cNMP_binding CMS1_k127_5452265_1 450851.PHZ_c2803 8.726e-179 574.0 COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TR8X@28211|Alphaproteobacteria,2KG47@204458|Caulobacterales 204458|Caulobacterales T Histidine kinase - - 2.7.13.3 ko:K14986 ko02020,map02020 M00524 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS CMS1_k127_5452265_9 420324.KI911947_gene5617 2.141e-74 255.0 COG4566@1|root,COG4566@2|Bacteria,1N6WR@1224|Proteobacteria,2TUND@28211|Alphaproteobacteria,1JUHX@119045|Methylobacteriaceae 28211|Alphaproteobacteria K response regulator fixJ - - ko:K14987 ko02020,map02020 M00524 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg CMS1_k127_5452265_7 1123060.JONP01000028_gene3676 2.938e-76 267.0 COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,2TQQG@28211|Alphaproteobacteria,2JPZ1@204441|Rhodospirillales 204441|Rhodospirillales Q Fumarylacetoacetate (FAA) hydrolase family - - - - - - - - - - - - FAA_hydrolase CMS1_k127_5452265_4 311403.Arad_7260 3.955e-115 379.0 COG0346@1|root,COG0346@2|Bacteria,1PK3Q@1224|Proteobacteria,2U2PI@28211|Alphaproteobacteria,4BCQD@82115|Rhizobiaceae 28211|Alphaproteobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase CMS1_k127_5452265_11 1419583.V466_11175 1.33e-64 231.0 COG2084@1|root,COG2084@2|Bacteria,1R889@1224|Proteobacteria 1224|Proteobacteria I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - 1.1.1.31 ko:K00020 ko00280,ko01100,map00280,map01100 - R05066 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 CMS1_k127_5452265_14 883080.HMPREF9697_01896 7.851e-55 207.0 COG4948@1|root,COG4948@2|Bacteria,1MU8R@1224|Proteobacteria,2TSS4@28211|Alphaproteobacteria,3JRRK@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Mandelate racemase / muconate lactonizing enzyme, C-terminal domain catB - 5.1.1.20,5.5.1.1,5.5.1.7 ko:K01856,ko:K01860,ko:K19802 ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220 M00568 R04259,R05300,R05390,R05392,R06834,R06840,R06989,R08116,R08119,R09135,R09215,R09217,R09221,R09229,R10938 RC00903,RC01038,RC01108,RC01321,RC01356,RC01358,RC01687,RC02117,RC02448,RC02464,RC02465,RC03309 ko00000,ko00001,ko00002,ko01000 - - - MR_MLE_C,MR_MLE_N CMS1_k127_5452265_6 1205680.CAKO01000037_gene1184 1.066e-98 332.0 COG0491@1|root,COG0491@2|Bacteria,1N22F@1224|Proteobacteria,2U2V5@28211|Alphaproteobacteria,2JVNG@204441|Rhodospirillales 204441|Rhodospirillales S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B CMS1_k127_5452265_15 324057.Pjdr2_3112 5.85e-24 106.0 COG1028@1|root,COG1028@2|Bacteria,1U2GS@1239|Firmicutes,4H9R9@91061|Bacilli,26QGX@186822|Paenibacillaceae 91061|Bacilli IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - - - - - - - - - - adh_short_C2 CMS1_k127_5452265_10 666684.AfiDRAFT_3149 1.34e-66 238.0 COG1028@1|root,COG1028@2|Bacteria,1NBB6@1224|Proteobacteria,2TVF5@28211|Alphaproteobacteria,3JXK5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria IQ Enoyl-(Acyl carrier protein) reductase - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short,adh_short_C2 CMS1_k127_5452265_5 1121028.ARQE01000009_gene4037 3.939e-103 349.0 COG1042@1|root,COG1670@1|root,COG1042@2|Bacteria,COG1670@2|Bacteria,1MW98@1224|Proteobacteria,2TR24@28211|Alphaproteobacteria,2PKI2@255475|Aurantimonadaceae 28211|Alphaproteobacteria C CoA binding domain yfiQ - - ko:K09181 - - - - ko00000 - - - ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig CMS1_k127_5459872_1 1187851.A33M_1747 6.191e-226 706.0 COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2TR2Z@28211|Alphaproteobacteria,3FCU3@34008|Rhodovulum 28211|Alphaproteobacteria C FAD linked oxidases, C-terminal domain dld GO:0003674,GO:0003824,GO:0004457,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008720,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046034,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.1.1.303,1.1.1.4,1.1.2.4 ko:K00004,ko:K00102 ko00620,ko00650,map00620,map00650 - R00197,R02855,R02946,R10504 RC00044,RC00205,RC00525 ko00000,ko00001,ko01000 - - - FAD-oxidase_C,FAD_binding_4 CMS1_k127_5459872_3 1429916.X566_00790 3.77e-187 630.0 COG2982@1|root,COG2982@2|Bacteria,1MUNH@1224|Proteobacteria,2TT0W@28211|Alphaproteobacteria,3JRU3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M AsmA-like C-terminal region asmA - - ko:K07289 - - - - ko00000 - - - AsmA,AsmA_2 CMS1_k127_5459872_7 1187851.A33M_1125 1.244e-29 120.0 COG4321@1|root,COG4321@2|Bacteria,1N7Z2@1224|Proteobacteria,2UF7W@28211|Alphaproteobacteria,3FDI9@34008|Rhodovulum 28211|Alphaproteobacteria S Ribbon-helix-helix domain MA20_02235 - - - - - - - - - - - RHH_4 CMS1_k127_5459872_0 1040989.AWZU01000002_gene5399 1.195e-226 711.0 COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,2TQM7@28211|Alphaproteobacteria,3JV56@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate fumC GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 M00009,M00011,M00173,M00376 R01082 RC00443 ko00000,ko00001,ko00002,ko01000 - - - FumaraseC_C,Lyase_1 CMS1_k127_5459872_6 1187851.A33M_1128 1.896e-58 207.0 COG3814@1|root,COG3814@2|Bacteria,1N1FE@1224|Proteobacteria,2U7H9@28211|Alphaproteobacteria,3FDB1@34008|Rhodovulum 28211|Alphaproteobacteria S Stringent starvation protein B MA20_02250 - - ko:K09985 - - - - ko00000 - - - SspB CMS1_k127_5459872_5 1120983.KB894572_gene2922 2.355e-72 252.0 COG2021@1|root,COG2021@2|Bacteria,1QU84@1224|Proteobacteria,2TXRG@28211|Alphaproteobacteria 28211|Alphaproteobacteria E alpha/beta hydrolase fold - - 3.1.1.24 ko:K01055 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00568 R02991 RC00825 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_1 CMS1_k127_5459872_2 1187851.A33M_0129 5.187e-201 641.0 COG0668@1|root,COG0668@2|Bacteria,1R2TK@1224|Proteobacteria,2TZRG@28211|Alphaproteobacteria,3FEH0@34008|Rhodovulum 28211|Alphaproteobacteria M Mechanosensitive ion channel - - - - - - - - - - - - MS_channel CMS1_k127_5459872_4 1297863.APJF01000006_gene1181 4.111e-107 363.0 COG4249@1|root,COG4249@2|Bacteria,1MXFD@1224|Proteobacteria,2TRW5@28211|Alphaproteobacteria,3JQPH@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Caspase domain - - - - - - - - - - - - Peptidase_C14 CMS1_k127_5461638_9 543728.Vapar_5778 4.6e-53 199.0 COG0500@1|root,COG2226@2|Bacteria,1PG85@1224|Proteobacteria,2WC4M@28216|Betaproteobacteria,4AIUN@80864|Comamonadaceae 28216|Betaproteobacteria H ubiE/COQ5 methyltransferase family - - - - - - - - - - - - Methyltransf_11 CMS1_k127_5461638_7 318996.AXAZ01000043_gene2086 2.973e-109 359.0 COG0500@1|root,COG2226@2|Bacteria,1R79J@1224|Proteobacteria,2U421@28211|Alphaproteobacteria,3JVA3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria Q ubiE/COQ5 methyltransferase family - - - - - - - - - - - - Methyltransf_11 CMS1_k127_5461638_14 1038860.AXAP01000167_gene311 8.855e-10 61.0 COG3293@1|root,COG3293@2|Bacteria,1P5HD@1224|Proteobacteria,2TUQI@28211|Alphaproteobacteria,3JYMC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L Transposase DDE domain - - - - - - - - - - - - DDE_Tnp_1_2,DUF4096 CMS1_k127_5461638_10 709797.CSIRO_2230 5.141e-51 186.0 COG1042@1|root,COG1670@1|root,COG1042@2|Bacteria,COG1670@2|Bacteria,1MW98@1224|Proteobacteria,2TR24@28211|Alphaproteobacteria,3JR42@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria CJ ATP-grasp domain - - - ko:K09181 - - - - ko00000 - - - ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig CMS1_k127_5461638_8 1187851.A33M_3151 5.339e-102 339.0 COG0589@1|root,COG0589@2|Bacteria,1QD8E@1224|Proteobacteria,2TRQ7@28211|Alphaproteobacteria,3FDDE@34008|Rhodovulum 28211|Alphaproteobacteria T Universal stress protein family - - - - - - - - - - - - Usp CMS1_k127_5461638_11 319003.Bra1253DRAFT_04029 1.908e-47 173.0 COG3474@1|root,COG3474@2|Bacteria,1MZGS@1224|Proteobacteria,2UCUT@28211|Alphaproteobacteria,3JY3A@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Cytochrome c cycA GO:0005575,GO:0005623,GO:0042597,GO:0044464 - ko:K08738 ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.6 - - Cytochrom_C CMS1_k127_5461638_0 316058.RPB_1827 3.746e-268 831.0 COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2TSG6@28211|Alphaproteobacteria,3JRIA@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C FAD linked oxidases, C-terminal domain glcD - 1.1.3.15 ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001,ko01000 - - - FAD-oxidase_C,FAD_binding_4 CMS1_k127_5461638_4 886293.Sinac_3820 1.318e-154 494.0 COG2141@1|root,COG2141@2|Bacteria,2J10P@203682|Planctomycetes 203682|Planctomycetes C Luciferase-like monooxygenase - - - - - - - - - - - - Bac_luciferase CMS1_k127_5461638_6 1187851.A33M_3149 1.19e-148 480.0 COG0277@1|root,COG0277@2|Bacteria,1MVYV@1224|Proteobacteria,2TRA7@28211|Alphaproteobacteria,3FCYE@34008|Rhodovulum 28211|Alphaproteobacteria C FAD binding domain glcE - - ko:K11472 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001 - - - FAD-oxidase_C,FAD_binding_4 CMS1_k127_5461638_2 991905.SL003B_3474 1.01e-185 589.0 COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,2TR9H@28211|Alphaproteobacteria,4BPBE@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria C 4Fe-4S dicluster domain glcF GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 - ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001 - - - CCG,Fer4_7 CMS1_k127_5461638_1 1187851.A33M_3144 9.995e-263 824.0 COG2225@1|root,COG2225@2|Bacteria,1MVEV@1224|Proteobacteria 1224|Proteobacteria C Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA aceB GO:0003674,GO:0003824,GO:0004474,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006081,GO:0006082,GO:0006097,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044424,GO:0044464,GO:0046487,GO:0046912,GO:0071704 2.3.3.9 ko:K01638 ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200 M00012 R00472 RC00004,RC00308,RC02747 ko00000,ko00001,ko00002,ko01000 - - iEC55989_1330.EC55989_4499,iLF82_1304.LF82_0013,iNRG857_1313.NRG857_20010 Malate_synthase CMS1_k127_5461638_5 1336208.JADY01000015_gene1353 8.153e-153 492.0 COG0473@1|root,COG0473@2|Bacteria,1QU2H@1224|Proteobacteria,2VFXG@28211|Alphaproteobacteria 28211|Alphaproteobacteria CE Dehydrogenase - GO:0006082,GO:0006575,GO:0006732,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016053,GO:0019297,GO:0019298,GO:0019752,GO:0032787,GO:0042398,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576 1.1.1.42,1.1.1.83,1.1.1.85,1.1.1.93,4.1.1.73 ko:K00031,ko:K00052,ko:K07246 ko00020,ko00290,ko00480,ko00630,ko00650,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00290,map00480,map00630,map00650,map00660,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00432,M00535,M00740 R00215,R00267,R00268,R00994,R01751,R01899,R02545,R04426,R06180,R10052 RC00001,RC00084,RC00105,RC00114,RC00417,RC00594,RC00626,RC02801,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh CMS1_k127_5461638_12 388051.AUFE01000058_gene5875 9.527e-31 121.0 COG1028@1|root,COG1028@2|Bacteria,1MUFX@1224|Proteobacteria,2VP08@28216|Betaproteobacteria,1K55P@119060|Burkholderiaceae 28216|Betaproteobacteria IQ Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short_C2 CMS1_k127_5461638_3 504832.OCAR_5303 6.744e-176 556.0 COG1893@1|root,COG1893@2|Bacteria,1QMH8@1224|Proteobacteria,2TSGW@28211|Alphaproteobacteria,3JWCH@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - - - - - - - - - - - CMS1_k127_5461638_13 1187851.A33M_3143 2.273e-13 76.0 2DQY9@1|root,339CR@2|Bacteria,1NR8Y@1224|Proteobacteria,2U152@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Bacterial protein of unknown function (Gcw_chp) - - - - - - - - - - - - Gcw_chp CMS1_k127_5463549_7 589924.Ferp_1437 7.511e-08 62.0 COG5557@1|root,arCOG02025@2157|Archaea,2XWFI@28890|Euryarchaeota,246T1@183980|Archaeoglobi 183980|Archaeoglobi C PFAM Polysulphide reductase, NrfD - - - ko:K00185 - - - - ko00000 5.A.3 - - NrfD CMS1_k127_5463549_2 1379698.RBG1_1C00001G0296 1.561e-68 243.0 COG0437@1|root,COG0437@2|Bacteria,2NR78@2323|unclassified Bacteria 2|Bacteria C 4Fe-4S binding domain ttrB - - ko:K08358 ko00920,ko01120,ko02020,map00920,map01120,map02020 - R10150 RC03109 ko00000,ko00001,ko02000 5.A.3.10 - - Fer4_11,Fer4_3,Fer4_7 CMS1_k127_5463549_4 28229.ND2E_2955 1.442e-33 142.0 COG2863@1|root,COG2863@2|Bacteria,1N2NB@1224|Proteobacteria,1RZFP@1236|Gammaproteobacteria,2Q646@267889|Colwelliaceae 1236|Gammaproteobacteria C Cytochrome c cc4 - - - - - - - - - - - Cytochrom_C CMS1_k127_5463549_6 1379698.RBG1_1C00001G0295 1.213e-19 100.0 COG3303@1|root,COG3303@2|Bacteria 2|Bacteria C Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - ko:K04013,ko:K15876 ko00910,ko01120,map00910,map01120 M00530 R05712 RC00176 ko00000,ko00001,ko00002 - - - Cytochrom_C552,Cytochrom_c3_2,Cytochrome_C554,Paired_CXXCH_1 CMS1_k127_5463549_1 864051.BurJ1DRAFT_0792 5.026e-149 504.0 COG3303@1|root,COG3303@2|Bacteria,1R8WP@1224|Proteobacteria,2VZZU@28216|Betaproteobacteria 28216|Betaproteobacteria C Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - - - - - - - - - - - CMS1_k127_5463549_5 322710.Avin_22870 4.096e-23 109.0 2CEXV@1|root,32S0S@2|Bacteria 2|Bacteria S Type II secretion system protein B gspB - - ko:K02451 - M00331 - - ko00000,ko00002,ko02044 9.B.42 - - T2SSB CMS1_k127_5463549_0 1163617.SCD_n02200 6.768e-226 713.0 COG3267@1|root,COG3409@1|root,COG3267@2|Bacteria,COG3409@2|Bacteria,1MU3G@1224|Proteobacteria,2VIK1@28216|Betaproteobacteria 28216|Betaproteobacteria U SMART AAA ATPase exeA - - ko:K02450 - M00331 - - ko00000,ko00002,ko02044 9.B.42 - - AAA_22,PG_binding_1 CMS1_k127_5463549_3 1535422.ND16A_0736 3.082e-53 203.0 COG3303@1|root,COG3303@2|Bacteria,1R8WP@1224|Proteobacteria 1224|Proteobacteria C Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - - - - - - - - - - Cytochrome_C7 CMS1_k127_5472829_10 441620.Mpop_3412 1.706e-37 143.0 COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,2TSR7@28211|Alphaproteobacteria,1JU0N@119045|Methylobacteriaceae 28211|Alphaproteobacteria M Provides the (R)-glutamate required for cell wall biosynthesis murI - 5.1.1.3 ko:K01776 ko00471,ko01100,map00471,map01100 - R00260 RC00302 ko00000,ko00001,ko01000,ko01011 - - - Asp_Glu_race CMS1_k127_5472829_5 1041159.AZUW01000019_gene73 3.831e-73 253.0 COG0861@1|root,COG0861@2|Bacteria,1PN8B@1224|Proteobacteria,2TUV5@28211|Alphaproteobacteria,4B8F0@82115|Rhizobiaceae 28211|Alphaproteobacteria P membrane protein TerC terC - - - - - - - - - - - TerC CMS1_k127_5472829_3 1187851.A33M_4339 2.286e-107 350.0 COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,2TRQH@28211|Alphaproteobacteria,3FCIF@34008|Rhodovulum 28211|Alphaproteobacteria J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit rpsD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - ko:K02986 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S4,S4 CMS1_k127_5472829_4 420324.KI911947_gene5514 1.64e-85 295.0 COG0491@1|root,COG0491@2|Bacteria,1MY6G@1224|Proteobacteria,2TSXC@28211|Alphaproteobacteria,1JRDB@119045|Methylobacteriaceae 28211|Alphaproteobacteria S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B CMS1_k127_5472829_6 1429916.X566_24105 2.87e-58 206.0 COG0278@1|root,COG0278@2|Bacteria,1MZ4V@1224|Proteobacteria,2U9QB@28211|Alphaproteobacteria,3JYW5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O Belongs to the glutaredoxin family. Monothiol subfamily grlA - - ko:K07390 - - - - ko00000,ko03029,ko03110 - - - Glutaredoxin CMS1_k127_5472829_7 1187851.A33M_0642 1.242e-56 199.0 COG0251@1|root,COG0251@2|Bacteria 2|Bacteria J oxidation-reduction process - - 3.5.99.10 ko:K09022 - - R11098,R11099 RC03275,RC03354 ko00000,ko01000 - - - Ribonuc_L-PSP CMS1_k127_5472829_13 883078.HMPREF9695_02642 2.932e-33 135.0 COG0271@1|root,COG0271@2|Bacteria,1R3MM@1224|Proteobacteria,2UBUW@28211|Alphaproteobacteria,3K02J@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Belongs to the BolA IbaG family MA20_09125 - - - - - - - - - - - BolA CMS1_k127_5472829_9 114615.BRADO5776 1.081e-37 152.0 KOG3648@1|root,32VTC@2|Bacteria,1R6UN@1224|Proteobacteria,2U0NH@28211|Alphaproteobacteria,3JU6D@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S fibroblast growth factor binding - - - - - - - - - - - - Cys_rich_FGFR,GHBP CMS1_k127_5472829_14 1246459.KB898353_gene516 2.322e-05 55.0 KOG3648@1|root,32VTC@2|Bacteria,1R6UN@1224|Proteobacteria,2U0NH@28211|Alphaproteobacteria,4BATH@82115|Rhizobiaceae 28211|Alphaproteobacteria S fibroblast growth factor binding - - - - - - - - - - - - Cys_rich_FGFR,GHBP CMS1_k127_5472829_0 1038859.AXAU01000016_gene6904 0.0 1208.0 COG0046@1|root,COG0046@2|Bacteria,1MYN4@1224|Proteobacteria,2TRGM@28211|Alphaproteobacteria,3JRAU@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purL - 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C CMS1_k127_5472829_2 1380355.JNIJ01000018_gene4517 6.398e-122 399.0 COG0047@1|root,COG0047@2|Bacteria,1MU4Y@1224|Proteobacteria,2TS67@28211|Alphaproteobacteria,3JT4P@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purQ GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - GATase_5 CMS1_k127_5472829_12 1037409.BJ6T_40000 1.892e-34 133.0 COG1828@1|root,COG1828@2|Bacteria,1N83G@1224|Proteobacteria,2UF7S@28211|Alphaproteobacteria,3K02S@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purS - 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - PurS CMS1_k127_5472829_1 693986.MOC_4001 3.807e-159 504.0 COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,2TR8D@28211|Alphaproteobacteria,1JTPH@119045|Methylobacteriaceae 28211|Alphaproteobacteria F PFAM SAICAR synthetase purC - 6.3.2.6 ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04591 RC00064,RC00162 ko00000,ko00001,ko00002,ko01000 - - - SAICAR_synt CMS1_k127_5472829_11 114615.BRADO2775 1.501e-36 141.0 COG5467@1|root,COG5467@2|Bacteria,1MZRN@1224|Proteobacteria,2UC1G@28211|Alphaproteobacteria,3JZI5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Domain of unknown function (DUF1476) MA20_09035 - - - - - - - - - - - DUF1476 CMS1_k127_5472829_8 1411123.JQNH01000001_gene2627 4.743e-56 206.0 COG3836@1|root,COG3836@2|Bacteria,1MUSG@1224|Proteobacteria,2U4E2@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Belongs to the HpcH HpaI aldolase family - - 4.1.2.52 ko:K02510 ko00350,ko01120,map00350,map01120 - R01645,R01647 RC00307,RC00572,RC00574,RC03057 ko00000,ko00001,ko01000 - - - HpcH_HpaI CMS1_k127_5486626_1 1040989.AWZU01000020_gene1996 2.363e-69 256.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,2TQXC@28211|Alphaproteobacteria,3JSB9@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth guaB GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205,1.7.1.7 ko:K00088,ko:K00364 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R01134,R08240 RC00143,RC00457,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 - - - CBS,IMPDH,NMO CMS1_k127_5486626_0 323097.Nham_2548 1.27e-136 442.0 COG0477@1|root,COG2814@2|Bacteria,1MUDA@1224|Proteobacteria,2TS0P@28211|Alphaproteobacteria,3K6NK@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P Major Facilitator Superfamily hsrA GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - - - - - - - - - - MFS_1 CMS1_k127_5491139_0 1197906.CAJQ02000011_gene678 0.0 1270.0 COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,2TSPQ@28211|Alphaproteobacteria,3JSSS@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV CMS1_k127_5491139_4 883080.HMPREF9697_00669 4.478e-70 243.0 COG2095@1|root,COG2095@2|Bacteria,1MX5T@1224|Proteobacteria,2U59A@28211|Alphaproteobacteria,3JS8A@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria U MarC family integral membrane protein marC - - ko:K05595 - - - - ko00000,ko02000 2.A.95.1 - - MarC CMS1_k127_5491139_1 316057.RPD_3027 1.128e-283 878.0 COG3961@1|root,COG3961@2|Bacteria,1MW2F@1224|Proteobacteria,2TRXT@28211|Alphaproteobacteria,3JXPK@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria GH Belongs to the TPP enzyme family ipdC - 4.1.1.1,4.1.1.74 ko:K01568,ko:K04103 ko00010,ko00380,ko01100,ko01110,ko01130,map00010,map00380,map01100,map01110,map01130 - R00014,R00755,R01974 RC00027,RC00375,RC00506,RC02744 ko00000,ko00001,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N CMS1_k127_5491139_3 1187851.A33M_0214 2.194e-76 260.0 COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,2U5BZ@28211|Alphaproteobacteria,3FD5G@34008|Rhodovulum 28211|Alphaproteobacteria L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB CMS1_k127_5491139_5 1038858.AXBA01000016_gene1923 7.463e-44 168.0 COG3637@1|root,COG3637@2|Bacteria,1RKNU@1224|Proteobacteria,2U7U5@28211|Alphaproteobacteria,3EZJK@335928|Xanthobacteraceae 28211|Alphaproteobacteria M PFAM porin - - - ko:K16079 - - - - ko00000,ko02000 1.B.4.2.1 - - OMP_b-brl CMS1_k127_5491139_2 864069.MicloDRAFT_00013940 3.642e-79 269.0 COG1999@1|root,COG1999@2|Bacteria,1MZAW@1224|Proteobacteria,2U1D6@28211|Alphaproteobacteria,1JV5A@119045|Methylobacteriaceae 28211|Alphaproteobacteria S PFAM electron transport protein SCO1 SenC - - - ko:K07152 - - - - ko00000,ko03029 - - - SCO1-SenC CMS1_k127_5497393_11 1187851.A33M_1981 1.036e-54 201.0 COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,2TQJZ@28211|Alphaproteobacteria,3FCUM@34008|Rhodovulum 28211|Alphaproteobacteria L PD-(D/E)XK nuclease superfamily addA - 3.6.4.12 ko:K16898 - - - - ko00000,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C CMS1_k127_5497393_12 1040989.AWZU01000018_gene2720 3.802e-52 186.0 COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,2UCCR@28211|Alphaproteobacteria,3JYUR@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O Belongs to the thioredoxin family trxA - - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin CMS1_k127_5497393_3 1320556.AVBP01000002_gene4102 4.209e-184 585.0 COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,2TR64@28211|Alphaproteobacteria,43IEM@69277|Phyllobacteriaceae 28211|Alphaproteobacteria H Belongs to the folylpolyglutamate synthase family folC - 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - - Mur_ligase_M CMS1_k127_5497393_4 1429916.X566_08500 4.449e-149 475.0 COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,2TRSH@28211|Alphaproteobacteria,3JSZ0@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA accD - 2.1.3.15,6.4.1.2 ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans CMS1_k127_5497393_7 663610.JQKO01000006_gene2650 2.348e-125 406.0 COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,2TQN2@28211|Alphaproteobacteria,3NAJY@45404|Beijerinckiaceae 28211|Alphaproteobacteria E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate trpA - 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - Trp_syntA CMS1_k127_5497393_1 1187851.A33M_1229 2.279e-225 705.0 COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,2TSHK@28211|Alphaproteobacteria,3FCG4@34008|Rhodovulum 28211|Alphaproteobacteria E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine trpB - 4.2.1.20 ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - PALP CMS1_k127_5497393_9 114615.BRADO0092 7.979e-83 286.0 COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,2U7CH@28211|Alphaproteobacteria,3JRQW@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Belongs to the TrpF family trpF - 5.3.1.24 ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03509 RC00945 ko00000,ko00001,ko00002,ko01000 - - - PRAI CMS1_k127_5497393_15 1040989.AWZU01000018_gene2713 6.841e-25 110.0 COG5416@1|root,COG5416@2|Bacteria,1N7CU@1224|Proteobacteria,2UF9B@28211|Alphaproteobacteria,3JYSJ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Lipopolysaccharide assembly protein A domain - - - - - - - - - - - - LapA_dom CMS1_k127_5497393_13 1187851.A33M_1234 8.657e-48 172.0 COG0776@1|root,COG0776@2|Bacteria,1MZ7M@1224|Proteobacteria,2UBR5@28211|Alphaproteobacteria,3FE9Y@34008|Rhodovulum 28211|Alphaproteobacteria K This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control himD GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141 - ko:K05788 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding CMS1_k127_5497393_6 316057.RPD_0193 2.317e-127 414.0 COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,2TSXA@28211|Alphaproteobacteria,3JSKK@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria OU signal peptide peptidase SppA sppA - - ko:K04773 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S49 CMS1_k127_5497393_0 1038860.AXAP01000060_gene2288 7.525e-321 987.0 COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,2TQPV@28211|Alphaproteobacteria,3JUJY@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence rpsA - - ko:K02945 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - S1 CMS1_k127_5497393_8 1429916.X566_08540 3.891e-84 284.0 COG0283@1|root,COG0283@2|Bacteria,1MUUD@1224|Proteobacteria,2U71H@28211|Alphaproteobacteria,3JRP0@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria F Belongs to the cytidylate kinase family. Type 1 subfamily cmk GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 ko:K00945 ko00240,ko01100,map00240,map01100 M00052 R00158,R00512,R01665 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Cytidylate_kin CMS1_k127_5497393_2 1187851.A33M_1241 1.31e-202 639.0 COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,2TR6W@28211|Alphaproteobacteria,3FCQW@34008|Rhodovulum 28211|Alphaproteobacteria E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate aroA GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03460 RC00350 ko00000,ko00001,ko00002,ko01000 - - - EPSP_synthase CMS1_k127_5497393_14 316057.RPD_0188 1.483e-34 139.0 COG4530@1|root,COG4530@2|Bacteria,1N85Z@1224|Proteobacteria,2UF7V@28211|Alphaproteobacteria,3JYU7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (FYDLN_acid) MA20_24185 - - - - - - - - - - - FYDLN_acid CMS1_k127_5497393_5 1231391.AMZF01000010_gene1644 2.446e-143 461.0 COG2159@1|root,COG2159@2|Bacteria,1MXI7@1224|Proteobacteria,2VP80@28216|Betaproteobacteria,3T1KY@506|Alcaligenaceae 28216|Betaproteobacteria S Amidohydrolase - - 4.1.1.103,4.1.1.46 ko:K07045,ko:K14333,ko:K20941 ko00362,ko00627,ko01120,map00362,map00627,map01120 - R00821,R11353 RC00390,RC00569 ko00000,ko00001,ko01000 - - - Amidohydro_2 CMS1_k127_5497393_10 323098.Nwi_2708 8.078e-62 228.0 COG3773@1|root,COG3773@2|Bacteria,1MWX3@1224|Proteobacteria,2TT15@28211|Alphaproteobacteria,3JT5Q@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Cell Wall Hydrolase sleB - - - - - - - - - - - Hydrolase_2 CMS1_k127_5497393_16 1354722.JQLS01000001_gene4808 9.72e-17 80.0 COG4948@1|root,COG4948@2|Bacteria,1MYZE@1224|Proteobacteria,2TU3A@28211|Alphaproteobacteria 28211|Alphaproteobacteria M mandelate racemase muconate lactonizing MA20_06335 - 4.2.1.156,4.2.1.42,5.1.2.2 ko:K01781,ko:K20023 ko00053,ko00627,ko01120,map00053,map00627,map01120 - R03791,R04161,R05608 RC00543,RC00998 ko00000,ko00001,ko01000 - - - MR_MLE_C,MR_MLE_N CMS1_k127_5504612_14 1187851.A33M_1682 3.372e-42 157.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria 28211|Alphaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - CHASE4,EAL,GGDEF,PAS_7 CMS1_k127_5504612_1 1411123.JQNH01000001_gene1087 1.978e-215 673.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TREJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Catalyzes the formation of 3-methylbut-2-enoyl CoA from 3-methylbutanoyl CoA ivd2 - 1.3.8.4 ko:K00253 ko00280,ko01100,map00280,map01100 M00036 R04095 RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N CMS1_k127_5504612_0 1380391.JIAS01000020_gene1697 8.453e-216 675.0 COG5276@1|root,COG5276@2|Bacteria,1MU72@1224|Proteobacteria,2TZVG@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Secreted protein containing C-terminal beta-propeller domain distantly related to WD-40 repeats - - - - - - - - - - - - LVIVD CMS1_k127_5504612_17 1041146.ATZB01000011_gene1012 1.266e-22 107.0 29ZYN@1|root,30N08@2|Bacteria,1RDKN@1224|Proteobacteria,2U7H8@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Eukaryotic cytochrome b561 - - - - - - - - - - - - Cytochrom_B561 CMS1_k127_5504612_16 1429916.X566_22635 1.375e-24 106.0 COG2944@1|root,COG2944@2|Bacteria,1MZGM@1224|Proteobacteria,2UB31@28211|Alphaproteobacteria,3K0GP@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K transcriptional regulator, XRE family - - - ko:K07726 - - - - ko00000,ko03000 - - - HTH_3,HTH_31 CMS1_k127_5504612_8 1131813.AQVT01000001_gene898 4.725e-90 305.0 COG0672@1|root,COG0672@2|Bacteria,1MX1M@1224|Proteobacteria,2TU8Z@28211|Alphaproteobacteria,1JTH5@119045|Methylobacteriaceae 28211|Alphaproteobacteria P Iron permease FTR1 family - - - ko:K07243 - - - - ko00000,ko02000 2.A.108.1,2.A.108.2 - - FTR1 CMS1_k127_5504612_15 743836.AYNA01000041_gene1026 1.411e-28 119.0 COG4633@1|root,COG4633@2|Bacteria,1N6VB@1224|Proteobacteria,2UFK9@28211|Alphaproteobacteria,370PB@31993|Methylocystaceae 28211|Alphaproteobacteria S Cupredoxin-like domain - - - - - - - - - - - - Cupredoxin_1 CMS1_k127_5504612_7 1380355.JNIJ01000028_gene699 1.668e-91 311.0 COG0656@1|root,COG0656@2|Bacteria,1MWFS@1224|Proteobacteria,2TT2Q@28211|Alphaproteobacteria,3JRGG@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Aldo/keto reductase family yafB - - - - - - - - - - - Aldo_ket_red CMS1_k127_5504612_4 1038859.AXAU01000001_gene2719 6.46e-109 359.0 COG0656@1|root,COG0656@2|Bacteria,1MWFS@1224|Proteobacteria,2TT2Q@28211|Alphaproteobacteria,3JRGG@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Aldo/keto reductase family yafB - - - - - - - - - - - Aldo_ket_red CMS1_k127_5504612_11 1225184.ALXE01000038_gene3216 1.733e-77 272.0 COG3391@1|root,COG3391@2|Bacteria,1P0CV@1224|Proteobacteria,1RP6U@1236|Gammaproteobacteria,3W01I@53335|Pantoea 1236|Gammaproteobacteria S WD40 repeats - - - - - - - - - - - - - CMS1_k127_5504612_5 460265.Mnod_1888 4.038e-101 334.0 COG0684@1|root,COG0684@2|Bacteria,1MUWV@1224|Proteobacteria,2TU1X@28211|Alphaproteobacteria,1JQS1@119045|Methylobacteriaceae 28211|Alphaproteobacteria H Aldolase/RraA - - - - - - - - - - - - RraA-like CMS1_k127_5504612_9 443598.AUFA01000003_gene1981 2.588e-86 296.0 COG1434@1|root,COG1434@2|Bacteria,1MVW8@1224|Proteobacteria,2U6XK@28211|Alphaproteobacteria,3JVS4@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S DUF218 domain - - - - - - - - - - - - DUF218 CMS1_k127_5504612_12 1411123.JQNH01000001_gene878 1.891e-65 227.0 COG0607@1|root,COG0607@2|Bacteria,1RHQZ@1224|Proteobacteria,2U9DZ@28211|Alphaproteobacteria 28211|Alphaproteobacteria P rhodanese-related sulfurtransferase MA20_01310 - - - - - - - - - - - Rhodanese CMS1_k127_5504612_6 1187851.A33M_0509 2.331e-93 310.0 COG0625@1|root,COG0625@2|Bacteria,1PHM1@1224|Proteobacteria,2TTQZ@28211|Alphaproteobacteria,3FD8G@34008|Rhodovulum 28211|Alphaproteobacteria O Glutathione S-transferase, N-terminal domain gstch10 - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C_2,GST_N_3 CMS1_k127_5504612_2 1040989.AWZU01000002_gene5427 3.75e-150 484.0 COG1470@1|root,COG1470@2|Bacteria,1R8IF@1224|Proteobacteria,2U1RT@28211|Alphaproteobacteria,3JWD3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S NPCBM-associated, NEW3 domain of alpha-galactosidase - - - - - - - - - - - - NPCBM_assoc CMS1_k127_5504612_10 1353531.AZNX01000005_gene3278 8.79e-82 285.0 COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,2TSI2@28211|Alphaproteobacteria,4B9UK@82115|Rhizobiaceae 28211|Alphaproteobacteria V AAA domain, putative AbiEii toxin, Type IV TA system nosF - - ko:K01990,ko:K19340 ko02010,map02010 M00254,M00762 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.132.2 - - ABC_tran CMS1_k127_5504612_3 94624.Bpet0290 9.021e-127 417.0 COG1277@1|root,COG1277@2|Bacteria,1R5P4@1224|Proteobacteria,2WAGJ@28216|Betaproteobacteria,3T5PG@506|Alcaligenaceae 28216|Betaproteobacteria S ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2 CMS1_k127_5504612_13 1380391.JIAS01000013_gene3772 5.796e-53 190.0 COG4119@1|root,COG4119@2|Bacteria,1RHCE@1224|Proteobacteria,2U8N1@28211|Alphaproteobacteria,2JWUA@204441|Rhodospirillales 204441|Rhodospirillales L NUDIX domain - - - - - - - - - - - - NUDIX CMS1_k127_5504612_20 794903.OPIT5_08080 0.000308 49.0 COG1917@1|root,COG1917@2|Bacteria,46XSB@74201|Verrucomicrobia,3K9M8@414999|Opitutae 414999|Opitutae S Cupin domain - - - - - - - - - - - - Cupin_2 CMS1_k127_5504612_19 1408419.JHYG01000007_gene3043 2.232e-12 69.0 COG3237@1|root,COG3237@2|Bacteria,1NGW6@1224|Proteobacteria,2UJAV@28211|Alphaproteobacteria,2JUSR@204441|Rhodospirillales 204441|Rhodospirillales S Belongs to the UPF0337 (CsbD) family - - - - - - - - - - - - CsbD CMS1_k127_5504612_18 288000.BBta_4213 1.796e-22 102.0 COG3064@1|root,COG3064@2|Bacteria,1MXS9@1224|Proteobacteria,2TV4F@28211|Alphaproteobacteria,3JXNR@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Protein of unknown function (DUF1236) - - - - - - - - - - - - DUF1236 CMS1_k127_5510128_3 316057.RPD_2625 2.976e-63 224.0 COG4166@1|root,COG4166@2|Bacteria,1MUVU@1224|Proteobacteria,2TQJX@28211|Alphaproteobacteria,3JT9M@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Bacterial extracellular solute-binding proteins, family 5 Middle nikA - - ko:K02035,ko:K13893 ko02010,ko02024,map02010,map02024 M00239,M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.21,3.A.1.5.24 - - SBP_bac_5 CMS1_k127_5510128_2 1429916.X566_20810 2.138e-69 250.0 COG5342@1|root,COG5342@2|Bacteria,1MV8Y@1224|Proteobacteria,2TS6A@28211|Alphaproteobacteria,3JRJC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Invasion associated locus B MA20_13025 - - - - - - - - - - - IalB CMS1_k127_5510128_4 1187851.A33M_2862 4.374e-50 182.0 COG3785@1|root,COG3785@2|Bacteria,1RHM7@1224|Proteobacteria,2U9MS@28211|Alphaproteobacteria,3FDDQ@34008|Rhodovulum 28211|Alphaproteobacteria S Hemimethylated DNA-binding protein YccV like hspQ - - ko:K11940 - - - - ko00000,ko03036 - - - YccV-like CMS1_k127_5510128_0 1038858.AXBA01000035_gene305 1.173e-192 606.0 COG2301@1|root,COG2301@2|Bacteria,1MW0A@1224|Proteobacteria,2TU4H@28211|Alphaproteobacteria,3F082@335928|Xanthobacteraceae 28211|Alphaproteobacteria G HpcH/HpaI aldolase/citrate lyase family mcl1 GO:0003674,GO:0003824,GO:0005488,GO:0016829,GO:0016830,GO:0016833,GO:0043167,GO:0043169,GO:0046872,GO:0047777,GO:0050083 4.1.3.24,4.1.3.25 ko:K08691 ko00630,ko00660,ko00680,ko00720,ko01120,ko01200,map00630,map00660,map00680,map00720,map01120,map01200 M00346,M00373,M00376 R00237,R00473,R00934 RC00307,RC00308,RC00311,RC00407,RC00502,RC01205 ko00000,ko00001,ko00002,ko01000 - - - HpcH_HpaI CMS1_k127_5510128_1 1187851.A33M_2859 4.926e-135 441.0 COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,2TT9M@28211|Alphaproteobacteria,3FD2H@34008|Rhodovulum 28211|Alphaproteobacteria CH FAD binding domain ubiH - - ko:K03185 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04989,R08773 RC02670 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 CMS1_k127_5510128_5 666684.AfiDRAFT_2247 0.0005997 43.0 COG1183@1|root,COG1183@2|Bacteria,1NGCJ@1224|Proteobacteria,2TS1K@28211|Alphaproteobacteria,3JTX5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP pcs GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050520,GO:0071704,GO:0090407,GO:1901576 2.7.8.24 ko:K01004 ko00564,ko01110,map00564,map01110 - R05794 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf CMS1_k127_5513837_6 1502724.FF80_00656 3.772e-68 235.