## Fri Nov  8 04:00:43 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/bins_4635/CMS1_bin.78.fa -m mmseqs --itype genome -o CMS1_bin.78 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/bins_4635/CMS1_bin.78 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
CMS1_k127_1041075_8	713586.KB900536_gene1648	1.183e-09	64.0	COG0438@1|root,COG0438@2|Bacteria,1QF9A@1224|Proteobacteria,1RMDT@1236|Gammaproteobacteria,1WW1R@135613|Chromatiales	135613|Chromatiales	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS1_k127_1041075_3	472759.Nhal_3385	4.617e-90	305.0	COG0859@1|root,COG0859@2|Bacteria,1MYZA@1224|Proteobacteria,1RPMN@1236|Gammaproteobacteria,1WVVR@135613|Chromatiales	135613|Chromatiales	M	PFAM glycosyl transferase family 9	-	-	-	ko:K02841	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
CMS1_k127_1041075_4	1238182.C882_3197	4.47e-73	257.0	2ECRM@1|root,336P9@2|Bacteria,1P9U9@1224|Proteobacteria,2UW9Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1041075_2	870187.Thini_2476	6.449e-127	420.0	COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,1RN5S@1236|Gammaproteobacteria,45ZQ5@72273|Thiotrichales	72273|Thiotrichales	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
CMS1_k127_1041075_1	713586.KB900536_gene2136	6.804e-170	549.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,1RMH1@1236|Gammaproteobacteria,1WWKE@135613|Chromatiales	135613|Chromatiales	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
CMS1_k127_1041075_5	1410653.JHVC01000020_gene4536	2.375e-24	103.0	COG0759@1|root,COG0759@2|Bacteria,1VEIG@1239|Firmicutes,24QN4@186801|Clostridia,36MJT@31979|Clostridiaceae	186801|Clostridia	S	Could be involved in insertion of integral membrane proteins into the membrane	yidD	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
CMS1_k127_1041075_6	686340.Metal_0002	8.445e-15	81.0	COG0594@1|root,COG0594@2|Bacteria,1MZQE@1224|Proteobacteria,1S90M@1236|Gammaproteobacteria,1XFKR@135618|Methylococcales	135618|Methylococcales	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
CMS1_k127_1041075_7	243233.MCA3034	3.547e-12	66.0	COG0230@1|root,COG0230@2|Bacteria,1NGGS@1224|Proteobacteria,1SGDJ@1236|Gammaproteobacteria,1XFUB@135618|Methylococcales	135618|Methylococcales	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
CMS1_k127_1041075_0	1335757.SPICUR_00005	1.45e-193	612.0	COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,1RNHP@1236|Gammaproteobacteria,1WW6C@135613|Chromatiales	135613|Chromatiales	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
CMS1_k127_1125244_9	1402135.SUH3_00785	4.165e-27	127.0	COG1716@1|root,COG2304@1|root,COG1716@2|Bacteria,COG2304@2|Bacteria,1PI14@1224|Proteobacteria,2V3Y8@28211|Alphaproteobacteria,3ZY9V@60136|Sulfitobacter	28211|Alphaproteobacteria	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,VWA_2
CMS1_k127_1125244_10	1116472.MGMO_5c00020	4.899e-19	93.0	COG3439@1|root,COG3439@2|Bacteria,1NFEI@1224|Proteobacteria,1SCZP@1236|Gammaproteobacteria,1XFC2@135618|Methylococcales	135618|Methylococcales	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
CMS1_k127_1125244_4	323261.Noc_1714	4.391e-44	167.0	COG3034@1|root,COG3034@2|Bacteria,1MXY6@1224|Proteobacteria,1S8WW@1236|Gammaproteobacteria,1X25I@135613|Chromatiales	135613|Chromatiales	S	PFAM ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
CMS1_k127_1125244_5	402626.Rpic_2495	7.979e-42	160.0	COG3038@1|root,COG3038@2|Bacteria,1MZ7X@1224|Proteobacteria,2VV6S@28216|Betaproteobacteria,1K0M6@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Prokaryotic cytochrome b561	-	-	-	ko:K12262	-	-	-	-	ko00000	-	-	-	Ni_hydr_CYTB
CMS1_k127_1125244_2	395493.BegalDRAFT_1681	7.498e-98	337.0	COG4191@1|root,COG4191@2|Bacteria,1RC7X@1224|Proteobacteria,1T4BY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
CMS1_k127_1125244_1	265072.Mfla_1254	3.635e-160	517.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VPRI@28216|Betaproteobacteria,2KKCP@206350|Nitrosomonadales	206350|Nitrosomonadales	T	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS1_k127_1125244_0	1333856.L686_08670	1.335e-167	537.0	COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,1RM9I@1236|Gammaproteobacteria,1Z1D5@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	C	NADH dehydrogenase, FAD-containing subunit	ndh	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
CMS1_k127_1125244_7	395493.BegalDRAFT_2596	2.158e-35	138.0	COG3492@1|root,COG3492@2|Bacteria,1MZ3I@1224|Proteobacteria,1S8SI@1236|Gammaproteobacteria,462VS@72273|Thiotrichales	72273|Thiotrichales	S	Protein of unknown function (DUF1244)	-	-	-	ko:K09948	-	-	-	-	ko00000	-	-	-	DUF1244
CMS1_k127_1125244_6	580332.Slit_0050	3.992e-39	157.0	COG1716@1|root,COG2114@1|root,COG1716@2|Bacteria,COG2114@2|Bacteria,1NAJG@1224|Proteobacteria,2VJW8@28216|Betaproteobacteria,44WHA@713636|Nitrosomonadales	28216|Betaproteobacteria	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,Guanylate_cyc
CMS1_k127_1125244_8	395493.BegalDRAFT_1308	1.759e-30	133.0	COG3735@1|root,COG3735@2|Bacteria,1RBFT@1224|Proteobacteria	1224|Proteobacteria	S	PFAM GumN family protein	-	-	-	ko:K09973	-	-	-	-	ko00000	-	-	-	TraB
CMS1_k127_1125244_3	582744.Msip34_1485	9.64e-65	241.0	COG1538@1|root,COG1538@2|Bacteria,1RFMJ@1224|Proteobacteria,2W2GG@28216|Betaproteobacteria,2KMD4@206350|Nitrosomonadales	206350|Nitrosomonadales	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
CMS1_k127_1125244_11	666681.M301_1538	1.068e-10	71.0	COG0845@1|root,COG0845@2|Bacteria,1R6JG@1224|Proteobacteria,2VUA5@28216|Betaproteobacteria,2KKVF@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1163555_4	754476.Q7A_3035	1.152e-96	326.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,1RMMQ@1236|Gammaproteobacteria,45ZNI@72273|Thiotrichales	72273|Thiotrichales	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
CMS1_k127_1163555_10	765914.ThisiDRAFT_0458	8.986e-55	194.0	COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,1S5XS@1236|Gammaproteobacteria,1WY7E@135613|Chromatiales	135613|Chromatiales	J	PFAM Endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
CMS1_k127_1163555_0	396588.Tgr7_3185	2.658e-264	832.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,1RN3H@1236|Gammaproteobacteria,1WWZ3@135613|Chromatiales	135613|Chromatiales	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
CMS1_k127_1163555_13	2340.JV46_16100	1.557e-20	97.0	COG1758@1|root,COG1758@2|Bacteria,1N6TX@1224|Proteobacteria,1SCSR@1236|Gammaproteobacteria,1J6XN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
CMS1_k127_1163555_8	59196.RICGR_0233	3.297e-58	212.0	COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,1RN09@1236|Gammaproteobacteria,1JCFN@118969|Legionellales	118969|Legionellales	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
CMS1_k127_1163555_5	1123368.AUIS01000026_gene1467	1.105e-81	280.0	COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,1RMAB@1236|Gammaproteobacteria,2NCGF@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Domain of unknown function (DUF1732)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
CMS1_k127_1163555_3	1123401.JHYQ01000009_gene2239	2.671e-103	342.0	COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,1RNTB@1236|Gammaproteobacteria,45ZZN@72273|Thiotrichales	72273|Thiotrichales	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
CMS1_k127_1163555_6	1049564.TevJSym_as00370	1.021e-75	261.0	COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,1S27C@1236|Gammaproteobacteria,1J5SJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035870,GO:0036220,GO:0036222,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046983,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	iEC55989_1330.EC55989_3247,iECO111_1330.ECO111_3702,iECSE_1348.ECSE_3222,iECW_1372.ECW_m3212,iEKO11_1354.EKO11_0774,iEcE24377_1341.EcE24377A_3298,iWFL_1372.ECW_m3212	Ham1p_like
CMS1_k127_1163555_7	472759.Nhal_3859	2.431e-70	244.0	COG4089@1|root,COG4089@2|Bacteria,1MV8K@1224|Proteobacteria,1S5RT@1236|Gammaproteobacteria,1X0MN@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF1614)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1614
CMS1_k127_1163555_12	1379698.RBG1_1C00001G1780	1.472e-20	93.0	COG0826@1|root,COG0826@2|Bacteria,2NS1M@2323|unclassified Bacteria	2|Bacteria	O	peptidase U32	yegQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
CMS1_k127_1163555_1	1123368.AUIS01000007_gene2806	1.164e-177	566.0	COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria,1RQI4@1236|Gammaproteobacteria,2NBZX@225057|Acidithiobacillales	225057|Acidithiobacillales	H	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase,Methyltransf_31
CMS1_k127_1163555_2	1122194.AUHU01000007_gene90	9.785e-119	389.0	COG4301@1|root,COG4301@2|Bacteria,1MUCG@1224|Proteobacteria,1RR44@1236|Gammaproteobacteria,466C6@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Histidine-specific methyltransferase, SAM-dependent	egtD	-	2.1.1.44	ko:K18911	ko00340,map00340	-	R01169	RC00003,RC02308	ko00000,ko00001,ko01000	-	-	-	Methyltransf_33
CMS1_k127_1163555_9	123214.PERMA_1372	4.718e-58	220.0	COG1075@1|root,COG1075@2|Bacteria	2|Bacteria	KLT	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	DUF676,PGAP1
CMS1_k127_1163555_11	91464.S7335_4472	2.593e-45	168.0	COG3440@1|root,COG3440@2|Bacteria,1GPU1@1117|Cyanobacteria,1H3VK@1129|Synechococcus	1117|Cyanobacteria	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_2
CMS1_k127_1186658_22	1297863.APJF01000030_gene983	3.3e-54	196.0	COG1835@1|root,COG1835@2|Bacteria,1N45H@1224|Proteobacteria,2UGVA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
CMS1_k127_1186658_28	1385515.N791_08930	2.226e-08	58.0	2ANYG@1|root,31DZF@2|Bacteria,1QB9H@1224|Proteobacteria,1T6TX@1236|Gammaproteobacteria,1X857@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1186658_4	519989.ECTPHS_06517	2.824e-160	512.0	COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,1RMDH@1236|Gammaproteobacteria,1WWT0@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
CMS1_k127_1186658_7	105559.Nwat_0339	5.039e-127	423.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,1RM8M@1236|Gammaproteobacteria,1WWSQ@135613|Chromatiales	135613|Chromatiales	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
CMS1_k127_1186658_11	1323663.AROI01000004_gene2037	1.573e-93	314.0	COG4535@1|root,COG4535@2|Bacteria,1QTU8@1224|Proteobacteria,1RMKX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Mg2 and Co2 transporter CorC	corC	GO:0001897,GO:0001906,GO:0001907,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009405,GO:0009987,GO:0016020,GO:0019835,GO:0019836,GO:0031640,GO:0035821,GO:0044003,GO:0044004,GO:0044179,GO:0044364,GO:0044403,GO:0044419,GO:0044464,GO:0044764,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071944	-	ko:K06189	-	-	-	-	ko00000,ko02000	9.A.40.1.2	-	-	CBS,CorC_HlyC
CMS1_k127_1186658_24	1279017.AQYJ01000024_gene977	2.332e-40	154.0	COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,1S6BS@1236|Gammaproteobacteria,467I5@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
CMS1_k127_1186658_5	1249627.D779_0119	3.376e-140	452.0	COG1702@1|root,COG1702@2|Bacteria,1MVDV@1224|Proteobacteria,1RP2Y@1236|Gammaproteobacteria,1WW3U@135613|Chromatiales	135613|Chromatiales	T	PFAM PhoH family protein	-	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
CMS1_k127_1186658_3	1122134.KB893650_gene93	8.864e-208	654.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,1RMD8@1236|Gammaproteobacteria,1XHQS@135619|Oceanospirillales	135619|Oceanospirillales	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
CMS1_k127_1186658_13	338963.Pcar_0306	1.379e-87	297.0	COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,42PH4@68525|delta/epsilon subdivisions,2WME5@28221|Deltaproteobacteria,43T1N@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Conserved TM helix	-	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel,TM_helix
CMS1_k127_1186658_25	519989.ECTPHS_04004	4.855e-29	124.0	COG4067@1|root,COG4067@2|Bacteria,1N7Y2@1224|Proteobacteria,1SARP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	protein conserved in archaea	-	-	-	-	-	-	-	-	-	-	-	-	Zn_protease
CMS1_k127_1186658_8	472759.Nhal_2058	1.221e-121	409.0	COG1305@1|root,COG1305@2|Bacteria,1MVV3@1224|Proteobacteria,1RRIA@1236|Gammaproteobacteria,1X0CC@135613|Chromatiales	135613|Chromatiales	E	7 transmembrane helices usually fused to an inactive transglutaminase	-	-	-	-	-	-	-	-	-	-	-	-	7TM_transglut,Transglut_i_TM
CMS1_k127_1186658_9	1232437.KL662047_gene5143	5.571e-115	378.0	COG0189@1|root,COG0189@2|Bacteria,1MVDU@1224|Proteobacteria,42MVH@68525|delta/epsilon subdivisions,2WMHB@28221|Deltaproteobacteria,2MME3@213118|Desulfobacterales	28221|Deltaproteobacteria	HJ	Sugar-transfer associated ATP-grasp	-	-	-	-	-	-	-	-	-	-	-	-	ATPgrasp_ST
CMS1_k127_1186658_10	391615.ABSJ01000027_gene186	2.003e-96	331.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,1S1T4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,cNMP_binding
CMS1_k127_1186658_20	472759.Nhal_2564	2.609e-57	203.0	COG3019@1|root,COG3019@2|Bacteria,1MZ9V@1224|Proteobacteria,1S9CQ@1236|Gammaproteobacteria,1WZ4Y@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function, DUF	-	-	-	-	-	-	-	-	-	-	-	-	DUF411
CMS1_k127_1186658_21	472759.Nhal_2115	1.18e-55	199.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,1S7QZ@1236|Gammaproteobacteria,1WYRM@135613|Chromatiales	135613|Chromatiales	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
CMS1_k127_1186658_0	338969.Rfer_0832	1.735e-289	899.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,2VH14@28216|Betaproteobacteria,4ABI0@80864|Comamonadaceae	28216|Betaproteobacteria	O	Heat shock 70 kDa protein	-	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
CMS1_k127_1186658_6	748247.AZKH_1502	1.196e-136	444.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,2VHEH@28216|Betaproteobacteria,2KUWF@206389|Rhodocyclales	28216|Betaproteobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
CMS1_k127_1186658_17	555088.DealDRAFT_3009	1.753e-64	229.0	COG0500@1|root,COG2226@2|Bacteria,1V7TR@1239|Firmicutes,24Q0B@186801|Clostridia	186801|Clostridia	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS1_k127_1186658_19	519989.ECTPHS_10004	1.765e-60	212.0	COG1666@1|root,COG1666@2|Bacteria,1RDTF@1224|Proteobacteria,1S3RU@1236|Gammaproteobacteria,1WXZ5@135613|Chromatiales	135613|Chromatiales	S	Belongs to the UPF0234 family	-	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
CMS1_k127_1186658_26	1132855.KB913035_gene1131	6.57e-11	67.0	2CHAX@1|root,32ZC9@2|Bacteria,1N6X2@1224|Proteobacteria,2VW2I@28216|Betaproteobacteria,2KN5V@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Protein of unknown function (DUF3301)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3301
CMS1_k127_1186658_12	631362.Thi970DRAFT_01013	4.245e-93	317.0	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,1RNMZ@1236|Gammaproteobacteria,1WWAK@135613|Chromatiales	135613|Chromatiales	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
CMS1_k127_1186658_1	1116472.MGMO_11c00490	1.622e-269	850.0	COG4774@1|root,COG4774@2|Bacteria,1QW60@1224|Proteobacteria,1T58A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
CMS1_k127_1186658_14	580332.Slit_2927	1.429e-87	300.0	COG3511@1|root,COG3511@2|Bacteria,1RCY1@1224|Proteobacteria,2WEZW@28216|Betaproteobacteria,44WCM@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Phosphoesterase
CMS1_k127_1186658_23	449447.MAE_40030	1.234e-53	200.0	COG0463@1|root,COG0463@2|Bacteria,1G03Y@1117|Cyanobacteria	1117|Cyanobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
CMS1_k127_1186658_18	118163.Ple7327_3829	5.113e-61	218.0	COG0500@1|root,COG0500@2|Bacteria,1GQU0@1117|Cyanobacteria	1117|Cyanobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
CMS1_k127_1186658_16	1173021.ALWA01000012_gene1164	1.082e-71	267.0	COG2199@1|root,COG2202@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria,1FZWU@1117|Cyanobacteria	1117|Cyanobacteria	T	Diguanylate cyclase with PAS PAC and GAF sensors	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,GGDEF,PAS,PAS_3,PAS_9
CMS1_k127_1186658_15	323261.Noc_0350	1.274e-81	287.0	COG2206@1|root,COG2206@2|Bacteria,1MW7F@1224|Proteobacteria,1RPEZ@1236|Gammaproteobacteria,1WX4U@135613|Chromatiales	135613|Chromatiales	T	PFAM Metal-dependent phosphohydrolase, HD	-	-	-	-	-	-	-	-	-	-	-	-	DUF3391,HD_5
CMS1_k127_1186658_29	1207075.PputUW4_03589	3.862e-07	59.0	2DCQG@1|root,2ZEY9@2|Bacteria,1P8EW@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1186658_2	517417.Cpar_1700	1.679e-217	682.0	COG3004@1|root,COG3004@2|Bacteria,1FDWE@1090|Chlorobi	1090|Chlorobi	P	) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
CMS1_k127_1186658_27	1096769.Pelub83DRAFT_0422	1.04e-08	62.0	2DCSA@1|root,2ZF5F@2|Bacteria,1P4AI@1224|Proteobacteria,2UWWJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1186658_31	195250.CM001776_gene1194	0.000134	44.0	COG4974@1|root,COG4974@2|Bacteria,1G67I@1117|Cyanobacteria	1117|Cyanobacteria	L	Phage integrase family	-	-	-	ko:K07358	-	-	-	-	ko00000	-	-	-	Phage_integrase
CMS1_k127_1186658_30	144197.XP_008293913.1	7.672e-05	54.0	KOG3544@1|root,KOG3544@2759|Eukaryota,38DGH@33154|Opisthokonta,3BA28@33208|Metazoa,3CSNV@33213|Bilateria,48QB3@7711|Chordata,48Y2Q@7742|Vertebrata,49RXY@7898|Actinopterygii	33208|Metazoa	W	collagen	COL6A3	GO:0005575,GO:0005576,GO:0005581,GO:0005589,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005788,GO:0007275,GO:0007517,GO:0008150,GO:0009987,GO:0012505,GO:0016043,GO:0030198,GO:0031012,GO:0031974,GO:0032501,GO:0032502,GO:0032991,GO:0043062,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044421,GO:0044422,GO:0044424,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0048513,GO:0048731,GO:0048856,GO:0061061,GO:0070013,GO:0071840,GO:0098647,GO:0099080,GO:0099081,GO:0099512	-	ko:K06238	ko04151,ko04510,ko04512,ko04974,ko05165,map04151,map04510,map04512,map04974,map05165	-	-	-	ko00000,ko00001,ko00536,ko04147,ko04516	-	-	-	Collagen,Kunitz_BPTI,VWA,fn3
CMS1_k127_1200752_2	1415756.JQMY01000001_gene613	1.69e-34	149.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria,2PF1G@252301|Oceanicola	28211|Alphaproteobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
CMS1_k127_1200752_0	765911.Thivi_3619	0.0	1352.0	COG0204@1|root,COG0318@1|root,COG0477@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,COG0477@2|Bacteria,1MWDY@1224|Proteobacteria,1RRXF@1236|Gammaproteobacteria,1WXH7@135613|Chromatiales	135613|Chromatiales	I	SMART Phospholipid glycerol acyltransferase	-	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase,MFS_1
CMS1_k127_1200752_1	1117647.M5M_10575	3.987e-288	891.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPWS@1236|Gammaproteobacteria,1J503@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	COG0488 ATPase components of ABC transporters with duplicated ATPase domains	yjjK	GO:0003674,GO:0003824,GO:0005488,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113	3.6.3.25	ko:K06020	-	-	-	-	ko00000,ko01000	-	-	-	ABC_tran,ABC_tran_Xtn
CMS1_k127_1203277_1	1298867.AUES01000002_gene1353	1.901e-184	585.0	COG1055@1|root,COG1055@2|Bacteria,1MUH8@1224|Proteobacteria,2U0BW@28211|Alphaproteobacteria,3JU7T@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Sodium proton antiporter, NhaD family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1203277_0	1218084.BBJK01000013_gene1437	9.66e-314	968.0	COG1620@1|root,COG1620@2|Bacteria,1MV13@1224|Proteobacteria,2VHJN@28216|Betaproteobacteria,1K1HD@119060|Burkholderiaceae	28216|Betaproteobacteria	C	permease	lldP	-	-	ko:K03303	-	-	-	-	ko00000,ko02000	2.A.14	-	-	Lactate_perm
CMS1_k127_1203277_6	314266.SKA58_16093	1.047e-18	96.0	COG1595@1|root,COG1595@2|Bacteria,1RIBP@1224|Proteobacteria,2U9AD@28211|Alphaproteobacteria,2KA1W@204457|Sphingomonadales	204457|Sphingomonadales	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1203277_5	713586.KB900536_gene1610	8.736e-25	104.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Cold shock	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
CMS1_k127_1203277_7	1198232.CYCME_2433	1.581e-10	64.0	2DDNE@1|root,2ZINX@2|Bacteria,1PAK4@1224|Proteobacteria,1STKN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1203277_2	1286106.MPL1_05037	1.306e-125	406.0	COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,1RN2H@1236|Gammaproteobacteria,45ZYE@72273|Thiotrichales	72273|Thiotrichales	D	Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system	ttcA	-	-	ko:K14058	-	-	-	-	ko00000,ko03016	-	-	-	ATP_bind_3
CMS1_k127_1203277_4	765911.Thivi_1150	1.688e-73	253.0	COG1994@1|root,COG1994@2|Bacteria,1NSFF@1224|Proteobacteria,1S4N8@1236|Gammaproteobacteria,1WWRR@135613|Chromatiales	135613|Chromatiales	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
CMS1_k127_1203277_3	207954.MED92_02106	2.206e-77	263.0	COG3264@1|root,COG3264@2|Bacteria,1QUBW@1224|Proteobacteria,1T1SF@1236|Gammaproteobacteria,1XRS5@135619|Oceanospirillales	135619|Oceanospirillales	M	mechanosensitive ion channel	-	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel,TM_helix
CMS1_k127_1333672_4	1415780.JPOG01000001_gene267	2.301e-11	69.0	2B3X8@1|root,31WM6@2|Bacteria,1RFUV@1224|Proteobacteria,1RNAH@1236|Gammaproteobacteria,1X5HH@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF3999)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3999
CMS1_k127_1333672_0	1121405.dsmv_0222	2.292e-236	760.0	COG5373@1|root,COG5373@2|Bacteria,1N08V@1224|Proteobacteria,42NMF@68525|delta/epsilon subdivisions,2WIJ2@28221|Deltaproteobacteria,2MIRD@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Predicted membrane protein (DUF2339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
CMS1_k127_1333672_2	998674.ATTE01000001_gene3691	1.446e-110	365.0	COG0583@1|root,COG0583@2|Bacteria,1MVA1@1224|Proteobacteria,1RPAJ@1236|Gammaproteobacteria,460V0@72273|Thiotrichales	72273|Thiotrichales	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	ko:K04761	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
CMS1_k127_1333672_3	977880.RALTA_A2583	3.352e-72	248.0	COG0783@1|root,COG0783@2|Bacteria,1RAC5@1224|Proteobacteria,2VHJI@28216|Betaproteobacteria,1K08S@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Belongs to the Dps family	dps	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
CMS1_k127_1333672_1	870187.Thini_3072	1.517e-121	395.0	COG0678@1|root,COG0695@1|root,COG0678@2|Bacteria,COG0695@2|Bacteria,1MU0H@1224|Proteobacteria,1RRFB@1236|Gammaproteobacteria,45ZZT@72273|Thiotrichales	72273|Thiotrichales	O	Glutaredoxin	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	Glutaredoxin,Redoxin
CMS1_k127_1372569_3	1458275.AZ34_12805	4.721e-27	120.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,1MWVZ@1224|Proteobacteria,2WEGS@28216|Betaproteobacteria	28216|Betaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	Pkinase
CMS1_k127_1372569_2	1122212.AULO01000014_gene1158	1.624e-70	247.0	COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,1S4U5@1236|Gammaproteobacteria,1XJZ6@135619|Oceanospirillales	135619|Oceanospirillales	T	serine threonine protein phosphatase	-	-	3.1.3.16	ko:K01090,ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
CMS1_k127_1372569_1	1122212.AULO01000014_gene1157	2.701e-97	326.0	COG1716@1|root,COG2114@1|root,COG1716@2|Bacteria,COG2114@2|Bacteria,1NAJG@1224|Proteobacteria,1RYIU@1236|Gammaproteobacteria,1XKCX@135619|Oceanospirillales	135619|Oceanospirillales	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Guanylate_cyc
CMS1_k127_1372569_4	1499968.TCA2_4816	3.816e-09	68.0	COG0760@1|root,COG0760@2|Bacteria,1V2D1@1239|Firmicutes,4HFU5@91061|Bacilli,276F7@186822|Paenibacillaceae	91061|Bacilli	O	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins	prsA	-	5.2.1.8	ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,Rotamase_3,SurA_N_3
CMS1_k127_1372569_0	1122212.AULO01000009_gene661	4.073e-121	411.0	COG2831@1|root,COG2831@2|Bacteria,1MWEC@1224|Proteobacteria,1RYVX@1236|Gammaproteobacteria,1XKPD@135619|Oceanospirillales	135619|Oceanospirillales	U	Haemolysin secretion/activation protein ShlB/FhaC/HecB	-	-	-	-	-	-	-	-	-	-	-	-	POTRA_2,ShlB
CMS1_k127_1456899_13	339670.Bamb_1110	0.0003215	45.0	COG4679@1|root,COG4679@2|Bacteria,1MZC9@1224|Proteobacteria,2VSDW@28216|Betaproteobacteria,1K7R9@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Phage derived protein Gp49-like (DUF891)	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
CMS1_k127_1456899_12	1280696.ATVY01000069_gene1813	0.0002458	47.0	COG3620@1|root,COG3620@2|Bacteria,1V77U@1239|Firmicutes,24UZE@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
CMS1_k127_1456899_6	1232683.ADIMK_1068	9.972e-92	310.0	COG0476@1|root,COG0476@2|Bacteria,1MW7H@1224|Proteobacteria,1RPJ3@1236|Gammaproteobacteria,466BQ@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2	moeB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0061605,GO:0070566,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.73,2.7.7.80	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	iECIAI1_1343.ECIAI1_0865,iECW_1372.ECW_m0884,iEKO11_1354.EKO11_3059,iETEC_1333.ETEC_0893,iEcE24377_1341.EcE24377A_0897,iEcSMS35_1347.EcSMS35_0851,iWFL_1372.ECW_m0884	ThiF
CMS1_k127_1456899_7	243924.LT42_22880	2.497e-72	255.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,1RNGK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006464,GO:0006479,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0010468,GO:0016043,GO:0016740,GO:0016741,GO:0018364,GO:0019222,GO:0019538,GO:0022411,GO:0032259,GO:0032984,GO:0034641,GO:0034645,GO:0036009,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043414,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0140096,GO:1901564,GO:1901566,GO:1901576	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
CMS1_k127_1456899_1	870187.Thini_1102	9.92e-159	509.0	COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,1RM7Q@1236|Gammaproteobacteria,4604F@72273|Thiotrichales	72273|Thiotrichales	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
CMS1_k127_1456899_3	765912.Thimo_3131	2.401e-147	478.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,1RNQ8@1236|Gammaproteobacteria,1WX0A@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
CMS1_k127_1456899_4	472759.Nhal_3926	4.663e-124	418.0	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,1RQIX@1236|Gammaproteobacteria,1WWY6@135613|Chromatiales	135613|Chromatiales	U	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
CMS1_k127_1456899_10	754477.Q7C_2097	7.225e-39	152.0	COG3017@1|root,COG3017@2|Bacteria,1N02T@1224|Proteobacteria,1S91E@1236|Gammaproteobacteria,4617Y@72273|Thiotrichales	72273|Thiotrichales	M	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein	lolB	-	-	ko:K02494	-	-	-	-	ko00000	-	-	-	LolB
CMS1_k127_1456899_5	396588.Tgr7_0526	1.259e-101	338.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,1RP23@1236|Gammaproteobacteria,1WX6F@135613|Chromatiales	135613|Chromatiales	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
CMS1_k127_1456899_11	34506.g6239	5.159e-05	46.0	COG0654@1|root,KOG3855@2759|Eukaryota,38FN2@33154|Opisthokonta,3BAK6@33208|Metazoa,3CYXR@33213|Bilateria,40CPH@6231|Nematoda,1KVIW@119089|Chromadorea,40V9S@6236|Rhabditida	33208|Metazoa	CH	FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3- polyprenyl-4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin ferredoxin reductase system to COQ6	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
CMS1_k127_1456899_2	395493.BegalDRAFT_2511	7.943e-148	473.0	COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,1RMUC@1236|Gammaproteobacteria,45ZR2@72273|Thiotrichales	72273|Thiotrichales	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
CMS1_k127_1456899_8	396588.Tgr7_0528	2.724e-68	240.0	COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,1S46A@1236|Gammaproteobacteria,1WYEN@135613|Chromatiales	135613|Chromatiales	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
CMS1_k127_1456899_9	90813.JQMT01000001_gene287	9.644e-66	230.0	COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,1RPK3@1236|Gammaproteobacteria,460KW@72273|Thiotrichales	72273|Thiotrichales	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
CMS1_k127_1456899_0	1249627.D779_0693	4.294e-161	514.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,1RMBI@1236|Gammaproteobacteria,1WWWF@135613|Chromatiales	135613|Chromatiales	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
CMS1_k127_1525765_0	1121939.L861_14950	5.966e-112	378.0	COG0277@1|root,COG0277@2|Bacteria,1MUPW@1224|Proteobacteria,1RRDD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
CMS1_k127_1526957_4	579405.Dd703_2419	2.127e-13	72.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,2JBP9@204037|Dickeya	1236|Gammaproteobacteria	JKL	DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA	rhlE	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0006996,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0042254,GO:0042255,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0065003,GO:0070035,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0140098,GO:1901360	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
CMS1_k127_1526957_3	2340.JV46_19500	2.402e-22	99.0	2FG0M@1|root,347XB@2|Bacteria,1P191@1224|Proteobacteria,1SSBB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1488)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1488
CMS1_k127_1526957_2	1165096.ARWF01000001_gene2279	1.525e-23	102.0	COG0672@1|root,COG0672@2|Bacteria	2|Bacteria	P	high-affinity ferrous iron transmembrane transporter activity	-	-	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	DUF2318,FTR1
CMS1_k127_1526957_0	1121918.ARWE01000001_gene564	1.04e-82	283.0	COG4096@1|root,COG4096@2|Bacteria,1QTS7@1224|Proteobacteria,42MXU@68525|delta/epsilon subdivisions,2WK28@28221|Deltaproteobacteria,43SUR@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	EcoEI R protein C-terminal	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	EcoEI_R_C,HSDR_N,Helicase_C,ResIII
CMS1_k127_1526957_1	91464.S7335_4472	7.445e-33	129.0	COG3440@1|root,COG3440@2|Bacteria,1GPU1@1117|Cyanobacteria,1H3VK@1129|Synechococcus	1117|Cyanobacteria	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_2
CMS1_k127_1563515_32	414684.RC1_3446	3.531e-20	94.0	COG3203@1|root,COG3203@2|Bacteria,1MXEB@1224|Proteobacteria,2U8WW@28211|Alphaproteobacteria,2JSKJ@204441|Rhodospirillales	204441|Rhodospirillales	M	Protein of unknown function (DUF1302)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1302
CMS1_k127_1563515_18	391615.ABSJ01000027_gene186	1.159e-110	374.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,1S1T4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,cNMP_binding
CMS1_k127_1563515_29	1205753.A989_04778	2.378e-44	165.0	COG2905@1|root,COG2905@2|Bacteria,1QTTR@1224|Proteobacteria,1T1K1@1236|Gammaproteobacteria,1X6ZX@135614|Xanthomonadales	135614|Xanthomonadales	T	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
CMS1_k127_1563515_11	1283300.ATXB01000001_gene2287	6.45e-146	479.0	COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,1RNIT@1236|Gammaproteobacteria,1XEDN@135618|Methylococcales	135618|Methylococcales	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
CMS1_k127_1563515_19	1122604.JONR01000006_gene2745	3.684e-105	356.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,1S1T4@1236|Gammaproteobacteria,1XCD5@135614|Xanthomonadales	135614|Xanthomonadales	KLT	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,cNMP_binding
CMS1_k127_1563515_22	211165.AJLN01000081_gene933	1.135e-82	282.0	COG1213@1|root,COG1213@2|Bacteria	2|Bacteria	M	nucleotidyl transferase	-	-	2.7.7.74	ko:K07281	ko00562,map00562	-	R09669	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3,NTP_transferase
CMS1_k127_1563515_2	211165.AJLN01000081_gene934	5.481e-237	745.0	COG1213@1|root,COG2513@1|root,COG1213@2|Bacteria,COG2513@2|Bacteria,1G4G0@1117|Cyanobacteria	1117|Cyanobacteria	GM	Phosphoenolpyruvate phosphomutase	-	-	5.4.2.9	ko:K01841	ko00440,ko01100,ko01120,ko01130,map00440,map01100,map01120,map01130	-	R00661	RC02792	ko00000,ko00001,ko01000	-	-	-	CTP_transf_like,NTP_transf_3,PEP_mutase
CMS1_k127_1563515_12	211165.AJLN01000081_gene939	3.159e-144	468.0	COG0028@1|root,COG4032@1|root,COG0028@2|Bacteria,COG4032@2|Bacteria,1G36U@1117|Cyanobacteria	1117|Cyanobacteria	EH	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	-	-	4.1.1.82	ko:K09459	ko00440,ko01100,ko01120,ko01130,map00440,map01100,map01120,map01130	-	R04053	RC00506	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_N
CMS1_k127_1563515_15	211165.AJLN01000081_gene941	7.84e-128	424.0	COG0075@1|root,COG0075@2|Bacteria,1G2P6@1117|Cyanobacteria,1JKQY@1189|Stigonemataceae	2|Bacteria	E	Aminotransferase class-V	phnW	-	2.6.1.37	ko:K03430	ko00440,ko01100,ko01120,map00440,map01100,map01120	-	R04152	RC00008,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_5
CMS1_k127_1563515_1	557598.LHK_02324	1.055e-278	869.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,2VHXG@28216|Betaproteobacteria,2KPGU@206351|Neisseriales	206351|Neisseriales	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
CMS1_k127_1563515_8	472759.Nhal_1239	3.203e-181	580.0	COG0535@1|root,COG0535@2|Bacteria,1MXM1@1224|Proteobacteria,1RNQ1@1236|Gammaproteobacteria,1X06Z@135613|Chromatiales	135613|Chromatiales	S	Radical SAM domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3463,Radical_SAM
CMS1_k127_1563515_17	472759.Nhal_1238	6.713e-117	388.0	COG1215@1|root,COG1215@2|Bacteria,1MW1E@1224|Proteobacteria,1RZY2@1236|Gammaproteobacteria,1X091@135613|Chromatiales	135613|Chromatiales	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
CMS1_k127_1563515_30	243233.MCA0806	2.933e-38	152.0	COG2854@1|root,COG2854@2|Bacteria,1N275@1224|Proteobacteria,1SB2V@1236|Gammaproteobacteria,1XE7V@135618|Methylococcales	135618|Methylococcales	Q	PFAM Toluene tolerance	-	-	-	ko:K07323	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	MlaC
CMS1_k127_1563515_24	228410.NE1169	1.792e-66	236.0	COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,2VQ97@28216|Betaproteobacteria,371T4@32003|Nitrosomonadales	28216|Betaproteobacteria	M	MlaA lipoprotein	vacJ	-	-	ko:K04754	-	-	-	-	ko00000	-	-	-	MlaA
CMS1_k127_1563515_13	1123368.AUIS01000005_gene483	1.344e-138	451.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,1RPAB@1236|Gammaproteobacteria,2NBWP@225057|Acidithiobacillales	225057|Acidithiobacillales	C	4Fe-4S dicluster domain	glcF	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_7
CMS1_k127_1563515_16	1123368.AUIS01000005_gene484	4.864e-125	410.0	COG0277@1|root,COG0277@2|Bacteria,1MVYV@1224|Proteobacteria,1RN4G@1236|Gammaproteobacteria,2NC9T@225057|Acidithiobacillales	225057|Acidithiobacillales	C	FAD binding domain	glcE	-	-	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	FAD-oxidase_C,FAD_binding_4
CMS1_k127_1563515_4	396588.Tgr7_2037	1.773e-215	677.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,1RQX2@1236|Gammaproteobacteria,1WWEY@135613|Chromatiales	135613|Chromatiales	C	FAD linked oxidase	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
CMS1_k127_1563515_6	42565.FP66_11215	8.23e-192	612.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMIW@1236|Gammaproteobacteria,1XI2S@135619|Oceanospirillales	135619|Oceanospirillales	J	Involved in the processing of the 5'end of 16S rRNA	-	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
CMS1_k127_1563515_21	765913.ThidrDRAFT_2322	3.475e-94	349.0	COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,1RNUK@1236|Gammaproteobacteria,1WXQJ@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_2,DUF3971
CMS1_k127_1563515_26	1485544.JQKP01000007_gene1954	1.982e-49	181.0	COG1051@1|root,COG1051@2|Bacteria,1N03W@1224|Proteobacteria,2VRC0@28216|Betaproteobacteria,44VT0@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Belongs to the Nudix hydrolase family. NudJ subfamily	nudJ	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS1_k127_1563515_10	1198232.CYCME_1257	5.174e-150	482.0	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,1RMAK@1236|Gammaproteobacteria,45ZSN@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
CMS1_k127_1563515_23	1283300.ATXB01000001_gene829	9.628e-78	265.0	COG2865@1|root,COG2865@2|Bacteria,1RDDZ@1224|Proteobacteria,1S277@1236|Gammaproteobacteria,1XGH5@135618|Methylococcales	135618|Methylococcales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1563515_0	1500890.JQNL01000001_gene3238	0.0	1244.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,1RN5I@1236|Gammaproteobacteria,1X3SP@135614|Xanthomonadales	135614|Xanthomonadales	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
CMS1_k127_1563515_25	666681.M301_0836	1.318e-50	181.0	COG1942@1|root,COG1942@2|Bacteria,1RHA5@1224|Proteobacteria,2VRCH@28216|Betaproteobacteria	28216|Betaproteobacteria	S	tautomerase	-	-	-	-	-	-	-	-	-	-	-	-	Tautomerase_2
CMS1_k127_1563515_33	1538295.JY96_18615	2.837e-08	57.0	COG2331@1|root,COG2331@2|Bacteria,1N8DC@1224|Proteobacteria,2VWBQ@28216|Betaproteobacteria,1KMIH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
CMS1_k127_1563515_31	1415780.JPOG01000001_gene2978	7.834e-30	125.0	COG1917@1|root,COG1917@2|Bacteria,1PBNJ@1224|Proteobacteria,1STIU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS1_k127_1563515_27	1173028.ANKO01000081_gene3815	4.518e-46	169.0	COG3809@1|root,COG3809@2|Bacteria,1G6XN@1117|Cyanobacteria,1HBMB@1150|Oscillatoriales	1117|Cyanobacteria	S	Transcription factor zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-TFIIB
CMS1_k127_1563515_7	159087.Daro_3904	8.653e-185	602.0	COG0659@1|root,COG0664@1|root,COG0659@2|Bacteria,COG0664@2|Bacteria,1MVWV@1224|Proteobacteria,2VN25@28216|Betaproteobacteria,2KXUF@206389|Rhodocyclales	206389|Rhodocyclales	P	Sulfate permease family	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp,cNMP_binding
CMS1_k127_1563515_9	472759.Nhal_1512	1.556e-173	550.0	COG1897@1|root,COG1897@2|Bacteria,1MV64@1224|Proteobacteria,1RM7T@1236|Gammaproteobacteria,1WWUS@135613|Chromatiales	135613|Chromatiales	E	Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine	metAS	-	2.3.1.46	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	M00017	R01777	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	HTS
CMS1_k127_1563515_14	472759.Nhal_1513	1.078e-129	419.0	COG1132@1|root,COG1132@2|Bacteria,1MX5V@1224|Proteobacteria,1RY02@1236|Gammaproteobacteria,1WXG2@135613|Chromatiales	135613|Chromatiales	V	(ABC) transporter	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1563515_5	760117.JN27_04655	1.044e-200	632.0	COG2224@1|root,COG2224@2|Bacteria,1MWIF@1224|Proteobacteria,2VHWS@28216|Betaproteobacteria,472G8@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Isocitrate lyase	aceA	-	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	ICL
CMS1_k127_1563515_3	521098.Aaci_2530	1.929e-222	702.0	COG2225@1|root,COG2225@2|Bacteria,1TPE8@1239|Firmicutes,4H9ST@91061|Bacilli,279F3@186823|Alicyclobacillaceae	91061|Bacilli	C	Malate synthase	aceB	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
CMS1_k127_1563515_28	519989.ECTPHS_03192	3.658e-45	165.0	COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,1S8Z7@1236|Gammaproteobacteria,1WYBV@135613|Chromatiales	135613|Chromatiales	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
CMS1_k127_1563515_20	395493.BegalDRAFT_1677	4.296e-97	322.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,1RMH3@1236|Gammaproteobacteria,45ZV1@72273|Thiotrichales	72273|Thiotrichales	O	ATP-dependent Clp protease ATP-binding subunit ClpA	-	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
CMS1_k127_1578102_2	981384.AEYW01000006_gene2228	1.909e-11	74.0	COG0265@1|root,COG1716@1|root,COG0265@2|Bacteria,COG1716@2|Bacteria,1Q7H1@1224|Proteobacteria,2VDNE@28211|Alphaproteobacteria,4ND4E@97050|Ruegeria	28211|Alphaproteobacteria	OT	Trypsin-like peptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
CMS1_k127_1578102_0	572477.Alvin_0820	5.643e-193	610.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,1RNS4@1236|Gammaproteobacteria,1WW3A@135613|Chromatiales	135613|Chromatiales	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
CMS1_k127_1578102_1	713586.KB900536_gene2533	4.91e-174	556.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,1RMWS@1236|Gammaproteobacteria,1WWGN@135613|Chromatiales	135613|Chromatiales	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
CMS1_k127_1603977_10	472759.Nhal_1236	1.387e-77	272.0	COG1033@1|root,COG1033@2|Bacteria,1QW3H@1224|Proteobacteria,1RZA3@1236|Gammaproteobacteria,1X2NT@135613|Chromatiales	135613|Chromatiales	S	TIGRFAM hopanoid biosynthesis associated RND transporter like protein HpnN	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
CMS1_k127_1603977_9	323261.Noc_1391	1.521e-93	313.0	COG5285@1|root,COG5285@2|Bacteria,1N31I@1224|Proteobacteria,1SDAB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	1.14.11.46	ko:K21195	ko00440,map00440	-	R10724	RC01107	ko00000,ko00001,ko01000	-	-	-	PhyH
CMS1_k127_1603977_12	472759.Nhal_1308	6.046e-41	161.0	COG0775@1|root,COG0775@2|Bacteria,1MY5S@1224|Proteobacteria,1RNSF@1236|Gammaproteobacteria,1WZQ1@135613|Chromatiales	135613|Chromatiales	F	other phosphorylase family 1	-	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
CMS1_k127_1603977_1	228410.NE1168	1.083e-260	818.0	COG1657@1|root,COG1657@2|Bacteria,1MUIP@1224|Proteobacteria,2VPI8@28216|Betaproteobacteria,372CD@32003|Nitrosomonadales	28216|Betaproteobacteria	I	PFAM Prenyltransferase squalene oxidase	shc	-	4.2.1.129,5.4.99.17	ko:K06045	ko00909,ko01110,map00909,map01110	-	R07322,R07323	RC01850,RC01851	ko00000,ko00001,ko01000	-	-	-	SQHop_cyclase_C,SQHop_cyclase_N
CMS1_k127_1603977_3	153948.NAL212_2368	1.393e-150	484.0	COG1562@1|root,COG1562@2|Bacteria,1R4ZD@1224|Proteobacteria,2VQS1@28216|Betaproteobacteria,371ZA@32003|Nitrosomonadales	28216|Betaproteobacteria	I	PFAM Squalene phytoene synthase	fdfT	-	2.5.1.21	ko:K00801	ko00100,ko00909,ko01100,ko01110,ko01130,map00100,map00909,map01100,map01110,map01130	-	R00702,R02872,R06223	RC00362,RC00796,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	SQS_PSY
CMS1_k127_1603977_18	224911.27350827	7.625e-07	51.0	2F0SV@1|root,33TUX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1603977_7	472759.Nhal_0076	4.985e-122	402.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,1RPR7@1236|Gammaproteobacteria,1WWNM@135613|Chromatiales	135613|Chromatiales	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
CMS1_k127_1603977_14	1286106.MPL1_09135	5.767e-34	138.0	COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,1S5VB@1236|Gammaproteobacteria,460ZR@72273|Thiotrichales	72273|Thiotrichales	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
CMS1_k127_1603977_13	1283284.AZUK01000001_gene739	5.833e-38	145.0	COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,1S8R2@1236|Gammaproteobacteria,1Y5U9@135624|Aeromonadales	135624|Aeromonadales	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
CMS1_k127_1603977_6	626887.J057_14570	5.042e-133	434.0	COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,1RMFQ@1236|Gammaproteobacteria,4647H@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0007059,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0022607,GO:0022611,GO:0022613,GO:0022618,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0043021,GO:0043023,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0065003,GO:0065007,GO:0070925,GO:0071826,GO:0071840,GO:0090069,GO:0090071,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
CMS1_k127_1603977_4	472759.Nhal_0072	2.041e-146	473.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,1RM7X@1236|Gammaproteobacteria,1WWMC@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
CMS1_k127_1603977_15	1537994.JQFW01000028_gene23	5.643e-23	100.0	COG0268@1|root,COG0268@2|Bacteria,1MZ94@1224|Proteobacteria,1S9AI@1236|Gammaproteobacteria,467QN@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Binds directly to 16S ribosomal RNA	rpsT	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
CMS1_k127_1603977_2	472759.Nhal_0070	7.835e-174	559.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,1RMXX@1236|Gammaproteobacteria,1WWAE@135613|Chromatiales	135613|Chromatiales	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
CMS1_k127_1603977_8	1122194.AUHU01000017_gene1756	1.121e-97	328.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,1RN44@1236|Gammaproteobacteria,464EI@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	Belongs to the ribF family	ribF	GO:0003674,GO:0003824,GO:0003919,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008531,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0044237,GO:0070566	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iETEC_1333.ETEC_0025,iJN746.PP_0602	FAD_syn,Flavokinase
CMS1_k127_1603977_0	472759.Nhal_0903	0.0	1276.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,1RMTF@1236|Gammaproteobacteria,1WXI8@135613|Chromatiales	135613|Chromatiales	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
CMS1_k127_1603977_11	472759.Nhal_0905	1.807e-55	197.0	COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,1S60E@1236|Gammaproteobacteria,1WY9G@135613|Chromatiales	135613|Chromatiales	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
CMS1_k127_1603977_5	743720.Psefu_0744	6.347e-143	459.0	COG0761@1|root,COG0761@2|Bacteria,1MU7G@1224|Proteobacteria,1RMN8@1236|Gammaproteobacteria,1YVSX@136845|Pseudomonas putida group	1236|Gammaproteobacteria	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0042380,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046490,GO:0048037,GO:0051536,GO:0051538,GO:0051540,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	iECIAI1_1343.ECIAI1_0030,iECW_1372.ECW_m0028,iEKO11_1354.EKO11_3884,iEcHS_1320.EcHS_A0031,iEcolC_1368.EcolC_3626,iPC815.YPO0477,iSFV_1184.SFV_0023,iSF_1195.SF0026,iSFxv_1172.SFxv_0027,iS_1188.S0028,iWFL_1372.ECW_m0028,iYL1228.KPN_00024	LYTB
CMS1_k127_1603977_17	1304284.L21TH_1682	3.131e-08	63.0	COG0695@1|root,COG0695@2|Bacteria,1VI6J@1239|Firmicutes,24QNT@186801|Clostridia,36N2I@31979|Clostridiaceae	186801|Clostridia	O	glutaredoxin-like protein, YruB-family	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
CMS1_k127_1603977_16	1122134.KB893651_gene2425	2.953e-09	64.0	2DR2Y@1|root,339YA@2|Bacteria,1NHB7@1224|Proteobacteria,1SH0X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4124)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124
CMS1_k127_1655728_7	498211.CJA_3346	4.14e-153	491.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,1RNHY@1236|Gammaproteobacteria,1FGQ0@10|Cellvibrio	1236|Gammaproteobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	GO:0006457,GO:0008150,GO:0009987	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
CMS1_k127_1655728_1	243233.MCA1856	3.36e-322	995.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,1RMDD@1236|Gammaproteobacteria,1XDUN@135618|Methylococcales	135618|Methylococcales	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
CMS1_k127_1655728_32	713586.KB900536_gene3030	1.115e-43	168.0	COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,1S5W5@1236|Gammaproteobacteria,1WY2F@135613|Chromatiales	135613|Chromatiales	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
CMS1_k127_1655728_12	105559.Nwat_0275	4.05e-121	398.0	COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,1RR2F@1236|Gammaproteobacteria,1WXB7@135613|Chromatiales	135613|Chromatiales	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
CMS1_k127_1655728_23	472759.Nhal_0879	7.521e-78	273.0	COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,1RP84@1236|Gammaproteobacteria,1WXJR@135613|Chromatiales	135613|Chromatiales	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
CMS1_k127_1655728_10	519989.ECTPHS_06952	4.213e-139	466.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,1RNPZ@1236|Gammaproteobacteria,1WW15@135613|Chromatiales	135613|Chromatiales	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
CMS1_k127_1655728_28	1415779.JOMH01000001_gene2740	1.651e-55	198.0	COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,1S4H7@1236|Gammaproteobacteria,1X6F1@135614|Xanthomonadales	135614|Xanthomonadales	K	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
CMS1_k127_1655728_37	754477.Q7C_1015	1.683e-34	143.0	COG2913@1|root,COG2913@2|Bacteria,1N6YW@1224|Proteobacteria,1SCTT@1236|Gammaproteobacteria,4619W@72273|Thiotrichales	72273|Thiotrichales	J	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamE	-	-	ko:K06186	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	SmpA_OmlA
CMS1_k127_1655728_38	1286093.C266_00580	4.881e-25	108.0	COG2914@1|root,COG2914@2|Bacteria,1MZCH@1224|Proteobacteria,2VVNX@28216|Betaproteobacteria,1K8F3@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Belongs to the UPF0125 (RnfH) family	rnfH	-	-	ko:K09801	-	-	-	-	ko00000	-	-	-	Ub-RnfH
CMS1_k127_1655728_35	870187.Thini_4089	1.377e-41	157.0	COG2867@1|root,COG2867@2|Bacteria,1RGUH@1224|Proteobacteria,1S61C@1236|Gammaproteobacteria,4611H@72273|Thiotrichales	72273|Thiotrichales	I	Polyketide cyclase dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
CMS1_k127_1655728_24	396588.Tgr7_0962	1.588e-67	233.0	COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,1S3PT@1236|Gammaproteobacteria,1WX50@135613|Chromatiales	135613|Chromatiales	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
CMS1_k127_1655728_13	1123393.KB891316_gene1621	6.49e-121	402.0	COG1538@1|root,COG1538@2|Bacteria,1NW1T@1224|Proteobacteria,2VQKM@28216|Betaproteobacteria,1KSPY@119069|Hydrogenophilales	119069|Hydrogenophilales	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
CMS1_k127_1655728_8	205922.Pfl01_2395	5.112e-144	470.0	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,1RPBZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	cusB	GO:0000041,GO:0003674,GO:0005215,GO:0005375,GO:0005488,GO:0005507,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0006873,GO:0006875,GO:0006878,GO:0006950,GO:0008150,GO:0008324,GO:0009636,GO:0009987,GO:0010035,GO:0010038,GO:0010272,GO:0010273,GO:0015075,GO:0015318,GO:0015679,GO:0019725,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030288,GO:0030313,GO:0031975,GO:0034220,GO:0035434,GO:0042221,GO:0042592,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0046688,GO:0046872,GO:0046873,GO:0046914,GO:0046915,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051234,GO:0055065,GO:0055070,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0060003,GO:0061687,GO:0065007,GO:0065008,GO:0097501,GO:0098655,GO:0098660,GO:0098662,GO:0098754,GO:0098771,GO:1990169	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	iECSF_1327.ECSF_0504	CusF_Ec,HlyD_D23,HlyD_D4
CMS1_k127_1655728_0	1149133.ppKF707_4661	0.0	1553.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1SP6I@1236|Gammaproteobacteria,1YE67@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	P	AcrB/AcrD/AcrF family	cusA	GO:0000041,GO:0003674,GO:0005215,GO:0005375,GO:0005488,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0006873,GO:0006875,GO:0006878,GO:0006950,GO:0008150,GO:0008324,GO:0009636,GO:0009987,GO:0010035,GO:0010038,GO:0010272,GO:0010273,GO:0015075,GO:0015080,GO:0015318,GO:0015673,GO:0015679,GO:0016020,GO:0016021,GO:0019725,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0031224,GO:0034220,GO:0035434,GO:0042221,GO:0042592,GO:0043167,GO:0043169,GO:0044425,GO:0044464,GO:0046688,GO:0046872,GO:0046873,GO:0046914,GO:0046915,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051234,GO:0055065,GO:0055070,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0060003,GO:0061687,GO:0065007,GO:0065008,GO:0071944,GO:0097501,GO:0098655,GO:0098660,GO:0098662,GO:0098754,GO:0098771,GO:1902601,GO:1990169	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	iB21_1397.B21_00525,iECBD_1354.ECBD_3087,iECB_1328.ECB_00536,iECD_1391.ECD_00536	ACR_tran
CMS1_k127_1655728_22	1163617.SCD_n02058	7.903e-86	297.0	COG2199@1|root,COG3159@1|root,COG3159@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2WEJC@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	DUF484,GGDEF
CMS1_k127_1655728_6	396588.Tgr7_2714	2.097e-183	599.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,1RQEX@1236|Gammaproteobacteria,1WWF6@135613|Chromatiales	135613|Chromatiales	M	Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA,OstA_C
CMS1_k127_1655728_11	472759.Nhal_2085	5.928e-132	434.0	COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,1RMWU@1236|Gammaproteobacteria,1WVWN@135613|Chromatiales	135613|Chromatiales	M	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,SurA_N
CMS1_k127_1655728_14	1122603.ATVI01000009_gene2590	6.858e-118	389.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,1RNZV@1236|Gammaproteobacteria,1X2ZP@135614|Xanthomonadales	135614|Xanthomonadales	H	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)	pdxA	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
CMS1_k127_1655728_21	396588.Tgr7_2718	1.024e-86	293.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,1RMHW@1236|Gammaproteobacteria,1WWC4@135613|Chromatiales	135613|Chromatiales	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
CMS1_k127_1655728_19	395493.BegalDRAFT_3002	5.21e-93	313.0	COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,1RPB7@1236|Gammaproteobacteria,460E1@72273|Thiotrichales	72273|Thiotrichales	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
CMS1_k127_1655728_20	391615.ABSJ01000026_gene110	3.158e-91	311.0	COG0607@1|root,COG0664@1|root,COG0607@2|Bacteria,COG0664@2|Bacteria,1R9Q1@1224|Proteobacteria,1RSKD@1236|Gammaproteobacteria,1J6A4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	PT	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,cNMP_binding
CMS1_k127_1655728_5	697282.Mettu_3259	6.072e-186	591.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RNKF@1236|Gammaproteobacteria,1XEUM@135618|Methylococcales	135618|Methylococcales	P	PFAM Ammonium Transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
CMS1_k127_1655728_27	335284.Pcryo_2346	7.086e-56	197.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,1S67I@1236|Gammaproteobacteria,3NNHG@468|Moraxellaceae	1236|Gammaproteobacteria	K	Belongs to the P(II) protein family	glnK	-	-	ko:K04752	-	-	-	-	ko00000	-	-	-	P-II
CMS1_k127_1655728_4	765911.Thivi_3470	9.889e-200	633.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RNKF@1236|Gammaproteobacteria,1WWT4@135613|Chromatiales	135613|Chromatiales	U	Ammonium transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
CMS1_k127_1655728_29	395493.BegalDRAFT_2652	5.288e-54	191.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,1S67I@1236|Gammaproteobacteria,460Q2@72273|Thiotrichales	72273|Thiotrichales	K	nitrogen regulatory protein P-II	-	-	-	ko:K04751,ko:K04752	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
CMS1_k127_1655728_34	1415778.JQMM01000001_gene148	4.056e-43	167.0	2C5U9@1|root,2Z9NJ@2|Bacteria,1R8VZ@1224|Proteobacteria,1RWKX@1236|Gammaproteobacteria,1JBXA@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Bacterial protein of unknown function (Gcw_chp)	-	-	-	-	-	-	-	-	-	-	-	-	Gcw_chp
CMS1_k127_1655728_40	1026882.MAMP_00444	1.077e-13	73.0	COG2960@1|root,COG2960@2|Bacteria,1N7AH@1224|Proteobacteria,1SCH1@1236|Gammaproteobacteria,461BQ@72273|Thiotrichales	72273|Thiotrichales	S	Membrane fusogenic activity	-	-	-	ko:K09806	-	-	-	-	ko00000	-	-	-	BMFP
CMS1_k127_1655728_3	768671.ThimaDRAFT_3222	5.942e-209	660.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,1RMB9@1236|Gammaproteobacteria,1WWMF@135613|Chromatiales	135613|Chromatiales	O	PFAM Magnesium chelatase, ChlI subunit	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
CMS1_k127_1655728_31	396588.Tgr7_2722	1.83e-50	181.0	COG2967@1|root,COG2967@2|Bacteria,1MZ2Z@1224|Proteobacteria,1S8SE@1236|Gammaproteobacteria,1WYSF@135613|Chromatiales	135613|Chromatiales	P	PFAM ApaG domain protein	apaG	-	-	ko:K06195	-	-	-	-	ko00000	-	-	-	DUF525
CMS1_k127_1655728_18	572477.Alvin_2150	9.998e-98	327.0	COG0639@1|root,COG0639@2|Bacteria,1MV10@1224|Proteobacteria,1RPUJ@1236|Gammaproteobacteria,1WVWS@135613|Chromatiales	135613|Chromatiales	T	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP	apaH	-	3.6.1.41	ko:K01525	ko00230,map00230	-	R00125	RC00002	ko00000,ko00001,ko01000	-	-	-	Metallophos
CMS1_k127_1655728_17	349521.HCH_02826	7.021e-103	339.0	COG0412@1|root,COG0412@2|Bacteria,1NKIB@1224|Proteobacteria,1RRYE@1236|Gammaproteobacteria,1XJAB@135619|Oceanospirillales	135619|Oceanospirillales	Q	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DLH
CMS1_k127_1655728_25	1038859.AXAU01000004_gene4599	1.998e-62	228.0	COG4313@1|root,COG4313@2|Bacteria,1N1DR@1224|Proteobacteria,2UV3I@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Protein involved in meta-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1655728_26	265072.Mfla_1186	6.627e-58	206.0	COG1225@1|root,COG1225@2|Bacteria,1RH4P@1224|Proteobacteria,2VT1P@28216|Betaproteobacteria,2KMST@206350|Nitrosomonadales	206350|Nitrosomonadales	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
CMS1_k127_1655728_2	76114.ebA1848	7.89e-244	771.0	COG0577@1|root,COG1136@1|root,COG0577@2|Bacteria,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2VHZ2@28216|Betaproteobacteria,2KV7V@206389|Rhodocyclales	206389|Rhodocyclales	V	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	macB	-	-	ko:K05685	ko02010,map02010	M00709	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.122.1,3.A.1.122.12	-	-	ABC_tran,FtsX,MacB_PCD
CMS1_k127_1655728_15	1380391.JIAS01000012_gene4252	1.38e-112	376.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,2TV4H@28211|Alphaproteobacteria,2JR0E@204441|Rhodospirillales	204441|Rhodospirillales	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	HlyD_D23
CMS1_k127_1655728_30	1026882.MAMP_00873	7.114e-52	188.0	COG0262@1|root,COG0262@2|Bacteria,1RH0P@1224|Proteobacteria,1S5VH@1236|Gammaproteobacteria,460W3@72273|Thiotrichales	72273|Thiotrichales	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	-	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	DHFR_1
CMS1_k127_1655728_9	870187.Thini_0749	2.534e-141	452.0	COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,1RPYV@1236|Gammaproteobacteria,45ZPG@72273|Thiotrichales	72273|Thiotrichales	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
CMS1_k127_1655728_16	472759.Nhal_3905	1.845e-106	351.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,1RMVK@1236|Gammaproteobacteria,1WW3W@135613|Chromatiales	135613|Chromatiales	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
CMS1_k127_1655728_33	754476.Q7A_1976	1.771e-43	167.0	28KE4@1|root,2ZA0D@2|Bacteria,1MXZT@1224|Proteobacteria,1RYV4@1236|Gammaproteobacteria,4618K@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1655728_36	1283300.ATXB01000001_gene124	4.432e-35	136.0	COG0672@1|root,COG0672@2|Bacteria,1N48M@1224|Proteobacteria,1S7GF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	)-iron permease	-	-	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	FTR1
CMS1_k127_1655745_1	1454004.AW11_00300	8.583e-120	391.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria	28216|Betaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.9	ko:K01539	ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978	-	-	-	ko00000,ko00001,ko01000,ko04147	3.A.3.1	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
CMS1_k127_1655745_0	768671.ThimaDRAFT_3804	9.119e-174	558.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,1RM9U@1236|Gammaproteobacteria,1WXMK@135613|Chromatiales	135613|Chromatiales	S	Polyphosphate AMP phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
CMS1_k127_1655745_3	292415.Tbd_2732	5.799e-66	235.0	COG3850@1|root,COG3850@2|Bacteria,1N23T@1224|Proteobacteria,2VQFG@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Type IV pili methyl-accepting chemotaxis transducer N-term	-	-	-	-	-	-	-	-	-	-	-	-	PilJ
CMS1_k127_1655745_2	1500301.JQMF01000010_gene2266	1.402e-95	325.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,2TVGG@28211|Alphaproteobacteria,4B84Q@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
CMS1_k127_1677635_0	754476.Q7A_3035	3.192e-172	549.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,1RMMQ@1236|Gammaproteobacteria,45ZNI@72273|Thiotrichales	72273|Thiotrichales	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
CMS1_k127_1677635_13	1049564.TevJSym_ai00820	2.289e-41	162.0	COG3161@1|root,COG3161@2|Bacteria,1N8BF@1224|Proteobacteria,1SDX2@1236|Gammaproteobacteria,1J6IV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway	ubiC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008813,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	4.1.3.40	ko:K03181	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R01302	RC00491,RC02148	ko00000,ko00001,ko00002,ko01000	-	-	iZ_1308.Z5638	Chor_lyase
CMS1_k127_1677635_5	349124.Hhal_0965	6.106e-95	334.0	COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,1RMZ1@1236|Gammaproteobacteria,1WWA7@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
CMS1_k127_1677635_18	1049564.TevJSym_ai00990	1.301e-09	68.0	2E02Y@1|root,314WY@2|Bacteria,1PUUX@1224|Proteobacteria,1SWX3@1236|Gammaproteobacteria,1J7A5@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1677635_12	323261.Noc_0189	1.945e-54	199.0	COG1521@1|root,COG1521@2|Bacteria,1MUYA@1224|Proteobacteria,1S99V@1236|Gammaproteobacteria,1WWDC@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
CMS1_k127_1677635_10	686340.Metal_0899	2.411e-76	267.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1MWCC@1224|Proteobacteria,1RNGC@1236|Gammaproteobacteria,1XDR3@135618|Methylococcales	135618|Methylococcales	K	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
CMS1_k127_1677635_11	472759.Nhal_0826	2.323e-63	239.0	COG1716@1|root,COG2304@1|root,COG1716@2|Bacteria,COG2304@2|Bacteria,1MVJ2@1224|Proteobacteria,1SITG@1236|Gammaproteobacteria,1WZTK@135613|Chromatiales	135613|Chromatiales	T	von Willebrand factor, type A	-	-	-	-	-	-	-	-	-	-	-	-	VWA
CMS1_k127_1677635_6	518766.Rmar_0188	1.866e-88	302.0	COG2897@1|root,COG2897@2|Bacteria,4NF85@976|Bacteroidetes	976|Bacteroidetes	P	sulfurtransferase	sseA	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
CMS1_k127_1677635_7	395493.BegalDRAFT_0614	2.464e-88	303.0	COG4324@1|root,COG4324@2|Bacteria,1N0FE@1224|Proteobacteria,1S0UK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Aminopep
CMS1_k127_1677635_15	330214.NIDE3217	4.781e-29	125.0	COG1678@1|root,COG1678@2|Bacteria	2|Bacteria	K	ribonucleoside-diphosphate reductase activity	yqgE	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
CMS1_k127_1677635_2	1123399.AQVE01000005_gene878	3.478e-143	461.0	COG0473@1|root,COG0473@2|Bacteria,1QU2H@1224|Proteobacteria,1T1N6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	CE	Isocitrate isopropylmalate dehydrogenase	-	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
CMS1_k127_1677635_3	211165.AJLN01000083_gene1483	1.659e-115	376.0	COG0175@1|root,COG0175@2|Bacteria,1G1RY@1117|Cyanobacteria,1JJ24@1189|Stigonemataceae	1117|Cyanobacteria	EH	Phosphoadenosine phosphosulfate reductase family	cysH	GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0044424,GO:0044464,GO:0055114	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
CMS1_k127_1677635_14	1122194.AUHU01000002_gene2752	1.042e-37	144.0	2EAR8@1|root,334TE@2|Bacteria,1NDFF@1224|Proteobacteria,1SCX2@1236|Gammaproteobacteria,468HF@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1677635_1	1123279.ATUS01000001_gene627	1.559e-147	473.0	COG0583@1|root,COG0583@2|Bacteria,1MU8N@1224|Proteobacteria,1RN7T@1236|Gammaproteobacteria,1J4E3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	Transcriptional regulator	cysB	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0097159,GO:1901363	-	ko:K13634	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
CMS1_k127_1677635_9	395494.Galf_1983	1.738e-85	290.0	COG0730@1|root,COG0730@2|Bacteria,1MWX2@1224|Proteobacteria,2VMUD@28216|Betaproteobacteria,44VN0@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
CMS1_k127_1677635_19	156889.Mmc1_1457	1.343e-08	60.0	COG2841@1|root,COG2841@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF465)	VPA0402	-	-	ko:K09794	-	-	-	-	ko00000	-	-	-	DUF465
CMS1_k127_1677635_8	1122604.JONR01000015_gene201	9.078e-86	296.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1S0BJ@1236|Gammaproteobacteria,1XCIH@135614|Xanthomonadales	135614|Xanthomonadales	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
CMS1_k127_1677635_16	56110.Oscil6304_5722	1.15e-27	115.0	COG2331@1|root,COG2331@2|Bacteria	2|Bacteria	P	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
CMS1_k127_1677635_4	1282876.BAOK01000002_gene590	1.101e-109	360.0	COG0491@1|root,COG0491@2|Bacteria,1MU8Q@1224|Proteobacteria,2TSVS@28211|Alphaproteobacteria,4BPZF@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	gloB	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	HAGH_C,Lactamase_B
CMS1_k127_1677635_17	402881.Plav_1318	2.092e-13	72.0	COG4122@1|root,COG4122@2|Bacteria,1QXHD@1224|Proteobacteria,2VF7P@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Macrocin-O-methyltransferase (TylF)	-	-	-	-	-	-	-	-	-	-	-	-	TylF
CMS1_k127_1757212_29	1121943.KB899995_gene769	1.318e-42	158.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,1RN5D@1236|Gammaproteobacteria,1XH89@135619|Oceanospirillales	135619|Oceanospirillales	G	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	PQQ
CMS1_k127_1757212_34	472759.Nhal_3868	6.239e-25	109.0	COG3794@1|root,COG3794@2|Bacteria,1MZWU@1224|Proteobacteria,1SDMY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	PFAM Copper binding proteins, plastocyanin azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
CMS1_k127_1757212_23	395493.BegalDRAFT_0064	4.12e-65	232.0	COG0834@1|root,COG0834@2|Bacteria,1MWWZ@1224|Proteobacteria,1S2ZV@1236|Gammaproteobacteria,462HI@72273|Thiotrichales	72273|Thiotrichales	ET	PFAM Bacterial extracellular solute-binding proteins, family 3	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_3
CMS1_k127_1757212_31	543728.Vapar_3043	5.155e-38	153.0	2C1VZ@1|root,32R98@2|Bacteria,1RJ8X@1224|Proteobacteria,2VRVA@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1757212_1	187272.Mlg_2513	0.0	1197.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,1T1JA@1236|Gammaproteobacteria,1X2PM@135613|Chromatiales	135613|Chromatiales	C	TIGRFAM formate dehydrogenase, alpha subunit	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4_9,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CMS1_k127_1757212_3	472759.Nhal_2430	1.489e-263	821.0	COG1894@1|root,COG1905@1|root,COG1894@2|Bacteria,COG1905@2|Bacteria,1MV8F@1224|Proteobacteria,1RMUD@1236|Gammaproteobacteria,1X03E@135613|Chromatiales	135613|Chromatiales	C	Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit	-	-	1.17.1.9	ko:K00122	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
CMS1_k127_1757212_26	1000565.METUNv1_01443	1.534e-62	226.0	COG2218@1|root,COG2218@2|Bacteria,1MUUQ@1224|Proteobacteria,2VMB1@28216|Betaproteobacteria,2KWSN@206389|Rhodocyclales	206389|Rhodocyclales	C	GXGXG motif	-	-	1.2.7.12	ko:K00202	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R03015,R08060,R11743	RC00197,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	GXGXG
CMS1_k127_1757212_11	472759.Nhal_0013	1.786e-126	411.0	COG2037@1|root,COG2037@2|Bacteria,1MVSD@1224|Proteobacteria,1S0G2@1236|Gammaproteobacteria,1X08I@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)	ffsA	-	2.3.1.101	ko:K00672	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R03390	RC00197,RC00870,RC02881	ko00000,ko00001,ko00002,ko01000	-	-	-	FTR,FTR_C
CMS1_k127_1757212_2	472759.Nhal_0014	1.008e-268	836.0	COG1229@1|root,COG1229@2|Bacteria,1NX13@1224|Proteobacteria,1RZ5G@1236|Gammaproteobacteria,1X07F@135613|Chromatiales	135613|Chromatiales	C	TIGRFAM Formylmethanofuran dehydrogenase, subunit A	-	-	1.2.7.12	ko:K00200	ko00680,ko01100,ko01120,ko01130,ko01200,map00680,map01100,map01120,map01130,map01200	M00567	R03015,R08060	RC00197,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_3
CMS1_k127_1757212_14	472759.Nhal_0015	2.395e-101	345.0	COG1029@1|root,COG1029@2|Bacteria,1R64R@1224|Proteobacteria,1RNM2@1236|Gammaproteobacteria,1X05Q@135613|Chromatiales	135613|Chromatiales	C	TIGRFAM formylmethanofuran dehydrogenase subunit B	-	-	1.2.7.12	ko:K00201	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R03015,R08060	RC00197,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	-
CMS1_k127_1757212_8	502025.Hoch_6598	5.104e-172	550.0	COG0493@1|root,COG0493@2|Bacteria,1P58U@1224|Proteobacteria,4392A@68525|delta/epsilon subdivisions,2X47Z@28221|Deltaproteobacteria,2YYG2@29|Myxococcales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	Pyr_redox_2
CMS1_k127_1757212_30	391625.PPSIR1_21764	8.309e-39	147.0	COG1146@1|root,COG1146@2|Bacteria,1RH5I@1224|Proteobacteria,43C2Q@68525|delta/epsilon subdivisions,2WSJ0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions	-	-	-	ko:K05524	-	-	-	-	ko00000	-	-	-	DUF3470,Fer4
CMS1_k127_1757212_21	1380390.JIAT01000010_gene4328	2.066e-67	238.0	COG2218@1|root,COG2218@2|Bacteria	2|Bacteria	C	formylmethanofuran dehydrogenase activity	fhcC	GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0044237,GO:0044281	1.2.7.12	ko:K00202	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R03015,R08060,R11743	RC00197,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	GXGXG
CMS1_k127_1757212_13	1380390.JIAT01000010_gene4327	9.003e-116	379.0	COG2037@1|root,COG2037@2|Bacteria	2|Bacteria	H	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)	ffsA	GO:0003674,GO:0003824,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0015947,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0030270,GO:0043446,GO:0044237,GO:0044281,GO:0071704	2.3.1.101	ko:K00672	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R03390	RC00197,RC00870,RC02881	ko00000,ko00001,ko00002,ko01000	-	-	-	FTR,FTR_C
CMS1_k127_1757212_6	1380390.JIAT01000010_gene4326	1.199e-204	650.0	COG1229@1|root,COG1229@2|Bacteria	2|Bacteria	C	Formylmethanofuran dehydrogenase subunit A	fhcA	GO:0003674,GO:0003824,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0044237,GO:0044281	1.2.7.12	ko:K00200	ko00680,ko01100,ko01120,ko01130,ko01200,map00680,map01100,map01120,map01130,map01200	M00567	R03015,R08060	RC00197,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_3
CMS1_k127_1757212_10	592015.HMPREF1705_02175	5.182e-137	451.0	COG1029@1|root,COG1029@2|Bacteria,3TBWP@508458|Synergistetes	508458|Synergistetes	C	Molybdopterin oxidoreductase	-	-	1.2.7.12	ko:K00201	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R03015,R08060	RC00197,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Molybdopterin
CMS1_k127_1757212_35	523845.AQXV01000021_gene1298	2.756e-11	68.0	COG1153@1|root,arCOG02674@2157|Archaea,2XXYM@28890|Euryarchaeota,23QYY@183939|Methanococci	183939|Methanococci	C	PFAM molydopterin dinucleotide-binding region	-	-	1.2.7.12	ko:K00203	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R03015,R08060,R11743	RC00197,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Molydop_binding
CMS1_k127_1757212_17	395493.BegalDRAFT_1633	2.246e-98	332.0	COG1907@1|root,COG1907@2|Bacteria,1MWHM@1224|Proteobacteria,1RQC1@1236|Gammaproteobacteria,4629S@72273|Thiotrichales	72273|Thiotrichales	S	PFAM GHMP kinases C terminal	-	-	-	-	-	-	-	-	-	-	-	-	GHMP_kinases_C,GHMP_kinases_N
CMS1_k127_1757212_16	1000565.METUNv1_01449	1.623e-99	332.0	COG0373@1|root,COG0373@2|Bacteria,1MXX5@1224|Proteobacteria,2VK09@28216|Betaproteobacteria,2KZYB@206389|Rhodocyclales	28216|Betaproteobacteria	H	Methylene-tetrahydromethanopterin dehydrogenase, N-terminal	-	-	-	ko:K10714	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	-	R08059	RC00202	ko00000,ko00001,ko01000	-	-	-	Mpt_N
CMS1_k127_1757212_20	395493.BegalDRAFT_1140	7.681e-69	248.0	COG2232@1|root,COG2232@2|Bacteria,1R6Y7@1224|Proteobacteria,1S781@1236|Gammaproteobacteria,462YR@72273|Thiotrichales	72273|Thiotrichales	S	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_3
CMS1_k127_1757212_12	1123393.KB891326_gene161	3.234e-124	406.0	COG3252@1|root,COG3252@2|Bacteria,1MUP6@1224|Proteobacteria,2VMCD@28216|Betaproteobacteria,1KSX8@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Cyclohydrolase (MCH)	-	-	-	-	-	-	-	-	-	-	-	-	MCH
CMS1_k127_1757212_15	1123393.KB891326_gene160	7.638e-100	335.0	COG0189@1|root,COG0189@2|Bacteria,1MX62@1224|Proteobacteria,2VJZS@28216|Betaproteobacteria,1KSNA@119069|Hydrogenophilales	119069|Hydrogenophilales	HJ	RimK-like ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	RimK
CMS1_k127_1757212_22	1101195.Meth11DRAFT_1413	1.739e-65	233.0	COG1767@1|root,COG1767@2|Bacteria,1RAWI@1224|Proteobacteria,2VQ7E@28216|Betaproteobacteria,2KKD8@206350|Nitrosomonadales	206350|Nitrosomonadales	H	PFAM triphosphoribosyl-dephospho-CoA protein	-	-	2.4.2.52	ko:K05966	ko02020,map02020	-	R09675	RC00049,RC00063	ko00000,ko00001,ko01000	-	-	-	CitG
CMS1_k127_1757212_18	765913.ThidrDRAFT_0568	2.877e-84	283.0	COG1795@1|root,COG1795@2|Bacteria,1NDRY@1224|Proteobacteria,1S3C1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PFAM Formaldehyde-activating enzyme	-	-	4.2.1.147	ko:K10713	ko00680,ko01120,ko01200,map00680,map01120,map01200	-	R08058	RC01583,RC01795	ko00000,ko00001,ko01000	-	-	-	Fae
CMS1_k127_1757212_28	582744.Msip34_1494	2.459e-54	199.0	COG1411@1|root,COG1411@2|Bacteria,1RHWE@1224|Proteobacteria,2VTJW@28216|Betaproteobacteria,2KMS0@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Belongs to the HisA HisF family	-	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
CMS1_k127_1757212_27	582744.Msip34_1493	3.669e-58	215.0	COG1821@1|root,COG1821@2|Bacteria,1RBY6@1224|Proteobacteria,2VQ4F@28216|Betaproteobacteria,2KMTW@206350|Nitrosomonadales	206350|Nitrosomonadales	S	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_3
CMS1_k127_1757212_19	395493.BegalDRAFT_2406	5.322e-81	282.0	COG1548@1|root,COG1548@2|Bacteria,1RAMA@1224|Proteobacteria,1S26G@1236|Gammaproteobacteria,461YG@72273|Thiotrichales	72273|Thiotrichales	GK	H4MPT-linked C1 transfer pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	Hydantoinase_A