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2UQ7P@28211|Alphaproteobacteria,3N840@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria I Thiolase, C-terminal domain - - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N CMS1_k127_5513837_1 316055.RPE_3802 3.109e-218 698.0 COG0318@1|root,COG0318@2|Bacteria,1MUQZ@1224|Proteobacteria,2TRV7@28211|Alphaproteobacteria,3JSE9@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria IQ AMP-binding enzyme MA20_18710 - 6.2.1.34 ko:K12508 - - - - ko00000,ko01000 - - - AMP-binding CMS1_k127_5513837_0 1121033.AUCF01000016_gene5480 1.025e-219 697.0 COG0318@1|root,COG0318@2|Bacteria,1MUQZ@1224|Proteobacteria,2TRV7@28211|Alphaproteobacteria,2JPYI@204441|Rhodospirillales 204441|Rhodospirillales IQ AMP-binding enzyme - - 6.2.1.34 ko:K12508 - - - - ko00000,ko01000 - - - AMP-binding CMS1_k127_5513837_5 1121033.AUCF01000016_gene5479 1.006e-104 346.0 COG1024@1|root,COG1024@2|Bacteria,1MWYZ@1224|Proteobacteria,2TRNB@28211|Alphaproteobacteria,2JWAG@204441|Rhodospirillales 204441|Rhodospirillales I Enoyl-CoA hydratase/isomerase - - - - - - - - - - - - ECH_1 CMS1_k127_5513837_8 479432.Sros_6173 3.03e-43 164.0 2DMP1@1|root,32SS8@2|Bacteria,2INWH@201174|Actinobacteria,4EM19@85012|Streptosporangiales 201174|Actinobacteria S Protein of unknown function (DUF3237) - - - - - - - - - - - - DUF3237 CMS1_k127_5513837_3 1411123.JQNH01000001_gene1937 1.956e-136 439.0 COG1788@1|root,COG1788@2|Bacteria,1NGS5@1224|Proteobacteria,2TVMU@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit catI - 2.8.3.12 ko:K01039 ko00643,ko00650,ko01120,map00643,map00650,map01120 - R04000,R05509 RC00012,RC00131,RC00137 ko00000,ko00001,ko01000 - - - CoA_trans CMS1_k127_5513837_4 1411123.JQNH01000001_gene1936 7.013e-128 412.0 COG2057@1|root,COG2057@2|Bacteria,1MY3S@1224|Proteobacteria,2TUZ8@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Acyl CoA acetate 3-ketoacid CoA transferase beta subunit catJ - 2.8.3.12 ko:K01040 ko00643,ko00650,ko01120,map00643,map00650,map01120 - R04000,R05509 RC00012,RC00131,RC00137 ko00000,ko00001,ko01000 - - - CoA_trans CMS1_k127_5513837_2 1297863.APJF01000021_gene32 7.26e-191 603.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2TQQ7@28211|Alphaproteobacteria,3JSVS@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Belongs to the thiolase family pcaF - 2.3.1.174 ko:K07823 ko00362,ko01120,map00362,map01120 - R00829 RC00004,RC00326 ko00000,ko00001,ko01000 - - - Thiolase_C,Thiolase_N CMS1_k127_5513837_7 1116375.VEJY3_18106 5.515e-45 165.0 COG3618@1|root,COG3618@2|Bacteria,1N2QM@1224|Proteobacteria,1RQ8V@1236|Gammaproteobacteria,1XX15@135623|Vibrionales 135623|Vibrionales S Amidohydrolase - - 3.1.1.57 ko:K10221 ko00362,ko00627,ko01120,map00362,map00627,map01120 - R04277 RC03110 ko00000,ko00001,ko01000 - - - Amidohydro_2 CMS1_k127_5515964_3 1187851.A33M_2380 2.152e-94 311.0 COG0090@1|root,COG0090@2|Bacteria,1MVTD@1224|Proteobacteria,2TTKD@28211|Alphaproteobacteria,3FCQH@34008|Rhodovulum 28211|Alphaproteobacteria J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity rplB GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02886 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L2,Ribosomal_L2_C CMS1_k127_5515964_12 1211115.ALIQ01000213_gene2546 1.026e-48 177.0 COG0185@1|root,COG0185@2|Bacteria,1RGYX@1224|Proteobacteria,2U95S@28211|Alphaproteobacteria,3NBB8@45404|Beijerinckiaceae 28211|Alphaproteobacteria J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA rpsS GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - ko:K02965 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S19 CMS1_k127_5515964_10 1187851.A33M_2378 3.182e-59 207.0 COG0091@1|root,COG0091@2|Bacteria,1RH0W@1224|Proteobacteria,2U96X@28211|Alphaproteobacteria,3FD5N@34008|Rhodovulum 28211|Alphaproteobacteria J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome rplV GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02890 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L22 CMS1_k127_5515964_1 1298867.AUES01000002_gene1554 6.227e-131 428.0 COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,2TRZ2@28211|Alphaproteobacteria,3JVAT@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation rpsC GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02982 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KH_2,Ribosomal_S3_C CMS1_k127_5515964_7 1429916.X566_23000 2.935e-70 239.0 COG0197@1|root,COG0197@2|Bacteria,1RA0Z@1224|Proteobacteria,2U710@28211|Alphaproteobacteria,3JY98@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs rplP GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - ko:K02878 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L16 CMS1_k127_5515964_17 1101190.ARWB01000001_gene780 6.128e-21 96.0 COG0255@1|root,COG0255@2|Bacteria,1N6PR@1224|Proteobacteria,2UF59@28211|Alphaproteobacteria,36YS5@31993|Methylocystaceae 28211|Alphaproteobacteria J Ribosomal L29 protein rpmC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02904 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L29 CMS1_k127_5515964_15 1187851.A33M_2374 5.557e-38 143.0 COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,2UBRF@28211|Alphaproteobacteria,3FDBX@34008|Rhodovulum 28211|Alphaproteobacteria J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA rpsQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02961 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S17 CMS1_k127_5515964_9 1040989.AWZU01000014_gene4531 9.946e-65 226.0 COG0093@1|root,COG0093@2|Bacteria,1RCWZ@1224|Proteobacteria,2U743@28211|Alphaproteobacteria,3JYBD@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome rplN GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - ko:K02874 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L14 CMS1_k127_5515964_13 1187851.A33M_2372 8.701e-46 173.0 COG0198@1|root,COG0198@2|Bacteria,1MZQD@1224|Proteobacteria,2UC6Y@28211|Alphaproteobacteria,3FDD8@34008|Rhodovulum 28211|Alphaproteobacteria J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit rplX GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02895 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KOW,ribosomal_L24 CMS1_k127_5515964_4 1429916.X566_22975 2.499e-84 288.0 COG0094@1|root,COG0094@2|Bacteria,1MUU9@1224|Proteobacteria,2TQPF@28211|Alphaproteobacteria,3JTZ9@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits rplE GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02931 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L5,Ribosomal_L5_C CMS1_k127_5515964_14 1429916.X566_22970 4.491e-43 161.0 COG0199@1|root,COG0199@2|Bacteria,1MZDT@1224|Proteobacteria,2UC01@28211|Alphaproteobacteria,3JZGR@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site rpsN GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02954 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S14 CMS1_k127_5515964_8 189753.AXAS01000002_gene5110 2.501e-65 225.0 COG0096@1|root,COG0096@2|Bacteria,1RDG3@1224|Proteobacteria,2U6ZH@28211|Alphaproteobacteria,3JY5V@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit rpsH GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02994 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S8 CMS1_k127_5515964_5 1187851.A33M_2368 2.939e-80 271.0 COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,2TV09@28211|Alphaproteobacteria,3FD00@34008|Rhodovulum 28211|Alphaproteobacteria J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center rplF GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02933 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L6 CMS1_k127_5515964_16 911045.PSE_3863 2.352e-37 144.0 COG0256@1|root,COG0256@2|Bacteria,1RGY7@1224|Proteobacteria,2U9A6@28211|Alphaproteobacteria 28211|Alphaproteobacteria J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance rplR GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - ko:K02881 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L18p CMS1_k127_5515964_2 1187851.A33M_2366 8.747e-98 322.0 COG0098@1|root,COG0098@2|Bacteria,1MUS4@1224|Proteobacteria,2TSRI@28211|Alphaproteobacteria,3FCX8@34008|Rhodovulum 28211|Alphaproteobacteria J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body rpsE GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02988 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S5,Ribosomal_S5_C CMS1_k127_5515964_18 911045.PSE_3861 6.76e-20 93.0 COG1841@1|root,COG1841@2|Bacteria,1PU2S@1224|Proteobacteria,2UF55@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Ribosomal protein L30 rpmD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02907 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L30 CMS1_k127_5515964_11 1187851.A33M_2364 4.321e-58 207.0 COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,2U79D@28211|Alphaproteobacteria,3FDAZ@34008|Rhodovulum 28211|Alphaproteobacteria J binds to the 23S rRNA rplO GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02876 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27A CMS1_k127_5515964_0 1187851.A33M_2363 7.312e-254 787.0 COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,2TQMT@28211|Alphaproteobacteria,3FCNY@34008|Rhodovulum 28211|Alphaproteobacteria U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently secY - - ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5 - - SecY CMS1_k127_5515964_6 1187851.A33M_2362 1.411e-75 264.0 COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,2TT6A@28211|Alphaproteobacteria,3FD55@34008|Rhodovulum 28211|Alphaproteobacteria F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism adk - 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ADK,ADK_lid CMS1_k127_5515964_19 438753.AZC_2532 2.141e-08 57.0 COG0099@1|root,COG0099@2|Bacteria,1RD1G@1224|Proteobacteria,2U73D@28211|Alphaproteobacteria,3EZI4@335928|Xanthobacteraceae 28211|Alphaproteobacteria J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits rpsM GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02952 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S13 CMS1_k127_5522050_1 1453501.JELR01000002_gene568 7.801e-07 61.0 COG2199@1|root,COG3706@2|Bacteria,1MWHH@1224|Proteobacteria,1RRU7@1236|Gammaproteobacteria,465TD@72275|Alteromonadaceae 1236|Gammaproteobacteria T 7TMR-DISM extracellular 2 - - - - - - - - - - - - 7TMR-DISMED2,7TMR-DISM_7TM,GGDEF CMS1_k127_5522050_0 582744.Msip34_0624 8.285e-96 319.0 COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,2VIWS@28216|Betaproteobacteria,2KKV0@206350|Nitrosomonadales 206350|Nitrosomonadales NU PFAM type II secretion system protein E - - - ko:K02670 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSE CMS1_k127_5523230_1 1040989.AWZU01000003_gene6776 8.289e-120 388.0 COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,2TRXE@28211|Alphaproteobacteria,3JQQ3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Belongs to the universal ribosomal protein uS2 family rpsB GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02967 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S2 CMS1_k127_5523230_0 1187851.A33M_2111 1.439e-148 475.0 COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,2TQM0@28211|Alphaproteobacteria,3FCXS@34008|Rhodovulum 28211|Alphaproteobacteria J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome tsf GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02357 - - - - ko00000,ko03012,ko03029 - - - EF_TS CMS1_k127_5523230_3 1380355.JNIJ01000025_gene1226 8.944e-99 327.0 COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,2TQYN@28211|Alphaproteobacteria,3JQN8@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria F Catalyzes the reversible phosphorylation of UMP to UDP pyrH - 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 - R00158 RC00002 ko00000,ko00001,ko01000 - - - AA_kinase CMS1_k127_5523230_4 1040989.AWZU01000003_gene6779 1.542e-85 287.0 COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,2U5B2@28211|Alphaproteobacteria,3JT3Y@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another frr GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - ko:K02838 - - - - ko00000,ko03012 - - - RRF CMS1_k127_5523230_2 504832.OCAR_5959 3.862e-114 373.0 COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,2TTVJ@28211|Alphaproteobacteria,3JTBS@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids uppS GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 - R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 - - - Prenyltransf CMS1_k127_5523230_5 1187851.A33M_2115 1.723e-67 243.0 COG0575@1|root,COG0575@2|Bacteria,1MWSV@1224|Proteobacteria,2U9ED@28211|Alphaproteobacteria,3FDEV@34008|Rhodovulum 28211|Alphaproteobacteria I Cytidylyltransferase family cdsA - 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_1 CMS1_k127_5523230_6 666684.AfiDRAFT_3315 1.695e-35 139.0 COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,2TSD1@28211|Alphaproteobacteria,3JRCU@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) dxr GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05688 RC01452 ko00000,ko00001,ko00002,ko01000 - - - DXPR_C,DXP_redisom_C,DXP_reductoisom CMS1_k127_5533415_4 935840.JAEQ01000015_gene3702 2.395e-06 57.0 COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,2TQQ8@28211|Alphaproteobacteria,43H7J@69277|Phyllobacteriaceae 28211|Alphaproteobacteria M penicillin-binding protein mrcB - 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - BA14K,Transgly,Transpeptidase CMS1_k127_5533415_5 716928.AJQT01000015_gene4832 1.895e-05 55.0 COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,2TQQ8@28211|Alphaproteobacteria,4BCII@82115|Rhizobiaceae 28211|Alphaproteobacteria M penicillin-binding protein mrcB - 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - BA14K,Transgly,Transpeptidase CMS1_k127_5533415_3 211165.AJLN01000047_gene6145 5.344e-27 113.0 COG0797@1|root,COG0797@2|Bacteria,1G0XF@1117|Cyanobacteria,1JH60@1189|Stigonemataceae 1117|Cyanobacteria M Lytic transglycolase rlpA - - ko:K03642 - - - - ko00000 - - - DPBB_1 CMS1_k127_5533415_1 1231391.AMZF01000010_gene1689 3.21e-217 687.0 COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,2VI6D@28216|Betaproteobacteria,3T3B6@506|Alcaligenaceae 28216|Betaproteobacteria C Fumarate reductase flavoprotein C-term - - 1.3.5.1,1.3.5.4 ko:K00239,ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134 M00009,M00011,M00149,M00150,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C CMS1_k127_5533415_2 1207063.P24_11557 1.27e-41 159.0 COG0479@1|root,COG0479@2|Bacteria,1N210@1224|Proteobacteria,2UDMB@28211|Alphaproteobacteria,2JX7K@204441|Rhodospirillales 204441|Rhodospirillales C 2Fe-2S iron-sulfur cluster binding domain - - - - - - - - - - - - Fer2_3 CMS1_k127_5533415_0 1046724.KB889897_gene3376 1.827e-239 757.0 COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,1RMH7@1236|Gammaproteobacteria,465DR@72275|Alteromonadaceae 1236|Gammaproteobacteria S transport system, fused permease components - - - - - - - - - - - - DctM CMS1_k127_5546187_1 1120792.JAFV01000001_gene1162 2.03e-108 353.0 COG0223@1|root,COG0223@2|Bacteria,1MW07@1224|Proteobacteria,2U0GD@28211|Alphaproteobacteria,371CA@31993|Methylocystaceae 28211|Alphaproteobacteria J Formyl transferase, C-terminal domain - - 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 - R03940 RC00026,RC00165 ko00000,ko00001,ko01000 - - - Formyl_trans_C,Formyl_trans_N CMS1_k127_5546187_0 595536.ADVE02000001_gene2292 1.51e-205 644.0 COG2759@1|root,COG2759@2|Bacteria,1MUR8@1224|Proteobacteria,2TRMM@28211|Alphaproteobacteria,36XKU@31993|Methylocystaceae 28211|Alphaproteobacteria F Formate--tetrahydrofolate ligase fhs - 6.3.4.3 ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R00943 RC00026,RC00111 ko00000,ko00001,ko00002,ko01000 - - - FTHFS CMS1_k127_5546336_0 1123229.AUBC01000010_gene3298 9.603e-282 874.0 COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,2TRA0@28211|Alphaproteobacteria,3JRYB@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Carboxyl transferase domain mccB - 6.4.1.4 ko:K01969 ko00280,ko01100,map00280,map01100 M00036 R04138 RC00367,RC00942 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans CMS1_k127_5546336_3 414684.RC1_0766 1.027e-27 117.0 COG3453@1|root,COG3453@2|Bacteria,1N9AF@1224|Proteobacteria,2UG4C@28211|Alphaproteobacteria,2JZD0@204441|Rhodospirillales 204441|Rhodospirillales S Putative phosphatase (DUF442) - - - - - - - - - - - - DUF442 CMS1_k127_5546336_4 716928.AJQT01000077_gene939 2.27e-19 89.0 COG3071@1|root,COG3071@2|Bacteria,1N6Y8@1224|Proteobacteria,2UFTD@28211|Alphaproteobacteria,4BHED@82115|Rhizobiaceae 28211|Alphaproteobacteria H Protein of unknown function (DUF2905) - - - - - - - - - - - - DUF2905 CMS1_k127_5546336_1 1121861.KB899914_gene1952 4.603e-93 312.0 COG1028@1|root,COG1028@2|Bacteria,1MWJQ@1224|Proteobacteria,2TSQ1@28211|Alphaproteobacteria,2JRQ3@204441|Rhodospirillales 204441|Rhodospirillales IQ Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short CMS1_k127_5546336_2 224911.27355266 1.212e-29 124.0 2CP7W@1|root,32SIM@2|Bacteria,1MZAF@1224|Proteobacteria,2UD6E@28211|Alphaproteobacteria,3JZ2A@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_5548985_5 1231185.BAMP01000027_gene2640 1.839e-17 83.0 COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,2TS97@28211|Alphaproteobacteria,43HC7@69277|Phyllobacteriaceae 28211|Alphaproteobacteria C NADH-quinone oxidoreductase nuoG - 1.6.5.3 ko:K00336 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Fer2_4,Molybdopterin,NADH-G_4Fe-4S_3,NADH_dhqG_C CMS1_k127_5548985_0 258594.RPA2943 1.281e-187 590.0 COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,2TS09@28211|Alphaproteobacteria,3JRWX@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone nuoH GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 ko:K00337 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - NADHdh CMS1_k127_5548985_6 1123229.AUBC01000007_gene60 9.228e-16 79.0 2B152@1|root,31TIY@2|Bacteria,1NG85@1224|Proteobacteria,2UGDQ@28211|Alphaproteobacteria,3K5CC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_5548985_2 1131814.JAFO01000001_gene2035 2.547e-99 325.0 COG1143@1|root,COG1143@2|Bacteria,1MV90@1224|Proteobacteria,2TRFE@28211|Alphaproteobacteria,3EY8F@335928|Xanthobacteraceae 28211|Alphaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoI GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3,1.6.99.3 ko:K00338,ko:K03941 ko00190,ko01100,ko04714,ko04723,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04714,map04723,map04932,map05010,map05012,map05016 M00143,M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1,3.D.1.6 - - Fer4 CMS1_k127_5548985_3 504832.OCAR_5932 7.132e-84 286.0 COG0839@1|root,COG0839@2|Bacteria,1MWJV@1224|Proteobacteria,2TRB2@28211|Alphaproteobacteria,3JRMX@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Belongs to the complex I subunit 6 family nuoJ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 ko:K00339 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q3 CMS1_k127_5548985_4 1187851.A33M_2710 9.611e-47 169.0 COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,2U93P@28211|Alphaproteobacteria,3FDAI@34008|Rhodovulum 28211|Alphaproteobacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoK GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 ko:K00340 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q2 CMS1_k127_5548985_1 316058.RPB_2585 2.193e-174 560.0 COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,2TQSS@28211|Alphaproteobacteria,3JSBH@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria CP NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus nuoL - 1.6.5.3 ko:K00341 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - NADH5_C,Proton_antipo_M,Proton_antipo_N CMS1_k127_5556580_2 1304883.KI912532_gene1258 1.073e-61 219.0 COG3876@1|root,COG3876@2|Bacteria,1MX3S@1224|Proteobacteria,2VMMF@28216|Betaproteobacteria,2KV9B@206389|Rhodocyclales 206389|Rhodocyclales S Protein of unknown function (DUF1343) - - - - - - - - - - - - DUF1343 CMS1_k127_5556580_3 1123269.NX02_16505 1.03e-40 156.0 2DPQ0@1|root,332XN@2|Bacteria,1R3DX@1224|Proteobacteria,2UHFZ@28211|Alphaproteobacteria,2KEWP@204457|Sphingomonadales 204457|Sphingomonadales - - - - - - - - - - - - - - - CMS1_k127_5556580_0 1469245.JFBG01000016_gene989 0.0 1062.0 COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,1RN40@1236|Gammaproteobacteria,1X2WW@135613|Chromatiales 1236|Gammaproteobacteria C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain yagR GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016903,GO:0030151,GO:0033554,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114 1.17.1.4 ko:K11177 ko00230,ko01100,ko01120,map00230,map01100,map01120 M00546 R01768,R02103 RC00143 ko00000,ko00001,ko00002,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 CMS1_k127_5556580_1 331869.BAL199_28605 3.154e-84 289.0 COG1319@1|root,COG1319@2|Bacteria,1RCRH@1224|Proteobacteria,2TU08@28211|Alphaproteobacteria 28211|Alphaproteobacteria C COG1319 Aerobic-type carbon monoxide dehydrogenase middle subunit CoxM CutM homologs xdhB - 1.2.5.3 ko:K03519 - - R11168 RC02800 ko00000,ko01000 - - - CO_deh_flav_C,FAD_binding_5 CMS1_k127_5574177_0 1429916.X566_14095 4.521e-264 827.0 COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,2TRU2@28211|Alphaproteobacteria,3JQWZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB_bind,Toprim_4,Toprim_N,zf-CHC2 CMS1_k127_5574177_1 1304878.AUGD01000008_gene6069 3.041e-229 721.0 COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,2TS6C@28211|Alphaproteobacteria,3JSBI@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth rpoD - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 CMS1_k127_5576302_4 709797.CSIRO_1310 1.864e-90 300.0 COG3572@1|root,COG3572@2|Bacteria,1MU47@1224|Proteobacteria,2TRPT@28211|Alphaproteobacteria,3JR2Q@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H glutamate--cysteine ligase gshA - 6.3.2.2 ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 M00118 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - GCS2 CMS1_k127_5576302_3 1297863.APJF01000010_gene3117 5.709e-93 312.0 COG0580@1|root,COG0580@2|Bacteria,1PPTN@1224|Proteobacteria,2TW8M@28211|Alphaproteobacteria,3JRC9@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G Belongs to the MIP aquaporin (TC 1.A.8) family aqpZ - - - - - - - - - - - MIP CMS1_k127_5576302_6 1297863.APJF01000010_gene3118 7.189e-71 243.0 COG0394@1|root,COG0394@2|Bacteria,1MWYQ@1224|Proteobacteria,2TU1U@28211|Alphaproteobacteria,3JT8H@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Low molecular weight phosphotyrosine protein phosphatase - - 1.20.4.1 ko:K03741 - - - - ko00000,ko01000 - - - HTH_20,LMWPc CMS1_k127_5576302_8 221988.MS1052 4.205e-43 166.0 COG2999@1|root,COG2999@2|Bacteria,1N9FA@1224|Proteobacteria,1RMFC@1236|Gammaproteobacteria,1Y81S@135625|Pasteurellales 135625|Pasteurellales O Glutaredoxin Z012_04495 - - ko:K03675 - - - - ko00000,ko03110 - - - GST_N_3,Glutaredoxin2_C CMS1_k127_5576302_5 1038866.KB902796_gene7410 4.52e-73 248.0 COG0346@1|root,COG0346@2|Bacteria,1RHIV@1224|Proteobacteria,2TR4K@28211|Alphaproteobacteria,3JY40@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E glyoxalase bleomycin resistance protein dioxygenase - - - - - - - - - - - - Glyoxalase CMS1_k127_5576302_7 1038866.KB902796_gene7409 1.092e-43 161.0 COG0640@1|root,COG0640@2|Bacteria,1MZAU@1224|Proteobacteria,2U9NV@28211|Alphaproteobacteria,3JZQ9@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K helix_turn_helix, Arsenical Resistance Operon Repressor - - - ko:K03892 - - - - ko00000,ko03000 - - - HTH_20 CMS1_k127_5576302_1 288000.BBta_1859 3.308e-192 605.0 COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,2TQWC@28211|Alphaproteobacteria,3JSER@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L UvrD-like helicase C-terminal domain recD - 3.1.11.5 ko:K01144 - - - - ko00000,ko01000 - - - AAA_30,UvrD_C_2 CMS1_k127_5576302_9 1331060.RLDS_08135 9.565e-33 130.0 COG2827@1|root,COG2827@2|Bacteria,1MZME@1224|Proteobacteria,2UCNX@28211|Alphaproteobacteria,2K5XX@204457|Sphingomonadales 204457|Sphingomonadales L endonuclease containing a URI domain - - - ko:K07461 - - - - ko00000 - - - GIY-YIG CMS1_k127_5576302_2 1038859.AXAU01000001_gene3420 1.562e-155 500.0 COG0477@1|root,COG2814@2|Bacteria,1MXPM@1224|Proteobacteria,2TSB9@28211|Alphaproteobacteria,3K6SH@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria EGP Sugar (and other) transporter - - - - - - - - - - - - MFS_1,Sugar_tr CMS1_k127_5576302_0 1429916.X566_05970 2.17e-247 773.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2TS8E@28211|Alphaproteobacteria,3JSUZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I enoyl-CoA hydratase isomerase fadJ - 1.1.1.35,4.2.1.17,5.1.2.3 ko:K01782 ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212 M00032,M00087 R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094 RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - - 3HCDH,3HCDH_N,ECH_1 CMS1_k127_5578571_1 196490.AUEZ01000122_gene2580 4.222e-120 399.0 COG2267@1|root,COG2267@2|Bacteria,1NK3M@1224|Proteobacteria,2TRP8@28211|Alphaproteobacteria,3JWKI@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Alpha beta hydrolase MA20_22480 - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 CMS1_k127_5578571_0 1244869.H261_06801 7.38e-204 647.0 COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2TR3P@28211|Alphaproteobacteria,2JRE7@204441|Rhodospirillales 204441|Rhodospirillales I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases - - - - - - - - - - - - AMP-binding,AMP-binding_C CMS1_k127_5578571_2 1033802.SSPSH_001868 6.577e-23 105.0 COG0620@1|root,COG0620@2|Bacteria 2|Bacteria E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_2 CMS1_k127_5587003_0 1205680.CAKO01000002_gene2627 2.689e-162 522.0 COG0111@1|root,COG0111@2|Bacteria,1MW1U@1224|Proteobacteria 1224|Proteobacteria EH D-isomer specific 2-hydroxyacid dehydrogenase - - - - - - - - - - - - 2-Hacid_dh_C CMS1_k127_5587003_1 314345.SPV1_05148 7.357e-51 185.0 COG3791@1|root,COG3791@2|Bacteria 2|Bacteria S Glutathione-dependent formaldehyde-activating - - - - - - - - - - - - GFA CMS1_k127_5587003_2 1125973.JNLC01000010_gene1853 6.32e-45 168.0 COG1917@1|root,COG1917@2|Bacteria,1NQMB@1224|Proteobacteria,2UPJ2@28211|Alphaproteobacteria,3K5KE@41294|Bradyrhizobiaceae 2|Bacteria S Cupin domain - - - - - - - - - - - - AraC_binding,Cupin_2 CMS1_k127_5589388_0 335659.S23_66740 3.027e-207 650.0 COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,2TR7V@28211|Alphaproteobacteria,3JRG1@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L DEAD/H associated lhr - - ko:K03724 - - - - ko00000,ko01000,ko03400 - - - DEAD,DEAD_assoc,Helicase_C CMS1_k127_5589388_4 1120792.JAFV01000001_gene3620 7.043e-81 277.0 COG1407@1|root,COG1407@2|Bacteria,1RC5G@1224|Proteobacteria,2TU2T@28211|Alphaproteobacteria,36Z36@31993|Methylocystaceae 28211|Alphaproteobacteria S Calcineurin-like phosphoesterase MA20_22045 - - ko:K06953 - - - - ko00000 - - - Metallophos CMS1_k127_5589388_3 323097.Nham_0244 4.207e-91 306.0 2AFUA@1|root,315WQ@2|Bacteria,1NHGB@1224|Proteobacteria,2TQWW@28211|Alphaproteobacteria,3JS8S@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Putative transmembrane protein (Alph_Pro_TM) MA20_19830 - - - - - - - - - - - Alph_Pro_TM CMS1_k127_5589388_2 1038859.AXAU01000005_gene5056 3.081e-133 431.0 COG0730@1|root,COG0730@2|Bacteria,1MWX2@1224|Proteobacteria,2TRIC@28211|Alphaproteobacteria,3JTKX@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S membrane transporter protein MA20_19835 - - ko:K07090 - - - - ko00000 - - - TauE CMS1_k127_5589388_1 316055.RPE_0715 7.923e-193 641.0 COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2TR2B@28211|Alphaproteobacteria,3JRS2@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria D Sel1-like repeats. - - - ko:K07126,ko:K13582 ko04112,map04112 - - - ko00000,ko00001 - - - PG_binding_1,Sel1 CMS1_k127_5589388_5 1411123.JQNH01000001_gene3623 3.163e-26 108.0 COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,2TQJS@28211|Alphaproteobacteria 28211|Alphaproteobacteria I acyl-CoA dehydrogenase MA20_19860 - 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N CMS1_k127_5597127_4 311403.Arad_8824 1.122e-71 244.0 COG2141@1|root,COG2141@2|Bacteria,1N899@1224|Proteobacteria,2TTZ7@28211|Alphaproteobacteria,4BBF8@82115|Rhizobiaceae 28211|Alphaproteobacteria C Luciferase-like monooxygenase MA20_21690 - - - - - - - - - - - Bac_luciferase CMS1_k127_5597127_7 1380355.JNIJ01000087_gene4147 1.836e-10 68.0 2EJVC@1|root,33DK2@2|Bacteria,1N9WN@1224|Proteobacteria,2UHCD@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_5597127_5 1037409.BJ6T_87360 2.165e-59 218.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind CMS1_k127_5597127_3 420324.KI912026_gene5005 4.453e-132 426.0 COG1028@1|root,COG1028@2|Bacteria,1MUSQ@1224|Proteobacteria,2TTJC@28211|Alphaproteobacteria,1JRVN@119045|Methylobacteriaceae 28211|Alphaproteobacteria IQ Short-chain dehydrogenase reductase SDR - - - ko:K13775 ko00281,map00281 - R08087,R08096,R10125,R10126 RC00080,RC00087 ko00000,ko00001 - - - adh_short,adh_short_C2 CMS1_k127_5597127_0 391937.NA2_20729 1.729e-162 521.0 COG1804@1|root,COG1804@2|Bacteria,1MU5U@1224|Proteobacteria,2TRIZ@28211|Alphaproteobacteria,43NMH@69277|Phyllobacteriaceae 28211|Alphaproteobacteria C CoA-transferase family III - - - - - - - - - - - - CoA_transf_3 CMS1_k127_5597127_2 981384.AEYW01000001_gene1460 3.805e-133 432.0 COG1638@1|root,COG1638@2|Bacteria,1PJFZ@1224|Proteobacteria,2V8IJ@28211|Alphaproteobacteria,4NDJA@97050|Ruegeria 28211|Alphaproteobacteria G Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP CMS1_k127_5597127_6 981384.AEYW01000001_gene1461 4.769e-37 145.0 COG3090@1|root,COG3090@2|Bacteria,1N7J6@1224|Proteobacteria,2UDKU@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Tripartite ATP-independent periplasmic transporters, DctQ component - - - - - - - - - - - - DctQ CMS1_k127_5597127_1 981384.AEYW01000001_gene1462 1.658e-152 495.