CMS1_k127_1757212_9	686340.Metal_2828	3.258e-164	530.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,1XDNC@135618|Methylococcales	135618|Methylococcales	EH	synthase component I	pabB	-	2.6.1.85	ko:K01665	ko00790,map00790	-	R01716	RC00010,RC01418	ko00000,ko00001,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
CMS1_k127_1757212_33	472759.Nhal_3884	1.079e-32	134.0	COG2054@1|root,COG2054@2|Bacteria,1MZY4@1224|Proteobacteria,1S9PH@1236|Gammaproteobacteria,1X0ZK@135613|Chromatiales	135613|Chromatiales	H	Amino acid kinase family	-	-	-	-	-	-	-	-	-	-	-	-	AA_kinase
CMS1_k127_1757212_7	395493.BegalDRAFT_0784	3.662e-187	600.0	COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,1SMN1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	PhaC_N
CMS1_k127_1757212_32	1123073.KB899243_gene495	1.014e-33	136.0	COG3832@1|root,COG3832@2|Bacteria,1RD9A@1224|Proteobacteria,1S95U@1236|Gammaproteobacteria,1XC4A@135614|Xanthomonadales	135614|Xanthomonadales	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
CMS1_k127_1757212_5	713587.THITH_04535	9.738e-207	649.0	COG0208@1|root,COG0208@2|Bacteria,1MWUS@1224|Proteobacteria,1RMJC@1236|Gammaproteobacteria,1WWJN@135613|Chromatiales	135613|Chromatiales	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	-	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
CMS1_k127_1757212_0	396588.Tgr7_2615	0.0	1469.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,1RMPV@1236|Gammaproteobacteria,1WW6H@135613|Chromatiales	135613|Chromatiales	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,LAGLIDADG_3,Ribonuc_red_lgC,Ribonuc_red_lgN
CMS1_k127_1757212_4	396588.Tgr7_1907	1.184e-216	688.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,1RNGV@1236|Gammaproteobacteria,1WWEF@135613|Chromatiales	135613|Chromatiales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
CMS1_k127_1757212_24	631362.Thi970DRAFT_04589	4.601e-64	224.0	COG0558@1|root,COG0558@2|Bacteria,1RCZ7@1224|Proteobacteria,1S465@1236|Gammaproteobacteria,1WXKW@135613|Chromatiales	135613|Chromatiales	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
CMS1_k127_1757212_36	1122164.JHWF01000022_gene1710	1.619e-09	63.0	2APXH@1|root,31F27@2|Bacteria,1QCFC@1224|Proteobacteria,1T85P@1236|Gammaproteobacteria,1JGAF@118969|Legionellales	118969|Legionellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1757212_25	267608.RSc0968	2.451e-63	223.0	COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,2VHG5@28216|Betaproteobacteria,1KFH3@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_3,Phage_int_SAM_3,Phage_integrase
CMS1_k127_1806699_4	472759.Nhal_2908	1.868e-65	236.0	COG0392@1|root,COG0392@2|Bacteria,1RCBH@1224|Proteobacteria,1S366@1236|Gammaproteobacteria,1X1IF@135613|Chromatiales	135613|Chromatiales	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
CMS1_k127_1806699_5	572477.Alvin_1396	2.819e-65	228.0	COG2862@1|root,COG2862@2|Bacteria,1RANN@1224|Proteobacteria,1S2DE@1236|Gammaproteobacteria,1WY01@135613|Chromatiales	135613|Chromatiales	S	TIGRFAM TIGR00645 family protein	-	-	-	-	-	-	-	-	-	-	-	-	UPF0114
CMS1_k127_1806699_0	658612.MD26_06650	3.309e-136	444.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,1RN6I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	yggW	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
CMS1_k127_1806699_3	926560.KE387023_gene2306	4.573e-94	323.0	COG0520@1|root,COG0520@2|Bacteria	2|Bacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	cefD	-	5.1.1.17	ko:K04127,ko:K11325,ko:K21174	ko00311,ko01059,ko01100,ko01130,map00311,map01059,map01100,map01130	M00673,M00825	R04147	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
CMS1_k127_1806699_1	1287116.X734_07990	9.721e-113	392.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Collar,HemolysinCabind,Peptidase_M10_C
CMS1_k127_1806699_6	686340.Metal_3822	4.779e-08	66.0	COG2304@1|root,COG2931@1|root,COG2304@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1S67V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta
CMS1_k127_1806699_2	290317.Cpha266_1840	4.294e-98	340.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria	2|Bacteria	O	protein N-acetylglucosaminyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,TPR_1,TPR_11,TPR_16,TPR_2,TPR_4,TPR_8
CMS1_k127_1810762_1	395494.Galf_0655	1.097e-126	411.0	COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,2VI3K@28216|Betaproteobacteria,44W8Q@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase,OmpA
CMS1_k127_1810762_0	472759.Nhal_0506	2.428e-208	655.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,1RMVY@1236|Gammaproteobacteria,1WWG7@135613|Chromatiales	135613|Chromatiales	G	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
CMS1_k127_1810762_2	472759.Nhal_3508	5.669e-119	399.0	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,1RP5S@1236|Gammaproteobacteria,1WWCN@135613|Chromatiales	135613|Chromatiales	S	Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TPR_19
CMS1_k127_1810762_5	1049564.TevJSym_aw00360	1.591e-29	126.0	COG5501@1|root,COG5501@2|Bacteria,1RH4J@1224|Proteobacteria,1S2ZH@1236|Gammaproteobacteria,1J8B0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Sulfur oxidation protein SoxY	soxY	-	-	ko:K17226	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxY
CMS1_k127_1810762_6	288000.BBta_0695	4.112e-27	118.0	COG5501@1|root,COG5501@2|Bacteria,1N097@1224|Proteobacteria,2U9JC@28211|Alphaproteobacteria,3JZE0@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Sulphur oxidation protein SoxZ	MA20_22825	-	-	ko:K17227	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxZ
CMS1_k127_1810762_3	502025.Hoch_0991	1.766e-98	331.0	COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria,4313Z@68525|delta/epsilon subdivisions,2WX2K@28221|Deltaproteobacteria,2Z2QP@29|Myxococcales	28221|Deltaproteobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
CMS1_k127_1810762_4	267608.RSp0090	1.255e-44	171.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,2VIHD@28216|Betaproteobacteria,1K1BK@119060|Burkholderiaceae	28216|Betaproteobacteria	D	Tyrosine recombinase XerD	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
CMS1_k127_1835984_23	519989.ECTPHS_13183	8.089e-24	104.0	COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,1RMU3@1236|Gammaproteobacteria,1WWB2@135613|Chromatiales	135613|Chromatiales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
CMS1_k127_1835984_3	765914.ThisiDRAFT_1665	1.939e-101	333.0	COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,1RQ38@1236|Gammaproteobacteria,1WW34@135613|Chromatiales	135613|Chromatiales	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
CMS1_k127_1835984_9	455436.DS989811_gene1928	8.395e-67	229.0	COG0100@1|root,COG0100@2|Bacteria,1RD0A@1224|Proteobacteria,1S3Q2@1236|Gammaproteobacteria,466ID@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
CMS1_k127_1835984_14	396588.Tgr7_2302	8.455e-51	182.0	COG0099@1|root,COG0099@2|Bacteria,1RD1G@1224|Proteobacteria,1S3NX@1236|Gammaproteobacteria,1WYHF@135613|Chromatiales	135613|Chromatiales	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
CMS1_k127_1835984_27	742821.HMPREF9464_01729	1.065e-11	71.0	COG0257@1|root,COG0257@2|Bacteria,1NGEI@1224|Proteobacteria,2VXPQ@28216|Betaproteobacteria,4PREW@995019|Sutterellaceae	28216|Betaproteobacteria	J	Ribosomal protein L36	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
CMS1_k127_1835984_0	395493.BegalDRAFT_2604	1.555e-213	670.0	COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,1RNJV@1236|Gammaproteobacteria,45ZXN@72273|Thiotrichales	72273|Thiotrichales	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
CMS1_k127_1835984_12	998674.ATTE01000001_gene4300	1.878e-53	192.0	COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,1S3P6@1236|Gammaproteobacteria,460T4@72273|Thiotrichales	72273|Thiotrichales	J	binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
CMS1_k127_1835984_25	1260251.SPISAL_07385	8.594e-19	88.0	COG1841@1|root,COG1841@2|Bacteria,1N6ZE@1224|Proteobacteria,1SC8N@1236|Gammaproteobacteria,1WZ8N@135613|Chromatiales	135613|Chromatiales	J	Ribosomal protein L30	rpmD	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
CMS1_k127_1835984_8	519989.ECTPHS_13143	2.094e-68	235.0	COG0098@1|root,COG0098@2|Bacteria,1MUS4@1224|Proteobacteria,1RNEV@1236|Gammaproteobacteria,1WX2D@135613|Chromatiales	135613|Chromatiales	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
CMS1_k127_1835984_16	395493.BegalDRAFT_2608	3.716e-44	163.0	COG0256@1|root,COG0256@2|Bacteria,1RGY7@1224|Proteobacteria,1S5V2@1236|Gammaproteobacteria,460WC@72273|Thiotrichales	72273|Thiotrichales	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
CMS1_k127_1835984_7	1177181.T9A_02929	1.754e-68	236.0	COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,1S1Z1@1236|Gammaproteobacteria,1XJA3@135619|Oceanospirillales	135619|Oceanospirillales	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
CMS1_k127_1835984_15	396588.Tgr7_2310	1.4e-49	179.0	COG0096@1|root,COG0096@2|Bacteria,1RDG3@1224|Proteobacteria,1S452@1236|Gammaproteobacteria,1WXYT@135613|Chromatiales	135613|Chromatiales	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
CMS1_k127_1835984_20	999141.GME_13285	2.664e-37	142.0	COG0199@1|root,COG0199@2|Bacteria,1MZDT@1224|Proteobacteria,1S62N@1236|Gammaproteobacteria,1XKDP@135619|Oceanospirillales	135619|Oceanospirillales	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
CMS1_k127_1835984_4	1121004.ATVC01000003_gene515	1.277e-86	289.0	COG0094@1|root,COG0094@2|Bacteria,1MUU9@1224|Proteobacteria,2VHCP@28216|Betaproteobacteria,2KPPI@206351|Neisseriales	206351|Neisseriales	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
CMS1_k127_1835984_19	1049564.TevJSym_aa00130	1.256e-39	150.0	COG0198@1|root,COG0198@2|Bacteria,1MZQD@1224|Proteobacteria,1S973@1236|Gammaproteobacteria,1J6C1@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
CMS1_k127_1835984_11	395493.BegalDRAFT_2614	9.973e-65	224.0	COG0093@1|root,COG0093@2|Bacteria,1RCWZ@1224|Proteobacteria,1S3Z3@1236|Gammaproteobacteria,460HS@72273|Thiotrichales	72273|Thiotrichales	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
CMS1_k127_1835984_21	395493.BegalDRAFT_2615	2.365e-26	110.0	COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,1S8SS@1236|Gammaproteobacteria,4613R@72273|Thiotrichales	72273|Thiotrichales	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
CMS1_k127_1835984_24	697282.Mettu_1325	4.198e-19	89.0	COG0255@1|root,COG0255@2|Bacteria,1N6PR@1224|Proteobacteria,1SCBN@1236|Gammaproteobacteria,1XFTH@135618|Methylococcales	135618|Methylococcales	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
CMS1_k127_1835984_10	765913.ThidrDRAFT_1744	4.222e-66	228.0	COG0197@1|root,COG0197@2|Bacteria,1RA0Z@1224|Proteobacteria,1S201@1236|Gammaproteobacteria,1WY6U@135613|Chromatiales	135613|Chromatiales	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
CMS1_k127_1835984_2	857087.Metme_3810	6.03e-107	350.0	COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,1RN0P@1236|Gammaproteobacteria,1XEGS@135618|Methylococcales	135618|Methylococcales	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
CMS1_k127_1835984_18	396588.Tgr7_2319	1.518e-42	159.0	COG0091@1|root,COG0091@2|Bacteria,1RH0W@1224|Proteobacteria,1S5XT@1236|Gammaproteobacteria,1WYH7@135613|Chromatiales	135613|Chromatiales	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
CMS1_k127_1835984_17	377629.TERTU_0912	7.267e-43	158.0	COG0185@1|root,COG0185@2|Bacteria,1RGYX@1224|Proteobacteria,1S5VT@1236|Gammaproteobacteria,2PNTZ@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	J	Ribosomal protein S19	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
CMS1_k127_1835984_1	751994.AGIG01000002_gene920	4.823e-137	439.0	COG0090@1|root,COG0090@2|Bacteria,1MVTD@1224|Proteobacteria,1RMGR@1236|Gammaproteobacteria,1J4FI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
CMS1_k127_1835984_22	697282.Mettu_1331	2.064e-25	109.0	COG0089@1|root,COG0089@2|Bacteria,1MZXX@1224|Proteobacteria,1S8VX@1236|Gammaproteobacteria,1XFJR@135618|Methylococcales	135618|Methylococcales	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
CMS1_k127_1835984_6	349124.Hhal_0857	1.696e-72	251.0	COG0088@1|root,COG0088@2|Bacteria,1MXPF@1224|Proteobacteria,1RNNK@1236|Gammaproteobacteria,1WW16@135613|Chromatiales	135613|Chromatiales	J	Forms part of the polypeptide exit tunnel	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
CMS1_k127_1835984_5	396588.Tgr7_2324	5.394e-84	283.0	COG0087@1|root,COG0087@2|Bacteria,1MUST@1224|Proteobacteria,1RMK9@1236|Gammaproteobacteria,1WVZS@135613|Chromatiales	135613|Chromatiales	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
CMS1_k127_1835984_13	323261.Noc_2325	2.604e-52	185.0	COG0051@1|root,COG0051@2|Bacteria,1RGWF@1224|Proteobacteria,1S3QX@1236|Gammaproteobacteria,1WYRW@135613|Chromatiales	135613|Chromatiales	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
CMS1_k127_1835984_26	1479237.JMLY01000001_gene1165	4.698e-13	68.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,1RMYX@1236|Gammaproteobacteria,4651Q@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
CMS1_k127_1917990_5	1042377.AFPJ01000051_gene110	9.764e-05	46.0	COG0598@1|root,COG0598@2|Bacteria,1MWMP@1224|Proteobacteria,1RNDQ@1236|Gammaproteobacteria,465JG@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	Mediates influx of magnesium ions	corA	GO:0000041,GO:0003674,GO:0005215,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0008150,GO:0008324,GO:0015075,GO:0015087,GO:0015095,GO:0015099,GO:0015318,GO:0015675,GO:0015693,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0035444,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:1903830	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	iYL1228.KPN_04313	CorA
CMS1_k127_1917990_2	1232410.KI421413_gene761	1e-56	202.0	COG2716@1|root,COG2716@2|Bacteria,1Q2TM@1224|Proteobacteria,42W89@68525|delta/epsilon subdivisions,2WSEF@28221|Deltaproteobacteria,43V1Y@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	ACT domain	-	-	-	-	-	-	-	-	-	-	-	-	ACT_6
CMS1_k127_1917990_4	285535.JOEY01000024_gene276	2.702e-25	118.0	2BEG0@1|root,3287A@2|Bacteria,2HDZC@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1917990_3	909663.KI867151_gene3075	2.339e-41	159.0	2FDXX@1|root,345Y9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1917990_1	909663.KI867151_gene3076	4.374e-59	214.0	COG4385@1|root,COG4385@2|Bacteria,1R7X6@1224|Proteobacteria,42QDW@68525|delta/epsilon subdivisions,2WK0S@28221|Deltaproteobacteria,2MSG8@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Phage tail protein (Tail_P2_I)	-	-	-	-	-	-	-	-	-	-	-	-	Tail_P2_I
CMS1_k127_1929929_5	472759.Nhal_3572	9e-26	108.0	COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,1RQU0@1236|Gammaproteobacteria,1WW93@135613|Chromatiales	135613|Chromatiales	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
CMS1_k127_1929929_1	765912.Thimo_1834	4.674e-71	248.0	COG2231@1|root,COG2231@2|Bacteria,1RDJ8@1224|Proteobacteria,1RUHP@1236|Gammaproteobacteria,1WXXG@135613|Chromatiales	135613|Chromatiales	L	PFAM HhH-GPD	-	-	-	ko:K07457	-	-	-	-	ko00000	-	-	-	HhH-GPD
CMS1_k127_1929929_0	396588.Tgr7_0984	1.113e-94	316.0	COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,1RM8I@1236|Gammaproteobacteria,1WW6U@135613|Chromatiales	135613|Chromatiales	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
CMS1_k127_1929929_6	1123400.KB904769_gene2810	3.372e-24	108.0	COG1314@1|root,COG1314@2|Bacteria,1N8MF@1224|Proteobacteria,1SD3P@1236|Gammaproteobacteria,46176@72273|Thiotrichales	72273|Thiotrichales	U	Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
CMS1_k127_1929929_4	1392838.AWNM01000017_gene3532	1.244e-32	132.0	COG1569@1|root,COG1569@2|Bacteria,1PUMJ@1224|Proteobacteria,2VV5E@28216|Betaproteobacteria,3T7QN@506|Alcaligenaceae	28216|Betaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
CMS1_k127_1929929_8	278963.ATWD01000001_gene1317	1.023e-17	84.0	COG2336@1|root,COG2336@2|Bacteria	2|Bacteria	T	PFAM SpoVT AbrB	-	-	-	ko:K07172,ko:K18842	-	-	-	-	ko00000,ko02048	-	-	-	MazE_antitoxin
CMS1_k127_1929929_2	323261.Noc_2696	1.619e-54	196.0	2EE49@1|root,337YY@2|Bacteria,1NE01@1224|Proteobacteria,1SUGH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Cytochrome P460	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_P460
CMS1_k127_1929929_3	296591.Bpro_3256	8.068e-51	182.0	COG0838@1|root,COG0838@2|Bacteria,1RGUT@1224|Proteobacteria,2VSI3@28216|Betaproteobacteria,4AE1G@80864|Comamonadaceae	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
CMS1_k127_1929929_7	365046.Rta_26420	1.387e-20	91.0	COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,2VIWK@28216|Betaproteobacteria,4ACEJ@80864|Comamonadaceae	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
CMS1_k127_1948816_3	279714.FuraDRAFT_0338	2.654e-265	822.0	COG4263@1|root,COG4263@2|Bacteria,1MVIH@1224|Proteobacteria,2VM8J@28216|Betaproteobacteria,2KQNM@206351|Neisseriales	206351|Neisseriales	C	Cytochrome C oxidase subunit II, periplasmic domain protein	nosZ	-	1.7.2.4	ko:K00376	ko00910,ko01120,map00910,map01120	M00529	R02804	RC02861	ko00000,ko00001,ko00002,ko01000	-	-	-	-
CMS1_k127_1948816_1	1123393.KB891326_gene120	0.0	1101.0	COG0348@1|root,COG3901@1|root,COG0348@2|Bacteria,COG3901@2|Bacteria,1MY5M@1224|Proteobacteria,2VH7V@28216|Betaproteobacteria,1KSED@119069|Hydrogenophilales	119069|Hydrogenophilales	CK	FMN_bind	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind,Fer4_5
CMS1_k127_1948816_5	1132855.KB913035_gene1597	1.205e-172	552.0	COG3420@1|root,COG3420@2|Bacteria,1MVCD@1224|Proteobacteria,2VIYN@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Periplasmic copper-binding	nosD	-	-	ko:K07218	-	-	-	-	ko00000	-	-	-	NosD
CMS1_k127_1948816_14	983917.RGE_19180	2.402e-91	312.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,2VKGA@28216|Betaproteobacteria,1KN21@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	nosF	-	-	ko:K19340	ko02010,map02010	M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.132.2	-	-	ABC_tran
CMS1_k127_1948816_13	1123392.AQWL01000003_gene158	5.562e-101	337.0	COG1277@1|root,COG1277@2|Bacteria,1MWUZ@1224|Proteobacteria,2VJDE@28216|Betaproteobacteria,1KS18@119069|Hydrogenophilales	119069|Hydrogenophilales	S	ABC-2 family transporter protein	-	-	-	ko:K19341	ko02010,map02010	M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.132.2	-	-	ABC2_membrane_2
CMS1_k127_1948816_20	266264.Rmet_4912	8.466e-51	189.0	COG4314@1|root,COG4314@2|Bacteria,1RCDR@1224|Proteobacteria,2VIGY@28216|Betaproteobacteria,1K5MC@119060|Burkholderiaceae	28216|Betaproteobacteria	C	NosL	nosL	-	-	ko:K19342	-	-	-	-	ko00000	-	-	-	NosL
CMS1_k127_1948816_12	1123256.KB907945_gene349	1.233e-106	351.0	COG0546@1|root,COG0546@2|Bacteria,1Q5AX@1224|Proteobacteria,1RRNJ@1236|Gammaproteobacteria,1X9C4@135614|Xanthomonadales	135614|Xanthomonadales	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
CMS1_k127_1948816_15	392500.Swoo_2359	4.123e-86	301.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,1RQAA@1236|Gammaproteobacteria,2QEJZ@267890|Shewanellaceae	1236|Gammaproteobacteria	M	PFAM peptidase S8 and S53 subtilisin kexin sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
CMS1_k127_1948816_19	713586.KB900536_gene1140	1.474e-61	215.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,1S3WP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
CMS1_k127_1948816_11	396588.Tgr7_2294	1.053e-107	364.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,1RN70@1236|Gammaproteobacteria,1WXE2@135613|Chromatiales	135613|Chromatiales	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
CMS1_k127_1948816_0	519989.ECTPHS_03076	0.0	1435.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,1RMS9@1236|Gammaproteobacteria,1WX68@135613|Chromatiales	135613|Chromatiales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
CMS1_k127_1948816_7	1340493.JNIF01000003_gene3109	3.071e-137	451.0	COG2133@1|root,COG2133@2|Bacteria,3Y3YZ@57723|Acidobacteria	57723|Acidobacteria	G	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
CMS1_k127_1948816_6	395493.BegalDRAFT_3524	4.376e-152	485.0	COG0524@1|root,COG0524@2|Bacteria,1QTMS@1224|Proteobacteria,1RQQY@1236|Gammaproteobacteria,460BF@72273|Thiotrichales	72273|Thiotrichales	G	PFAM pfkB family carbohydrate kinase	-	-	2.7.1.20	ko:K00856	ko00230,ko01100,map00230,map01100	-	R00185	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
CMS1_k127_1948816_16	1244869.H261_18582	1.589e-85	292.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,2TR2I@28211|Alphaproteobacteria	1224|Proteobacteria	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
CMS1_k127_1948816_17	1395571.TMS3_0114015	2.077e-74	263.0	COG0753@1|root,COG0753@2|Bacteria,1RC6W@1224|Proteobacteria,1S3BQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Catalase	-	-	-	-	-	-	-	-	-	-	-	-	Catalase
CMS1_k127_1948816_9	1056820.KB900663_gene3824	1.264e-118	404.0	COG1858@1|root,COG1858@2|Bacteria,1QVCJ@1224|Proteobacteria,1T31G@1236|Gammaproteobacteria,2PQ7W@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	P	cytochrome C peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1948816_8	1177181.T9A_00609	1.115e-127	423.0	COG1075@1|root,COG1075@2|Bacteria,1NGMF@1224|Proteobacteria	1224|Proteobacteria	S	Lecithin:cholesterol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	LCAT
CMS1_k127_1948816_10	977880.RALTA_B1917	5.485e-117	383.0	COG2354@1|root,COG2354@2|Bacteria,1MVYU@1224|Proteobacteria,2VHTU@28216|Betaproteobacteria,1KC32@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF808)	yedI	-	-	ko:K09781	-	-	-	-	ko00000	-	-	-	DUF808
CMS1_k127_1948816_22	66874.JOFS01000019_gene7842	1.438e-14	79.0	COG3193@1|root,COG3193@2|Bacteria,2IHWI@201174|Actinobacteria	201174|Actinobacteria	S	protein possibly involved in utilization of glycolate and propanediol	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
CMS1_k127_1948816_2	479433.Caci_0734	1.336e-288	895.0	COG1274@1|root,COG1274@2|Bacteria,2GJH3@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009607,GO:0009987,GO:0009991,GO:0010106,GO:0016020,GO:0019725,GO:0030003,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042592,GO:0042594,GO:0043207,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071496,GO:0071944,GO:0075136,GO:0098771	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
CMS1_k127_1948816_4	323261.Noc_2549	2.231e-255	804.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,1RSQQ@1236|Gammaproteobacteria,1WWA4@135613|Chromatiales	135613|Chromatiales	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
CMS1_k127_1948816_21	754477.Q7C_95	1.687e-36	142.0	COG4633@1|root,COG4633@2|Bacteria,1N6VB@1224|Proteobacteria,1SDG5@1236|Gammaproteobacteria,4619I@72273|Thiotrichales	72273|Thiotrichales	S	Cupredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
CMS1_k127_1948816_18	1232683.ADIMK_4084	4.47e-63	222.0	COG0672@1|root,COG0672@2|Bacteria	2|Bacteria	P	high-affinity ferrous iron transmembrane transporter activity	-	-	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	FTR1
CMS1_k127_1977521_69	1123355.JHYO01000016_gene1911	2.139e-12	76.0	COG4254@1|root,COG4254@2|Bacteria,1N3NK@1224|Proteobacteria,2TV69@28211|Alphaproteobacteria,36Z1G@31993|Methylocystaceae	28211|Alphaproteobacteria	S	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
CMS1_k127_1977521_45	85643.Tmz1t_1979	1.044e-66	239.0	COG1073@1|root,COG1073@2|Bacteria,1R8S6@1224|Proteobacteria,2VMN1@28216|Betaproteobacteria,2KYMU@206389|Rhodocyclales	206389|Rhodocyclales	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1977521_58	1244869.H261_10039	5.365e-31	139.0	COG4625@1|root,COG4625@2|Bacteria,1NGYG@1224|Proteobacteria,2UMI6@28211|Alphaproteobacteria,2JWEX@204441|Rhodospirillales	204441|Rhodospirillales	S	Autotransporter beta-domain	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter
CMS1_k127_1977521_67	1150621.SMUL_2892	9.35e-13	71.0	COG3585@1|root,COG3585@2|Bacteria,1P6UA@1224|Proteobacteria,432HS@68525|delta/epsilon subdivisions	1224|Proteobacteria	H	TOBE domain	-	-	-	-	-	-	-	-	-	-	-	-	TOBE
CMS1_k127_1977521_48	1177181.T9A_00915	1.287e-56	206.0	COG5429@1|root,COG5429@2|Bacteria,1MW6R@1224|Proteobacteria,1S834@1236|Gammaproteobacteria,1XK62@135619|Oceanospirillales	135619|Oceanospirillales	S	secreted protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1223
CMS1_k127_1977521_3	159450.NH14_09550	1.774e-299	944.0	COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,2VIG4@28216|Betaproteobacteria,1KDBG@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Phosphoenolpyruvate carboxylase	-	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
CMS1_k127_1977521_30	1449351.RISW2_16590	8.143e-110	363.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,2TSM8@28211|Alphaproteobacteria,4KKCK@93682|Roseivivax	28211|Alphaproteobacteria	CH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	gyaR2	-	1.1.1.215,1.1.1.26,1.1.1.79,1.1.1.81	ko:K00015,ko:K00050,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	-	R00465,R00717,R01388,R01392,R01739	RC00031,RC00042,RC00084	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
CMS1_k127_1977521_22	1317118.ATO8_19734	9.284e-145	463.0	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,2TTC8@28211|Alphaproteobacteria,4KKA1@93682|Roseivivax	28211|Alphaproteobacteria	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	mtkB	-	6.2.1.5,6.2.1.9	ko:K01902,ko:K08692	ko00020,ko00630,ko00640,ko00660,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00630,map00640,map00660,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00346,M00374,M00620	R00405,R01256,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
CMS1_k127_1977521_8	1122135.KB893134_gene3555	1.187e-193	610.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,2TRXK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	mtkA	-	6.2.1.5,6.2.1.9	ko:K01903,ko:K14067	ko00020,ko00630,ko00640,ko00660,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00630,map00640,map00660,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00346,M00374,M00620	R00405,R01256,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
CMS1_k127_1977521_26	394.NGR_c26230	1.612e-136	444.0	COG2301@1|root,COG2301@2|Bacteria,1MW0A@1224|Proteobacteria,2TU4H@28211|Alphaproteobacteria,4BCRG@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	HpcH/HpaI aldolase/citrate lyase family	-	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
CMS1_k127_1977521_17	1380391.JIAS01000012_gene4035	1.68e-160	514.0	COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,2TQSN@28211|Alphaproteobacteria,2JQ78@204441|Rhodospirillales	204441|Rhodospirillales	E	Aminotransferase class-V	-	-	2.6.1.44,2.6.1.45,2.6.1.51	ko:K00830	ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	M00346,M00532	R00369,R00372,R00585,R00588	RC00006,RC00008,RC00018	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
CMS1_k127_1977521_15	768671.ThimaDRAFT_3681	5.642e-173	550.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,1RMCV@1236|Gammaproteobacteria,1WWGS@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	metZ	-	-	ko:K10764	ko00270,ko00920,ko01100,map00270,map00920,map01100	-	R01288	RC00020,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
CMS1_k127_1977521_5	1116472.MGMO_37c00150	4.589e-218	683.0	COG0538@1|root,COG0538@2|Bacteria,1MW3J@1224|Proteobacteria,1RNMD@1236|Gammaproteobacteria,1XEUJ@135618|Methylococcales	135618|Methylococcales	C	Isocitrate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Iso_dh
CMS1_k127_1977521_23	926550.CLDAP_31550	2.014e-142	471.0	COG4579@1|root,COG4579@2|Bacteria	2|Bacteria	F	[isocitrate dehydrogenase (NADP+)] phosphatase activity	aceK	GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004721,GO:0004722,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008772,GO:0009060,GO:0009987,GO:0015980,GO:0016208,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0016999,GO:0017076,GO:0017144,GO:0018105,GO:0018193,GO:0018209,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0036211,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046487,GO:0050790,GO:0055114,GO:0065007,GO:0065009,GO:0070262,GO:0071704,GO:0072350,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564	2.7.11.5	ko:K00906	-	-	-	-	ko00000,ko01000	-	-	-	AceK
CMS1_k127_1977521_74	159087.Daro_1865	0.0007066	46.0	2EC8Y@1|root,3367B@2|Bacteria,1NFHG@1224|Proteobacteria,2VWKX@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1977521_38	1122604.JONR01000007_gene2869	9.224e-97	321.0	COG1187@1|root,COG1187@2|Bacteria,1MXQE@1224|Proteobacteria,1RMC7@1236|Gammaproteobacteria,1X338@135614|Xanthomonadales	135614|Xanthomonadales	J	Belongs to the pseudouridine synthase RsuA family	rluF	-	5.4.99.21	ko:K06182	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
CMS1_k127_1977521_60	351607.Acel_1033	5.328e-28	117.0	COG4747@1|root,COG4747@2|Bacteria	2|Bacteria	-	-	hom	-	1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19	ko:K00003,ko:K00058,ko:K01754,ko:K04767	ko00260,ko00270,ko00290,ko00300,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00290,map00300,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00017,M00018,M00020,M00570	R00220,R00996,R01513,R01773,R01775	RC00031,RC00087,RC00418,RC02600	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT,CBS,Homoserine_dh,Lactamase_B,NAD_binding_3
CMS1_k127_1977521_31	1049564.TevJSym_ar00210	7.539e-109	364.0	COG0477@1|root,COG2814@2|Bacteria,1MVZI@1224|Proteobacteria,1RPBT@1236|Gammaproteobacteria,1J4X2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	EGP	Nucleoside H+ symporter	hcaT	-	-	ko:K05820	-	-	-	-	ko00000,ko02000	2.A.1.27	-	-	MFS_1_like
CMS1_k127_1977521_9	396588.Tgr7_1241	4.531e-192	604.0	COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,1RMQS@1236|Gammaproteobacteria,1WXNW@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
CMS1_k127_1977521_65	555778.Hneap_0738	4.059e-15	83.0	COG0526@1|root,COG0526@2|Bacteria,1N726@1224|Proteobacteria,1SD4C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	CO	COG0526 Thiol-disulfide isomerase and thioredoxins	resA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS1_k127_1977521_20	1538295.JY96_04550	7e-147	473.0	COG3177@1|root,COG3177@2|Bacteria,1MV69@1224|Proteobacteria,2VIY1@28216|Betaproteobacteria,1KMFQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Fic/DOC family N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Fic_N
CMS1_k127_1977521_70	1487953.JMKF01000009_gene6136	8.473e-11	64.0	2EHB5@1|root,33B30@2|Bacteria,1GEAV@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1977521_54	420662.Mpe_A2087	5.207e-50	186.0	COG2010@1|root,COG2010@2|Bacteria,1QVK1@1224|Proteobacteria,2WHT1@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrome_CBB3
CMS1_k127_1977521_11	670307.HYPDE_31933	5.126e-187	594.0	COG2041@1|root,COG2041@2|Bacteria,1MX9E@1224|Proteobacteria,2TRK0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	COG2041 Sulfite oxidase and related enzymes	soxC	-	-	ko:K17225	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	Mo-co_dimer,Oxidored_molyb
CMS1_k127_1977521_39	1297865.APJD01000006_gene4543	1.37e-95	318.0	COG2020@1|root,COG2020@2|Bacteria,1MWU6@1224|Proteobacteria,2TU80@28211|Alphaproteobacteria,3JQR6@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	methyltransferase activity	-	-	2.1.1.334	ko:K21310	ko00920,map00920	-	R11546	RC02653	ko00000,ko00001,ko01000	-	-	-	NnrU,PEMT
CMS1_k127_1977521_37	1122194.AUHU01000002_gene2557	7.5e-98	329.0	COG2890@1|root,COG2890@2|Bacteria,1MX8Q@1224|Proteobacteria,1RPHQ@1236|Gammaproteobacteria,464PR@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue	prmB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006304,GO:0006305,GO:0006306,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009007,GO:0009008,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0032775,GO:0034641,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044728,GO:0046483,GO:0071704,GO:0090304,GO:0140096,GO:0140097,GO:1901360,GO:1901564	2.1.1.298	ko:K07320	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03009	-	-	-	MTS
CMS1_k127_1977521_7	82654.Pse7367_3306	9.337e-194	618.0	COG2203@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,1GQI2@1117|Cyanobacteria	1117|Cyanobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_5
CMS1_k127_1977521_4	472759.Nhal_2092	2.591e-258	813.0	COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,1RNWD@1236|Gammaproteobacteria,1WW6M@135613|Chromatiales	135613|Chromatiales	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
CMS1_k127_1977521_66	323850.Shew_0640	6.766e-14	78.0	COG0457@1|root,COG0457@2|Bacteria,1NHI4@1224|Proteobacteria,1SH4R@1236|Gammaproteobacteria,2QC0Y@267890|Shewanellaceae	1236|Gammaproteobacteria	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16
CMS1_k127_1977521_2	472759.Nhal_1115	0.0	1015.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,1RNW3@1236|Gammaproteobacteria,1WVV0@135613|Chromatiales	135613|Chromatiales	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
CMS1_k127_1977521_52	1211114.ALIP01000113_gene878	5.742e-53	188.0	COG1146@1|root,COG1146@2|Bacteria,1RH5I@1224|Proteobacteria,1S5ZK@1236|Gammaproteobacteria,1X6V9@135614|Xanthomonadales	135614|Xanthomonadales	C	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions	VM57_07835	-	-	ko:K05524	-	-	-	-	ko00000	-	-	-	DUF3470,Fer4
CMS1_k127_1977521_43	391615.ABSJ01000026_gene113	7.301e-74	258.0	COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,1SZ5G@1236|Gammaproteobacteria,1JBU3@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2,SpoIIE
CMS1_k127_1977521_44	391615.ABSJ01000026_gene114	1.009e-72	252.0	COG1716@1|root,COG1716@2|Bacteria,1MW1M@1224|Proteobacteria,1S50X@1236|Gammaproteobacteria,1J761@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
CMS1_k127_1977521_61	2340.JV46_19880	3.823e-27	119.0	COG3218@1|root,COG3218@2|Bacteria,1N13E@1224|Proteobacteria	1224|Proteobacteria	S	ABC-type transport auxiliary lipoprotein component	-	-	-	ko:K18480	-	M00669	-	-	ko00000,ko00002,ko02000	3.A.1.27.1	-	-	ABC_trans_aux
CMS1_k127_1977521_50	1238182.C882_0832	7.995e-55	205.0	COG1463@1|root,COG1463@2|Bacteria,1RCV1@1224|Proteobacteria,2U6E9@28211|Alphaproteobacteria,2JRVS@204441|Rhodospirillales	204441|Rhodospirillales	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
CMS1_k127_1977521_32	1123355.JHYO01000008_gene2684	1.821e-107	357.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,2TR2I@28211|Alphaproteobacteria,36XHC@31993|Methylocystaceae	28211|Alphaproteobacteria	Q	ATPases associated with a variety of cellular activities	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
CMS1_k127_1977521_40	2340.JV46_19840	7.292e-93	313.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,1SKTY@1236|Gammaproteobacteria,1JA8F@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	Q	Permease MlaE	-	-	-	-	-	-	-	-	-	-	-	-	MlaE
CMS1_k127_1977521_59	1049564.TevJSym_ac01830	3.105e-28	117.0	COG1366@1|root,COG1366@2|Bacteria,1N6U1@1224|Proteobacteria,1SJ1P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Anti-sigma-factor antagonist	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
CMS1_k127_1977521_18	2340.JV46_19820	3.467e-151	496.0	COG2172@1|root,COG2203@1|root,COG2208@1|root,COG2172@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,1MXJQ@1224|Proteobacteria,1RQIY@1236|Gammaproteobacteria,1JA7R@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	GAF,GAF_2,HATPase_c_2,PAS,SpoIIE
CMS1_k127_1977521_36	593105.S7A_10305	7.109e-99	326.0	COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,1RMHU@1236|Gammaproteobacteria,3VZKV@53335|Pantoea	1236|Gammaproteobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	GO:0000702,GO:0000703,GO:0003674,GO:0003824,GO:0003906,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0034644,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071214,GO:0071478,GO:0071482,GO:0071704,GO:0090304,GO:0104004,GO:0140097,GO:1901360	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
CMS1_k127_1977521_62	1286106.MPL1_08534	2.242e-17	89.0	COG4660@1|root,COG4660@2|Bacteria,1MW6N@1224|Proteobacteria,1RMEH@1236|Gammaproteobacteria,45ZVS@72273|Thiotrichales	72273|Thiotrichales	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03613	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
CMS1_k127_1977521_71	926560.KE387023_gene2029	3.902e-08	57.0	COG4269@1|root,COG4269@2|Bacteria,1WM8M@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Bacterial protein of unknown function (DUF898)	-	-	-	-	-	-	-	-	-	-	-	-	DUF898
CMS1_k127_1977521_47	402881.Plav_2072	2.601e-60	213.0	COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,2U58D@28211|Alphaproteobacteria,1JNWH@119043|Rhodobiaceae	28211|Alphaproteobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
CMS1_k127_1977521_21	530564.Psta_0494	7.261e-145	468.0	COG0026@1|root,COG0026@2|Bacteria,2IXNU@203682|Planctomycetes	203682|Planctomycetes	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
CMS1_k127_1977521_27	857087.Metme_4597	2.499e-121	400.0	COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,1RPYA@1236|Gammaproteobacteria,1XDVA@135618|Methylococcales	135618|Methylococcales	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
CMS1_k127_1977521_53	395493.BegalDRAFT_3005	4.577e-51	189.0	COG2802@1|root,COG2802@2|Bacteria,1RFYH@1224|Proteobacteria,1S54H@1236|Gammaproteobacteria,462T3@72273|Thiotrichales	72273|Thiotrichales	S	ATP-dependent protease La (LON) substrate-binding domain	-	-	-	ko:K07157	-	-	-	-	ko00000	-	-	-	LON_substr_bdg
CMS1_k127_1977521_13	1294143.H681_04060	1.35e-177	567.0	COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,1RMMT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate	mpl	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS1_k127_1977521_29	243160.BMAA0795	3.456e-115	384.0	COG0019@1|root,COG4638@1|root,COG0019@2|Bacteria,COG4638@2|Bacteria,1MW3T@1224|Proteobacteria,2VR86@28216|Betaproteobacteria,1KE46@119060|Burkholderiaceae	28216|Betaproteobacteria	EP	Pyridoxal-dependent decarboxylase, C-terminal sheet domain	nspC	-	4.1.1.96	ko:K13747	ko00330,ko01100,map00330,map01100	-	R09081,R09082	RC00299	ko00000,ko00001,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC,Rieske,Ring_hydroxyl_A
CMS1_k127_1977521_46	187272.Mlg_0427	1.806e-62	221.0	COG0494@1|root,COG0494@2|Bacteria,1RDGJ@1224|Proteobacteria,1S3PQ@1236|Gammaproteobacteria,1WXC4@135613|Chromatiales	135613|Chromatiales	L	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage	nudH	-	-	ko:K08311	ko03018,map03018	-	R10816	RC00002	ko00000,ko00001,ko01000,ko03019	-	-	-	NUDIX
CMS1_k127_1977521_42	1288826.MSNKSG1_18215	1.071e-75	260.0	COG0560@1|root,COG0560@2|Bacteria,1RA1A@1224|Proteobacteria,1S21J@1236|Gammaproteobacteria,466GA@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	COG0560 Phosphoserine phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
CMS1_k127_1977521_25	1117647.M5M_03600	3.663e-141	456.0	COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,1RMAX@1236|Gammaproteobacteria,1J4DY@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072350,GO:0072524,GO:1901360,GO:1901564	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
CMS1_k127_1977521_0	472759.Nhal_0099	0.0	1190.0	COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,1RN8K@1236|Gammaproteobacteria,1WWM2@135613|Chromatiales	135613|Chromatiales	C	Dehydrogenase E1 component	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
CMS1_k127_1977521_19	349124.Hhal_1085	1.385e-147	480.0	COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,1RME0@1236|Gammaproteobacteria,1WXGA@135613|Chromatiales	135613|Chromatiales	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
CMS1_k127_1977521_14	1278309.KB907101_gene543	9.857e-174	556.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RMFF@1236|Gammaproteobacteria,1XH5E@135619|Oceanospirillales	135619|Oceanospirillales	C	2-oxoglutarate dehydrogenase complex	lpdG	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
CMS1_k127_1977521_73	702113.PP1Y_Mpl7969	0.0004557	49.0	COG4319@1|root,COG4319@2|Bacteria,1N361@1224|Proteobacteria,2UHUN@28211|Alphaproteobacteria,2KC0T@204457|Sphingomonadales	204457|Sphingomonadales	M	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
CMS1_k127_1977521_35	243233.MCA2456	2.273e-99	333.0	COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,1RPNX@1236|Gammaproteobacteria,1XGZS@135618|Methylococcales	135618|Methylococcales	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
CMS1_k127_1977521_10	765913.ThidrDRAFT_0217	2.761e-187	591.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,1RM93@1236|Gammaproteobacteria,1WW4A@135613|Chromatiales	135613|Chromatiales	I	Belongs to the thiolase family	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
CMS1_k127_1977521_33	713586.KB900536_gene571	4.696e-105	347.0	COG1028@1|root,COG1028@2|Bacteria,1MUEV@1224|Proteobacteria,1RNH2@1236|Gammaproteobacteria,1WWM8@135613|Chromatiales	135613|Chromatiales	IQ	TIGRFAM acetoacetyl-CoA reductase	-	-	1.1.1.36	ko:K00023	ko00630,ko00650,ko01120,ko01200,map00630,map00650,map01120,map01200	M00373	R01779,R01977	RC00103,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short_C2
CMS1_k127_1977521_55	935863.AWZR01000003_gene2644	8.17e-48	175.0	COG5394@1|root,COG5394@2|Bacteria,1RHRC@1224|Proteobacteria,1S2XX@1236|Gammaproteobacteria,1XC5X@135614|Xanthomonadales	135614|Xanthomonadales	S	synthesis repressor, PhaR	phaR	-	-	-	-	-	-	-	-	-	-	-	PHB_acc,PHB_acc_N
CMS1_k127_1977521_16	713586.KB900536_gene568	1.832e-161	514.0	COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,1RVJU@1236|Gammaproteobacteria,1WXJS@135613|Chromatiales	135613|Chromatiales	I	Poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009058,GO:0016234,GO:0042618,GO:0042619,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0070088,GO:0071704,GO:1901440,GO:1901441,GO:1901576	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
CMS1_k127_1977521_51	572477.Alvin_0062	1.307e-53	203.0	28KIX@1|root,2Z9Y0@2|Bacteria,1R427@1224|Proteobacteria,1RRGI@1236|Gammaproteobacteria,1WX2J@135613|Chromatiales	135613|Chromatiales	S	TIGRFAM Poly(R)-hydroxyalkanoic acid synthase, class III, PhaE subunit	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009058,GO:0016234,GO:0042618,GO:0042619,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0070088,GO:0071704,GO:1901440,GO:1901441,GO:1901576	-	-	-	-	-	-	-	-	-	-	PHA_synth_III_E
CMS1_k127_1977521_1	395493.BegalDRAFT_0251	0.0	1049.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,1RMNZ@1236|Gammaproteobacteria,45ZSH@72273|Thiotrichales	72273|Thiotrichales	I	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
CMS1_k127_1977521_49	1026882.MAMP_01603	4.127e-56	205.0	COG2885@1|root,COG2885@2|Bacteria,1RGHU@1224|Proteobacteria,1S5H8@1236|Gammaproteobacteria,463ME@72273|Thiotrichales	72273|Thiotrichales	M	Belongs to the ompA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OmpA,TSP_3
CMS1_k127_1977521_6	153948.NAL212_1227	2.014e-197	621.0	COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,2VID7@28216|Betaproteobacteria,371RE@32003|Nitrosomonadales	28216|Betaproteobacteria	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
CMS1_k127_1977521_41	1042377.AFPJ01000029_gene561	1.381e-79	271.0	COG0764@1|root,COG0764@2|Bacteria,1MWV8@1224|Proteobacteria,1RP6W@1236|Gammaproteobacteria,4657R@72275|Alteromonadaceae	1236|Gammaproteobacteria	I	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length	fabA	-	4.2.1.59,5.3.3.14	ko:K01716	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07639	RC00831,RC01078,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
CMS1_k127_1977521_12	243233.MCA2879	6.86e-184	582.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,1XDY1@135618|Methylococcales	135618|Methylococcales	IQ	Belongs to the beta-ketoacyl-ACP synthases family	fabB	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
CMS1_k127_1977521_64	1026882.MAMP_02488	8.766e-17	85.0	2CIIQ@1|root,32ZU0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_1977521_24	1499967.BAYZ01000102_gene3560	1.203e-141	460.0	COG1092@1|root,COG1092@2|Bacteria,2NPFM@2323|unclassified Bacteria	2|Bacteria	J	S-adenosylmethionine-dependent methyltransferase	rlmI	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.173,2.1.1.191,2.1.1.264	ko:K06969,ko:K12297	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
CMS1_k127_1977521_28	56107.Cylst_4650	6.366e-120	397.0	COG0654@1|root,COG0654@2|Bacteria,1G27G@1117|Cyanobacteria,1HJMB@1161|Nostocales	1117|Cyanobacteria	CH	PFAM monooxygenase FAD-binding	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
CMS1_k127_1977521_57	179408.Osc7112_2582	2.957e-40	153.0	COG0216@1|root,COG0216@2|Bacteria,1GRA7@1117|Cyanobacteria,1HIB4@1150|Oscillatoriales	1117|Cyanobacteria	J	PFAM Peptide chain release factor class I class II	-	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
CMS1_k127_1977521_56	748247.AZKH_1551	4.123e-46	169.0	COG1403@1|root,COG1403@2|Bacteria,1RGZQ@1224|Proteobacteria,2VSZE@28216|Betaproteobacteria,2KWRE@206389|Rhodocyclales	206389|Rhodocyclales	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH
CMS1_k127_1977521_63	225849.swp_4614	4.441e-17	83.0	2EK1G@1|root,33DRY@2|Bacteria,1NH6C@1224|Proteobacteria,1SGMZ@1236|Gammaproteobacteria,2QCVX@267890|Shewanellaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3012)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3012
CMS1_k127_1977521_34	382464.ABSI01000010_gene3722	1.084e-104	349.0	COG1028@1|root,COG1028@2|Bacteria	382464.ABSI01000010_gene3722|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2074770_6	519989.ECTPHS_05345	4.224e-82	278.0	COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,1RQU0@1236|Gammaproteobacteria,1WW93@135613|Chromatiales	135613|Chromatiales	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
CMS1_k127_2074770_8	713586.KB900536_gene604	2.117e-64	228.0	COG1386@1|root,COG1386@2|Bacteria,1PUA6@1224|Proteobacteria,1RNXE@1236|Gammaproteobacteria,1WW3N@135613|Chromatiales	135613|Chromatiales	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
CMS1_k127_2074770_4	396588.Tgr7_2013	5.076e-95	319.0	COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,1RNBB@1236|Gammaproteobacteria,1WW4R@135613|Chromatiales	135613|Chromatiales	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	-	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
CMS1_k127_2074770_1	713586.KB900536_gene602	1.198e-204	642.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,1RNDC@1236|Gammaproteobacteria,1WW43@135613|Chromatiales	135613|Chromatiales	J	TIGRFAM Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
CMS1_k127_2074770_5	498211.CJA_1797	5.341e-89	297.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,1RNU8@1236|Gammaproteobacteria,1FGB4@10|Cellvibrio	1236|Gammaproteobacteria	J	Telomere recombination	yciO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Sua5_yciO_yrdC
CMS1_k127_2074770_11	227377.CBU_0908	2.536e-52	190.0	COG2917@1|root,COG2917@2|Bacteria,1NWIZ@1224|Proteobacteria,1RQAB@1236|Gammaproteobacteria,1JC9T@118969|Legionellales	118969|Legionellales	D	probably involved in intracellular septation	yciB	-	-	ko:K06190	-	-	-	-	ko00000	-	-	-	IspA
CMS1_k127_2074770_12	1123279.ATUS01000001_gene915	2.254e-46	168.0	COG2350@1|root,COG2350@2|Bacteria,1MZ9Z@1224|Proteobacteria,1S8UC@1236|Gammaproteobacteria,1J6PB@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	yciI	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K05527,ko:K09780	-	-	-	-	ko00000,ko03000	-	-	-	YCII
CMS1_k127_2074770_14	84531.JMTZ01000011_gene3088	1.645e-26	111.0	COG0271@1|root,COG0271@2|Bacteria,1QCDM@1224|Proteobacteria,1RTFD@1236|Gammaproteobacteria,1X7ES@135614|Xanthomonadales	135614|Xanthomonadales	T	Belongs to the BolA IbaG family	-	-	-	ko:K05527	-	-	-	-	ko00000,ko03000	-	-	-	BolA
CMS1_k127_2074770_3	1048834.TC41_2963	4.952e-97	324.0	COG0338@1|root,COG0338@2|Bacteria,1TRDX@1239|Firmicutes,4HDFS@91061|Bacilli	91061|Bacilli	L	Site-specific DNA-methyltransferase (Adenine-specific)	dpnM	-	2.1.1.72	ko:K06223	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	-	-	-	MethyltransfD12
CMS1_k127_2074770_2	1123399.AQVE01000007_gene1162	1.849e-160	513.0	COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,1RMNQ@1236|Gammaproteobacteria,460BJ@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls	dapE	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
CMS1_k127_2074770_13	1163409.UUA_02261	1.802e-31	126.0	COG3654@1|root,COG3654@2|Bacteria,1N1FW@1224|Proteobacteria,1SFPB@1236|Gammaproteobacteria,1X6IG@135614|Xanthomonadales	135614|Xanthomonadales	S	Death-on-curing protein	doc	-	-	ko:K07341	-	-	-	-	ko00000,ko02048	-	-	-	Fic
CMS1_k127_2074770_0	1265313.HRUBRA_01681	1.514e-272	844.0	COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,1MUV9@1224|Proteobacteria,1RN8U@1236|Gammaproteobacteria,1J4X4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Catalyzes the reversible hydration of fumarate to (S)- malate	fumA	GO:0003674,GO:0003824,GO:0004333,GO:0005488,GO:0005515,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016860,GO:0016862,GO:0016999,GO:0017144,GO:0019752,GO:0033554,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0047808,GO:0048037,GO:0050163,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0055114,GO:0071704,GO:0072350	4.2.1.2	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	iEC55989_1330.EC55989_1778,iPC815.YPO3335	Fumerase,Fumerase_C
CMS1_k127_2074770_7	663610.JQKO01000005_gene2450	2.409e-69	238.0	COG1607@1|root,COG1607@2|Bacteria,1RAEQ@1224|Proteobacteria,2U6SJ@28211|Alphaproteobacteria,3NC5B@45404|Beijerinckiaceae	28211|Alphaproteobacteria	I	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
CMS1_k127_2074770_15	765913.ThidrDRAFT_2283	6.819e-18	90.0	COG3157@1|root,COG3157@2|Bacteria,1RBTU@1224|Proteobacteria,1S39K@1236|Gammaproteobacteria,1WYR2@135613|Chromatiales	135613|Chromatiales	S	TIGRFAM Type VI secretion system effector, Hcp1	-	-	-	ko:K11903	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	-	-	-	T6SS_HCP
CMS1_k127_2074770_10	1165096.ARWF01000001_gene1700	7.7e-55	194.0	29MCB@1|root,308A4@2|Bacteria,1RFTR@1224|Proteobacteria,2VVTW@28216|Betaproteobacteria,2KNSV@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Putative lumazine-binding	-	-	-	-	-	-	-	-	-	-	-	-	Lumazine_bd_2
CMS1_k127_2074770_9	1380391.JIAS01000011_gene4669	6.276e-62	217.0	2DNBK@1|root,32WMY@2|Bacteria,1R37N@1224|Proteobacteria,2TZZ2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1097)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1097
CMS1_k127_2090150_3	1437882.AZRU01000036_gene256	6.39e-68	251.0	COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1S3Q4@1236|Gammaproteobacteria,1YG4I@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	Q	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,Calx-beta,DUF4114,HemolysinCabind,VWA,VWA_2
CMS1_k127_2090150_1	1198232.CYCME_0394	1.68e-187	604.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1MUQV@1224|Proteobacteria,1RN0Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,LapD_MoxY_N
CMS1_k127_2090150_4	1026882.MAMP_02144	2.689e-67	235.0	COG3672@1|root,COG3672@2|Bacteria,1RDQS@1224|Proteobacteria,1S3Y1@1236|Gammaproteobacteria,460IJ@72273|Thiotrichales	72273|Thiotrichales	S	Bacterial transglutaminase-like cysteine proteinase BTLCP	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C93
CMS1_k127_2090150_5	754476.Q7A_1145	5.934e-17	85.0	2E4XG@1|root,32ZRD@2|Bacteria,1N79W@1224|Proteobacteria,1SCEN@1236|Gammaproteobacteria,461BY@72273|Thiotrichales	72273|Thiotrichales	S	tryptophan synthase subunit beta	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2090150_0	686340.Metal_2566	1.082e-313	975.0	COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,1SBE1@1236|Gammaproteobacteria,1XG1W@135618|Methylococcales	135618|Methylococcales	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
CMS1_k127_2090150_2	686340.Metal_2567	9.092e-73	252.0	COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,1RNK4@1236|Gammaproteobacteria,1XGIM@135618|Methylococcales	135618|Methylococcales	M	TIGRFAM type I secretion membrane fusion protein, HlyD	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
CMS1_k127_2109024_3	1122212.AULO01000014_gene1159	1.834e-254	827.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,1MWVZ@1224|Proteobacteria,1RQBQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	KLT	Serine threonine protein kinase	stk1	-	2.7.11.1	ko:K08282,ko:K11916,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001,ko02044	-	-	-	FGE-sulfatase,Pkinase
CMS1_k127_2109024_24	765912.Thimo_3331	2.127e-68	240.0	COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,1RNPS@1236|Gammaproteobacteria,1WW1D@135613|Chromatiales	135613|Chromatiales	M	PFAM VacJ family lipoprotein	-	-	-	ko:K04754	-	-	-	-	ko00000	-	-	-	MlaA
CMS1_k127_2109024_19	42565.FP66_15220	7.59e-79	269.0	COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,1RMV7@1236|Gammaproteobacteria,1XH4S@135619|Oceanospirillales	135619|Oceanospirillales	H	O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway	ubiG	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_23
CMS1_k127_2109024_22	713586.KB900536_gene583	4.308e-74	258.0	COG0546@1|root,COG0546@2|Bacteria,1RCXJ@1224|Proteobacteria,1S3VU@1236|Gammaproteobacteria,1WXXM@135613|Chromatiales	135613|Chromatiales	S	HAD-superfamily hydrolase, subfamily IA, variant 1	-	-	3.1.3.105	ko:K22292	ko00520,map00520	-	R11785	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
CMS1_k127_2109024_32	396588.Tgr7_1524	5.509e-32	135.0	COG1562@1|root,COG1562@2|Bacteria,1MX4W@1224|Proteobacteria,1RNRI@1236|Gammaproteobacteria,1WYA5@135613|Chromatiales	135613|Chromatiales	I	Squalene phytoene synthase	-	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
CMS1_k127_2109024_39	998674.ATTE01000001_gene1830	0.000394	49.0	COG0694@1|root,COG0694@2|Bacteria,1NHWB@1224|Proteobacteria,1SI9Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins	-	-	-	ko:K19168	-	-	-	-	ko00000,ko02048	-	-	-	-
CMS1_k127_2109024_38	10181.XP_004864060.1	2.727e-10	63.0	KOG3245@1|root,KOG3245@2759|Eukaryota,3A8BP@33154|Opisthokonta,3BUKS@33208|Metazoa,3DANG@33213|Bilateria,48F9H@7711|Chordata,49D2D@7742|Vertebrata,3JHB8@40674|Mammalia,35QNE@314146|Euarchontoglires,4Q63D@9989|Rodentia	33208|Metazoa	S	Protein of unknown function (DUF1674)	C6orf57	GO:0000104,GO:0000302,GO:0001654,GO:0002376,GO:0003407,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005749,GO:0006091,GO:0006950,GO:0006952,GO:0006955,GO:0006979,GO:0006996,GO:0007005,GO:0007275,GO:0007423,GO:0008150,GO:0008152,GO:0008177,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0016635,GO:0019866,GO:0022607,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0032991,GO:0033108,GO:0033554,GO:0034552,GO:0034553,GO:0034599,GO:0034614,GO:0034622,GO:0042221,GO:0043010,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044237,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045087,GO:0045257,GO:0045273,GO:0045281,GO:0045283,GO:0045333,GO:0048513,GO:0048731,GO:0048856,GO:0050896,GO:0051716,GO:0055114,GO:0060041,GO:0065003,GO:0070469,GO:0070887,GO:0071840,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901700,GO:1901701,GO:1902494,GO:1990204	-	-	-	-	-	-	-	-	-	-	DUF1674
CMS1_k127_2109024_31	1380394.JADL01000008_gene3742	1.005e-38	148.0	COG2009@1|root,COG2009@2|Bacteria,1N02N@1224|Proteobacteria,2UC47@28211|Alphaproteobacteria,2JTDG@204441|Rhodospirillales	204441|Rhodospirillales	C	COG2009 Succinate dehydrogenase fumarate reductase, cytochrome b subunit	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
CMS1_k127_2109024_34	331869.BAL199_10562	2.573e-21	105.0	COG2142@1|root,COG2142@2|Bacteria,1MZND@1224|Proteobacteria,2U94P@28211|Alphaproteobacteria,4BR1M@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	succinate dehydrogenase	sdhD	-	-	ko:K00242	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
CMS1_k127_2109024_0	519989.ECTPHS_11050	1.725e-317	979.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,1RMU2@1236|Gammaproteobacteria,1WW72@135613|Chromatiales	135613|Chromatiales	C	Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
CMS1_k127_2109024_9	519989.ECTPHS_11045	2.134e-130	421.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,1RNWR@1236|Gammaproteobacteria,1WWKQ@135613|Chromatiales	135613|Chromatiales	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_17,Fer4_8
CMS1_k127_2109024_35	349124.Hhal_0042	6.719e-16	79.0	COG2938@1|root,COG2938@2|Bacteria,1N7P4@1224|Proteobacteria,1SCKB@1236|Gammaproteobacteria,1WZ6Q@135613|Chromatiales	135613|Chromatiales	S	Flavinator of succinate dehydrogenase	-	-	-	ko:K09159	-	-	-	-	ko00000,ko02048	-	-	-	Sdh5
CMS1_k127_2109024_27	243233.MCA0240	1.727e-48	186.0	COG0354@1|root,COG0354@2|Bacteria,1N852@1224|Proteobacteria,1RPWB@1236|Gammaproteobacteria,1XEWJ@135618|Methylococcales	135618|Methylococcales	S	Belongs to the GcvT family	-	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
CMS1_k127_2109024_13	713587.THITH_07895	3.408e-116	385.0	COG2957@1|root,COG2957@2|Bacteria,1MX65@1224|Proteobacteria,1RMF1@1236|Gammaproteobacteria,1WXIP@135613|Chromatiales	135613|Chromatiales	E	Belongs to the agmatine deiminase family	aguA	-	-	-	-	-	-	-	-	-	-	-	PAD_porph
CMS1_k127_2109024_10	1123368.AUIS01000006_gene588	3.757e-130	422.0	COG0388@1|root,COG0388@2|Bacteria,1MXG5@1224|Proteobacteria,1RP7S@1236|Gammaproteobacteria,2NCP9@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Carbon-nitrogen hydrolase	-	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
CMS1_k127_2109024_28	497321.C664_09320	4.369e-48	177.0	COG1495@1|root,COG1495@2|Bacteria,1RIJE@1224|Proteobacteria,2VREE@28216|Betaproteobacteria,2KWBD@206389|Rhodocyclales	206389|Rhodocyclales	O	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein	dsbB	-	-	ko:K03611	-	-	-	-	ko00000,ko03110	5.A.2.1	-	-	DsbB
CMS1_k127_2109024_1	1238182.C882_0578	7.108e-288	902.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,2TQJT@28211|Alphaproteobacteria,2JPC0@204441|Rhodospirillales	204441|Rhodospirillales	C	malic enzyme	dme	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,PTA_PTB,malic
CMS1_k127_2109024_7	187272.Mlg_1938	2.486e-181	578.0	COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,1RMU9@1236|Gammaproteobacteria,1WW6N@135613|Chromatiales	135613|Chromatiales	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
CMS1_k127_2109024_25	396588.Tgr7_0843	3.173e-62	224.0	COG4137@1|root,COG4137@2|Bacteria,1R3YD@1224|Proteobacteria,1RPUQ@1236|Gammaproteobacteria,1WX1P@135613|Chromatiales	135613|Chromatiales	S	Cytochrome c assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
CMS1_k127_2109024_8	395493.BegalDRAFT_0572	7.101e-143	466.0	COG4536@1|root,COG4536@2|Bacteria,1NZ99@1224|Proteobacteria,1RNCE@1236|Gammaproteobacteria,45ZZV@72273|Thiotrichales	72273|Thiotrichales	P	PFAM CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
CMS1_k127_2109024_18	1122201.AUAZ01000027_gene2181	2.82e-83	289.0	COG1910@1|root,COG2005@1|root,COG1910@2|Bacteria,COG2005@2|Bacteria,1MVS4@1224|Proteobacteria,1RS4Y@1236|Gammaproteobacteria,4668M@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	COG2005 N-terminal domain of molybdenum-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,HTH_17,PBP_like
CMS1_k127_2109024_14	1000565.METUNv1_01232	3.359e-98	331.0	COG2998@1|root,COG2998@2|Bacteria,1MVSF@1224|Proteobacteria,2VJQG@28216|Betaproteobacteria,2KUXA@206389|Rhodocyclales	206389|Rhodocyclales	H	Bacterial extracellular solute-binding protein	-	-	-	ko:K05772	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	PBP_like_2
CMS1_k127_2109024_16	570967.JMLV01000007_gene910	1.178e-83	285.0	COG1126@1|root,COG1126@2|Bacteria,1MWKQ@1224|Proteobacteria,2TSCU@28211|Alphaproteobacteria,2JRVW@204441|Rhodospirillales	204441|Rhodospirillales	E	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
CMS1_k127_2109024_21	1122135.KB893137_gene1264	9.289e-76	260.0	COG4662@1|root,COG4662@2|Bacteria,1MZVS@1224|Proteobacteria,2TUHN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	ABC-type tungstate transport system, periplasmic component	tupB	-	-	ko:K05773	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	BPD_transp_1
CMS1_k127_2109024_15	1123261.AXDW01000003_gene1832	6.714e-90	314.0	COG3746@1|root,COG3746@2|Bacteria,1RA39@1224|Proteobacteria,1S2UH@1236|Gammaproteobacteria,1X7A7@135614|Xanthomonadales	135614|Xanthomonadales	P	Phosphate-selective porin O and P	-	-	-	ko:K07221	-	-	-	-	ko00000,ko02000	1.B.5.1	-	-	Porin_O_P
CMS1_k127_2109024_37	43989.cce_0003	3.083e-11	65.0	2EH9Q@1|root,33B1J@2|Bacteria,1GAX5@1117|Cyanobacteria,3KIS1@43988|Cyanothece	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2109024_6	713586.KB900536_gene2913	1.076e-186	596.0	COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,1RN2E@1236|Gammaproteobacteria,1WWW0@135613|Chromatiales	135613|Chromatiales	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
CMS1_k127_2109024_12	395493.BegalDRAFT_3161	2.251e-122	402.0	COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,1RM8U@1236|Gammaproteobacteria,45ZWW@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
CMS1_k127_2109024_5	472759.Nhal_3526	1.942e-190	606.0	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,1RPM2@1236|Gammaproteobacteria,1WW1X@135613|Chromatiales	135613|Chromatiales	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	-	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C,Intein_splicing,LAGLIDADG_3
CMS1_k127_2109024_26	1452718.JBOY01000017_gene838	1.304e-52	189.0	COG0359@1|root,COG0359@2|Bacteria,1RD0R@1224|Proteobacteria,1S3WS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
CMS1_k127_2109024_30	323261.Noc_0454	9.611e-40	160.0	2BFY8@1|root,329TX@2|Bacteria,1R582@1224|Proteobacteria,1RY97@1236|Gammaproteobacteria,1WXMV@135613|Chromatiales	135613|Chromatiales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2232
CMS1_k127_2109024_33	396588.Tgr7_0924	6.889e-32	125.0	COG0238@1|root,COG0238@2|Bacteria,1MZ8U@1224|Proteobacteria,1S8R8@1236|Gammaproteobacteria,1WYXU@135613|Chromatiales	135613|Chromatiales	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
CMS1_k127_2109024_29	930169.B5T_00790	7.54e-47	175.0	COG0360@1|root,COG0360@2|Bacteria,1RH82@1224|Proteobacteria,1S5VU@1236|Gammaproteobacteria,1XK6B@135619|Oceanospirillales	135619|Oceanospirillales	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
CMS1_k127_2109024_23	1268237.G114_05425	2.01e-71	249.0	COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,1RN2F@1236|Gammaproteobacteria,1Y3F2@135624|Aeromonadales	135624|Aeromonadales	J	Specifically methylates the ribose of guanosine 2251 in 23S rRNA	rlmB	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
CMS1_k127_2109024_2	765911.Thivi_0516	2.268e-260	822.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,1RMQE@1236|Gammaproteobacteria,1WXF0@135613|Chromatiales	135613|Chromatiales	K	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HTH_12,OB_RNB,RNB,S1
CMS1_k127_2109024_4	713587.THITH_03520	1.21e-210	661.0	COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,1RNEW@1236|Gammaproteobacteria,1WW9J@135613|Chromatiales	135613|Chromatiales	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
CMS1_k127_2109024_11	395493.BegalDRAFT_0859	5.794e-129	424.0	COG3705@1|root,COG3705@2|Bacteria,1MWIG@1224|Proteobacteria,1RPRQ@1236|Gammaproteobacteria,4606C@72273|Thiotrichales	72273|Thiotrichales	E	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine	hisZ	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
CMS1_k127_2109024_36	314285.KT71_01685	1.675e-13	72.0	COG3242@1|root,COG3242@2|Bacteria,1N9FC@1224|Proteobacteria,1SEP6@1236|Gammaproteobacteria,1J79M@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2065)	-	-	-	ko:K09937	-	-	-	-	ko00000	-	-	-	DUF2065
CMS1_k127_2109024_17	1415780.JPOG01000001_gene1810	2.383e-83	286.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,1RM8Z@1236|Gammaproteobacteria,1X3E5@135614|Xanthomonadales	135614|Xanthomonadales	O	HflC and HflK could regulate a protease	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
CMS1_k127_2109024_20	1198232.CYCME_0909	9.681e-78	267.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,1RMUG@1236|Gammaproteobacteria,45ZNE@72273|Thiotrichales	72273|Thiotrichales	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7,HflK_N
CMS1_k127_212728_20	635013.TherJR_1132	8.127e-24	109.0	COG0755@1|root,COG0755@2|Bacteria,1TQZ4@1239|Firmicutes,24BCK@186801|Clostridia,260YW@186807|Peptococcaceae	186801|Clostridia	O	PFAM Cytochrome c assembly protein	ccsA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
CMS1_k127_212728_25	429009.Adeg_2074	8.816e-12	77.0	COG1333@1|root,COG1333@2|Bacteria,1TQ6C@1239|Firmicutes	1239|Firmicutes	O	ResB protein required for cytochrome c	resB	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
CMS1_k127_212728_29	665952.HMPREF1015_00376	0.0006033	49.0	COG0457@1|root,COG0457@2|Bacteria,1V1HX@1239|Firmicutes,4HG5V@91061|Bacilli,1ZCPW@1386|Bacillus	91061|Bacilli	S	COG0457 FOG TPR repeat	yrrB	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_16,TPR_2,TPR_6,TPR_8
CMS1_k127_212728_26	1278309.KB907108_gene1558	3.4e-08	65.0	COG3218@1|root,COG3218@2|Bacteria,1QWQA@1224|Proteobacteria	1224|Proteobacteria	S	Ethylbenzene dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	EB_dh
CMS1_k127_212728_24	443144.GM21_3561	1.978e-14	88.0	COG3209@1|root,COG4932@1|root,COG3209@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K13735,ko:K20276	ko02024,ko05100,map02024,map05100	-	-	-	ko00000,ko00001	-	-	-	Big_2,CarboxypepD_reg,DUF11,DUF3494,SdrD_B
CMS1_k127_212728_21	871968.DESME_09165	2.691e-21	106.0	COG3391@1|root,COG3391@2|Bacteria,1V2KS@1239|Firmicutes,24FSD@186801|Clostridia,263UX@186807|Peptococcaceae	186801|Clostridia	S	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NHL
CMS1_k127_212728_3	511062.GU3_02120	2.3e-203	648.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,1Y3U5@135624|Aeromonadales	135624|Aeromonadales	NU	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	exeE	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
CMS1_k127_212728_7	1255043.TVNIR_1923	7.657e-117	388.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RQ86@1236|Gammaproteobacteria,1WWYV@135613|Chromatiales	135613|Chromatiales	NU	Type II secretion system	-	-	-	ko:K02455	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
CMS1_k127_212728_13	323261.Noc_2893	5.815e-54	193.0	COG4968@1|root,COG4968@2|Bacteria,1QW3U@1224|Proteobacteria,1T2RU@1236|Gammaproteobacteria,1X2NZ@135613|Chromatiales	135613|Chromatiales	U	PFAM type II secretion system protein G	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
CMS1_k127_212728_17	323261.Noc_2892	4.575e-35	140.0	COG4970@1|root,COG4970@2|Bacteria,1NBWI@1224|Proteobacteria,1S5MN@1236|Gammaproteobacteria,1WY85@135613|Chromatiales	135613|Chromatiales	U	General secretion pathway protein H	-	-	-	ko:K02457	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	GspH,N_methyl
CMS1_k127_212728_23	472759.Nhal_0443	2.923e-19	92.0	COG4967@1|root,COG4967@2|Bacteria,1N992@1224|Proteobacteria,1T2RT@1236|Gammaproteobacteria,1WZB5@135613|Chromatiales	135613|Chromatiales	U	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02458	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
CMS1_k127_212728_18	765914.ThisiDRAFT_0497	1.177e-27	123.0	COG4968@1|root,COG4968@2|Bacteria,1NAXM@1224|Proteobacteria	1224|Proteobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02459	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
CMS1_k127_212728_12	472759.Nhal_3652	2.303e-55	206.0	COG3156@1|root,COG3156@2|Bacteria,1RJRE@1224|Proteobacteria,1S6CB@1236|Gammaproteobacteria,1WW8Y@135613|Chromatiales	135613|Chromatiales	U	PFAM General secretion pathway protein K	-	-	-	ko:K02460	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSK
CMS1_k127_212728_16	472759.Nhal_3651	1.098e-40	165.0	COG3166@1|root,COG4972@1|root,COG3166@2|Bacteria,COG4972@2|Bacteria,1RJTG@1224|Proteobacteria,1S6RT@1236|Gammaproteobacteria,1WXKF@135613|Chromatiales	135613|Chromatiales	NU	fimbrial assembly	-	-	-	ko:K02461	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	PilM_2,PilN
CMS1_k127_212728_19	472759.Nhal_3650	2.19e-24	110.0	2DKUH@1|root,30CV1@2|Bacteria,1NCRM@1224|Proteobacteria,1SBMH@1236|Gammaproteobacteria,1X28Z@135613|Chromatiales	135613|Chromatiales	U	Type II secretion system (T2SS), protein M subtype b	-	-	-	ko:K02462	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSM_b
CMS1_k127_212728_28	84531.JMTZ01000021_gene3800	2.88e-05	53.0	2C8JT@1|root,31A2G@2|Bacteria,1RKRE@1224|Proteobacteria,1SI91@1236|Gammaproteobacteria,1X6XN@135614|Xanthomonadales	135614|Xanthomonadales	S	General secretion pathway protein	xpsN	-	-	ko:K02463	ko05111,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	-
CMS1_k127_212728_4	1026882.MAMP_02546	1.707e-177	580.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,1RPJS@1236|Gammaproteobacteria,45ZVF@72273|Thiotrichales	72273|Thiotrichales	NU	Type II and III secretion system protein	-	-	-	-	-	-	-	-	-	-	-	-	Secretin,Secretin_N
CMS1_k127_212728_11	391615.ABSJ01000059_gene2177	6.391e-58	202.0	COG0789@1|root,COG0789@2|Bacteria,1RGYB@1224|Proteobacteria,1S6Y1@1236|Gammaproteobacteria,1J6ER@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional	VL23_01195	-	-	-	-	-	-	-	-	-	-	-	MerR_1
CMS1_k127_212728_15	318161.Sden_1604	3.675e-44	162.0	COG0776@1|root,COG0776@2|Bacteria,1RH5Z@1224|Proteobacteria,1S61Z@1236|Gammaproteobacteria,2QC5B@267890|Shewanellaceae	1236|Gammaproteobacteria	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	himA	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	ko:K04764	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
CMS1_k127_212728_2	1121939.L861_03130	8.2e-220	706.0	COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,1RMIH@1236|Gammaproteobacteria,1XHN9@135619|Oceanospirillales	135619|Oceanospirillales	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
CMS1_k127_212728_6	572477.Alvin_0984	5.401e-145	465.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,1RN22@1236|Gammaproteobacteria,1WXAD@135613|Chromatiales	135613|Chromatiales	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
CMS1_k127_212728_14	472759.Nhal_3205	6.22e-47	172.0	COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,1S3P3@1236|Gammaproteobacteria,1WYQC@135613|Chromatiales	135613|Chromatiales	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
CMS1_k127_212728_22	545276.KB898726_gene1206	3.55e-20	91.0	COG0291@1|root,COG0291@2|Bacteria,1N6V4@1224|Proteobacteria,1SCHI@1236|Gammaproteobacteria,1WZBU@135613|Chromatiales	135613|Chromatiales	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
CMS1_k127_212728_10	472759.Nhal_3207	6.207e-69	237.0	COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,1S4E6@1236|Gammaproteobacteria,1WWSS@135613|Chromatiales	135613|Chromatiales	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
CMS1_k127_212728_1	1286106.MPL1_13068	1.908e-306	951.0	COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,1RMYE@1236|Gammaproteobacteria,45ZTX@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
CMS1_k127_212728_0	1122197.ATWI01000009_gene1790	0.0	1007.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,1RN6Z@1236|Gammaproteobacteria,4645B@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009314,GO:0009380,GO:0009628,GO:0032991,GO:0042802,GO:0044424,GO:0044464,GO:0050896,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
CMS1_k127_212728_5	395493.BegalDRAFT_1205	7.348e-160	512.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,1RNN0@1236|Gammaproteobacteria,45ZUP@72273|Thiotrichales	72273|Thiotrichales	E	Aminotransferase	aspC2	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS1_k127_212728_8	1502770.JQMG01000001_gene1321	3.413e-112	378.0	COG5563@1|root,COG5563@2|Bacteria,1R9G5@1224|Proteobacteria,2VNH0@28216|Betaproteobacteria	28216|Betaproteobacteria	S	HAF family	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter
CMS1_k127_2172801_13	472759.Nhal_0480	2.893e-88	297.0	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,1RNS2@1236|Gammaproteobacteria,1WWQH@135613|Chromatiales	135613|Chromatiales	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	ko:K13283	-	-	-	-	ko00000,ko02000	2.A.4.7.1	-	-	Cation_efflux,ZT_dimer
CMS1_k127_2172801_14	322710.Avin_40140	2.391e-83	281.0	COG3647@1|root,COG3647@2|Bacteria,1N7NB@1224|Proteobacteria,1RS4F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Membrane	yjdF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
CMS1_k127_2172801_21	547045.NEISICOT_03302	4.165e-54	218.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2VM3A@28216|Betaproteobacteria,2KQPW@206351|Neisseriales	206351|Neisseriales	S	Sel1-like repeats.	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
CMS1_k127_2172801_26	1304275.C41B8_12265	7.369e-24	108.0	2EEAU@1|root,33859@2|Bacteria,1NPX9@1224|Proteobacteria,1SJ5Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2172801_15	1116472.MGMO_11c00670	2.137e-80	273.0	COG0625@1|root,COG0625@2|Bacteria,1MWY4@1224|Proteobacteria,1RXVJ@1236|Gammaproteobacteria,1XFNQ@135618|Methylococcales	135618|Methylococcales	O	Glutathione S-transferase, C-terminal domain	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_N_3
CMS1_k127_2172801_17	1068978.AMETH_3328	4.603e-74	259.0	COG2513@1|root,COG2513@2|Bacteria,2GJZZ@201174|Actinobacteria,4E0PY@85010|Pseudonocardiales	201174|Actinobacteria	G	Phosphoenolpyruvate phosphomutase	-	-	4.1.3.32	ko:K20454	ko00760,ko01120,map00760,map01120	-	R01355	RC00286,RC01810	ko00000,ko00001,ko01000	-	-	-	PEP_mutase
CMS1_k127_2172801_32	880073.Calab_1744	2.597e-15	83.0	2ET6W@1|root,33KQY@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2172801_16	1121033.AUCF01000039_gene425	4.286e-78	272.0	COG3391@1|root,COG3391@2|Bacteria,1MXJJ@1224|Proteobacteria,2TTH6@28211|Alphaproteobacteria,2JU8Z@204441|Rhodospirillales	204441|Rhodospirillales	S	TIGRFAM 40-residue YVTN family beta-propeller repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1