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQW5@28211|Alphaproteobacteria 28211|Alphaproteobacteria G COG1593 TRAP-type C4-dicarboxylate transport system large permease component - - - ko:K11690 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.56.1 - - DctM CMS1_k127_5604226_1 994573.T472_0216735 2.986e-06 50.0 COG1593@1|root,COG1593@2|Bacteria,1TPNU@1239|Firmicutes,248BY@186801|Clostridia,36G8D@31979|Clostridiaceae 186801|Clostridia G Trap dicarboxylate transporter, dctm subunit - - - ko:K11690 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.56.1 - - DctM CMS1_k127_5604226_0 1146883.BLASA_1444 1.781e-76 273.0 COG2141@1|root,COG2141@2|Bacteria,2IF10@201174|Actinobacteria,4ESNM@85013|Frankiales 201174|Actinobacteria C Luciferase-like monooxygenase - - - - - - - - - - - - Bac_luciferase CMS1_k127_5631040_0 765912.Thimo_3379 1.78e-96 324.0 COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,1RMMW@1236|Gammaproteobacteria,1WWWV@135613|Chromatiales 135613|Chromatiales M Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) lpxK - 2.7.1.130 ko:K00912 ko00540,ko01100,map00540,map01100 M00060 R04657 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 - - - LpxK CMS1_k127_5631040_3 1218084.BBJK01000078_gene5403 4.085e-16 81.0 COG2835@1|root,COG2835@2|Bacteria,1N6Y2@1224|Proteobacteria,2VW58@28216|Betaproteobacteria,1K96V@119060|Burkholderiaceae 28216|Betaproteobacteria S Belongs to the UPF0434 family ycaR - - ko:K09791 - - - - ko00000 - - - Trm112p CMS1_k127_5631040_1 283942.IL1510 1.889e-87 296.0 COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,1RMAE@1236|Gammaproteobacteria,2QFIN@267893|Idiomarinaceae 1236|Gammaproteobacteria M Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria kdsB GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005996,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008690,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019294,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046394,GO:0046400,GO:0046401,GO:0046872,GO:0070567,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.7.38 ko:K00979 ko00540,ko01100,map00540,map01100 M00063 R03351,R11396 RC00152,RC00910 ko00000,ko00001,ko00002,ko01000,ko01005 - - iAF1260.b0918,iB21_1397.B21_00929,iBWG_1329.BWG_0770,iECBD_1354.ECBD_2677,iECB_1328.ECB_00922,iECDH10B_1368.ECDH10B_0988,iECDH1ME8569_1439.ECDH1ME8569_0869,iECD_1391.ECD_00922,iETEC_1333.ETEC_0986,iEcDH1_1363.EcDH1_2725,iEcHS_1320.EcHS_A1025,iEcolC_1368.EcolC_2678,iJO1366.b0918,iJR904.b0918,iPC815.YPO1400,iUMNK88_1353.UMNK88_1071,iY75_1357.Y75_RS04770 CTP_transf_3 CMS1_k127_5631040_2 768671.ThimaDRAFT_2888 4.573e-62 216.0 COG0394@1|root,COG0394@2|Bacteria,1RH90@1224|Proteobacteria,1S5X6@1236|Gammaproteobacteria,1WY50@135613|Chromatiales 135613|Chromatiales T low molecular weight - - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - LMWPc CMS1_k127_5643952_1 666684.AfiDRAFT_3126 1.279e-87 295.0 COG1063@1|root,COG1063@2|Bacteria,1MV9A@1224|Proteobacteria,2TSWA@28211|Alphaproteobacteria,3JUF7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Alcohol dehydrogenase GroES-like domain - - - - - - - - - - - - ADH_N,ADH_zinc_N CMS1_k127_5643952_2 883080.HMPREF9697_01400 3.962e-74 262.0 COG1414@1|root,COG1414@2|Bacteria,1MUNW@1224|Proteobacteria,2TSY8@28211|Alphaproteobacteria,3JTIU@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K helix_turn_helix isocitrate lyase regulation - - - - - - - - - - - - HTH_IclR,IclR CMS1_k127_5643952_3 1207063.P24_16502 1.835e-65 229.0 COG0279@1|root,COG0279@2|Bacteria,1NVIE@1224|Proteobacteria,2U8QT@28211|Alphaproteobacteria,2JSGE@204441|Rhodospirillales 204441|Rhodospirillales G Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate gmhA - 5.3.1.28 ko:K03271 ko00540,ko01100,map00540,map01100 M00064 R05645,R09768,R09769 RC00434 ko00000,ko00001,ko00002,ko01000,ko01005 - - - SIS_2 CMS1_k127_5643952_5 580332.Slit_0319 2.37e-10 72.0 2ETRW@1|root,33M9C@2|Bacteria,1NEBE@1224|Proteobacteria,2VXIY@28216|Betaproteobacteria,44W11@713636|Nitrosomonadales 28216|Betaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_5643952_4 395494.Galf_0202 9.882e-43 171.0 COG4409@1|root,COG4692@1|root,COG4409@2|Bacteria,COG4692@2|Bacteria,1Q1EG@1224|Proteobacteria,2VMXN@28216|Betaproteobacteria,44VCC@713636|Nitrosomonadales 28216|Betaproteobacteria G BNR repeat-like domain - - - - - - - - - - - - BNR_2 CMS1_k127_5643952_6 59538.XP_005971086.1 0.0001179 51.0 KOG3544@1|root,KOG3544@2759|Eukaryota,38DSM@33154|Opisthokonta,3BEGV@33208|Metazoa,3CX4N@33213|Bilateria,48AY0@7711|Chordata,48UYQ@7742|Vertebrata,3JC5E@40674|Mammalia,4J364@91561|Cetartiodactyla 33208|Metazoa W Collagen alpha-1(XXIII) chain COL23A1 GO:0003674,GO:0005488,GO:0005515,GO:0005539,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005788,GO:0005886,GO:0008150,GO:0008201,GO:0009986,GO:0009987,GO:0012505,GO:0016020,GO:0016043,GO:0022607,GO:0031974,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043933,GO:0044085,GO:0044421,GO:0044422,GO:0044424,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0046983,GO:0051259,GO:0051260,GO:0065003,GO:0070013,GO:0070206,GO:0070207,GO:0071840,GO:0071944,GO:0097367,GO:1901681 - ko:K16617 ko04974,map04974 - - - ko00000,ko00001,ko00536 - - - Collagen CMS1_k127_5643952_0 709797.CSIRO_3871 3.652e-107 350.0 COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,2TT4K@28211|Alphaproteobacteria,3JR9W@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria GM Polysaccharide biosynthesis protein MA20_07945 - - ko:K13013 - - - - ko00000,ko01005 - - - CoA_binding_3,Polysacc_synt_2 CMS1_k127_565310_0 1038860.AXAP01000078_gene1533 2.51e-287 890.0 COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,2TQJS@28211|Alphaproteobacteria,3JUYV@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Acyl-CoA dehydrogenase N terminal MA20_19860 - 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N CMS1_k127_565310_1 1126627.BAWE01000002_gene266 1.712e-109 360.0 COG5473@1|root,COG5473@2|Bacteria,1MVRU@1224|Proteobacteria,2TRUD@28211|Alphaproteobacteria,3JSJI@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Predicted integral membrane protein (DUF2189) MA20_04950 - - - - - - - - - - - DUF2189 CMS1_k127_565310_3 196490.AUEZ01000012_gene4785 6.602e-17 89.0 COG5388@1|root,COG5388@2|Bacteria,1MY02@1224|Proteobacteria,2U114@28211|Alphaproteobacteria,3JWNF@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S PAS domain - - - - - - - - - - - - PAS_5 CMS1_k127_565310_2 1007105.PT7_1206 1.166e-43 160.0 COG0477@1|root,COG2814@2|Bacteria,1MX2P@1224|Proteobacteria,2VIIJ@28216|Betaproteobacteria 28216|Betaproteobacteria EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 CMS1_k127_56655_1 1187851.A33M_3456 3.187e-199 624.0 COG4174@1|root,COG4174@2|Bacteria,1MVKE@1224|Proteobacteria,2TQJD@28211|Alphaproteobacteria,3FCHW@34008|Rhodovulum 28211|Alphaproteobacteria U Binding-protein-dependent transport system inner membrane component yejB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0022857,GO:0035672,GO:0042221,GO:0042493,GO:0042884,GO:0042886,GO:0042891,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944 - ko:K13894 ko02010,map02010 M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.21,3.A.1.5.24 - - BPD_transp_1 CMS1_k127_56655_0 1429916.X566_06785 3.583e-293 910.0 COG4166@1|root,COG4166@2|Bacteria,1MUVU@1224|Proteobacteria,2TQJX@28211|Alphaproteobacteria,3JTJ1@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Bacterial extracellular solute-binding proteins, family 5 Middle yejA - - ko:K13893 ko02010,map02010 M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.21,3.A.1.5.24 - - SBP_bac_5 CMS1_k127_56655_2 323097.Nham_0378 2.786e-34 132.0 COG4166@1|root,COG4166@2|Bacteria,1MUVU@1224|Proteobacteria,2TQJX@28211|Alphaproteobacteria,3JTQZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Bacterial extracellular solute-binding proteins, family 5 Middle MA20_18500 - - ko:K13893 ko02010,map02010 M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.21,3.A.1.5.24 - - SBP_bac_5 CMS1_k127_5668203_2 1123392.AQWL01000008_gene1266 7.298e-72 244.0 COG2603@1|root,COG2603@2|Bacteria,1N4T5@1224|Proteobacteria,2VIMH@28216|Betaproteobacteria,1KSVD@119069|Hydrogenophilales 119069|Hydrogenophilales H Rhodanese Homology Domain - - - ko:K06917 - - - - ko00000,ko01000,ko03016 - - - Rhodanese CMS1_k127_5668203_4 1123392.AQWL01000008_gene1265 4.905e-17 82.0 2BHYP@1|root,32C2Z@2|Bacteria,1PWUR@1224|Proteobacteria,2WCDI@28216|Betaproteobacteria,1KTGT@119069|Hydrogenophilales 119069|Hydrogenophilales - - - - - - - - - - - - - - - CMS1_k127_5668203_0 292415.Tbd_1756 2.89e-87 289.0 COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,2VRG9@28216|Betaproteobacteria,1KRM7@119069|Hydrogenophilales 119069|Hydrogenophilales O SmpB protein - - - ko:K03664 - - - - ko00000 - - - SmpB CMS1_k127_5668203_1 1123392.AQWL01000008_gene1263 2.193e-81 271.0 COG2867@1|root,COG2867@2|Bacteria,1RGUH@1224|Proteobacteria,2VR4X@28216|Betaproteobacteria,1KRPN@119069|Hydrogenophilales 119069|Hydrogenophilales I Polyketide cyclase / dehydrase and lipid transport - - - - - - - - - - - - Polyketide_cyc CMS1_k127_5668203_3 1123392.AQWL01000008_gene1262 1.115e-48 178.0 COG2914@1|root,COG2914@2|Bacteria,1MZCH@1224|Proteobacteria,2VVNX@28216|Betaproteobacteria,1KT66@119069|Hydrogenophilales 119069|Hydrogenophilales S RnfH family Ubiquitin - - - ko:K09801 - - - - ko00000 - - - Ub-RnfH CMS1_k127_5668203_5 1123392.AQWL01000008_gene1261 4.168e-10 60.0 29460@1|root,2ZRKG@2|Bacteria,1PBM2@1224|Proteobacteria,2W5WD@28216|Betaproteobacteria,1KTE9@119069|Hydrogenophilales 119069|Hydrogenophilales - - - - - ko:K06078 - - - - ko00000,ko01011 - - - - CMS1_k127_5673617_3 1304883.KI912532_gene362 3.024e-19 93.0 COG0615@1|root,COG0615@2|Bacteria,1REW3@1224|Proteobacteria,2VR6S@28216|Betaproteobacteria,2KW34@206389|Rhodocyclales 206389|Rhodocyclales H Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - 2.7.7.70 ko:K21345 ko00540,ko01100,map00540,map01100 M00064 R05644 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like CMS1_k127_5673617_1 472759.Nhal_0472 9.596e-44 166.0 COG2823@1|root,COG2823@2|Bacteria,1MUZ2@1224|Proteobacteria,1RY2B@1236|Gammaproteobacteria,1WY1Q@135613|Chromatiales 135613|Chromatiales S PFAM transport-associated - - - - - - - - - - - - BON CMS1_k127_5673617_0 644801.Psest_3273 2.069e-75 258.0 COG0279@1|root,COG0279@2|Bacteria,1NJ8X@1224|Proteobacteria,1RS1Y@1236|Gammaproteobacteria,1Z0IQ@136846|Pseudomonas stutzeri group 1236|Gammaproteobacteria G Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate gmhA - 5.3.1.28 ko:K03271,ko:K12961 ko00540,ko01100,map00540,map01100 M00064 R05645,R09768,R09769 RC00434 ko00000,ko00001,ko00002,ko01000,ko01005,ko03036 - - - SIS_2 CMS1_k127_5673617_2 472759.Nhal_0474 2.271e-26 111.0 COG0792@1|root,COG0792@2|Bacteria,1N6VN@1224|Proteobacteria,1SC8A@1236|Gammaproteobacteria,1WZJZ@135613|Chromatiales 135613|Chromatiales L Belongs to the UPF0102 family - - - ko:K07460 - - - - ko00000 - - - UPF0102 CMS1_k127_5675603_2 1187851.A33M_1540 1.895e-170 539.0 COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,2TQQP@28211|Alphaproteobacteria,3FCMR@34008|Rhodovulum 28211|Alphaproteobacteria H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate moaA - 4.1.99.22 ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09394 RC03420 ko00000,ko00001,ko01000 - - - Fer4_12,Mob_synth_C,Radical_SAM CMS1_k127_5675603_1 991905.SL003B_0823 2.461e-179 567.0 COG4663@1|root,COG4663@2|Bacteria,1MVMD@1224|Proteobacteria,2TS4J@28211|Alphaproteobacteria,4BPUP@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria Q Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - - - - - - - - - - DctP CMS1_k127_5675603_3 991905.SL003B_0824 1.287e-113 378.0 COG4665@1|root,COG4665@2|Bacteria,1R4T4@1224|Proteobacteria,2U2FK@28211|Alphaproteobacteria,4BREP@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria Q TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - - - - - - - - - - DctQ CMS1_k127_5675603_0 991905.SL003B_0825 5.434e-267 839.0 COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,2TQNR@28211|Alphaproteobacteria,4BPV8@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria Q TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - - - - - - - - - - DctM CMS1_k127_5676888_0 1245469.S58_38120 1.835e-302 937.0 COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,2TQPM@28211|Alphaproteobacteria,3JU26@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - - GATase_6,SIS CMS1_k127_5676888_1 883078.HMPREF9695_01904 2.197e-104 343.0 COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,2TQPS@28211|Alphaproteobacteria,3JU8H@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain glmU - 2.3.1.157,2.7.7.23 ko:K04042,ko:K11528 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transf_3 CMS1_k127_5686985_3 1123508.JH636443_gene4982 7.736e-101 340.0 COG0491@1|root,COG0491@2|Bacteria,2IXNH@203682|Planctomycetes 203682|Planctomycetes S Metallo-beta-lactamase superfamily - - - - - - - - - - - - - CMS1_k127_5686985_5 272630.MexAM1_META1p2995 2.248e-51 188.0 COG1376@1|root,COG1376@2|Bacteria,1MUAB@1224|Proteobacteria,2TTXM@28211|Alphaproteobacteria,1JU2J@119045|Methylobacteriaceae 28211|Alphaproteobacteria S PFAM ErfK YbiS YcfS YnhG family protein MA20_01915 - - - - - - - - - - - YkuD CMS1_k127_5686985_6 398525.KB900701_gene7628 8.097e-24 103.0 2DRMU@1|root,33CBD@2|Bacteria,1N0DA@1224|Proteobacteria,2UCNE@28211|Alphaproteobacteria,3K0AI@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_5686985_2 631362.Thi970DRAFT_04763 1.746e-176 557.0 COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,1RMF2@1236|Gammaproteobacteria,1X0ZR@135613|Chromatiales 135613|Chromatiales O HflC and HflK could regulate a protease - - - - - - - - - - - - Band_7 CMS1_k127_5686985_1 331869.BAL199_28440 1.795e-189 597.0 COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,2TRTP@28211|Alphaproteobacteria,4BP7N@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria O HflC and HflK could encode or regulate a protease hflK - - ko:K04088 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7,HflK_N CMS1_k127_5686985_7 1037409.BJ6T_31870 1.713e-18 90.0 2E46N@1|root,32Z2M@2|Bacteria,1N6SH@1224|Proteobacteria,2UHDJ@28211|Alphaproteobacteria,3K55U@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_5686985_0 1297865.APJD01000003_gene6462 0.0 1050.0 COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2TQJR@28211|Alphaproteobacteria,3JV4X@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Acetyl-coenzyme A synthetase N-terminus prpE GO:0003674,GO:0003824,GO:0003987,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0017144,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046950,GO:0046951,GO:0070013,GO:0071704,GO:1901568,GO:1901570,GO:1901576,GO:1902224 6.2.1.1,6.2.1.17 ko:K01895,ko:K01908 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C CMS1_k127_5686985_4 1187851.A33M_2048 1.993e-59 214.0 COG0730@1|root,COG0730@2|Bacteria,1MVY3@1224|Proteobacteria,2TU6M@28211|Alphaproteobacteria,3FDCS@34008|Rhodovulum 28211|Alphaproteobacteria S Sulfite exporter TauE/SafE - - - ko:K07090 - - - - ko00000 - - - TauE CMS1_k127_5687620_3 1429916.X566_19185 8.196e-189 601.0 COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,2TR3B@28211|Alphaproteobacteria,3JR89@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane lptD - - ko:K04744 - - - - ko00000,ko02000 1.B.42.1 - - OstA,OstA_C CMS1_k127_5687620_13 883080.HMPREF9697_01043 1.023e-75 267.0 COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,2TSJ3@28211|Alphaproteobacteria,3JRHX@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O SurA N-terminal domain surA - 5.2.1.8 ko:K03771 - - - - ko00000,ko01000,ko03110 - - - Rotamase,SurA_N,SurA_N_3 CMS1_k127_5687620_6 1197906.CAJQ02000011_gene1025 6.235e-140 454.0 COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,2TSKF@28211|Alphaproteobacteria,3JUN8@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) pdxA - 1.1.1.262 ko:K00097 ko00750,ko01100,map00750,map01100 M00124 R05681,R05837,R07406 RC00089,RC00675,RC01475 ko00000,ko00001,ko00002,ko01000 - - - PdxA CMS1_k127_5687620_8 1429916.X566_19170 3.778e-127 414.0 COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,2TRD9@28211|Alphaproteobacteria,3JS7D@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits ksgA GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 ko:K02528 - - R10716 RC00003,RC03257 ko00000,ko01000,ko03009 - - - RrnaAD CMS1_k127_5687620_12 323098.Nwi_1683 1.343e-86 291.0 COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,2TSCQ@28211|Alphaproteobacteria,3JQSY@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria F Essential for recycling GMP and indirectly, cGMP gmk GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_kin CMS1_k127_5687620_9 1187851.A33M_2663 6.702e-119 389.0 COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,2TS81@28211|Alphaproteobacteria,3FD1P@34008|Rhodovulum 28211|Alphaproteobacteria S Domain of unknown function (DUF1732) yicC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - DUF1732,YicC_N CMS1_k127_5687620_4 1187851.A33M_2664 5.039e-155 499.0 COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,2TR89@28211|Alphaproteobacteria,3FCXZ@34008|Rhodovulum 28211|Alphaproteobacteria S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation mltG - - ko:K07082 - - - - ko00000 - - - YceG CMS1_k127_5687620_1 652103.Rpdx1_2355 7.819e-227 708.0 COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,2TR32@28211|Alphaproteobacteria,3JU0T@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP fabF GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt CMS1_k127_5687620_16 1187851.A33M_2668 1.054e-40 154.0 COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,2UBWW@28211|Alphaproteobacteria,3FD7I@34008|Rhodovulum 28211|Alphaproteobacteria IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding CMS1_k127_5687620_10 504832.OCAR_6369 1.183e-108 358.0 COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,2TQZG@28211|Alphaproteobacteria,3JW0B@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria IQ KR domain fabG GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 CMS1_k127_5687620_7 1187851.A33M_2670 1.012e-136 442.0 COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,2TRTT@28211|Alphaproteobacteria,3FCG8@34008|Rhodovulum 28211|Alphaproteobacteria I Acyl transferase domain fabD GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.39 ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyl_transf_1 CMS1_k127_5687620_15 1187851.A33M_2672 4.185e-52 192.0 COG0360@1|root,COG0360@2|Bacteria,1RH82@1224|Proteobacteria,2U767@28211|Alphaproteobacteria,3FD9E@34008|Rhodovulum 28211|Alphaproteobacteria J Binds together with S18 to 16S ribosomal RNA rpsF GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - ko:K02990 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S6 CMS1_k127_5687620_17 1096546.WYO_1681 1.308e-39 147.0 COG0238@1|root,COG0238@2|Bacteria,1MZ8U@1224|Proteobacteria,2UC13@28211|Alphaproteobacteria,1JV98@119045|Methylobacteriaceae 28211|Alphaproteobacteria J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit rpsR GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02963 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S18 CMS1_k127_5687620_11 1187851.A33M_2674 7.642e-94 317.0 28MUE@1|root,2ZB2B@2|Bacteria,1N3YU@1224|Proteobacteria,2TUD9@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - DUF2232 CMS1_k127_5687620_14 1429916.X566_18965 5.673e-67 234.0 COG0359@1|root,COG0359@2|Bacteria,1RD0R@1224|Proteobacteria,2TSC9@28211|Alphaproteobacteria,3JSJC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Binds to the 23S rRNA rplI GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02939 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L9_C,Ribosomal_L9_N CMS1_k127_5687620_19 1245469.S58_40710 9.248e-14 80.0 296J5@1|root,30YBZ@2|Bacteria,1RIBZ@1224|Proteobacteria,2U9V4@28211|Alphaproteobacteria,3JZIN@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_5687620_2 196490.AUEZ01000084_gene1301 9.797e-198 623.0 COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,2TR8K@28211|Alphaproteobacteria,3JSP4@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Mycolic acid cyclopropane synthetase cfa2 - 2.1.1.79 ko:K00574 - - - - ko00000,ko01000 - - - CMAS CMS1_k127_5687620_0 1040989.AWZU01000020_gene2072 1.342e-235 740.0 COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,2TSF9@28211|Alphaproteobacteria,3JRJJ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins dnaB - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C CMS1_k127_5687620_5 1040989.AWZU01000020_gene2071 1.302e-144 468.0 COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,2TQKD@28211|Alphaproteobacteria,3JT0R@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids alr - 5.1.1.1 ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011 - - - Ala_racemase_C,Ala_racemase_N CMS1_k127_5687620_18 335659.S23_42030 7.102e-15 77.0 COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,2TS6F@28211|Alphaproteobacteria,3JR45@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function radA - - ko:K04485 - - - - ko00000,ko03400 - - - AAA_25,ATPase,ChlI CMS1_k127_5697611_1 1131269.AQVV01000030_gene270 1.793e-111 368.0 COG0053@1|root,COG0053@2|Bacteria 2|Bacteria P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family catA - - - - - - - - - - - Cation_efflux,ZT_dimer CMS1_k127_5697611_0 622637.KE124774_gene3248 3.689e-189 600.0 COG3385@1|root,COG3385@2|Bacteria,1QURV@1224|Proteobacteria,2TW56@28211|Alphaproteobacteria,371IT@31993|Methylocystaceae 28211|Alphaproteobacteria L Transposase DDE domain group 1 - - - - - - - - - - - - DDE_Tnp_1_4 CMS1_k127_5700036_18 113395.AXAI01000011_gene6519 7.671e-05 46.0 COG0520@1|root,COG0520@2|Bacteria,1QEVJ@1224|Proteobacteria,2TX67@28211|Alphaproteobacteria,3JTSQ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - - - - - - - - - - - CMS1_k127_5700036_2 1123229.AUBC01000010_gene3344 5.88e-143 481.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria,3JTJB@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T CHASE - - - - - - - - - - - - CHASE,CHASE4,EAL,GGDEF,PAS_9 CMS1_k127_5700036_13 504832.OCAR_4808 1.496e-55 199.0 COG3439@1|root,COG3439@2|Bacteria,1RH9Z@1224|Proteobacteria,2UAEV@28211|Alphaproteobacteria,3JZK9@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Domain of unknown function DUF302 - - - - - - - - - - - - DUF302 CMS1_k127_5700036_3 1297863.APJF01000012_gene1562 7.013e-128 412.0 COG3484@1|root,COG3484@2|Bacteria,1N057@1224|Proteobacteria,2U09K@28211|Alphaproteobacteria,3JRRE@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O Proteasome-type protease MA20_32445 - - ko:K07395 - - - - ko00000 - - - Proteasome CMS1_k127_5700036_4 666684.AfiDRAFT_3655 6.354e-115 376.0 COG1305@1|root,COG1305@2|Bacteria,1MVMI@1224|Proteobacteria,2TTZY@28211|Alphaproteobacteria,3JS6U@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Bacterial transglutaminase-like N-terminal region MA20_32430 - - - - - - - - - - - Bact_transglu_N,Transglut_core CMS1_k127_5700036_1 1187851.A33M_2544 1.916e-150 480.0 COG2307@1|root,COG2307@2|Bacteria,1MVZK@1224|Proteobacteria,2TQUM@28211|Alphaproteobacteria,3FD5C@34008|Rhodovulum 28211|Alphaproteobacteria S A predicted alpha-helical domain with a conserved ER motif. MA20_32425 - - - - - - - - - - - Alpha-E CMS1_k127_5700036_0 1168059.KB899087_gene775 1.718e-251 801.0 COG2308@1|root,COG2308@2|Bacteria,1MUAD@1224|Proteobacteria,2TRI7@28211|Alphaproteobacteria,3EY68@335928|Xanthobacteraceae 28211|Alphaproteobacteria S Circularly permuted ATP-grasp type 2 MA20_32420 - - - - - - - - - - - CP_ATPgrasp_2 CMS1_k127_5700036_6 1429916.X566_23830 6.247e-101 334.0 COG1058@1|root,COG1058@2|Bacteria,1MVG6@1224|Proteobacteria,2TU5C@28211|Alphaproteobacteria,3JR92@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Probable molybdopterin binding domain cinA1 - - - - - - - - - - - MoCF_biosynth CMS1_k127_5700036_14 1380355.JNIJ01000004_gene2908 3.318e-47 176.0 COG2062@1|root,COG2062@2|Bacteria,1RIC8@1224|Proteobacteria,2U9B3@28211|Alphaproteobacteria,3K292@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Phosphoglycerate mutase family - - - - - - - - - - - - His_Phos_1 CMS1_k127_5700036_12 1133849.O3I_007575 4.64e-57 205.0 COG3485@1|root,COG3485@2|Bacteria,2GNNC@201174|Actinobacteria 201174|Actinobacteria Q catechol 1,2-dioxygenase - - - - - - - - - - - - Dioxygenase_C CMS1_k127_5700036_7 1211115.ALIQ01000055_gene2809 8.754e-82 275.0 COG2236@1|root,COG2236@2|Bacteria,1MWNE@1224|Proteobacteria,2TUXK@28211|Alphaproteobacteria,3NB6A@45404|Beijerinckiaceae 28211|Alphaproteobacteria F Phosphoribosyl transferase domain gpt - 2.4.2.22 ko:K00769 ko00230,ko01100,ko01110,map00230,map01100,map01110 - R01229,R02142 RC00063,RC00122 ko00000,ko00001,ko01000 - - - Pribosyltran CMS1_k127_5700036_11 196490.AUEZ01000066_gene2430 6.495e-59 208.0 COG1917@1|root,COG1917@2|Bacteria,1RAGP@1224|Proteobacteria,2U5F3@28211|Alphaproteobacteria,3JYCW@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ChrR Cupin-like domain - - - - - - - - - - - - Cupin_7 CMS1_k127_5700036_8 189753.AXAS01000012_gene4337 1.017e-79 278.0 COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind CMS1_k127_5700036_10 985054.JQEZ01000002_gene3276 2.348e-66 238.0 COG0500@1|root,COG2226@2|Bacteria,1R6ZI@1224|Proteobacteria,2TRC6@28211|Alphaproteobacteria,4NCS9@97050|Ruegeria 28211|Alphaproteobacteria Q Mycolic acid cyclopropane synthetase - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 CMS1_k127_5700036_16 1298867.AUES01000048_gene4585 1.968e-17 84.0 COG2984@1|root,COG2984@2|Bacteria 2|Bacteria S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind CMS1_k127_5700036_9 1411123.JQNH01000001_gene2362 2.556e-70 245.0 COG0664@1|root,COG0664@2|Bacteria,1Q93V@1224|Proteobacteria,2TTEY@28211|Alphaproteobacteria 28211|Alphaproteobacteria T cyclic nucleotide-binding MA20_09210 - - - - - - - - - - - Imp-YgjV,cNMP_binding CMS1_k127_5700036_5 63737.Npun_R2053 1.146e-101 346.0 COG1073@1|root,COG1073@2|Bacteria,1GGWP@1117|Cyanobacteria,1HTF4@1161|Nostocales 1117|Cyanobacteria S Alpha/beta hydrolase of unknown function (DUF1100) - - - - - - - - - - - - DUF1100 CMS1_k127_5700036_17 1122180.Lokhon_02507 1.99e-13 74.0 COG0582@1|root,COG0582@2|Bacteria,1RBMJ@1224|Proteobacteria,2U0ET@28211|Alphaproteobacteria 28211|Alphaproteobacteria L Belongs to the 'phage' integrase family - - - - - - - - - - - - Phage_int_SAM_3,Phage_integrase CMS1_k127_5700036_15 596152.DesU5LDRAFT_3337 1.369e-42 158.0 COG1387@1|root,COG1387@2|Bacteria,1MYXV@1224|Proteobacteria,42MQX@68525|delta/epsilon subdivisions,2WKUP@28221|Deltaproteobacteria,2MA0I@213115|Desulfovibrionales 28221|Deltaproteobacteria E pfam php - - - ko:K02347 - - - - ko00000,ko03400 - - - DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP CMS1_k127_5703188_2 991905.SL003B_2057 1.348e-35 137.0 COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,2TQPA@28211|Alphaproteobacteria,4BPFW@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - S4,tRNA-synt_1b CMS1_k127_5703188_1 113395.AXAI01000023_gene7148 3.099e-104 351.0 COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,2TS8U@28211|Alphaproteobacteria,3JR6V@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell lpxD - 2.3.1.191 ko:K02536 ko00540,ko01100,map00540,map01100 M00060 R04550 RC00039,RC00166 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Hexapep,Hexapep_2,LpxD CMS1_k127_5703188_3 1150469.RSPPHO_02819 2.792e-13 72.0 COG0236@1|root,COG0236@2|Bacteria,1PJV2@1224|Proteobacteria,2VCR2@28211|Alphaproteobacteria,2JYD3@204441|Rhodospirillales 204441|Rhodospirillales IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis - - - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding CMS1_k127_5703188_0 1150469.RSPPHO_02818 1.538e-126 415.0 COG0304@1|root,COG0304@2|Bacteria,1MV30@1224|Proteobacteria,2TRYK@28211|Alphaproteobacteria,2JW3W@204441|Rhodospirillales 204441|Rhodospirillales IQ Beta-ketoacyl synthase, C-terminal domain - - - ko:K14660 - - - - ko00000,ko01000 - - - Ketoacyl-synt_C,ketoacyl-synt CMS1_k127_57670_1 1187851.A33M_2193 1.028e-99 330.0 COG2135@1|root,COG2135@2|Bacteria,1RER4@1224|Proteobacteria,2U0W2@28211|Alphaproteobacteria,3FE8N@34008|Rhodovulum 28211|Alphaproteobacteria S SOS response associated peptidase (SRAP) MA20_42060 - - - - - - - - - - - SRAP CMS1_k127_57670_0 1211115.ALIQ01000072_gene3844 1.195e-116 382.0 COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2TRYI@28211|Alphaproteobacteria,3N9YG@45404|Beijerinckiaceae 28211|Alphaproteobacteria C FAD linked oxidases, C-terminal domain MA20_42035 GO:0000166,GO:0003674,GO:0003824,GO:0004457,GO:0004458,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006089,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016053,GO:0016491,GO:0016614,GO:0016898,GO:0019249,GO:0019516,GO:0019752,GO:0022900,GO:0022904,GO:0030447,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046394,GO:0048037,GO:0050660,GO:0050662,GO:0051990,GO:0055114,GO:0071704,GO:0071949,GO:0072330,GO:0097159,GO:0099615,GO:1901265,GO:1901363,GO:1901576,GO:1901615,GO:1901617 1.1.2.4 ko:K00102 ko00620,map00620 - R00197 RC00044 ko00000,ko00001,ko01000 - - - FAD-oxidase_C,FAD_binding_4 CMS1_k127_5788759_3 471853.Bcav_1486 9.904e-17 81.0 COG1028@1|root,COG1028@2|Bacteria,2GK78@201174|Actinobacteria 201174|Actinobacteria IQ PFAM Short-chain dehydrogenase reductase SDR - - - - - - - - - - - - adh_short_C2 CMS1_k127_5788759_0 1187851.A33M_0757 1.87e-147 472.0 COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,2TSX9@28211|Alphaproteobacteria,3FCKD@34008|Rhodovulum 28211|Alphaproteobacteria BQ Histone deacetylase domain MA20_07590 - - ko:K04768 - - - - ko00000 - - - Hist_deacetyl CMS1_k127_5788759_1 1231391.AMZF01000007_gene1511 7.318e-91 309.0 COG0715@1|root,COG0715@2|Bacteria,1RCBF@1224|Proteobacteria,2VZS3@28216|Betaproteobacteria 28216|Betaproteobacteria P NMT1-like family - - - - - - - - - - - - NMT1 CMS1_k127_5788759_2 981384.AEYW01000001_gene1462 4.924e-40 150.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQW5@28211|Alphaproteobacteria 28211|Alphaproteobacteria G COG1593 TRAP-type C4-dicarboxylate transport system large permease component - - - ko:K11690 ko02020,map02020 - - - ko00000,ko00001,ko02000 2.A.56.1 - - DctM CMS1_k127_5820011_14 1120972.AUMH01000033_gene3067 9.985e-49 189.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HAKV@91061|Bacilli,277WW@186823|Alicyclobacillaceae 91061|Bacilli I Acyl-CoA dehydrogenase, N-terminal domain acdA - 1.3.8.1,1.3.8.7 ko:K00248,ko:K00249 ko00071,ko00280,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01178,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00120,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N CMS1_k127_5820011_7 1298867.AUES01000001_gene1724 1.909e-94 320.0 COG0673@1|root,COG0673@2|Bacteria,1MU8F@1224|Proteobacteria,2U12U@28211|Alphaproteobacteria,3JX1N@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C CMS1_k127_5820011_16 1125973.JNLC01000010_gene1408 3.674e-48 179.0 COG1917@1|root,COG1917@2|Bacteria 2|Bacteria L Cupin 2, conserved barrel domain protein MA20_40115 - - - - - - - - - - - Cupin_2 CMS1_k127_5820011_17 172088.AUGA01000016_gene2484 1.034e-37 151.0 COG1409@1|root,COG1409@2|Bacteria,1RHP4@1224|Proteobacteria,2U9B6@28211|Alphaproteobacteria,3K0V6@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Calcineurin-like phosphoesterase - - - - - - - - - - - - Metallophos CMS1_k127_5820011_21 571166.KI421509_gene2063 1.8e-11 65.0 2AE9B@1|root,3143E@2|Bacteria,1QXVV@1224|Proteobacteria,2U9MI@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_5820011_19 717785.HYPMC_1318 1.827e-25 106.0 2CHQV@1|root,33N02@2|Bacteria,1NM7K@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - CMS1_k127_5820011_2 1429916.X566_03085 1.697e-194 624.0 COG0784@1|root,COG2202@1|root,COG3437@1|root,COG3920@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG3437@2|Bacteria,COG3920@2|Bacteria,1NC9X@1224|Proteobacteria,2TT77@28211|Alphaproteobacteria 28211|Alphaproteobacteria T Histidine kinase - - - - - - - - - - - - HWE_HK,PAS_3,Response_reg CMS1_k127_5820011_0 460265.Mnod_6353 0.0 2295.0 COG0642@1|root,COG0745@1|root,COG0784@1|root,COG0840@1|root,COG2203@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG0840@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2TRHH@28211|Alphaproteobacteria,1JZII@119045|Methylobacteriaceae 28211|Alphaproteobacteria T histidine kinase HAMP region domain protein - - 2.7.13.3 ko:K07716 ko02020,ko04112,map02020,map04112 M00511 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - CHASE3,GAF_2,HAMP,HATPase_c,HisKA,PAS_3,Response_reg,TPR_12 CMS1_k127_5820011_15 224911.27351250 1.097e-48 184.0 COG0797@1|root,COG0797@2|Bacteria,1RDQ1@1224|Proteobacteria,2U7GC@28211|Alphaproteobacteria,3JYVJ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Lytic transglycolase - - - ko:K03642 - - - - ko00000 - - - DPBB_1 CMS1_k127_5820011_9 1238182.C882_0312 6.991e-84 284.0 COG1765@1|root,COG1765@2|Bacteria,1RBJN@1224|Proteobacteria,2VF54@28211|Alphaproteobacteria 28211|Alphaproteobacteria O OsmC-like protein - - - - - - - - - - - - OsmC CMS1_k127_5820011_4 290397.Adeh_2255 5.311e-145 475.0 COG2072@1|root,COG2072@2|Bacteria,1MWPJ@1224|Proteobacteria,437TD@68525|delta/epsilon subdivisions,2WT6I@28221|Deltaproteobacteria,2YX1E@29|Myxococcales 28221|Deltaproteobacteria C L-lysine 6-monooxygenase (NADPH-requiring) - - - ko:K07222 - - - - ko00000 - - - Pyr_redox_3 CMS1_k127_5820011_12 1169143.KB911037_gene4044 2.411e-78 279.0 COG2267@1|root,COG2267@2|Bacteria,1R72P@1224|Proteobacteria,2WH24@28216|Betaproteobacteria,1K5AI@119060|Burkholderiaceae 28216|Betaproteobacteria I alpha/beta hydrolase fold - - - - - - - - - - - - Abhydrolase_6 CMS1_k127_5820011_13 1211115.ALIQ01000190_gene914 5.196e-73 263.0 COG2271@1|root,COG2271@2|Bacteria,1QVY6@1224|Proteobacteria,2TWTV@28211|Alphaproteobacteria,3NBUK@45404|Beijerinckiaceae 28211|Alphaproteobacteria G Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 CMS1_k127_5820011_5 640511.BC1002_5570 6.024e-127 445.0 COG3629@1|root,COG3899@1|root,COG3629@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2VKH1@28216|Betaproteobacteria,1JZT2@119060|Burkholderiaceae 28216|Betaproteobacteria T adenylyl cyclase class-3 4 guanylyl cyclase - - - - - - - - - - - - AAA_16 CMS1_k127_5820011_20 251229.Chro_3261 1.267e-15 84.0 2C1W2@1|root,31MWG@2|Bacteria,1G6PN@1117|Cyanobacteria 1117|Cyanobacteria S Protein of unknown function (DUF4242) - - - - - - - - - - - - DUF4242 CMS1_k127_5820011_22 1121022.ABENE_15855 7.705e-05 51.0 COG2198@1|root,COG2198@2|Bacteria,1NENQ@1224|Proteobacteria,2TSW1@28211|Alphaproteobacteria,2KGRV@204458|Caulobacterales 204458|Caulobacterales T Histidine kinase - - - - - - - - - - - - Hpt CMS1_k127_5820011_18 190650.CC_0440 9.823e-28 121.0 COG0784@1|root,COG0784@2|Bacteria,1RHY1@1224|Proteobacteria,2UATB@28211|Alphaproteobacteria,2KGPW@204458|Caulobacterales 204458|Caulobacterales T Response regulator receiver - - - - - - - - - - - - Response_reg CMS1_k127_5820011_10 1121861.KB899919_gene2702 8.201e-79 266.0 COG4032@1|root,COG4032@2|Bacteria,1R53S@1224|Proteobacteria,2TT20@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Sulfopyruvate decarboxylase subunit alpha MA20_15000 - 4.1.1.79 ko:K06034 ko00680,ko01120,map00680,map01120 M00358 R05774 RC00506 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_N CMS1_k127_5820011_8 1380355.JNIJ01000009_gene1662 1.353e-84 292.0 COG0028@1|root,COG0028@2|Bacteria,1R6QP@1224|Proteobacteria,2TUEF@28211|Alphaproteobacteria,3JT5U@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria EH Thiamine pyrophosphate enzyme, C-terminal TPP binding domain MA20_15005 - 4.1.1.79 ko:K13039 ko00680,ko01120,map00680,map01120 M00358 R05774 RC00506 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C CMS1_k127_5820011_11 1089545.KB913037_gene1306 1.985e-78 280.0 COG2079@1|root,COG2079@2|Bacteria,2GKUR@201174|Actinobacteria,4E4J0@85010|Pseudonocardiales 201174|Actinobacteria S MmgE/PrpD family - - - - - - - - - - - - MmgE_PrpD CMS1_k127_5820011_1 640510.BC1001_5942 6.05e-244 773.0 COG1042@1|root,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,2VI9R@28216|Betaproteobacteria,1K035@119060|Burkholderiaceae 28216|Betaproteobacteria C CoA-binding domain protein - - - ko:K09181 - - - - ko00000 - - - ATP-grasp_5,Acetyltransf_3,Acetyltransf_4,CoA_binding_2,Succ_CoA_lig CMS1_k127_5820011_3 1123060.JONP01000028_gene3705 6.325e-172 567.0 COG1960@1|root,COG1960@2|Bacteria,1MX17@1224|Proteobacteria,2TTRE@28211|Alphaproteobacteria,2JV80@204441|Rhodospirillales 204441|Rhodospirillales I Acyl-CoA dehydrogenase, C-terminal domain - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N CMS1_k127_5820011_6 1187851.A33M_0878 4.168e-101 342.0 COG2271@1|root,COG2271@2|Bacteria,1QTYR@1224|Proteobacteria,2TXM8@28211|Alphaproteobacteria 28211|Alphaproteobacteria G PFAM Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 CMS1_k127_5828301_1 1187851.A33M_1682 8.765e-113 384.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria 28211|Alphaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - CHASE4,EAL,GGDEF,PAS_7 CMS1_k127_5828301_0 1187851.A33M_1683 3.376e-196 621.0 COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,2TRWK@28211|Alphaproteobacteria,3FCGF@34008|Rhodovulum 28211|Alphaproteobacteria P Acts as a magnesium transporter mgtE - - ko:K06213 - - - - ko00000,ko02000 1.A.26.1 - - CBS,MgtE,MgtE_N CMS1_k127_5828301_2 1187851.A33M_1684 7.419e-87 298.0 COG0726@1|root,COG0726@2|Bacteria,1PJQG@1224|Proteobacteria,2TR9X@28211|Alphaproteobacteria 28211|Alphaproteobacteria G polysaccharide deacetylase - - - - - - - - - - - - Polysacc_deac_1 CMS1_k127_5828301_3 246200.SPO0998 5.667e-09 58.0 COG2041@1|root,COG2041@2|Bacteria,1MX9E@1224|Proteobacteria,2TRK0@28211|Alphaproteobacteria,4NBVC@97050|Ruegeria 28211|Alphaproteobacteria S Mo-co oxidoreductase dimerisation domain soxC - - ko:K17225 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 - - - Mo-co_dimer,Oxidored_molyb CMS1_k127_5839446_1 883080.HMPREF9697_02590 1.524e-268 832.0 COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,2TQMY@28211|Alphaproteobacteria,3JRUZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB - - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N,IF2_assoc CMS1_k127_5839446_8 652103.Rpdx1_0185 9.295e-61 212.0 COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,2UCJF@28211|Alphaproteobacteria,3JY9A@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA rbfA - - ko:K02834 - - - - ko00000,ko03009 - - - RBFA CMS1_k127_5839446_3 1187851.A33M_1339 3.001e-159 511.0 COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,2TSJK@28211|Alphaproteobacteria,3FCYI@34008|Rhodovulum 28211|Alphaproteobacteria J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs truB GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 ko:K03177 - - - - ko00000,ko01000,ko03016 - - - TruB-C_2,TruB_C_2,TruB_N CMS1_k127_5839446_10 1187851.A33M_1340 1.689e-38 145.0 COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,2UBRZ@28211|Alphaproteobacteria,3FDBD@34008|Rhodovulum 28211|Alphaproteobacteria J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome rpsO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02956 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S15 CMS1_k127_5839446_0 1144343.PMI41_01037 0.0 1091.0 COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,2TRH3@28211|Alphaproteobacteria,43IV8@69277|Phyllobacteriaceae 28211|Alphaproteobacteria J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction pnp GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - KH_1,PNPase,RNase_PH,RNase_PH_C,S1 CMS1_k127_5839446_9 196367.JNFG01000016_gene4025 9.668e-53 192.0 2DMP1@1|root,32SS8@2|Bacteria,1MZTD@1224|Proteobacteria,2WG6B@28216|Betaproteobacteria,1KIAC@119060|Burkholderiaceae 28216|Betaproteobacteria S Protein of unknown function (DUF3237) - - - - - - - - - - - - DUF3237 CMS1_k127_5839446_7 1298867.AUES01000004_gene722 2.729e-63 224.0 COG0664@1|root,COG0664@2|Bacteria,1MV7G@1224|Proteobacteria,2U1I4@28211|Alphaproteobacteria,3JUCQ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K Transcriptional regulator, Crp Fnr family - - - - - - - - - - - - HTH_Crp_2,cNMP_binding CMS1_k127_5839446_4 318586.Pden_3499 2.772e-155 501.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TQNK@28211|Alphaproteobacteria,2PVKP@265|Paracoccus 28211|Alphaproteobacteria G C4-dicarboxylate ABC transporter permease - - - - - - - - - - - - DctM CMS1_k127_5839446_11 376733.IT41_11230 1.05e-28 121.0 COG3090@1|root,COG3090@2|Bacteria,1N9D4@1224|Proteobacteria,2U7Z5@28211|Alphaproteobacteria,2PX1A@265|Paracoccus 28211|Alphaproteobacteria G Tripartite ATP-independent periplasmic transporters, DctQ component - - - - - - - - - - - - DctQ CMS1_k127_5839446_6 1177928.TH2_05933 9.332e-83 286.0 COG1638@1|root,COG1638@2|Bacteria,1PG0D@1224|Proteobacteria,2TTUQ@28211|Alphaproteobacteria,2JVS5@204441|Rhodospirillales 204441|Rhodospirillales G Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP CMS1_k127_5839446_12 1038859.AXAU01000015_gene1060 1.036e-06 51.0 COG3415@1|root,COG3415@2|Bacteria,1RJ69@1224|Proteobacteria,2UB2N@28211|Alphaproteobacteria,3K101@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L 'Paired box' domain - - - ko:K07499 - - - - ko00000 - - - HTH_23,HTH_32,HTH_Tnp_IS630,PAX CMS1_k127_5839446_5 504832.OCAR_4501 3.832e-113 372.0 COG0583@1|root,COG0583@2|Bacteria,1MVA1@1224|Proteobacteria,2TSUS@28211|Alphaproteobacteria,3JV0U@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K LysR family oxyR - - ko:K04761 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - HTH_1,LysR_substrate CMS1_k127_5839446_2 172088.AUGA01000001_gene6424 8.631e-177 554.0 COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,2TQJ7@28211|Alphaproteobacteria,3JRQT@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity katG GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 ko:K03782 ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110 - R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906 RC00034,RC00213,RC00767,RC02141 ko00000,ko00001,ko01000 - - - peroxidase CMS1_k127_5878697_2 1187851.A33M_4197 1.345e-140 451.0 COG0662@1|root,COG0836@1|root,COG0662@2|Bacteria,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,2TT0R@28211|Alphaproteobacteria,3FCHV@34008|Rhodovulum 28211|Alphaproteobacteria GM Mannose-6-phosphate isomerase manC - 2.7.7.13,5.3.1.8 ko:K00971,ko:K16011 ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025 M00114,M00361,M00362 R00885,R01819 RC00002,RC00376 ko00000,ko00001,ko00002,ko01000 - - - MannoseP_isomer,NTP_transferase CMS1_k127_5878697_1 196490.AUEZ01000039_gene7059 3.229e-205 646.0 COG2723@1|root,COG2723@2|Bacteria,1MWG6@1224|Proteobacteria,2TSRN@28211|Alphaproteobacteria,3JQT9@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - 3.2.1.21 ko:K05350 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - - - Glyco_hydro_1 CMS1_k127_5878697_0 1429916.X566_20415 8.971e-226 717.0 COG4178@1|root,COG4178@2|Bacteria,1MW09@1224|Proteobacteria,2TS9Q@28211|Alphaproteobacteria,3JTIR@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ABC transporter transmembrane region 2 MA20_43525 - - ko:K02471 ko02010,map02010 - - - ko00000,ko00001,ko02000 3.A.1.203.11,3.A.1.203.4 - - ABC_membrane_2,ABC_tran CMS1_k127_5892284_0 663610.JQKO01000013_gene1800 4.665e-283 879.0 COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,2U0IK@28211|Alphaproteobacteria,3NC65@45404|Beijerinckiaceae 28211|Alphaproteobacteria O Found in ATP-dependent protease La (LON) MA20_45155 - 3.4.21.53 ko:K01338 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - AAA,LON_substr_bdg,Lon_C CMS1_k127_5892284_12 392499.Swit_1147 1.677e-46 171.0 COG0071@1|root,COG0071@2|Bacteria,1N0RH@1224|Proteobacteria,2UE1E@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Belongs to the small heat shock protein (HSP20) family MA20_45160 - - - - - - - - - - - HSP20 CMS1_k127_5892284_10 639283.Snov_3541 3.081e-57 207.0 2E4J2@1|root,32ZE4@2|Bacteria,1N7YM@1224|Proteobacteria,2UBV9@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF3775) - - - - - - - - - - - - DUF3775 CMS1_k127_5892284_8 631454.N177_1761 2.385e-70 243.0 COG1278@1|root,COG1278@2|Bacteria,1QW5N@1224|Proteobacteria,2U8SB@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Sigma 54 modulation protein / S30EA ribosomal protein - - - - - - - - - - - - CSD,Ribosomal_S30AE CMS1_k127_5892284_11 187272.Mlg_1729 8.687e-48 183.0 COG1371@1|root,COG1371@2|Bacteria,1RJU0@1224|Proteobacteria,1S8F6@1236|Gammaproteobacteria,1X1E9@135613|Chromatiales 135613|Chromatiales S Archease protein family (MTH1598/TM1083) - - - - - - - - - - - - Archease CMS1_k127_5892284_1 187272.Mlg_1728 2.599e-221 694.0 COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,1RMXH@1236|Gammaproteobacteria,1WW29@135613|Chromatiales 135613|Chromatiales S PFAM Uncharacterised protein family UPF0027 rtcB - 6.5.1.3 ko:K14415 - - - - ko00000,ko01000,ko03016 - - - RtcB CMS1_k127_5892284_5 639283.Snov_0825 1.797e-102 336.0 COG1335@1|root,COG1335@2|Bacteria,1MUGW@1224|Proteobacteria,2TRMB@28211|Alphaproteobacteria,3EZBF@335928|Xanthobacteraceae 28211|Alphaproteobacteria Q Isochorismatase family pncA - 3.5.1.19 ko:K08281 ko00760,ko01100,map00760,map01100 - R01268 RC00100 ko00000,ko00001,ko01000 - - - Isochorismatase CMS1_k127_5892284_6 395964.KE386496_gene2822 4.307e-85 289.0 COG1926@1|root,COG1926@2|Bacteria,1RAG8@1224|Proteobacteria,2U5HS@28211|Alphaproteobacteria,3NAXQ@45404|Beijerinckiaceae 28211|Alphaproteobacteria S Phosphoribosyl transferase domain - - - ko:K07100 - - - - ko00000 - - - Erythro_esteras,Pribosyltran CMS1_k127_5892284_9 366602.Caul_4233 8.771e-69 245.0 COG1073@1|root,COG1926@1|root,COG2312@1|root,COG1073@2|Bacteria,COG1926@2|Bacteria,COG2312@2|Bacteria,1MU2S@1224|Proteobacteria,2TY7R@28211|Alphaproteobacteria,2KHES@204458|Caulobacterales 204458|Caulobacterales S Erythromycin esterase - - - - - - - - - - - - DLH,Erythro_esteras,Pribosyltran CMS1_k127_5892284_4 1304877.KI519399_gene6062 6.217e-108 360.0 COG2187@1|root,COG2187@2|Bacteria,1MU9M@1224|Proteobacteria,2TQJN@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Aminoglycoside phosphotransferase - - - - - - - - - - - - - CMS1_k127_5892284_2 639283.Snov_1191 4.749e-128 419.0 COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,2TR4Y@28211|Alphaproteobacteria,3EYA1@335928|Xanthobacteraceae 28211|Alphaproteobacteria F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) prsA - 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyl_synth,Pribosyltran,Pribosyltran_N CMS1_k127_5892284_7 1038862.KB893865_gene4555 5.59e-83 278.0 COG1595@1|root,COG1595@2|Bacteria,1MZMC@1224|Proteobacteria,2TUUZ@28211|Alphaproteobacteria,3JSQZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K Belongs to the sigma-70 factor family. ECF subfamily sigH - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 CMS1_k127_5892284_14 639283.Snov_0052 1.81e-11 67.0 28XZJ@1|root,31048@2|Bacteria,1PN4D@1224|Proteobacteria,2V0QU@28211|Alphaproteobacteria,3F22R@335928|Xanthobacteraceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_5892284_3 1187851.A33M_0628 2.754e-115 378.0 COG0784@1|root,COG0784@2|Bacteria,1MX3Y@1224|Proteobacteria,2TT2R@28211|Alphaproteobacteria,3FCYF@34008|Rhodovulum 28211|Alphaproteobacteria KT cheY-homologous receiver domain phyR - - - - - - - - - - - Response_reg,Sigma70_r4_2 CMS1_k127_5892284_16 1038860.AXAP01000025_gene1646 0.0002418 49.0 COG4575@1|root,COG4575@2|Bacteria,1RHUR@1224|Proteobacteria,2UAZ1@28211|Alphaproteobacteria,3JZGI@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Bacterial protein of unknown function (DUF883) MA20_18275 - - - - - - - - - - - DUF883 CMS1_k127_5892284_15 1380355.JNIJ01000024_gene2277 0.0001233 46.0 2CPI3@1|root,32SJ7@2|Bacteria,1N1IR@1224|Proteobacteria,2UBVS@28211|Alphaproteobacteria,3JY4X@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF992) - - - - - - - - - - - - DUF992 CMS1_k127_5896507_3 1304878.AUGD01000003_gene2566 7.897e-34 134.0 COG0140@1|root,COG0140@2|Bacteria,1MZEE@1224|Proteobacteria,2UBU3@28211|Alphaproteobacteria,3JZNP@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E phosphoribosyl-ATP diphosphatase activity hisE - 3.6.1.31 ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - PRA-PH CMS1_k127_5896507_1 1187851.A33M_0098 2.252e-160 512.0 COG1072@1|root,COG1072@2|Bacteria,1MV3M@1224|Proteobacteria,2TS7E@28211|Alphaproteobacteria 28211|Alphaproteobacteria F Pantothenic acid kinase coaA GO:0003674,GO:0003824,GO:0004594,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.33 ko:K00867 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - PRK CMS1_k127_5896507_2 1187851.A33M_1470 8.657e-123 402.0 COG3176@1|root,COG3176@2|Bacteria,1MWIM@1224|Proteobacteria,2TUVA@28211|Alphaproteobacteria,3FD5I@34008|Rhodovulum 28211|Alphaproteobacteria S Acetyltransferase (GNAT) domain olsB - 2.3.2.30 ko:K22310 - - - - ko00000,ko01000 - - - Acetyltransf_5 CMS1_k127_5896507_0 189753.AXAS01000031_gene4466 5.148e-223 707.0 COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2TWPZ@28211|Alphaproteobacteria,3JTJD@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,PAS,PAS_4,PAS_8,Response_reg CMS1_k127_5910998_1 1187851.A33M_0100 8.935e-138 440.0 COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,2TQXD@28211|Alphaproteobacteria,3FCSU@34008|Rhodovulum 28211|Alphaproteobacteria E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit hisF GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth CMS1_k127_5910998_2 709797.CSIRO_0925 1.499e-120 392.0 COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,2TRSG@28211|Alphaproteobacteria,3JQMK@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase hisA GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04640 RC00945 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth CMS1_k127_5910998_4 1187851.A33M_0104 1.123e-99 328.0 COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,2TTT4@28211|Alphaproteobacteria,3FCWP@34008|Rhodovulum 28211|Alphaproteobacteria E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR hisH - - ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - - GATase CMS1_k127_5910998_6 316058.RPB_0406 3.692e-41 158.0 2BXM2@1|root,331PK@2|Bacteria,1MUGN@1224|Proteobacteria,2UFNI@28211|Alphaproteobacteria,3JW9M@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF2628) - - - - - - - - - - - - DUF2628 CMS1_k127_5910998_3 335659.S23_01850 3.718e-105 344.0 COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,2TTVV@28211|Alphaproteobacteria,3JU1H@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E imidazoleglycerol-phosphate dehydratase hisB GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.9,3.1.3.15,4.2.1.19 ko:K00817,ko:K01089,ko:K01693 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03013,R03243,R03457 RC00006,RC00017,RC00888,RC00932 ko00000,ko00001,ko00002,ko01000,ko01007 - - - IGPD CMS1_k127_5910998_5 1126627.BAWE01000002_gene1149 2.595e-94 311.0 COG5405@1|root,COG5405@2|Bacteria,1MVF2@1224|Proteobacteria,2TRRE@28211|Alphaproteobacteria,3JRD8@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery hslV - 3.4.25.2 ko:K01419 - - - - ko00000,ko01000,ko01002 - - - Proteasome CMS1_k127_5910998_0 398525.KB900701_gene1563 3.275e-230 719.0 COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,2TRXC@28211|Alphaproteobacteria,3JT4A@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis hslU - - ko:K03667 - - - - ko00000,ko03110 - - - AAA_2,ClpB_D2-small CMS1_k127_5912007_1 1187851.A33M_2443 6.004e-229 721.0 COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,2TRGN@28211|Alphaproteobacteria,3FCQB@34008|Rhodovulum 28211|Alphaproteobacteria G Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom CMS1_k127_5912007_0 1380355.JNIJ01000028_gene657 2.03e-322 1005.0 COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,2TRC1@28211|Alphaproteobacteria,3JRHJ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr GO:0000175,GO:0003674,GO:0003724,GO:0003824,GO:0004386,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008408,GO:0008997,GO:0009056,GO:0009057,GO:0009266,GO:0009409,GO:0009628,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016896,GO:0017111,GO:0019222,GO:0019439,GO:0034458,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - RNB,S1 CMS1_k127_5912007_2 1411123.JQNH01000001_gene1150 4.248e-79 275.0 COG0494@1|root,COG0494@2|Bacteria,1N8EV@1224|Proteobacteria,2TTNV@28211|Alphaproteobacteria 28211|Alphaproteobacteria L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes MA20_36340 - - - - - - - - - - - NUDIX CMS1_k127_5912007_3 744979.R2A130_0252 3.307e-08 55.0 COG0267@1|root,COG0267@2|Bacteria,1N6QV@1224|Proteobacteria,2UF4D@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Belongs to the bacterial ribosomal protein bL33 family rpmG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02913 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L33 CMS1_k127_5938614_1 935548.KI912159_gene1845 1.125e-24 108.0 COG1752@1|root,COG1752@2|Bacteria,1Q82E@1224|Proteobacteria,2TU9N@28211|Alphaproteobacteria,43MUE@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Patatin-like phospholipase - - - - - - - - - - - - Patatin CMS1_k127_5938614_0 1211115.ALIQ01000196_gene52 1.543e-184 580.0 COG1164@1|root,COG1164@2|Bacteria,1MXAC@1224|Proteobacteria,2TRPY@28211|Alphaproteobacteria,3NAKG@45404|Beijerinckiaceae 28211|Alphaproteobacteria E Oligopeptidase F pepF - - ko:K08602 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3,Peptidase_M3_N CMS1_k127_5964608_2 1123267.JONN01000001_gene992 2.541e-81 276.0 COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,2TQZ6@28211|Alphaproteobacteria,2K20D@204457|Sphingomonadales 204457|Sphingomonadales EQ PFAM Hydantoinase oxoprolinase - - 3.5.2.14 ko:K01473 ko00330,ko01100,map00330,map01100 - R03187 RC00632 ko00000,ko00001,ko01000 - - - Hydant_A_N,Hydantoinase_A CMS1_k127_5964608_0 1123267.JONN01000001_gene993 0.0 1046.0 COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,2TVYU@28211|Alphaproteobacteria,2K11U@204457|Sphingomonadales 204457|Sphingomonadales EQ PFAM Hydantoinase B oxoprolinase - - 3.5.2.14 ko:K01474 ko00330,ko01100,map00330,map01100 - R03187 RC00632 ko00000,ko00001,ko01000 - - - Hydantoinase_B CMS1_k127_5964608_1 1479239.JQMU01000001_gene1578 3.787e-206 654.0 COG1053@1|root,COG1053@2|Bacteria,1MURY@1224|Proteobacteria,2TUZ7@28211|Alphaproteobacteria,2KD4G@204457|Sphingomonadales 204457|Sphingomonadales C FAD binding domain - - 1.3.99.4 ko:K05898 ko00984,ko01100,ko01120,map00984,map01100,map01120 - R09884 RC00991 ko00000,ko00001,ko01000 - - - FAD_binding_2 CMS1_k127_5964608_3 1042375.AFPL01000045_gene1092 1.592e-22 100.0 COG1028@1|root,COG1028@2|Bacteria,1MUFX@1224|Proteobacteria,1RSP4@1236|Gammaproteobacteria,469S4@72275|Alteromonadaceae 1236|Gammaproteobacteria IQ KR domain hdhA GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008202,GO:0008206,GO:0008709,GO:0009056,GO:0009987,GO:0016043,GO:0016054,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022607,GO:0030573,GO:0032787,GO:0033764,GO:0042802,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072329,GO:1901360,GO:1901575,GO:1901615 1.1.1.159 ko:K00076 ko00121,map00121 - - - ko00000,ko00001,ko01000 - - - adh_short,adh_short_C2 CMS1_k127_5979381_0 1037409.BJ6T_87860 4.952e-142 453.0 COG3293@1|root,COG3293@2|Bacteria,1P5HD@1224|Proteobacteria,2TUQI@28211|Alphaproteobacteria,3JYMC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L Transposase DDE domain - - - - - - - - - - - - DDE_Tnp_1_2,DUF4096 CMS1_k127_5979381_3 1298858.AUEL01000007_gene2472 1.098e-72 254.0 COG0500@1|root,COG2226@2|Bacteria,1RJPA@1224|Proteobacteria,2TZCG@28211|Alphaproteobacteria,43P48@69277|Phyllobacteriaceae 28211|Alphaproteobacteria Q Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - - - - - - - - - - Methyltransf_31 CMS1_k127_5979381_4 1038866.KB902781_gene4259 8.928e-31 131.0 COG0515@1|root,COG0515@2|Bacteria,1PZU7@1224|Proteobacteria,2UZJM@28211|Alphaproteobacteria,3JYUY@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria KLT serine threonine protein kinase - - - - - - - - - - - - - CMS1_k127_5979381_5 595536.ADVE02000001_gene868 8.471e-18 93.0 COG4249@1|root,COG4249@2|Bacteria,1MX7B@1224|Proteobacteria,2TUDI@28211|Alphaproteobacteria,36YT7@31993|Methylocystaceae 28211|Alphaproteobacteria M Caspase domain MA20_30665 - - - - - - - - - - - Peptidase_C14 CMS1_k127_5979381_1 864051.BurJ1DRAFT_2708 9.02e-140 455.0 COG2124@1|root,COG2124@2|Bacteria,1MY5H@1224|Proteobacteria,2VPD5@28216|Betaproteobacteria,1KKCT@119065|unclassified Burkholderiales 28216|Betaproteobacteria C cytochrome P450 - - - - - - - - - - - - p450 CMS1_k127_5979381_2 1380355.JNIJ01000011_gene874 1.818e-96 324.0 COG3971@1|root,COG3971@2|Bacteria,1RGHI@1224|Proteobacteria,2V4BI@28211|Alphaproteobacteria,3JW69@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria Q 2-keto-4-pentenoate hydratase - - - - - - - - - - - - FAA_hydrolase CMS1_k127_6038238_2 1121106.JQKB01000020_gene2014 8.351e-111 370.0 COG0673@1|root,COG0673@2|Bacteria,1PYTN@1224|Proteobacteria,2TS0G@28211|Alphaproteobacteria,2JUXJ@204441|Rhodospirillales 204441|Rhodospirillales S Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA CMS1_k127_6038238_3 1298867.AUES01000017_gene3964 1.985e-67 238.0 COG4446@1|root,COG4446@2|Bacteria,1N31A@1224|Proteobacteria,2U0NZ@28211|Alphaproteobacteria,3JU37@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF1499) MA20_07395 - - - - - - - - - - - DUF1499 CMS1_k127_6038238_1 323097.Nham_0754 3.868e-137 441.0 COG0491@1|root,COG0491@2|Bacteria,1MVC3@1224|Proteobacteria,2TUAZ@28211|Alphaproteobacteria,3JRMU@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Metallo-beta-lactamase superfamily MA20_07390 - 3.1.2.6 ko:K01069 ko00620,map00620 - R01736 RC00004,RC00137 ko00000,ko00001,ko01000 - - - Lactamase_B CMS1_k127_6038238_4 114615.BRADO3920 3.214e-06 49.0 COG4953@1|root,COG4953@2|Bacteria,1MUA9@1224|Proteobacteria,2TR2R@28211|Alphaproteobacteria,3JS2X@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Penicillin-Binding Protein C-terminus Family pbpC - 2.4.1.129 ko:K05367 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - BiPBP_C,Transgly,Transpeptidase CMS1_k127_6038238_0 349163.Acry_2210 7.621e-196 618.0 COG0129@1|root,COG0129@2|Bacteria,1MV4I@1224|Proteobacteria,2TQRW@28211|Alphaproteobacteria,2JQ5K@204441|Rhodospirillales 204441|Rhodospirillales EG Belongs to the IlvD Edd family - - 4.2.1.82,4.2.1.9 ko:K01687,ko:K22186 ko00040,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00040,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R01209,R02429,R04441,R05070 RC00468,RC00543,RC01714 ko00000,ko00001,ko00002,ko01000 - - - ILVD_EDD CMS1_k127_6049398_8 1187851.A33M_2022 7.543e-104 345.0 COG0451@1|root,COG0451@2|Bacteria,1MWVJ@1224|Proteobacteria,2TRDY@28211|Alphaproteobacteria,3FD2R@34008|Rhodovulum 28211|Alphaproteobacteria GM COG0451 Nucleoside-diphosphate-sugar epimerases - - - - - - - - - - - - Epimerase CMS1_k127_6049398_2 113395.AXAI01000001_gene3018 1.477e-202 644.0 COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,2TQKQ@28211|Alphaproteobacteria,3JSS3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E GMC oxidoreductase MA20_44990 - 1.1.99.1 ko:K00108 ko00260,ko01100,map00260,map01100 M00555 R01025 RC00087 ko00000,ko00001,ko00002,ko01000 - - - GMC_oxred_C,GMC_oxred_N CMS1_k127_6049398_11 1430440.MGMSRv2_2090 2.389e-60 214.0 COG2143@1|root,COG2143@2|Bacteria,1QDKY@1224|Proteobacteria,2U1M5@28211|Alphaproteobacteria,2JX7F@204441|Rhodospirillales 204441|Rhodospirillales O Thioredoxin-like domain - - - - - - - - - - - - Thioredoxin_2 CMS1_k127_6049398_9 1430440.MGMSRv2_2000 5.705e-75 258.0 COG3005@1|root,COG3005@2|Bacteria,1MWV2@1224|Proteobacteria,2TURW@28211|Alphaproteobacteria,2JPFC@204441|Rhodospirillales 204441|Rhodospirillales C Cytochrome c-type protein - - - ko:K02569 - - - - ko00000 - - - Cytochrom_NNT CMS1_k127_6049398_3 85643.Tmz1t_4020 1.657e-174 558.0 COG0657@1|root,COG0657@2|Bacteria,1MV89@1224|Proteobacteria,2VJJC@28216|Betaproteobacteria,2M03F@206389|Rhodocyclales 206389|Rhodocyclales I Ethylbenzene dehydrogenase - - - - - - - - - - - - EB_dh CMS1_k127_6049398_6 1187851.A33M_0123 5.319e-155 503.0 COG3659@1|root,COG3659@2|Bacteria,1QMC3@1224|Proteobacteria,2TU5Q@28211|Alphaproteobacteria 28211|Alphaproteobacteria M PFAM Carbohydrate-selective porin OprB - - - ko:K07267 - - - - ko00000,ko02000 1.B.19.1 - - OprB CMS1_k127_6049398_10 1278309.KB907101_gene684 3.237e-61 219.0 COG2010@1|root,COG2010@2|Bacteria,1REKI@1224|Proteobacteria,1SQF5@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - Cytochrome_CBB3 CMS1_k127_6049398_1 622637.KE124774_gene3542 2.695e-248 771.0 COG3385@1|root,COG3385@2|Bacteria,1QURV@1224|Proteobacteria,2TW56@28211|Alphaproteobacteria,371IT@31993|Methylocystaceae 28211|Alphaproteobacteria L Transposase DDE domain group 1 - - - - - - - - - - - - DDE_Tnp_1_4 CMS1_k127_6049398_12 876269.ARWA01000001_gene8 1.334e-52 190.0 COG0517@1|root,COG0517@2|Bacteria,1N0H3@1224|Proteobacteria,2TX4N@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Domain in cystathionine beta-synthase and other proteins. - - - - - - - - - - - - CBS CMS1_k127_6049398_16 1211115.ALIQ01000053_gene2875 4.396e-45 172.0 COG0789@1|root,COG0789@2|Bacteria,1RGYB@1224|Proteobacteria,2U9A5@28211|Alphaproteobacteria,3NBE2@45404|Beijerinckiaceae 28211|Alphaproteobacteria K helix_turn_helix, mercury resistance merR - - - - - - - - - - - MerR_1 CMS1_k127_6049398_13 1197906.CAJQ02000010_gene3427 6.054e-52 185.0 COG0776@1|root,COG0776@2|Bacteria,1RH5Z@1224|Proteobacteria,2UCDG@28211|Alphaproteobacteria,3JYSB@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control himA - - ko:K04764 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding CMS1_k127_6049398_4 323097.Nham_1586 1.227e-163 537.0 COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,2TR60@28211|Alphaproteobacteria,3JR9U@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids fabH - 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C CMS1_k127_6049398_5 1429916.X566_21890 4.036e-159 508.0 COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,2TR53@28211|Alphaproteobacteria,3JU5X@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA plsX - 2.3.1.15 ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FA_synthesis CMS1_k127_6049398_15 189753.AXAS01000012_gene4231 1.735e-45 170.0 COG1399@1|root,COG1399@2|Bacteria,1N7C2@1224|Proteobacteria,2UC4J@28211|Alphaproteobacteria,3JTU8@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Uncharacterized ACR, COG1399 - - - ko:K07040 - - - - ko00000 - - - DUF177 CMS1_k127_6049398_17 709797.CSIRO_3285 1.556e-42 165.0 COG5452@1|root,COG5452@2|Bacteria,1N12T@1224|Proteobacteria,2UCES@28211|Alphaproteobacteria,3JRTC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Ubiquinol-cytochrome C chaperone - - - ko:K17662 - - - - ko00000,ko03029 - - - Ubiq_cyt_C_chap CMS1_k127_6049398_14 316058.RPB_2646 8.662e-52 190.0 COG2913@1|root,COG2913@2|Bacteria,1RHYM@1224|Proteobacteria,2UBU9@28211|Alphaproteobacteria,3JV18@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J SmpA / OmlA family MA20_36760 - - - - - - - - - - - SmpA_OmlA CMS1_k127_6049398_0 288000.BBta_4642 0.0 1128.0 COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,2TR9G@28211|Alphaproteobacteria,3JUCV@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force hppA - 3.6.1.1 ko:K15987 ko00190,map00190 - - - ko00000,ko00001,ko01000 3.A.10.1 - - H_PPase CMS1_k127_6049398_7 196490.AUEZ01000018_gene3392 7.508e-122 404.0 COG0477@1|root,COG2814@2|Bacteria,1MW59@1224|Proteobacteria,2TRA3@28211|Alphaproteobacteria,3JT8D@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria EGP Major Facilitator Superfamily MA20_22800 - - - - - - - - - - - MFS_1,Sugar_tr CMS1_k127_6055670_9 1096546.WYO_2033 5.008e-22 95.0 COG1657@1|root,COG1657@2|Bacteria,1MUIP@1224|Proteobacteria,2TRF3@28211|Alphaproteobacteria,1JR04@119045|Methylobacteriaceae 28211|Alphaproteobacteria I TIGRFAM squalene oxidosqualene cyclase shc - 4.2.1.129,5.4.99.17 ko:K06045 ko00909,ko01110,map00909,map01110 - R07322,R07323 RC01850,RC01851 ko00000,ko00001,ko01000 - - - SQHop_cyclase_C,SQHop_cyclase_N CMS1_k127_6055670_3 292.DM42_5245 1.037e-203 640.0 COG0535@1|root,COG0535@2|Bacteria,1MXM1@1224|Proteobacteria,2VNRX@28216|Betaproteobacteria,1K451@119060|Burkholderiaceae 28216|Betaproteobacteria S Hopanoid biosynthesis associated radical SAM protein HpnH hpnH - - - - - - - - - - - DUF3463,Fer4_14,Radical_SAM CMS1_k127_6055670_7 1223521.BBJX01000005_gene1936 