CMS1_k127_2172801_23	1304877.KI519399_gene5129	6.178e-43	163.0	COG3832@1|root,COG3832@2|Bacteria,1RD9A@1224|Proteobacteria,2U76G@28211|Alphaproteobacteria,3JT7B@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
CMS1_k127_2172801_31	1177928.TH2_12222	2.371e-15	82.0	COG5455@1|root,COG5455@2|Bacteria,1NGVG@1224|Proteobacteria,2UJS6@28211|Alphaproteobacteria,2JYIV@204441|Rhodospirillales	204441|Rhodospirillales	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2172801_19	62928.azo0042	2.129e-60	217.0	COG5400@1|root,COG5400@2|Bacteria,1RASG@1224|Proteobacteria,2W1ZW@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF1134)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1134
CMS1_k127_2172801_18	472759.Nhal_2733	3.568e-72	256.0	COG2234@1|root,COG2234@2|Bacteria,1MXJC@1224|Proteobacteria,1RQV2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	aminopeptidase	-	-	3.4.11.10	ko:K05994	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PPC,Peptidase_M28
CMS1_k127_2172801_6	1267005.KB911256_gene1670	2.503e-145	471.0	COG1929@1|root,COG1929@2|Bacteria,1MVG9@1224|Proteobacteria,2U21E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Belongs to the glycerate kinase type-1 family	glxK	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
CMS1_k127_2172801_3	349521.HCH_01903	4.176e-166	532.0	COG3977@1|root,COG3977@2|Bacteria,1MVRW@1224|Proteobacteria,1RNK1@1236|Gammaproteobacteria,1XHID@135619|Oceanospirillales	135619|Oceanospirillales	E	catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids	-	-	2.6.1.66	ko:K00835	ko00290,ko01100,ko01110,ko01130,map00290,map01100,map01110,map01130	-	R01215	RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS1_k127_2172801_28	1125863.JAFN01000001_gene2891	1.985e-21	104.0	28IZ5@1|root,33FUK@2|Bacteria,1NKT0@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2172801_35	639282.DEFDS_0849	0.0004168	51.0	COG0664@1|root,COG0664@2|Bacteria,2GG6E@200930|Deferribacteres	200930|Deferribacteres	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
CMS1_k127_2172801_22	631362.Thi970DRAFT_02282	1.194e-46	177.0	COG5473@1|root,COG5473@2|Bacteria,1N9UJ@1224|Proteobacteria,1SZTB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2172801_12	306281.AJLK01000091_gene3531	6.418e-103	338.0	COG0225@1|root,COG0225@2|Bacteria,1G1QF@1117|Cyanobacteria,1JJDA@1189|Stigonemataceae	1117|Cyanobacteria	O	Peptide methionine sulfoxide reductase	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
CMS1_k127_2172801_30	377629.TERTU_1019	1.574e-17	89.0	2E4CH@1|root,32Z7Y@2|Bacteria,1NBRN@1224|Proteobacteria,1SCB9@1236|Gammaproteobacteria,2PPS3@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	S	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
CMS1_k127_2172801_9	1469245.JFBG01000091_gene1645	3.174e-123	402.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,1RN8W@1236|Gammaproteobacteria,1WXNB@135613|Chromatiales	135613|Chromatiales	BQ	PFAM Histone deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
CMS1_k127_2172801_34	1042377.AFPJ01000052_gene1551	7.942e-09	59.0	COG3307@1|root,COG3307@2|Bacteria,1N225@1224|Proteobacteria,1RQWW@1236|Gammaproteobacteria,465GX@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	COG3307 Lipid A core - O-antigen ligase and related enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
CMS1_k127_2172801_11	395493.BegalDRAFT_0499	1.835e-106	359.0	COG3307@1|root,COG3307@2|Bacteria,1RBNE@1224|Proteobacteria,1S2PP@1236|Gammaproteobacteria,46389@72273|Thiotrichales	72273|Thiotrichales	M	O-antigen ligase like membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
CMS1_k127_2172801_4	228410.NE2250	5.282e-161	520.0	COG0662@1|root,COG0836@1|root,COG0662@2|Bacteria,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,2VI4S@28216|Betaproteobacteria,371YG@32003|Nitrosomonadales	28216|Betaproteobacteria	M	TIGRFAM Mannose-1-phosphate guanylyltransferase mannose-6-phosphate isomerase	cpsB	-	2.7.7.13,5.3.1.8	ko:K00971,ko:K16011	ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025	M00114,M00361,M00362	R00885,R01819	RC00002,RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
CMS1_k127_2172801_2	395493.BegalDRAFT_2277	2.092e-166	527.0	COG0451@1|root,COG0451@2|Bacteria,1MXKV@1224|Proteobacteria,1RNJD@1236|Gammaproteobacteria,46189@72273|Thiotrichales	72273|Thiotrichales	GM	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	4.1.1.35	ko:K08678	ko00520,ko01100,map00520,map01100	M00361	R01384	RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
CMS1_k127_2172801_24	765912.Thimo_0978	1.721e-33	132.0	COG1846@1|root,COG1846@2|Bacteria,1N0TY@1224|Proteobacteria,1SADN@1236|Gammaproteobacteria,1WZ4E@135613|Chromatiales	135613|Chromatiales	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
CMS1_k127_2172801_25	2340.JV46_03370	3.266e-31	128.0	COG0250@1|root,COG0250@2|Bacteria,1N01W@1224|Proteobacteria,1S91B@1236|Gammaproteobacteria,1J710@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components	rfaH	GO:0001000,GO:0001073,GO:0001121,GO:0001124,GO:0003674,GO:0003676,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006355,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008494,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031554,GO:0031564,GO:0032268,GO:0032270,GO:0032774,GO:0034248,GO:0034250,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045182,GO:0045727,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090079,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141	-	ko:K05785	-	-	-	-	ko00000,ko03000	-	-	-	NusG
CMS1_k127_2172801_8	1166018.FAES_4962	1.971e-138	446.0	COG1089@1|root,COG1089@2|Bacteria,4NK6P@976|Bacteroidetes,47JY0@768503|Cytophagia	976|Bacteroidetes	M	GDP-mannose 4,6 dehydratase	yefA	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
CMS1_k127_2172801_10	768671.ThimaDRAFT_3491	7.16e-123	401.0	COG1087@1|root,COG1087@2|Bacteria,1MUHI@1224|Proteobacteria,1RMTU@1236|Gammaproteobacteria,1WWNR@135613|Chromatiales	135613|Chromatiales	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	-	-	5.1.3.2,5.1.3.5	ko:K01784,ko:K12448	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R01473,R02984	RC00289,RC00528	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
CMS1_k127_2172801_33	1123242.JH636434_gene4337	2.138e-11	69.0	COG1682@1|root,COG1682@2|Bacteria,2IYXC@203682|Planctomycetes	203682|Planctomycetes	U	COG1682 ABC-type polysaccharide polyol phosphate export systems, permease component	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
CMS1_k127_2172801_7	349161.Dred_1395	1.627e-141	454.0	COG0451@1|root,COG0451@2|Bacteria,1TQV2@1239|Firmicutes,249R2@186801|Clostridia	186801|Clostridia	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
CMS1_k127_2172801_1	398767.Glov_1491	6.438e-186	586.0	COG1089@1|root,COG1089@2|Bacteria,1MUX0@1224|Proteobacteria,42KZY@68525|delta/epsilon subdivisions,2WJ4B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
CMS1_k127_2172801_5	1415780.JPOG01000001_gene1376	2.286e-147	474.0	COG0473@1|root,COG0473@2|Bacteria,1QU2H@1224|Proteobacteria,1T1N6@1236|Gammaproteobacteria,1X358@135614|Xanthomonadales	135614|Xanthomonadales	CE	Catalyzes the formation of 2-oxoglutarate from isocitrate	-	-	1.1.1.41	ko:K00030	ko00020,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010	R00709	RC00114	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
CMS1_k127_2172801_0	1049564.TevJSym_be00270	9.644e-217	693.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,1J57P@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the peptidase S41A family	prc	GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016787,GO:0019538,GO:0023052,GO:0030163,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	BAGE,DUF3340,PDZ,Peptidase_S41
CMS1_k127_2172801_27	1382359.JIAL01000001_gene515	4.255e-22	102.0	COG0457@1|root,COG0457@2|Bacteria,3Y4RD@57723|Acidobacteria,2JJAQ@204432|Acidobacteriia	204432|Acidobacteriia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8
CMS1_k127_2172801_20	395493.BegalDRAFT_2794	1.099e-58	216.0	COG0596@1|root,COG0596@2|Bacteria,1N252@1224|Proteobacteria,1SDH5@1236|Gammaproteobacteria,462GG@72273|Thiotrichales	72273|Thiotrichales	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS1_k127_2172988_0	1123368.AUIS01000003_gene1674	3.517e-125	405.0	COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,1RP7G@1236|Gammaproteobacteria,2NBSY@225057|Acidithiobacillales	225057|Acidithiobacillales	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
CMS1_k127_2172988_1	1408164.MOLA814_00698	4.984e-107	361.0	COG1216@1|root,COG1216@2|Bacteria,1PI1U@1224|Proteobacteria,2VI9D@28216|Betaproteobacteria,1KR4W@119066|unclassified Betaproteobacteria	2|Bacteria	S	overlaps another CDS with the same product name	wbbL_2	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
CMS1_k127_2172988_5	631362.Thi970DRAFT_02856	1.007e-55	212.0	COG0463@1|root,COG0463@2|Bacteria,1NP10@1224|Proteobacteria	1224|Proteobacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2172988_4	391038.Bphy_2292	7.647e-66	234.0	COG1216@1|root,COG1216@2|Bacteria,1RACV@1224|Proteobacteria,2WEK2@28216|Betaproteobacteria,1KHR9@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Pfam Glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
CMS1_k127_2172988_3	292415.Tbd_1873	5.057e-69	246.0	COG0451@1|root,COG0451@2|Bacteria,1MX2J@1224|Proteobacteria,2VJHC@28216|Betaproteobacteria,1KTE1@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
CMS1_k127_2172988_2	314278.NB231_16893	2.383e-70	251.0	COG0472@1|root,COG0472@2|Bacteria,1MWYW@1224|Proteobacteria,1RNAP@1236|Gammaproteobacteria,1WW6T@135613|Chromatiales	135613|Chromatiales	M	PFAM Glycosyl transferase family 4	-	-	-	ko:K13007	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
CMS1_k127_2172988_6	105559.Nwat_2113	9.402e-34	142.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,1RNQ2@1236|Gammaproteobacteria,1WW39@135613|Chromatiales	135613|Chromatiales	GM	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
CMS1_k127_217608_27	1027273.GZ77_22125	6.178e-118	389.0	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,1RMNP@1236|Gammaproteobacteria,1XI4U@135619|Oceanospirillales	135619|Oceanospirillales	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
CMS1_k127_217608_0	243233.MCA3030	0.0	1052.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,1RNB2@1236|Gammaproteobacteria,1XEQA@135618|Methylococcales	135618|Methylococcales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
CMS1_k127_217608_91	1408444.JHYC01000009_gene1686	6.089e-06	53.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,1S64Q@1236|Gammaproteobacteria,1JD90@118969|Legionellales	118969|Legionellales	S	Competence protein	comF	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
CMS1_k127_217608_80	519989.ECTPHS_07421	3.24e-28	122.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,1S64Q@1236|Gammaproteobacteria,1WWVF@135613|Chromatiales	135613|Chromatiales	S	Competence protein	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
CMS1_k127_217608_18	1283300.ATXB01000001_gene1072	7.098e-141	454.0	COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,1RMEQ@1236|Gammaproteobacteria,1XDXY@135618|Methylococcales	135618|Methylococcales	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
CMS1_k127_217608_25	396588.Tgr7_0133	4.743e-123	406.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,1RNS6@1236|Gammaproteobacteria,1WVW0@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	bioF	-	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS1_k127_217608_75	105559.Nwat_0989	1.37e-35	147.0	COG2267@1|root,COG2267@2|Bacteria,1N2R9@1224|Proteobacteria,1T1K8@1236|Gammaproteobacteria,1X2NI@135613|Chromatiales	135613|Chromatiales	I	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters	bioH	-	3.1.1.85	ko:K02170	ko00780,ko01100,map00780,map01100	M00572	R09725	RC00460,RC00461	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS1_k127_217608_49	768671.ThimaDRAFT_3356	5.686e-75	263.0	COG0500@1|root,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,1RY7A@1236|Gammaproteobacteria,1WW45@135613|Chromatiales	135613|Chromatiales	H	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway	bioC	-	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11
CMS1_k127_217608_56	572477.Alvin_0522	1.975e-66	233.0	COG0132@1|root,COG0132@2|Bacteria,1RDRK@1224|Proteobacteria,1RSHS@1236|Gammaproteobacteria,1WXWI@135613|Chromatiales	135613|Chromatiales	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	-	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
CMS1_k127_217608_85	472759.Nhal_0060	6.278e-18	91.0	COG5488@1|root,COG5488@2|Bacteria,1N9B7@1224|Proteobacteria,1SF1J@1236|Gammaproteobacteria,1X1FG@135613|Chromatiales	135613|Chromatiales	S	Integral membrane protein (DUF2244)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2244
CMS1_k127_217608_17	314607.KB13_359	9.208e-142	459.0	COG1622@1|root,COG1622@2|Bacteria,1MWHZ@1224|Proteobacteria,2VH9M@28216|Betaproteobacteria,1KQCB@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	coxB	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrome_CBB3,OmpA
CMS1_k127_217608_1	314607.KB13_1134	8.566e-298	918.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,2VHGU@28216|Betaproteobacteria,1KQBN@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	ctaD	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
CMS1_k127_217608_63	314607.KB13_1014	6.798e-54	197.0	COG3175@1|root,COG3175@2|Bacteria,1RDTU@1224|Proteobacteria,2VHRQ@28216|Betaproteobacteria	28216|Betaproteobacteria	O	cytochrome c oxidase assembly protein CtaG Cox11	ctaG	-	-	ko:K02258	ko00190,ko01100,ko04714,map00190,map01100,map04714	M00154	-	-	ko00000,ko00001,ko00002,ko03029	3.D.4.8	-	-	CtaG_Cox11
CMS1_k127_217608_23	314607.KB13_152	2.131e-125	407.0	COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,2VJAP@28216|Betaproteobacteria,1KQK0@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome c oxidase subunit III	coxC	-	1.9.3.1	ko:K02276,ko:K02299	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX3
CMS1_k127_217608_88	1034943.BN1094_01798	5.711e-14	74.0	2EGIJ@1|root,33AAQ@2|Bacteria,1NH9B@1224|Proteobacteria,1SGKJ@1236|Gammaproteobacteria,1JFAY@118969|Legionellales	118969|Legionellales	S	Protein of unknown function (DUF2909)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2909
CMS1_k127_217608_70	335283.Neut_2391	9.204e-42	166.0	COG3346@1|root,COG3346@2|Bacteria,1MZUH@1224|Proteobacteria,2VSAZ@28216|Betaproteobacteria,372Z1@32003|Nitrosomonadales	28216|Betaproteobacteria	S	SURF1-like protein	surf1	-	-	ko:K14998	-	-	-	-	ko00000,ko03029	3.D.4.8	-	-	SURF1
CMS1_k127_217608_82	1163617.SCD_n02655	1.285e-23	108.0	COG1999@1|root,COG1999@2|Bacteria,1RHK3@1224|Proteobacteria,2VRBY@28216|Betaproteobacteria	28216|Betaproteobacteria	S	signal sequence binding	sco1	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_217608_38	713586.KB900536_gene1812	1.875e-102	342.0	COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,1RQWB@1236|Gammaproteobacteria,1WZSA@135613|Chromatiales	135613|Chromatiales	O	cytochrome oxidase assembly	-	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
CMS1_k127_217608_30	1198232.CYCME_0641	8.073e-114	375.0	COG0109@1|root,COG0109@2|Bacteria,1MW3S@1224|Proteobacteria,1RNHC@1236|Gammaproteobacteria,460H9@72273|Thiotrichales	72273|Thiotrichales	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	cyoE	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
CMS1_k127_217608_77	1122135.KB893170_gene2738	2.189e-34	141.0	2AFPW@1|root,32Z6T@2|Bacteria,1NC9H@1224|Proteobacteria,2UIAS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_217608_71	1454004.AW11_01556	1.54e-40	154.0	2C3ZQ@1|root,32SCF@2|Bacteria,1N27R@1224|Proteobacteria,2VV8G@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM MEKHLA domain protein	-	-	-	-	-	-	-	-	-	-	-	-	MEKHLA
CMS1_k127_217608_47	439235.Dalk_3095	1.971e-81	275.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,42QWV@68525|delta/epsilon subdivisions,2WMPT@28221|Deltaproteobacteria,2MJGI@213118|Desulfobacterales	28221|Deltaproteobacteria	L	DNA-3-methyladenine glycosylase I	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
CMS1_k127_217608_13	1336243.JAEA01000005_gene1304	1.258e-148	475.0	COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,2TR2Q@28211|Alphaproteobacteria,1JQTQ@119045|Methylobacteriaceae	28211|Alphaproteobacteria	V	PFAM ABC transporter	hndI	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0016020,GO:0044464,GO:0050896,GO:0071944	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_217608_22	930169.B5T_04315	1.638e-125	406.0	COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,1RP0Z@1236|Gammaproteobacteria,1XHEP@135619|Oceanospirillales	135619|Oceanospirillales	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
CMS1_k127_217608_76	1232410.KI421424_gene1807	2.96e-35	137.0	2BWVJ@1|root,33YN1@2|Bacteria,1NXTC@1224|Proteobacteria,430BZ@68525|delta/epsilon subdivisions,2WVZK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_217608_74	1026882.MAMP_01473	8.399e-38	143.0	COG1734@1|root,COG1734@2|Bacteria,1MZIB@1224|Proteobacteria,1S8SP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	DnaK suppressor protein	ybiI	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
CMS1_k127_217608_29	1132855.KB913035_gene83	3.226e-114	381.0	COG3213@1|root,COG3213@2|Bacteria,1MUJK@1224|Proteobacteria,2VJ75@28216|Betaproteobacteria,2KNIV@206350|Nitrosomonadales	206350|Nitrosomonadales	P	NnrS protein	-	-	-	ko:K07234	-	-	-	-	ko00000	-	-	-	NnrS
CMS1_k127_217608_52	316067.Geob_2070	5.632e-72	248.0	COG0500@1|root,COG2226@2|Bacteria,1MVIS@1224|Proteobacteria,42VMX@68525|delta/epsilon subdivisions,2WS5W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	2.1.1.17,2.1.1.71	ko:K00570	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00091	R01320,R02056,R03424	RC00003,RC00060,RC00181,RC00496	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11
CMS1_k127_217608_3	1101190.ARWB01000001_gene3611	9.967e-197	631.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TQMV@28211|Alphaproteobacteria,370EF@31993|Methylocystaceae	28211|Alphaproteobacteria	G	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ,PQQ_2,PQQ_3
CMS1_k127_217608_32	472759.Nhal_2201	1.802e-111	366.0	COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,1RMFR@1236|Gammaproteobacteria,1WWRE@135613|Chromatiales	135613|Chromatiales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes	rpoH	-	-	ko:K03089	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r4
CMS1_k127_217608_42	1049564.TevJSym_aa00850	2.092e-88	302.0	COG2177@1|root,COG2177@2|Bacteria,1MU65@1224|Proteobacteria,1RYBV@1236|Gammaproteobacteria,1J4H6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	D	Part of the ABC transporter FtsEX involved in cellular division	ftsX	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0009274,GO:0009276,GO:0009987,GO:0016020,GO:0016021,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032153,GO:0044425,GO:0044464,GO:0051301,GO:0071944	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
CMS1_k127_217608_45	395493.BegalDRAFT_0595	1.162e-84	286.0	COG2884@1|root,COG2884@2|Bacteria,1MVQ4@1224|Proteobacteria,1RMZA@1236|Gammaproteobacteria,4604Q@72273|Thiotrichales	72273|Thiotrichales	D	TIGRFAM Cell division ATP-binding protein FtsE	-	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
CMS1_k127_217608_37	1158150.KB906241_gene961	2.708e-104	349.0	COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,1RNIN@1236|Gammaproteobacteria,1WW5G@135613|Chromatiales	135613|Chromatiales	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
CMS1_k127_217608_9	1049564.TevJSym_aa00880	4.283e-168	540.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,1RN05@1236|Gammaproteobacteria,1JC0J@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Insulinase (Peptidase family M16)	pqqL	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
CMS1_k127_217608_20	472759.Nhal_2204	3.706e-136	447.0	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,1RN3E@1236|Gammaproteobacteria,1WXE8@135613|Chromatiales	135613|Chromatiales	S	PFAM Peptidase M16	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
CMS1_k127_217608_65	519989.ECTPHS_06627	5.716e-49	181.0	COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,1RN21@1236|Gammaproteobacteria,1WY3H@135613|Chromatiales	135613|Chromatiales	L	Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle	-	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
CMS1_k127_217608_61	1163408.UU9_02349	1.908e-57	203.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,1S41J@1236|Gammaproteobacteria,1X5VI@135614|Xanthomonadales	135614|Xanthomonadales	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
CMS1_k127_217608_5	1380387.JADM01000004_gene2906	6.78e-193	618.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,1XIJT@135619|Oceanospirillales	135619|Oceanospirillales	M	gamma-glutamyltransferase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
CMS1_k127_217608_43	472759.Nhal_3599	1.133e-87	296.0	COG0861@1|root,COG0861@2|Bacteria,1MWC9@1224|Proteobacteria,1T1GE@1236|Gammaproteobacteria,1WY65@135613|Chromatiales	135613|Chromatiales	P	PFAM Integral membrane protein TerC	-	-	-	-	-	-	-	-	-	-	-	-	TerC
CMS1_k127_217608_40	396588.Tgr7_0319	3.229e-97	325.0	COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,1RP3J@1236|Gammaproteobacteria,1WX0V@135613|Chromatiales	135613|Chromatiales	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
CMS1_k127_217608_86	1123399.AQVE01000022_gene336	7.753e-18	94.0	2E2KI@1|root,32XPU@2|Bacteria,1RH64@1224|Proteobacteria,1RYC7@1236|Gammaproteobacteria,461G7@72273|Thiotrichales	72273|Thiotrichales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
CMS1_k127_217608_21	243233.MCA3076	2.251e-131	433.0	COG3225@1|root,COG3225@2|Bacteria,1MUXW@1224|Proteobacteria,1RP5U@1236|Gammaproteobacteria,1XEHX@135618|Methylococcales	135618|Methylococcales	N	ABC-type uncharacterized transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
CMS1_k127_217608_57	105559.Nwat_0472	6.956e-64	232.0	COG1277@1|root,COG1277@2|Bacteria,1NZZ9@1224|Proteobacteria,1RP6C@1236|Gammaproteobacteria,1WXUC@135613|Chromatiales	135613|Chromatiales	S	ABC-type transport system involved in multi-copper enzyme maturation, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
CMS1_k127_217608_41	1236959.BAMT01000004_gene900	4.754e-96	325.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,2VJ2B@28216|Betaproteobacteria,2KM5I@206350|Nitrosomonadales	206350|Nitrosomonadales	V	PFAM ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
CMS1_k127_217608_83	1255043.TVNIR_0105	2.468e-23	100.0	COG0267@1|root,COG0267@2|Bacteria,1N6QV@1224|Proteobacteria,1SCEJ@1236|Gammaproteobacteria,1WZA6@135613|Chromatiales	135613|Chromatiales	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
CMS1_k127_217608_78	1122243.KB903773_gene1351	9.319e-33	131.0	COG0227@1|root,COG0227@2|Bacteria,1MZ57@1224|Proteobacteria,1S8UG@1236|Gammaproteobacteria,3NNZ1@468|Moraxellaceae	1236|Gammaproteobacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
CMS1_k127_217608_54	713586.KB900536_gene2333	1.03e-70	245.0	COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,1RP86@1236|Gammaproteobacteria,1WXFP@135613|Chromatiales	135613|Chromatiales	L	Belongs to the UPF0758 family	-	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
CMS1_k127_217608_90	1158760.AQXP01000048_gene1125	2.541e-08	66.0	COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,1RP86@1236|Gammaproteobacteria,1WXFP@135613|Chromatiales	135613|Chromatiales	L	Belongs to the UPF0758 family	-	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
CMS1_k127_217608_14	396588.Tgr7_0102	1.22e-147	477.0	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,1RMKQ@1236|Gammaproteobacteria,1WXCF@135613|Chromatiales	135613|Chromatiales	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	-	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
CMS1_k127_217608_8	697282.Mettu_1833	1.188e-174	580.0	COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,1RMU8@1236|Gammaproteobacteria,1XDTR@135618|Methylococcales	135618|Methylococcales	G	alpha beta alpha domain I	-	-	5.4.2.2,5.4.2.8	ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
CMS1_k127_217608_19	765913.ThidrDRAFT_2119	2.206e-140	451.0	COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,1RNKK@1236|Gammaproteobacteria,1WWCV@135613|Chromatiales	135613|Chromatiales	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
CMS1_k127_217608_58	1121937.AUHJ01000010_gene1592	2.486e-63	223.0	COG1309@1|root,COG1309@2|Bacteria,1MWF7@1224|Proteobacteria,1RPZ6@1236|Gammaproteobacteria,465HE@72275|Alteromonadaceae	1236|Gammaproteobacteria	D	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions	slmA	GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000918,GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0007049,GO:0007346,GO:0008150,GO:0009295,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010564,GO:0010948,GO:0010974,GO:0016043,GO:0019219,GO:0019222,GO:0022402,GO:0022607,GO:0031323,GO:0031326,GO:0031333,GO:0032271,GO:0032272,GO:0032465,GO:0032466,GO:0032506,GO:0032954,GO:0032955,GO:0042802,GO:0043085,GO:0043087,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043254,GO:0043547,GO:0043565,GO:0043590,GO:0044085,GO:0044087,GO:0044093,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0045786,GO:0045930,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051252,GO:0051301,GO:0051302,GO:0051336,GO:0051345,GO:0051726,GO:0051782,GO:0060255,GO:0061640,GO:0065007,GO:0065009,GO:0071840,GO:0080090,GO:0090529,GO:0097159,GO:0140110,GO:1901363,GO:1901891,GO:1901892,GO:1902410,GO:1902412,GO:1902413,GO:1903047,GO:1903436,GO:1903437,GO:1903506,GO:1990837,GO:2000112,GO:2001141	-	ko:K05501	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	TetR_N
CMS1_k127_217608_87	1123257.AUFV01000022_gene27	9.622e-17	89.0	2DNSW@1|root,32YYW@2|Bacteria,1NA4R@1224|Proteobacteria,1SD08@1236|Gammaproteobacteria,1X8PW@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_217608_48	323848.Nmul_A0225	1.35e-80	274.0	COG0461@1|root,COG0461@2|Bacteria,1MW6F@1224|Proteobacteria,2VH9U@28216|Betaproteobacteria,3722I@32003|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
CMS1_k127_217608_28	243233.MCA0321	1.146e-114	375.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,1RN4H@1236|Gammaproteobacteria,1XEVR@135618|Methylococcales	135618|Methylococcales	L	Endonuclease/Exonuclease/phosphatase family	-	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
CMS1_k127_217608_81	713586.KB900536_gene1713	4.121e-24	107.0	2DP15@1|root,3303T@2|Bacteria,1N7NN@1224|Proteobacteria,1S90P@1236|Gammaproteobacteria,1WZKG@135613|Chromatiales	135613|Chromatiales	S	Domain of unknown function (DUF4426)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4426
CMS1_k127_217608_68	472759.Nhal_3795	3.24e-43	164.0	COG0762@1|root,COG0762@2|Bacteria,1RCZV@1224|Proteobacteria,1S6DW@1236|Gammaproteobacteria,1WXC6@135613|Chromatiales	135613|Chromatiales	S	integral membrane protein	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
CMS1_k127_217608_46	349124.Hhal_0946	4.98e-83	284.0	COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,1RNQK@1236|Gammaproteobacteria,1WWVS@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
CMS1_k127_217608_50	1434929.X946_1517	9.482e-73	252.0	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,2VHNY@28216|Betaproteobacteria,1JZTS@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	yggS	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
CMS1_k127_217608_6	391615.ABSJ01000042_gene2252	2.646e-189	594.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,1RN8G@1236|Gammaproteobacteria,1J4KJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	NU	Tfp pilus assembly protein, pilus retraction ATPase PilT	pilT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
CMS1_k127_217608_7	1163617.SCD_n00074	1.261e-185	586.0	COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,2VIWS@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	twitching motility protein	pilU	-	-	ko:K02670	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
CMS1_k127_217608_12	395493.BegalDRAFT_0392	1.328e-151	486.0	COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,1RN0B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	twitching motility protein	uptC	-	-	ko:K02670	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
CMS1_k127_217608_33	1049564.TevJSym_bn00150	2.09e-109	361.0	COG0543@1|root,COG0543@2|Bacteria,1RF43@1224|Proteobacteria,1RQ7W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )	-	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6
CMS1_k127_217608_16	472759.Nhal_0208	6.55e-142	462.0	COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,1T03U@1236|Gammaproteobacteria,1WVVC@135613|Chromatiales	135613|Chromatiales	F	TIGRFAM dihydroorotase, multifunctional complex type	-	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
CMS1_k127_217608_15	472759.Nhal_0209	6.047e-143	460.0	COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,1RPSV@1236|Gammaproteobacteria,1WWU0@135613|Chromatiales	135613|Chromatiales	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
CMS1_k127_217608_59	396588.Tgr7_2912	2.282e-62	220.0	COG2065@1|root,COG2065@2|Bacteria,1RI6U@1224|Proteobacteria,1S6WA@1236|Gammaproteobacteria,1WXPI@135613|Chromatiales	135613|Chromatiales	F	phosphoribosyltransferase	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
CMS1_k127_217608_73	2340.JV46_15770	3.167e-39	151.0	COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,1S96Q@1236|Gammaproteobacteria,1J6MD@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	yqgF	GO:0000966,GO:0000967,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
CMS1_k127_217608_53	395493.BegalDRAFT_3359	8.279e-72	246.0	COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,1S3YV@1236|Gammaproteobacteria,460YI@72273|Thiotrichales	72273|Thiotrichales	K	Belongs to the UPF0301 (AlgH) family	-	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
CMS1_k127_217608_62	1384054.N790_07690	2.155e-57	212.0	COG0810@1|root,COG0810@2|Bacteria,1R330@1224|Proteobacteria,1RQAX@1236|Gammaproteobacteria,1XCS6@135614|Xanthomonadales	135614|Xanthomonadales	M	Periplasmic protein TonB links inner and outer membranes	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
CMS1_k127_217608_26	765912.Thimo_2550	9.651e-119	390.0	COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,1RMU0@1236|Gammaproteobacteria,1WVY1@135613|Chromatiales	135613|Chromatiales	HJ	Belongs to the prokaryotic GSH synthase family	gshB	-	6.3.2.3	ko:K01920	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00497,R10994	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	GSH-S_ATP,GSH-S_N
CMS1_k127_217608_36	511062.GU3_02410	4.976e-105	349.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,1RMQ8@1236|Gammaproteobacteria,1Y42T@135624|Aeromonadales	135624|Aeromonadales	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
CMS1_k127_217608_67	748247.AZKH_0914	2.763e-48	183.0	COG1587@1|root,COG1587@2|Bacteria,1MWZD@1224|Proteobacteria,2VRU9@28216|Betaproteobacteria,2KVD0@206389|Rhodocyclales	206389|Rhodocyclales	H	Uroporphyrinogen-III synthase HemD	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
CMS1_k127_217608_79	1026882.MAMP_00483	2.458e-31	136.0	COG2959@1|root,COG2959@2|Bacteria,1MY3A@1224|Proteobacteria,1RNJY@1236|Gammaproteobacteria,4619H@72273|Thiotrichales	72273|Thiotrichales	H	HemX, putative uroporphyrinogen-III C-methyltransferase	-	-	2.1.1.107	ko:K02496	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03194	RC00003,RC00871	ko00000,ko00001,ko00002,ko01000	-	-	-	HemX
CMS1_k127_217608_66	1415778.JQMM01000001_gene127	1.694e-48	190.0	COG3071@1|root,COG3071@2|Bacteria,1MU7A@1224|Proteobacteria,1RMRG@1236|Gammaproteobacteria,1J5RD@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	enzyme of heme biosynthesis	hemY	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02498	-	-	-	-	ko00000	-	-	-	HemY_N,TPR_2
CMS1_k127_217608_34	497321.C664_17807	2.572e-107	358.0	COG0543@1|root,COG1018@1|root,COG0543@2|Bacteria,COG1018@2|Bacteria,1MV72@1224|Proteobacteria,2VI9K@28216|Betaproteobacteria,2KVA5@206389|Rhodocyclales	206389|Rhodocyclales	C	COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases	ascD	-	1.17.1.1	ko:K00523	ko00520,map00520	-	R03391,R03392	RC00230	ko00000,ko00001,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
CMS1_k127_217608_64	391615.ABSJ01000039_gene1861	1.51e-51	196.0	COG1192@1|root,COG1192@2|Bacteria,1QBJX@1224|Proteobacteria,1S739@1236|Gammaproteobacteria,1J6UB@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	D	AAA domain	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
CMS1_k127_217608_31	314278.NB231_01219	2.683e-113	376.0	COG3954@1|root,COG3954@2|Bacteria,1MWN9@1224|Proteobacteria,1RMS7@1236|Gammaproteobacteria,1WWCG@135613|Chromatiales	135613|Chromatiales	C	PFAM Phosphoribulokinase uridine kinase	-	-	2.7.1.19	ko:K00855	ko00710,ko01100,ko01120,ko01200,map00710,map01100,map01120,map01200	M00165,M00166	R01523	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PRK
CMS1_k127_217608_4	580332.Slit_2679	8.05e-196	627.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2VHAN@28216|Betaproteobacteria,44V3U@713636|Nitrosomonadales	28216|Betaproteobacteria	V	Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation	msbA	-	-	ko:K02021,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS1_k127_217608_11	519989.ECTPHS_05060	1.39e-156	519.0	COG1305@1|root,COG1305@2|Bacteria,1MWCE@1224|Proteobacteria,1RPH9@1236|Gammaproteobacteria,1WXJ3@135613|Chromatiales	135613|Chromatiales	E	PFAM Transglutaminase-like	-	-	2.3.2.13	ko:K22452	-	-	-	-	ko00000,ko01000	-	-	-	DUF3488,DUF4129,Transglut_core
CMS1_k127_217608_55	1163617.SCD_n01286	7.33e-69	249.0	COG1721@1|root,COG1721@2|Bacteria,1R3QD@1224|Proteobacteria,2VN9P@28216|Betaproteobacteria	28216|Betaproteobacteria	S	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CMS1_k127_217608_24	1026882.MAMP_02945	1.464e-124	405.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RP45@1236|Gammaproteobacteria,45ZZF@72273|Thiotrichales	72273|Thiotrichales	S	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS1_k127_217608_51	1449976.KALB_79	1.206e-72	253.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.1.1.222,2.1.1.64	ko:K00568,ko:K15257	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	Methyltransf_23,Methyltransf_31,Methyltransf_9
CMS1_k127_217608_84	391619.PGA1_c18195	6.657e-21	99.0	2EHVD@1|root,33BKY@2|Bacteria,1NAJU@1224|Proteobacteria,2UHP0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_217608_39	317025.Tcr_1907	6.503e-100	331.0	COG0428@1|root,COG0428@2|Bacteria,1N3QA@1224|Proteobacteria,1RR8U@1236|Gammaproteobacteria,460KZ@72273|Thiotrichales	72273|Thiotrichales	P	divalent heavy-metal cations transporter	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	-
CMS1_k127_217608_60	292415.Tbd_1205	3.111e-59	207.0	arCOG05276@1|root,3195F@2|Bacteria,1RHZA@1224|Proteobacteria,2VSYY@28216|Betaproteobacteria,1KTBW@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_217608_72	383372.Rcas_1566	5.297e-40	157.0	2EB79@1|root,3357W@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_217608_10	243233.MCA0383	1.445e-163	526.0	COG0312@1|root,COG0312@2|Bacteria,1MUVW@1224|Proteobacteria,1RPJF@1236|Gammaproteobacteria,1XDTZ@135618|Methylococcales	135618|Methylococcales	S	modulator of DNA gyrase	pmbA	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
CMS1_k127_217608_2	1049564.TevJSym_aq00560	7.006e-281	880.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,1RNJI@1236|Gammaproteobacteria,1J4RW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	DNA helicase	uvrD	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006289,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017116,GO:0022607,GO:0031297,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0042802,GO:0043142,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045005,GO:0046483,GO:0050896,GO:0051259,GO:0051260,GO:0051276,GO:0051716,GO:0065003,GO:0070035,GO:0070581,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
CMS1_k127_217608_69	748280.NH8B_3587	7.436e-43	167.0	COG3245@1|root,COG3245@2|Bacteria,1MZBZ@1224|Proteobacteria,2VMBB@28216|Betaproteobacteria,2KQHK@206351|Neisseriales	206351|Neisseriales	C	cb-type cytochrome c oxidase subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CMS1_k127_217608_35	472759.Nhal_0216	3.927e-107	369.0	COG0729@1|root,COG0729@2|Bacteria,1MUKM@1224|Proteobacteria,1RNQ3@1236|Gammaproteobacteria,1WWT6@135613|Chromatiales	135613|Chromatiales	M	Surface antigen variable number	-	-	-	ko:K07278	-	-	-	-	ko00000,ko02000	1.B.33.2.4	-	-	Bac_surface_Ag,POTRA,POTRA_TamA_1
CMS1_k127_217608_44	323261.Noc_0371	2.315e-86	323.0	COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,1RMMF@1236|Gammaproteobacteria,1WWU1@135613|Chromatiales	135613|Chromatiales	S	TamB, inner membrane protein subunit of TAM complex	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
CMS1_k127_2196765_4	118168.MC7420_5299	1.36e-112	375.0	COG5001@1|root,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,1H7TU@1150|Oscillatoriales	1117|Cyanobacteria	T	COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GAF_2,GGDEF,MHYT,PAS,PAS_3,PAS_9
CMS1_k127_2196765_3	243233.MCA1490	4.827e-131	422.0	COG2171@1|root,COG2171@2|Bacteria,1MU0Y@1224|Proteobacteria,1RPCS@1236|Gammaproteobacteria,1XECK@135618|Methylococcales	135618|Methylococcales	E	Belongs to the transferase hexapeptide repeat family	dapD	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,THDPS_N_2
CMS1_k127_2196765_1	1049564.TevJSym_ad00400	5.844e-171	546.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,1RPGJ@1236|Gammaproteobacteria,1J4YQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	COG0436 Aspartate tyrosine aromatic aminotransferase	dapC	-	2.6.1.17	ko:K14261,ko:K14267	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04475	RC00006	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS1_k127_2196765_2	1121937.AUHJ01000005_gene2197	7.459e-146	470.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,1RMZQ@1236|Gammaproteobacteria,465TC@72275|Alteromonadaceae	1236|Gammaproteobacteria	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0000287,GO:0003674,GO:0003824,GO:0003862,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030145,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034198,GO:0042594,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0071496,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1990928	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iECs_1301.ECs0077,iYL1228.KPN_00079,iZ_1308.Z0082	Iso_dh
CMS1_k127_2196765_0	396588.Tgr7_1248	4.88e-175	554.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,1RNB6@1236|Gammaproteobacteria,1WWMZ@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
CMS1_k127_2196765_9	396588.Tgr7_1249	2.008e-14	79.0	COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,1RMM5@1236|Gammaproteobacteria,1WVVA@135613|Chromatiales	135613|Chromatiales	NU	FimV C-terminal	-	-	-	ko:K08086	-	-	-	-	ko00000	-	-	-	TPR_19
CMS1_k127_2196765_7	1117647.M5M_00585	5.27e-72	276.0	COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,1RMM5@1236|Gammaproteobacteria,1J4F9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	NU	COG3170 Tfp pilus assembly protein FimV	fimV	-	-	ko:K08086	-	-	-	-	ko00000	-	-	-	LysM,TPR_19
CMS1_k127_2196765_5	1049564.TevJSym_ar00110	6.137e-96	321.0	COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,1RMK2@1236|Gammaproteobacteria,1J4NT@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0000049,GO:0001522,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
CMS1_k127_2196765_6	1179778.PMM47T1_27910	2.526e-75	259.0	COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,1S41P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
CMS1_k127_2196765_8	395493.BegalDRAFT_1051	4.117e-71	243.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,1RP4D@1236|Gammaproteobacteria,4601W@72273|Thiotrichales	72273|Thiotrichales	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS1_k127_2216975_2	765912.Thimo_2101	6.42e-223	715.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,1RNHV@1236|Gammaproteobacteria,1WXN2@135613|Chromatiales	135613|Chromatiales	M	Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)	-	-	2.4.1.129,3.4.16.4	ko:K05365	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase,UB2H
CMS1_k127_2216975_28	1232410.KI421426_gene1441	3.672e-21	100.0	COG3063@1|root,COG3063@2|Bacteria,1QZ5S@1224|Proteobacteria,42XK8@68525|delta/epsilon subdivisions,2WSKB@28221|Deltaproteobacteria,43V3K@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2216975_18	243233.MCA0071	7.928e-50	183.0	COG2078@1|root,COG2078@2|Bacteria,1RJP4@1224|Proteobacteria,1S6FG@1236|Gammaproteobacteria,1XF04@135618|Methylococcales	135618|Methylococcales	S	pfam ammecr1	-	-	-	-	-	-	-	-	-	-	-	-	AMMECR1
CMS1_k127_2216975_15	765912.Thimo_3050	3.676e-100	333.0	COG1355@1|root,COG1355@2|Bacteria,1MXK5@1224|Proteobacteria,1RQPK@1236|Gammaproteobacteria,1WX63@135613|Chromatiales	135613|Chromatiales	S	Belongs to the MEMO1 family	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
CMS1_k127_2216975_7	472759.Nhal_3602	1.981e-190	600.0	COG1180@1|root,COG1180@2|Bacteria,1R8XY@1224|Proteobacteria,1T0C7@1236|Gammaproteobacteria,1X2MB@135613|Chromatiales	135613|Chromatiales	O	Radical SAM superfamily	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
CMS1_k127_2216975_31	1229780.BN381_130143	5.854e-08	55.0	2DREZ@1|root,33BFB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2216975_21	203122.Sde_2710	1.194e-42	160.0	COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,1S3Y7@1236|Gammaproteobacteria,4677T@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Required for maturation of 30S ribosomal subunits	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
CMS1_k127_2216975_5	713586.KB900536_gene3059	2.122e-214	676.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,1RNQS@1236|Gammaproteobacteria,1WVXP@135613|Chromatiales	135613|Chromatiales	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
CMS1_k127_2216975_1	323261.Noc_2120	1.244e-286	902.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,1RM9X@1236|Gammaproteobacteria,1WVXH@135613|Chromatiales	135613|Chromatiales	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N,IF2_assoc
CMS1_k127_2216975_27	395493.BegalDRAFT_3106	4.192e-23	102.0	COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,1S9AF@1236|Gammaproteobacteria,46168@72273|Thiotrichales	72273|Thiotrichales	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
CMS1_k127_2216975_13	396588.Tgr7_1005	3.98e-103	344.0	COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,1RMKP@1236|Gammaproteobacteria,1WVXW@135613|Chromatiales	135613|Chromatiales	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C_2,TruB_N
CMS1_k127_2216975_24	323848.Nmul_A2554	3.241e-31	125.0	COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,2VU1D@28216|Betaproteobacteria,373G3@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
CMS1_k127_2216975_0	754476.Q7A_1301	3.459e-312	969.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,1RNBF@1236|Gammaproteobacteria,4601N@72273|Thiotrichales	72273|Thiotrichales	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
CMS1_k127_2216975_6	395965.Msil_2867	5.121e-200	641.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TQMV@28211|Alphaproteobacteria,3NCZP@45404|Beijerinckiaceae	28211|Alphaproteobacteria	G	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ,PQQ_2,PQQ_3
CMS1_k127_2216975_14	358220.C380_05155	1.085e-100	342.0	COG2114@1|root,COG2114@2|Bacteria,1MV1V@1224|Proteobacteria,2VJ72@28216|Betaproteobacteria,4ABWU@80864|Comamonadaceae	28216|Betaproteobacteria	T	Adenylate cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc,HAMP
CMS1_k127_2216975_26	1504822.CCNO01000015_gene1005	1.583e-26	116.0	COG0212@1|root,COG0212@2|Bacteria,2NRKD@2323|unclassified Bacteria	2|Bacteria	H	5-formyltetrahydrofolate cyclo-ligase family	ygfA	GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	iECABU_c1320.ECABU_c31940,iECOK1_1307.ECOK1_3298,iECSF_1327.ECSF_2705,iUTI89_1310.UTI89_C3298	5-FTHF_cyc-lig
CMS1_k127_2216975_25	203122.Sde_1203	1.484e-30	121.0	COG0228@1|root,COG0228@2|Bacteria,1MZCT@1224|Proteobacteria,1S8RT@1236|Gammaproteobacteria,467U2@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
CMS1_k127_2216975_20	472759.Nhal_0926	1.092e-42	162.0	COG0806@1|root,COG0806@2|Bacteria,1MWQR@1224|Proteobacteria,1RNJ2@1236|Gammaproteobacteria,1WY0M@135613|Chromatiales	135613|Chromatiales	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
CMS1_k127_2216975_12	29486.NJ56_04095	4.848e-107	354.0	COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,1RMWC@1236|Gammaproteobacteria,41F0C@629|Yersinia	1236|Gammaproteobacteria	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
CMS1_k127_2216975_19	2340.JV46_04210	2.01e-49	179.0	COG0335@1|root,COG0335@2|Bacteria,1RH3A@1224|Proteobacteria,1S5XX@1236|Gammaproteobacteria,1J65P@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
CMS1_k127_2216975_23	267608.RSc2543	2.91e-31	129.0	COG0350@1|root,COG0350@2|Bacteria,1RGB5@1224|Proteobacteria,2VRHP@28216|Betaproteobacteria,1KFU1@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Methylated-DNA- protein -cysteine S-methyltransferase	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1
CMS1_k127_2216975_11	472759.Nhal_0930	3.59e-109	364.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,1RPI8@1236|Gammaproteobacteria,1WW40@135613|Chromatiales	135613|Chromatiales	L	TIGRFAM Tyrosine recombinase XerD	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
CMS1_k127_2216975_30	1318628.MARLIPOL_18045	4.353e-11	69.0	2DR2Y@1|root,339YA@2|Bacteria,1NHB7@1224|Proteobacteria,1SH0X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4124)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124
CMS1_k127_2216975_4	1163617.SCD_n00030	1.65e-216	688.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	type II secretion system protein E	gspE1	-	-	ko:K02454,ko:K02652,ko:K12276	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
CMS1_k127_2216975_16	1026882.MAMP_03062	1.228e-62	223.0	COG1651@1|root,COG1651@2|Bacteria,1RD39@1224|Proteobacteria,1S3U8@1236|Gammaproteobacteria,460JH@72273|Thiotrichales	72273|Thiotrichales	O	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process	-	-	5.3.4.1	ko:K03981	-	-	-	-	ko00000,ko01000,ko02044,ko03110	3.A.7.11.1	-	-	DsbC_N,Thioredoxin_2
CMS1_k127_2216975_22	395493.BegalDRAFT_2163	3.263e-35	143.0	2DNRW@1|root,32YUN@2|Bacteria,1NEJX@1224|Proteobacteria,1T4C1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
CMS1_k127_2216975_8	1121939.L861_12905	5.338e-159	515.0	COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,1RMAJ@1236|Gammaproteobacteria,1XHK9@135619|Oceanospirillales	135619|Oceanospirillales	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	hldE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
CMS1_k127_2216975_10	338963.Pcar_0024	8.301e-116	383.0	COG0451@1|root,COG0451@2|Bacteria,1MVE4@1224|Proteobacteria,42MC1@68525|delta/epsilon subdivisions,2WJ24@28221|Deltaproteobacteria,43UKS@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose	hldD	-	5.1.3.20	ko:K03274	ko00540,ko01100,map00540,map01100	M00064	R05176	RC01291	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase
CMS1_k127_2216975_9	1163407.UU7_06563	1.054e-118	396.0	COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,1RNBR@1236|Gammaproteobacteria,1X4GI@135614|Xanthomonadales	135614|Xanthomonadales	M	transferase	waaA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_1,Glycos_transf_N
CMS1_k127_2216975_29	857087.Metme_1751	1.532e-13	76.0	2C7YM@1|root,32RK3@2|Bacteria,1N2IQ@1224|Proteobacteria,1SDXB@1236|Gammaproteobacteria,1XFBF@135618|Methylococcales	135618|Methylococcales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2216975_17	1116472.MGMO_105c00620	5.361e-61	220.0	COG5501@1|root,COG5501@2|Bacteria,1PB0I@1224|Proteobacteria,1S435@1236|Gammaproteobacteria,1XDZ1@135618|Methylococcales	135618|Methylococcales	S	PFAM Sulphur oxidation protein SoxZ	-	-	-	ko:K17226	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	SoxY,SoxZ
CMS1_k127_2216975_3	1469245.JFBG01000046_gene2257	7.229e-220	695.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,1RN5D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Dehydrogenase	xoxF	-	1.1.2.8	ko:K00114	ko00010,ko00625,ko01100,ko01110,ko01120,ko01130,map00010,map00625,map01100,map01110,map01120,map01130	-	R05062,R05198,R05285	RC00087,RC00088,RC01039	ko00000,ko00001,ko01000	-	-	-	PQQ
CMS1_k127_2241446_1	1267005.KB911255_gene2710	4.217e-06	51.0	COG0631@1|root,COG0631@2|Bacteria,1MVE7@1224|Proteobacteria,2U6K4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	COG0631 Serine threonine protein phosphatase	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
CMS1_k127_2241446_0	472759.Nhal_1290	5.972e-255	803.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RMU1@1236|Gammaproteobacteria,1WWGW@135613|Chromatiales	135613|Chromatiales	L	TIGRFAM ATP-dependent helicase HrpA	-	-	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
CMS1_k127_2350629_2	713586.KB900536_gene3089	7.101e-236	736.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,1RMT8@1236|Gammaproteobacteria,1WXCW@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
CMS1_k127_2350629_1	713586.KB900536_gene3090	2.741e-264	822.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,1RP81@1236|Gammaproteobacteria,1WVVJ@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
CMS1_k127_2350629_5	598467.BrE312_1127	1.674e-53	193.0	COG0590@1|root,COG0590@2|Bacteria,1RGU0@1224|Proteobacteria,1S60Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	GO:0002097,GO:0002100,GO:0003674,GO:0003824,GO:0004000,GO:0005488,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008251,GO:0008270,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0052717,GO:0071704,GO:0090304,GO:1901360	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam,dCMP_cyt_deam_1
CMS1_k127_2350629_6	264198.Reut_A2850	2.755e-48	179.0	COG1546@1|root,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,2VSQF@28216|Betaproteobacteria,1K1WW@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA
CMS1_k127_2350629_7	472759.Nhal_1117	3.291e-33	134.0	COG1514@1|root,COG1514@2|Bacteria,1RDB2@1224|Proteobacteria,1SCZX@1236|Gammaproteobacteria,1WZ3C@135613|Chromatiales	135613|Chromatiales	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
CMS1_k127_2350629_3	1286106.MPL1_07318	1.165e-171	545.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,1RMHP@1236|Gammaproteobacteria,45ZTK@72273|Thiotrichales	72273|Thiotrichales	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
CMS1_k127_2350629_8	472759.Nhal_1119	8.277e-32	130.0	COG2137@1|root,COG2137@2|Bacteria,1N6P6@1224|Proteobacteria,1SCMF@1236|Gammaproteobacteria,1WYJU@135613|Chromatiales	135613|Chromatiales	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
CMS1_k127_2350629_0	713586.KB900536_gene28	0.0	1140.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,1RMWZ@1236|Gammaproteobacteria,1WXPB@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
CMS1_k127_2350629_4	519989.ECTPHS_12438	5.607e-97	320.0	COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,1RN1G@1236|Gammaproteobacteria,1WW7C@135613|Chromatiales	135613|Chromatiales	E	Belongs to the aspartokinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
CMS1_k127_2473877_14	243233.MCA0011	4.902e-17	80.0	COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,1RNWJ@1236|Gammaproteobacteria,1XEK1@135618|Methylococcales	135618|Methylococcales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
CMS1_k127_2473877_0	105559.Nwat_3129	2.993e-254	789.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,1RN6U@1236|Gammaproteobacteria,1WW2C@135613|Chromatiales	135613|Chromatiales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
CMS1_k127_2473877_9	323261.Noc_3073	5.787e-53	190.0	COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,1S25H@1236|Gammaproteobacteria,1WY0Q@135613|Chromatiales	135613|Chromatiales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
CMS1_k127_2473877_2	323261.Noc_3072	1.274e-157	510.0	COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,1RNKE@1236|Gammaproteobacteria,1WWG8@135613|Chromatiales	135613|Chromatiales	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3
CMS1_k127_2473877_4	247490.KSU1_C1165	1.902e-76	264.0	COG0388@1|root,COG0388@2|Bacteria,2IXKW@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.1.6	ko:K01431	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R00905,R04666,R08228	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase
CMS1_k127_2473877_8	1123367.C666_06140	1.148e-55	199.0	COG0684@1|root,COG0684@2|Bacteria,1RH18@1224|Proteobacteria,2VR2C@28216|Betaproteobacteria,2KW8N@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions	-	-	-	ko:K02553	-	-	-	-	ko00000,ko03019	-	-	-	RraA-like
CMS1_k127_2473877_11	1282876.BAOK01000001_gene1618	1.383e-41	158.0	COG4520@1|root,COG4520@2|Bacteria,1N0YF@1224|Proteobacteria,2UA8D@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	surface antigen	omp	-	-	-	-	-	-	-	-	-	-	-	17kDa_Anti_2,Gly-zipper_Omp,Rick_17kDa_Anti
CMS1_k127_2473877_13	243365.CV_3305	3.824e-18	94.0	COG3471@1|root,COG3471@2|Bacteria,1MZA2@1224|Proteobacteria,2VQW2@28216|Betaproteobacteria,2KTZU@206351|Neisseriales	206351|Neisseriales	S	Protein of unknown function (DUF541)	-	-	-	-	-	-	-	-	-	-	-	-	SIMPL
CMS1_k127_2473877_1	391615.ABSJ01000041_gene63	6.362e-188	595.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,1RM7N@1236|Gammaproteobacteria,1J53B@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Aminotransferase	hemL	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016853,GO:0016866,GO:0016869,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042286,GO:0042440,GO:0042802,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iUMNK88_1353.UMNK88_158	Aminotran_3
CMS1_k127_2473877_10	1122185.N792_02895	2.042e-49	183.0	COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,1S6QS@1236|Gammaproteobacteria,1X6BT@135614|Xanthomonadales	135614|Xanthomonadales	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
CMS1_k127_2473877_6	1123400.KB904769_gene2862	6.399e-64	228.0	COG0351@1|root,COG0351@2|Bacteria,1MU9J@1224|Proteobacteria,1RNFP@1236|Gammaproteobacteria,460IZ@72273|Thiotrichales	72273|Thiotrichales	H	Phosphomethylpyrimidine kinase	-	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
CMS1_k127_2473877_7	1288494.EBAPG3_18720	3.612e-59	208.0	COG1981@1|root,COG1981@2|Bacteria,1RHGS@1224|Proteobacteria,2VR5Y@28216|Betaproteobacteria,3737C@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Uncharacterised protein family (UPF0093)	-	-	-	ko:K08973	-	-	-	-	ko00000	-	-	-	UPF0093
CMS1_k127_2473877_12	697282.Mettu_4334	4.123e-40	156.0	COG0526@1|root,COG0526@2|Bacteria,1RDGI@1224|Proteobacteria,1S8ZA@1236|Gammaproteobacteria,1XFDF@135618|Methylococcales	135618|Methylococcales	O	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS1_k127_2473877_3	1286106.MPL1_00517	2.525e-85	287.0	28JRZ@1|root,2Z9HI@2|Bacteria,1R52Z@1224|Proteobacteria,1RRWN@1236|Gammaproteobacteria,4623B@72273|Thiotrichales	72273|Thiotrichales	S	Domain of unknown function (DUF4126)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4126
CMS1_k127_2473877_5	572477.Alvin_0109	4.95e-74	255.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,1RNMX@1236|Gammaproteobacteria,1WWVX@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
CMS1_k127_2610631_3	1297863.APJF01000030_gene983	7.11e-14	75.0	COG1835@1|root,COG1835@2|Bacteria,1N45H@1224|Proteobacteria,2UGVA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
CMS1_k127_2610631_1	1122247.C731_4141	7.641e-202	638.0	COG0493@1|root,COG0493@2|Bacteria,2GJ0A@201174|Actinobacteria,232J4@1762|Mycobacteriaceae	201174|Actinobacteria	C	glutamate synthase	gltD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	iNJ661.Rv3858c	Fer4_20,Pyr_redox_2
CMS1_k127_2610631_0	671143.DAMO_0867	0.0	2348.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,2NP08@2323|unclassified Bacteria	2|Bacteria	E	Glutamate synthase central domain	gltB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016020,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
CMS1_k127_2610631_2	713586.KB900536_gene2820	2.148e-86	293.0	COG0644@1|root,COG0644@2|Bacteria,1MXQY@1224|Proteobacteria,1SEJ8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	geranylgeranyl reductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
CMS1_k127_2693670_11	653045.Strvi_5071	4.78e-10	66.0	COG0421@1|root,COG0421@2|Bacteria	2|Bacteria	E	spermidine synthase activity	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
CMS1_k127_2693670_10	181119.XP_005528667.1	1.576e-29	136.0	28K3T@1|root,2QSIA@2759|Eukaryota,3974K@33154|Opisthokonta,3BBX0@33208|Metazoa,3CV1I@33213|Bilateria,485N6@7711|Chordata,4962A@7742|Vertebrata,4GM0F@8782|Aves	33208|Metazoa	S	Transmembrane protein 260	TMEM260	-	-	-	-	-	-	-	-	-	-	-	DUF2723
CMS1_k127_2693670_4	1380394.JADL01000001_gene2802	8.194e-133	432.0	COG1216@1|root,COG2246@1|root,COG1216@2|Bacteria,COG2246@2|Bacteria,1MV8J@1224|Proteobacteria,2TTYF@28211|Alphaproteobacteria,2JUZ4@204441|Rhodospirillales	204441|Rhodospirillales	M	GtrA-like protein	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2,GtrA
CMS1_k127_2693670_2	1117647.M5M_08620	4.868e-155	500.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1J4G2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	pilR	-	-	ko:K02481,ko:K02667	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS1_k127_2693670_6	395493.BegalDRAFT_1870	1.587e-121	408.0	COG0642@1|root,COG2205@2|Bacteria,1MXF8@1224|Proteobacteria,1RMMI@1236|Gammaproteobacteria,45ZTT@72273|Thiotrichales	72273|Thiotrichales	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	2.7.13.3	ko:K02668	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA
CMS1_k127_2693670_3	395493.BegalDRAFT_1221	2.563e-143	466.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,1RMSU@1236|Gammaproteobacteria,45ZUM@72273|Thiotrichales	72273|Thiotrichales	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
CMS1_k127_2693670_5	1234364.AMSF01000024_gene3789	9.493e-131	422.0	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,1RM7Y@1236|Gammaproteobacteria,1X36R@135614|Xanthomonadales	135614|Xanthomonadales	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
CMS1_k127_2693670_0	519989.ECTPHS_01999	1.903e-195	623.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,1RNKA@1236|Gammaproteobacteria,1WWS1@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
CMS1_k127_2693670_8	754476.Q7A_1355	5.293e-98	326.0	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,1RSE6@1236|Gammaproteobacteria,460GM@72273|Thiotrichales	72273|Thiotrichales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
CMS1_k127_2693670_7	227377.CBU_0757	1.734e-103	347.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,1RN7F@1236|Gammaproteobacteria,1JCRC@118969|Legionellales	118969|Legionellales	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
CMS1_k127_2693670_9	754476.Q7A_2453	1.139e-70	247.0	COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,1RNV4@1236|Gammaproteobacteria,460JQ@72273|Thiotrichales	72273|Thiotrichales	S	Belongs to the multicopper oxidase YfiH RL5 family	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
CMS1_k127_2693670_1	1049564.TevJSym_ai00340	1.629e-173	550.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,1RN55@1236|Gammaproteobacteria,1J534@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0031249,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0050896,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
CMS1_k127_2715414_1	765912.Thimo_1406	7.781e-49	179.0	COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,1S9G0@1236|Gammaproteobacteria,1WYDP@135613|Chromatiales	135613|Chromatiales	K	Ribosomal-protein-alanine acetyltransferase	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
CMS1_k127_2715414_0	243233.MCA2276	2.208e-81	276.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,1S2U7@1236|Gammaproteobacteria,1XF2F@135618|Methylococcales	135618|Methylococcales	L	Phage SPO1 DNA polymerase-related protein	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
CMS1_k127_2715414_2	243233.MCA2275	4.457e-08	54.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,1RMWE@1236|Gammaproteobacteria,1XDJV@135618|Methylococcales	135618|Methylococcales	H	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
CMS1_k127_2717939_8	765911.Thivi_0979	4.094e-177	567.0	COG3243@1|root,COG3243@2|Bacteria,1MUNE@1224|Proteobacteria,1RNZI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Protein of unknown function (DUF3141)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3141
CMS1_k127_2717939_9	1209072.ALBT01000011_gene3172	1.417e-163	521.0	COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,1RP9Z@1236|Gammaproteobacteria,1FFRX@10|Cellvibrio	1236|Gammaproteobacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
CMS1_k127_2717939_7	519989.ECTPHS_03642	1.312e-196	629.0	COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,1RMF4@1236|Gammaproteobacteria,1WW9D@135613|Chromatiales	135613|Chromatiales	L	single-stranded-DNA-specific exonuclease RecJ	-	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
CMS1_k127_2717939_10	396595.TK90_1037	2.321e-135	435.0	COG1305@1|root,COG1305@2|Bacteria,1MWAI@1224|Proteobacteria,1RRMA@1236|Gammaproteobacteria,1WWEH@135613|Chromatiales	135613|Chromatiales	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,Transglut_core
CMS1_k127_2717939_15	1049564.TevJSym_ba00250	1.731e-44	175.0	COG4255@1|root,COG4255@2|Bacteria,1RA9X@1224|Proteobacteria,1S23W@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	rpfE	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2717939_6	396588.Tgr7_1440	4.643e-205	642.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,1TJ1K@1236|Gammaproteobacteria,1WXNM@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS1_k127_2717939_5	1049564.TevJSym_ba00270	3.958e-208	655.0	COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,1RPEU@1236|Gammaproteobacteria,1J4Q9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	homoserine dehydrogenase	hom	-	1.1.1.3,2.7.2.4	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
CMS1_k127_2717939_4	396588.Tgr7_1438	1.01e-210	660.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,1RQBM@1236|Gammaproteobacteria,1WWV0@135613|Chromatiales	135613|Chromatiales	E	aminotransferase class I and II	-	-	-	ko:K14261	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS1_k127_2717939_12	243233.MCA0381	7.586e-94	316.0	COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,1RNVZ@1236|Gammaproteobacteria,1XEP3@135618|Methylococcales	135618|Methylococcales	S	Carbon-nitrogen hydrolase	-	-	-	ko:K11206	-	-	-	-	ko00000,ko01000	-	-	-	CN_hydrolase
CMS1_k127_2717939_3	314278.NB231_05811	2.548e-217	684.0	COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,1RMA5@1236|Gammaproteobacteria,1WWCQ@135613|Chromatiales	135613|Chromatiales	S	modulator of DNA gyrase	tldD	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
CMS1_k127_2717939_23	1206733.BAGC01000050_gene2621	1.42e-10	68.0	2ECK6@1|root,336IB@2|Bacteria,2HUFN@201174|Actinobacteria,4G5H6@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2717939_21	1224318.DT73_12110	2.443e-16	83.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NT	chemotaxis, protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,dCache_1
CMS1_k127_2717939_14	323261.Noc_0901	1.252e-58	213.0	COG3063@1|root,COG3063@2|Bacteria,1MXPC@1224|Proteobacteria,1RY78@1236|Gammaproteobacteria,1WWUQ@135613|Chromatiales	135613|Chromatiales	NU	TIGRFAM type IV pilus biogenesis stability protein PilW	-	-	-	ko:K02656	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	LysM,TPR_10,TPR_14,TPR_16,TPR_17,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
CMS1_k127_2717939_13	192952.MM_2797	8.184e-67	234.0	COG1741@1|root,arCOG02935@2157|Archaea,2XTZ7@28890|Euryarchaeota	28890|Euryarchaeota	S	Belongs to the Pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
CMS1_k127_2717939_11	472759.Nhal_3098	5.274e-106	357.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,1RMKV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Amino Acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
CMS1_k127_2717939_1	1452718.JBOY01000135_gene1460	7.876e-245	766.0	COG0459@1|root,COG0459@2|Bacteria,1PMNK@1224|Proteobacteria,1S07M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	-	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
CMS1_k127_2717939_20	1454004.AW11_02883	3.024e-19	93.0	2BW01@1|root,32RUH@2|Bacteria,1N665@1224|Proteobacteria,2VVCA@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2717939_19	1255043.TVNIR_3720	1.77e-31	128.0	COG0590@1|root,COG0590@2|Bacteria,1R1KN@1224|Proteobacteria	1224|Proteobacteria	FJ	Protein of unknown function (DUF3175)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3175
CMS1_k127_2717939_16	1298867.AUES01000016_gene3928	6.934e-43	161.0	COG1073@1|root,COG1765@1|root,COG1073@2|Bacteria,COG1765@2|Bacteria,1N2BT@1224|Proteobacteria,2TQN7@28211|Alphaproteobacteria,3JQSS@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	OsmC-like protein	MA20_16590	-	-	ko:K06889,ko:K07397	-	-	-	-	ko00000	-	-	-	Hydrolase_4,OsmC
CMS1_k127_2717939_2	1123256.KB907927_gene1701	1.071e-222	705.0	COG1387@1|root,COG1387@2|Bacteria,1MYXV@1224|Proteobacteria,1RXT9@1236|Gammaproteobacteria,1X4PW@135614|Xanthomonadales	135614|Xanthomonadales	L	DNA polymerase beta thumb	-	-	-	-	-	-	-	-	-	-	-	-	DNA_pol_B_thumb,HHH_5,HHH_8,PHP
CMS1_k127_2717939_18	105559.Nwat_0698	2.577e-33	132.0	COG1544@1|root,COG1544@2|Bacteria,1RJ55@1224|Proteobacteria,1S5AA@1236|Gammaproteobacteria,1X0WB@135613|Chromatiales	135613|Chromatiales	J	PFAM Cold-shock protein, DNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	CSD,Ribosomal_S30AE
CMS1_k127_2717939_22	472759.Nhal_1640	8.764e-11	71.0	COG0642@1|root,COG2205@2|Bacteria,1QXWZ@1224|Proteobacteria,1T4I3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2717939_0	396588.Tgr7_0259	1.533e-289	910.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,1RMPC@1236|Gammaproteobacteria,1WXPW@135613|Chromatiales	135613|Chromatiales	O	Belongs to the peptidase S16 family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_32,Lon_C
CMS1_k127_2717939_17	243233.MCA0583	1.707e-39	151.0	COG0517@1|root,COG0517@2|Bacteria,1QJRF@1224|Proteobacteria,1THSQ@1236|Gammaproteobacteria,1XFJQ@135618|Methylococcales	135618|Methylococcales	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
CMS1_k127_2720434_17	765914.ThisiDRAFT_1406	5.483e-53	200.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,EAL,GAF_2,GGDEF,PAS_9
CMS1_k127_2720434_19	1038869.AXAN01000014_gene3313	1.259e-49	194.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2VMMZ@28216|Betaproteobacteria,1JZWZ@119060|Burkholderiaceae	28216|Betaproteobacteria	T	response regulator	wspR	-	2.7.7.65	ko:K11444	ko02020,ko02025,map02020,map02025	M00509	-	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GGDEF,HATPase_c,Response_reg
CMS1_k127_2720434_4	105559.Nwat_0553	2.93e-169	543.0	COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,1RMR2@1236|Gammaproteobacteria,1WW1H@135613|Chromatiales	135613|Chromatiales	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
CMS1_k127_2720434_1	1249627.D779_0578	5.221e-300	930.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,1RME8@1236|Gammaproteobacteria,1WX7K@135613|Chromatiales	135613|Chromatiales	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
CMS1_k127_2720434_15	765914.ThisiDRAFT_2000	4.659e-61	217.0	COG0293@1|root,COG0293@2|Bacteria,1MW1C@1224|Proteobacteria,1RN5M@1236|Gammaproteobacteria,1WX98@135613|Chromatiales	135613|Chromatiales	J	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit	ftsJ	-	2.1.1.166	ko:K02427	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ
CMS1_k127_2720434_16	187272.Mlg_1980	1.022e-59	210.0	COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,1S3UP@1236|Gammaproteobacteria,1WY5U@135613|Chromatiales	135613|Chromatiales	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
CMS1_k127_2720434_0	1049564.TevJSym_ap00720	0.0	1630.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,1RPIU@1236|Gammaproteobacteria,1J5E8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Carbamoyl-phosphate synthetase ammonia chain	carB	GO:0000050,GO:0000166,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016597,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b0033,iBWG_1329.BWG_0031,iECDH10B_1368.ECDH10B_0034,iECDH1ME8569_1439.ECDH1ME8569_0031,iECUMN_1333.ECUMN_0034,iEcDH1_1363.EcDH1_3566,iJN746.PP_4723,iJO1366.b0033,iJR904.b0033,iPC815.YPO0482,iY75_1357.Y75_RS00170,iYL1228.KPN_00041	CPSase_L_D2,CPSase_L_D3,MGS
CMS1_k127_2720434_3	395493.BegalDRAFT_1423	7.028e-176	557.0	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,1RMAW@1236|Gammaproteobacteria,45ZMY@72273|Thiotrichales	72273|Thiotrichales	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
CMS1_k127_2720434_13	391625.PPSIR1_08881	8.138e-69	245.0	COG0121@1|root,COG0121@2|Bacteria	2|Bacteria	S	cellular modified histidine biosynthetic process	egtC	-	-	ko:K18802	-	-	-	-	ko00000	-	-	-	GATase_4
CMS1_k127_2720434_10	1123368.AUIS01000003_gene1814	1.179e-99	330.0	COG3271@1|root,COG3271@2|Bacteria,1RAD5@1224|Proteobacteria,1SNN0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
CMS1_k127_2720434_2	1123393.KB891326_gene66	6.24e-213	671.0	COG0189@1|root,COG0189@2|Bacteria,1MX5X@1224|Proteobacteria,2VJP0@28216|Betaproteobacteria,1KS9Q@119069|Hydrogenophilales	119069|Hydrogenophilales	HJ	RimK-like ATPgrasp N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RLAN
CMS1_k127_2720434_5	1232410.KI421415_gene2974	1.885e-135	444.0	COG2170@1|root,COG2170@2|Bacteria,1MY35@1224|Proteobacteria,42PBG@68525|delta/epsilon subdivisions,2WK4S@28221|Deltaproteobacteria,43UJW@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Glutamate-cysteine ligase family 2(GCS2)	-	-	-	-	-	-	-	-	-	-	-	-	GCS2
CMS1_k127_2720434_14	1123368.AUIS01000003_gene1811	2.733e-65	231.0	COG3931@1|root,COG3931@2|Bacteria,1QEPD@1224|Proteobacteria,1S4RU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	N-formylglutamate amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FGase
CMS1_k127_2720434_21	414684.RC1_2356	2.254e-32	128.0	COG2146@1|root,COG2146@2|Bacteria,1N72F@1224|Proteobacteria,2UFDN@28211|Alphaproteobacteria,2JTWK@204441|Rhodospirillales	204441|Rhodospirillales	P	COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
CMS1_k127_2720434_6	1123392.AQWL01000002_gene2034	3.991e-130	421.0	COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,2VIFE@28216|Betaproteobacteria,1KRBV@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
CMS1_k127_2720434_12	765913.ThidrDRAFT_0183	9.146e-71	246.0	COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,1RMXQ@1236|Gammaproteobacteria,1WX46@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
CMS1_k127_2720434_22	765910.MARPU_16705	1.197e-22	102.0	COG2921@1|root,COG2921@2|Bacteria,1RGV5@1224|Proteobacteria,1S61Y@1236|Gammaproteobacteria,1WZ34@135613|Chromatiales	135613|Chromatiales	S	Belongs to the UPF0250 family	-	-	-	ko:K09158	-	-	-	-	ko00000	-	-	-	DUF493
CMS1_k127_2720434_24	314278.NB231_11754	2.561e-12	70.0	2E80T@1|root,332F0@2|Bacteria,1N7RY@1224|Proteobacteria,1SCE8@1236|Gammaproteobacteria,1X1Y4@135613|Chromatiales	135613|Chromatiales	S	Domain of unknown function (DUF4389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4389
CMS1_k127_2720434_23	65672.G4TW49	1.279e-13	82.0	COG0664@1|root,KOG1113@2759|Eukaryota,38GS1@33154|Opisthokonta,3NU9Z@4751|Fungi,3UZXM@5204|Basidiomycota,2273R@155619|Agaricomycetes,3H2BC@355688|Agaricomycetes incertae sedis	4751|Fungi	T	Camp-dependent protein kinase regulatory subunit	PKAR	GO:0000003,GO:0000228,GO:0000785,GO:0000790,GO:0001932,GO:0001933,GO:0002831,GO:0002832,GO:0003674,GO:0004857,GO:0004860,GO:0004862,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0005886,GO:0006469,GO:0006950,GO:0006979,GO:0007154,GO:0008104,GO:0008150,GO:0008603,GO:0009266,GO:0009267,GO:0009405,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009653,GO:0009892,GO:0009966,GO:0009968,GO:0009987,GO:0009991,GO:0010563,GO:0010570,GO:0010605,GO:0010639,GO:0010646,GO:0010648,GO:0016020,GO:0019207,GO:0019210,GO:0019220,GO:0019222,GO:0019887,GO:0019954,GO:0022603,GO:0023051,GO:0023057,GO:0030154,GO:0030234,GO:0030291,GO:0030435,GO:0030436,GO:0030447,GO:0030448,GO:0031279,GO:0031281,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0031667,GO:0031668,GO:0031669,GO:0031974,GO:0031981,GO:0032101,GO:0032102,GO:0032104,GO:0032105,GO:0032107,GO:0032108,GO:0032268,GO:0032269,GO:0032502,GO:0033036,GO:0033043,GO:0033554,GO:0033673,GO:0034305,GO:0034599,GO:0034605,GO:0034613,GO:0036170,GO:0036180,GO:0040007,GO:0040008,GO:0042173,GO:0042221,GO:0042325,GO:0042326,GO:0042594,GO:0043085,GO:0043086,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043549,GO:0043934,GO:0043936,GO:0043937,GO:0043938,GO:0043943,GO:0043945,GO:0044092,GO:0044093,GO:0044182,GO:0044419,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044454,GO:0044464,GO:0045595,GO:0045597,GO:0045761,GO:0045762,GO:0045859,GO:0045881,GO:0045926,GO:0045936,GO:0046578,GO:0046580,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048646,GO:0048856,GO:0048869,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051056,GO:0051058,GO:0051094,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051174,GO:0051179,GO:0051246,GO:0051248,GO:0051338,GO:0051339,GO:0051348,GO:0051349,GO:0051641,GO:0051704,GO:0051716,GO:0051783,GO:0051784,GO:0060255,GO:0060258,GO:0065007,GO:0065009,GO:0070013,GO:0070727,GO:0070887,GO:0071496,GO:0071900,GO:0071901,GO:0071944,GO:0080090,GO:0080134,GO:0097271,GO:0098772,GO:1900428,GO:1900429,GO:1900434,GO:1900435,GO:1900443,GO:1900444,GO:1902531,GO:1902532,GO:1903664,GO:1903666	-	ko:K04739	ko04910,map04910	-	-	-	ko00000,ko00001	-	-	-	RIIa,cNMP_binding
CMS1_k127_2720434_8	519989.ECTPHS_03392	6.903e-127	412.0	COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,1RMC5@1236|Gammaproteobacteria,1WWXT@135613|Chromatiales	135613|Chromatiales	V	PFAM ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_2720434_9	1042375.AFPL01000018_gene287	3.303e-107	355.0	COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,1RP0Z@1236|Gammaproteobacteria,46426@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	Transport permease protein	yadH	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
CMS1_k127_2720434_18	1211114.ALIP01000105_gene1709	1.266e-52	187.0	COG0720@1|root,COG0720@2|Bacteria,1RI4P@1224|Proteobacteria,1S3T6@1236|Gammaproteobacteria,1X6I0@135614|Xanthomonadales	135614|Xanthomonadales	H	synthase	ptpS	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
CMS1_k127_2720434_11	472759.Nhal_0576	4.395e-94	316.0	COG0115@1|root,COG0115@2|Bacteria,1MVAT@1224|Proteobacteria,1RPU0@1236|Gammaproteobacteria,1WX40@135613|Chromatiales	135613|Chromatiales	EH	PFAM Aminotransferase, class IV	-	-	2.6.1.21	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	-	R01148,R01582,R02459,R02851,R02924,R05053	RC00006,RC00008,RC00025	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4
CMS1_k127_2720434_7	1232683.ADIMK_1019	3.936e-128	419.0	COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,1RMJA@1236|Gammaproteobacteria,4646M@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Belongs to the peptidase S11 family	dacA	GO:0000270,GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	iEC55989_1330.EC55989_2269,iSFV_1184.SFV_0694,iSbBS512_1146.SbBS512_E2506,iYL1228.KPN_00664	PBP5_C,Peptidase_S11
CMS1_k127_2720434_20	1163409.UUA_12208	2.721e-48	177.0	COG0797@1|root,COG3087@1|root,COG0797@2|Bacteria,COG3087@2|Bacteria,1MZ8S@1224|Proteobacteria,1RMCG@1236|Gammaproteobacteria,1X3Q2@135614|Xanthomonadales	135614|Xanthomonadales	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,SPOR
CMS1_k127_2740320_2	448385.sce5468	1.275e-71	249.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,42MEM@68525|delta/epsilon subdivisions,2WKYA@28221|Deltaproteobacteria,2YU1C@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	kefB	-	-	ko:K03455,ko:K11745,ko:K11747	-	-	-	-	ko00000,ko02000	2.A.37,2.A.37.1.1,2.A.37.1.2	-	-	Na_H_Exchanger,TrkA_N
CMS1_k127_2740320_4	1283300.ATXB01000001_gene536	1.068e-38	152.0	COG3212@1|root,COG3212@2|Bacteria,1N2PN@1224|Proteobacteria,1T8Q0@1236|Gammaproteobacteria,1XFJ1@135618|Methylococcales	135618|Methylococcales	S	Peptidase propeptide and YPEB domain	-	-	-	-	-	-	-	-	-	-	-	-	PepSY
CMS1_k127_2740320_1	1122194.AUHU01000004_gene1491	3.127e-98	326.0	COG3484@1|root,COG3484@2|Bacteria,1N057@1224|Proteobacteria,1RRR0@1236|Gammaproteobacteria,466NX@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	PFAM 20S proteasome, A and B subunits	-	-	-	ko:K07395	-	-	-	-	ko00000	-	-	-	Proteasome
CMS1_k127_2740320_0	1249627.D779_1402	4.69e-103	343.0	COG1305@1|root,COG4196@1|root,COG1305@2|Bacteria,COG4196@2|Bacteria,1MVAG@1224|Proteobacteria,1RMX2@1236|Gammaproteobacteria,1WW9S@135613|Chromatiales	135613|Chromatiales	E	Bacterial transglutaminase-like N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,DUF2126,Transglut_core
CMS1_k127_2740320_3	1209072.ALBT01000066_gene1094	5.605e-45	167.0	COG2307@1|root,COG2307@2|Bacteria,1MVZK@1224|Proteobacteria,1RN2Y@1236|Gammaproteobacteria,1FGDP@10|Cellvibrio	1236|Gammaproteobacteria	S	A predicted alpha-helical domain with a conserved ER motif.	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E
CMS1_k127_2834390_4	396588.Tgr7_0199	8.296e-58	208.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,1RQ8B@1236|Gammaproteobacteria,1WXE6@135613|Chromatiales	135613|Chromatiales	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,PAS_8
CMS1_k127_2834390_1	1049564.TevJSym_ag01000	9.699e-149	484.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RRXX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Response regulator receiver	ntrX	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activ_2,Sigma54_activat
CMS1_k127_2834390_5	1255043.TVNIR_2245	1.415e-51	189.0	COG2227@1|root,COG2227@2|Bacteria,1RE7I@1224|Proteobacteria,1S6PD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	PFAM Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25,TehB
CMS1_k127_2834390_6	395493.BegalDRAFT_2958	1.144e-30	124.0	COG3063@1|root,COG3063@2|Bacteria,1QV1V@1224|Proteobacteria,1SRHP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_19
CMS1_k127_2834390_7	1279038.KB907356_gene2016	5.722e-26	121.0	COG4625@1|root,COG4625@2|Bacteria,1NGYG@1224|Proteobacteria,2UMI6@28211|Alphaproteobacteria,2JWEX@204441|Rhodospirillales	204441|Rhodospirillales	S	Autotransporter beta-domain	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter
CMS1_k127_2834390_0	713586.KB900536_gene2073	1.507e-159	507.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,1T02D@1236|Gammaproteobacteria,1WW5T@135613|Chromatiales	135613|Chromatiales	F	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
CMS1_k127_2834390_3	105559.Nwat_0265	5.21e-61	213.0	COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,1S3PI@1236|Gammaproteobacteria,1WY8C@135613|Chromatiales	135613|Chromatiales	J	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
CMS1_k127_2834390_2	395493.BegalDRAFT_1769	4.414e-101	339.0	COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,1RPQ7@1236|Gammaproteobacteria,45ZQK@72273|Thiotrichales	72273|Thiotrichales	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
CMS1_k127_2846251_5	1123368.AUIS01000004_gene237	3.528e-61	213.0	COG0780@1|root,COG0780@2|Bacteria,1MW0M@1224|Proteobacteria,1RNXM@1236|Gammaproteobacteria,2NCX7@225057|Acidithiobacillales	225057|Acidithiobacillales	F	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
CMS1_k127_2846251_7	396588.Tgr7_2030	5.688e-59	212.0	COG2981@1|root,COG2981@2|Bacteria,1MVFT@1224|Proteobacteria,1RMQT@1236|Gammaproteobacteria,1WWYG@135613|Chromatiales	135613|Chromatiales	E	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway	cysZ	-	-	ko:K06203	-	-	-	-	ko00000	-	-	-	DnaJ,EI24
CMS1_k127_2846251_4	243233.MCA0517	1.107e-61	220.0	COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,1S47H@1236|Gammaproteobacteria,1XF2E@135618|Methylococcales	135618|Methylococcales	T	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
CMS1_k127_2846251_1	1163617.SCD_n02324	1.063e-92	312.0	COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,2VHYK@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon	gluQ	-	-	ko:K01894	-	-	-	-	ko00000,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c
CMS1_k127_2846251_3	1304883.KI912532_gene1921	1.204e-69	243.0	COG0518@1|root,COG0518@2|Bacteria,1MUDH@1224|Proteobacteria,2VJEI@28216|Betaproteobacteria,2KWJH@206389|Rhodocyclales	206389|Rhodocyclales	F	Glutamine amidotransferase class-I	-	-	-	-	-	-	-	-	-	-	-	-	GATase
CMS1_k127_2846251_9	95619.PM1_0201035	2.178e-44	169.0	COG3577@1|root,COG3577@2|Bacteria,1N2PE@1224|Proteobacteria,1S66F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Aspartyl protease	-	-	-	ko:K06985	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	gag-asp_proteas
CMS1_k127_2846251_6	1005048.CFU_0736	5.327e-60	213.0	COG2096@1|root,COG2096@2|Bacteria,1RDUF@1224|Proteobacteria,2VQ7P@28216|Betaproteobacteria,47268@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Cobalamin adenosyltransferase	yvqK	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
CMS1_k127_2846251_10	1379698.RBG1_1C00001G1383	5.577e-35	140.0	2CBKC@1|root,32RTJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2846251_0	247633.GP2143_00122	2.509e-107	372.0	COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,1RMFJ@1236|Gammaproteobacteria,1J5PW@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	TonB-dependent Receptor Plug Domain	-	-	-	ko:K02014,ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.3	-	-	Plug,TonB_dep_Rec
CMS1_k127_2846251_2	1041146.ATZB01000020_gene3731	3.442e-82	280.0	COG0500@1|root,COG2226@2|Bacteria,1MV4M@1224|Proteobacteria,2U6HF@28211|Alphaproteobacteria,4BAG1@82115|Rhizobiaceae	28211|Alphaproteobacteria	Q	Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM)	cmoA	-	-	ko:K15256	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_25
CMS1_k127_2846251_8	323261.Noc_2817	1.28e-47	175.0	COG2020@1|root,COG2020@2|Bacteria,1RJNV@1224|Proteobacteria,1SGB2@1236|Gammaproteobacteria,1X1KG@135613|Chromatiales	135613|Chromatiales	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
CMS1_k127_2881186_5	395493.BegalDRAFT_1792	2.035e-18	88.0	COG0287@1|root,COG0287@2|Bacteria,1QTZA@1224|Proteobacteria,1T20F@1236|Gammaproteobacteria,460DX@72273|Thiotrichales	72273|Thiotrichales	E	Prephenate dehydrogenase	-	-	1.3.1.12	ko:K00210,ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
CMS1_k127_2881186_1	395493.BegalDRAFT_1449	5.231e-145	469.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,1RP4T@1236|Gammaproteobacteria,45ZT5@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	-	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS1_k127_2881186_2	765914.ThisiDRAFT_0484	4.86e-138	447.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1MU60@1224|Proteobacteria,1RNRD@1236|Gammaproteobacteria,1WWFA@135613|Chromatiales	135613|Chromatiales	E	PFAM Prephenate dehydratase	-	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
CMS1_k127_2881186_4	857087.Metme_0631	4.403e-22	100.0	2FIY3@1|root,34AP0@2|Bacteria,1P269@1224|Proteobacteria,1SSJQ@1236|Gammaproteobacteria,1XGQ4@135618|Methylococcales	135618|Methylococcales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2881186_0	472759.Nhal_2629	4.764e-150	485.0	COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,1RMKU@1236|Gammaproteobacteria,1WWHV@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
CMS1_k127_2881186_3	395493.BegalDRAFT_2109	3.412e-122	398.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,1RN03@1236|Gammaproteobacteria,45ZYT@72273|Thiotrichales	72273|Thiotrichales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
CMS1_k127_2886094_6	857087.Metme_0534	8.361e-65	225.0	COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,1S3ST@1236|Gammaproteobacteria,1XF23@135618|Methylococcales	135618|Methylococcales	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
CMS1_k127_2886094_13	713586.KB900536_gene1761	1.072e-20	94.0	COG1977@1|root,COG1977@2|Bacteria,1NHG7@1224|Proteobacteria,1TK6F@1236|Gammaproteobacteria,1WZUM@135613|Chromatiales	135613|Chromatiales	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	moaD	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
CMS1_k127_2886094_9	396588.Tgr7_2952	3.53e-53	191.0	COG0314@1|root,COG0314@2|Bacteria,1RGUX@1224|Proteobacteria,1S5YH@1236|Gammaproteobacteria,1WYCE@135613|Chromatiales	135613|Chromatiales	H	PFAM molybdopterin biosynthesis MoaE	-	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
CMS1_k127_2886094_2	472759.Nhal_2468	7.725e-160	513.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,1RMQU@1236|Gammaproteobacteria,1WVYA@135613|Chromatiales	135613|Chromatiales	H	TIGRFAM molybdenum cofactor synthesis	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
CMS1_k127_2886094_10	395493.BegalDRAFT_1915	2.071e-51	189.0	COG1763@1|root,COG1763@2|Bacteria,1RD3Q@1224|Proteobacteria,1S72P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	molybdopterin-guanine dinucleotide biosynthesis protein	mobB	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363	2.7.7.77	ko:K03753,ko:K13818	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	iB21_1397.B21_03691,iBWG_1329.BWG_3527,iECBD_1354.ECBD_4174,iECDH1ME8569_1439.ECDH1ME8569_3728,iEcDH1_1363.EcDH1_4130,iJO1366.b3856,iSbBS512_1146.SbBS512_E4328,iY75_1357.Y75_RS17805	MobB
CMS1_k127_2886094_8	1123400.KB904771_gene3350	2.041e-58	209.0	COG0303@1|root,COG0746@1|root,COG1763@1|root,COG0303@2|Bacteria,COG0746@2|Bacteria,COG1763@2|Bacteria,1MVD5@1224|Proteobacteria,1RMQU@1236|Gammaproteobacteria,45ZST@72273|Thiotrichales	72273|Thiotrichales	H	MoeA N-terminal region (domain I and II)	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MobB,MoeA_C,MoeA_N,NTP_transf_3
CMS1_k127_2886094_14	196490.AUEZ01000010_gene2149	2.252e-15	83.0	2E7PS@1|root,3325B@2|Bacteria,1N7R7@1224|Proteobacteria,2UFCM@28211|Alphaproteobacteria,3K0ZR@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2886094_4	1122599.AUGR01000006_gene3861	1.077e-104	347.0	COG1526@1|root,COG1526@2|Bacteria,1MY28@1224|Proteobacteria,1RYH6@1236|Gammaproteobacteria,1XIQ8@135619|Oceanospirillales	135619|Oceanospirillales	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
CMS1_k127_2886094_3	765913.ThidrDRAFT_3324	2.614e-150	481.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,1RR68@1236|Gammaproteobacteria,1WW2B@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
CMS1_k127_2886094_0	1236959.BAMT01000005_gene170	3.301e-257	802.0	COG0477@1|root,COG2814@2|Bacteria,1QV32@1224|Proteobacteria,2VK3Z@28216|Betaproteobacteria,2KKFX@206350|Nitrosomonadales	206350|Nitrosomonadales	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_2886094_7	187272.Mlg_1325	1.165e-58	207.0	COG2954@1|root,COG2954@2|Bacteria,1RI38@1224|Proteobacteria,1S77V@1236|Gammaproteobacteria,1WYAI@135613|Chromatiales	135613|Chromatiales	S	PFAM Adenylate cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CYTH
CMS1_k127_2886094_1	686340.Metal_2681	7.123e-168	538.0	COG0477@1|root,COG2814@2|Bacteria,1MUZ8@1224|Proteobacteria,1T1NH@1236|Gammaproteobacteria,1XEBV@135618|Methylococcales	135618|Methylococcales	EGP	PFAM Major Facilitator Superfamily	-	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	MFS_1
CMS1_k127_2886094_11	512565.AMIS_18380	1.784e-33	131.0	COG3526@1|root,COG3526@2|Bacteria,2IRQ4@201174|Actinobacteria,4DK31@85008|Micromonosporales	201174|Actinobacteria	O	Rdx family	-	-	-	ko:K07401	-	-	-	-	ko00000	-	-	-	Rdx
CMS1_k127_2886094_5	395493.BegalDRAFT_2701	1.408e-72	267.0	COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,1RQVK@1236|Gammaproteobacteria,463M5@72273|Thiotrichales	72273|Thiotrichales	S	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
CMS1_k127_2886094_12	1121479.AUBS01000022_gene844	3.705e-28	131.0	COG0631@1|root,COG0631@2|Bacteria,1MVE7@1224|Proteobacteria,2U6K4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	COG0631 Serine threonine protein phosphatase	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
CMS1_k127_2897969_3	1158150.KB906246_gene1915	1.98e-83	280.0	COG0243@1|root,COG0243@2|Bacteria,1NSXR@1224|Proteobacteria,1T2GI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.7.5.1,1.8.5.3	ko:K00370,ko:K07306,ko:K17050	ko00910,ko00920,ko01120,ko02020,map00910,map00920,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497,R09501	RC02555,RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	5.A.3.1,5.A.3.3,5.A.3.8	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
CMS1_k127_2897969_6	1283300.ATXB01000001_gene1116	5.753e-07	52.0	COG1826@1|root,COG1826@2|Bacteria,1N6S4@1224|Proteobacteria,1SCC7@1236|Gammaproteobacteria,1XFSS@135618|Methylococcales	135618|Methylococcales	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	GO:0002790,GO:0003674,GO:0005215,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0034613,GO:0042886,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
CMS1_k127_2897969_7	1121033.AUCF01000001_gene2594	0.0009174	44.0	2AKUB@1|root,31BME@2|Bacteria,1Q7GI@1224|Proteobacteria,2VAS6@28211|Alphaproteobacteria,2JUGH@204441|Rhodospirillales	204441|Rhodospirillales	S	Hypoxia induced protein conserved region	-	-	-	-	-	-	-	-	-	-	-	-	HIG_1_N
CMS1_k127_2897969_4	395961.Cyan7425_2162	8.651e-19	98.0	COG2242@1|root,COG2242@2|Bacteria,1G3ZR@1117|Cyanobacteria,3KGHB@43988|Cyanothece	1117|Cyanobacteria	H	methyltransferase FkbM	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
CMS1_k127_2897969_5	1403819.BATR01000009_gene291	4.533e-10	64.0	2C7J2@1|root,33AYB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_2897969_1	697282.Mettu_3861	1.244e-184	588.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,1RN13@1236|Gammaproteobacteria,1XEMS@135618|Methylococcales	135618|Methylococcales	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
CMS1_k127_2897969_2	713586.KB900536_gene475	1.409e-125	411.0	COG0182@1|root,COG0182@2|Bacteria,1MUPM@1224|Proteobacteria,1RMGC@1236|Gammaproteobacteria,1WWQU@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
CMS1_k127_2897969_0	519989.ECTPHS_08231	2.555e-294	912.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,1RN03@1236|Gammaproteobacteria,1WXK8@135613|Chromatiales	135613|Chromatiales	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
CMS1_k127_2907026_4	400682.PAC_15711304	3.073e-88	292.0	COG0422@1|root,2QRQ4@2759|Eukaryota,38I15@33154|Opisthokonta,3BNVW@33208|Metazoa	33208|Metazoa	H	Phosphomethylpyrimidine synthase, chloroplastic-like	-	-	-	-	-	-	-	-	-	-	-	-	ThiC-associated,ThiC_Rad_SAM
CMS1_k127_2907026_13	1123368.AUIS01000014_gene2314	3.604e-65	239.0	COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,1RP9N@1236|Gammaproteobacteria,2NC9Z@225057|Acidithiobacillales	225057|Acidithiobacillales	H	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	-	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
CMS1_k127_2907026_16	1236902.ANAS01000015_gene520	9.316e-40	165.0	COG1391@1|root,COG1391@2|Bacteria,2GJ91@201174|Actinobacteria,4EFGN@85012|Streptosporangiales	201174|Actinobacteria	OT	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
CMS1_k127_2907026_21	7739.XP_002590720.1	1.998e-23	102.0	2CZEB@1|root,2S9YW@2759|Eukaryota,3AB3P@33154|Opisthokonta,3BUXI@33208|Metazoa,3DB54@33213|Bilateria	33208|Metazoa	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS1_k127_2907026_18	1173027.Mic7113_4120	1.189e-36	143.0	COG3453@1|root,COG3453@2|Bacteria,1G6UU@1117|Cyanobacteria,1HBJ5@1150|Oscillatoriales	1117|Cyanobacteria	S	Putative phosphatase (DUF442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF442
CMS1_k127_2907026_5	472759.Nhal_1378	4.367e-88	299.0	COG1028@1|root,COG1028@2|Bacteria,1MW9A@1224|Proteobacteria,1RMMZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
CMS1_k127_2907026_19	1101190.ARWB01000001_gene1273	1.121e-35	151.0	COG3659@1|root,COG3659@2|Bacteria,1QMC3@1224|Proteobacteria,2TU5Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	PFAM Carbohydrate-selective porin OprB	-	-	-	ko:K07267	-	-	-	-	ko00000,ko02000	1.B.19.1	-	-	OprB
CMS1_k127_2907026_20	1541065.JRFE01000039_gene6440	8.777e-30	123.0	COG2020@1|root,COG2020@2|Bacteria,1GB2G@1117|Cyanobacteria	1117|Cyanobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
CMS1_k127_2907026_10	686340.Metal_2855	3.087e-81	275.0	COG0503@1|root,COG0503@2|Bacteria,1MVZ6@1224|Proteobacteria,1S2N9@1236|Gammaproteobacteria,1XEUU@135618|Methylococcales	135618|Methylococcales	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
CMS1_k127_2907026_17	1123368.AUIS01000010_gene2379	1.143e-38	148.0	COG2259@1|root,COG2259@2|Bacteria,1MZVP@1224|Proteobacteria,1S8UI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	membrane	yqjF	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
CMS1_k127_2907026_6	948106.AWZT01000031_gene1306	1.344e-86	293.0	COG1656@1|root,COG1656@2|Bacteria,1R442@1224|Proteobacteria,2VN8Q@28216|Betaproteobacteria,1K0IY@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Mut7-C RNAse domain	-	-	-	ko:K09122	-	-	-	-	ko00000	-	-	-	Mut7-C,Ub-Mut7C
CMS1_k127_2907026_9	243233.MCA0045	6.482e-84	285.0	COG1515@1|root,COG1515@2|Bacteria,1MWRN@1224|Proteobacteria,1RRYH@1236|Gammaproteobacteria,1XG9S@135618|Methylococcales	135618|Methylococcales	L	Endonuclease V	-	-	3.1.21.7	ko:K05982	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Endonuclease_5
CMS1_k127_2907026_8	296591.Bpro_4278	1.024e-84	287.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,2VQ3B@28216|Betaproteobacteria,4AACE@80864|Comamonadaceae	28216|Betaproteobacteria	O	protein-L-isoaspartate O-methyltransferase	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
CMS1_k127_2907026_0	1122135.KB893134_gene3970	6.644e-223	713.0	COG0204@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,1MWDY@1224|Proteobacteria,2TTGI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	Major facilitator Superfamily	aas	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase,MFS_1
CMS1_k127_2907026_2	1260251.SPISAL_06305	2.202e-149	489.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,1RMFZ@1236|Gammaproteobacteria,1WXD7@135613|Chromatiales	135613|Chromatiales	M	lytic transglycosylase	-	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
CMS1_k127_2907026_12	472759.Nhal_3458	7.171e-66	233.0	COG0500@1|root,COG2226@2|Bacteria,1QTWC@1224|Proteobacteria,1RS4G@1236|Gammaproteobacteria,1WXQH@135613|Chromatiales	135613|Chromatiales	Q	PFAM methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS1_k127_2907026_11	1397527.Q670_05200	5.136e-69	237.0	COG0328@1|root,COG0328@2|Bacteria,1RCZ1@1224|Proteobacteria,1S3YC@1236|Gammaproteobacteria,1XJJ8@135619|Oceanospirillales	135619|Oceanospirillales	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
CMS1_k127_2907026_3	314278.NB231_01758	4.257e-92	308.0	COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,1RNHQ@1236|Gammaproteobacteria,1WWJC@135613|Chromatiales	135613|Chromatiales	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
CMS1_k127_2907026_15	472759.Nhal_2273	6.232e-43	158.0	COG0278@1|root,COG0278@2|Bacteria,1MZ4V@1224|Proteobacteria,1S640@1236|Gammaproteobacteria,1WYMA@135613|Chromatiales	135613|Chromatiales	O	Belongs to the glutaredoxin family. Monothiol subfamily	-	-	-	ko:K07390	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Glutaredoxin
CMS1_k127_2907026_7	323261.Noc_1372	1.125e-85	288.0	COG3748@1|root,COG3748@2|Bacteria,1RFIZ@1224|Proteobacteria,1S8F8@1236|Gammaproteobacteria,1X0P1@135613|Chromatiales	135613|Chromatiales	S	Urate oxidase N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Urate_ox_N
CMS1_k127_2907026_1	631362.Thi970DRAFT_01081	1.68e-155	500.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,1RMV1@1236|Gammaproteobacteria,1WWNU@135613|Chromatiales	135613|Chromatiales	E	PFAM Aminotransferase class-III	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CMS1_k127_2907026_14	1121921.KB898711_gene2061	2.552e-58	211.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,1RQ59@1236|Gammaproteobacteria,2PMWC@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	E	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	argF	-	2.1.3.3,2.1.3.6,2.1.3.9	ko:K00611,ko:K09065,ko:K13252	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01398,R07245	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
CMS1_k127_2908643_0	472759.Nhal_2379	0.0	1372.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria,1WVVI@135613|Chromatiales	135613|Chromatiales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
CMS1_k127_2908643_2	247633.GP2143_18331	6.617e-67	229.0	COG0048@1|root,COG0048@2|Bacteria,1RCWY@1224|Proteobacteria,1S3WB@1236|Gammaproteobacteria,1J5YE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	GO:0000372,GO:0000375,GO:0000376,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015935,GO:0016070,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0031323,GO:0031325,GO:0032991,GO:0033120,GO:0034336,GO:0034337,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043484,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
CMS1_k127_2908643_3	395493.BegalDRAFT_2628	1.095e-65	227.0	COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,1RN77@1236|Gammaproteobacteria,460JG@72273|Thiotrichales	72273|Thiotrichales	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
CMS1_k127_2908643_1	765910.MARPU_03705	5.743e-158	502.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,1RNSZ@1236|Gammaproteobacteria,1WW0N@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
CMS1_k127_2929444_18	1453501.JELR01000002_gene1395	8.143e-10	71.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,COG3706@2|Bacteria,1PJCA@1224|Proteobacteria,1RS4H@1236|Gammaproteobacteria,4663N@72275|Alteromonadaceae	1236|Gammaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	ko:K21025	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	EAL,GGDEF,PAS,PAS_8,PAS_9,Response_reg
CMS1_k127_2929444_3	1042377.AFPJ01000043_gene837	1.674e-107	357.0	COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,1RM84@1236|Gammaproteobacteria,4651S@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	Lysine 2,3-aminomutase YodO family protein	epmB	GO:0003674,GO:0003824,GO:0005488,GO:0016853,GO:0016866,GO:0016869,GO:0048037,GO:0051536,GO:0051539,GO:0051540	5.4.3.2	ko:K01843,ko:K19810	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000,ko03012	-	-	iECH74115_1262.ECH74115_5662,iECIAI39_1322.ECIAI39_4611,iS_1188.S4569	Fer4_12,Fer4_14,Radical_SAM
CMS1_k127_2929444_5	857087.Metme_3752	4.156e-92	306.0	COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,1RPW7@1236|Gammaproteobacteria,1XE5P@135618|Methylococcales	135618|Methylococcales	J	Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
CMS1_k127_2929444_6	105559.Nwat_0492	2.703e-88	301.0	COG2269@1|root,COG2269@2|Bacteria,1MU97@1224|Proteobacteria,1RMR9@1236|Gammaproteobacteria,1WW5X@135613|Chromatiales	135613|Chromatiales	J	Elongation factor P--(R)-beta-lysine ligase	-	-	-	ko:K04568	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	tRNA-synt_2
CMS1_k127_2929444_0	472759.Nhal_2019	2.306e-193	622.0	COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,1RMNX@1236|Gammaproteobacteria,1WWG0@135613|Chromatiales	135613|Chromatiales	L	Helicase	-	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,Helicase_C_2
CMS1_k127_2929444_9	396588.Tgr7_0570	5.995e-70	246.0	COG1409@1|root,COG1409@2|Bacteria,1MWKX@1224|Proteobacteria,1RPA7@1236|Gammaproteobacteria,1WXST@135613|Chromatiales	135613|Chromatiales	S	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	cpdA	-	3.1.4.53	ko:K03651	ko00230,ko02025,map00230,map02025	-	R00191	RC00296	ko00000,ko00001,ko01000	-	-	-	Metallophos
CMS1_k127_2929444_17	160492.XF_1996	2.731e-11	70.0	COG1396@1|root,COG1396@2|Bacteria,1QU0W@1224|Proteobacteria,1T7C1@1236|Gammaproteobacteria,1X936@135614|Xanthomonadales	135614|Xanthomonadales	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
CMS1_k127_2929444_11	1144325.PMI22_05108	1.379e-53	196.0	COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,1RPYX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	COG1214 Inactive homolog of metal-dependent proteases	yeaZ	GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
CMS1_k127_2929444_1	323261.Noc_2669	1.879e-161	518.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,1RMP9@1236|Gammaproteobacteria,1WW0V@135613|Chromatiales	135613|Chromatiales	M	lipoprotein releasing system, transmembrane protein, LolC E family	-	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
CMS1_k127_2929444_7	1384054.N790_00015	2.788e-86	292.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,1RMWK@1236|Gammaproteobacteria,1X2X9@135614|Xanthomonadales	135614|Xanthomonadales	V	Part of the ABC transporter complex LolCDE involved in the translocation of	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
CMS1_k127_2929444_12	472759.Nhal_0531	2.525e-42	161.0	COG3216@1|root,COG3216@2|Bacteria,1RGV6@1224|Proteobacteria,1S682@1236|Gammaproteobacteria,1WYXK@135613|Chromatiales	135613|Chromatiales	S	Uncharacterized protein conserved in bacteria (DUF2062)	-	-	-	ko:K09928	-	-	-	-	ko00000	-	-	-	DUF2062
CMS1_k127_2929444_2	472759.Nhal_0530	1.878e-150	497.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,1RMW6@1236|Gammaproteobacteria,1WWQ3@135613|Chromatiales	135613|Chromatiales	S	DNA internalization-related competence protein ComEC Rec2	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
CMS1_k127_2929444_13	265072.Mfla_2093	2.16e-30	123.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,2VHKP@28216|Betaproteobacteria,2KMAI@206350|Nitrosomonadales	206350|Nitrosomonadales	S	DNA internalization-related competence protein ComEC Rec2	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
CMS1_k127_2929444_8	472759.Nhal_0529	4.851e-81	274.0	COG0811@1|root,COG0811@2|Bacteria,1QNJ1@1224|Proteobacteria,1RQWT@1236|Gammaproteobacteria,1WX5A@135613|Chromatiales	135613|Chromatiales	U	PFAM MotA TolQ ExbB proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
CMS1_k127_2929444_14	765914.ThisiDRAFT_2394	3.749e-29	121.0	COG0848@1|root,COG0848@2|Bacteria,1N0ZA@1224|Proteobacteria,1S90K@1236|Gammaproteobacteria,1WYEK@135613|Chromatiales	135613|Chromatiales	U	PFAM Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
CMS1_k127_2929444_4	765912.Thimo_3379	1.013e-104	350.0	COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,1RMMW@1236|Gammaproteobacteria,1WWWV@135613|Chromatiales	135613|Chromatiales	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
CMS1_k127_2929444_16	1121116.KB894769_gene1345	2.031e-17	83.0	COG2835@1|root,COG2835@2|Bacteria,1N6Y2@1224|Proteobacteria,2VW58@28216|Betaproteobacteria,4AFCV@80864|Comamonadaceae	28216|Betaproteobacteria	S	Belongs to the UPF0434 family	ycaR	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Trm112p
CMS1_k127_2929444_10	1415754.JQMK01000002_gene3538	1.778e-64	228.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,1RMAE@1236|Gammaproteobacteria,464GE@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005996,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008690,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019294,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046394,GO:0046400,GO:0046401,GO:0046872,GO:0070567,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iAF1260.b0918,iB21_1397.B21_00929,iBWG_1329.BWG_0770,iECBD_1354.ECBD_2677,iECB_1328.ECB_00922,iECDH10B_1368.ECDH10B_0988,iECDH1ME8569_1439.ECDH1ME8569_0869,iECD_1391.ECD_00922,iETEC_1333.ETEC_0986,iEcDH1_1363.EcDH1_2725,iEcHS_1320.EcHS_A1025,iEcolC_1368.EcolC_2678,iJO1366.b0918,iJR904.b0918,iPC815.YPO1400,iUMNK88_1353.UMNK88_1071,iY75_1357.Y75_RS04770	CTP_transf_3
CMS1_k127_2929444_15	338963.Pcar_1490	8.995e-19	96.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,42SUS@68525|delta/epsilon subdivisions,2WPPP@28221|Deltaproteobacteria,43SRP@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Sel1-like repeats.	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
CMS1_k127_3028425_10	1049564.TevJSym_ad00720	2.156e-92	311.0	COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,1RNHU@1236|Gammaproteobacteria,1J5B5@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009030,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009229,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042357,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iSFV_1184.SFV_0382	AIRS,AIRS_C
CMS1_k127_3028425_21	1121937.AUHJ01000018_gene242	2.756e-37	148.0	COG0781@1|root,COG0781@2|Bacteria,1RHFZ@1224|Proteobacteria,1S6AJ@1236|Gammaproteobacteria,467Y1@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
CMS1_k127_3028425_19	1123400.KB904753_gene1095	3.937e-47	173.0	COG0054@1|root,COG0054@2|Bacteria,1RD9J@1224|Proteobacteria,1S3WD@1236|Gammaproteobacteria,460J0@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
CMS1_k127_3028425_5	395493.BegalDRAFT_1167	1.823e-153	492.0	COG0108@1|root,COG0108@2|Bacteria,1MU8P@1224|Proteobacteria,1RQ49@1236|Gammaproteobacteria,45ZV7@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribB	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
CMS1_k127_3028425_16	765911.Thivi_1033	4.191e-59	210.0	COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,1RMSY@1236|Gammaproteobacteria,1WXA6@135613|Chromatiales	135613|Chromatiales	H	riboflavin synthase, alpha subunit	-	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
CMS1_k127_3028425_6	396588.Tgr7_1559	4.235e-118	390.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,1RN2M@1236|Gammaproteobacteria,1WVVQ@135613|Chromatiales	135613|Chromatiales	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
CMS1_k127_3028425_15	396588.Tgr7_1558	7.567e-63	220.0	COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,1S3P9@1236|Gammaproteobacteria,1WX91@135613|Chromatiales	135613|Chromatiales	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
CMS1_k127_3028425_2	349521.HCH_03860	3.713e-205	645.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,1RMHQ@1236|Gammaproteobacteria,1XH2G@135619|Oceanospirillales	135619|Oceanospirillales	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
CMS1_k127_3028425_8	187272.Mlg_0291	3.368e-101	338.0	COG2607@1|root,COG2607@2|Bacteria,1MVMX@1224|Proteobacteria,1RQKK@1236|Gammaproteobacteria,1WWDF@135613|Chromatiales	135613|Chromatiales	S	ATPase (AAA superfamily)	-	-	-	ko:K06923	-	-	-	-	ko00000	-	-	-	DUF815
CMS1_k127_3028425_17	105559.Nwat_2654	1.615e-56	202.0	COG0634@1|root,COG0634@2|Bacteria,1NRT8@1224|Proteobacteria,1RNPQ@1236|Gammaproteobacteria,1WWQX@135613|Chromatiales	135613|Chromatiales	F	phosphoribosyltransferase	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
CMS1_k127_3028425_9	243233.MCA1986	7.264e-93	311.0	COG0005@1|root,COG0005@2|Bacteria,1MUWW@1224|Proteobacteria,1RS0S@1236|Gammaproteobacteria,1XDU4@135618|Methylococcales	135618|Methylococcales	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine	-	-	2.4.2.44	ko:K19696	ko00270,ko01100,map00270,map01100	-	R09668	RC00063	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
CMS1_k127_3028425_22	317025.Tcr_1016	1.471e-26	113.0	2EQR5@1|root,33IB0@2|Bacteria,1NNKG@1224|Proteobacteria,1SIH5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3028425_18	580332.Slit_1271	3.856e-49	186.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria,44WDG@713636|Nitrosomonadales	28216|Betaproteobacteria	KLT	PFAM Serine threonine-protein kinase-like domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
CMS1_k127_3028425_4	1123392.AQWL01000010_gene2312	2.931e-156	503.0	COG2211@1|root,COG2211@2|Bacteria,1QVH9@1224|Proteobacteria,2WGR7@28216|Betaproteobacteria,1KSBE@119069|Hydrogenophilales	119069|Hydrogenophilales	G	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_3028425_12	631362.Thi970DRAFT_00643	6.898e-80	276.0	2C7Q9@1|root,2Z96K@2|Bacteria,1MWKA@1224|Proteobacteria,1RYMW@1236|Gammaproteobacteria,1WWWK@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3028425_23	472759.Nhal_2867	2.581e-15	84.0	2EC19@1|root,3360G@2|Bacteria,1PBYU@1224|Proteobacteria,1SD34@1236|Gammaproteobacteria,1X1CC@135613|Chromatiales	135613|Chromatiales	S	Peptidoglycan-binding protein, CsiV	-	-	-	-	-	-	-	-	-	-	-	-	CsiV
CMS1_k127_3028425_0	472759.Nhal_3142	0.0	1398.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,1RNCU@1236|Gammaproteobacteria,1WWJQ@135613|Chromatiales	135613|Chromatiales	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
CMS1_k127_3028425_11	396588.Tgr7_1547	3.169e-82	281.0	COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,1RNJR@1236|Gammaproteobacteria,1WW0C@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
CMS1_k127_3028425_7	395493.BegalDRAFT_1798	7.499e-111	371.0	COG2956@1|root,COG2956@2|Bacteria,1MVDP@1224|Proteobacteria,1RP29@1236|Gammaproteobacteria,460FI@72273|Thiotrichales	72273|Thiotrichales	G	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane	lapB	-	-	ko:K19804	-	-	-	-	ko00000	-	-	-	TPR_16
CMS1_k127_3028425_24	1123261.AXDW01000001_gene1060	7.211e-06	52.0	COG5416@1|root,COG5416@2|Bacteria,1NGPH@1224|Proteobacteria,1SGDB@1236|Gammaproteobacteria,1XBUT@135614|Xanthomonadales	135614|Xanthomonadales	S	Lipopolysaccharide assembly protein A domain	-	-	-	-	-	-	-	-	-	-	-	-	LapA_dom
CMS1_k127_3028425_20	713586.KB900536_gene485	2.905e-41	154.0	COG0776@1|root,COG0776@2|Bacteria,1MZ7M@1224|Proteobacteria,1S8XZ@1236|Gammaproteobacteria,1WYM5@135613|Chromatiales	135613|Chromatiales	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	himD	-	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
CMS1_k127_3028425_1	395493.BegalDRAFT_1796	1.527e-265	827.0	COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,1RMFY@1236|Gammaproteobacteria,45ZMR@72273|Thiotrichales	72273|Thiotrichales	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
CMS1_k127_3028425_13	314275.MADE_000001022110	1.985e-77	267.0	COG0283@1|root,COG0283@2|Bacteria,1MUUD@1224|Proteobacteria,1RNKT@1236|Gammaproteobacteria,466NJ@72275|Alteromonadaceae	1236|Gammaproteobacteria	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0015939,GO:0015940,GO:0015949,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iPC815.YPO1391,iSDY_1059.SDY_2348	Cytidylate_kin
CMS1_k127_3028425_3	519989.ECTPHS_08261	7.322e-162	520.0	COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,1RQ8U@1236|Gammaproteobacteria,1WX54@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
CMS1_k127_3028425_14	396588.Tgr7_1540	4.145e-76	262.0	COG0287@1|root,COG0287@2|Bacteria,1QTZA@1224|Proteobacteria,1T20F@1236|Gammaproteobacteria,1WW2D@135613|Chromatiales	135613|Chromatiales	E	PFAM Prephenate dehydrogenase	-	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
CMS1_k127_3057631_4	396588.Tgr7_0987	3.737e-74	249.0	COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,1RP4R@1236|Gammaproteobacteria,1WW6I@135613|Chromatiales	135613|Chromatiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
CMS1_k127_3057631_3	472759.Nhal_3698	1.39e-77	265.0	COG0852@1|root,COG0852@2|Bacteria,1MX4B@1224|Proteobacteria,1S2ET@1236|Gammaproteobacteria,1WWDD@135613|Chromatiales	135613|Chromatiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
CMS1_k127_3057631_1	472759.Nhal_3697	5.369e-251	778.0	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,1RM98@1236|Gammaproteobacteria,1WWN5@135613|Chromatiales	135613|Chromatiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
CMS1_k127_3057631_5	555778.Hneap_1960	4.004e-71	244.0	COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,1RN4C@1236|Gammaproteobacteria,1WWTG@135613|Chromatiales	135613|Chromatiales	C	TIGRFAM NADH-quinone oxidoreductase, E subunit	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
CMS1_k127_3057631_2	713586.KB900536_gene3048	2.137e-218	683.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,1RMUD@1236|Gammaproteobacteria,1WWH3@135613|Chromatiales	135613|Chromatiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
CMS1_k127_3057631_0	395493.BegalDRAFT_1884	4.722e-280	881.0	COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,1RMUH@1236|Gammaproteobacteria,45ZUB@72273|Thiotrichales	72273|Thiotrichales	C	NADH-quinone oxidoreductase	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
CMS1_k127_3057631_6	2340.JV46_20350	4.717e-63	223.0	COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,1RQE9@1236|Gammaproteobacteria,1J5UV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
CMS1_k127_30765_24	1173028.ANKO01000017_gene225	1.21e-15	79.0	COG0642@1|root,COG0745@1|root,COG2202@1|root,COG2203@1|root,COG3437@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3437@2|Bacteria,COG5002@2|Bacteria,1G09B@1117|Cyanobacteria,1H7M4@1150|Oscillatoriales	1117|Cyanobacteria	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_3,PAS_9,Response_reg
CMS1_k127_30765_7	395495.Lcho_0045	6.648e-120	396.0	COG2114@1|root,COG3437@1|root,COG2114@2|Bacteria,COG3437@2|Bacteria,1QY14@1224|Proteobacteria,2WH9F@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,Response_reg
CMS1_k127_30765_14	580332.Slit_2046	1.143e-72	265.0	COG4784@1|root,COG4784@2|Bacteria,1QXTD@1224|Proteobacteria,2WHJ6@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
CMS1_k127_30765_25	999141.GME_17823	1.296e-10	71.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,1RPI3@1236|Gammaproteobacteria,1XKF3@135619|Oceanospirillales	135619|Oceanospirillales	S	Sel1-like repeats.	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	SH3_3,Sel1
CMS1_k127_30765_3	580332.Slit_0533	4.776e-225	719.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,2VJ72@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Adenylyl cyclase class-3 4 guanylyl cyclase	cyaA	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
CMS1_k127_30765_0	1101191.KI912577_gene1272	0.0	1227.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,2TTAY@28211|Alphaproteobacteria,1JRYH@119045|Methylobacteriaceae	28211|Alphaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
CMS1_k127_30765_1	348824.LPU83_3247	0.0	1193.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2TQT0@28211|Alphaproteobacteria,4B8N8@82115|Rhizobiaceae	28211|Alphaproteobacteria	V	Efflux pump membrane transporter	bepG	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
CMS1_k127_30765_13	857087.Metme_0440	7.035e-91	312.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,1RMI7@1236|Gammaproteobacteria,1XEIA@135618|Methylococcales	135618|Methylococcales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K18298	-	M00641	-	-	ko00000,ko00002,ko01504,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_D23
CMS1_k127_30765_18	991905.SL003B_1472	9.111e-49	182.0	COG1309@1|root,COG1309@2|Bacteria,1MVQV@1224|Proteobacteria,2TRPA@28211|Alphaproteobacteria,4BS0D@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_11,TetR_N
CMS1_k127_30765_20	1122603.ATVI01000005_gene3042	1.892e-36	149.0	COG0668@1|root,COG0668@2|Bacteria,1N4UN@1224|Proteobacteria,1T9TX@1236|Gammaproteobacteria,1XBUR@135614|Xanthomonadales	135614|Xanthomonadales	M	Conserved TM helix	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel,TM_helix
CMS1_k127_30765_22	1122603.ATVI01000005_gene3041	9.156e-24	112.0	COG2239@1|root,COG2239@2|Bacteria,1NNAQ@1224|Proteobacteria,1SHM4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	MgtE intracellular N domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,MgtE_N
CMS1_k127_30765_9	1122603.ATVI01000005_gene3040	3.02e-113	379.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,1RNE4@1236|Gammaproteobacteria,1X4NW@135614|Xanthomonadales	1236|Gammaproteobacteria	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
CMS1_k127_30765_21	243233.MCA0562	1.333e-28	120.0	COG5622@1|root,COG5622@2|Bacteria,1N6XP@1224|Proteobacteria,1SCD9@1236|Gammaproteobacteria,1XFCP@135618|Methylococcales	135618|Methylococcales	N	Protein required for attachment to host cells	-	-	-	-	-	-	-	-	-	-	-	-	Host_attach
CMS1_k127_30765_4	472759.Nhal_0229	1.72e-151	496.0	COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,1MU9M@1224|Proteobacteria,1RPG3@1236|Gammaproteobacteria,1WW4S@135613|Chromatiales	135613|Chromatiales	S	AAA domain	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33,APH
CMS1_k127_30765_15	335543.Sfum_2864	9.97e-70	244.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,42QXM@68525|delta/epsilon subdivisions,2WMZI@28221|Deltaproteobacteria,2MRM3@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
CMS1_k127_30765_23	1123368.AUIS01000032_gene1389	6.317e-22	96.0	COG3360@1|root,COG3360@2|Bacteria	2|Bacteria	P	Dodecin	secE2	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
CMS1_k127_30765_16	765910.MARPU_02620	3.504e-67	237.0	COG0664@1|root,COG0664@2|Bacteria,1MVGE@1224|Proteobacteria,1RPTB@1236|Gammaproteobacteria,1WWQ7@135613|Chromatiales	135613|Chromatiales	K	Transcriptional regulator	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CMS1_k127_30765_2	622637.KE124774_gene3894	2.099e-245	772.0	COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,2TR7S@28211|Alphaproteobacteria,36XN8@31993|Methylocystaceae	28211|Alphaproteobacteria	I	Poly-beta-hydroxybutyrate polymerase N terminal	-	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	PHBC_N,PhaC_N
CMS1_k127_30765_5	261292.Nit79A3_2096	2.838e-127	413.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,2VIVB@28216|Betaproteobacteria,372AH@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
CMS1_k127_30765_17	1123228.AUIH01000004_gene1088	2.054e-60	223.0	COG3552@1|root,COG3552@2|Bacteria,1MUHH@1224|Proteobacteria,1RZ5Y@1236|Gammaproteobacteria,1XJEQ@135619|Oceanospirillales	135619|Oceanospirillales	S	COG3552 Protein containing von Willebrand factor type A (vWA) domain	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
CMS1_k127_30765_10	1411123.JQNH01000001_gene1485	5.281e-111	365.0	COG0714@1|root,COG0714@2|Bacteria,1MV5I@1224|Proteobacteria,2TREB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	COG0714 MoxR-like ATPases	coxD	-	-	-	-	-	-	-	-	-	-	-	AAA_5
CMS1_k127_30765_6	582744.Msip34_2351	9.217e-127	414.0	COG1054@1|root,COG1054@2|Bacteria,1MUFV@1224|Proteobacteria,2VIX6@28216|Betaproteobacteria,2KMBX@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Belongs to the UPF0176 family	-	-	-	ko:K07146	-	-	-	-	ko00000	-	-	-	Rhodanese
CMS1_k127_30765_19	1122599.AUGR01000001_gene183	6.486e-39	147.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,1S9DN@1236|Gammaproteobacteria,1XKPR@135619|Oceanospirillales	135619|Oceanospirillales	O	peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3
CMS1_k127_30765_8	386456.JQKN01000008_gene1387	3.951e-119	398.0	COG0477@1|root,arCOG00143@2157|Archaea,2XUTR@28890|Euryarchaeota,23PFA@183925|Methanobacteria	183925|Methanobacteria	G	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
CMS1_k127_30765_12	472759.Nhal_3537	8.394e-96	329.0	COG0665@1|root,COG0665@2|Bacteria	2|Bacteria	E	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	DAO
CMS1_k127_30765_11	1202962.KB907155_gene2968	6.178e-100	332.0	COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,1RNDE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
CMS1_k127_3091122_2	395493.BegalDRAFT_0278	1.029e-269	837.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,1RMTB@1236|Gammaproteobacteria,4600M@72273|Thiotrichales	72273|Thiotrichales	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
CMS1_k127_3091122_6	1049564.TevJSym_ab01230	3.381e-82	283.0	COG2242@1|root,COG2242@2|Bacteria,1R79F@1224|Proteobacteria,1RY3Z@1236|Gammaproteobacteria,1J8AJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	protein methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
CMS1_k127_3091122_8	261292.Nit79A3_2998	1.236e-38	150.0	COG2062@1|root,COG2062@2|Bacteria,1N0FX@1224|Proteobacteria,2VWT5@28216|Betaproteobacteria,3746Z@32003|Nitrosomonadales	28216|Betaproteobacteria	T	Phosphoglycerate mutase family	-	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1,NUDIX
CMS1_k127_3091122_4	261292.Nit79A3_2997	1.937e-179	575.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,2VI1K@28216|Betaproteobacteria,371PP@32003|Nitrosomonadales	28216|Betaproteobacteria	FP	Ppx GppA phosphatase	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
CMS1_k127_3091122_0	261292.Nit79A3_2996	0.0	1037.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,2VHH8@28216|Betaproteobacteria,371ZT@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
CMS1_k127_3091122_7	1026882.MAMP_00296	1.715e-80	274.0	COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,1RMW5@1236|Gammaproteobacteria,460YZ@72273|Thiotrichales	72273|Thiotrichales	P	Plays a role in the regulation of phosphate uptake	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
CMS1_k127_3091122_5	395493.BegalDRAFT_0873	1.139e-136	439.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,1RNUF@1236|Gammaproteobacteria,46073@72273|Thiotrichales	72273|Thiotrichales	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
CMS1_k127_3091122_3	323261.Noc_2397	1.183e-216	685.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,1RPV9@1236|Gammaproteobacteria,1WWYU@135613|Chromatiales	135613|Chromatiales	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,DUF3333
CMS1_k127_3091122_1	472759.Nhal_2290	1.098e-292	914.0	COG4590@1|root,COG4590@2|Bacteria,1QTTD@1224|Proteobacteria,1T1GK@1236|Gammaproteobacteria,1WXXX@135613|Chromatiales	135613|Chromatiales	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
CMS1_k127_3164037_0	1049564.TevJSym_at00030	3.82e-132	428.0	28I2K@1|root,2Z86N@2|Bacteria,1R1GA@1224|Proteobacteria,1RRPU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3164952_1	1234364.AMSF01000016_gene1545	5.741e-128	419.0	COG0475@1|root,COG0475@2|Bacteria,1RB9F@1224|Proteobacteria,1S398@1236|Gammaproteobacteria,1X5GT@135614|Xanthomonadales	135614|Xanthomonadales	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
CMS1_k127_3164952_3	671143.DAMO_1527	5.281e-119	390.0	COG0530@1|root,COG0530@2|Bacteria,2NPPD@2323|unclassified Bacteria	2|Bacteria	P	Sodium/calcium exchanger protein	yrbG	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
CMS1_k127_3164952_8	396588.Tgr7_0158	1.735e-41	156.0	2E4J2@1|root,32ZE4@2|Bacteria,1N7YM@1224|Proteobacteria,1S4GF@1236|Gammaproteobacteria,1WY9W@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF3775)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3775
CMS1_k127_3164952_5	631362.Thi970DRAFT_03839	1.305e-94	319.0	COG1446@1|root,COG1446@2|Bacteria,1MWFC@1224|Proteobacteria,1RNUR@1236|Gammaproteobacteria,1WYUF@135613|Chromatiales	135613|Chromatiales	E	Asparaginase	-	-	3.4.19.5	ko:K13051	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Asparaginase_2
CMS1_k127_3164952_4	204773.HEAR2554	3.541e-97	332.0	COG0477@1|root,COG2814@2|Bacteria,1MVUF@1224|Proteobacteria,2VNVS@28216|Betaproteobacteria,4759G@75682|Oxalobacteraceae	28216|Betaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
CMS1_k127_3164952_0	1123355.JHYO01000016_gene1850	3.149e-228	719.0	COG0388@1|root,COG1247@1|root,COG0388@2|Bacteria,COG1247@2|Bacteria,1MX4I@1224|Proteobacteria,2TVMQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,CN_hydrolase
CMS1_k127_3164952_2	331678.Cphamn1_1741	1.978e-121	397.0	COG1808@1|root,COG1808@2|Bacteria,1FEKP@1090|Chlorobi	1090|Chlorobi	S	Domain of unknown function (DUF389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF389
CMS1_k127_3164952_6	864051.BurJ1DRAFT_0529	4.363e-52	196.0	COG2014@1|root,COG2014@2|Bacteria,1MV5Z@1224|Proteobacteria,2VPCD@28216|Betaproteobacteria,1KM4B@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Putative heavy-metal chelation	-	-	-	-	-	-	-	-	-	-	-	-	DUF364,DUF4213
CMS1_k127_3164952_7	1123399.AQVE01000019_gene1632	1.671e-43	166.0	COG4094@1|root,COG4094@2|Bacteria,1RDHB@1224|Proteobacteria,1S78U@1236|Gammaproteobacteria,4634E@72273|Thiotrichales	72273|Thiotrichales	S	NnrU protein	-	-	-	-	-	-	-	-	-	-	-	-	NnrU
CMS1_k127_3164952_9	1298608.JCM18900_246	1.098e-16	82.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPWS@1236|Gammaproteobacteria,3NII1@468|Moraxellaceae	1236|Gammaproteobacteria	S	COG0488 ATPase components of ABC transporters with duplicated ATPase domains	yjjK	GO:0003674,GO:0003824,GO:0005488,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113	3.6.3.25	ko:K06020	-	-	-	-	ko00000,ko01000	-	-	-	ABC_tran,ABC_tran_Xtn
CMS1_k127_3181201_7	1000565.METUNv1_04010	7.852e-83	276.0	COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,2VIDR@28216|Betaproteobacteria,2KURP@206389|Rhodocyclales	206389|Rhodocyclales	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	-	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
CMS1_k127_3181201_10	883.DvMF_1537	1.169e-50	196.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,42MCG@68525|delta/epsilon subdivisions,2WKEQ@28221|Deltaproteobacteria,2MG0V@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
CMS1_k127_3181201_2	1049564.TevJSym_ah00230	6.997e-188	595.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,1RNAQ@1236|Gammaproteobacteria,1J4R1@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004828,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006434,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0010467,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iSDY_1059.SDY_2368	Seryl_tRNA_N,tRNA-synt_2b
CMS1_k127_3181201_14	323261.Noc_1035	2.096e-24	108.0	COG1993@1|root,COG1993@2|Bacteria,1N8TP@1224|Proteobacteria,1SDYH@1236|Gammaproteobacteria,1WZIY@135613|Chromatiales	135613|Chromatiales	S	Uncharacterized ACR, COG1993	-	-	-	ko:K09137	-	-	-	-	ko00000	-	-	-	DUF190
CMS1_k127_3181201_12	1049564.TevJSym_ah00210	1.659e-41	156.0	COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,1S8RQ@1236|Gammaproteobacteria,1J6UX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
CMS1_k127_3181201_1	472759.Nhal_3418	1.127e-194	615.0	COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,1RPBY@1236|Gammaproteobacteria,1WVV4@135613|Chromatiales	135613|Chromatiales	L	AAA ATPase, central domain protein	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
CMS1_k127_3181201_13	754477.Q7C_1651	1.407e-40	162.0	COG2834@1|root,COG2834@2|Bacteria,1PXDV@1224|Proteobacteria,1S9FW@1236|Gammaproteobacteria,460XC@72273|Thiotrichales	72273|Thiotrichales	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
CMS1_k127_3181201_0	545276.KB898724_gene2022	2.301e-262	828.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,1RM9A@1236|Gammaproteobacteria,1WWP6@135613|Chromatiales	135613|Chromatiales	D	DNA segregation ATPase FtsK SpoIIIE	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
CMS1_k127_3181201_3	396588.Tgr7_2006	6.438e-155	494.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,1RMEX@1236|Gammaproteobacteria,1WWPK@135613|Chromatiales	135613|Chromatiales	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
CMS1_k127_3181201_6	1173026.Glo7428_3262	4.984e-120	394.0	COG0604@1|root,COG0604@2|Bacteria,1FZW8@1117|Cyanobacteria	1117|Cyanobacteria	C	PFAM Alcohol dehydrogenase GroES-like domain	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N_2
CMS1_k127_3181201_9	1240350.AMZE01000011_gene3691	1.663e-56	203.0	COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,1S3PD@1236|Gammaproteobacteria,1YYR0@136845|Pseudomonas putida group	1236|Gammaproteobacteria	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015075,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
CMS1_k127_3181201_15	98439.AJLL01000052_gene3660	0.0003293	49.0	COG0604@1|root,COG0604@2|Bacteria,1FZW8@1117|Cyanobacteria,1JH4Q@1189|Stigonemataceae	1117|Cyanobacteria	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N_2
CMS1_k127_3181201_5	472759.Nhal_1062	1.114e-136	443.0	COG3608@1|root,COG3608@2|Bacteria,1MUAA@1224|Proteobacteria,1RNQQ@1236|Gammaproteobacteria,1WW1A@135613|Chromatiales	135613|Chromatiales	S	PFAM Succinylglutamate desuccinylase Aspartoacylase	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
CMS1_k127_3181201_4	1249627.D779_1090	1.21e-149	477.0	COG0189@1|root,COG0189@2|Bacteria,1MX62@1224|Proteobacteria,1RM8B@1236|Gammaproteobacteria,1WX7Z@135613|Chromatiales	135613|Chromatiales	HJ	Belongs to the RimK family	rimK	-	-	ko:K05844	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RimK
CMS1_k127_3181201_11	1265505.ATUG01000002_gene2121	1.122e-49	181.0	COG4067@1|root,COG4067@2|Bacteria,1RGX8@1224|Proteobacteria,43B1T@68525|delta/epsilon subdivisions	1224|Proteobacteria	O	Putative ATP-dependant zinc protease	-	-	-	-	-	-	-	-	-	-	-	-	Zn_protease
CMS1_k127_3181201_8	765910.MARPU_01890	7.847e-71	243.0	COG0221@1|root,COG0221@2|Bacteria,1RA2F@1224|Proteobacteria,1RPVD@1236|Gammaproteobacteria,1WWME@135613|Chromatiales	135613|Chromatiales	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
CMS1_k127_3188826_1	572477.Alvin_1851	1.703e-102	339.0	COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,1RMCZ@1236|Gammaproteobacteria,1WXGX@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
CMS1_k127_3188826_6	1453501.JELR01000005_gene1650	5.2e-28	118.0	COG0517@1|root,COG0517@2|Bacteria,1NAGC@1224|Proteobacteria,1SF8G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	CBS
CMS1_k127_3188826_0	583355.Caka_1487	8.977e-149	498.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	CarbopepD_reg_2,Plug,TonB_dep_Rec
CMS1_k127_3188826_2	156889.Mmc1_0937	7.422e-101	349.0	COG0515@1|root,COG0790@1|root,COG0515@2|Bacteria,COG0790@2|Bacteria,1PJRR@1224|Proteobacteria,2U625@28211|Alphaproteobacteria	28211|Alphaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	DUF4189,PG_binding_1,Pkinase,WD40
CMS1_k127_3188826_8	62928.azo3127	0.000369	46.0	2DZ51@1|root,34CFR@2|Bacteria,1P4XD@1224|Proteobacteria,2W5BH@28216|Betaproteobacteria,2KZF2@206389|Rhodocyclales	206389|Rhodocyclales	S	Domain of unknown function (DUF4124)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124
CMS1_k127_3188826_3	374847.Kcr_0915	2.284e-94	327.0	arCOG04118@1|root,arCOG04118@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3188826_7	713586.KB900536_gene1339	4.366e-23	108.0	COG2180@1|root,COG2180@2|Bacteria	2|Bacteria	C	chaperone-mediated protein complex assembly	-	-	-	-	-	-	-	-	-	-	-	-	EB_dh,Nitrate_red_del
CMS1_k127_3188826_4	1279019.ARQK01000058_gene745	1.973e-87	297.0	COG2180@1|root,COG2180@2|Bacteria	2|Bacteria	C	chaperone-mediated protein complex assembly	-	-	-	-	-	-	-	-	-	-	-	-	EB_dh,Nitrate_red_del
CMS1_k127_3188826_5	713586.KB900536_gene1341	1.491e-69	237.0	COG1140@1|root,COG1140@2|Bacteria,1MW9Q@1224|Proteobacteria,1RNMJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	nitrate reductase beta subunit	-	-	1.7.5.1	ko:K00371,ko:K17051	ko00910,ko01120,ko02020,map00910,map01120,map02020	M00529,M00530,M00804	R00798,R01106,R09497	RC02812	ko00000,ko00001,ko00002,ko01000,ko02000	5.A.3.1,5.A.3.8	-	-	Fer4_11
CMS1_k127_3228642_12	557598.LHK_00964	1.617e-08	55.0	COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,2VSJ2@28216|Betaproteobacteria,2KRFE@206351|Neisseriales	206351|Neisseriales	L	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	ybaB	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
CMS1_k127_3228642_6	1121013.P873_07065	2.04e-79	269.0	COG0353@1|root,COG0353@2|Bacteria,1MV9Q@1224|Proteobacteria,1RN99@1236|Gammaproteobacteria,1X30Z@135614|Xanthomonadales	135614|Xanthomonadales	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
CMS1_k127_3228642_11	1158165.KB898872_gene975	7.875e-15	79.0	COG2010@1|root,COG2010@2|Bacteria,1N71Z@1224|Proteobacteria,1SF76@1236|Gammaproteobacteria,1WZJF@135613|Chromatiales	135613|Chromatiales	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CMS1_k127_3228642_1	395493.BegalDRAFT_0885	2.58e-156	503.0	COG0501@1|root,COG0501@2|Bacteria,1MUXT@1224|Proteobacteria,1RNKP@1236|Gammaproteobacteria,45ZWZ@72273|Thiotrichales	72273|Thiotrichales	O	PFAM Peptidase family M48	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
CMS1_k127_3228642_7	1026882.MAMP_01660	1.758e-73	256.0	COG1949@1|root,COG1949@2|Bacteria,1R9WX@1224|Proteobacteria,1S217@1236|Gammaproteobacteria,460FA@72273|Thiotrichales	72273|Thiotrichales	L	3'-to-5' exoribonuclease specific for small oligoribonucleotides	orn	-	-	ko:K13288	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	RNase_T
CMS1_k127_3228642_0	1283300.ATXB01000001_gene1332	4.626e-167	539.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,1RMPS@1236|Gammaproteobacteria,1XEGQ@135618|Methylococcales	135618|Methylococcales	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
CMS1_k127_3228642_9	592316.Pat9b_3562	2.672e-40	154.0	COG0802@1|root,COG0802@2|Bacteria,1RGYU@1224|Proteobacteria,1S6IB@1236|Gammaproteobacteria,3W0N6@53335|Pantoea	1236|Gammaproteobacteria	S	possibly involved in cell wall synthesis	yjeE	GO:0000166,GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043531,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
CMS1_k127_3228642_3	1049564.TevJSym_bl00230	5.316e-139	454.0	COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,1RMP1@1236|Gammaproteobacteria,1J4PG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	N-acetylmuramoyl-L-alanine amidase	amiC	GO:0000003,GO:0000910,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0008745,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0019954,GO:0022402,GO:0022414,GO:0030288,GO:0030313,GO:0031975,GO:0032505,GO:0042597,GO:0043093,GO:0044464,GO:0051301,GO:0061783	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	iPC815.YPO1023,iSDY_1059.SDY_3034,iYL1228.KPN_03225	AMIN,Amidase_3,LysM
CMS1_k127_3228642_4	686340.Metal_1014	1.907e-126	425.0	COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,1RM89@1236|Gammaproteobacteria,1XDJ5@135618|Methylococcales	135618|Methylococcales	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
CMS1_k127_3228642_5	1294143.H681_22150	4.959e-103	345.0	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,1RMDU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0008033,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009451,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016070,GO:0016740,GO:0016765,GO:0019222,GO:0031323,GO:0031326,GO:0032268,GO:0033554,GO:0034248,GO:0034470,GO:0034605,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043555,GO:0044237,GO:0044238,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0051716,GO:0052381,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1990497,GO:2000112,GO:2000765	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
CMS1_k127_3228642_10	565045.NOR51B_145	3.293e-37	141.0	COG1923@1|root,COG1923@2|Bacteria,1MZM1@1224|Proteobacteria,1S8W0@1236|Gammaproteobacteria,1J6IZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs	hfq	GO:0003674,GO:0003676,GO:0003677,GO:0003681,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016246,GO:0016441,GO:0016458,GO:0017148,GO:0019222,GO:0022607,GO:0022613,GO:0022618,GO:0030423,GO:0031047,GO:0031123,GO:0031124,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032268,GO:0032269,GO:0032270,GO:0034248,GO:0034249,GO:0034250,GO:0034622,GO:0034641,GO:0035194,GO:0040029,GO:0040033,GO:0043170,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045974,GO:0045975,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:2000112,GO:2000113	-	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	-	-	-	ko00000,ko00001,ko03019,ko03036	-	-	-	Hfq
CMS1_k127_3228642_2	1232683.ADIMK_1305	9.293e-140	456.0	COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,1RN7V@1236|Gammaproteobacteria,464MZ@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006464,GO:0006468,GO:0006518,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006996,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018105,GO:0018193,GO:0018209,GO:0019001,GO:0019222,GO:0019538,GO:0019843,GO:0022411,GO:0030554,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0032790,GO:0032984,GO:0032988,GO:0034248,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0036211,GO:0036289,GO:0043021,GO:0043022,GO:0043023,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:2000112	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
CMS1_k127_3228642_8	395493.BegalDRAFT_0856	4.217e-46	171.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,1RMUG@1236|Gammaproteobacteria,45ZNE@72273|Thiotrichales	72273|Thiotrichales	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7,HflK_N
CMS1_k127_3278859_2	1026882.MAMP_01710	1.872e-89	300.0	COG3391@1|root,COG3391@2|Bacteria,1P862@1224|Proteobacteria,1RQZK@1236|Gammaproteobacteria,460F7@72273|Thiotrichales	72273|Thiotrichales	S	PQQ-dependent catabolism-associated beta-propeller protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1,Lactonase
CMS1_k127_3278859_4	243233.MCA0777	5.396e-73	252.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,1RQ1J@1236|Gammaproteobacteria,1XF2P@135618|Methylococcales	135618|Methylococcales	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
CMS1_k127_3278859_3	243233.MCA0778	8.281e-88	306.0	COG4585@1|root,COG4585@2|Bacteria,1RAPF@1224|Proteobacteria,1SYKU@1236|Gammaproteobacteria,1XH07@135618|Methylococcales	135618|Methylococcales	T	Histidine kinase	-	-	2.7.13.3	ko:K07675	ko02020,map02020	M00473	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3
CMS1_k127_3278859_5	105559.Nwat_2489	8.729e-67	236.0	COG1196@1|root,COG1196@2|Bacteria,1NGHR@1224|Proteobacteria,1RQW7@1236|Gammaproteobacteria,1X0VE@135613|Chromatiales	135613|Chromatiales	D	Protein of unknown function (DUF3450)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3450
CMS1_k127_3278859_1	472759.Nhal_3760	2.121e-104	357.0	COG0811@1|root,COG0811@2|Bacteria,1MX5J@1224|Proteobacteria,1RMSA@1236|Gammaproteobacteria,1X07Q@135613|Chromatiales	135613|Chromatiales	U	PFAM MotA TolQ ExbB proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
CMS1_k127_3278859_10	472759.Nhal_3759	1.659e-28	123.0	COG0811@1|root,COG0811@2|Bacteria,1MX60@1224|Proteobacteria,1RRX1@1236|Gammaproteobacteria,1X15P@135613|Chromatiales	135613|Chromatiales	U	PFAM MotA TolQ ExbB proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
CMS1_k127_3278859_8	472759.Nhal_3758	1.441e-39	151.0	COG0848@1|root,COG0848@2|Bacteria,1RI4M@1224|Proteobacteria,1S4GX@1236|Gammaproteobacteria,1X2G7@135613|Chromatiales	135613|Chromatiales	U	PFAM Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
CMS1_k127_3278859_9	1286106.MPL1_03668	1.557e-35	145.0	COG0810@1|root,COG0810@2|Bacteria,1PEDH@1224|Proteobacteria,1RRNT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
CMS1_k127_3278859_7	323261.Noc_0611	9.155e-52	198.0	COG0457@1|root,COG0457@2|Bacteria,1MVCA@1224|Proteobacteria,1RS02@1236|Gammaproteobacteria,1X1GJ@135613|Chromatiales	135613|Chromatiales	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
CMS1_k127_3278859_6	614083.AWQR01000001_gene3031	2.31e-59	216.0	COG0515@1|root,COG0745@1|root,COG0515@2|Bacteria,COG0745@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria	28216|Betaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K11912,ko:K12132	ko02025,ko03070,map02025,map03070	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02044	-	-	-	HAMP,Pkinase
CMS1_k127_3278859_12	1173020.Cha6605_1127	4.502e-08	62.0	COG2202@1|root,COG3437@1|root,COG3829@1|root,COG4251@1|root,COG2202@2|Bacteria,COG3437@2|Bacteria,COG3829@2|Bacteria,COG4251@2|Bacteria,1G0A1@1117|Cyanobacteria	1117|Cyanobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
CMS1_k127_3278859_0	697282.Mettu_3990	0.0	1299.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,1RNIF@1236|Gammaproteobacteria,1XE0G@135618|Methylococcales	135618|Methylococcales	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
CMS1_k127_3278859_11	697282.Mettu_2498	5.297e-28	115.0	COG0845@1|root,COG0845@2|Bacteria,1R6JG@1224|Proteobacteria,1SEA3@1236|Gammaproteobacteria,1XF38@135618|Methylococcales	135618|Methylococcales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_328851_31	472759.Nhal_1929	1.797e-33	132.0	COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,1S3RW@1236|Gammaproteobacteria,1WVXA@135613|Chromatiales	135613|Chromatiales	K	Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins	-	-	-	ko:K13643	-	-	-	-	ko00000,ko03000	-	-	-	Rrf2
CMS1_k127_328851_28	159450.NH14_21555	2.364e-36	141.0	COG0316@1|root,COG0316@2|Bacteria,1RH6T@1224|Proteobacteria,2VSKY@28216|Betaproteobacteria,1K7RI@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Belongs to the HesB IscA family	iscA	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
CMS1_k127_328851_0	472759.Nhal_0688	4.532e-260	806.0	COG0719@1|root,COG0719@2|Bacteria,1MVKY@1224|Proteobacteria,1RQ65@1236|Gammaproteobacteria,1WWT1@135613|Chromatiales	135613|Chromatiales	O	TIGRFAM FeS assembly protein SufB	-	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
CMS1_k127_328851_11	754477.Q7C_276	1.043e-113	371.0	COG0396@1|root,COG0396@2|Bacteria,1MUGK@1224|Proteobacteria,1RPFE@1236|Gammaproteobacteria,45ZRE@72273|Thiotrichales	72273|Thiotrichales	O	FeS assembly ATPase SufC	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
CMS1_k127_328851_12	105559.Nwat_0646	6.845e-113	379.0	COG0719@1|root,COG0719@2|Bacteria,1MVK0@1224|Proteobacteria,1RP2A@1236|Gammaproteobacteria,1WWK5@135613|Chromatiales	135613|Chromatiales	O	FeS assembly protein SufD	-	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
CMS1_k127_328851_3	472759.Nhal_0691	9.523e-183	580.0	COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,1RNIY@1236|Gammaproteobacteria,1WWTN@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5,SufE
CMS1_k127_328851_24	381666.H16_B1516	1.958e-53	192.0	COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,2VQ3A@28216|Betaproteobacteria,1K7JP@119060|Burkholderiaceae	28216|Betaproteobacteria	C	NifU-like N terminal domain	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
CMS1_k127_328851_20	314345.SPV1_11046	7.049e-60	214.0	COG2151@1|root,COG2151@2|Bacteria,1MZ9Y@1224|Proteobacteria	1224|Proteobacteria	S	FeS assembly SUF system protein	sufT	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
CMS1_k127_328851_29	713587.THITH_07310	6.05e-35	137.0	COG2146@1|root,COG2146@2|Bacteria,1N8PE@1224|Proteobacteria,1S6B0@1236|Gammaproteobacteria,1WYPJ@135613|Chromatiales	135613|Chromatiales	P	PFAM Rieske 2Fe-2S	-	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
CMS1_k127_328851_22	396588.Tgr7_2052	2.093e-58	206.0	COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,1S1Z3@1236|Gammaproteobacteria,1WYAE@135613|Chromatiales	135613|Chromatiales	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
CMS1_k127_328851_7	396588.Tgr7_2051	2.756e-139	452.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,1RMUI@1236|Gammaproteobacteria,1WWD4@135613|Chromatiales	135613|Chromatiales	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
CMS1_k127_328851_23	105559.Nwat_0768	3.219e-56	206.0	COG3063@1|root,COG3063@2|Bacteria,1MXPC@1224|Proteobacteria,1RY78@1236|Gammaproteobacteria,1WWUQ@135613|Chromatiales	135613|Chromatiales	NU	TIGRFAM type IV pilus biogenesis stability protein PilW	-	-	-	ko:K02656	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	LysM,TPR_10,TPR_14,TPR_16,TPR_17,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
CMS1_k127_328851_32	713586.KB900536_gene444	1.581e-27	123.0	COG1426@1|root,COG1426@2|Bacteria,1N240@1224|Proteobacteria,1RQMV@1236|Gammaproteobacteria,1WYDK@135613|Chromatiales	135613|Chromatiales	S	Domain of unknown function (DUF4115)	-	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25
CMS1_k127_328851_5	765914.ThisiDRAFT_0755	4.878e-165	529.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,1RPHI@1236|Gammaproteobacteria,1WWGZ@135613|Chromatiales	135613|Chromatiales	J	PFAM tRNA synthetase class II (G H P and S)	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
CMS1_k127_328851_26	1283300.ATXB01000001_gene1611	2.756e-44	168.0	COG2976@1|root,COG2976@2|Bacteria,1N117@1224|Proteobacteria,1S95P@1236|Gammaproteobacteria,1XF0Z@135618|Methylococcales	135618|Methylococcales	S	Tetratricopeptide repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	TPR_21
CMS1_k127_328851_14	395493.BegalDRAFT_3451	3.033e-106	357.0	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,1RN4V@1236|Gammaproteobacteria,460F4@72273|Thiotrichales	72273|Thiotrichales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamB	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
CMS1_k127_328851_6	1265313.HRUBRA_00459	1.869e-142	467.0	COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,1RMSF@1236|Gammaproteobacteria,1J4NG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	GO:0000027,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0022613,GO:0022618,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032794,GO:0034622,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0042273,GO:0043021,GO:0043022,GO:0043023,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0097159,GO:0097216,GO:0097367,GO:1901265,GO:1901363	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
CMS1_k127_328851_30	335283.Neut_0732	2.191e-34	145.0	COG3317@1|root,COG3317@2|Bacteria,1N670@1224|Proteobacteria,2VHS5@28216|Betaproteobacteria,371WT@32003|Nitrosomonadales	28216|Betaproteobacteria	M	NlpB/DapX lipoprotein	nlpB	-	-	ko:K07287	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	Lipoprotein_18
CMS1_k127_328851_9	1049564.TevJSym_ax00190	1.627e-130	422.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,1RNH9@1236|Gammaproteobacteria,1J4GE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008840,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0019877,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	iECP_1309.ECP_2492,iJN746.PP_1237,iYL1228.KPN_02812	DHDPS
CMS1_k127_328851_25	314278.NB231_12364	2.443e-51	188.0	COG2716@1|root,COG2716@2|Bacteria,1R7W7@1224|Proteobacteria,1RSDP@1236|Gammaproteobacteria,1WWJB@135613|Chromatiales	135613|Chromatiales	E	PFAM Amino acid-binding ACT	-	-	-	ko:K03567	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	ACT_6
CMS1_k127_328851_19	857087.Metme_2091	6.642e-64	223.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,1RQ7F@1236|Gammaproteobacteria,1XF8T@135618|Methylococcales	135618|Methylococcales	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
CMS1_k127_328851_4	1123073.KB899241_gene1855	1.955e-165	527.0	COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,1RMD9@1236|Gammaproteobacteria,1X3CD@135614|Xanthomonadales	135614|Xanthomonadales	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
CMS1_k127_328851_2	1071679.BG57_10360	3.262e-198	647.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,1K0RA@119060|Burkholderiaceae	28216|Betaproteobacteria	T	GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GAF_2,GGDEF,HAMP,PAS,PAS_4,PAS_8,PAS_9,dCache_3
CMS1_k127_328851_10	375286.mma_2039	7.249e-122	400.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,2VHBD@28216|Betaproteobacteria,47242@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	C-terminal region of band_7	qmcA	-	-	-	-	-	-	-	-	-	-	-	Band_7,Band_7_C
CMS1_k127_328851_33	580332.Slit_1574	1.414e-10	68.0	COG1585@1|root,COG1585@2|Bacteria,1PT3V@1224|Proteobacteria,2WADK@28216|Betaproteobacteria,44W42@713636|Nitrosomonadales	28216|Betaproteobacteria	OU	NfeD-like C-terminal, partner-binding	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
CMS1_k127_328851_27	1333507.AUTQ01000073_gene2105	3.679e-37	144.0	COG3296@1|root,COG3296@2|Bacteria,1RET3@1224|Proteobacteria,1S4H0@1236|Gammaproteobacteria,2Q2CW@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4870)	-	-	-	ko:K09940	-	-	-	-	ko00000	-	-	-	DUF4870