1.075e-66 234.0 COG1305@1|root,COG1305@2|Bacteria,1R9XR@1224|Proteobacteria,2VIBI@28216|Betaproteobacteria,4AE08@80864|Comamonadaceae 28216|Betaproteobacteria E Transglutaminase-like superfamily - - - - - - - - - - - - Transglut_core CMS1_k127_6055670_6 1187851.A33M_3835 2.987e-77 274.0 COG3568@1|root,COG3568@2|Bacteria,1MVN7@1224|Proteobacteria,2V95R@28211|Alphaproteobacteria,3FEKE@34008|Rhodovulum 28211|Alphaproteobacteria L Endonuclease/Exonuclease/phosphatase family - - - - - - - - - - - - Exo_endo_phos CMS1_k127_6055670_2 1336208.JADY01000003_gene2786 2.14e-208 671.0 COG0398@1|root,COG1502@1|root,COG0398@2|Bacteria,COG1502@2|Bacteria,1MV8I@1224|Proteobacteria,2TTM4@28211|Alphaproteobacteria,2JPKW@204441|Rhodospirillales 204441|Rhodospirillales I Phospholipase D. Active site motifs. - - 3.1.4.4 ko:K01115 ko00564,ko00565,ko01100,ko01110,ko04014,ko04024,ko04071,ko04072,ko04144,ko04666,ko04724,ko04912,ko05231,map00564,map00565,map01100,map01110,map04014,map04024,map04071,map04072,map04144,map04666,map04724,map04912,map05231 - R01310,R02051,R07385 RC00017,RC00425 ko00000,ko00001,ko01000,ko04131 - - - PLDc,PLDc_2,SNARE_assoc CMS1_k127_6055670_8 1134912.AJTV01000026_gene2681 7.662e-41 154.0 COG0633@1|root,COG0633@2|Bacteria,1RHDC@1224|Proteobacteria,2U97J@28211|Alphaproteobacteria,36YN4@31993|Methylocystaceae 28211|Alphaproteobacteria C 2Fe-2S iron-sulfur cluster binding domain fdx - - ko:K04755 - - - - ko00000 - - - Fer2 CMS1_k127_6055670_4 196490.AUEZ01000015_gene4586 1.262e-180 570.0 COG0492@1|root,COG0492@2|Bacteria,1MW14@1224|Proteobacteria,2TSKU@28211|Alphaproteobacteria,3JTH2@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Ferredoxin--NADP reductase MA20_08170 - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Pyr_redox_3 CMS1_k127_6055670_5 1380394.JADL01000003_gene5179 1.07e-85 293.0 COG0703@1|root,COG1396@1|root,COG0703@2|Bacteria,COG1396@2|Bacteria,1MX66@1224|Proteobacteria,2TQWU@28211|Alphaproteobacteria,2JSJ6@204441|Rhodospirillales 204441|Rhodospirillales EK Shikimate kinase - - - - - - - - - - - - HTH_31,SKI CMS1_k127_6055670_1 1120983.KB894575_gene582 6.592e-237 744.0 COG1024@1|root,COG1024@2|Bacteria,1N817@1224|Proteobacteria,2TQTE@28211|Alphaproteobacteria 28211|Alphaproteobacteria I enoyl-CoA hydratase boxC - 4.1.2.44 ko:K15513 ko00362,map00362 - R09556 RC03426 ko00000,ko00001,ko01000 - - - ECH_1 CMS1_k127_6055670_0 1429916.X566_16520 7.723e-255 797.0 COG3396@1|root,COG3396@2|Bacteria,1MXUK@1224|Proteobacteria,2TTIG@28211|Alphaproteobacteria,3JSI1@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S benzoyl-CoA oxygenase boxB - 1.14.13.208 ko:K15512 ko00362,map00362 - R09555 RC01739 ko00000,ko00001,ko01000 - - - PaaA_PaaC CMS1_k127_6062050_6 709797.CSIRO_1664 9.055e-27 109.0 COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2TQPG@28211|Alphaproteobacteria,3JTQK@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Sigma-54 interaction domain flbD - - ko:K10943 ko02020,ko05111,map02020,map05111 M00515 - - ko00000,ko00001,ko00002,ko02022 - - - HTH_8,Response_reg,Sigma54_activat CMS1_k127_6062050_4 883080.HMPREF9697_02336 1.043e-46 170.0 COG3502@1|root,COG3502@2|Bacteria,1MZEQ@1224|Proteobacteria,2UBR3@28211|Alphaproteobacteria,3JZ4V@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF952) MA20_22095 - - - - - - - - - - - DUF952 CMS1_k127_6062050_8 1123355.JHYO01000012_gene666 1.933e-16 83.0 COG3181@1|root,COG3181@2|Bacteria,1MWVK@1224|Proteobacteria,2TXW7@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Tripartite tricarboxylate transporter family receptor - - - - - - - - - - - - TctC CMS1_k127_6062050_0 709797.CSIRO_4247 0.0 1041.0 COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,2TQUR@28211|Alphaproteobacteria,3JR3G@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin flhA - - ko:K02400 ko02040,map02040 - - - ko00000,ko00001,ko02035,ko02044 3.A.6.2,3.A.6.3 - - FHIPEP CMS1_k127_6062050_9 1429916.X566_14150 5.571e-16 81.0 2EF9R@1|root,3392M@2|Bacteria,1RHNG@1224|Proteobacteria,2U9B1@28211|Alphaproteobacteria,3JZD6@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - QU41_28935 - - - - - - - - - - - - CMS1_k127_6062050_3 1211115.ALIQ01000123_gene981 5.441e-78 264.0 COG2193@1|root,COG2193@2|Bacteria,1RCW7@1224|Proteobacteria,2U70I@28211|Alphaproteobacteria,3NAYG@45404|Beijerinckiaceae 28211|Alphaproteobacteria P Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex bfr - 1.16.3.1 ko:K03594 ko00860,map00860 - R00078 RC02758 ko00000,ko00001,ko01000 - - - Ferritin CMS1_k127_6062050_7 1211115.ALIQ01000123_gene980 2.104e-21 96.0 COG2906@1|root,COG2906@2|Bacteria,1PMPJ@1224|Proteobacteria,2V09F@28211|Alphaproteobacteria,3NBPM@45404|Beijerinckiaceae 28211|Alphaproteobacteria P BFD-like [2Fe-2S] binding domain - - - - - - - - - - - - Fer2_BFD CMS1_k127_6062050_10 652103.Rpdx1_3884 8.843e-07 53.0 2BP6F@1|root,32HXN@2|Bacteria,1N7T4@1224|Proteobacteria,2UFU3@28211|Alphaproteobacteria,3K1DA@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_6062050_1 316056.RPC_4405 2.253e-114 381.0 28NTG@1|root,2ZBS3@2|Bacteria,1N1KZ@1224|Proteobacteria,2TQM9@28211|Alphaproteobacteria,3JSKR@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - MA20_20990 - - - - - - - - - - - - CMS1_k127_6062050_2 1123229.AUBC01000003_gene2227 9.809e-87 306.0 COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,2TT0E@28211|Alphaproteobacteria,3JTSC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O Subtilase family - - - - - - - - - - - - Peptidase_S8 CMS1_k127_6062050_5 1123229.AUBC01000003_gene2224 3.231e-38 159.0 COG3468@1|root,COG5164@1|root,COG3468@2|Bacteria,COG5164@2|Bacteria 2|Bacteria K cell wall organization dnaX - 2.7.7.7,3.2.1.4 ko:K01179,ko:K02343 ko00230,ko00240,ko00500,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map00500,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378,R06200,R11307,R11308 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - GH5,GH9 - Autotransporter,Calx-beta,Collagen,HYR CMS1_k127_6062913_4 1502851.FG93_01288 5.135e-72 255.0 COG0438@1|root,COG0438@2|Bacteria,1MUTA@1224|Proteobacteria,2TSPN@28211|Alphaproteobacteria,3JYVS@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Glycosyl transferase 4-like capM - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 CMS1_k127_6062913_1 666684.AfiDRAFT_1616 1.102e-117 392.0 COG0028@1|root,COG0438@1|root,COG0028@2|Bacteria,COG0438@2|Bacteria,1MUTA@1224|Proteobacteria,2TSPN@28211|Alphaproteobacteria,3JYVS@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Glycosyl transferase 4-like capM - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 CMS1_k127_6062913_3 335659.S23_01310 1.12e-77 263.0 COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,2U58Z@28211|Alphaproteobacteria,3JTD0@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins infC GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - ko:K02520 - - - - ko00000,ko03012,ko03029 - - - IF3_C,IF3_N CMS1_k127_6062913_2 883080.HMPREF9697_00019 2.612e-84 292.0 2DBIF@1|root,2Z9FG@2|Bacteria,1QYR5@1224|Proteobacteria,2TTVX@28211|Alphaproteobacteria,3JXU6@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_6062913_6 1187851.A33M_3538 1.085e-32 129.0 COG0291@1|root,COG0291@2|Bacteria,1N6V4@1224|Proteobacteria,2UF6K@28211|Alphaproteobacteria,3FDGA@34008|Rhodovulum 28211|Alphaproteobacteria J Ribosomal protein L35 rpmI GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02916 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L35p CMS1_k127_6062913_5 1040989.AWZU01000069_gene3296 3.612e-57 205.0 COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,2U756@28211|Alphaproteobacteria,3JYPT@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit rplT GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0006996,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0065003,GO:0070925,GO:0071826,GO:0071840 - ko:K02887 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L20 CMS1_k127_6062913_0 1187851.A33M_3536 1.75e-204 639.0 COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,2TS2T@28211|Alphaproteobacteria,3FCRH@34008|Rhodovulum 28211|Alphaproteobacteria J tRNA synthetases class II core domain (F) pheS GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Phe_tRNA-synt_N,tRNA-synt_2d CMS1_k127_6063726_6 751994.AGIG01000017_gene55 1.359e-62 219.0 COG0457@1|root,COG0457@2|Bacteria,1QZ3D@1224|Proteobacteria 1224|Proteobacteria S Putative 2OG-Fe(II) oxygenase - - - - - - - - - - - - 2OG-FeII_Oxy_5 CMS1_k127_6063726_2 1187851.A33M_3448 3.795e-114 374.0 COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,2TSFJ@28211|Alphaproteobacteria,3FCYC@34008|Rhodovulum 28211|Alphaproteobacteria E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate dapB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000 - - - DapB_C,DapB_N CMS1_k127_6063726_8 909613.UO65_2497 1.753e-18 94.0 COG0500@1|root,COG2226@2|Bacteria,2HWAV@201174|Actinobacteria,4E23X@85010|Pseudonocardiales 201174|Actinobacteria Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_11 CMS1_k127_6063726_7 1126627.BAWE01000002_gene1113 2.736e-43 161.0 COG5470@1|root,COG5470@2|Bacteria,1N7JA@1224|Proteobacteria,2UBQW@28211|Alphaproteobacteria,3JZD7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Domain of unknown function (DUF1330) MA20_24570 - - - - - - - - - - - DUF1330 CMS1_k127_6063726_3 316055.RPE_0345 1.771e-93 312.0 COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,2TTB3@28211|Alphaproteobacteria,3JTIS@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) pyrF GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 ko:K01591 ko00240,ko01100,map00240,map01100 M00051 R00965 RC00409 ko00000,ko00001,ko00002,ko01000 - - - OMPdecase CMS1_k127_6063726_5 1187851.A33M_4148 2.28e-69 240.0 COG0431@1|root,COG0431@2|Bacteria,1RH7F@1224|Proteobacteria,2TUD4@28211|Alphaproteobacteria 28211|Alphaproteobacteria S NAD(P)H-dependent FMN reductase MA20_24580 - - - - - - - - - - - FMN_red CMS1_k127_6063726_4 1429916.X566_08785 5.394e-84 283.0 COG3963@1|root,COG3963@2|Bacteria,1N1KB@1224|Proteobacteria,2TVD9@28211|Alphaproteobacteria,3JRWY@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Ribosomal RNA adenine dimethylase pmtA - 2.1.1.17,2.1.1.71 ko:K00570 ko00564,ko01100,ko01110,map00564,map01100,map01110 M00091 R01320,R02056,R03424 RC00003,RC00060,RC00181,RC00496 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_25,RrnaAD CMS1_k127_6063726_1 323097.Nham_0156 5.232e-193 607.0 COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,2TRZ1@28211|Alphaproteobacteria,3JS0I@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins dnaJ - - ko:K03686 - - - - ko00000,ko03029,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG CMS1_k127_6063726_0 1429916.X566_08795 0.0 1119.0 COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,2TR5H@28211|Alphaproteobacteria,3JQXK@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O Heat shock 70 kDa protein dnaK - - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 CMS1_k127_6063726_9 323097.Nham_0154 2.237e-10 65.0 28JYF@1|root,2Z9NQ@2|Bacteria,1MXUQ@1224|Proteobacteria,2TS50@28211|Alphaproteobacteria,3JV8F@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - MA20_24600 - - - - - - - - - - - - CMS1_k127_6118303_5 1123277.KB893175_gene1447 5.68e-05 48.0 COG2244@1|root,COG2244@2|Bacteria,4NFKD@976|Bacteroidetes,47MS1@768503|Cytophagia 976|Bacteroidetes S Membrane protein involved in the export of O-antigen and teichoic acid wzxC - - ko:K03328,ko:K16695 - - - - ko00000,ko02000 2.A.66.2,2.A.66.2.7 - - Polysacc_synt_3,Polysacc_synt_C CMS1_k127_6118303_1 56110.Oscil6304_1711 2.105e-98 325.0 COG2227@1|root,COG2227@2|Bacteria,1GQ6N@1117|Cyanobacteria 1117|Cyanobacteria H Methyltransferase domain - - - - - - - - - - - - Methyltransf_11 CMS1_k127_6118303_0 56110.Oscil6304_1714 3.781e-192 606.0 COG0399@1|root,COG0399@2|Bacteria,1G4PM@1117|Cyanobacteria,1HFC1@1150|Oscillatoriales 1117|Cyanobacteria M PFAM DegT DnrJ EryC1 StrS aminotransferase family - - - - - - - - - - - - DegT_DnrJ_EryC1 CMS1_k127_6118303_3 523791.Kkor_0184 1.535e-39 170.0 COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,1MU3S@1224|Proteobacteria,1RNB8@1236|Gammaproteobacteria 1236|Gammaproteobacteria O Belongs to the peptidase S8 family - - - - - - - - - - - - PA,PKD,Peptidase_S8 CMS1_k127_6118303_4 1121935.AQXX01000140_gene1074 3.991e-13 83.0 COG3866@1|root,COG4733@1|root,COG5183@1|root,COG3866@2|Bacteria,COG4733@2|Bacteria,COG5183@2|Bacteria,1PS4F@1224|Proteobacteria,1RZWB@1236|Gammaproteobacteria,1XKNQ@135619|Oceanospirillales 135619|Oceanospirillales A Thrombospondin type 3 repeat - - - - - - - - - - - - TSP_3 CMS1_k127_6118303_2 102232.GLO73106DRAFT_00030410 2.512e-50 205.0 COG2931@1|root,COG2931@2|Bacteria,1GQPT@1117|Cyanobacteria 1117|Cyanobacteria Q calcium- and calmodulin-responsive adenylate cyclase activity - - - - - - - - - - - - Peptidase_S8 CMS1_k127_6151265_8 652103.Rpdx1_1160 8.888e-31 122.0 COG0500@1|root,COG0500@2|Bacteria,1RDRV@1224|Proteobacteria,2U70C@28211|Alphaproteobacteria,3K3VF@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_25,TPMT CMS1_k127_6151265_1 1187851.A33M_0118 2.856e-227 722.0 COG0433@1|root,COG0433@2|Bacteria,1MUSH@1224|Proteobacteria,2TUN9@28211|Alphaproteobacteria,3FEBN@34008|Rhodovulum 28211|Alphaproteobacteria S Domain of unknown function DUF87 MA20_26515 - - ko:K06915 - - - - ko00000 - - - DUF853,DUF87 CMS1_k127_6151265_5 316055.RPE_0393 4.206e-72 246.0 COG3786@1|root,COG3786@2|Bacteria,1RH22@1224|Proteobacteria,2U992@28211|Alphaproteobacteria,3JY74@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S L,D-transpeptidase catalytic domain - - - - - - - - - - - - YkuD CMS1_k127_6151265_3 1187851.A33M_1784 4.052e-122 400.0 COG0745@1|root,COG0745@2|Bacteria,1MU3A@1224|Proteobacteria,2TR97@28211|Alphaproteobacteria,3FCN1@34008|Rhodovulum 28211|Alphaproteobacteria K Transcriptional regulatory protein, C terminal mtrA - - - - - - - - - - - Response_reg,Trans_reg_C CMS1_k127_6151265_7 1187851.A33M_1783 2.565e-37 147.0 COG0664@1|root,COG0664@2|Bacteria,1RDKD@1224|Proteobacteria,2U76S@28211|Alphaproteobacteria 28211|Alphaproteobacteria T cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases MA20_24885 - - - - - - - - - - - cNMP_binding CMS1_k127_6151265_2 883078.HMPREF9695_04584 1.06e-127 412.0 COG0708@1|root,COG0708@2|Bacteria,1MVMC@1224|Proteobacteria,2TRWQ@28211|Alphaproteobacteria,3JQMZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L exodeoxyribonuclease III xthA2 - 3.1.11.2 ko:K01142 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Exo_endo_phos CMS1_k127_6151265_4 1297863.APJF01000006_gene1085 3.793e-80 276.0 COG2834@1|root,COG2834@2|Bacteria,1RA1S@1224|Proteobacteria,2U58W@28211|Alphaproteobacteria,3JR1T@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) lolA - - - - - - - - - - - LolA CMS1_k127_6151265_0 1380355.JNIJ01000027_gene788 0.0 1032.0 COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,2TR48@28211|Alphaproteobacteria,3JTM7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria D Ftsk_gamma ftsK - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma CMS1_k127_6151265_6 1297865.APJD01000019_gene3122 6.29e-58 203.0 COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,2TQVM@28211|Alphaproteobacteria,3JUEF@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Aminotransferase class I and II dapL - 2.6.1.17 ko:K14261,ko:K14267 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R04475 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 CMS1_k127_6185525_1 316056.RPC_0800 4.676e-79 266.0 COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,2TQKZ@28211|Alphaproteobacteria,3JQX8@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria N OmpA family MA20_18060 - - ko:K02557 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02000,ko02035 1.A.30.1 - - OmpA CMS1_k127_6185525_6 1287116.X734_24635 2.421e-31 124.0 2DNWH@1|root,32ZJ0@2|Bacteria,1NBJK@1224|Proteobacteria,2UKK3@28211|Alphaproteobacteria,43KQS@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF4031) - - - - - - - - - - - - DUF4031 CMS1_k127_6185525_2 196490.AUEZ01000009_gene5315 2.531e-60 212.0 COG0454@1|root,COG0456@2|Bacteria,1N3SK@1224|Proteobacteria,2UD71@28211|Alphaproteobacteria,3JYW9@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K Acetyltransferase (GNAT) domain MA20_18065 - - ko:K03827 - - - - ko00000,ko01000 - - - Acetyltransf_1,Acetyltransf_10 CMS1_k127_6185525_0 1304275.C41B8_04476 2.609e-140 461.0 COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,1RN70@1236|Gammaproteobacteria 1236|Gammaproteobacteria EGP Major facilitator superfamily yajR GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - - - - - - - - - - MFS_1,Sugar_tr CMS1_k127_6185525_5 1038862.KB893862_gene2525 1.061e-31 141.0 COG0254@1|root,COG0254@2|Bacteria,1MZ69@1224|Proteobacteria,2UBSC@28211|Alphaproteobacteria,3K03V@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J 50S ribosomal protein L31 rpmE - - ko:K02909 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L31 CMS1_k127_6185525_4 1187851.A33M_1492 3.149e-52 189.0 COG5317@1|root,COG5317@2|Bacteria,1RJIA@1224|Proteobacteria,2U9ID@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF1465) MA20_18080 - - ko:K13592 ko04112,map04112 - - - ko00000,ko00001 - - - DUF1465 CMS1_k127_6185525_7 316058.RPB_4493 3.363e-16 80.0 COG5509@1|root,COG5509@2|Bacteria,1NG8P@1224|Proteobacteria,2UJB2@28211|Alphaproteobacteria,3K0WS@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF1192) - - - - - - - - - - - - DUF1192 CMS1_k127_6185525_3 639283.Snov_3058 9.066e-53 190.0 COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,2TR1J@28211|Alphaproteobacteria,3EYMA@335928|Xanthobacteraceae 28211|Alphaproteobacteria C Zinc-binding dehydrogenase MA20_18095 - 1.6.5.5 ko:K00344 - - - - ko00000,ko01000 - - - ADH_N,ADH_zinc_N CMS1_k127_6200869_0 1298867.AUES01000068_gene3160 4.383e-234 728.0 COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,2TR3H@28211|Alphaproteobacteria,3JR8J@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA - - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C CMS1_k127_6200869_7 1082931.KKY_2436 2.51e-15 80.0 2EFVW@1|root,339N3@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - CMS1_k127_6200869_5 1197906.CAJQ02000026_gene3731 3.81e-71 243.0 COG4454@1|root,COG4454@2|Bacteria,1RF4H@1224|Proteobacteria,2U8UK@28211|Alphaproteobacteria,3JYXB@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_6200869_1 1429916.X566_03565 6.676e-177 562.0 COG0477@1|root,COG2814@2|Bacteria,1MV79@1224|Proteobacteria,2TX8S@28211|Alphaproteobacteria,3JSYQ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 CMS1_k127_6200869_4 311403.Arad_7219 1.114e-74 262.0 COG0715@1|root,COG0715@2|Bacteria,1Q5JF@1224|Proteobacteria,2VBX5@28211|Alphaproteobacteria,4BJ4H@82115|Rhizobiaceae 28211|Alphaproteobacteria P NMT1-like family - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 CMS1_k127_6200869_2 1437824.BN940_06921 2.881e-108 374.0 COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,2VMYS@28216|Betaproteobacteria,3T3UP@506|Alcaligenaceae 28216|Betaproteobacteria P ATPases associated with a variety of cellular activities - - - ko:K02049 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - ABC_tran CMS1_k127_6200869_3 1144310.PMI07_005440 6.946e-76 275.0 COG0600@1|root,COG0600@2|Bacteria,1Q2EA@1224|Proteobacteria,2UQF8@28211|Alphaproteobacteria,4BJE7@82115|Rhizobiaceae 28211|Alphaproteobacteria P Binding-protein-dependent transport system inner membrane component - - - - - - - - - - - - BPD_transp_1 CMS1_k127_6200869_6 1144310.PMI07_005439 1.258e-67 250.0 COG0600@1|root,COG0600@2|Bacteria,1PF1W@1224|Proteobacteria,2UQ2K@28211|Alphaproteobacteria,4BJDU@82115|Rhizobiaceae 28211|Alphaproteobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K02050 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - BPD_transp_1 CMS1_k127_620136_5 1411123.JQNH01000001_gene1866 2.649e-49 179.0 COG1234@1|root,COG1234@2|Bacteria,1Q4PW@1224|Proteobacteria,2TUHQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S PFAM beta-lactamase domain protein MA20_22080 - - - - - - - - - - - Lactamase_B_2 CMS1_k127_620136_3 1411123.JQNH01000001_gene1868 2.734e-83 281.0 COG0625@1|root,COG0625@2|Bacteria,1Q05U@1224|Proteobacteria,2U5IH@28211|Alphaproteobacteria 28211|Alphaproteobacteria O Glutathione S-transferase - - 2.5.1.18 ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 - R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905 RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944 ko00000,ko00001,ko01000,ko02000 1.A.12.2.2,1.A.12.3.2 - - GST_C,GST_C_2,GST_N,GST_N_3 CMS1_k127_620136_0 316058.RPB_3395 5.845e-230 722.0 COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2TUYS@28211|Alphaproteobacteria,3JRDP@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T His Kinase A (phosphoacceptor) domain MA20_25925 - 2.7.13.3 ko:K07716 ko02020,ko04112,map02020,map04112 M00511 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA CMS1_k127_620136_6 1449076.JOOE01000004_gene514 4.809e-13 71.0 COG3313@1|root,COG3313@2|Bacteria,1NGD5@1224|Proteobacteria,2VEI7@28211|Alphaproteobacteria,2K7XT@204457|Sphingomonadales 204457|Sphingomonadales S Protein of unknown function (DUF1289) - - - - - - - - - - - - DUF1289 CMS1_k127_620136_4 1187851.A33M_2808 1.264e-73 256.0 COG3577@1|root,COG3577@2|Bacteria,1MZCI@1224|Proteobacteria,2U9K2@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Aspartyl protease MA20_25915 - - ko:K06985 ko04112,map04112 - - - ko00000,ko00001 - - - Asp_protease_2,gag-asp_proteas CMS1_k127_620136_2 1187851.A33M_3033 1.18e-91 309.0 COG0730@1|root,COG0730@2|Bacteria,1R3V4@1224|Proteobacteria,2TRYX@28211|Alphaproteobacteria,3FD9G@34008|Rhodovulum 28211|Alphaproteobacteria S Sulfite exporter TauE/SafE MA20_43555 - - ko:K07090 - - - - ko00000 - - - TauE CMS1_k127_620136_1 1187851.A33M_3032 5.919e-146 469.0 COG0042@1|root,COG0042@2|Bacteria,1MUY1@1224|Proteobacteria,2TSRR@28211|Alphaproteobacteria,3FCSZ@34008|Rhodovulum 28211|Alphaproteobacteria J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs dusA - - ko:K05539 - - - - ko00000,ko01000,ko03016 - - - Dus CMS1_k127_680249_5 472175.EL18_01617 2.057e-42 160.0 COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,2TR7U@28211|Alphaproteobacteria,43II0@69277|Phyllobacteriaceae 28211|Alphaproteobacteria M Mechanosensitive ion channel mscS GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022607,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0042802,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0055082,GO:0055085,GO:0065003,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 - ko:K03442 - - - - ko00000,ko02000 1.A.23.2 - - MS_channel,TM_helix CMS1_k127_680249_1 709797.CSIRO_0535 5.556e-114 372.0 COG1011@1|root,COG1011@2|Bacteria,1PHPQ@1224|Proteobacteria,2TUDN@28211|Alphaproteobacteria,3JQW1@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Haloacid dehalogenase-like hydrolase MA20_21845 - - ko:K07025 - - - - ko00000 - - - HAD_2 CMS1_k127_680249_2 1187851.A33M_0260 1.073e-107 359.0 COG3409@1|root,COG5480@1|root,COG3409@2|Bacteria,COG5480@2|Bacteria,1P9ZA@1224|Proteobacteria,2TSTF@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Protein of unknown function (DUF1036) MA20_21840 - - - - - - - - - - - DUF1036,PG_binding_1 CMS1_k127_680249_0 323097.Nham_3700 8.526e-151 482.0 COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,2TQQS@28211|Alphaproteobacteria,3JVXI@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Belongs to the acetylglutamate kinase family. ArgB subfamily argB GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R02649 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase CMS1_k127_680249_6 1187851.A33M_0264 6.971e-30 122.0 COG2363@1|root,COG2363@2|Bacteria,1N966@1224|Proteobacteria,2UG11@28211|Alphaproteobacteria 28211|Alphaproteobacteria S small membrane protein MA20_21830 - - - - - - - - - - - DUF423 CMS1_k127_680249_4 1234364.AMSF01000015_gene3140 4.567e-69 240.0 COG3548@1|root,COG3548@2|Bacteria,1R9WQ@1224|Proteobacteria,1S2I3@1236|Gammaproteobacteria,1X6BV@135614|Xanthomonadales 135614|Xanthomonadales S integral membrane protein - - - - - - - - - - - - DUF1211 CMS1_k127_680249_3 1168059.KB899087_gene2664 2.349e-81 277.0 COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,2U5E5@28211|Alphaproteobacteria,3EY6Z@335928|Xanthobacteraceae 28211|Alphaproteobacteria D Necessary for normal cell division and for the maintenance of normal septation engB - - ko:K03978 - - - - ko00000,ko03036 - - - MMR_HSR1 CMS1_k127_69181_0 1336243.JAEA01000008_gene1092 1.21e-06 56.0 COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2USHR@28211|Alphaproteobacteria,1JU8Y@119045|Methylobacteriaceae 1224|Proteobacteria Q Haemolysin-type calcium-binding repeat (2 copies) - - - - - - - - - - - - Cadherin,HemolysinCabind,Peptidase_M10,Peptidase_M10_C CMS1_k127_69181_1 1282360.ABAC460_11175 0.0005947 49.0 28RXF@1|root,2ZE9I@2|Bacteria,1P8TY@1224|Proteobacteria 1224|Proteobacteria - - - - - - - - - - - - - - - CMS1_k127_696824_3 1187851.A33M_0948 5.962e-101 331.0 COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,2TR3N@28211|Alphaproteobacteria,3FCVV@34008|Rhodovulum 28211|Alphaproteobacteria J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS - 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1,zf-FPG_IleRS CMS1_k127_696824_1 319003.Bra1253DRAFT_03967 1.115e-112 372.0 COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,2TTUY@28211|Alphaproteobacteria,3JTDM@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H Belongs to the ribF family ribF - 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - FAD_syn,Flavokinase CMS1_k127_696824_5 709797.CSIRO_0257 9.467e-65 224.0 COG0745@1|root,COG0745@2|Bacteria,1RDNP@1224|Proteobacteria,2U7BP@28211|Alphaproteobacteria,3JY5W@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Response regulator receiver QU41_12045 - - ko:K03413 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - Response_reg CMS1_k127_696824_2 1187851.A33M_4474 2.109e-101 338.0 COG0647@1|root,COG0647@2|Bacteria,1MU9Y@1224|Proteobacteria,2TUH0@28211|Alphaproteobacteria,3FD18@34008|Rhodovulum 28211|Alphaproteobacteria G Haloacid dehalogenase-like hydrolase MA20_05625 - - - - - - - - - - - Hydrolase_6,Hydrolase_like CMS1_k127_696824_0 1297865.APJD01000009_gene2833 2.628e-138 452.0 COG2200@1|root,COG2200@2|Bacteria,1MU4F@1224|Proteobacteria,2TU9M@28211|Alphaproteobacteria,3JRX2@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Putative diguanylate phosphodiesterase MA20_05620 - - ko:K13593 ko04112,map04112 - - - ko00000,ko00001 - - - EAL CMS1_k127_696824_4 709797.CSIRO_3278 7.493e-91 314.0 COG1807@1|root,COG1807@2|Bacteria,1QA8B@1224|Proteobacteria,2TY1E@28211|Alphaproteobacteria,3K431@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - PMT_2 CMS1_k127_70074_2 706587.Desti_1170 2.626e-16 79.0 COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,42NBJ@68525|delta/epsilon subdivisions,2WJ52@28221|Deltaproteobacteria,2MQX1@213462|Syntrophobacterales 28221|Deltaproteobacteria O PFAM magnesium chelatase comM - - ko:K07391 - - - - ko00000 - - - ChlI,Mg_chelatase,Mg_chelatase_C CMS1_k127_70074_1 1163617.SCD_n02770 2.087e-32 132.0 COG3245@1|root,COG3245@2|Bacteria,1MZBZ@1224|Proteobacteria,2VSPR@28216|Betaproteobacteria 28216|Betaproteobacteria C cytochrome nosC - - - - - - - - - - - Cytochrome_CBB3 CMS1_k127_70074_0 1123020.AUIE01000024_gene5092 1.154e-43 162.0 COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RMFF@1236|Gammaproteobacteria,1YEQJ@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain lpdG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - iE2348C_1286.E2348C_4372,iJN746.PP_4187 Pyr_redox_2,Pyr_redox_dim CMS1_k127_70581_1 384765.SIAM614_04435 5.759e-59 221.0 COG0840@1|root,COG2972@1|root,COG0840@2|Bacteria,COG2972@2|Bacteria,1MU9B@1224|Proteobacteria,2TQR7@28211|Alphaproteobacteria 28211|Alphaproteobacteria T methyl-accepting chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal CMS1_k127_70581_0 395965.Msil_1780 2.332e-275 861.0 COG0529@1|root,COG2895@1|root,COG0529@2|Bacteria,COG2895@2|Bacteria,1MUD9@1224|Proteobacteria,2TQNJ@28211|Alphaproteobacteria,3NARA@45404|Beijerinckiaceae 28211|Alphaproteobacteria P Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily cysC - 2.7.1.25,2.7.7.4 ko:K00955 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176 R00509,R00529,R04928,R04929 RC00002,RC00078,RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - APS_kinase,GTP_EFTU CMS1_k127_70581_2 876269.ARWA01000001_gene1299 3.21e-56 197.0 COG0175@1|root,COG0175@2|Bacteria,1MUCZ@1224|Proteobacteria,2TT2D@28211|Alphaproteobacteria,3NACY@45404|Beijerinckiaceae 28211|Alphaproteobacteria EH Phosphoadenosine phosphosulfate reductase family cysD - 2.7.7.4 ko:K00957 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 M00176,M00596 R00529,R04929 RC02809,RC02889 ko00000,ko00001,ko00002,ko01000 - - - PAPS_reduct CMS1_k127_706274_1 935261.JAGL01000009_gene1222 3.542e-144 466.0 COG0683@1|root,COG0683@2|Bacteria,1MV3Y@1224|Proteobacteria,2TU2B@28211|Alphaproteobacteria,43HZY@69277|Phyllobacteriaceae 28211|Alphaproteobacteria E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component MA20_07775 - - ko:K01999,ko:K11959 ko02010,ko02024,map02010,map02024 M00237,M00323 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4,3.A.1.4.4,3.A.1.4.5 - - Peripla_BP_6 CMS1_k127_706274_0 1429916.X566_05980 1.258e-180 569.0 COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TR15@28211|Alphaproteobacteria,3JSF6@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Acyl-CoA dehydrogenase, C-terminal domain MA20_40160 - 1.3.8.7 ko:K00249 ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N CMS1_k127_7235_4 1429916.X566_21800 3.83e-52 187.0 COG1832@1|root,COG1832@2|Bacteria,1N03D@1224|Proteobacteria,2TUIY@28211|Alphaproteobacteria,3JQQK@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S CoA binding domain yccU GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K06929 - - - - ko00000 - - - CoA_binding_2 CMS1_k127_7235_0 1120983.KB894570_gene1325 2.374e-239 745.0 COG2873@1|root,COG2873@2|Bacteria,1NQME@1224|Proteobacteria,2TQW9@28211|Alphaproteobacteria,1JNK1@119043|Rhodobiaceae 28211|Alphaproteobacteria E Beta-eliminating lyase metY GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003961,GO:0004124,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006555,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0017144,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0050667,GO:0071265,GO:0071266,GO:0071268,GO:0071269,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47,2.5.1.49 ko:K01738,ko:K01740 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R01287,R03601,R04859 RC00020,RC02814,RC02821,RC02848 ko00000,ko00001,ko00002,ko01000 - - - Cys_Met_Meta_PP CMS1_k127_7235_2 1429916.X566_21810 9.875e-81 279.0 COG1024@1|root,COG1024@2|Bacteria,1RAAV@1224|Proteobacteria,2UB9Y@28211|Alphaproteobacteria,3JXKA@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Enoyl-CoA hydratase/isomerase - - 4.2.1.17 ko:K01692 ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212 M00032,M00087 R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093 RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 CMS1_k127_7235_1 316056.RPC_2687 4.033e-124 407.0 COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,2TR0M@28211|Alphaproteobacteria,3JR20@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group ctaA - - ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 M00154 R07412 RC00769 ko00000,ko00001,ko00002,ko03029 3.D.4.4 - - COX15-CtaA CMS1_k127_7235_5 709797.CSIRO_3227 2.34e-18 87.0 2EFTF@1|root,339JI@2|Bacteria,1N78S@1224|Proteobacteria,2UG3X@28211|Alphaproteobacteria,3K0ZB@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF2842) MA20_36920 - - - - - - - - - - - DUF2842 CMS1_k127_7235_3 1187851.A33M_2431 4.144e-62 216.0 COG0726@1|root,COG0726@2|Bacteria,1MVKH@1224|Proteobacteria,2TTEI@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Polysaccharide deacetylase - - - - - - - - - - - - Polysacc_deac_1 CMS1_k127_745684_0 1168059.KB899087_gene384 6.162e-185 587.0 COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,2TQSN@28211|Alphaproteobacteria,3F146@335928|Xanthobacteraceae 28211|Alphaproteobacteria E Aminotransferase class-V - - 2.6.1.44,2.6.1.45,2.6.1.51 ko:K00830 ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 