CMS1_k127_328851_13	291112.PAU_00068	3.652e-107	350.0	COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,1RN3K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0046914,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	iPC815.YPO0155,iYL1228.KPN_03757	Ribul_P_3_epim
CMS1_k127_328851_17	713587.THITH_15880	9.578e-84	283.0	COG0546@1|root,COG0546@2|Bacteria,1RDDY@1224|Proteobacteria,1S3QD@1236|Gammaproteobacteria,1WWPE@135613|Chromatiales	135613|Chromatiales	G	HAD-superfamily hydrolase, subfamily IA, variant 3	gph	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
CMS1_k127_328851_1	713586.KB900536_gene1668	1.002e-214	676.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,1WX6V@135613|Chromatiales	135613|Chromatiales	E	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
CMS1_k127_328851_16	247633.GP2143_13531	2.262e-91	310.0	COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,1RMQW@1236|Gammaproteobacteria,1J4YR@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	EH	COG0512 Anthranilate para-aminobenzoate synthases component II	pabA	GO:0000162,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006575,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009108,GO:0009308,GO:0009309,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042398,GO:0042401,GO:0042430,GO:0042435,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	2.6.1.85,4.1.3.27	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_3095,iEC042_1314.EC042_3623,iECABU_c1320.ECABU_c37840,iECED1_1282.ECED1_4024,iECNA114_1301.ECNA114_3463,iECOK1_1307.ECOK1_3780,iECP_1309.ECP_3451,iECS88_1305.ECS88_3751,iECSF_1327.ECSF_3187,iLF82_1304.LF82_1586,iNRG857_1313.NRG857_16660,iUMN146_1321.UM146_16880,iUTI89_1310.UTI89_C3863,ic_1306.c4135	GATase
CMS1_k127_328851_8	713586.KB900536_gene1665	5.793e-132	429.0	COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,1RNXV@1236|Gammaproteobacteria,1WW7U@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
CMS1_k127_328851_15	870187.Thini_0751	5.703e-97	323.0	COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,1RNYH@1236|Gammaproteobacteria,46069@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the TrpC family	trpC	-	4.1.1.48,5.3.1.24	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508,R03509	RC00944,RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS,PRAI
CMS1_k127_328851_18	1267005.KB911255_gene2616	2.881e-77	268.0	COG3391@1|root,COG3391@2|Bacteria,1RGAJ@1224|Proteobacteria,2U5SB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	SGL
CMS1_k127_328851_34	1122212.AULO01000007_gene2445	7.475e-05	49.0	2E214@1|root,32X90@2|Bacteria,1N3TR@1224|Proteobacteria,1SB5W@1236|Gammaproteobacteria,1XKKV@135619|Oceanospirillales	135619|Oceanospirillales	S	Phasin protein	-	-	-	-	-	-	-	-	-	-	-	-	Phasin_2
CMS1_k127_328851_21	215803.DB30_1753	1.13e-59	213.0	COG0235@1|root,COG0235@2|Bacteria,1MW7B@1224|Proteobacteria,42MF3@68525|delta/epsilon subdivisions,2WJXS@28221|Deltaproteobacteria,2YXMB@29|Myxococcales	28221|Deltaproteobacteria	G	Class II Aldolase and Adducin N-terminal domain	fucA	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
CMS1_k127_3303395_0	1123392.AQWL01000007_gene878	0.0	1182.0	COG0577@1|root,COG0577@2|Bacteria,1MW6D@1224|Proteobacteria,2VKF8@28216|Betaproteobacteria,1KSFY@119069|Hydrogenophilales	119069|Hydrogenophilales	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
CMS1_k127_3303395_5	1123392.AQWL01000007_gene876	3.411e-122	400.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2VJ7G@28216|Betaproteobacteria,1KSMU@119069|Hydrogenophilales	119069|Hydrogenophilales	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_3303395_2	1123368.AUIS01000017_gene2611	7.199e-207	652.0	COG0624@1|root,COG0624@2|Bacteria,1MW20@1224|Proteobacteria,1RPN7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	peptidase, M20	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
CMS1_k127_3303395_1	713586.KB900536_gene1899	1.558e-225	715.0	COG1166@1|root,COG1166@2|Bacteria,1MU80@1224|Proteobacteria,1RP2J@1236|Gammaproteobacteria,1WWBM@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the biosynthesis of agmatine from arginine	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N
CMS1_k127_3303395_8	857087.Metme_0199	2.951e-93	314.0	COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,1RQ2D@1236|Gammaproteobacteria,1XEAH@135618|Methylococcales	135618|Methylococcales	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_11,NAD_binding_2
CMS1_k127_3303395_10	269799.Gmet_2718	1.413e-82	287.0	COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,42T39@68525|delta/epsilon subdivisions,2WR3E@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KLT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
CMS1_k127_3303395_7	156889.Mmc1_1921	5.789e-98	343.0	COG0515@1|root,COG1262@1|root,COG3170@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,COG3170@2|Bacteria,1PJRR@1224|Proteobacteria,2U625@28211|Alphaproteobacteria	28211|Alphaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	DUF4189,PG_binding_1,Pkinase,WD40
CMS1_k127_3303395_9	1207063.P24_15846	1.083e-91	308.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,2U2JX@28211|Alphaproteobacteria,2JRBY@204441|Rhodospirillales	204441|Rhodospirillales	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_3303395_6	1123073.KB899242_gene1477	5.271e-113	369.0	COG1277@1|root,COG1277@2|Bacteria,1NZZ9@1224|Proteobacteria,1RP6C@1236|Gammaproteobacteria,1X35D@135614|Xanthomonadales	135614|Xanthomonadales	S	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
CMS1_k127_3303395_4	395493.BegalDRAFT_1705	3.762e-154	509.0	COG3225@1|root,COG3225@2|Bacteria,1MY63@1224|Proteobacteria,1RP5E@1236|Gammaproteobacteria,461IW@72273|Thiotrichales	72273|Thiotrichales	N	Gliding motility protein GldG	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
CMS1_k127_3303395_12	1469245.JFBG01000008_gene769	3.524e-27	124.0	2DM5E@1|root,31SVN@2|Bacteria,1MYKR@1224|Proteobacteria,1SF2N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
CMS1_k127_3303395_3	519989.ECTPHS_01399	4.524e-157	499.0	COG0752@1|root,COG0752@2|Bacteria,1MVCJ@1224|Proteobacteria,1RMYI@1236|Gammaproteobacteria,1WWUE@135613|Chromatiales	135613|Chromatiales	J	glycyl-tRNA synthetase alpha subunit	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2e
CMS1_k127_3303395_11	349521.HCH_00021	4.53e-76	265.0	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,1RNR3@1236|Gammaproteobacteria,1XH7W@135619|Oceanospirillales	135619|Oceanospirillales	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
CMS1_k127_331127_0	1049564.TevJSym_at00030	1.48e-129	421.0	28I2K@1|root,2Z86N@2|Bacteria,1R1GA@1224|Proteobacteria,1RRPU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3314392_2	1502770.JQMG01000001_gene1321	3.745e-75	259.0	COG5563@1|root,COG5563@2|Bacteria,1R9G5@1224|Proteobacteria,2VNH0@28216|Betaproteobacteria	28216|Betaproteobacteria	S	HAF family	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter
CMS1_k127_3314392_4	1123393.KB891316_gene1164	4.239e-45	181.0	COG3307@1|root,COG3307@2|Bacteria,1MYYP@1224|Proteobacteria,2WBZU@28216|Betaproteobacteria,1KSVQ@119069|Hydrogenophilales	119069|Hydrogenophilales	M	O-antigen ligase like membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
CMS1_k127_3314392_1	279714.FuraDRAFT_3582	1.566e-121	396.0	COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,2VH00@28216|Betaproteobacteria,2KQ12@206351|Neisseriales	206351|Neisseriales	M	Psort location Cytoplasmic, score 8.96	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
CMS1_k127_3314392_3	913865.DOT_4236	1.089e-48	185.0	COG4424@1|root,COG4424@2|Bacteria,1V5ZE@1239|Firmicutes,25053@186801|Clostridia	186801|Clostridia	S	PFAM Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1
CMS1_k127_3314392_0	56110.Oscil6304_0528	2.303e-124	417.0	COG2519@1|root,COG2519@2|Bacteria,1G473@1117|Cyanobacteria,1H810@1150|Oscillatoriales	1117|Cyanobacteria	J	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2,Methyltransf_23
CMS1_k127_3314392_5	467661.RKLH11_4308	8.49e-35	154.0	COG2931@1|root,COG3210@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
CMS1_k127_3332987_8	1249627.D779_1700	1.465e-91	320.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,1RMU1@1236|Gammaproteobacteria,1WWGW@135613|Chromatiales	135613|Chromatiales	L	TIGRFAM ATP-dependent helicase HrpA	-	-	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
CMS1_k127_3332987_3	207954.MED92_12266	1.389e-123	410.0	COG0475@1|root,COG0475@2|Bacteria,1QTSD@1224|Proteobacteria,1T1FK@1236|Gammaproteobacteria,1XHU6@135619|Oceanospirillales	135619|Oceanospirillales	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
CMS1_k127_3332987_9	713586.KB900536_gene245	7.479e-74	254.0	COG0599@1|root,COG2146@1|root,COG0599@2|Bacteria,COG2146@2|Bacteria,1RCCG@1224|Proteobacteria	1224|Proteobacteria	P	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD,Rieske
CMS1_k127_3332987_5	395493.BegalDRAFT_2161	2.783e-111	385.0	COG1305@1|root,COG1305@2|Bacteria,1QQE9@1224|Proteobacteria,1SK9H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
CMS1_k127_3332987_6	395493.BegalDRAFT_2160	4.031e-103	353.0	COG1721@1|root,COG1721@2|Bacteria,1MXDI@1224|Proteobacteria,1RQSS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
CMS1_k127_3332987_2	395493.BegalDRAFT_2249	7.383e-125	409.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,1RP45@1236|Gammaproteobacteria,45ZZF@72273|Thiotrichales	72273|Thiotrichales	S	PFAM ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
CMS1_k127_3332987_12	1502770.JQMG01000001_gene99	2.233e-67	235.0	COG0778@1|root,COG0778@2|Bacteria,1RA6E@1224|Proteobacteria,2VSIM@28216|Betaproteobacteria,2KKHC@206350|Nitrosomonadales	206350|Nitrosomonadales	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CMS1_k127_3332987_15	243365.CV_2787	9.841e-26	112.0	COG1188@1|root,COG1188@2|Bacteria,1MZR6@1224|Proteobacteria,2VTY8@28216|Betaproteobacteria,2KR8W@206351|Neisseriales	206351|Neisseriales	J	S4 domain protein	hslR	-	-	ko:K04762	-	-	-	-	ko00000,ko03110	-	-	-	S4
CMS1_k127_3332987_11	1283300.ATXB01000001_gene2306	3.81e-70	241.0	COG0521@1|root,COG0521@2|Bacteria,1R9W2@1224|Proteobacteria,1S21E@1236|Gammaproteobacteria,1XEKU@135618|Methylococcales	135618|Methylococcales	H	May be involved in the biosynthesis of molybdopterin	moaB	-	2.7.7.75	ko:K03638	ko00790,ko01100,map00790,map01100	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
CMS1_k127_3332987_14	998674.ATTE01000001_gene2679	2.973e-52	199.0	COG4246@1|root,COG4246@2|Bacteria,1RENT@1224|Proteobacteria,1S6FR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Esterase-like activity of phytase	-	-	-	-	-	-	-	-	-	-	-	-	Phytase-like
CMS1_k127_3332987_7	323261.Noc_0717	4.379e-92	316.0	COG1376@1|root,COG1388@1|root,COG1376@2|Bacteria,COG1388@2|Bacteria,1MVYT@1224|Proteobacteria,1RMNC@1236|Gammaproteobacteria,1WXGI@135613|Chromatiales	135613|Chromatiales	M	PFAM ErfK YbiS YcfS YnhG family protein	-	-	-	ko:K16291	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	SPOR,YkuD
CMS1_k127_3332987_16	1049564.TevJSym_aa00940	7.817e-09	60.0	2EFUG@1|root,339KM@2|Bacteria,1NGQQ@1224|Proteobacteria,1SHZI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	(Lipo)protein	oprI	-	-	-	-	-	-	-	-	-	-	-	Alanine_zipper
CMS1_k127_3332987_17	715451.ambt_10470	6.386e-06	53.0	COG3409@1|root,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	gspA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	PG_binding_1,YkuD
CMS1_k127_3332987_0	1173022.Cri9333_0794	4.049e-140	455.0	COG0436@1|root,COG0436@2|Bacteria,1G24E@1117|Cyanobacteria,1H6X1@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
CMS1_k127_3332987_10	1469245.JFBG01000011_gene834	1.615e-70	243.0	COG1403@1|root,COG1403@2|Bacteria,1MWEQ@1224|Proteobacteria,1S2R0@1236|Gammaproteobacteria,1WWXG@135613|Chromatiales	135613|Chromatiales	L	PFAM HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
CMS1_k127_3332987_13	266779.Meso_1611	7.06e-64	227.0	COG1694@1|root,COG3956@2|Bacteria,1MVKM@1224|Proteobacteria,2TRC9@28211|Alphaproteobacteria,43HXH@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Nucleoside triphosphate pyrophosphohydrolase	mazG	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009267,GO:0009394,GO:0009605,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042594,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658	3.6.1.9	ko:K02499,ko:K04765	ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100	-	R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R03004,R03036,R11323	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG
CMS1_k127_3332987_1	396588.Tgr7_0830	3.741e-127	411.0	COG1469@1|root,COG1469@2|Bacteria,1MV1B@1224|Proteobacteria,1RNDY@1236|Gammaproteobacteria,1WW3H@135613|Chromatiales	135613|Chromatiales	S	Converts GTP to 7,8-dihydroneopterin triphosphate	folE2	-	3.5.4.16	ko:K09007	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GCHY-1
CMS1_k127_3332987_4	765914.ThisiDRAFT_0858	1.234e-120	394.0	COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,1RMKY@1236|Gammaproteobacteria,1WX2E@135613|Chromatiales	135613|Chromatiales	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K00795,ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
CMS1_k127_3381108_0	224324.aq_1088	2.206e-130	443.0	COG0457@1|root,COG0457@2|Bacteria	224324.aq_1088|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3381108_1	1283300.ATXB01000001_gene904	4.225e-94	331.0	COG0457@1|root,COG0457@2|Bacteria,1MVMG@1224|Proteobacteria,1RNVA@1236|Gammaproteobacteria,1XFUV@135618|Methylococcales	135618|Methylococcales	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_5,TPR_1,TPR_2,TPR_8
CMS1_k127_3511835_31	155515.JP36_01980	1.608e-14	74.0	COG0668@1|root,COG0668@2|Bacteria,1N596@1224|Proteobacteria,1RQZP@1236|Gammaproteobacteria,1Y7A8@135625|Pasteurellales	135625|Pasteurellales	M	mechanosensitive channel	mscS	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel,TM_helix
CMS1_k127_3511835_17	187303.BN69_1463	1.157e-80	282.0	COG0644@1|root,COG0644@2|Bacteria	2|Bacteria	C	geranylgeranyl reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	DAO,FAD_binding_2,FAD_binding_3,FAD_oxidored,HI0933_like,Lycopene_cycl
CMS1_k127_3511835_26	1333998.M2A_2367	2.729e-46	176.0	COG3764@1|root,COG3764@2|Bacteria,1P806@1224|Proteobacteria,2U0A5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	PFAM peptidase C60, sortase A and B	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
CMS1_k127_3511835_2	330214.NIDE0941	1.013e-177	580.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
CMS1_k127_3511835_32	983545.Glaag_3910	8.53e-14	80.0	COG2885@1|root,COG2885@2|Bacteria,1RIG3@1224|Proteobacteria,1S8BF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_YMGG,OmpA
CMS1_k127_3511835_10	395493.BegalDRAFT_3010	3.516e-94	313.0	COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,1RM87@1236|Gammaproteobacteria,462JT@72273|Thiotrichales	72273|Thiotrichales	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_3511835_4	395493.BegalDRAFT_0266	2.621e-144	482.0	COG0642@1|root,COG2205@2|Bacteria,1N17V@1224|Proteobacteria,1RNFK@1236|Gammaproteobacteria,4615E@72273|Thiotrichales	72273|Thiotrichales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
CMS1_k127_3511835_7	857087.Metme_2069	2.439e-125	411.0	COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,1T1JB@1236|Gammaproteobacteria,1XEG6@135618|Methylococcales	135618|Methylococcales	C	Belongs to the AlaDH PNT family	-	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
CMS1_k127_3511835_24	1049564.TevJSym_ag00600	2.947e-65	250.0	COG0607@1|root,COG0664@1|root,COG0607@2|Bacteria,COG0664@2|Bacteria,1R9Q1@1224|Proteobacteria,1RSKD@1236|Gammaproteobacteria,1J6A4@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	PT	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,cNMP_binding
CMS1_k127_3511835_20	243233.MCA1917	3.373e-79	273.0	COG2961@1|root,COG2961@2|Bacteria,1MWGA@1224|Proteobacteria,1RNI1@1236|Gammaproteobacteria,1XEQ6@135618|Methylococcales	135618|Methylococcales	J	Specifically methylates the adenine in position 2030 of 23S rRNA	rlmJ	-	2.1.1.266	ko:K07115	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RsmJ
CMS1_k127_3511835_14	1415778.JQMM01000001_gene1034	1.089e-82	282.0	COG0613@1|root,COG0613@2|Bacteria,1MWIH@1224|Proteobacteria,1RNCG@1236|Gammaproteobacteria,1J600@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	metal-dependent phosphoesterases (PHP family)	trpH	GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004534,GO:0004536,GO:0004540,GO:0005488,GO:0006139,GO:0006259,GO:0006521,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008409,GO:0009987,GO:0010565,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016796,GO:0016895,GO:0016896,GO:0019222,GO:0030145,GO:0031323,GO:0033238,GO:0034641,GO:0035312,GO:0042578,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:0090357,GO:0090501,GO:0090503,GO:0140097,GO:0140098,GO:1901360	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
CMS1_k127_3511835_3	83406.HDN1F_02770	3.645e-150	484.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,1RNCW@1236|Gammaproteobacteria,1J542@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	flavoproteins	yhiN	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
CMS1_k127_3511835_29	382464.ABSI01000011_gene2694	3.52e-19	96.0	COG4508@1|root,COG4508@2|Bacteria,46VH7@74201|Verrucomicrobia	74201|Verrucomicrobia	S	dUTPase	-	-	-	-	-	-	-	-	-	-	-	-	dUTPase_2
CMS1_k127_3511835_11	1415780.JPOG01000001_gene2121	2.161e-92	312.0	COG4798@1|root,COG4798@2|Bacteria,1NNHX@1224|Proteobacteria,1RN1A@1236|Gammaproteobacteria,1X3E7@135614|Xanthomonadales	135614|Xanthomonadales	S	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3511835_18	1279038.KB907348_gene3100	1.291e-80	284.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2TR2B@28211|Alphaproteobacteria,2JQWU@204441|Rhodospirillales	204441|Rhodospirillales	O	COG0790 FOG TPR repeat, SEL1 subfamily	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
CMS1_k127_3511835_22	243233.MCA0799	6.403e-69	239.0	COG0235@1|root,COG0235@2|Bacteria,1RE8T@1224|Proteobacteria,1S3UF@1236|Gammaproteobacteria,1XDKT@135618|Methylococcales	135618|Methylococcales	G	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)	mtnB	-	4.2.1.109	ko:K08964	ko00270,ko01100,map00270,map01100	M00034	R07392	RC01939	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
CMS1_k127_3511835_16	686340.Metal_3599	1.141e-80	272.0	COG1791@1|root,COG1791@2|Bacteria,1RCZD@1224|Proteobacteria,1S42U@1236|Gammaproteobacteria,1XF09@135618|Methylococcales	135618|Methylococcales	S	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway	mtnD	-	1.13.11.53,1.13.11.54	ko:K08967	ko00270,ko01100,map00270,map01100	M00034	R07363,R07364	RC01866,RC02018,RC02118	ko00000,ko00001,ko00002,ko01000	-	-	-	ARD
CMS1_k127_3511835_19	768671.ThimaDRAFT_2053	1.267e-79	271.0	COG4229@1|root,COG4229@2|Bacteria,1R3V9@1224|Proteobacteria,1RP5Y@1236|Gammaproteobacteria,1WZWG@135613|Chromatiales	135613|Chromatiales	C	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)	mtnC	-	3.1.3.77	ko:K09880	ko00270,ko01100,map00270,map01100	M00034	R07395	RC02779	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD_2,Hydrolase
CMS1_k127_3511835_25	857087.Metme_4405	1.834e-48	176.0	COG3788@1|root,COG3788@2|Bacteria,1RDHP@1224|Proteobacteria,1S3PN@1236|Gammaproteobacteria,1XGJH@135618|Methylococcales	135618|Methylococcales	S	MAPEG family	-	-	-	ko:K07136	-	-	-	-	ko00000	-	-	-	MAPEG
CMS1_k127_3511835_13	318167.Sfri_3845	2.581e-84	297.0	COG2807@1|root,COG2807@2|Bacteria,1NXQ2@1224|Proteobacteria,1RXXM@1236|Gammaproteobacteria,2QABM@267890|Shewanellaceae	1236|Gammaproteobacteria	P	MFS_1 like family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
CMS1_k127_3511835_33	439235.Dalk_5048	5.917e-11	69.0	2DNXC@1|root,32ZN4@2|Bacteria,1NKWP@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3511835_28	1123392.AQWL01000002_gene1757	4.514e-21	97.0	2EH48@1|root,338P5@2|Bacteria,1NFS9@1224|Proteobacteria,2W6NA@28216|Betaproteobacteria,1KT6V@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3511835_30	485918.Cpin_1488	9.257e-15	81.0	COG0589@1|root,COG0589@2|Bacteria,4NWM6@976|Bacteroidetes	976|Bacteroidetes	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
CMS1_k127_3511835_5	1173028.ANKO01000174_gene2711	7.219e-142	460.0	COG1064@1|root,COG1064@2|Bacteria,1G327@1117|Cyanobacteria,1HEHF@1150|Oscillatoriales	1117|Cyanobacteria	S	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_3511835_12	156889.Mmc1_1921	1.123e-90	322.0	COG0515@1|root,COG1262@1|root,COG3170@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,COG3170@2|Bacteria,1PJRR@1224|Proteobacteria,2U625@28211|Alphaproteobacteria	28211|Alphaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	DUF4189,PG_binding_1,Pkinase,WD40
CMS1_k127_3511835_23	314278.NB231_15073	1.494e-67	235.0	COG0778@1|root,COG0778@2|Bacteria	2|Bacteria	C	coenzyme F420-1:gamma-L-glutamate ligase activity	yfhC	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CMS1_k127_3511835_1	396588.Tgr7_1237	3.468e-185	591.0	COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,1RN1Y@1236|Gammaproteobacteria,1WWI5@135613|Chromatiales	135613|Chromatiales	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
CMS1_k127_3511835_15	472759.Nhal_1353	3.097e-82	282.0	COG5285@1|root,COG5285@2|Bacteria,1N31I@1224|Proteobacteria,1SDAB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	1.14.11.46	ko:K21195	ko00440,map00440	-	R10724	RC01107	ko00000,ko00001,ko01000	-	-	-	PhyH
CMS1_k127_3511835_8	243233.MCA2571	1.332e-102	340.0	COG0731@1|root,COG0731@2|Bacteria,1QDZ2@1224|Proteobacteria,1RYS3@1236|Gammaproteobacteria,1XDY3@135618|Methylococcales	135618|Methylococcales	C	Radical SAM superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
CMS1_k127_3511835_9	519989.ECTPHS_00230	2.187e-97	323.0	COG0209@1|root,COG0209@2|Bacteria,1P4EH@1224|Proteobacteria,1RP1A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	COG0209 Ribonucleotide reductase, alpha subunit	nrdJb	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3511835_0	1033802.SSPSH_001509	0.0	1084.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,1RQUR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdZ	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Intein_splicing,LAGLIDADG_3,Ribonuc_red_lgC,Ribonuc_red_lgN
CMS1_k127_3511835_6	1198232.CYCME_0396	2.126e-133	439.0	COG1538@1|root,COG1538@2|Bacteria,1MYX2@1224|Proteobacteria,1RNX1@1236|Gammaproteobacteria,4608N@72273|Thiotrichales	72273|Thiotrichales	MU	TIGRFAM type I secretion outer membrane protein, TolC family	-	-	-	ko:K12543	-	M00330	-	-	ko00000,ko00002,ko02000,ko02044	1.B.17,3.A.1.109.4	-	-	OEP
CMS1_k127_3511835_27	857087.Metme_1795	1.455e-36	146.0	COG2197@1|root,COG2197@2|Bacteria,1N8MU@1224|Proteobacteria,1RX1I@1236|Gammaproteobacteria,1XGGG@135618|Methylococcales	135618|Methylococcales	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
CMS1_k127_3511835_21	686340.Metal_2567	4.192e-73	251.0	COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,1RNK4@1236|Gammaproteobacteria,1XGIM@135618|Methylococcales	135618|Methylococcales	M	TIGRFAM type I secretion membrane fusion protein, HlyD	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
CMS1_k127_3512499_1	1198232.CYCME_1498	1.502e-127	419.0	2C3QV@1|root,2Z7YP@2|Bacteria,1MXAM@1224|Proteobacteria,1RNIA@1236|Gammaproteobacteria,460MW@72273|Thiotrichales	72273|Thiotrichales	S	Alginate export	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3512499_2	318996.AXAZ01000001_gene4622	1.068e-57	212.0	COG0596@1|root,COG0596@2|Bacteria,1PJSP@1224|Proteobacteria,2U33J@28211|Alphaproteobacteria,3JXQ9@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
CMS1_k127_3512499_5	1127673.GLIP_4226	4.932e-15	78.0	COG1018@1|root,COG1018@2|Bacteria,1MY2Q@1224|Proteobacteria,1RR5A@1236|Gammaproteobacteria,4676H@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	Oxidoreductase FAD-binding domain	-	-	-	ko:K02613,ko:K07140	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FAD_binding_6,FA_desaturase,Fer2,NAD_binding_1
CMS1_k127_3512499_4	438753.AZC_1281	3.496e-18	89.0	COG1018@1|root,COG1600@1|root,COG3255@1|root,COG1018@2|Bacteria,COG1600@2|Bacteria,COG3255@2|Bacteria,1MXS4@1224|Proteobacteria,2U0QU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_16,SCP2
CMS1_k127_3512499_3	261292.Nit79A3_2492	2.251e-34	135.0	COG1733@1|root,COG1733@2|Bacteria,1N414@1224|Proteobacteria,2VV92@28216|Betaproteobacteria,373CB@32003|Nitrosomonadales	28216|Betaproteobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
CMS1_k127_3512499_0	472759.Nhal_3754	4.631e-128	426.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,1RNAZ@1236|Gammaproteobacteria,1WWPS@135613|Chromatiales	135613|Chromatiales	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
CMS1_k127_3512499_6	1304275.C41B8_16374	1.711e-10	62.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,1RMT8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iAPECO1_1312.APECO1_4018,iECABU_c1320.ECABU_c28100,iECP_1309.ECP_2510,iECSF_1327.ECSF_2349,iUTI89_1310.UTI89_C2826,ic_1306.c3027	CBS,IMPDH,NMO
CMS1_k127_3566261_1	156889.Mmc1_1921	1.979e-93	328.0	COG0515@1|root,COG1262@1|root,COG3170@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,COG3170@2|Bacteria,1PJRR@1224|Proteobacteria,2U625@28211|Alphaproteobacteria	28211|Alphaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	DUF4189,PG_binding_1,Pkinase,WD40
CMS1_k127_3566261_4	1122603.ATVI01000012_gene1200	1.796e-60	216.0	COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,1RPBN@1236|Gammaproteobacteria,1X36H@135614|Xanthomonadales	135614|Xanthomonadales	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	-	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
CMS1_k127_3566261_0	519989.ECTPHS_03267	6.179e-221	691.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,1RP0W@1236|Gammaproteobacteria,1WWIR@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CMS1_k127_3566261_7	1198232.CYCME_0512	4.761e-27	115.0	COG3160@1|root,COG3160@2|Bacteria	2|Bacteria	K	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase	rsd	GO:0000988,GO:0000989,GO:0003674,GO:0008150,GO:0009889,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141	-	ko:K07740	-	-	-	-	ko00000	-	-	-	Rsd_AlgQ
CMS1_k127_3566261_5	309807.SRU_1567	1.786e-46	172.0	COG0758@1|root,COG0758@2|Bacteria,4P58M@976|Bacteroidetes,1FJHP@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	LU	Putative molybdenum carrier	-	-	-	-	-	-	-	-	-	-	-	-	MoCo_carrier
CMS1_k127_3566261_2	1349767.GJA_2110	1.812e-72	252.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,2VKGA@28216|Betaproteobacteria,477B7@75682|Oxalobacteraceae	28216|Betaproteobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	nosF	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_3566261_6	1469245.JFBG01000027_gene1443	3.53e-39	158.0	COG2165@1|root,COG2165@2|Bacteria,1REMT@1224|Proteobacteria,1SF74@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
CMS1_k127_3566261_3	1198452.Jab_2c02510	3.716e-66	234.0	2EMEM@1|root,33F3F@2|Bacteria,1NK08@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3568834_6	187272.Mlg_0011	1.075e-122	404.0	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,1RNR3@1236|Gammaproteobacteria,1WWSJ@135613|Chromatiales	135613|Chromatiales	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
CMS1_k127_3568834_12	1123368.AUIS01000022_gene1037	8.49e-64	224.0	COG0241@1|root,COG0241@2|Bacteria,1RDGR@1224|Proteobacteria,1S3UD@1236|Gammaproteobacteria,2NBS8@225057|Acidithiobacillales	225057|Acidithiobacillales	E	D,D-heptose 1,7-bisphosphate phosphatase	-	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like
CMS1_k127_3568834_9	323261.Noc_0375	5.51e-79	271.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,1RQYC@1236|Gammaproteobacteria,1WXP3@135613|Chromatiales	135613|Chromatiales	I	PFAM Phospholipid glycerol acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
CMS1_k127_3568834_5	323261.Noc_2574	3.844e-158	504.0	COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,1RP6Q@1236|Gammaproteobacteria,1WW00@135613|Chromatiales	135613|Chromatiales	H	Belongs to the ALAD family	-	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
CMS1_k127_3568834_14	686340.Metal_3625	8.851e-44	166.0	arCOG14922@1|root,32SW8@2|Bacteria,1N0NY@1224|Proteobacteria,1S5XN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Copper resistance protein D	-	-	-	-	-	-	-	-	-	-	-	-	CopD
CMS1_k127_3568834_0	1123368.AUIS01000004_gene116	0.0	1106.0	COG1966@1|root,COG1966@2|Bacteria,1MWF9@1224|Proteobacteria,1RMG4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Carbon starvation protein	cstA	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042594,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:0071944	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
CMS1_k127_3568834_17	1123368.AUIS01000004_gene117	3.414e-15	79.0	COG2879@1|root,COG2879@2|Bacteria,1P8X8@1224|Proteobacteria	1224|Proteobacteria	S	Selenoprotein, putative	-	-	-	-	-	-	-	-	-	-	-	-	Sel_put
CMS1_k127_3568834_19	383372.Rcas_2866	2.116e-05	50.0	COG4974@1|root,COG4974@2|Bacteria,2G7RJ@200795|Chloroflexi	200795|Chloroflexi	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
CMS1_k127_3568834_16	1318628.MARLIPOL_12979	4.971e-18	87.0	2DQ92@1|root,335D5@2|Bacteria,1NG6T@1224|Proteobacteria,1SFWE@1236|Gammaproteobacteria,468WM@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Putative prokaryotic signal transducing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2007
CMS1_k127_3568834_18	634956.Geoth_1914	1.234e-13	73.0	COG1592@1|root,COG1592@2|Bacteria,1W59I@1239|Firmicutes,4I0MS@91061|Bacilli	91061|Bacilli	C	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3568834_8	351348.Maqu_3005	3.679e-80	271.0	COG0346@1|root,COG0346@2|Bacteria,1RCYX@1224|Proteobacteria,1RP3M@1236|Gammaproteobacteria,466Y7@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Lactoylglutathione lyase	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
CMS1_k127_3568834_2	1123279.ATUS01000001_gene2747	3.231e-201	636.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,1RMCK@1236|Gammaproteobacteria,1J4KP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains	glnG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
CMS1_k127_3568834_7	713586.KB900536_gene2055	3.021e-87	300.0	COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,1RN15@1236|Gammaproteobacteria,1WWFQ@135613|Chromatiales	135613|Chromatiales	T	signal transduction histidine kinase	-	-	2.7.13.3	ko:K07708	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4
CMS1_k127_3568834_15	1230343.CANP01000004_gene198	6.868e-19	93.0	2E42P@1|root,32YZ5@2|Bacteria,1N868@1224|Proteobacteria,1SCUM@1236|Gammaproteobacteria,1JEK9@118969|Legionellales	118969|Legionellales	S	Domain of unknown function (DUF4124)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124
CMS1_k127_3568834_1	765912.Thimo_3682	3.007e-245	764.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,1RMD1@1236|Gammaproteobacteria,1WVZ2@135613|Chromatiales	135613|Chromatiales	E	TIGRFAM glutamine synthetase, type I	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
CMS1_k127_3568834_11	243233.MCA2592	1.013e-69	244.0	COG0500@1|root,COG2226@2|Bacteria,1RDI3@1224|Proteobacteria,1S423@1236|Gammaproteobacteria,1XFA5@135618|Methylococcales	135618|Methylococcales	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25
CMS1_k127_3568834_3	519989.ECTPHS_11717	1.624e-168	538.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,1RMI2@1236|Gammaproteobacteria,1WVUW@135613|Chromatiales	135613|Chromatiales	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
CMS1_k127_3568834_10	1304275.C41B8_07925	3.56e-76	262.0	COG0400@1|root,COG0400@2|Bacteria,1RA02@1224|Proteobacteria,1S24F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Carboxylesterase	estB	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
CMS1_k127_3568834_4	765912.Thimo_2084	7.381e-165	528.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,1RMWA@1236|Gammaproteobacteria,1WWMG@135613|Chromatiales	135613|Chromatiales	L	DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA	rhlB	-	3.6.4.13	ko:K03732	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03019	-	-	-	DEAD,Helicase_C
CMS1_k127_3568834_13	765913.ThidrDRAFT_1568	4.666e-46	168.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,1S5WR@1236|Gammaproteobacteria,1WY87@135613|Chromatiales	135613|Chromatiales	O	Belongs to the thioredoxin family	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
CMS1_k127_3601368_2	754476.Q7A_565	5.654e-161	517.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,1RMW3@1236|Gammaproteobacteria,45ZW2@72273|Thiotrichales	72273|Thiotrichales	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
CMS1_k127_3601368_3	713586.KB900536_gene1317	8.046e-144	460.0	COG3588@1|root,COG3588@2|Bacteria,1MVFK@1224|Proteobacteria,1RQ57@1236|Gammaproteobacteria,1WZYG@135613|Chromatiales	135613|Chromatiales	G	Fructose-bisphosphate aldolase class-I	-	-	4.1.2.13	ko:K01623	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000,ko03036,ko04131,ko04147	-	-	-	Glycolytic
CMS1_k127_3601368_10	713586.KB900536_gene1317	1.036e-14	74.0	COG3588@1|root,COG3588@2|Bacteria,1MVFK@1224|Proteobacteria,1RQ57@1236|Gammaproteobacteria,1WZYG@135613|Chromatiales	135613|Chromatiales	G	Fructose-bisphosphate aldolase class-I	-	-	4.1.2.13	ko:K01623	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000,ko03036,ko04131,ko04147	-	-	-	Glycolytic
CMS1_k127_3601368_5	1123257.AUFV01000008_gene678	4.536e-114	380.0	COG0628@1|root,COG0628@2|Bacteria,1MW34@1224|Proteobacteria,1RPNK@1236|Gammaproteobacteria,1X4WP@135614|Xanthomonadales	135614|Xanthomonadales	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
CMS1_k127_3601368_1	686340.Metal_2933	3.683e-214	675.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,1RMKV@1236|Gammaproteobacteria,1XE0I@135618|Methylococcales	135618|Methylococcales	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
CMS1_k127_3601368_9	572477.Alvin_0086	1.428e-37	145.0	COG0537@1|root,COG0537@2|Bacteria,1MZVD@1224|Proteobacteria,1S9D9@1236|Gammaproteobacteria,1WZD5@135613|Chromatiales	135613|Chromatiales	FG	PFAM Histidine triad (HIT) protein	-	-	-	-	-	-	-	-	-	-	-	-	HIT
CMS1_k127_3601368_7	1207063.P24_07206	3.202e-83	282.0	COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,2TSJG@28211|Alphaproteobacteria,2JRGA@204441|Rhodospirillales	204441|Rhodospirillales	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
CMS1_k127_3601368_8	1121440.AUMA01000016_gene193	1.502e-65	230.0	COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,43ADI@68525|delta/epsilon subdivisions,2WPU6@28221|Deltaproteobacteria,2MB6H@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Reversible hydration of carbon dioxide	cynT	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
CMS1_k127_3601368_4	187272.Mlg_2257	4.634e-132	427.0	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,1RNNY@1236|Gammaproteobacteria,1WVZH@135613|Chromatiales	135613|Chromatiales	F	SAICAR synthetase	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
CMS1_k127_3601368_6	1122197.ATWI01000011_gene256	1.593e-109	361.0	COG1586@1|root,COG1586@2|Bacteria,1MXPT@1224|Proteobacteria,1RQSX@1236|Gammaproteobacteria,465SJ@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine	speD	GO:0003674,GO:0003824,GO:0004014,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576	4.1.1.50	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	M00034,M00133	R00178	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	iPC815.YPO3412,iSDY_1059.SDY_0027	AdoMet_dc
CMS1_k127_3601368_0	596151.DesfrDRAFT_3108	4.373e-228	714.0	COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,42MAX@68525|delta/epsilon subdivisions,2WJ5B@28221|Deltaproteobacteria,2M7XR@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	PFAM Glutamyl glutaminyl-tRNA synthetase, class Ic, catalytic	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	GatB_Yqey,tRNA-synt_1c,tRNA-synt_1c_C
CMS1_k127_3603982_24	314285.KT71_18781	2.247e-20	96.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,1RP3U@1236|Gammaproteobacteria,1J9FN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Resolvase, N terminal domain	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
CMS1_k127_3603982_17	870187.Thini_1596	1.377e-61	219.0	COG3658@1|root,COG3658@2|Bacteria,1RIG7@1224|Proteobacteria,1S4KI@1236|Gammaproteobacteria,463S5@72273|Thiotrichales	72273|Thiotrichales	C	Prokaryotic cytochrome b561	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
CMS1_k127_3603982_13	1122604.JONR01000007_gene2802	4.578e-100	343.0	COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria,1X58A@135614|Xanthomonadales	135614|Xanthomonadales	M	Bacterial periplasmic substrate-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_3,SLT
CMS1_k127_3603982_8	1163617.SCD_n02729	6.085e-128	418.0	COG2334@1|root,COG2334@2|Bacteria,1MU2Q@1224|Proteobacteria,2VI9A@28216|Betaproteobacteria	28216|Betaproteobacteria	F	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response	srkA	-	-	-	-	-	-	-	-	-	-	-	APH
CMS1_k127_3603982_1	1122201.AUAZ01000036_gene1217	8.573e-265	828.0	COG1132@1|root,COG1132@2|Bacteria,1N1Z8@1224|Proteobacteria,1RPVC@1236|Gammaproteobacteria,4664T@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	ABC transporter transmembrane region	ygaD	-	-	ko:K06147,ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
CMS1_k127_3603982_14	335283.Neut_1019	1.898e-98	336.0	COG2200@1|root,COG3279@1|root,COG2200@2|Bacteria,COG3279@2|Bacteria,1N299@1224|Proteobacteria,2VKSH@28216|Betaproteobacteria,372CK@32003|Nitrosomonadales	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,Response_reg
CMS1_k127_3603982_25	323261.Noc_0317	1.545e-19	97.0	COG3159@1|root,COG3159@2|Bacteria,1R4BP@1224|Proteobacteria,1S9SC@1236|Gammaproteobacteria,1WY2X@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function, DUF484	-	-	-	ko:K09921	-	-	-	-	ko00000	-	-	-	DUF484
CMS1_k127_3603982_20	187272.Mlg_0812	1.35e-37	149.0	COG4659@1|root,COG4659@2|Bacteria,1RDEP@1224|Proteobacteria,1RPAD@1236|Gammaproteobacteria,1WVYN@135613|Chromatiales	135613|Chromatiales	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
CMS1_k127_3603982_12	323261.Noc_1172	4.705e-106	355.0	COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,1RMEU@1236|Gammaproteobacteria,1WX3R@135613|Chromatiales	135613|Chromatiales	C	Part of a membrane complex involved in electron transport	rnfD	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
CMS1_k127_3603982_6	472759.Nhal_2748	4.201e-154	501.0	COG4656@1|root,COG4656@2|Bacteria,1QTUI@1224|Proteobacteria,1RMIM@1236|Gammaproteobacteria,1WWSK@135613|Chromatiales	135613|Chromatiales	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4_10,Fer4_7,Fer4_8,RnfC_N,SLBB
CMS1_k127_3603982_18	497321.C664_14194	5.616e-59	209.0	COG2878@1|root,COG2878@2|Bacteria,1MUWU@1224|Proteobacteria,2VN5I@28216|Betaproteobacteria,2KVNK@206389|Rhodocyclales	206389|Rhodocyclales	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4_21
CMS1_k127_3603982_22	713586.KB900536_gene2723	1.981e-29	124.0	COG4657@1|root,COG4657@2|Bacteria,1MU8X@1224|Proteobacteria,1RQDN@1236|Gammaproteobacteria,1WX8K@135613|Chromatiales	135613|Chromatiales	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
CMS1_k127_3603982_0	582744.Msip34_1098	0.0	1003.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,2VH19@28216|Betaproteobacteria,2KKUH@206350|Nitrosomonadales	206350|Nitrosomonadales	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1g,tRNA_bind
CMS1_k127_3603982_7	396588.Tgr7_2621	4.292e-153	491.0	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,1RMJF@1236|Gammaproteobacteria,1WX3A@135613|Chromatiales	135613|Chromatiales	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
CMS1_k127_3603982_21	330214.NIDE4309	5.314e-36	139.0	COG0399@1|root,COG0399@2|Bacteria	2|Bacteria	E	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	23S_rRNA_IVP,DegT_DnrJ_EryC1
CMS1_k127_3603982_11	1235457.C404_16470	1.838e-109	356.0	COG0717@1|root,COG0717@2|Bacteria,1MV2J@1224|Proteobacteria,2VIJ0@28216|Betaproteobacteria,1K38F@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Belongs to the dCTP deaminase family	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
CMS1_k127_3603982_23	1122604.JONR01000030_gene1322	7.516e-22	96.0	COG3905@1|root,COG3905@2|Bacteria,1N7D2@1224|Proteobacteria,1SCP8@1236|Gammaproteobacteria,1X919@135614|Xanthomonadales	135614|Xanthomonadales	K	copG family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3603982_3	1163617.SCD_n02022	1.067e-229	730.0	COG0651@1|root,COG0651@2|Bacteria,1MXRW@1224|Proteobacteria,2VMAN@28216|Betaproteobacteria	28216|Betaproteobacteria	CP	NADH ubiquinone plastoquinone (Complex I)	hyfB	-	-	-	-	-	-	-	-	-	-	-	Proton_antipo_M
CMS1_k127_3603982_9	1163617.SCD_n02023	8.738e-126	412.0	COG0650@1|root,COG0650@2|Bacteria,1MXV5@1224|Proteobacteria,2VKBD@28216|Betaproteobacteria	28216|Betaproteobacteria	C	NADH dehydrogenase	hyfD	-	-	-	-	-	-	-	-	-	-	-	NADHdh
CMS1_k127_3603982_15	1163617.SCD_n02024	1.554e-88	297.0	COG4237@1|root,COG4237@2|Bacteria,1NAT8@1224|Proteobacteria,2VJTI@28216|Betaproteobacteria	28216|Betaproteobacteria	C	hydrogenase 4 membrane	hyfE	-	-	ko:K12140	-	-	-	-	ko00000,ko01000	-	-	-	-
CMS1_k127_3603982_2	1163617.SCD_n02025	6.167e-240	748.0	COG0651@1|root,COG0651@2|Bacteria,1MVBA@1224|Proteobacteria,2VKBR@28216|Betaproteobacteria	28216|Betaproteobacteria	CP	NADH Ubiquinone plastoquinone (Complex I)	hyfF	-	-	ko:K12141	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M
CMS1_k127_3603982_4	1163617.SCD_n02026	3.014e-204	647.0	COG3261@1|root,COG3262@1|root,COG3261@2|Bacteria,COG3262@2|Bacteria,1QUBF@1224|Proteobacteria,2VJ0R@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Respiratory-chain NADH dehydrogenase, 49 Kd subunit	hyfG	-	-	-	-	-	-	-	-	-	-	-	Complex1_30kDa,Complex1_49kDa,NiFeSe_Hases
CMS1_k127_3603982_16	1163617.SCD_n02027	2.637e-77	263.0	COG3260@1|root,COG3260@2|Bacteria,1QUBE@1224|Proteobacteria,2VP8A@28216|Betaproteobacteria	28216|Betaproteobacteria	C	NADH ubiquinone oxidoreductase 20 kDa subunit	hyfI	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q6
CMS1_k127_3603982_5	323848.Nmul_A2313	3.089e-188	598.0	COG0007@1|root,COG1648@1|root,COG0007@2|Bacteria,COG1648@2|Bacteria,1MUI0@1224|Proteobacteria,2VICS@28216|Betaproteobacteria,371WH@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme	cysG	-	1.3.1.76,2.1.1.107,4.99.1.4	ko:K02302,ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03194,R03947	RC00003,RC00871,RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase
CMS1_k127_3603982_27	686578.AFFX01000004_gene3596	5.575e-10	69.0	COG3056@1|root,COG3056@2|Bacteria,1N9MP@1224|Proteobacteria,1SCR5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Uncharacterized lipoprotein	IV02_13505	-	-	ko:K07286	-	-	-	-	ko00000	-	-	-	Lipoprotein_16
CMS1_k127_3603982_10	767817.Desgi_0931	6.579e-113	382.0	COG0471@1|root,COG0471@2|Bacteria,1TSP2@1239|Firmicutes,24DU3@186801|Clostridia,26769@186807|Peptococcaceae	186801|Clostridia	P	Similarity to COG0471 Di- and tricarboxylate transporters(Evalue	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
CMS1_k127_3620840_7	1207063.P24_17897	4.796e-75	258.0	COG0438@1|root,COG0438@2|Bacteria,1NJ19@1224|Proteobacteria,2TRT4@28211|Alphaproteobacteria,2JPS9@204441|Rhodospirillales	204441|Rhodospirillales	M	Gkycosyl transferase family 4 group	expC	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_3,Glycos_transf_1
CMS1_k127_3620840_2	414684.RC1_0358	4.748e-102	349.0	COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,2TSP0@28211|Alphaproteobacteria,2JPY8@204441|Rhodospirillales	204441|Rhodospirillales	M	COG0845 Membrane-fusion protein	-	-	-	ko:K16300	-	M00571	-	-	ko00000,ko00002,ko02000,ko02044	8.A.1.3.3	-	-	Biotin_lipoyl_2,HlyD,HlyD_3
CMS1_k127_3620840_1	414684.RC1_0357	5.495e-172	557.0	COG4618@1|root,COG4618@2|Bacteria,1NTI5@1224|Proteobacteria,2TR17@28211|Alphaproteobacteria,2JPRW@204441|Rhodospirillales	204441|Rhodospirillales	V	COG4618 ABC-type protease lipase transport system, ATPase and permease components	-	-	-	ko:K16299	ko02010,map02010	M00571	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1.110.10	-	-	ABC_membrane,ABC_tran
CMS1_k127_3620840_13	331869.BAL199_07463	2.738e-41	164.0	COG4714@1|root,COG4714@2|Bacteria	2|Bacteria	EGP	membrane-anchored protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
CMS1_k127_3620840_5	1121033.AUCF01000009_gene1020	1.791e-82	286.0	COG0739@1|root,COG0739@2|Bacteria,1PVZJ@1224|Proteobacteria,2TRAB@28211|Alphaproteobacteria,2JS4X@204441|Rhodospirillales	204441|Rhodospirillales	M	COG0739 Membrane proteins related to metalloendopeptidases	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CMS1_k127_3620840_9	388467.A19Y_1638	5.613e-67	235.0	COG0457@1|root,COG0457@2|Bacteria,1G6S8@1117|Cyanobacteria,1HGG7@1150|Oscillatoriales	1117|Cyanobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_2
CMS1_k127_3620840_11	272942.RCAP_rcc02216	2.333e-48	184.0	2DKVZ@1|root,30IFS@2|Bacteria,1RCZN@1224|Proteobacteria	1224|Proteobacteria	S	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1
CMS1_k127_3620840_6	696747.NIES39_J05240	5.165e-79	274.0	COG0438@1|root,COG0438@2|Bacteria,1G2PH@1117|Cyanobacteria,1HAF4@1150|Oscillatoriales	1117|Cyanobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3620840_17	314285.KT71_19799	9.569e-24	111.0	2EI8J@1|root,33BZX@2|Bacteria,1P68C@1224|Proteobacteria,1SUE6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3620840_16	314285.KT71_19794	1.441e-28	124.0	COG4122@1|root,COG4122@2|Bacteria,1NDFA@1224|Proteobacteria,1SFFH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_2
CMS1_k127_3620840_15	867845.KI911784_gene1214	2.466e-30	130.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_tranf_2_3,Glyco_trans_1_4,Glyco_transf_17,Glyco_transf_4,Stealth_CR1,Stealth_CR2,Stealth_CR3,Sulfotransfer_1
CMS1_k127_3620840_3	450851.PHZ_c0493	1.651e-101	341.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	ko:K22227	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
CMS1_k127_3620840_8	1198232.CYCME_0446	2.848e-74	259.0	COG1134@1|root,COG1134@2|Bacteria,1MWWC@1224|Proteobacteria,1S2FR@1236|Gammaproteobacteria,460IR@72273|Thiotrichales	72273|Thiotrichales	GM	ABC transporter	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran
CMS1_k127_3620840_10	96561.Dole_1284	1.088e-61	222.0	COG1682@1|root,COG1682@2|Bacteria,1N0X3@1224|Proteobacteria,42SZT@68525|delta/epsilon subdivisions,2WPXG@28221|Deltaproteobacteria,2MKBV@213118|Desulfobacterales	28221|Deltaproteobacteria	GM	PFAM ABC-2 type transporter	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
CMS1_k127_3620840_4	118161.KB235922_gene1650	7.7e-90	302.0	COG0500@1|root,COG0500@2|Bacteria,1GQT2@1117|Cyanobacteria,3VNIA@52604|Pleurocapsales	1117|Cyanobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS1_k127_3620840_12	41431.PCC8801_0048	7.71e-42	165.0	COG0457@1|root,COG0457@2|Bacteria,1G7C5@1117|Cyanobacteria,3KIQY@43988|Cyanothece	1117|Cyanobacteria	S	Putative capsular polysaccharide synthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	NKWYS
CMS1_k127_3620840_14	1282356.H045_13150	1.994e-33	151.0	COG1216@1|root,COG3754@1|root,COG1216@2|Bacteria,COG3754@2|Bacteria,1MX5Z@1224|Proteobacteria,1RMDY@1236|Gammaproteobacteria,1YNG9@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_tranf_2_3,Glyco_trans_1_2,Glycos_transf_2,RgpF
CMS1_k127_3620840_0	1121405.dsmv_2647	1.197e-199	658.0	COG0438@1|root,COG1216@1|root,COG3551@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,COG3551@2|Bacteria,1PFY4@1224|Proteobacteria,439ZE@68525|delta/epsilon subdivisions,2X1Z4@28221|Deltaproteobacteria,2MNSP@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3620840_18	1049564.TevJSym_at00310	1.109e-14	77.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,1RYF4@1236|Gammaproteobacteria,1J8MZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	GM	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_2
CMS1_k127_3631652_2	1288494.EBAPG3_20660	1.607e-263	830.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria,371RW@32003|Nitrosomonadales	28216|Betaproteobacteria	P	TIGRFAM ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter	-	-	3.6.3.9	ko:K01539	ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978	-	-	-	ko00000,ko00001,ko01000,ko04147	3.A.3.1	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
CMS1_k127_3631652_9	472759.Nhal_1778	3.825e-124	417.0	COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,1RN6R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	-	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
CMS1_k127_3631652_1	472759.Nhal_1845	0.0	1050.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,1RMYC@1236|Gammaproteobacteria,1WX32@135613|Chromatiales	135613|Chromatiales	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3,LysM
CMS1_k127_3631652_11	1492922.GY26_06930	1.004e-82	280.0	COG0847@1|root,COG0847@2|Bacteria,1MUPK@1224|Proteobacteria,1RMMH@1236|Gammaproteobacteria,1J5U7@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis	rnt	GO:0000287,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0031123,GO:0034470,GO:0034641,GO:0034660,GO:0042780,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360	-	ko:K03683	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_T
CMS1_k127_3631652_5	1158762.KB898040_gene1557	3.293e-151	486.0	COG0418@1|root,COG0418@2|Bacteria,1MUYP@1224|Proteobacteria,1RNEN@1236|Gammaproteobacteria,1WXAJ@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
CMS1_k127_3631652_18	266117.Rxyl_0955	7.85e-48	179.0	COG2095@1|root,COG2095@2|Bacteria,2GMCM@201174|Actinobacteria	201174|Actinobacteria	U	UPF0056 membrane protein	-	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
CMS1_k127_3631652_7	765911.Thivi_3476	8.959e-148	475.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,1RNXH@1236|Gammaproteobacteria,1WW4N@135613|Chromatiales	135613|Chromatiales	C	PFAM aldo keto reductase	tas	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS1_k127_3631652_3	1415780.JPOG01000001_gene1224	1.803e-186	592.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,1RN93@1236|Gammaproteobacteria,1X3E0@135614|Xanthomonadales	135614|Xanthomonadales	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ASL_C,Lyase_1
CMS1_k127_3631652_10	69328.PVLB_15000	8.331e-94	321.0	COG2850@1|root,COG2850@2|Bacteria,1MW30@1224|Proteobacteria,1RN2Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Cupin 4 family protein	ycfD	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0016491,GO:0016705,GO:0016706,GO:0018193,GO:0018195,GO:0019538,GO:0030961,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046914,GO:0051213,GO:0055114,GO:0071704,GO:1901564	1.14.11.47	ko:K18850	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Cupin_4
CMS1_k127_3631652_21	1198232.CYCME_1255	3.479e-11	70.0	COG2153@1|root,COG2153@2|Bacteria,1N7TN@1224|Proteobacteria,1SCI6@1236|Gammaproteobacteria,461HJ@72273|Thiotrichales	72273|Thiotrichales	S	protein acetylation	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3631652_17	640081.Dsui_2222	2.679e-48	184.0	COG4796@1|root,COG4796@2|Bacteria,1RCNA@1224|Proteobacteria,2WGZA@28216|Betaproteobacteria,2KWAH@206389|Rhodocyclales	206389|Rhodocyclales	U	Bacterial type II and III secretion system protein	-	-	-	-	-	-	-	-	-	-	-	-	Secretin
CMS1_k127_3631652_0	1123368.AUIS01000007_gene2749	0.0	1553.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,2NBUJ@225057|Acidithiobacillales	225057|Acidithiobacillales	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
CMS1_k127_3631652_8	518766.Rmar_0538	1.818e-130	425.0	COG2041@1|root,COG2041@2|Bacteria,4NK0M@976|Bacteroidetes	976|Bacteroidetes	S	Oxidoreductase molybdopterin binding domain	-	-	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_molyb
CMS1_k127_3631652_16	1123392.AQWL01000002_gene1981	2.042e-61	217.0	COG2717@1|root,COG2717@2|Bacteria,1RDUP@1224|Proteobacteria,2VRBQ@28216|Betaproteobacteria,1KSU5@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Ferric reductase like transmembrane component	-	-	-	-	-	-	-	-	-	-	-	-	Ferric_reduct
CMS1_k127_3631652_19	323261.Noc_1906	2.367e-37	147.0	COG2840@1|root,COG2840@2|Bacteria,1RH34@1224|Proteobacteria,1S6B5@1236|Gammaproteobacteria,1X2FV@135613|Chromatiales	135613|Chromatiales	S	Smr protein	-	-	-	-	-	-	-	-	-	-	-	-	Smr
CMS1_k127_3631652_6	1123368.AUIS01000010_gene2326	8.829e-151	507.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K10715,ko:K20974	ko02020,ko02024,ko02025,map02020,map02024,map02025	M00517,M00820	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,GAF_2,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
CMS1_k127_3631652_13	452638.Pnec_0028	1.545e-71	255.0	COG3239@1|root,COG3239@2|Bacteria,1MY4I@1224|Proteobacteria,2VKQE@28216|Betaproteobacteria,1K354@119060|Burkholderiaceae	28216|Betaproteobacteria	I	fatty acid desaturase	-	-	1.14.19.23,1.14.19.45	ko:K10255	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
CMS1_k127_3631652_14	580332.Slit_1288	2.658e-70	248.0	COG1024@1|root,COG1024@2|Bacteria,1MUD7@1224|Proteobacteria,2VQ37@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Pfam Enoyl-CoA hydratase isomerase	-	-	-	ko:K13816	ko02020,ko02024,map02020,map02024	-	-	-	ko00000,ko00001	-	-	-	ECH_1
CMS1_k127_3631652_15	396588.Tgr7_1187	3.06e-62	218.0	COG0245@1|root,COG0245@2|Bacteria,1MVHA@1224|Proteobacteria,1S3RQ@1236|Gammaproteobacteria,1WY23@135613|Chromatiales	135613|Chromatiales	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	4.6.1.12	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
CMS1_k127_3631652_12	572477.Alvin_0393	2.071e-73	256.0	COG1211@1|root,COG1211@2|Bacteria,1MY3B@1224|Proteobacteria,1S21S@1236|Gammaproteobacteria,1WXHT@135613|Chromatiales	135613|Chromatiales	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
CMS1_k127_3631652_20	1249627.D779_0408	1.467e-21	97.0	COG2919@1|root,COG2919@2|Bacteria,1N7AA@1224|Proteobacteria,1SD8H@1236|Gammaproteobacteria,1WZ9J@135613|Chromatiales	135613|Chromatiales	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	ftsB	-	-	ko:K05589	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
CMS1_k127_3631652_4	395493.BegalDRAFT_1820	2.955e-164	522.0	COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,1RNQA@1236|Gammaproteobacteria,46068@72273|Thiotrichales	72273|Thiotrichales	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
CMS1_k127_3648056_4	1163617.SCD_n00407	0.0004736	42.0	COG0642@1|root,COG2205@2|Bacteria,1MUAK@1224|Proteobacteria,2VJ6W@28216|Betaproteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07638	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
CMS1_k127_3648056_1	498211.CJA_3374	9.66e-24	104.0	COG3169@1|root,COG3169@2|Bacteria,1RHBQ@1224|Proteobacteria,1S7UR@1236|Gammaproteobacteria,1FHHJ@10|Cellvibrio	1236|Gammaproteobacteria	S	Putative member of DMT superfamily (DUF486)	-	-	-	ko:K09922	-	-	-	-	ko00000	-	-	-	DMT_6
CMS1_k127_3648056_3	706587.Desti_5375	2.772e-06	51.0	COG3169@1|root,COG3169@2|Bacteria,1RHBQ@1224|Proteobacteria,42SES@68525|delta/epsilon subdivisions,2WQ9T@28221|Deltaproteobacteria,2MRZE@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Putative member of DMT superfamily (DUF486)	-	-	-	ko:K09922	-	-	-	-	ko00000	-	-	-	DMT_6
CMS1_k127_3648056_0	41431.PCC8801_3794	1.195e-126	427.0	2EZGF@1|root,33SMM@2|Bacteria,1GKV9@1117|Cyanobacteria,3KG2G@43988|Cyanothece	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3648056_2	1121918.ARWE01000001_gene3021	2.715e-12	79.0	2C1AX@1|root,33GUX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3666691_4	1267533.KB906738_gene2382	6.255e-106	355.0	COG1237@1|root,COG1237@2|Bacteria,3Y8MA@57723|Acidobacteria	57723|Acidobacteria	S	Metallo-beta-lactamase superfamily	-	-	2.5.1.105	ko:K06897	ko00790,map00790	-	R10339	RC00121	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
CMS1_k127_3666691_8	1124780.ANNU01000046_gene2239	0.0001746	44.0	COG1525@1|root,COG1525@2|Bacteria	2|Bacteria	L	nuclease	exoI	-	-	-	-	-	-	-	-	-	-	-	Excalibur,SNase
CMS1_k127_3666691_3	439235.Dalk_2094	2.695e-138	466.0	COG0664@1|root,COG1752@1|root,COG0664@2|Bacteria,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,42RSN@68525|delta/epsilon subdivisions,2WNDI@28221|Deltaproteobacteria,2MPUY@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin,cNMP_binding
CMS1_k127_3666691_2	1278073.MYSTI_00632	1.687e-149	487.0	COG1012@1|root,COG1012@2|Bacteria,1MVGW@1224|Proteobacteria,42N65@68525|delta/epsilon subdivisions,2WJ98@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3,1.2.1.68	ko:K00128,ko:K00154	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS1_k127_3666691_0	745411.B3C1_09682	0.0	1146.0	COG2010@1|root,COG2010@2|Bacteria,1R58S@1224|Proteobacteria,1RZ9B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_3666691_7	1026882.MAMP_01454	1.774e-13	77.0	COG2010@1|root,COG2010@2|Bacteria,1NBQJ@1224|Proteobacteria,1SIJ9@1236|Gammaproteobacteria,4639T@72273|Thiotrichales	72273|Thiotrichales	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CMS1_k127_3666691_5	595593.JREV01000045_gene674	1.618e-82	285.0	COG0300@1|root,COG0300@2|Bacteria,2IAR1@201174|Actinobacteria,1W951@1268|Micrococcaceae	201174|Actinobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.105	ko:K07124,ko:K15734	ko00830,map00830	-	R02124	RC00649	ko00000,ko00001,ko01000	-	-	-	adh_short
CMS1_k127_3666691_1	29581.BW37_02812	2.345e-221	738.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,2WGK9@28216|Betaproteobacteria,4791Y@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,HAMP,HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_9,Response_reg
CMS1_k127_3723719_8	626887.J057_10366	3.372e-34	134.0	COG0644@1|root,COG0644@2|Bacteria,1MXQY@1224|Proteobacteria,1SEJ8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	geranylgeranyl reductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
CMS1_k127_3723719_3	713586.KB900536_gene2819	2.89e-138	452.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,1S1KY@1236|Gammaproteobacteria,1X28H@135613|Chromatiales	135613|Chromatiales	M	Mycolic acid cyclopropane synthetase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
CMS1_k127_3723719_6	909663.KI867149_gene3210	1.091e-54	196.0	COG2606@1|root,COG2606@2|Bacteria,1N10Y@1224|Proteobacteria,43ACP@68525|delta/epsilon subdivisions,2WW7Y@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Aminoacyl-tRNA editing domain	-	-	-	ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
CMS1_k127_3723719_9	887062.HGR_08954	9.019e-24	107.0	COG2010@1|root,COG2010@2|Bacteria,1PZ21@1224|Proteobacteria,2W347@28216|Betaproteobacteria,4AI4W@80864|Comamonadaceae	28216|Betaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
CMS1_k127_3723719_1	519989.ECTPHS_11822	4.743e-147	474.0	COG0232@1|root,COG0232@2|Bacteria,1MVQ2@1224|Proteobacteria,1RPVJ@1236|Gammaproteobacteria,1X0VD@135613|Chromatiales	135613|Chromatiales	F	Belongs to the dGTPase family. Type 2 subfamily	-	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
CMS1_k127_3723719_2	765912.Thimo_0089	1.106e-143	464.0	COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,1RN4I@1236|Gammaproteobacteria,1WWZW@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
CMS1_k127_3723719_5	1502852.FG94_01382	3.687e-55	198.0	COG0337@1|root,COG0703@1|root,COG0337@2|Bacteria,COG0703@2|Bacteria,1MUBK@1224|Proteobacteria,2VHXR@28216|Betaproteobacteria,4725Y@75682|Oxalobacteraceae	28216|Betaproteobacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
CMS1_k127_3723719_0	472759.Nhal_3887	6.292e-217	694.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,1RN3Z@1236|Gammaproteobacteria,1WWYN@135613|Chromatiales	135613|Chromatiales	U	type IV pilus secretin PilQ	-	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
CMS1_k127_3723719_7	572477.Alvin_3057	5.289e-36	143.0	COG3168@1|root,COG3168@2|Bacteria,1RI6V@1224|Proteobacteria,1S6VJ@1236|Gammaproteobacteria,1WYAC@135613|Chromatiales	135613|Chromatiales	NU	pilus assembly protein PilP	-	-	-	ko:K02665	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilP
CMS1_k127_3723719_4	1049564.TevJSym_bb00160	9.783e-58	208.0	COG3167@1|root,COG3167@2|Bacteria,1RBGW@1224|Proteobacteria,1S3XQ@1236|Gammaproteobacteria,1J6DF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	NU	Pilus assembly protein, PilO	pilO	-	-	ko:K02664	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilO
CMS1_k127_3723719_10	765910.MARPU_16495	0.0001665	45.0	COG3166@1|root,COG3166@2|Bacteria,1RF1S@1224|Proteobacteria,1S3S0@1236|Gammaproteobacteria,1WY4Z@135613|Chromatiales	135613|Chromatiales	NU	PFAM Fimbrial assembly	-	-	-	ko:K02663	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilN
CMS1_k127_3813679_18	398767.Glov_1169	6.145e-19	98.0	COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,42MAT@68525|delta/epsilon subdivisions,2WKY9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Peptidase_C14
CMS1_k127_3813679_5	713586.KB900536_gene424	1.1e-129	422.0	COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,1RMKW@1236|Gammaproteobacteria,1WW5P@135613|Chromatiales	135613|Chromatiales	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
CMS1_k127_3813679_3	472759.Nhal_2357	9.828e-169	537.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,1RMY3@1236|Gammaproteobacteria,1WWQ8@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
CMS1_k127_3813679_16	395493.BegalDRAFT_3486	3.706e-35	137.0	COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,1S9NV@1236|Gammaproteobacteria,4613V@72273|Thiotrichales	72273|Thiotrichales	U	Preprotein translocase, YajC subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
CMS1_k127_3813679_0	472759.Nhal_2359	8.697e-224	709.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,1RMIQ@1236|Gammaproteobacteria,1WX1G@135613|Chromatiales	135613|Chromatiales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD-TM1,SecD_SecF,Sec_GG
CMS1_k127_3813679_4	365046.Rta_36960	1.834e-130	423.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,2VHZG@28216|Betaproteobacteria,4A9SD@80864|Comamonadaceae	28216|Betaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
CMS1_k127_3813679_10	395493.BegalDRAFT_1488	1.088e-90	312.0	COG0111@1|root,COG0111@2|Bacteria,1N5TD@1224|Proteobacteria,1RMFW@1236|Gammaproteobacteria,460NT@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate	pdxB	-	1.1.1.290	ko:K03473	ko00750,ko01100,map00750,map01100	M00124	R04210	RC00084	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C,DUF3410
CMS1_k127_3813679_12	382464.ABSI01000011_gene2992	1.275e-70	245.0	COG0299@1|root,COG0299@2|Bacteria,46SS6@74201|Verrucomicrobia,2IU5Z@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	-	-	-	-	-	-	-	-	-	-	-	-	Formyl_trans_N
CMS1_k127_3813679_7	243233.MCA1969	2.135e-120	392.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,1RMCJ@1236|Gammaproteobacteria,1XET4@135618|Methylococcales	135618|Methylococcales	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
CMS1_k127_3813679_8	472759.Nhal_0342	2.579e-114	374.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,1RM9H@1236|Gammaproteobacteria,1WWID@135613|Chromatiales	135613|Chromatiales	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
CMS1_k127_3813679_13	472759.Nhal_0343	1.338e-49	181.0	COG1463@1|root,COG1463@2|Bacteria,1NCUG@1224|Proteobacteria,1RQ0Y@1236|Gammaproteobacteria,1WXYG@135613|Chromatiales	135613|Chromatiales	Q	PFAM Mammalian cell entry related domain protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
CMS1_k127_3813679_14	105559.Nwat_0306	1.242e-45	173.0	COG2854@1|root,COG2854@2|Bacteria,1NKFA@1224|Proteobacteria,1RNJW@1236|Gammaproteobacteria,1WXHN@135613|Chromatiales	135613|Chromatiales	Q	PFAM toluene tolerance	-	-	-	ko:K07323	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	MlaC
CMS1_k127_3813679_19	1283300.ATXB01000001_gene733	9.285e-13	72.0	COG3113@1|root,COG3113@2|Bacteria,1NGIE@1224|Proteobacteria,1SGH6@1236|Gammaproteobacteria,1XFQI@135618|Methylococcales	135618|Methylococcales	S	STAS domain	-	-	-	ko:K07122	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	STAS_2
CMS1_k127_3813679_17	62928.azo0814	3.317e-20	92.0	COG5007@1|root,COG5007@2|Bacteria,1MZCZ@1224|Proteobacteria,2VU0K@28216|Betaproteobacteria,2KWVP@206389|Rhodocyclales	206389|Rhodocyclales	K	Belongs to the BolA IbaG family	-	-	-	-	-	-	-	-	-	-	-	-	BolA
CMS1_k127_3813679_1	243233.MCA1965	3.55e-200	630.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,1RN91@1236|Gammaproteobacteria,1XE8B@135618|Methylococcales	135618|Methylococcales	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
CMS1_k127_3813679_11	765913.ThidrDRAFT_2347	2.271e-83	282.0	COG0040@1|root,COG0040@2|Bacteria,1MUCY@1224|Proteobacteria,1RNAX@1236|Gammaproteobacteria,1WX3P@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG
CMS1_k127_3813679_2	396588.Tgr7_0745	2.019e-172	553.0	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,1RMZD@1236|Gammaproteobacteria,1WX79@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
CMS1_k127_3813679_6	472759.Nhal_0352	6.259e-124	407.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,1RP4T@1236|Gammaproteobacteria,1WX7G@135613|Chromatiales	135613|Chromatiales	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC2	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS1_k127_3813679_9	396588.Tgr7_0747	3.062e-103	347.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1X0EW@135613|Chromatiales	135613|Chromatiales	O	Trypsin	-	-	-	ko:K04691	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
CMS1_k127_3813679_15	550540.Fbal_3421	3.887e-38	146.0	COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,1RP9H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petA	-	1.10.2.2	ko:K00411	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,UCR_Fe-S_N
CMS1_k127_3930295_14	472759.Nhal_0217	0.0001026	48.0	COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,1RMMF@1236|Gammaproteobacteria,1WWU1@135613|Chromatiales	135613|Chromatiales	S	TamB, inner membrane protein subunit of TAM complex	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
CMS1_k127_3930295_7	857087.Metme_0149	1.396e-53	195.0	COG1651@1|root,COG1651@2|Bacteria,1RGWH@1224|Proteobacteria,1S5WA@1236|Gammaproteobacteria,1XEWA@135618|Methylococcales	135618|Methylococcales	O	Thiol disulfide interchange protein	dsbA	-	-	ko:K03673	ko01503,map01503	M00728	-	-	ko00000,ko00001,ko00002,ko03110	-	-	-	DSBA
CMS1_k127_3930295_5	1123400.KB904754_gene1017	1.008e-61	219.0	COG2863@1|root,COG2863@2|Bacteria,1N2NB@1224|Proteobacteria,1RZFP@1236|Gammaproteobacteria,460ST@72273|Thiotrichales	72273|Thiotrichales	C	PFAM cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
CMS1_k127_3930295_6	1149133.ppKF707_5529	1.013e-54	199.0	COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,1RNJP@1236|Gammaproteobacteria,1YEDQ@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	D	Necessary for normal cell division and for the maintenance of normal septation	engB	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
CMS1_k127_3930295_1	754476.Q7A_70	1.032e-142	467.0	COG4784@1|root,COG4784@2|Bacteria,1QTT7@1224|Proteobacteria,1RSQ1@1236|Gammaproteobacteria,460MY@72273|Thiotrichales	72273|Thiotrichales	S	Zn-dependent protease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
CMS1_k127_3930295_9	765914.ThisiDRAFT_1970	8.932e-42	166.0	COG1525@1|root,COG1525@2|Bacteria,1RKRQ@1224|Proteobacteria,1S7UH@1236|Gammaproteobacteria,1X24P@135613|Chromatiales	135613|Chromatiales	L	Staphylococcal nuclease homologues	-	-	-	-	-	-	-	-	-	-	-	-	SNase
CMS1_k127_3930295_11	1026882.MAMP_00242	6.643e-29	118.0	COG0254@1|root,COG0254@2|Bacteria,1MZ69@1224|Proteobacteria,1SCMH@1236|Gammaproteobacteria,461AF@72273|Thiotrichales	72273|Thiotrichales	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
CMS1_k127_3930295_3	243233.MCA3070	2.03e-102	339.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,1RN4H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Exodeoxyribonuclease III	xthA	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
CMS1_k127_3930295_13	1479237.JMLY01000001_gene2811	1.006e-05	55.0	COG3807@1|root,COG3807@2|Bacteria,1QWZW@1224|Proteobacteria,1T31J@1236|Gammaproteobacteria,467XH@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	SH3 domain protein	ygiM	-	-	ko:K07184	-	-	-	-	ko00000	-	-	-	SH3_3
CMS1_k127_3930295_0	1026882.MAMP_01479	1.965e-292	912.0	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,1RMAH@1236|Gammaproteobacteria,45ZQH@72273|Thiotrichales	72273|Thiotrichales	E	peptidase	-	-	3.4.24.70	ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
CMS1_k127_3930295_8	1234364.AMSF01000021_gene1272	8.851e-44	162.0	COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,1S656@1236|Gammaproteobacteria,1X6DR@135614|Xanthomonadales	135614|Xanthomonadales	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
CMS1_k127_3930295_4	1249627.D779_3936	5.204e-67	234.0	COG2077@1|root,COG2077@2|Bacteria,1RAJ9@1224|Proteobacteria,1S263@1236|Gammaproteobacteria,1WX7S@135613|Chromatiales	135613|Chromatiales	O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides	tpx	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	Redoxin
CMS1_k127_3930295_10	713586.KB900536_gene2605	1.007e-38	150.0	COG0818@1|root,COG0818@2|Bacteria,1MZ3Q@1224|Proteobacteria,1S92I@1236|Gammaproteobacteria,1WYCK@135613|Chromatiales	135613|Chromatiales	M	Recycling of diacylglycerol produced during the turnover of membrane phospholipid	-	-	2.7.1.107	ko:K00901	ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
CMS1_k127_3930295_2	933262.AXAM01000014_gene258	2.052e-111	370.0	COG3528@1|root,COG3528@2|Bacteria,1R601@1224|Proteobacteria,42Q98@68525|delta/epsilon subdivisions,2WM5S@28221|Deltaproteobacteria,2MNQ0@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2219)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2219
CMS1_k127_3930295_12	107635.AZUO01000001_gene2016	5.466e-06	49.0	COG3549@1|root,COG3549@2|Bacteria,1MZ4I@1224|Proteobacteria,2UD9W@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Plasmid maintenance system killer	-	-	-	-	-	-	-	-	-	-	-	-	HigB-like_toxin
CMS1_k127_3932113_1	1173024.KI912148_gene3619	1.189e-52	190.0	COG2135@1|root,COG2135@2|Bacteria,1G1SA@1117|Cyanobacteria,1JHC7@1189|Stigonemataceae	1117|Cyanobacteria	S	SOS response associated peptidase (SRAP)	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
CMS1_k127_3932113_0	633131.TR2A62_0536	6.553e-62	224.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2TR2B@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Sel1 domain protein repeat-containing protein	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
CMS1_k127_3932113_2	1254432.SCE1572_33050	1.176e-22	98.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,42MEM@68525|delta/epsilon subdivisions,2WKYA@28221|Deltaproteobacteria,2YU1C@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	kefB	-	-	ko:K03455,ko:K11745,ko:K11747	-	-	-	-	ko00000,ko02000	2.A.37,2.A.37.1.1,2.A.37.1.2	-	-	Na_H_Exchanger,TrkA_N
CMS1_k127_3971372_4	1123261.AXDW01000010_gene251	2.573e-27	112.0	COG0096@1|root,COG0096@2|Bacteria,1RDG3@1224|Proteobacteria,1S452@1236|Gammaproteobacteria,1X6IW@135614|Xanthomonadales	135614|Xanthomonadales	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
CMS1_k127_3971372_1	317025.Tcr_0310	1.754e-68	236.0	COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,1S1Z1@1236|Gammaproteobacteria,460IG@72273|Thiotrichales	72273|Thiotrichales	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
CMS1_k127_3971372_3	395493.BegalDRAFT_2608	1.202e-42	158.0	COG0256@1|root,COG0256@2|Bacteria,1RGY7@1224|Proteobacteria,1S5V2@1236|Gammaproteobacteria,460WC@72273|Thiotrichales	72273|Thiotrichales	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
CMS1_k127_3971372_0	519989.ECTPHS_13143	8.129e-69	237.0	COG0098@1|root,COG0098@2|Bacteria,1MUS4@1224|Proteobacteria,1RNEV@1236|Gammaproteobacteria,1WX2D@135613|Chromatiales	135613|Chromatiales	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
CMS1_k127_3971372_5	314285.KT71_01010	7.291e-17	82.0	COG1841@1|root,COG1841@2|Bacteria,1N6ZE@1224|Proteobacteria,1SC8N@1236|Gammaproteobacteria,1JB5J@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Ribosomal protein L30p/L7e	rpmD	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
CMS1_k127_3971372_2	998674.ATTE01000001_gene4300	3.107e-55	197.0	COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,1S3P6@1236|Gammaproteobacteria,460T4@72273|Thiotrichales	72273|Thiotrichales	J	binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
CMS1_k127_4020780_20	105559.Nwat_1105	3.843e-51	188.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,1RPMP@1236|Gammaproteobacteria,1WYSG@135613|Chromatiales	135613|Chromatiales	M	FKBP-type peptidyl-prolyl isomerase	-	-	5.2.1.8	ko:K03773	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
CMS1_k127_4020780_22	118163.Ple7327_1388	1.21e-46	177.0	COG0500@1|root,COG0500@2|Bacteria,1GIUU@1117|Cyanobacteria,3VM0T@52604|Pleurocapsales	1117|Cyanobacteria	Q	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
CMS1_k127_4020780_17	696747.NIES39_B00380	6.534e-66	235.0	COG0457@1|root,COG0457@2|Bacteria,1G41Y@1117|Cyanobacteria	1117|Cyanobacteria	S	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
CMS1_k127_4020780_18	243233.MCA1751	3.386e-55	203.0	COG1073@1|root,COG1073@2|Bacteria,1QXQ2@1224|Proteobacteria	1224|Proteobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4020780_6	105559.Nwat_3016	1.93e-127	417.0	COG0042@1|root,COG0042@2|Bacteria,1MUY1@1224|Proteobacteria,1RN28@1236|Gammaproteobacteria,1WW7E@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs	dusA	-	-	ko:K05539	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
CMS1_k127_4020780_15	223926.28805501	8.074e-70	243.0	COG3066@1|root,COG3066@2|Bacteria,1MVYX@1224|Proteobacteria,1RQVV@1236|Gammaproteobacteria,1XV3G@135623|Vibrionales	135623|Vibrionales	L	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair	mutH	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360	-	ko:K03573	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutH
CMS1_k127_4020780_0	187272.Mlg_1865	4.448e-304	955.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,1RN5T@1236|Gammaproteobacteria,1WWDB@135613|Chromatiales	135613|Chromatiales	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,DUF294,GlnD_UR_UTase,HD,NTP_transf_2
CMS1_k127_4020780_5	768671.ThimaDRAFT_2160	4.133e-129	416.0	COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,1RMHN@1236|Gammaproteobacteria,1WX9V@135613|Chromatiales	135613|Chromatiales	E	TIGRFAM methionine aminopeptidase, type I	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
CMS1_k127_4020780_8	187272.Mlg_1863	4.483e-104	348.0	COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,1RN0Z@1236|Gammaproteobacteria,1WW47@135613|Chromatiales	135613|Chromatiales	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
CMS1_k127_4020780_12	519989.ECTPHS_08458	2.293e-94	318.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,1RPBJ@1236|Gammaproteobacteria,1WXRN@135613|Chromatiales	135613|Chromatiales	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
CMS1_k127_4020780_10	395493.BegalDRAFT_3261	2.573e-101	334.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,1RMHX@1236|Gammaproteobacteria,45ZYP@72273|Thiotrichales	72273|Thiotrichales	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
CMS1_k127_4020780_16	765914.ThisiDRAFT_1083	2.577e-67	235.0	COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,1RN75@1236|Gammaproteobacteria,1WY5S@135613|Chromatiales	135613|Chromatiales	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
CMS1_k127_4020780_13	395493.BegalDRAFT_3263	1.639e-84	289.0	COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,1RMVX@1236|Gammaproteobacteria,460AI@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
CMS1_k127_4020780_21	472759.Nhal_2457	3.405e-50	189.0	COG0575@1|root,COG0575@2|Bacteria,1MWSV@1224|Proteobacteria,1RQ6M@1236|Gammaproteobacteria,1X2WY@135613|Chromatiales	135613|Chromatiales	I	Belongs to the CDS family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
CMS1_k127_4020780_3	519989.ECTPHS_08483	2.202e-161	518.0	COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,1RNNW@1236|Gammaproteobacteria,1WX71@135613|Chromatiales	135613|Chromatiales	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
CMS1_k127_4020780_4	1283300.ATXB01000001_gene252	1.75e-129	428.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,1RMIX@1236|Gammaproteobacteria,1XDVY@135618|Methylococcales	135618|Methylococcales	M	zinc metalloprotease	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
CMS1_k127_4020780_1	395493.BegalDRAFT_3267	3.9e-256	810.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,1RMAP@1236|Gammaproteobacteria,4604N@72273|Thiotrichales	72273|Thiotrichales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
CMS1_k127_4020780_23	1198232.CYCME_1579	9.891e-44	166.0	COG2825@1|root,COG2825@2|Bacteria,1RD8X@1224|Proteobacteria,1RQIE@1236|Gammaproteobacteria,460W6@72273|Thiotrichales	72273|Thiotrichales	M	Belongs to the skp family	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
CMS1_k127_4020780_9	754477.Q7C_713	6.435e-102	341.0	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,1RNYI@1236|Gammaproteobacteria,46035@72273|Thiotrichales	72273|Thiotrichales	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
CMS1_k127_4020780_19	572477.Alvin_2055	2.647e-51	186.0	COG0764@1|root,COG0764@2|Bacteria,1RH2T@1224|Proteobacteria,1S63E@1236|Gammaproteobacteria,1WWV2@135613|Chromatiales	135613|Chromatiales	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
CMS1_k127_4020780_11	1304883.KI912532_gene2596	5.789e-99	329.0	COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,2VHDG@28216|Betaproteobacteria,2KV6X@206389|Rhodocyclales	206389|Rhodocyclales	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
CMS1_k127_4020780_7	1469245.JFBG01000023_gene1258	7.086e-107	358.0	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,1RNS1@1236|Gammaproteobacteria,1WY1X@135613|Chromatiales	135613|Chromatiales	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
CMS1_k127_4020780_14	1049564.TevJSym_ba00040	1.707e-72	249.0	COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,1RQ4B@1236|Gammaproteobacteria,1J5VG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
CMS1_k127_4020780_2	472759.Nhal_2673	8.645e-188	597.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,1RP0K@1236|Gammaproteobacteria,1WVZ3@135613|Chromatiales	135613|Chromatiales	L	DNA polymerase III alpha subunit	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,Intein_splicing,LAGLIDADG_3,PHP,tRNA_anti-codon
CMS1_k127_4065644_8	472759.Nhal_0465	3.313e-78	268.0	COG0647@1|root,COG0647@2|Bacteria,1QGX4@1224|Proteobacteria,1RRS1@1236|Gammaproteobacteria,1WW2T@135613|Chromatiales	135613|Chromatiales	G	TIGRFAM HAD-superfamily subfamily IIA hydrolase like protein	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_6,Hydrolase_like
CMS1_k127_4065644_10	713586.KB900536_gene1532	9.965e-38	145.0	COG1694@1|root,COG1694@2|Bacteria,1N02D@1224|Proteobacteria,1S8RW@1236|Gammaproteobacteria,1X2HD@135613|Chromatiales	135613|Chromatiales	S	MazG-like family	-	-	-	-	-	-	-	-	-	-	-	-	MazG-like
CMS1_k127_4065644_5	1333998.M2A_0859	1.525e-108	362.0	COG1294@1|root,COG1294@2|Bacteria,1MURP@1224|Proteobacteria,2TU3I@28211|Alphaproteobacteria,4BR9P@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	Cytochrome bd terminal oxidase subunit II	cydB	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
CMS1_k127_4065644_1	1033802.SSPSH_001936	3.202e-169	544.0	COG1271@1|root,COG1271@2|Bacteria,1MV60@1224|Proteobacteria,1RN2U@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	oxidase, subunit	cioA	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
CMS1_k127_4065644_2	323261.Noc_2216	7.71e-153	492.0	COG0577@1|root,COG0577@2|Bacteria,1MX7X@1224|Proteobacteria,1RRH7@1236|Gammaproteobacteria,1WX4G@135613|Chromatiales	135613|Chromatiales	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS1_k127_4065644_3	472759.Nhal_1201	1.134e-145	471.0	COG0577@1|root,COG0577@2|Bacteria,1MWBK@1224|Proteobacteria,1RPZF@1236|Gammaproteobacteria,1WXCH@135613|Chromatiales	135613|Chromatiales	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
CMS1_k127_4065644_6	1283300.ATXB01000001_gene37	1.1e-102	339.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RSA2@1236|Gammaproteobacteria,1XEQX@135618|Methylococcales	135618|Methylococcales	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_4065644_4	323261.Noc_2213	1.451e-117	392.0	COG0845@1|root,COG0845@2|Bacteria,1MUMV@1224|Proteobacteria,1S0KD@1236|Gammaproteobacteria,1WWDW@135613|Chromatiales	135613|Chromatiales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
CMS1_k127_4065644_12	1177181.T9A_01585	6.653e-10	69.0	COG5607@1|root,COG5607@2|Bacteria	2|Bacteria	F	PFAM CHAD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAD
CMS1_k127_4065644_9	1122604.JONR01000024_gene4640	7.216e-41	157.0	arCOG05203@1|root,31A0K@2|Bacteria,1RHZR@1224|Proteobacteria,1SS0Q@1236|Gammaproteobacteria,1X8RK@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4065644_0	1380394.JADL01000002_gene1654	4.255e-195	619.0	COG2855@1|root,COG2855@2|Bacteria,1PRHH@1224|Proteobacteria,2V9I6@28211|Alphaproteobacteria,2JY7M@204441|Rhodospirillales	204441|Rhodospirillales	S	Conserved hypothetical protein 698	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth698
CMS1_k127_4065644_7	879212.DespoDRAFT_02934	5.392e-98	332.0	COG3174@1|root,COG3174@2|Bacteria,1NDBI@1224|Proteobacteria,42QBM@68525|delta/epsilon subdivisions,2WNZE@28221|Deltaproteobacteria,2MNJM@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4010)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010,MgtC
CMS1_k127_4098932_3	472759.Nhal_3621	1.017e-86	298.0	COG0451@1|root,COG0451@2|Bacteria,1MX2J@1224|Proteobacteria,1RPHW@1236|Gammaproteobacteria,1WX5U@135613|Chromatiales	135613|Chromatiales	M	epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
CMS1_k127_4098932_2	395493.BegalDRAFT_3481	1.562e-94	320.0	COG0472@1|root,COG0472@2|Bacteria,1MWYW@1224|Proteobacteria,1RNAP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP- C55)	wbpL	-	-	ko:K13007	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
CMS1_k127_4098932_1	105559.Nwat_2113	4.7e-197	633.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,1RNQ2@1236|Gammaproteobacteria,1WW39@135613|Chromatiales	135613|Chromatiales	GM	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
CMS1_k127_4098932_0	1123368.AUIS01000027_gene1335	2.351e-219	687.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,1RMVW@1236|Gammaproteobacteria,2NCMC@225057|Acidithiobacillales	225057|Acidithiobacillales	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
CMS1_k127_4147196_1	1123399.AQVE01000015_gene1837	2.232e-254	794.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,1RNMI@1236|Gammaproteobacteria,45ZZ8@72273|Thiotrichales	72273|Thiotrichales	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
CMS1_k127_4147196_19	1049564.TevJSym_aa01860	2.213e-92	308.0	COG1051@1|root,COG1051@2|Bacteria,1QTT4@1224|Proteobacteria,1RQ35@1236|Gammaproteobacteria,1J69Z@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	COG1051 ADP-ribose pyrophosphatase	nuhA	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS1_k127_4147196_6	1502852.FG94_02756	3.379e-148	479.0	COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,2VH6N@28216|Betaproteobacteria,47296@75682|Oxalobacteraceae	28216|Betaproteobacteria	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
CMS1_k127_4147196_33	765914.ThisiDRAFT_1351	2.471e-53	194.0	COG1075@1|root,COG1075@2|Bacteria,1N2W0@1224|Proteobacteria,1SAMR@1236|Gammaproteobacteria,1WZS4@135613|Chromatiales	135613|Chromatiales	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
CMS1_k127_4147196_18	713586.KB900536_gene1054	1.6e-99	330.0	COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,1RP5N@1236|Gammaproteobacteria,1WX1Y@135613|Chromatiales	135613|Chromatiales	K	transcriptional regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
CMS1_k127_4147196_35	1279017.AQYJ01000022_gene2664	2.835e-49	181.0	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,1RQPJ@1236|Gammaproteobacteria,466I2@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
CMS1_k127_4147196_10	518766.Rmar_1990	1.252e-122	403.0	COG4257@1|root,COG4257@2|Bacteria	2|Bacteria	V	antibiotic catabolic process	-	-	-	ko:K18235	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	DUF5011
CMS1_k127_4147196_29	396588.Tgr7_2235	1.031e-69	242.0	COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,1RMET@1236|Gammaproteobacteria,1WX5V@135613|Chromatiales	135613|Chromatiales	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
CMS1_k127_4147196_4	187272.Mlg_2777	2.918e-163	520.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,1RNWY@1236|Gammaproteobacteria,1WWB3@135613|Chromatiales	135613|Chromatiales	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
CMS1_k127_4147196_39	1116472.MGMO_52c00330	1.889e-40	153.0	COG0824@1|root,COG0824@2|Bacteria,1MZH6@1224|Proteobacteria,1S93F@1236|Gammaproteobacteria,1XFE7@135618|Methylococcales	135618|Methylococcales	S	Tol-Pal system-associated acyl-CoA thioesterase	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
CMS1_k127_4147196_25	572477.Alvin_0952	3.3e-81	276.0	COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,1RMD4@1236|Gammaproteobacteria,1WWA0@135613|Chromatiales	135613|Chromatiales	U	PFAM MotA TolQ ExbB proton channel	-	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
CMS1_k127_4147196_37	1123236.KB899389_gene2203	9.636e-46	169.0	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,1S8RS@1236|Gammaproteobacteria,4679Y@72275|Alteromonadaceae	1236|Gammaproteobacteria	U	Biopolymer transport protein	tolR	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032153,GO:0042221,GO:0042493,GO:0042886,GO:0042891,GO:0043213,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	ExbD
CMS1_k127_4147196_49	686340.Metal_2818	9.995e-14	81.0	COG3064@1|root,COG3064@2|Bacteria,1RE5F@1224|Proteobacteria,1T53B@1236|Gammaproteobacteria,1XEYN@135618|Methylococcales	135618|Methylococcales	M	TonB C terminal	-	-	-	ko:K03646	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	TonB_2
CMS1_k127_4147196_7	396588.Tgr7_2229	1.817e-143	467.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,1RMCY@1236|Gammaproteobacteria,1WVZJ@135613|Chromatiales	135613|Chromatiales	U	Involved in the TonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
CMS1_k127_4147196_36	1286106.MPL1_01259	3.734e-46	173.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,1S8RG@1236|Gammaproteobacteria,460Y2@72273|Thiotrichales	72273|Thiotrichales	M	Belongs to the ompA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
CMS1_k127_4147196_38	1049564.TevJSym_be00190	6.301e-41	163.0	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,1RQWA@1236|Gammaproteobacteria,1J6G5@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	D	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	cpoB	GO:0005575,GO:0005623,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043933,GO:0044085,GO:0044464,GO:0051259,GO:0051260,GO:0051301,GO:0065003,GO:0071840	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TolA_bind_tri
CMS1_k127_4147196_21	1163617.SCD_n00679	2.371e-89	303.0	COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,2VGZ7@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008144,GO:0016829,GO:0016840,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:1901681,GO:1904047	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
CMS1_k127_4147196_17	1001585.MDS_1315	1.127e-99	329.0	COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,1RMG9@1236|Gammaproteobacteria,1YCVM@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
CMS1_k127_4147196_30	1122194.AUHU01000005_gene971	2.117e-66	244.0	COG0834@1|root,COG4623@1|root,COG0834@2|Bacteria,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,1RM8W@1236|Gammaproteobacteria,467JF@72275|Alteromonadaceae	1236|Gammaproteobacteria	EMT	Bacterial periplasmic substrate-binding proteins	-	GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944	-	ko:K18691	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	SBP_bac_3,SLT
CMS1_k127_4147196_27	572477.Alvin_2540	2.752e-77	265.0	COG1208@1|root,COG1208@2|Bacteria,1R9ZD@1224|Proteobacteria,1S23A@1236|Gammaproteobacteria,1WWYC@135613|Chromatiales	135613|Chromatiales	JM	PFAM Nucleotidyl transferase	-	-	2.7.7.99	ko:K00992	ko00520,ko01100,map00520,map01100	-	R11025	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
CMS1_k127_4147196_14	1049564.TevJSym_ao00360	7.09e-108	359.0	COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,1RQ1Q@1236|Gammaproteobacteria,1J50Q@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	related to Ser Thr protein kinases	-	GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006022,GO:0006040,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564	2.7.1.221	ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH
CMS1_k127_4147196_9	519989.ECTPHS_01704	2.314e-130	424.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,1RMT9@1236|Gammaproteobacteria,1WWFJ@135613|Chromatiales	135613|Chromatiales	M	Arabinose 5-phosphate isomerase	-	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
CMS1_k127_4147196_31	1249627.D779_0313	5.772e-64	224.0	COG1778@1|root,COG1778@2|Bacteria,1RH85@1224|Proteobacteria,1S6D0@1236|Gammaproteobacteria,1WY5Q@135613|Chromatiales	135613|Chromatiales	S	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate	-	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_3
CMS1_k127_4147196_48	1502770.JQMG01000001_gene624	1.175e-15	85.0	COG3117@1|root,COG3117@2|Bacteria,1R5UK@1224|Proteobacteria,2VU37@28216|Betaproteobacteria,2KMR4@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Lipopolysaccharide-assembly, LptC-related	-	-	-	ko:K11719	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptC
CMS1_k127_4147196_44	472759.Nhal_0336	1.944e-28	121.0	COG1934@1|root,COG3103@1|root,COG1934@2|Bacteria,COG3103@2|Bacteria,1N776@1224|Proteobacteria,1RPM7@1236|Gammaproteobacteria,1WYD5@135613|Chromatiales	135613|Chromatiales	T	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm	lptA	-	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA,SH3_3
CMS1_k127_4147196_16	672.VV93_v1c04170	2.835e-100	333.0	COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,1RPW1@1236|Gammaproteobacteria,1XT67@135623|Vibrionales	135623|Vibrionales	S	abc transporter atp-binding protein	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
CMS1_k127_4147196_3	69328.PVLB_20360	3.474e-170	548.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,1RMY0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoN	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0042802,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
CMS1_k127_4147196_41	472759.Nhal_0333	3.714e-38	148.0	COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,1S8U1@1236|Gammaproteobacteria,1WYWY@135613|Chromatiales	135613|Chromatiales	J	Sigma 54 modulation protein	-	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
CMS1_k127_4147196_20	396588.Tgr7_0723	3.364e-92	314.0	COG1493@1|root,COG1493@2|Bacteria,1NNN5@1224|Proteobacteria,1S02U@1236|Gammaproteobacteria,1WX9F@135613|Chromatiales	135613|Chromatiales	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
CMS1_k127_4147196_22	395493.BegalDRAFT_1186	5.46e-89	303.0	COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,1RNJX@1236|Gammaproteobacteria,460MS@72273|Thiotrichales	72273|Thiotrichales	S	Displays ATPase and GTPase activities	-	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
CMS1_k127_4147196_43	555778.Hneap_0745	5.189e-29	122.0	COG2893@1|root,COG2893@2|Bacteria,1RHH7@1224|Proteobacteria,1SA62@1236|Gammaproteobacteria,1WYYD@135613|Chromatiales	135613|Chromatiales	G	system, fructose subfamily IIA component	-	-	2.7.1.194	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	M00283,M00550	R07671	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.7.1	-	-	EIIA-man
CMS1_k127_4147196_46	765914.ThisiDRAFT_0193	4.581e-27	112.0	COG1925@1|root,COG1925@2|Bacteria,1N6RM@1224|Proteobacteria,1SCXX@1236|Gammaproteobacteria,1WYUA@135613|Chromatiales	135613|Chromatiales	G	Phosphotransferase System	-	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
CMS1_k127_4147196_2	472759.Nhal_0327	3.976e-200	641.0	COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,1RN6R@1236|Gammaproteobacteria,1WWBU@135613|Chromatiales	135613|Chromatiales	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	-	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
CMS1_k127_4147196_8	1260251.SPISAL_07030	6.574e-134	440.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,1RNE4@1236|Gammaproteobacteria,1WW0B@135613|Chromatiales	135613|Chromatiales	P	Acts as a magnesium transporter	-	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
CMS1_k127_4147196_45	1049564.TevJSym_as00410	7.615e-28	117.0	2C1YJ@1|root,32ZXK@2|Bacteria,1N98H@1224|Proteobacteria,1SD8N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2782)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2782
CMS1_k127_4147196_15	187272.Mlg_2861	1.118e-104	344.0	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,1RSPA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
CMS1_k127_4147196_0	243233.MCA2573	0.0	1143.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,1XEFJ@135618|Methylococcales	135618|Methylococcales	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
CMS1_k127_4147196_13	395493.BegalDRAFT_1154	4.818e-113	369.0	COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,1RN3M@1236|Gammaproteobacteria,45ZZE@72273|Thiotrichales	72273|Thiotrichales	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
CMS1_k127_4147196_12	1056820.KB900641_gene527	1.02e-116	380.0	COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,1RPJQ@1236|Gammaproteobacteria,2PMY6@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	E	Histidine biosynthesis protein	hisF	GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009382,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234	-	ko:K01663,ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	iECO111_1330.ECO111_2749,iEcolC_1368.EcolC_1617,iYL1228.KPN_02481	His_biosynth
CMS1_k127_4147196_32	644801.Psest_3943	1.293e-53	191.0	COG0139@1|root,COG0139@2|Bacteria,1MW67@1224|Proteobacteria,1RMV4@1236|Gammaproteobacteria,1Z2SP@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	GO:0000105,GO:0003674,GO:0003824,GO:0004635,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iJN746.PP_5014	PRA-CH,PRA-PH
CMS1_k127_4147196_42	519989.ECTPHS_01534	1.973e-36	141.0	COG0140@1|root,COG0140@2|Bacteria,1MZEE@1224|Proteobacteria,1S8R4@1236|Gammaproteobacteria,1WYHH@135613|Chromatiales	135613|Chromatiales	E	phosphoribosyl-ATP pyrophosphohydrolase	hisE	-	3.6.1.31	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-PH
CMS1_k127_4147196_50	882378.RBRH_02282	3.384e-12	70.0	COG1826@1|root,COG1826@2|Bacteria,1N6S4@1224|Proteobacteria,2VVT6@28216|Betaproteobacteria,1K977@119060|Burkholderiaceae	28216|Betaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
CMS1_k127_4147196_51	1158165.KB898871_gene2399	3.941e-11	67.0	COG1826@1|root,COG1826@2|Bacteria,1N73F@1224|Proteobacteria,1SD9K@1236|Gammaproteobacteria,1WZ88@135613|Chromatiales	135613|Chromatiales	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation	tatB	-	-	ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
CMS1_k127_4147196_26	1249627.D779_0079	1.622e-78	271.0	COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,1RPRN@1236|Gammaproteobacteria,1WVX9@135613|Chromatiales	135613|Chromatiales	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
CMS1_k127_4147196_34	395493.BegalDRAFT_2140	3.998e-50	181.0	COG0607@1|root,COG0607@2|Bacteria,1REHH@1224|Proteobacteria,1S343@1236|Gammaproteobacteria,461CV@72273|Thiotrichales	72273|Thiotrichales	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CMS1_k127_4147196_5	105559.Nwat_0125	6.472e-156	496.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,1RP6Z@1236|Gammaproteobacteria,1WW7W@135613|Chromatiales	135613|Chromatiales	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
CMS1_k127_4147196_47	472759.Nhal_3855	1.016e-21	98.0	COG4391@1|root,COG4391@2|Bacteria,1N7QM@1224|Proteobacteria,1SHHF@1236|Gammaproteobacteria,1WZR6@135613|Chromatiales	135613|Chromatiales	S	Zinc-finger domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-CHCC
CMS1_k127_4147196_24	105559.Nwat_0592	3.355e-82	283.0	COG3660@1|root,COG3660@2|Bacteria,1RC47@1224|Proteobacteria,1S53F@1236|Gammaproteobacteria,1WZST@135613|Chromatiales	135613|Chromatiales	M	Mitochondrial fission ELM1	-	-	-	ko:K07276	-	-	-	-	ko00000	-	-	-	Mito_fiss_Elm1
CMS1_k127_4147196_40	402881.Plav_1325	5.775e-40	159.0	COG2227@1|root,COG2227@2|Bacteria,1NACD@1224|Proteobacteria,2VCHE@28211|Alphaproteobacteria,1JQH2@119043|Rhodobiaceae	28211|Alphaproteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
CMS1_k127_4147196_11	713586.KB900536_gene1647	8.204e-122	402.0	COG0438@1|root,COG0438@2|Bacteria,1MUTA@1224|Proteobacteria,1RS31@1236|Gammaproteobacteria,1WXR2@135613|Chromatiales	135613|Chromatiales	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS1_k127_4147196_28	323261.Noc_0576	2.771e-74	260.0	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria	1224|Proteobacteria	M	heptosyltransferase	-	-	-	ko:K02843,ko:K02849	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
CMS1_k127_4147196_23	713586.KB900536_gene1648	1.072e-84	291.0	COG0438@1|root,COG0438@2|Bacteria,1QF9A@1224|Proteobacteria,1RMDT@1236|Gammaproteobacteria,1WW1R@135613|Chromatiales	135613|Chromatiales	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS1_k127_4204225_4	522306.CAP2UW1_3069	8.565e-48	177.0	COG1595@1|root,COG1595@2|Bacteria,1N38X@1224|Proteobacteria,2VU1J@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
CMS1_k127_4204225_0	395493.BegalDRAFT_1319	2.858e-199	639.0	COG2304@1|root,COG2304@2|Bacteria,1MUTS@1224|Proteobacteria,1RQPC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	von willebrand factor, type A	yfbK	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	DUF3520,VWA,vWF_A
CMS1_k127_4204225_1	383372.Rcas_1810	1.371e-120	391.0	COG0863@1|root,COG2189@1|root,COG0863@2|Bacteria,COG2189@2|Bacteria,2GB10@200795|Chloroflexi,376FR@32061|Chloroflexia	32061|Chloroflexia	L	PFAM DNA methylase N-4 N-6 domain protein	-	-	2.1.1.72	ko:K07319	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
CMS1_k127_4204225_7	1040989.AWZU01000121_gene3966	2.068e-24	104.0	COG1942@1|root,COG1942@2|Bacteria,1Q0HZ@1224|Proteobacteria,2V2E0@28211|Alphaproteobacteria,3K223@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Tautomerase enzyme	-	-	5.3.2.6	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R03966,R05389	RC01040,RC01355	ko00000,ko00001,ko00002,ko01000	-	-	-	Tautomerase
CMS1_k127_4204225_2	857087.Metme_2457	1.565e-95	318.0	COG1733@1|root,COG1733@2|Bacteria,1PGWN@1224|Proteobacteria,1SXVP@1236|Gammaproteobacteria,1XGTB@135618|Methylococcales	135618|Methylococcales	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
CMS1_k127_4204225_6	396588.Tgr7_0187	3.27e-42	158.0	2DMVP@1|root,32TYU@2|Bacteria,1MZ9J@1224|Proteobacteria,1S9Z6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4204225_3	338963.Pcar_2495	2.965e-69	241.0	COG0430@1|root,COG0430@2|Bacteria,1MX7Q@1224|Proteobacteria,42MZG@68525|delta/epsilon subdivisions,2WKZ3@28221|Deltaproteobacteria,43UBA@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP	rtcA	-	6.5.1.4	ko:K01974	-	-	-	-	ko00000,ko01000	-	-	-	RTC,RTC_insert
CMS1_k127_4241197_10	1000565.METUNv1_01405	5.79e-69	236.0	COG2154@1|root,COG2154@2|Bacteria,1RIEN@1224|Proteobacteria,2VRX8@28216|Betaproteobacteria,2KYU2@206389|Rhodocyclales	206389|Rhodocyclales	H	Pterin 4 alpha carbinolamine dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Pterin_4a
CMS1_k127_4241197_14	697282.Mettu_2922	2.324e-46	177.0	COG0784@1|root,COG1891@1|root,COG0784@2|Bacteria,COG1891@2|Bacteria,1RGX0@1224|Proteobacteria,1S6UW@1236|Gammaproteobacteria,1XF0B@135618|Methylococcales	135618|Methylococcales	T	4-HFC-P synthase	-	-	-	-	-	-	-	-	-	-	-	-	4HFCP_synth
CMS1_k127_4241197_11	857087.Metme_2176	2.406e-66	232.0	COG2457@1|root,COG2457@2|Bacteria,1RD0V@1224|Proteobacteria,1S4RM@1236|Gammaproteobacteria,1XEYH@135618|Methylococcales	135618|Methylococcales	S	Protein of unknown function (DUF447)	-	-	-	ko:K09154	-	-	-	-	ko00000	-	-	-	DUF447
CMS1_k127_4241197_2	1236959.BAMT01000013_gene2997	3.399e-178	570.0	COG1404@1|root,COG1404@2|Bacteria,1QY39@1224|Proteobacteria,2WH9V@28216|Betaproteobacteria,2KPA6@206350|Nitrosomonadales	206350|Nitrosomonadales	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4241197_3	314607.KB13_310	8.881e-162	513.0	COG1235@1|root,COG1235@2|Bacteria,1MWI5@1224|Proteobacteria,2VJUF@28216|Betaproteobacteria	28216|Betaproteobacteria	S	May be involved in the transport of PQQ or its precursor to the periplasm	pqqB	-	-	ko:K06136	-	-	-	-	ko00000	-	-	-	Lactamase_B_2
CMS1_k127_4241197_5	998674.ATTE01000001_gene3352	8.487e-131	420.0	COG5424@1|root,COG5424@2|Bacteria,1MW7G@1224|Proteobacteria,1RP1V@1236|Gammaproteobacteria,461R8@72273|Thiotrichales	72273|Thiotrichales	H	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ	pqqC	-	1.3.3.11	ko:K06137	-	-	-	-	ko00000,ko01000	-	-	-	TENA_THI-4
CMS1_k127_4241197_15	472759.Nhal_3512	7.22e-29	117.0	2E4CK@1|root,32Z81@2|Bacteria,1N7JR@1224|Proteobacteria,1SCEZ@1236|Gammaproteobacteria,1WZFP@135613|Chromatiales	135613|Chromatiales	S	coenzyme PQQ synthesis	pqqD	-	-	ko:K06138	-	-	-	-	ko00000	-	-	-	PqqD
CMS1_k127_4241197_1	323261.Noc_2623	2.568e-184	582.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,1RMR1@1236|Gammaproteobacteria,1WWJ4@135613|Chromatiales	135613|Chromatiales	S	Radical SAM superfamily	pqqE	-	-	ko:K06139	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
CMS1_k127_4241197_6	243233.MCA2317	5.816e-106	350.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,1RM8G@1236|Gammaproteobacteria,1XE7A@135618|Methylococcales	135618|Methylococcales	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	-	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
CMS1_k127_4241197_7	1198232.CYCME_2189	2.162e-104	347.0	COG0596@1|root,COG0596@2|Bacteria,1MWW8@1224|Proteobacteria,1RMKF@1236|Gammaproteobacteria,45ZQB@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the peptidase S33 family	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
CMS1_k127_4241197_17	323261.Noc_0036	3.098e-16	90.0	2D1A4@1|root,32TA7@2|Bacteria,1N5RI@1224|Proteobacteria,1SFU2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SHOCT
CMS1_k127_4241197_8	1004785.AMBLS11_15275	3.076e-103	350.0	COG3203@1|root,COG3203@2|Bacteria,1N1M5@1224|Proteobacteria	1224|Proteobacteria	M	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	Porin_4
CMS1_k127_4241197_18	1469245.JFBG01000007_gene675	1.514e-07	57.0	2BIH4@1|root,32CPT@2|Bacteria,1NMG9@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4241197_16	1123399.AQVE01000032_gene780	1.826e-27	113.0	COG1977@1|root,COG1977@2|Bacteria,1QVHT@1224|Proteobacteria,1SJ9H@1236|Gammaproteobacteria,4634W@72273|Thiotrichales	72273|Thiotrichales	H	ThiS family	-	-	-	-	-	-	-	-	-	-	-	-	ThiS
CMS1_k127_4241197_4	395493.BegalDRAFT_3410	4.129e-161	517.0	COG0446@1|root,COG0446@2|Bacteria,1NR3M@1224|Proteobacteria,1RN6P@1236|Gammaproteobacteria,461X5@72273|Thiotrichales	72273|Thiotrichales	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
CMS1_k127_4241197_0	1123399.AQVE01000032_gene778	0.0	1045.0	COG2414@1|root,COG2414@2|Bacteria,1MWBB@1224|Proteobacteria,1RSCT@1236|Gammaproteobacteria,4624S@72273|Thiotrichales	72273|Thiotrichales	C	Aldehyde ferredoxin oxidoreductase, N-terminal domain	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
CMS1_k127_4241197_9	1469245.JFBG01000007_gene672	7.281e-76	257.0	COG1142@1|root,COG1142@2|Bacteria,1MUHW@1224|Proteobacteria,1RQWU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Formate hydrogenlyase	hyfA	-	-	ko:K12136,ko:K15827	-	-	-	-	ko00000,ko01000	-	-	iAF1260.b2724,iBWG_1329.BWG_2460,iE2348C_1286.E2348C_2989,iEC042_1314.EC042_2918,iECABU_c1320.ECABU_c29950,iECDH10B_1368.ECDH10B_2892,iECDH1ME8569_1439.ECDH1ME8569_2634,iECED1_1282.ECED1_3175,iECO111_1330.ECO111_3444,iECO26_1355.ECO26_3789,iECP_1309.ECP_2687,iECUMN_1333.ECUMN_3046,iETEC_1333.ETEC_2915,iEcDH1_1363.EcDH1_0965,iEcHS_1320.EcHS_A2860,iEcSMS35_1347.EcSMS35_2849,iEcolC_1368.EcolC_0988,iEcolC_1368.EcolC_1195,iJO1366.b2724,iJR904.b2724,iSFV_1184.SFV_2779,iSSON_1240.SSON_2871,iUMNK88_1353.UMNK88_3076,iUMNK88_1353.UMNK88_3397,iY75_1357.Y75_RS14175,ic_1306.c3284	Fer4,Fer4_3,Fer4_4,Fer4_6,Fer4_7,Fer4_9
CMS1_k127_4241197_12	1026882.MAMP_01709	3.555e-64	229.0	COG0683@1|root,COG0683@2|Bacteria,1MWGW@1224|Proteobacteria,1RQ5G@1236|Gammaproteobacteria,4638Q@72273|Thiotrichales	72273|Thiotrichales	E	TIGRFAM ABC transporter, substrate binding protein, PQQ-dependent alcohol dehydrogenase system	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
CMS1_k127_4241197_13	1026882.MAMP_01710	2.561e-52	188.0	COG3391@1|root,COG3391@2|Bacteria,1P862@1224|Proteobacteria,1RQZK@1236|Gammaproteobacteria,460F7@72273|Thiotrichales	72273|Thiotrichales	S	PQQ-dependent catabolism-associated beta-propeller protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1,Lactonase
CMS1_k127_4259251_1	1217718.ALOU01000031_gene1578	4.811e-125	452.0	COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,2VJEX@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	Neisseria PilC beta-propeller domain	pilY1	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Neisseria_PilC
CMS1_k127_4259251_20	1366050.N234_02020	1.584e-06	57.0	COG4726@1|root,COG4726@2|Bacteria,1N7I4@1224|Proteobacteria,2VVZB@28216|Betaproteobacteria,1KDEQ@119060|Burkholderiaceae	28216|Betaproteobacteria	NU	PilX N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PilX_N
CMS1_k127_4259251_10	1217718.ALOU01000031_gene1576	1.79e-50	195.0	COG4966@1|root,COG4966@2|Bacteria,1RC4Q@1224|Proteobacteria,2VS7N@28216|Betaproteobacteria,1K54M@119060|Burkholderiaceae	28216|Betaproteobacteria	NU	type 4 fimbrial biogenesis	pilW	-	-	ko:K02672	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	N_methyl,PilW
CMS1_k127_4259251_13	1283284.AZUK01000001_gene784	3.777e-26	115.0	COG4967@1|root,COG4967@2|Bacteria,1RK2M@1224|Proteobacteria,1SEYX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	type IV pilus modification protein PilV	-	-	-	ko:K02671	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	N_methyl
CMS1_k127_4259251_15	580332.Slit_2166	1.337e-15	85.0	COG4970@1|root,COG4970@2|Bacteria	2|Bacteria	NU	protein transport across the cell outer membrane	fimT	-	-	ko:K08084	-	-	-	-	ko00000,ko02044	3.A.15.2	-	-	GspH,N_methyl
CMS1_k127_4259251_14	296591.Bpro_2882	2.559e-22	101.0	COG4968@1|root,COG4968@2|Bacteria,1N6QE@1224|Proteobacteria,2VUU4@28216|Betaproteobacteria,4AFPB@80864|Comamonadaceae	28216|Betaproteobacteria	NU	Type IV minor pilin ComP, DNA uptake sequence receptor	-	-	-	ko:K02655	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	ComP_DUS,N_methyl
CMS1_k127_4259251_4	765912.Thimo_2492	7.142e-92	314.0	COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,1RQ50@1236|Gammaproteobacteria,1WWA9@135613|Chromatiales	135613|Chromatiales	C	PFAM FAD dependent oxidoreductase	-	-	1.4.3.19	ko:K03153	ko00730,ko01100,map00730,map01100	-	R07463	RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
CMS1_k127_4259251_11	1123393.KB891329_gene970	1.13e-42	161.0	COG0735@1|root,COG0735@2|Bacteria,1RH58@1224|Proteobacteria,2VT6I@28216|Betaproteobacteria,1KSD1@119069|Hydrogenophilales	119069|Hydrogenophilales	K	Ferric uptake regulator family	-	-	-	ko:K09826	-	-	-	-	ko00000,ko03000	-	-	-	FUR
CMS1_k127_4259251_18	2903.EOD35995	1.703e-08	65.0	COG0664@1|root,KOG1113@2759|Eukaryota	2759|Eukaryota	T	cAMP-dependent protein kinase regulator activity	-	-	-	ko:K04739,ko:K10409	ko04910,ko05016,map04910,map05016	-	-	-	ko00000,ko00001,ko04812	-	-	-	PAS,PP2C,Pkinase,cNMP_binding
CMS1_k127_4259251_16	604331.AUHY01000035_gene2448	1.632e-11	75.0	COG0664@1|root,COG0664@2|Bacteria,1WJXH@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	COGs COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase	-	GO:0000166,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0017076,GO:0019219,GO:0019222,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0046983,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CMS1_k127_4259251_21	65093.PCC7418_3399	0.0002314	52.0	COG0664@1|root,COG3264@1|root,COG0664@2|Bacteria,COG3264@2|Bacteria,1G2P9@1117|Cyanobacteria	1117|Cyanobacteria	MT	mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel,cNMP_binding
CMS1_k127_4259251_17	1499686.BN1079_02888	3.218e-09	68.0	COG3266@1|root,COG3267@1|root,COG3266@2|Bacteria,COG3267@2|Bacteria,1R5UY@1224|Proteobacteria	1224|Proteobacteria	U	Sporulation related domain	-	-	-	ko:K03112	-	-	-	-	ko00000	-	-	-	AAA_22,SPOR
CMS1_k127_4259251_9	633131.TR2A62_1584	2.759e-51	196.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2TR2B@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Sel1 domain protein repeat-containing protein	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
CMS1_k127_4259251_2	243233.MCA0508	3.152e-117	385.0	COG0373@1|root,COG0373@2|Bacteria,1R5VH@1224|Proteobacteria,1S2KV@1236|Gammaproteobacteria,1XEEN@135618|Methylococcales	135618|Methylococcales	C	PFAM Methylene-tetrahydromethanopterin dehydrogenase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Mpt_N
CMS1_k127_4259251_5	697282.Mettu_3646	4.151e-72	248.0	COG3404@1|root,COG3404@2|Bacteria,1R781@1224|Proteobacteria,1SFG9@1236|Gammaproteobacteria,1XEUC@135618|Methylococcales	135618|Methylococcales	E	Formiminotransferase-cyclodeaminase	fchA	-	-	-	-	-	-	-	-	-	-	-	FTCD_C
CMS1_k127_4259251_3	395493.BegalDRAFT_1954	1.28e-97	329.0	COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,1RMBU@1236|Gammaproteobacteria,45ZNU@72273|Thiotrichales	72273|Thiotrichales	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
CMS1_k127_4259251_6	1049564.TevJSym_ai00570	9.858e-71	243.0	COG3023@1|root,COG3023@2|Bacteria,1RDHU@1224|Proteobacteria,1S3PG@1236|Gammaproteobacteria,1J61Z@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	V	COG3023 Negative regulator of beta-lactamase expression	ampD	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043170,GO:0044424,GO:0044464,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	3.5.1.28	ko:K01447,ko:K03806	-	-	R04112	RC00064,RC00141	ko00000,ko01000,ko01011	-	-	iAF1260.b0110,iB21_1397.B21_00108,iBWG_1329.BWG_0103,iEC55989_1330.EC55989_0103,iECBD_1354.ECBD_3509,iECB_1328.ECB_00109,iECDH10B_1368.ECDH10B_0090,iECDH1ME8569_1439.ECDH1ME8569_0104,iECD_1391.ECD_00109,iECIAI1_1343.ECIAI1_0107,iECO103_1326.ECO103_0110,iECO111_1330.ECO111_0111,iECO26_1355.ECO26_0112,iECSE_1348.ECSE_0110,iECW_1372.ECW_m0107,iEKO11_1354.EKO11_3806,iETEC_1333.ETEC_0106,iEcDH1_1363.EcDH1_3492,iEcE24377_1341.EcE24377A_0112,iEcHS_1320.EcHS_A0114,iEcolC_1368.EcolC_3549,iJO1366.b0110,iSFV_1184.SFV_0101,iSF_1195.SF0107,iSFxv_1172.SFxv_0113,iS_1188.S0109,iUMNK88_1353.UMNK88_108,iWFL_1372.ECW_m0107,iY75_1357.Y75_RS00560	Amidase_2
CMS1_k127_4259251_12	1049564.TevJSym_aa00750	5.501e-31	133.0	COG1270@1|root,COG1270@2|Bacteria	2|Bacteria	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	cobD	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
CMS1_k127_4259251_7	1115512.EH105704_29_00100	1.095e-65	232.0	COG2908@1|root,COG2908@2|Bacteria,1N3U7@1224|Proteobacteria,1RP1X@1236|Gammaproteobacteria,3XNT3@561|Escherichia	1236|Gammaproteobacteria	S	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxH	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iE2348C_1286.E2348C_0457	Metallophos,Metallophos_2
CMS1_k127_4259251_8	1562701.BBOF01000022_gene709	2.221e-61	215.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,2VQ3Z@28216|Betaproteobacteria,1K11Z@119060|Burkholderiaceae	28216|Betaproteobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
CMS1_k127_4259251_0	765910.MARPU_07220	8.013e-203	642.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,1RP5K@1236|Gammaproteobacteria,1WW6E@135613|Chromatiales	135613|Chromatiales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
CMS1_k127_4259251_19	391615.ABSJ01000002_gene467	2.424e-07	55.0	2DU2E@1|root,33NN7@2|Bacteria,1P5P1@1224|Proteobacteria,1SV3F@1236|Gammaproteobacteria,1JBM0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4320250_5	713586.KB900536_gene1145	1.355e-112	367.0	COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,1RMU3@1236|Gammaproteobacteria,1WWB2@135613|Chromatiales	135613|Chromatiales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
CMS1_k127_4320250_11	1049564.TevJSym_aa00280	3.298e-50	184.0	COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,1S3QK@1236|Gammaproteobacteria,1J60B@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	J	Ribosomal protein L17	rplQ	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
CMS1_k127_4320250_8	443598.AUFA01000003_gene2144	2.163e-75	261.0	COG1912@1|root,COG1912@2|Bacteria,1MV99@1224|Proteobacteria,2TVNY@28211|Alphaproteobacteria,3K2NE@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
CMS1_k127_4320250_1	519989.ECTPHS_09268	5.911e-225	708.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,1RP7U@1236|Gammaproteobacteria,1WX4J@135613|Chromatiales	135613|Chromatiales	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
CMS1_k127_4320250_0	754476.Q7A_2838	1.419e-228	715.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RP7E@1236|Gammaproteobacteria,45ZRF@72273|Thiotrichales	72273|Thiotrichales	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
CMS1_k127_4320250_12	1249627.D779_0068	3.346e-30	121.0	COG0721@1|root,COG0721@2|Bacteria,1MZQP@1224|Proteobacteria,1S8VY@1236|Gammaproteobacteria,1WZ25@135613|Chromatiales	135613|Chromatiales	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
CMS1_k127_4320250_3	1049564.TevJSym_ao00750	1.223e-182	575.0	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,1RN82@1236|Gammaproteobacteria,1J52U@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	D	COG1077 Actin-like ATPase involved in cell morphogenesis	mreB	GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005856,GO:0005886,GO:0007049,GO:0008150,GO:0008360,GO:0009987,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0032505,GO:0042802,GO:0043093,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051301,GO:0051302,GO:0051782,GO:0051983,GO:0065007,GO:0065008,GO:0071944	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
CMS1_k127_4320250_7	472759.Nhal_0569	1.256e-80	277.0	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,1RMK4@1236|Gammaproteobacteria,1WWKS@135613|Chromatiales	135613|Chromatiales	M	Involved in formation and maintenance of cell shape	-	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
CMS1_k127_4320250_9	396588.Tgr7_0512	5.812e-56	200.0	COG2891@1|root,COG2891@2|Bacteria,1RER7@1224|Proteobacteria,1S8VI@1236|Gammaproteobacteria,1WYH2@135613|Chromatiales	135613|Chromatiales	M	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins	-	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
CMS1_k127_4320250_2	395493.BegalDRAFT_0708	9.711e-205	654.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,1RN9H@1236|Gammaproteobacteria,45ZU0@72273|Thiotrichales	72273|Thiotrichales	M	Catalyzes cross-linking of the peptidoglycan cell wall	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
CMS1_k127_4320250_4	713586.KB900536_gene2642	4.934e-137	445.0	COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,1RMEJ@1236|Gammaproteobacteria,1WWAV@135613|Chromatiales	135613|Chromatiales	M	Peptidoglycan polymerase that is essential for cell wall elongation	mrdB	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
CMS1_k127_4320250_6	1316927.ATKI01000019_gene1708	3.449e-98	330.0	COG2951@1|root,COG2951@2|Bacteria,1MUZ3@1224|Proteobacteria,1RMQ6@1236|Gammaproteobacteria,1YPQY@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	M	Lytic murein transglycosylase B	mltB	-	-	ko:K08305	-	-	-	-	ko00000,ko01000,ko01011	-	GH103	-	SLT_2
CMS1_k127_4320250_10	754476.Q7A_2830	1.782e-53	192.0	COG0797@1|root,COG3087@1|root,COG0797@2|Bacteria,COG3087@2|Bacteria,1MZ8S@1224|Proteobacteria,1RMCG@1236|Gammaproteobacteria,4610F@72273|Thiotrichales	72273|Thiotrichales	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,SPOR
CMS1_k127_4344891_4	105559.Nwat_1369	1.357e-118	400.0	COG1033@1|root,COG1033@2|Bacteria,1QW3H@1224|Proteobacteria,1RZA3@1236|Gammaproteobacteria,1X2NT@135613|Chromatiales	135613|Chromatiales	S	TIGRFAM hopanoid biosynthesis associated RND transporter like protein HpnN	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
CMS1_k127_4344891_7	211165.AJLN01000120_gene792	1.057e-70	244.0	COG0558@1|root,COG0558@2|Bacteria	2|Bacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	-	-	-	-	-	-	-	-	-	-	CDP-OH_P_transf
CMS1_k127_4344891_3	1266925.JHVX01000012_gene1720	3.591e-136	440.0	COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,2VIQ7@28216|Betaproteobacteria,3726X@32003|Nitrosomonadales	28216|Betaproteobacteria	M	NmrA-like family	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
CMS1_k127_4344891_9	211165.AJLN01000120_gene792	1.559e-31	131.0	COG0558@1|root,COG0558@2|Bacteria	2|Bacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	-	-	-	-	-	-	-	-	-	-	CDP-OH_P_transf
CMS1_k127_4344891_8	395493.BegalDRAFT_0847	2.935e-42	162.0	COG1999@1|root,COG1999@2|Bacteria,1RHSV@1224|Proteobacteria,1S6HW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
CMS1_k127_4344891_10	1121028.ARQE01000002_gene1985	2.813e-25	112.0	COG2847@1|root,COG2847@2|Bacteria,1MZ3M@1224|Proteobacteria,2UBUR@28211|Alphaproteobacteria,2PK62@255475|Aurantimonadaceae	28211|Alphaproteobacteria	S	Pfam:DUF461	-	-	-	ko:K09796	-	-	-	-	ko00000,ko03110	-	-	-	PCuAC
CMS1_k127_4344891_6	1452718.JBOY01000007_gene3375	1.268e-88	301.0	COG0688@1|root,COG0688@2|Bacteria,1MVT4@1224|Proteobacteria,1RN1U@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
CMS1_k127_4344891_5	1173024.KI912148_gene4881	2.127e-105	357.0	COG0531@1|root,COG0531@2|Bacteria,1G2GM@1117|Cyanobacteria,1JHRW@1189|Stigonemataceae	1117|Cyanobacteria	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
CMS1_k127_4344891_11	82654.Pse7367_3630	1.287e-16	91.0	2DTGM@1|root,33K91@2|Bacteria	2|Bacteria	S	PFAM Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1
CMS1_k127_4344891_2	395493.BegalDRAFT_1892	1.354e-165	534.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,1RPJB@1236|Gammaproteobacteria,4605J@72273|Thiotrichales	72273|Thiotrichales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
CMS1_k127_4344891_0	396588.Tgr7_0998	1.833e-229	720.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,1RNI4@1236|Gammaproteobacteria,1WXM2@135613|Chromatiales	135613|Chromatiales	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
CMS1_k127_4344891_1	1026882.MAMP_00775	4.106e-186	591.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,1RNKN@1236|Gammaproteobacteria,45ZMF@72273|Thiotrichales	72273|Thiotrichales	CP	Proton-translocating NADH-quinone oxidoreductase, chain L	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
CMS1_k127_4380659_14	396588.Tgr7_0439	1.157e-19	89.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,1RMTB@1236|Gammaproteobacteria,1WWXH@135613|Chromatiales	135613|Chromatiales	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
CMS1_k127_4380659_8	765912.Thimo_0176	5.666e-43	158.0	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,1S8YR@1236|Gammaproteobacteria,1WYJ2@135613|Chromatiales	135613|Chromatiales	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
CMS1_k127_4380659_12	1279017.AQYJ01000025_gene752	6.143e-31	128.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,1T4K6@1236|Gammaproteobacteria,46DC0@72275|Alteromonadaceae	1236|Gammaproteobacteria	KLT	Sulfatase-modifying factor enzyme 1	ppkA	-	2.7.11.1	ko:K11912	ko02025,ko03070,map02025,map03070	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02044	-	-	-	FGE-sulfatase,PEGA,Pkinase
CMS1_k127_4380659_4	686340.Metal_3581	4.43e-88	325.0	COG0642@1|root,COG3829@1|root,COG2205@2|Bacteria,COG3829@2|Bacteria,1NRP8@1224|Proteobacteria,1RX1M@1236|Gammaproteobacteria,1XG7H@135618|Methylococcales	135618|Methylococcales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
CMS1_k127_4380659_19	1123248.KB893359_gene2120	0.0006139	49.0	COG2198@1|root,COG2198@2|Bacteria,4PJD7@976|Bacteroidetes,1J02M@117747|Sphingobacteriia	976|Bacteroidetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4380659_10	1121878.AUGL01000005_gene2712	7.611e-34	141.0	COG2199@1|root,COG3706@2|Bacteria,1RDXH@1224|Proteobacteria,1S3QY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
CMS1_k127_4380659_18	1227487.C474_03920	3.292e-07	63.0	COG0784@1|root,arCOG02333@2157|Archaea,2XST7@28890|Euryarchaeota,23S1Y@183963|Halobacteria	183963|Halobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
CMS1_k127_4380659_15	765914.ThisiDRAFT_1000	1.085e-18	101.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1PJCA@1224|Proteobacteria,1RS4H@1236|Gammaproteobacteria,1WWNV@135613|Chromatiales	135613|Chromatiales	T	PFAM EAL domain	-	-	-	ko:K21025	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	EAL,GGDEF,PAS,PAS_8,PAS_9,Response_reg
CMS1_k127_4380659_11	1267535.KB906767_gene4225	7.194e-33	131.0	COG1324@1|root,COG1324@2|Bacteria,3Y5P7@57723|Acidobacteria	57723|Acidobacteria	P	CutA1 divalent ion tolerance protein	-	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
CMS1_k127_4380659_1	243233.MCA1041	1.65e-164	537.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,1RPF7@1236|Gammaproteobacteria,1XDNX@135618|Methylococcales	135618|Methylococcales	CO	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
CMS1_k127_4380659_9	396588.Tgr7_0371	8.546e-40	156.0	COG0526@1|root,COG0526@2|Bacteria,1MZ5J@1224|Proteobacteria,1SASG@1236|Gammaproteobacteria,1WYFK@135613|Chromatiales	135613|Chromatiales	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
CMS1_k127_4380659_6	580332.Slit_2853	1.881e-54	194.0	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,2VR4Y@28216|Betaproteobacteria,44VUG@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
CMS1_k127_4380659_7	1441629.PCH70_46680	4.67e-44	164.0	COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,1S3YP@1236|Gammaproteobacteria,1Z51R@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	GO:0003674,GO:0003824,GO:0003989,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009305,GO:0009987,GO:0016049,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	iYL1228.KPN_03664	Biotin_lipoyl
CMS1_k127_4380659_0	572477.Alvin_1906	5.767e-228	712.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,1RMNB@1236|Gammaproteobacteria,1WWPY@135613|Chromatiales	135613|Chromatiales	I	TIGRFAM acetyl-CoA carboxylase, biotin carboxylase	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
CMS1_k127_4380659_3	105559.Nwat_2753	6.072e-89	308.0	COG2206@1|root,COG2206@2|Bacteria,1MW7F@1224|Proteobacteria,1RPEZ@1236|Gammaproteobacteria,1WX4U@135613|Chromatiales	135613|Chromatiales	T	PFAM Metal-dependent phosphohydrolase, HD	-	-	-	-	-	-	-	-	-	-	-	-	DUF3391,HD_5
CMS1_k127_4380659_5	318161.Sden_0446	6.563e-66	236.0	COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,1RNAR@1236|Gammaproteobacteria,2QA5F@267890|Shewanellaceae	1236|Gammaproteobacteria	J	Methylates ribosomal protein L11	prmA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006480,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018011,GO:0018012,GO:0018022,GO:0018023,GO:0018193,GO:0018194,GO:0018205,GO:0019538,GO:0031365,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
CMS1_k127_4380659_13	396588.Tgr7_0364	1.713e-25	116.0	COG1273@1|root,COG1273@2|Bacteria,1MWCU@1224|Proteobacteria,1S892@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3426)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3426,zinc_ribbon_5
CMS1_k127_4380659_2	1131553.JIBI01000001_gene1564	5.828e-127	415.0	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,2VHBP@28216|Betaproteobacteria,371XV@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dusB	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
CMS1_k127_4380659_16	1117647.M5M_15620	1.129e-17	87.0	COG2901@1|root,COG2901@2|Bacteria,1N7MJ@1224|Proteobacteria,1SD35@1236|Gammaproteobacteria,1J6UC@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters	fis	GO:0000018,GO:0000229,GO:0000785,GO:0000786,GO:0000787,GO:0000789,GO:0000976,GO:0000984,GO:0000985,GO:0001017,GO:0001046,GO:0001047,GO:0001067,GO:0001121,GO:0001130,GO:0001131,GO:0001140,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008301,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016032,GO:0016070,GO:0018130,GO:0019042,GO:0019045,GO:0019046,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031421,GO:0032359,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0042803,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044374,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044427,GO:0044444,GO:0044446,GO:0044464,GO:0044815,GO:0045892,GO:0045893,GO:0045911,GO:0045934,GO:0045935,GO:0046483,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051054,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	ko:K03557	ko05111,map05111	-	-	-	ko00000,ko00001,ko03000,ko03036,ko03400	-	-	-	HTH_8
CMS1_k127_4380659_17	697282.Mettu_2626	3.76e-11	64.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,1RMWS@1236|Gammaproteobacteria,1XDUC@135618|Methylococcales	135618|Methylococcales	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
CMS1_k127_4414304_1	1120956.JHZK01000002_gene965	2.768e-78	269.0	COG4976@1|root,COG4976@2|Bacteria,1RA4U@1224|Proteobacteria	1224|Proteobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
CMS1_k127_4414304_0	396588.Tgr7_1012	3.087e-230	721.0	COG2308@1|root,COG2308@2|Bacteria,1MUAD@1224|Proteobacteria,1RNAF@1236|Gammaproteobacteria,1WVZB@135613|Chromatiales	135613|Chromatiales	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
CMS1_k127_4414304_2	498211.CJA_0987	3.025e-65	228.0	COG2307@1|root,COG2307@2|Bacteria,1MVZK@1224|Proteobacteria,1RN2Y@1236|Gammaproteobacteria,1FGDP@10|Cellvibrio	1236|Gammaproteobacteria	S	A predicted alpha-helical domain with a conserved ER motif.	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E
CMS1_k127_4488059_15	319003.Bra1253DRAFT_00003	4.814e-45	168.0	2B1WH@1|root,30C4Q@2|Bacteria,1R3E9@1224|Proteobacteria,2U7UN@28211|Alphaproteobacteria,3K27G@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	MAPEG family	-	-	-	-	-	-	-	-	-	-	-	-	MAPEG
CMS1_k127_4488059_13	519989.ECTPHS_01504	7.2e-51	190.0	COG0664@1|root,COG0664@2|Bacteria,1MVGE@1224|Proteobacteria,1RPTB@1236|Gammaproteobacteria,1WWQ7@135613|Chromatiales	135613|Chromatiales	K	Transcriptional regulator	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CMS1_k127_4488059_8	1082933.MEA186_19595	1.196e-85	291.0	COG0500@1|root,COG2226@2|Bacteria,1NWX3@1224|Proteobacteria,2TURQ@28211|Alphaproteobacteria,43PQD@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
CMS1_k127_4488059_18	330214.NIDE1237	1.128e-25	115.0	COG4454@1|root,COG4454@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K14588	-	-	-	-	ko00000	-	-	-	Copper-bind,Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3,Cupredoxin_1,SoxE
CMS1_k127_4488059_4	1268635.Loa_02056	1.896e-112	376.0	COG0644@1|root,COG0644@2|Bacteria,1RAS8@1224|Proteobacteria,1SI1S@1236|Gammaproteobacteria,1JE0Z@118969|Legionellales	118969|Legionellales	C	Tryptophan halogenase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
CMS1_k127_4488059_11	1120956.JHZK01000041_gene3070	2.636e-60	216.0	COG4123@1|root,COG4123@2|Bacteria,1RH1G@1224|Proteobacteria,2UBHZ@28211|Alphaproteobacteria,1JQ6I@119043|Rhodobiaceae	28211|Alphaproteobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25
CMS1_k127_4488059_3	365044.Pnap_2676	2.341e-123	405.0	COG3424@1|root,COG3424@2|Bacteria,1MUDX@1224|Proteobacteria,2W1AM@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Chalcone and stilbene synthases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Chal_sti_synt_C,FAE1_CUT1_RppA
CMS1_k127_4488059_12	323848.Nmul_A2110	5.14e-57	202.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,2VSHQ@28216|Betaproteobacteria,373GQ@32003|Nitrosomonadales	28216|Betaproteobacteria	C	SelR domain	msrB	-	1.8.4.11,1.8.4.12	ko:K07305,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	SelR
CMS1_k127_4488059_1	105559.Nwat_2049	2.61e-177	588.0	COG3857@1|root,COG3857@2|Bacteria,1QUQD@1224|Proteobacteria,1T20Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
CMS1_k127_4488059_0	472759.Nhal_2969	0.0	1030.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,1RPC6@1236|Gammaproteobacteria,1WWH2@135613|Chromatiales	135613|Chromatiales	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA	recB	-	3.1.11.5,3.6.4.12	ko:K03582,ko:K16898	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
CMS1_k127_4488059_19	207954.MED92_13903	1.684e-18	96.0	2CWJC@1|root,32SZT@2|Bacteria,1N5QU@1224|Proteobacteria,1SBQD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4488059_10	1033802.SSPSH_000090	2.837e-61	222.0	COG0730@1|root,COG0730@2|Bacteria,1MVBS@1224|Proteobacteria,1S62V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
CMS1_k127_4488059_17	565045.NOR51B_2797	4.209e-36	141.0	COG2391@1|root,COG2391@2|Bacteria,1MZ3A@1224|Proteobacteria,1S95T@1236|Gammaproteobacteria,1J6H0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
CMS1_k127_4488059_16	1541065.JRFE01000061_gene5867	2.112e-40	157.0	COG2391@1|root,COG2391@2|Bacteria,1G7H1@1117|Cyanobacteria,3VMUB@52604|Pleurocapsales	1117|Cyanobacteria	S	PFAM YeeE YedE family (DUF395)	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
CMS1_k127_4488059_2	1088721.NSU_3752	1.707e-150	488.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1MURA@1224|Proteobacteria,2TR1F@28211|Alphaproteobacteria,2K3NJ@204457|Sphingomonadales	204457|Sphingomonadales	P	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
CMS1_k127_4488059_14	247490.KSU1_B0405	6.897e-46	173.0	COG1765@1|root,COG1765@2|Bacteria	2|Bacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
CMS1_k127_4488059_7	1432050.IE4771_CH01153	1.024e-85	295.0	COG4977@1|root,COG4977@2|Bacteria,1MUDK@1224|Proteobacteria,2U1C5@28211|Alphaproteobacteria,4BC24@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI,HTH_18
CMS1_k127_4488059_6	1068978.AMETH_5158	4.712e-94	314.0	COG0846@1|root,COG0846@2|Bacteria,2GJI3@201174|Actinobacteria,4DZA5@85010|Pseudonocardiales	201174|Actinobacteria	K	Sir2 family	cobB2	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
CMS1_k127_4488059_5	472759.Nhal_2208	6.638e-98	328.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,1RNXH@1236|Gammaproteobacteria,1WW4N@135613|Chromatiales	135613|Chromatiales	C	PFAM aldo keto reductase	tas	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
CMS1_k127_4488059_9	862908.BMS_1128	2.435e-68	238.0	COG1432@1|root,COG1432@2|Bacteria,1QC1U@1224|Proteobacteria,42TAH@68525|delta/epsilon subdivisions,2WPYX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN
CMS1_k127_4515471_2	1173026.Glo7428_2144	7.623e-56	199.0	COG2135@1|root,COG2135@2|Bacteria,1G1SA@1117|Cyanobacteria	1117|Cyanobacteria	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
CMS1_k127_4515471_1	1033802.SSPSH_001314	4.91e-62	224.0	COG0300@1|root,COG0300@2|Bacteria,1MWNZ@1224|Proteobacteria,1RS01@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
CMS1_k127_4515471_3	589865.DaAHT2_0097	5.434e-21	94.0	COG1872@1|root,COG1872@2|Bacteria	2|Bacteria	I	DUF167	CP_0257	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
CMS1_k127_4515471_0	1286106.MPL1_11008	3.657e-220	691.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,1RMYD@1236|Gammaproteobacteria,4600V@72273|Thiotrichales	72273|Thiotrichales	E	Vitamin B12 dependent methionine synthase, activation	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
CMS1_k127_4523009_10	1232452.BAIB02000001_gene18	1.395e-06	51.0	2BZDJ@1|root,2ZPU3@2|Bacteria,1W5XA@1239|Firmicutes,255BW@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4523009_2	1123261.AXDW01000010_gene235	2.019e-223	696.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,1RMYX@1236|Gammaproteobacteria,1X48A@135614|Xanthomonadales	135614|Xanthomonadales	J	GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
CMS1_k127_4523009_9	1122165.AUHS01000042_gene440	1.429e-09	59.0	COG0690@1|root,COG0690@2|Bacteria,1RDI9@1224|Proteobacteria,1S3PA@1236|Gammaproteobacteria,1JECV@118969|Legionellales	118969|Legionellales	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
CMS1_k127_4523009_8	1123517.JOMR01000001_gene1894	4.747e-25	108.0	COG0690@1|root,COG0690@2|Bacteria	2|Bacteria	U	P-P-bond-hydrolysis-driven protein transmembrane transporter activity	secE	GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
CMS1_k127_4523009_4	1288826.MSNKSG1_17703	4.589e-91	301.0	COG0250@1|root,COG0250@2|Bacteria,1MU14@1224|Proteobacteria,1RMW0@1236|Gammaproteobacteria,4644G@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	Participates in transcription elongation, termination and antitermination	nusG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
CMS1_k127_4523009_5	1158756.AQXQ01000002_gene2058	8.184e-72	245.0	COG0080@1|root,COG0080@2|Bacteria,1RA2M@1224|Proteobacteria,1S22R@1236|Gammaproteobacteria,1WXZD@135613|Chromatiales	135613|Chromatiales	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
CMS1_k127_4523009_3	1232683.ADIMK_3612	1.338e-94	316.0	COG0081@1|root,COG0081@2|Bacteria,1MUE6@1224|Proteobacteria,1RMDW@1236|Gammaproteobacteria,4649G@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
CMS1_k127_4523009_6	243233.MCA1064	1.285e-60	213.0	COG0244@1|root,COG0244@2|Bacteria,1RAN5@1224|Proteobacteria,1S286@1236|Gammaproteobacteria,1XEHY@135618|Methylococcales	135618|Methylococcales	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
CMS1_k127_4523009_7	1268635.Loa_00380	6.233e-49	177.0	COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,1S5V7@1236|Gammaproteobacteria,1JEGD@118969|Legionellales	118969|Legionellales	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
CMS1_k127_4523009_0	472759.Nhal_2378	0.0	2095.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,1RMK0@1236|Gammaproteobacteria,1WX4P@135613|Chromatiales	135613|Chromatiales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
CMS1_k127_4523009_1	395493.BegalDRAFT_2897	1.211e-274	848.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,1RPYH@1236|Gammaproteobacteria,45ZP4@72273|Thiotrichales	72273|Thiotrichales	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
CMS1_k127_4529432_8	765913.ThidrDRAFT_1312	1.639e-73	252.0	COG1051@1|root,COG1051@2|Bacteria,1REBW@1224|Proteobacteria,1S3XB@1236|Gammaproteobacteria,1WYGA@135613|Chromatiales	135613|Chromatiales	F	Nudix N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX,Nudix_N_2
CMS1_k127_4529432_9	472759.Nhal_2580	3.095e-59	216.0	COG2755@1|root,COG2755@2|Bacteria,1RCXZ@1224|Proteobacteria,1S3QU@1236|Gammaproteobacteria,1WY36@135613|Chromatiales	135613|Chromatiales	E	PFAM lipolytic protein G-D-S-L family	-	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL_2
CMS1_k127_4529432_6	1384056.N787_02440	6.666e-84	285.0	COG4181@1|root,COG4181@2|Bacteria,1MXG9@1224|Proteobacteria,1RMG1@1236|Gammaproteobacteria,1X623@135614|Xanthomonadales	135614|Xanthomonadales	Q	ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
CMS1_k127_4529432_0	472759.Nhal_2578	1.892e-230	739.0	COG3127@1|root,COG3127@2|Bacteria,1MU9R@1224|Proteobacteria,1RM8Y@1236|Gammaproteobacteria,1WX8V@135613|Chromatiales	135613|Chromatiales	Q	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
CMS1_k127_4529432_14	1220534.B655_0574	1.435e-32	130.0	COG0662@1|root,arCOG03003@2157|Archaea,2Y1J0@28890|Euryarchaeota	28890|Euryarchaeota	G	PFAM Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
CMS1_k127_4529432_3	765912.Thimo_1839	1.043e-139	452.0	COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,1RMMS@1236|Gammaproteobacteria,1WWRK@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
CMS1_k127_4529432_11	765912.Thimo_0453	1.772e-50	182.0	COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,1S3VP@1236|Gammaproteobacteria,1WY9X@135613|Chromatiales	135613|Chromatiales	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
CMS1_k127_4529432_15	502025.Hoch_6530	9.599e-28	117.0	2CGNA@1|root,3301B@2|Bacteria,1N74P@1224|Proteobacteria,42VID@68525|delta/epsilon subdivisions,2WRHN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Yippee-Mis18
CMS1_k127_4529432_7	207559.Dde_0751	6.543e-75	260.0	COG0730@1|root,COG0730@2|Bacteria,1R3V4@1224|Proteobacteria,42NFH@68525|delta/epsilon subdivisions,2WITT@28221|Deltaproteobacteria,2M8DG@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
CMS1_k127_4529432_4	1049564.TevJSym_ac01550	6.148e-136	456.0	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,1RMS8@1236|Gammaproteobacteria,1J4MZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	slt	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009274,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	iETEC_1333.ETEC_4747,iPC815.YPO0452	SLT,SLT_L
CMS1_k127_4529432_5	713586.KB900536_gene2508	1.635e-109	364.0	COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria,1RNS7@1236|Gammaproteobacteria,1WXE7@135613|Chromatiales	135613|Chromatiales	GM	NAD-dependent epimerase dehydratase	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	Epimerase,NAD_binding_10
CMS1_k127_4529432_2	472759.Nhal_0230	2.663e-167	534.0	COG0617@1|root,COG0617@2|Bacteria,1MU2X@1224|Proteobacteria,1RPFJ@1236|Gammaproteobacteria,1WWKR@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases	cca	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
CMS1_k127_4529432_13	1249627.D779_3015	1.367e-40	156.0	COG1846@1|root,COG1846@2|Bacteria,1RF8X@1224|Proteobacteria,1S4RW@1236|Gammaproteobacteria,1WZMS@135613|Chromatiales	135613|Chromatiales	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
CMS1_k127_4529432_12	1283300.ATXB01000002_gene3206	2.221e-49	181.0	COG0454@1|root,COG0456@2|Bacteria,1RHB7@1224|Proteobacteria,1S3TD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	L-2,4-diaminobutyric acid acetyltransferase	ectA	-	2.3.1.178	ko:K06718	ko00260,ko01100,ko01120,map00260,map01100,map01120	M00033	R06978	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
CMS1_k127_4529432_1	118005.AWNK01000006_gene1245	3.105e-205	645.0	COG0160@1|root,COG0160@2|Bacteria	2|Bacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	ectB	-	2.6.1.76	ko:K00836	ko00260,ko01100,ko01120,ko01210,ko01230,map00260,map01100,map01120,map01210,map01230	M00033	R06977	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
CMS1_k127_4529432_10	717231.Flexsi_0826	1.096e-51	188.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	ectC	-	4.2.1.108	ko:K06720	ko00260,ko01100,ko01120,map00260,map01100,map01120	M00033	R06979	RC01729	ko00000,ko00001,ko00002,ko01000	-	-	-	Ectoine_synth
CMS1_k127_4529432_16	742159.HMPREF0004_2491	8.891e-20	93.0	COG5285@1|root,COG5285@2|Bacteria,1MWD5@1224|Proteobacteria,2VM24@28216|Betaproteobacteria,3T1BF@506|Alcaligenaceae	28216|Betaproteobacteria	Q	Ectoine hydroxylase	thpD	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016705,GO:0016706,GO:0019752,GO:0032787,GO:0042399,GO:0042400,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0051213,GO:0055114,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	1.14.11.55	ko:K10674	ko00260,ko01120,map00260,map01120	-	R08050	RC00661	ko00000,ko00001,ko01000	-	-	-	PhyH
CMS1_k127_454669_12	1499967.BAYZ01000074_gene2101	4.126e-25	122.0	COG1807@1|root,COG1807@2|Bacteria,2NP0P@2323|unclassified Bacteria	2|Bacteria	M	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT_2
CMS1_k127_454669_0	765911.Thivi_0796	1.35e-212	696.0	COG4262@1|root,COG4262@2|Bacteria,1RFZS@1224|Proteobacteria,1S1NP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_454669_10	1318628.MARLIPOL_01325	3.864e-33	134.0	COG4969@1|root,COG4969@2|Bacteria,1N7EQ@1224|Proteobacteria,1SCES@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	Belongs to the N-Me-Phe pilin family	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,Pilin
CMS1_k127_454669_5	395493.BegalDRAFT_1580	2.678e-79	289.0	COG0457@1|root,COG0457@2|Bacteria,1R50I@1224|Proteobacteria,1RSP6@1236|Gammaproteobacteria,462D9@72273|Thiotrichales	72273|Thiotrichales	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_454669_3	83406.HDN1F_30910	8.111e-105	347.0	COG0463@1|root,COG0463@2|Bacteria,1MXC1@1224|Proteobacteria,1RRHP@1236|Gammaproteobacteria,1J9RZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS1_k127_454669_4	56780.SYN_00817	1.83e-99	340.0	COG0438@1|root,COG0438@2|Bacteria,1R564@1224|Proteobacteria,42RYD@68525|delta/epsilon subdivisions,2X5EZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS1_k127_454669_8	1282362.AEAC466_18310	9.698e-61	216.0	COG3449@1|root,COG3449@2|Bacteria,1RF2U@1224|Proteobacteria,2UBIJ@28211|Alphaproteobacteria,2KGM8@204458|Caulobacterales	204458|Caulobacterales	L	SOUL heme-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SOUL
CMS1_k127_454669_6	1123393.KB891316_gene1129	9.433e-71	243.0	COG0693@1|root,COG0693@2|Bacteria,1N7T2@1224|Proteobacteria,2VS5Q@28216|Betaproteobacteria,1KSPI@119069|Hydrogenophilales	119069|Hydrogenophilales	S	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
CMS1_k127_454669_2	857087.Metme_0275	1.013e-165	533.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,1XEI9@135618|Methylococcales	135618|Methylococcales	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
CMS1_k127_454669_7	1121374.KB891575_gene934	1.026e-68	250.0	COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,1RPQP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	peptidase	envC	GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CMS1_k127_454669_1	1049564.TevJSym_at00260	1.151e-202	642.0	COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,1RMJE@1236|Gammaproteobacteria,1J4GC@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030145,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046537,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	iECSE_1348.ECSE_3895,iJN746.PP_5056	Metalloenzyme,Phosphodiest,iPGM_N
CMS1_k127_454669_11	395493.BegalDRAFT_1767	5.2e-28	118.0	COG0607@1|root,COG0607@2|Bacteria,1MZ83@1224|Proteobacteria,1S8ZI@1236|Gammaproteobacteria,4614X@72273|Thiotrichales	72273|Thiotrichales	P	PFAM Rhodanese-like	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
CMS1_k127_454669_9	472759.Nhal_0026	2.633e-44	169.0	COG1952@1|root,COG1952@2|Bacteria,1RI75@1224|Proteobacteria,1S62H@1236|Gammaproteobacteria,1WY33@135613|Chromatiales	135613|Chromatiales	U	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA	secB	-	-	ko:K03071	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03110	3.A.5	-	-	SecB
CMS1_k127_4579013_1	1123368.AUIS01000026_gene1451	2.017e-176	565.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,1RPRC@1236|Gammaproteobacteria,2NBZ8@225057|Acidithiobacillales	225057|Acidithiobacillales	J	arginyl-tRNA aminoacylation	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
CMS1_k127_4579013_21	713586.KB900536_gene2406	5.583e-27	119.0	COG3087@1|root,COG3087@2|Bacteria,1RCC0@1224|Proteobacteria,1SBGX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	Sporulation related domain	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
CMS1_k127_4579013_22	395493.BegalDRAFT_0458	5.858e-25	108.0	COG3437@1|root,COG3437@2|Bacteria	2|Bacteria	T	response regulator, receiver	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	EAL,GGDEF,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg,SpoIIE
CMS1_k127_4579013_6	395493.BegalDRAFT_0459	3.545e-122	398.0	COG1235@1|root,COG1235@2|Bacteria,1NW4Z@1224|Proteobacteria,1RPS3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
CMS1_k127_4579013_23	626887.J057_10246	2.736e-14	74.0	COG2104@1|root,COG2104@2|Bacteria,1N8P3@1224|Proteobacteria,1SCZM@1236|Gammaproteobacteria,46922@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	COG2104 Sulfur transfer protein involved in thiamine biosynthesis	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
CMS1_k127_4579013_4	631362.Thi970DRAFT_01405	3.384e-126	407.0	COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,1RMPD@1236|Gammaproteobacteria,1WW65@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
CMS1_k127_4579013_12	323848.Nmul_A0069	3.163e-75	260.0	COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,2VJN2@28216|Betaproteobacteria,371VV@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	-	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
CMS1_k127_4579013_14	237609.PSAKL28_02800	1.53e-72	250.0	COG1011@1|root,COG1011@2|Bacteria,1NH15@1224|Proteobacteria,1RP27@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Hydrolase	yrfG	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008477,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016798,GO:0016799,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050483,GO:0050484	3.1.3.5	ko:K20881	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2,Hydrolase
CMS1_k127_4579013_8	395493.BegalDRAFT_2882	2.071e-96	322.0	COG1218@1|root,COG1218@2|Bacteria,1N0GY@1224|Proteobacteria,1RP5A@1236|Gammaproteobacteria,460I9@72273|Thiotrichales	72273|Thiotrichales	P	Inositol monophosphatase family	-	-	3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Inositol_P
CMS1_k127_4579013_3	870187.Thini_2985	1.775e-135	439.0	COG5345@1|root,COG5345@2|Bacteria,1MWVH@1224|Proteobacteria,1RP5X@1236|Gammaproteobacteria,4625H@72273|Thiotrichales	72273|Thiotrichales	S	protein conserved in bacteria (DUF2333)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2333
CMS1_k127_4579013_24	1121104.AQXH01000005_gene171	1.275e-12	75.0	2CD87@1|root,346ZF@2|Bacteria,4P66A@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4579013_20	472759.Nhal_0917	9.778e-35	138.0	COG2924@1|root,COG2924@2|Bacteria,1MZ2V@1224|Proteobacteria,1S964@1236|Gammaproteobacteria,1WYU9@135613|Chromatiales	135613|Chromatiales	CO	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Iron_traffic
CMS1_k127_4579013_5	1121937.AUHJ01000013_gene822	1.779e-125	412.0	COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,1RMBT@1236|Gammaproteobacteria,4642P@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	COG1194 A G-specific DNA glycosylase	mutY	GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
CMS1_k127_4579013_26	1122604.JONR01000012_gene3411	9.24e-08	61.0	2DQ0C@1|root,33473@2|Bacteria,1NAM4@1224|Proteobacteria,1SCY6@1236|Gammaproteobacteria,1XB49@135614|Xanthomonadales	135614|Xanthomonadales	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
CMS1_k127_4579013_13	754477.Q7C_791	3.544e-73	282.0	COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,1RPFM@1236|Gammaproteobacteria,45ZVU@72273|Thiotrichales	72273|Thiotrichales	M	PFAM AsmA family	-	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA
CMS1_k127_4579013_18	1283300.ATXB01000001_gene23	5.946e-41	176.0	COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,1RPFM@1236|Gammaproteobacteria,1XE8Z@135618|Methylococcales	135618|Methylococcales	M	AsmA family	-	-	-	-	-	-	-	-	-	-	-	-	AsmA
CMS1_k127_4579013_0	1396858.Q666_00180	3.454e-197	625.0	COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,1RMA3@1236|Gammaproteobacteria,4644I@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
CMS1_k127_4579013_9	1049564.TevJSym_bb00370	6.804e-88	302.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,1RQDA@1236|Gammaproteobacteria,1J5V1@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	signal transduction protein with a C-terminal ATPase domain	algZ	-	2.7.13.3	ko:K08082	ko02020,map02020	M00493	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	His_kinase