M00346,M00532 R00369,R00372,R00585,R00588 RC00006,RC00008,RC00018 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_5 CMS1_k127_745684_1 639283.Snov_2529 1.32e-89 299.0 COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2TSN5@28211|Alphaproteobacteria,3EY0Y@335928|Xanthobacteraceae 28211|Alphaproteobacteria C FAD linked oxidases, C-terminal domain MA20_43170 - - - - - - - - - - - CCG,FAD-oxidase_C,FAD_binding_4,Fer4_8 CMS1_k127_748160_2 1187851.A33M_4246 3.416e-227 712.0 COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,2TRZQ@28211|Alphaproteobacteria,3FCK0@34008|Rhodovulum 28211|Alphaproteobacteria L DHH family recJ GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008297,GO:0008409,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0035312,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0045145,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 CMS1_k127_748160_30 1131814.JAFO01000001_gene4182 4.059e-35 137.0 COG0640@1|root,COG0640@2|Bacteria,1N72Q@1224|Proteobacteria,2UFSY@28211|Alphaproteobacteria,3F03G@335928|Xanthobacteraceae 28211|Alphaproteobacteria K PFAM regulatory protein ArsR soxR GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - - - - - - - - - - HTH_5 CMS1_k127_748160_31 1547437.LL06_06085 6.173e-33 133.0 COG0526@1|root,COG0526@2|Bacteria,1MZH0@1224|Proteobacteria,2UCBJ@28211|Alphaproteobacteria,43KQY@69277|Phyllobacteriaceae 28211|Alphaproteobacteria CO Regulatory protein SoxS soxS - - - - - - - - - - - - CMS1_k127_748160_18 1381123.AYOD01000035_gene3511 8.852e-88 296.0 COG0785@1|root,COG0785@2|Bacteria,1RCP7@1224|Proteobacteria,2TSAI@28211|Alphaproteobacteria,43I3A@69277|Phyllobacteriaceae 28211|Alphaproteobacteria O Cytochrome C biogenesis protein transmembrane region soxV - - ko:K06196 - - - - ko00000,ko02000 5.A.1.2 - - DsbD CMS1_k127_748160_32 1187851.A33M_4451 1.06e-25 115.0 2EKHB@1|root,33E7C@2|Bacteria,1QWW5@1224|Proteobacteria,2U4YX@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_748160_22 224911.27351769 7.85e-73 253.0 COG2143@1|root,COG2143@2|Bacteria,1QDKY@1224|Proteobacteria,2U1M5@28211|Alphaproteobacteria,3JUSZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O Thioredoxin-like domain soxW - - - - - - - - - - - Thioredoxin_2 CMS1_k127_748160_34 883078.HMPREF9695_00878 3.032e-17 88.0 COG2863@1|root,COG2863@2|Bacteria,1ND1W@1224|Proteobacteria,2UHAH@28211|Alphaproteobacteria,3K1B0@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C cytochrome - - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 CMS1_k127_748160_5 1411123.JQNH01000001_gene588 1.777e-181 576.0 COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,2TT55@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Sulfide dehydrogenase soxF - 1.8.2.3,1.8.5.4 ko:K17218,ko:K17229 ko00920,ko01120,map00920,map01120 - R09499,R10152 RC03155 ko00000,ko00001,ko01000 - - - FCSD-flav_bind,Pyr_redox_2 CMS1_k127_748160_7 360910.BAV0612 1.153e-159 508.0 COG0715@1|root,COG0715@2|Bacteria,1PKQN@1224|Proteobacteria,2VMW1@28216|Betaproteobacteria,3T349@506|Alcaligenaceae 28216|Betaproteobacteria P 4,5-dihydroxyphthalate decarboxylase - - 4.1.1.55 ko:K04102 ko00624,ko01100,ko01120,map00624,map01100,map01120 M00623 R01635,R05375 RC00390 ko00000,ko00001,ko00002,ko01000 - - - NMT1 CMS1_k127_748160_33 1038858.AXBA01000067_gene1365 9.427e-23 110.0 COG0725@1|root,COG0725@2|Bacteria,1RCHM@1224|Proteobacteria,2VGBX@28211|Alphaproteobacteria,3F2CK@335928|Xanthobacteraceae 28211|Alphaproteobacteria P Bacterial extracellular solute-binding protein - - 5.3.3.7 ko:K02020,ko:K22003 ko00660,ko02010,map00660,map02010 M00189 R02244 RC00668 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.8 - - SBP_bac_11 CMS1_k127_748160_1 1380394.JADL01000001_gene3066 1.168e-241 761.0 COG0028@1|root,COG0028@2|Bacteria,1MX3Q@1224|Proteobacteria,2U2RW@28211|Alphaproteobacteria,2JQZD@204441|Rhodospirillales 204441|Rhodospirillales EH Thiamine pyrophosphate enzyme, central domain - - - - - - - - - - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N CMS1_k127_748160_6 1187851.A33M_0255 1.169e-167 536.0 COG2951@1|root,COG3409@1|root,COG2951@2|Bacteria,COG3409@2|Bacteria,1MUZ3@1224|Proteobacteria,2TRP0@28211|Alphaproteobacteria,3FCYQ@34008|Rhodovulum 28211|Alphaproteobacteria M Transglycosylase SLT domain mltB - - ko:K00786,ko:K08305 - - - - ko00000,ko01000,ko01011 - GH103 - PG_binding_1,SLT_2 CMS1_k127_748160_11 709797.CSIRO_3129 1.009e-134 453.0 COG0739@1|root,COG0739@2|Bacteria,1QGHU@1224|Proteobacteria,2TUF9@28211|Alphaproteobacteria,3JR95@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M COG0739 Membrane proteins related to metalloendopeptidases - - - - - - - - - - - - Peptidase_M23 CMS1_k127_748160_17 1336243.JAEA01000008_gene1112 1.32e-89 299.0 COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,2TUWE@28211|Alphaproteobacteria,1JRWY@119045|Methylobacteriaceae 28211|Alphaproteobacteria J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C CMS1_k127_748160_9 1449049.JONW01000002_gene2478 1.497e-152 490.0 COG2269@1|root,COG2269@2|Bacteria,1MU97@1224|Proteobacteria,2TRD4@28211|Alphaproteobacteria,2KG86@204458|Caulobacterales 204458|Caulobacterales J class II (D K and N) - - - ko:K04568 - - - - ko00000,ko01000,ko03012 - - - tRNA-synt_2 CMS1_k127_748160_10 1411123.JQNH01000001_gene1257 5.553e-146 473.0 COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,2TT31@28211|Alphaproteobacteria 28211|Alphaproteobacteria E lysine 2,3-aminomutase kamA - 5.4.3.2 ko:K01843 ko00310,map00310 - R00461 RC00303 ko00000,ko00001,ko01000 - - - Fer4_12,Fer4_14,LAM_C,Radical_SAM CMS1_k127_748160_20 1187851.A33M_0888 2.858e-78 264.0 COG0346@1|root,COG0346@2|Bacteria,1RCYX@1224|Proteobacteria,2U7A8@28211|Alphaproteobacteria,3FD78@34008|Rhodovulum 28211|Alphaproteobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily gloA GO:0003674,GO:0003824,GO:0004462,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016846,GO:0034641,GO:0043603,GO:0044237,GO:0051186,GO:0071704,GO:1901564 4.4.1.5 ko:K01759 ko00620,map00620 - R02530 RC00004,RC00740 ko00000,ko00001,ko01000 - - - Glyoxalase CMS1_k127_748160_12 1187851.A33M_0887 1.644e-120 391.0 COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,2TV1Q@28211|Alphaproteobacteria,3FEKK@34008|Rhodovulum 28211|Alphaproteobacteria K Belongs to the sirtuin family. Class MA20_30275 - - ko:K12410 - - - - ko00000,ko01000 - - - SIR2 CMS1_k127_748160_14 1187851.A33M_0886 1.619e-99 329.0 COG1278@1|root,COG1278@2|Bacteria,1RAUE@1224|Proteobacteria,2U0S7@28211|Alphaproteobacteria,3FDFH@34008|Rhodovulum 28211|Alphaproteobacteria K Cold shock protein domain cspB - - ko:K03704 - - - - ko00000,ko03000 - - - CSD CMS1_k127_748160_29 1038867.AXAY01000006_gene4103 3.372e-54 194.0 COG1430@1|root,COG1430@2|Bacteria,1MZBJ@1224|Proteobacteria,2UBSI@28211|Alphaproteobacteria,3JY6D@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Uncharacterized ACR, COG1430 - - - ko:K09005 - - - - ko00000 - - - DUF192 CMS1_k127_748160_35 1279017.AQYJ01000026_gene22 5.384e-06 49.0 2DU2E@1|root,33NN7@2|Bacteria,1P5P1@1224|Proteobacteria,1SV3F@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_748160_15 1187851.A33M_3295 1.564e-98 330.0 COG0596@1|root,COG0596@2|Bacteria,1MVVX@1224|Proteobacteria,2TT0S@28211|Alphaproteobacteria,3FD4I@34008|Rhodovulum 28211|Alphaproteobacteria S Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 CMS1_k127_748160_4 883078.HMPREF9695_02174 1.715e-197 642.0 COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,2TRDB@28211|Alphaproteobacteria,3JT9G@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Transglycosylase SLT domain slt - - ko:K08309 - - - - ko00000,ko01000,ko01011 - GH23 - SLT CMS1_k127_748160_8 224911.27353337 1.414e-158 511.0 COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,2TR5W@28211|Alphaproteobacteria,3JTVB@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) dapA GO:0003674,GO:0003824,GO:0006082,GO:0006090,GO:0008150,GO:0008152,GO:0008840,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044281,GO:0071704 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS CMS1_k127_748160_27 113395.AXAI01000004_gene4470 2.011e-59 209.0 COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,2U99Y@28211|Alphaproteobacteria,3JY5H@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell mscL GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - ko:K03282 - - - - ko00000,ko02000 1.A.22.1 - - MscL CMS1_k127_748160_23 113395.AXAI01000004_gene4469 8.496e-72 244.0 COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,2U71I@28211|Alphaproteobacteria,3JSGD@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene smpB - - ko:K03664 - - - - ko00000 - - - SmpB CMS1_k127_748160_19 1380394.JADL01000005_gene5416 3.916e-81 278.0 COG0693@1|root,COG0693@2|Bacteria,1N8N6@1224|Proteobacteria,2TT0U@28211|Alphaproteobacteria,2JRW6@204441|Rhodospirillales 204441|Rhodospirillales S DJ-1/PfpI family - - 4.2.1.103 ko:K18199 ko00930,map00930 - R05771 RC01467 ko00000,ko00001,ko01000,ko01002 - - - DJ-1_PfpI CMS1_k127_748160_24 1205680.CAKO01000002_gene2312 3.454e-69 239.0 COG2032@1|root,COG2032@2|Bacteria,1RGV4@1224|Proteobacteria,2UC22@28211|Alphaproteobacteria,2JTWE@204441|Rhodospirillales 204441|Rhodospirillales P Destroys radicals which are normally produced within the cells and which are toxic to biological systems - - 1.15.1.1 ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 - - - ko00000,ko00001,ko01000 - - - Sod_Cu CMS1_k127_748160_28 1131814.JAFO01000001_gene2891 2.725e-56 200.0 COG0346@1|root,COG0346@2|Bacteria,1RH3J@1224|Proteobacteria,2U9J3@28211|Alphaproteobacteria 28211|Alphaproteobacteria E glyoxalase bleomycin resistance protein dioxygenase - - - - - - - - - - - - Glyoxalase CMS1_k127_748160_21 316057.RPD_2643 1.336e-76 260.0 COG1225@1|root,COG1225@2|Bacteria,1MWJP@1224|Proteobacteria,2TSSW@28211|Alphaproteobacteria,3JTKD@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O Redoxin MA20_36550 - 1.11.1.15 ko:K03386 ko04214,map04214 - - - ko00000,ko00001,ko01000,ko04147 - - - Redoxin CMS1_k127_748160_3 1411123.JQNH01000001_gene838 7.593e-198 633.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria 28211|Alphaproteobacteria T Diguanylate cyclase - - - - - - - - - - - - EAL,GGDEF,HAMP,PAS_4,PAS_7 CMS1_k127_748160_16 1131814.JAFO01000001_gene2889 6.817e-92 306.0 COG1573@1|root,COG1573@2|Bacteria,1MW91@1224|Proteobacteria,2TSUP@28211|Alphaproteobacteria,3EYC0@335928|Xanthobacteraceae 28211|Alphaproteobacteria L Uracil DNA glycosylase superfamily ung - 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG CMS1_k127_748160_13 1187851.A33M_3289 1.035e-106 351.0 COG1432@1|root,COG1432@2|Bacteria,1MUAE@1224|Proteobacteria,2TU5M@28211|Alphaproteobacteria,3FCXN@34008|Rhodovulum 28211|Alphaproteobacteria S NYN domain MA20_36560 - - - - - - - - - - - NYN CMS1_k127_748160_26 316056.RPC_2634 1.068e-63 220.0 COG1758@1|root,COG1758@2|Bacteria,1N6TX@1224|Proteobacteria,2U9BQ@28211|Alphaproteobacteria,3JY0E@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits rpoZ - 2.7.7.6 ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb6 CMS1_k127_748160_0 1187851.A33M_3287 0.0 1173.0 COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,2TQNY@28211|Alphaproteobacteria,3FCSP@34008|Rhodovulum 28211|Alphaproteobacteria KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance spoT - 2.7.6.5,3.1.7.2 ko:K00951,ko:K01139 ko00230,map00230 - R00336,R00429 RC00002,RC00078 ko00000,ko00001,ko01000,ko03009 - - - ACT_4,HD_4,RelA_SpoT,TGS CMS1_k127_748160_25 1304877.KI519399_gene4799 8.49e-64 224.0 COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,2TTTF@28211|Alphaproteobacteria,3JSGR@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate pdxJ GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 ko:K03474 ko00750,ko01100,map00750,map01100 M00124 R05838 RC01476 ko00000,ko00001,ko00002,ko01000 - - - PdxJ CMS1_k127_751970_0 1144310.PMI07_000354 2.922e-154 504.0 COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TQMW@28211|Alphaproteobacteria,4B7Q0@82115|Rhizobiaceae 28211|Alphaproteobacteria C Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - 1.2.5.3 ko:K03520 - - R11168 RC02800 ko00000,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 CMS1_k127_758943_1 1187851.A33M_2718 2.347e-191 600.0 COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,2TQQ4@28211|Alphaproteobacteria,3FCVB@34008|Rhodovulum 28211|Alphaproteobacteria J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) proS GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b CMS1_k127_758943_0 883080.HMPREF9697_00573 3.228e-229 714.0 COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,2TRBX@28211|Alphaproteobacteria,3JUG9@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M lipoprotein releasing system, transmembrane protein, LolC E family lolC - - ko:K09808 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko02000 3.A.1.125 - - FtsX,MacB_PCD CMS1_k127_758943_2 1187851.A33M_2720 7.389e-105 346.0 COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,2TSBE@28211|Alphaproteobacteria,3FCYK@34008|Rhodovulum 28211|Alphaproteobacteria V Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner lolD GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006807,GO:0006810,GO:0008104,GO:0008150,GO:0008152,GO:0015031,GO:0015399,GO:0015405,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0022804,GO:0022857,GO:0031224,GO:0032991,GO:0033036,GO:0042157,GO:0042160,GO:0042623,GO:0042626,GO:0042886,GO:0042953,GO:0043170,GO:0043190,GO:0043492,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901564,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - ko:K09810 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.125 - - ABC_tran CMS1_k127_771879_5 1305735.JAFT01000005_gene2484 6.219e-05 47.0 COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2TRM1@28211|Alphaproteobacteria,2PCB3@252301|Oceanicola 28211|Alphaproteobacteria G Tripartite ATP-independent periplasmic transporter, DctM component - - - - - - - - - - - - DctM CMS1_k127_771879_4 1381123.AYOD01000013_gene2186 2.739e-32 132.0 COG4665@1|root,COG4665@2|Bacteria,1RBTR@1224|Proteobacteria,2U8RR@28211|Alphaproteobacteria,43KXS@69277|Phyllobacteriaceae 28211|Alphaproteobacteria Q Tripartite ATP-independent periplasmic transporters, DctQ component - - - - - - - - - - - - DctQ CMS1_k127_771879_2 1223521.BBJX01000019_gene587 7.261e-80 280.0 COG1638@1|root,COG1638@2|Bacteria,1MUJY@1224|Proteobacteria 1224|Proteobacteria G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - - - - - - - - - - DctP CMS1_k127_771879_0 1038860.AXAP01000069_gene8506 2.553e-307 955.0 COG1384@1|root,COG1384@2|Bacteria,1MV32@1224|Proteobacteria,2TQYH@28211|Alphaproteobacteria,3JU8P@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Belongs to the class-I aminoacyl-tRNA synthetase family lysS - 6.1.1.6 ko:K04566 ko00970,map00970 M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1f CMS1_k127_771879_1 765698.Mesci_6350 2.613e-128 416.0 COG0583@1|root,COG0583@2|Bacteria,1MWY0@1224|Proteobacteria,2TSD9@28211|Alphaproteobacteria,43P6A@69277|Phyllobacteriaceae 28211|Alphaproteobacteria K LysR substrate binding domain - - - ko:K03566 ko02026,map02026 - - - ko00000,ko00001,ko03000 - - - HTH_1,LysR_substrate CMS1_k127_771879_3 631362.Thi970DRAFT_03258 6.727e-61 220.0 COG1297@1|root,COG1297@2|Bacteria,1N7SK@1224|Proteobacteria,1RNC8@1236|Gammaproteobacteria,1WXBI@135613|Chromatiales 135613|Chromatiales S oligopeptide transporter - - - - - - - - - - - - OPT CMS1_k127_807861_4 288000.BBta_1586 8.576e-14 70.0 COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,2TS6R@28211|Alphaproteobacteria,3JYC0@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmI - 5.4.2.12 ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 - - - Metalloenzyme,Phosphodiest,iPGM_N CMS1_k127_807861_3 716928.AJQT01000087_gene5014 3.342e-27 117.0 COG3103@1|root,COG4991@2|Bacteria,1RDIS@1224|Proteobacteria,2U9WQ@28211|Alphaproteobacteria,4BN07@82115|Rhizobiaceae 28211|Alphaproteobacteria T Protein of unknown function (DUF1236) - - - - - - - - - - - - DUF1236 CMS1_k127_807861_0 1187851.A33M_3716 1.792e-137 443.0 COG0350@1|root,COG2207@1|root,COG0350@2|Bacteria,COG2207@2|Bacteria,1N2YQ@1224|Proteobacteria,2TQRX@28211|Alphaproteobacteria,3FD2Z@34008|Rhodovulum 28211|Alphaproteobacteria K 6-O-methylguanine DNA methyltransferase, DNA binding domain ada - 2.1.1.63 ko:K10778 - - - - ko00000,ko01000,ko03000,ko03400 - - - DNA_binding_1,HTH_18 CMS1_k127_807861_2 1429916.X566_08735 7.128e-60 219.0 COG5488@1|root,COG5488@2|Bacteria,1NPQQ@1224|Proteobacteria,2UB81@28211|Alphaproteobacteria,3JRPQ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Integral membrane protein (DUF2244) - - - - - - - - - - - - DUF2244 CMS1_k127_807861_1 1187851.A33M_3714 5.629e-87 302.0 COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,2TRI2@28211|Alphaproteobacteria,3FCXK@34008|Rhodovulum 28211|Alphaproteobacteria L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate nth - 4.2.99.18 ko:K10773 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD CMS1_k127_808339_8 1297863.APJF01000006_gene1163 1.253e-40 154.0 COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria,2TQMD@28211|Alphaproteobacteria,3JRP1@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria GM NmrA-like family MA20_24380 - 1.6.5.3,1.6.99.3 ko:K00329,ko:K00356 ko00190,map00190 - R11945 RC00061 ko00000,ko00001,ko01000 - - - 3Beta_HSD,Epimerase,NAD_binding_10,RmlD_sub_bind CMS1_k127_808339_2 258594.RPA0046 1.47e-101 333.0 COG0349@1|root,COG0349@2|Bacteria,1MWFD@1224|Proteobacteria,2TQXS@28211|Alphaproteobacteria,3JRA3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L 3'-5' exonuclease rnd1 - 3.1.13.5 ko:K03684 - - - - ko00000,ko01000,ko03016 - - - DNA_pol_A_exo1 CMS1_k127_808339_7 1298867.AUES01000028_gene2602 8.252e-58 210.0 COG5375@1|root,COG5375@2|Bacteria,1R4YG@1224|Proteobacteria,2TUTA@28211|Alphaproteobacteria,3JRFN@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Lipopolysaccharide-assembly, LptC-related - - - ko:K11719 - - - - ko00000,ko02000 1.B.42.1 - - LptC CMS1_k127_808339_6 1197906.CAJQ02000029_gene3931 2.237e-61 218.0 COG1934@1|root,COG1934@2|Bacteria,1MXGA@1224|Proteobacteria,2U6DD@28211|Alphaproteobacteria,3JTRX@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S OstA-like protein lptA - - ko:K09774 - - - - ko00000,ko02000 1.B.42.1 - - OstA CMS1_k127_808339_1 1187851.A33M_0578 2.365e-130 423.0 COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,2TR7F@28211|Alphaproteobacteria,3FCNX@34008|Rhodovulum 28211|Alphaproteobacteria S ATPases associated with a variety of cellular activities lptB - - ko:K06861 ko02010,map02010 M00320 - - ko00000,ko00001,ko00002,ko01000,ko02000 1.B.42.1 - - ABC_tran,BCA_ABC_TP_C CMS1_k127_808339_0 1187851.A33M_0577 1.176e-220 698.0 COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,2TS41@28211|Alphaproteobacteria,3FCXW@34008|Rhodovulum 28211|Alphaproteobacteria K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released rpoN - - ko:K03092 ko02020,ko05111,map02020,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma54_AID,Sigma54_CBD,Sigma54_DBD CMS1_k127_808339_10 1125973.JNLC01000010_gene1108 4.047e-32 128.0 COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,2TV3J@28211|Alphaproteobacteria,3JRKU@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase hpf GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - ko:K05808 - - - - ko00000,ko03009 - - - Ribosom_S30AE_C,Ribosomal_S30AE CMS1_k127_808339_5 1380355.JNIJ01000038_gene4894 3.474e-68 243.0 COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,2U7B0@28211|Alphaproteobacteria,3JT8F@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria GT PTS IIA-like nitrogen-regulatory protein PtsN ptsN GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044424,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563 - ko:K02806 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 - - - PTS_EIIA_2 CMS1_k127_808339_9 1187851.A33M_3791 2.786e-33 130.0 COG5568@1|root,COG5568@2|Bacteria,1N9BT@1224|Proteobacteria,2UFNF@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF1150) MA20_24245 - - - - - - - - - - - DUF1150 CMS1_k127_808339_4 1429916.X566_08590 8.301e-73 248.0 COG0071@1|root,COG0071@2|Bacteria,1R9Y1@1224|Proteobacteria,2UA1J@28211|Alphaproteobacteria,3JT6X@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O Belongs to the small heat shock protein (HSP20) family hspH - - ko:K04080 - - - - ko00000,ko03110 - - - HSP20 CMS1_k127_808339_3 1463857.JOFZ01000012_gene2059 2.013e-93 317.0 COG4948@1|root,COG4948@2|Bacteria,2GKSK@201174|Actinobacteria 201174|Actinobacteria M mandelate racemase muconate lactonizing - - 5.1.2.2 ko:K01781 ko00627,ko01120,map00627,map01120 - R03791,R04161 RC00998 ko00000,ko00001,ko01000 - - - MR_MLE_C,MR_MLE_N CMS1_k127_83582_2 1121033.AUCF01000006_gene4313 7.832e-18 84.0 COG4137@1|root,COG4137@2|Bacteria,1PKET@1224|Proteobacteria,2U5RK@28211|Alphaproteobacteria,2JRWI@204441|Rhodospirillales 204441|Rhodospirillales S Cytochrome C assembly protein - - - - - - - - - - - - Cytochrom_C_asm CMS1_k127_83582_0 1380391.JIAS01000011_gene5052 5.716e-124 405.0 COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,2TRC8@28211|Alphaproteobacteria,2JP9I@204441|Rhodospirillales 204441|Rhodospirillales J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines dusB - - ko:K05540 - - - - ko00000,ko01000,ko03016 - - - Dus CMS1_k127_83582_1 414684.RC1_0128 2.095e-20 95.0 COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,2TQS1@28211|Alphaproteobacteria,2JQVX@204441|Rhodospirillales 204441|Rhodospirillales T Signal transduction histidine kinase, nitrogen specific ntrB - 2.7.13.3 ko:K07708 ko02020,map02020 M00497 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_4 CMS1_k127_85429_1 1125973.JNLC01000013_gene3870 5.621e-117 382.0 COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,2TRSK@28211|Alphaproteobacteria,3JRDF@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K transcriptional regulatory protein MA20_17930 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - Transcrip_reg CMS1_k127_85429_2 113395.AXAI01000033_gene631 3.902e-107 362.0 COG0654@1|root,COG0654@2|Bacteria,1QXV0@1224|Proteobacteria,2TWCX@28211|Alphaproteobacteria,3JZT4@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria CH FAD binding domain - - - - - - - - - - - - FAD_binding_3 CMS1_k127_85429_5 1168059.KB899087_gene4360 1.375e-55 204.0 COG0730@1|root,COG0730@2|Bacteria,1NAFA@1224|Proteobacteria,2U1B5@28211|Alphaproteobacteria,3F0GV@335928|Xanthobacteraceae 28211|Alphaproteobacteria S Sulfite exporter TauE/SafE MA20_24460 - - ko:K07090 - - - - ko00000 - - - TauE CMS1_k127_85429_4 1429916.X566_12535 5.223e-70 241.0 COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,2U70Z@28211|Alphaproteobacteria,3JSNW@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group ruvC GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 ko:K01159 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvC CMS1_k127_85429_3 1040989.AWZU01000006_gene567 1.1e-102 339.0 COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,2TSKM@28211|Alphaproteobacteria,3JS1W@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB ruvA GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 ko:K03550 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - HHH_5,RuvA_C,RuvA_N CMS1_k127_85429_0 316057.RPD_4167 4.306e-178 569.0 COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,2TQNG@28211|Alphaproteobacteria,3JRKW@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing ruvB GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 ko:K03551 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvB_C,RuvB_N CMS1_k127_85429_8 323097.Nham_0353 0.0002275 51.0 28NTG@1|root,2ZBS3@2|Bacteria,1N1KZ@1224|Proteobacteria,2TQM9@28211|Alphaproteobacteria,3JSKR@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - MA20_20990 - - - - - - - - - - - - CMS1_k127_862784_2 1038860.AXAP01000017_gene2909 2.695e-21 93.0 COG0683@1|root,COG0683@2|Bacteria,1MUNS@1224|Proteobacteria,2TTNM@28211|Alphaproteobacteria,3K61P@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Periplasmic binding protein domain - - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 CMS1_k127_862784_1 1038860.AXAP01000017_gene2910 6.654e-120 389.0 COG0411@1|root,COG0411@2|Bacteria,1MX51@1224|Proteobacteria,2TTG6@28211|Alphaproteobacteria,3JUVS@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - ko:K01995 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C CMS1_k127_862784_0 1038860.AXAP01000017_gene2911 1.036e-124 404.0 COG0410@1|root,COG0410@2|Bacteria,1P6Y7@1224|Proteobacteria,2VEYI@28211|Alphaproteobacteria,3K3VE@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E ATPases associated with a variety of cellular activities - - - ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran CMS1_k127_862784_3 1038860.AXAP01000017_gene2912 1.452e-16 90.0 COG0559@1|root,COG0559@2|Bacteria,1PHIJ@1224|Proteobacteria,2TUKF@28211|Alphaproteobacteria,3K45H@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Branched-chain amino acid transport system / permease component - - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 CMS1_k127_883176_2 1131814.JAFO01000001_gene1426 1.896e-43 162.0 COG1234@1|root,COG1234@2|Bacteria,1Q4PW@1224|Proteobacteria,2TUHQ@28211|Alphaproteobacteria 28211|Alphaproteobacteria S PFAM beta-lactamase domain protein MA20_22080 - - - - - - - - - - - Lactamase_B_2 CMS1_k127_883176_1 1298867.AUES01000015_gene3835 3.864e-143 460.0 COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,2TT50@28211|Alphaproteobacteria,3JS5I@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase MA20_25935 - 1.1.1.31,1.1.1.60 ko:K00020,ko:K00042 ko00280,ko00630,ko01100,map00280,map00630,map01100 - R01745,R01747,R05066 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 CMS1_k127_883176_0 1187851.A33M_2804 2.546e-165 527.0 COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,2TRDM@28211|Alphaproteobacteria,3FCMH@34008|Rhodovulum 28211|Alphaproteobacteria D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP mrp - - ko:K03593 - - - - ko00000,ko03029,ko03036 - - - FeS_assembly_P,ParA CMS1_k127_883176_3 991905.SL003B_0825 7.462e-13 70.0 COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,2TQNR@28211|Alphaproteobacteria,4BPV8@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria Q TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - - - - - - - - - - DctM CMS1_k127_891562_3 582899.Hden_1807 1.676e-86 305.0 COG0021@1|root,COG0021@2|Bacteria,1NXGM@1224|Proteobacteria,2U234@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate - - - - - - - - - - - - - CMS1_k127_891562_1 1380355.JNIJ01000028_gene723 4.953e-231 730.0 COG2114@1|root,COG2114@2|Bacteria,1MV1V@1224|Proteobacteria,2U2BQ@28211|Alphaproteobacteria,3JWN1@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T PFAM adenylyl cyclase class-3 4 guanylyl cyclase MA20_06330 - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - DUF3365,Guanylate_cyc CMS1_k127_891562_0 1187851.A33M_2418 1.787e-253 790.0 COG0143@1|root,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,2TQKA@28211|Alphaproteobacteria,3FD97@34008|Rhodovulum 28211|Alphaproteobacteria J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation metG - 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1g CMS1_k127_891562_2 172088.AUGA01000022_gene521 5.58e-119 395.0 COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,2TS88@28211|Alphaproteobacteria,3JTFT@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L TatD related DNase MA20_29410 - - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase CMS1_k127_891562_4 1187851.A33M_2243 5.892e-31 128.0 COG1235@1|root,COG1235@2|Bacteria,1MVJH@1224|Proteobacteria,2TQQN@28211|Alphaproteobacteria,3FCZQ@34008|Rhodovulum 28211|Alphaproteobacteria S Beta-lactamase superfamily domain phnP - 3.1.4.55 ko:K06167 ko00440,map00440 - R10205 RC00296 ko00000,ko00001,ko01000 - - - Lactamase_B_2 CMS1_k127_892959_0 1038859.AXAU01000006_gene5567 1.095e-74 269.0 COG0586@1|root,COG0586@2|Bacteria,1R5SJ@1224|Proteobacteria,2UG7E@28211|Alphaproteobacteria 28211|Alphaproteobacteria S membrane-associated protein - - - - - - - - - - - - SNARE_assoc CMS1_k127_892959_2 1510531.JQJJ01000009_gene981 3.073e-14 83.0 COG5640@1|root,COG5640@2|Bacteria,1NPS4@1224|Proteobacteria,2U4PS@28211|Alphaproteobacteria,3JTQ3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O Trypsin-like serine protease MA20_23090 - - - - - - - - - - - Trypsin CMS1_k127_892959_1 1187851.A33M_0397 1.675e-64 229.0 COG5640@1|root,COG5640@2|Bacteria 2|Bacteria O serine-type endopeptidase activity MA20_23090 - - - - - - - - - - - Trypsin CMS1_k127_912361_11 1123060.JONP01000024_gene2532 1.816e-66 239.0 COG2084@1|root,COG2084@2|Bacteria,1R7WF@1224|Proteobacteria,2U3AW@28211|Alphaproteobacteria 28211|Alphaproteobacteria I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - - - - - - - - - - NAD_binding_11,NAD_binding_2 CMS1_k127_912361_15 1123070.KB899262_gene1680 1.607e-48 177.0 COG1513@1|root,COG1513@2|Bacteria,46Z16@74201|Verrucomicrobia,2IVUF@203494|Verrucomicrobiae 203494|Verrucomicrobiae P Cyanate lyase C-terminal domain, Cyanate hydratase - - - - - - - - - - - - Cyanate_lyase CMS1_k127_912361_19 1500257.JQNM01000014_gene2931 7.265e-08 61.0 COG2180@1|root,COG2180@2|Bacteria,1NBVT@1224|Proteobacteria 1224|Proteobacteria C nitrate reductase molybdenum cofactor assembly chaperone - - - ko:K00373 ko02020,map02020 - - - ko00000,ko00001 - - - Nitrate_red_del CMS1_k127_912361_14 1205680.CAKO01000040_gene856 1.057e-51 197.0 COG2319@1|root,COG2319@2|Bacteria,1MV7S@1224|Proteobacteria,2TTNW@28211|Alphaproteobacteria,2JS73@204441|Rhodospirillales 204441|Rhodospirillales S WD40 repeats - - - - - - - - - - - - ANAPC4_WD40,WD40 CMS1_k127_912361_2 1550073.JROH01000052_gene3089 4.124e-132 434.0 COG0523@1|root,COG0523@2|Bacteria,1MVZV@1224|Proteobacteria,2TS4B@28211|Alphaproteobacteria,2K3UV@204457|Sphingomonadales 204457|Sphingomonadales S Cobalamin synthesis protein cobW C-terminal domain - - - - - - - - - - - - CobW_C,cobW CMS1_k127_912361_16 1245471.PCA10_06580 5.388e-39 154.0 COG5446@1|root,COG5446@2|Bacteria,1RBWQ@1224|Proteobacteria,1S72H@1236|Gammaproteobacteria,1YEW8@136841|Pseudomonas aeruginosa group 1236|Gammaproteobacteria S Probable cobalt transporter subunit (CbtA) cbtA - - - - - - - - - - - CbtA CMS1_k127_912361_20 205918.Psyr_3017 1.064e-06 52.0 2EKSU@1|root,33EGJ@2|Bacteria,1NGQH@1224|Proteobacteria,1ST4J@1236|Gammaproteobacteria,1Z8A7@136849|Pseudomonas syringae group 1236|Gammaproteobacteria S Probable cobalt transporter subunit (CbtB) cbtB - - - - - - - - - - - CbtB CMS1_k127_912361_4 1207063.P24_03915 2.514e-129 419.0 COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,2TUIC@28211|Alphaproteobacteria,2JQGG@204441|Rhodospirillales 204441|Rhodospirillales P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component - - - ko:K15578 ko00910,ko02010,map00910,map02010 M00438 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.16.1 - - ABC_tran CMS1_k127_912361_3 113395.AXAI01000011_gene6620 5.742e-130 419.0 COG0600@1|root,COG0600@2|Bacteria,1MU6Q@1224|Proteobacteria,2TQT6@28211|Alphaproteobacteria,3JQVS@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P nitrate ABC transporter nrtB - - ko:K02050,ko:K15577 ko00910,ko02010,map00910,map02010 M00188,M00438 - - ko00000,ko00001,ko00002,ko02000 3.A.1.16,3.A.1.16.1,3.A.1.16.2,3.A.1.17 - - BPD_transp_1 CMS1_k127_912361_0 1479237.JMLY01000001_gene1675 1.268e-202 643.0 COG0715@1|root,COG0715@2|Bacteria,1MWDN@1224|Proteobacteria,1RPUP@1236|Gammaproteobacteria,465AR@72275|Alteromonadaceae 1236|Gammaproteobacteria P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components nrtA - - ko:K15576 ko00910,ko02010,map00910,map02010 M00438 - - ko00000,ko00001,ko00002,ko02000 3.A.1.16.1,3.A.1.16.2 - - NMT1_2 CMS1_k127_912361_17 1163617.SCD_n02259 8.845e-16 87.0 COG3707@1|root,COG3707@2|Bacteria,1MXDV@1224|Proteobacteria,2VSMR@28216|Betaproteobacteria 28216|Betaproteobacteria K response regulator nasT - - ko:K07183 - - - - ko00000,ko02022 - - - ANTAR,Response_reg CMS1_k127_912361_7 311403.Arad_7227 2.615e-105 347.0 COG0235@1|root,COG0235@2|Bacteria,1RB5Z@1224|Proteobacteria,2U0PK@28211|Alphaproteobacteria,4BJEH@82115|Rhizobiaceae 28211|Alphaproteobacteria G Class II Aldolase and Adducin N-terminal domain - - - - - - - - - - - - Aldolase_II