CMS1_k127_4579013_15	1121013.P873_08825	6.15e-63	226.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,1RMJJ@1236|Gammaproteobacteria,1X3HP@135614|Xanthomonadales	135614|Xanthomonadales	KT	Response regulator of the LytR AlgR family	-	-	-	ko:K08083	ko02020,map02020	M00493	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	LytTR,Response_reg
CMS1_k127_4579013_2	754476.Q7A_34	4.059e-166	533.0	COG0342@1|root,COG0342@2|Bacteria,1MVFS@1224|Proteobacteria,1RYCF@1236|Gammaproteobacteria,461NY@72273|Thiotrichales	72273|Thiotrichales	U	glutamate--cysteine ligase	-	-	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	GshA
CMS1_k127_4579013_16	267608.RSc0451	1.626e-62	218.0	2BYAC@1|root,32R5Y@2|Bacteria,1NBTP@1224|Proteobacteria,2W2XI@28216|Betaproteobacteria,1KDKD@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4579013_17	1283300.ATXB01000002_gene2896	1.382e-50	181.0	COG2020@1|root,COG2020@2|Bacteria,1PK65@1224|Proteobacteria,1TI8M@1236|Gammaproteobacteria,1XGS2@135618|Methylococcales	135618|Methylococcales	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
CMS1_k127_4579013_10	156889.Mmc1_1921	9.137e-86	307.0	COG0515@1|root,COG1262@1|root,COG3170@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,COG3170@2|Bacteria,1PJRR@1224|Proteobacteria,2U625@28211|Alphaproteobacteria	28211|Alphaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	DUF4189,PG_binding_1,Pkinase,WD40
CMS1_k127_4579013_11	335543.Sfum_0454	1.507e-80	274.0	COG0586@1|root,COG0586@2|Bacteria,1MX4M@1224|Proteobacteria,42RMJ@68525|delta/epsilon subdivisions,2WNP9@28221|Deltaproteobacteria,2MRKX@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
CMS1_k127_4579013_19	395493.BegalDRAFT_1783	6.603e-36	142.0	COG3198@1|root,COG3198@2|Bacteria,1N75J@1224|Proteobacteria,1SC87@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	ccoH	-	-	ko:K09926	-	-	-	-	ko00000	-	-	-	FixH
CMS1_k127_4579013_7	395493.BegalDRAFT_2182	1.77e-116	382.0	COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,1RMDI@1236|Gammaproteobacteria,4601I@72273|Thiotrichales	72273|Thiotrichales	C	TIGRFAM cytochrome c oxidase accessory protein FixG	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
CMS1_k127_4609828_2	1121033.AUCF01000012_gene984	6.812e-137	452.0	COG3203@1|root,COG3203@2|Bacteria,1MXEB@1224|Proteobacteria,2U8WW@28211|Alphaproteobacteria,2JSKJ@204441|Rhodospirillales	204441|Rhodospirillales	M	Protein of unknown function (DUF1302)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1302
CMS1_k127_4609828_1	1121033.AUCF01000012_gene983	4.413e-171	548.0	28H52@1|root,2Z7HQ@2|Bacteria,1MXTF@1224|Proteobacteria,2U2TN@28211|Alphaproteobacteria,2JR36@204441|Rhodospirillales	204441|Rhodospirillales	S	Protein of unknown function (DUF1329)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1329
CMS1_k127_4609828_4	391615.ABSJ01000054_gene1378	2.614e-67	243.0	COG4447@1|root,COG4447@2|Bacteria,1RCNG@1224|Proteobacteria,1S4IP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Photosynthesis system II assembly factor YCF48	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
CMS1_k127_4609828_0	391615.ABSJ01000054_gene1379	2.832e-257	815.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RN01@1236|Gammaproteobacteria,1J5BG@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
CMS1_k127_4609828_3	187272.Mlg_2638	3.538e-81	285.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,1RMZ5@1236|Gammaproteobacteria,1WVUX@135613|Chromatiales	135613|Chromatiales	M	Lipid A biosynthesis	lpxL	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
CMS1_k127_4609828_8	1206735.BAGG01000019_gene805	0.0006341	44.0	COG1961@1|root,COG1961@2|Bacteria,2GNGI@201174|Actinobacteria,4FVZ0@85025|Nocardiaceae	201174|Actinobacteria	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
CMS1_k127_4609828_5	1161401.ASJA01000004_gene2303	8.667e-32	140.0	COG1404@1|root,COG2931@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2TRVY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,P_proprotein,Peptidase_S8
CMS1_k127_4609828_6	545696.HOLDEFILI_02195	7.517e-06	48.0	COG1605@1|root,COG1605@2|Bacteria	2|Bacteria	E	Chorismate mutase	aroK	-	1.1.1.25,2.7.1.71,5.4.99.5	ko:K00014,ko:K00891,ko:K04092,ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022,M00024,M00025	R01715,R02412,R02413	RC00002,RC00078,RC00206,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,SKI
CMS1_k127_4609828_7	1129794.C427_2371	2.191e-05	47.0	COG3316@1|root,COG3316@2|Bacteria,1MWZ2@1224|Proteobacteria,1RRC2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase and inactivated derivatives	-	-	-	ko:K07498	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS240
CMS1_k127_464012_2	472759.Nhal_2676	5.222e-98	337.0	COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,1RN14@1236|Gammaproteobacteria,1WWPM@135613|Chromatiales	135613|Chromatiales	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
CMS1_k127_464012_1	1283300.ATXB01000001_gene2451	1.025e-137	445.0	COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,1RNN8@1236|Gammaproteobacteria,1XE5H@135618|Methylococcales	135618|Methylococcales	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
CMS1_k127_464012_0	472759.Nhal_2673	4.873e-262	825.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,1RP0K@1236|Gammaproteobacteria,1WVZ3@135613|Chromatiales	135613|Chromatiales	L	DNA polymerase III alpha subunit	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,Intein_splicing,LAGLIDADG_3,PHP,tRNA_anti-codon
CMS1_k127_4680449_3	396588.Tgr7_2119	4.329e-106	351.0	COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,1RMTC@1236|Gammaproteobacteria,1WWE3@135613|Chromatiales	135613|Chromatiales	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
CMS1_k127_4680449_1	713586.KB900536_gene926	1.388e-230	721.0	COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,1RMTC@1236|Gammaproteobacteria,1WWE3@135613|Chromatiales	135613|Chromatiales	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
CMS1_k127_4680449_0	1149133.ppKF707_1915	7.641e-297	923.0	COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,1RMCI@1236|Gammaproteobacteria,1YCUV@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parE	GO:0000819,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0022402,GO:0030541,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0098813,GO:0140097,GO:1901360	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
CMS1_k127_4680449_5	2340.JV46_02690	3.673e-73	251.0	COG0247@1|root,COG0247@2|Bacteria,1RF02@1224|Proteobacteria,1S302@1236|Gammaproteobacteria,1J9N9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Protein of unknown function (DUF3501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3501
CMS1_k127_4680449_2	395493.BegalDRAFT_2790	5.196e-204	643.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,1RQ9M@1236|Gammaproteobacteria,4620M@72273|Thiotrichales	72273|Thiotrichales	C	Cysteine-rich domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG
CMS1_k127_4680449_4	1121878.AUGL01000014_gene1630	1.692e-76	258.0	COG1592@1|root,COG1592@2|Bacteria,1R9WG@1224|Proteobacteria,1S25G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	PFAM Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
CMS1_k127_4680449_6	227377.CBU_0468	6.946e-18	86.0	COG1722@1|root,COG1722@2|Bacteria,1N72V@1224|Proteobacteria,1SC7N@1236|Gammaproteobacteria,1JF8E@118969|Legionellales	118969|Legionellales	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
CMS1_k127_4680449_7	382464.ABSI01000010_gene3454	2.848e-05	49.0	COG0142@1|root,COG0142@2|Bacteria,46S62@74201|Verrucomicrobia,2IU28@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Polyprenyl synthetase	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
CMS1_k127_4719928_2	713586.KB900536_gene2710	2.46e-54	195.0	COG2259@1|root,COG2259@2|Bacteria,1RDRZ@1224|Proteobacteria,1SA8P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	DoxX family	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
CMS1_k127_4719928_4	1123399.AQVE01000009_gene3059	7.664e-31	122.0	COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,1RP9Z@1236|Gammaproteobacteria,45ZTF@72273|Thiotrichales	72273|Thiotrichales	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
CMS1_k127_4719928_0	288000.BBta_7293	4.091e-161	521.0	COG0280@1|root,COG0280@2|Bacteria,1QTXP@1224|Proteobacteria,2TQYT@28211|Alphaproteobacteria,3JTVX@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Phosphate acetyl/butaryl transferase	pta	-	2.3.1.19,2.3.1.8	ko:K00625,ko:K00634	ko00430,ko00620,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00650,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921,R01174	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	MaoC_dehydratas,PTA_PTB
CMS1_k127_4719928_1	1219045.BV98_000685	3.803e-127	419.0	COG0282@1|root,COG0282@2|Bacteria,1MW61@1224|Proteobacteria,2TQQQ@28211|Alphaproteobacteria,2K34Z@204457|Sphingomonadales	204457|Sphingomonadales	H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
CMS1_k127_4719928_3	231434.JQJH01000012_gene2881	7.102e-51	190.0	COG3243@1|root,COG3243@2|Bacteria,1MUNE@1224|Proteobacteria,2TRK4@28211|Alphaproteobacteria,3NAQF@45404|Beijerinckiaceae	28211|Alphaproteobacteria	I	Protein of unknown function (DUF3141)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3141
CMS1_k127_4753497_4	315730.BcerKBAB4_4927	7.018e-41	154.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,4HAKI@91061|Bacilli,1ZAZB@1386|Bacillus	91061|Bacilli	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0044877,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
CMS1_k127_4753497_2	187272.Mlg_1840	3.249e-139	445.0	COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,1RMGQ@1236|Gammaproteobacteria,1WWZU@135613|Chromatiales	135613|Chromatiales	M	3-deoxy-D-manno-octulosonic acid 8-phosphate synthase	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
CMS1_k127_4753497_1	396588.Tgr7_1182	8.634e-272	845.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,1RM92@1236|Gammaproteobacteria,1WWJ8@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
CMS1_k127_4753497_3	1123257.AUFV01000007_gene273	3.795e-74	259.0	COG0697@1|root,COG0697@2|Bacteria,1MZXM@1224|Proteobacteria,1S44I@1236|Gammaproteobacteria,1X3DU@135614|Xanthomonadales	135614|Xanthomonadales	EG	Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
CMS1_k127_4753497_0	1000565.METUNv1_00587	1.43e-303	936.0	COG2759@1|root,COG2759@2|Bacteria,1MUR8@1224|Proteobacteria,2VKR6@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Belongs to the formate--tetrahydrofolate ligase family	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
CMS1_k127_4804550_7	1380387.JADM01000002_gene1914	3.846e-53	191.0	COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,1RMUQ@1236|Gammaproteobacteria,1XH3J@135619|Oceanospirillales	135619|Oceanospirillales	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
CMS1_k127_4804550_3	323261.Noc_2807	6.183e-177	558.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,1WXC0@135613|Chromatiales	135613|Chromatiales	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapA	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
CMS1_k127_4804550_0	472759.Nhal_3450	1.557e-314	974.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,1RMWP@1236|Gammaproteobacteria,1WVWH@135613|Chromatiales	135613|Chromatiales	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
CMS1_k127_4804550_8	1541065.JRFE01000006_gene4801	7.033e-26	109.0	COG0454@1|root,COG0456@2|Bacteria,1GQ8F@1117|Cyanobacteria	1117|Cyanobacteria	K	Domain of unknown function (DUF4915)	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,DUF4915
CMS1_k127_4804550_6	637390.AFOH01000025_gene1036	1.798e-53	194.0	COG0449@1|root,COG0449@2|Bacteria,1RGWX@1224|Proteobacteria,1SPE9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	ORF6N domain	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N
CMS1_k127_4804550_5	1163408.UU9_11673	2.659e-57	209.0	COG1943@1|root,COG1943@2|Bacteria,1P19I@1224|Proteobacteria,1RQYI@1236|Gammaproteobacteria,1X5ID@135614|Xanthomonadales	135614|Xanthomonadales	L	COG1943 Transposase and inactivated derivatives	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
CMS1_k127_4804550_4	1249627.D779_1391	1.282e-85	286.0	COG1225@1|root,COG1225@2|Bacteria,1R9YF@1224|Proteobacteria,1S37E@1236|Gammaproteobacteria,1WWWB@135613|Chromatiales	135613|Chromatiales	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
CMS1_k127_4804550_2	870187.Thini_2563	1.698e-188	599.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,1RNV6@1236|Gammaproteobacteria,45ZZ4@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
CMS1_k127_4804550_1	472759.Nhal_0523	4.871e-245	760.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,1RMW8@1236|Gammaproteobacteria,1WVY5@135613|Chromatiales	135613|Chromatiales	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
CMS1_k127_485654_2	748247.AZKH_0153	3.152e-22	99.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,2VHQQ@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (cpa2) transporter (TC 2.A.37) family	kefC	-	-	ko:K03455,ko:K11745,ko:K11747	-	-	-	-	ko00000,ko02000	2.A.37,2.A.37.1.1,2.A.37.1.2	-	-	Na_H_Exchanger,TrkA_N
CMS1_k127_485654_1	1283300.ATXB01000001_gene536	4.431e-37	147.0	COG3212@1|root,COG3212@2|Bacteria,1N2PN@1224|Proteobacteria,1T8Q0@1236|Gammaproteobacteria,1XFJ1@135618|Methylococcales	135618|Methylococcales	S	Peptidase propeptide and YPEB domain	-	-	-	-	-	-	-	-	-	-	-	-	PepSY
CMS1_k127_485654_0	1122194.AUHU01000004_gene1491	2.833e-65	226.0	COG3484@1|root,COG3484@2|Bacteria,1N057@1224|Proteobacteria,1RRR0@1236|Gammaproteobacteria,466NX@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	PFAM 20S proteasome, A and B subunits	-	-	-	ko:K07395	-	-	-	-	ko00000	-	-	-	Proteasome
CMS1_k127_4869291_23	323261.Noc_2464	2.206e-56	206.0	COG3026@1|root,COG3026@2|Bacteria,1MUQ8@1224|Proteobacteria,1RNF3@1236|Gammaproteobacteria,1WWVY@135613|Chromatiales	135613|Chromatiales	T	PFAM MucB RseB	-	-	-	ko:K03598	-	-	-	-	ko00000,ko03021	-	-	-	MucB_RseB,MucB_RseB_C
CMS1_k127_4869291_4	396588.Tgr7_1087	6.366e-167	542.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1WWWR@135613|Chromatiales	135613|Chromatiales	M	Belongs to the peptidase S1C family	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
CMS1_k127_4869291_33	1266909.AUAG01000014_gene2255	4.667e-12	70.0	COG3118@1|root,COG3118@2|Bacteria	2|Bacteria	O	belongs to the thioredoxin family	trxA	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	DUF836,Thioredoxin
CMS1_k127_4869291_0	395493.BegalDRAFT_2077	7.263e-287	891.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,1RPFB@1236|Gammaproteobacteria,45ZWP@72273|Thiotrichales	72273|Thiotrichales	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
CMS1_k127_4869291_15	396588.Tgr7_1090	2.807e-90	308.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,1RMHI@1236|Gammaproteobacteria,1WXAU@135613|Chromatiales	135613|Chromatiales	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
CMS1_k127_4869291_31	935863.AWZR01000006_gene1239	1.079e-13	76.0	COG4969@1|root,COG4969@2|Bacteria,1N71K@1224|Proteobacteria,1SCYD@1236|Gammaproteobacteria,1X8J8@135614|Xanthomonadales	135614|Xanthomonadales	NU	Domain of unknown function (DUF4845)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4845
CMS1_k127_4869291_19	1122212.AULO01000008_gene1573	2.685e-71	247.0	COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,1RN0C@1236|Gammaproteobacteria,1XHKG@135619|Oceanospirillales	135619|Oceanospirillales	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
CMS1_k127_4869291_10	247633.GP2143_08214	2.441e-95	320.0	COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,1RN3A@1236|Gammaproteobacteria,1J4EI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009898,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019538,GO:0019843,GO:0019897,GO:0019898,GO:0022613,GO:0031234,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0036211,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044877,GO:0046777,GO:0070181,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1901564	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
CMS1_k127_4869291_24	472759.Nhal_2438	4.449e-53	196.0	COG1381@1|root,COG1381@2|Bacteria,1RHIC@1224|Proteobacteria,1RN8Y@1236|Gammaproteobacteria,1WY02@135613|Chromatiales	135613|Chromatiales	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
CMS1_k127_4869291_14	187272.Mlg_1350	3.93e-92	308.0	COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,1RMS5@1236|Gammaproteobacteria,1WXFG@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	-	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
CMS1_k127_4869291_28	292415.Tbd_0728	5.932e-28	118.0	COG0736@1|root,COG0736@2|Bacteria,1MZBF@1224|Proteobacteria,2VT0P@28216|Betaproteobacteria,1KRUE@119069|Hydrogenophilales	119069|Hydrogenophilales	I	4'-phosphopantetheinyl transferase superfamily	-	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
CMS1_k127_4869291_1	472759.Nhal_2825	3.38e-226	711.0	COG4108@1|root,COG4108@2|Bacteria,1MU7X@1224|Proteobacteria,1RMFT@1236|Gammaproteobacteria,1WX2I@135613|Chromatiales	135613|Chromatiales	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
CMS1_k127_4869291_2	765914.ThisiDRAFT_2334	1.758e-216	696.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMDS@1236|Gammaproteobacteria,1WXN6@135613|Chromatiales	135613|Chromatiales	J	Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs	rne	-	3.1.26.12	ko:K08300	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
CMS1_k127_4869291_16	472759.Nhal_0508	3.77e-90	306.0	COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,1RPAN@1236|Gammaproteobacteria,1WW19@135613|Chromatiales	135613|Chromatiales	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.24	ko:K06179	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
CMS1_k127_4869291_8	1266925.JHVX01000004_gene1115	3.684e-109	363.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,2VH94@28216|Betaproteobacteria,3727I@32003|Nitrosomonadales	28216|Betaproteobacteria	OU	Peptidase family S49	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
CMS1_k127_4869291_20	396588.Tgr7_1917	6.507e-64	227.0	COG0424@1|root,COG0424@2|Bacteria,1RDA9@1224|Proteobacteria,1S3TQ@1236|Gammaproteobacteria,1WX51@135613|Chromatiales	135613|Chromatiales	D	Maf-like protein	-	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
CMS1_k127_4869291_32	1268239.PALB_30870	1.699e-13	79.0	COG1399@1|root,COG1399@2|Bacteria,1PGKW@1224|Proteobacteria,1RRK3@1236|Gammaproteobacteria,2Q0M1@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	metal-binding, possibly nucleic acid-binding protein	yceD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
CMS1_k127_4869291_29	1335757.SPICUR_04615	9.118e-22	95.0	COG0333@1|root,COG0333@2|Bacteria,1N6RF@1224|Proteobacteria,1SC9G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
CMS1_k127_4869291_6	243233.MCA2004	2.857e-128	418.0	COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,1RM7R@1236|Gammaproteobacteria,1XDYY@135618|Methylococcales	135618|Methylococcales	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
CMS1_k127_4869291_5	2340.JV46_14790	8.196e-157	499.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,1RNIR@1236|Gammaproteobacteria,1J5D9@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iAF1260.b1091,iAPECO1_1312.APECO1_172,iBWG_1329.BWG_0939,iE2348C_1286.E2348C_1183,iEC55989_1330.EC55989_1203,iECABU_c1320.ECABU_c13040,iECDH10B_1368.ECDH10B_1163,iECDH1ME8569_1439.ECDH1ME8569_1026,iECED1_1282.ECED1_1234,iECH74115_1262.ECH74115_1470,iECIAI39_1322.ECIAI39_2070,iECO103_1326.ECO103_1136,iECO111_1330.ECO111_1368,iECO26_1355.ECO26_1424,iECOK1_1307.ECOK1_1198,iECP_1309.ECP_1083,iECS88_1305.ECS88_1105,iECSP_1301.ECSP_1392,iECW_1372.ECW_m1199,iECs_1301.ECs1469,iEKO11_1354.EKO11_2743,iETEC_1333.ETEC_1156,iEcDH1_1363.EcDH1_2556,iEcE24377_1341.EcE24377A_1212,iEcSMS35_1347.EcSMS35_2036,iG2583_1286.G2583_1351,iJO1366.b1091,iJR904.b1091,iLF82_1304.LF82_0609,iNRG857_1313.NRG857_05260,iSSON_1240.SSON_1111,iSbBS512_1146.SbBS512_E2233,iUMN146_1321.UM146_11870,iUMNK88_1353.UMNK88_1361,iUTI89_1310.UTI89_C1216,iWFL_1372.ECW_m1199,iY75_1357.Y75_RS05700,iZ_1308.Z1730,ic_1306.c1360	ACP_syn_III,ACP_syn_III_C
CMS1_k127_4869291_7	1166130.H650_24555	6.866e-110	363.0	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,1RNH3@1236|Gammaproteobacteria,3WZY0@547|Enterobacter	1236|Gammaproteobacteria	I	malonyl CoA-acyl carrier protein transacylase	fabD	GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iEcE24377_1341.EcE24377A_1213,iJN746.PP_1913,iPC815.YPO1598	Acyl_transf_1
CMS1_k127_4869291_17	349124.Hhal_1233	3.557e-89	301.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,1RMBB@1236|Gammaproteobacteria,1WXR9@135613|Chromatiales	135613|Chromatiales	IQ	PFAM Short-chain dehydrogenase reductase SDR	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS1_k127_4869291_27	1260251.SPISAL_04060	8.913e-35	134.0	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,1S8X4@1236|Gammaproteobacteria,1WYUG@135613|Chromatiales	135613|Chromatiales	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
CMS1_k127_4869291_3	754477.Q7C_2684	8.775e-196	617.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,45ZQ6@72273|Thiotrichales	72273|Thiotrichales	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
CMS1_k127_4869291_18	472759.Nhal_3120	8.541e-84	288.0	COG0115@1|root,COG0115@2|Bacteria,1MZAK@1224|Proteobacteria,1RPPG@1236|Gammaproteobacteria,1WXUQ@135613|Chromatiales	135613|Chromatiales	EH	PFAM Aminotransferase, class IV	-	-	4.1.3.38	ko:K02619	ko00790,map00790	-	R05553	RC01843,RC02148	ko00000,ko00001,ko01000	-	-	-	Aminotran_4
CMS1_k127_4869291_11	631362.Thi970DRAFT_03609	7.548e-95	323.0	COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,1RMWD@1236|Gammaproteobacteria,1WWK3@135613|Chromatiales	135613|Chromatiales	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
CMS1_k127_4869291_21	1122201.AUAZ01000017_gene2913	3.656e-59	211.0	COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,1S26C@1236|Gammaproteobacteria,466N6@72275|Alteromonadaceae	1236|Gammaproteobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iECABU_c1320.ECABU_c13120,ic_1306.c1370	Thymidylate_kin
CMS1_k127_4869291_22	395493.BegalDRAFT_1778	9.094e-58	213.0	COG0470@1|root,COG0470@2|Bacteria,1MY1W@1224|Proteobacteria,1RNYA@1236|Gammaproteobacteria,460WJ@72273|Thiotrichales	72273|Thiotrichales	L	TIGRFAM DNA polymerase III, delta	-	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
CMS1_k127_4869291_26	1123020.AUIE01000007_gene3443	1.025e-47	174.0	COG3215@1|root,COG3215@2|Bacteria,1RGWZ@1224|Proteobacteria,1S4YE@1236|Gammaproteobacteria,1YG5E@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	NU	PilZ domain	pilZ	-	-	ko:K02676	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilZ
CMS1_k127_4869291_13	472759.Nhal_3125	9.237e-94	314.0	COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,1RP6E@1236|Gammaproteobacteria,1WXA1@135613|Chromatiales	135613|Chromatiales	L	TIGRFAM hydrolase, TatD family	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
CMS1_k127_4869291_9	543913.D521_0650	4.124e-96	328.0	COG2114@1|root,COG2114@2|Bacteria,1PG87@1224|Proteobacteria,2W8ZT@28216|Betaproteobacteria,1KR50@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
CMS1_k127_4869291_12	1238182.C882_0582	2.332e-94	337.0	COG2982@1|root,COG2982@2|Bacteria,1MUAN@1224|Proteobacteria,2U26R@28211|Alphaproteobacteria,2JPQ3@204441|Rhodospirillales	204441|Rhodospirillales	M	AsmA family	-	-	-	ko:K07289,ko:K07290	-	-	-	-	ko00000	9.B.121	-	-	AsmA,AsmA_2
CMS1_k127_4869291_30	1328313.DS2_10267	6.758e-14	84.0	COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,1T0TB@1236|Gammaproteobacteria,46D17@72275|Alteromonadaceae	1236|Gammaproteobacteria	NU	COG3170 Tfp pilus assembly protein FimV	-	-	-	ko:K08086	-	-	-	-	ko00000	-	-	-	-
CMS1_k127_4869291_25	396588.Tgr7_1249	2.916e-49	193.0	COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,1RMM5@1236|Gammaproteobacteria,1WVVA@135613|Chromatiales	135613|Chromatiales	NU	FimV C-terminal	-	-	-	ko:K08086	-	-	-	-	ko00000	-	-	-	TPR_19
CMS1_k127_4879407_5	1034943.BN1094_01982	6.208e-31	129.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,1RPRC@1236|Gammaproteobacteria,1JCE1@118969|Legionellales	118969|Legionellales	J	arginyl-tRNA aminoacylation	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
CMS1_k127_4879407_3	1469245.JFBG01000012_gene931	4.656e-86	292.0	COG0607@1|root,COG0607@2|Bacteria,1REGB@1224|Proteobacteria,1S580@1236|Gammaproteobacteria,1X2R1@135613|Chromatiales	135613|Chromatiales	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
CMS1_k127_4879407_1	472759.Nhal_0019	6.42e-223	714.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,1RPZ7@1236|Gammaproteobacteria,1WX60@135613|Chromatiales	135613|Chromatiales	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
CMS1_k127_4879407_0	105559.Nwat_0344	3.027e-291	914.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,1RM7J@1236|Gammaproteobacteria,1WWH1@135613|Chromatiales	135613|Chromatiales	M	TIGRFAM penicillin-binding protein, 1A	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	PCB_OB,Transgly,Transpeptidase
CMS1_k127_4879407_2	472759.Nhal_3891	5.479e-132	429.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,1RN8S@1236|Gammaproteobacteria,1WXGR@135613|Chromatiales	135613|Chromatiales	NU	TIGRFAM type IV pilus assembly protein PilM	-	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
CMS1_k127_4879407_4	1283300.ATXB01000001_gene2122	5.91e-47	174.0	COG3166@1|root,COG3166@2|Bacteria,1RF1S@1224|Proteobacteria,1S3S0@1236|Gammaproteobacteria,1XF1T@135618|Methylococcales	135618|Methylococcales	NU	PFAM Fimbrial assembly	-	-	-	ko:K02663	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilN
CMS1_k127_4900702_2	396588.Tgr7_1253	7.138e-143	456.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,1RP4D@1236|Gammaproteobacteria,1WW9F@135613|Chromatiales	135613|Chromatiales	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
CMS1_k127_4900702_6	572477.Alvin_1600	6.663e-99	329.0	COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,1RMGN@1236|Gammaproteobacteria,1WXGF@135613|Chromatiales	135613|Chromatiales	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
CMS1_k127_4900702_3	1255043.TVNIR_1222	1.222e-128	416.0	COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,1RNDS@1236|Gammaproteobacteria,1WW2U@135613|Chromatiales	135613|Chromatiales	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
CMS1_k127_4900702_4	1123393.KB891316_gene1187	1.818e-118	396.0	COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,2VI0H@28216|Betaproteobacteria,1KSGF@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Mur ligase family, glutamate ligase domain	-	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
CMS1_k127_4900702_12	1198232.CYCME_1512	2.258e-24	109.0	COG3147@1|root,COG3147@2|Bacteria,1NGE3@1224|Proteobacteria,1SCGC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	dedD	-	-	ko:K03749	-	-	-	-	ko00000	-	-	-	SPOR
CMS1_k127_4900702_11	1198232.CYCME_1511	8.213e-25	110.0	COG1286@1|root,COG1286@2|Bacteria,1NF4G@1224|Proteobacteria,1RQ58@1236|Gammaproteobacteria,4618X@72273|Thiotrichales	72273|Thiotrichales	S	Colicin V production protein	-	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
CMS1_k127_4900702_0	243233.MCA2489	1.806e-234	736.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,1RMYA@1236|Gammaproteobacteria,1XETA@135618|Methylococcales	135618|Methylococcales	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,Pribosyltran
CMS1_k127_4900702_1	314278.NB231_00480	2.747e-207	657.0	COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,1SBE1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	COG2274 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	hlyB	-	-	ko:K11004	ko02010,ko03070,ko05133,map02010,map03070,map05133	M00325,M00575	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1.109.1,3.A.1.109.2	-	-	ABC_membrane,ABC_tran,Peptidase_C39
CMS1_k127_4900702_8	1049564.TevJSym_bj00240	3.955e-86	287.0	COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,1SBE1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	COG2274 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain	hlyB	-	-	ko:K11004	ko02010,ko03070,ko05133,map02010,map03070,map05133	M00325,M00575	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1.109.1,3.A.1.109.2	-	-	ABC_membrane,ABC_tran,Peptidase_C39
CMS1_k127_4900702_5	1049564.TevJSym_bj00230	6.103e-102	349.0	COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,1RNK4@1236|Gammaproteobacteria,1J4TZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	COG0845 Membrane-fusion protein	-	-	-	ko:K11003,ko:K12542	ko03070,ko05133,map03070,map05133	M00325,M00330,M00575	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1.109.4,8.A.1,8.A.1.3.1,8.A.1.3.2	-	-	Biotin_lipoyl_2,HlyD,HlyD_3
CMS1_k127_4900702_13	857087.Metme_0213	2.753e-21	95.0	COG2026@1|root,COG2026@2|Bacteria,1NGC6@1224|Proteobacteria,1SI2E@1236|Gammaproteobacteria	1236|Gammaproteobacteria	DJ	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
CMS1_k127_4900702_10	472759.Nhal_0606	6.967e-34	134.0	COG1476@1|root,COG1476@2|Bacteria,1R0HS@1224|Proteobacteria,1T4HW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_4900702_7	1158756.AQXQ01000012_gene1227	6.069e-97	323.0	COG1943@1|root,COG1943@2|Bacteria,1RBFM@1224|Proteobacteria,1SPM8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
CMS1_k127_4900702_9	1177179.A11A3_02612	3.173e-48	176.0	COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,1RP1N@1236|Gammaproteobacteria,1XI0A@135619|Oceanospirillales	135619|Oceanospirillales	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
CMS1_k127_5036837_0	1249627.D779_3250	9.806e-175	556.0	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,1RPKC@1236|Gammaproteobacteria,1WX6G@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
CMS1_k127_5036837_2	1123261.AXDW01000002_gene1513	1.187e-112	381.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RM7S@1236|Gammaproteobacteria,1X3R2@135614|Xanthomonadales	135614|Xanthomonadales	M	membrane	-	-	-	-	-	-	-	-	-	-	-	-	OapA,Peptidase_M23
CMS1_k127_5036837_1	472759.Nhal_1102	1.097e-112	378.0	COG2377@1|root,COG2377@2|Bacteria,1MV4E@1224|Proteobacteria,1RNTZ@1236|Gammaproteobacteria,1WXXP@135613|Chromatiales	135613|Chromatiales	O	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
CMS1_k127_5036837_6	1030157.AFMP01000002_gene2155	2.22e-23	105.0	COG2940@1|root,COG2940@2|Bacteria,1Q9DE@1224|Proteobacteria,2VDKT@28211|Alphaproteobacteria,2K32C@204457|Sphingomonadales	204457|Sphingomonadales	S	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
CMS1_k127_5036837_4	1123401.JHYQ01000004_gene2318	1.788e-52	189.0	COG0316@1|root,COG0316@2|Bacteria,1RHCW@1224|Proteobacteria,1S675@1236|Gammaproteobacteria,460R0@72273|Thiotrichales	72273|Thiotrichales	C	Iron--sulfur cluster insertion protein erpA	erpA	-	-	ko:K15724	-	-	-	-	ko00000	-	-	-	Fe-S_biosyn
CMS1_k127_5036837_5	395493.BegalDRAFT_1306	3.744e-45	168.0	COG1664@1|root,COG1664@2|Bacteria,1PDPX@1224|Proteobacteria,1S9XY@1236|Gammaproteobacteria,461BH@72273|Thiotrichales	72273|Thiotrichales	M	Integral membrane protein CcmA involved in cell shape determination	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
CMS1_k127_5036837_7	472759.Nhal_3567	1.711e-21	103.0	2DA4I@1|root,32TUN@2|Bacteria,1N0WK@1224|Proteobacteria,1S6HI@1236|Gammaproteobacteria,1WZS1@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5036837_3	1485544.JQKP01000004_gene457	5.428e-77	262.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,2VJD7@28216|Betaproteobacteria,44V0R@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
CMS1_k127_5103613_15	879212.DespoDRAFT_02934	3.417e-42	158.0	COG3174@1|root,COG3174@2|Bacteria,1NDBI@1224|Proteobacteria,42QBM@68525|delta/epsilon subdivisions,2WNZE@28221|Deltaproteobacteria,2MNJM@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4010)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010,MgtC
CMS1_k127_5103613_12	1232410.KI421422_gene2082	1.451e-51	193.0	COG1711@1|root,COG1711@2|Bacteria,1RIA0@1224|Proteobacteria,42WF1@68525|delta/epsilon subdivisions,2WS1V@28221|Deltaproteobacteria,43V41@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3014)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3014
CMS1_k127_5103613_8	32057.KB217481_gene8582	2.179e-58	207.0	COG3812@1|root,COG3812@2|Bacteria,1G61H@1117|Cyanobacteria,1HN2I@1161|Nostocales	1117|Cyanobacteria	S	Domain of unknown function (DUF1993)	-	-	-	ko:K09983	-	-	-	-	ko00000	-	-	-	DUF1993
CMS1_k127_5103613_3	1005048.CFU_2572	8.669e-140	464.0	COG4642@1|root,COG4642@2|Bacteria,1P07C@1224|Proteobacteria,2WGN2@28216|Betaproteobacteria,4765J@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Peptidase C13 family	-	-	-	-	-	-	-	-	-	-	-	-	MORN,Peptidase_C13
CMS1_k127_5103613_0	330214.NIDE0058	1.687e-221	698.0	COG2211@1|root,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	BT1,MFS_1
CMS1_k127_5103613_10	1499967.BAYZ01000097_gene4355	9.199e-57	205.0	COG2426@1|root,COG2426@2|Bacteria	2|Bacteria	S	small multidrug export protein	-	-	-	-	-	-	-	-	-	-	-	-	Sm_multidrug_ex
CMS1_k127_5103613_2	472759.Nhal_1703	6.625e-153	488.0	COG1313@1|root,COG1313@2|Bacteria,1NZAK@1224|Proteobacteria	1224|Proteobacteria	C	radical SAM domain protein	-	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
CMS1_k127_5103613_16	1255043.TVNIR_1527	2.231e-30	120.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,1WZ2Z@135613|Chromatiales	135613|Chromatiales	K	PFAM Cold-shock protein, DNA-binding	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
CMS1_k127_5103613_13	1116472.MGMO_54c00070	4.099e-48	179.0	COG0558@1|root,COG0558@2|Bacteria,1N35Q@1224|Proteobacteria,1T0Q8@1236|Gammaproteobacteria,1XFBQ@135618|Methylococcales	135618|Methylococcales	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	-	-	-	-	-	-	-	-	-	-	CDP-OH_P_transf
CMS1_k127_5103613_6	153948.NAL212_2514	4.413e-94	315.0	COG3568@1|root,COG3568@2|Bacteria,1MVN7@1224|Proteobacteria,2VJYW@28216|Betaproteobacteria,372S8@32003|Nitrosomonadales	28216|Betaproteobacteria	L	PFAM Endonuclease exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CMS1_k127_5103613_1	472759.Nhal_3808	1.879e-209	656.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,1RQS1@1236|Gammaproteobacteria,1WYV6@135613|Chromatiales	135613|Chromatiales	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
CMS1_k127_5103613_9	1121921.KB898714_gene1842	3.439e-57	206.0	COG2755@1|root,COG2755@2|Bacteria,1RHDZ@1224|Proteobacteria,1S60V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	PFAM lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS1_k127_5103613_4	395963.Bind_2622	8.834e-100	338.0	COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,2TQNW@28211|Alphaproteobacteria,3NC6W@45404|Beijerinckiaceae	28211|Alphaproteobacteria	C	FMN-dependent dehydrogenase	lldD2	-	1.1.2.3,1.1.99.31	ko:K00101,ko:K15054	ko00620,ko00627,ko01100,ko01120,map00620,map00627,map01100,map01120	-	R00196,R04160,R07664	RC00044,RC00240	ko00000,ko00001,ko01000	-	-	-	FMN_dh
CMS1_k127_5103613_5	247633.GP2143_11964	4.648e-96	329.0	COG2199@1|root,COG2199@2|Bacteria,1R80Z@1224|Proteobacteria,1RZUV@1236|Gammaproteobacteria,1J6B5@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	COG2199 FOG GGDEF domain	yliF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	iSBO_1134.SBO_0726	GAPES2,GGDEF
CMS1_k127_5103613_14	156889.Mmc1_3142	2.731e-46	179.0	COG1716@1|root,COG2114@1|root,COG1716@2|Bacteria,COG2114@2|Bacteria,1NAJG@1224|Proteobacteria,2TSVT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Guanylate_cyc,SnoaL_3
CMS1_k127_5103613_7	261292.Nit79A3_1820	9.88e-75	253.0	COG1881@1|root,COG1881@2|Bacteria,1N0Y4@1224|Proteobacteria,2VR39@28216|Betaproteobacteria,37318@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Phosphatidylethanolamine-binding protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
CMS1_k127_5103613_11	1122201.AUAZ01000004_gene3335	1.439e-51	188.0	COG3108@1|root,COG3108@2|Bacteria,1MWW2@1224|Proteobacteria,1RS5K@1236|Gammaproteobacteria,46B76@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Bacterial protein of unknown function (DUF882)	ycbK	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_2
CMS1_k127_5134476_3	596151.DesfrDRAFT_3108	8.037e-72	249.0	COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,42MAX@68525|delta/epsilon subdivisions,2WJ5B@28221|Deltaproteobacteria,2M7XR@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	PFAM Glutamyl glutaminyl-tRNA synthetase, class Ic, catalytic	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	GatB_Yqey,tRNA-synt_1c,tRNA-synt_1c_C
CMS1_k127_5134476_1	472759.Nhal_3718	3.827e-105	356.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RND5@1236|Gammaproteobacteria,1WVWX@135613|Chromatiales	135613|Chromatiales	CH	TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6	-	-	-	ko:K18800	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04987,R08768	RC00046	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
CMS1_k127_5134476_2	713586.KB900536_gene2597	1.323e-96	329.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,1RMS3@1236|Gammaproteobacteria,1WW09@135613|Chromatiales	135613|Chromatiales	CH	Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6	-	-	-	ko:K03185	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04989,R08773	RC02670	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
CMS1_k127_5134476_0	105559.Nwat_0540	5.804e-196	621.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,1RN0W@1236|Gammaproteobacteria,1WWJH@135613|Chromatiales	135613|Chromatiales	E	peptidase M24B, X-Pro dipeptidase aminopeptidase	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
CMS1_k127_5134476_4	1168067.JAGP01000001_gene698	2.037e-21	104.0	COG3079@1|root,COG3079@2|Bacteria,1N7W0@1224|Proteobacteria,1SCPW@1236|Gammaproteobacteria,4619U@72273|Thiotrichales	72273|Thiotrichales	S	Belongs to the UPF0149 family	-	-	-	ko:K09895	-	-	-	-	ko00000	-	-	-	UPF0149
CMS1_k127_5134476_6	340.xcc-b100_0923	9.157e-12	67.0	2C0ET@1|root,33A9M@2|Bacteria,1NGE5@1224|Proteobacteria,1SGID@1236|Gammaproteobacteria,1X83G@135614|Xanthomonadales	135614|Xanthomonadales	S	TIGRFAM TIGR02449 family protein	VL23_04670	-	-	ko:K09892	-	-	-	-	ko00000,ko03036	-	-	-	ZapB
CMS1_k127_5134476_5	396588.Tgr7_2768	7.688e-18	88.0	COG3027@1|root,COG3027@2|Bacteria,1N6YN@1224|Proteobacteria,1SCBI@1236|Gammaproteobacteria,1WZF3@135613|Chromatiales	135613|Chromatiales	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	-	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
CMS1_k127_5231561_18	555778.Hneap_2189	8.057e-35	134.0	COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,1S3RW@1236|Gammaproteobacteria,1WVXA@135613|Chromatiales	135613|Chromatiales	K	Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins	-	-	-	ko:K13643	-	-	-	-	ko00000,ko03000	-	-	-	Rrf2
CMS1_k127_5231561_8	1123401.JHYQ01000027_gene3134	1.068e-89	302.0	COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,1RNCA@1236|Gammaproteobacteria,4608T@72273|Thiotrichales	72273|Thiotrichales	E	TIGRFAM Serine O-acetyltransferase	-	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
CMS1_k127_5231561_0	396588.Tgr7_2144	0.0	1309.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,1RNEB@1236|Gammaproteobacteria,1WWJI@135613|Chromatiales	135613|Chromatiales	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
CMS1_k127_5231561_20	472759.Nhal_3009	3.846e-29	121.0	COG2927@1|root,COG2927@2|Bacteria,1MZ3V@1224|Proteobacteria,1S94K@1236|Gammaproteobacteria,1WYQ1@135613|Chromatiales	135613|Chromatiales	L	DNA polymerase III, chi subunit	-	-	2.7.7.7	ko:K02339	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_chi
CMS1_k127_5231561_3	396588.Tgr7_2140	5.476e-213	671.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,1RNM1@1236|Gammaproteobacteria,1WW8I@135613|Chromatiales	135613|Chromatiales	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
CMS1_k127_5231561_15	1286106.MPL1_04947	5.098e-55	207.0	COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,1RMN5@1236|Gammaproteobacteria,460RT@72273|Thiotrichales	72273|Thiotrichales	S	Permease YjgP YjgQ	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
CMS1_k127_5231561_10	472759.Nhal_3015	1.573e-77	272.0	COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,1RM8H@1236|Gammaproteobacteria,1WWXY@135613|Chromatiales	135613|Chromatiales	S	Permease YjgP YjgQ	-	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
CMS1_k127_5231561_19	472759.Nhal_3016	9.656e-34	134.0	COG1714@1|root,COG1714@2|Bacteria,1N4N8@1224|Proteobacteria,1S9C5@1236|Gammaproteobacteria,1WYQZ@135613|Chromatiales	135613|Chromatiales	S	pfam rdd	-	-	-	-	-	-	-	-	-	-	-	-	RDD
CMS1_k127_5231561_4	765912.Thimo_3510	2.599e-135	447.0	COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,1RMBG@1236|Gammaproteobacteria,1WWHC@135613|Chromatiales	135613|Chromatiales	J	Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control	pcnB	-	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C
CMS1_k127_5231561_17	472759.Nhal_1071	7.944e-45	167.0	COG0801@1|root,COG0801@2|Bacteria,1MZH8@1224|Proteobacteria,1S63J@1236|Gammaproteobacteria,1WYWG@135613|Chromatiales	135613|Chromatiales	H	PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK	-	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
CMS1_k127_5231561_7	870187.Thini_4164	9.541e-92	309.0	COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,1RM8D@1236|Gammaproteobacteria,4609A@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
CMS1_k127_5231561_9	314278.NB231_15428	2.081e-80	279.0	COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,1RMEG@1236|Gammaproteobacteria,1WW2E@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
CMS1_k127_5231561_14	1026882.MAMP_01829	7.958e-56	198.0	COG0853@1|root,COG0853@2|Bacteria,1RI1B@1224|Proteobacteria,1S66E@1236|Gammaproteobacteria,460PH@72273|Thiotrichales	72273|Thiotrichales	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
CMS1_k127_5231561_21	713586.KB900536_gene1877	1.643e-22	100.0	COG1734@1|root,COG1734@2|Bacteria,1N8K6@1224|Proteobacteria,1SCNZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	DnaK suppressor protein	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
CMS1_k127_5231561_22	161156.JQKW01000012_gene2	3.176e-22	102.0	COG0517@1|root,COG0517@2|Bacteria,2GHNE@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	CBS
CMS1_k127_5231561_12	396588.Tgr7_0212	1.545e-64	229.0	COG0664@1|root,COG0664@2|Bacteria,1MVGE@1224|Proteobacteria,1RPTB@1236|Gammaproteobacteria,1WWQ7@135613|Chromatiales	135613|Chromatiales	K	Transcriptional regulator	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CMS1_k127_5231561_16	1117958.PE143B_0108080	3.787e-45	173.0	COG2836@1|root,COG2836@2|Bacteria,1RIGJ@1224|Proteobacteria,1S5TB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2
CMS1_k127_5231561_23	1121943.KB899989_gene3364	9.743e-10	61.0	COG3197@1|root,COG3197@2|Bacteria,1NG90@1224|Proteobacteria,1SGQG@1236|Gammaproteobacteria,1XMBA@135619|Oceanospirillales	135619|Oceanospirillales	P	Cytochrome oxidase maturation protein	-	-	-	-	-	-	-	-	-	-	-	-	FixS
CMS1_k127_5231561_2	395493.BegalDRAFT_2459	3.632e-234	750.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,45ZPW@72273|Thiotrichales	72273|Thiotrichales	P	heavy metal translocating P-type ATPase	-	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
CMS1_k127_5231561_25	2340.JV46_28230	9.83e-07	56.0	28YWM@1|root,2ZKPR@2|Bacteria,1PBMF@1224|Proteobacteria,1SWFV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5231561_13	472759.Nhal_1109	5.572e-58	213.0	COG3064@1|root,COG3064@2|Bacteria,1RKXA@1224|Proteobacteria,1SPCG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5231561_1	713586.KB900536_gene1496	1.16e-258	803.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,1RM7I@1236|Gammaproteobacteria,1WXK9@135613|Chromatiales	135613|Chromatiales	C	Belongs to the heme-copper respiratory oxidase family	-	-	1.9.3.1	ko:K00404	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1
CMS1_k127_5231561_6	760117.JN27_04155	1.132e-97	325.0	COG2993@1|root,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,2VIJ2@28216|Betaproteobacteria,472VR@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Cytochrome C oxidase, mono-heme subunit/FixO	ccoO	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixO
CMS1_k127_5231561_24	1123519.PSJM300_12005	5.819e-07	55.0	COG4736@1|root,COG4736@2|Bacteria,1NGAN@1224|Proteobacteria,1SGJ2@1236|Gammaproteobacteria,1Z3E2@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	O	COG4736 Cbb3-type cytochrome oxidase, subunit 3	ccoQ	-	-	ko:K00407	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	FixQ
CMS1_k127_5231561_5	279714.FuraDRAFT_1094	1.356e-103	344.0	COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,2VHGS@28216|Betaproteobacteria,2KQ3Y@206351|Neisseriales	206351|Neisseriales	C	Cytochrome c oxidase, subunit	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N,OmpA
CMS1_k127_5231561_26	62928.azo1348	4.571e-05	52.0	2EFX9@1|root,32YGP@2|Bacteria,1N7MN@1224|Proteobacteria,2VW9F@28216|Betaproteobacteria,2KXDY@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5231561_11	395493.BegalDRAFT_2182	3.127e-75	256.0	COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,1RMDI@1236|Gammaproteobacteria,4601I@72273|Thiotrichales	72273|Thiotrichales	C	TIGRFAM cytochrome c oxidase accessory protein FixG	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
CMS1_k127_5255229_7	314231.FP2506_02475	2.465e-06	49.0	COG1073@1|root,COG1073@2|Bacteria,1MX88@1224|Proteobacteria,2TSRE@28211|Alphaproteobacteria,2PJMW@255475|Aurantimonadaceae	28211|Alphaproteobacteria	S	Alpha/beta hydrolase family	MA20_24420	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_6,Hydrolase_4
CMS1_k127_5255229_4	1396.DJ87_389	4.166e-49	178.0	2DZGK@1|root,32VA1@2|Bacteria,1VWEM@1239|Firmicutes,4HWQM@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5255229_8	1120963.KB894491_gene1107	9.839e-06	48.0	2DE24@1|root,2ZK69@2|Bacteria,1P9N5@1224|Proteobacteria,1SU0Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5255229_2	1323663.AROI01000009_gene3530	2.738e-115	386.0	COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,1RNZE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006464,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0042802,GO:0043021,GO:0043022,GO:0043170,GO:0043335,GO:0043412,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0050896,GO:0051083,GO:0061077,GO:0071704,GO:0140096,GO:1901564	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
CMS1_k127_5255229_3	1158760.AQXP01000046_gene274	1.877e-101	334.0	COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,1RNR6@1236|Gammaproteobacteria,1WW24@135613|Chromatiales	135613|Chromatiales	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
CMS1_k127_5255229_1	472759.Nhal_3107	2.046e-223	698.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,1RN9N@1236|Gammaproteobacteria,1WX82@135613|Chromatiales	135613|Chromatiales	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
CMS1_k127_5255229_0	395493.BegalDRAFT_2469	0.0	1179.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,1RPCB@1236|Gammaproteobacteria,4605Q@72273|Thiotrichales	72273|Thiotrichales	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
CMS1_k127_5255229_5	935567.JAES01000015_gene2785	2.574e-34	134.0	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,1S8VH@1236|Gammaproteobacteria,1X7FC@135614|Xanthomonadales	135614|Xanthomonadales	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hupB	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
CMS1_k127_5255229_6	106648.BBLJ01000011_gene1070	1.45e-07	54.0	2DR59@1|root,33A7S@2|Bacteria,1NMH2@1224|Proteobacteria,1SIVW@1236|Gammaproteobacteria,3NS87@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_532195_7	105559.Nwat_0271	1.954e-11	67.0	COG2020@1|root,COG2020@2|Bacteria,1RJNV@1224|Proteobacteria,1SGB2@1236|Gammaproteobacteria,1X1KG@135613|Chromatiales	135613|Chromatiales	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
CMS1_k127_532195_6	1198232.CYCME_1670	7.707e-17	91.0	COG1266@1|root,COG1266@2|Bacteria,1R6Z1@1224|Proteobacteria,1RRIS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PFAM Abortive infection protein	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
CMS1_k127_532195_3	1500893.JQNB01000001_gene971	2.049e-77	269.0	COG0463@1|root,COG0463@2|Bacteria,1MW2G@1224|Proteobacteria,1S22P@1236|Gammaproteobacteria,1X3J4@135614|Xanthomonadales	135614|Xanthomonadales	M	Dolichol-phosphate mannosyltransferase	dpm1	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
CMS1_k127_532195_4	1268635.Loa_02113	1.452e-32	131.0	COG3952@1|root,COG3952@2|Bacteria,1MZ60@1224|Proteobacteria,1S8XM@1236|Gammaproteobacteria,1JF2T@118969|Legionellales	118969|Legionellales	S	Lipid A Biosynthesis N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	LAB_N
CMS1_k127_532195_2	314278.NB231_15368	1.843e-85	303.0	COG1807@1|root,COG1807@2|Bacteria,1NMIZ@1224|Proteobacteria,1S48Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
CMS1_k127_532195_5	1499967.BAYZ01000195_gene3112	4.936e-23	113.0	COG1807@1|root,COG1807@2|Bacteria,2NR43@2323|unclassified Bacteria	2|Bacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2,PMT_2
CMS1_k127_532195_1	1192034.CAP_1677	2.652e-195	617.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,42N8U@68525|delta/epsilon subdivisions,2WJAN@28221|Deltaproteobacteria,2YYIW@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
CMS1_k127_532195_0	580332.Slit_0060	2.08e-322	1005.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,2VHYQ@28216|Betaproteobacteria,44V3A@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Vitamin B12 dependent methionine synthase activation region	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
CMS1_k127_5336101_1	765912.Thimo_1199	1.322e-210	661.0	COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,1RN4K@1236|Gammaproteobacteria,1WVYF@135613|Chromatiales	135613|Chromatiales	C	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
CMS1_k127_5336101_9	1384054.N790_12480	9.528e-48	178.0	COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,1S41D@1236|Gammaproteobacteria,1X6FV@135614|Xanthomonadales	135614|Xanthomonadales	D	Maf-like protein	-	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
CMS1_k127_5336101_10	631362.Thi970DRAFT_03040	5.325e-47	175.0	COG1576@1|root,COG1576@2|Bacteria,1R9Z2@1224|Proteobacteria,1S1ZY@1236|Gammaproteobacteria,1WY5P@135613|Chromatiales	135613|Chromatiales	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
CMS1_k127_5336101_11	1234364.AMSF01000056_gene1115	5.441e-33	135.0	COG0799@1|root,COG0799@2|Bacteria,1MZEF@1224|Proteobacteria,1S8W3@1236|Gammaproteobacteria,1X6H0@135614|Xanthomonadales	135614|Xanthomonadales	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
CMS1_k127_5336101_8	686340.Metal_2666	3.454e-55	201.0	COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,1RP00@1236|Gammaproteobacteria,1XF1C@135618|Methylococcales	135618|Methylococcales	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
CMS1_k127_5336101_2	1163617.SCD_n00056	2.565e-177	565.0	COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,2VJ5M@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
CMS1_k127_5336101_6	519989.ECTPHS_03026	3.08e-79	276.0	COG1466@1|root,COG1466@2|Bacteria,1MWYT@1224|Proteobacteria,1RQRE@1236|Gammaproteobacteria,1WWRB@135613|Chromatiales	135613|Chromatiales	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delt_C,DNA_pol3_delta
CMS1_k127_5336101_13	748247.AZKH_1273	1.943e-12	74.0	COG2980@1|root,COG2980@2|Bacteria,1N13K@1224|Proteobacteria,2VU54@28216|Betaproteobacteria,2KWYS@206389|Rhodocyclales	206389|Rhodocyclales	M	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane	lptE	-	-	ko:K03643	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptE
CMS1_k127_5336101_0	1123487.KB892867_gene1012	0.0	1260.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,2VH2J@28216|Betaproteobacteria,2KV8K@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
CMS1_k127_5336101_12	767434.Fraau_2511	2.672e-18	87.0	COG1555@1|root,COG1555@2|Bacteria,1N6Q3@1224|Proteobacteria,1SC7U@1236|Gammaproteobacteria,1X84H@135614|Xanthomonadales	135614|Xanthomonadales	L	competence protein ComEA	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3
CMS1_k127_5336101_7	754477.Q7C_1745	5.541e-75	270.0	COG3746@1|root,COG3746@2|Bacteria,1N5TT@1224|Proteobacteria,1S11Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Phosphate-specific outer membrane porin OprP Pyrophosphate-specific outer membrane porin OprO	-	-	-	ko:K07221	-	-	-	-	ko00000,ko02000	1.B.5.1	-	-	Porin_O_P
CMS1_k127_5336101_5	472759.Nhal_2287	1.185e-88	298.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,1RN41@1236|Gammaproteobacteria,1WVZG@135613|Chromatiales	135613|Chromatiales	T	phosphate regulon transcriptional regulatory protein PhoB	-	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_5336101_4	1215092.PA6_032_00780	5.218e-113	379.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,1RN0F@1236|Gammaproteobacteria,1YFDI@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	T	Domain of unknown function (DUF3329)	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF3329,HATPase_c,HisKA,PAS,PAS_8
CMS1_k127_5336101_3	472759.Nhal_2289	1.296e-142	459.0	COG0226@1|root,COG0226@2|Bacteria,1MVXP@1224|Proteobacteria,1RQDH@1236|Gammaproteobacteria,1WXSW@135613|Chromatiales	135613|Chromatiales	P	TIGRFAM phosphate binding protein	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
CMS1_k127_5517755_2	395493.BegalDRAFT_1677	3.368e-271	842.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,1RMH3@1236|Gammaproteobacteria,45ZV1@72273|Thiotrichales	72273|Thiotrichales	O	ATP-dependent Clp protease ATP-binding subunit ClpA	-	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
CMS1_k127_5517755_11	395493.BegalDRAFT_1985	3.141e-142	464.0	COG0548@1|root,COG1246@1|root,COG0548@2|Bacteria,COG1246@2|Bacteria,1MUUP@1224|Proteobacteria,1RMV5@1236|Gammaproteobacteria,45ZXD@72273|Thiotrichales	72273|Thiotrichales	E	Belongs to the acetyltransferase family. ArgA subfamily	argA	-	2.3.1.1	ko:K14682	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,Acetyltransf_1,Acetyltransf_7
CMS1_k127_5517755_10	396588.Tgr7_0573	1.463e-144	467.0	COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,1RNDG@1236|Gammaproteobacteria,1WX3F@135613|Chromatiales	135613|Chromatiales	E	Belongs to the peptidase M20A family. ArgE subfamily	-	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
CMS1_k127_5517755_1	344747.PM8797T_12503	7.67e-286	885.0	COG0129@1|root,COG0129@2|Bacteria,2IWXV@203682|Planctomycetes	203682|Planctomycetes	H	Belongs to the IlvD Edd family	ilvD	GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
CMS1_k127_5517755_30	697282.Mettu_3957	2.478e-55	201.0	COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,1S8R3@1236|Gammaproteobacteria,1XF3W@135618|Methylococcales	135618|Methylococcales	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124,SLT
CMS1_k127_5517755_40	1286631.X805_23570	2.231e-16	85.0	2E53F@1|root,32ZWJ@2|Bacteria,1N6KB@1224|Proteobacteria,2VRMT@28216|Betaproteobacteria,1KM01@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5517755_42	998674.ATTE01000001_gene3302	3.137e-11	71.0	2E53F@1|root,32ZWJ@2|Bacteria,1N6KB@1224|Proteobacteria,1SFTY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5517755_26	395495.Lcho_1798	2.18e-65	229.0	28NA5@1|root,2ZBDZ@2|Bacteria,1MXY5@1224|Proteobacteria,2VMFN@28216|Betaproteobacteria,1KKFX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5517755_37	998674.ATTE01000001_gene3300	7.057e-20	99.0	COG0811@1|root,COG0811@2|Bacteria,1PPAP@1224|Proteobacteria,1SEK5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	MotA/TolQ/ExbB proton channel family	-	-	-	-	-	-	-	-	-	-	-	-	MotA_ExbB
CMS1_k127_5517755_31	1049564.TevJSym_ad00730	2.335e-52	189.0	COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,1S68A@1236|Gammaproteobacteria,1J67X@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)	pgpA	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008962,GO:0009058,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0030258,GO:0031224,GO:0031226,GO:0032026,GO:0042221,GO:0042577,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0046839,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901576	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	iECSP_1301.ECSP_0485,iECUMN_1333.ECUMN_0456,iECs_1301.ECs0471,iG2583_1286.G2583_0529,iPC815.YPO3179,iZ_1308.Z0520	PgpA
CMS1_k127_5517755_41	1177154.Y5S_00479	6.684e-12	77.0	294RE@1|root,2ZS4P@2|Bacteria,1P9TN@1224|Proteobacteria,1SV2K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5517755_29	794903.OPIT5_19005	3.094e-59	216.0	COG2084@1|root,COG2084@2|Bacteria,46V72@74201|Verrucomicrobia,3K7A1@414999|Opitutae	414999|Opitutae	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_11,NAD_binding_2
CMS1_k127_5517755_32	323848.Nmul_A1031	4.906e-42	158.0	COG2363@1|root,COG2363@2|Bacteria,1MZX3@1224|Proteobacteria,2VU8X@28216|Betaproteobacteria,373CU@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF423)	ygdD	-	-	-	-	-	-	-	-	-	-	-	DUF423
CMS1_k127_5517755_25	1047013.AQSP01000130_gene1856	6.618e-74	256.0	COG3836@1|root,COG3836@2|Bacteria,2NPSY@2323|unclassified Bacteria	2|Bacteria	G	HpcH/HpaI aldolase/citrate lyase family	MA20_09190	-	2.7.7.38,4.1.2.20,4.1.2.52	ko:K00979,ko:K01630,ko:K02510	ko00053,ko00350,ko00540,ko01100,ko01120,map00053,map00350,map00540,map01100,map01120	M00063	R01645,R01647,R02754,R03277,R03351,R11396	RC00152,RC00307,RC00435,RC00572,RC00574,RC00910,RC03057	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	HpcH_HpaI
CMS1_k127_5517755_17	1469245.JFBG01000027_gene1488	8.008e-113	380.0	COG2027@1|root,COG2027@2|Bacteria,1MW40@1224|Proteobacteria,1RP8V@1236|Gammaproteobacteria,1WWVE@135613|Chromatiales	135613|Chromatiales	M	PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
CMS1_k127_5517755_24	1283300.ATXB01000001_gene428	1.991e-76	263.0	COG1814@1|root,COG1814@2|Bacteria,1MUZE@1224|Proteobacteria,1S2G7@1236|Gammaproteobacteria,1XFWX@135618|Methylococcales	135618|Methylococcales	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
CMS1_k127_5517755_38	318161.Sden_1471	1.333e-19	93.0	293WK@1|root,2ZRBR@2|Bacteria,1PBHQ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5517755_19	391735.Veis_2331	8.993e-86	288.0	COG2755@1|root,COG2755@2|Bacteria,1RDVJ@1224|Proteobacteria,2VHK1@28216|Betaproteobacteria	28216|Betaproteobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
CMS1_k127_5517755_45	1230343.CANP01000031_gene2345	0.0002248	52.0	COG0790@1|root,COG0790@2|Bacteria,1QC22@1224|Proteobacteria,1T7PT@1236|Gammaproteobacteria,1JFNG@118969|Legionellales	118969|Legionellales	S	Sel1-like repeats.	-	-	-	-	-	-	-	-	-	-	-	-	Sel1
CMS1_k127_5517755_3	155515.JP36_05905	4.009e-261	820.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,1RMJB@1236|Gammaproteobacteria,1Y7I2@135625|Pasteurellales	135625|Pasteurellales	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
CMS1_k127_5517755_13	395493.BegalDRAFT_2944	4.775e-138	455.0	COG0260@1|root,COG0260@2|Bacteria,1MXP6@1224|Proteobacteria,1RYKJ@1236|Gammaproteobacteria,461SM@72273|Thiotrichales	72273|Thiotrichales	E	Cytosol aminopeptidase family, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M17
CMS1_k127_5517755_0	765912.Thimo_1087	0.0	1373.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,1RN6K@1236|Gammaproteobacteria,1WWE0@135613|Chromatiales	135613|Chromatiales	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
CMS1_k127_5517755_8	396588.Tgr7_2455	3.22e-148	481.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,1RNPT@1236|Gammaproteobacteria,1WW8D@135613|Chromatiales	135613|Chromatiales	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
CMS1_k127_5517755_6	1163617.SCD_n00853	3.576e-200	632.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2VI6G@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Dehydrogenase	lpdA	GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim
CMS1_k127_5517755_34	748247.AZKH_0395	5.656e-36	147.0	COG2834@1|root,COG2834@2|Bacteria,1NEDP@1224|Proteobacteria	1224|Proteobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5517755_43	338969.Rfer_4082	1.855e-09	64.0	COG3005@1|root,COG3005@2|Bacteria,1R4UP@1224|Proteobacteria,2VM47@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Decaheme c-type cytochrome, DmsE family	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
CMS1_k127_5517755_28	1283300.ATXB01000001_gene1985	6.399e-60	216.0	COG0596@1|root,COG0596@2|Bacteria,1R9X7@1224|Proteobacteria,1S2CW@1236|Gammaproteobacteria,1XEB6@135618|Methylococcales	135618|Methylococcales	S	Thioesterase domain	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
CMS1_k127_5517755_5	519989.ECTPHS_11447	1.077e-212	666.0	COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,1RMEC@1236|Gammaproteobacteria,1WXPT@135613|Chromatiales	135613|Chromatiales	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
CMS1_k127_5517755_27	580332.Slit_0397	4.845e-64	223.0	COG5496@1|root,COG5496@2|Bacteria,1RKFT@1224|Proteobacteria,2VV65@28216|Betaproteobacteria,44WEX@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Thioesterase	-	-	3.1.2.29	ko:K18700	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
CMS1_k127_5517755_21	207954.MED92_02151	4.543e-83	291.0	COG0025@1|root,COG0025@2|Bacteria,1MW5T@1224|Proteobacteria,1RPH6@1236|Gammaproteobacteria,1XKFV@135619|Oceanospirillales	135619|Oceanospirillales	P	Sodium/hydrogen exchanger family	-	-	-	ko:K03316	-	-	-	-	ko00000	2.A.36	-	-	Na_H_Exchanger
CMS1_k127_5517755_4	722419.PH505_aq00240	1.767e-222	700.0	COG0069@1|root,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,1RP1C@1236|Gammaproteobacteria,2PZNH@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	E	Belongs to the glutamate synthase family	-	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase
CMS1_k127_5517755_23	472759.Nhal_2720	1.443e-77	270.0	COG3219@1|root,COG3219@2|Bacteria,1R8C9@1224|Proteobacteria,1S23S@1236|Gammaproteobacteria,1WXZ1@135613|Chromatiales	135613|Chromatiales	S	Putative DNA-binding domain	-	-	-	ko:K09929	-	-	-	-	ko00000	-	-	-	DUF2063
CMS1_k127_5517755_16	713586.KB900536_gene2708	1.909e-116	382.0	COG3220@1|root,COG3220@2|Bacteria,1MURE@1224|Proteobacteria,1RQ9H@1236|Gammaproteobacteria,1WWJ1@135613|Chromatiales	135613|Chromatiales	S	Belongs to the UPF0276 family	-	-	-	ko:K09930	-	-	-	-	ko00000	-	-	-	DUF692
CMS1_k127_5517755_46	686340.Metal_0167	0.0008554	47.0	COG3767@1|root,COG3767@2|Bacteria,1QJQT@1224|Proteobacteria,1THS2@1236|Gammaproteobacteria,1XFHU@135618|Methylococcales	135618|Methylococcales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5517755_44	518766.Rmar_2225	1.583e-08	59.0	COG5660@1|root,COG5660@2|Bacteria,4PF9I@976|Bacteroidetes,1FKBP@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
CMS1_k127_5517755_35	314230.DSM3645_06149	1.001e-31	133.0	COG1595@1|root,COG1595@2|Bacteria,2J0GI@203682|Planctomycetes	203682|Planctomycetes	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_5517755_22	472759.Nhal_2720	5.998e-83	285.0	COG3219@1|root,COG3219@2|Bacteria,1R8C9@1224|Proteobacteria,1S23S@1236|Gammaproteobacteria,1WXZ1@135613|Chromatiales	135613|Chromatiales	S	Putative DNA-binding domain	-	-	-	ko:K09929	-	-	-	-	ko00000	-	-	-	DUF2063
CMS1_k127_5517755_14	768671.ThimaDRAFT_4545	2.469e-126	409.0	COG3220@1|root,COG3220@2|Bacteria,1MURE@1224|Proteobacteria,1RQ9H@1236|Gammaproteobacteria,1WWJ1@135613|Chromatiales	135613|Chromatiales	S	Belongs to the UPF0276 family	-	-	-	ko:K09930	-	-	-	-	ko00000	-	-	-	DUF692
CMS1_k127_5517755_39	523791.Kkor_0987	1.707e-16	84.0	COG3767@1|root,COG3767@2|Bacteria,1N9HK@1224|Proteobacteria,1SD4Q@1236|Gammaproteobacteria,1XKZ5@135619|Oceanospirillales	135619|Oceanospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5517755_7	1335757.SPICUR_06280	5.177e-187	599.0	COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,1RMJN@1236|Gammaproteobacteria,1WVXY@135613|Chromatiales	135613|Chromatiales	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
CMS1_k127_5517755_20	234267.Acid_3094	1.134e-83	302.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,3Y59I@57723|Acidobacteria	57723|Acidobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5517755_9	290397.Adeh_2253	3.012e-146	486.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,43BKG@68525|delta/epsilon subdivisions,2X6YU@28221|Deltaproteobacteria,2YYW6@29|Myxococcales	28221|Deltaproteobacteria	K	ATPase associated with various cellular activities, AAA_5	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,PAS_9,Sigma54_activat
CMS1_k127_5517755_15	297246.lpp0726	3.046e-125	412.0	COG1752@1|root,COG1752@2|Bacteria,1MVHW@1224|Proteobacteria,1SX77@1236|Gammaproteobacteria,1JD72@118969|Legionellales	118969|Legionellales	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
CMS1_k127_5517755_12	402881.Plav_0419	3.421e-141	464.0	COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,2TQT2@28211|Alphaproteobacteria,1JPY5@119043|Rhodobiaceae	28211|Alphaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	ndh	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,cNMP_binding
CMS1_k127_5517755_18	1528098.NOVO_06325	1.532e-111	370.0	COG4689@1|root,COG4689@2|Bacteria,1N4IP@1224|Proteobacteria,2TTZX@28211|Alphaproteobacteria,47G14@766|Rickettsiales	766|Rickettsiales	Q	Acetoacetate decarboxylase (ADC)	-	-	4.1.1.4	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	M00088	R01366	RC00040	ko00000,ko00001,ko00002,ko01000	-	-	-	ADC
CMS1_k127_5517755_36	1305735.JAFT01000005_gene2385	1.274e-21	94.0	COG1028@1|root,COG1028@2|Bacteria,1MU5Y@1224|Proteobacteria,2TRNQ@28211|Alphaproteobacteria,2PD2Q@252301|Oceanicola	28211|Alphaproteobacteria	IQ	KR domain	-	-	1.1.1.30	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	M00088	R01361	RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short,adh_short_C2
CMS1_k127_5519854_26	56110.Oscil6304_2660	1.481e-76	270.0	COG0438@1|root,COG0438@2|Bacteria,1G1VE@1117|Cyanobacteria,1H6WJ@1150|Oscillatoriales	1117|Cyanobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1,Methyltransf_11
CMS1_k127_5519854_22	102125.Xen7305DRAFT_00046450	4.188e-91	309.0	COG0451@1|root,COG0451@2|Bacteria,1GDI5@1117|Cyanobacteria	1117|Cyanobacteria	M	Male sterility protein	-	-	5.1.3.10	ko:K12454	ko00520,map00520	-	R04266	RC00528	ko00000,ko00001,ko01000	-	-	-	-
CMS1_k127_5519854_46	755178.Cyan10605_0302	2.785e-20	104.0	COG0438@1|root,COG0438@2|Bacteria,1G4YC@1117|Cyanobacteria	1117|Cyanobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4
CMS1_k127_5519854_5	1541065.JRFE01000001_gene2576	1.333e-201	632.0	COG0451@1|root,COG0451@2|Bacteria,1G0TM@1117|Cyanobacteria,3VIMA@52604|Pleurocapsales	1117|Cyanobacteria	GM	PFAM NAD dependent epimerase dehydratase family	sqdB	-	3.13.1.1	ko:K06118	ko00520,ko00561,map00520,map00561	-	R05775	RC01469	ko00000,ko00001,ko01000	-	-	-	Epimerase
CMS1_k127_5519854_43	1185876.BN8_06531	4.175e-34	143.0	COG1216@1|root,COG1216@2|Bacteria,4NIKM@976|Bacteroidetes,47M8F@768503|Cytophagia	976|Bacteroidetes	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
CMS1_k127_5519854_27	472759.Nhal_0381	1.379e-71	253.0	COG0438@1|root,COG0438@2|Bacteria,1RDVF@1224|Proteobacteria,1S4Y9@1236|Gammaproteobacteria,1X015@135613|Chromatiales	135613|Chromatiales	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
CMS1_k127_5519854_16	472759.Nhal_0594	2.359e-98	329.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,1RNME@1236|Gammaproteobacteria,1WWE2@135613|Chromatiales	135613|Chromatiales	G	Inositol monophosphatase	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
CMS1_k127_5519854_29	1121921.KB898708_gene1324	1.092e-64	230.0	COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,1RPD3@1236|Gammaproteobacteria,2PMN9@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	J	SpoU rRNA Methylase family	trmJ	-	2.1.1.200	ko:K02533,ko:K15396	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
CMS1_k127_5519854_13	572477.Alvin_1636	1.529e-130	428.0	COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,1RNZZ@1236|Gammaproteobacteria,1WWGF@135613|Chromatiales	135613|Chromatiales	F	PFAM AIR synthase related protein	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
CMS1_k127_5519854_41	1049564.TevJSym_af00840	1.155e-39	161.0	COG3249@1|root,COG3249@2|Bacteria,1N0PD@1224|Proteobacteria,1S9C4@1236|Gammaproteobacteria,1J69V@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	VV2512	-	-	ko:K09938	-	-	-	-	ko00000	-	-	-	DUF2066
CMS1_k127_5519854_32	440512.C211_06987	6.058e-54	198.0	COG0593@1|root,COG0593@2|Bacteria,1MVW6@1224|Proteobacteria,1RPJP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA	hda	GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008156,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030174,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:2000104,GO:2000112,GO:2000113	-	ko:K10763	-	-	-	-	ko00000,ko03032	-	-	-	Bac_DnaA
CMS1_k127_5519854_25	1249627.D779_2182	5.405e-84	282.0	COG0655@1|root,COG0655@2|Bacteria,1MW7N@1224|Proteobacteria,1S23B@1236|Gammaproteobacteria,1WW1Q@135613|Chromatiales	135613|Chromatiales	S	Belongs to the WrbA family	-	-	1.6.5.2	ko:K03809	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	FMN_red
CMS1_k127_5519854_39	105559.Nwat_0187	4.44e-40	151.0	COG1393@1|root,COG1393@2|Bacteria,1MZ4Z@1224|Proteobacteria,1S8XH@1236|Gammaproteobacteria,1X13D@135613|Chromatiales	135613|Chromatiales	P	Arsenate reductase and related	-	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC
CMS1_k127_5519854_30	1049564.TevJSym_af00790	1.516e-63	228.0	COG1295@1|root,COG1295@2|Bacteria,1QICW@1224|Proteobacteria,1RMKI@1236|Gammaproteobacteria,1J640@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Virulence factor BrkB	rbn	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
CMS1_k127_5519854_45	1232683.ADIMK_3741	3.748e-23	101.0	COG1254@1|root,COG1254@2|Bacteria,1N6NU@1224|Proteobacteria,1SCPF@1236|Gammaproteobacteria,468VX@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	acylphosphatase activity	acyP	GO:0003674,GO:0003824,GO:0003998,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016787,GO:0016817,GO:0016818,GO:0050896	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	iSBO_1134.SBO_2263,iSF_1195.SF0969,iSFxv_1172.SFxv_1053,iS_1188.S1036	Acylphosphatase
CMS1_k127_5519854_1	395493.BegalDRAFT_0391	2.272e-265	827.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,1RN5R@1236|Gammaproteobacteria,46011@72273|Thiotrichales	72273|Thiotrichales	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
CMS1_k127_5519854_0	395493.BegalDRAFT_2551	1.206e-299	926.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RMQQ@1236|Gammaproteobacteria,45ZVD@72273|Thiotrichales	72273|Thiotrichales	E	TIGRFAM Acetolactate synthase, large subunit, biosynthetic	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
CMS1_k127_5519854_28	2340.JV46_05740	3.936e-68	235.0	COG0440@1|root,COG0440@2|Bacteria,1RAGN@1224|Proteobacteria,1S20I@1236|Gammaproteobacteria,1J53Y@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	COG0440 Acetolactate synthase, small (regulatory) subunit	ilvH	GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_1906,iECNA114_1301.ECNA114_0072,iEcSMS35_1347.EcSMS35_0084,iG2583_1286.G2583_0082,iSFxv_1172.SFxv_0077,iUTI89_1310.UTI89_C0086	ACT,ACT_5,ALS_ss_C
CMS1_k127_5519854_6	187272.Mlg_0544	1.932e-172	546.0	COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,1RNA8@1236|Gammaproteobacteria,1WWXU@135613|Chromatiales	135613|Chromatiales	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
CMS1_k127_5519854_18	472759.Nhal_0658	2.751e-97	326.0	COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,1RPBB@1236|Gammaproteobacteria,1WWDZ@135613|Chromatiales	135613|Chromatiales	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
CMS1_k127_5519854_2	768671.ThimaDRAFT_0998	5.812e-262	814.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,1RMWE@1236|Gammaproteobacteria,1WWU2@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
CMS1_k127_5519854_23	105559.Nwat_0619	4.406e-87	294.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,1S2U7@1236|Gammaproteobacteria,1WWN0@135613|Chromatiales	135613|Chromatiales	L	TIGRFAM Phage SPO1 DNA polymerase-related protein	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
CMS1_k127_5519854_35	396588.Tgr7_2151	1.556e-51	186.0	COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,1S9G0@1236|Gammaproteobacteria,1WYDP@135613|Chromatiales	135613|Chromatiales	K	Ribosomal-protein-alanine acetyltransferase	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
CMS1_k127_5519854_9	1283300.ATXB01000001_gene1644	1.025e-145	467.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,1RN6J@1236|Gammaproteobacteria,1XE1W@135618|Methylococcales	135618|Methylococcales	E	Belongs to the cysteine synthase cystathionine beta- synthase family	-	-	-	-	-	-	-	-	-	-	-	-	PALP
CMS1_k127_5519854_15	323261.Noc_0800	3.594e-110	361.0	COG3298@1|root,COG3298@2|Bacteria,1MVZJ@1224|Proteobacteria,1S4HU@1236|Gammaproteobacteria,1X0C4@135613|Chromatiales	135613|Chromatiales	L	3'-5' exonuclease	-	-	-	ko:K07501	-	-	-	-	ko00000	-	-	-	DNA_pol_B_exo2
CMS1_k127_5519854_10	472759.Nhal_2445	7.287e-144	469.0	COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,1RN1D@1236|Gammaproteobacteria,1WWDA@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA	rlmD	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
CMS1_k127_5519854_7	323261.Noc_1344	2.716e-168	543.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,1RNES@1236|Gammaproteobacteria,1X2HE@135613|Chromatiales	135613|Chromatiales	E	PFAM Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
CMS1_k127_5519854_31	227377.CBU_1080	2.806e-59	211.0	COG1376@1|root,COG1376@2|Bacteria,1RHBG@1224|Proteobacteria,1S6DY@1236|Gammaproteobacteria,1JEG1@118969|Legionellales	118969|Legionellales	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
CMS1_k127_5519854_40	211165.AJLN01000140_gene2547	7.047e-40	168.0	COG0642@1|root,COG2202@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,1G2I4@1117|Cyanobacteria,1JH30@1189|Stigonemataceae	1117|Cyanobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9
CMS1_k127_5519854_14	105559.Nwat_0901	3.564e-114	375.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,1RNJ1@1236|Gammaproteobacteria,1WW7F@135613|Chromatiales	135613|Chromatiales	EP	PFAM Binding-protein-dependent transport	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_5519854_21	765912.Thimo_2071	4.237e-92	322.0	COG1173@1|root,COG1173@2|Bacteria,1MW3R@1224|Proteobacteria,1SYJC@1236|Gammaproteobacteria,1WW83@135613|Chromatiales	135613|Chromatiales	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_5519854_11	395493.BegalDRAFT_3022	5.572e-138	449.0	COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,1RMQF@1236|Gammaproteobacteria,45ZWB@72273|Thiotrichales	72273|Thiotrichales	G	Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides	nagZ	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
CMS1_k127_5519854_38	768671.ThimaDRAFT_4048	6.503e-41	163.0	COG3735@1|root,COG3735@2|Bacteria,1MVCW@1224|Proteobacteria,1RRI8@1236|Gammaproteobacteria,1WZGS@135613|Chromatiales	135613|Chromatiales	S	TraB family	-	-	-	ko:K09973	-	-	-	-	ko00000	-	-	-	TraB
CMS1_k127_5519854_12	1049564.TevJSym_ah00980	9.029e-135	439.0	COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria,1RNUB@1236|Gammaproteobacteria,1J51T@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	COG0668 Small-conductance mechanosensitive channel	ynaI	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0042802,GO:0044464,GO:0071944	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
CMS1_k127_5519854_19	1288826.MSNKSG1_17111	1.74e-95	320.0	COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,1RMGV@1236|Gammaproteobacteria,464H0@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
CMS1_k127_5519854_42	713586.KB900536_gene2181	4.675e-36	145.0	COG3159@1|root,COG3159@2|Bacteria,1R4BP@1224|Proteobacteria,1S9SC@1236|Gammaproteobacteria,1WY2X@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function, DUF484	-	-	-	ko:K09921	-	-	-	-	ko00000	-	-	-	DUF484
CMS1_k127_5519854_17	765912.Thimo_3276	1.169e-97	328.0	COG4973@1|root,COG4973@2|Bacteria,1MUJJ@1224|Proteobacteria,1RMJG@1236|Gammaproteobacteria,1WW4W@135613|Chromatiales	135613|Chromatiales	L	Belongs to the 'phage' integrase family. XerC subfamily	xerC	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
CMS1_k127_5519854_24	765911.Thivi_1736	1.181e-84	290.0	COG5405@1|root,COG5405@2|Bacteria,1MVF2@1224|Proteobacteria,1RP7P@1236|Gammaproteobacteria,1WVXJ@135613|Chromatiales	135613|Chromatiales	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
CMS1_k127_5519854_4	395493.BegalDRAFT_3532	7.319e-206	647.0	COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,1RMYV@1236|Gammaproteobacteria,4600H@72273|Thiotrichales	72273|Thiotrichales	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
CMS1_k127_5519854_36	1266914.ATUK01000011_gene2422	1.373e-48	175.0	COG3536@1|root,COG3536@2|Bacteria,1MZ5M@1224|Proteobacteria,1S8TB@1236|Gammaproteobacteria,1WYD9@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF971
CMS1_k127_5519854_20	1249634.D781_0214	2.873e-92	310.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,1RMAU@1236|Gammaproteobacteria,3ZZM8@613|Serratia	1236|Gammaproteobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008425,GO:0008757,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016741,GO:0030580,GO:0032259,GO:0042180,GO:0042181,GO:0043333,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b3833,iBWG_1329.BWG_3511,iE2348C_1286.E2348C_4147,iEC042_1314.EC042_4213,iEC55989_1330.EC55989_4310,iECDH10B_1368.ECDH10B_4024,iECDH1ME8569_1439.ECDH1ME8569_3712,iECH74115_1262.ECH74115_5274,iECIAI1_1343.ECIAI1_4028,iECIAI39_1322.ECIAI39_3162,iECO103_1326.ECO103_4330,iECO111_1330.ECO111_4661,iECO26_1355.ECO26_4752,iECSE_1348.ECSE_4121,iECSP_1301.ECSP_4888,iECUMN_1333.ECUMN_4359,iECW_1372.ECW_m4135,iECs_1301.ECs4763,iEKO11_1354.EKO11_4524,iETEC_1333.ETEC_4110,iEcDH1_1363.EcDH1_4146,iEcE24377_1341.EcE24377A_4354,iEcHS_1320.EcHS_A4057,iEcSMS35_1347.EcSMS35_4216,iEcolC_1368.EcolC_4175,iG2583_1286.G2583_4633,iJO1366.b3833,iJR904.b3833,iSBO_1134.SBO_3847,iSDY_1059.SDY_3910,iSFV_1184.SFV_3665,iSF_1195.SF3911,iSFxv_1172.SFxv_4263,iSSON_1240.SSON_4008,iS_1188.S3843,iSbBS512_1146.SbBS512_E4305,iUMNK88_1353.UMNK88_4663,iWFL_1372.ECW_m4135,iY75_1357.Y75_RS17910,iZ_1308.Z5355	Ubie_methyltran
CMS1_k127_5519854_44	870187.Thini_3067	1.736e-28	124.0	COG3165@1|root,COG3165@2|Bacteria,1R1CM@1224|Proteobacteria,1S1SM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	yigP	-	-	ko:K03690	-	-	-	-	ko00000	-	-	-	SCP2
CMS1_k127_5519854_3	187272.Mlg_0071	1.191e-214	679.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,1RNQM@1236|Gammaproteobacteria,1WWEC@135613|Chromatiales	135613|Chromatiales	S	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis	ubiB	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
CMS1_k127_5519854_33	1177154.Y5S_02132	2.829e-52	193.0	COG4700@1|root,COG4700@2|Bacteria,1R577@1224|Proteobacteria,1S5I8@1236|Gammaproteobacteria,1XPG4@135619|Oceanospirillales	135619|Oceanospirillales	S	protein conserved in bacteria containing a divergent form of TPR repeats	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_N
CMS1_k127_5519854_8	1173022.Cri9333_1431	4.12e-161	513.0	COG1064@1|root,COG1064@2|Bacteria,1G0B9@1117|Cyanobacteria,1H851@1150|Oscillatoriales	1117|Cyanobacteria	C	COG1064 Zn-dependent alcohol	-	-	-	ko:K13979	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_5519854_37	395493.BegalDRAFT_0480	1.483e-45	174.0	2DNTZ@1|root,32Z4F@2|Bacteria,1NA30@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
CMS1_k127_5519854_34	1198452.Jab_2c02510	9.913e-52	189.0	2EMEM@1|root,33F3F@2|Bacteria,1NK08@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5559459_13	202952.BBLI01000004_gene491	6.159e-16	78.0	2DR59@1|root,33A7S@2|Bacteria,1NMH2@1224|Proteobacteria,1SIVW@1236|Gammaproteobacteria,3NS87@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5559459_5	1026882.MAMP_02593	6.145e-117	399.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,1RMT5@1236|Gammaproteobacteria,45ZRN@72273|Thiotrichales	72273|Thiotrichales	O	Peptidylprolyl isomerase	-	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
CMS1_k127_5559459_7	1283300.ATXB01000001_gene1395	1.079e-109	368.0	COG0623@1|root,COG0623@2|Bacteria,1MV05@1224|Proteobacteria,1RNMW@1236|Gammaproteobacteria,1XDVR@135618|Methylococcales	135618|Methylococcales	I	Enoyl- acyl-carrier-protein reductase NADH	fabI	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
CMS1_k127_5559459_0	1049564.TevJSym_au00330	1.695e-306	954.0	COG4166@1|root,COG4166@2|Bacteria,1R87R@1224|Proteobacteria,1S4M3@1236|Gammaproteobacteria,1J5J7@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	hbpA	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
CMS1_k127_5559459_4	1288494.EBAPG3_26860	3.11e-154	492.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2WEDQ@28216|Betaproteobacteria,37232@32003|Nitrosomonadales	28216|Betaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	oppB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_5559459_2	765910.MARPU_03435	1.633e-176	565.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,1RND6@1236|Gammaproteobacteria,1WW5Y@135613|Chromatiales	135613|Chromatiales	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
CMS1_k127_5559459_1	472759.Nhal_0844	6.659e-208	659.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,1RMEI@1236|Gammaproteobacteria,1WWAN@135613|Chromatiales	135613|Chromatiales	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
CMS1_k127_5559459_10	1458357.BG58_16195	5.563e-60	213.0	COG0317@1|root,COG0317@2|Bacteria,1RGUA@1224|Proteobacteria,2VQUA@28216|Betaproteobacteria,1K6XY@119060|Burkholderiaceae	28216|Betaproteobacteria	KT	SMART metal-dependent phosphohydrolase, HD region	-	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	HD_4
CMS1_k127_5559459_12	1122134.KB893651_gene2010	3.629e-48	175.0	2CNK3@1|root,31TH7@2|Bacteria,1R38H@1224|Proteobacteria,1S7X7@1236|Gammaproteobacteria,1XKY6@135619|Oceanospirillales	135619|Oceanospirillales	S	Protein of Unknown function (DUF2784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2784
CMS1_k127_5559459_8	443144.GM21_1665	2.293e-97	331.0	COG1215@1|root,COG1215@2|Bacteria,1MW1E@1224|Proteobacteria,42ZKN@68525|delta/epsilon subdivisions,2WUTQ@28221|Deltaproteobacteria,43VG8@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
CMS1_k127_5559459_6	1479235.KK366039_gene1597	4.647e-112	374.0	COG3842@1|root,COG3842@2|Bacteria,1RC3N@1224|Proteobacteria,1RXZ2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,TOBE_2
CMS1_k127_5559459_9	522306.CAP2UW1_4207	6.781e-74	254.0	COG4149@1|root,COG4149@2|Bacteria,1MUXR@1224|Proteobacteria,2VIZW@28216|Betaproteobacteria,1KQRV@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
CMS1_k127_5559459_11	1121861.KB899919_gene2695	6.581e-50	188.0	COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,2U5B1@28211|Alphaproteobacteria,2JRR1@204441|Rhodospirillales	204441|Rhodospirillales	P	COG0725 ABC-type molybdate transport system, periplasmic component	modA	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
CMS1_k127_5559459_3	472759.Nhal_3170	1.894e-174	559.0	COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,1RMC0@1236|Gammaproteobacteria,1WVV8@135613|Chromatiales	135613|Chromatiales	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	-	-	1.8.1.7	ko:K00383	ko00480,ko04918,map00480,map04918	-	R00094,R00115	RC00011	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
CMS1_k127_5565374_1	402881.Plav_1318	1.599e-68	236.0	COG4122@1|root,COG4122@2|Bacteria,1QXHD@1224|Proteobacteria,2VF7P@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Macrocin-O-methyltransferase (TylF)	-	-	-	-	-	-	-	-	-	-	-	-	TylF
CMS1_k127_5565374_0	1479237.JMLY01000001_gene2949	1.398e-123	413.0	COG0501@1|root,COG0501@2|Bacteria,1MVU4@1224|Proteobacteria,1RPJ5@1236|Gammaproteobacteria,46584@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	COG0501 Zn-dependent protease with chaperone function	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
CMS1_k127_5650233_2	1469245.JFBG01000009_gene567	6.531e-107	352.0	COG0755@1|root,COG0755@2|Bacteria,1MU61@1224|Proteobacteria,1RP3R@1236|Gammaproteobacteria,1WX10@135613|Chromatiales	135613|Chromatiales	U	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmC	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
CMS1_k127_5650233_4	395493.BegalDRAFT_0735	3.902e-68	238.0	COG2386@1|root,COG2386@2|Bacteria,1NJB0@1224|Proteobacteria,1RRFJ@1236|Gammaproteobacteria,462B7@72273|Thiotrichales	72273|Thiotrichales	U	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	-	-	-	-	-	-	-	-	-	-	-	-	CcmB
CMS1_k127_5650233_6	395493.BegalDRAFT_0190	2.293e-53	196.0	COG4133@1|root,COG4133@2|Bacteria,1MZPC@1224|Proteobacteria,1S3R2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system	ccmA	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009898,GO:0015232,GO:0015886,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019897,GO:0019898,GO:0022857,GO:0031224,GO:0031234,GO:0032991,GO:0042623,GO:0043190,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051181,GO:0051184,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098533,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:1901678,GO:1902494,GO:1902495,GO:1904949,GO:1990351	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	iAPECO1_1312.APECO1_4358,iECED1_1282.ECED1_2666,iECS88_1305.ECS88_2348,iECUMN_1333.ECUMN_2536,iLF82_1304.LF82_0273,iNRG857_1313.NRG857_11170,iUMN146_1321.UM146_05800,iUTI89_1310.UTI89_C2479	ABC_tran
CMS1_k127_5650233_8	1123355.JHYO01000005_gene827	2.013e-24	111.0	COG0664@1|root,COG0664@2|Bacteria,1QERK@1224|Proteobacteria,2UGJU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
CMS1_k127_5650233_7	667014.Thein_0390	7.14e-37	153.0	COG3043@1|root,COG3043@2|Bacteria	2|Bacteria	C	anaerobic respiration	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
CMS1_k127_5650233_0	880073.Calab_1263	6.953e-179	576.0	COG3303@1|root,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
CMS1_k127_5650233_3	338969.Rfer_0258	3.706e-104	348.0	COG3391@1|root,COG3391@2|Bacteria,1MYI5@1224|Proteobacteria,2WEWP@28216|Betaproteobacteria	28216|Betaproteobacteria	G	6-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	NHL
CMS1_k127_5650233_1	338969.Rfer_0256	5.154e-110	366.0	COG3391@1|root,COG3391@2|Bacteria,1NT97@1224|Proteobacteria,2VNUX@28216|Betaproteobacteria	28216|Betaproteobacteria	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
CMS1_k127_5652566_3	1123228.AUIH01000004_gene1137	1.324e-103	340.0	COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,1RNA6@1236|Gammaproteobacteria,1XH98@135619|Oceanospirillales	135619|Oceanospirillales	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
CMS1_k127_5652566_6	395493.BegalDRAFT_3382	9.813e-23	107.0	COG3115@1|root,COG3115@2|Bacteria,1NMX8@1224|Proteobacteria,1SIUA@1236|Gammaproteobacteria,461GD@72273|Thiotrichales	72273|Thiotrichales	D	Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins	-	-	-	ko:K03528	-	-	-	-	ko00000,ko03036	-	-	-	ZipA_C
CMS1_k127_5652566_0	381666.H16_A2060	6.749e-251	791.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,2VIDE@28216|Betaproteobacteria,1K0GW@119060|Burkholderiaceae	28216|Betaproteobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
CMS1_k127_5652566_2	65093.PCC7418_1866	9.361e-166	544.0	COG1835@1|root,COG1835@2|Bacteria,1GB27@1117|Cyanobacteria	1117|Cyanobacteria	I	PFAM Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
CMS1_k127_5652566_5	1439940.BAY1663_01427	4.87e-24	103.0	2DNYP@1|root,32ZTI@2|Bacteria,1N747@1224|Proteobacteria,1SCCQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2905
CMS1_k127_5652566_1	1397527.Q670_10700	6.462e-228	724.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,1RMMD@1236|Gammaproteobacteria,1XH52@135619|Oceanospirillales	135619|Oceanospirillales	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
CMS1_k127_5652566_4	211586.SO_1342	1.557e-79	269.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,1RN64@1236|Gammaproteobacteria,2Q8RJ@267890|Shewanellaceae	1236|Gammaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006950,GO:0006970,GO:0008150,GO:0009266,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
CMS1_k127_5652566_7	765914.ThisiDRAFT_1138	1.207e-21	102.0	COG3073@1|root,COG3073@2|Bacteria,1N9FN@1224|Proteobacteria,1SGPC@1236|Gammaproteobacteria,1WYNC@135613|Chromatiales	135613|Chromatiales	T	PFAM Anti sigma-E protein RseA	-	-	-	ko:K03597	-	-	-	-	ko00000,ko03021	-	-	-	RseA_N
CMS1_k127_5652566_8	765914.ThisiDRAFT_1137	0.0003248	47.0	COG3026@1|root,COG3026@2|Bacteria,1MUQ8@1224|Proteobacteria,1RNF3@1236|Gammaproteobacteria,1WWVY@135613|Chromatiales	135613|Chromatiales	T	PFAM MucB RseB	-	-	-	ko:K03598	-	-	-	-	ko00000,ko03021	-	-	-	MucB_RseB,MucB_RseB_C
CMS1_k127_5652895_7	713586.KB900536_gene658	2.211e-35	135.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,1S8WZ@1236|Gammaproteobacteria,1WZ35@135613|Chromatiales	135613|Chromatiales	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
CMS1_k127_5652895_6	395493.BegalDRAFT_1894	3.407e-68	242.0	COG2935@1|root,COG2935@2|Bacteria,1MW62@1224|Proteobacteria,1RYD7@1236|Gammaproteobacteria,460JY@72273|Thiotrichales	72273|Thiotrichales	O	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate	ate	-	2.3.2.29	ko:K21420	-	-	R11547,R11548	RC00064	ko00000,ko01000	-	-	-	ATE_C,ATE_N
CMS1_k127_5652895_4	472759.Nhal_3735	3.502e-82	280.0	COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,1S1ZB@1236|Gammaproteobacteria,1WWJ2@135613|Chromatiales	135613|Chromatiales	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
CMS1_k127_5652895_1	395493.BegalDRAFT_2011	3.903e-116	385.0	COG3146@1|root,COG3146@2|Bacteria,1MU35@1224|Proteobacteria,1RNWI@1236|Gammaproteobacteria,4608J@72273|Thiotrichales	72273|Thiotrichales	S	Peptidogalycan biosysnthesis/recognition	-	-	-	ko:K09919	-	-	-	-	ko00000	-	-	-	FemAB_like
CMS1_k127_5652895_2	754476.Q7A_827	3.4e-110	366.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,1RN8W@1236|Gammaproteobacteria,462GF@72273|Thiotrichales	72273|Thiotrichales	BQ	histone deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
CMS1_k127_5652895_8	1121374.KB891586_gene2654	1.828e-32	130.0	COG4517@1|root,COG4517@2|Bacteria,1MZJX@1224|Proteobacteria,1S95D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	IV02_29925	-	-	-	-	-	-	-	-	-	-	-	DUF1820
CMS1_k127_5652895_0	866895.HBHAL_3428	8.068e-135	446.0	COG2978@1|root,COG2978@2|Bacteria,1TPDU@1239|Firmicutes,4HAWR@91061|Bacilli,3NDIW@45667|Halobacillus	91061|Bacilli	H	AbgT putative transporter family	-	-	-	ko:K12942	-	-	-	-	ko00000	-	-	-	ABG_transport
CMS1_k127_5652895_5	472759.Nhal_3806	1.032e-81	281.0	COG1073@1|root,COG1073@2|Bacteria,1RIWI@1224|Proteobacteria,1S0GF@1236|Gammaproteobacteria,1X0AW@135613|Chromatiales	135613|Chromatiales	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
CMS1_k127_5652895_3	1163409.UUA_15853	8.949e-105	357.0	COG1835@1|root,COG1835@2|Bacteria,1MV2W@1224|Proteobacteria,1RQS2@1236|Gammaproteobacteria,1X634@135614|Xanthomonadales	135614|Xanthomonadales	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
CMS1_k127_5704701_23	717231.Flexsi_0826	8.397e-43	158.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	ectC	-	4.2.1.108	ko:K06720	ko00260,ko01100,ko01120,map00260,map01100,map01120	M00033	R06979	RC01729	ko00000,ko00001,ko00002,ko01000	-	-	-	Ectoine_synth
CMS1_k127_5704701_6	123899.JPQP01000004_gene528	1.374e-89	304.0	COG5285@1|root,COG5285@2|Bacteria,1MWD5@1224|Proteobacteria,2VM24@28216|Betaproteobacteria,3T1BF@506|Alcaligenaceae	28216|Betaproteobacteria	Q	Ectoine hydroxylase	thpD	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016705,GO:0016706,GO:0019752,GO:0032787,GO:0042399,GO:0042400,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0051213,GO:0055114,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	1.14.11.55	ko:K10674	ko00260,ko01120,map00260,map01120	-	R08050	RC00661	ko00000,ko00001,ko01000	-	-	-	PhyH
CMS1_k127_5704701_25	261292.Nit79A3_2588	4.043e-35	136.0	COG2119@1|root,COG2119@2|Bacteria	2|Bacteria	O	membrane	-	-	-	-	-	-	-	-	-	-	-	-	UPF0016
CMS1_k127_5704701_18	335543.Sfum_3683	3.043e-48	181.0	2C0QF@1|root,32R7C@2|Bacteria,1MYZK@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5704701_26	1163617.SCD_n01815	2.146e-33	132.0	2B9KW@1|root,322Z5@2|Bacteria,1RJJB@1224|Proteobacteria,2VSVB@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5704701_13	686340.Metal_3155	2.222e-68	245.0	2CAM1@1|root,301FE@2|Bacteria,1RJ36@1224|Proteobacteria,1S7TX@1236|Gammaproteobacteria,1XFDM@135618|Methylococcales	135618|Methylococcales	S	Ceramidase	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase
CMS1_k127_5704701_10	305700.B447_08233	6.545e-77	265.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,2VHSA@28216|Betaproteobacteria,2KV15@206389|Rhodocyclales	28216|Betaproteobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	-	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
CMS1_k127_5704701_14	1163617.SCD_n01732	4.058e-65	231.0	28JUM@1|root,2Z9JN@2|Bacteria,1NDV6@1224|Proteobacteria,2VJ3P@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5704701_5	472759.Nhal_0029	7.252e-118	395.0	COG1565@1|root,COG1565@2|Bacteria,1N3CJ@1224|Proteobacteria,1RYCJ@1236|Gammaproteobacteria,1WWJG@135613|Chromatiales	135613|Chromatiales	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
CMS1_k127_5704701_11	765912.Thimo_0562	2.812e-72	256.0	COG1028@1|root,COG1028@2|Bacteria,1MUUV@1224|Proteobacteria,1RMJU@1236|Gammaproteobacteria,1WXHM@135613|Chromatiales	135613|Chromatiales	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	1.5.1.33	ko:K03793	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
CMS1_k127_5704701_35	105559.Nwat_1473	5.354e-06	55.0	2C8T8@1|root,32RMU@2|Bacteria,1N089@1224|Proteobacteria,1SAT4@1236|Gammaproteobacteria,1WYU4@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5704701_21	187272.Mlg_2523	3.3e-46	172.0	COG0801@1|root,COG0801@2|Bacteria,1RHNN@1224|Proteobacteria,1S62M@1236|Gammaproteobacteria,1WYX8@135613|Chromatiales	135613|Chromatiales	H	PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK	-	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
CMS1_k127_5704701_22	1177179.A11A3_07403	9.989e-46	167.0	COG1539@1|root,COG1539@2|Bacteria,1MZ8Z@1224|Proteobacteria,1S9B2@1236|Gammaproteobacteria,1XKFN@135619|Oceanospirillales	135619|Oceanospirillales	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
CMS1_k127_5704701_16	2340.JV46_25110	6.733e-55	200.0	COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,1RN1J@1236|Gammaproteobacteria,1J6BT@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
CMS1_k127_5704701_4	435908.IDSA_10735	9.821e-152	485.0	COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,1RN8M@1236|Gammaproteobacteria,2QFUP@267893|Idiomarinaceae	1236|Gammaproteobacteria	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
CMS1_k127_5704701_28	1122599.AUGR01000008_gene2549	1.062e-21	104.0	COG0828@1|root,COG0828@2|Bacteria,1MZCC@1224|Proteobacteria,1S8QZ@1236|Gammaproteobacteria,1XKFG@135619|Oceanospirillales	135619|Oceanospirillales	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
CMS1_k127_5704701_19	572477.Alvin_1841	1.679e-47	174.0	COG1610@1|root,COG1610@2|Bacteria,1RGZS@1224|Proteobacteria,1S61A@1236|Gammaproteobacteria,1WYDV@135613|Chromatiales	135613|Chromatiales	S	Yqey-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
CMS1_k127_5704701_2	1049564.TevJSym_ac02050	2.367e-169	550.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,1RMGA@1236|Gammaproteobacteria,1J4QZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	GO:0003674,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
CMS1_k127_5704701_1	1479237.JMLY01000001_gene1105	9.3e-231	730.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,1RMQI@1236|Gammaproteobacteria,464VE@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
CMS1_k127_5704701_32	243233.MCA2617	3.127e-14	76.0	2AY1G@1|root,31Q37@2|Bacteria,1QIYW@1224|Proteobacteria,1TGVJ@1236|Gammaproteobacteria,1XGT8@135618|Methylococcales	135618|Methylococcales	S	Domain of unknown function (DUF4404)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4404
CMS1_k127_5704701_31	110365.A0A023B5Q1	1.478e-15	87.0	2A37N@1|root,2RY4M@2759|Eukaryota,3YA0C@5794|Apicomplexa	5794|Apicomplexa	L	Endonuclease exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
CMS1_k127_5704701_30	247490.KSU1_B0703	7.568e-16	88.0	2EBDF@1|root,335E4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4878
CMS1_k127_5704701_0	1163617.SCD_n02239	2.976e-315	981.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2VH8J@28216|Betaproteobacteria	28216|Betaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copF	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase,YHS
CMS1_k127_5704701_24	1123508.JH636439_gene1397	1.453e-37	146.0	COG0789@1|root,COG0789@2|Bacteria,2J178@203682|Planctomycetes	203682|Planctomycetes	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR-DNA-bind
CMS1_k127_5704701_20	1304275.C41B8_11788	1.963e-46	169.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,1S3QE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	FG	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
CMS1_k127_5704701_3	519989.ECTPHS_01754	1.704e-158	506.0	COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria,1RMAA@1236|Gammaproteobacteria,1WWKJ@135613|Chromatiales	135613|Chromatiales	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	-	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
CMS1_k127_5704701_8	323261.Noc_2421	4.685e-85	289.0	COG1108@1|root,COG1108@2|Bacteria,1MVC2@1224|Proteobacteria,1RPYF@1236|Gammaproteobacteria,1WX5H@135613|Chromatiales	135613|Chromatiales	P	pfam abc-3	-	-	-	ko:K09816	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
CMS1_k127_5704701_7	338963.Pcar_3025	5.127e-86	290.0	COG1121@1|root,COG1121@2|Bacteria,1MUDW@1224|Proteobacteria,42NI8@68525|delta/epsilon subdivisions,2WKMZ@28221|Deltaproteobacteria,43U5P@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	PFAM ABC transporter related	-	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
CMS1_k127_5704701_12	472759.Nhal_2277	7.434e-69	243.0	COG0803@1|root,COG0803@2|Bacteria,1MVW9@1224|Proteobacteria,1T1Q3@1236|Gammaproteobacteria,1WXCI@135613|Chromatiales	135613|Chromatiales	P	PFAM periplasmic solute binding protein	-	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
CMS1_k127_5704701_15	472759.Nhal_2276	1.182e-61	216.0	COG0735@1|root,COG0735@2|Bacteria,1MZIW@1224|Proteobacteria,1S5ZI@1236|Gammaproteobacteria,1WYD6@135613|Chromatiales	135613|Chromatiales	P	Belongs to the Fur family	-	-	-	ko:K09823	ko02024,map02024	-	-	-	ko00000,ko00001,ko03000	-	-	-	FUR
CMS1_k127_5704701_29	187272.Mlg_0330	1.225e-17	87.0	COG0425@1|root,COG0425@2|Bacteria	2|Bacteria	O	sulfur carrier activity	tusA	GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0019725,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042592,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048878,GO:0051186,GO:0051188,GO:0051189,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0090407,GO:0097163,GO:0140104,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.1.14,2.8.1.7	ko:K00549,ko:K04085,ko:K04487	ko00270,ko00450,ko00730,ko01100,ko01110,ko01230,ko04122,map00270,map00450,map00730,map01100,map01110,map01230,map04122	M00017	R04405,R07460,R09365,R11528,R11529	RC00035,RC00113,RC01241,RC01789,RC02313	ko00000,ko00001,ko00002,ko01000,ko02048,ko03016,ko03029	-	-	-	TusA
CMS1_k127_5704701_27	313612.L8106_08046	1.149e-27	121.0	COG5001@1|root,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,1H7AX@1150|Oscillatoriales	1117|Cyanobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_4,Response_reg
CMS1_k127_5704701_34	551275.KB899544_gene1687	1.193e-06	59.0	COG2197@1|root,COG2204@1|root,COG2197@2|Bacteria,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	phcR	-	3.1.1.61,3.5.1.44	ko:K03412,ko:K03413,ko:K19622	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	HATPase_c,HDOD,Response_reg
CMS1_k127_5704701_17	1266925.JHVX01000007_gene2341	9.984e-54	192.0	COG1765@1|root,COG1765@2|Bacteria,1RCZW@1224|Proteobacteria,2VR62@28216|Betaproteobacteria,3735A@32003|Nitrosomonadales	28216|Betaproteobacteria	O	OsmC-like protein	yhfA	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
CMS1_k127_5704701_9	377629.TERTU_3126	2.137e-80	273.0	COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,1RMIZ@1236|Gammaproteobacteria,2PN0Z@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	T	helix_turn_helix, cAMP Regulatory protein	crp	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0007154,GO:0007584,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009605,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0009991,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016070,GO:0017076,GO:0018130,GO:0019001,GO:0019219,GO:0019222,GO:0019438,GO:0030551,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0032553,GO:0032555,GO:0032561,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0035438,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045013,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045990,GO:0046483,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0061984,GO:0061985,GO:0065007,GO:0070887,GO:0071496,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140110,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	Crp,cNMP_binding
CMS1_k127_5762817_3	323261.Noc_0946	8.045e-104	340.0	COG0755@1|root,COG0755@2|Bacteria,1MU61@1224|Proteobacteria,1RP3R@1236|Gammaproteobacteria,1WX10@135613|Chromatiales	135613|Chromatiales	U	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmC	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
CMS1_k127_5762817_12	243233.MCA0420	1.756e-06	53.0	COG3114@1|root,COG3114@2|Bacteria,1NGBM@1224|Proteobacteria,1SGGH@1236|Gammaproteobacteria,1XFW4@135618|Methylococcales	135618|Methylococcales	U	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	-	-	-	ko:K02196	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.107	-	-	CcmD
CMS1_k127_5762817_9	287.DR97_544	1.918e-47	174.0	COG2332@1|root,COG2332@2|Bacteria,1RHN5@1224|Proteobacteria,1SAQV@1236|Gammaproteobacteria,1YKSD@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	ccmE	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
CMS1_k127_5762817_0	395493.BegalDRAFT_2461	3.053e-255	803.0	COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,1RMY5@1236|Gammaproteobacteria,4623I@72273|Thiotrichales	72273|Thiotrichales	O	Cytochrome c-type biogenesis protein CcmF C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	CcmF_C,Cytochrom_C_asm
CMS1_k127_5762817_6	243233.MCA0417	2.298e-68	236.0	COG0526@1|root,COG0526@2|Bacteria,1RI3N@1224|Proteobacteria,1S5YV@1236|Gammaproteobacteria,1XF10@135618|Methylococcales	135618|Methylococcales	CO	TIGRFAM periplasmic protein thiol	-	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	Redoxin
CMS1_k127_5762817_10	1049564.TevJSym_ad01640	1.804e-34	138.0	COG3088@1|root,COG3088@2|Bacteria,1MZZ5@1224|Proteobacteria,1S9DV@1236|Gammaproteobacteria,1J6GH@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	subunit of a heme lyase	ccmH	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017004,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071840,GO:0071944,GO:0098552,GO:0098567	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH
CMS1_k127_5762817_7	697282.Mettu_2584	4.744e-63	234.0	COG4235@1|root,COG4235@2|Bacteria,1MY4J@1224|Proteobacteria,1RZEA@1236|Gammaproteobacteria,1XE56@135618|Methylococcales	135618|Methylococcales	O	TIGRFAM Cytochrome c-type biogenesis protein CcmI	-	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	-
CMS1_k127_5762817_11	488538.SAR116_0496	1.452e-17	90.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2TR2B@28211|Alphaproteobacteria,4BSDR@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	COG0790 FOG TPR repeat, SEL1 subfamily	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
CMS1_k127_5762817_1	1260251.SPISAL_08360	2.934e-239	754.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,1RMVN@1236|Gammaproteobacteria,1WW41@135613|Chromatiales	135613|Chromatiales	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
CMS1_k127_5762817_8	857087.Metme_0601	1.181e-49	184.0	COG1335@1|root,COG1335@2|Bacteria,1MWFQ@1224|Proteobacteria,1RMHF@1236|Gammaproteobacteria,1XFC0@135618|Methylococcales	135618|Methylococcales	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
CMS1_k127_5762817_2	472759.Nhal_3505	2.933e-116	389.0	COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,1RQQV@1236|Gammaproteobacteria,1WVXZ@135613|Chromatiales	135613|Chromatiales	MU	type I secretion outer membrane protein, TolC	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
CMS1_k127_5762817_5	396588.Tgr7_0485	4.827e-71	246.0	COG2518@1|root,COG2518@2|Bacteria,1RD6S@1224|Proteobacteria,1S0KH@1236|Gammaproteobacteria,1WX4D@135613|Chromatiales	135613|Chromatiales	O	PFAM protein-L-isoaspartate(D-aspartate) O-methyltransferase	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
CMS1_k127_5762817_4	105559.Nwat_0260	1.416e-89	301.0	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,1RP1F@1236|Gammaproteobacteria,1WX77@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
CMS1_k127_5846650_1	1123393.KB891333_gene2640	1.111e-140	457.0	COG0845@1|root,COG0845@2|Bacteria,1PJHF@1224|Proteobacteria,2VIRN@28216|Betaproteobacteria,1KSR8@119069|Hydrogenophilales	119069|Hydrogenophilales	M	HlyD family secretion protein	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_3
CMS1_k127_5846650_7	105559.Nwat_0364	2.073e-26	120.0	COG3794@1|root,COG3794@2|Bacteria,1MZWU@1224|Proteobacteria,1SDMY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	PFAM Copper binding proteins, plastocyanin azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
CMS1_k127_5846650_5	713586.KB900536_gene2245	7.125e-69	237.0	COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,1RPB6@1236|Gammaproteobacteria,1WY3D@135613|Chromatiales	135613|Chromatiales	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
CMS1_k127_5846650_2	1123368.AUIS01000005_gene373	3.818e-109	361.0	COG0421@1|root,COG0421@2|Bacteria,1MVV5@1224|Proteobacteria,1RMUT@1236|Gammaproteobacteria,2NCNK@225057|Acidithiobacillales	225057|Acidithiobacillales	H	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synt_N,Spermine_synth
CMS1_k127_5846650_0	1249627.D779_3092	1.716e-284	887.0	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,1RMM1@1236|Gammaproteobacteria,1WXBH@135613|Chromatiales	135613|Chromatiales	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
CMS1_k127_5846650_6	697282.Mettu_2144	6.057e-49	184.0	COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,1RMRZ@1236|Gammaproteobacteria,1XEXV@135618|Methylococcales	135618|Methylococcales	J	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
CMS1_k127_5846650_3	1523503.JPMY01000046_gene1200	1.134e-107	354.0	COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,1RNJK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	chromosome partitioning	parA	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
CMS1_k127_5846650_4	105559.Nwat_3137	1.353e-100	335.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,1RN65@1236|Gammaproteobacteria,1WWNZ@135613|Chromatiales	135613|Chromatiales	K	Belongs to the ParB family	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
CMS1_k127_5983987_2	331869.BAL199_30640	2.046e-65	237.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,4BR4G@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
CMS1_k127_5983987_4	1336237.JAEE01000001_gene1619	3.248e-07	52.0	2DT0U@1|root,33I6V@2|Bacteria,1NMHR@1224|Proteobacteria,1SGK7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_5983987_3	565045.NOR51B_2945	6.712e-22	98.0	COG2331@1|root,COG2331@2|Bacteria,1N6Q9@1224|Proteobacteria	1224|Proteobacteria	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
CMS1_k127_5983987_0	314278.NB231_09768	4.084e-272	848.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,1RNMI@1236|Gammaproteobacteria,1WXVV@135613|Chromatiales	135613|Chromatiales	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
CMS1_k127_5983987_1	1049564.TevJSym_aa01860	8.597e-71	243.0	COG1051@1|root,COG1051@2|Bacteria,1QTT4@1224|Proteobacteria,1RQ35@1236|Gammaproteobacteria,1J69Z@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	COG1051 ADP-ribose pyrophosphatase	nuhA	-	-	-	-	-	-	-	-	-	-	-	NUDIX
CMS1_k127_6085373_2	396588.Tgr7_3306	1.904e-117	384.0	COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,1RNWJ@1236|Gammaproteobacteria,1WW4K@135613|Chromatiales	135613|Chromatiales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
CMS1_k127_6085373_0	519989.ECTPHS_08818	2.478e-267	830.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,1RP4V@1236|Gammaproteobacteria,1WVYR@135613|Chromatiales	135613|Chromatiales	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
CMS1_k127_6085373_3	396588.Tgr7_3308	2.212e-43	164.0	COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,1S8X2@1236|Gammaproteobacteria,1WY1N@135613|Chromatiales	135613|Chromatiales	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
CMS1_k127_6085373_4	1266908.AQPB01000061_gene1362	8.712e-43	161.0	COG0711@1|root,COG0711@2|Bacteria,1RHZ0@1224|Proteobacteria,1S402@1236|Gammaproteobacteria,1WYT5@135613|Chromatiales	135613|Chromatiales	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
CMS1_k127_6085373_5	1049564.TevJSym_aq00410	1.446e-34	134.0	COG0636@1|root,32S3K@2|Bacteria,1N1NA@1224|Proteobacteria,1S9MD@1236|Gammaproteobacteria,1J6WA@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
CMS1_k127_6085373_1	1123392.AQWL01000013_gene2375	9.358e-124	402.0	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,2VHR5@28216|Betaproteobacteria,1KRNA@119069|Hydrogenophilales	119069|Hydrogenophilales	C	ATP synthase A chain	-	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
CMS1_k127_6085373_6	1288826.MSNKSG1_14532	3.51e-11	68.0	COG3312@1|root,COG3312@2|Bacteria,1N777@1224|Proteobacteria,1SD0Z@1236|Gammaproteobacteria,468Z4@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	COG3312 F0F1-type ATP synthase, subunit I	atpI	GO:0003674,GO:0003824,GO:0005215,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044769,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATP-synt_I
CMS1_k127_6105923_14	1215114.BBIU01000009_gene1508	4.012e-44	165.0	COG3749@1|root,COG3749@2|Bacteria,1RJR9@1224|Proteobacteria,1S64S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	IV02_15230	-	-	-	-	-	-	-	-	-	-	-	DUF934
CMS1_k127_6105923_1	1116472.MGMO_105c00200	5.291e-253	791.0	COG0155@1|root,COG0155@2|Bacteria,1MVVB@1224|Proteobacteria,1RMFH@1236|Gammaproteobacteria,1XEB1@135618|Methylococcales	135618|Methylococcales	C	reductase 4Fe-4S	-	-	1.8.1.2	ko:K00381	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00858	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
CMS1_k127_6105923_0	768671.ThimaDRAFT_3413	7.383e-282	880.0	COG0480@1|root,COG0480@2|Bacteria,1MVVY@1224|Proteobacteria,1RYCE@1236|Gammaproteobacteria,1WWXP@135613|Chromatiales	135613|Chromatiales	J	small GTP-binding protein	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
CMS1_k127_6105923_5	395493.BegalDRAFT_1809	1.739e-129	424.0	COG1485@1|root,COG1485@2|Bacteria,1MUUW@1224|Proteobacteria,1RMTJ@1236|Gammaproteobacteria,460G7@72273|Thiotrichales	72273|Thiotrichales	D	AFG1-like ATPase	zapE	-	-	ko:K06916	-	-	-	-	ko00000,ko03036	-	-	-	AFG1_ATPase
CMS1_k127_6105923_4	1123368.AUIS01000031_gene1422	1.75e-141	458.0	COG1533@1|root,COG1533@2|Bacteria,1MW0H@1224|Proteobacteria,1RQNF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
CMS1_k127_6105923_3	1123368.AUIS01000004_gene245	1.968e-144	471.0	COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,1RMB8@1236|Gammaproteobacteria,2NCQ4@225057|Acidithiobacillales	225057|Acidithiobacillales	S	RmuC family	-	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
CMS1_k127_6105923_9	870187.Thini_1499	4.729e-59	214.0	COG0637@1|root,COG0637@2|Bacteria,1PUMZ@1224|Proteobacteria,1RPII@1236|Gammaproteobacteria,46091@72273|Thiotrichales	72273|Thiotrichales	S	PFAM Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
CMS1_k127_6105923_6	1121878.AUGL01000009_gene3419	8.094e-98	352.0	COG0642@1|root,COG0834@1|root,COG5002@1|root,COG0642@2|Bacteria,COG0834@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	4HB_MCP_1,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg,SBP_bac_3,dCache_1
CMS1_k127_6105923_15	349124.Hhal_2173	1.613e-36	145.0	COG3065@1|root,COG3065@2|Bacteria,1MZ8C@1224|Proteobacteria,1S9UB@1236|Gammaproteobacteria,1WYVZ@135613|Chromatiales	135613|Chromatiales	M	PFAM Outer membrane lipoprotein Slp	-	-	-	ko:K07285	-	-	-	-	ko00000	-	-	-	Slp
CMS1_k127_6105923_2	1026882.MAMP_00661	2.063e-162	523.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,45ZQE@72273|Thiotrichales	72273|Thiotrichales	M	Belongs to the peptidase S1C family	-	-	-	ko:K04772	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
CMS1_k127_6105923_13	713587.THITH_01475	2.118e-49	180.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,1S607@1236|Gammaproteobacteria,1WYTK@135613|Chromatiales	135613|Chromatiales	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
CMS1_k127_6105923_7	1049564.TevJSym_ag00310	3.958e-65	229.0	COG2941@1|root,COG2941@2|Bacteria,1RAA1@1224|Proteobacteria,1RPMV@1236|Gammaproteobacteria,1J5PX@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	H	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol	coq7	-	-	ko:K06134	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00128	R04984,R08775	RC01254	ko00000,ko00001,ko00002,ko01000	-	-	-	COQ7
CMS1_k127_6105923_8	283942.IL0414	3.556e-63	222.0	COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,1S280@1236|Gammaproteobacteria,2QFZ1@267893|Idiomarinaceae	1236|Gammaproteobacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
CMS1_k127_6105923_10	1268237.G114_05660	2.483e-56	199.0	COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,1S3Q7@1236|Gammaproteobacteria,1Y4DN@135624|Aeromonadales	135624|Aeromonadales	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
CMS1_k127_6105923_16	243090.RB12778	1.143e-27	115.0	COG0399@1|root,COG0399@2|Bacteria,2J1H7@203682|Planctomycetes	203682|Planctomycetes	J	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
CMS1_k127_6105923_11	472759.Nhal_3721	5.152e-53	193.0	COG4520@1|root,COG4520@2|Bacteria,1N0YF@1224|Proteobacteria,1SAAR@1236|Gammaproteobacteria,1X1DX@135613|Chromatiales	135613|Chromatiales	M	17 kDa outer membrane surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	17kDa_Anti_2,Gly-zipper_Omp,Rick_17kDa_Anti
CMS1_k127_6105923_12	1304885.AUEY01000009_gene1939	1.96e-52	200.0	2B3X8@1|root,31WM6@2|Bacteria,1RFRT@1224|Proteobacteria,42SXT@68525|delta/epsilon subdivisions,2WPT2@28221|Deltaproteobacteria,2MKBX@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3999)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3999
CMS1_k127_6175874_7	1283300.ATXB01000001_gene1096	4.09e-53	193.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,1S610@1236|Gammaproteobacteria,1XFCX@135618|Methylococcales	135618|Methylococcales	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate	tsaC	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
CMS1_k127_6175874_0	472759.Nhal_3812	0.0	1045.0	COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,1MUFZ@1224|Proteobacteria,1RNZ2@1236|Gammaproteobacteria,1WWWP@135613|Chromatiales	135613|Chromatiales	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topo_Zn_Ribbon,Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
CMS1_k127_6175874_4	105559.Nwat_3069	1.52e-94	323.0	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,1RPJE@1236|Gammaproteobacteria,1WWKX@135613|Chromatiales	135613|Chromatiales	LU	TIGRFAM DNA protecting protein DprA	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
CMS1_k127_6175874_5	1026882.MAMP_00785	9.834e-90	310.0	COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,1RPMB@1236|Gammaproteobacteria,461TR@72273|Thiotrichales	72273|Thiotrichales	S	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
CMS1_k127_6175874_6	396588.Tgr7_0195	6.039e-63	220.0	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,1S247@1236|Gammaproteobacteria,1WXF4@135613|Chromatiales	135613|Chromatiales	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
CMS1_k127_6175874_3	61647.LG71_02505	7.842e-97	326.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,1RP1T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006418,GO:0006431,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019752,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	iECABU_c1320.ECABU_c37050,iECUMN_1333.ECUMN_3761,ic_1306.c4048	Formyl_trans_C,Formyl_trans_N
CMS1_k127_6175874_2	472759.Nhal_3818	9.743e-127	418.0	COG0144@1|root,COG0144@2|Bacteria,1MWPE@1224|Proteobacteria,1RN8X@1236|Gammaproteobacteria,1WVWG@135613|Chromatiales	135613|Chromatiales	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	-	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
CMS1_k127_6175874_8	243233.MCA2846	1.154e-28	124.0	29CX4@1|root,2ZZV8@2|Bacteria,1RFY7@1224|Proteobacteria,1SBT1@1236|Gammaproteobacteria,1XFDT@135618|Methylococcales	135618|Methylococcales	S	Domain of unknown function (DUF4390)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4390
CMS1_k127_6175874_1	1335757.SPICUR_00285	1.824e-136	454.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,1RQ8B@1236|Gammaproteobacteria,1WXE6@135613|Chromatiales	135613|Chromatiales	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,PAS_8
CMS1_k127_6227686_2	1198232.CYCME_2526	6.696e-16	78.0	COG0711@1|root,COG0711@2|Bacteria,1RHZ0@1224|Proteobacteria,1S402@1236|Gammaproteobacteria,460SP@72273|Thiotrichales	72273|Thiotrichales	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
CMS1_k127_6227686_1	1049564.TevJSym_aq00410	1.446e-34	134.0	COG0636@1|root,32S3K@2|Bacteria,1N1NA@1224|Proteobacteria,1S9MD@1236|Gammaproteobacteria,1J6WA@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
CMS1_k127_6227686_0	1123392.AQWL01000013_gene2375	1.746e-122	398.0	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,2VHR5@28216|Betaproteobacteria,1KRNA@119069|Hydrogenophilales	119069|Hydrogenophilales	C	ATP synthase A chain	-	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
CMS1_k127_6227686_3	1288826.MSNKSG1_14532	6.575e-11	68.0	COG3312@1|root,COG3312@2|Bacteria,1N777@1224|Proteobacteria,1SD0Z@1236|Gammaproteobacteria,468Z4@72275|Alteromonadaceae	1236|Gammaproteobacteria	C	COG3312 F0F1-type ATP synthase, subunit I	atpI	GO:0003674,GO:0003824,GO:0005215,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044769,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATP-synt_I
CMS1_k127_6248626_1	1122604.JONR01000003_gene1420	2.27e-187	593.0	COG2046@1|root,COG2046@2|Bacteria,1MUQB@1224|Proteobacteria,1RP4Q@1236|Gammaproteobacteria,1X4H5@135614|Xanthomonadales	135614|Xanthomonadales	P	PUA-like domain	-	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-sulfurylase,PUA_2
CMS1_k127_6248626_0	314278.NB231_13111	5.944e-232	722.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,1RP95@1236|Gammaproteobacteria,1WW22@135613|Chromatiales	135613|Chromatiales	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
CMS1_k127_6248626_2	265072.Mfla_2289	7.458e-38	143.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,2VSHX@28216|Betaproteobacteria,2KMW7@206350|Nitrosomonadales	206350|Nitrosomonadales	O	Belongs to the thioredoxin family	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
CMS1_k127_6273_2	1131553.JIBI01000017_gene553	4.13e-91	304.0	COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,2VH1C@28216|Betaproteobacteria,372CR@32003|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
CMS1_k127_6273_6	314278.NB231_01434	1.03e-26	114.0	COG3737@1|root,COG3737@2|Bacteria,1N083@1224|Proteobacteria,1SD91@1236|Gammaproteobacteria,1X23R@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF498/DUF598)	-	-	-	-	-	-	-	-	-	-	-	-	DUF498
CMS1_k127_6273_0	395493.BegalDRAFT_2435	2.761e-132	430.0	COG0568@1|root,COG0568@2|Bacteria,1MUDI@1224|Proteobacteria,1RN8V@1236|Gammaproteobacteria,461T2@72273|Thiotrichales	72273|Thiotrichales	K	Sigma-70 factor, region 1.2	rpoS	-	-	ko:K03087	ko02026,ko05111,map02026,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
CMS1_k127_6273_5	765914.ThisiDRAFT_1457	1.43e-56	209.0	COG4942@1|root,COG4942@2|Bacteria,1RD24@1224|Proteobacteria,1RR11@1236|Gammaproteobacteria,1WW55@135613|Chromatiales	135613|Chromatiales	DM	peptidase	-	-	-	ko:K06194	-	-	-	-	ko00000	1.A.34.1.2	-	-	LysM,Peptidase_M23
CMS1_k127_6273_3	396588.Tgr7_1433	2.528e-79	270.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,1RMHZ@1236|Gammaproteobacteria,1WX9P@135613|Chromatiales	135613|Chromatiales	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
CMS1_k127_6273_1	1123368.AUIS01000016_gene2540	5.557e-96	321.0	COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,1RN36@1236|Gammaproteobacteria,2NCKE@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
CMS1_k127_6273_4	1479237.JMLY01000001_gene1496	3.572e-68	234.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,1RQ59@1236|Gammaproteobacteria,465TZ@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3,2.1.3.6,2.1.3.9	ko:K00611,ko:K09065,ko:K13252	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01398,R07245	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
CMS1_k127_629726_3	519989.ECTPHS_01969	1.897e-202	642.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,1RMBS@1236|Gammaproteobacteria,1WXAR@135613|Chromatiales	135613|Chromatiales	NU	TIGRFAM type IV-A pilus assembly ATPase PilB	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
CMS1_k127_629726_7	472759.Nhal_3848	1.122e-162	521.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RNV0@1236|Gammaproteobacteria,1WWAB@135613|Chromatiales	135613|Chromatiales	U	Type II secretion system	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
CMS1_k127_629726_17	857087.Metme_0461	3.103e-102	340.0	COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,1RN90@1236|Gammaproteobacteria,1XDZI@135618|Methylococcales	135618|Methylococcales	NOU	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
CMS1_k127_629726_23	1283300.ATXB01000001_gene1290	7.567e-50	184.0	COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,1S3NR@1236|Gammaproteobacteria,1XF4I@135618|Methylococcales	135618|Methylococcales	F	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
CMS1_k127_629726_21	754477.Q7C_2224	4.124e-67	237.0	COG4582@1|root,COG4582@2|Bacteria,1MW69@1224|Proteobacteria,1RNPD@1236|Gammaproteobacteria,460VI@72273|Thiotrichales	72273|Thiotrichales	D	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity	zapD	-	-	ko:K18778	-	-	-	-	ko00000,ko03036	-	-	-	ZapD
CMS1_k127_629726_26	1304275.C41B8_04561	7.394e-10	63.0	COG3024@1|root,COG3024@2|Bacteria,1NGJ8@1224|Proteobacteria	1224|Proteobacteria	S	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase	yacG	GO:0003674,GO:0004857,GO:0005488,GO:0008150,GO:0008270,GO:0008657,GO:0010911,GO:0030234,GO:0032780,GO:0042030,GO:0043086,GO:0043167,GO:0043169,GO:0043462,GO:0044092,GO:0046872,GO:0046914,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0072586,GO:0098772,GO:2000371,GO:2000372	-	ko:K09862	-	-	-	-	ko00000	-	-	-	YacG
CMS1_k127_629726_19	323261.Noc_0306	1.892e-82	285.0	COG0352@1|root,COG0494@1|root,COG0352@2|Bacteria,COG0494@2|Bacteria,1RCZM@1224|Proteobacteria,1RS3S@1236|Gammaproteobacteria,1WW2I@135613|Chromatiales	135613|Chromatiales	HL	Thiamine monophosphate synthase	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX,NUDIX_4,TMP-TENI
CMS1_k127_629726_10	1265313.HRUBRA_00082	5.005e-141	458.0	COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,1RNVF@1236|Gammaproteobacteria,1J4SN@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
CMS1_k127_629726_0	105559.Nwat_0237	0.0	1254.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,1RM9M@1236|Gammaproteobacteria,1WWZC@135613|Chromatiales	135613|Chromatiales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
CMS1_k127_629726_20	323261.Noc_2852	4.658e-73	256.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,1RMIR@1236|Gammaproteobacteria,1WWMP@135613|Chromatiales	135613|Chromatiales	M	PFAM peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
CMS1_k127_629726_27	519989.ECTPHS_01914	6.412e-07	57.0	COG4701@1|root,COG4701@2|Bacteria,1N6NR@1224|Proteobacteria,1SEGX@1236|Gammaproteobacteria,1WZ6W@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
CMS1_k127_629726_9	1049564.TevJSym_aj00230	2.123e-146	468.0	COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,1RQ72@1236|Gammaproteobacteria,1J54C@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0008654,GO:0008759,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	3.5.1.108	ko:K02535	ko00540,ko01100,map00540,map01100	M00060	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iECS88_1305.ECS88_0100	LpxC
CMS1_k127_629726_6	472759.Nhal_0496	4.715e-164	524.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,1RPZS@1236|Gammaproteobacteria,1WXJ6@135613|Chromatiales	135613|Chromatiales	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
CMS1_k127_629726_1	396588.Tgr7_0774	2.31e-212	666.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,1RMXY@1236|Gammaproteobacteria,1WVUV@135613|Chromatiales	135613|Chromatiales	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
CMS1_k127_629726_22	105559.Nwat_0231	2.109e-51	192.0	COG1589@1|root,COG1589@2|Bacteria,1N0T7@1224|Proteobacteria,1S9FJ@1236|Gammaproteobacteria,1X2GI@135613|Chromatiales	135613|Chromatiales	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
CMS1_k127_629726_15	105559.Nwat_0230	2.164e-113	374.0	COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,1RMTM@1236|Gammaproteobacteria,1WWYB@135613|Chromatiales	135613|Chromatiales	M	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
CMS1_k127_629726_18	713586.KB900536_gene1371	2.151e-100	340.0	COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,1RNXK@1236|Gammaproteobacteria,1WW8T@135613|Chromatiales	135613|Chromatiales	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
CMS1_k127_629726_4	472759.Nhal_0491	8.083e-187	599.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,1RN88@1236|Gammaproteobacteria,1WW6B@135613|Chromatiales	135613|Chromatiales	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS1_k127_629726_14	1123399.AQVE01000003_gene2188	4.555e-115	382.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,1RMQ3@1236|Gammaproteobacteria,45ZMS@72273|Thiotrichales	72273|Thiotrichales	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
CMS1_k127_629726_12	395493.BegalDRAFT_0602	1.371e-119	396.0	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,1RMIV@1236|Gammaproteobacteria,45ZND@72273|Thiotrichales	72273|Thiotrichales	M	Peptidoglycan polymerase that is essential for cell division	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
CMS1_k127_629726_8	765912.Thimo_3113	1.242e-147	481.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,1RP25@1236|Gammaproteobacteria,1WWI1@135613|Chromatiales	135613|Chromatiales	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
CMS1_k127_629726_5	1469245.JFBG01000072_gene90	6.454e-168	535.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,1RNIG@1236|Gammaproteobacteria,1WWBT@135613|Chromatiales	135613|Chromatiales	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
CMS1_k127_629726_11	323261.Noc_2865	1.445e-129	428.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,1RMGD@1236|Gammaproteobacteria,1WWTC@135613|Chromatiales	135613|Chromatiales	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS1_k127_629726_13	1415754.JQMK01000002_gene2734	9.057e-116	391.0	COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,1RMD6@1236|Gammaproteobacteria,465IN@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	iECO103_1326.ECO103_0087,iECO111_1330.ECO111_0088,iECW_1372.ECW_m0084,iEKO11_1354.EKO11_3829,iWFL_1372.ECW_m0084,ic_1306.c0103	Mur_ligase,Mur_ligase_C,Mur_ligase_M
CMS1_k127_629726_2	396588.Tgr7_0763	2.498e-205	654.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,1RNGW@1236|Gammaproteobacteria,1WWDS@135613|Chromatiales	135613|Chromatiales	M	Catalyzes cross-linking of the peptidoglycan cell wall at the division septum	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
CMS1_k127_629726_25	713587.THITH_14500	1.621e-15	81.0	COG3116@1|root,COG3116@2|Bacteria,1NI3C@1224|Proteobacteria,1SGSB@1236|Gammaproteobacteria,1WZ00@135613|Chromatiales	135613|Chromatiales	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	ftsL	-	-	ko:K03586	-	-	-	-	ko00000,ko03036	-	-	-	FtsL
CMS1_k127_629726_16	406818.XBJ1_3484	5.94e-108	357.0	COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,1RM7M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
CMS1_k127_629726_24	1260251.SPISAL_06875	1.837e-39	151.0	COG2001@1|root,COG2001@2|Bacteria,1RHCG@1224|Proteobacteria,1S63F@1236|Gammaproteobacteria,1WYVR@135613|Chromatiales	135613|Chromatiales	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
CMS1_k127_629726_28	205914.HS_0917a	0.0001659	47.0	2E9J1@1|root,333RY@2|Bacteria,1NIX0@1224|Proteobacteria,1SGM0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_73779_5	519989.ECTPHS_01514	2.294e-53	193.0	COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,1RRP3@1236|Gammaproteobacteria,1WWF1@135613|Chromatiales	135613|Chromatiales	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
CMS1_k127_73779_2	236097.ADG881_662	6.295e-93	314.0	COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,1RPA9@1236|Gammaproteobacteria,1XIRE@135619|Oceanospirillales	135619|Oceanospirillales	E	Imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
CMS1_k127_73779_1	713587.THITH_15615	2.821e-159	506.0	COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,1RMM8@1236|Gammaproteobacteria,1WX13@135613|Chromatiales	135613|Chromatiales	H	Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX	hemF	GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983	1.3.3.3	ko:K00228	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03220	RC00884	ko00000,ko00001,ko00002,ko01000	-	-	-	Coprogen_oxidas
CMS1_k127_73779_4	765910.MARPU_00325	4.106e-59	207.0	COG1490@1|root,COG1490@2|Bacteria,1RGTV@1224|Proteobacteria,1S61I@1236|Gammaproteobacteria,1WYB4@135613|Chromatiales	135613|Chromatiales	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
CMS1_k127_73779_3	768671.ThimaDRAFT_1418	7.209e-82	278.0	COG0120@1|root,COG0120@2|Bacteria,1MVGR@1224|Proteobacteria,1RNF8@1236|Gammaproteobacteria,1WVVE@135613|Chromatiales	135613|Chromatiales	G	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate	rpiA	-	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A
CMS1_k127_73779_0	765914.ThisiDRAFT_0180	9.263e-203	644.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,1RMY6@1236|Gammaproteobacteria,1WWPJ@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
CMS1_k127_73779_6	523791.Kkor_2472	3.189e-34	133.0	COG2947@1|root,COG2947@2|Bacteria,1RHRU@1224|Proteobacteria,1S68X@1236|Gammaproteobacteria,1XK83@135619|Oceanospirillales	135619|Oceanospirillales	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
CMS1_k127_82457_2	290512.Paes_1895	4.425e-135	449.0	COG2989@1|root,COG2989@2|Bacteria,1FEJK@1090|Chlorobi	1090|Chlorobi	S	PFAM Peptidoglycan-binding domain 1 protein	-	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
CMS1_k127_82457_13	261292.Nit79A3_2844	1.638e-51	184.0	COG1553@1|root,COG1553@2|Bacteria,1N3C3@1224|Proteobacteria,2WCPP@28216|Betaproteobacteria,373SV@32003|Nitrosomonadales	28216|Betaproteobacteria	P	DsrE/DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
CMS1_k127_82457_17	555778.Hneap_1706	3.402e-36	138.0	COG0011@1|root,COG0011@2|Bacteria,1N1NM@1224|Proteobacteria,1SAV8@1236|Gammaproteobacteria,1WZPV@135613|Chromatiales	135613|Chromatiales	S	Thiamine-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Thiamine_BP
CMS1_k127_82457_0	1042377.AFPJ01000048_gene2676	3.075e-192	610.0	COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria,1RMXU@1236|Gammaproteobacteria,464J5@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K11928	-	-	-	-	ko00000,ko02000	2.A.21.2	-	-	SSF
CMS1_k127_82457_20	1279019.ARQK01000048_gene139	2.303e-26	109.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria,1WZ1Y@135613|Chromatiales	135613|Chromatiales	K	PFAM Cold-shock	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
CMS1_k127_82457_14	1198232.CYCME_0186	3.07e-50	185.0	COG3663@1|root,COG3663@2|Bacteria,1RAVZ@1224|Proteobacteria,1S2GN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Excises ethenocytosine and uracil, which can arise by alkylation or deamination of cytosine, respectively, from the corresponding mispairs with guanine in ds-DNA. It is capable of hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired base. The complementary strand guanine functions in substrate recognition. Required for DNA damage lesion repair in stationary-phase cells	mug	-	3.2.2.28	ko:K03649	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
CMS1_k127_82457_4	1049564.TevJSym_ab00790	4.675e-104	355.0	COG0642@1|root,COG0642@2|Bacteria,1MX6R@1224|Proteobacteria,1RPMH@1236|Gammaproteobacteria,1J85K@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
CMS1_k127_82457_6	1049564.TevJSym_ab00800	6.346e-88	295.0	COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,1S0IN@1236|Gammaproteobacteria,1JA2Q@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	K	Transcriptional regulatory protein, C terminal	IV02_26825	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
CMS1_k127_82457_24	1000565.METUNv1_00076	1.544e-16	83.0	COG3212@1|root,COG3212@2|Bacteria,1NHDB@1224|Proteobacteria,2VWE0@28216|Betaproteobacteria,2KX5T@206389|Rhodocyclales	206389|Rhodocyclales	S	Propeptide PepSY amd peptidase M4	-	-	-	-	-	-	-	-	-	-	-	-	PepSY
CMS1_k127_82457_16	1278309.KB907099_gene2594	3.969e-39	152.0	COG3658@1|root,COG3658@2|Bacteria,1N28F@1224|Proteobacteria,1S2S2@1236|Gammaproteobacteria,1XPRT@135619|Oceanospirillales	135619|Oceanospirillales	C	Dihaem cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	DHC
CMS1_k127_82457_18	395493.BegalDRAFT_0524	5.464e-36	141.0	COG2010@1|root,COG2010@2|Bacteria,1N1Z3@1224|Proteobacteria,1S8J5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Domain of unknown function (DUF1924)	shp	-	-	-	-	-	-	-	-	-	-	-	DUF1924
CMS1_k127_82457_10	572477.Alvin_0021	1.332e-59	212.0	COG3658@1|root,COG3658@2|Bacteria,1RIG7@1224|Proteobacteria,1S4KI@1236|Gammaproteobacteria,1WXNV@135613|Chromatiales	135613|Chromatiales	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
CMS1_k127_82457_8	177439.DP1202	6.275e-70	247.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42M5F@68525|delta/epsilon subdivisions,2WJ1T@28221|Deltaproteobacteria,2MHX9@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
CMS1_k127_82457_22	177439.DP2711	3.507e-21	100.0	COG1309@1|root,COG1309@2|Bacteria,1NCEF@1224|Proteobacteria,430I7@68525|delta/epsilon subdivisions,2WW5N@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
CMS1_k127_82457_7	1121920.AUAU01000023_gene2392	5.43e-86	295.0	2CCCK@1|root,2Z7UH@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AurF
CMS1_k127_82457_11	592015.HMPREF1705_02026	1.015e-56	206.0	COG0778@1|root,COG0778@2|Bacteria,3TCD8@508458|Synergistetes	508458|Synergistetes	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
CMS1_k127_82457_21	1121405.dsmv_0115	1.248e-24	105.0	COG3360@1|root,COG3360@2|Bacteria,1Q2I5@1224|Proteobacteria,42VRR@68525|delta/epsilon subdivisions,2WRD2@28221|Deltaproteobacteria,2MM5C@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
CMS1_k127_82457_9	522306.CAP2UW1_3067	2.46e-61	221.0	2A20V@1|root,30QAU@2|Bacteria,1RDQH@1224|Proteobacteria,2VQZV@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_82457_12	396588.Tgr7_3074	1.08e-55	201.0	COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,1RMXF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
CMS1_k127_82457_19	2340.JV46_13280	6.275e-32	128.0	2E1WQ@1|root,32X5W@2|Bacteria,1N2F8@1224|Proteobacteria,1SA2N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_82457_23	1283300.ATXB01000002_gene2926	3.823e-17	86.0	COG2128@1|root,COG2128@2|Bacteria,1N82C@1224|Proteobacteria,1RQQI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3179
CMS1_k127_82457_15	1417296.U879_06295	1.056e-39	154.0	COG3154@1|root,COG3154@2|Bacteria,1RH2M@1224|Proteobacteria,2UA8H@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	lipid carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
CMS1_k127_82457_1	1280944.HY17_08125	3.064e-146	471.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,2TS5M@28211|Alphaproteobacteria,43YK4@69657|Hyphomonadaceae	28211|Alphaproteobacteria	O	Peptidase family U32	yhbU	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32
CMS1_k127_82457_5	1188256.BASI01000005_gene2023	3.788e-89	303.0	COG0826@1|root,COG0826@2|Bacteria,1MWFW@1224|Proteobacteria,2TSF0@28211|Alphaproteobacteria,3FDQB@34008|Rhodovulum	28211|Alphaproteobacteria	O	Peptidase family U32	yhbV	-	-	-	-	-	-	-	-	-	-	-	Peptidase_U32
CMS1_k127_82457_3	1173264.KI913949_gene3524	2.792e-113	371.0	COG0513@1|root,COG0513@2|Bacteria,1G45Y@1117|Cyanobacteria	1117|Cyanobacteria	L	Belongs to the DEAD box helicase family	rhlE	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
CMS1_k127_855085_1	305900.GV64_13840	6.579e-40	154.0	COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,1S5WU@1236|Gammaproteobacteria,1XK9U@135619|Oceanospirillales	135619|Oceanospirillales	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
CMS1_k127_855085_0	713586.KB900536_gene192	9.885e-157	510.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,1RMIA@1236|Gammaproteobacteria,1WX0K@135613|Chromatiales	135613|Chromatiales	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3,DNA_pol3_tau_5
CMS1_k127_855085_3	998674.ATTE01000001_gene2228	7.463e-05	45.0	2E7GU@1|root,331ZI@2|Bacteria,1NEDQ@1224|Proteobacteria,1SG7K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4184)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4184
CMS1_k127_855085_2	1219035.NT2_08_01360	9.453e-11	63.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,2K2HE@204457|Sphingomonadales	204457|Sphingomonadales	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
CMS1_k127_950166_1	768671.ThimaDRAFT_1380	7.323e-124	408.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,1RP4T@1236|Gammaproteobacteria,1WX7G@135613|Chromatiales	135613|Chromatiales	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC2	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
CMS1_k127_950166_2	396588.Tgr7_0747	2.522e-102	347.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1X0EW@135613|Chromatiales	135613|Chromatiales	O	Trypsin	-	-	-	ko:K04691	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
CMS1_k127_950166_7	713586.KB900536_gene1396	7.601e-74	253.0	COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,1RP9H@1236|Gammaproteobacteria,1WWVC@135613|Chromatiales	135613|Chromatiales	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petA	-	1.10.2.2	ko:K00411	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,UCR_Fe-S_N
CMS1_k127_950166_0	754477.Q7C_2215	7.174e-203	637.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,1RNCP@1236|Gammaproteobacteria,45ZV4@72273|Thiotrichales	72273|Thiotrichales	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	-	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
CMS1_k127_950166_6	1026882.MAMP_01408	2.577e-74	257.0	COG2857@1|root,COG2857@2|Bacteria,1QFU2@1224|Proteobacteria,1RN4Y@1236|Gammaproteobacteria,460GB@72273|Thiotrichales	72273|Thiotrichales	C	PFAM Cytochrome C1	-	-	-	ko:K00413	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C1
CMS1_k127_950166_8	870187.Thini_1049	3.922e-62	220.0	COG0625@1|root,COG0625@2|Bacteria,1MXJD@1224|Proteobacteria,1RP12@1236|Gammaproteobacteria,460HZ@72273|Thiotrichales	72273|Thiotrichales	O	Stringent starvation protein A	-	-	-	ko:K03599	-	-	-	-	ko00000,ko02000,ko03021	1.A.12.3.1	-	-	GST_C,GST_N_3
CMS1_k127_950166_11	323261.Noc_0295	2.957e-36	141.0	COG2969@1|root,COG2969@2|Bacteria,1MZ2Q@1224|Proteobacteria,1S8WT@1236|Gammaproteobacteria,1WYWV@135613|Chromatiales	135613|Chromatiales	S	Stringent starvation protein B	-	-	-	ko:K03600	-	-	-	-	ko00000,ko03021	-	-	-	SspB
CMS1_k127_950166_9	1049564.TevJSym_ag00030	7.152e-61	214.0	COG2110@1|root,COG2110@2|Bacteria,1RCWP@1224|Proteobacteria,1S3WJ@1236|Gammaproteobacteria,1J689@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	phosphatase homologous to the C-terminal domain of histone macroH2A1	ymdB	GO:0003674,GO:0003824,GO:0004857,GO:0005488,GO:0005515,GO:0008150,GO:0008428,GO:0009892,GO:0010605,GO:0016787,GO:0019213,GO:0019219,GO:0019222,GO:0019899,GO:0030234,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0043086,GO:0043900,GO:0044092,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060698,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0061463,GO:0065007,GO:0065009,GO:0080090,GO:0098772,GO:1900190,GO:1900231	-	-	-	-	-	-	-	-	-	-	Macro
CMS1_k127_950166_10	1026882.MAMP_03126	1.52e-49	183.0	COG2823@1|root,COG2823@2|Bacteria,1MUZ2@1224|Proteobacteria,1RY2B@1236|Gammaproteobacteria,4619J@72273|Thiotrichales	72273|Thiotrichales	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
CMS1_k127_950166_5	1336245.JAGO01000010_gene679	2.78e-78	265.0	COG0279@1|root,COG0279@2|Bacteria,1NJ8X@1224|Proteobacteria,1RS1Y@1236|Gammaproteobacteria,1XI6S@135619|Oceanospirillales	135619|Oceanospirillales	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271,ko:K12961	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005,ko03036	-	-	-	SIS_2
CMS1_k127_950166_12	1452718.JBOY01000066_gene2386	5.615e-27	114.0	COG0792@1|root,COG0792@2|Bacteria,1N6VN@1224|Proteobacteria,1SC8A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Belongs to the UPF0102 family	yraN	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
CMS1_k127_950166_3	472759.Nhal_0475	2.32e-94	333.0	COG3107@1|root,COG3107@2|Bacteria,1MUHR@1224|Proteobacteria,1RXX4@1236|Gammaproteobacteria,1WX80@135613|Chromatiales	135613|Chromatiales	M	PFAM LppC	-	-	-	ko:K07121	-	-	-	-	ko00000	-	-	-	LppC
CMS1_k127_950166_4	322710.Avin_13150	1.591e-78	272.0	COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,1RM7U@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
CMS1_k127_950166_13	34506.g3068	6.477e-15	77.0	2D1ZE@1|root,2SJVP@2759|Eukaryota,3AI9D@33154|Opisthokonta,3BX0X@33208|Metazoa,3DEMU@33213|Bilateria	33208|Metazoa	S	LppC putative lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	LppC
CMS1_k127_958936_12	983545.Glaag_2138	1.242e-56	204.0	COG1091@1|root,COG1091@2|Bacteria,1MUXM@1224|Proteobacteria,1RSNR@1236|Gammaproteobacteria,4652A@72275|Alteromonadaceae	1236|Gammaproteobacteria	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
CMS1_k127_958936_9	1123368.AUIS01000003_gene1679	6.905e-91	301.0	COG1898@1|root,COG1898@2|Bacteria,1R9YD@1224|Proteobacteria,1S245@1236|Gammaproteobacteria,2NCIQ@225057|Acidithiobacillales	225057|Acidithiobacillales	G	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
CMS1_k127_958936_4	1123368.AUIS01000003_gene1680	3.288e-145	464.0	COG1209@1|root,COG1209@2|Bacteria,1MU0X@1224|Proteobacteria,1RMTR@1236|Gammaproteobacteria,2NBYJ@225057|Acidithiobacillales	225057|Acidithiobacillales	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
CMS1_k127_958936_11	269084.syc0603_c	2.333e-82	279.0	COG0529@1|root,COG0529@2|Bacteria,1G21C@1117|Cyanobacteria,1GZWS@1129|Synechococcus	1117|Cyanobacteria	F	Catalyzes the synthesis of activated sulfate	cysC	-	2.7.1.25	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R04928	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
CMS1_k127_958936_1	1121374.KB891587_gene3078	2.761e-207	651.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,1RMVW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	ugd	GO:0000271,GO:0003674,GO:0003824,GO:0003979,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016491,GO:0016614,GO:0016616,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046377,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901576	1.1.1.132,1.1.1.22	ko:K00012,ko:K00066	ko00040,ko00051,ko00053,ko00520,ko01100,ko02020,map00040,map00051,map00053,map00520,map01100,map02020	M00014,M00129,M00361,M00362	R00286,R00880	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	iEC55989_1330.EC55989_2287	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
CMS1_k127_958936_3	1399115.U719_14100	3.794e-153	495.0	COG0677@1|root,COG0677@2|Bacteria,1TPXY@1239|Firmicutes,4HAFY@91061|Bacilli,3WFGU@539002|Bacillales incertae sedis	91061|Bacilli	M	UDP-glucose GDP-mannose dehydrogenase	-	-	1.1.1.336	ko:K02472,ko:K02474	ko00520,ko05111,map00520,map05111	-	R03317,R06894	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
CMS1_k127_958936_6	177437.HRM2_29750	1.059e-123	404.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,42MWH@68525|delta/epsilon subdivisions,2WJMZ@28221|Deltaproteobacteria,2MI1B@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PFAM NAD dependent epimerase dehydratase family	uge	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
CMS1_k127_958936_16	202952.BBLI01000008_gene828	7.974e-10	59.0	2DTNT@1|root,33M3P@2|Bacteria,1NH3S@1224|Proteobacteria,1SGZB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
CMS1_k127_958936_2	519989.ECTPHS_05751	5.533e-195	617.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,1RN3R@1236|Gammaproteobacteria,1WW94@135613|Chromatiales	135613|Chromatiales	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
CMS1_k127_958936_8	1123401.JHYQ01000038_gene1583	8.445e-97	321.0	COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,1RNMK@1236|Gammaproteobacteria,45ZQ2@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
CMS1_k127_958936_13	1461577.CCMH01000013_gene717	3.823e-29	120.0	COG0399@1|root,COG0399@2|Bacteria,4PKRF@976|Bacteroidetes,1I4A2@117743|Flavobacteriia	976|Bacteroidetes	M	30S ribosomal protein S23	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
CMS1_k127_958936_0	1283300.ATXB01000001_gene875	5.114e-225	704.0	COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,1RMF6@1236|Gammaproteobacteria,1XEMR@135618|Methylococcales	135618|Methylococcales	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
CMS1_k127_958936_5	472759.Nhal_2510	3.206e-130	423.0	COG0604@1|root,COG0604@2|Bacteria,1MV3W@1224|Proteobacteria,1RMHG@1236|Gammaproteobacteria,1WX3U@135613|Chromatiales	135613|Chromatiales	C	PFAM Alcohol dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
CMS1_k127_958936_14	1122135.KB893135_gene777	6.889e-18	91.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2TR2B@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Sel1 domain protein repeat-containing protein	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
CMS1_k127_958936_7	336407.RBE_0084	1.634e-120	405.0	COG2227@1|root,COG4797@1|root,COG2227@2|Bacteria,COG4797@2|Bacteria,1QU8H@1224|Proteobacteria,2TWMI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	COG0500 SAM-dependent methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	MethyTransf_Reg,Methyltransf_25,Methyltransf_31
CMS1_k127_958936_15	1298867.AUES01000037_gene749	1.044e-17	85.0	COG1262@1|root,COG1262@2|Bacteria,1Q227@1224|Proteobacteria,2U2IQ@28211|Alphaproteobacteria,3K0RD@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	SapC	-	-	-	-	-	-	-	-	-	-	-	-	SapC
## 2130 queries scanned
## Total time (seconds): 32.15194797515869
## Rate: 66.25 q/s