CMS1_k127_912361_12 1336208.JADY01000020_gene3414 2.8e-64 229.0 COG0235@1|root,COG0235@2|Bacteria,1RB5Z@1224|Proteobacteria,2U0PK@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Class II aldolase - - - - - - - - - - - - Aldolase_II CMS1_k127_912361_13 388399.SSE37_00950 5.25e-59 216.0 COG2358@1|root,COG2358@2|Bacteria,1R8QD@1224|Proteobacteria,2U7M9@28211|Alphaproteobacteria 28211|Alphaproteobacteria S TRAP transporter solute receptor TAXI family protein - - - - - - - - - - - - NMT1_3 CMS1_k127_912361_1 290400.Jann_3796 6.778e-184 595.0 COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,2TQY9@28211|Alphaproteobacteria 28211|Alphaproteobacteria S transport system fused permease components - - - - - - - - - - - - DctM CMS1_k127_912361_10 1120983.KB894572_gene2925 1.006e-73 258.0 COG1028@1|root,COG1028@2|Bacteria,1MX6D@1224|Proteobacteria,2TV8J@28211|Alphaproteobacteria 28211|Alphaproteobacteria IQ Short-chain dehydrogenase reductase sdr - - - - - - - - - - - - adh_short_C2 CMS1_k127_912361_8 246969.TAM4_600 2.229e-96 331.0 COG3839@1|root,arCOG00177@2157|Archaea,2XTU1@28890|Euryarchaeota 28890|Euryarchaeota E COG3842 ABC-type spermidine putrescine transport systems, ATPase components - - 3.6.3.29,3.6.3.30,3.6.3.55 ko:K02010,ko:K02017,ko:K15497 ko02010,map02010 M00189,M00190,M00423 R10531 RC00002 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10,3.A.1.6.5,3.A.1.8 - - ABC_tran,TOBE,TOBE_2 CMS1_k127_912361_9 246969.TAM4_600 8.963e-93 317.0 COG3839@1|root,arCOG00177@2157|Archaea,2XTU1@28890|Euryarchaeota 28890|Euryarchaeota E COG3842 ABC-type spermidine putrescine transport systems, ATPase components - - 3.6.3.29,3.6.3.30,3.6.3.55 ko:K02010,ko:K02017,ko:K15497 ko02010,map02010 M00189,M00190,M00423 R10531 RC00002 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10,3.A.1.6.5,3.A.1.8 - - ABC_tran,TOBE,TOBE_2 CMS1_k127_912361_6 1120983.KB894572_gene2920 2.415e-118 403.0 COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,2TVQS@28211|Alphaproteobacteria,1JQ5J@119043|Rhodobiaceae 28211|Alphaproteobacteria P Binding-protein-dependent transport system inner membrane component - - - ko:K02011 ko02010,map02010 M00190 - - ko00000,ko00001,ko00002,ko02000 3.A.1.10 - - BPD_transp_1 CMS1_k127_912361_18 935840.JAEQ01000020_gene2339 3.351e-11 75.0 COG1840@1|root,COG1840@2|Bacteria,1MXZ8@1224|Proteobacteria,2V7D9@28211|Alphaproteobacteria,43KPE@69277|Phyllobacteriaceae 28211|Alphaproteobacteria P Bacterial extracellular solute-binding protein - - - - - - - - - - - - SBP_bac_6 CMS1_k127_912361_5 1380391.JIAS01000018_gene1049 2.588e-120 394.0 COG0473@1|root,COG0473@2|Bacteria,1QU2H@1224|Proteobacteria,2VFXG@28211|Alphaproteobacteria,2JRH8@204441|Rhodospirillales 204441|Rhodospirillales CE Isocitrate/isopropylmalate dehydrogenase - - 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh CMS1_k127_918103_3 316058.RPB_3780 2.845e-58 221.0 COG0457@1|root,COG0457@2|Bacteria,1N09H@1224|Proteobacteria,2TSKT@28211|Alphaproteobacteria,3JS1S@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - - CMS1_k127_918103_4 323097.Nham_1388 5.018e-56 207.0 COG3334@1|root,COG3334@2|Bacteria,1RKF6@1224|Proteobacteria,2TRR1@28211|Alphaproteobacteria,3JTXB@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S PFAM MgtE intracellular MA20_08460 - - - - - - - - - - - MgtE_N CMS1_k127_918103_7 323097.Nham_1387 6.673e-30 124.0 2A6BI@1|root,30V4A@2|Bacteria,1RAJ5@1224|Proteobacteria,2U5D4@28211|Alphaproteobacteria,3JY0B@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - MA20_08455 - - - - - - - - - - - - CMS1_k127_918103_0 1187851.A33M_1055 2.285e-196 618.0 COG1868@1|root,COG1868@2|Bacteria,1MX01@1224|Proteobacteria,2TR4F@28211|Alphaproteobacteria 28211|Alphaproteobacteria N FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation fliM - - ko:K02416 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02035 - - - FliM,FliMN_C CMS1_k127_918103_5 1187851.A33M_1054 4.313e-55 199.0 COG1580@1|root,COG1580@2|Bacteria,1RH5D@1224|Proteobacteria,2U9BF@28211|Alphaproteobacteria,3FE9F@34008|Rhodovulum 28211|Alphaproteobacteria N Controls the rotational direction of flagella during chemotaxis fliL - - ko:K02415 - - - - ko00000,ko02035 - - - FliL CMS1_k127_918103_2 316056.RPC_1507 1.265e-89 304.0 COG4786@1|root,COG4786@2|Bacteria,1PZ24@1224|Proteobacteria,2U06G@28211|Alphaproteobacteria,3JR0D@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria N Belongs to the flagella basal body rod proteins family flgF - - ko:K02391,ko:K02392 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C CMS1_k127_918103_1 1429916.X566_24570 1.823e-128 414.0 COG4786@1|root,COG4786@2|Bacteria,1MVMA@1224|Proteobacteria,2TRR4@28211|Alphaproteobacteria,3JRIZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria N flagellar basal-body rod protein FlgG flgG - - ko:K02392 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - Flg_bb_rod,Flg_bbr_C CMS1_k127_918103_6 1187851.A33M_1051 8.46e-42 162.0 COG1261@1|root,COG1261@2|Bacteria,1PM4C@1224|Proteobacteria,2TRUS@28211|Alphaproteobacteria,3FDHW@34008|Rhodovulum 28211|Alphaproteobacteria N Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly flgA - - ko:K02386 ko02040,map02040 - - - ko00000,ko00001,ko02035 - - - ChapFlgA CMS1_k127_928795_6 652103.Rpdx1_0321 1.853e-22 102.0 COG2840@1|root,COG2840@2|Bacteria,1RH34@1224|Proteobacteria,2UCM1@28211|Alphaproteobacteria,3JWQZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Smr domain smrA - - - - - - - - - - - Smr CMS1_k127_928795_0 1125973.JNLC01000011_gene419 3.145e-100 343.0 COG2821@1|root,COG2821@2|Bacteria,1MXD4@1224|Proteobacteria,2TS5S@28211|Alphaproteobacteria,3JTB1@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M MltA specific insert domain mltA - - ko:K08304 - - - - ko00000,ko01000,ko01011 - GH102 - 3D,MltA CMS1_k127_928795_2 1038858.AXBA01000009_gene533 5.384e-92 308.0 COG4395@1|root,COG4395@2|Bacteria,1NCIX@1224|Proteobacteria,2TTDQ@28211|Alphaproteobacteria,3EXXB@335928|Xanthobacteraceae 28211|Alphaproteobacteria S import inner membrane translocase MA20_24770 - - - - - - - - - - - Tim44 CMS1_k127_928795_4 398525.KB900701_gene1568 2.078e-59 214.0 COG1952@1|root,COG1952@2|Bacteria,1RI75@1224|Proteobacteria,2UBTB@28211|Alphaproteobacteria,3JVEB@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria U One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA secB GO:0002790,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - ko:K03071 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03110 3.A.5 - - SecB CMS1_k127_928795_1 1126627.BAWE01000002_gene1158 4.878e-95 318.0 COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,2TTFF@28211|Alphaproteobacteria,3JR18@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease dnaQ - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_T CMS1_k127_928795_3 1380355.JNIJ01000027_gene767 3.6e-74 256.0 COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,2U765@28211|Alphaproteobacteria,3JQTC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A coaE GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - CoaE CMS1_k127_928795_5 1187851.A33M_0567 4.641e-39 147.0 COG0424@1|root,COG0424@2|Bacteria,1RDA9@1224|Proteobacteria,2U9H5@28211|Alphaproteobacteria,3FD8V@34008|Rhodovulum 28211|Alphaproteobacteria D Maf-like protein maf - - ko:K06287 - - - - ko00000 - - - Maf CMS1_k127_935745_1 323098.Nwi_1150 6.398e-221 695.0 COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,2TQQ8@28211|Alphaproteobacteria,3JR76@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M penicillin-binding protein pbp - 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase CMS1_k127_935745_4 1429916.X566_15710 2.093e-77 264.0 COG5402@1|root,COG5402@2|Bacteria,1N26C@1224|Proteobacteria,2TT9K@28211|Alphaproteobacteria,3JU6I@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF1214) MA20_15585 - - - - - - - - - - - DUF1214 CMS1_k127_935745_5 1187851.A33M_1520 4.056e-74 256.0 COG5436@1|root,COG5436@2|Bacteria,1MW0D@1224|Proteobacteria,2TU65@28211|Alphaproteobacteria 28211|Alphaproteobacteria S integral membrane protein MA20_15590 - - - - - - - - - - - DUF1254 CMS1_k127_935745_9 114615.BRADO2713 2.674e-55 204.0 2CVSH@1|root,32SY5@2|Bacteria,1MVP4@1224|Proteobacteria,2TTAG@28211|Alphaproteobacteria,3JQUT@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - MA20_15675 - - - - - - - - - - - - CMS1_k127_935745_17 335659.S23_49210 1.824e-06 53.0 2C35M@1|root,301N4@2|Bacteria,1N8YA@1224|Proteobacteria,2UFAA@28211|Alphaproteobacteria,3K1A0@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_935745_10 323097.Nham_1399 6.585e-48 183.0 COG5330@1|root,COG5330@2|Bacteria,1MUTG@1224|Proteobacteria,2U0SA@28211|Alphaproteobacteria,3JQV3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Uncharacterised protein conserved in bacteria (DUF2336) - - - - - - - - - - - - DUF2336 CMS1_k127_935745_11 1187851.A33M_3216 1.107e-42 159.0 COG5447@1|root,COG5447@2|Bacteria,1N1KU@1224|Proteobacteria,2UCBQ@28211|Alphaproteobacteria,3FDG1@34008|Rhodovulum 28211|Alphaproteobacteria S Protein of unknown function (DUF1491) MA20_15690 - - - - - - - - - - - DUF1491 CMS1_k127_935745_12 1187851.A33M_3217 2.118e-40 158.0 COG3409@1|root,COG3409@2|Bacteria,1NDAQ@1224|Proteobacteria,2UHRV@28211|Alphaproteobacteria 28211|Alphaproteobacteria M Putative peptidoglycan binding domain - - - - - - - - - - - - PG_binding_1 CMS1_k127_935745_0 1187851.A33M_3218 1.374e-226 716.0 COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2TSRP@28211|Alphaproteobacteria 28211|Alphaproteobacteria T Histidine kinase divJ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 ko:K07716,ko:K11357 ko02020,ko04112,map02020,map04112 M00511 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA,PAS,PAS_3,PAS_4 CMS1_k127_935745_16 323097.Nham_2624 1.761e-21 101.0 2E4C7@1|root,32Z7R@2|Bacteria,1RBPI@1224|Proteobacteria,2U5ZQ@28211|Alphaproteobacteria,3JY81@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Family of unknown function (DUF5330) - - - - - - - - - - - - DUF5330 CMS1_k127_935745_8 1125973.JNLC01000014_gene2582 3.16e-56 204.0 COG2166@1|root,COG2166@2|Bacteria,1RI8F@1224|Proteobacteria,2U9A2@28211|Alphaproteobacteria,3JY1C@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Fe-S metabolism associated domain sufE - - ko:K02426 - - - - ko00000 - - - SufE CMS1_k127_935745_6 652103.Rpdx1_3669 9.023e-69 240.0 COG0583@1|root,COG0583@2|Bacteria,1MXC9@1224|Proteobacteria,2TTTY@28211|Alphaproteobacteria,3JYJX@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids - - - - - - - - - - - - - CMS1_k127_935745_15 1120983.KB894571_gene2158 1.263e-23 104.0 COG0593@1|root,COG0593@2|Bacteria,1N76V@1224|Proteobacteria,2UG3R@28211|Alphaproteobacteria,1JPIR@119043|Rhodobiaceae 28211|Alphaproteobacteria L Bacterial dnaA protein helix-turn-helix - - - - - - - - - - - - Bac_DnaA_C CMS1_k127_935745_7 1187851.A33M_0482 1.568e-64 224.0 COG4957@1|root,COG4957@2|Bacteria,1RGUW@1224|Proteobacteria,2U99M@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Transcriptional regulator MA20_15715 - - - - - - - - - - - ROS_MUCR CMS1_k127_935745_13 936455.KI421499_gene4205 1.518e-28 126.0 2E7KS@1|root,3322S@2|Bacteria,1PBYA@1224|Proteobacteria,2U1J9@28211|Alphaproteobacteria,3JTUG@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_935745_3 1187851.A33M_0020 3.186e-112 366.0 COG0605@1|root,COG0605@2|Bacteria,1MVW2@1224|Proteobacteria,2TU3T@28211|Alphaproteobacteria,3FD1C@34008|Rhodovulum 28211|Alphaproteobacteria P Destroys radicals which are normally produced within the cells and which are toxic to biological systems sodB - 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 - - - ko00000,ko00001,ko01000 - - - Sod_Fe_C,Sod_Fe_N CMS1_k127_935745_14 1304878.AUGD01000003_gene2765 5.581e-24 109.0 2FDWH@1|root,345WZ@2|Bacteria,1RINP@1224|Proteobacteria,2UD49@28211|Alphaproteobacteria,3JZTN@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - MA20_23535 - - - - - - - - - - - - CMS1_k127_935745_2 1211115.ALIQ01000046_gene3036 3.916e-157 512.0 COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,2U0TP@28211|Alphaproteobacteria 28211|Alphaproteobacteria O NfeD-like C-terminal, partner-binding nfeD - - ko:K07403 - - - - ko00000 - - - NfeD CMS1_k127_937474_13 316057.RPD_0105 6.469e-100 328.0 COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,2TRGZ@28211|Alphaproteobacteria,3JQX4@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Carbon-nitrogen hydrolase MA20_39720 - - ko:K11206 - - - - ko00000,ko01000 - - - CN_hydrolase CMS1_k127_937474_20 1038860.AXAP01000016_gene2122 2.343e-55 200.0 COG5319@1|root,COG5319@2|Bacteria,1MZN2@1224|Proteobacteria,2UBTA@28211|Alphaproteobacteria,3JY8M@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF1178) MA20_39715 - - - - - - - - - - - DUF1178 CMS1_k127_937474_12 1187851.A33M_3562 5.312e-105 350.0 COG0697@1|root,COG0697@2|Bacteria,1PHRI@1224|Proteobacteria,2TUAQ@28211|Alphaproteobacteria,3FE7Z@34008|Rhodovulum 28211|Alphaproteobacteria EG EamA-like transporter family MA20_39710 - - - - - - - - - - - EamA CMS1_k127_937474_24 316055.RPE_2883 1.656e-11 70.0 COG2329@1|root,COG2329@2|Bacteria,1NDM8@1224|Proteobacteria,2UG48@28211|Alphaproteobacteria,3JYVV@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Putative mono-oxygenase ydhR - - - - - - - - - - - - ydhR CMS1_k127_937474_10 1187851.A33M_1516 2.08e-112 369.0 COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,2TRIK@28211|Alphaproteobacteria,3FCYS@34008|Rhodovulum 28211|Alphaproteobacteria J O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway ubiG - 2.1.1.222,2.1.1.64 ko:K00568 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04988,R05614,R08769,R08781 RC00003,RC00392,RC01895 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_11,Methyltransf_23 CMS1_k127_937474_4 1038859.AXAU01000001_gene3651 1.346e-182 577.0 COG4663@1|root,COG4663@2|Bacteria,1R40U@1224|Proteobacteria,2U3KB@28211|Alphaproteobacteria,3K34G@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria Q Bacterial extracellular solute-binding protein, family 7 - - - - - - - - - - - - DctP CMS1_k127_937474_16 1038859.AXAU01000001_gene3650 1.004e-82 280.0 COG4665@1|root,COG4665@2|Bacteria,1RHBW@1224|Proteobacteria,2UBPX@28211|Alphaproteobacteria,3K2R5@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria Q Tripartite ATP-independent periplasmic transporters, DctQ component - - - - - - - - - - - - DctQ CMS1_k127_937474_1 318996.AXAZ01000001_gene4882 8.195e-223 698.0 COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,2TQNR@28211|Alphaproteobacteria,3JTY7@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria Q Tripartite ATP-independent periplasmic transporter, DctM component - - - - - - - - - - - - DctM,DctQ CMS1_k127_937474_3 1040989.AWZU01000017_gene3233 1.01e-208 659.0 COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,2TRFA@28211|Alphaproteobacteria,3JUKJ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Belongs to the aspartokinase family lysC GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,ACT,ACT_7 CMS1_k127_937474_14 1028800.RG540_CH19420 5.601e-97 328.0 COG2159@1|root,COG2159@2|Bacteria,1MXI7@1224|Proteobacteria,2U15G@28211|Alphaproteobacteria,4B8SX@82115|Rhizobiaceae 28211|Alphaproteobacteria S Amidohydrolase - - 4.1.1.46 ko:K07045,ko:K14333,ko:K15063 ko00362,ko00627,ko01120,map00362,map00627,map01120 - R00821,R09278 RC00390 ko00000,ko00001,ko01000 - - - Amidohydro_2 CMS1_k127_937474_0 1187851.A33M_1513 0.0 1174.0 COG3605@1|root,COG3605@2|Bacteria,1QTTV@1224|Proteobacteria,2TR3Z@28211|Alphaproteobacteria,3FCUB@34008|Rhodovulum 28211|Alphaproteobacteria T PEP-utilising enzyme, N-terminal ptsP - 2.7.3.9 ko:K08484 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 - - - GAF,GAF_2,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C CMS1_k127_937474_6 666684.AfiDRAFT_1177 3.995e-160 518.0 COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,2TQSV@28211|Alphaproteobacteria,3JUZF@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA prfA - - ko:K02835 - - - - ko00000,ko03012 - - - PCRF,RF-1 CMS1_k127_937474_15 196490.AUEZ01000040_gene6021 1.372e-83 288.0 COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,2TZFK@28211|Alphaproteobacteria,3JUFB@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif prmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 ko:K02493 - - R10806 RC00003,RC03279 ko00000,ko01000,ko03012 - - - MTS,Methyltransf_31 CMS1_k127_937474_21 883080.HMPREF9697_03146 2.103e-48 184.0 COG5373@1|root,COG5373@2|Bacteria,1N7JV@1224|Proteobacteria,2TR7A@28211|Alphaproteobacteria,3JRVV@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Domain of unknown function (DUF4167) - - - - - - - - - - - - DUF4167 CMS1_k127_937474_9 1380355.JNIJ01000032_gene3436 1.159e-122 396.0 COG0500@1|root,COG2226@2|Bacteria,1NA7K@1224|Proteobacteria,2TT7T@28211|Alphaproteobacteria,3JT80@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria Q Methyltransferase domain MA20_39625 - - - - - - - - - - - Methyltransf_11 CMS1_k127_937474_11 1187851.A33M_1675 3.049e-112 367.0 COG0491@1|root,COG0491@2|Bacteria,1MU8Q@1224|Proteobacteria,2TSVS@28211|Alphaproteobacteria,3FCYJ@34008|Rhodovulum 28211|Alphaproteobacteria S Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid gloB - 3.1.2.6 ko:K01069 ko00620,map00620 - R01736 RC00004,RC00137 ko00000,ko00001,ko01000 - - - HAGH_C,Lactamase_B CMS1_k127_937474_18 709797.CSIRO_0679 1.795e-64 225.0 COG3542@1|root,COG3542@2|Bacteria,1RHBE@1224|Proteobacteria,2U962@28211|Alphaproteobacteria,3JYGA@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Cupin superfamily (DUF985) MA20_39615 - - ko:K09705 - - - - ko00000 - - - Cupin_5 CMS1_k127_937474_22 1528106.JRJE01000009_gene1787 6.329e-45 185.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2TQR7@28211|Alphaproteobacteria,2JPFH@204441|Rhodospirillales 204441|Rhodospirillales NT methyl-accepting chemotaxis protein - - - ko:K03406 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko02035 - - - HAMP,MCPsignal CMS1_k127_937474_23 492774.JQMB01000007_gene4091 3.576e-24 106.0 COG5591@1|root,COG5591@2|Bacteria,1N7YT@1224|Proteobacteria,2UAX7@28211|Alphaproteobacteria,4BKY2@82115|Rhizobiaceae 28211|Alphaproteobacteria S Peptidase propeptide and YPEB domain - - - - - - - - - - - - PepSY_2 CMS1_k127_937474_19 1120983.KB894573_gene125 7.919e-64 229.0 COG0235@1|root,COG0235@2|Bacteria,1RB5Z@1224|Proteobacteria,2U0PK@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Class II aldolase - GO:0003674,GO:0003824,GO:0005488,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009111,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0017144,GO:0030145,GO:0034641,GO:0042365,GO:0042737,GO:0042816,GO:0042820,GO:0043167,GO:0043169,GO:0044237,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0047431,GO:0071704,GO:0072524,GO:0072526,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 4.1.1.51 ko:K18613 ko00750,ko01120,map00750,map01120 - R03461 RC00569 ko00000,ko00001,ko01000 - - - Aldolase_II CMS1_k127_937474_8 114615.BRADO0563 1.193e-125 406.0 COG1028@1|root,COG1028@2|Bacteria,1MUEV@1224|Proteobacteria,2TRCF@28211|Alphaproteobacteria,3JQSI@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria IQ KR domain phbB - 1.1.1.36 ko:K00023 ko00630,ko00650,ko01120,ko01200,map00630,map00650,map01120,map01200 M00373 R01779,R01977 RC00103,RC00117 ko00000,ko00001,ko00002,ko01000 - - - adh_short_C2 CMS1_k127_937474_2 323098.Nwi_3060 2.282e-217 678.0 COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2TQQ7@28211|Alphaproteobacteria,3JRMV@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Belongs to the thiolase family phbA - 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Thiolase_C,Thiolase_N CMS1_k127_937474_17 1187851.A33M_1432 1.056e-75 260.0 COG5394@1|root,COG5394@2|Bacteria,1RHRC@1224|Proteobacteria,2TQWQ@28211|Alphaproteobacteria,3FDBQ@34008|Rhodovulum 28211|Alphaproteobacteria S PHB accumulation regulatory domain phaR - - - - - - - - - - - PHB_acc,PHB_acc_N CMS1_k127_937474_7 196367.JNFG01000214_gene1158 1.95e-148 492.0 COG0654@1|root,COG0654@2|Bacteria,1MUN4@1224|Proteobacteria,2VN4I@28216|Betaproteobacteria,1KH0M@119060|Burkholderiaceae 28216|Betaproteobacteria CH FAD binding domain - - - - - - - - - - - - FAD_binding_3 CMS1_k127_937474_5 1187851.A33M_1431 5.887e-174 554.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2UP6H@28211|Alphaproteobacteria 28211|Alphaproteobacteria T GGDEF domain - - - - - - - - - - - - EAL,GGDEF,PAS_3 CMS1_k127_937764_2 1297863.APJF01000003_gene1299 1.921e-58 213.0 COG2169@1|root,COG2169@2|Bacteria,1QTXR@1224|Proteobacteria,2UGSC@28211|Alphaproteobacteria,3K6UV@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K helix_turn_helix, arabinose operon control protein - - - - - - - - - - - - AraC_binding,Cupin_2,HTH_18 CMS1_k127_937764_1 1125973.JNLC01000018_gene2207 4.263e-114 382.0 COG2271@1|root,COG2271@2|Bacteria,1NJTU@1224|Proteobacteria,2TUBJ@28211|Alphaproteobacteria,3JU19@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G Major Facilitator Superfamily MA20_01130 - - - - - - - - - - - MFS_1 CMS1_k127_937764_3 1245469.S58_47360 1.588e-43 168.0 COG5483@1|root,COG5483@2|Bacteria,1N3XQ@1224|Proteobacteria,2UCV7@28211|Alphaproteobacteria,3JY6B@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function, DUF488 MA20_09495 - - - - - - - - - - - DUF488 CMS1_k127_937764_0 1411123.JQNH01000001_gene1727 8.609e-123 401.0 COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,2TS56@28211|Alphaproteobacteria 28211|Alphaproteobacteria J COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases - - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase CMS1_k127_942303_5 331869.BAL199_28220 6.598e-32 129.0 COG2717@1|root,COG2717@2|Bacteria,1RDUP@1224|Proteobacteria,2U5HG@28211|Alphaproteobacteria,4BQ7M@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria C Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain msrQ - - ko:K17247 - - - - ko00000 - - - Ferric_reduct CMS1_k127_942303_3 1304877.KI519400_gene847 6.484e-85 290.0 COG0596@1|root,COG0596@2|Bacteria,1R3U1@1224|Proteobacteria,2TVFV@28211|Alphaproteobacteria,3JQPU@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Alpha/beta hydrolase family MA20_01735 - - - - - - - - - - - Abhydrolase_6 CMS1_k127_942303_2 196490.AUEZ01000055_gene235 9.006e-89 295.0 2AUXR@1|root,2ZBPW@2|Bacteria,1RAID@1224|Proteobacteria,2U6KV@28211|Alphaproteobacteria,3JYM4@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_942303_4 460265.Mnod_3303 2.268e-74 254.0 COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,2U5GN@28211|Alphaproteobacteria,1JTP2@119045|Methylobacteriaceae 28211|Alphaproteobacteria H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN ubiX - 2.5.1.129 ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 M00117 R01238,R02952,R03367,R04985,R04986,R11225 RC00391,RC00814,RC03392 ko00000,ko00001,ko00002,ko01000 - - - Flavoprotein CMS1_k127_942303_1 1123060.JONP01000002_gene1007 1.872e-124 410.0 COG0654@1|root,COG0654@2|Bacteria,1MUN4@1224|Proteobacteria,2TQT8@28211|Alphaproteobacteria 28211|Alphaproteobacteria CH COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - - - - - - - - - - FAD_binding_3 CMS1_k127_942303_0 1123060.JONP01000001_gene1561 3.279e-141 464.0 COG0154@1|root,COG0154@2|Bacteria,1MWRI@1224|Proteobacteria,2TTJU@28211|Alphaproteobacteria,2JQU6@204441|Rhodospirillales 204441|Rhodospirillales J COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases - - - - - - - - - - - - Amidase CMS1_k127_949082_20 645991.Sgly_3222 2.29e-07 63.0 COG3409@1|root,COG3409@2|Bacteria,1TT2K@1239|Firmicutes,24965@186801|Clostridia,261US@186807|Peptococcaceae 186801|Clostridia M peptidoglycan-binding domain-containing protein - - - - - - - - - - - - LysM,NLPC_P60,PG_binding_1 CMS1_k127_949082_8 1279038.KB907344_gene3642 3.683e-59 229.0 COG0642@1|root,COG5002@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,2TRHH@28211|Alphaproteobacteria,2JQVJ@204441|Rhodospirillales 204441|Rhodospirillales T transduction histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,PAS_4,PAS_7,PAS_9 CMS1_k127_949082_21 113355.CM001775_gene3868 1.972e-05 57.0 COG2931@1|root,COG2931@2|Bacteria,1G1I0@1117|Cyanobacteria 1117|Cyanobacteria Q Hemolysin-type calcium-binding repeat (2 copies) - - - - - - - - - - - - He_PIG,HemolysinCabind,Peptidase_M10_C CMS1_k127_949082_16 269799.Gmet_1668 8.962e-31 131.0 2E3CB@1|root,32YBM@2|Bacteria,1N6WD@1224|Proteobacteria,42UIS@68525|delta/epsilon subdivisions,2WR4F@28221|Deltaproteobacteria,43VIR@69541|Desulfuromonadales 28221|Deltaproteobacteria S Domain of unknown function (DUF4154) - - - - - - - - - - - - DUF4154 CMS1_k127_949082_12 1207063.P24_10620 8.496e-49 179.0 COG1846@1|root,COG1846@2|Bacteria,1RA1V@1224|Proteobacteria,2U5W6@28211|Alphaproteobacteria,2JS3W@204441|Rhodospirillales 204441|Rhodospirillales K COG1846 Transcriptional regulators - - - - - - - - - - - - HTH_27 CMS1_k127_949082_17 670292.JH26_25670 2.585e-20 103.0 COG1199@1|root,COG3598@1|root,COG1199@2|Bacteria,COG3598@2|Bacteria,1MYGF@1224|Proteobacteria,2TTNY@28211|Alphaproteobacteria,1JXWK@119045|Methylobacteriaceae 28211|Alphaproteobacteria KL ATP-dependent helicase activity - - - ko:K06919 - - - - ko00000 - - - Prim-Pol,Toprim_3 CMS1_k127_949082_9 1123355.JHYO01000005_gene905 8.869e-51 189.0 COG2114@1|root,COG2114@2|Bacteria,1R110@1224|Proteobacteria,2TZP9@28211|Alphaproteobacteria,371KR@31993|Methylocystaceae 1224|Proteobacteria T Adenylyl- / guanylyl cyclase, catalytic domain - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - CHASE2,Guanylate_cyc CMS1_k127_949082_18 187303.BN69_2422 6.276e-20 92.0 COG0599@1|root,COG0599@2|Bacteria 2|Bacteria S peroxiredoxin activity - - 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 - R03470 RC00938 ko00000,ko00001,ko01000 - - - CMD CMS1_k127_949082_10 663610.JQKO01000002_gene1223 1.269e-50 188.0 COG1225@1|root,COG1225@2|Bacteria,1MWFZ@1224|Proteobacteria,2TRJM@28211|Alphaproteobacteria,3NCG2@45404|Beijerinckiaceae 28211|Alphaproteobacteria O Redoxin - - - - - - - - - - - - AhpC-TSA,Redoxin CMS1_k127_949082_4 1380391.JIAS01000011_gene4709 6.764e-131 432.0 COG0477@1|root,COG2814@2|Bacteria,1MWFH@1224|Proteobacteria,2TR0R@28211|Alphaproteobacteria,2JR1G@204441|Rhodospirillales 204441|Rhodospirillales EGP Major facilitator superfamily - - - - - - - - - - - - MFS_1 CMS1_k127_949082_0 1217718.ALOU01000075_gene4461 1.735e-183 594.0 COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2VHC1@28216|Betaproteobacteria,1K09M@119060|Burkholderiaceae 28216|Betaproteobacteria C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - 1.16.1.1 ko:K00520,ko:K21739 - - - - ko00000,ko01000 - - - Pyr_redox_2,Pyr_redox_dim CMS1_k127_949082_15 663610.JQKO01000002_gene1227 5.273e-44 166.0 COG3439@1|root,COG3439@2|Bacteria,1MZ38@1224|Proteobacteria,2U7V5@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Domain of unknown function DUF302 - - - - - - - - - - - - DUF302 CMS1_k127_949082_14 420324.KI912069_gene6356 3.611e-45 169.0 COG1672@1|root,COG1672@2|Bacteria,1N05N@1224|Proteobacteria,2UBUA@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Electron transfer DM13 - - - - - - - - - - - - DM13 CMS1_k127_949082_13 411684.HPDFL43_02200 2.32e-47 182.0 KOG3539@1|root,32TPV@2|Bacteria,1N2ES@1224|Proteobacteria 1224|Proteobacteria M Spondin_N - - - - - - - - - - - - Spond_N CMS1_k127_949082_19 1122929.KB908221_gene2817 2.599e-15 87.0 COG3219@1|root,COG3219@2|Bacteria,1QAP4@1224|Proteobacteria,2TTIN@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Putative DNA-binding domain - - - - - - - - - - - - DUF2063 CMS1_k127_949082_1 1122604.JONR01000009_gene2335 1.449e-155 503.0 COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,1RM9I@1236|Gammaproteobacteria,1X3HK@135614|Xanthomonadales 135614|Xanthomonadales C NADH dehydrogenase, FAD-containing subunit ndh - 1.6.99.3 ko:K03885 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - Pyr_redox_2 CMS1_k127_949082_6 663610.JQKO01000002_gene1223 4.346e-79 271.0 COG1225@1|root,COG1225@2|Bacteria,1MWFZ@1224|Proteobacteria,2TRJM@28211|Alphaproteobacteria,3NCG2@45404|Beijerinckiaceae 28211|Alphaproteobacteria O Redoxin - - - - - - - - - - - - AhpC-TSA,Redoxin CMS1_k127_949082_7 1040986.ATYO01000034_gene109 1.238e-73 261.0 COG0583@1|root,COG0583@2|Bacteria,1R51E@1224|Proteobacteria,2TZIK@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Transcriptional regulator - - - - - - - - - - - - HTH_1,LysR_substrate CMS1_k127_949082_5 1041159.AZUW01000015_gene363 8.609e-111 365.0 COG1028@1|root,COG1028@2|Bacteria,1MU5Y@1224|Proteobacteria,2TRNQ@28211|Alphaproteobacteria,4BDKG@82115|Rhizobiaceae 28211|Alphaproteobacteria IQ KR domain - - 1.1.1.30 ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 M00088 R01361 RC00117 ko00000,ko00001,ko00002,ko01000 - - - adh_short,adh_short_C2 CMS1_k127_949082_2 395963.Bind_1734 2.398e-144 466.0 COG1752@1|root,COG1752@2|Bacteria,1MVHW@1224|Proteobacteria,2TS4V@28211|Alphaproteobacteria 28211|Alphaproteobacteria S esterase of the alpha-beta hydrolase superfamily - - - ko:K07001 - - - - ko00000 - - - Patatin CMS1_k127_949082_3 1207063.P24_03156 6.343e-133 437.0 COG2114@1|root,COG2114@2|Bacteria,1MV1V@1224|Proteobacteria,2TRUC@28211|Alphaproteobacteria,2JQP6@204441|Rhodospirillales 204441|Rhodospirillales T COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_cyc CMS1_k127_949082_11 224911.27351029 4.936e-49 179.0 COG1917@1|root,COG1917@2|Bacteria,1PBNJ@1224|Proteobacteria,2U1VG@28211|Alphaproteobacteria,3JW2I@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Cupin domain - - - - - - - - - - - - Cupin_2 CMS1_k127_951131_3 1040989.AWZU01000014_gene4608 2.154e-102 355.0 COG1120@1|root,COG1120@2|Bacteria,1MUNG@1224|Proteobacteria,2TV55@28211|Alphaproteobacteria,3JY8H@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P ATPases associated with a variety of cellular activities - - 3.6.3.34 ko:K02013 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran CMS1_k127_951131_1 1040989.AWZU01000014_gene4609 1.63e-158 506.0 COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,2TR9A@28211|Alphaproteobacteria,3JS3U@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily - - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - FecCD CMS1_k127_951131_0 1380355.JNIJ01000010_gene1457 2.51e-167 533.0 COG0614@1|root,COG0614@2|Bacteria,1NVK4@1224|Proteobacteria,2TRJ0@28211|Alphaproteobacteria,3JVNC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P Periplasmic binding protein - - - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - Peripla_BP_2 CMS1_k127_951131_2 1038859.AXAU01000005_gene5212 4.106e-128 415.0 COG2998@1|root,COG2998@2|Bacteria,1MVSF@1224|Proteobacteria,2TU33@28211|Alphaproteobacteria,3JUMN@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H PBP superfamily domain tupA - - ko:K05772 ko02010,map02010 M00186 - - ko00000,ko00001,ko00002,ko02000 3.A.1.6.2,3.A.1.6.4 - - PBP_like_2 CMS1_k127_951131_4 1380394.JADL01000001_gene2557 1.497e-95 318.0 COG1126@1|root,COG1126@2|Bacteria,1MWKQ@1224|Proteobacteria,2TSCU@28211|Alphaproteobacteria,2JRVW@204441|Rhodospirillales 204441|Rhodospirillales E ABC transporter - - - - - - - - - - - - ABC_tran CMS1_k127_951131_5 1038859.AXAU01000005_gene5210 4.482e-24 101.0 COG4662@1|root,COG4662@2|Bacteria,1MZVS@1224|Proteobacteria,2TUHN@28211|Alphaproteobacteria,3JUNT@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H ABC-type tungstate transport system, periplasmic component MA20_34300 - - ko:K05773 ko02010,map02010 M00186 - - ko00000,ko00001,ko00002,ko02000 3.A.1.6.2,3.A.1.6.4 - - BPD_transp_1 CMS1_k127_9565_2 1429916.X566_09920 1.454e-73 249.0 COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,2TSRD@28211|Alphaproteobacteria,3JTS8@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate asd - 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC CMS1_k127_9565_3 1297863.APJF01000016_gene4307 8.703e-37 150.0 2BIMX@1|root,32CUX@2|Bacteria,1QKNA@1224|Proteobacteria,2U0TA@28211|Alphaproteobacteria,3JX4T@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_9565_4 1040989.AWZU01000033_gene3607 0.0002609 48.0 2A8WA@1|root,30XZN@2|Bacteria,1RHG7@1224|Proteobacteria,2U9J4@28211|Alphaproteobacteria,3JYW8@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_9565_0 1380355.JNIJ01000038_gene4851 3.161e-192 606.0 COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,2TQKG@28211|Alphaproteobacteria,3JRCP@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate leuB GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh CMS1_k127_9565_1 69279.BG36_15990 1.919e-186 593.0 COG1752@1|root,COG1752@2|Bacteria,1MWH2@1224|Proteobacteria,2TU16@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Protein of unknown function (DUF3376) - - - - - - - - - - - - DUF3376,Patatin CMS1_k127_960640_0 1279038.KB907339_gene1325 0.0 1202.0 COG0654@1|root,COG1902@1|root,COG0654@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,2TQPY@28211|Alphaproteobacteria,2JQUF@204441|Rhodospirillales 204441|Rhodospirillales C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family namA - - - - - - - - - - - Oxidored_FMN CMS1_k127_960640_2 1380350.JIAP01000008_gene2185 1.281e-73 262.0 COG1028@1|root,COG1028@2|Bacteria,1MUS7@1224|Proteobacteria,2TTYG@28211|Alphaproteobacteria,43I0Q@69277|Phyllobacteriaceae 28211|Alphaproteobacteria IQ Belongs to the short-chain dehydrogenases reductases (SDR) family bdh - - - - - - - - - - - adh_short,adh_short_C2 CMS1_k127_960640_3 89187.ISM_04110 2.924e-42 162.0 COG1846@1|root,COG1846@2|Bacteria,1MZE9@1224|Proteobacteria,2TSUB@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Transcriptional regulator, MarR family - - - - - - - - - - - - MarR,MarR_2 CMS1_k127_960640_1 1123366.TH3_12165 4.615e-130 429.0 COG1024@1|root,COG1024@2|Bacteria,1MXHV@1224|Proteobacteria,2TTEG@28211|Alphaproteobacteria,2JQRS@204441|Rhodospirillales 204441|Rhodospirillales I COG1024 Enoyl-CoA hydratase carnithine racemase - - - - - - - - - - - - ECH_1 CMS1_k127_963727_2 1187851.A33M_0839 5.388e-183 589.0 COG0025@1|root,COG0025@2|Bacteria,1MW5T@1224|Proteobacteria,2TSHB@28211|Alphaproteobacteria,3FEEW@34008|Rhodovulum 28211|Alphaproteobacteria P Sodium/hydrogen exchanger family MA20_23215 - - ko:K03316 - - - - ko00000 2.A.36 - - Na_H_Exchanger CMS1_k127_963727_7 113395.AXAI01000007_gene1287 5.403e-109 364.0 COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,2TR79@28211|Alphaproteobacteria,3JTEJ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H Belongs to the FPP GGPP synthase family ispA GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009536,GO:0009842,GO:0009987,GO:0016114,GO:0016740,GO:0016765,GO:0019637,GO:0033385,GO:0033386,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0090407,GO:1901576 2.5.1.1,2.5.1.10 ko:K00795 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364 R01658,R02003 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - - polyprenyl_synt CMS1_k127_963727_12 504832.OCAR_4115 3.126e-78 268.0 COG0744@1|root,COG0744@2|Bacteria,1RDAQ@1224|Proteobacteria,2U0NP@28211|Alphaproteobacteria,3JR05@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors mtgA - 2.4.1.129 ko:K03814 ko00550,map00550 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly CMS1_k127_963727_18 1125973.JNLC01000013_gene4089 1.915e-29 118.0 COG0333@1|root,COG0333@2|Bacteria,1PU3Y@1224|Proteobacteria,2UF54@28211|Alphaproteobacteria,3K11R@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Belongs to the bacterial ribosomal protein bL32 family rpmF - - ko:K02911 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_L32p CMS1_k127_963727_15 1187851.A33M_0835 7.695e-43 160.0 2E6XE@1|root,331GU@2|Bacteria,1N7WP@1224|Proteobacteria,2UG23@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_963727_3 1287116.X734_12695 7.967e-174 561.0 COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,2TQWP@28211|Alphaproteobacteria,43I3U@69277|Phyllobacteriaceae 28211|Alphaproteobacteria E Gamma-glutamyltranspeptidase ggt1 - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept CMS1_k127_963727_9 1304275.C41B8_03371 3.251e-102 344.0 COG0620@1|root,COG0620@2|Bacteria,1MV2Z@1224|Proteobacteria,1RPTM@1236|Gammaproteobacteria 1236|Gammaproteobacteria E methionine synthase yxjG - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_2 CMS1_k127_963727_17 1027273.GZ77_07460 5.37e-32 134.0 COG1309@1|root,COG1309@2|Bacteria 2|Bacteria K transcriptional regulator - - - - - - - - - - - - TetR_C_4,TetR_N CMS1_k127_963727_5 1038866.KB902770_gene4445 4.946e-131 440.0 COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,2TTX0@28211|Alphaproteobacteria,3JWV6@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I AMP-binding enzyme - - - - - - - - - - - - AMP-binding CMS1_k127_963727_4 883078.HMPREF9695_00461 1.444e-135 447.0 COG0683@1|root,COG0683@2|Bacteria 2|Bacteria E ABC-type branched-chain amino acid transport systems, periplasmic component - - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 CMS1_k127_963727_8 883078.HMPREF9695_00457 3.631e-107 356.0 COG0559@1|root,COG0559@2|Bacteria,1N54M@1224|Proteobacteria,2TTF5@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Belongs to the binding-protein-dependent transport system permease family - - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 CMS1_k127_963727_6 883078.HMPREF9695_00458 2.029e-121 400.0 COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,2TT26@28211|Alphaproteobacteria,3JSMK@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Belongs to the binding-protein-dependent transport system permease family - - - ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 CMS1_k127_963727_13 883078.HMPREF9695_00459 2.157e-75 276.0 COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2TT8N@28211|Alphaproteobacteria 28211|Alphaproteobacteria E branched-chain amino acid - - - - - - - - - - - - ABC_tran CMS1_k127_963727_11 883078.HMPREF9695_00460 4.653e-83 285.0 COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,2TYIJ@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Branched-chain amino acid ATP-binding cassette transporter - - - - - - - - - - - - ABC_tran,BCA_ABC_TP_C CMS1_k127_963727_10 1120956.JHZK01000016_gene2161 2.582e-84 295.0 COG3919@1|root,COG3919@2|Bacteria,1R94Z@1224|Proteobacteria,2UKDM@28211|Alphaproteobacteria 28211|Alphaproteobacteria S ATP-grasp - - - - - - - - - - - - CPSase_L_D2 CMS1_k127_963727_14 935840.JAEQ01000011_gene1863 3.78e-63 239.0 COG2348@1|root,COG2348@2|Bacteria,1Q48P@1224|Proteobacteria,2VAR6@28211|Alphaproteobacteria,43QNM@69277|Phyllobacteriaceae 28211|Alphaproteobacteria V Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_6 CMS1_k127_963727_16 1120956.JHZK01000016_gene2163 3.039e-38 160.0 COG2244@1|root,COG2244@2|Bacteria,1N49M@1224|Proteobacteria,2UEFC@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Polysaccharide biosynthesis C-terminal domain - - - - - - - - - - - - Polysacc_synt,Polysacc_synt_C CMS1_k127_963727_19 1385935.N836_22050 4.574e-23 108.0 2DDZV@1|root,32U2A@2|Bacteria,1G7V6@1117|Cyanobacteria,1HCAN@1150|Oscillatoriales 1117|Cyanobacteria - - - - - - - - - - - - - - - CMS1_k127_963727_0 426117.M446_5647 7.842e-302 932.0 COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,2TVYU@28211|Alphaproteobacteria,1JXDZ@119045|Methylobacteriaceae 28211|Alphaproteobacteria EQ Hydantoinase B/oxoprolinase - - 3.5.2.14 ko:K01474 ko00330,ko01100,map00330,map01100 - R03187 RC00632 ko00000,ko00001,ko01000 - - - Hydantoinase_B CMS1_k127_963727_1 426117.M446_5648 2.107e-291 909.0 COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,2TQZ6@28211|Alphaproteobacteria,1JUGP@119045|Methylobacteriaceae 28211|Alphaproteobacteria EQ PFAM Hydantoinase oxoprolinase - - 3.5.2.14 ko:K01473 ko00330,ko01100,map00330,map01100 - R03187 RC00632 ko00000,ko00001,ko01000 - - - Hydant_A_N,Hydantoinase_A CMS1_k127_963921_4 1125973.JNLC01000010_gene1317 1.411e-09 58.0 COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2TQP0@28211|Alphaproteobacteria,3JRI2@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P Belongs to the ABC transporter superfamily yejF GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008144,GO:0008150,GO:0015399,GO:0015405,GO:0015833,GO:0015893,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035672,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042884,GO:0042886,GO:0042891,GO:0043167,GO:0043168,GO:0043492,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K02031,ko:K02032,ko:K13896 ko02010,ko02024,map02010,map02024 M00239,M00349 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.21,3.A.1.5.24 - - ABC_tran,oligo_HPY CMS1_k127_963921_3 316058.RPB_1775 1.062e-57 208.0 COG0494@1|root,COG0494@2|Bacteria,1RDMW@1224|Proteobacteria,2TTKQ@28211|Alphaproteobacteria,3K6KH@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L NUDIX domain nudK - 3.6.1.13 ko:K01515 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000 - - - NUDIX CMS1_k127_963921_2 1187851.A33M_3450 1.039e-74 261.0 COG1651@1|root,COG1651@2|Bacteria,1RIBE@1224|Proteobacteria,2U9VB@28211|Alphaproteobacteria 28211|Alphaproteobacteria O PFAM DSBA oxidoreductase - - - - - - - - - - - - DSBA,Thioredoxin_4 CMS1_k127_963921_1 936455.KI421499_gene5693 7.035e-111 364.0 COG0791@1|root,COG0791@2|Bacteria,1MW03@1224|Proteobacteria,2TSFG@28211|Alphaproteobacteria,3JQZJ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria M NlpC/P60 family - - - - - - - - - - - - NLPC_P60,SH3_3 CMS1_k127_963921_0 1187851.A33M_3698 3.163e-117 381.0 COG0260@1|root,COG0260@2|Bacteria,1MUIN@1224|Proteobacteria,2TSI6@28211|Alphaproteobacteria,3FCUG@34008|Rhodovulum 28211|Alphaproteobacteria E Cytosol aminopeptidase family, catalytic domain pepA - 3.4.11.1 ko:K01255 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - Peptidase_M17 CMS1_k127_976065_2 113395.AXAI01000004_gene4585 3.758e-195 609.0 COG2368@1|root,COG2368@2|Bacteria,1PEQG@1224|Proteobacteria,2TVQ7@28211|Alphaproteobacteria,3JWEV@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria Q 4-hydroxyphenylacetate 3-hydroxylase C terminal - - - - - - - - - - - - HpaB,HpaB_N CMS1_k127_976065_7 1120956.JHZK01000005_gene2364 2.677e-40 156.0 COG1853@1|root,COG1853@2|Bacteria,1RGYM@1224|Proteobacteria,2UCHI@28211|Alphaproteobacteria,1JP71@119043|Rhodobiaceae 28211|Alphaproteobacteria S Flavin reductase like domain ntaB - - - - - - - - - - - Abhydrolase_1,Flavin_Reduct CMS1_k127_976065_9 1205680.CAKO01000029_gene5224 5.433e-28 117.0 COG0607@1|root,COG0607@2|Bacteria,1RDIR@1224|Proteobacteria,2U820@28211|Alphaproteobacteria 28211|Alphaproteobacteria P Protein of unknown function (DUF2892) - - - - - - - - - - - - DUF2892,Rhodanese CMS1_k127_976065_8 1411123.JQNH01000001_gene2851 1.096e-28 118.0 COG0640@1|root,COG0640@2|Bacteria,1N72Q@1224|Proteobacteria,2UFSY@28211|Alphaproteobacteria 28211|Alphaproteobacteria K Transcriptional nolR GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - ko:K22042 - - - - ko00000,ko03000 - - - HTH_5 CMS1_k127_976065_0 1040989.AWZU01000019_gene1891 1.077e-265 834.0 COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,2TR7S@28211|Alphaproteobacteria,3JRU1@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus phbC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K03821 ko00650,map00650 - R04254 RC00004 ko00000,ko00001,ko01000 - - - Abhydrolase_1,PhaC_N CMS1_k127_976065_1 1187851.A33M_4249 8.511e-227 710.0 COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,2TRE3@28211|Alphaproteobacteria 28211|Alphaproteobacteria E Aminotransferase aatC GO:0003674,GO:0003824,GO:0004021,GO:0006082,GO:0006090,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009078,GO:0009079,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019272,GO:0019752,GO:0030632,GO:0032787,GO:0042851,GO:0042852,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0047635,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - ko:K14261 - - - - ko00000,ko01000,ko01007 - - - Aminotran_1_2 CMS1_k127_976065_3 1038867.AXAY01000006_gene4034 3.482e-188 597.0 COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,2TQWS@28211|Alphaproteobacteria,3JTE6@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E homoserine dehydrogenase hom GO:0003674,GO:0003824,GO:0004412,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.3 ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00017,M00018 R01773,R01775 RC00087 ko00000,ko00001,ko00002,ko01000 - - - ACT,Homoserine_dh,NAD_binding_3 CMS1_k127_976065_4 1429916.X566_19815 3.327e-162 515.0 COG1494@1|root,COG1494@2|Bacteria,1MUB1@1224|Proteobacteria,2TSPE@28211|Alphaproteobacteria,3JSWJ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria G Bacterial fructose-1,6-bisphosphatase, glpX-encoded glpX - 3.1.3.11,3.1.3.37 ko:K02446,ko:K11532 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00165,M00167 R00762,R01845,R04780 RC00017 ko00000,ko00001,ko00002,ko01000 - - - FBPase_glpX CMS1_k127_976065_5 479434.Sthe_1846 1.286e-90 309.0 28J6C@1|root,2Z923@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - CMS1_k127_976065_6 504832.OCAR_6019 2.7e-88 295.0 COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,2TRZQ@28211|Alphaproteobacteria,3JRYX@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L DHH family recJ GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008297,GO:0008409,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0035312,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0045145,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 CMS1_k127_977135_29 1187851.A33M_1814 2.351e-17 94.0 COG4223@1|root,COG4223@2|Bacteria,1Q3YS@1224|Proteobacteria,2VAHN@28211|Alphaproteobacteria,3FEI1@34008|Rhodovulum 28211|Alphaproteobacteria DZ transferase activity, transferring acyl groups other than amino-acyl groups - - - - - - - - - - - - - CMS1_k127_977135_22 1187851.A33M_1813 1.932e-51 190.0 COG1587@1|root,COG1587@2|Bacteria,1NMTP@1224|Proteobacteria,2U1Y2@28211|Alphaproteobacteria 28211|Alphaproteobacteria H synthase hemD - 4.2.1.75 ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R03165 RC01861 ko00000,ko00001,ko00002,ko01000 - - - HEM4 CMS1_k127_977135_13 266779.Meso_3202 5.037e-106 356.0 COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,2TS3D@28211|Alphaproteobacteria,43HQC@69277|Phyllobacteriaceae 28211|Alphaproteobacteria H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps hemC - 2.5.1.61 ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R00084 RC02317 ko00000,ko00001,ko00002,ko01000 - - - Porphobil_deam,Porphobil_deamC CMS1_k127_977135_8 1187851.A33M_1811 4.31e-158 506.0 COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,2TSF7@28211|Alphaproteobacteria,3FCTS@34008|Rhodovulum 28211|Alphaproteobacteria O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction tsaD GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360,GO:1901564 2.3.1.234 ko:K01409 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 CMS1_k127_977135_9 316058.RPB_0316 5.24e-141 456.0 COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,2TT75@28211|Alphaproteobacteria,3JT75@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria I Glycerol-3-phosphate dehydrogenase gpsA GO:0003674,GO:0003824,GO:0006072,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 - R00842,R00844 RC00029 ko00000,ko00001,ko01000 - - - NAD_Gly3P_dh_C,NAD_Gly3P_dh_N CMS1_k127_977135_19 1411123.JQNH01000001_gene22 3.383e-58 204.0 COG2947@1|root,COG2947@2|Bacteria,1RHRU@1224|Proteobacteria,2U71N@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Ubiquinol-cytochrome C reductase MA20_25125 - - - - - - - - - - - EVE CMS1_k127_977135_27 266779.Meso_3385 2.052e-36 143.0 2DPP7@1|root,332UY@2|Bacteria,1N75H@1224|Proteobacteria,2UFXZ@28211|Alphaproteobacteria,43KVV@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF1761) - - - - - - - - - - - - DUF1761 CMS1_k127_977135_1 1187851.A33M_0272 0.0 1165.0 COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2TRKS@28211|Alphaproteobacteria,3FCVM@34008|Rhodovulum 28211|Alphaproteobacteria I Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA acsA - 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C CMS1_k127_977135_18 1197906.CAJQ02000029_gene4054 2.769e-60 212.0 COG1376@1|root,COG1376@2|Bacteria,1MVYT@1224|Proteobacteria,2U7F8@28211|Alphaproteobacteria,3JTDU@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S L,D-transpeptidase catalytic domain MA20_25100 - - - - - - - - - - - YkuD CMS1_k127_977135_24 1411123.JQNH01000001_gene2631 3.313e-49 181.0 COG1376@1|root,COG1376@2|Bacteria,1MVYT@1224|Proteobacteria,2U7F8@28211|Alphaproteobacteria 28211|Alphaproteobacteria S PFAM ErfK YbiS YcfS YnhG family protein MA20_25100 - - - - - - - - - - - YkuD CMS1_k127_977135_6 224911.27348828 6.919e-189 599.0 COG0144@1|root,COG0144@2|Bacteria,1MWPE@1224|Proteobacteria,2TSIA@28211|Alphaproteobacteria,3JTZG@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria J Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family rsmB - 2.1.1.176 ko:K03500 - - - - ko00000,ko01000,ko03009 - - - Methyltr_RsmB-F,NusB CMS1_k127_977135_3 1187851.A33M_3466 2.912e-216 687.0 COG5360@1|root,COG5360@2|Bacteria,1MUJ4@1224|Proteobacteria,2TR5G@28211|Alphaproteobacteria,3FD9I@34008|Rhodovulum 28211|Alphaproteobacteria S Heparinase II/III-like protein MA20_25080 - - - - - - - - - - - Hepar_II_III CMS1_k127_977135_2 666684.AfiDRAFT_1483 5.595e-272 843.0 COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,2TRMY@28211|Alphaproteobacteria,3JTQW@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria F Bifunctional purine biosynthesis protein PurH purH - 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 - - - AICARFT_IMPCHas,MGS CMS1_k127_977135_0 670292.JH26_02580 0.0 1799.0 COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,2TS89@28211|Alphaproteobacteria,1JT0S@119045|Methylobacteriaceae 28211|Alphaproteobacteria E PFAM NAD-glutamate dehydrogenase gdhB GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0008150,GO:0008152,GO:0016491,GO:0016638,GO:0016639,GO:0055114 1.4.1.2 ko:K15371 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 - R00243 RC00006,RC02799 ko00000,ko00001,ko01000 - - - Bac_GDH CMS1_k127_977135_14 78245.Xaut_1433 1.606e-87 295.0 COG2128@1|root,COG2128@2|Bacteria,1MUDM@1224|Proteobacteria,2TTY5@28211|Alphaproteobacteria,3F16W@335928|Xanthobacteraceae 28211|Alphaproteobacteria O Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - - - - - - - - - - CMD CMS1_k127_977135_4 1304878.AUGD01000003_gene2507 1.643e-212 676.0 COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,2TR49@28211|Alphaproteobacteria,3JRHC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E Gamma-glutamyltranspeptidase ggt - 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept CMS1_k127_977135_23 1121861.KB899918_gene3277 1.977e-49 194.0 COG2606@1|root,COG2606@2|Bacteria,1RD82@1224|Proteobacteria,2U7H0@28211|Alphaproteobacteria,2JSQY@204441|Rhodospirillales 204441|Rhodospirillales S Aminoacyl-tRNA editing domain - - - - - - - - - - - - tRNA_edit CMS1_k127_977135_16 1038859.AXAU01000001_gene3775 6.926e-64 223.0 COG1495@1|root,COG1495@2|Bacteria,1RKPG@1224|Proteobacteria,2U89W@28211|Alphaproteobacteria,3JUIX@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O Disulfide bond formation protein DsbB - - - - - - - - - - - - DsbB CMS1_k127_977135_30 398525.KB900701_gene4465 3.179e-06 53.0 2DHZU@1|root,301ID@2|Bacteria,1N863@1224|Proteobacteria,2UHUG@28211|Alphaproteobacteria,3K1FX@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_977135_17 1187851.A33M_0009 1.259e-61 227.0 COG3760@1|root,COG3760@2|Bacteria,1RDIG@1224|Proteobacteria,2U87T@28211|Alphaproteobacteria 28211|Alphaproteobacteria S YbaK prolyl-tRNA synthetase - - - ko:K19055 - - - - ko00000,ko01000,ko03016 - - - tRNA_edit CMS1_k127_977135_11 1040989.AWZU01000070_gene3322 2.878e-131 426.0 COG3118@1|root,COG3118@2|Bacteria,1MV0R@1224|Proteobacteria,2TS5X@28211|Alphaproteobacteria,3JRJ9@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria O Tetratricopeptide repeat trxA2 - - ko:K03671,ko:K05838 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - TPR_19,TPR_20,Thioredoxin CMS1_k127_977135_12 1380355.JNIJ01000027_gene801 4.556e-113 368.0 COG2802@1|root,COG2802@2|Bacteria,1NV9N@1224|Proteobacteria,2TQZ4@28211|Alphaproteobacteria,3JRXV@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S ATP-dependent protease La (LON) substrate-binding domain lonD - 3.4.21.53 ko:K01338,ko:K07157 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - LON_substr_bdg CMS1_k127_977135_28 1040989.AWZU01000070_gene3329 1.66e-25 108.0 COG2835@1|root,COG2835@2|Bacteria,1N6Y2@1224|Proteobacteria,2UF4N@28211|Alphaproteobacteria,3K13U@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Belongs to the UPF0434 family MA20_24965 - - ko:K09791 - - - - ko00000 - - - Trm112p CMS1_k127_977135_15 1187851.A33M_0013 2.845e-82 278.0 COG0625@1|root,COG0625@2|Bacteria,1RA4Y@1224|Proteobacteria,2U5B6@28211|Alphaproteobacteria,3FEM1@34008|Rhodovulum 28211|Alphaproteobacteria O Glutathione S-transferase, N-terminal domain - - - - - - - - - - - - GST_C,GST_C_3,GST_N_3 CMS1_k127_977135_7 1304878.AUGD01000003_gene2520 4.363e-177 563.0 COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,2TRZU@28211|Alphaproteobacteria,3JU6C@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria CH TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family ubiH GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016491,GO:0019168,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901576,GO:1901661,GO:1901663 - ko:K03185 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R04989,R08773 RC02670 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_3 CMS1_k127_977135_10 1211115.ALIQ01000171_gene4116 6.609e-133 435.0 COG1946@1|root,COG1946@2|Bacteria,1MV9R@1224|Proteobacteria,2TRFD@28211|Alphaproteobacteria,3NAH7@45404|Beijerinckiaceae 28211|Alphaproteobacteria I Thioesterase-like superfamily tesB GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016042,GO:0016054,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042802,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072329,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901575 - ko:K10805 ko01040,map01040 - - - ko00000,ko00001,ko01000,ko01004 - - - 4HBT_3 CMS1_k127_977135_26 316058.RPB_3932 2.929e-39 158.0 2BWZZ@1|root,2Z86E@2|Bacteria,1MW89@1224|Proteobacteria,2U08W@28211|Alphaproteobacteria,3JVIA@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S Protein of unknown function (DUF2927) - - - - - - - - - - - - DUF2927 CMS1_k127_977135_21 666684.AfiDRAFT_1498 1.156e-51 184.0 COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2U952@28211|Alphaproteobacteria,3JYV3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K Belongs to the P(II) protein family glnK - - ko:K04751,ko:K04752 ko02020,map02020 - - - ko00000,ko00001 - - - P-II CMS1_k127_977135_5 1126627.BAWE01000002_gene1186 8.933e-195 616.0 COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,2TT2J@28211|Alphaproteobacteria,3JQXC@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P Ammonium Transporter MA20_24940 - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp CMS1_k127_977135_20 224911.27348861 2.945e-57 201.0 COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2U952@28211|Alphaproteobacteria,3JYV3@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K Belongs to the P(II) protein family glnK - - ko:K04751,ko:K04752 ko02020,map02020 - - - ko00000,ko00001 - - - P-II CMS1_k127_977135_25 1430440.MGMSRv2_0365 1.224e-46 175.0 COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,2TT2J@28211|Alphaproteobacteria,2JPX1@204441|Rhodospirillales 204441|Rhodospirillales U Ammonium transporter amtB - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp CMS1_k127_991554_0 381666.H16_A1706 8.64e-133 452.0 COG1404@1|root,COG1404@2|Bacteria,1REVZ@1224|Proteobacteria,2WDV2@28216|Betaproteobacteria,1KB1U@119060|Burkholderiaceae 28216|Betaproteobacteria O Subtilase family - - - ko:K17734 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S8 CMS1_k127_991554_1 1210884.HG799465_gene11348 3.156e-09 57.0 COG2217@1|root,COG2217@2|Bacteria,2IXAD@203682|Planctomycetes 203682|Planctomycetes P heavy metal translocating P-type ATPase - - 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,HMA,Hydrolase,YHS CMS1_k127_998304_0 331869.BAL199_27601 0.0 1390.0 COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,1MW3N@1224|Proteobacteria,2TTPX@28211|Alphaproteobacteria,4BT8J@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria C Molydopterin dinucleotide binding domain fdhF - 1.17.1.9 ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding CMS1_k127_998304_18 1238182.C882_0327 1.067e-22 106.0 2DP0X@1|root,3302S@2|Bacteria,1RIRD@1224|Proteobacteria,2UA7P@28211|Alphaproteobacteria,2JU7H@204441|Rhodospirillales 204441|Rhodospirillales S Protein of unknown function (DUF3306) - - - - - - - - - - - - DUF3306 CMS1_k127_998304_16 1089552.KI911559_gene1668 7.877e-36 145.0 COG0746@1|root,COG0746@2|Bacteria,1RB53@1224|Proteobacteria,2TUXF@28211|Alphaproteobacteria,2JTM9@204441|Rhodospirillales 204441|Rhodospirillales H Protein of unknown function (DUF3305) - - - - - - - - - - - - DUF3305 CMS1_k127_998304_19 883080.HMPREF9697_03785 7.375e-10 65.0 2EH97@1|root,33B11@2|Bacteria,1MZP0@1224|Proteobacteria,2UBWB@28211|Alphaproteobacteria,3K01N@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria S TIGRFAM formate dehydrogenase region TAT target - - - - - - - - - - - - - CMS1_k127_998304_9 1380394.JADL01000001_gene2455 3.105e-98 327.0 COG3381@1|root,COG4197@1|root,COG3381@2|Bacteria,COG4197@2|Bacteria,1MWWM@1224|Proteobacteria,2TU06@28211|Alphaproteobacteria,2JS77@204441|Rhodospirillales 204441|Rhodospirillales S Nitrate reductase delta subunit - - - - - - - - - - - - Nitrate_red_del,YdaS_antitoxin CMS1_k127_998304_5 1380394.JADL01000001_gene2453 4.091e-142 458.0 2C7F6@1|root,2Z8AK@2|Bacteria,1PEE5@1224|Proteobacteria,2TTH2@28211|Alphaproteobacteria,2JR3R@204441|Rhodospirillales 204441|Rhodospirillales - - - - - - - - - - - - - - - CMS1_k127_998304_14 318996.AXAZ01000004_gene6270 2.165e-57 211.0 28NIR@1|root,2ZBK2@2|Bacteria,1RAAF@1224|Proteobacteria,2U5XR@28211|Alphaproteobacteria,3JT0S@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - CMS1_k127_998304_10 319003.Bra1253DRAFT_01662 3.869e-84 286.0 COG0340@1|root,COG0340@2|Bacteria,1N1WU@1224|Proteobacteria,2TQK4@28211|Alphaproteobacteria,3JTCW@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria H Biotin/lipoate A/B protein ligase family - - - - - - - - - - - - BPL_LplA_LipB_2,DUF4444 CMS1_k127_998304_1 1380394.JADL01000001_gene2450 1.325e-302 940.0 COG1145@1|root,COG1145@2|Bacteria,1MWHY@1224|Proteobacteria,2TS71@28211|Alphaproteobacteria,2JR2H@204441|Rhodospirillales 204441|Rhodospirillales C 4Fe-4S binding domain - - - - - - - - - - - - Fer4,Fer4_7 CMS1_k127_998304_11 1089551.KE386572_gene1707 1.016e-64 231.0 COG0500@1|root,COG2226@2|Bacteria,1PPKI@1224|Proteobacteria,2TRIB@28211|Alphaproteobacteria,4BSGF@82117|unclassified Alphaproteobacteria 28211|Alphaproteobacteria Q ubiE/COQ5 methyltransferase family - - - - - - - - - - - - Methyltransf_11,Methyltransf_25,Ubie_methyltran CMS1_k127_998304_4 709797.CSIRO_1916 9.573e-184 583.0 COG2319@1|root,COG3474@1|root,COG2319@2|Bacteria,COG3474@2|Bacteria,1MWJA@1224|Proteobacteria,2TRIX@28211|Alphaproteobacteria,3JS61@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C WD domain, G-beta repeat - - - ko:K08738 ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416 M00595 R10151 RC03151,RC03152 ko00000,ko00001,ko00002 3.D.4.6 - - Cytochrom_C,WD40 CMS1_k127_998304_3 1123072.AUDH01000033_gene1974 1.158e-249 788.0 COG0303@1|root,COG1910@1|root,COG0303@2|Bacteria,COG1910@2|Bacteria,1MVD5@1224|Proteobacteria,2TVN2@28211|Alphaproteobacteria,2JVBX@204441|Rhodospirillales 204441|Rhodospirillales HP MoeA C-terminal region (domain IV) - - - - - - - - - - - - MoCF_biosynth,MoeA_C,MoeA_N,PBP_like CMS1_k127_998304_12 441620.Mpop_2963 1.011e-63 233.0 COG0303@1|root,COG0303@2|Bacteria,1PDCE@1224|Proteobacteria,2TR67@28211|Alphaproteobacteria,1JTGX@119045|Methylobacteriaceae 28211|Alphaproteobacteria H MoeA domain protein domain I and II - - - - - - - - - - - - MoCF_biosynth,MoeA_C,MoeA_N CMS1_k127_998304_7 1254432.SCE1572_16030 9.694e-121 400.0 COG0620@1|root,COG0620@2|Bacteria,1MV2Z@1224|Proteobacteria,42NPA@68525|delta/epsilon subdivisions,2WT46@28221|Deltaproteobacteria 28221|Deltaproteobacteria E Cobalamin-independent synthase, Catalytic domain - - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_2 CMS1_k127_998304_17 1411123.JQNH01000001_gene40 4.018e-23 102.0 COG0425@1|root,COG0425@2|Bacteria 2|Bacteria O sulfur carrier activity MA20_10255 - - ko:K04085 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - TusA CMS1_k127_998304_2 1197906.CAJQ02000004_gene3003 1.847e-282 882.0 COG0457@1|root,COG3629@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,3JR8W@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Adenylate cyclase - - - - - - - - - - - - BTAD,Trans_reg_C CMS1_k127_998304_6 1038859.AXAU01000019_gene4841 1.89e-121 395.0 COG0500@1|root,COG2226@2|Bacteria,1MXP4@1224|Proteobacteria,2TQU4@28211|Alphaproteobacteria,3JVXR@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria Q ubiE/COQ5 methyltransferase family - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 CMS1_k127_998304_13 99598.Cal7507_1045 2.854e-63 239.0 28JPA@1|root,2Z9FC@2|Bacteria,1G2DB@1117|Cyanobacteria,1HQP9@1161|Nostocales 1117|Cyanobacteria - - - - - - - - - - - - - - - CMS1_k127_998304_15 331869.BAL199_29505 2.283e-43 161.0 COG0251@1|root,COG0251@2|Bacteria,1RH61@1224|Proteobacteria,2UAE3@28211|Alphaproteobacteria 28211|Alphaproteobacteria J Translation initiation inhibitor, yjgF family rutC - - - - - - - - - - - Ribonuc_L-PSP CMS1_k127_998304_8 1472418.BBJC01000006_gene2568 7.726e-102 338.0 COG0402@1|root,COG0402@2|Bacteria,1MX34@1224|Proteobacteria,2U0IN@28211|Alphaproteobacteria 28211|Alphaproteobacteria F COG0402 Cytosine deaminase and related metal-dependent hydrolases - - 3.5.4.1 ko:K01485 ko00240,ko00330,ko01100,map00240,map00330,map01100 - R00974,R01411,R02922 RC00074,RC00514,RC00809 ko00000,ko00001,ko01000 - - - Amidohydro_1,Amidohydro_3 CMS1_k127_998777_2 1411123.JQNH01000001_gene718 8.118e-145 464.0 COG0155@1|root,COG0155@2|Bacteria,1MVVB@1224|Proteobacteria,2TRCR@28211|Alphaproteobacteria 28211|Alphaproteobacteria C Sulfite reductase cysI - 1.8.1.2,1.8.7.1 ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R00858,R00859,R03600 RC00065 ko00000,ko00001,ko00002,ko01000 - - - NIR_SIR,NIR_SIR_ferr CMS1_k127_998777_0 1046724.KB889829_gene3063 4.483e-266 829.0 COG0369@1|root,COG0369@2|Bacteria,1MWYV@1224|Proteobacteria,1S126@1236|Gammaproteobacteria,46CWW@72275|Alteromonadaceae 1236|Gammaproteobacteria P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component cysJ GO:0000166,GO:0003674,GO:0003824,GO:0004783,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006790,GO:0008150,GO:0008152,GO:0009337,GO:0009987,GO:0010181,GO:0016491,GO:0016645,GO:0016646,GO:0016651,GO:0016667,GO:0016668,GO:0032553,GO:0032991,GO:0036094,GO:0042602,GO:0043167,GO:0043168,GO:0044237,GO:0044424,GO:0044464,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0055114,GO:0070401,GO:0097159,GO:0097367,GO:1901265,GO:1901363 1.8.1.2 ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R00858 RC00065 ko00000,ko00001,ko00002,ko01000 - - iECO26_1355.ECO26_3835,iECSE_1348.ECSE_3020,iECW_1372.ECW_m2972,iEKO11_1354.EKO11_1004,iEcE24377_1341.EcE24377A_3066,iEcolC_1368.EcolC_0948,iWFL_1372.ECW_m2972 FAD_binding_1,Flavodoxin_1,NAD_binding_1 CMS1_k127_998777_3 1121028.ARQE01000001_gene3048 1.423e-91 308.0 COG0175@1|root,COG0175@2|Bacteria,1MXUR@1224|Proteobacteria,2U5AP@28211|Alphaproteobacteria,2PJRF@255475|Aurantimonadaceae 28211|Alphaproteobacteria EH Reduction of activated sulfate into sulfite cysH - 1.8.4.10,1.8.4.8 ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 M00176 R02021 RC00007,RC02862 ko00000,ko00001,ko00002,ko01000 - - - PAPS_reduct CMS1_k127_998777_1 402881.Plav_0900 1.291e-190 612.0 COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,2TSYI@28211|Alphaproteobacteria,1JPJ8@119043|Rhodobiaceae 28211|Alphaproteobacteria P Phosphate transporter family - - - ko:K03306 - - - - ko00000 2.A.20 - - PHO4 CMS1_k127_998777_5 631454.N177_2395 3.757e-41 158.0 COG0494@1|root,COG0494@2|Bacteria,1MZ5D@1224|Proteobacteria,2VAB5@28211|Alphaproteobacteria,1JQ9B@119043|Rhodobiaceae 28211|Alphaproteobacteria L NUDIX domain - - - - - - - - - - - - NUDIX CMS1_k127_998777_4 1245469.S58_72010 1.038e-72 268.0 COG3206@1|root,COG3206@2|Bacteria,1P8G1@1224|Proteobacteria,2UXP7@28211|Alphaproteobacteria 28211|Alphaproteobacteria M protein involved in exopolysaccharide biosynthesis - - - - - - - - - - - - - ## 3923 queries scanned ## Total time (seconds): 36.47595477104187 ## Rate: 107.55 q/s